bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between personality traits and situational anxiety about marriage in young people at the age of marriage
Authors: Shams Zahra 
Published: December 2020

This study was carried out with the aim of investigating the relationship between personality traits and situational anxiety about marriage in young people at the age of marriage. Correlational- descriptive research design used for this study. 50 young adults between 19 and 35 years residing in Tehran, after receiving information about research goals and giving their consent to participation, completed the NEO Five-Factor Inventory and situational anxiety questionnaire. Multiple correlation and multiple regression matrices used for analyzing the obtained data. The results indicated a positive correlation between situational anxiety and neuroticism (N), and a significant negative relationship between situational anxiety and extraversion (E), openness (O), agreeableness (A), and conscientiousness (C). Thus, the personality traits (OCEAN) were able to predict situational anxiety in young people at the age of marriage.
Keywords: personality traits, situational anxiety, marriage
INVENTÁRIO DE CONSUMO DE COMBUSTÍVEL, ESTIMATIVA DE EMISSÃO DE CO2 POR MONTE CARLO DAS EMBARCAÇÕES PETROLEIRAS, GRANELEIRAS E CONTÊINERES QUE OPERAM NO BRASIL
Authors: Jardim Luciana Suman 
Published: December 2020

De acordo a IMO (International Maritime Organisation) a navegação é responsável por 2,6% do total de emissão global dos gases de efeito estufa e os maiores contribuidores são os navios petroleiros, graneleiros e conteneiros, os quais também no período de 2012 a 2018 também eram os navios em maior quantidade operando em Águas Jurisdicionais Brasileiras – AJB. O estudo tem como objetivo inventariar, através de Monte Carlo, o consumo de combustível e estimar a quantidade de CO2 emitido através da queima de combustível fóssil utilizado pelas embarcações através de modelagem quantitativa, mensurando assim a parcela de responsabilidade do Brasil nas emissões mundiais calculadas pela IMO. Navios mais eficientes e com a menor quantidade de emissões é uma meta da comunidade marítima brasileira que apenas alcançaremos se soubermos qual o estado atual de contribuição dos navios na emissão do gás de efeito estufa – CO2, contribuindo assim efetivamente para a redução e/ou manutenção da atual temperatura do planeta.
Prima della tragedia. Militari italiani a Cefalonia e a Corfú
Authors: Branciforte Laura 
Published: December 2020

Patrizia Gabrielli, Prima della tragedia. Militari italiani a Cefalonia e a Corfú, Bologna, il Mulino, 2020, 173 384 págs., ISBN, 9788815275578 [Reseña]
Formulation Of A Rational Option Pricing Model
using Artificial Neural Networks
Authors: yadav Kaustubh , yadav Anubhuti 
Published: December 2020

This paper inquires on the options pricing modeling
using Artificial Neural Networks to price Apple(AAPL) European
Call Options. Our model is based on the premise that Artificial
Neural Networks can be used as functional approximators and
can be used as an alternative to the numerical methods to some
extent, for a faster and an efficient solution. This paper provides
a neural network solution for two financial models, the BlackScholes-Merton model, and the calibrated-Heston Stochastic
Volatility Model, we evaluate our predictions using the existing
numerical solutions for the same, the analytic solution for
the Black-Scholes equation, COS-Model for Heston’s Stochastic
Volatility Model and Standard Heston-Quasi analytic formula.
The aim of this study is to find a viable time-efficient alternative
to existing quantitative models for option pricing.
Introduction: International Conference Special Issue
Authors: Marshall P. David , Barbour Kim 
Published: December 2020

Scholarship and academic enquiry are complex entities. Individuals sequester themselves to complete their projects, publications, and manuscripts, and this solo activity can make us collectively think that the ivory tower of academic life is real. But the real hub of research, and its genuine success, is built from the process of exchange: conversations, discussions, engagements, re-readings and – building from this activity – amendments and integration of other related ideas, concepts, and trials. This journal has built from these exchanges as are the scholarly and academic personas (Barbour & Marshall 2012; Marshall, Barbour & Moore 2018) that we enact to present and perform our work: we depend on this “verkehr” (Marx & Engels 1970) to both advance our ideas and to ensure that those ideas (and our professional identities) have some impact and value.
Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans
Authors: Zhou Qinghua , Wan Qin-Li , Meng Xiao , Wang Chongyang , Dai Wenyu , Luo Zhenhuan , Fu Xiaodie , Yang Jing , Ye Qunshan , Zhang Zhan-Hui 
Published: December 2020

Abstract
As a major risk factor to human health, obesity presents a massive burden to people and society. Interestingly, the obese status of parents could affect progeny’s lipid accumulation through multi-generational epigenetic inheritance. To date, many questions remain as to how lipid accumulation leads to signals that are transmitted across generations. In this study, we established a model of C. elegans fed with a high fat diet (HFD) that led to obvious lipid accumulation, which can be propagated their progeny. Using this model, we discovered that transcription factors DAF-16/FOXO and SBP-1, nuclear receptors NHR-49 and NHR-80, and delta-9 desaturase (fat-5, fat-6, and fat-7) are required for transgenerational fat accumulation. Additionally, histone H3K4 tri-methylation (H3K4me3) marks genes related to lipid metabolism and increases their transcription response to multigenerational obesogenic effects. In summary, this study establishes that a network of lipid metabolic genes and chromatin modifications work together to achieve multigenerational obesogenic effects.
Malnutrition and Associated Factors in Admitted adult Surgical Patients in Eastern Ethiopia
Authors: Teklemariam Zelalem , Weldegebreal Fitsum , Mitiku Habtamu 
Published: December 2020

Abstract
Background: Malnutrition in surgical patients is found to be associated with reduced wound healing, increased complication rates, length of hospital stay, mortality, and healthcare costs than normally nourished patients. There are higher magnitude was reported from surgical patients in different studies abroad. However, there is no study conducted in eastern Ethiopia. Therefore, this study was aimed to assess magnitude of malnutrition and associated factors among adult surgical patients. Methods: Hospital based cross sectional study was conducted among 398 consecutively admitted surgical patients in Jugel and Hiwot Fana Specialized University Hospital from December 20, 2018 to November, 2019.Data was collected using pre tested structured questionnaire. Anthropometric measurements and dietary diversity assessment were made at admission and discharge of the patient. Capillary blood sample was collected for hemoglobin measurement. Data were analyzed using SPSS 20 software. Result: A total87(21.9%) and 99(24.9%) study participants were underweight at admission and discharge. Being male (AOR=0.40; 95CI: 0.21, 0.75) , age groups 18-40 years (AOR=0.22; 95 CI: 0.08, 0.62)and 41-60 years (AOR= 0.18; 95 CI: 0.06, 0.53) , urban residence (AOR= 0.38; 95% :0.17, 0.81) and Non anemic patients (AOR= 0.25; 95 CI:0.12, 0.48) were factors less likely to undernourished at admission. Being male (AOR= 0.39; 95% CI: 0.20, 0.76) ,age groups 18-40 (AOR= 0.14; 95 CI 0.04, 0.52) and 41-60 years (AOR=0.15; 95% CI: 0.04, 0.52) urban residents (AOR=0.26; 95 CI: 0.11, 0.57) , those with elective type of surgery (AOR=0.34; 95% CI: 0.14, 0.82) less likely, participants with hospital stay less than 5 days (AOR=0.14; 95 CI 0.02, 0.69) were factors less likely to undernourished at discharge.Conclusion: malnutrition /under nutrition is highly prevalent among surgical patients. Sex, age, residence and anemia were common factors associated with under nutrition at admission and discharge. In addition, type of current surgery and length of hospital stay were identified factors at time discharge. Therefore, the hospital staff should apply nutritional assessment and nutritional counseling /support to surgically admitted patients considering the identified factors.
Ultrasound-guided corticosteroid injection for patients with carpal tunnel syndrome: a systematic review and meta-analysis of randomized controlled trials
Authors: Yang Fu-An , Shih Ya-Chu , Hong Jia-Pei , Wu Chin-Wen , Liao Chun-De , Chen Hung-Chou 
Published: December 2020

Abstract
Carpal tunnel syndrome (CTS) refers to the symptoms and signs caused by the compression of the median nerve in the carpal tunnel. It can be treated by corticosteroid injection into the carpal tunnel. Two methods for injection have been employed, namely ultrasound-guided and landmark-guided injection. This systematic review and meta-analysis was conducted to compare these methods in terms of several outcomes. Randomized controlled trials (RCTs) were identified, and data collection was completed on 7 October 7, 2020. Results for continuous variables are expressed as standardized mean differences (SMDs) with 95% confidence intervals (CIs). Analyses were performed using RevMan 5.3 software. The analysis included eight RCTs published between 2013 and 2019 with a total of 448 patients. Ultrasound-guided injection yielded more favorable results for the Boston Carpal Tunnel Syndrome Questionnaire, Symptom Severity Scale [SMD = −0.49, 95% CI (−0.74, −0.25), P < 0.0001], Boston Carpal Tunnel Syndrome Questionnaire, Functional Status Scale [SMD = −0.24, 95% CI (−0.42, −0.06), P = 0.01], distal motor latency [SMD = −0.36, 95% CI (−0.70, −0.02), P = 0.04], and compound muscle action potential [SMD = 0.38, 95% CI (0.16, 0.61), P = 0.0008] . Ultrasound-guided corticosteroid injection is recommended for patients with CTS.
Integrative Taxonomy and Molecular Phylogeny of Three Poorly Known Tintinnine Ciliates, with the Establishment of a New Genus (Protozoa; Ciliophora; Oligotrichea)
Authors: Wang Rui , Bai Yang , Hu Tao , Xu Dapeng , Suzuki Toshikazu , Hu Xiaozhong 
Published: December 2020

Abstract
Background: The taxonomic classification of the suborder Tintinnina Kofoid & Campbell, 1929, a species-rich group of planktonic ciliated protozoans with characteristic lorica, is very ambiguous for a long time largely due to the lack of cytological and molecular data for most species. Among the group, Tintinnopsis is the largest, most widespread, and most taxonomically complex genus with about 170 species occurring in nearshore waters. The highly polyphyletic status of this speciose genus has also been revealed by previous researches.Results: We here first documented the live morphology, infraciliature, and molecular data, as well habitat characteristics of three poorly known tintinnine species, viz. Tintinnopsis karajacensis Brandt, 1896, Tintinnopsis gracilis Kofoid & Campbell, 1929, and Tintinnopsis tocantinensis Kofoid & Campbell, 1929, isolated from the coastal waters of China. Based on revelation of the unique cytological feature (the elongated ciliary tuft with densely arranged kinetids in it) in the former two species, which is apparently different from all other Tintinnopsis forms, Antetintinnopsis gen. nov. is thus erected with T. karajacensis designated as the type species. Moreover, these two species are placed in a highly supported clade, which branches away from other Tintinnopsis (including type species, T. beroidea) clades, in the phylogenetic analyses based on SSU rDNA and LSU rDNA sequences, which thus justifies the establishment of the new genus. Meanwhile, two other new combinations were made for Tintinnopsis hemispiralis and T. subacuta.Conclusions: The molecular data adopted here resulted in a well-resolved phylogenetic inference that provided strong evidence that the cytological characters are of valuable taxonomic delimitation for Tintinnina. This study also contributes to the broadening of our understanding of the tintinnine biodiversity and evolution.
Analysis of Growth and Physiological Variations Among Cyclocarya Species of Different Genotypes in a Clonal Seed Orchard
Authors: Feng Ying , Li Xiaofeng , Huang Junpo , Lin Guangxin , Yang Xinyu , Zheng Chenqi 
Published: December 2020

Abstract
Background: Cyclocarya paliurus (C. paliurus) is a woody species that has many medical benefits to human health. Geographical species has been formed among different natural forests of C. paliurus, but gradually decrease or extinct by human’s excessively exploitation in recent years. So, it is worthy to conserve this native and valuable species in China. Environmental factors affected plant growth, and seed is the only way for breeding offspring among Cyclocarya species, herein, we assess plant growth of six genotypes (FJ, JX, TG, WF, JH, AJ) from 2017 to 2019 year and physiological variations from April to October in 2018 during the construction of a clonal seed orchard.Results: The survival rate of plant reached 100% in a C. paliurus seed orchard. Plant height and basal diameter varied in different genotypes. Plant of six genotypes had different changes in water content and total soluble sugar content from April to October, Ca content reached maximum among the four detected mineral content, four kinds of antioxidant enzyme activity was in order of SOD＞PPO＞POD＞CAT, and the highest content of phytochemical was total flavonoid. Plant growth and physiological changes during growth period was significantly correlated with environment factors by correlation analysis. Conclusions: Plants of ex situ conservation adapted changeable environmental factors by physiological changes and showed the differentiation of plant growth in a clonal seed orchard. This would provide a foundation for ex situ conservation management in Cyclocarya species and selection of suitable cultivation provenance.
Bioinformatic Analysis Identifing FGF1&nbsp;Gene as a New Prognostic Indicator in Clear Cell Renal Cell Carcinoma&nbsp;
Authors: Zhang Xiaoqin , Wang Ziyue , Zeng Zixin , Shen Ningning , Wang Bin , Zhang Yaping , Shen Honghong , Lu Wei , Wei Rong , Ma Wenxia , Wang Chen 
Published: December 2020

Abstract
Background clear cell renal cell carcinoma (ccRCC) has been the commonest renal cell carcinoma (RCC). Although the disease classification, diagnosis and targeted therapy of RCC has been increasingly evolving attributing to the rapid development of current molecular pathology, the current situation is still challenge considering the comprehensive and progressively developing nature of malignant cancer. The study is to identify more potential responsible genes during the development of ccRCC using bioinformatic analysis, thus aiding more precise interpretation of the disease. Methods Firstly, different cDNA expression profiles from Gene Expression Omnibus (GEO) online database were used to screen the abnormal differently expressed genes (DEGs) between ccRCC and normal renal tissues. Then, based on the protein-protein interaction network (PPI) of all DEGs, the module analysis was performed to scale down the potential genes, and further survival analysis assisted our proceeding to the next step for selecting a credible key gene. Thirdly, immunohistochemistry (IHC) and quantitative real-time PCR (QPCR) were conducted to validate the expression change of the key gene in ccRCC comparing to normal tissues, meanwhile the prognostic value was verified using TCGA clinical data. Lastly, the potential biological function and signaling mechanism of gene regulation during ccRCC development was preliminary explored. Results Four cDNA expression profiles were picked from GEO database based on the number of containing sample cases, and a total of 192 DEGs, including 39 up-regulated and 153 down-regulated genes were shared in four profiles. Based on the DEGs PPI network, four function modules were identified highlighting a FGF1 gene involving PI3K-AKT signaling pathway which was shared in 3/4 modules. Further, both the IHC performed on 104 local ccRCC samples containing tissue microarray and QPCR conducted using 30 different samples confirmed that FGF1 was aberrant lost in ccRCC. And Kaplan-Meier overall survival analysis revealed that FGF1 gene loss was related to worse ccRCC patients survival. Lastly, the pathological clinical features of FGF1 gene and the probable biological functions and signaling pathways it involved were analyzed using TCGA clinical data. Conclusions Using bioinformatic analysis, we revealed that FGF1 expression was aberrant lost in ccRCC which correlated statistical significantly with patients survival, and the gene’s clinical features and potential biological functions were also explored. However, more detailed experiments and clinical trials are needed to support its potential drug-target role in clinical medical use.
Assessment of Corn Starch as Substitute for Agarose in DNA&nbsp;Gel Electrophoresis
Authors: Djankpa Francis Tanam , Wiafe Gideon Akuamoah , Boateng Bernard Ntim , Tsegah Korantema Mawuena , Essien-Baidoo Samuel , Ulanja Mark Bilinyi , Affram Kwame Ofori , Ussif Abdala Mumuni , Agyeman Desmond Owusu , Asante Gabriel 
Published: December 2020

Abstract
ObjectiveThe use of agarose in nucleic acid electrophoresis is the gold standard. However, agarose is very expensive and not readily available in resource limited developing countries like Ghana. Hence, finding a more affordable and readily available alternative to agarose will be a major boost to molecular research in developing countries. This study was aimed at investigating the use of corn starch as a potential substitute for agarose in DNA gel electrophoresis.ResultsGenomic DNA extracted from Plasmodium falciparum and primers were obtained from the West African Centre for Cell Biology of Infectious Pathogens and amplified using polymerase chain reaction. The amplicon was run on agarose gel to ascertain the molecular weight (as a positive control). When visualized under both blue light and ultraviolet light, the DNA and ladder showed clear and clean bands with the expected molecular weight. Corn starch was then modified with sodium borate buffer, casted into a gel and used to run the same DNA sample. Our findings indicated that similar to agarose, the DNA sample and ladder migrated successfully through the modified starch gel but no bands were visible when visualized under blue and ultra-violet light.
Availability of Standard Operating Guidelines for Primary Healthcare Facilities in Sub-saharan Africa: A Scoping Review Protocol
Authors: Sharpley Nelly , Kuupiel Desmond , Wyk Jacqueline Marina van 
Published: December 2020

Abstract
Background: Primary healthcare (PHC) clinics play an essential role in the delivery of community-based health services, particularly in resource-limited settings. However, there is little systematic documentation on the availability of standard operating guidelines governing their operation or evaluating the services provided by PHC facilities. This study, therefore, will aim to systematically map literature and describe the evidence on the availability of standard operating guidelines or procedures for PHC facilities in sub-Saharan Africa (SSA).Methods: This scoping review study will be conducted inline with the Arksey and O'Malley's framework. PubMed, EBSCOhost (Academic search complete, CINAHL with full text, and Health Sources), Scopus, and Google Scholar will be searched from 2010 to 2020 for relevant evidence sources using a search strategy comprising of keywords, Boolean terms, and medical subject headings. This study will include evidence sources/studies written/published in English that focused standard on standard operating guidelines for staffing and operational management, patient care and service provision, and quality monitoring procedures to assess the functioning of PHC facilities in SSA. The screening of the evidence sources/studies at all the stages and the data extraction will be conducted independently by two reviewers. Thematic analysis will be carried out to identify the themes and sub-themes and the findings relating to this study's research question summarised and reported for each theme narratively. Discussion: This scoping review anticipates to highlight standard operating guidelines available for staffing and operational management, patient care and service provision, and quality monitoring procedures to assess the functioning of PHC facilities to inform the development of relevant standard operating guidelines to improve healthcare services at the primary level. This study also anticipates revealing literature gaps for future research to ensure the attainment of universal health coverage by 2030.
Prokaryotic Argonaute From Archaeoglobus Fulgidus Interacts With DNA&nbsp;as a Homodimer
Authors: Golovinas Edvardas , Rutkauskas Danielis , Manakova Elena , Jankunec Marija , Silanskas Arunas , Sasnauskas Giedrius , Zaremba Mindaugas 
Published: December 2020

Abstract
Argonaute (Ago) proteins are found in all three domains of life. The best characterized group is eukaryotic Argonautes (eAgos), which are the core of RNA interference. The best understood prokaryotic Ago (pAgo) proteins are full-length pAgos. They are composed of four major structural/functional domains (N, PAZ, MID and PIWI) and thereby closely resemble eAgos. It was demonstrated that full-length pAgos function as prokaryotic antiviral systems, with the PIWI domain performing cleavage of invading nucleic acids. However, the majority of identified pAgos are shorter and catalytically inactive (encode just MID and inactive PIWI domains), thus their action mechanism and function remain unknown. In this work we focus on AfAgo, a short pAgo protein encoded by an archaeon Archaeoglobus fulgidus. We find that in all previously solved AfAgo structures, its two monomers form substantial dimerization interfaces involving the C-terminal β-sheets. Led by this finding, we have employed various biochemical and biophysical assays, including SEC-MALS, SAXS, single-molecule FRET and AFM, to show that AfAgo is indeed a homodimer in solution, which is capable of simultaneous interaction with two DNA molecules. This finding underscores the diversity of prokaryotic Agos and broadens the range of currently known Argonaute-nucleic acid interaction mechanisms.
Spontaneous Common Bile Duct Perforation in Full Term Pregnancy: A Rare Case Report and Review of Literature
Authors: Masroor Matiullah , Sarwari Mohammad Arif 
Published: December 2020

Abstract
Background: Spontaneous biliary system perforation is a rare presentation in clinical practice. It is even rare in adult population than infants. The condition is rarely suspected and diagnosed preoperatively because of small number of cases, vague sign and symptoms and ambiguous presentation.Case presentation: we are presenting an interesting case of spontaneous perforation of common bile duct in a 16 years old lady presented a week after her first delivery to the emergency department with complain of diffuse abdominal pain, abdominal distention, fever, vomiting and constipation. She was having generalize peritonitis but the cause of peritonitis was unknown despite of all available investigations performed. She underwent exploratory laparotomy and a perforation in the supra duodenal region of common bile duct was found intraoperatively. Common bile duct repair over T-tube and cholecystectomy performed and patient recovered.Conclusion: Spontaneous biliary perforation is a rare cause of acute abdomen in adults and extremely rare in pregnancy and its belated diagnoses and management is leading to high morbidity and mortality. All physicians especially surgeons should be aware of its possibility and consider it a cause of peritonitis on differential diagnosis especially when there is no apparent etiology available for the presentation.