bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is interdental papilla filling using hyaluronic acid a stable approach to treat black triangles? A systematic review
Authors: Ficho Ana Carolina , de Souza Faloni Ana Paula , Pennisi Pedro Rogério Camargo , Borges Lucas Gabriel França , de Macedo Bernadino Ítalo , Paranhos Luiz Renato , Queiroz Thallita Pereira , Santos Pâmela Letícia 
Published: December 2020

AbstractPurposeTo evaluate the stability of interdental papilla filling using hyaluronic acid (HA) to treat black triangles in esthetic regions.MethodsThe protocol was registered in PROSPERO. Six databases (PubMed, Scopus, Embase, Lilacs, SciELO, and Web of Science) were used as primary search sources, and OpenGrey and OpenThesis were used to capture the “gray literature.” Only before‐after studies were included. The JBI Checklist assessed the risk of bias. Only four studies met the inclusion criteria and were considered for the analyses. The studies were published from 2010 to 2016. All studies presented a low risk of bias. Considering the studies do not have control groups, a weighted average by sample size was calculated to obtain a general estimate of the percentage of papillary filling after 6 months and the number of HA applications.ResultsThe studies showed the percentage of papillary reconstruction after 6 months of application, the weighted average by sample size was 77.41% (SD = 20.68), with an average number of applications of 3.17 (SD = 0.31).ConclusionThe application of HA may be used to repair anesthetic defects in the papilla.Clinical significanceInterdental papilla reconstruction with injectable HA is an option of nonsurgical treatment for interdental papilla deficiencies. However, there is still concern about the quality of the evidence available, considering that studies with different experimental designs can produce contradictory results. Moreover, further understanding is required on the stability of tissue gain promoted by HA in black triangles.
Effect of modified atmosphere packaging materials on physicochemical and selected enzyme activities of Agaricus bernardii
Authors: Wang Limei , Chen Qianru , Zhang Jin , Cheng Peifang , Hu Jian , Dong Tungalag 
Published: December 2020

AbstractAgaricus bernardii was a typical mushroom in Inner Mongolia, China, with high metabolic rate, respiration rate and dehydration. The storage time of A. bernardii was very short. It was necessary to prolong postharvest storage. This study was to determine the physicochemical and selected enzyme activities of A. bernardii packed with different barrier packaging materials. The materials concluded low‐density polyethylene (PE), poly(butylene adipate‐co‐terephthalate)/poly(l‐lactic acid) (PBAT/PLLA), PBAT/PLLA/hydrophobic silica (0.5S SiO2) and polyamide/PE, respectively. The performance analysis of the materials, gas composition, sensory quality, physicochemical properties, nutritional quality, and index of senility of the mushrooms were measured. The results indicated that the low O2 (<1%) and moderate CO2 levels (4–7%) in 0.5S SiO2 film maintained a high level of soluble protein, soluble sugar, ascorbic acid, and phenolic contents, inhibited the increase of malondialdehyde, increased the antioxidant enzymes activities of peroxidase and decreased the enzymes activities of polyphenol oxidase. The quality index of the mushroom packed in the 0.5S SiO2 film remained a good condition and kept the market value after 15 days of storage.Practical applicationsThe biodegradable poly(butylene adipate‐co‐terephthalate)/poly(l‐lactic acid) (PBAT/PLLA/SiO2) film has a suitable water vapor permeability and CO2/O2 permeability radio, which could establish a suitable steady‐state inner atmosphere and maintain quality of mushrooms. Compared with the other films, PBAT/PLLA/SiO2 film kept the market value after 15 days of storage and the application of 0.5S SiO2 film could have potential on maintaining the quality of postharvest of Agaricus bernardii. Moreover, expected to replace the nondegradable food packaging material.
A rice tubulin tyrosine ligase‐like 12 protein affects the dynamic and orientation of microtubules
Authors: Zhang Kunxi , Zhu Xin , Durst Steffen , Hohenberger Petra , Han Min‐Jung , An Gynheung , Sahi Vaidurya P. , Riemann Michael , Nick Peter 
Published: December 2020

AbstractThe detyrosination/retyrosination cycle is the most common post‐translational modification of α‐tubulin. Removal of the conserved C‐terminal tyrosine of α‐tubulin by a still elusive tubulin tyrosine carboxypeptidase, and religation of this tyrosine by a tubulin tyrosine ligase (TTL), are probably common to all eukaryotes. Interestingly, for plants, the only candidates qualifying as potential TTL homologs are the tubulin tyrosine ligase‐like 12 proteins. To get insight into the biological functions of these potential TTL homologs, we cloned the rice TTL‐like 12 protein (OsTTLL12) and generated overexpression OsTTLL12‐RFP lines in both rice and tobacco BY‐2 cells. We found, unexpectedly, that overexpression of this OsTTLL12‐RFP increased the relative abundance of detyrosinated α‐tubulin in both coleoptile and seminal root, correlated with more stable microtubules. This was independent of the respective orientation of cortical microtubule, and followed by correspondingly changing growth of coleoptiles and seminal roots. A perturbed organization of phragmoplast microtubules and disoriented cell walls were further characteristics of this phenotype. Thus, the elevated tubulin detyrosination in consequence of OsTTLL12 overexpression affects structural and dynamic features of microtubules, followed by changes in the axiality of cell plate deposition and, consequently, plant growth.
Electroencephalographic functional connectivity is altered in persons with Down syndrome and Alzheimer's disease
Authors: Musaeus C. S. , Salem L. C. , Kjaer T. W. , Waldemar G. 
Published: December 2020

AbstractBackgroundPersons with Down syndrome (DS) are at increased risk of developing Alzheimer's dementia (DS‐AD). Due to heterogeneity in the functioning in persons with DS, it is difficult to use cognitive testing to assess whether a person with DS has developed dementia due to AD. Electroencephalography (EEG) functional connectivity has shown promising results as a diagnostic tool for AD in persons without DS. In the current exploratory study, we investigated whether EEG functional connectivity could be used as a diagnostic marker of AD in persons with DS and the association with symptoms.MethodsElectroencephalography from 12 persons with DS and 16 persons with DS‐AD were analysed, and both coherence and weighted phase lag index were calculated. In addition, we calculated the average coherence for fronto‐parietal and temporo‐parietal connections. Lastly, we investigated the correlation between the informant‐based Dementia Screening Questionnaire in Intellectual Disability (DSQIID) and total alpha coherence.ResultsDecreased alpha and increased delta coherence and weighted phase lag index were observed in DS‐AD as compared with DS. The decrease in alpha coherence was more marked in the fronto‐parietal connections as compared with the temporo‐parietal connections. No significant correlation was found between DSQIID and total alpha coherence (P value = 0.095, rho = −0.335).ConclusionThe decreased alpha coherence and weighted phase lag index have previously been found in AD. The increased delta coherence and weighted phase lag index may indicate a different initial neurophysiological presentation as compared with patients with AD or may be a sign of more advanced disease. Larger studies are needed to confirm the current findings.
“Pingpong racket” flap model for evaluating flap survival
Authors: Wu Lijun , Gao Suyue , Tian Kai , Zhao Tianlan , Li Ke 
Published: December 2020

AbstractBackgroundRandom skin flap is widely used to repair tissue defects; however, it is often accompanied by ischemia and necrosis of the distal flap due to inferior axial vascularity. Even though different drugs, biomaterials, and stem cell therapies have been developed to improve the survival of random flap, evaluating the promotion of flap survival remains a big challenge. Based on successful clinical practice, we designed a “Pingpong racket” shape flap in the rat. Without the predetected blood vessels procedure, the “pingpong racket” flap provides a preferable option to evaluate the function of drugs and biomaterials in promoting flap survival.Materials and methods“Pingpong racket” dorsal flaps with different pedicle lengths were developed in the rats. The survival area was evaluated by digital photography and computer‐assisted analysis. The quantitative survival area was considered a useful indicator for analyzing drugs' applicability in improving skin flap survival.ResultsA new model with a pedicle width of 1 cm and a flap diameter of 3 cm, in which the length of the pedicle could be tuned, was established. No iliolumbar vessels passed through the pedicle. The necrosis ratio ( round ) of the flap was 29.88% in the 2 cm long pedicle, 74.69% in the 3 cm long pedicle, 95.52% in the 4 cm long pedicle, and in the 5 cm long pedicle; necrotic area could be found in both the round part and in the pedicle.ConclusionThe new 3 cm long pedicle flap is suitable for evaluating the drugs for promoting skin flap survival. Rat dorsal “Pingpong racket” flap can be easily handled, thus avoiding blood vessels' detection. The flap could achieve comparable results to clinical and alleviate the negative influence of the flap's longitudinal contraction. Besides, it is intuitive and aesthetically pleasing.
Comparison of the effects of bilateral and unilateral laparoscopic ovarian drilling on pregnancy rates in infertile patients with polycystic ovary syndrome
Authors: Turgut Gokce D. , Mulayim Baris , Karadag Ceyda , Karadag Burak , Tatar Sezin A. , Yuksel Burcu A. 
Published: December 2020

AbstractAimThis study aims to investigate the effects of unilateral and bilateral laparoscopic ovarian drilling (LOD) on pregnancy rates in patients with clomiphene citrate (CC) resistant infertile polycystic ovary syndrome.MethodsThis prospective cohort study included 75 patients who were admitted to the Department of Obstetrics and Gynecology of the Antalya Training and Research Hospital between July 2016 and December 2017 and underwent LOD operation. Among these patients, 37 underwent unilateral laparoscopic ovarian drilling (ULOD) and 38 underwent bilateral laparoscopic ovarian drilling (BLOD). The drilling procedure was carried out using the following equation: Number of punctures (np) = 60 J/cm3/30 watt × 4 s by selecting the larger ovary in the patients who underwent ULOD and by taking the ovarian volume of each ovary in the BLOD group.ResultsDuring the 1‐year follow‐up, 20 of the ULOD patients (54.1%) and 13 of the BLOD patients (34.2%) were observed to be pregnant. Although a higher number of pregnancies were obtained in the ULOD group, no statistically significant difference was found between the two groups (P = 0.083). The pregnancies occurred more in the first 6 months during the postoperative follow‐ups of the patients. A total of 14 (70%) of the 20 pregnancies in the ULOD group and 9 (69.2%) of the 13 pregnancies in the BLOD group occurred in the first 6 months.ConclusionULOD with respect to a larger ovarian volume should be preferred to BLOD for CC‐resistant PCOS patients because of the high pregnancy rates and fewer potential side effects.
Effect of administration of monophasic oral contraceptive on the body composition and aerobic and anaerobic capacities of female athletes
Authors: Nakamura Mariko , Nose‐Ogura Sayaka 
Published: December 2020

AbstractAimTo examine the effects of administration of monophasic oral contraceptive (OC) on the body composition and aerobic and anaerobic capacities of female athletes.MethodsTen female athletes (23.0 ± 4.1 years old) participated in this study. All the subjects were examined during the menstrual cycle (early follicular [EF], middle luteal [ML]) and OC cycle (inactive OC, and active OC phases). After the menstrual cycle measurements, all the subjects began taking OC. The athletes tested using a body composition, circumferences, the lactate curve test, the maximal oxygen consumption test, and the Wingate test during all phases.ResultsWaist circumference was lower during the OC cycle than menstrual cycle (P < 0.05), and the other circumferences of parts were not different during the menstrual or OC cycles. However, there were no differences in body composition before and after taking OC. The phase of the menstrual or OC cycle did not affect maximal oxygen consumption, heart rate max or power output at a blood lactate concentration of 2 and 4 mmol/L between the menstrual and OC cycle phases. Although, the peak blood lactate level after the Wingate test was higher during the OC cycle (inactive OC phase, 13.0 ± 2.4 mmol/L; active OC phase, 12.4 ± 3.0 mmol/L) than during the menstrual cycle (EF phase, 11.9 ± 2.1 mmol/L; ML phase, 11.4 ± 2.1 mmol/L;P < 0.05), the peak and average power in the Wingate test did not change during the menstrual and OC cycle phases.ConclusionAdministration of monophasic OC did not affect the body composition or aerobic and anaerobic capacities of female athletes.
Effectiveness of 10% povidone‐iodine formulation on preoperative vaginal irrigation
Authors: Yoshida Tsukasa , Akitani Fumi , Hayashi Kuniyoshi , Shioda Kyoko 
Published: December 2020

AbstractAimTo investigate the effectiveness of 10% povidone‐iodine formulation as a vaginal irrigation agent in patients undergoing hysterectomy to prevent postoperative infection.MethodsThe prevalence of postoperative infection in 277 and 132 patients who underwent preoperative vaginal cleaning with 500 mL of distilled water and 20 mL of 10% povidone‐iodine solution, respectively, were compared in this retrospective study.ResultsPostoperative infection was observed in 15.6% of the overall patient population. The rate of postoperative infection was significantly higher in patients treated with 10% povidone‐iodine formulation than in those treated with distilled water (21.4% vs 12.8%, P = 0.040). Besides the agents of vaginal irrigation, operation time, length of hospital stay and rate of intraoperative complications affected the prevalence of postoperative infection. The multivariate analysis ranked the use of 10% povidone‐iodine formulation for vaginal irrigation as the second top factor contributing to postoperative infection (relative risk: 1.9 when compared to distilled water).ConclusionPreoperative vaginal irrigation with 10% povidone‐iodine formulation led to a significantly higher rate of postoperative infection than did preoperative vaginal irrigation with distilled water. For vaginal irrigation with povidone‐iodine, different concentrations and cleaning methods should be considered in the future.
Assessing Trust and Risk Perceptions in the Sharing Economy: An Empirical Study
Authors: Gu Huimin , Zhang Tingting (Christina) , Lu Can , Song Xiaoxiao 
Published: December 2020

AbstractThe sharing economy requires intensive interactions among multiple stakeholders, such as consumers, service providers, communities, and third‐party platforms. Undoubtedly, trust and risk perceptions could become the key for the success and sustainable development of this collaborative business. This study addresses the critical issue of the customers’ trust and risk perceptions in the sharing economy. With a sample size of 1,336 respondents, the study adopted a structural equation modelling technique to test a proposed structural model of this issue. The moderating role of social identity threats was included in the proposed model to further examine the relationships among sharing economy security factors and risk and trust perceptions. The findings identified four factors – rapport among stakeholders (customers, providers, communities), reliability of the transaction platform, facility quality, and share of value – that significantly influence the customers’ trust and risk perceptions and partially confirmed a moderating effect of social identity threats in the relationships. The study also provided empirical support for the link between trust and risk perceptions and positive outcomes (customer satisfaction, revisits, and positive word‐of‐mouth). Theoretical and practical implications are also discussed.
Bruxism: Best Evidence Consensus Statement
Authors: Goldstein Gary , DeSantis Louis , Goodacre Charles 
Published: December 2020

AbstractPurposeThe purpose of this Best Evidence Consensus Statement is to report on the prevalence, potential causes or association, treatment and cure of bruxism.Materials and MethodsA literature search limited to Clinical Trials, Randomized Controlled Trials, Systematic Reviews and Meta Analyses, with the key words bruxism, and prevalence identified 22 references, bruxism and causation 21, bruxism, and treatment 117, and bruxism and cure none.ResultsPrevalence received 5 references which were relevant to the question researched. Causation received 11 relevant references, treatment 34 relevant references and cure none. Eighteen additional references were culled from the reference lists in the aforementioned articles.ConclusionsDue to variations in demographics and the dependence on anamnestic data, the true prevalence of bruxism in any specific population is unknown. There is moderate evidence that psychosocial factors such as stress, mood, distress, nervousness, and feeling blue are associated with sleep bruxism (SB) as well as caffeine, alcohol, and smoking. There is no consensus on what symptoms of SB or awake bruxism (AB) should be treated. There is some evidence that occlusal devices and bio feedback therapies can be utilized in SB treatment. There is conflicting evidence in the use of Botulinum toxin A and no compelling evidence for the use of drug therapy to treat SB. There is not an established cure for bruxism. The clinician is best served in using caution in the dental rehabilitation of patients with severe occlusal wear.
Melatonin reverses the loss of the anticontractile effect of perivascular adipose tissue in obese rats
Authors: Gonzaga Natália A. , Awata Wanessa M. C. , Ficher Sabrina P. , Assis Victor O. , Alves Juliano V. , Tostes Rita C. , Tirapelli Carlos R. 
Published: December 2020

AbstractPerivascular adipose tissue (PVAT) undergoes functional changes in obesity. Increased oxidative stress is a central mechanism whereby obesity induces loss of the anticontractile effect of PVAT. Melatonin is an antioxidant that displays vasoprotective action in cardiovascular disease. Here, we sought to investigate whether melatonin would restore the anticontractile effect of periaortic PVAT in obesity. Male Wistar Hannover rats were treated for 10 weeks with a high‐calorie diet. Melatonin (5 mg/kg/d, p.o., gavage) was administered for 2 weeks. Functional findings showed that obesity‐induced loss of the anticontractile effect of PVAT and treatment with melatonin reversed this response. Tiron [a scavenger of superoxide anion (O2−)] restored the anticontractile effect of PVAT in aortas from obese rats, suggesting a role for reactive oxygen species (ROS) in such response. Decreased superoxide dismutase (SOD) activity and augmented levels of ROS were detected in periaortic PVAT from obese rats. These responses were accompanied by decreased levels of nitric oxide (NO) in PVAT. Treatment with melatonin restored SOD activity, decreased ROS levels, and increased NO bioavailability in PVAT from obese rats. Here, we first reported the beneficial effects of melatonin in periaortic PVAT in obesity. Melatonin reversed the adverse effects of obesity in PVAT that included overproduction of ROS, reduced SOD activity, and decreased bioavailability of NO. Therefore, PVAT may constitute an important target for the treatment of obesity‐induced vascular dysfunction and melatonin emerges as a potential tool in the management of the vascular complications induced by obesity.
Transatrial stenting for long‐term management of cardiac tumor obstruction of the right atrium in 3 dogs
Authors: Weisse Chick , Scansen Brian A. , Berent Allyson C. , Cober Rick E. 
Published: December 2020

AbstractBackgroundVenous obstruction in dogs caused by large intracardiac masses can result in severe morbidity with few safe treatments.Hypothesis/ObjectivesRetrospective study to report results after transatrial stent placement in dogs with naturally occurring cardiac masses causing venous obstruction.AnimalsThree client‐owned dogs diagnosed with large cardiac masses.MethodsRetrospective study of patients that received transatrial stents extending from the caudal vena cava, across the right atrium, and into the cranial vena cava (CrVC). Procedures, complications, and outcomes were recorded based upon medical records, referring veterinarians, and client communications.ResultsTwo dogs had similar clinical signs suggestive of congestive hepatopathy including marked ascites and lethargy. One dog had clinical signs of CrVC syndrome including head and neck swelling with pitting edema and pleural effusion. After stent placement, venous pressure gradients were decreased and repeat angiography confirmed that vascular patency was reestablished. Resolution of clinical signs was marked in all 3 dogs with only mild complications including tachyarrhythmias and hypertension in 1 dog during the perioperative period. Two dogs that required additional transatrial stent placement for reobstruction 6 and 14 months later improved after the second stent implantation. Survival times poststenting for the dogs were 3, 21, and 37 months, with cause of death related to the cardiac tumor in all dogs.Conclusions and Clinical ImportanceEndovascular transatrial stenting may provide a long‐term palliative treatment option for dogs with clinical signs attributable to tumor‐induced venous obstruction when more traditional treatments are declined or not indicated.
Identification of 5 novel feline erythrocyte antigens based on the presence of naturally occurring alloantibodies
Authors: Binvel Marie , Arsenault Julie , Depré Boris , Blais Marie‐Claude 
Published: December 2020

AbstractBackgroundSince the discovery of the Mik antigen, several studies have described blood incompatibilities unrelated to the AB system in cats.ObjectiveTo estimate the prevalence of cats with non‐AB incompatibilities associated with naturally occurring alloantibodies (NOAb), and to begin mapping the corresponding feline erythrocyte antigens (FEA).AnimalsTwo hundred and fifty‐eight type A cats.MethodsProspectively, cats were evaluated for the presence of NOAb by crossmatching in groups of 4‐6 cats. When NOAb were detected in a cat, its plasma was used as reagent to assess for the presence of the corresponding FEA in all cats included thereafter, and agreement observed between results of this extensive blood typing was evaluated.ResultsThe chance of detecting incompatibilities by randomly crossmatching 2 cats was 3.9%, which resulted in at least 7% of type A cats having NOAb. Blood typing and agreement analyses performed with 7 newly detected NOAb allowed the identification of 5 presumably distinct FEA. Feline erythrocyte antigens 1 and 5 were most frequent with prevalence of 84% and 96%, respectively. Only FEA 1‐negative status was associated with a higher risk of presenting NOAb; with 16.7% of 42 FEA 1‐negative cats having NOAb compared to 5.1% of 216 FEA 1‐positive cats.Conclusions and Clinical ImportanceThis study represents a first step of FEA identification outside the AB system. Because of its prevalence and association with NOAb, FEA 1 might correspond to theMikantigen.