bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fostering collisions in interdisciplinary graduate education
Authors: O’Meara KerryAnn , Culpepper Dawn 
Published: May 2020

PurposeUsing the lens of social physics, this study aims to examine how, if at all, one graduate training program fostered collisions or meaningful interactions, between students and faculty from different disciplinary backgrounds.Design/methodology/approachQualitative, ethnographic case study methods.FindingsThe University of Maryland’s National Research Traineeship program fostered collisions between students and faculty from different disciplinary backgrounds by facilitating exploration, idea flow and engagement within an interdisciplinary scholarly community. These collisions generated productive opportunities for student learning, development and collaborations, but at times also produced non-generative outcomes.Practical implicationsThis study names specific, strategic activities (e.g. regular research talks, physical space) that graduate programs can use to facilitate interdisciplinary collaborations among students and faculty and considers the extent to which such activities contribute to organizational change.Originality/valueThis paper applies new theories (collisions and social physics) to understanding interdisciplinary collaboration and identifies aspects of graduate training programs that may be replicable in other institutional settings.
The learning region tradition: a cultural reappraisal
Authors: Knudsen Jon P. 
Published: May 2020

PurposeThe learning region has over the years become popular as a concept to portray and analyse subnational geographic entities heading for future growth and well-being. Claiming analytic and political relevance, the concept nevertheless retains much unclarified ideological content.Design/methodology/approachThis study traces its roots to varieties of heterodox economic thinking where it has gained a prominent place.FindingsWhile being strong on the value of different kinds of knowledge to economic development, the concept has a much weaker grip on the cultural rationales for knowledge and learning.Originality/valueThus, the study concludes with a need for a cultural reorientation to take place if the concept is going to retain its significance in the future academically as politically.
Residents’ perceptions and attitudes towards tourism development: a perspective article
Authors: Rasoolimanesh S. Mostafa , Seyfi Siamak 
Published: May 2020

Purpose
This paper aims to briefly highlight the evolution and overview of theories and methods applied to studies on residents’ perceptions and attitudes towards tourism development and proposes several new areas of inquiry for future scholarly research.

Design/methodology/approach
This is a paper that highlights the past perspectives and future developments of residents’ impact perceptions of and attitudes towards tourism development.

Findings
This paper highlighted the theoretical and methodological perspectives of published articles in a few past decades on residents’ perceptions and attitudes. Moreover, this research showed that the future research on residents’ perceptions and attitudes should address emerging issues, such as over-tourism, as well as the technology-related factors. New theoretical and methodological perspectives are also proposed to investigate residents’ attitudes towards tourism development and its impacts.

Originality/value
This paper proposes several new areas of inquiry in relation to residents’ perceptions and attitudes towards tourism development for future research.
Tourism and the sustainable development goals in the Abaco cays: pre-hurricane Dorian in the Bahamas
Authors: Francis Raymond Maxwell , Nair Vikneswaran 
Published: May 2020

PurposeThe purpose of this paper is to explore how tourism investment, business and operations were aligned with the United Nations Sustainable Development Goals (SDGs) in the Abaco Cays pre-Hurricane Dorian 2019 in The Bahamas.Design/methodology/approachThis paper takes an exploratory qualitative approach using the Abaco Cays, The Bahamas as the geographical study area. Semi-structured interviews were conducted face-to-face for data collection and transcribed using NVivo 12 plus. Critical discourse analysis was used to interpret interviewees’ spoken words in the broader social context of the Abaco Cays.FindingsResults illustrate the extent of tourism alignment with the SDGs in communities, dependent on tourism for growth. Findings from tourism investment, business and operations data analysis provide insights on tourism and the SDGs from a local perspective.Research limitations/implicationsThis research demonstrates how tourism aligns with the SDGs in one geographical area of The Bahamas. It also highlights discourses influencing tourism and the SDGs towards achieving the 2030 Agenda.Practical implicationsA practical implication of this paper is adopting a bottom-up approach for a comprehensive understanding of tourism alignment with the SDGs in the Abaco Cays.Originality/valueThis paper provides implementation guidelines for communities in the Abaco Cays, to align local sustainable tourism plans with the SDGs. It also provides a multidisciplinary approach for greater coherence of tourism with the SDGs from the community to the national level in the Bahamas.
Characterization of acne patients carrying clindamycin‐resistant Cutibacterium acnes: A Japanese multicenter study
Authors: Nakase Keisuke , Aoki Sae , Sei Sayaka , Fukumoto Sana , Horiuchi Yuki , Yasuda Takae , Tanioka Miki , Sugai Junichi , Huh Wook‐Kang Winnie , Kakuta Mie , Nomoto Mayumi , Shimada Tokihiko , Watanabe Masako , Kobayashi Miwa , Murakami Saori , Takeo Chikage , Tsubouchi Rieko , Hayashi Nobukazu , Noguchi Norihisa 
Published: May 2020

AbstractUse of antimicrobials for acne treatment is correlated with an increased occurrence of antimicrobial‐resistant Cutibacterium acnes. To clarify the role of antimicrobial use on the resistance and to investigate the characteristics of resistant strains, we conducted a multicenter study in dermatological clinics frequently visited by new patients with acne vulgaris. We collected specimens in 264 acne patients and tested 164 C. acnes strains isolated from 164 patients visiting 13 dermatological clinics. Antimicrobial susceptibility testing showed that the rates of resistance for tetracyclines, macrolides and clindamycin were significantly higher in C. acnes strains isolated from patients using antimicrobials for acne treatment than patients not using them. In particular, clindamycin‐resistant strains were frequently isolated from patients with older median age (≥24 years) and severe/moderate acne. After investigating the resistance mechanism of 15 high‐level clindamycin‐resistant strains, the transposable clindamycin resistance genes, erm(X) or erm(50), were detected in 14 strains. Using single‐locus sequence typing for C. acnes, the strains with erm(X) or multidrug resistance plasmid pTZC1 coding erm(50) and tetracycline resistance gene tet(W) were classified into clade F, which were specifically isolated from Japanese patients with acne, except for one strain. Our data showed that patients’ information, such as antimicrobial use, age and acne severity, are valuable in estimating whether a patient carries antimicrobial‐resistant C. acnes. Additionally, our results suggest that the clade F strains have a high risk of acquiring multidrug resistance.
Behavioral parameters of six populations of Meccus phyllosomus longipennis (Heteroptera: Reduviidae) from areas with high and low prevalences of Trypanosoma cruzi human infection
Authors: Martínez‐Ibarra José Alejandro , Nogueda‐Torres Benjamín , Montañez‐Valdez Oziel Dante , Michel‐Parra J. Guadalupe , Ambriz‐Santos Miguel Ángel 
Published: May 2020

AbstractThree behaviors of epidemiological importance, namely feeding latency, feeding duration and defecation latency, for six populations of Meccus phyllosomus longipennis (Usinger) from areas of central, western and north‐central Mexico with high (HP) and low (LP) prevalence of Trypanosoma cruzi (Chagas) human infection were evaluated in this study. The median feeding latency (the time taken to begin feeding) was highly variable between instars. Within–instar comparisons showed that at least 65% of the LP populations (N3 to adult) started to feed significantly (P < 0.05) later than the HP population, with N1 showing no difference, and N2 from LP populations feeding sooner than those from HP populations. The six populations had similar median feeding durations within instars. A higher (P < 0.05) percentage of the instars from HP populations defecated faster than the respective instars from the three LP populations. Approximately 25% of the young nymphs (N1 to N3) and females in the HP populations defecated < 2 min postfeeding, compared with 4%–6% of the young nymphs and 1.3%–3% of females in the LP populations. Moreover, 17.7%–38.8% of the older nymphs (N4 to N5) in the HP populations and 6.8%–13.4% in the LP populations defecated during or immediately after feeding. Our results indicate that the HP populations have a greater potential than the LP populations to transmit T. cruzi infections, which may underlie the differences in the prevalence of T. cruzi infection in some areas where M. p. longipennis is currently distributed.
Effect of long‐term consumption of tea (Camellia sinensis L.) flower polysaccharides on maintaining intestinal health in BALB/c mice
Authors: Chen Dan , Ding Yu , Ye Hong , Sun Yi , Zeng Xiaoxiong 
Published: May 2020

AbstractPolysaccharides have various health‐promoting functions. However, dietary polysaccharides cannot be digested by the human alimentary tract, thus the gut is the most important location where polysaccharides play their role. The effect of polysaccharides from tea (Camellia sinensis L.) flower (TFPS) on intestinal health was investigated in the present study. TFPS with the molecular weight of 1,316.29 kDa was prepared, and twenty 6‐week‐old BALB/c male mice were randomly allotted to a chow diet (normal control group, NC group) or with 200 mg/kg (body weight)/day of TFPS for 13 weeks (n = 10 each). Histomorphology observation of jejunum and colons showed that TFPS maintained the adequate gut barrier. qPCR analysis revealed that the expression of colonic tight junction proteins of claudin1 (1.29 ± 0.15 compared with 1.00 ± 0.13, P < 0.05) and claudin5 (2.91 ± 0.44 compared with 1.00 ± 0.27, P < 0.01) at mRNA level with a significant difference between TFPS supplement or not, while the expression of TLR4 and TNF‐α mRNA was not changed statistically. 16S rDNA amplicons sequencing was applied to measure the compositions of gut microbiota from feces of mice. TFPS treatment exhibited similar relative abundances in Bacteroidetes and Firmicutes; however, it decreased the relative abundance of Akkermansia and increased that of Lactobacillus compared with the NC group. The contents of short‐chain fatty acids after TFPS supplementation, both in cecal contents and feces, were significantly higher than those of the NC group. Besides, TFPS significantly increased IgA production. These results suggest that TFPS is beneficial to intestinal health and can improve intestinal adaptive immune tolerance.Practical ApplicationDietary polysaccharides improve human intestinal health. Understanding the effect of TFPS, safe and healthy food components, on gut health increases the likelihood that TFPS will be developed as a functional food.
Methadone‐Assisted Opiate Withdrawal and Subsequent Heroin Abstinence: The Importance of Psychological Preparedness
Authors: Jones Steve , Jack Barbara , Kirby Julie , Wilson Thomas L. , Murphy Philip N. 
Published: May 2020

Background and ObjectivesTreatment guidelines emphasize patients’ readiness for transitioning from opiate substitution treatment (OST) to opiate withdrawal and abstinence. Psychological preparedness indicators for this transition were examined.MethodsPatients (all male) were recruited from three treatment settings: prison, an inpatient detoxification unit, and an outpatient clinic. Time 1 (T1) was admission to methadone‐assisted withdrawal in all settings. Time 2 (T2) was a 6‐month follow‐up. With n = 24 at T1 for each group (N = 72), a battery of instruments relevant to psychological preparedness was administered.ResultsAt T1, inpatients had higher self‐efficacy beliefs for successful treatment completion than prison patients. For patients contactable at T2, T1 self‐efficacy positively predicted T2 opiate abstinence. No other variable improved prediction. T1 SOCRATES (Stages of Change Readiness and Treatment Eagerness Scale) ambivalence scores, age, and lifetime heroin use duration predicted maintenance of contact or not with treatment services and contactability by the researcher. Measures of mood did not differ between groups at T1 or predict T2 outcomes.Discussion and ConclusionsSelf‐efficacy beliefs are a potentially useful indicator of readiness for transitioning from OST to a medically assisted opiate withdrawal and subsequent abstinence. Ambivalence regarding change, age, and lifetime heroin use duration are potentially useful predictors of patients maintaining contact with services, and of being retained in research.Scientific SignificanceThese findings advance existing literature and knowledge by highlighting the importance of self‐efficacy in psychological preparedness for opiate abstinence, and the predictive utility to clinicians of this and other variables measurable at admission, in the clinical management of opiate users. (© 2020 The Authors. The American Journal on Addictions published by Wiley Periodicals LLC on behalf of The American Academy of Addiction Psychiatry). (Am J Addict 2021;30:11–20)
Probabilistic borderwork
Authors: BOZÇALI FIRAT 
Published: May 2020

ABSTRACTHow are borders made porous? In Turkey's Kurdish borderlands, smugglers are not just agents who operate under cover of night, but city‐based traders whose legal practices create a third space in between legality and illegality. Kurdish oil traders accused of smuggling work closely with lawyers to perform what I call probabilistic borderwork. This is a deliberate counterstate political strategy that uses scientific uncertainty to challenge smuggling charges, achieve nonillegality, and legally disrupt the state's border enforcement. Going beyond existing categories of law and politics, probabilistic borderwork is not a rights‐claiming political‐legal action. Rather, it is a form of techno‐legal political agency involving collaboration between otherwise disparate professional groups. [oil, borders, law, techno‐politics, the Kurds, Turkey]
Augmentation of labor with oxytocin and its association with delivery outcomes: A large‐scale cohort study in 12 public hospitals in Nepal
Authors: Litorp Helena , Sunny Avinash K. , Kc Ashish 
Published: May 2020

AbstractIntroductionThe use of oxytocin to augment labor is increasing in many low‐resource settings; however, little is known about the effects of such use in contexts where resources for intrapartum monitoring are scarce. In this study, we sought to assess the association between augmentation of labor with oxytocin and delivery outcomes.Material and methodsWe conducted a cohort study in 12 public hospitals in Nepal, including all deliveries with and without augmentation of labor with oxytocin, but excluding elective cesarean sections, women with missing information on augmentation of labor, and women without fetal heart rate on admission. Bivariate and multivariate logistic regression calculating the crude and adjusted risk ratio (aRR) with corresponding 95% CI were performed, comparing (a) intrapartum stillbirth and first‐day mortality (primary outcome); and (b) intrapartum monitoring, mode of delivery, postpartum hemorrhage, bag‐and‐mask ventilation of the newborn, Apgar score, and neonatal death before discharge (secondary outcomes) among women with and without oxytocin‐augmented labor.ResultsThe total cohort consisted of 78 931 women, of whom 28 915 (37%) had labor augmented with oxytocin and 50 016 (63%) did not have labor augmented with oxytocin. Women with augmentation of labor had no increased risk of intrapartum stillbirth and first‐day mortality (aRR 1.24, 95% CI 0.65‐2.4), but decreased risks of suboptimal partograph use (aRR 0.71, 95% CI 0.68‐0.74), suboptimal fetal heart rate monitoring (aRR 0.50, 95% CI 0.48‐0.53), and emergency cesarean section (aRR 0.62, 95% CI 0.59‐0.66), and increased risks of bag‐and‐mask ventilation (aRR 2.1, 95% CI 1.8‐2.5), Apgar score <7 at 5 minutes (aRR 1.65, 95% CI 1.49‐1.86), and neonatal death (aRR 1.93, 95% CI 1.46‐2.56).ConclusionsAlthough augmentation of labor with oxytocin might be associated with beneficial effects, such as improved monitoring and a decreased risk of cesarean section, its use may lead to an increased risk of adverse perinatal outcomes. We urge for a cautious use of oxytocin to augment labor in low‐resource contexts, and call for evidence‐based guidelines on augmentation of labor in low‐resource settings.
Editorial: how widespread and serious is non‐alcoholic fatty liver disease in the real world?
Authors: Harris Rebecca , West Joe , Morling Joanne R. 
Published: May 2020

LINKED CONTENTThis article is linked to Loomba et al papers. To view these articles, visit https://doi.org/10.1111/apt.15679 and https://doi.org/10.1111/apt.15694.
Editorial: the most commonly used IBD indices still fail to represent real life and subjective patient experience. Author’s reply
Authors: Pariente Benjamin 
Published: May 2020

LINKED CONTENTThis article is linked to Lauriot dit Prevost et al and Creemers et al papers. To view these articles, visit https://doi.org/10.1111/apt.15681 and https://doi.org/10.1111/apt.15720.
Clinical and pathological characteristics of peripheral T‐cell lymphomas in a Spanish population: a retrospective study
Authors: Rodriguez‐Pinilla Socorro Maria , Domingo‐Domenech Eva , Climent Fina , Sanchez Joaquin , Perez Seoane Carlos , Lopez Jimenez Javier , Garcia‐Cosio Monica , Caballero Dolores , Blanco Muñez Oscar Javier , Carpio Cecilia , Castellvi Josep , Martinez Pozo Antonio , Gonzalez Farre Blanca , Bendaña Angeles , Aliste Carlos , Gonzalez Ana Julia , Gonzalez de Villambrosia Sonia , Piris Miguel A. , Gomez Codina Jose , Mayordomo‐Aranda Empar , Navarro Belen , Bellas Carmen , Rodriguez Guillermo , Borrero Juan Jose , Ruiz‐Zorrilla Ana , Grande Marta , Montoto Carmen , Cordoba Raul 
Published: May 2020

AbstractWe investigated the clinicopathological features and prognostic factors of patients with peripheral T‐cell lymphoma (PTCL) in 13 sites across Spain. Relevant clinical antecedents, CD30 expression and staining pattern, prognostic indices using the International Prognostic Index and the Intergruppo Italiano Linfomi system, treatments, and clinical outcomes were examined. A sizeable proportion of 175 patients had a history of immune‐related disorders (autoimmune 16%, viral infections 17%, chemo/radiotherapy‐treated carcinomas 19%). The median progression‐free survival (PFS) and overall survival (OS) were 7·9 and 15·8 months, respectively. Prognostic indices influenced PFS and OS, with a higher number of adverse factors resulting in shorter survival (P < 0·001). Complete response (CR) to treatment was associated with better PFS (62·6 vs. 4 months; P < 0·001) and longer OS (67·0 vs. 7·3 months; P < 0·001) compared to no CR. CD30 was expressed across all subtypes; >15% of cells were positive in anaplastic lymphoma kinase‐positive and ‐negative anaplastic large‐cell lymphoma and extranodal natural killer PTCL groups. We observed PTCL distribution across subtypes based on haematopathological re‐evaluation. Poor prognosis, effect of specific prognostic indices, relevance of histopathological sub‐classification, and response level to first‐line treatment on outcomes were confirmed. Immune disorders amongst patients require further examination involving genetic studies and identification of associated immunosuppressive factors.
The role of psychopathology in the relationship between history of maltreatment and suicide attempts among children and adolescent inpatients
Authors: Barbot Baptiste , Eff Henry , Weiss Shira R. , McCarthy James B. 
Published: May 2020

BackgroundThis retrospective chart review study investigates the relationship between the history of various forms of abuse and the presence of mood disorders and psychotic symptoms in predicting suicide attempts among psychiatrically hospitalized children and adolescents.MethodA multi‐mediation analysis was conducted with an archival dataset of 101 children and adolescents hospitalized predominantly for mood disorders and bipolar disorders with and without history of psychotic symptoms.ResultsResults showed that history of suicide attempts was directly associated with physical abuse and indirectly associated with sexual abuse (mediated by bipolar disorders). Emotional abuse was also indirectly related to history of suicide attempts, mediated by mood disorders for boys, and by psychotic symptoms for girls.ConclusionsThis study is among the first to differentiate the unique effects of different types of early maltreatment on psychopathology, particularly mood disorders and psychotic symptoms, and histories of suicide attempts in psychiatrically hospitalized children and youth.Key Practitioner Message

Little is known about the relationships between histories of maltreatment, psychopathology, and suicide (considered simultaneously) among hospitalized children and adolescents.

Different forms of abuse are associated with distinct psychopathology symptoms, and in turn, risk for suicide attempts.

Only physical abuse is directly related to a history of suicide attempts, while sexual and emotional abuse are indirectly related (mediated by mood disorders and psychotic symptoms).

These risk pathways are partly distinct for girls and boys.

Identifying unique and cumulated risk factors can help prevent suicidality among hospitalized youth.
Paired genetic analysis by next‐generation sequencing of lung cancer and associated idiopathic pulmonary fibrosis
Authors: Otsubo Kohei , Iwama Eiji , Ijichi Kayo , Kubo Naoki , Yoneshima Yasuto , Inoue Hiroyuki , Tanaka Kentaro , Osoegawa Atsushi , Tagawa Tetsuzo , Nakanishi Yoichi , Okamoto Isamu 
Published: May 2020

AbstractThe pathogenesis of lung cancer associated with idiopathic pulmonary fibrosis (IPF) has remained largely uncharacterized. To provide insight into this condition, we undertook genomic profiling of IPF‐associated lung cancer as well as of adjacent fibrosing lung tissue in surgical specimens. Isolated DNA and RNA from 17 IPF‐associated non‐small cell lung cancer and 15 paired fibrosing lung tissue specimens were analyzed by next‐generation sequencing with a panel that targets 161 cancer‐related genes. Somatic genetic alterations were frequently identified in TP53 (n = 6, 35.3%) and PIK3CA (n = 5, 29.4%) genes in tumor samples as well as in EGFR (n = 7, 46.7%), PIK3CA (n = 5, 33.3%), ERBB3 (n = 4, 26.7%), and KDR (n = 4, 26.7%) in IPF samples. Genes related to the RAS‐RAF signaling pathway were also frequently altered in tumor (n = 7, 41.2%) and IPF (n = 3, 20.0%) samples. The number of somatic alterations identified in IPF samples was almost as large as that detected in paired tumor samples (81 vs 90, respectively). However, only 6 of the 81 somatic alterations detected in IPF samples overlapped with those in paired tumor samples. The accumulation of somatic mutations was thus apparent in IPF tissue of patients with IPF‐associated lung cancer, and the RAS‐RAF pathway was implicated in lung tumorigenesis. The finding that somatic alterations were not frequently shared between tumor and corresponding IPF tissue indicates that IPF‐associated lung cancer does not develop through the stepwise accumulation of somatic alterations in IPF.