bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive Technologies in the Management and Formation of Directions of the Priority Development of Industrial Enterprises
Authors: Kwilinski Aleksy , Kuzior Aleksandra 
Published: May 2020

Abstract
The possibilities of using cognitive technologies in the organization of systematic industrial enterprise management are described in the article. Strategic links are defined in the development of a system of stochastic models of enterprise management based on artificial intelligence. The possibility of introduction of the Perceptron model in the industrial enterprise management with the purpose of identification of “bottlenecks” in the functionality of business activity and improvement of procedures of decision-making in the framework of creation of the program of development and technical re-equipment of the enterprise is proven. The authors offered an organizational and economic mechanism of operation of an industrial enterprise, which includes new means of implementation of managerial actions through the use of a matrix of assessment of the level of implementation of cognitive technologies. The method of determining priority directions for the implementation of cognitive technologies at an enterprise was developed based on the results of the assessment of the depth of penetration of cognitive technologies and the result obtained from their implementation, which additionally takes into account the resource ratio of the implemented technologies defined as the ratio of estimates of the actual level of competencies to what is needed to work with new cognitive technologies, which allows to obtain the planned economic and organizational effect.
The prevalence of occult ovarian cancer in the series of 155 consequently operated high risk asymptomatic patients – Slovenian population based study
Authors: Gornjec Andreja , Merlo Sebastijan , Novakovic Srdjan , Stegel Vida , Gazic Barbara , Perhavec Andraz , Blatnik Ana , Krajc Mateja 
Published: May 2020

Abstract

Background
We assessed the prevalence, localization, type and outcome of occult cancer at risk-reducing salpingo-oophorectomy or salpingectomy (RRSO) in asymptomatic carriers of pathogenic or likely pathogenic BRCA1/2 variants and high-risk BRCA1/2 negative women.

Patients and methods
A retrospective analysis of all consecutive gynaecologic preventive surgeries from January 2009 to December 2015 was performed. Participants underwent genetic counselling and BRCA1/2 testing before the procedure. Data on clinical parameters, adjuvant treatment and follow-up were collected and analysed.

Results
One hundred and fifty-five RRSO were performed in 110 BRCA1, 35 BRCA2 carriers of pathogenic or likely pathogenic variants and 10 high-risk BRCA1/2 negative women, at the mean age of 48.3 years. Nine occult cancers (9/155, 5.8%) were identified; eight in BRCA1 positive women and one in high-risk BRCA1/2 negative woman. We identified four non-invasive serous intraepithelial tubal carcinomas (3 in BRCA1 carriers and 1 in a high-risk BRCA1/2 negative woman) and five invasive tubo-ovarian high grade serous cancers (all detected in BRCA1 carriers). Only one out of nine patients (11.1%) with occult cancer had a slightly elevated CA-125 value preoperatively.

Conclusions
A 5.8% prevalence of occult invasive and noninvasive tubo-ovarian serous cancer after RRSO was found in high risk asymptomatic and screen negative women. We conclude that RRSO should be performed in BRCA1/2 carriers and in high-risk BRCA1/2 negative women. Age of preventive gynaecologic surgery should be carefully planned, taking into account the completion of childbearing age and type of mutation. The results favour the tubal hypothesis of tubal origin of high grade serous ovarian and peritoneal cancer. Cytology result of peritoneal cavity washing was important for the decision making process in determining treatment. Cytology examination should be performed in all cases of RRSO. CA-125 assay did not prove to be an effective screening tool for early cancer detection in our patients.
Care of patients with non-small-cell lung cancer stage III – the Central European real-world experience
Authors: Zemanova Milada , Pirker Robert , Petruzelka Lubos , Zbozínkova Zuzana , Jovanovic Dragana , Rajer Mirjana , Bogos Krisztina , Purkalne Gunta , Ceriman Vesna , Chaudhary Subhash , Richter Igor , Kufa Jirí , Jakubikova Lenka , Zemaitis Marius , Cernovska Marketa , Koubkova Leona , Vilasova Zdenka , Dieckmann Karin , Farkas Attila , Spasic Jelena , Fröhlich Katerina , Tiefenbacher Andreas , Hollosi Virag , Kultan Juraj , Kolarová Iveta , Votruba Jiri 
Published: May 2020

Abstract

Background
Management of non-small-cell lung cancer (NSCLC) is affected by regional specificities. The present study aimed at determining diagnostic and therapeutic procedures including outcome of patients with NSCLC stage III in the real-world setting in Central European countries to define areas for improvements
.

Patients and methods
This multicentre, prospective and non-interventional study collected data of patients with NSCLC stage III in a web-based registry and analysed them centrally.

Results
Between March 2014 and March 2017, patients (n=583) with the following characteristics were entered: 32% females, 7% never-smokers; ECOG performance status (PS) 0, 1, 2 and 3 in 25%, 58%, 12% and 5%, respectively; 21% prior weight loss; 53% squamous carcinoma, 38% adenocarcinoma; 10% EGFR mutations. Staging procedures included chest X-ray (97% of patients), chest CT (96%), PET-CT (27%), brain imaging (20%), bronchoscopy (89%), endobronchial ultrasound (EBUS) (13%) and CT-guided biopsy (9%). Stages IIIA/IIIB were diagnosed in 55%/45% of patients, respectively. N2/N3 nodes were diagnosed in 60%/23% and pathologically confirmed in 29% of patients. Most patients (56%) were treated by combined modalities. Surgery plus chemotherapy was administered to 20%, definitive chemoradiotherapy to 34%, chemotherapy only to 26%, radiotherapy only to 12% and best supportive care (BSC) to 5% of patients. Median survival and progression-free survival times were 16.8 (15.3;18.5) and 11.2 (10.2;12.2) months, respectively. Stage IIIA, female gender, no weight loss, pathological mediastinal lymph node verification, surgery and combined modality therapy were associated with longer survival.

Conclusions
The real-world study demonstrated a broad heterogeneity in the management o f stage III NSCLC in Central European countries and suggested to increase the rates of PET-CT imaging, brain imaging and invasive mediastinal staging.
Major and ancillary features according to LI-RADS in the assessment of combined hepatocellular-cholangiocarcinoma
Authors: Granata Vincenza , Fusco Roberta , Venanzio Setola Sergio , Sandomenico Fabio , Luisa Barretta Maria , Belli Andrea , Palaia Raffaele , Tatangelo Fabiana , Grassi Roberta , Izzo Francesco , Petrillo Antonella 
Published: May 2020

Abstract

Background
The aim of the study was to investigate the performance of the Liver Imaging Reporting and Data System (LI-RADS) v2018 for combined hepatocellular-cholangiocarcinoma (cHCC-CCA) identifying the features that allow an accurate characterization.

Patients and methods
Sixty-two patients (median age, 63 years; range, 38–80 years), with pre-surgical biopsy diagnosis of hepatocellular carcinoma (HCC) that underwent hepatic resection, comprised our retrospective study. All patients were subject to multidetector computed tomography (MDCT); 23 patients underwent to magnetic resonance (MR) study. The radiologist reported the presence of the HCC by using LIRADS v2018 assessing major and ancillary features.

Results
Final histological diagnosis was HCC for 51 patients and cHCC-CCA for 11 patients. The median nodule size was 46.0 mm (range 10–190 mm). For cHCC-CCA the median size was 33.5 mm (range 20–80 mm), for true HCC the median size was 47.5 mm (range 10–190 mm). According to LIRADS categories: 54 (87.1%) nodules as defined as LR-5, 1 (1.6%) as LR-3, and 7 (11.3%) as LR-M. Thirty-nine nodules (63%) showed hyper-enhancement in arterial phase; among them 4 were cHCC-CCA (36.4% of cHCC-CCA) and 35 (68.6%) true HCC. Forty-three nodules (69.3%) showed washout appearance; 6 cHCC-CCAs (54.5% of cHCC-CCA) and 37 true HCC (72.5%) had this feature. Only two cHCC-CCA patients (18.2% of cHCC-CCA) showed capsule appearance. Five cHCC-CCA (71.4% of cHCC-CCA) showed hyperintensity on T2-W sequences while two (28.6%) showed inhomogeneous signal in T2-W. All cHCC-CCA showed restricted diffusion. Seven cHCC-CCA patients showed a progressive contrast enhancement and satellite nodules.

Conclusions
The presence of satellite nodules, hyperintense signal on T2-W, restricted diffusion, the absence of capsule appearance in nodule that shows peripheral and progressive contrast enhancement are suggestive features of cHCC-CCA.
PERFORMA REPRODUKSI IKAN BETOK (Anabas testudineus) BETINA DENGAN PEMBERIAN PAKAN BUATAN BERBAHAN BAKU TEPUNG KEONG MAS (Pomacea canaliculata)
Authors: Ma'ruf Muhammad masrur 
Published: May 2020

Abstrak: Ikan betok (Anabas testudineus) merupakan salah satu spesies ikan lokal yang potensial untuk dibudidayakan. Tujuan penelitian ini untuk mengkaji dan mengevaluasi pengaruh pemberian pakan berbahan baku keong mas (Pomacea canaliculata) terhadap tingkat kematangan gonad. Penelitian dilakukan pada bulan Juli – Agustus 2018. Ikan betok (A. testudineus) berasal dari tangkapan alam di perairan persawahan desa Rias Kecamatan Toboali Kabupaten Bangka Selatan. Ikan betok yang digunakan sebanyak 150 ekor dengan bobot 2 ± 10 gram. Perlakuan yang diberikan pakan buatan yang berbahan baku keong mas (P. canaliculata) dengan kandungan protein pada pakan 32%, 34%, 36%, 38% dan kontrol menggunakan pakan komersil dengan kandungan protein 31 – 33%. Hasil penelitian menunjukkan nilai Indeks Kematangan Gonad (IKG) dengan bobot gonad pada awal penelitian sebesar 0,5 gram. Setelah dilakukan perlakuan dengan pemberian pakan buatan berbahan baku tepung keong mas (P. canaliculata), hasil uji statistik menunjukkan bawa kontrol berbeda nyata dengan perlakuan pada pengamatan GSI dengan kisaran nilai 16% ± 0.02 pada perlakuan P.38%, HSI dengan kisaran nilai 8% ± 0.01 pada perlakuan P.38%. Fekunditas ikan betok (A. testudineus) yang didapatkan pada hasil penelitian dengan kisaran 509 - 4.686 butir. Perkembangan tingkat kematangan gonad (TKG) awal penelitian (TKG II) setelah diberi pakan buatan berbahan baku keong mas (P. canaliculata) meningkat dengan tingkat kematangan gonad mencapai tahap IV.
Kata Kunci : Ikan betok, keong mas, pematangan gonad, IKG, fekunditas, TKG.
EFFECT OF NUTRISIL AND KW21+SI FERTILIZER ON Chaetoceros calcitrans GROWTH
Authors: Lestari Ulan Ayudia , Mukhlis Alis , Priyono Joko 
Published: May 2020

The availability of natural food that meets the needs can improve the quality and quantity of seeds and ensure the sustainability of seeds production produced. One of the most important natural feeds in aquatic ecosystems is phytoplankton which is the main producer that contributes the most to the total primary water products. One type of phytoplankton commonly cultivated is Chaetoceros calcitrans. Nutrient enrichment in growing media can be done through the provision of several types of fertilizers. One type of fertilizer commonly used in phytoplankton cultivation is KW21 fertilizer. Silicate is an essential macro nutrient needed for microalgae growth in the formation of its cell walls to have high resistance to environmental stresses such as extreme conditions. One type of fertilizer that contains silicates which is a fertilizer for local products (Lombok) namely Nutrisil. The aim of the study was to determine the effect of Nutrisil fertilizer and KW21+S on growth and double time of Chaetoceros calcitrans. This study uses a completely randomized design with treatment A= concentration of Nutrisil 1,0 mL/L, B= concentration of Nutrisil 0,75 mL/L, C = concentration of Nutrisil 0,5 mL/L, D = concentration of Nutrisil 0,25 mL/L dan E = concentration of KW21 1 mL/L + Si 1 mg/L. .The data obtained were analyzed using Anova with level 5%. The results showed that the administration of Nutrisil and KW21+Si fertilizer had a significant effect on the growth of Chaetoceros calcitrans.
PENGARUH KOMBINASI HASIL FERMENTASI AMPAS TAHU DAN DEDAK TERHADAP PERTUMBUHAN POPULASI Daphnia sp.
Authors: Zakiyah Fuji , Diniarti Nanda , Dwi Hari Setyono Bagus 
Published: May 2020

Daphnia magna adalah hewan Crustacea yang sering disebut dengan kutu air berukuran kecil yang hidup di perairan tawar dan merupakan salah satu pakan alami untuk larva ikan air yaitu mudah dicerna, ukurannya sesuai dengan bukaan mulut, memiliki kandungan nutrisi yang tinggi, memiliki kandungan asam amino esensial yang tinggi dan dapat dibudidayakan secara massal. Bahan organik ampas tahu dan dedak yang difermentasi dengan bakteri probiotik diharapkan dapat meningkatkan efisiensi pemanfaatan pakan dan pertumbuhan Daphnia magna. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi hasil fermentasi ampas tahu dan dedak terhadap populasi dan menentukan kombinasi pakan terbaik dengan hasil fermentasi ampas tahu dan dedak yang menghasilkan pertumbuhan Daphnia magna yang tinggi. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan dan 3 kali ulangan sehingga memperoleh 12 unit percobaan. Perlakuan A : kontrol (pemberian pakan komersil), perlakuan B (pemberian 0,15 g/l ampas tahu dan 0,3 gl dedak), perlakuan C (pemberian 0,3 g/l ampas tahu), dan perlakuan D (pemberian 0,6 g/l dedak). Hasil penelitian ini menunjukkan bahwa pemberian bahan organik ampas tahu dan dedak melalui proses fermentasi probiotik berpengaruh terhadap kepadatan populasi, laju pertumbuhan populasi, dan produksi biomassa Daphnia magna. Perlakuan B merupakan perlakuan paling baik yaitu dengan kepadatan populasi tertinggi sebesar 246,67 ind/l, laju pertumbuhan populasi sebesar 5,199 %/hari, dan produksi biomassa sebesar 340 mg/l.
La memoria histórica: Camino de reconocimiento de la alteridad en el conflicto armado colombiano
Authors: Rojas Claros Armando , Gómez Quitián Juan Carlos 
Published: May 2020

El presente informe de investigación muestra cómo la memoria histórica puede convertirse en un camino educativo para el fortalecimiento de la alteridad en los estudiantes del curso de lógica y psicología de la Universidad Católica de Colombia, quienes han sido víctimas o espectadores del conflicto armado colombiano. Los participantes del estudio fueron los estudiantes de primer semestre de psicología, pertenecientes a la Universidad Católica de Colombia, de la asignatura Psicología y lógica; dos de los alumnos fueron víctimas directas, los demás han sido espectadores del conflicto armado colombiano. La información obtenida se sometió a un análisis de contenido de acuerdo con las categorías deductivas: alteridad, conflicto armado y memoria histórica.
Los resultados presentan la invisibilización de la persona, ya que han sido víctimas del impacto dentro del conflicto armado colombiano, con unas características propias del conflicto, el olvido y el silencio en contra de la misma humanidad por medio de la violencia que ha deshumanizado y desvirtualizado al ser, llegando a ser calificados como aquellos que son Nadie.
Por otra parte, la vulneración de los derechos humanos hacia las víctimas, por parte del estado y los grupos armados al margen de la ley, es indispensable para la memoria histórica como proceso educativo que lleva al reconocimiento de las personas, como miembros activos de la sociedad.
Ultrasound follow-up of adhesions after one-step laparoscopic abomasopexy for correction of left displaced abomasum in cattle
Authors: CECEN AYALP Goksen , ALTUĞ ŞEN İsmail , GÜL SATAR Nihal Yaşar , TOKOĞLU SERT Sibel 
Published: May 2020

The objective of this study was to
evaluate the use of the ultrasound on the determination of the thickness of
adhesion at the abomasopexy point in cows which had undergone one-step
laparoscopic abomasopexy. Ten Holstein cattle with left displaced abomasum
(LDA) were included in the study. Animals were treated with one-step
laparoscopic abomasopexy whilst standing. Postoperative ultrasonographic
examinations were carried out starting immediately after surgery (day 0), and on
days 28, 90 and 120 by using a 5 MHz transducer frequency and also a linear
transducer. The thickness of the adhesion was measured between the abdominal
wall and the abomasum. Ultrasonographic image revealed the area of fixation on
day 0 as a mild distorted subcutaneous tissue. Heterogeneous hypo-echoic
irregular-shaped mass (adhesion) was observed between the abomasum and
abdominal wall on days 28, 90 and 120. Average thickness significantly (p
&lt;0.05) increased from day 0 to day 28, but tended to decrease afterwards. The
average thickness of adhesion at the abomasopexy point was recorded as 20.47,
22.82, 22.34 and 21.92 mm on days on 0, 28, 90 and 120, respectively.

The
ultrasonographic examination can diagnose and measure the adhesions between the
abomasum and the abdominal wall. During the study period, the adhesion
formation was followed up to the 120th day, and in this period the
thickness of the adhesion tended to decrease. Long follow-up studies are
thought to be beneficial to determine the difference in adhesion thickness.
Антитромботическая активность нового производного диазепино[1,2-<i>a</i>]бензимидазола на модели тромбоза легочной артерии у мышей
Authors: Спасов А. А. , Кучерявенко Аида Фатиховна , Смирнов А. В. , Сиротенко В. С. , Паньшин Н. Г. , Гайдукова К. А. , Диваева Л. Н. 
Published: May 2020

Исследована антитромботическая активность нового химического соединения производного диазепино[1,2-а]бензимидазола под шифром ДАБ-15, проявляющего высокую антиагрегантную активность in vitro и ex vivo. На модели генерализованного адреналин-коллагенового тромбоза было установлено, что исследуемое вещество обладает выраженным антитромбогенным эффектом и превосходит референтные препараты ацетилсалициловую кислоту и клопидогрел.
Pengembangan Bahan Ajar Trigonometri Berbasis Kearifan Lokal
Authors: Nurafni Atika , Pujiastuti Heni , Mutaqin Anwar 
Published: May 2020

Tujuan penalitian ini adalah menghasilkan bahan ajar matematika melalui pendekatan kearifan lokal pada materi trigonometri yang layak dan sesuai kebutuhan siswa. Jenis penelitian ini adalah Penelitian dan Pengembangan (R&D) dengan menggunakan model ADDIE yang terdiri dari lima tahap, yaitu analyze (analisis), design (perancangan), development (pengembangan), implement (implementasi) dan evaluate (evaluasi). Instrumen yang digunakan yaitu lembar angket validasi ahli materi dan ahli media, angket respon guru matematika, dan angket respon siswa. Berdasarkan penelitian diperoleh hasil validasi ahli dengan persentase 80% (layak), respon guru dengan persentase 79% (baik) dan respon siswa dengan persentase 78% (baik). Secara keseluruhan bahan ajar ini dapat di terima dengan baik oleh guru dan siswa didukung oleh hasil validasi dari para ahli yang menyatakan bahan ajar layak digunakan untuk kegiatan belajar.
Kata kunci: bahan ajar, trigonometri, kearifan lokal
ABSTRACT
The purpose of this research is to produce mathematics teaching materials through a local wisdom approach to trigonometry material that is appropriate and in accordance with the needs of students. This type of research is Research and Development (R&D) using the ADDIE model which consists of five stages, that is analyze, design, development, implement and evaluate. The instrument used were questionnaire validation sheet material experts and media expert, mathematics teacher response questionnaire and student response questionnaire. Based on the research results obtained by expert validation with a percentage of 80% (feasible), teacher response with a percentage of 79% (good) and responses students with a percentage of 78% (good0. Overall this teaching material can be well received by teachers and studens, supported by validation results from experts who claim teaching materials are suitable for use in learning activities.
Keywords: teaching materials, trigonometry, local wisdom
Properties Of An Analogue Cheese Obtained From Raw Peanut
Authors: Eudier H. , Ben-Harb S. , Lorand J.P. , Duthil F. , Negahban M. , Saiter J.M. , Chan-Huot M. 
Published: May 2020

ABSTRACT
The focus is on a peanut suspension in which starch is added and that exhibits specific mechanical characteristics relevant for food products. The mixture is composed of water, lipids, starch, and proteins. The process consists of blending together the different constituents, and the study changes the experimental conditions to tune the mechanical behavior of the mixture. The rheological properties (viscosity, indentation) and physical parameters such as color, dry extract, and particle size distribution were measured. The matrix behavior was studied after a centrifugation step necessary to determine stability of the emulsion, and for varying shearing durations. Short shearing duration induce a maximum of firmness, observed by measuring indentation resistance, and a maximum of spreadability, evaluated by shear rheometry. On the contrary, long shearing durations destabilize the matrix emulsion by increasing the oil separation capacity. This study observes structural changes in the rheological behavior of this analogue artificial cheese that correlates with the extent of shearing.
Rainout Shelter-Induced Water Deficit Negatively Impacts Peanut Yield and Quality in a Sub-Humid Environment
Authors: Balota M. 
Published: May 2020

ABSTRACT
Water deficit significantly reduces yield potential of peanut (Arachis hypogaea L.) worldwide. Availability of drought tolerant cultivars is essential, but their selection is difficult, in particular in environments where rainfall is unpredictable. This study investigated the response of eleven peanut genotypes to three water regimes and was aimed to determine if use of rainout shelters is a reliable selection method for drought tolerance in a sub-humid environment with unpredictable rainfall pattern. Water regimes were achieved by covering the plots from mid-July to early Sep with the rainout shelters and irrigating the plots to pre-determined levels: well-watered (WW) regime received full irrigation of 40 mm weekly, moderate deficit (MD) 17 mm weekly, and severe deficit (SD) only 40 mm in one “survival” irrigation in late Aug. Results showed that MD and SD reduced yield and grade for all genotypes. Compared with WW, economic value of all genotypes was 24% less under MD and 68% less under SD. Small seeded runner cultivars, ‘Florida 07′ and ‘Georgia 06G', had higher yield and grade than Virginia-type cultivars under deficit irrigation, in particular under SD. Among the Virginia-type, ‘Sugg' had highest yields under SD but was out yielded by ‘Bailey' and ‘Phillips' under MD. ‘Wynne' and ‘Spain' are the largest seeded Virginia-type cultivars; they performed poorest for yield and grade. The relative proportion of oleic fatty acid (C18:1) was less under SD compared to WW; and linoleic fatty acid (C18:2) and total saturated oils were more, but intensities depended on the genotype. Finally, the rainout setting provided comparative results with real farm peanut production in the region; this is important for breeding programs in Virginia and Carolinas, where rainfall unpredictability does not allow for drought screening in an open field setting.