bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leaf litter quality drives the feeding by invertebrate shredders in tropical streams
Authors: Sena Guilherme , Francisco Gonçalves Júnior José , Tavares Martins Renato , Hamada Neusa , de Souza Rezende Renan 
Published: July 2020

AbstractAmazon and Cerrado‐forested streams show natural fluctuations in leaf litter quantity along the time and space, suggesting a change on litter quality input. These natural fluctuations of leaf litter have repercussion on the organic matter cycling and consequently effects on leaf decomposition in forested streams. The effects of the quantity of leaf litter with contrasting traits on consumption by larvae of shredder insects from biomes with different organic matter dynamics have still been an understudied question. The TrichopteraPhylloicusspp. is a typical shredder in tropical headwater streams and keep an important role in leaf litter decomposition. Here, we assessed the consumption by shredderPhylloicusspp., from Amazonia and Cerrado biomes, on higher (Maprounea guianensis) and lower quality leaves (Inga laurina) in different proportions and quantities. Experiments were performed concomitantly in microcosms approaches, simulating Cerrado and Amazonian streams. Higher leaf consumption occurred in Cerrado microcosms. Litter quantity influenced negatively leaf consumption by shredders in Cerrado, in opposition to Amazonia, where consumption was not affected by leaf quantity. In both sites, we observed higher consumption by shredders in treatment with onlyM. guianensisand no difference between other treatments with mixture of leaves. In treatment with litter ofI. laurina,we noted the use of substrate for case building (due to the higher leaf toughness),affecting the fragmentation process. Therefore, our results indicate that leaf litter quality drives the preference of consumption byPhylloicuslarvae in Cerrado and Amazonia streams.
Hydrothermally Synthesized MoS2 Nanoclusters for Hydrogen Evolution Reaction
Authors: Mishra Shanu , Mishra Ashish Kumar 
Published: July 2020

AbstractAs an alternative to noble metals, MoS2 has been recognized as promising active and earth abundant electrocatalyst for the hydrogen evolution reaction (HER). Here, we demonstrate novel 2H‐phase MoS2 nanoclusters as efficient electrocatalyst for HER, prepared via hydrothermal process without using additional reducing agents to precursors. The MoS2 nanoclusters coated carbon paper electrode shows Tafel slope of 103 mV dec−1 at voltage sweep rate of 2 mV s−1 for HER with onset potential and over‐potential (η10) of 0.132 and 0.212 V, respectively. The good catalytic performance can be attributed to large accessible electrochemically active surface area and sites along with easy transport of electrolyte due to hydrophilic nature of prepared MoS2 nanoclusters.
A Batch Injection Analysis System with Square‐wave Voltammetric Detection for Fast and Simultaneous Determination of Zinc and Ascorbic Acid
Authors: Ribeiro Michelle M. A. C. , Rocha Raquel G. , Munoz Rodrigo A. A. , Richter Eduardo M. 
Published: July 2020

AbstractThe determination of organic and inorganic compounds in a single run is still a great challenge. In this paper, we developed a method for fast simultaneous determination of ascorbic acid (AA) and zinc ions (Zn) using batch injection analysis with detection by square‐wave anodic stripping voltammetry (BIA‐SWASV). Britton‐Robinson (BR) buffer solution (pH=6.0) as the supporting electrolyte and boron doped diamond (BDD) as the working electrode. The method presented favorable analytical characteristics such as fast response (67 injections h−1), low detection limits (0.2 and 5.4 μmol L−1for Zn ions and AA, respectively) and recovery values of 99±3%.
Paper‐based Potentiometric Biosensor for Monitoring Galactose in Whole Blood
Authors: Bouri Mohamed , Zuaznabar‐Gardona Julio C. , Novell Marta , Blondeau Pascal , Andrade Francisco J. 
Published: July 2020

AbstractA filter paper sputtered with a layer of Pt and subsequently coated with a Nafion® membrane is used as working electrode. The mixed potential of the Pt electrode allows the detection of H2O2 generated by the oxidation of galactose in the presence of the galactose oxidase enzyme. This provides a simple and mediator‐free approach method. The system shows sensitivity values of −62.8±9.4 mV/decade of galactose in the range from 0.3 to 31.6 mM, well within the clinical relevant range. MnO2 nanoparticles were added to decrease the interference from ascorbic acid so that validation of the sensor in whole blood samples was performed with good recovery.
Fe2O3/MCM‐41 as catalysts for methyl orange degradation by Fenton‐like reactions
Authors: Sidney Santana Cássia , Freire Bonfim Daniela Patrícia , da Cruz Ivana Helena , da Silva Batista Marcelo , Fabiano Demian Patrick 
Published: July 2020

AbstractA large amount of contaminated industrial wastewater has aroused mounting concern by researchers and environmentalists. Dyes contained in industrial effluents are often quite persistent to biodegradation, which must be treated before being disposed of. In this context, the use of Fenton processes is a potential alternative to treat a wide range of dyes and other organic pollutants found in wastewater. Thus, several Fe2O3/MCM‐41 catalysts have been synthesized in the following molar ratio of SiO2/Fe2O3: 10, 20, 40, 100, and 200. They were characterized by N2adsorption–desorption isotherm, X‐ray fluorescence (XRF), X‐ray diffraction (XRD), UV–vis spectroscopy and H2temperature‐programmed reduction (H2‐TPR), and applied to degrade methyl orange dye (MO) via a heterogeneous Fenton reaction. Catalytic tests revealed that SiO2/Fe2O3= 10 reached the highest activity due to greater availability of active sites which generated a larger quantity of hydroxyl (•OH) and perhydroxyl (•OOH) radicals. Furthermore, 70% of color removal has been achieved after 120 min at room temperature. Moreover, the systems moderately enhanced organic matter mineralization according to chemical oxygen demand (COD) testing. There was also catalytic activity loss in consecutive reaction cycles, which is probably due to dye molecules adsorption on active sites.
Inflexible silicon solar cell encapsulation process on curved surfaces: Experimental investigation
Authors: Kassaei Farshid , Rafiei Reza , Torabi Farschad 
Published: July 2020

AbstractThe process of encapsulating solar cells on curved surfaces is one of the most challenging subjects today and has been widely studied. In most studies, thin‐film and flexible cells have been chosen for curved surfaces. In this article, a new method is proposed to carry out the process of encapsulating a solar cell on the curved surfaces using inflexible silicon solar cell. In this method, transparent epoxy resin is injected into the solar cell area using an embedded mold. Once the resin is cured and the mold is removed, the obtained surface forms the desired curved shape. This method can be used for fixed curved surfaces that are not exposed to tension. The method was performed on a sectional sample of a wind turbine blade which resulted in a curved and transparent layer on the cells. Then the section was tested under the environmental condition and exposed to direct sunlight. The results showed a normal performance of the cell with high efficiency and a maximum error rate of 8% compared to the laboratory report of the manufacturer. Voltage and current of the cell were normal in this experiment. The I–V curve diagram showed the standard behavior of cells as well. The maximum power output from the section was 1.308 W. Results showed that this method is suitable for solid curved surfaces to be used as a photovoltaic module.
The relation between two barriers to self‐compassion and clinical characteristics in individuals with eating disorders
Authors: Geller Josie , Kelly Allison C. , Samson Lindsay , Iyar Megumi M. , Srikameswaran Suja 
Published: July 2020

AbstractThere is growing support for the role of self‐compassion in recovery from an eating disorder (ED) and two types of barriers have been identified in this population: (a) fears that self‐compassion will result in a failure to meet personal and interpersonal standards (meeting standards); and (b) fears that self‐compassion gives rise to difficult emotions such as grief and unworthiness (emotional vulnerability).ObjectiveThis research examined the relative contribution of meeting standards and emotional vulnerability barriers to the clinical characteristics of individuals with EDs.MethodParticipants (N = 349) completed the fears of compassion for self‐scale, and measures of self‐compassion, ED and psychiatric symptom severity, interpersonal and affective functioning, quality of life and readiness for ED change.ResultsTogether, the two barrier types accounted for significant variance in all study variables. Meeting standards was associated with lower readiness to change and greater over‐control. In contrast, emotional vulnerability was associated with lower self‐compassion, readiness, and quality of life, poorer interpersonal and affective functioning, and greater ED and psychiatric severity.ConclusionWhile both barriers to self‐compassion were related to functioning in individuals with EDs, the emotional vulnerability barrier accounted for more variance in pathology and may be most beneficial to target in treatment.
Phagocytosis‐related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
Authors: Shahraz Anahita , Wißfeld Jannis , Ginolhac Aurélien , Mathews Mona , Sinkkonen Lasse , Neumann Harald 
Published: July 2020

AbstractRepeated systemic challenge with lipopolysaccharides (LPS) can induce microglia activation and inflammatory neurodegeneration in the substantia nigra pars compacta region of mice. We now explored the role of mononuclear phagocytes associated nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX‐2) in inflammatory neurodegeneration. Cybb‐deficient NOX‐2 knock‐out (KO) and control wild type (WT) mice were treated intraperitoneally daily over four consecutive days with 1 μg/gbw/day LPS. Transcriptome analysis by RNA‐seq of total brain tissue indicated increased LPS‐induced upregulation of genes belonging to the reactive oxygen species and reactive nitrogen species production, complement and lysosome activation as well as apoptosis and necroptosis in WT compared to NOX‐2 KO mice. Validation of up‐regulated gene transcripts via qRT‐PCR confirmed that LPS‐challenged NOX‐2 KO mice expressed lower levels of the microglial phagocytosis‐related genes Nos2, Cd68, Aif1/Iba1, Cyba, Itgam, and Fcer1g compared to WT mice at Day 5 after systemic inflammatory challenge, but no significant differences in the pro‐inflammatory genes Tnfα and Il1b as well as microglial IBA1 and CD68 intensities were observed between both genotypes. Furthermore, loss of tyrosine hydroxylase positive (TH+) and NeuN positive neurons in the substantia nigra pars compacta upon repeated systemic LPS application were attenuated in NOX‐2 KO mice. Thus, our data demonstrate that loss of dopaminergic neurons in the substantia nigra pars compacta after repeated systemic challenge with LPS is associated with a microglial phagocytosis‐related gene activation profile involving the NADPH oxidase subunit Cybb/gp91phox.
Global, regional, and national burden of nasopharyngeal carcinoma from 1990 to 2017—Results from the Global Burden of Disease Study 2017
Authors: Hu Chuan‐Yu , Wang Wei‐Ming , Chu Xiu‐Hong , Ren Zhen‐Hu , Lyu Jun 
Published: July 2020

AbstractBackgroundThe aim of this study is to estimate the incidence, mortality, and disability‐adjusted life years (DALYs) of nasopharyngeal carcinoma from 1990 to 2017.MethodsWe collected detailed information on nasopharyngeal carcinoma from 1990 to 2017 based on data from Global Burden of Disease (GBD) study 2017. The global incidence, mortality, and DALYs attributable to nasopharyngeal carcinoma was reported, as well as the age‐standardized rates (ASRs).ResultsThe ASR of nasopharyngeal carcinoma incidence decreased from 1.88 (95% UI: 1.76‐2.00) in 1990 to 1.35 (95% UI: 1.28‐1.42) in 2017. The ASR of mortality decreased from 1.19 (95% UI: 1.13‐1.25) in 1990 to 0.86 (95% UI: 0.82‐0.89) in 2017, while ASR‐DALYs decreased from 38.2 (95% UI: 35.9‐40.2) in 1990 to 25.4 (95% UI: 24.4‐26.5) in 2017.ConclusionsThe ASR of incidence, mortality, and DALYs of nasopharyngeal carcinoma have decreased slightly worldwide. East Asia carried the heaviest burden of nasopharyngeal carcinoma. The majority of nasopharyngeal carcinoma burden was observed in men, especially among male aged 55 to 69 years.
Perceived managerial and leadership effectiveness within the Canadian public sector
Authors: Hamlin Robert G. , Whitford Sandi 
Published: July 2020

AbstractThis study responds primarily to numerous calls for specific public management and public administration‐related research to better understand public leadership currently performed in an increasingly complex and ambiguous world. It also responds to calls in the human resource development (HRD) literature for more qualitative managerial behavior research. The inquiry explores perceptions of what behaviorally distinguishes effective managers from ineffective managers, as expressed by managers and nonmanagerial employees within a Canadian public utility company. It reaches for generalization by comparing the results against findings from equivalent qualitative managerial behavior studies carried out in three subareas of the British public sector. Using the critical incident technique (CIT), concrete examples (critical incidents [CIs]) of observed managerial behavior were collected from managers and nonmanagerial staff. The CIs (n= 530) were subjected toopenandaxialcoding to identify a smaller number of discrete behavioral categories (BSs).Selectivecoding of the identified BSs (n= 99) resulted in 16 positive (effective) and 12 negative (ineffective) behavioral criteria (BCs) being deduced. Over 92% of the Canadian BSs are convergent in meaning with over 81% of the compared British BSs. Consequently, they are likely to be generalizable to other subareas of the Canadian public sector. The 8% of nonconvergent Canadian BSs and their respective underpinning CIs contain no content that could be construed as beingcontext‐specificto the Canadian public utility sector. Implications of these study findings for HRD research and practice are discussed.
Chronic lymphocytic leukemia patients withIGHtranslocations are characterized by a distinct genetic landscape with prognostic implications
Authors: Pérez‐Carretero Claudia , Hernández‐Sánchez María , González Teresa , Quijada‐Álamo Miguel , Martín‐Izquierdo Marta , Hernández‐Sánchez Jesús‐María , Vidal María‐Jesús , de Coca Alfonso García , Aguilar Carlos , Vargas‐Pabón Manuel , Alonso Sara , Sierra Magdalena , Rubio‐Martínez Araceli , Dávila Julio , Díaz‐Valdés José R. , Queizán José‐Antonio , Hernández‐Rivas José‐Ángel , Benito Rocío , Rodríguez‐Vicente Ana E. , Hernández‐Rivas Jesús‐María 
Published: July 2020

AbstractChromosome 14q32 rearrangements/translocations involving the immunoglobulin heavy chain (IGH) are rarely detected in chronic lymphocytic leukemia (CLL). The prognostic significance of theIGHtranslocation is controversial and its mutational profile remains unknown. Here, we present for the first time a comprehensive next‐generation sequencing (NGS) analysis of 46 CLL patients withIGHrearrangement (IGHR‐CLLs) and we demonstrate that IGHR‐CLLs have a distinct mutational profile with recurrent mutations inNOTCH1,IGLL5,POT1,BCL2,FBXW7,ZMYM3,MGA,BRAFandHIST1H1Egenes. Interestingly,BCL2andFBXW7mutations were significantly associated with this subgroup and almost half ofBCL2,IGLL5andHISTH1Emutations reported were previously identified in non‐Hodgkin lymphomas. Notably,IGH/BCL2rearrangements were associated with a lower mutation frequency and carriedBCL2andIGLL5mutations, while the other IGHR‐CLLs had mutations in genes related to poor prognosis (NOTCH1,SF3B1andTP53) and shorter time to first treatment (TFT). Moreover, IGHR‐CLLs patients showed a shorter TFT than CLL patients carrying 13q−, normal fluorescence in situ hybridization (FISH) and +12 CLL, being this prognosis particularly poor whenNOTCH1,SF3B1,TP53,BIRC3andBRAFwere also mutated. The presence of these mutations not only was an independent risk factor within IGHR‐CLLs, but also refined the prognosis of low‐risk cytogenetic patients (13q−/normal FISH). Hence, our study demonstrates that IGHR‐CLLs have a distinct mutational profile from the majority of CLLs and highlights the relevance of incorporating NGS and the status ofIGHby FISH analysis to refine the risk‐stratification CLL model.
Intertemporal price discovery between stock index futures and spot markets: New evidence from high‐frequency data
Authors: Sifat Imtiaz Mohammad , Mohamad Azhar , Amin Kevin Reinaldo 
Published: July 2020

AbstractThis article utilizes high‐frequency 15‐s intraday data from September 2017 through to August 2018 to investigate price leadership dynamics between Kuala Lumpur index futures (FKLI) and its underlying spot market: FTSE Bursa Malaysia Kuala Lumpur Composite Index (FBM KLCI) in Bursa Malaysia. Harnessing the explanatory powers of Wavelet analysis, we employ Maximal Overlap Discrete Wavelet Transform to evaluate interdependence between contemporaneous futures and spot returns. We observe that price discovery between futures and spot markets at granular level is a scale‐dependent phenomenon. Moreover, we record a counter‐intuitive but not unprecedented evidence of futures market lagging the spot market in price formation. This discrepancy approaches convergence in 1–8 min. Our findings constitute evidence against the efficient market hypothesis and hint at opportunities for statistical arbitrage by high‐frequency trading. The results from time‐frequency domain receive strong support from vector error correction robustness checks, though corroboration is less conclusive from DCC‐GARCH and Baba, Engle, Kraft, and Kroner‐GARCH results.
Military expenditure, financial development and environmental degradation in Turkey: A comparison of CO2 emissions and ecological footprint
Authors: Gokmenoglu Korhan K. , Taspinar Nigar , Rahman Mohammad Mafizur 
Published: July 2020

AbstractThis study investigates the long run equilibrium relationship among military expenditure, financial development, energy use, economic growth and environmental degradation in Turkey for the period of 1960–2014. Ecological footprint and carbon dioxide emissions are used as separate proxies for environmental degradation. Fully modified ordinary least squares (FMOLS) estimator results suggest that military expenditure, energy use and economic growth increase the environmental degradation while financial development improves the environmental quality in Turkey. Toda Yamamoto (1995) causality test results reveal that there is a unidirectional causality running from military expenditure to CO2 emissions and ecological footprint; and a bidirectional causality between military expenditure and economic growth. The findings of the study confirm the existence of destruction theory for the case of Turkey.
Economic impact of monetary policy: Focus on real estate sector in Italy
Authors: Ahmed Irfan , Socci Claudio , Medabesh Ali , Severini Francesca , Zotti Jacopo 
Published: July 2020

AbstractThis study investigates the nexus between financial market and real estate (RE) sector against the backdrop of ECB's unconventional monetary policy. A financial dynamic computable general equilibrium (DCGE) model is calibrated on the financial social accounting matrix (FSAM) of Italian economy. The findings confirm that the inclusion of financial intermediation into real economy affects the real estate sector's output, value added, and pricing.
Ubiquilin proteins regulate EGFR levels and activity in lung adenocarcinoma cells
Authors: Kurlawala Zimple , Saurabh Kumar , Dunaway Rain , Shah Parag P. , Siskind Leah J. , Beverly Levi J. 
Published: July 2020

AbstractUbiquilin (UBQLN) proteins are involved in diverse cellular processes like endoplasmic reticulum‐associated degradation, autophagy, apoptosis, and epithelial‐to‐mesenchymal transition. UBQLNs interact with a variety of substrates, including cell surface receptors, transcription factor regulators, proteasomal machinery proteins, and transmembrane proteins. In addition, previous work from our lab shows that UBQLN1 interacts with insulin‐like growth factor receptor family members (IGF1R, IGF2R, and INSR) and this interaction regulates the activity and proteostasis of IGFR family members. We wondered whether UBQLN proteins could also bind and regulate additional receptor tyrosine kinases. Thus, we investigated a link between UBQLN and the oncogene epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells. Loss of UBQLN1 occurs at high frequency in human lung cancer patient samples and we have shown that the loss of UBQLN1 is capable of altering processes involved in cell proliferation, migration, invasion, and epithelial‐to‐mesenchymal transition in lung adenocarcinoma cell lines. Here, we present data that loss of UBQLN1 resulted in increased turnover of total EGFR while increasing the relative amount of phosphorylated EGFR in lung adenocarcinoma cells, especially in the presence of its ligand EGF. Furthermore, the loss of UBQLN1 led to a more invasive cell phenotype as manifested by increased proliferation, migration, and speed of movement of these lung adenocarcinoma cells. Taken together, UBQLN1 regulates the expression and stability of EGFR in lung cancer cells.
Synthesis, cytotoxicity and apoptosis‐inducing activity of novel 1H‐benzo[d]imidazole derivatives of dehydroabietic acid
Authors: Li A‐Liang , Yang Ya‐Qun , Wang Wen‐Yan , Liu Qing‐Song , Sun Yue , Gu Wen 
Published: July 2020

AbstractWith the expectation of finding new and effective antitumor drugs, a series of novel N‐(1H‐benzo[d]imidazole‐2‐yl)‐benzamide/benzenesulfonamide derivatives of dehydroabietic acid were synthesized and evaluated for cytotoxic activity against three human cancer cell lines (MCF‐7, HeLa, and HepG2 cells) and one human normal hepatocyte cell line (LO2). As a result, a number of derivatives showed moderate to good antitumor activities. Among them, compound 8h exhibited the most potent activities against three cancer cell lines with IC50 values of 0.87 ± 0.18, 9.39 ± 0.72, and 8.31 ± 0.64 μM, respectively, and was less active to normal hepatocyte LO2 cells. Further mechanism studies revealed that compound 8h could arrest the cell cycle of MCF‐7 cells at S phase and induce the apoptosis of MCF‐7 cells in ROS‐mediated mitochondrial pathway.