bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comportamiento del peso en recién nacidos tratados con nutrición parenteral
Authors: Sánchez-Consuegra Ricardo , Hernández Vanesa , Hernández Ricardo , Montaño-Bandera Julio 
Published: May 2020

Antecedentes La nutrición parenteral es un aporte que debe redituar en la mejoría del crecimiento y desarrollo a corto y largo plazo de los neonatos, en especial de los prematuros. El uso temprano de la nutrición parenteral con los nutrientes en cantidad adecuada debería prevenir la pérdida considerada antes fisiológica del peso de los recién nacidos enfermos.
Objetivo Determinar el comportamiento del peso en neonatos que reciben nutrición parenteral como único aporte nutricional.
Materiales y métodos Estudio descriptivo observacional y prospectivo en 44 neonatos, en su mayor parte prematuros, cuyo único aporte nutricional era la nutrición parenteral vía catéter percutáneo, de ambos sexos, tratados en la unidad de cuidados intensivos de la Clínica General San Diego, de Barranquilla, Colombia. Se obtuvieron datos de sexo, edad gestacional, peso en gramos al inicio y final del uso de la nutrición parenteral, peso diario, días de nutrición parenteral y patologías asociadas. El análisis estadístico incluyó medidas de frecuencias.
Resultados De los 44 recién nacidos incluidos, 43 fueron pretérmino y un recién nacido a término, con principal diagnóstico de prematurez y dificultad respiratoria, además de sepsis y enterocolitis necrosante. El promedio de incremento del peso al final de la nutrición parenteral fue de 5 a 15 gr/kg/día, con diferencias en cuanto a la progresión del peso basal y final.
Conclusiones La utilización de la nutrición parenteral ayuda a promover el incremento de peso en los neonatos cuando se utiliza por más de tres días.
Kandungan beta karoten, polifenol total dan aktifitas ”merantas” radikal bebas kefir susu kacang hijau (Vigna radiata) oleh pengaruh jumlah starter (Lactobacillus bulgaricus dan Candida kefir) dan konsentrasi glukosa
Authors: Supriyono Teguh , Murwani Retno , Nurrahman Nurrahman 
Published: May 2020

Background: Kefir is a well known fermented dairy milk product which is functional for gut health. However kefir can also be made from vegetable milk such as soy or mungbean milk. Objective: To study the chemical and functional property of Mungbean milk (MBM) Kefir Methods:Mungbean milk was fermented into MBM Kefir using Lactobacillus bulgaricus and Candida kefir. Three levels of cultures and glucose concentration were tested and a complete randomized design experiment was employed. The resulting MBM Kefir were tested for β-carotene level, total polyphenol content, and free radical scavenging activity. Beta carotene level, total polyphenols and free radicals scavenging activity were determined by spectrophotometry, Folin-Ciocalteu method, and DPPH radical scavenging assay respectively. The data were analyzed by ANOVA and when the result of ANOVA was significant, Tukey’s multiple comparison was conducted. Results: Culture concentration increased β-carotene level (p = 0.049), total polyphenol (p = 0.015) and free radical scavenging activity (p = 0,000) of MBM kefir. Glucose concentration increased total polyphenol (p = 0.002), but had no effect on free radical scavenging activity and β-carotene level. However, there were no interaction among treatments at 0.05 significance level. Total acid level ranged from 1.57 to 2.54%, with the highest and level at 15% cultures concentration and 15% glucose concentration. Alcohol level ranged from 0.26 to 0.90% which was in accordance with the maximum standard for kefir (1%). Conclusion: An optimal product of mungbean milk kefir with highest free radical scavenging activity can be obtained using 15% cultures (Lactobacillus bulgaricus and Candida kefir) and 10% glucose concentration.
Study of the Behavior of Moisture Absorption and Swelling in High Filler Loading Kenaf Core/Bast Polyethylene Composites
Authors: Aziz Nurul Faiizin Abdul , Ahmad Zakiah , Puaad Muhammad Bazli Faliq Mohd 
Published: May 2020

Abstract
One of the major concerns of wood plastic composite for outdoor application is moisture absorption and thickness swelling (TS). This study investigates the effect of temperature on moisture absorption and TS characteristics of kenaf reinforced polyethylene composite (KPeC). The kenaf materials (core and bast) are at a ratio of 60:10 and were treated with 10 % magnesium chloride (MgCl2). For the preparation of composites, the weight ratio of the kenaf filler (containing core and bast) to high-density polyethylene matrix was 70:22 (wt./wt.), and the weight of the coupling agent in the formulation was 3 wt. %. The composites were prepared using a hot compression molding. The effect of temperature and humidity on the properties of the KPeCs were determined following conditioning at different temperature and relative humidity (RH) combinations, namely 20°C-95%RH, 30°C-95%RH, 50°C-95%RH, and soaking in water at 20°C. The KPeCs were conditioned at various combinations of temperature and RH (20°C-95%RH, 30°C-95%RH, 50°C-95%RH, and soaking in water at 20°C) and the effects of these various conditions on the properties of KPeCs were determined. At 95% RH exposure, the moisture absorption and swelling rate of both composites increased as the temperature increased. All KPeCs at different exposures exhibited Fickian behavior except for KPeCControl and KPeC10%-MgCl2 when aged at 20°C-95%RH.
Effect of Plural Spray Coating Process Parameters on Bonding Strength of Polyurea with Steel and Aluminum for Liquid Storage Applications
Authors: Arunkumar T. , Anand G. , Venkatachalam P. , Anish M. , Jayaprabakar J. , Sajin J. B. 
Published: May 2020

Abstract
The intention of surface coating is to improve the lifespan of the hazardous liquid storage tank to avoid the catastrophic failure by corrosion or leakage. Water or oxygen present inside the storage tanks tends to permeate through the substrate because of the poor adhesive properties, leading to corrosion, leakage, etc. Recently, polyurea (PU) has been widely used as a surface coating to protect the material under various harsh loads and climatic conditions. However, ultimate variation in the efficiency of PU coating is with respect to various coating process parameters. Herein, the plural spray coating process parameters, namely mixing ratio, temperature, coating pressure, and stand-off distance on the bonding strength of PU coating with steel and aluminium, were optimized. Furthermore, with the help of the Taguchi method, the optimum process parameters and their corresponding levels were identified, and it was found that each response has a different best process parameter. To circumvent this, Grey relational analysis (GRA) was carried out, and it has improved the overall efficiency of both the substrates by nearly 10 %.
MECP2Duplication Causes Aberrant GABA Pathways, Circuits and Behaviors in Transgenic Monkeys: Neural Mappings to Patients with Autism
Authors: Cai Dan-Chao , Wang Zhiwei , Bo Tingting , Yan Shengyao , Liu Yilin , Liu Zhaowen , Zeljic Kristina , Chen Xiaoyu , Zhan Yafeng , Xu Xiu , Du Yasong , Wang Yingwei , Cang Jing , Wang Guang-Zhong , Zhang Jie , Sun Qiang , Qiu Zilong , Ge Shengjin , Ye Zheng , Wang Zheng 
Published: May 2020

MECP2gain-of-function and loss-of-function in genetically engineered monkeys recapitulates typical phenotypes in patients with autism, yet whereMECP2mutation affects the monkey brain and whether/how it relates to autism pathology remain unknown. Here we report a combination of gene–circuit–behavior analyses includingMECP2coexpression network, locomotive and cognitive behaviors, and EEG and fMRI findings in 5MECP2overexpressed monkeys (Macaca fascicularis; 3 females) and 20 wild-type monkeys (Macaca fascicularis; 11 females). Whole-genome expression analysis revealedMECP2coexpressed genes significantly enriched in GABA-related signaling pathways, whereby reduced β-synchronization within fronto-parieto-occipital networks was associated with abnormal locomotive behaviors. Meanwhile,MECP2-induced hyperconnectivity in prefrontal and cingulate networks accounted for regressive deficits in reversal learning tasks. Furthermore, we stratified a cohort of 49 patients with autism and 72 healthy controls of 1112 subjects using functional connectivity patterns, and identified dysconnectivity profiles similar to those in monkeys. By establishing a circuit-based construct link between genetically defined models and stratified patients, these results pave new avenues to deconstruct clinical heterogeneity and advance accurate diagnosis in psychiatric disorders.SIGNIFICANCE STATEMENTAutism spectrum disorder (ASD) is a complex disorder with co-occurring symptoms caused by multiple genetic variations and brain circuit abnormalities. To dissect the gene–circuit–behavior causal chain underlying ASD, animal models are established by manipulating causative genes such asMECP2. However, it is unknown whether such models have captured any circuit-level pathology in ASD patients, as demonstrated by human brain imaging studies. Here, we use transgenic macaques to examine the causal effect ofMECP2overexpression on gene coexpression, brain circuits, and behaviors. For the first time, we demonstrate that the circuit abnormalities linked toMECP2and autism-like traits in the monkeys can be mapped to a homogeneous ASD subgroup, thereby offering a new strategy to deconstruct clinical heterogeneity in ASD.
Improving Prediction Accuracy Using Multi-allelic Haplotype Prediction and Training Population Optimization in Wheat
Authors: Sallam Ahmad H , Conley Emily , Prakapenka Dzianis , Da Yang , Anderson James A 
Published: May 2020

Abstract
The use of haplotypes may improve the accuracy of genomic prediction over single SNPs because haplotypes can better capture linkage disequilibrium and genomic similarity in different lines and may capture local high-order allelic interactions. Additionally, prediction accuracy could be improved by portraying population structure in the calibration set. A set of 383 advanced lines and cultivars that represent the diversity of the University of Minnesota wheat breeding program was phenotyped for yield, test weight, and protein content and genotyped using the Illumina 90K SNP Assay. Population structure was confirmed using single SNPs. Haplotype blocks of 5, 10, 15, and 20 adjacent markers were constructed for all chromosomes. A multi-allelic haplotype prediction algorithm was implemented and compared with single SNPs using both k-fold cross validation and stratified sampling optimization. After confirming population structure, the stratified sampling improved the predictive ability compared with k-fold cross validation for yield and protein content, but reduced the predictive ability for test weight. In all cases, haplotype predictions outperformed single SNPs. Haplotypes of 15 adjacent markers showed the best improvement in accuracy for all traits; however, this was more pronounced in yield and protein content. The combined use of haplotypes of 15 adjacent markers and training population optimization significantly improved the predictive ability for yield and protein content by 14.3 (four percentage points) and 16.8% (seven percentage points), respectively, compared with using single SNPs and k-fold cross validation. These results emphasize the effectiveness of using haplotypes in genomic selection to increase genetic gain in self-fertilized crops.
Meta-analysis of Diets Used inDrosophilaMicrobiome Research and Introduction of theDrosophilaDietary Composition Calculator (DDCC)
Authors: Lesperance Danielle N A , Broderick Nichole A 
Published: May 2020

AbstractNutrition is a major factor influencing many aspects of Drosophila melanogaster physiology. However, a wide range of diets, many of which are termed “standard” in the literature, are utilized for D. melanogaster research, leading to inconsistencies in reporting of nutrition-dependent phenotypes across the field. This is especially evident in microbiome studies, as diet has a pivotal role in microbiome composition and resulting host-microbe interactions. Here, we performed a meta-analysis of diets used in fly microbiome research and provide a web-based tool for researchers to determine the nutritional content of diets of interest. While our meta-analysis primarily focuses on microbiome studies, our goal in developing these resources is to aid the broader community in contextualizing past and future studies across the scope of D. melanogaster research to better understand how individual lab diets can contribute to observed phenotypes.
Nutritional contents in <i>Myrciaria dubia</i> plants in function of in Potassium doses applied through fertigation
Authors: Abanto-Rodríguez Carlos , Alves Chagas Edvan , Farias Araújo Wellintong , Lopes Monteiro Neto João Luiz , Medeiros de Oliveira Eduardo , Gonçalves Paulichi Matheus , García de Lima João Vitor , Da Silva Maia Sonicley , Sanchez José Sanchez-Choy , Panduro Tenazoa Nadia Masaya 
Published: May 2020

The objective in this study was to determine the nutrient contents in Myrciaria dubia plants in function of five K2O doses (0, 40, 80, 120 and 160 kg ha-1) applied through fertigation. Leaf dry matter (LDM), total dry matter (TDM), and leaf nutrient contents were evaluated. The LDM and TDM were higher in plants subjected to the dose of 160 kg ha-1 of K2O, with 52.44 g and 302.69 g, respectively. Leaf N and K contents were 22.15 and 9.48 g kg-1 in response to 160 kg ha-1 of K2O. The mean P, Ca and S contents were 1.6, 17.89 and 1.61 g kg-1, respectively, and the content of Mg2 + decreased from 5.62 to 2.74 g kg-1 at the dose of 0 and 160 kg ha-1 of K2O, respectively. The B, Mn and Fe contents decreased from 136.5 to 100.0, 346.24 to 248, and from 142.06 to 97.35 mg kg-1 at the dose of 0 and 160 kg ha-1 of K2O, respectively. The mean Cu and Zn contents were 3.81 and 40,54 mg kg-1, respectively, at the K2O doses. The nutrient content determined in the leaves of M. dubia were adequate for the development of the species in the first year of cultivation, presenting the following decreasing order: N> Ca> K> Mg> P = S> Mn> B> Fe > Zn> Cu.
Responses of sour passion fruit (<i>Passiflora edulis</i> Sims) seeds from the third recurrent selection cycle during storage
Authors: Rodrigues Daniele Lima , Viana Alexandre Pio , Vieira Henrique Duarte , Santos Eileen Azevedo , E Silva Fernando Higino Lima 
Published: May 2020

Conflicting responses have been found for the period of conservation of passion fruit seeds. Therefore, this study aimed to evaluate the response of the seeds of passion fruit progenies to a 24-month storage period. The sour passion fruit progenies from the third cycle of Universidade Estadual do Norte Fluminense Darcy Ribeiro - UENF intrapopulation recurrent selection program were grown in Itaocara- RJ and the progenies seeds were evaluated for: germination potential, germination first count, accelerated aging, first count of accelerated aging test, seedling and radicle size and germination speed index. The germination and vigor of the seeds of the full-sib progenies were assessed by analysis of variance and factorial arrangement with 3 progenies and 7 periods of storage and the averages were compared by Tukey test at 5% probability. Progenies 1 and 2 responded better to germination (92% for both progeny) and vigor test of accelerated aging (92% for both progeny), rootlet size (6.4 and 5.8 cm, respectively) and germination speed index (2.91 and 2.85, respectively) during storage. Variations were observed during the storage period in mean of progenies for germination (81-93%) and vigor for all traits, except accelerated aging (84-91%). At eight months of storage, the seeds presented increased vigor; at 16 months, they showed reduced vigor. The passion fruit seeds of the progenies under analysis can be stored for up to 24 months with high and uniform germination rate and no loss in vigor. The seeds from the passion fruit breeding program showed increases in the variables of germination and vigor during the selection process for fruit production variables, proving the efficiency of the breeding program.
Desarrollar la inteligencia creativa en diseño: repensar la semiótica
Authors: Rodríguez Gómez Sergio 
Published: May 2020

La semiótica es un campo de estudio que ofrece herramientas y reflexiones útiles para la práctica del diseño y un recurso valioso en términos pedagógicos. Sin embargo, es común que la semiótica sea vista por los estudiantes de diseño y sus docentes como algo teórico críptico, abundante en teorías, meta-reflexión, términos extraños y oscuros, que guardan poca relación con sus carreras y su vida cotidiana. Esa percepción surge de la manera como se enseña, no de los fundamentos del campo. En este artículo planteo un modelo pedagógico de la semiótica que permite que los estudiantes de diseño adquieran, practiquen y desarrollen la inteligencia creativa y, de este modo, sean más hábiles y ágiles produciendo objetos/signos exitosos, en términos comunicativos, para los usuarios ideales a los que se dirigen. La inteligencia creativa es una clase de inteligencia que requiere la reflexión hábil y razonada acerca de la producción de signos y de la evaluación de su apreciación. Aquí propongo cómo lo que a veces asumimos como la intuición de los sujetos creativos –la habilidad transparente para resolver problemas artísticos y funcionales– puede potenciarse y hacerse evidente con las herramientas que ofrece la semiótica.
Positional factors in syllabification
Authors: Passino Diana 
Published: May 2020

AbstractFrom the perspective of standard generative phonological theory, syllable structure is not recorded in the lexicon but it is obtained by means of a syllabification algorithm based on a series of principles. In a given language, the algorithm should parse obstruent+liquid clusters as tautosyllabic both in word-initial and word-internal positions. The tautosyllabic parse as a branching onset complies with all principles on which the syllable-building algorithm is based. In standard theory, if branching onsets of obstruent+liquid are allowed in a language and documented in word-initial position, tautosyllabic parse is predicted to hold also word-internally. Likewise, Kaye’s (1992) Uniformity Principle makes the same prediction, since it states that sequences of contiguous positions that are in a governing relation and contain the same phonological material have the same constituent structure. The present paper draws attention to empirical data showing obstruent+liquid clusters being parsed tautosyllabically in word-initial position and heterosyllabically in word-internal position in the same language. An account is proposed to explain the data discussed, claiming that positional factors may also be relevant in determining syllabification.
The English “Arab Rule” without feet
Authors: Dabouis Quentin , Enguehard Guillaume , Fournier Jean-Michel , Lampitelli Nicola 
Published: May 2020

AbstractThis paper deals with English vowel reduction and focuses on what is generally referred to as the Arab Rule (Ross 1972 i.a.). Vowels tend to reduce if the preceding syllable is light, whereas they do not reduce if the preceding syllable is heavy. Our purpose is twofold: first, based on the scrutiny of Wells (2008), we evaluate the efficiency of the Arab Rule and show that is empirically verified. Second, we propose an analysis of blocking contexts couched within CVCV phonology (Lowenstamm 1996). We use two central notions such as Government and Licensing, and show that vowel reduction only applies to “governing-and-governable” vowels.
Whole-Body Characterization of Estrogen Receptor Status in Metastatic Breast Cancer with 16α-18F-Fluoro-17β-Estradiol Positron Emission Tomography: Meta-Analysis and Recommendations for Integration into Clinical Applications
Authors: Kurland Brenda F. , Wiggins Jay R. , Coche Amandine , Fontan Charlotte , Bouvet Yann , Webner Peter , Divgi Chaitanya , Linden Hannah M. 
Published: May 2020

AbstractEstrogen receptor (ER) status by immunohistochemistry (IHC) of cancer tissue is currently used to direct endocrine therapy in breast cancer. Positron emission tomography (PET) with 16α-18F-fluoro-17β-estradiol (18F-FES) noninvasively characterizes ER ligand–binding function of breast cancer lesions. Concordance of imaging and tissue assays should be established for 18F-FES PET to be an alternative or complement to tissue biopsy for metastatic lesions. We conducted a meta-analysis of published results comparing 18F-FES PET and tissue assays of ER status in patients with breast cancer. PubMed and EMBASE were searched for English-language manuscripts with at least 10 patients and low overall risk of bias. Thresholds for imaging and tissue classification could differ between studies but had to be clearly stated. We used hierarchical summary receiver-operating characteristic curve models for the meta-analysis. The primary analysis included 113 nonbreast lesions from 4 studies; an expanded analysis included 327 total lesions from 11 studies. Treating IHC results as the reference standard, sensitivity was 0.78 (95% confidence region 0.65–0.88) and specificity 0.98 (0.65–1.00) for the primary analysis of nonbreast lesions. In the expanded analysis including non-IHC tissue assays and all lesion sites, sensitivity was 0.81 (0.73–0.87) and specificity 0.86 (0.68–0.94). These results suggest that 18F-FES PET is useful for characterization of ER status of metastatic breast cancer lesions. We also review current best practices for conducting 18F-FES PET scans. This imaging assay has potential to improve clinically relevant outcomes for patients with (historically) ER-positive metastatic breast cancer, including those with brain metastases and/or lobular histology.