bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparative analysis between intralesional 5-fluorouracil versus surgical excision with intralesional triamcinalone acetonide in keloid excision
Authors: Thomas Ritty Ann , Patel Vasim Ismail 
Published: April 2020

<p class="abstract"><strong>Background:</strong> Keloids are characterized by an uncontrolled proliferation of fibrous tissue after injury of the skin and has been treated by various modalities. Recently, newer therapeutic modalities have been studied including intralesional 5-FU, verapamil, laser therapy, cryotherapy, silicone sheet dressings, irradiation, retinoids, tacrolimus, imiquimod and combination therapy. The aim of this study is to analyse the response of intralesional 5-FU alone with that of intralesional triamcinolone acetonide with surgical excision thus to provide the best possible treatment modality to patients.</p><p class="abstract"><strong>Methods:</strong> Sixteen patients having keloid in head and neck region were taken into the study and divided into two groups after a routine blood check-up. Group A intralesional 5-FU once in three weeks for six sessions. Group B surgical excision followed by intralesional triamcinalone acetonide once weekly for six sessions. Patients were followed up for one year. </p><p class="abstract"><strong>Results:</strong> In group A, 7 patients came for review regularly. Aesthetic improvement was excellent for 6 but was considerably painful for all. In group B, 8 patients came for regular review, 6 had minimal scarring and all patients complained of mild pain post operatively.</p><p><strong>Conclusions:</strong> Intralesional 5-FU can be a very effective treatment modality for keloids, with no recurrence noted, except for its poor tolerability owing to side effects such as pain, nausea and vomiting. Classical method of surgical excision followed by intralesional steroids is better tolerated but has higher recurrence rates. </p>
Evaluation of single stage tympanomastoid surgery in unsafe chronic suppurative otitis media in Kashmiri population: a cross sectional study
Authors: Mir Parvez Ahmed , Makhdoomi Owais , Abbas Syed Waseem 
Published: April 2020

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is typically a persistent disease insidious in ONSET, affecting the mucoperiosteal lining of middle ear cleft, often capable of causing severe destruction and irreversible sequelae and manifests clinically with hearing impairment and discharge. Successful management of unsafe CSOM has posed challenge before otolaryngologists for ages.</p><p class="abstract"><strong>Methods:</strong> The prospective study is based on 40 patients of unsafe CSOM who were managed and followed up in the post graduate department of otorhinolaryngology and head and neck surgery of Government medical college Srinagar with relevant data was recorded on the proforma. </p><p class="abstract"><strong>Results:</strong> All the patients who underwent single stage tympanomastoid surgery with or without ossicular chain reconstruction had no evidence of recurrent disease at follow up with 82.5% were below the age of 40, of which 40% were between 21 to 30 years. Males were more involved than females (1.2:1), also CT scan findings were co related with intra operative findings during our study.</p><p class="abstract"><strong>Conclusions:</strong> In conclusion a perfectly performed canal wall down mastoidectomy with tympanoplasty with us without ossiculoplasty in same sitting give good and acceptable post-operative results as far as the hearing improvement and dry and safe ear is concerned.</p>
Comparative study of 0.5% bupivacaine infiltration versus sterile water infiltration in tonsillar fossa during tonsillectomy performed under general anaesthesia
Authors: U. P. Santosh , V. C. Sanjay 
Published: April 2020

<p class="abstract"><strong>Background:</strong> Tonsillectomy is a treatment of choice when medical line treatment is failed in chronic tonsillitis. Post tonsillectomy pain is the most common problem of this surgery which may persists for weeks and affect normal daily activities. Use of opiods and non-steroidal anti-inflammatory drugs for relieving pain may leads to nausea, vomiting and post tonsillectomy haemorrhages. We renewed interest in infiltration of local anaesthetic drug in the tonsillar fossa during tonsillectomy. To evaluate the efficacy of 0.5% bupivacaine infiltration in tonsillar fossa during tonsillectomy under general anaesthesia in terms of post-operative pain relief.</p><p class="abstract"><strong>Methods:</strong> It is double blinded prospective comparative study was carried out on 100 patients of either sex and age 5-40 years who diagnosed with chronic tonsillitis undergoing tonsillectomy and willing to participate in study were included.50 patients were infiltrated with sterile water and other 50 patients were infiltrated with 0.5% bupivacaine in the tonsillar fossa during tonsillectomy performed under general anaesthesia. Postoperatively at 2nd, 6th, 24th hours and 7th day all patients were evaluated for pain score by using visual analogue scale. </p><p class="abstract"><strong>Results:</strong> In our study, post-operative pain mean score 2nd, 6th, 24th hour and 7th day post-operative period for test and control group was “3.3 and 7.1”, “3.2 and 5.2”, “1.7 and 4.8” and “0.6 and 2.2” respectively which was found to be statistically significant (p&lt;0.001).</p><p class="abstract"><strong>Conclusions:</strong> 0.5% bupivacaine infiltration in the tonsillar fossa during tonsillectomy had lower pain score in post-operative period compare to sterile water infiltration.</p><p class="abstract"> </p>
Regional prevalence of different types of sinusitis at a tertiary care centre in Northern India
Authors: Khan Abdul Rehman , Siddiqui Farzana 
Published: April 2020

<p class="abstract"><strong>Background:</strong> The aim of the study was to determine the incidence of different types of rhinosinusitis in patients attending ENT Department OPD at a tertiary care centre in Ruhelkhand area of Northern India.</p><p class="abstract"><strong>Methods:</strong> This study was done at department of Otorhinolaryngology, RMRI, Bareilly, India, a tertiary-care Teaching hospital. A total number of 39823 patients (22379 females, 17444 males) were included in this study from December 2017 till February 2020. Age range of selected patients was 3 months to 76 years, 3883 patients were having Rhinosinusitis and remaining having other ENT diseases. </p><p class="abstract"><strong>Results:</strong> During 27 months period from December 2017 to February 2020, 39823 patients were seen in the OPD and patients were categorized in different disease groups, like chronic suppurative otitis media and acute suppurative otitis media, upper respiratory tract infections, acute and chronic tonsillitis and pharyngitis. Fourth most common disease group was different types of rhinosinusitis.</p><p class="abstract"><strong>Conclusions:</strong> In this study assessment was done of different ENT patients attending OPD. Chronic rhinosinusitis (46.1%) was the most common type of rhinosinusitis, followed by Acute type (29.7%).</p>
IMPLEMENTATION OF EDUCATION MODEL 4.0: DEVELOPING INDUSTRY 4.0 SKILLS IN GRADUATES ENGINEERS FOR IMPROVING EMPLOYABILITY SKILLS
Authors: Singh Dheeraj , Tilak Geetali 
Published: April 2020

Purpose of the study: With the growing technologies, unemployment is a big issue for youngsters, which is a big challenge in itself due to lack of skills among the youngsters The main purpose of this study is to shows, how the education 4.0, in-line with industry 4.0, to develop and optimize personalized education, would ultimately determine how young people of the future will work and live in. Methodology: Both quantitative and qualitative data are used in this research study. For this research as a survey questionnaire is used for collecting primary data. Data Collection and analysis methods are adopted wherein the questionnaire is circulated amongst various stakeholders like engineering students, faculty and industry experts in Pune City. Main Findings: A conceptual framework is proposed to identify factors affecting uncertainty in employability and implementation of education 4.0 model aligned with industry 4.0 to overcome these factors for developing existing education is studied here. Applications of this study: Higher and technical educational institutes where every year more students are graduated with a technical education but a large percentage of them are not able to get employment. IT and manufacturing companies found a lack of skills in them and not ready to hire them. An educational institute is failing to fill this gap and more uncertainty in employment has occurred. This research will be helpful to the educational institutes to implement an education 4.0 model to enhance new parameters for restructuring the existing education that would be benefited for students and institutes to meet the requirements of industries. Novelty/Originality of this study: This study has proposed a new conceptual framework of identifying the factors that cause of unemployment gap between academia and industries. This study has focused on the implementation of education 4.0 model in line with industry 4.0 where readers will learn how a new model of education will be helpful to educational institutes in developing their existing education methods as well as will be benefited to the graduated students in terms of developing skills to cope with new emerging technologies.
Prevalencia y factores asociados con el consumo diario de cigarrillo en mujeres adultas de Bucaramanga, Colombia
Authors: Campo Arias Adalberto , Díaz Martínez Luis Alfonso 
Published: April 2020

Objetivo: el consumo de cigarrillo es un problema de salud pública que crece gradualmente en mujeres y se asocia con una importante morbimortalidad. El objetivo de este estudio fue hallar la prevalencia y los factores asociados con el consumo diario de cigarrillo en mujeres adultas.Diseño: estudio poblacional transversal.Lugar: población general de la ciudad de Bucaramanga, Colombia.Participantes: mujeres adultas letradas entre 18 y 65 años de edad.Intervenciones: ninguna.Principales resultados a medir: consumo diario de café, consumo abusivo de alcohol, trastornos mentales comunes y consumo diario de cigarrillo durante el último mes.Resultados: se entrevistaron 1.726 mujeres con edad promedio de 38,3 años (DE=13,3) y escolaridad promedio de 8,8 años (DE=3,9); 56,2% estaban casadas; 37,1% eran empleadas; 68% residían en estrato medio; 44,4% consumía diariamente café; 1,4% presentaba consumo abusivo de alcohol; y 15,8% informó un trastorno mental común. La prevalencia de fumadoras actuales fue 6,3% (IC95% 5,2-7,4). Luego de controlar por escolaridad, el consumo diario de cigarrillo se asoció con el consumo abusivo de alcohol (OR=5,1; IC95% 2,0-12,8; p=0,001); la presencia de un trastorno mental común (OR=3,5; IC95% 2,2-5,3; p<0,001), el consumo diario de café (OR=3,0; IC95% 1,9-4,6; p<0,001) y vivir en estrato socioeconómico bajo (OR=1,5; IC95% 1,0-2,4; p=0,042).Conclusiones: una de cada dieciséis mujeres de la población general consume cigarrillo diariamente. Es necesaria la promoción activa del abandono de este consumo en esta población.
Perfil lipídico por trimestres de gestación en una población de mujeres colombianas
Authors: Landázuri Patricia , Restrepo Beatriz , Trejos Juanita , Gallego Martha Lucía , Loango Chamorro Nelsy , Ocampo Rodrigo 
Published: April 2020

Introducción: El embarazo se acompaña de cambios en el metabolismo materno de las lipoproteínas para satisfacer las demandas nutricionales del feto. El objetivo de este trabajo fue determinar el comportamiento del perfil lipídico durante los diferentes trimestres en una población de gestantes colombianas.Metodología: el colesterol total, las lipoproteínas y los triglicéridos fueron estudiados en 422 mujeres durante los tres trimestres del embarazo. Colesterol, triglicéridos y lipoproteínas fueron medidos en suero por métodos enzimáticos.Resultados: Los triglicéridos (128,2 ± 85,8; 238,6 ± 130,2; 305,1 ± 168,7 mg/dL), el colesterol total(180,3; 235,8; 270 ± 107,1 mg/dL), las lipoproteínas de muy baja densidad (25,6 ± 17,2; 47,5 ± 25,8; 59,9 ± 31,7 mg/dL) y las lipoproteínas de baja densidad (123,8 ± 69,2; 158,3 ± 77,6; 185 ± 102,6 mg/dL). Las diferencias en las variables fueron estadísticamente significativas trimestre a trimestre (todos las p <0,001).Conclusiones: estos resultados muestran cambios metabólicos en el perfil lipídico durante el embarazo, los datos pueden ser de interés médico para hacer seguimiento a aquellas gestantes con perfil lipídico alterado, diabetes gestacional, hipertensión u otras enfermedades relacionadas.
Elżbieta Zawacka (1909–2009) – zasłużony żołnierz i aktywna „feministka”
Authors: Marcinkiewicz-Kaczmarczyk Anna 
Published: April 2020

Elżbieta Zawacka, już w okresie przedwojennym, poświęciła się zarówno działalności wojskowej, jak i pedagogicznej, czynnie angażując się w działalność Przysposobienia Wojskowego Kobiet i pełniąc m.in. funkcję Komendantki PWK Rejonu Śląskiego. W ramach tej działalności m.in. organizowała i prowadziła szkolenia dla młodzieży. Po ataku wojsk niemieckich czynnie uczestniczyła w kampanii wrześniowej, a następnie wstąpiła do armii podziemnej, podejmując służbę najpierw w łączności, a potem kurierską. W ramach tej ostatniej przewiozła pocztę do Sztabu Naczelnego Wodza w Londynie, gdzie również prowadziła rozmowy na temat łączności oraz uregulowania prawnego służby wojskowej kobiet. Z Londynu powróciła na ziemie polskie, wykonując skok spadochronowy z cichociemnymi, a następnie uczestniczyła w powstaniu warszawskim. Po zakończeniu wojny poświęciła się pracy naukowej i pedagogicznej. Jedną z jej zasług w okresie powojennym było utworzenie Fundacji Generał Elżbiety Zawackiej, Archiwum i Muzeum Pomorskiego Armii Krajowej oraz Wojskowej Służby Polek.
Za swoje zasługi w działalności militarnej, a także na polu naukowym, pedagogicznym i społecznym E. Zawacka otrzymała nagrody i wyróżnienia. Jeszcze w okresie wojny została odznaczona m.in. Krzyżem Walecznych, Krzyżem Zasługi i Krzyżem Armii Krajowej, a po wojnie, w 2006 r. otrzymała stopień generała brygady. Oprócz tego w 1995 r. odznaczono ją Orderem Orła Białego, a w 2002 r. Prezes IPN nadał jej tytuł Kustosza Pamięci Narodowej.
Przez całe swoje życie E. Zawacka łączyła pracę militarną, społeczną i pedagogiczną. Jej postawa świadczyła o tym, że umiała walczyć o swoje prawa, nie rezygnowała z obranego celu i niezależnie od okoliczności kontynuowała karierę zawodową. W tym kontekście można ją nazwać zarówno zasłużonym żołnierzem, jak i „feministką”.
Kontrast Ajanlar; Farmakolojik Özellikleri, Genel Advers Reaksiyonları ve İlaç Etkileşimleri
Authors: ÇELİK AYDIN Özlem , AYDIN Sonay , GÜNEY Hakkı 
Published: April 2020

Kontrast ajanlar, genel radyoloji pratiğinde sıklıkla kullanılmaktadırlar. Kontrast ajanları temel olarak iyotlu kontrast ajanları ve gadolinyum bazlı kontrast ajanları olarak ayrılırlar. Bu derlemede amaç, genel kontrast ajanlarının temel farmakolojik özelliklerini, uygulama sonrasında görülen advers reaksiyonları ve ilaç etkileşimlerini özetlemektir.
Contrast agents are commonly used in general radiological practice. Contrast agents are classified into two main groups: iodinated contrast agents and gadolinium based ones. In this review, we aim to summarize the pharmacological properties of contrast agents, their adverse reactions and drug interactions.
Keywords: Radiocontrast, Iodine, Gadolinium, Adverse reaction
Open Obturator Hip Dislocation
Authors: Medda Suman , Araiza Edgar T. , Pilson Holly T. 
Published: April 2020

Case:
An open obturator dislocation with associated pelvic ring injury and perineal wound underwent fixation and aggressive debridement. Despite this, the patient proceeded to infection requiring additional debridements and prolonged intravenous antibiotics. At 18 months postinjury, the patient developed avascular necrosis and significant heterotopic ossification; however, she was able to ambulate.

Conclusions:
Open obturator dislocations of the hip require a multidisciplinary team. Despite prompt antibiotic therapy and aggressive debridement, patients are at high risk of infection because of the microbial environment in this region. Open obturator hip dislocations are at significant risk of avascular necrosis despite timely reduction.
High-throughput transcriptomic analysis reveals new players in popcorn (Zea mays) aluminum resistance
Authors: Pinto Vitor Batista , Ferreira Priscila Gonçalves , Vidigal Pedro Marcus Pereira , Mendes Tiago Antônio de Oliveira , Dal-Bianco Maximiller , Viana José Marcelo Soriano 
Published: April 2020

Abstract
The authors have withdrawn this preprint due to a need to make corrections.
Spirituality and Quality of Life in Older Adults: Path Analyse Model
Authors: Lima Sara , Teixeira Lurdes , Esteves Raquel , Ribeiro Fátima , Teixeira Ana , Pereira Fernanda , Magalhães Clarisse 
Published: April 2020

Abstract
Background: Study older adults’ quality of life is becoming increasingly important in the assessment, quality improvement and allocation of health and social care service. The purpose of this study was to enhance knowledge on the relationship between modifiable (psychological variables) and non-modifiable variables (sociodemographic), and quality of life in elderly, regarding psychological and social variables in Portuguese context.Methods: This is a cross-sectional study, including 604 older adults from general community. 63.6% of the sample was composed by female gender with a mean age of 71.6(SD=4.81). Participants completed the following instruments: Barthel Index to assess functionality; Satisfaction with Social Support Scale to assess social support; The Spiritual and Religious Attitudes in Dealing with Illness to assess spirituality and Short Form Health Survey 36, to assess mental and physical quality of life.Results: A path analysis model was performed where the presence of a chronic disease, age and functionality has a direct effect on physical quality of life and spirituality had a direct effect on mental quality of life. Social support mediated the relationship between functionality and mental quality of life, and in turn, functionality mediated the relationship between age and physical quality of life.Conclusions: Results reinforce the effect of age and chronic disease as non-modifiable variables as well as functionality, spirituality and satisfaction with social support as modifiable variables, in the quality of life of older people. Social support, health and education programs in the community should be promoted in order to improve quality of life in this population. Strategies to promote functionality and enhance the social support network, especially in the elder with chronic illness, should be a priority.
Patient-reported outcomes following primary total hip arthroplasty in Crowe type Ⅲ or Ⅳ developmental dysplasia are comparable to those in Crowe type Ⅰ: a case-control study of 96 hips with intermediate-term follow-up
Authors: Ueoka Ken , Kabata Tamon , Kajino Yoshitomo , Inoue Daisuke , Ohmori Takaaki , Ueno Takuro , Yoshitani Junya , Yamamuro Yuki , Tsuchiya Hiroyuki 
Published: April 2020

Abstract
Background: A few previous studies have investigated patient satisfaction following total hip arthroplasty (THA) according to the degree of pelvic deformity. This study compared patient-reported outcomes following primary THA for Crowe types Ⅲ, Ⅳ and I dysplasia.Methods: This was the retrospective case-control study assessed patients who underwent primary THA by a single surgeon at a single institution from 2008 to 2016. We sent postal questionnaires to 38 patients with Crowe type III and IV dysplasia. Among the questionnaire respondents, 23 patients, excluding cases with a follow-up period of less than 1 year, were enrolled as the H group. The control group included 46 patients with Crowe type I, matched for sex, age, body mass index and surgical approach. To investigate the influence of femoral shortening osteotomy, the H group was divided according to whether or not femoral shortening osteotomy was performed. Ten patients underwent THA with femoral shortening osteotomy (FO group), while 12 patients underwent THA without femoral shortening osteotomy (N-FO group). Patient demographics, average follow-up period, surgical information, pre- and postoperative leg length discrepancy (LLD), and perioperative complications were investigated. Clinical evaluations were performed using the Japanese Orthopaedic Association (JOA) scores, 36-item short-form survey (SF-36), net promotor score (NPS), visual analogue scale (VAS), and questionnaires. The VAS and SF-36 was acquired at only final follow-up. Results: The H and control groups were not significantly different in the postoperative JOA scores and SF-36. In the H group, VAS at the final follow-up was significantly higher, and significantly more patients felt that postoperative rehabilitation was serious, expressing that they underwent THA for LLD correction. Additionally, VAS in the FO group was higher than those in the N-FO group. Postoperative LLD was significantly greater in the H group than in the control group. Each group had the NPS of over 50.Conclusion: The postoperative VAS was higher in Crowe type Ⅲ and Ⅳ dysplasia than in Crowe type I dysplasia, but there were no significant differences in the postoperative satisfaction, JOA score and SF-36. The findings may help explain the effects of THA preoperatively to patients with Crowe type Ⅲ and Ⅳ dysplasia.Level of Evidence: Therapeutic Level 3b
The association between psychological characteristics and physical activity levels in people with knee osteoarthritis: a cross-sectional analysis
Authors: Uritani Daisuke , Kasza Jessica , Campbell Penny K. , Metcalf Ben , Egerton Thorlene 
Published: April 2020

Abstract
Background:The aim of this study was to examine the relationship between psychological characteristics and physical activity levels, measured as the average number of steps per day, in people with knee osteoarthritis (OA).Methods: This study analysed baseline data from a randomized controlled trial (Australian New Zealand Clinical Trials Registry reference: ACTRN12612000308897). A total of 167 adults aged over 50 years, with knee pain rated as four or more on an 11-point numeric rating scale, and knee OA diagnosed using American College of Rheumatology clinical criteria, were recruited from the community (62 men and 105 women; mean age, 62.2 ± 7.5 years). The average number of steps per day over seven consecutive days was measured using an accelerometer-based device. Psychological characteristics evaluated were: depressive symptoms (Depression Anxiety Stress Scale), self-efficacy (Arthritis Self-Efficacy Scale for pain and other symptoms), fear of movement (Brief Fear of Movement Scale for Osteoarthritis), and pain catastrophizing (Pain Catastrophizing Scale). The association between the average number of steps per day and psychological characteristics was analyzed using a multiple linear regression analysis, with the average number of steps per day as the dependent variable, adjusting for each psychological characteristic separately, and age, sex, body mass index, and pain entered as covariates.Results: There was evidence that the amount of physical activity was associated with fear of movement (coefficient [B]: -117, 95% confidence interval [95%CI]: -227 to -8) and with pain catastrophizing (B: -44, 95%CI: -86 to -1). The association with self-efficacy was similar (B:117, 95%CI: -12 to 246). However, the direction of the association with depressive symptoms was less clear (B: -59, 95%CI: -138 to 19).Conclusions: The results of this study revealed that the relationship was such that lower fear of movement and lower pain catastrophizing may be associated with more steps per day. It may be hypothesized that fear of moving and pain catastrophizing lead to activity avoidance and that strategies to improve these disease-related psychological aspects may be useful in enhancing physical activity participation, although this hypothesis is highly speculative and needs further testing given the cross-sectional design of this study.