bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting Medication Adherence Based on Personality Characteristics in Individuals with Type 2 Diabetes Mellitus
Authors: Aflakseir Abdulaziz , Nikroo Farzad , Mollazade Javad 
Published: October 2020

Objective: Diabetes mellitus is a chronic illness and adherence to medications is vital to manage the illness. The purpose of this study was to examine the prediction of medication adherence based on personality factors in a group of individuals with type 2 diabetes in Yasuj.
Materials and Methods: One hundred twenty individuals with type 2 diabetes who visited health centers were selected for this study through convenience sampling. The participants completed the NEO-Five Factor Inventory and Medication Adherence Rating Scale (MARS). The data were analyzed by mean, standard deviation, and multiple regression analysis using SPSS software.
Results: The results showed that among the big-five personality factors, only neuroticisms significantly predicted adherence to medications (β= -0.31, P-value< 0.003). Furthermore, the model explained only 19% of the variance in medication adherence (R2= 0.19, P-value< 0.01).
Conclusion: This study indicated that a large proportion of patients with type 2 diabetes did not adhere to their medications. This study highlighted that the personality trait of neuroticism was important in predicting medication adherence in patients with type 2 diabetes.
ESTRATÉGIAS DE REPRODUÇÃO DAS ELITES POLÍTICAS E INTELECTUAIS NO BRASIL EM FINS DO XIX
Authors: Bordignon Rodrigo da Rosa 
Published: October 2020

O presente artigo se dedica ao exame das estratégias de reprodução das elites políticas e intelectuais no Brasil em fins do século XIX. Neste texto, são analisadas as relações entre origens geográfcas e sociais, a escolarização e a primeira ocupação que compõem as carreiras dos agentes em pauta. O objetivo principal é apreender as estratégias de reprodução, e sua diferenciação relativamente aos recursos sociais e escolares que as respaldam, confrontando-as aos instrumentos disponíveis e às transformações na simbologia de excelência social. Os principais resultados apontam para a centralidade da desigualdade de chances no que tange às condições de escolarização e, igualmente, aos pontos de entrada das carreiras.Palavras-chave: Origens sociais. Destinos. Estratégias de reprodução.Elites.POLITICAL AND INTELLECTUAL ELITES REPRODUCTION STRATEGIESIN BRAZIL BY THE END OF 19TH CENTURYAbstractThis research dedicates itself to the examination of reproduction strategies from the political and intellectual elites in Brazil by the end of the 19th century. In this paper, we analyze the relations between geographical and social origins, schooling, and the first occupation that compose the agents’ careers. The main goal is to apprehend the reproduction strategies and its differentiation with regards to the social and schooling resources that support the agents confronting them to the instruments that are available and the transformations in the social excellence symbology. The main results indicate the centrality of inequalities in terms of chances with regards to the conditions of schooling and, equally, to the career entrance points.Keywords: Social origins. Destination. Reproduction strategies. Elites.
O LE MÉTIER DE SOCIOLOGUE É UM CLÁSSICO NA SOCIOLOGIA FRANCESA DA ATUALIDADE?
Authors: Duval Julien 
Published: October 2020

Conferência proferida no Colóquio Internacional: O ofício de sociólogo e o trabalho sociológico de Pierre Bourdieu. Universidade Federal de Santa Catarina, Florianópois – SC, 17 de maio de 2018. Tradução de Rodrigo da Rosa Bordignon. Revisão de Igor Gastal Grill.
UMA GRANDE FAMÍLIA
Authors: Martin Monique de Saint 
Published: October 2020

Portador de um dos mais prestigiosos títulos e nomes, herdeiro de uma grande família da nobreza militar que “serviu a França por 500 anos”, ex-aluno da Ecole Polytechnique, diretor-presidente de uma das filiais da Schneider, o décimo segundo duque de Brissac, que se casou com May Schneider, uma descendente de uma das maiores famílias de industriais, é a realização do aristocrata perfeito, possuindo um notável conjunto de qualidades e características distintivas. O capital social herdado de sua família e que ele jamais deixou de manter e valorizar, ao mesmo tempo em que sabia, ocasionalmente, reconvertê-lo, está, sem dúvida, na raiz desta concentração de riquezas. Centro de uma rede de relações com uma extensão e densidade excepcionais, o duque de Brissac adquiriu desde a infância, nos estabelecimentos de ensino secundáriode “boa companhia” que frequentou, a arte e o gosto de cultivar as relações herdadas, e de as ampliar. A análise das memórias do duque de Brissac e de várias obras escritas por outros membros de sua família permitiu reconstruir a história desse empreendimento de acumulação e gestão de capital social.Palavras-chave: Capital social. Redes de relações. História. Brissac.A GREAT FAMILYThe bearer of one of the most prestigious titles and names, the heir to a great family of the military nobility in which “they have servedFrance for 500 years”, a former pupil of the Ecole Polytechnique, managing-director of one of the sister-companies of the SchneiderCorporation, the Twelfth Duke of Brissac, who married May Schneider, a descendant of one of the greatest ironmasters families, is therealisation of the perfect aristocrat, possessing a remarkable aggregate of qualities and distinctive features. The social assets handed down to him by his family which he has constantly built up, maintained and exploited while knowing, whenever the occasion demanded, how to reconvert it, are, without doubt at the root of this concentration of riches. At the focal point of an exceptionally widespread and dense network of relations, the Duke of Brissac has acquired, from infancy and later in “well-bred” High Schools, a taste for cultivating and extending the kinship networks devolved on him through inheritance. The analysis of the memoirs of the Duke of Brissac and of several works written by other members of his family has enabled the author to trace the history of this pursuit of the accumulation and management of social assets.Keywords: Social capital. Networks. Family. History. Brissac.
FAMÍLIAS DAS ARMAS: REPRODUÇÃO FAMILIAR E CARREIRAS NO EXÉRCITO BRASILEIRO (1850-1930)
Authors: Seidl Ernesto 
Published: October 2020

Este artigo discute as condições de constituição de uma fração das elites militares a partir do estudo de grupos familiares cuja existência, reprodução e notabilização, ao longo de gerações, dependeram do Exército e de outras estruturas do Estado. A análise centra foco no grupo dos Menna Barreto e demonstra como o acesso privilegiado à carreira e valorização institucional de atributos angariados pelo grupo revelam o alto ajuste entre a oferta de oportunidades, no interior do serviço estatal a certas frações sociais, e as estratégias de reprodução que lograram acionar, perpetuando assim a própria instituição. É dada atenção especial aos condicionantes históricos de estruturação do Estado no período, e ao peso das estratégias matrimoniais e de notabilização efcazes na construção de patrimônios sociais erigidos em torno da ideia de “serviço ao Exército brasileiro”.Palavras-chave: Elites do Exército. Grupos familiares. Reprodução social. Menna Barreto.ARMY FAMILIES: FAMILY REPRODUCTION AND CAREERS IN THE BRAZILIAN ARMY (1850-1930)AbstractThis article discusses the forming of part of the military elites in Brazil. The research was based on the study of family groups whose existence, reproduction and notabilization throughout generations reliedon the Army and on other structures of the State. Focusing on the Menna Barreto family, the analysis shows that a privileged access to the career and other key attributes amassed by the group reveal a highadjustement between opportunities within the State services, at the reach of only certain social fractions, and the strategies of reproduction that they put into action, thus perpetuating the institution itself. Specialattention is given to the historical factors of State-buildion process in the period, as well as to the weight of effective marital and notabilization strategies in the making of social heritages erected around the ideaof “servin the Brazilian Army”.Keywords: Army elites. Family groups. Social reproduction. Menna Barreto.
MULHERES REPRESENTANTES NO CONGRESSO NACIONAL: TRABALHO POLÍTICO, APRESENTAÇÃO DE SI E RITUAIS DE RECONHECIMENTO
Authors: Barreira Irlys Alencar F. 
Published: October 2020

O artigo retoma informações de pesquisa realizada no Congresso Nacional, baseando-se também em outros estudos empíricos que atentam para problemáticas concernentes ao trabalho político de parlamentares, ao longo da última década. O trabalho parlamentar é focado em seu realce mais simbólico, atentando para os seguintes aspectos: modos discursivos de apresentação de si, entendidos pela maneira como as mulheres interpretam sua entrada no Parlamento, o espaço de organização do coletivo “bancada feminina” e as formas ritualizadas de expor a atuação política de mulheres na história do Congresso. São situações que registram diferentes práticas e percepções relacionadas à busca de reconhecimento e expressão do trabalho parlamentar. O artigo explora as estratégias de organização e de reconhecimento que acompanham o trabalho de mulheres em cargos de representação política que implicam em investimentos e formas estratégicas de organizar demandas.
Implementasi Variabel Makro: Zakat, Infak Dan Shodaqah (Zis) Pada Pelaku Ekonomi Kreatif Makanan Siap Saji Berbasis Singkong
Authors: Masyhuri. Masyhuri 
Published: October 2020

The purpose of this study is the impact of macro variables on zakat, shodaqah and infaq (Zis) on economic growth (aggregate demand; AD). The initial impact is controlled from the macro variables of consumption, investment, saving and government expenditure. This study is included in the basic research category because the level of technological readiness is 3 (three), namely at the laboratory level. Analysis tools are carried out using a graphical and mathematical approach. The results showed that Zis has a sectoral impact on economic growth (AD). The consumption, investment, saving, government expenditure and export variables have a positive impact on AD. Likewise Zis role in economic growth is positive. Whereas interest money has a negative impact. Anticipation without using interest money in the economy is done by increasing economic activity through the implementation of 14 sharia transactions. One of them is the application of qardhul-hasan to the creative economy of cassava-based fast food creative, which shows that the acceleration of the value of the currency compared to the future value can be created at 6.7 % -10% from before. That is why Zis besides having a positive impact on economic growth (AD) also gave birth to blessing as measured through 3 indicators of blessing, namely ni'mah, sa'adah (goodness) and ziyadah (additional).
STUDY OF ANTIATHEROSCLEROTIC AND ENDOTHELIOPROTECTIVE ACTIVITY OF PEPTIDE AGONISTS OF EPOR/CD131 HETERORECEPTOR
Authors: Puchenkova Olesya A. , Nadezhdin Sergey V. , Soldatov Vladislav O. , Zhuchenko Maxim A. , Korshunova Diana S. , Kubekina Marina V. , Korshunov Evgeny N. , Korokina Liliya V. , Golubinskaya Polina A. , Kulikov Aleksandr L. , Gureev Vladimir V. , Pokrovskiy Vladimir M. , Patrakhanov Evgeniy A. , Lebedev Petr R. , Denisyuk Tatyana A. , Belyaeva Veronika S. , Movchan Evgeniya A. , Lepetukha Elizaveta I. , Pokrovskiy Mikhail V. 
Published: October 2020

Introduction. The drugs affecting a mitochondrial dysfunction, oxidative stresses, apoptosis and inflammation of the vascular wall, have a high potential for the prevention and treatment of atherosclerotic lesions. In this regard, the use of EPOR/CD131 heteroreceptor agonists which have a similar spectrum of pharmacological effects, is one of the promising strategies in the treatment of cardiovascular diseases.Materials and Methods. The study was carried out on 68 C57Bl/6J male mice. Atherosclerosis was simulated in transgenic animals with an endotheliospecific knockdown of the Polg gene by simulating a balloon injury and keeping on a Western diet. Then, the studied drugs were injected once every 3 days at the dose of 20 μg/kg for 27 days. On the 28-th day, the animals were euthanized and the area of atherosclerotic plaques was assessed. The gene expression associated with the processes of inflammation, antioxidant protection, apoptosis, and angiogenesis was also determined in the aortic tissues. In addition, the endothelium protective effect of peptides on primary cultures of endothelial cells of wild and transgenic Polg-D257A mice was studied.Results. No statistically significant effect of drugs on the area of lipid infiltration have been found. However, the studied peptides have significantly reduced the expression of proinflammatory genes (iNos, Icam1, Vcam1, Sele, Il6, Tnfa), the genes associated with angiogenesis (Vegfa, Kdr, and Hif1a), the expression of proapoptic factors; they decreased the Bax/Bcl-2 ratio by more than 1.5 times. In addition, when supplemented with H2 O2 in vitro, peptides dose-dependently increased endothelial cell survival.Conclusion. The erythropoietin-based peptides can be used to improve the functional state of the vascular wall against the background of atherosclerotic lesions and have a depressing effect on pathobiological processes associated with a mitochondrial dysfunction. In addition, the studied peptides have a significant endothelial protective effect in the induction of oxidative stress in vitro.
USING QUANTUM-CHEMICAL PARAMETERS FOR PREDICTING ANTI-RADICAL (НО∙) ACTIVITY OF RELATED STRUCTURES CONTAINING A CINNAMOYL FRAGMENT II. DERIVATIVES OF 2’,4’-DIHYDROXYCHALCONE, FLAVANONE AND FLAVONE, CONTAINING A HYDROXY GROUP IN POSITION 7
Authors: Oganesyan Eduard T. , Shatokhin Stanislav S. 
Published: October 2020

42 derivatives of 2’,4’-dihydroxychalcone, flavanone and flavone, containing the hydroxy group in position 7 (ring "A"), as well as substituents in the ring "B", have been studied.The aim is to study the quantum-chemical parameters of 2',4'-dihydroxychalcone, flavanone and flavone derivatives containing a hydroxy group in position 7, in order to identify the effect of substituents on Mulliken charges (a.e) in the aromatic core "A", bond numbers (Nµ), the unsaturation index (IUA) and the electron density of the carbon atoms of the cinnamoyl fragment.Materials and methods. The listed above parameters have been calculated by the semi-empirical method PM7 (WinMopac 2016 program) on the workstation with an Intel Xeon E5-1620 3.5 GHz processor, 20 GB of RAM.Results. The analysis of the values of quantum-chemical parameters, as well as their comparison with the corresponding indicators presented in Report I, revealed a number of important features associated with the influence of the hydroxy group in position 7 (ring "A") on the studied quantum-chemical parameters of molecules. It has been established that the hydroxy group in the ring “A” does not significantly affect the Mulliken charge and the electron density of the carbon atoms of the propenone unit C-7→C-8→C-9. On atom C-9 (carbonyl carbon), the Mulliken charge always has a positive value, and the electron density is about 3.4670-3.4840 for all three groups of compounds. The transition from 2’,4’-dihydroxychalcone to flavanone and flavone by the formation of the pyrone heterocycle, is accompanied by an increase in the negative charge on C-8, which can be explained by the involvement of the oxygen heteroatom in the transmission of electronic effects. The hydroxy group in the ring “A”, has practically no effect on the charge and electron density of atoms. An analysis of the values of bond numbers and unsaturation indices suggests that atoms C-1 of 2’,4’-dihydroxychalcone and 7-hydroxyflavanone derivatives, are characterized by the lowest Nµ value; the lowest bond numbers are characteristic for atom C-8 derivatives of 7-hydroxyflavone. Consequently, the primary attack of the HO·radical will be directed at C-1 (in chalcones and flavanones) and at C-8 in flavones.Conclusion. The performed quantum-chemical calculations make it possible to analyze the effect on the main quantum-chemical parameters of the molecule, which can be useful in predicting the biological activity of flavanoid compounds due to their antiradical effect on reactive oxygen intermediate species (ROIs).
CHEMICAL CONSTITUENTS OF GEUM RIVALE L. AND THEIR BIOLOGICAL ACTIVITY
Authors: Orlova Anastasia A. , Povydysh Maria N. 
Published: October 2020

The aim of the study is to review the literature data on the chemical constituents of arial and underground parts of Geum rivale L. (Rosaceae) and the pharmacological activity of its extracts and individual compounds.Materials and methods. The study was carried out using Internet resources (Google Scholar, PubMed) and library databases (e-Library, Scopus, Web of Science). The main research methods were a review and analysis of the literature data on the topic for the period from 1958 up to the present.Results. For the period from 1958 up to the present more than 80 components in the arial and underground parts of G. rivale have been identified. Among them there were components of the essential oil, phenolic acids and coumarins, aglycones of flavonoids, including luteolin, apigenin, quercetin and kaempferol, as well as a number of their glycosides and glucuronides, ellagitannins (hemin A, B, C, D, pedunculagin, stachiurin/casuarinin, tellimagrandin I). Some aspects of the pharmacological activity of total extracts and individual secondary metabolites of G. rivale have been studied, anti-inflammatory, antioxidant, antimicrobial, antiviral activities have been experimentally confirmed.Conclusion. The analysis of the literature data showed that a further study of the composition of metabolites of G. rivale and their pharmacological activity is an urgent task, the solution of which will expand the range of use of this plant in medical practice and consider G. rivale as a promising source of pharmaceutical substances for the creation of new drugs and biologically active additives.
ANTITROMBOTIC ACTIVITY OF A NEW BENZIMIDAZOLE DERIVATIVE WITH A SPATIALLY DIFFICULT PHENOLIC SUBSTITUTE IN ITS STRUCTURE
Authors: Spasov Alexander A. , Kucheryavenko Aida F. , Gaidukova Ksenia A. , Chernikov Maxim V. , Zhukovskaya Olga N. 
Published: October 2020

The aimof the study was to investigate antithrombogenic properties of compound RU-1144 with previously identified pronounced antiplatelet and antioxidant activities. The thrombosis induced byFerric chloride(FeCl3) was carried out in rats’ carotid artery, in comparison with the known antiaggregant drugs - acetylsalicylic acid (ASA) and clopidogrel, as well as with the antioxidant preparation - ethylmethylhydroxypyridine succinate (EMHPS).Materials and methods.The antithrombotic activity of compound RU-1144 was studied on the model of the rats with carotid artery thrombosis, induced by the application of 50%ferric chloride(FeCl3), and the Global Thrombosis Test model (theGörög Thrombosis Test). The evaluation of this type of activity was carried out by prolonging the time of a blood clot formation. The studies of the compound RU-1144 effect on the bleeding time parameter were performed in mice. Acetylsalicylic acid, clopidogrel and EMHPS were used as reference drugs.Results.The antithrombotic effect of the RU-1144 substance revealed in the model of arterial thrombosis induced by the application offerric chloride(FeCl3), exceeded that of both acetylsalicylic acid and clopidogrel by 3.5 times and that of EMHPS by 2.9 times. In the modelof thein vitroGlobal Thrombosis Test (theGörög Thrombosis Test), compound RU-1144 reduced the thrombogenic potential of the blood equally with acetylsalicylic acid and clopidogrel. The assessment of “the bleeding time”, caused by the RU-1144 substance, showed that the prolongation of bleeding was twice as less pronounced than that caused by ASA and clopidogrel.Conclusion.The performed studies demonstrated a pronounced antithrombotic activity of compound RU-1144, which exceeded that of acetylsalicylic acid, clopidogrel and EMHPS, while the ability to prolong the bleeding time was reliably lower than that of reference drugs.Abbreviations:EMHPS-ethylmethylhydroxypyridine succinate; ASA - acetylsalicylic acid.
The Efek Enzim Bromelin Buah Nanas (Ananas comosus (L.) Merr) Berbasis Sediaan Gel terhadap Lebar Intertubulus Dentin
Authors: Alfiyanti Retno Dewi , Prihatiningrum Berlian , Budirahardjo Roedy 
Published: October 2020

Caries tissue cleaning can use Chemo-Mechanical Caries Removal (CMCR) based on proteolytic enzymes that catalyze peptide bonds into simpler compounds. Proteolytic enzymes can be found in mature pineapple bromelain enzymes. The aim of the study is to determine the effect of gel-based bromelain enzyme with concentrations of 8%, 10% and 12% against the width of the intertubulus dentin. The bromelain enzyme is extracted using the Lowry method. Then purified using 80% ethanol and diluting become to concentrations of 8%, 10% and 12%. Diluted bromelain enzymes were formed in gel preparations based on HPMC and applied to the study sample. The results of this study indicated a widening of the intertubulus dentin. This is indicated by the variation of the dentin intertubulus width > 2µm. This widening occurs because the bromelain enzyme can hydrolyze collagen in intertubulus dentin in the absence of alpha-l-antitrypsin. Hydrolysis causes the breaking of hydrogen bonds in the triple helix- shaped tropocollagen to turn into strands of polypeptide chains. The bromelain enzyme with a concentration 10% is more effective than 8% and 12% because it is within the maximum speed limit of the enzyme so that the enzyme is saturated by its substrate and there is a difference in specific enzyme activity in each concentration.
أنماط السيطرة الدماغية وعلاقتها في فاعلية الذات الإبداعية "دراسة تحليلية على عينة من الطلبة الموهوبين بمنطقة أبها"
Authors: حموري خالد عبدالله 
Published: October 2020

الملخص: هدفت هذه الدراسة إلى التعرف على أثر أنماط السيطرة الدماغية في فاعلية الذات الإبداعية، تكونت عينة الدراسة من (249( طالباً من الطلبة الموهوبين بمنطقة أبها، من المرحلتين المتوسطة والثانوية، وقد تم استخدام المنهج الوصفي التحليلي الارتباطي، وقد أشارت نتائج هذه الدراسة إلى أن النمط الكلي جاء بأعلى تكرار بلغ (117) وبنسبة مئوية بلغت (47,0%)، وكذلك أن طلاب المرحلة المتوسطة يسيطر عليهم النمط الكلي، وذلك بنسبة (32,5%)، أما المرحلة الثانوية فالنمط المسيطر عليهم هو الأيمن بنسبة (30,5%)، وحصول مجال الفاعلية الذاتية في التفكير الإبداعي على المرتبة الأولى، ووجود فروق ذات دلالة إحصائية (α ≥ 0.05) تعزى لأثر المرحلة في جميع المجالات لمقياس فاعلية الذات الإبداعية، وجاءت الفروق لصالح المرحلة الثانوية، وأخيرا وجود علاقة إيجابية موجبة دالة إحصائياً بين جميع أنماط السيطرة الدماغية وبين وفاعلية الذات الإبداعية.