bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Note on The Genus Evolvulus (Convolvulaceae) In Java, Indonesia
Authors: Irsyam Arifin Surya Dwipa , Hariri Muhammad Rifqi , Irwanto Rina Ratnasih , Mustaqim Wendy Achmad 
Published: June 2020

According to the Flora of Java, there is only one species of Evolvulus in Java, namely Evolvulus alsinoides. Since then, a second species was reported in 2017 from Universitas Indonesia, Depok, West Java, as an alien naturalized species. Some recent field studies have been conducted to provide updated taxonomic information of the genus on this island. The field observations were carried out in Banten, Jakarta, West Java, Jogjakarta, and East Java from March to December 2019. The herbarium studies were also conducted in Herbarium Bogoriense, Herbarium of Bogor Botanic Gardens, Herbarium Bandungense, and Herbarium of the Department of Biology, Universitas Indonesia. Our study reveals one newly recorded species of Evolvulus in Java already grown in cultivation, namely E. glomeratus Nees & Mart. subsp. grandiflorus (Parodi) Ooststr. Besides that, Evolvulus nummularius is now also reported to occur in other sites of West Java and extended to Central Java. An updated key to Evolvulus in Java, descriptions to both species, photographs, and brief discussions are provided.
Phase I Study of Alternate-Day Administration of S-1, Oral Leucovorin, and Bevacizumab for Refractory Metastatic Colorectal Cancer
Authors: Masuishi Toshiki , Taniguchi Hiroya , Komori Azusa , Mitani Seiichiro , Narita Yukiya , Kadowaki Shigenori , Ura Takashi , Ando Masashi , Muro Kei 
Published: June 2020

Abstract

Trial Information
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Lessons Learned
The recommended S-1 dose was 40 mg/m2, twice daily on Monday, Wednesday, Friday, and Sunday, with oral leucovorin and bevacizumab. Compared with daily administration, the alternate-day administration of S-1 with oral leucovorin may reduce mucositis with promising antitumor activity in refractory metastatic colorectal cancer.

Background
Daily S-1 plus oral leucovorin administration in a 1-week-on/1-week-off schedule has promising efficacy in gastrointestinal cancer but is associated with high risk of mucositis and diarrhea.

Methods
This phase Ib, 3+3 dose-escalation trial included patients with chemorefractory metastatic colorectal cancer (mCRC) receiving S-1 (40 mg/m2) and leucovorin (25 mg) orally twice daily (level 1, even-numbered days; level 2, Monday, Wednesday, Friday, and Sunday) and intravenous bevacizumab (5 mg/kg) every 2 weeks. Enrollment continued at the recommended dose level in the expansion cohort.

Results
We enrolled 21 patients (3 and 18 patients in levels 1 and 2, respectively). Briefly, 12 and 9 patients had Eastern Cooperative Oncology Group (ECOG) performance status of 0 and 1, respectively, and 8 and 13 patients had 1–3 and ≥4 prior treatment lines, respectively. Dose-limiting toxicity (DLT) was not observed, and level 2 was confirmed as the recommended dose. Common grade 3–4 adverse events at level 2 were anemia (22%), anorexia (6%), and diarrhea (6%). In the entire cohort, response rate, disease control rate, and median progression-free survival were 10%, 71%, and 4.2 months, respectively.

Conclusion
The recommended S-1 dose was 40 mg/m2, twice daily on Monday, Wednesday, Friday, and Sunday, with 25 mg oral leucovorin twice daily and 5 mg/kg bevacizumab every 2 weeks. Compared with the daily administration, alternate-day administration of S-1 plus leucovorin may reduce mucositis with promising antitumor activity in refractory mCRC.
Media Development Study Basic Techniques Of Handball Ball Based Adobe Flash Player On Coaching Extracurricular Son Handball Junior High School Level In Demak District
Authors: Sadullah Akhmad , Kristiyanto Agus , Purnama Sapta Kunta 
Published: June 2020

AbstractThe background of this research is the unavailability of learning model of basic technique of hand ball which is used as a reference to build the ability of basic technique of hand ball among the students. The purpose of this research is to develop the basic technique of handball based technique of handball based on adobe flash player, including opening, passing, catch the ball, dribble, blocking, shoot the ball, goalkeeper training and stretching, all of which are arranged in one easily accessible media anytime, by anyone and anywhere, especially at the Se-degree Junior High School in Demak district. The research method used is "Reasearch and Developement" approach. "This research is a research and development through preliminary stage, development of learning design, production, and product evaluation. After the production phase, then the initial product validation stage by media experts, academicians and practitioners. The evaluation results of media experts for the assessment component containing aspects of text, images / photos, sound audio, video obtained 61% of the total for the feasibility conclusion of the product. The results of the evaluation of academicians for the assessment component containing aspects of conformity, usefulness, security, and aspects of implementation are 85.71% of the total for the feasibility conclusion of the product. The results of the expert evaluation of practitioners for the assessment component containing aspects of conformity, usefulness, security, and the implementation aspect obtained 97.86% of the total for the feasibility conclusion of the product. The final percentage of all experts is 81.58% and it can be interpreted that the design of Adobe Flash Player based hand baseball technique technique can be tested in the next step. Small group test results for the assessment component that contains aspects of conformity, usefulness, security, and aspects of implementation obtained 71.25% of the overall for the feasibility of the conclusion of the product. The results of the large group test for the assessment component that contains aspects of conformity, usefulness, security, and the implementation aspect obtained 87.92% of the overall for the feasibility conclusion of the product. Based on the specified criteria it can be concluded that Adobe Flash Player's handmade basic ballast technique technique products are valid and usable. This is because the data results are stretched 80 - 100% for clarification of product feasibility percentage. Therefore this product is feasible and effective to develop the extracurricular handmade coaching in Demak Regency. Keywords: Multimedia Learning, handball, adobe flash player
Hubungan Waktu Reaksi Kognitif dengan Prestasi Pencak Silat Atlet PELATDA Jawa Barat
Authors: Irawan Irawan - , Mahendra Agus , Mulyana Mulyana 
Published: June 2020

Abstrak_________________________________________________________ Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan yang signifikan antara waktu reaksi kognitif, dengan prestasi pencak silat atlet PELATDA Jawa Barat 2019. Metode penelitian yang digunakan adalah metode deskriptif dengan teknik korelasional. Populasi dan sampel yaitu atlet PELATDA pencak silat sebanyak 17 atlet dengan menggunakan teknik total sampling. Instrumen yang digunakan yaitu tes waktu reaksi kognitif dan skor hasil penelusuran prestasi atlet. Hasil penelitian menunjukan bahwa terdapat hubungan yang signifikan antara waktu reaksi kognitif dengan prestasi pencak silat atlet PELATDA Jawa Barat 2019. Khususnya terdapat hubungan yang signifikan bagi atlet yang mempunyai prestasi yang tinggi terhadap waktu reaksi kognitif.. Abstract_________________________________________________________ This study aims to determine whether there is a significant relationship between cognitive reaction time, with the achievement of martial arts athletes PELATDA West Java 2019. The research method used is descriptive method with correlational techniques. Population and sample were 17 PELAT silat martial arts athletes using total sampling techniques. The instruments used were cognitive reaction time tests and athletes' achievement tracking results. The results showed that there was a significant relationship between cognitive reaction time with martial arts achievements of PELATDA West Java athletes in 2019. In particular there was a significant relationship for athletes who had high achievement on cognitive reaction time..
Bagaimana Motivasi Olahraga Mahasiswa di Papua?
Authors: Putra Miftah Fariz Prima 
Published: June 2020

Penelitian ini memiliki tujuan untuk mengungkap bagaimana motivasi olahraga mahasiswa yang ada di Papua. Jenis penelitian yang digunakan adalah survai dengan partisipan mahasiswa sebesar 88 orang (41 laki-laki dan 47 perempuan) dan rata-rata umur responden adalah 20,65 (SD: 2,4). The Sport Motivation Scale digunakan untuk mengambil data penelitian. Analisis deskriptif seperti nilai rata-rata, nilai terendah dan tertinggi, serta standar deviasi akan digunakan dalam studi ini. Hasil penelitian menemukan dimensi motivasi olahraga mahasiswa di Papua yang paling tinggi adalah intrinsic motivation-to experience stimulation (22,99), sedangkan yang paling rendah adalah amotivation (13,70). Motivasi olahraga internal lebih mendominasi dalam diri mahasiswa di Papua dibanding dengan eksternal dan dismotivasi.The purpose of this study was to reveal the sport motivation on the student sports in Papua. The survey research will be used in this study by involving 88 student as the sample (41 male and 47 female) and the average age of the respondents was 20,65 (SD: 2.4). Data was collected using The Sport Motivation Scale. Descriptive analysis such as mean value, lowest and highest value, and standard deviation will be used in this study. The results found the highest dimension of student sports motivation in Papua was intrinsic motivation-to experience stimulation (22.99), while the lowest was amotivation (13.70). Internal sports motivation is more dominant in students in Papua compared to external and motivated.
Correlation between Ambient Seismic Noises and Economic Growth
Authors: Hong Tae-Kyung , Lee Jeongin , Lee Giha , Lee Junhyung , Park Seongjun 
Published: June 2020

AbstractHuman activity is a major source of high-frequency seismic noise. Long-term ambient seismic noise levels and their influencing factors are investigated. The diurnal seismic noise level in 5–15 Hz display high correlation with human activities including traffic and industrial operations that are related to economic conditions. The temporal noise-level variations are consistent among three components. Analysis with seismic noises in three consecutive months of each year enables us to estimate the noise levels without seasonal effects. The daytime seismic noise-level changes in major cities of 11 countries are assessed using the 3 month records for decades. The annual seismic noise levels present strong correlations with gross domestic product (GDP), particularly with manufacturing and industrial GDP. The seismic noise levels increase quickly with GDP in low-GDP regions but slowly in high-GDP regions. This is because high-GDP regions already have large volumes of existing noise-inducing sources and because added sources contribute weakly. The seismic noise levels increased by 14%–111% for 5–23 yr depending on the economic conditions. The correlation between ambient seismic noise level and economy growth is a global feature. The high-frequency noise level may be a proxy to present the economic condition. Economic growth affects the Earth environment in a wide range of aspects.
TINGKAT KEPEDULIAN IBU TENTANG LITERASI MEDIA ANAK USIA DINI BERDASARKAN GEOSOSIAL
Authors: Munawarah Izzatul , Samawi Ahmad , Aisyah Eny Nur 
Published: June 2020

Mother's concern for good and correct media literacy for early childhood is very important. This attitude can also be analyzed for high and low levels and sought for differences if seen from geosocial factors. Researchers examined mothers based on significant differences between villages and cities in Malang. The research method used is comparative quantitative research. The comparative test in this study used the Independent T-Test which calculations using Microsoft Excel 2010 for Windows 10. The results of a comparative test with a total of 80 samples showed the conclusion that the level of maternal concern for AUD media literacy was not influenced by geosocial. But there are differences in the percentage of each aspect of the caring factor that needs to be considered, namely the highest percentage is in the aspect of understanding while the habituation aspect becomes the lowest aspect of the percentage. Although not influenced by geosocial factors, this can be one of the new problems for other researchers to further examine the causes and solutions of the inconsistencies between aspects of understanding and habituation in the attitude of maternal care for media literacy in early childhood.Kepedulian ibu dalam literasi media yang baik dan benar bagi anak usia dini adalah sangat penting. Sikap ini juga dapat dianalisis tingkat tinggi rendahnya serta dicari perbedaannya jika dilihat dari faktor geososial. Peneliti meneliti para ibu berdasarkan perbedaan signifikan antara desa dan kota di Malang. Adapun metode penelitian yang digunakan adalah penelitian kuantitatif komparatif. Uji komparasi dalam penelitian ini menggunakan Independent T-Test yang penghitungannya menggunakan Microsoft Excel 2010 for Windows 10. Hasil dari uji komparasi dengan total 80 sampel menunjukkan kesimpulan bahwa tingkat kepedulian ibu terhadap literasi media AUD tidak dipengaruhi oleh geososial. Namun terdapat perbedaan persentase pada setiap aspek dari faktor kepedulian yang perlu diperhatikan yaitu persentase tertinggi ada pada aspek pemahaman sedangkan aspek pembiasaan menjadi aspek yang terendah persentasenya. Meskipun tidak dipengaruhi oleh faktor geososial, hal ini dapat menjadi salah satu permasalahan baru bagi peneliti lain untuk diteliti lebih lanjut penyebab maupun solusi dari ketidaksinkronan antara aspek pemahaman dengan pembiasaan dalam sikap kepedulian ibu terhadap literasi media anak usia dini.
To study the effect of iv dexmedetomidine versus iv labetalol for the suppression of sympathoadrenal response to extubation
Authors: S Sindhu , Srinivas V Y 
Published: June 2020

Tracheal extubation evokes various degrees of disturbances in the autonomic nervous system in the form of tachycardia, hypertension which can cause deleterious consequences in susceptible patients.Hence this study was conducted between iv Dexmedetomidine and iv Labetalol to compare their effectiveness in the suppression of haemodynamic response to tracheal extubation.60 participants aged between 18-55 yrs belonging to ASA 1 or 2 were randomly allocated into 2 groups. Group Dd received injection Dexmedetomidine 0.6mcg/kg iv and Group Ll received injection Labetalol 0.25mg/kg body weight. Heart rate, systolic and diastolic blood pressure were recorded at baseline, 2,5,8 minutes after drug infusion, at extubation and 1,3,5,8,10 and 15 minutes post extubation.Group Dd showed a better decrease in heart rate, systolic and diastolic blood pressure at extubation, and 15 minutes post extubation compared to Group Ll.Injection Dexmedetomidine 0.6µg/kg showed a better attenuation of sympathoadrenal response to extubation compared to injection Labetalol 0.25mg/kg.
Bolus dose versus fractionated dose injection of hyperbaric bupivacaine in spinal anaesthesia among adult patients undergoing lower limb surgery: A prospective study
Authors: Ahluwalia Pallavi , Srivastava Nakul , Jheetay G S , Singh Gurpartap 
Published: June 2020

Spinal anaesthesia (SA) with bolus dose has rapid onset but rapid onset may precipitate hypotension. If local anaesthetic is injected in fractions with some time gap, it may provide dense block with haemodynamic stability and prolonged duration of analgesia. We aimed to compare bolus dose with fractionated dose in SA for haemodynamic stability and duration of analgesia in patients undergoing lower limb surgery. After the Institutional Ethics Committee clearance, the study was carried out in sixty patients undergoing lower limb surgery. Patients were divided into two groups. Group B patients received single bolus SA with injection bupivacaine heavy (0.5%), 3 ml and Group F patients fractionated dose with two-third (2ml) of the total dose of injection bupivacaine heavy (0.5%) given initially followed by one- third (1ml) dose after 90s. Time of onset and regression of sensory and motor blockage, intraoperative haemodynamics and duration of analgesia were recorded and analysed with Student’s unpaired t-test. Result: Patients were more haemodynamically stable in Group F as compared to Group B. Five patients in Group F and ten patients in Group B required vasopressor. Duration of sensory and motor block and duration of analgesia were longer in Group F compared to Group B. Fractionated dose of SA provides greater haemodynamic stability and longer duration of analgesia compared to bolus dose.
Comparison of dexmedetomidine with ketamine for their effects on amplitude of motor evoked potential intraoperatively
Authors: Soni Vibha , Sachdev Sudhir , Sisodia Ravindra , Jethava Durga 
Published: June 2020

Intraoperative motor evoked potential monitoring is commonly used during spinal surgeries as it reduces incidence of neurological damage and have better post-operative neurological outcome. Anaesthetic agents cause a dose dependent inhibition of evoked potential responses while ketamine and dexmedetomidine are said to have minimal effect. We planned this study to compare effect of dexmedetomidine and ketamine on MEP.All patients induced using glycopyrrolate, fentanyl, propofol and no anxiolytics and intubated with succinylcholine 2mg /kg, maintenance done with propofol infusion@ 60 mg/hr in both groups. Group-D- received dexmedetomidine 0.5mg/kg and Group-K- received ketamine 0.6mg/kg in 100ml NS over a period of 10mts.Electrodes were placed above the level of surgical intervention for MEP and TOF recording. Baseline MEP recorded and after completion of infusion of the study drugs was taken as 0 min, then the MEP was recorded at every 5 min till 30 min.In our study we observed that amplitude of MEP was statistically significant (p value 0.009 at 15 minutes) and was higher in ketamine group than dexmedetomidine group.We concluded that both agents are equally good as they cause minimal depression and are equally efficient in measuring the amplitude of MEP.
The Progress of Composites with High Thermal Conductivity and Electromagnetic Shielding
Authors: Liu Houbao , Fu Renli , Dong Weisong , Song Yingjie , Zhang Hao 
Published: June 2020

<p>As electronic components develop toward high power, high package density, and device size miniaturization, heat dissipation and electromagnetic interference between electronic components are becoming more and more serious. In order to solve the adverse elec tromagnetic waves and heat radiation generated by electronic devices, people have high hopes for electronic packaging materials with high thermal conductivity and electromagnetic interference resistance. This paper summa rizes the research status of high thermal conductivity composite materials and electromagnetic shielding composite materials. Finally, the latest research results of high thermal conductivity and electromagnetic shielding composites are introduced, and the future development trend of new materials for microelectronic packaging is prospected.</p>
Matlab® Algorithm to Simulate the Dynamic Behavior of an NiTi Alloy through Ansys® APDLTM Models
Authors: César Hilário Jean , Braz-Cesar Manuel , Andrade Carlos , Silva Borges Adailton 
Published: June 2020

In recent years, technological advances related with the so-called intelligent materials have been exploited for problem solving in many engineering fields. In this regard, shape memory alloys (SMA) seem suitable for medical and engineering applications and many others. These alloys have the ability to return to the original form after an apparently plastic deformation by applying heat and the also ability to perform phase changes with voltage variations under a specific temperature. These properties allow the development of a hysteretic loop with energy dissipation, which can be used as a damping element in a vibratory system. In this paper, a MATLAB algorithm was developed to create an interface with the Ansys® APDLTM software that simulate the dynamic behavior of a SMA. The software is capable to obtain the cyclical behavior of a vibratory mechanical system based on the energy dissipation properties of the SMA. The results show that the free vibration of a mass-damper (alloy) system presents the energy dissipation related in magnitude with the area of the hysteresis loop until the deformation caused by the motion which does not correspond to a voltage required to initiate the (direct) phase transformation of the material, thus reducing the displacement to a constant level.
Keywords: SMA, ANSYS APDLTM, Matlab
Hexagonal Zones in Transport Demand Models
Authors: Chmielewski Jacek , Kempa Jan 
Published: June 2020

Planning the development of transport systems, as well as assessing the effects of investment activities in the field of spatial development requires the use of appropriate IT tools enabling an objective assessment of investment intentions. In the field of transport analysis, one such tool is a transport demand model. Reproduction of transport-related processes is the main role of such transport demand model. This applies to both the transport of people and goods, and includes both residential travel and visitors travelling to and within the study area. The description of the process of creation and implementation of transport demands is usually based on the assumptions in the field of places of generation and absorption of travel - i.e. sources and destinations of travel. The generalization of the mathematical description of this phenomenon introduced the concept of transport zones, which are separated homogeneous areas of the study area, as sources and destinations of trips. Practice in the construction and use of transport models indicates that the problem of defining transport zones requires further investigation. Increasingly extensive transport infrastructure data collected in open databases (such as OpenStreets) are encouraging a change in the approach to the problems of constructing transport zones. The current solutions are characterized by a high level of generalization of sources and destinations rather than detailed transport analysis. This article presents the author’s method of dividing the study areas into transport zones based on a uniform hexagonal system, explaining the basic assumptions and evaluating the pros and cons of this proposed system.
Keywords: Transport, Demand models, Algorithms
Organizational and Methodological Influence of Risk Management in Projects
Authors: Francisco Gomes Diogo , Martins da Eira Dias Ana Sofia , João Feliciano Pina da Costa Abreu António , Victorovna Guitiss Navas Helena 
Published: June 2020

Project risk management is essential to managers’ decision making and business success, because it allows the manager to identify, analyse and decide on the most appropriate way to respond to different adversities that may arise during the development of new products, services, processes, projects, continuous improvement, etc. This requires a mind-set that risks have a major influence on the bottom line and use analytical methods or risk management software. It is essential to integrate the entire organizational structure into risk mitigation intervention. The purpose of this paper is to address some of the important topics to consider for well implemented and successful risk management. An approach is taken at both organizational and methodological levels.
Keywords: Risk management, PMBOK, Stakeholders, Methods, New product development