bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of effect of brainstem evoked response audiometry in hyperlipidemic patients
Authors: Senniappan Shivakumar , Paramasivam Gowri 
Published: October 2020

<p class="abstract"><strong>Background:</strong> Brain stem evoked response audiometry (BERA) is a useful objective assessment of hearing. The major advantage of this procedure is its ability to test even infants in whom conventional audiometry may not be useful. This investigation can be used as a screening test for deafness at high risk. This study is to correlate changes in brainstem evoked response audiometry parameters concerning lipid profile.</p><p class="abstract"><strong>Methods:</strong> The study was conducted between January 2019 to June 2020 on 50 patients attending ENT OPD in Vinayaka Mission’s Kirupanandha Variyar Medical College and Hospital, Salem. All patients with auditory and/or vestibular complaints were seen at the otorhinolaryngology OPD and underwent an otorhinolaryngological examination, audiological studies (pure tone audiometry) and an electrophysiological assessment BERA. </p><p class="abstract"><strong>Results:</strong> The results of BERA was considered. A total of 5 waveforms and 3 interpeak latency waves were calculated. It was recorded from both the ears. There was a significant increase in the values of absolute waves II, III, IV, and V and interpeak latency wave values I-II and I-V.</p><p class="abstract"><strong>Conclusions:</strong> Early identification of hyperlipidemic patients is useful in preventing disease progression and associated morbidity and mortality. BERA is a non-invasive method which can help us to detect central auditory pathway dysfunction at early stages in hyperlipidemic patients even before the patient's experience symptomatic hearing loss.</p>
MODERN PROBLEMS AND ASSESSMENT OF THE EFFECTIVENESS OF THE STATE SOCIAL POLICY AND SOCIAL SECURITY OF THE POPULATION
Authors: Oteshova Almagul , Prodanova Natalia , Niyazbayeva Aigul , Savina Natalia , Dikikh Vadim 
Published: October 2020

Purpose of the study: This article aims to analyze the theoretical and practical issues of public administration in the social sphere in a market economy; to consider the implementation of social programs of the Republic of Kazakhstan. Recommendations were also made to assess areas for improving the social system. Special attention is paid to the analysis of political activities and policies in all spheres of society.
Methodology: The study was based on the analysis of the development of social sectors in a market economy and evaluated the directions for improving the system of social sectors in a market economy. General scientific methods of cognition-dialectical, analysis, synthesis, system and functional approaches, generalization, comparison, analogy; methods of empirical research have been employed for this study.
Main Findings: In the article were studied and suggested ways to support the poor and low-income segments of the population, help them find employment in society, reduce the level of crime in society, develop social spheres (education, health, science, culture, residential homes, etc.), and ensure the country's environmental security.
Applications of this study: The results of the study can be used by public authorities in the development and implementation of policies in the field of social protection and income regulation, population and development, gender, and family policy.
Novelty/Originality of this study: The study includes the development of theoretical foundations of social protection of the population, taking into account the current rules of economic social dynamics; the development of a model for the implementation of social protection of the population related to the justification of parameters of its demographic effectiveness and the justification of new directions and practical recommendations in the development of methodological approaches for the development of social protection of young families.
THE ASSISTANCE OF THE REPUBLIC OF KAZAKHSTAN IN CONFLICT RESOLUTION IN THE SOUTH CAUCASUS
Authors: Raiymbekova Akerke , Yermekbayev Adilbek , Shukyzhanova Aiym , Nassyrova Madinyam , Zhabina Zhansaya 
Published: October 2020

Purpose of the study: The study aims to show that name is a kind of social identification code, i.e., the names serve essential social and legal functions that contribute to identifying the person in society, allowing joining various social institutions. The functioning of personal names plays a significant role in the lives of every member of the community.
Methodology: The main methodological approaches are determined using domestic and foreign researchers' fundamental works in political, historical, and economic science. A comparative historical analysis was used to determine the main stages and trends in the development of relations between the main actors in the framework of the Karabakh crisis.
Main Findings: Kazakhstan’s diplomacy is able to solve the problem of relations between Armenia and Azerbaijan, thereby ensuring security in the region for further implementation of the policy of diversification of energy supplies to the European market. The difficulty lies in the fact that both Armenia and Azerbaijan are strategic partners of Kazakhstan.
Applications of this study: This research is scientifically and practically important. It contributes to developing the theoretical aspect of scientific research on the model of mediation policy of Kazakhstan and its application in achieving international stability in the South Caucasus region. The authors showed the consideration of the problems of the global efforts of Kazakhstan in resolving the Nagorno-Karabakh crisis.
Novelty/Originality of this study: This study fully reveals the understanding of Kazakhstan's activities and the extent to which the official Nur-Sultan uses diplomatic efforts to resolve the international conflict in the Caucasus. This study examines the conditions, means, methods, and tools adopted by Kazakh diplomats to achieve stability and peace in the region.
CAUSES OF MODERN COUPS AND CONSIDERATION OF FACTORS AFFECTING THE ESCALATION OF THE POLITICAL CRISIS IN ARAB COUNTRIES
Authors: Kurpebayeva Gaziza 
Published: October 2020

Purpose of the study: The article describes the comparative analysis of the main parameters of the Arab Spring Revolution. The Arab world is the ethnic core of the Middle East. These countries faced an acute problem of choosing their political strategy. Globalization has largely discounted the idea of national sovereignty and a self-sufficient economy with the leading role of the public sector.
Methodology: The main methodological approaches are defined using the basic principles reflected in leading researchers' works in political, historical, and social sciences. The complete application of comparative historical analysis allowed us to determine the main stages and trends in developing political processes within the "Arab spring" framework. The use of modeling and forecasting methods allows determining options for further development of these processes.
Main Findings: The Middle East and North Africa took part in the forced revolutionary transformation of political regimes, called the Arab spring. The growth of protests in the region is due to internal and external reasons. Each country depends on the specific socio-political, economic, religious situation, and the characteristics of states' historical development.
Applications of this study: Based on the results of this study, it is possible to develop new recommendations for the foreign ministries of countries that are neutral in relation to the processes of socio-political transformations in the Arab countries.
Novelty/Originality of this study: This study is one of the first attempts to consider the socio-political processes that took place in the countries of the Arab East through the prism of Kazakh diplomacy, as a country that does not have certain geopolitical goals and benefits, as a country that does not have a direct or indirect relationship to the events of the Arab spring.
Effect of strains from different <i>Saccharomyces</i> species used in different inoculation schemes on chemical composition and sensory characteristics of Sauvignon blanc wine
Authors: Dimopoulou Maria , Troianou Vicky , Toumpeki Chrisavgi , Gosselin Yves , Dorignac Étienne , Kotseridis Yorgos 
Published: October 2020

Enhancing the sensory profile of wine using different microorganisms has always been a challenge in winemaking. The aim of our work was to evaluate the impact of different fermentation schemes by using mixed and pure cultures of three different Saccharomyces species at classic and cold inoculation temperatures on wine chemical composition and sensory profile. All the produced wines were analysed for the main oenological parameters (total acidity, volatile acidity, residual sugars, alcohol, and malic acid), as well as for volatile aromatic compounds, such as higher alcohols, acetate esters, ethyl esters and varietal thiols. In addition, implantation monitoring at the strain level and sensory analyses were performed in all fermentation trials. The wines fermented with S. pastorianus strains were characterised by significant lower acetic acid production and greater malic acid degradation compared to the wines fermented with S. cerevisiae strains. Interestingly, when the inoculation process for all trials was performed at a cold temperature (13 °C), the typical aromas of Sauvignon blanc were stronger than those in the classic inoculation temperature (18 °C) trials. Furthermore, the co-inoculation of S. pastorianus and S. bayanus resulted in wines exhibiting a higher intensity of citrus fruit notes than the wines fermented with the commercial S. cerevisiae strains. These results show that some strains from different Saccharomyces species other than S. cerevisiae, such as S. pastorianus and S. bayanus, could be promising starters for Sauvignon blanc wines and their performance can be modulated by the inoculation conditions.
Results of Detecting SARS-CoV-2 and Other Pathogens of Community-Acquired Pneumonia by PCR in the Tyumen Region
Authors: Bakshtanovskaya I. V. , Stepanova T. F. , Sharukho G. V. , Letyushev A. N. , Stepanova K. B. , Loginova N. V. , Panina Ts. A. , Zmatrakova E. A. , Kosyreva A. N. , Bartusevich A. Z. , Leont’eva S. A. , Vishnyakova A. O. 
Published: October 2020

The aim of this work was to identify the causative agent of community-acquired pneumonia and coinfection using PCR study of biomaterial from patients.Materials and methods. PCR testing of 268 samples from 258 patients was carried out to identify RNA/DNA of viral and bacterial pathogens of respiratory infections.Results and discussion. In 43.3 % of samples SARS-CoV-2 RNA was detected, in 4.5 % – RNA/DNA of acute respiratory viral infections pathogens, in one sample – DNA of Mycoplasma pneumoniae. Co-infection was detected only in patients of the anti-tuberculosis dispensary (SARS-CoV-2 and Mycobacterium tuberculosis). In the examined patients with pneumonia, SARS-CoV-2 RNA was significantly more often detected in biomaterial from the lower respiratory tract (52 %) than in respiratory smears (8.5 %). In the first week from the onset of the disease, 19.2 % of positive samples were found, in the second – 56.5 %.
Comparative Proteomic Profiles of Typical Strain and Genetically Altered Variant of Vibrio cholerae O1, Biovar El Tor
Authors: Zadnova S. P. , Badanin D. V. , Plekhanov N. A. , Polunina T. A. , Kotova N. V. , Kritsky A. A. , Fedorov A. V. , Krasnov Ya. M. 
Published: October 2020

Objective of the study was to identify the differences in the production of proteins in typical strain and genetically altered variant of V. cholerae O1, biovar El Tor.Materials and methods. Natural strains M1062 (Astrakhan, 1970) and M1509 (Moscow, 2010) were used as model strains in this work. Strains were cultivated on Luria Bertani agar at 37 °C. Electrophoresis was performed in accordance with W.K. Laemmli technique (1970), mass-spectrometric profiling – the method described by A. Shevchenko et al.Results and discussion. Mass-spectrometric scanning of cell lysates of the examined strains showed significant similarity of their proteomes (615 common proteins). The identified differences pertained to high expression of proteins in the strain M1062, participating in biosynthesis of DNA/RNA, included into “purines, pyrimidines, nucleosides” group, as well as regulatory proteins. In M1509 strain, biosynthesis of the proteins responsible for pathogenesis, adaptation under the influence of unfavorable environmental factors, included into “co-factors, vitamins, pigments” group, involved in lipid, carbohydrate, and protein metabolism, cellular processes, as well as proteins-transporters was increased. It has been suggested that the wide dissemination of El Tor genovariants is probably due to enhanced pathogenic and adaptive properties and also to the considerable transformation of cell metabolism.
Characteristics of Bacterial Microflora Isolated from Sputum of Patients with Pneumonia Registered in Khabarovsk City and Khabarovsk Territory in the Initial Period of COVID-19 Pandemic in May–June, 2020
Authors: Bondarenko A. P. , Shmylenko V. A. , Trotsenko O. E. , Kotova V. O. , Butakova L. V. , Bazykina E. A. 
Published: October 2020

Objective: to study the bacterial microflora in the sputum of patients with pneumonia caused by SARSCoV-2 or other pathogens.Materials and methods. The bacterial microflora of sputum of 173 patients with pneumonia admitted to hospitals in Khabarovsk and the Khabarovsk Territory in May – June 2020 was examined. Detection of RNA of the SARS-CoV-2 virus was carried out by PCR with the Vector-PCRRV-2019-nCoV-RG test system (manufactured by the State Scientific Center of VB “Vector”, Koltsovo). Determination of the DNA of mycoplasmosis agents and chlamydia was carried out with the test system “AmpliSens® Mycoplasma pneumoniae/Chlamydophila pneumonia” (manufactured by CRIE). Statistical data processing was performed using the Excel program. Results and discussion. Both groups of patients (Covid-19+ and Covid-19–) had high levels of bacterial flora isolation (81.4 and 74.7 %) including common pathogens for community-acquired pneumonia as well as notable detection frequency of Candida spp. and microbial associations. The group of Covid-19+ patients demonstrated a wider range of detected pathogens, was positive for poly-resistant gram-negative Enterobacteriaceae, non-fermenting gram-negative poly-resistant bacteria, with more expressed manifestation of microbial associations. In the group of Covid-19– participants drug-resistant microflora was presented only by MRSA and MRSE staphylococci.
The role of knowledge, risk perceptions, and cues to action among Iranian women concerning cervical cancer and screening: A qualitative exploration
Authors: Asl Rahim Taghizadeh , Osch Liesbeth Van , De Vries Nanne , Zendehdel Kazem , Shams Mohsen , Zarei Fatemeh , De Vries Hein 
Published: October 2020

Abstract
Background Iran has a low incidence but higher rate of death from cervical cancer (CC). The country is in the process of implementing an organized screening program including HPV testing and cytology. Studies show high dropout in continued testing among eligible women. This qualitative study aimed to explore women’s awareness regarding CC and CC testing and the role of knowledge, perceived risk, and cues to action in this process.MethodThrough a qualitative study based on the Framework Method, we recruited 81 women aged 25-65 who participated in 15 focus group discussions (FGDs) and two in-depth interviews in Tehran. The interviewees were selected purposefully during January to May 2015 from households belonging to different socioeconomic classes until data saturation. The data were acquired through 11 open-ended questions and 32 related probe questions. All interviews were transcribed and independently analyzed by two researchers (Kappa and agreement testing respectively: 0.77, 97.11%).ResultsThe coded texts were categorized under three themes and 13 subthemes. The three thematic areas referred to knowledge, cues to action, and perceived risks regarding CC and screening. The results showed that women had limited and unspecified knowledge about CC and screening, compounded by misconceptions regarding infection and cancer prevention measures. Social and cultural barriers hindered proper communication between health system/providers and clients and within communities on subjects related to CC and screening. The perceived risk of getting CC was low because of overestimating the role of hereditary factors for CC, difficulty in differentiating between cancer and sexually transmitted infections (STI), and the absence of visible symptoms.ConclusionThe results indicate a strong need to invest more efforts to improve health education and communication in the current national health program to promote awareness of the need to screen for CC through, for example, establishing correct knowledge and risk perceptions among women. In addition, this intervention should address women’s social environment in order to prevent misconceptions being communicated to women.
Occupational injuries, daily workload, and fitness levels among fitness and swimming instructors.
Authors: Bonato Matteo , Merati Giampiero , Agnello Luca , Grevers Dorothée , Maggioni Martina Anna 
Published: October 2020

Abstract
Background. Fitness (FI) and swimming instructor (SI) are two different type of trainers that are usually employed in fitness centers and their profession is highly physically demanding because they have to exercise while teaching. To date, data on occupational disorders in FI are limited and there is no information about SI. Therefore, the primary outcome of this study was an exploratory analysis of occupational disorders experienced by FI and SI employed in various fitness centers through a self-reported questionnaire, to provide first data on its prevalence. The secondary outcome was to assess fitness levels, workloads and perceived exertion during a typical working day of SI and FI in order to explore the possible factors associated with occupational disorders in these professional activities.Methods. An online cross-sectional survey addressing physical data, frequency, duration and time of class participation and self-reported occupational disorders was conducted among 435 subjects (FI=254; SI=179). Subsequently, 97 subjects (FI=57; SI=42), were enrolled to investigate physical fitness by maximal oxygen consumption (BO2max), and daily workload by heart rate (HR) and rating of perceived exertion (RPE).Results. A total of 621 musculoskeletal disorders and 521 of other disorders were included in the study with 157 and 155 participants that experienced 2 or more injuries during the last 2 years of their career, respectively. FI exhibited a higher prevalence of musculoskeletal injuries and SI experienced more upper respiratory tract infections. aO2max ranged from 47.0±4.0 to 51.9±3.7 ml·kg-1·min-1, and no statistically significant differences between sex and instructor type was found. No statistical differences between instructor type in HRmean and HRmean/HRmax was found. According to sex, female SI displayed significantly higher HRmean and HRmean/HRmax (p=0.018, p=0.022, respectively) than female FI.Conclusions. In conclusion, FI and SI experienced a high prevalence of musculoskeletal and occupational disorders. Moreover, data on FI and SI physical fitness and daily workload monitoring will help to set up guidelines regarding maximum weekly teaching load.
The potential of peer support to extend the reach of digital health
Authors: Nanton Veronica , Roscoe Julia , Appleton Rebecca , Clarke Amy , Dale Jeremy 
Published: October 2020

Abstract
BackgroundPeer support groups have proliferated since the 1960s, providing safe, informal environments where peers share experiences and information. A common model is for those who have progressed further along a care pathway or in dealing with a particular medical condition or psycho-social problem, to encourage those at an earlier stage of recovery, either within a group or one to one. Online support now co-exists with face to face models, providing an additional resource for those with digital access and competence.The paradigm of health care has moved towards the incorporation of health promotion, patient empowerment, self-management and community engagement. This has led to a broadening of activities and roles within health systems. The role of peer supporter has been incorporated in a range of behaviour change interventions promoting engagement and adherence. Increasingly these are delivered online. While this aims to extend their reach, it leaves those without digital access at a disadvantage in terms of the ability to make use of online health resources.Main textThough peer support has been used to maintain adherence to online programmes, its potential in assisting with access and thus widening participation has remained unknown.We successfully piloted the use of a paid peer supporter to help men without experience of IT to take part in an online intervention involving a prostate specific holistic needs assessment. Lessons were learnt in relation to training needs and support for the supporter and around data security, confidentiality and safeguarding.Alternative models of voluntary peer support maybe appropriate, particularly in the implementation phase of an intervention and require exploration. A framework for best practice in relation to Digital Health interventions is needed to guide future development of the role.ConclusionHealth services are predicted to increasingly rely on digital technologies over the next decade. Research into the impact of these technologies must include participants’ representative of the entire population. Efforts are needed to include those who are currently underrepresented in research such as the elderly and other disadvantaged groups. Innovative designs involving peer support in a research project may be valuable in addressing the current barriers to participation.