bluuebunny/crossref_metadata_2025_split huggingface dataset:
A viable system for carbon dioxide (CO2) methanation over fibrous silica ZSM-5 for substitute natural gas (SNG)
Authors: Hussain I , Jalil A A , Fatah N A A , Ibrahim M. , Azami M S , Fadlun W , Aziz M A H , Hambali HU 
Published: April 2020

Abstract
Catalytic CO2 methanation offers an attractive and sustainable way for the production of substituted natural gas (SNG), which may be used as a clean alternative energy source than fossil fuels. A metal-free fibrous silica ZSM-5 catalyst (FS@ZSM-5) was synthesized via the microemulsion technique to conduct catalytic CO2 methanation. The FESEM, BET, and FTIR characterization techniques were used to investigate the surface morphology, pore structure of the catalysts. It was noticed that the commercialized ZSM-5 showed 37% CH4 selectivity with a rate of methane formation 0.067 mmol m−2s−1. While FS@ZSM-5 exhibited high CH4 selectivity of 66 % with rate of methane formation 0.108 mmol m−2s−1 using same conditions (T = 500 °C and GHSV = 36,000 mL h−1 g−1). Therefore, the FS@ZSM-5 was proved an efficient and active catalyst for CO2 methanation activity.
Phytotoxicity Study of Native Plants in ex-mining lake water treatment
Authors: Draman S F S , Khalid S A , Sidek N M , Abdullah S R S , Anuar N 
Published: April 2020

Abstract
The use of phytoremediation in removing and degrade the contaminants gives great interest for researchers to explore further. This green technology is relatively eco-friendly and cost-effective. Before a full-scale system can be installed to ensure that the remedy is effective by selected plants using phytoremediation process, identification of these plants and its ability to resist toxicity of contaminants is crucial. In this study, the ability of native plants in Malaysia namely L. articulata, E. ochrostacys and E. dulcis to survive when exposed to acid mine drainage water (AMD) are investigated. This was done with free flow systems or free surface (FSF) for 30 days with water from ex mining lake, Tasik Puteri, Bukit Besi, Malaysia. The physical growth of those three plants such as height and withered leaves is monitored every seven day as indication of their survivability. Ferum (Fe) analysis is also carried out on the lower and upper part of the above three plants using Inductively Coupled Plasma – Optical Emission Spectrometry (ICP-OES). Results of the Fe analysis showed that E.ochrostacys has the highest accumulation ability compared to E.dulcis and L. articulata with a maximum accumulation of 123,584 mg Fe/kg at lower part and 55,151 mg Fe/kg at the upper part. Furthermore, E. ochrostacys was also able to tolerate and survive in the water of Tasik Puteri up to 80% survival rate during phytotoxicity study.
Parametric study of CO2 separation using carbon molecular sieve, zeolite and silica gel
Authors: Norani A A , Ahmad A , Abdullah T A T , Ripin A 
Published: April 2020

Abstract
Performances of Pressure swing adsorption (PSA) dependent on the type of adsorbent and efficiency of the regeneration cycle. In this work, a model describing CO2 mixture flow, mass and heat transfer with multi-component adsorption model are developed in Aspen Adsorption environment to compare the performance of PSA cycles with three different adsorbents (CMS 3K, zeolite 13x and silica gel). Adsorption capacity of CO2 for three adsorbents was found to be in the order of CMS>zeolite>silica gel. Hence, CMS was chosen as the adsorbents to evaluate PSA performances on different feed flowrate and pressure based on the purity, recovery and productivity of the CO2 separation. The result shows that, within a certain range, higher adsorption pressure will increase all purity, recovery and productivity of CO2 while higher feeding rate leads to increase recovery but lower purity and productivity.
Experimental Study of the Characteristics of Acoustic Cavitation Bubbles Under the Influence of Ultrasonic Wave
Authors: Hadi N A H , Ahmad A 
Published: April 2020

Abstract
Sonochemistry application in various fields, especially separation industries, are constantly increasing and extensively studied in recent years. In the applications, a detailed understanding of the characteristics and behaviour of acoustic cavitation bubble is crucial. However, acoustic bubbles behave differently in each liquid. Owing to numerous amounts of acoustic bubbles showing dramatic transition during sonication and have complex interaction in a liquid mixture, it is more difficult to observe acoustic bubble consistently and thoroughly. In response to this problem, our study will investigate separately acoustic cavitation bubble form in sonicated water, ethanol and mixture of ethanol-water. Each liquid was sonicated at 20 kHz ultrasound with a transducer attached to the bottom of an acrylic vessel. In order to visualise acoustic bubbles clearly, a high-speed video camera is used to capture the image of acoustic bubbles. Image processing and analysis are by the application of Image Processing Toolbox in MATLAB R2018b. Experimental result reveals that acoustic cavitation bubbles in a mixture of ethanol-water have the largest radius, volume and higher buoyancy force compared to pure ethanol and water. Results obtained coincided well with theory, which indicated that sonicated mixture containing alcohol provide resistance to gas transfer across liquid/bubble interface, leading to an increased bubble radius and hence the buoyancy force.
Investigation on the influence of tungsten particulate in mechanical and thermal properties of HD50MA180 high density polyethylene composites
Authors: E Jenson Joseph , Panneerselvam K 
Published: April 2020

Abstract
In this present investigation, the influence of reinforcing tungsten (W) particles in High- Density Polyethylene (HDPE) on mechanical and thermal properties, has been studied. W reinforced HDPE composites are processed by melt compounding method, with W varied in proportion of 1%, 3%, 5% and 7% by weight. The test specimens were prepared by injection molding as per ASTM standards and analyzed by X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), Mechanical and Thermal Characterization. XRD results show that, the intensity count at angle 40.3°, 58.7°, 73.6° and 87.1° increases with the increase in wt% of W particles. SEM analysis reveals that, composites containing 1wt% of W has uniform dispersion in the HDPE matrix. In mechanical characterization, tensile strength and flexural strength of the specimen reported a sharp increase with the addition of W at 1wt%, followed by a negative trend for the higher content of W particles. However, the impact strength result shows that specimen with 3wt% of W content has the highest toughness. Further from thermal characterization, Thermo Gravimetric Analysis (TGA) and Differential Scanning Calorimetry (DSC) results show that degradation temperature and the melting point of composites improve with an increase in W content. Composite with 7wt% W content has the highest degradation temperature and melting point.
Separated sets and Auerbach systems in Banach spaces
Authors: Hájek Petr , Kania Tomasz , Russo Tommaso 
Published: April 2020

The paper elucidates the relationship between the density of a Banach space and possible sizes of Auerbach systems and well-separated subsets of its unit sphere. For example, it is proved that for a large enough space

X
X

, the unit sphere

S
X

S_X

always contains an uncountable

(
1
+
)

(1+)

-separated subset. In order to achieve this, new results concerning the existence of large Auerbach systems are established, that happen to be sharp for the class of weakly Lindelöf determined (WLD) spaces. In fact, we offer the first consistent example of a non-separable WLD Banach space that contains no uncountable Auerbach system, as witnessed by a renorming of

c
0

(

ω
1

)

c_0(\omega _1)

. Moreover, the following optimal results for the classes of, respectively, reflexive and super-reflexive spaces are established: the unit sphere of an infinite-dimensional reflexive space contains a symmetrically

(
1
+
ε
)

(1+\varepsilon )

-separated subset of any regular cardinality not exceeding the density of

X
X

; should the space

X
X

be super-reflexive, the unit sphere of

X
X

contains such a subset of cardinality equal to the density of

X
X

. The said problem is studied for other classes of spaces too, including WLD spaces, RNP spaces, or strictly convex ones.
Learning transferable deep convolutional neural networks for the classification of bacterial virulence factors
Authors: Zheng Dandan , Pang Guansong , Liu Bo , Chen Lihong , Yang Jian 
Published: April 2020

Abstract

Motivation
Identification of virulence factors (VFs) is critical to the elucidation of bacterial pathogenesis and prevention of related infectious diseases. Current computational methods for VF prediction focus on binary classification or involve only several class(es) of VFs with sufficient samples. However, thousands of VF classes are present in real-world scenarios, and many of them only have a very limited number of samples available.

Results
We first construct a large VF dataset, covering 3446 VF classes with 160 495 sequences, and then propose deep convolutional neural network models for VF classification. We show that (i) for common VF classes with sufficient samples, our models can achieve state-of-the-art performance with an overall accuracy of 0.9831 and an F1-score of 0.9803; (ii) for uncommon VF classes with limited samples, our models can learn transferable features from auxiliary data and achieve good performance with accuracy ranging from 0.9277 to 0.9512 and F1-score ranging from 0.9168 to 0.9446 when combined with different predefined features, outperforming traditional classifiers by 1–13% in accuracy and by 1–16% in F1-score.

Availability and implementation
All of our datasets are made publicly available at http://www.mgc.ac.cn/VFNet/, and the source code of our models is publicly available at https://github.com/zhengdd0422/VFNet.

Supplementary information
Supplementary data are available at Bioinformatics online.
CircMiner: accurate and rapid detection of circular RNA through splice-aware pseudo-alignment scheme
Authors: Asghari Hossein , Lin Yen-Yi , Xu Yang , Haghshenas Ehsan , Collins Colin C , Hach Faraz 
Published: April 2020

Abstract

Motivation
The ubiquitous abundance of circular RNAs (circRNAs) has been revealed by performing high-throughput sequencing in a variety of eukaryotes. circRNAs are related to some diseases, such as cancer in which they act as oncogenes or tumor-suppressors and, therefore, have the potential to be used as biomarkers or therapeutic targets. Accurate and rapid detection of circRNAs from short reads remains computationally challenging. This is due to the fact that identifying chimeric reads, which is essential for finding back-splice junctions, is a complex process. The sensitivity of discovery methods, to a high degree, relies on the underlying mapper that is used for finding chimeric reads. Furthermore, all the available circRNA discovery pipelines are resource intensive.

Results
We introduce CircMiner, a novel stand-alone circRNA detection method that rapidly identifies and filters out linear RNA sequencing reads and detects back-splice junctions. CircMiner employs a rapid pseudo-alignment technique to identify linear reads that originate from transcripts, genes or the genome. CircMiner further processes the remaining reads to identify the back-splice junctions and detect circRNAs with single-nucleotide resolution. We evaluated the efficacy of CircMiner using simulated datasets generated from known back-splice junctions and showed that CircMiner has superior accuracy and speed compared to the existing circRNA detection tools. Additionally, on two RNase R treated cell line datasets, CircMiner was able to detect most of consistent, high confidence circRNAs compared to untreated samples of the same cell line.

Availability and implementation
CircMiner is implemented in C++ and is available online at https://github.com/vpc-ccg/circminer.

Supplementary information
Supplementary data are available at Bioinformatics online.
Contribution of the Entopeduncular Nucleus and the Globus Pallidus to the Control of Locomotion and Visually Guided Gait Modifications in the Cat
Authors: Mullié Yannick , Arto Irène , Yahiaoui Nabiha , Drew Trevor 
Published: April 2020

Abstract
We tested the hypothesis that the entopeduncular (EP) nucleus (feline equivalent of the primate GPi) and the globus pallidus (GPe) contribute to both the planning and execution of locomotion and voluntary gait modifications in the cat. We recorded from 414 cells distributed throughout these two nuclei (referred to together as the pallidum) while cats walked on a treadmill and stepped over an obstacle that advanced towards them. Neuronal activity in many cells in both structures was modulated on a step-by-step basis during unobstructed locomotion and was modified in the step over the obstacle. On a population basis, the most frequently observed change, in both the EP and the GPe, was an increase in activity prior to and/or during the swing phase of the step over the obstacle by the contralateral forelimb, when it was the first limb to pass over the obstacle. Our results support a contribution of the pallidum, in concert with cortical structures, to the control of both the planning and the execution of the gait modifications. We discuss the results in the context of current models of pallidal action on thalamic activity, including the possibility that cells in the EP with increased activity may sculpt thalamo-cortical activity.
First Mildly Ill, Nonhospitalized Case of Coronavirus Disease 2019 (COVID-19) Without Viral Transmission in the United States—Maricopa County, Arizona, 2020
Authors: Scott Sarah E , Zabel Karen , Collins Jennifer , Hobbs Katherine C , Kretschmer Melissa J , Lach Mitchell , Turnbow Katie , Speck Lindsay , White Jessica R , Maldonado Keila , Howard Brandon , Fowler Jeanene , Singh Sonia , Robinson Susan , Pompa Alexandra Peterson , Chatham-Stephens Kevin , Xie Amy , Cates Jordan , Lindstrom Stephen , Lu Xiaoyan , Rolfes Melissa A , Flanagan Marcy , Sunenshine Rebecca ,   for the Maricopa County COVID-19 Case Investigation Team
Published: April 2020

Abstract

Background
Coronavirus disease 2019 (COVID-19) causes a range of illness severity. Mild illness has been reported, but whether illness severity correlates with infectivity is unknown. We describe the public health investigation of a mildly ill, nonhospitalized COVID-19 case who traveled to China.

Methods
The case was a Maricopa County resident with multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–positive specimens collected on 22 January 2020. Contacts were persons exposed to the case on or after the day before case diagnostic specimen collection. Contacts were monitored for 14 days after last known exposure. High-risk contacts had close, prolonged case contact (≥ 10 minutes within 2 m). Medium-risk contacts wore all US Centers for Disease Control and Prevention–recommended personal protective equipment during interactions. Nasopharyngeal and oropharyngeal (NP/OP) specimens were collected from the case and high-risk contacts and tested for SARS-CoV-2.

Results
Paired case NP/OP specimens were collected for SARS-CoV-2 testing at 11 time points. In 8 pairs (73%), ≥ 1 specimen tested positive or indeterminate, and in 3 pairs (27%) both tested negative. Specimens collected 18 days after diagnosis tested positive. Sixteen contacts were identified; 11 (69%) had high-risk exposure, including 1 intimate contact, and 5 (31%) had medium-risk exposure. In total, 35 high-risk contact NP/OP specimens were collected for SARS-CoV-2 testing; all 35 pairs (100%) tested negative.

Conclusions
This report demonstrates that SARS-CoV-2 infection can cause mild illness and result in positive tests for up to 18 days after diagnosis, without evidence of transmission to close contacts. These data might inform public health strategies to manage individuals with asymptomatic infection or mild illness.
Chinese Investment Treaties in the Belt and Road Initiative Area
Authors: Sornarajah Muthucumaraswamy 
Published: April 2020

Abstract
This article examines whether Chinese practice towards the making of investment treaties with developing countries in the Belt and Road Initiative region will be different from the treaties that it makes with developed States. Though there is a shift towards the making of hard treaties with the developed States of Europe, it is suggested that treaties made with developing States will be more nuanced. The article shows that there are political motives behind investment treaties, as the study of US practice shows. Political considerations will induce China to make different types of treaties with different types of treaty partners in the future. A comparison is made with recent Indian practice.
Correlated structural evolution within multiplex networks
Authors: Wu Haochen , James Ryan G , D’Souza Raissa M 
Published: April 2020

AbstractMany natural, engineered and social systems can be represented using the framework of a layered network, where each layer captures a different type of interaction between the same set of nodes. The study of such multiplex networks is a vibrant area of research. Yet, understanding how to quantify the correlations present between pairs of layers, and more so present in their co-evolution, is lacking. Such methods would enable us to address fundamental questions involving issues such as function, redundancy, and potential disruptions. Here, we show first how the edge set of a multiplex network can be used to construct an estimator of a joint probability distribution describing edge existence over all layers. We then adapt an information-theoretic measure of general correlation called the conditional mutual information, which uses the estimated joint probability distribution, to quantify the pairwise correlations present between layers. The pairwise comparisons can also be temporal, allowing us to identify if knowledge of a certain layer can provide additional information about the evolution of another layer. We analyse datasets from three distinct domains—economic, political, and airline networks—to demonstrate how pairwise correlation in structure and dynamical evolution between layers can be identified and show that anomalies can serve as potential indicators of major events such as shocks.
Heritable arrhythmia syndromes associated with abnormal cardiac sodium channel function: ionic and non-ionic mechanisms
Authors: Rivaud Mathilde R , Delmar Mario , Remme Carol Ann 
Published: April 2020

Abstract
The cardiac sodium channel NaV1.5, encoded by the SCN5A gene, is responsible for the fast upstroke of the action potential. Mutations in SCN5A may cause sodium channel dysfunction by decreasing peak sodium current, which slows conduction and facilitates reentry-based arrhythmias, and by enhancing late sodium current, which prolongs the action potential and sets the stage for early afterdepolarization and arrhythmias. Yet, some NaV1.5-related disorders, in particular structural abnormalities, cannot be directly or solely explained on the basis of defective NaV1.5 expression or biophysics. An emerging concept that may explain the large disease spectrum associated with SCN5A mutations centres around the multifunctionality of the NaV1.5 complex. In this alternative view, alterations in NaV1.5 affect processes that are independent of its canonical ion-conducting role. We here propose a novel classification of NaV1.5 (dys)function, categorized into (i) direct ionic effects of sodium influx through NaV1.5 on membrane potential and consequent action potential generation, (ii) indirect ionic effects of sodium influx on intracellular homeostasis and signalling, and (iii) non-ionic effects of NaV1.5, independent of sodium influx, through interactions with macromolecular complexes within the different microdomains of the cardiomyocyte. These indirect ionic and non-ionic processes may, acting alone or in concert, contribute significantly to arrhythmogenesis. Hence, further exploration of these multifunctional effects of NaV1.5 is essential for the development of novel preventive and therapeutic strategies.
Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction
Authors: Kompa Andrew R , Greening David W , Kong Anne M , McMillan Paul J , Fang Haoyun , Saxena Ritika , Wong Raymond C B , Lees Jarmon G , Sivakumaran Priyadharshini , Newcomb Andrew E , Tannous Bakhos A , Kos Cameron , Mariana Lina , Loudovaris Thomas , Hausenloy Derek J , Lim Shiang Y 
Published: April 2020

Abstract

Aims
To establish pre-clinical proof of concept that sustained subcutaneous delivery of the secretome of human cardiac stem cells (CSCs) can be achieved in vivo to produce significant cardioreparative outcomes in the setting of myocardial infarction.

Methods and results
Rats were subjected to permanent ligation of left anterior descending coronary artery and randomized to receive subcutaneous implantation of TheraCyte devices containing either culture media as control or 1 × 106 human W8B2+ CSCs, immediately following myocardial ischaemia. At 4 weeks following myocardial infarction, rats treated with W8B2+ CSCs encapsulated within the TheraCyte device showed preserved left ventricular ejection fraction. The preservation of cardiac function was accompanied by reduced fibrotic scar tissue, interstitial fibrosis, cardiomyocyte hypertrophy, as well as increased myocardial vascular density. Histological analysis of the TheraCyte devices harvested at 4 weeks post-implantation demonstrated survival of human W8B2+ CSCs within the devices, and the outer membrane was highly vascularized by host blood vessels. Using CSCs expressing plasma membrane reporters, extracellular vesicles of W8B2+ CSCs were found to be transferred to the heart and other organs at 4 weeks post-implantation. Furthermore, mass spectrometry-based proteomic profiling of extracellular vesicles of W8B2+ CSCs identified proteins implicated in inflammation, immunoregulation, cell survival, angiogenesis, as well as tissue remodelling and fibrosis that could mediate the cardioreparative effects of secretome of human W8B2+ CSCs.

Conclusions
Subcutaneous implantation of TheraCyte devices encapsulating human W8B2+ CSCs attenuated adverse cardiac remodelling and preserved cardiac function following myocardial infarction. The TheraCyte device can be employed to deliver stem cells in a minimally invasive manner for effective secretome-based cardiac therapy.
Generalized Forecast Averaging in Autoregressions with a Near Unit Root
Authors: Kejriwal Mohitosh , Yu Xuewen 
Published: April 2020

SummaryThis paper develops a new approach to forecasting a highly persistent time series that employs feasible generalized least squares (FGLS) estimation of the deterministic components in conjunction with Mallows model averaging. Within a local-to-unity asymptotic framework, we derive analytical expressions for the asymptotic mean squared error and one-step-ahead mean squared forecast risk of the proposed estimator and show that the optimal FGLS weights are different from their ordinary least squares (OLS) counterparts. We also provide theoretical justification for a generalized Mallows averaging estimator that incorporates lag order uncertainty in the construction of the forecast. Monte Carlo simulations demonstrate that the proposed procedure yields a considerably lower finite-sample forecast risk relative to OLS averaging. An application to U.S. macroeconomic time series illustrates the efficacy of the advocated method in practice and finds that both persistence and lag order uncertainty have important implications for the accuracy of forecasts.