bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epstein Barr Virus in Hodgkin’s Lymphoma a Path Less Treaded: An Observational Study
Authors: Balhara Kirti , Singh Sarika , Jain Shyamlata , Daga M K , Vindal Anubhav 
Published: November 2020

Background: Epstein-Barr virus (EBV) is a ubiquitous virus belonging to γ-Herpesvirus subfamily, infecting B cells, T cells, Natural killer (NK) cells & causes both benign and malignant diseases. It has been detected in large subset of Hodgkin lymphoma (HL) cases around the world, especially in countries with poor socioeconomic conditions and among younger age. Limited studies are available reflecting the Indian scenario of HL and EBV association. EBV positivity in Indian HL varies from 28-97% Majority of these studies employed Immunohistochemistry (IHC) for LMP1, a few performed In Situ Hybridisation (ISH) for EBER.
Objective: To study the association of EBV in classical HL by immunohistochemical expression of latent membrane protein 1 (LMP1) antigen in North Indian population and to correlate it with different demographic variables & subtypes of HL.
Materials and Methods: Observational study including 26 untreated HL cases diagnosed on lymph node excision biopsy. IHC was performed for EBV LMP1, CD15, CD30, CD45, CD3, CD20.
Results: Patients ranged in age from 5-55years (median 18yrs), with M:F ratio of 3.3:1. Palpable lymphadenopathy was found in all cases followed by pallor (64%), B symptoms (50%), nodal pain (30.8%) & bulky disease (19.2%). Maximum number of patients were in Stage I (65.4%) followed by stage II&III (15.4% each) & stage IV (3.8%). Mixed cellularity HL comprised 77%, lymphocyte depleted 11.5%, nodular sclerosis 7.7% & lymphocyte rich 3.8%. IHC for EBV LMP1 was positive in 73.1% cases. Mixed cellularity HL showed an association in 70% cases.
Conclusions: HL in India is a disease of young males, with mixed cellularity as the commonest subtype, highly associated with EBV and presentation at an early stage.
Paediatric Eyelid Lesions- A Report of 20 Cases
Authors: Sathe Pragati , Asthana Ankita 
Published: November 2020

Background: Eyelid lesions are one of the commonest lesions encountered by ophthalmologists in their clinical practice. They could be classified in various ways such as neoplastic or non-neoplastic; congenital or acquired. The common benign conditions affecting the eyelid include cysts like dermoid, epidermoid and epithelial cysts, inflammatory lesions, melanocytic nevi and papilloma. Ignorance about the benign nature of the lesion may lead to increased debility.
The purpose of this study is to contribute information to the literature on various eyelid lesions and their incidence as found in a tertiary hospital.
Methods: This is a retrospective observational study of surgically excised eyelid lesions in patients below 12 years of age. The study was conducted after obtaining permission from the Institutional Ethics Committee.
Result: Out of 20 lesions, 15 cases belonged to the non-neoplastic category while five cases were neoplastic in nature. Cystic lesions predominated in the non-neoplastic category (11 out of 15 cases). The remaining four cases in the non-neoplastic category included three cases of infective etiology and one case of developmental etiology. There were no malignant neoplasms found in our study. The common presenting feature was that of eyelid swelling. Highest incidence of eyelid lesions was in the upper lid (14 of 20 cases, i.e. 66.66%).
Conclusion:
It is necessary to subject every lesion of the eyelid to histopathological examination. Sometimes, clinically benign lesions turn out to be malignancies which entails a wider surgery later. This study points out to the wide spectrum of lesions that can afflict the eyelid.
Analisis pelatihan online teknis big data menggunakan data logger Moodle
Authors: Kasmanto Rony 
Published: November 2020

AbstrakHasil pengamatan perilaku yang dilakukan pada peserta pelatihan daring dapat dijadikan bahan evaluasi untuk penyelenggaraan pelatihan pada masa yang akan datang menjadi lebih optimal. Penelitian ini bertujuan untuk mengetahui perilaku peserta, pengajar dan panita dalam proses pembelajaran dengan keseluruhan daring. Pendekatan penelitian adalah statistik deskriptif dengan menggunakan data logs report pada Learning Management System (LMS) Pusdiklat BMKG. Objek penelitian adalah 50 peserta pelatihan teknis big data yang berasal dari unit pelaksana teknis di BMKG, 13 pengajar dan 2 panitia. Pelatihan diselenggarakan di Pusat Pendidikan dan Pelatihan BMKG pada 28 Oktober sampai dengan 9 Desember 2019. Hasil penelitian menunjukkan bahwa perilaku pelaku pelatihan memiliki aktivitas yang signifikan hanya pada momen-momen tertentu. Sistem LMS mencatat beberapa kejadian: 1) terjadi peningkatan aktivitas peserta, ketika mendekati tenggang waktu pengumpulan semua tugas yaitu pada hari senin dan pada saat pelaksanaan post-test; 2) terjadi peningkatan aktivitas pengajar ketika mendapat peringatan dari panitia untuk pemberian grading terhadap semua tugas-tugas yang dikumpulkan peserta; 3) terjadi peningkatan aktivitas panitia pada saat agenda pembelajaran dimulai dan ketika pelaksanakan post-test. Analysis of big data technical online training using Moodle logger dataThe results of behavioral observations conducted on online trainees can be used as evaluation material for the implementation of future training to be more optimal. This research aims to find out the behavior of participants, teachers, and organizers in the process of full online learning. The research approach is statistically descriptive by using data logs report on Learning Management System (LMS) Pusdiklat BMKG. The research object was 50 big data technical trainees from the technical implementation unit at BMKG, 13 teachers and 2 committees. The training was held at BMKG Education and Training Center from October 28 to December 9, 2019. The results showed that the behavior of trainees had significant activity only at certain moments. The LMS system records several events: 1) there is an increase in participant activity, when approaching the grace period of all tasks that is on Monday and during post-test implementation; 2) there is an increase in teacher activity when it is alerted by the committee to grading all the tasks collected by participants; 3) there is an increase in committee activity at the time the learning agenda begins and when the implementation of post-test.
The role of character education in learning during the COVID-19 pandemic
Authors: Intania Enika Vera , Sutama Sutama 
Published: November 2020

Abstract Coronavirus Disease-2019 (COVID-19) has an impact on all aspects of life, including education. Face-to-face education must be transferred to online learning. In learning, both face-to-face and online, character education must always be instilled in students. Character education is an important thing that students must have in order to grow their character, so they can have good personalities In a pandemic such as now, character education is very necessary for students to continue to develop their potential, even though learning is carried out online. The purposes of this study are 1) Analyzing the role of character education in learning; 2) Describing the role of character education in learning in the pandemic era of COVID-19. This type of research is a reference research. The object of this research is the role of character education in learning in the COVID-19 pandemic era. Data validity is done by Triangulation of Sources and Triangulation of Extension. In this study, data analysis techniques used constant comparison. The results of the study are twofold, 1) Character education in learning has a role for students to foster good character that can be realized in their social life; 2) In the pandemic era COVID-19 character education can play a role so that students independently want to learn material and develop an attitude of responsibility towards the tasks given by the teacher in online learning. Peran pendidikan karakter dalam pembelajaran selama pandemi COVID-19Pandemi COVID-19 menimbulkan dampak pada semua aspek kehidupan, termasuk pendidikan. Pendidikan tatap muka harus dialihkan ke pembelajaran online. Dalam belajar, baik tatap muka maupun online, pendidikan karakter harus selalu ditanamkan pada siswa. Pendidikan karakter merupakan hal penting yang harus dilakukan siswa agar dapat menumbuhkan karakternya, sehingga mereka dapat memiliki kepribadian yang baik Di masa pandemi seperti sekarang, pendidikan karakter sangat diperlukan bagi siswa untuk terus mengembangkan potensinya, meskipun pembelajaran dilakukan secara online. Tujuan penelitian ini adalah, 1) Menganalisa peran pendidikan karakter dalam pembelajaran; 2) Menggambarkan peran pendidikan karakter dalam pembelajaran di era pandemi COVID-19. Jenis penelitian ini adalah penelitian referensi. Objek penelitian ini adalah peran pendidikan karakter dalam pembelajaran di era pandemi COVID-19. Validitas data dilakukan dengan Triangulasi Sumber dan Triangulasi Ekstensi. Dalam penelitian ini, teknik analisis data menggunakan perbandingan konstan. Hasil penelitian menunjukkan bahwa 1) Pendidikan karakter dalam pembelajaran memiliki peran bagi siswa untuk menumbuhkan karakter baik yang dapat diwujudkan dalam kehidupan sosialnya; 2) Di era pandemic, pendidikan karakter COVID-19 dapat berperan penting sehingga siswa secara mandiri ingin belajar materi-materi dan mengembangkan sikap tanggung jawab terhadap tugas-tugas yang diberikan guru dalam pembelajaran daring.
La estrategia editorial en torno al suceso: la invasión de Labort de 1636 en las imprentas hispanas
Authors: Ruiz Astiz Javier 
Published: November 2020

Las relaciones de sucesos narran todo tipo de acontecimientos, desde fiestas y entradas reales hasta casos extraordinarios, pasando por crónicas diplomáticas y militares. Durante la Guerra de los Treinta Años proliferaron este tipo de impresos dando noticia de asaltos y batallas, como la invasión que se produjo en 1636 de la zona de Labort. Este hecho se difundió rápidamente por la península ibérica en forma de relaciones de sucesos, conservándose cinco ediciones distintas impresas en cinco ciudades españolas. Todas narran el mismo suceso, aunque muestran diferencias paratextuales en portada y otros elementos tipográficos y ornamentales, así como en parte del texto. Esto nos habla de la estrategia editorial que siguió cada impresor, lo que se constatará a través del análisis material de cada una de las ediciones.
IN SILICO ANTIMALARIAL TARGET SELECTION CONSERVED IN FOUR PLASMODIUM SPECIES
Authors: AWofisayo Oladoja 
Published: November 2020

Objectives: The need for new antimalarials drugs and drug targets is pertinent due to the emergence of drug resistant strains of the parasites. Improper target selection has resulted in therapeutic failure. The genomic/post genomic era has made possible the deciphering of the 3D crystal structures of proteins and DNA which are drug targets and are deposited in the protein data bank.
Methods: Novel antimalarial targets obtained from evolutionary conserved short sequence motifs are utilised and are essential in transcription processes in the parasite. The motifs TGCATGCA, GTGCAC and GTGCGTGC were curated from experimental work, validated and analysed via phylogenomics genomics and comparative genomics. PlasmoDB blastn was applied to determine their similarity in Plasmodium vivax, knowlesi, Ovale and yoeli. The complete genome of Plasmodium falciparum vivax, knowlesi, Ovale and yoeli was downloaded from the plasmoDB and their positions determined.
Results: The targets are essential, conserved in rodent and mammalian species via phylogenomics with percentage identity and similarity greater than 80%, have no similar genes in the same genome and also found to be selective in the parasites vis-à-vis the Homo sapiens via comparative genomics with 0% identity and similarity in the human genome.
Conclusion: The targets reveal at the molecular and biochemical level, the vulnerable regions in the parasite while safe in human hence their choices in subsequent rationale drug discovery and design protocols.
Peer Review History:
Received: 18 July 2020; Revised: 1 October; Accepted: 12 October, Available online: 15 November 2020
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file

Average Peer review marks at initial stage: 5.5/10
Average Peer review marks at publication stage: 7.0/10
Reviewer(s) detail:
Dr. Tamer ELHABIBI, ERU University, Egypt, tamer_elhabibi@yahoo.com
Dr. Soroush Sardari, Biotech Pasteur Institute of Iran, Tehran, Iran, ssardari@hotmail.com
Comments of reviewer(s):

Similar Articles:
IN SILICO LIGAND-BASED 2D PHARMACOPHORE GENERATION FOR H+/K+ ATPASE INHIBITORS
SUDANESE EXPERIENCE OF HERBAL FORMULAS USED DURING COVID-19 INFECTION
Authors: Mohamed AzzaAbdelilah Ahmed , Humaida Mai Abdalla , Saeed Ali Awadallah 
Published: November 2020

Objectives: Corona virus disease 2019 (COVID-19) outbreak is recent worldwide disaster which is considered by the WHO as Public Health Emergency of International Concern (PHEIC).
Method: A quick survey was done in Khartoum state for the commonly utilize herbs and the succeeded formulas, 652 people participated in this survey either they use these herbs for themselves or their relative use it during the symptoms of COVID-19.
Results: A 652 people participated in the quick survey for the commonly utilized herbs & the succeeded formulas either they use these herbs for themselves or their relative use it during the symptoms of COVID-19. Other products used as additives include (honey,vinegar,sesame oil, olive oil and salt).
Conclusion: Sudanese experience that various traditional herbs, usage and different route of administration can effectively alleviate primary symptoms e.g. fever, cough, fatigue and reduce probability of developing severe Conditions.
Peer Review History:
Received: 8 September 2020; Revised: 7 October; Accepted: 20 October, Available online: 15 November 2020
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file

Average Peer review marks at initial stage: 5.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewer(s) detail:
Dr. Hebatalla Ibrahim Ahmed Abdel Hameed, Al-Azhar University, Faculty of Pharmacy (Girls), Nasr City, Cairo, Egypt hebatalla123@yahoo.com
Dr. Mohamed Derbali, Faculty of Pharmacy, Monastir, Tunisia, mohamed.edderbali@gmail.com
Comments of reviewer(s):

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THE RISKS AND ADVANTAGES OF ANTI-DIABETES THERAPY IN THE POSITIVE COVID-19 PATIENT
EUCALYPTUS ESSENTIAL OIL; AN OFF-LABEL USE TO PROTECT THE WORLD FROM COVID-19 PANDEMIC: REVIEW-BASED HYPOTHESES
METHOD DECISION FOR DETERMINING SPECIFIC MICROORGANISMS IN PHARMACEUTICAL PRODUCTS: AN OVERVIEW
Authors: CENGİZ Gökhan , YAPAR Evren ALGIN 
Published: November 2020

In the direction of microbiological quality control analysis in pharmaceutical products, determining the microbiological load of the product at the end-use stage is very important for human health. Quality control parameters in pharmaceutical products vary according to the structure of the type of product and administration route. In this context, according to the pharmacopoeias, parenteral products and eye drops are classified as sterile products and the other group of pharmaceuticals are classified as non-sterile products. However, non-sterile pharmaceuticals also must have a certain microbiological quality. For this reason, the pharmaceuticals should have a certain microbiological load and should not contain defined microorganisms specified to its type. Since the control of the microbiological quality of the products is important for safety, it should be determined by quality control analysis. In this study, standard methods used to detect specific microorganism in pharmaceutical products were compared. Application steps in standard methods and identification tests of specific microorganisms were examined. In addition, studies that are alternative to standard methods were evaluated.
Peer Review History:
Received: 5 September 2020; Revised: 20 October; Accepted: 28 October, Available online: 15 November 2020
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Received file

Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 8.0/10
Reviewer(s) detail:
Dr. Mujde Eryilmaz, Ankara University,Turkey, meryilmaz@ankara.edu.tr
Dr. Rawaa Souhil Al-Kayali, Aleppo University, Syria, rawah67@hotmail.com

Comments of reviewer(s):

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CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF THE ESSENTIAL OILS OF FOUR VARIETIES OF LIPPIA MULTIFLORA IN BENIN
ANTIMICROBIAL ACTIVITIES FOR HADHRAMI HONEY ON GROWTH OF SOME PATHOGENIC BACTERIA
Effect of Perception Differences in Money Communication Between Parent-Adolescents on Financial Autonomy: An Experimental Study Using Financial Education Workshops
Authors: Jariwala Harsha Vijaykumar 
Published: November 2020

This study evaluates the effect of parent-child money communication on financial autonomy of the adolescents by considering the gender of the parent as a controlled variable by utilizing pre- and post- survey based experimental research design. The sample consisted of 300 female parents and their children under adolescence stage of life. Assuming that claim is often made by parents regarding their frequent money communication with their children, their children were asked to rate their perception towards parent’s money communication with them. Later, their female parent (mother) were invited for financial education workshops series and asked to complete pre-survey before they attended the first financial education workshop. The follow-up survey was done for female parents and their adolescent children six months after completion of the financial education workshop series. In both the surveys, 300 responses were collected from female parents and adolescents on nineteen pairs of money communication, wherein parents were not told that their children were also asked to rate the matching pair of each item of parent money communication scale and vice versa. The financial autonomy was measured by using pre- and post- surveys, wherein only adolescents participated in the surveys. The results of paired t-test provides noticeable conclusion that financial education given to the parent positively enhances money communication among parent-adolescent by reducing the disparity in the responses collected from the parents and adolescents on each matched pairs separately and collectively and this reduced disparity leads to enhance the financial autonomy of the adolescents. The findings may help policy makers and financial educators to design and implement such workshops which may open lines of “money communication” between parents and children.
Key words: financial education workshops, parent-adolescent money communication, financial autonomy.
Mycobacterium Kansasii Infection Overlying Tattoo Pigment in an Immunocompromised Patient
Authors: Gupta Rohit , Martin Jennifer , Wasko Carina 
Published: November 2020

The incidence of atypical mycobacterial infections has steadily grown over the past decades, and it is well-known that the risk of progressive disease increases with immunodeficiency. While rare, tattoo pigment can serve as a nidus for atypical mycobacterium infection in immunocompromised individuals. Here, we present a case of a 41-year-old immunocompromised female who presented with verrucous plaques overlying long-standing tattoos in multiple locations. The patient’s lesions were biopsied and sent for board-range polymerase chain reaction revealing infection with Mycobacterium kansasii, a slow-growing atypical mycobacterium that rarely causes cutaneous disease without systemic symptoms. Early recognition and treatment of cutaneous M. kansasii is important to prevent progression of disease.