bluuebunny/crossref_metadata_2025_split huggingface dataset:
Noise and spectral stability of deep-UV gas-filled fiber-based supercontinuum sources driven by ultrafast mid-IR pulses
Authors: Adamu Abubakar I. , Habib Md. Selim , Smith Callum R. , Antonio Lopez J. Enrique , Uhd Jepsen Peter , Amezcua-Correa Rodrigo , Bang Ole , Markos Christos 
Published: March 2020

AbstractDeep-UV (DUV) supercontinuum (SC) sources based on gas-filled hollow-core fibers constitute perhaps the most viable solution towards ultrafast, compact, and tunable lasers in the UV spectral region, which can even also extend into the mid-infrared (IR). Noise and spectral stability of such broadband sources are key parameters that define their true potential and suitability towards real-world applications. In order to investigate the spectral stability and noise levels in these fiber-based DUV sources, we generate an SC spectrum that extends from 180 nm (through phase-matched dispersive waves - DWs) to 4 μm by pumping an argon-filled hollow-core anti-resonant fiber at a mid-IR wavelength of 2.45 μm. We characterize the long-term stability of the source over several days and the pulse-to-pulse relative intensity noise (RIN) of the DW at 275 nm. The results indicate no sign of spectral degradation over 110 hours, but the RIN of the DW pulses at 275 nm is found to be as high as 33.3%. Numerical simulations were carried out to investigate the spectral distribution of the RIN and the results confirm the experimental measurements and that the poor noise performance is due to the high RIN of the mid-IR pump laser, which was hitherto not considered in numerical modelling of these sources. The results presented herein provide an important step towards an understanding of the noise mechanism underlying such complex light-gas nonlinear interactions and demonstrate the need for pump laser stabilization.
Endovascular Mechanical Thrombectomy and On-Site Chemical Thrombolysis for Severe Cerebral Venous Sinus Thrombosis
Authors: Liao Chih-Hsiang , Liao Nien-Chen , Chen Wen-Hsien , Chen Hung-Chieh , Shen Chiung-Chyi , Yang Shun-Fa , Tsuei Yuang-Seng 
Published: March 2020

AbstractCerebral venous sinus thrombosis (CVST) is a rare cause of cerebral infarction. Once patients survive the acute phase, long-term prognosis is generally satisfactory. CVST patients who harbored risk factors known for poor prognosis (e.g., deterioration of consciousness/neurological functions and seizures) were oftentimes unresponsive to systemic heparin treatment. The advantage of combined endovascular mechanical thrombectomy (EMT) and on-site chemical thrombolysis (OCT) plus systemic heparin for CVST over the heparin treatment alone has not been proved. A retrospective study was conducted to analyze consecutive patients with CVST from 2005 to 2015. Patients having clinical improvement or stable disease after heparin treatment were in I/S group; patients having continuous deterioration of consciousness/neurological functions and refractory seizures (despite the use of multiple anti-epileptic drugs) after heparin treatment were in D group. EMT and OCT were indicated for patients in D group. Imaging studies and medical records were reviewed for statistical analysis. Safety issues included new-onset/progression of symptomatic intracerebral hemorrhages (ICH) or procedure-related complications. Total thirty patients were included (I/S group = 16; D group = 14). In D group, the mean time frame from the start of heparin treatment to the endovascular treatment was 3.2 days. Compared with I/S group, all patients in D group had complete stenosis of the sinuses, with higher initial mRS, lower initial GCS, and more seizures (p = 0.006, 0.007, and 0.031, respectively), but no significant differences in the mRS at discharge (p = 0.504). Shorter length of thrombosis and lower initial mRS were associated with better outcomes (p = 0.009 and 0.003, respectively). Thrombosis involving the superior sagittal sinus (SSS) was associated with bad outcomes (p = 0.026). There were two patients (6.7%) with worsening symptomatic ICH, one in each group, managed surgically. The overall mortality of the study was 6.7% (2/30). Combined EMT and OCT after heparin treatment for severe CVST were reasonably safe, which might be considered as a salvage treatment in severe CVST patients who are unresponsive to heparin with heavy clot burden involving SSS in the acute phase. However, further studies are needed to confirm its efficacy and validity.
Intact corticostriatal control of goal-directed action in Alcohol Use Disorder: a Pavlovian-to-instrumental transfer and outcome-devaluation study
Authors: van Timmeren Tim , Quail Stephanie L. , Balleine Bernard W. , Geurts Dirk E. M. , Goudriaan Anna E. , van Holst Ruth J. 
Published: March 2020

AbstractDeficits in instrumental, goal-directed control, combined with the influence of drug-associated Pavlovian-conditioned stimuli, are thought to influence the development and maintenance of addiction. However, direct evidence has mainly come from animal studies. We sought to establish whether alcohol use disorder (AUD) is characterized by behavioral or neurobiological deficits in (i) the integration of Pavlovian and instrumental values and (ii) goal-directed control; and (iii) whether duration or severity of AUD is associated with such deficits. The influence of cues predicting food rewards on instrumental action was assessed in a Pavlovian-to-instrumental transfer (PIT) test, measuring both specific and general PIT, and goal-directed behavior in an outcome-devaluation test. Brain activity was measured using functional MRI in 38 abstinent individuals with AUD and 22 matched healthy control individuals (HCs). We found significant specific and general PIT and outcome-devaluation effects across groups indicating goal-directed control, mediated by distinct corticostriatal signals, but no significant differences between individuals with AUD and healthy controls. Bayesian analyses provided substantial-to-strong evidence for the absence of group differences for these effects, or any relationship with duration or severity of AUD. These results suggest intact ability to integrate action-outcome associations on specific and general PIT and goal-directed learning in AUD during abstinence.
Photocatalytic Degradation of Organic Pollutants over MFe2O4 (M = Co, Ni, Cu, Zn) Nanoparticles at Neutral pH
Authors: Gupta Nishesh Kumar , Ghaffari Yasaman , Kim Suho , Bae Jiyeol , Kim Kwang Soo , Saifuddin Md 
Published: March 2020

AbstractIn this study, we report a surfactant-mediated synthesis of ferrites (MFe2O4: M = Co, Ni, Cu, Zn) using the co-precipitation-oxidation method. The band gap calculated from UV-Visible diffuse reflectance spectra were found in the range of 1.11–1.81 eV. These ferrite nanocatalysts were studied for the photocatalytic degradation of multiple organic dyes in a 32 W UV-C/H2O2 system. All the four ferrites showed an excellent dye degradation rate in the range of 2.065–2.417 min−1 at neutral pH. In the optimized condition, NiF was found to degrade 89%, 92%, 93%, and 78% of methylene blue, methyl orange, bromo green, and methyl red, respectively within 1 min of UV-irradiation. A 40% TOC removal was recorded after 5 min of degradation reaction, which increased to 60% after 50 min. Mechanism elucidated by scavenger studies and fluorescence spectroscopy revealed that •OH and holes were the primary reactive radicals responsible for the degradation process. Ferrite photocatalysts showed an insignificant performance loss in seven consecutive cycles. The photocatalyst was found efficient in the presence of a high concentration of salts. Thus, it was concluded that these photocatalysts are highly suitable for the remediation of dye-contaminated wastewater.
Proteogenomic analysis of granulocyte macrophage colony- stimulating factor autoantibodies in the blood of a patient with autoimmune pulmonary alveolar proteinosis
Authors: Hashimoto Atsushi , Takeuchi Shiho , Kajita Ryo , Yamagata Akira , Kakui Ryota , Tanaka Takahiro , Nakata Koh 
Published: March 2020

AbstractRecently, attempts to reveal the structures of autoantibodies comprehensively using improved proteogenomics technology, have become popular. This technology identifies peptides in highly purified antibodies by using an Orbitrap device to compare spectra from liquid chromatography–tandem mass spectrometry against a cDNA database obtained through next-generation sequencing. In this study, we first analyzed granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibodies in a patient with autoimmune pulmonary alveolar proteinosis, using the trapped ion mobility spectrometry coupled with quadrupole time-of-flight (TIMS-TOF) instrument. The TIMS-TOF instrument identified peptides that partially matched sequences in up to 156 out of 162 cDNA clones. Complementarity-determining region 3 (CDR3) was fully and partially detected in nine and 132 clones, respectively. Moreover, we confirmed one unique framework region 4 (FR4) and at least three unique across CDR3 to FR4 peptides via de novo peptide sequencing. This new technology may thus permit the comprehensive identification of autoantibody structure.
Mechanisms of allergen-specific immunotherapy for allergic rhinitis and food allergies
Authors: Lam Hiu Yan , Tergaonkar Vinay , Ahn Kwang Seok 
Published: March 2020

AbstractAllergen-specific immunotherapy (AIT) is currently the only potential treatment for allergies including allergic rhinitis (AR) and food allergies (FA) that can modify the underlying course of the diseases. Although AIT has been performed for over a century, the precise and detailed mechanism for AIT is still unclear. Previous clinical trials have reported that successful AIT induces the reinstatement of tolerance against the specific allergen. In this review, we aim to provide an updated summary of the knowledge on the underlying mechanisms of IgE-mediated AR and FA as well as the immunological changes observed after AIT and discuss on how better understanding of these can lead to possible identification of biomarkers and novel strategies for AIT.
Readability Following Cultural and Linguistic Adaptations of an Internet-Based Intervention for Tinnitus for Use in the United States
Authors: Beukes Eldré W. , Fagelson Marc , Aronson Elizabeth Parks , Munoz Maria F. , Andersson Gerhard , Manchaiah Vinaya 
Published: March 2020

PurposeAn Internet-based tinnitus intervention for use in the United States could improve the provision of tinnitus-related services. Although clinical trials of such interventions were completed in Europe, the United Kingdom, and Australia, their suitability for adults with tinnitus in the United States is yet to be established. The aim of this study was to improve the cultural and linguistic suitability, and lower the readability level, of an existing program for tinnitus to ensure its suitability for U.S. English- and Spanish-speaking populations.MethodGuidelines for adaptation were followed and involved four phases: (a) cultural adaptations, as interventions targeted at specific cultures have been shown to improve outcomes; (b) creating Spanish materials to improve access of the materials to the large Spanish-speaking population in the United States; (c) professional review of the materials for acceptability as an intervention tool for a U.S. population; and (d) literacy-level adjustments to make the content accessible to those with lower levels of health literacy skills.ResultsCultural adaptations were made by using word substitutions, changing examples, and modifying the spelling of certain words. The materials were then translated into Spanish and cross-checked. Professional review ensured suitability of the chapters. Literacy-level adjustments ensured all chapters were within the guidelines for readability grade levels below the sixth-grade level.ConclusionsThe previously developed tinnitus materials were revised to adhere to best practice guidelines and ensure cultural suitability for adults with tinnitus in the United States. As it is also available in Spanish, members of the large Hispanic community also have access to the intervention in their first language. Further studies should determine whether these changes improve patients' self-efficacy, engagement, and motivation to complete the intervention.
Dysphagia Management in Schools: A Survey of Speech-Language Pathologists
Authors: Felicetti Catherine , Richardson Kelly , Mansolillo Angela 
Published: March 2020

Purpose
To date, few studies have examined school-based pediatric feeding and swallowing practices across the United States. This study aims to (a) identify barriers to feeding and swallowing service provision in an educational setting and (b) identify the types of service suggested by school-based speech-language pathologists in response to a fictional case study.

Method
School-based speech-language pathologists and clinical fellows were invited to participate in a 15-min web-based survey. The survey questions addressed demographic and vocational information and perceived barriers to service provision. Survey respondents were also asked to develop a treatment plan in response to a fictional case study. In total, 200 anonymous survey responses were coded and analyzed using qualitative analysis methods.

Results
A number of barriers to practice were identified, which include academic and/or clinical preparedness and concerns related to the educational relevance of service. Analysis of the case study results indicated a wide range of treatment plans. The most common type of direct intervention suggested was an oral motor exercise regime, followed by diet modifications, and the implementation of safe swallow strategies.

Conclusions
Information gained in this study may be used to support policies and protocols related to the assessment and treatment of pediatric feeding and swallowing impairment in school settings.
Seven‐level boosting active neutral point clamped inverter using cross‐connected switched capacitor cells
Authors: Jagabar Sathik M. , Sandeep N. , Almakhles Dhafer , Bhatnagar Kaustubh , Yang Yongheng , Blaabjerg Frede 
Published: March 2020

In this study, an active neutral point clamped‐type boosting switched‐capacitor multilevel inverter (SCMLI) with self‐voltage balancing capability is proposed. In the proposed topology, a novel switched capacitor cell is used, which has eight switches and two diodes. The presented topology has reduced power component count with self‐boosting and balancing abilities. The distinctive features of the proposed topology are highlighted and benchmarked against other recent 7L‐SCMLI topologies. To validate the feasibility of the proposed topology, experimental tests are performed on a 1 kW prototype hardware setup.
Fluorescence enhanced detection of water in organic solvents by one‐pot synthesis of orange‐red emissive polymer carbon dots based on 1,8‐naphthalenediol
Authors: Yang Meiling , Liu Mingwang , Wu Zipeng , He Yu , Ge Yili , Song Gongwu , Zhou Jiangang 
Published: March 2020

A facile method for fabricating polymer carbon dots (PCDs) with characteristic dual‐emission at 570 and 620 nm by 1,8‐naphthalenediol in n‐propanol solvents was designed. The synthesised PCDs possessed fluorescence enhancement performance toward the water in organic solvents. Based on this peculiar phenomenon, a highly efficient fluorescent probe for water detection in organic solvents such as N,N‐dimethylformamide, dimethyl sulfoxide and n‐propanol was established with a wide detection range from 0 to 50%. The probe can also be utilised to determine water content in other organic solvents. The practical application was explored by studying the response of PCDs toward the water in various spirit samples. This method may offer a new way of detecting water in organic solvents by PCDs.
Preparation of CuO@PPy hybrid nanomaterials as high cyclic stability anode of lithium‐ion battery
Authors: Feng Lili , Zhang Wei , Wang Rui , Xu Linan , Li Dongzhi , Xiao Congli , Zhang Yinyin 
Published: March 2020

Over the recent 20 years, numerous researches have focused on the lithium‐ion batteries anodes of MOx 3d‐metal oxides which have a high specific capacity. For example, the specific capacity of CuO material as an anode is ∼670 mAh g−1. Unfortunately, serious capacity degradation limits their promising applicability. To improve cyclic stability, PPy is covered on CuO surface to prepare CuO@PPy core–shell hybrid materials by chemical polymerisation. Pyrrole amount plays an important role on control the PPy shell thickness. After PPy coating, the lithium‐ion battery cycling stability and coulombic efficiency have been improved greatly, and CP‐5 sample has the best cyclic stability and coulombic efficiency. The capacity retention of bare CuO is only 27.9% after 200 cycles. By contrast, the capacity retention of CP‐5 sample is ∼100%. The flexible conducting polymers shell (PPy) lead to improved cyclic stability. These results give a strategy to solve MOx 3d‐metal oxide capacity degradation as Lithium‐ion batteries anode.
The VMC Survey
Authors: Groenewegen M. A. T. , Nanni A. , Cioni M.-R. L. , Girardi L. , de Grijs R. , Ivanov V. D. , Marconi M. , Moretti M.-I. , Oliveira J. M. , Petr-Gotzens M. G. , Ripepi V. , van Loon J. Th. 
Published: March 2020

Context. Variability is a key property of stars on the asymptotic giant branch (AGB). Their pulsation period is related to the luminosity and mass-loss rate of the star. Long-period variables (LPVs) and Mira variables are the most prominent of all types of variability of evolved stars. The reddest, most obscured AGB stars are too faint in the optical and have eluded large variability surveys.
Aims. We obtained a sample of LPVs by analysing K-band light curves (LCs) of a large number of sources in the direction of the Magellanic Clouds with the colours expected for red AGB stars ((J − K) > 3 mag or equivalent in other colour combinations).
Methods. Selection criteria were derived based on colour-colour and colour-magnitude diagrams from the combination of the VISTA Magellanic Cloud (VMC) survey, Spitzer IRAC and AllWISE data. After eliminating LPVs with known periods shorter than 450 days, a sample of 1299 candidate obscured AGB stars was selected. K-band LCs were constructed by combining the epoch photometry available in the VMC survey with literature data, were analysed for variability, and fitted with a single period sine curve to derive mean magnitudes, amplitudes, and periods. A subset of 254 stars are either new variables, known variables where the period we find is better determined than the literature value, or variables with periods longer than 1000 days. The spectral energy distributions (SEDs) of these stars were fitted to a large number of templates. For this purpose the SEDs and Spitzer IRS spectra of some non-AGB stars (Be stars, HII regions and young stellar objects – YSOs) were also fitted to have templates of the most likely contaminants in the sample.
Results. A sample of 217 likely LPVs is found. Thirty-four stars have periods longer than 1000 days, although some of them have alternative shorter periods. The longest period of a known Mira in the Magellanic Clouds from Optical Gravitational Lensing Experiment data (with P = 1810 d) is derived to have a period of 2075 d based on its infrared LC. Two stars are found to have longer periods, but both have lower luminosities and smaller pulsation amplitudes than expected for Miras. Mass-loss rates and luminosities are estimated from the template fitting. Period-luminosity relations are presented for carbon (C-) and oxygen (O-) rich Miras that appear to be extensions of relations derived in the literature for shorter periods. The fit for the C stars is particularly well defined (with 182 objects) and reads Mbol = (−2.27 ± 0.20) ⋅ log P + (1.45 ± 0.54) mag with an rms of 0.41 mag. Thirty-four stars show pulsation properties typical of Miras while the SEDs indicate that they are not. Overall, the results of the LC fitting are presented for over 200 stars that are associated with YSOs.
Mitigating flicker noise in high-precision photometry
Authors: Sulis S. , Lendl M. , Hofmeister S. , Veronig A. , Fossati L. , Cubillos P. , Van Grootel V. 
Published: March 2020

Context. In photometry, the short-timescale stellar variability (“flicker”), such as that caused by granulation and solar-like oscillations, can reach amplitudes comparable to the transit depth of Earth-sized planets and is correlated over the typical transit timescales. It can introduce systematic errors on the inferred planetary parameters when a small number of transits are observed.
Aims. The objective of this paper is to characterize the statistical properties of the flicker noise and quantify its impact on the inferred transit parameters.
Methods. We used the extensive solar observations obtained with SoHO/VIRGO to characterize flicker noise. We simulated realistic transits across the solar disk using SDO/HMI data and used these to obtain transit light curves, which we used to estimate the errors made on the transit parameters due to the presence of real solar noise. We make these light curves publicly available. To extend the study to a wider parameter range, we derived the properties of flicker noise using Kepler observations and studied their dependence on stellar parameters. Finally, we predicted the limiting stellar apparent magnitude for which the properties of the flicker noise can be extracted using high-precision CHEOPS and PLATO observations.
Results. Stellar granulation is a stochastic colored noise, and is stationary with respect to the stellar magnetic cycle. Both the flicker correlation timescales and amplitudes increase with the stellar mass and radius. If these correlations are not taken into account when fitting for the parameters of transiting exoplanets, this can bias the inferred parameters. In particular, we find errors of up to 10% on the ratio between the planetary and stellar radius (Rp∕Rs) for an Earth-sized planet orbiting a Sun-like star.
Conclusions. Flicker will significantly affect the inferred parameters of transits observed at high precision with CHEOPS and PLATO for F and G stars. Dedicated modeling strategies need to be developed to accurately characterize both the star and the transiting exoplanets.
Atypische diabetische Ketoazidose bei Patienten mit Typ-2-Diabetes unter SGLT-2-Therapie
Authors: Kopf Stefan 
Published: March 2020

ZUSAMMENFASSUNGDie Therapie mit SGLT-2-Inhibitoren bei Patienten mit Diabetes mellitus nimmt aufgrund der positiven Ergebnisse auf kardiovaskuläre Ereignisse zu. Dadurch kommt es auch zu einer Zunahme der unerwünschten Nebenwirkungen. Eine seltene, aber lebensbedrohliche Nebenwirkung ist die atypische oder euglykämische diabetische Ketoazidose. Diese Nebenwirkung wird in allen Präparaten dieser Substanzklasse beschrieben. Statistisch ist es eine seltene Nebenwirkung mit einer Inzidenzrate von 0,1–2,2 %. Typische Symptome sind unter anderem Übelkeit, Bauchschmerzen, Erbrechen, vermehrter Durst und Verwirrtheitszustände. Als auslösende Faktoren werden reduzierte Nahrungsaufnahme, Infektionen, reduzierte Insulindosis und größere chirurgische Eingriffe angesehen. Bei Verdacht auf eine solche atypische diabetische Ketoazidose muss sofort ärztliche Hilfe in Anspruch genommen werden.