bluuebunny/crossref_metadata_2025_split huggingface dataset:
جهود المعلم في ترقية الإنجاز التعلم للتلاميذ بمعهد مرضات الله
Authors: Lubis Ali Asrun , Siagian Sri Rezeki 
Published: October 2020

AbsrakMasalah dalam penelitian ini adalah apa bentuk upaya guru dalam meningkatkan prestasi belajar siswa dalam pembelajaran nahwu di pondok pesanteren mardatillah, dan problem apa yang dihadapi guru dalam meningkatkan prestasi belajar siswa dalam pembelajaran nahwu di pondok pesanteren mardatillah. Metode penelitian yang peneliti gunakan akan adalah penelitian kualitatif deskriptif dengan cara menggambarkan fenomena-fenomena dan fakta-fakta dengan cara mengumpulkan data-data melalui observasi dan wawancara. Hasil penelitian ini guru menyempurnakan upayanya dalam pembelajaran nahwu dengan menggunkan metode yang layak, dan menentukan tujuan pembelajaran pembelajaran dengan tujuan pribadi, memberikan rangsangan pada siswa, memeberikan hadian pada siswa, lalu factor-faktor yang dihadapi guru ada dua factor internal seperti perbedaan kemampuan dan perhatian dan motivasi siswa dan factor eksternal metode cenderung monoton pada metode ceramah, Tanya jawab dan media pembelajaran dan kekurangan biaya.
استخدام وسائل الصورة في تحسين مهارة كتابة اللغة العربية في مدرسة الثانوية الإسلامية
Authors: Sihotang Nurfin , Ningsih Surya 
Published: October 2020

AbstrakMasalah dalam penelitian adalah penggunaan media gambar dalam memperbaiki kemahiran menulis bahasa arab siswa, media yang digunakan adalam media gambar, tujuan penelitian ini adalah ada atau tidak adanya pengaruh penggunaan media bergambar terhadap kemahiran menulis bahasa arab siswa kelas tujuh madrasah darul istiqomah Huta Padangsidimpuan, metode penelitian ini adalah metode penelitian tindakan kelas dengan menggunakan penggunaan media bergambar terhadap kemahiran menulis bahasa arab siswa kelas tujuh madrasah darul istiqomah Huta Padangsidimpuan. Hasil penelitian ini menunjukkan adanya pengaruh media gambar terhadap kemahiran kemahiran menulis bahasa arab siswa, media gambar sangat berguna dalam memperbaiki kemahiran menulis bahasa arab siswa. Berdasarkan hasil ini makan dapat diterima hipotesis penetian dengan hasil 63 % hasil siklus I dan 65 % hasil sikus II dan 80 siklus III.
الدافع في تعلم اللغة العربية
Authors: Siregar Rahma Hayati , Nasution Ja'far 
Published: October 2020

الاجتهاد شروط وأحد الإسلام جوهرة جزء موقعها لأن للغاية مهمة لغة العربية اللغة تعتبر لا يمكن فهم الإسلام المأخوذ من مصادره وأخذ قانون الاستنبتة إلا باللغة العربية. واقع المسلمين اليوم بشكل عام، وكثير منهم يتجاهل اللغة العربية لذا من المهم جدًا تحفيز الطلاب على تعلم اللغة العربية إن توليد الدافع لتعلم اللغة العربية في المدرسة ليس سهلاً، يجب على المعلمين وأولياء الأمور أن يلعبوا دورًا لزيادة الدافع لتعلم اللغة العربية. يحافظ المعلمون العرب المحترفون على تحفيز الطلاب على تعلم اللغة العربية. تؤثر طريقة التعلم بشكل كبير على تحفيز الطلاب لتعلم اللغة العربية لأن مفتاح عملية التعلم هو الطريقة التي يستخدمها المعلم وبالمثل، فإن دور وسائل الإعلام في عملية تعلم اللغة العربية مهم بالطبع، بالإضافة إلى تحقيق هدف التعلم يمكن أن يثير أيضًا تحفيز الطلاب على تعلم اللغة العربية.. دور أولياء الأمور في إعطاء المزيد من الاهتمام والحماس للتعلم حتى يتمكن من إثارة الدافع لتعلم الطلاب العرب لأن الوقت في المنزل أكثر من الوقت في المدرسة.
Degradable Evaluation of Two Types of Biopolymers in Loam Soil
Authors: Hussain Leqaa M. , Hassan Salma M. , Bahia M. Hassan S. 
Published: October 2020

Gel-biopolymers were prepared by different weights of two polymers (PVA, and PEG) dissolved with distilled water. Thick films of these polymers were prepared by using the casting method, with different thicknesses (t= 0.48, 0.34mm for PVA and t=0.58 mm for PEG). The objective of this research is to determine the viability of the organic polymer films of PEG and PVA on decomposition and the time required for their degradation in the soil. The purpose is to use these polymers in industry without leaving plastic residues along with the possibility of their application as fertilizers for soil. The results showed that PEG film was degraded during the first week, while PVA film was changed in weight from 0.3 to 0.23 g and thickness from 0.34to 0.21 cm. We also observed change in the shape of the sample along with ripples and holes during three month.
Studi Teknis Dan Ekonomis Dimensi Konstruksi Kapal Kayu Berdasarkan BKI
Authors: Aditya Bagus Kusuma , Supomo Heri , Ma'ruf Buana 
Published: October 2020

Wooden ships are one of the non-steel ships that are widely available in Indonesian waters, which are built using conventional methods. In this study, a survey was conducted to determine the dimensions of the construction elements on the ship's kasko from the keel to the main deck, the price of wood materials and the construction process using interview and observation methods. Existing ship data is analyzed according to the 1996 BKI Rule on wooden ships to determine the level of comparison for each element of ship construction. Existing ship construction data based on regulatory analysis is modeled to get the optimum reductions of construction dimensions. Based on the results of the technical and economic analysis of the three vessels, it is known that the two existing ships have heavier construction than the calculation according to the BKI Rules. This is influenced by differences in ivory spacing, deck beam distance, outer shell thickness and deck thickness. The size of the construction dimensions is proportional to its economic value. Therefore, to determine the optimum level of reduction in construction dimensions, structural modeling is used. In the modeling that is done, it is found that the value of the reduction in construction dimensions is 10%, 20% and 30%. This reduction was carried out because the magnitude of the stress of the three ships according to the BKI Rules was still far below the limit allowed according to BKI 12,75 N/mm2. According to the results, the recommendation for the reduction in construction dimensions is up to 20%. The 30% reductions were not recommended because the stress value is over than the stress limit. The allowable stress is 12,75 N/mm2. Based on the data, it can be conclude that the economic value also can be reduced up to 20%.
Ideologi Kapitalisme dalam Kepopuleran Sang Pemimpi
Authors: Manik Ricky A. 
Published: October 2020

Novel Sang Pemimpi (SP) in various views seem to encourage people not to give up and become desperate in achieving their dreams. It is believed that to be a successful person requires hard work and strong discipline. The credence of this perspective named as the capitalism ideology. This is what makes this novel becomes popular. The problems are what kind of the capitalism ideology appears in the view of the characters and why SP is positioned as a popular literature. This research aims to find the capitalism ideology in SP and its popularity position. The method and theory were used with two steps. First, the position of SP was put as a popular novel by referring to popular literature characters. Second, the capitalism ideology concept and theory were used to know the capitalism ideology of the characters. This research found that SP is a popular literature. The capitalism ideology in SP is to be a hard-working person with strong discipline which is certainly beneficial for the capital owners. AbstrakNovel Sang Pemimpi (SP) dalam berbagai pandangan seolah mengajak orang untuk tidak menyerah dan putus asa dalam mencapai cita-cita. Dengan kerja keras dan disiplin yang tinggi, seseorang diyakini akan berhasil. Keyakinan akan pandangan ini disebut sebagai ideologinya kapitalisme. Itu pula yang membuat novel ini begitu populer. Permasalahannya adalah ideologi kapitalisme apa yang muncul dalam pandangan para tokoh dan mengapa SP diposisikan sebagai sastra populer. Tujuan dari penyelisikan ini adalah menemukan ideologi kapitalisme dalam SP dan posisi kepopulerannya. Metode dan teori yang digunakan adalah dengan dua langkah. Pertama, mendudukkan posisi novel SP sebagai novel populer dengan mengacu pada ciri-ciri sastra populer. Kedua menggunakan konsep dan teori ideologi kapitalisme dalam melihat ideologi kapitalisme tokoh-tokoh. Hasil penelitian ini menemukan bahwa novel SP merupakan sastra populer. Adapun ideologi kapitalisme yang terdapat dalam SP adalah menjadi manusia yang pekerja keras dan memiliki disiplin yang tinggi yang tentu saja dapat menguntungkan kaum pemilik modal.
GLYCOLYTIC 2-DEOXY-D-GLUCOSE PERIOCULAR INHIBITOR SEBAGAI TERAPI ADJUVANT PADA RETINOBLASTOMA
Authors: Azlia Demara, Yedhi , Kusumastuti Laily Annisa , Wicaksana Daffa Abhista 
Published: October 2020

Retinoblastoma is the most common intraocular tumor in children. Retinoblastoma tumors consist of areas with high angiogenic activity and other areas with low oxygen pressure conditions. Tumor cells that survive in this hypoxic region have been shown to be resistant to chemotherapy and radiation, namely standard retinoblastoma therapy which selectively targets rapidly dividing cell populations, so that therapy is needed that can reach up to the hypoxic cells. 2-deoxy-D-glucose (2-DG) has been shown to be effective in reducing hypoxic areas in tumors, reducing tumor buds, and inhibiting angiogenesis. to discuss the glycolytic 2-DG inhibitors as adjuvant therapy in retinoblastoma. The authors searched for medical articles in the PubMed and ResearchGate literature databases with the keywords treatment, 2-deoxy-D-glucose, 2-DG, retinoblastoma, and cancer. The words are combined with OR or AND using Boolean logic. Based on the selection according to the inclusion and exclusion criteria, 4 articles were used as the main reference for writing this review literature. 2-DG will disregulate (inhibit) the process of angiogenesis through upregulation of Estrogen Receptor 1 Nuclear (ESR 1), ubiquitin, jun activation domain binding protein 1 (JAB1), G-protein alpha S, and CAPER in the apical part of the tumor and B3GNT1 upregulation , CEPT1, PABPC1, myotrophin, HAX1 in the postero-lateral part of the tumor. H3, DTX1, RPL12, and bone morphogenic (BMP) histones are also upregulated so that hypoxia can be inhibited. With this mechanism, the tumor burden can be suppressed. Glycolytic 2-DG inhibitors with anti-angiogenesis and anti-hypoxic abilities can be developed as adjuvant therapy for advanced retinoblastoma patients.
POTENSIAL MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES (MSC-EVS) SEBAGAI TERAPI TERBARU DALAM OBAT ISKEMIK RETINAL
Authors: Sisca Sisca , Azizah Nurul , Al Aldi M.Salas 
Published: October 2020

Retinal ischemia (IR) is still the biggest cause of blindness in the world. Several factors contribute to the pathogenesis of Retinal Ischemia. However, oxidative stress and inflammatory processes are the main factors. Various forms of therapy have been applied in clinical care of Retinal ischemia, but none have been optimal for repairing the cells damage and able to avoid immunological and oncogenic reactions. MSC-EVs have opened a new perspective for the treatment of Retinal Ischemia. MSC is a multipotent cell with paracrine characteristic and mediated by extracellular vesicles (EVs) which is derivative of MSC that can be used as a biomimetic agent to help nerve protection and tissue regeneration. In addition, MSC-EVs have a lower tendency to trigger immune responses and the inability to directly form tumors. Therefore, MSC EVs can prove to be an ideal source for the latest therapies in dealing with the problem of retinal ischemia. This Literature Riview is compiled by using a literature study with collecting valid journals, particular inclusion and exclusion criteria. On testing its effectiveness, three indicators were used, that is the protective effect of MSC-EVs on retinal cells, the effects of post-ischemic in vivo administration of MSC-EVs, and the distribution of MSC-EVs in humour vitreous and long-term protective effects estimates. Significantly shows a protective effect, decreases inflammatory factors and apoptosis of retinal cells. Based on the results of testing in vitro and in vivo MSC-EVs are endocytosis by retinal cells that provide neuroprotective effects before and after treatment, and this effect can be developed into long-term therapy. Therefore, using MSC-EVs can be a promising therapy in the treatment of retinal ischemia.
REGENERASI DENDRIT SEL GANGLION RETINA: PERAN INSULIN UNTUK MENGEMBALIKAN PENGLIHATAN PADA GLAUKOMA
Authors: Azizah Nurul , Sisca Sisca , Rasiha Rasiha 
Published: October 2020

Glaukoma is a leading cause of irreversible blindness worldwide. This disease is associated with characteristic damage to the optic nerve and permanent retinal ganglion cell (RGC) degeneration. A crucial step towards circuit repair in glaucoma is to promote damaged RGCs to regenerate not only axons, but also dendrites to successfully reconnect with their synaptic partners. The latest research showed that insulin signalling has the capacity to regenerate dendrites dan injured synapses, therefore the use of insulin raises a new paradigm as a new pro-regenerative therapeutic target for the disease of glaucoma. This literature review is made using literature searching of valid journals with inclusion and exclusion criteria. On the experiment of insulin’s effectivity, it is valued using 4 indicators; promote dendrite regeneration, restore synaptic density, rescue retinal function, robust neuronal survival. Based on in vivo experiment, insulin endowed with the ability to effectively restore dendritic morphology thus enhancing the function and survival of RGC through mTORC1 (mammalian target of rapamycin complex 1) and mTORC2 (mammalian target of rapamycin complex 2) signalling, this supports that that it can be promising therapeutic targets to counter progressive RGC neurodegeneration and vision loss in glaucoma.
HUBUNGAN MOTIVASI INTRINSIK TERHADAP PELAKSANAAN PEMBELAJARAN LANGSUNG DI FAKULTAS KEDOKTERAN HALU OLEO UNIVERSITAS KENDARI
Authors: Ashaeryanto Ashaeryanto , Wicaksono Satrio , Saimin Juminten , Fitrianti Rezki 
Published: October 2020

Self-Directed Learning (SDL) is a student-centered learning in which the process and experience of learning are individually regulated and controlled by the student. The implementation of SDL is an interaction of several aspects, including self-motivation, self-control, and self-monitoring skills. Students with strong motivation in the learning process will have more consistency in implementing the SDL. Inner self-motivation will give better impacts than that obtained from the outside. This study aimed to analyze the correlation of intrinsic motivation to SDL implementation in the Faculty of Medicine of Halu Oleo University. The study was quantitative research using a cross-sectional design. Subjects were 91 sophomores of the Faculty of Medicine of Halu Oleo University (UHO). Data were collected using a total sampling method. SDL implementation and intrinsic motivation were measured using Self-Directed Learning Readiness Scale (SDLRS) and Intrinsic Motivation Inventory (IMI) questionnaires, respectively. Data were statistically analyzed using Pearson’s correlation. Second-year of medical students of UHO showed a high intrinsic motivation and SDL implementation. Students with high intrinsic motivation were found to apply high implementation of SDL. Moreover, students with moderate intrinsic motivation also showed high implementation of SDL. There is a significant correlation between intrinsic motivation to SDL implementation among medical students of UHO. Further research is required to investigate other factors that affect the SDL implementation of medical students.
POTENSI SEL T MOBIL HER2 SPESIFIK MODIFIKASI CRISPR / CAS9 PD-1 / PD-L1 PEMBLOKIRAN SEBAGAI INOVASI TERAPI UVEAL MELANOMA
Authors: Khoiruddin Muhammad AH , Febriyanti Yusi Windya , Amalia Nafia 
Published: October 2020

Uveal Melanoma (UM) is the primary intraocular tumor most commonly found in adults. The combination of therapy, Brachytherapy, surgery, Tranpupillary Thermal Therapy (TTT), Proton Beam Theraphy has not produced satisfactory results. The discovery of HER2 receptors expressed by UM cells can be used as a specific antigen target for the treatment of CAR T-celss. However, the effectiveness of CAR T-cell immunotherapy in tumors results in immunosuppressive T cells caused by an increase in Programmed cell Death Ligand-1 (PD-L1). This literature review demonstrates the success of HER2-specific CART T Cells as UM therapeutic efforts capable of eliminating tumor cells. In addition, CRSPR / Cas9 PD-1 / PD-L1-blocking modified HER2-specific CAR T cells can be a gene innovation in UM sufferers. Further clinical trials are needed to prove the effectiveness of CRISPR / Cas9 PD-1 / PD-L1-Blocking modified HER2-specific CAR T Cells in the treatment of UM patients.Keywords: Uveal melanoma, CAR T cell, reseptor HER
POTENSI ASAM FATTY OMEGA 3 DALAM PERLINDUNGAN RETINAL MELALUI GPR120 / ARRESTIN2 TANDA TANDA AKTIVASI PATHWAY SEBAGAI SEBUAH PREVENTIF INOVATIF DAN TERAPI KATATIF TERAPI DIABETIK RETINOPATI DIABETIK
Authors: Dwi Latifa Kurnia , D.Sanjiwani Made Indira , Widya Mulyani W. Riski 
Published: October 2020

Diabetes mellitus especially type 2 diabetes mellitus is a chronic metabolic disease with a high prevalence and risk of complications. Diabetic retinopathy is a common complication. Current diabetic retinopathy therapy tends to be expensive and often leads to recurrence. Therefore more effective therapies are needed with abundant resources so that they are affordable for the community. Based on research, omega 3 fatty acids can be used as preventive and curative therapy for diabetic retinopathy. This modality is proven to be effective in preventing worsening of diabetic retinopathy and even reducing the signs of vascular abnormalities which are the main problem in this disease. Recent studies have also found signaling pathways involving GPR120 in the pathogenesis of diabetic retinopathy. Even GPR120 which is a receptor for omega 3 fatty acids has the potential as an effective therapeutic target in the prevention of worsening and treatment of diabetic retinopathy. Keywords: GPR120, Omega 3 fatty acids, diabetic retinopathy
HUBUNGAN ANTARA TINGKAT KREATIVITAS VERBAL DENGAN KEMAMPUAN BERBAHASA INGGRIS PADA MAHASISWA JURUSAN PSIKOLOGI ISLAM IAIN PONTIANAK ANGKATAN 2017/2018
Authors: Mardiati Isyatul Mardiati 
Published: October 2020

Abstract This study described about: (1) the level of verbal creativity of students of the Islamic Psychology Ushuluddin, Adab and Da’wah Faculty, Islamic State Institute of Pontianak 2017/2018; (2) English language proficiency of students of the Islamic Psychology Ushuluddin, Adab and Da’wah Faculty, Islamic State Institute of Pontianak 2017/2018; (3) the relationship between the level of verbal creativity and English language proficiency of students of the Islamic Psychology Ushuluddin, Adab and Da’wah Faculty, Islamic State Institute of Pontianak 2017/2018. The sample in this study were students of the Department of Islamic Psychology, Faculty of Ushuluddin, Adab and Da'wah, Islamic State Institute of Pontianak. The results of this study are that there is a positive correlation between verbal creativity with English language proficiency in Islamic Psychology students From this research, it can also be seen that the level of verbal creativity of Islamic Psychology students is quite high with a percentage of 49.2% and English proficiency of students has a high category in reading skills. Keywords: Verbal Creativity, English Proficiency
INTRODUCING CRYSTALLIZATION BACKWARD SUCTION TRAPPING LIPIDS AND DEBRIS AS PROPOSED ADDITIONAL FACTOR IN THE GENESIS OF CORONARY ARTERY DISEASE
Authors: Embi Abraham A. 
Published: October 2020

Coronary artery disease progression involves a slow process of abnormal accumulation of lipid deposits to the inner walls of the arteries followed by an immune system response. It is known that an increase in lipid concentration could trigger cholesterol crystals deposition, thus starting a vicious cycle that could also progress into intra-arterial plaque formation, the hallmark of mature atheromas.
The purpose of this manuscript is to introduce a proposed mechanism for the genesis of coronary artery disease; whereby the actual act of lipids crystallization starts a cycle demonstrated to induce additional crystallization via dehydration. Experiments demonstrate for the first time via images and video-recordings showing that when the onset crystallization occurs near the tissue (≅ 1 mm) a dehydration triggered backward hydrodynamic suction or vacuum ensues with enough force to withdraw lipid molecules from human tissue; these molecules are shown to adhere to the crystals.
EXPERIENTIAL LEARNING: AN ANALYSIS OF IMPACT ON ACADEMIC ACHIEVEMENT AMONG STUDENTS OF GRADE 12
Authors: Thote Prashant , S Gowri 
Published: October 2020

The molecular model as a learning tool in class-room instructions is significant due to its positive effect on the learning and teaching process. Many students struggle to learn Chemistry and do not succeed. Chemistry is the central part of all Science subjects. To make Chemistry learning easy and joyful appropriate method of class-room instructions are important. The Chemistry of solid states and composite materials is the part of the curriculum at All India Senior Secondary School Curriculum. Students face problems in solid state Chemistry due to its abstract concepts. To address the issue, handmade models and paper-based models are made as evidence-based learning. In this present paper attempt is made to investigate the impact of handmade paper model of unit cell and crystal lattices of solid-state Chemistry on academic achievement. The study is delimited to the students of only one school in rural area. Totally 50 students participate in the study. Sample is distributed into two groups: study group and the control group, by connecting them on the basis of the previous knowledge which is determined through pre-test. The students of the study group are taught solid states Chemistry through handmade paper models of unit cells and crystal lattices and the students of the control group are taught by using traditional chalk and board method. Data is collected by using Test (Pre and Post). Mean standard deviation and mean differences are used as a statistical tool to analyze the data. Substantial difference between the study group and the control group of mean score on test (pre and post and retention) are tested at 0.05 level. The handmade paper model of unit cell and crystal lattices of solid states Chemistry has significant positive impact on the academic achievement in solid state Chemistry. Based on the findings of the present study, some recommendations are made for using paper model as teaching aid for evidence-based learning in Chemistry and other core subjects to move up the students’ academic performance level.