bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on Evaluation and Prevention of Impact Risk of Hard and Thick Coal Seam
Authors: Wang ZHonghua 
Published: October 2020

Abstract
In order to prevent and control the rockburst of the hard and thick coal seam in 22 panels, the laboratory tested the impact propensity of coal seams and roof rock layers. It used the comprehensive index method and microseismic monitoring to evaluate the risk of medium rock burst 3# coal seam in 22 panels. Anti-scouring countermeasures are proposed, including regional anti-scouring, local anti-scouring, danger zone relief, anti-scouring effect inspection and safety protection, etc., which provide reference for mines with similar conditions.
Visual Analysis of Ming and Qing Style Furniture Research Based on CiteSpace
Authors: Qu Hongyue , Lyu Jianhua , Chen Ming 
Published: October 2020

Abstract
In order to understand the research hotspots of Ming and Qing style furniture in China in the past 20 years, and provide reference for the research direction of Ming and Qing style furniture. Based on the CiteSpace software, comparative analysis method and quantitative analysis method were used to visually analyze 539 journal papers in the field of Ming and Qing style furniture from 2000 to 2019 in the CNKI database. The results show that the relevant research literature from 2000 to 2012 found a significant growth trend, which began to decrease in 2013. At present, stable core author groups have been formed, but there is relatively little cooperation between various groups. Northeast Forestry University is the main research institution, but other inter-provincial institutions have less cooperative research. Hot research contents mainly focus on the shape, decoration and materials of Ming and Qing style furniture. Eight clusters formed by the keywords have good clustering effect, which can fully reflect the key research interests in this research field. To sum up the results, in the future, we should strengthen the communication and cooperation between the authors and between the institutions, and establish a systematic database for research on Ming and Qing style furniture. Through reasonable design techniques, the symbols of Ming and Qing furniture could be merged into modern design, new materials and instruments could be combined to further promote the inheritance of Ming and Qing style furniture.
Accident Analyses of Optimal Designed Primary Loop
Authors: Chen Lei , Song Feifei , Jia Zhen 
Published: October 2020

Abstract
Through optimizing the operational and the structural parameters, the weight, volume or the efficiency. etc of primary loop can be imporved. To study the transient behaviours of the optimal scheme under desigend based accidents, we use RELAP5 code to build simulaiton model of the primary loop, and set conservative boudary conditions and initial conditions to make simulations of loss of feed water accident and station blackout accident for both of the optimal scheme and the prototype. The study shows that the core safety can be guaranteed under the accidents.
Numerical Simulation of Reinforced Soil Slope in Subgrade Widening of Expressway
Authors: Gao Song-jie , Tang Bin , Zhang Jing , Zhao Gang 
Published: October 2020

Abstract
The finite difference element software FLAC3D was used to simulate the reconstruction and expansion project of Xinle-Yuanshi expressway. The model of reinforced soil slope widening subgrade was established. Based on the comparison of the simulation data of the sections with different heights and structural forms, the structural behavior of reinforced soil structure in subgrade widening project was analyzed. The law of structural deformation and construction control technology were summarized.
Field test study on reinforced soil steep slope in subgrade widening of Highways
Authors: Chen Lei , Liu Cui , Zhao Hui , Zhao Xin-li 
Published: October 2020

AbstractTo study the application effect of the reinforced soil steep slope structure in the subgrade widening project of highways under the condition of limited land occupation, based on the Xinyuan expressway reconstruction and expansion project, this paper conducts field test and research on the structural state of the reinforced soil structure, and selects a natural grading subgrade widening section to compare the widening effect. Through buried sensors to monitor the settlement of the cross-section of the foundation and analyze the change law of the data after the operation. Based on the research on the structural state of reinforced soil steep slope widening subgrade, this paper summarizes the structural deformation law, construction key technology and control method in the construction process and the initial operation stage.
Cytomorphologic Spectrum of SMARCB1-Deficient Soft Tissue Neoplasms
Authors: Schaefer Inga-Marie , Al-Ibraheemi Alyaa , Qian Xiaohua 
Published: October 2020

Abstract

Objectives
The SWI/SNF complex core subunit SMARCB1 is inactivated in a variety of neoplasms that share characteristic “rhabdoid” cytomorphology. The aim of this study was to evaluate SMARCB1-deficient soft tissue neoplasms on cytology to identify diagnostic clues.

Methods
Eleven SMARCB1-deficient tumors, including six epithelioid sarcomas, three malignant rhabdoid tumors, one epithelioid malignant peripheral nerve sheath tumor (MPNST), and one poorly differentiated chordoma with fine-needle aspiration (FNA), serous effusion, or touch prep (TP) from two institutions, were included. Targeted next-generation sequencing (NGS) was performed in two cases.

Results
Evaluation of FNA (n = 4), effusion (n = 4), and TP (n = 3) in nine adult and two pediatric patients demonstrated cellular samples (n = 11), epithelioid cells with rhabdoid morphology (n = 9), eccentrically located nuclei with prominent nucleoli (n = 7), and cytoplasmic bodies (n = 4); two patients were diagnosed on FNA with cell block. Immunohistochemistry (IHC) demonstrated SMARCB1 loss in all cases and keratin and/or EMA expression in all but the epithelioid MPNST; NGS identified SMARCB1 inactivation in both cases.

Conclusions
SMARCB1-deficient soft tissue neoplasms comprise a variety of tumors with epithelioid morphology and frequent expression of keratin and/or EMA. Recognition of characteristic rhabdoid morphology on cytology can prompt IHC and/or NGS testing for SMARCB1 deficiency and help establish the diagnosis.
Utility of Flow Cytometry and Fluorescence In Situ Hybridization in Follow-up Monitoring of Plasma Cell Myeloma
Authors: Chopra Saurav , Dunham Timothy , Syrbu Sergei I , Karandikar Nitin J , Darbro Benjamin W , Holman Carol J 
Published: October 2020

AbstractObjectivesWe sought to investigate the clinical utility of flow cytometry (FC) and fluorescence in situ hybridization (FISH) in the workup of myeloma.MethodsWe retrospectively reviewed the reports of bone marrow biopsies received for myeloma evaluation between October 2015 and January 2019.ResultsA total of 1,708 biopsy specimens from 469 myeloma patients (mean age, 64.5 years [SD, 9.3]; female, 41.4%) were reviewed. Both FC and FISH had comparable detection rates at the time of initial diagnosis (97.6% vs 98.8%) and for follow-up cases (28.6% vs 28.2%). FC and FISH results were concordant in 98.8% of the initial diagnosis cases and 89.6% of the follow-up cases. The FISH-positive (FISH+)/FC-negative (FC−) discordance and FISH−/FC+ discordance occurred among 81 (5.0%) and 87 (5.4%) follow-up cases. In comparison with all concordant cases, FISH+/FC− discordant cases were more likely to have received treatment with daratumumab (P &lt; .05).ConclusionsPlasma cell–enriched FISH and FC have comparable abnormal plasma cell detection rates, and approximately 10% of the follow-up cases have discordant FISH and FC results in which residual disease is detected by only one of these modalities. FISH testing should be considered for cases with negative FC, especially in patients who have received treatment with daratumumab or in cases in which there is concern about specimen adequacy.
A Tertiary Academic Medical Center Blood Bank’s Experience With Four-Factor Prothrombin Complex Concentrate
Authors: Shmookler Aaron D , Nichols Tracie L , Perrotta Peter L 
Published: October 2020

Abstract

Objectives
The role of transfusion medicine consultative services in prospectively auditing (PA) orders for four-factor prothrombin complex concentrate (4F-PCC) was evaluated at an academic medical center.

Methods
Data from 4 years of 4F-PCC orders were obtained from the laboratory information system, and electronic health records of patients receiving concentrate were reviewed.

Results
4F-PCC was ordered for 427 patients with warfarin-, apixaban-, or rivaroxaban-associated hemorrhage. Turnaround time (TAT) to prepare 4F-PCC was longer when PA-recommended dose adjustments were needed (85 vs 66 minutes, P = .03). There was no difference in TAT between patients who died and those who were ultimately discharged (60 vs 70, P = .22). TAT was shortest for orders originating in the emergency department (ED) compared with other locations (64 vs 85, P &lt; .001), and ED TAT was not associated with patient outcomes in ED patients. PA and dose adjustments reduced amounts of concentrate issued by 27 IU per dose (P = .01). Median international normalized ratio less than 1.3 after 4F-PCC transfusion was achieved for all anticoagulants after dose adjustments. PA did not affect order cancellation or product wastage rates.

Conclusions
PA can ensure 4F-PCC is dosed appropriately without affecting patient outcomes.
Trait Impulsivity Impedes Maturing Out of Problem Drinking Among Socially Anxious Undergraduates
Authors: Bilevicius Elena , Van Landeghem Chantal , Stewart Sherry H , Sherry Simon B , Keough Matthew T 
Published: October 2020

Abstract

Aims
Alcohol use follows a developmental trajectory—steadily increasing and peaking in the early stages of emerging adulthood (e.g. first year of university) and declining thereafter. While most individuals ‘mature out’ of problem drinking as they move through emerging adulthood, some continue to drink heavily and experience serious problems. Tension reduction theory identifies social anxiety (SA) as a potential risk factor for problem drinking during emerging adulthood. However, mixed data suggest that the associations between SA and drinking behaviours are not straightforward. Cross-sectional studies demonstrate that socially anxious emerging adults are at risk for problem drinking, but only if they are also high in trait impulsivity. This study aimed to expand on previous work by examining trait impulsivity as moderator of the prospective associations between SA and maturing out of problem drinking in emerging adulthood.

Methods
Undergraduates (N = 302) completed online self-reports at regular intervals (6-months) over an 18-month period, resulting in four waves of data.

Results
Unconditional latent growth curve models indicated that alcohol problems (but not use) declined linearly over time. Next, conditional growth curve models revealed that SA was associated with impeded maturing out of alcohol problems, but this effect was only present in socially anxious participants with high levels of trait impulsivity.

Conclusion
Our study advances growing literature on the crucial moderating role that impulsivity plays in the SA pathway to problem drinking. Clinical interventions for problem drinking among socially anxious students should both assess for and target concurrent impulsivity.
Work Exposure to VOC in Storage Areas of Retail Stores
Authors: Robert Laurence , Guichard Romain , Klingler Jennifer 
Published: October 2020

Abstract
Poor indoor air quality (IAQ) has been linked to airway disease and early deaths. The ESQUISSE study of IAQ conducted by the French Research and Safety Institute (INRS), characterized the concentrations of various volatile organic compounds (VOCs) in 10 retail stores and storage areas. The IAQ was generally better in sales areas than storage areas, which are more often unventilated and overloaded with new products. For example, in clothing stores, formaldehyde concentrations between 29.0 and 45.0 µg m−3 were measured in non-ventilated storage areas located in the basement; in sales areas, concentrations did not exceed 10.2 µg m−3. Similarly, total VOC (TVOC) concentrations in the two main storage areas were 1153 and 1223 µg m−3 toluene equivalent, whereas they were less than 77.0 µg m−3 toluene equivalent in all sales areas. Many employees work in these high-exposure areas either temporarily or for the entire day, unpacking boxes, placing products on shelves, or collecting products. Reporting primarily on formaldehyde, toluene, or TVOC concentrations, this article shows, in addition to the distinction between sales and storage areas, how an unpacking task can affect an employee’s exposure, and an example of the impact of ambient temperature on VOC concentrations. The results presented clearly highlight the issue of occupational exposure of workers in storage areas.
Cognitive Assessment via Telephone: A Scoping Review of Instruments
Authors: Carlew Anne R , Fatima Hudaisa , Livingstone Julia R , Reese Caitlin , Lacritz Laura , Pendergrass Cody , Bailey Kenneth Chase , Presley Chase , Mokhtari Ben , Cullum Colin Munro 
Published: October 2020

AbstractObjectiveTelephone-based cognitive assessment (TBCA) has long been studied but less widely adopted in routine neuropsychological practice. Increased interest in remote neuropsychological assessment techniques in the face of the coronavirus 2019 (COVID-19) pandemic warrants an updated review of relevant remote assessment literature. While recent reviews of videoconference-based neuropsychological applications have been published, no updated compilation of empirical TBCA research has been completed. Therefore, this scoping review offers relevant empirical research to inform clinical decision-making specific to teleneuropsychology.MethodPeer-reviewed studies addressing TBCA were included. Broad search terms were related to telephone, cognitive, or neuropsychological assessment and screening. After systematic searching of the PubMed and EBSCO databases, 139 relevant articles were retained.ResultsIn total, 17 unique cognitive screening measures, 20 cognitive batteries, and 6 single-task measures were identified as being developed or adapted specifically for telephone administration. Tables summarizing the identified cognitive assessments, information on diagnostic accuracy, and comparisons to face-to-face cognitive assessment are included in supplementary materials.ConclusionsOverall, literature suggests that TBCA is a viable modality for identifying cognitive impairment in various populations. However, the mode of assessment selected clinically should reflect an understanding of the purpose, evidence, and limitations for various tests and populations. Most identified measures were developed for research application to support gross cognitive characterization and to help determine when more comprehensive testing was needed. While TBCA is not meant to replace gold-standard, face-to-face evaluation, if appropriately utilized, it can expand scope of practice, particularly when barriers to standard neuropsychological assessment occur.
Severe acute respiratory syndrome coronavirus 2 indirectly damages kidney structures
Authors: Dargelos Mathilde , Couturier Aymeric , Ferlicot Sophie , Goujon Jean-Michel , Roque-Afonso Anne-Marie , Gault Elyanne , Touchard Guy , Ory Cecile , Kaaki Sihem , Vilaine Eve , Essig Marie , Massy Ziad A 
Published: October 2020

Abstract

Background
The objectives were to characterize Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease 2019 (COVID-19) in patients with acute kidney injury (AKI).

Methods
Kidney biopsy samples in two Caucasian patients and one African with COVID-19 AKI were investigated.

Results
All patients had a high-level non-selective glomerular proteinuria. SARS-CoV-2 samples by real-time polymerase chain reaction (RT- PCR) assay were all-negative, as well as for virus particles in the kidney by electron microscopy. The three patients and patients with other AKI did not differ significantly with regard to angiotensin-converting enzyme 2 and transmembrane protease serine 2 kidney staining.

Conclusions
The kidney damage particularly in Caucasians in COVID-19 seems to be an AKI, possibly by the systemic inflammatory response.
Proactive machine-learning-based approaches to vaccine hesitancy for a potential SARS-Cov-2 vaccine
Authors: Oreskovic T , Kujundzic TIljak M 
Published: October 2020

Abstract

Background
Polls in the US and France found a concerning share of respondents (50% and 26%, respectively) stating that they are not committed to receiving or simply saying they would not accept vaccination against SARS-CoV-2[1][2]. In this context, it is worth revisiting machine-learning approaches to predicting vaccine hesitancy - such as the one developed for MMR vaccination at the individual level by Bell et al.[4] amid Europe's recent measles epidemic - as a first step of a proactive policy.

Proposed Methods and Expectations
In the MMR case, using 44K child-healthcare records including vaccination data, a LASSO logistic regression based on a low number of attributes of the child and his or her family and community produced risk scores, making them readily interpretable by healthcare professionals. Since children are regularly the target population for immunization efforts, recent pediatric and school-age records, in concert with other social and medical features, could provide suitable input for algorithms estimating the probability of refusal of a SARS-Cov-2 vaccine for other members of a household. This is contingent upon data on acceptance and refusal being collected and paired with these inputs in areas where the vaccine will first be deployed (if developed), which gives another argument for such timely and organized data collection. Speculating about the future performance of a new model trained on truly “out of sample” data specific to a novel problem should be avoided. Benchmarks for success in terms of measures such as precision and recall, however, have to be set in light of the gravity of the issue and other available methods. Finally, any model trained with the aim of predicting vaccine hesitancy for a SARS-Cov-2 vaccine should be coupled with tailored communication policies tested as part of the first vaccination efforts. Cornwall, Science Mag, Jun 30, 2020Peretti-Watel et al., The Lancet, May 20, 2020Bell et al., IEEE ICHI, 2019

Key messages
Data on acceptance and refusal for the first (potential) SARS-Cov-2 vaccination campaigns should be collected and matched with health records to enable models predicting vaccine hesitancy. The output of machine learning models predicting vaccine hesitancy should be paired with tested policies respectfully communicating reliable information on vaccination.
End-of-life decisions and appropriateness of care in intensive care: a cross-sectional, pilot study
Authors: Cescon F , Monaco E , Gregori D , Martinato M 
Published: October 2020

Abstract
In Intensive Care Units (ICUs) patients can experience severe organ failures. In several cases, failures can be incurable, making many of the treatments inappropriate, according to ethical principles. Based on the current legislation, in ICUs, clinicians proceed to limit life support care in most of the cases described. Despite this, some studies report that in many cases the care provided is inappropriate for the prognosis. The study aims at investigating the type and frequency of healthcare personnel's End of Life Decisions (DEL) and the point of view of patients' family, contributing to the debate.
A non-interventional cross-sectional pilot study was conducted in 3 ICUs in North-Eastern Italy. Two questionnaires were administered: the first investigates DEL and the perception of nurses and physicians regarding the inadequacy of care provided to patients (from the ELDY study), the second focuses on the family's opinions. Data are expressed by frequencies, percentages, means and standard deviations.
In line with most of previous studies, cases identified as DEL are all related to non-treatment decisions (n = 20, 74%), 44% of these are related to having stopped or not started treatments already knowing the possibility of anticipating the end of life of the patient, while 27% had the precise intention of shortening life. The situation has been discussed with patient's relatives only in two cases. The cause of increased inappropriateness (87%) was the perception that other patients would benefit more from intensive care than the patient in charge, and 40% of the healthcare personnel reported that similar situations occur very frequently.
The restriction of treatment has been confirmed as the most frequent DEL, and interruption being more frequent than non-implementation. Given the high rate of inappropriate care, it could be effective to follow adequate guidelines in the management of the DEL and discuss strategies within the team and with patients' family.

Key messages
When severe organ failures are incurable, in ICUs clinicians proceed to limit life support to the patient in charge. Despite this, in many cases the care provided is inappropriate for the prognosis. Given the high rate of inappropriate care, it could be effective to follow adequate guidelines in the management of the DEL and discuss strategies within the team and with patients’ family.
Public Policies for making the right to life effective: The problem of suicide at ‘Third Bridge'
Authors: Maia A C A , Fabriz D C , Motta T A , Zanotelli V F 
Published: October 2020

Abstract
The World Health Organization (WHO) recognizes suicide as a public health priority. According to the same, between 2010 and 2016 the suicide rate in Brazil increased about 7%, in contrast to the world index, wich fell 9,8%. In the state of Espírito Santo - ES (estimated population of 4 million people), the number of suicide events reached 233 in 2018, the highest rate ever recorded by Datasus Mortality Monitoring Panel to the state. Suicides on public venues are noteworthy. According to data from the Rodovia do Sol Concessionaire (Rodosol), in 2018 about 41% of suicides in this state occured in metropolitan region of Vitória (estimated population of 2 million people). In Deputado Darcy Castello de Mendonça bridge, popularly known as Third Bridge, 71 attemps were counted, of wich 7 culminated in suicide. As a point of concern, this bridge, main link between the cities of Vitória and Vila Velha, has a contingency plan for emergency and crisis situations since 2016, in addition to cameras monitored by a prepared team that work together with a firefighter's team allocated near the bridge to intervene at any time of the day. The monitoring of the situation makes it possible to verify that, since 1999, the suicides that have occurred add up to lower rates in relation to the attempts. However, there was an increase of approximately 44% in the number of people who attempted suicide in the period from 2015 to 2018. Knowing that interventions to prevent suicide include reducing access to lethal means, it stands out that in 2019 a plan to build a protection net in Third Bridge was approved by the government. These strategies, combined to provided health care from the State Hospital of Clinical Attention and suicide preventive measures from public healthcare system SUS, are in accordance with Brazilian's public health policies. It is a recognition, by the state, that the life of the individual has a public significance, and should be protected even from the individual itself.

Key messages
Interventions to prevent suicide must include reducing access to lethal means, that is knowingly a highly effective preventive practice and is responsibility of public policies of a country/state. Knowing that life has a public and political dimension, the suicide barrier implementation is necessary for the State to fulfill its duty to protect the life of the citizen.