bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrical properties enhancement of Liquid and Polymer Gel based electrolytes used for DSSC applications
Authors: Abrol Shivani Arora , Bhargava Cherry , Sharma Pardeep Kumar 
Published: October 2020

Abstract
Electrolytes have been considered a major component of DSSC and play a vital role in determining the ionic conductivity and efficiency of the cell. Emphasis was laid on the confirming the conductivity upon fabrication of an electrolyte using in situ gelation process from a newfangled combination of Triiodide (KI/I2/Glacial acetic acid/distilled water) and gel-based polymer electrolyte (Gelator: PMMA/THF/PC/EC) in the ratio 8:2. The electrolyte portion so framed generated a photo conversion efficiency of 11.32% and a fill factor of 0.439. The conductivity of the sample characterized by Scanning Electron Microscopy showed that the uniform tracks confirmed extreme ionic conductivity of the blend electrolyte which showed dependance on the layered movement of PMMA- co- THF- KI2/PC/EC based electrolyte system. Energy Dispersive x-ray Analysis (EDX) reports engrained the percentage weight proportions of conductive elements (C & O with a wt% of 65.48 and 30.18 in one spectrum and K & I with a wt% of 44.7 & 35.25 in another spectrum respectively). FTIR test analysis was performed to identify the functional groups of the PGE which identified the ionic conductivity of the sample, shown by the intensity of peak absorbance in the range 400–4000 cm−1. Further it was observed, the conductivity of the different concentrations of the liquid and gelator solution demonstrated an increase in exhibiting ionic conductivity and the same was depicted by the morphological studies that featured dark pores of the sample which were spread consistently indicating the amorphous nature of the material (at room temperature).
Fine-Needle Aspiration Biopsy of Intraocular Mass-Like Lesions
Authors: Wang Minhua , Levy Gillian , Qin Xiaoyi , Adeniran Adebowale J , Cai Guoping 
Published: October 2020

AbstractObjectivesThe purpose of this study was to evaluate the diagnostic performance of fine-needle aspiration (FNA) biopsy for intraocular mass-like lesions and its contributing factors.MethodsIntraocular FNA cases were retrieved and reviewed along with histopathologic follow-ups, if available. The effects of rapid on-site evaluation (ROSE), repeated biopsy, and adjunct immunocytochemical studies on cytologic diagnoses were analyzed.ResultsOf 72 FNA biopsies from 63 patients, nondiagnostic biopsy was seen in 17 cases (24%), whereas a definitive diagnosis was rendered in 39 cases (54%). The cytologic diagnoses correlated well with histopathologic follow-ups with a concordance rate of 61%. Almost all nondiagnostic biopsies (16/17, 94%) were seen in cases in which ROSE was not performed. Of the 7 patients in whom biopsy was repeated, a definitive diagnosis was rendered in 4 cases (57%). Immunocytochemistry was performed in the majority of cases with a malignant diagnosis, especially in metastatic tumors (75%).ConclusionsOur data demonstrates that FNA is an effective tool for the diagnosis of intraocular tumors. ROSE, repeated biopsy, and adjunct immunocytochemistry can help reduce the nondiagnostic rate and/or enhance diagnosis of malignancy, further improving FNA diagnostic performance.
Management Policies for Invasive Alien Species: Addressing the Impacts Rather than the Species
Authors: García-Díaz Pablo , Cassey Phillip , Norbury Grant , Lambin Xavier , Montti Lía , Pizarro J Cristóbal , Powell Priscila A , Burslem David F R P , Cava Mário , Damasceno Gabriella , Fasola Laura , Fidelis Alessandra , Huerta Magdalena F , Langdon Bárbara , Linardaki Eirini , Moyano Jaime , Núñez Martín A , Pauchard Aníbal , Phimister Euan , Raffo Eduardo , Roesler Ignacio , Rodríguez-Jorquera Ignacio , Tomasevic Jorge A 
Published: October 2020

AbstractEffective long-term management is needed to address the impacts of invasive alien species (IAS) that cannot be eradicated. We describe the fundamental characteristics of long-term management policies for IAS, diagnose a major shortcoming, and outline how to produce effective IAS management. Key international and transnational management policies conflate addressing IAS impacts with controlling IAS populations. This serious purpose–implementation gap can preclude the development of broader portfolios of interventions to tackle IAS impacts. We posit that IAS management strategies should directly address impacts via impact-based interventions, and we propose six criteria to inform the choice of these interventions. We review examples of interventions focused on tackling IAS impacts, including IAS control, which reveal the range of interventions available and their varying effectiveness in counteracting IAS impacts. As the impacts caused by IAS increase globally, stakeholders need to have access to a broader and more effective set of tools to respond.
Crossing the chasm: caution for use of angiotensin receptor-neprilysin inhibition in patients with cardiogenic shock– a case report
Authors: Almazroa Loai , Mihajlovic Vesna , Lawler Patrick R. , Luk Adriana 
Published: October 2020

Abstract

Background
Vasoplegia has been reported in patients receiving angiotensin receptor-neprilysin inhibitors (ARNI) with heart failure with reduced ejection fraction (HFrEF). We present a case of vasoplegic shock after initiation of ARNI in a hospitalized 65-year-old man recovering from cardiogenic shock (CS) and acute kidney injury (AKI).

Case summary
A 65-year-old man with HFrEF presented to a community hospital with CS with evidence of poor perfusion with a lactate of 5.6 mmol/L and creatinine (Cr) 125 µmol/L. He was treated with intravenous furosemide infusion. Subsequently, his lactate normalized but he developed an AKI with a Cr of 176 µmol/L. He was then started on ARNI and beta blockers. Over the next 24 h, he developed a vasoplegic shock necessitating multiple vasopressors and a transfer to a tertiary academic centre. With supportive therapy, his vasoplegic shock improved and he was discharged home.

Discussion
PARADIGM-HF found that the introduction of an ARNI in patients with ambulatory symptomatic HFrEF reduces the risk of death and heart failure hospitalization. Most recently, PIONEER-HF showed that ARNI reduced N-terminal pro-B-type natriuretic peptide levels at 4 and 8 weeks, without significantly different rates of medication-related adverse effects. However, thus far, no clinical trials have examined the role of ARNI in CS. Our case report highlights the risk of vasoplegic shock caused by initiation of ARNI in patients hospitalized with CS especially in whom renal and hepatic impairment is present.
Occlusal traits and longitudinal dental changes in children and adolescents with congenital or childhood onset myotonic dystrophy
Authors: Fontinha Clara , Engvall Monica , Sjögreen Lotta , Mårtensson Åsa , Ekström Anne-Berit , Kiliaridis Stavros 
Published: October 2020

Summary

Background/objectives
This research aimed to study the malocclusions of children and adolescents with myotonic dystrophy type 1 (DM1), in respect to healthy individuals, and trace the occlusal changes that occurred in these individuals during growth.

Materials/methods
Thirty-six dental casts, from children and adolescents with DM1 living in western and southern Sweden, were compared with a control group of 50 healthy individuals. To identify potential changes in occlusal traits, 26 casts were assessed and followed-up over a median time of 9 years. Independent samples t-tests were used to compare the two groups and their changes over time. Paired samples t-tests tested changes over time within each group (P &lt; 0.05).

Results
DM1 patients had a higher prevalence of anterior open bite, posterior crossbite, and Class III malocclusions. When compared to controls, patients presented smaller upper and lower intermolar as well as intercanine widths. In both groups, the individuals revealed longitudinal changes with a decrease in both upper and lower arch lengths and an increase on the palatal vault height. During the follow-up period, the prevalence of malocclusions remained almost the same, only significantly differing regarding the changes that occurred between groups referred to the upper intermolar width, which decreased among DM1 patients.

Conclusions/implications
In comparison to healthy controls, children and adolescents with DM1 have shown already at an early age a higher prevalence of both anterior open bite and posterior crossbite. These occlusal traits did not change with time apart from the upper narrow intermolar width, which further decreased with time.
Quality improvement in chronic care by self-audit, benchmarking and networking in general practices in South Tyrol, Italy: results from an interventional study
Authors: Piccoliori Giuliano , Mahlknecht Angelika , Abuzahra Muna E , Engl Adolf , Breitenberger Vera , Vögele Anna , Montalbano Carmelo , Sönnichsen Andreas 
Published: October 2020

AbstractBackgroundSystematic strategies promoting quality of care in general practice are yet under-represented in several European countries.ObjectiveThis interventional study assessed whether a combined intervention (self-audit, benchmarking, quality circles) improved quality of care in Salzburg, Austria and South Tyrol, Italy. The present publication reports the Italian results.MethodsWe developed quality indicators for general practice in a consensus process based on pre-existing quality programmes. The indicators addressed diagnosis and treatment regarding eight common chronic conditions. A quality score comprising 91 indicators was calculated (0–5 points per indicator depending on fulfilment, maximum 455 points). We collected anonymous data from the electronic health records of the participating physicians in 2012, 2013 and 2014. Wilcoxon signed-rank tests were used for pre-post analysis.ResultsThirty-six GPs participated in the study. The median quality score increased significantly from 177.0 points at baseline to 272.0 points at the second follow-up (P = 0.000). Improvements concerned process and intermediate outcome indicators particularly between baseline and the first follow-up.ConclusionPerformance was relatively low at baseline and improved considerably, mainly in the first study period. The intervention investigated in this study can serve as a model for future quality programmes. A customized electronic health record for the implementation of this intervention as well as standardized and consistent documentation by GPs is a prerequisite. Use of a limited set of quality indicators (QIs) and regular QI modification is probably advisable to increase the benefits. Long-term prospective studies should investigate the impact of QI-based interventions on end-result outcomes.
Developing the use of convolutional neural networking in benthic habitat classification and species distribution modelling
Authors: Fincham Jennifer I , Wilson Christian , Barry Jon , Bolam Stefan , French Geoffrey 
Published: October 2020

Abstract
Management of the marine environment is increasingly being conducted in accordance with an ecosystem-based approach, which requires an integrated approach to monitoring. Simultaneous acquisition of the different data types needed is often difficult, largely due to specific gear requirements (grabs, trawls, and video and acoustic approaches) and mismatches in their spatial and temporal scales. We present an example to resolve this using a convolutional neural network (CNN), using ad hoc multibeam data collected during multi-disciplinary surveys to predict the distribution of seabed habitats across the western English Channel. We adopted a habitat classification system, based on seabed morphology and sediment dynamics, and trained a CNN to label images generated from the multibeam data. The probability of the correct classification by the CNN varied per habitat, with accuracy above 60% for 85% of habitats in a training dataset. Statistical testing revealed that the spatial distribution of 57 of the 100 demersal fish and shellfish species sampled across the region during the surveys possessed a non-random relationship with the multibeam-derived habitats using CNN. CNNs, therefore, offer the potential to aid habitat mapping and facilitate species distribution modelling at the large spatial scales required under an ecosystem-based management framework.
Congenital atresia of the left main coronary artery: management of a 5-year-old child in extremis
Authors: Schmiady Martin , Kretschmar Oliver , Prêtre René , Dave Hitendu 
Published: October 2020

Abstract
Atresia of the left main coronary artery is a rare coronary anomaly. We describe the case of a 5-year-old child presenting in emergency in extremis. Clinical findings of haemodynamic collapse, malignant ventricular tachyarrhythmias and severe mitral regurgitation were indicative of a possible ischaemic aetiology. Surgical revascularization of the atretic left main coronary artery segment using an interposition autologous saphenous vein graft was successfully performed.
Early commercial experience with a newly designed balloon-expandable transcatheter heart valve: 30-day outcomes and implications of preprocedural computed tomography
Authors: Schaefer Andreas , Plassmeier Fabienne , Schofer Niklas , Vogel Lukas , Ludwig Sebastian , Schneeberger Yvonne , Linder Matthias , Demal Till , Seiffert Moritz , Blankenberg Stefan , Reichenspurner Hermann , Westermann Dirk , Conradi Lenard 
Published: October 2020

Abstract

OBJECTIVES
We herein report a single-centre experience with the SAPIEN 3 Ultra balloon-expandable transcatheter aortic valve implantation (TAVI) system.

METHODS
Between March 2019 and January 2020, a total of 79 consecutive patients received transfemoral TAVI using the SAPIEN 3 Ultra device. Data were retrospectively analysed according to updated Valve Academic Research Consortium-2 definitions. Detailed analysis of multislice computed tomography data was conducted to identify potential predictors for permanent pacemaker (PPM) implantation and residual paravalvular leakage (PVL) post TAVI.

RESULTS
Device success and early safety were 97.5% (77/79) and 94.9% (75/79) with resulting transvalvular peak/mean pressure gradients of 21.1 ± 8.2/10.9 ± 4.4 and PVL &gt;mild in 0/79 patients (0%). Mild PVL was seen in 18.9% (15/79) of cases. Thirty-day mortality was 2.5% (2/79). The Valve Academic Research Consortium-2 adjudicated clinical end points disabling stroke, acute kidney injury and myocardial infarction occurred in 1.3% (1/79), 5.1% (4/79) and 0% (0/79) of patients. Postprocedural PPM implantation was necessary in 7.6% (6/79) of patients. Multislice computed tomography analysis revealed significantly higher calcium amounts of the right coronary cusp in patients in need for postprocedural PPM implantation and a higher eccentricity index in patients with postinterventional mild PVL.

CONCLUSIONS
First experience with this newly designed balloon-expandable-transcatheter heart valve demonstrates adequate 30-day outcomes and haemodynamic results with low mortality, low rates of PPM implantation and no residual PVL &gt;mild. The herein-presented multislice computed tomography values with an elevated risk for PPM implantation and residual mild PVL may help to further improve outcomes with this particular transcatheter heart valve in TAVI procedures.
Emergency treatment of bleeding hemorrhoids in a patient taking aspirin and clopidogrel using a 1470 nm diode laser and the ELITE minimal invasive technique
Authors: Bachtsetzis Chris , Papaioannou Antigoni , Bekas Spyridon , Lazaridou Athina , Bachtsetzis George 
Published: October 2020

Abstract
A 74-year-old male patient, receiving anticoagulation treatment after previous angioplasty stenting for severe coronary artery disease, was admitted to the clinic with a 2-day rectal bleeding. Clinical examination followed by an urgent colonoscopy to exclude other potential reasons for his symptoms both confirmed the diagnosis of Grade III thrombosed hemorrhoids. Due to the acute presentation of the case along with the existing medication of the patient, the decision was made to treat the problem using the expert laser intrahemorrhoidal therapy technique, which is a diode laser minimally invasive operation without the need to stop any of the patient’s medication.
Temporal dynamics of QTL effects on vegetative growth inArabidopsis thaliana
Authors: Meyer Rhonda C , Weigelt-Fischer Kathleen , Knoch Dominic , Heuermann Marc , Zhao Yusheng , Altmann Thomas 
Published: October 2020

AbstractWe assessed early vegetative growth in a population of 382 accessions of Arabidopsis thaliana using automated non-invasive high-throughput phenotyping. All accessions were imaged daily from 7 d to 18 d after sowing in three independent experiments and genotyped using the Affymetrix 250k SNP array. Projected leaf area (PLA) was derived from image analysis and used to calculate relative growth rates (RGRs). In addition, initial seed size was determined. The generated datasets were used jointly for a genome-wide association study that identified 238 marker–trait associations (MTAs) individually explaining up to 8% of the total phenotypic variation. Co-localization of MTAs occurred at 33 genomic positions. At 21 of these positions, sequential co-localization of MTAs for 2–9 consecutive days was observed. The detected MTAs for PLA and RGR could be grouped according to their temporal expression patterns, emphasizing that temporal variation of MTA action can be observed even during the vegetative growth phase, a period of continuous formation and enlargement of seemingly similar rosette leaves. This indicates that causal genes may be differentially expressed in successive periods. Analyses of the temporal dynamics of biological processes are needed to gain important insight into the molecular mechanisms of growth-controlling processes in plants.
Plant functional trait variability and trait syndromes among wheat varieties: the footprint of artificial selection
Authors: Cantarel Amélie A M , Allard Vincent , Andrieu Bruno , Barot Sébastien , Enjalbert Jérôme , Gervaix Jonathan , Goldringer Isabelle , Pommier Thomas , Saint-Jean Sébastien , Le Roux Xavier 
Published: October 2020

AbstractAlthough widely used in ecology, trait-based approaches are seldom used to study agroecosystems. In particular, there is a need to evaluate how functional trait variability among varieties of a crop species compares to the variability among wild plant species and how variety selection can modify trait syndromes. Here, we quantified 18 above- and below-ground functional traits for 57 varieties of common wheat representative of different modern selection histories. We compared trait variability among varieties and among Pooideae species, and analyzed the effect of selection histories on trait values and trait syndromes. For traits under strong selection, trait variability among varieties was less than 10% of the variability observed among Pooideae species. However, for traits not directly selected, such as root N uptake capacity, the variability was up to 75% of the variability among Pooideae species. Ammonium absorption capacity by roots was counter-selected for conventional varieties compared with organic varieties and landraces. Artificial selection also altered some trait syndromes classically reported for Pooideae. Identifying traits that have high or low variability among varieties and characterizing the hidden effects of selection on trait values and syndromes will benefit the selection of varieties to be used especially for lower N input agroecosystems.
Migration as Adaptation?
Authors: Vinke Kira , Bergmann Jonas , Blocher Julia , Upadhyay Himani , Hoffmann Roman 
Published: October 2020

AbstractThe discourse on climate change and migration has shifted from labelling migration merely as a consequence of climate impacts, to describing it as a form of human adaptation. This article explores the adaptation framing of the climate change and migration nexus and highlights its shortcomings and advantages. While for some groups, under certain circumstances migration can be an effective form of adaptation, for others it leads to increased vulnerabilities and a poverty spiral, reducing their adaptive capacities. Non-economic losses connected to a change of place further challenge the notion of successful adaptation. Even when migration improves the situation of a household, it may conceal the lack of action on climate change adaptation from national governments or the international community. Given the growing body of evidence on the diverse circumstances and outcomes of migration in the context of climate change, we distinguish between reactive and proactive migration and argue for a precise differentiation in the academic debate.
jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population
Authors: Tadaka Shu , Hishinuma Eiji , Komaki Shohei , Motoike Ikuko N , Kawashima Junko , Saigusa Daisuke , Inoue Jin , Takayama Jun , Okamura Yasunobu , Aoki Yuichi , Shirota Matsuyuki , Otsuki Akihito , Katsuoka Fumiki , Shimizu Atsushi , Tamiya Gen , Koshiba Seizo , Sasaki Makoto , Yamamoto Masayuki , Kinoshita Kengo 
Published: October 2020

Abstract
In the Tohoku Medical Megabank project, genome and omics analyses of participants in two cohort studies were performed. A part of the data is available at the Japanese Multi Omics Reference Panel (jMorp; https://jmorp.megabank.tohoku.ac.jp) as a web-based database, as reported in our previous manuscript published in Nucleic Acid Research in 2018. At that time, jMorp mainly consisted of metabolome data; however, now genome, methylome, and transcriptome data have been integrated in addition to the enhancement of the number of samples for the metabolome data. For genomic data, jMorp provides a Japanese reference sequence obtained using de novo assembly of sequences from three Japanese individuals and allele frequencies obtained using whole-genome sequencing of 8,380 Japanese individuals. In addition, the omics data include methylome and transcriptome data from ∼300 samples and distribution of concentrations of more than 755 metabolites obtained using high-throughput nuclear magnetic resonance and high-sensitivity mass spectrometry. In summary, jMorp now provides four different kinds of omics data (genome, methylome, transcriptome, and metabolome), with a user-friendly web interface. This will be a useful scientific data resource on the general population for the discovery of disease biomarkers and personalized disease prevention and early diagnosis.