The IBD-disk Is a Reliable Tool to Assess the Daily-life Burden of Patients with Inflammatory Bowel Disease
Authors: Tadbiri Sara , Nachury Maria , Bouhnik Yoram , Serrero Melanie , Hébuterne Xavier , Roblin Xavier , Kirchgesner Julien , Bouguen Guillaume , Franchimont Denis , Savoye Guillaume , Buisson Anthony , Louis Edouard , Nancey Stephane , ABitbol Vered , Reimund Jean-Marie , DeWit Olivier , Vuitton Lucine , Matthieu Nicolas , Peyrin-Biroulet Laurent , Gilletta Cyrielle , Allez Matthieu , Viennot Stephanie , Trang-Poisson Caroline , Dib Nina , Brixi Hedia , Boualit Medina , Plastaras Laurianne , Boivineau Lucile , Fumery Mathurin , Caillo Ludovic , Laharie David , Amiot Aurelien ,   GETAID-IBD-disk study group, Amiot Aurelien , Tadbiri Sara , Gagniere Charlotte , Tannoury Jenny , Nachury Maria , Pariente Benjamin , Wils Pauline , Bouhnik Yoram , Stefanescu Carmen , Treton Xavier , Serrero Melanie , Filippi Jerome , Hébuterne Xavier , Arab Nadia , Cluzeau Virginie , Roblin Xavier , Del Tedesco Emilie , Beaugerie Laurent , Seksik Philippe , Bourrier Anne , Landmann Cecilia , Kirchgesner Julien , Sokol Harry , Bouguen Guillaume , Siproudhis Laurent , DeWit Marie , Franchimont Denis , Savoye Guillaume , Buisson Anthony , Louis Edouard , Reenaers Catherine , Nancey Stephane , Boschetti Gilles , Gay Claire , Danion Pauline , Flourié Bernard , Abitbol Vered , Malamut Georgia , Reimund Jean-Marie , Caron Benedicte , DeWit Olivier , Vuitton Lucine , Mathieu Nicolas , Pestour Sandie , Peyrin-Biroulet Laurent , Zallot Camille , Gilletta Cyrielle , Allez Matthieu , Gornet Jean-Marc , Baudry Clotilde , Viennot Stephanie , Bourreille Arnaud , Trang-Poisson Caroline , Dib Nina , Brixi Hedi , Cadiot Guillaume , Boualit Medina , Painchart Claire , Plastaras Laurianne , Boivineau Lucile , Altwegg Romain , Fumery Mathurin , Caillo Ludovic , Laharie David , Riviere Pauline , Poullenot Florian , Coffin Benoit , Duboc Henri , Nahon Stephane , Tavernier Noemie , Simon Marion , Coulibaly Baya , Amil Morgane , Nicolas Duveau , Khater Sherine , Kaassis Mehdi , Goutorbe Felix , Moussata Driffa , Picon Laurence 
Published: November 2020

Abstract

Background and Aim
The inflammatory bowel disease [IBD]-disk is a 10-item self-questionnaire that is used to assess IBD-related disability. The aim of the present study was to evaluate this tool in the assessment of IBD daily-life burden.

Methods
A 1-week cross-sectional study was conducted in 42 centres affiliated in France and Belgium. Patients were asked to complete the IBD-disk [best score: 0, worst score: 100] and a visual analogue scale [VAS] of IBD daily-life burden [best score: 0, worst score: 10]. Analyses included internal consistency, correlation analysis, and diagnostic performance assessment.

Results
Among the 2011 IBD outpatients who responded to the survey [67.8% of the patients had Crohn’s disease], 49.9% were in clinical remission. The IBD-disk completion rate was 73.8%. The final analysis was conducted in this population [n = 1455 patients]. The mean IBD-disk score and IBD daily-life burden VAS were 39.0 ± 23.2 and 5.2 ± 2.9, respectively. The IBD-disk score was well correlated with the IBD daily-life burden VAS [r = 0.67; p &lt;0.001]. At an optimal IBD-disk cut-off of 40, the area under the receiver operating characteristic curve [AUROC] for high IBD daily-life burden [VAS &gt;5] was 0.81 (95% confidence interval [CI]: 0.79–0.83; p &lt;0.001).

Conclusions
In a large cohort of patients, the IBD-disk score was well correlated with IBD daily-life burden, and it could be used in clinical practice.