bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of oncological care pathways in primary and secondary care on patient, professional and health systems outcomes: a systematic review and meta-analysis
Authors: van Hoeve Jolanda C. , Vernooij Robin W. M. , Fiander Michelle , Nieboer Peter , Siesling Sabine , Rotter Thomas 
Published: October 2020

Abstract
Background
Pathways are frequently used to improve care for cancer patients. However, there is little evidence about the effects of pathways used in oncological care. Therefore, we performed a systematic review and meta-analysis aiming to identify and synthesize existing literature on the effects of pathways in oncological care.

Methods
All patients diagnosed with cancer in primary and secondary/tertiary care whose treatment can be characterized as the strategy “care pathways” are included in this review. A systematic search in seven databases was conducted to gather evidence. Studies were screened by two independent reviewers. Study outcomes regarding patients, professionals, and system level were extracted from each study.

Results
Out of 13,847 search results, we selected 158 articles eligible for full text assessment. One hundred fifty studies were excluded and the remaining eight studies represented 4786 patients. Most studies were conducted in secondary/tertiary care. Length of stay (LOS) was the most common used indicator, and was reported in five studies. Meta-analysis based on subgroups showed an overall shorter LOS regarding gastric cancer (weighted mean difference (WMD)): − 2.75, CI: − 4.67 to − 0.83) and gynecological cancer (WMD: − 1.58, CI: − 2.10 to − 1.05). Costs were reported in six studies and most studies reported lower costs for pathway groups.

Conclusions
Despite the differences between the included studies, we were able to present an evidence base for cancer care pathways performed in secondary/tertiary care regarding the positive effects of LOS in favor of cancer care pathways.

Systematic review registration
PROSPERO CRD42017057592.
Breeding ecology of the Yellow-bellied Warbler (Abroscopus superciliaris)
Authors: Bi Jianli , Jiang Yuxin , Yang Canchao 
Published: October 2020

AbstractThe life history of birds dictates their activities and is crucial to population success. However, the life history traits of only one-third of the world’s bird species have been described; the rest are poorly understood. We studied the breeding ecology of the Yellow-bellied Warbler (Abroscopus superciliaris) and documented reproductive information throughout the egg and nestling periods. The data included natural nest sites, nest components, nest size, egg laying dates and time, egg morph, egg size, clutch size, egg incubation, nestling brooding and feeding, nestling morph and growth, and reproductive outcome. This study provided particular information of breeding ecology that has not been reported before in the Yellow-bellied Warbler.
Corticosterone Is Essential for Survival Through Frog Metamorphosis
Authors: Shewade Leena H , Schoephoerster Jamee A , Patmann Matthew D , Kulkarni Saurabh S , Buchholz Daniel R 
Published: October 2020

Abstract
Thyroid hormone (TH) is required for frog metamorphosis, and corticosterone (CORT) increases TH signaling to accelerate metamorphic progression. However, a requirement for CORT in metamorphosis has been difficult to assess prior to the recent development of gene-editing technologies. We addressed this long-standing question using transcription activator-like effector nuclease (TALEN) gene disruption to knock out proopiomelanocortin (pomc) and disrupt CORT production in Xenopus tropicalis. As expected, mutant tadpoles had a reduced peak of plasma CORT at metamorphosis with correspondingly reduced expression of the CORT-response gene Usher syndrome type-1G (ush1g). Mutants had reduced rates of growth and development and exhibited lower expression levels of 2 TH response genes, Krüppel-like factor 9 (klf9) and TH receptor β (thrb). In response to exogenous TH, mutants had reduced TH response gene induction and slower morphological change. Importantly, death invariably occurred during tail resorption, unless rescued by exogenous CORT and, remarkably, by exogenous TH. The ability of exogenous TH by itself to overcome death in pomc mutants indicates that the CORT-dependent increase in TH signaling may ensure functional organ transformation required for survival through metamorphosis and/or may shorten the nonfeeding metamorphic transition to avoid lethal inanition.
Hormonal Stimulation of Human Ovarian Xenografts in Mice: Studying Folliculogenesis, Activation, and Oocyte Maturation
Authors: Wall Monica Anne , Padmanabhan Vasantha , Shikanov Ariella 
Published: October 2020

Abstract
Ovarian tissue cryopreservation and banking provides a fertility preservation option for patients who cannot undergo oocyte retrieval; it is quickly becoming a critical component of assisted reproductive technology programs across the world. While the transplantation of cryopreserved ovarian tissue has resulted in over 130 live births, the field has ample room for technological improvements. Specifically, the functional timeline of grafted tissue and each patient’s probability of achieving pregnancy is largely unpredictable due to patient-to-patient variability in ovarian reserve, lack of a reliable method for quantifying follicle numbers within tissue fragments, potential risk of reintroduction of cancer cells harbored in ovarian tissues, and an inability to control follicle activation rates. This review focuses on one of the most common physiological techniques used to study human ovarian tissue transplantation, xenotransplantation of human ovarian tissue to mice and endeavors to inform future studies by discussing the elements of the xenotransplantation model, challenges unique to the use of human ovarian tissue, and novel tissue engineering techniques currently under investigation.
COMPLICATIONS IN ELDERLY AFTER PROXIMAL FEMORAL FRACTURE: AN INTEGRATING REVIEW
Authors: Sousa Allex Sobral , Sousa Carmelita Maria Silva , Gurgel Lucineide Coqueiro , Queiroz Iasmin Belém Silva , Sousa Francisco Rafael Soares de , Nóbrega Joanacele Gorgonho Ribeiro , Dantas Marta Coêlho Bezerra , Duarte Aclenielle Vital Santana , Luz Dayse Christina Rodrigues Pereira , Santana Willma José de 
Published: October 2020

Abstract: Proximal femoral fractures in the elderly are mainly caused by low energy trauma, often resulting from a fall. Studies demonstrate the growing concern with the functional independence of the elderly due to the high incidence of proximal femoral fracture and its complications. The aim of this study was to identify the main factors associated with proximal femoral fractures (FFP) in the elderly and their consequences for their functional independence. The present study is defined as an integrative review. The search for scientific articles was carried out in the databases LILACS, Medline, SciElo and PubMed, from 2015 to 2019. Inclusion criteria were articles that were entirely available online and in the Portuguese, English and Spanish languages. And articles that were not available in the whole and before 2015 were excluded. In the results, it was identified that proximal femoral fractures are more frequent in the elderly with greater longevity. It has been observed that the appearance of future consequences in the elderly after FFP is often related to the long bedridden periods of this patient, impairing their functional independence. Elderly patients with FFP present a greater predisposition to reduce muscle strength, thus contributing to the appearance of future complications. These factors contribute to the morbidity and increase of the elderly mortality. FFP represent an important factor to lose functional independence in the elderly. Promote the elimination of future complications and their risk factors with therapeutic planning of individual and collective actions aimed at preventing injuries and their consequences, and thus reducing the mortality of this patient.Keywords: Proximal femoral fracture. Elderly. Consequences. Complications.
Formação de pedagogos e pedagogas indígenas: Uma terra de direitos e de resistência
Authors: Gehrke Marcos , Sapelli Marlene Lucia Siebert , Faustino Rosangela Celia 
Published: October 2020

Analisa o processo de construção coletiva do Projeto Político-Pedagógico da Licenciatura em Pedagogia Indígena, da Universidade Estadual do Centro Oeste, em Guarapuava/PR/BR, a partir da apresentação da demanda pela comunidade indígena do Rio das Cobras. Explicita o aparato jurídico-pedagógico acerca do acesso ao ensino superior, do curso de Pedagogia, bem como da formação de professores indígenas. Aduz o processo de construção coletiva do projeto em questão e os diversos sujeitos envolvidos. Apresenta o processo de seleção especial dos candidatos ao curso e o seu perfil. Utiliza a pesquisa bibliográfica, mediada com a análise documental. Consideramos que esse processo instigou o coletivo envolvido a refletir sobre a função social da Universidade pública, que é também aproximar-se do povo, construindo estratégias de acesso e permanência dos sujeitos, especialmente dos grupos minorizados. Entendemos que a consolidação do curso de Pedagogia, atendendo às especificidades culturais e epistemológicas dos indígenas, representa uma forma de resistir, de ocupar a Universidade, garantindo que ela se pinte de povo, que ela, de alguma forma, contribua para fortalecer processos de auto-organização, de formação humana em todas as dimensões, de acesso a diferentes formas de conhecimento, de qualificação profissional, de reavaliação da própria organização do trabalho pedagógico na Universidade.
O povo indígena Apinayé e o acesso à licenciatura em educação do campo da Universidade Federal do Tocantins: Algumas reflexões
Authors: Brasil Anderson , Silva Cícero da 
Published: October 2020

Este artigo objetiva discutir o acesso do povo indígena Apinayé ao curso de Licenciatura em Educação do Campo: Códigos e Linguagens - Artes e Música da Universidade Federal do Tocantins (UFT), Campus de Tocantinópolis, Brasil, bem como dialogar com alguns teóricos contemporâneos (Brandão, 1983; Haesbaert, 2016; Lévi-Strauss, 1973; Nimuendajú, 1956; Santos, 1999) acerca da diversidade sociocultural no Estado do Tocantins. Para tanto, a investigação aborda aspectos de processos seletivos, práticas didático-pedagógicas, linguagem e programas de políticas afirmativas que (des)favorecem o acesso e inclusão/permanência desses estudantes na Universidade. A pesquisa é de natureza bibliográfica e exploratória, de abordagem qualitativo-interpretativista. Desde seu primeiro processo seletivo realizado em 2014, esse curso recebe anualmente alunos ingressantes indígenas Apinayé. Os resultados da investigação mostram que, apesar de a UFT utilizar diferentes ações afirmativas como programas específicos para acolher e dar apoio aos estudantes indígenas e as atividades didático-pedagógicas implementadas em sala de aula no curso Licenciatura em Educação do Campo terem suas especificidades voltadas à formação dos povos do campo, tudo isso não tem sido o suficiente para garantir a inclusão/permanência dos indígenas nesse curso de graduação. E as maiores barreiras enfrentadas pelos Apinayé tem sido a língua portuguesa e a epistemologia da academia.
O Ritual da Festa do Moqueado: Educação, cultura e identidade na sociedade indígena Tembé-Tenetehara
Authors: Miranda Julia Cleide , Borges Carlos Nazareno 
Published: October 2020

O povo indígena Tembé-Tenetehara tradicionalmente pratica o Ritual da Festa do Moqueado que celebra a passagem de meninas e meninos da infância para a vida adulta. Neste ritual estão presentes diversos saberes tradicionais do povo Tembé-Tenetehara. Nossa intenção foi analisar como o Ritual da Festa do Moqueado configura-se em um processo educativo no qual são produzidos, circulam e são apropriados múltiplos saberes contribuindo para a construção da identidade e da cultura indígena Tembé- Tenetehara. A pesquisa se posicionou na abordagem qualitativa e estabeleceu a etnometodologia como seu principal aporte metodológico, utilizando Garfinkel (2006), Coulon (2005). As técnicas de coleta de dados utilizadas foram: observação participante, entrevistas, notas de campo. As principais categorias teóricas utilizadas no trabalho de análise são: educação (Brandão, 2002), cultura (Williams, 2011), ritual (Sagalen, 2002), identidade (Giddens, 2002), e saber (Martinic, 1994). Como resultado do estudo, elucidamos que o Ritual é um processo educativo intencional, com objetivos e objetos de conhecimentos definidos e articulados e que os saberes contidos no Ritual da Festa do Moqueado se traduzem em um processo educativo a medida que são apropriados, assimilados e ressignificados pelos jovens protagonistas sendo determinante para a construção de sua identidade étnica e afirmação de sua cultura.
Pola Penggunanan Balanced Scorcard Pada Indikator Kinerja Utama Universitas Islam Negeri Syarif Hidayatullah Jakarta
Authors: Fitriadi Fitriadi , Sumardjo Mahendro , Jubaedah Jubaedah 
Published: October 2020

Abstract. The research problems about phenomena of the difficulty in seeing performance achievements and performance measurements at State Islamic University (UIN) Syarif Hidayatullah Jakarta. The UIN Syarif Hidayatullah Jakarta has difficulty making decisions in performance management, because before using the KPI, Its used budget management in performance appraisal and measurement. This research uses a qualitative method of field study with a phenomenological approach. Research objects are the experiences of the use of the Balanced Scorecard (BSC) pattern on the KPI of the UIN Syarif Hidayatullah Jakarta in 2018. After its existence of the Main KPI using the BSC. The results of the KPI are taken into consideration for performance evaluation by stakeholders at UIN Syarif Hidayatullah Jakarta in achieving the organization's vision. This performance appraisal and performance measurement can serve as a reference for performance achievements for Higher Education Rankings at the national and international level, Government Institution Performance Accountability Report (LAKIP), Strategic Plan (Renstra) and Campus Development Master Plan (RIBKA) or Milestones by looking at indicators, targets and size of the report.Keywords: Key Performance Indicators (KPI), Key Performance Indicators (KPI), Balanced Scorecard (BSC), Performance Measurement, Cascade. Abstrak. Fenomena yang diteliti pada UIN Syarif Hidayatullah Jakarta adalah sulitnya melihat capaian kinerja dan pengukuran kinerja. Oleh karena itu, UIN Syarif Hidayatullah Jakarta kesulitan mengambil keputusan dalam manajemen kinerja, sebelum menggunakan IKU, UIN Syarif Hidayatullah Jakarta menggunakan manajemen anggaran dalam penilaian dan pengukuran kinerja. Penelitian ini menggunakan metode kualitatif studi lapangan dengan pendekatan fenomenologi. Yang diteliti adalah pengalaman pola penggunaan Balanced Scorecard (BSC) IKU atau Key Performance Indicator (KPI) UIN Syarif Hidayatullah Jakarta tahun 2018. Setelah adanya IKU di UIN Syarif Hidayatullah Jakarta dengan menggunakan Balanced Scorecard (BSC). penilaian kinerja dan ukuran kinerja ini bisa sebagai acuan capaiaan kinerja untuk Perangkingan Perguruan Tinggi di tingkat nasional maupun internasional, Laporan Akuntabilitas Kinerja Instansi Pemerintahan (LAKIP), Rencana Strategis (Renstra) dan Rencana Induk Pengembangan Kampus (RIBKA) atau Milestones dengan melihat indikator, target dan ukuran pada lapran tersebut.Kata Kunci: Indikator Kinerja Utama (IKU), Key Performance Indicator (KPI), Balanced Scorecard (BSC), Pengukuran Kinerja, Cascade.
Dynamics of plant cover of meadow steppes after the cessation of traditional management in Opillia
Authors: Dmytrash-Vatseba I. I. , Shumska N. V. 
Published: October 2020

Meadow steppes of Opillia (western edge of Podillia Upland, Western Ukraine) belong to xerothermic calcareous grasslands which are the most species-rich habitats in Europe. This paper contains results of a nine-year study (2010–2018 years) of plant species composition in ‘Ostrivets’ grassland after the cessation of traditional management (mowing). The patch had been burnt for at least five years running and then abandoned for five more years. The patch was chosen as a model grassland of abandoned meadow steppes. We examined plant species richness and composition on three sample plots of 5 x 5 m2. In 2010, at the beginning of annual burning practice the plots harboured 114 species. One year after cessation of disturbance by fire (2014), species richness decreased to 108 species. In 2018, after five years of abandonment it reached 83 species. Abundance of the dominant species (Brachypodium pinnatum) remained unchanged when the patch was under annual burning regime. After abandonment of the habitat Molinia arundinacea became the dominant species. Species composition experienced changed as well. Only 37.9% of species remained in the sample plots from 2010 till 2018. The proportion of meadow-steppe species halved, they were substituted by species of forests, forest edges and ruderal species. Percent of meadow species did not significantly change, however this group of species began to dominate within the community. The cover of woody vegetation reached 15–20% in 2018. Rubus caesius encroached on the grassland in 2014 and gained 20% of projective cover in 2018. Ten out of thirteen rare species disappeared from the habitat during the study period. ‘Ostrivets’ habitat requires urgent measures to be taken to restore and preserve meadow-steppe species composition. We suggest the following measures: elimination of trees and shrubs, regular moving and overseeding of extinct species.
Antibiofilm forming, antimicrobial activity and some biochemical properties of Vaccinium vitis idaea leaf and berry extracts on Staphylococcus aureus
Authors: Kryvtsova M. V. , Salamon I. , Koscova J. , Spivak M. Y. 
Published: October 2020

Infections caused by Staphylococcus genus bacteria remain a relevant problem due to the high percentage of antibio­tic-resistant biofilm-forming strains of isolates of this genus. Herbs are a promising source for many biologically active compounds with antimicrobial properties. The aim of the research was to study the antimicrobial and antibiofilm formation activity of berry and leaf extracts of Vaccinium vitis-idaea L. upon clinical isolates of S. aureus, and the main biochemical properties of these extracts. For the purpose of analysis, we used S. aureus isolated from the mouth cavities and pharynx of human patients suffering from inflammatory diseases. The plants for the study were gathered in Pylypets, Mizhhiria rayon, Zakarpatska oblast (Transcarpathia). From Vaccinium vitis-idaea L., leaf and berry extracts were produced. To determine the chemical properties of the extracts, the following constituents were investigated: total tannin, flavonoids, total phenols, anthocyanins (by spectrophotometric method), and the total amount of vitamin C in berry extract (chromatographically). The antimicrobial activity was studied by diffusion-into-agar method and determination of minimum inhibitory concentrations. The antibiofilm activity of the extracts was tested in standard 96-well microtitration plates. The main chemical composition of ethyl extracts of Vaccinium vitis-idaea L. berries and leaves was identified. The level of tannins in leaf extracts was established to be higher than in fruit extracts (3.50% and 0.26% per 100 g of extract, respectively). It was shown that extracts of V. vitis-idaea berries and leaves demonstrate high antimicrobial activity against clinical isolates of S. aureus. Further it was established that leaf extracts had high ability to destroy the bacterial biofilm of S. aureus. Leaf extracts were also able to destroy the formed biofilm. Even in the 0.01% concentration, leaf extract inhibited the formation of the biofilm by 69.9% and caused the destruction of the formed biofilm by 62.5%. Thereby, the obtained results show good prospects for the use of V. vitis-idaea leaf extracts as an anti-staphylococcal remedy with antibiofilm forming properties.
Peculiarities of the development and seasonal dynamics of the activity of epigean beetles of the Polyphaga suborder (Coleoptera) in fields of winter wheat in the conditions of Southern Ukraine
Authors: Batschynskaja J. A. , Komisova T. E. , Lykova I. O. 
Published: October 2020

In total, 168 beetle species from 25 families of the suborder Polyphaga have been recorded on winter wheat crops. 116 species (about 20 families) are registered as stratobionts: 14 were dominants, 32 – subdominants and about 70 species were very rare. The main representatives of stratobios were Staphylinidae, Silphidae, Dermestidae, Histeridae, some Elateridae and Scarabaeidae and most Tenebrionidae. Most staphylinids are more numerous in spring (late April – first half of May) and sometimes in summer (especially dominant Tachyporus hypnorum). A high number of Silphidae was noted by mid-May, but decreased in the summer months. Two peaks of abundance are characteristic of Anthicidae, Latridiidae and Cryptophagidae: the smaller in spring (the first half of May) and the maximum in summer (the second half of June – early July). The number of Dermestidae increases gradually from mid-May and reaches maximum from late May to early or mid-June. Among Tenebrionidae, the species of genera Opatrum and Gonocepalum are more numerous in spring than in summer. Crypticus quisquilius were numerous by mid-summer. Among Elateridae, high number of Agriotes sputator was recorded from May to mid-June, and the appearance of Aelosomus rossi was recorded from mid-April, with a peak in the first half of summer. In spring, some Scarabaeidae (some species of Geotrupinae and Pentodon idiota), Histeridae and some species of weevils were more numerous in summer. In years with different meteorological conditions, significant discrepancies were noted in the timing of the rise and fall in the number of many beetles. But smaller differences in the number of specimens are noted between different years in comparision with individual phases of wheat vegetation. Some features of the sex index of beetles (higher during egg laying) and the development of dominant species are briefly considered.