bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-reported COVID-19 symptoms on Twitter: an analysis and a research resource
Authors: Sarker Abeed , Lakamana Sahithi , Hogg-Bremer Whitney , Xie Angel , Al-Garadi Mohammed Ali , Yang Yuan-Chi 
Published: May 2020

AbstractObjectiveTo mine Twitter and quantitatively analyze COVID-19 symptoms self-reported by users, compare symptom distributions across studies, and create a symptom lexicon for future research.Materials and MethodsWe retrieved tweets using COVID-19-related keywords, and performed semiautomatic filtering to curate self-reports of positive-tested users. We extracted COVID-19-related symptoms mentioned by the users, mapped them to standard concept IDs in the Unified Medical Language System, and compared the distributions to those reported in early studies from clinical settings.ResultsWe identified 203 positive-tested users who reported 1002 symptoms using 668 unique expressions. The most frequently-reported symptoms were fever/pyrexia (66.1%), cough (57.9%), body ache/pain (42.7%), fatigue (42.1%), headache (37.4%), and dyspnea (36.3%) amongst users who reported at least 1 symptom. Mild symptoms, such as anosmia (28.7%) and ageusia (28.1%), were frequently reported on Twitter, but not in clinical studies.ConclusionThe spectrum of COVID-19 symptoms identified from Twitter may complement those identified in clinical settings.
Managerial Influence and Organizational Performance
Authors: Rantakari Heikki 
Published: May 2020

ABSTRACT
Agents need to be motivated to develop ideas and to share information regarding their potential value. When the agents fail to agree on which alternative to implement, the principal needs to decide how to resolve the disagreement. When the agents’ information is soft, favoring one of the agents in the case of disagreement is always optimal in the present setting. In contrast, if the information is hard, a balanced treatment of the agents is preferred to encourage competition. The reason for the difference is the high cost of sustaining both informative communication and effort in a balanced organization.
Characteristics of genomic alterations in Chinese cholangiocarcinoma patients
Authors: Jiang Guoping , Zhang Wu , Wang Ting , Ding Songming , Shi Xiaoliang , Zhang Shuirong , Shi Weiwei , Liu Angen , Zheng Shusen 
Published: May 2020

AbstractObjectiveCholangiocarcinoma (CCA) is a primary malignancy, which is often diagnosed as advanced and inoperable due to the lack of effective biomarkers and poor sensitivity of clinical diagnosis. Here, we aimed to identify the genomic profile of CCA and provided molecular evidence for further biomarker development.MethodsThe formalin-fixed paraffin-embedded and matching blood samples were sequenced by deep sequencing targeting 450 cancer genes and genomic alteration analysis was performed. Tumor mutational burden (TMB) was measured by an algorithm developed in-house. Correlation analysis was performed by Fisher’s exact test.ResultsThe most commonly altered genes in this cohort were TP53 (41.27%, 26/63), KRAS (31.75%, 20/63), ARID1A and IDH1 (15.87%, 10/63, for both), SMAD4 (14.29%, 9/63), FGFR2 and BAP1 (12.70%, 8/63, for both), and CDKN2A (11.11%, 7/63). BAP1 mutations were significantly correlated with the CCA subtype. LRP2 mutations were significantly associated with the younger intrahepatic CCA (iCCA) patients, while BAP1 was associated with iCCA patients aged 55–65 years old. BAP1 and LRP2 mutations were associated with TMB.ConclusionsMost Chinese CCA patients were 50–70 years old. BAP1 and LRP2 mutations were associated with the age of iCCA patients.
The first case report of polymerase proofreading-associated polyposis in POLD1 variant, c.1433G&gt;A p.S478N, in Japan
Authors: Ito Tetsuya , Nomizu Tadashi , Eguchi Hidetaka , Kamae Nao , Dechamethakun Sariya , Akama Yoshinori , Endo Goichi , Sugano Kokichi , Yoshida Teruhiko , Okazaki Yasushi , Ishida Hideyuki 
Published: May 2020

Abstract
Polymerase proofreading-associated polyposis, caused by germline variants in the exonuclease domains of POLD1 and POLE, is a dominantly inherited rare condition characterized by oligo-adenomatous polyposis and increased risk of colorectal cancer, endometrial cancer and brain tumours. We report the first Japanese case of polymerase proofreading-associated polyposis carrying a POLD1 variant. The proband was a Japanese woman who had undergone resections of early colorectal carcinomas repeatedly and a hysterectomy with bilateral oophorectomy for endometrial cancer, all of which were diagnosed within 2 years after the first colectomy at 49 year old. Colonoscopic examinations demonstrated at least 14 non-cancerous polypoid lesions, some of which were histologically confirmed to be adenoma. Multigene panel sequencing identified a missense variant in POLD1 (c.1433G&gt;A). Although her relatives did not undergo genetic testing, her father and paternal grandfather died of brain tumours at 53 and ~30 years of age, respectively.
Tick and Tickborne Pathogen Surveillance as a Public Health Tool in the United States
Authors: Eisen Rebecca J , Paddock Christopher D 
Published: May 2020

AbstractIn recent decades, tickborne disease (TBD) cases and established populations of medically important ticks have been reported over expanding geographic areas, and an increasing number of tickborne bacteria, viruses, and protozoans have been recognized as human pathogens, collectively contributing to an increasing burden of TBDs in the United States. The prevention and diagnosis of TBDs depend greatly on an accurate understanding by the public and healthcare providers of when and where persons are at risk for exposure to human-biting ticks and to the pathogens these ticks transmit. However, national maps showing the distributions of medically important ticks and the presence or prevalence of tickborne pathogens are often incomplete, outdated, or lacking entirely. Similar deficiencies exist regarding geographic variability in host-seeking tick abundance. Efforts to accurately depict acarological risk are hampered by lack of systematic and routine surveillance for medically important ticks and their associated human pathogens. In this review, we: 1) outline the public health importance of tick surveillance; 2) identify gaps in knowledge regarding the distributions and abundance of medically important ticks in the United States and the presence and prevalence of their associated pathogens; 3) describe key objectives for tick surveillance and review methods appropriate for addressing those goals; and 4) assess current capacity and barriers to implementation and sustainability of tick surveillance programs.
Understanding News Coverage of Religious-based Violence: Empirical and Theoretical Insights from Media Representations of Boko Haram in Nigeria
Authors: Demarest Leila , Godefroidt Amélie , Langer Arnim 
Published: May 2020

AbstractRecent studies on conflict and terrorism news coverage have documented an ingroup bias as well as an increasingly negative discourse about Muslims in the wake of Islamist terrorist attacks. Yet, as most of these studies have focused on Western media and settings, the determinants of news media’s religious biases and out-group categorizations remain insufficiently understood. In this article, we draw on interviews with Nigerian media practitioners and a comparison of Boko Haram news coverage in two Nigerian newspapers—one Southern-based/Christian-affiliated and one Northern-based/Muslim-affiliated—to argue that it is crucial to consider a country’s political-religious demography in order to understand the way in which religious-based violence is covered in the news. In this respect, we identify micro-, meso- and macro-level theoretical mechanisms through which a country’s demography can promote domestic news outlets—regardless of their background and readership—to cover conflict in a more balanced, nuanced, and objective way.
Outpatient treatment of imported uncomplicated Plasmodium falciparum malaria: results from a survey among TropNet and GeoSentinel experts for tropical medicine
Authors: Lingscheid Tilman , Kurth Florian , Stegemann Miriam S , Clerinx Jan , Calleri Guido , Rothe Camilla , Angheben Andrea , Gobbi Federico , Bisoffi Zeno , Hamer Davidson H , Libman Michael , Hatz Christoph , Zoller Thomas 
Published: May 2020

Abstract

Background
Plasmodium falciparum malaria (P.f. malaria) is frequently imported to non-endemic countries. Recommendations on outpatient treatment differ largely due to differences in country-level guidelines and even between tropical medicine referral centres within the same country.

Methods
This survey among experts from TropNet or GeoSentinel referral centres for tropical medicine outside malaria endemic areas investigated common practices in P.f. malaria management, selection criteria for outpatient management and diagnostic procedures as a first step for developing a future common and evidence-based approach.

Results
A total of 44 referral centres participated. Most of the centres are located in Europe (n = 37). Overall, 27 centres (61%) treat uncomplicated P.f. malaria patients as outpatients, of which eight centres (18%) reported treating ≥75% of patients on an outpatient basis. Seventeen centres (39%) reported treating patients only as inpatients. No single criterion stands out for the decision regarding outpatient treatment, but three groups of factors were identified: (i) clinical criteria including laboratory parameters, clinical condition and tolerance of oral medication; (ii) factors such as patient compliance, reachability by phone and support at home and (iii) patient origin and place of residence as a proxy for possible underlying semi-immunity. The threshold parasitaemia for outpatient treatment varied from 0.1 to 5% with a median of 2%. A median of 0.5% of outpatients were admitted during follow-up. During the last 10 years, 33 complications were reported by nine of the 27 centres and three deaths by one centre.

Conclusion
This study gives insight into the heterogeneous management of P.f. malaria patients outside endemic regions. Although there is no consensus among experts, the majority of centres includes outpatient treatment in their clinical routine. However, the lack of evidence-based criteria and established safety for this approach shows the need for prospective studies to define and evaluate criteria and practices for safe outpatient management.
Detailed chemical compositions of planet-hosting stars – I. Exploration of possible planet signatures
Authors: Liu F , Yong D , Asplund M , Wang H S , Spina L , Acuña L , Meléndez J , Ramírez I 
Published: May 2020

ABSTRACT
We present a line-by-line differential analysis of a sample of 16 planet-hosting stars and 68 comparison stars using high-resolution, high signal-to-noise ratio spectra gathered using Keck. We obtained accurate stellar parameters and high-precision relative chemical abundances with average uncertainties in Teff, log g, [Fe/H], and [X/H] of 15 K, 0.034 cm s−2 , 0.012 dex, and 0.025 dex, respectively. For each planet host, we identify a set of comparison stars and examine the abundance differences (corrected for Galactic chemical evolution effect) as a function of the dust condensation temperature, Tcond, of the individual elements. While we confirm that the Sun exhibits a negative trend between abundance and Tcond, we also confirm that the remaining planet hosts exhibit a variety of abundance–Tcond trends with no clear dependence upon age, metallicity, or Teff. The diversity in the chemical compositions of planet-hosting stars relative to their comparison stars could reflect the range of possible planet-induced effects present in these planet hosts, from the sequestration of rocky material (refractory poor) to the possible ingestion of planets (refractory rich). Other possible explanations include differences in the time-scale, efficiency and degree of planet formation, or inhomogeneous chemical evolution. Although we do not find an unambiguous chemical signature of planet formation among our sample, the high-precision chemical abundances of the host stars are essential for constraining the composition and structure of their exoplanets.
Dark matter distribution in superthin galaxies
Authors: Kalashnikov Ilia 
Published: May 2020

ABSTRACT
This paper presents a new method of calculating dark matter density profiles for superthin axial symmetric galaxies without a bulge. This method is based on a simple physical model, which includes an infinitely thin galactic disc immersed in a spherically symmetric halo of dark matter. To obtain the desired distribution density, it suffices to know a distribution of visible matter surface density in a galaxy and a dependence of angular velocity on the radius. As a byproduct, the well-known expression, which reproduces surface density of a superthin galaxy expressed through a rotation law, was obtained.
On the slow quenching of ℳ* galaxies: heavily obscured AGNs clarify the picture
Authors: Moutard Thibaud , Malavasi Nicola , Sawicki Marcin , Arnouts Stéphane , Tripathi Shruti 
Published: May 2020

ABSTRACT
We investigate the connection between X-ray and radio-loud active galactic nuclei (AGNs) and the physical properties of their evolved and massive host galaxies, focussing on the mass-related quenching channel followed by $\mathcal {M}^\star (\simeq 10^{10.6} \, \mathrm{M}_\odot)$ galaxies in the rest-frame NUV–r versus r–K (NUVrK) colour diagram at 0.2 &lt; z &lt; 0.5. While our results confirm that (1) radio-loud AGNs are predominantly hosted by already-quenched and very massive ($M_*\gt 10^{11}\, \mathrm{M}_\odot$) galaxies, ruling out their feedback as a primary driver of $\mathcal {M}^\star$ galaxy quenching, we found that (2) X-ray AGNs affected by heavy obscuration of their soft X-ray emission are mostly hosted by $\mathcal {M}^\star$ galaxies that are in the process of quenching. This is consistent with a quenching scenario that involves mergers of (gas-poor) $\mathcal {M}^\star$ galaxies after the onset of the quenching process, i.e. a scenario where $\mathcal {M}^\star$ galaxy mergers are not the cause but rather an aftermath of the quenching mechanism(s). In that respect, we discuss how our results may support a picture where the slow quenching of $\mathcal {M}^\star$ galaxies happens due to halo–halo mergers along cosmic filaments.
Exploring formation scenarios for the exomoon candidate Kepler 1625b I
Authors: Moraes R A , Vieira Neto E 
Published: May 2020

ABSTRACT
If confirmed, the Neptune-size exomoon candidate in the Kepler 1625 system will be the first natural satellite outside our Solar system. Its characteristics are nothing alike we know for a satellite. Kepler 1625b I is expected to be as massive as Neptune and to orbit at 40 planetary radii around a ten Jupiter mass planet. Because of its mass and wide orbit, this satellite was first thought to be captured instead of formed in situ. In this work, we investigated the possibility of an in situ formation of this exomoon candidate. To do so, we performed N-body simulations to reproduce the late phases of satellite formation and use a massive circumplanetary disc to explain the mass of this satellite. Our setups started soon after the gaseous nebula dissipation, when the satellite embryos are already formed. Also for selected exomoon systems, we take into account a post-formation tidal evolution. We found that in situ formation is viable to explain the origin of Kepler 1625b I, even when different values for the star–planet separation are considered. We show that for different star–planet separations the minimum amount of solids needed in the circumplanetary disc to form such a satellite varies, the wider is this separation more material is needed. In our simulations of satellite formation, many satellites were formed close to the planet, this scenario changed after the tidal evolution of the systems. We concluded that if the Kepler1625 b satellite system was formed in situ, tidal evolution was an important mechanism to sculpt its final architecture.
Exploring the dispersion measure of the Milky Way halo
Authors: Keating Laura C , Pen Ue-Li 
Published: May 2020

Abstract
Fast radio bursts offer the opportunity to place new constraints on the mass and density profile of hot and ionized gas in galactic haloes. We test here the X-ray emission and dispersion measure predicted by different gas profiles for the halo of the Milky Way. We examine a range of models, including entropy stability conditions and external pressure continuity. We find that incorporating constraints from X-ray observations leads to favouring dispersion measures on the lower end of the range given by these models. We show that the dispersion measure of the Milky Way halo could be less than 10 cm−3 pc in the most extreme model we consider, which is based on constraints from O vii absorption lines. However, the models allowed by the soft X-ray constraints span more than an order of magnitude in dispersion measures. Additional information on the distribution of gas in the Milky Way halo could be obtained from the signature of a dipole in the dispersion measure of fast radio bursts across the sky, but this will be a small effect for most cases.
E. coli Rep helicase and RecA recombinase unwind G4 DNA and are important for resistance to G4-stabilizing ligands
Authors: Paul Tapas , Voter Andrew F , Cueny Rachel R , Gavrilov Momčilo , Ha Taekjip , Keck James L , Myong Sua 
Published: May 2020

AbstractG-quadruplex (G4) DNA structures can form physical barriers within the genome that must be unwound to ensure cellular genomic integrity. Here, we report unanticipated roles for the Escherichia coli Rep helicase and RecA recombinase in tolerating toxicity induced by G4-stabilizing ligands in vivo. We demonstrate that Rep and Rep-X (an enhanced version of Rep) display G4 unwinding activities in vitro that are significantly higher than the closely related UvrD helicase. G4 unwinding mediated by Rep involves repetitive cycles of G4 unfolding and refolding fueled by ATP hydrolysis. Rep-X and Rep also dislodge G4-stabilizing ligands, in agreement with our in vivo G4-ligand sensitivity result. We further demonstrate that RecA filaments disrupt G4 structures and remove G4 ligands in vitro, consistent with its role in countering cellular toxicity of G4-stabilizing ligands. Together, our study reveals novel genome caretaking functions for Rep and RecA in resolving deleterious G4 structures.
Butterfly wing architectures inspire sensor and energy applications
Authors: Osotsi Maurice I , Zhang Wang , Zada Imran , Gu Jiajun , Liu Qinglei , Zhang Di 
Published: May 2020

Abstract
Natural biological systems are constantly developing efficient mechanisms to counter adverse effects of increasing human population and depleting energy resources. Their intelligent mechanisms are characterized by the ability to detect changes in the environment, store and evaluate information, and respond to external stimuli. Bio-inspired replication into man-made functional materials guarantees enhancement of characteristics and performance. Specifically, butterfly architectures have inspired the fabrication of sensor and energy materials by replicating their unique micro/nanostructures, light-trapping mechanisms and selective responses to external stimuli. These bio-inspired sensor and energy materials have shown improved performance in harnessing renewable energy, environmental remediation and health monitoring. Therefore, this review highlights recent progress reported on the classification of butterfly wing scale architectures and explores several bio-inspired sensor and energy applications.
Pal Joey Goes to Hollywood
Authors: Lindberg Julianne 
Published: May 2020

Abstract
The 1957 screen adaptation of Pal Joey—starring Frank Sinatra as Joey, Rita Hayworth as Vera, and Kim Novak as Linda—redeems Joey. Now a singer rather than a dancer, Joey genuinely falls in love with Linda. In the end Joey gets the girl. The film promotes a set of emerging gender archetypes that defy middle-class, suburban constructions of masculinity and femininity. Joey’s stage-to-screen evolution—from heel to swinging bachelor—is mirrored by Linda’s transformation from stenographer to sex kitten. Both of these archetypes are responses to what cultural theorists have called the postwar “crisis” in masculinity. The character Vera too is altered. As played by Rita Hayworth, she is tamed by Joey. The anxiety over contested gender roles is reflected in the alteration of the original score, which is reworked, repurposed, and in some cases eviscerated in order to promote the ethos of the film.
Biblical Miniseries in the 2010s
Authors: Howell Charlotte E. 
Published: May 2020

Abstract
Produced by Mark Burnett and Roma Downey, The Bible (History, 2013), A.D.: The Bible Continues (NBC, 2015) and The Dovekeepers (CBS, 2015) operate as extensions of the Touched by an Angel approach to religious serial dramas. Ironically, success was achieved on a cable scale but not broadcast scale, despite the majority of Americans still identifying as Christian, indicating that the mass audience for dramas won’t be found in the Christian-tinged middlebrow appeal that helped shows like Touched by an Angel succeed in the 1990s. Thus, these overtly Christian series that are framed and marketed as Christian illustrate the decline in the value of that audience to the television industry in the current fractured market.
The Theological Origins of White Supremacy
Authors: Norris Kristopher 
Published: May 2020

Abstract
Chapter 2 offers a historical and theological account of the theological elements that contributed to the development of white supremacy. It highlights crucial historical moments in the emergence of white supremacy and demonstrates the way white, European theology created and sustained its dominance. The chapter then analyzes the continuing malformative aspects of white Christian theology. To demonstrate that all of white theology is contaminated with racism, it investigates the ways elements of white supremacy show up in the work of two of America’s most influential theologians, Walter Rauschenbusch and Reinhold Niebuhr. The text demonstrates the theological origins of white supremacy and identifies its continuing presence in corrupting even the most well-intentioned white theology.
Narrating Black Theology
Authors: Norris Kristopher 
Published: May 2020

Abstract
Employing the theology of James Cone as a representative of black liberation theology, this chapter analyzes the narrative basis of his ecclesiology as a vision of the church untethered from whiteness. The analysis demonstrates the ways Cone’s ecclesiology contrasts and refines Hauerwas’s. It attends specifically to the ways his narrative theology offers more promising resources for rightly telling the story of white Christianity and offering better witness to our whiteness. This chapter identifies the three conceptual elements of an ethic of responsibility in his thought—memory, particularity, and concreteness. Then, drawing on womanist engagement with his work, argues that Cone offers the concept of “narrative blackness” that invites white theologians and Christians to a form of conversion he calls “becoming black.”