bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solidarity
Authors: Syvertsen Jennifer 
Published: February 2025

AbstractWhat if as researchers we do not share the same experiences or belong to the same structurally marginalized communities with whom we work, yet we recognize an urgent collective need to address health injustices? In this essay, I reflect on what it means for academic researchers to work in solidarity with communities. Drawing on my community‐based research on opioid overdose and harm reduction, I think about solidarity as a form of pedagogy that does not rely on notions of similarity, but rather recognizes the incommensurability of differences as part of an interlinked struggle. This approach to building solidarity is grounded in social relationships, empathy, and reciprocity and calls for collective action. Reflecting on the importance of harm reduction and the relationships we develop with people who use drugs and bear the brunt of politically‐induced suffering is not just an academic exercise, but a possibility for building life‐sustaining solidarity. In the case of the ongoing overdose crisis that has devastated communities, finding new ways to reclaim and enact solidarity is critical if our goal is collective survival.
Care
Authors: Vázquez Evelyn 
Published: February 2025

AbstractThis article critiques “care” within the neoliberal university through two questions: What is the meaning of “care” in a neoliberal university? How is the neoliberal university addressing the social and structural factors that prevent scholars from marginalized communities from succeeding in higher education? It condemns the superficial care promoted by the neoliberal university, which prioritizes competition, prestige, and productivity over genuine support. Participatory‐action research challenges these practices by centering marginalized voices. The study included 10 participants (7 women, 2 men, 1 non‐binary), all low‐income, first‐generation college students. Using PhotoVoice, a participatory‐action research method, participants documented their social connectedness, sense of belonging, and mental health in graduate education. Their narratives revealed neglect and invisibility, highlighting the negative effects of limited resources, precarious working conditions, financial instability, food insecurity, and inadequate housing on their well‐being and quality of life. The article argues that neoliberal universities perpetuate neglect and avoid addressing structural issues like structural racism and settler colonialism. It proposes self‐reflexivity, intentionality, and collective resistance as transformative care practices essential for dismantling oppressive systems. These practices offer a revolutionary approach to resisting neoliberalism and fostering community‐based care, healing the symbolic, psychological, and emotional harm caused by neoliberal policies. Transformative care is crucial to foster health equity and collective healing in higher education.
Knowledge and Perceptions of Supplemental Nutrition Assistance Program‐Eligible Purchases: A Survey of US Midwestern College Students
Authors: Chrisman Matthew , Landry Matthew J. , Klobodu Seth , Bailey Dylan 
Published: February 2025

ABSTRACTLittle is known regarding the intrastudent barriers to accessing and utilising the Supplemental Nutrition Assistance Program (SNAP). To examine college students' knowledge of allowable items and perception of what items should be allowed for purchase with (SNAP) benefits, particularly by food security status and enrolment in SNAP in the past 12 months, a cross‐sectional, online survey was conducted among 844 college students from nine higher education institutions in a single Midwestern state. Many students were unaware that certain food items were already covered by SNAP, leading them to express a desire for these items to be included. Additionally, there were misconceptions about the eligibility of nonfood items for purchase using SNAP benefits. Beyond traditional food items, students highly desired the inclusion of necessities such as toiletries and cooking equipment. Improved outreach and educational campaigns could be developed to clarify the eligible items and scope of the programme, enabling students to make informed decisions about their SNAP benefit usage.
Optimized LED phototherapy induces ROS‐mediated membrane damage in Trichophyton rubrum for effective onychomycosis treatment
Authors: Li Angze , Ren Yi , Peng Zhenjian , Liu Shangfeng , Liu Muqing 
Published: February 2025

AbstractOnychomycosis, predominantly induced by Trichophyton rubrum, is a pervasive nail disorder within dermatology known for its high relapse rates and suboptimal patient adherence to treatment regimens. While photomedicine has emerged as a promising therapeutic modality, efficiency reductions are common due to deck obstruction in conventional light therapy. The spectral flexibility of LEDs offers a compelling solution, allowing for deeper deck penetration while maintaining efficacy. We have developed an advanced LED system with optimized optical parameters and have elucidated the antimicrobial mechanisms underlying this technology. Our research shows that an optimal wavelength of 405 nm, an energy density of 396 J/cm2, and an average light intensity of 140 mW/cm2 demonstrate superior efficacy in treating onychomycosis. The antifungal mechanism of our pulsed LED system involves the induction of reactive oxygen species (ROS) within fungal mycelia, ultimately resulting in membrane damage. These insights highlight the potential of LED lighting systems as a novel antimicrobial strategy, offering a promising avenue for the treatment of onychomycosis.
All you'll feel is doom and gloom: Multiple perspectives on the associations between economic anxiety and conspiracy beliefs
Authors: Adamus Magdalena , Chayinska Maria , Šrol Jakub , Adam‐Troian Jais , Ballová Mikušková Eva , Teličak Peter 
Published: February 2025

AbstractThe article investigates whether and how adherence to conspiracy beliefs (CBs) about COVID‐19 pandemic might be associated with (and cause) economic anxiety over various cultural settings and time. First, we examined the extent to which CBs predicted economic anxiety using the European Social Survey data, round 10, from 17 countries (Study 1). Second, using data from a balanced (in terms of age, gender, education, and region) Slovak sample, we employed a cross‐lagged panel analysis to determine the direction of the association between adherence to CBs and economic anxiety (Study 2). Study 1 revealed that adherence to CBs was significantly associated with higher levels of economic anxiety across cultural contexts. Study 2 compellingly showed that adherence to CBs increased the sense of economic anxiety over time, whereas the reverse causal path from economic anxiety to CBs was consistently nonsignificant. This work provides evidence that adherence to CBs may be increasingly associated with adverse subjective appraisals of economic realities. We discuss how our results can contribute to the understanding that curbing adherence to CBs could also alleviate the sense of economic anxiety. Finally, we recommend a research agenda to better understand the psychological boundary mechanisms accounting for these effects.
Wild soybean cotyledons at the emergence stage tolerate alkali stress by maintaining carbon and nitrogen metabolism, and accumulating organic acids
Authors: Sun Yang , Shu Hang , Lu Duo , Zhang Tao , Li Mingxia , Guo Jixun , Shi Lianxuan 
Published: February 2025

AbstractSoil alkalization is a global ecological problem that constrains food security and sustainable socio‐economic development. As a wild relative of soybean, wild soybean (Glycine soja) exhibits strong salt and alkali stress resistance and its cotyledons play a key role during the emergence (VE) stage. This study aimed to compare variations in growth parameters, cotyledon ultrastructure, photosynthetic physiology, mineral ion and metabolite contents, and gene expression in two ecotypes of wild soybean to elucidate the regulatory mechanisms underlying alkali stress resistance in salt‐tolerant wild soybean cotyledons during the VE stage. The results showed that salt‐tolerant wild soybean cotyledons exhibited relatively stable growth parameters, dense and orderly chloroplast structure, high photosynthetic rates, as well as high K+ and Ca2+ contents under alkali stress. Metabolomics, transcriptomics, and weighted gene co‐expression network analyses revealed that salt‐tolerant wild soybean cotyledons adapted to alkali stress during the VE stage by enhancing photosynthetic carbon assimilation pathways, increasing methionine and proline biosynthesis, and enhancing gamma‐aminobutyric acid biosynthesis, thereby maintaining a stable carbon and nitrogen balance. In addition, upregulation of the expression of ICL, MS, and ACO2 led to the accumulation of various organic acids, such as pyruvic, aconitic, succinic, oxalic, malic, and fumaric acids, thereby promoting the synthesis of organic acid metabolism modules. This study provides novel insights into the key metabolic modules by which wild soybeans resist alkali stress.
Methionine adenosyltransferase MAT3 positively regulates pear pollen tube growth, possibly through interaction with pectin lyase‐like protein PLL1
Authors: Zhu Xiaoxuan , Zhang Ting , Tang Chao , Wang Zhiqi , Guo Lin , Wang Peng , Zhang Shaoling , Wu Juyou 
Published: February 2025

AbstractMethionine adenosyltransferase (MAT) is the only enzyme that synthesises S‐adenosylmethionine (SAM) from ATP and methionine in organisms. While MAT has been extensively studied in plant development and responses to abiotic stress, its role in plant fertilization, particularly in pear pollen tube growth, has been scarcely researched. Here, we demonstrate that the homologous gene of AtMAT3 in pear, PbrMAT3, is positively involved in pear pollen tube elongation. PbrMAT3 is predominantly expressed in pear pollen. Transient knockdown of PbrMAT3 inhibits pollen tube growth. Ethionine, a toxic methionine analogue, suppressed pollen tube growth in control samples but had no inhibitory effect on PbrMAT3‐knockdown pollen tubes, suggesting increased methionine accumulation in the latter. However, this accumulation is not responsible for the observed growth inhibition. PbrMAT3 interacts with a pectin lyase‐like protein, PbrPLL1, both in vivo and in vitro. Transient knockdown of PbrPLL1 promotes pollen tube growth, suggesting its negative role in pear pollen tube elongation. Additionally, the pectate lyase activity of the pear pollen tube was increased when PbrMAT3 was knocked down. Thus, the inhibition of pollen tube growth due to PbrMAT3 knockdown is not caused by methionine accumulation but may be mediated by PbrPLL1. This study provides new insight into the relationship between S‐adenosylmethionine synthesis and pollen tube growth.
Comprehensive Profiling of Computational Techniques for Sequencing‐Based HLA Immune Signatures Extraction
Authors: Jiang Limin , Baker Steven F. , Ceccarelil Michele , Guo Yan 
Published: February 2025

ABSTRACTHLA typing is crucial for clinical and research applications, including transplantation, disease association studies and personalised medicine. This study provides an in‐depth analysis of five key challenges in computational HLA typing methods: varying lengths, high polymorphism, complex phylogenetic structures, high sequence similarity and the requirement for frequent updates. This study evaluates 27 computation‐based HLA typing tools developed over the past 12 years, using a novel sequencing dataset of A549 cell lines with matched short‐read RNA‐Seq and long‐read Iso‐Seq data. We comprehensively investigated these 27 tools in terms of accessibility, capability, reliability, reproducibility, scalability and performance. In addition, we discuss the advantages and disadvantages of current tools and identify critical areas for future research and development to advance HLA typing technologies.
Characterisation of the Novel HLA‐A*01:471 Allele by Sequencing‐Based Typing
Authors: Pajot Thibault , Elsermans Vincent , Top Isabelle , Labalette Myriam 
Published: February 2025

ABSTRACTHLA‐A*01:471 differs from HLA‐A*01:01:01:01 by one nucleotide substitution in codon 250 in exon 4.
The Role of AI in Reshaping Medical Education: Opportunities and Challenges
Authors: Ali Majid 
Published: February 2025

ABSTRACTArtificial intelligence (AI) is redefining medical education, bringing new dimensions of personalized learning, enhanced visualization and simulation‐based clinical training to the forefront. Additionally, AI‐powered simulations offer realistic, immersive training opportunities, preparing students for complex clinical situations and fostering interprofessional collaboration skills essential for modern healthcare. However, the integration of AI into medical education presents challenges, particularly around ethical considerations, skill atrophy due to overreliance and the exacerbation of the digital divide among educational institutions. Addressing these challenges demands a balanced approach that includes blended learning models, digital literacy and faculty development to ensure AI serves as a supplement to, rather than a replacement for, core medical competencies. As medical education evolves alongside AI, institutions must prioritize strategies that preserve human‐centred skills while advancing technological innovation to prepare future healthcare professionals for an AI‐enhanced landscape.
Combinatorial Decellularization as a Better Approach to Porcine Liver Extracellular Matrix Scaffold Fabrication With Preserved Bioactivity: A Comparative Evaluation
Authors: Puthiya Veettil Jesna , Sasikumar Lolitha Devika , Payanam Ramachandra Umashankar 
Published: February 2025

ABSTRACTSoft tissue repair patches of decellularized extracellular matrices (ECM) with inherently preserved structural components and biomacromolecules are desirable in regenerative applications. This study characterizes three detergent‐based decellularization methods to fabricate acellular porcine liver matrices to remove antigenic determinants without compromising the structural integrity, glycosaminoglycans (GAG) content, and bound growth factors within the resulting ECM. Three detergents chosen for decellularization were sodium dodecyl sulfate (SDS), SDS with sodium deoxycholate (SDS + SDC‐combinatorial method), and Triton X‐100 followed by SDS. Combinatorial detergent decellularization effectively removed cellular components and retained intact collagenous structure with minimal residual DNA and protein. It also preserved significantly higher amounts of GAG, HGF, and bFGF. TX100 decellularization was highly destructive with the least preservation of GAG and GFs. The SDS method showed an intermediate level of preservation of biomolecules. The correlation obtained between GAG and GFs revealed quantification of GAG to be an indirect way of estimating the bound GFs preserved within the ECM. In vitro experiments revealed the noncytotoxic nature of the scaffolds. The study revealed that, among the three methods of decellularization, ECM scaffold fabricated by combinatorial detergent decellularization is extremely promising for use as a soft tissue repair patch with inherent bioactive molecules for scaffold‐based regenerative therapy.
Combustion Characteristics of Premixed Ammonia/Methane/Air blends as an Alternative Fuel in a Swirl-Stabilized Gas Turbine Can Combustor Sustained Using a Pilot Flame
Authors: Das Chaudhury Meghna , Sahoo Abinash , Ekkad Srinath V. , Narayanaswamy Venkateswaran 
Published: February 2025

Abstract
The present research work investigated the combustion characteristics of lean premixed Ammonia/Methane/Air flames in an atmospheric pressure swirl-stabilized gas turbine can combustor. The study focused on characteristics such as flame structure, flame stability, combustor liner wall heat load and emissions. Different volume % of Ammonia-Methane (0-50 % Ammonia, rest being Methane) blends were considered at an equivalence ratio = 0.6 and at Reynolds number ∼ 50000 where the flame was sustained using a 10 % Methane pilot flame. High-speed flame luminosity imaging was carried out to study the flame structure and flame stability. Infrared thermography was used to simultaneously measure both outer/inner wall temperatures and to estimate the liner wall heat load. For studying emissions, steady-state numerical modeling was carried out using the CONVERGE CFD 3.0 software where both isothermal and adiabatic cases were studied. The latter comprised the entire volume fraction of Ammonia and Methane. Particle Image Velocimetry data were used to validate the numerical model. In the study, Ammonia/Methane/Air flames were found to exhibit increased flame-turbulence interaction compared to the pure Methane-Air flame. Flame instability and flame extinction were observed in the 50 % Ammonia-50 % Methane flame in the downstream section of the combustor away from the pilot flame and along the combustor wall. Compared to the combustor wall heat in the pure Methane-Air flame, in Ammonia/Methane flames, combustor wall heat load was found to be reduced by ∼ 10 to 40 % for various cases. In addition, NOx emissions were found to be less under isothermal condition as compared to adiabatic condition because of unburnt fuel.
Solar Simulator Prototype With Halogen and LED Sources
Authors: da Cruz Gustavo P.C. , Barreto Gabriel Lima , Gómez-Malagón Luis A , Lima Ricardo , Vital Caio 
Published: February 2025

Abstract
Hybrid Solar Simulators (SS) using halogen lamps and LEDs, classified as A for spectral match and temporal instability, are primarily reported for characterizing small solar cells (∼160 cm2). However, spatial nonuniformity reports are rare. This manuscript presents the characterization of a large-area hybrid SS capable of simulating sunlight intensity and spectrum using a combination of 10 white LEDs, 6 halogen lamps, and power LEDs emitting at 450 nm (blue), 750 nm (magenta), and 850 nm (infrared). This setup ensures homogeneous light distribution over a 600 cm2 surface. The proposed SS was characterized according to the IEC 60904-9 standard, analyzing Spectral Match (SM), Spatial Non-Uniformity (SNU), and Temporal Instability (TI). The obtained values (SM = 1.29, SNU = 1.5%, and TI = 0.17%) classify the simulator as BAA. Electrical characterization of a 5W solar panel (300 cm2) was performed via current-voltage (I–V) and power-voltage (P–V) curves under indoor and outdoor conditions. A relative error of less than 4% was found compared to outdoor measurements, making it suitable for photovoltaic device testing. The results demonstrate the feasibility of developing a low-cost SS using incandescent and semiconductor light sources, with potential for characterizing commercial photovoltaic devices.
Innovative Advances in EV-Driveline Lubrication: Optimizing Lubricants for Enhanced Efficiency and Sustainability
Authors: Naundorf Tim , Butcher Richard , Hellwig Thomas , Seman Gregory , Knoblauch Daniel 
Published: February 2025

Abstract
The global reduction of CO2 emissions, including from the transportation sector, is critical for addressing climate change. New electric vehicles (NEVs) are pivotal in this effort, with battery electric vehicles (BEVs) being a primary focus, due to their potential for significantly reducing emissions. This study investigates the efficiency of selected lubricants in the context of an electric axle (E-axle) drivetrain, a key component in BEVs. Compared with conventional vehicles, driveline efficiency may be viewed as even more essential for the BEV. Here all aspects of efficiency are essential to improve delivery from the main drive battery capacity, reduce vehicle weight, and improve overall performance. By testing different fluids and formulations, this research identifies significant efficiency gains from the E-axle, which directly contribute to enhancing the range, whilst reducing the operational costs. Using a typical E-axle, the study practically demonstrates that the targeted selection and optimization of lubricant can achieve worthwhile efficiency improvements. It is expected that efficiency gains are possible with other motors and drivetrains. However, each system requires individual optimization to realize such benefits. This research demonstrates the importance of customizing lubricant solutions to the specific demands of each drivetrain, thereby supporting the broader adoption of more efficient and sustainable electric vehicle technologies.
Inhaled methoxyflurane (Penthrox) use in the outpatient and ambulatory setting: a systematic review
Authors: Sairally Bibi Zeyah Fatemah , De Silva Prathiba M , Smith Paul , Clark T Justin 
Published: February 2025

ObjectiveWe assessed whether Penthrox (methoxyflurane) can provide better pain relief for elective, outpatient interventional procedures compared with other methods of pain control.DesignSystematic review.Data sourcesCochrane Central Register of Controlled Trial, MEDLINE, Emcare, Embase, ClinicalTrials.gov and the Cumulative Index to Nursing and Allied Health Literature were searched from inception to 6 November 2023.Eligibility criteriaAll published studies including randomised controlled trials (RCTs), cohort studies and case–control studies investigating Penthrox for pain relief, during and/or after an interventional procedure, were included.Data extraction and synthesisTwo independent reviewers identified eligible studies and retrieved data. Risk of bias was assessed using Cochrane Collaboration Risk of Bias V.2.0 and Risk of Bias in Non-randomised Studies of Interventions (ROBINS I) tools. A meta-analysis was not possible due to heterogeneity.ResultsThe literature search yielded 1189 records. 12 studies were eligible for inclusion: 5 RCTs and seven non-randomised studies of interventions (NRSIs). Penthrox was used for a range of procedures across five medical specialities: gastroenterology, gynaecology, haematology, orthopaedics and urology. Two RCTs showed a significant reduction in intraprocedural pain when Penthrox was compared with placebo. However, three RCTs where Penthrox was compared with either placebo or intravenous sedation showed no significant differences in pain or comfort level. Similarly, the NRSIs showed variable results. Most patients were satisfied (63% to >98%; seven studies) with Penthrox, and seven out of eight studies reported that the majority of participants would use it again (46.8%–95%; eight studies). No serious adverse events were reported.ConclusionPenthrox (methoxyflurane) shows promise as an analgesic for invasive, elective interventional procedures in the outpatient setting, although the relative benefits appear to vary depending on intervention and comparator pain control measures. There is a pressing need for robustly conducted, large, generalisable multicentre RCTs to evaluate the effectiveness of Penthrox.PROSPERO registration numberCRD42023404574.