bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards an activist research: Is Wikipedia the problem or the solution?
Authors: Duncan Alexandra 
Published: November 2020

ABSTRACTIs the internet a tool for democracy or the manifestation of the global digital divide? Using the colonization of the internet as a starting point, this article outlines some current issues with knowledge equity, asking if democratic open access products like Wikipedia are the solution or another manifestation of the systemic bias of society. Whilst acknowledging librarianship has its own colonial legacies to address, the suggestion is made that critical librarianship can provide a response in the form of library–based edit-a-thons and Wikipedia workshops. These show how the power of Wikipedia can be used responsibly not just for enabling critical information literacy, but as an instrument for activism. In considering librarian interventions done so far at the University of the Arts, London, the article outlines future practical possibilities for decolonization, as well as looking more widely at how to democratize information in open access products and the Western publishing that sits behind them.
Understanding the Nature and Context of Domestic Homicide Committed by Female Victims of Domestic Violence in Iran: Examining Current and Alternative Criminal Justice Responses
Authors: Amini Mahbube 
Published: November 2020

AbstractDomestic homicide is the most serious type of violence in a marital relationship, which is punishable by the death penalty as retaliation (Qisas) according to the Penal Code of Iran. The present paper analyzes why a woman commits this crime (the killing of her husband), examining the killer’s status in a marital relationship. Data show that the killers had been victims of domestic violence for 10–25 years. In other words, domestic homicide has a direct relationship with the killer being victimized by domestic violence, including physical (assault and battery), mental (insult and obscenity), sexual and sometimes financial violence that may result from addiction. The most important reason for domestic homicide is the failure to provide legal and social protection for women. This incites hatred for the husband, which arises from repeated victimization in a coercive relationship with the husband. These women cannot end this coercive relationship because of insufficient or unavailable legal, social or family protection. Moreover, the process of divorce for a woman in Iran is quite complex. This article also examines the potential defense of mental capacity and self-defense and its place in the Iranian penal code. Based on this research, this article argues for the need for the legislature to review the death penalty for this kind of crime and to consider other possible responses to such murders.
Resistance Trends in Pathogens Causing Healthcare-Associated Infections in Multiple Hospitals in Saudi Arabia, 2007–2016
Authors: Alshamrani Majid , Ramadan Aiman , Alsaedi Asim , Nasser wafa Al , Gammal Ayman El , Aljohani Sameera , Almunif Sara , Arabi Yassen , Alqahtani Saad , Baffoe-Bonnie Henry , Alghoribi Majed , Alothman Adel , Yaseen Muhammad , AlMohrij Saad 
Published: November 2020

Background: Studying temporal changes in resistant pathogens causing healthcare-associated infections (HAIs) is crucial in improving local antimicrobial and infection control practices. We analyzed 10-year trends in resistance in pathogens causing HAIs in a tertiary-care setting in Saudi Arabia and we compared such trends with those of the US NHSN. Methods: We performed a pooled analysis of surveillance data that were prospectively collected between 2007 and 2016 in 4 hospitals of the Ministry of National Guard Health Affairs. Definitions and methodology of HAIs and antimicrobial resistance were based on NHSN methods. Consecutive NHSN reports were used for comparisons. Results: In total, 1,544 pathogens causing 1,531 HAI events were included. Gram-negative pathogens (GNPs) were responsible for 63% of HAIs, with a significant increasing trend in Klebsiella spp and a decreasing trend in Acinetobacter spp. Methicillin-resistant Staphylococcus aureus (27.0%) was consistently less frequent than NHSN reports. Vancomycin-resistant Enterococci (20.3%) more than doubled during the study, closing the gap with the NHSN. Carbapenem resistance was highest for Acinetobacter (68.3%) and Pseudomonas (36.8%). Increasing trends of carbapenem resistance were highest for Pseudomonas and Enterobacteriaceae, closing the initial gaps with the NHSN. With the exception of Klebsiella and Enterobacter, multidrug-resistant (MDR) GNPs generally decreased, mainly due to the decreasing resistance to cephalosporins, fluoroquinolones, and aminoglycosides. Conclusions:The current trends probably reflect multiple local interventions to reduce HAIs and MDR as well as the heavy use of carbapenems and vancomycin. Our main challenge remains to further enhance the newly launched antimicrobial stewardship practices.Funding: NoneDisclosures: None
Site Visits Reveal Common Gaps in Instrument Reprocessing and Sterilization at Philadelphia Dental Clinics
Authors: Peritz Tiina , Coffin Susan 
Published: November 2020

Background: Most dental clinics lack resources and oversight related to infection prevention and control (IPC) practices. Few dental clinics undergo inspections by regulatory authorities unless the state licensing authorities receive a specific complaint. Many states, including Pennsylvania, do not have continuing IPC education requirements for dental providers. In 2018–2019, the Philadelphia Department of Public Health (PDPH) received and responded to multiple complaints and concerns related to IPC practices at dental clinics. Complaints were investigated in collaboration with the Pennsylvania Department of State (PADOS). Methods: Unannounced site visits were conducted at 7 Philadelphia dental clinics from December 2018 through September 2019 as part of the public health responses. Clinic evaluations and observations by PDPH certified infection preventionists focused on (1) IPC policies and procedures, (2) staff IPC training, (3) hand hygiene, (4) personal protective equipment, (5) instrument reprocessing and sterilization, (6) injection safety, and (7) environmental cleaning and disinfection. The CDC and the Organization of Safety, Antisepsis and Prevention (OSAP) checklists were adapted for this purpose. Results: Most dental practices we visited were small, unaffiliated, owner-operated clinics. The most common gaps we identified were associated with instrument reprocessing and sterilization practices, including inadequate separation between clean and dirty work areas, limited space and availability of sinks, inappropriate use of glutaraldehyde products for instrument cleaning (n = 3, 43%), extended reuse of cleaning brushes (n = 5, 71%), sterilization or storage of sterilized instruments without appropriate packaging (n = 2, 29%), lack of spore testing or reviewing results (n = 2, 29%), and lack of documentation of sterilizer run cycles and maintenance (n = 7, 100%). Additionally, most clinics did not have well-developed IPC policies and procedures, and staff IPC trainings were neither documented nor conducted annually. Alcohol-based hand sanitizer was often not available at the point of use. Conclusions: In Philadelphia, dental clinics often lacked IPC support and oversight. Lapses across multiple key IPC domains were common. These findings suggest that public health may have a role in providing IPC support to unaffiliated dental clinics. Licensing entities can also serve a role in improving IPC practices by more widely mandating continuing IPC education as part of the dental license renewal process.Funding: NoneDisclosures: None
Standardized Antimicrobial Administration Ratio (SAAR) Clinical Outcomes Assessment in a Large Community Healthcare System
Authors: Burgess Hayley , Cooper Mandelin , Goldin Laurel , Sands Kenneth 
Published: November 2020

Background: Research on the association between the standardized antimicrobial administration ratio (SAAR) and clinical outcomes is lacking. Objective: We compared SAAR and patient outcomes in 97 acute-care facilities affiliated with a large healthcare system. Methods: Facilities were classified using the broad-spectrum hospital-onset (BSHO) SAAR for medical, surgical, and medical-surgical wards as low, moderate, or high antimicrobial use: low use SAAR, <0.8; moderate use SAAR, 0.95–1.05; and high-use SAAR, >1.2. Data were included from patients aged ≥18 years who were discharged between the first quarter of 2018 and the second quarter of 2019, had nonmissing matching criteria, BMI between 10 and 90, and at least 1 BSHO medication administered in a medical, surgical, or medical-surgical ward. Patients were matched for gender, age group, BMI category, year and quarter of discharge, ICU stay, and diagnosis-related group (DRG). Eligible drugs included all routes for cefepime, ceftazidime, doripenem, imipenem/cilastatin, meropenem, and piperacillin/tazobactam and IV only for amikacin, aztreonam, gentamicin, and tobramycin. Outcomes were evaluated in a pairwise manner using t tests or χ2 tests. Results: Each of the 3 study groups consisted of 6,327 patients, 51% of whom were men; average age, 63 years; 70% of whom were obese or overweight, and 19% of whom had an ICU stay. The most common DRG code was infectious and parasitic diseases (57%) followed by digestive system (9%), respiratory system (7%), and kidney and urinary tract (6%). High antibiotic use was associated with longer length of stay and a higher estimated cost per visit. Low antibiotic use was associated with higher rate of mortality and a lower rate of readmissions compared to moderate use. The low-usage group did not exhibit a statistically significant difference in mortality, readmissions, or rate of C. difficile compared to the high-usage group. Conclusions: The optimal antibiotic utilization group varied among outcomes. Further evaluation of outcomes is needed for the SAAR to understand the ranges and the relationship between the measure and clinical outcomes.Funding: NoneDisclosures: None
Staphylococcus spp Resistance to Chlorhexidine: Is There Any Impact Related to the Routine Use for Hand Hygiene?
Authors: Boszczowski Icaro , Minami William Kazumassa , Baraldi Marcia , Marchi Ana Paula , Santos nia Alves dos , schmitt o Paulo cristiane , Maciel Amanda Luiz Pires , Zani Maria Eduarda Rufino , Souza cia Muniz , Souza Nicole Soares de , Costa Silvia Figueiredo 
Published: November 2020

Background: Although guidelines recommend the use of chlorhexidine gluconate (CHG) for hand hygiene (HH), the impact of its routine use on antimicrobial resistance is not clear. Objective: To analyze the impact on the CHG susceptibility among isolates obtained from hands of HCW during its routine use for HH. Methods: We conducted a crossover study at 4 medical-surgical wards of a tertiary-care hospital in São Paulo, Brazil. In 2 units (intervention group), we established routine use of CHG for HH. For the other 2 units (control group), regular soap was provided. The availability of alcohol formulation for HH was not changed during the study. Every 4 months we swapped the units, ie, those using CHG changed for regular soap and vice versa. At baseline, we cultured the hands of HCWs. Only nursing staff hands were investigated. For hand culturing, HCWs placed their hands inside a sterile bag containing a solution of phosphate-buffered saline, Tween 80, and sodium thiosulfate. After the solution incubated overnight, it was inoculated onto brain-heart infusion. Next, it was plated on McConkey and Mannitol agar. MALDI-TOF was used for identification. Agar dilution was performed for Staphylococcus spp. We selected all Staphylococcus spp with MIC ≥ 8 and performed inhibition of efflux pump test. For isolates that showed a decrease of 2 dilutions, we searched the gene qacA/B by polymerase chain reaction. Results: We obtained 262 samples from HCW hands yielding 428 isolates. The most frequent genera were Staphylococcus spp (58%), Acinetobacter spp (8%), Enterobacter spp (8%), Stenotrophomonas spp (5%), Klebsiella spp (4%), Pseudomonas spp (3%), and others (14%). Staphylococcus spp were less frequent in the intervention compared to control group (43% vs 61%; OR, 0.48; 95% CI, 0.29–0.69; P = .005). Among all Staphylococcus spp, the proportion of chlorhexidine resistance (RCHG; MIC ≥ 8) was 12%. All resistant isolates recovered susceptibility after inoculation with pump-efflux inhibitor. For pump-inhibited isolates, 53% had the gene qacA/B amplified by PCR. We did not investigate RCHG among gram-negative isolates. There was a nonsignificant increase in Staphylococcus spp RCHG in the intervention group (4% to 6%; P = .90). Healthcare-acquired infection rates did not change significantly during the intervention. The consumption of CHG increased from 7.3 to 13.9 mL per patient day. Conclusions: We did not detect a significant difference in RCHG during the routine use of CHG for HH, although we observed increasing resistance. Further investigation is needed to clarify other reasons for increasing MIC to CHG.Funding: NoneDisclosures: None
Strategy for Increasing Alcohol Gel Consumption Based on Realistic Simulation, Opinion of Healthcare Workers, Structure Adequacy and Change in Alcohol Product
Authors: Abraao Ligia , Anjos Sandra Nascimento dos , Tonheiro Chayenne Mika Matsumoto Pinto , Lima la Souza , Braz Mariana Sarkis , Pires Sarita , Cais Daiane , Miranda Bianca , Cocentino sar Batista , Paulo o , Paulo o 
Published: November 2020

Background: Healthcare-related infections (HAIs) imply higher morbidity and mortality, length of hospitalization, and costs to institutions and the health system. An important practice for HAI control is hand hygiene. Due to the need for greater adherence to the practice of hand hygiene, as well as understanding about behavior and motivations related to actions associated with infection control, we conducted this study based on inquiry and intervention. Objectives: To describe the increase in adherence to hand hygiene through a multimodal strategy based on realistic simulation, inquiry, change of alcohol and training on actions related to infection control. Methods: In May 2018, a survey was administered to healthcare workers (HCW) regarding structure, process, and behavior related to hand hygiene. Training was also performed, which simulated a bed marked with GloGerm (later revealed with the application of black light), performing tasks by professionals, and completing a test. In November 2018, the structure of hand hygiene and points at which the alcoholic product was offered were redefined, and the alcohol-based product and its dispensers were exchanged. In December 2018, an educational campaign on hand hygiene and change disclosure was held. In February 2019, a new survey was applied to employees. Alcohol consumption was measured per patient day in the periods and compared with the historical average. Results: In the first application of the survey, 263 HCW reported dissatisfaction with hand hygiene structure (46% preferred water and soap). Most reported that training and structure would improve adherence. The training took place for 540 HCWs from many different professional positions. Alcohol gel consumption had a sustained increase from an average of 37 mL per patient day in the first semester to 49 mL per patient day in the second semester. After the product change and the new hand hygiene campaign, a second relevant and sustained increase has took place: the first 4-month average in 2019 was 67 mL per patient day. In the second survey, conducted with 187 HCWs, there was an increase in preference for alcohol-based product from a wall dispenser (from 38% to 62%).Funding: NoneDisclosures: None
Substance Use Diagnoses Among Persons with Community-Onset Methicillin-Resistant Staphylococcus aureus Bloodstream Infections
Authors: McCarthy Natalie , Baggs James , Jernigan John , See Isaac , Hatfield Kelly , Reddy Sujan , Gokhale Runa , Wolford Hannah , Fiore Anthony 
Published: November 2020

Background: In recent years, the historic declines in the incidence of methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections (BSIs) in the United States have slowed. We examined trends in the incidence of community-onset (CO) MRSA BSIs among hospitalized persons with and without substance-use diagnoses. Methods: Using data from >200 US hospitals reporting to the Premier Healthcare Database (PHD) during 2012–2017, we conducted a retrospective study among hospitalized persons aged ≥18 years. MRSA BSIs with substance use were defined as hospitalizations having both a blood culture positive for MRSA and at least 1 International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) or ICD-10-CM diagnostic code for substance use including opioids, cocaine, amphetamines, or other substances (excluding cannabis, alcohol, and nicotine). MRSA BSIs were considered community onset when a positive blood culture was collected within 3 days of admission. We assessed annual trends and described characteristics of CO MRSA BSI hospitalizations, stratified by substance use. Results: Of 20,049 MRSA BSIs from 2012 to 2017, 17,634 (88%) were CO. Overall, MRSA BSI incidence decreased 7%, from 178.5 to 166.2 per 100,000 hospitalizations during the study period; However, CO MRSA BSI rates remained stable (152.7 to 149.9 per 100,000 hospitalizations). Among CO MRSA BSIs, 1,838 (10%) were BSIs with substance-use diagnoses; the incidence of CO MRSA BSIs with substance use increased 236% (from 8.2 to 27.6 per 100,000 hospitalizations) and represented a greater proportion of the CO MRSA rate over the study period (Fig. 1). The incidence of CO MRSA BSIs without substance use decreased 15% (from 144.5 to 122.4 per 100,000 hospitalizations). Patients with CO MRSA BSIs with substance use were younger (median, 40 vs 65 years), more likely to be female (50% vs 40%), white (79% vs 69%), and to leave against medical advice (15% vs 1%). Among patients not leaving against medical advice, CO BSI patients with substance-use diagnoses had longer lengths of stay (median, 11 vs 9 days), lower in-hospital mortality (9% vs 14%), and higher hospitalization costs (median, $22,912 vs $17,468) compared to patients without substance-use diagnoses. Conclusions: Although the overall CO MRSA BSI rate remained unchanged from 2012 to 2017, infections with substance use diagnoses increased >3-fold, and infections without substance use diagnoses decreased. These data suggest that the emergence of MRSA associated with substance-use diagnoses threatens potential progress in reducing the incidence of CO MRSA infections. Additional strategies may be needed to prevent MRSA BSI in patients with substance-use diagnoses, and to maintain national progress in the reduction of MRSA infections overall.Funding: NoneDisclosures: None
Successful Control of a Norovirus Outbreak in a Chilean Pediatric Intensive Care Unit
Authors: Benadof Dona , Garcia Vanessa , Cifuentes Paulina , Gaggero Aldo 
Published: November 2020

Background: Noroviruses are nonenveloped, single-stranded RNA viruses belonging to the Caliciviridae family; they cause high-profile outbreaks in healthcare settings, due to their contagiousness, prolonged viral shedding, and ability to survive in the environment. Methods: Description of a norovirus outbreak in a pediatric ICU with multibed rooms. We report the epidemiology, molecular diagnosis, and control. Results: In August and September 2019, an outbreak of acute gastroenteritis affected 13 patients and 26 healthcare workers at an intensive care unit of Roberto Del Río Children’s Hospital, which consists of 22 beds in a multibed-room format. Patients manifested self-limited nondysenteric diarrhea; other symptoms were vomiting (54%) and fever (23%). Healthcare workers reported diarrhea, nausea, vomiting, fever, malaise, and abdominal cramps. The mean age of the patients was 1 year old, all diaper users. The average days of diarrhea in patients was 4 days (2–6 days). There were 87 exposed patients, with an attack rate of 14.9% and 107 exposed staff, with an attack rate of 24.3%. Rotavirus and bacterial etiology were ruled out, and norovirus was subsequently diagnosed in 10 of 13 patients using qRT-PCR; 80% (8 of 10) corresponded with GII norovirus and 20% with a GI (2 of 10). Control measures included enforcement of standard precautions, strict adherence to contact precautions (use of gloves and gowns), hand hygiene before and after patients contact, and mask use if exposure to vomitus. Healthy staff were assigned for patients care. Environmental disinfection twice daily with 1.000 ppm sodium hypochlorite solution was encouraged and supervised with focus on cleaning high-touch surfaces, such as bathrooms, sinks, tables, floors and patient-care items. Active and prospective surveillance were conducted to search for new cases. Infection control practices were coupled with education to staff, patients, and visitors. The outbreak was controlled on September 18, 2019, after 23 days and several interventions, with complete recovery in all cases. Conclusions: We concluded that timely detection of a norovirus outbreak in a healthcare facility is imperative for effective infection control, especially in a multibed-room setting, because of the extended viral shedding in children and the transmission route that included aerosolized viral particles in vomitus. Molecular methods offer a rapid and definitive way to establish etiology, but these tests may not be accessible. Direct contact with infected children and contaminated surfaces and patient-care items were relevant risk factors in this outbreak (which involved both patients and healthcare workers) and contributed with its length.Funding: NoneDisclosures: None