bluuebunny/crossref_metadata_2025_split huggingface dataset:
The reciprocal and nonlinearity relationship between corporate social responsibility and market value added: case study in Indonesia
Authors: Agustinus John 
Published: April 2020

PurposeThis study aims to examine the relationship between corporate social responsibility (CSR) and market value added (MVA) through a more comprehensive analysis of the relationship between the two variables.Design/methodology/approachThe population used in this study is all companies listed on the IDX. Sample selection is done by purposive sampling method where the criteria chosen in this research are: listed on the IDX during 2010–2016 and published its annual financial statements completely. The analysis tools using panel parametric regression are based on the reciprocal relationship (MVA related to CSR, and CSR related to MVA). This model should be linearity, based on RESET test. On the other hand, an alternative model is based on a nonlinearity relationship (the linearity of parametric regression is not fulfilled), the modified panel nonparametric regression (accommodates the reciprocal and nonlinearity relationship).FindingsSocial responsibility or CSR shows a positive relationship with MVA, also the MVA has a positive relationship with CSR. This means that when CSR value increases, then MVA also increases, vice versa. When the company discloses CSR, the company maintains good relationships not only with its shareholders but also with other stakeholders including the community and its environment. Therefore, it can enhance the company's perception and reputation to shareholders that the company is a responsible company, in the sense of being responsible not only to shareholders but also to other stakeholders. This then makes shareholders interested to invest their capital in companies with good CSR. Increased capital by shareholders in the form of stock purchases can affect the high or low stock price of a company; if the company price is high, then the higher the value of its MVA because the stock price is an element of MVA.Originality/valueBased on the aforementioned phenomenon, the relationship has the reciprocal characteristics, which means that CSR has a relationship with MVA; on the other hand, MVA also has a relationship with CSR (with a different time lag). Also, this study detects the nonlinearity relationship between variables shown in Fernandes and Fresly (2017). This part as the originality of this paper focused on the reciprocal and nonlinearity relationship between CSR and MVA.
Data quality of Glasgow Coma Scale and Systolic Blood Pressure in scientific studies involving physician‐staffed emergency medical services: Systematic review
Authors: Tønsager Kristin , Krüger Andreas J. , Ringdal Kjetil G. , Rehn Marius 
Published: April 2020

BackgroundEmergency physicians on‐scene provide highly specialized care to severely sick or injured patients. High‐quality research relies on the quality of data, but no commonly accepted definition of EMS data quality exits. Glasgow Coma Score (GCS) and Systolic Blood Pressure (SBP) are core physiological variables, but little is known about the quality of these data when reported in p‐EMS research. This systematic review aims to describe the quality of pre‐hospital reporting of GCS and SBP data in studies where emergency physicians are present on‐scene.MethodsA systematic literature search was performed using CINAHL, Cochrane, Embase, Medline, Norart, Scopus, SweMed + and Web of Science, in accordance with the PRISMA guidelines. Reported data on accuracy of reporting, completeness and capture were extracted to describe the quality of documentation of GCS and SBP. External and internal validity assessment was performed by extracting a set of predefined variables.ResultsWe included 137 articles describing data collection for GCS, SBP or both. Most studies (81%) were conducted in Europe and 59% of studies reported trauma cases. Reporting of GCS and SBP data were not uniform and may be improved to enable comparisons. Of the predefined external and internal validity data items, 26%‐45% of data were possible to extract from the included papers.ConclusionsReporting of GCS and SBP is variable in scientific papers. We recommend standardized reporting to enable comparisons of p‐EMS.
Children’s mental health and recreation: Limited evidence for associations with screen use
Authors: Kostyrka‐Allchorne Katarzyna , Cooper Nicholas R. , Simpson Andrew , Sonuga‐Barke Edmund J. S. 
Published: April 2020

AbstractAimThis study examined the direct and indirect associations between childhood psychopathology symptoms, screen use, media multitasking and participation in non‐digital recreation.MethodsPsychopathology symptoms, media use, media multitasking, participation in sports, social clubs and reading/games were reported by 520 parents about their 3‐ to 11‐year‐old children. The data were analysed using structural equation modelling.ResultsThere were bidirectional negative associations between sports participation and emotional problems (β = −0.16, P < .001 and β = −0.15, P < .001); attention deficit hyperactivity disorder (ADHD) symptoms were associated with reduced reading/games (β = −0.14, P = .004). A bidirectional positive association was found between media use and conduct problems (β = 0.10, P = .015 and β = 0.14, P = .015). Increased media multitasking was indirectly associated with elevated symptoms of ADHD via a reduction in reading/games (β = 0.10, P = .026). However, there was no evidence that screen use mediated the associations between psychopathology symptoms and non‐digital recreation.ConclusionDepending on the specific psychological difficulties, children are either less likely to participate in non‐digital recreation or are more likely to use screen media or multitask with media. Interventions for children, who experience emotional or behavioural difficulties, are needed to improve participation in non‐digital recreation.
Cardio‐geriatric model of care in acute heart failure: initial experience of a multidisciplinary approach in complex elderly patients
Authors: Mulligan Andrew , Seman Michael , Abramowski Rebecca , Falls Roman , Scholes Elizabeth , Vogrin Sara , Long Claire , Cox Nicholas , Neil Christopher J. 
Published: April 2020

AbstractA ‘cardio‐geriatric’ heart failure model of care was implemented to address the high rates of readmission in elderly acute decompensated heart failure patients. Despite demonstrably intensified management in both the cardiology and geriatric domains, this study did not demonstrate a positive effect on the primary outcome of all cause readmissions at 30 days.
LINC00963 targeting miR‐128‐3p promotes acute kidney injury process by activating JAK2/STAT1 pathway
Authors: Xie Li‐Bo , Chen Bo , Liao Xue , Chen Yi‐Feng , Yang Rui , He Si‐Rong , Pei Li‐Jun , Jiang Rui 
Published: April 2020

AbstractThe role of long non‐coding RNAs (lncRNAs) in kidney diseases has been gradually discovered in recent years. LINC00963, as an lncRNA, was found to be involved in chronic renal failure. However, the role and molecular mechanisms of LINC00963 engaged in acute kidney injury (AKI) were still unclear. In this study, we established rat AKI models by ischaemia and reperfusion (I/R) treatment. Urea and creatinine levels were determined, and histological features of kidney tissues were examined following HE staining. CCK8 assay was chosen to assess the viability of hypoxia‐induced HK‐2 cells. Dual‐luciferase reporter gene assays were performed to verify the target relationship between LINC00963 and microRNA. The mRNA and protein levels were assayed by RT‐qPCR and Western blot, respectively. Annexin V‐FITC/PI and TUNEL staining were used to evaluate apoptosis. LINC00963 was highly expressed in the cell and rat models, and miR‐128‐3p was predicted and then verified as a target gene of LINC00963. Knockdown of LINC00963 reduced acute renal injury both in vitro and in vivo. LINC00963 activated the JAK2/STAT1 pathway to aggravate renal I/R injury. LINC00963 could target miR‐128‐3p to reduce G1 arrest and apoptosis through JAK2/STAT1 pathway to promote the progression of AKI.
The impacts of gene polymorphisms on methotrexate in Chinese psoriatic patients
Authors: Chen M. , Chen W. , Liu P. , Yan K. , Lv C. , Zhang M. , Lu Y. , Qin Q. , Kuang Y. , Zhu W. , Chen X. 
Published: April 2020

AbstractBackgroundMethotrexate (MTX) is the first‐line treatment for psoriasis in China. The metabolic processes of MTX include various proteins and genes. Previous studies have shown that gene polymorphisms had significant impacts on the efficacy of MTX. However, the influence of gene polymorphisms has not been reported in the Chinese psoriatic patients.ObjectiveThe aim of this study was to verify the impacts of candidate genes polymorphisms on the effectiveness of MTX in a Chinese psoriatic population.MethodsIn this study, we enrolled 259 psoriasis patients from two clinical centres. Each of them received MTX treatment at 7.5–15 mg/week for at least 8 weeks. Patients were stratified as responders and non‐responders according to whether the Psoriasis Area and Severity Index score declined more than 75% (PASI75). According to previous reports, 16 single nucleotide polymorphisms (SNPs) were selected and genotyped for each patient using the Sequenom platform. Fisher’s exact test, the chi‐square test, Mann–Whitney tests and ANOVA analyses were used for statistical analysis.ResultsAmong 259 patients, there were 182 males and 77 females, 63 patients with psoriatic arthritis and 196 patients without arthritis phenotype, and the age of all patients ranged from 19 to 70 years (49.7 ± 13.6). The baseline PASI value of patients was 13.8 ± 8.5, and 33.2% of patients achieved a PASI75 response after MTX treatment. Patients carrying the ATP‐binding cassette subfamily B member 1 gene (ABCB1) rs1045642 TT genotype were associated with more severe psoriasis skin lesion (P = 0.032). Furthermore, the ABCB1 rs1045642 TT genotype was found to be more frequent in non‐responders (P = 0.017), especially in moderate‐to‐severe patients (P = 0.002) and patients without psoriatic arthritis (P = 0.026) after MTX treatment.ConclusionWe have demonstrated for the first time that polymorphism of the ABCB1 rs1045642 TT genotype is predictive of a worse clinical response of skin lesions to MTX therapy in a Chinese psoriatic population.
Selective inhibition of anti‐MAG IgM autoantibody binding to myelin by an antigen‐specific glycopolymer
Authors: Aliu Butrint , Demeestere Delphine , Seydoux Emilie , Boucraut José , Delmont Emilien , Brodovitch Alexandre , Oberholzer Thomas , Attarian Shahram , Théaudin Marie , Tsouni Pinelopi , Kuntzer Thierry , Derfuss Tobias , Steck Andreas J. , Ernst Beat , Herrendorff Ruben , Hänggi Pascal 
Published: April 2020

AbstractAnti‐myelin‐associated glycoprotein (MAG) neuropathy is a disabling autoimmune peripheral neuropathy that is caused by circulating monoclonal IgM autoantibodies directed against the human natural killer‐1 (HNK‐1) epitope. This carbohydrate epitope is highly expressed on adhesion molecules such as MAG, a glycoprotein present in myelinated nerves. We previously showed the therapeutic potential of the glycopolymer poly(phenyl disodium 3‐O‐sulfo‐β‐d‐glucopyranuronate)‐(1→3)‐β‐d‐galactopyranoside (PPSGG) in selectively neutralizing anti‐MAG IgM antibodies in an immunological mouse model and ex vivo with sera from anti‐MAG neuropathy patients. PPSGG is composed of a biodegradable backbone that multivalently presents a mimetic of the HNK‐1 epitope. In this study, we further explored the pharmacodynamic properties of the glycopolymer and its ability to inhibit the binding of anti‐MAG IgM to peripheral nerves. The polymer selectively bound anti‐MAG IgM autoantibodies and prevented the binding of patients’ anti‐MAG IgM antibodies to myelin of non‐human primate sciatic nerves. Upon PPSGG treatment, neither activation nor inhibition of human and murine peripheral blood mononuclear cells nor alteration of systemic inflammatory markers was observed in mice or ex vivo in human peripheral blood mononuclear cells. Intravenous injections of PPSGG to mice immunized against the HNK‐1 epitope removed anti‐MAG IgM antibodies within less than 1 hr, indicating a fast and efficient mechanism of action as compared to a B‐cell depletion with anti‐CD20. In conclusion, these observations corroborate the therapeutic potential of PPSGG for an antigen‐specific treatment of anti‐MAG neuropathy.
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The M.A.STE.R.S algorithm for acute visual loss management after facial filler injection
Authors: Graue Gerardo , Ochoa Araujo Dora Aline , Plata Palazuelos Cristina , Núñez Medrano Juan Ángel , López San Juan Fernando José , Sánchez Pereda Daniela , Capiz Correa Daniel Raúl , de Velasco Leopoldo 
Published: April 2020

AbstractObjectiveTo propose an algorithm of treatment for sudden visual loss following filler injections and perform an English‐written literature search for assignment of evidence level and grade recommendation.MethodsAlgorithm of treatment includes ocular physical Maneuvers, hyAluronidase administration, intravenous STEroids, intraocular pressure Reduction, and Supplemental Oxygen (M.A.STE .R.S) based on previous acute management reports. Special consideration for algorithm buildup was made for ophthalmic diseases that share physiopathological features such as central retinal artery occlusion, systemic vasculitis affecting vision, and acute glaucoma. Finally, a systematic cross‐review of the reported cases with visual loss was done to identify the level of evidence and grant a recommendation grade.ResultsA search through PubMed and Medscape databases for English‐written scientific papers using the terms facial filler, retinal artery occlusion, management, treatment, complications, and adverse events quoted a total of 46 papers (190 cases) which were then analyzed. A high variability on management for treatment of sudden visual loss after facial filler injections was observed. This was attributed partially to the great diversity of medical specialists performing cosmetic facial procedures such as dermatologists, plastic surgeons, esthetic doctors and ophthalmologists, and the lack of high evidence level studies.ConclusionsThe proposed algorithm provides an initial guideline based on prior literature reports and physiopathology involving facial filler injection complications. Analysis identified 22 successfully treated cases with vision recovery (11.57%). Ocular physical maneuvers had the best evidence‐based level and grade recommendation (A) for the management of acute vision loss secondary to facial filler injections.
Plasma rich in growth factors injection effectiveness for myofascial pain treatment in masticatory muscles. Randomised controlled trial
Authors: Sakalys Dovydas , Rokicki Jan Pavel , Januzis Gintaras , Kubilius Ricardas 
Published: April 2020

AbstractBackgroundMyofascial pain in masticatory muscles is one of the most common temporomandibular disorder. Nowadays, the most usable treatment methods are based on the muscle taut band cell membrane disruption, which releases the taut band.Platelet‐rich plasma, made with PRGF Endoret® method, gives an opportunity to use platelet‐derived growth factors in treatment processes. It has been proven that platelet‐derived growth factors can relief pain and activate muscle regeneration.ObjectiveTo test a hypothesis that PRGF injections can be effective for treating myofascial pain in masticatory muscles.MethodsFifty adult patients participated in the study. Participants were randomly divided into two groups. The first group received 1‐mL lidocaine injections to trigger point in their masseter muscle. The second group of patients received 1‐mL PRGF injections. The patients' pain was measured by using visual analogue scale (VAS).ResultStatistically significant difference in pain levels before the procedure and 4 weeks after it was found in both groups. There was no statistically significant difference between groups in pain levels before the procedure (P = .063) and 2 weeks after it (P = .123); however, statistically significant difference was noticed 4 weeks after the procedure (P < .001). Four weeks after the procedure, patients' average pain in lidocaine group was 3.4 on VAS, and it was 0.9 in PRGF group.ConclusionsPRGF injections in masseter muscle affected by myofascial pain syndrome are an effective treatment method. PRGF injections more effectively relief myofascial pain in masseter muscle than lidocaine injections.
Are negative beliefs about psychosis associated with emotional distress in adults and young people with such experiences? A meta‐analysis
Authors: Ropaj Esmira , Jones Andrew , Dickson Joanne M. , Gill Zabina , Taylor Peter J. 
Published: April 2020

ObjectiveEmotional distress, including depression and anxiety, is commonly reported amongst individuals experiencing psychosis. The beliefs individuals hold about the meaning of their psychosis may explain the distress they experience. The current meta‐analysis aimed to review the association between beliefs about psychosis experiences and emotional distress.MethodThree electronic databases (PsycINFO, MEDLINE, and CINAHL) were searched using keywords and controlled vocabulary (e.g., Medical Subject Headings) from date of inception to August 2019. A total of 19 eligible papers were identified.ResultsOur random‐effects meta‐analysis revealed that depression and anxiety held moderate association with psychosis beliefs, with perceptions concerning a lack of control over experiences having the strongest association with distress. Longitudinal studies suggest that negative beliefs at baseline are associated with depressive symptoms at follow‐up.ConclusionsThe results suggest that the endorsement of negative beliefs about psychosis is associated with current level of depression and anxiety. The results are consistent with theories of emotional distress in psychosis. However, the small number of longitudinal papers limits what can be concluded about the direction or other temporal characteristics of these relationships. Therapies that target unhelpful beliefs about psychosis may beneficial.Practitioner points

Negative beliefs about experiences of psychosis are associated with greater emotional distress such as depression and anxiety.

Beliefs about a lack of control over experiences had the strongest association with distress.

Interventions that aim to modify or prevent the formation of unhelpful beliefs about psychosis may be beneficial for this population.
Design, Development, and Testing of a Low-Concentration Vanadium Redox Flow Battery
Authors: Lourenssen Kyle , Williams James , Ahmadpour Faraz , Clemmer Ryan , Gadsden S. Andrew , Tasnim Syeda Humaira 
Published: April 2020

Abstract
The purpose of this paper is to highlight the design, development, and testing of a low-concentration vanadium redox flow battery (VRFB). The low-cost implementation has a 7 cm × 7 cm active membrane area and an electrolyte volume of 450 mL for each positive and negative electrolyte. The electrolyte concentration is approximately 0.066 M vanadium. An H-cell for performing electrolysis with the electrolytes is developed, and the process and method for creating the electrolyte for this low-concentration implementation are described and documented. The maximum power density and energy efficiency of the battery among tests between 500 and 800 mA are 1.32 W/L and 28.51%, respectively. Results are presented in terms of polarization curves, charge/discharge cycles, and voltage, coulombic, and energy efficiencies. Adaptation of a COMSOL Multiphysics model is implemented to compare the computational performance figures and the results of our VRFB implementation. The numerical results agree with experimentation, and differences in the results can be attributed to the losses present in the experimental tests. The proposed battery and design are intended to investigate the performance and feasibility of a low-concentration VRFB. The ultimate long-term objective of this research is the development of a novel, cost-effective, and safe redox flow battery using hydrogen peroxide as one of the electrolytes.
Wall-Normal Velocity Correlations in a Zero Pressure Gradient Turbulent Boundary Layer
Authors: Morilhat Sylvain , Chedevergne François , Micheli Francis , Simon Frank 
Published: April 2020

Abstract
An experimental campaign dedicated to the characterization of the wall-normal velocity correlations in a zero pressure gradient turbulent boundary layer was performed. A double set of laser Doppler velocimetry (LDV) benches were used to access two-point two-time correlations of the wall-normal velocity. The measurements analysis confirms several important hypotheses classically made to model wall pressure spectra from the velocity correlations. In particular, the ratio of the wall-normal Reynolds stress to the turbulent shear stress is confirmed to exhibit a large plateau in the logarithmic region. In addition, Taylor's hypothesis of frozen turbulence is well recovered for the wall-normal velocity fluctuations. The convection velocity for the wall-normal velocity fluctuations is also shown to evolve across the boundary layer, according to the mean velocity profile. Furthermore, the decorrelation time scale of velocity correlations appears to be increasing throughout the boundary layer thickness in accordance with the increase of the convection velocity. The results obtained with this original campaign will help improving models for wall pressure spectra, especially those based on the resolution of the Poisson equation for the pressure for which the wall pressure correlations are related to the wall-normal velocity correlations.
Psychological interventions to improve glycemic control in adults with type 2 diabetes: a systematic review and meta-analysis
Authors: Winkley Kirsty , Upsher Rebecca , Stahl Daniel , Pollard Daniel , Brennan Alan , Heller Simon R , Ismail Khalida 
Published: April 2020

The quality of evidence that psychological interventions are effective in improving glycemic control in adults with type 2 diabetes (T2D) is weak.We conducted a systematic review and meta-analysis of psychological interventions in T2D to assess whether their effectiveness in improving glycemic levels has improved over the past 30 years. We applied the protocol of a systematic review and aggregate meta-analysis conducted to January 2003. We added network meta-analysis (NMA) to compare intervention and control group type against usual care. MEDLINE, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, EMBASE, Cochrane Controlled Trials Database, Web of Science, and Dissertation Abstracts International were searched from January 2003 to July 2018. Only randomized controlled trials (RCT) of psychological interventions for adults with T2D reported in any language were included. The primary outcome was change in glycemic control (glycated hemoglobin (HbA1c) in mmol/mol). Data were extracted from study reports and authors were contacted for missing data.94 RCTs were eligible for inclusion in the systematic review since the last review. In 70 RCTs (n=14 796 participants) the pooled mean difference in HbA1c in those randomized to psychological intervention compared with control group was −0.19 (95% CI −0.25 to −0.12), equivalent to a reduction in HbA1c of 3.7 mmol/mol, with moderate heterogeneity across studies (I2=64.7%, p<0.001). NMA suggested the probability of intervention effectiveness is highest for self-help materials, cognitive–behavioral therapy, and counseling, compared with usual care. Limitations of this study include that there is a possibility that some studies may have been missed if diabetes did not appear in the title or abstract.The effectiveness of psychological interventions for adults with T2D have minimal clinical benefit in improving glycemic control.PROSPERO registration numberCRD42016033619.