bluuebunny/crossref_metadata_2025_split huggingface dataset:
Free Response of a Rotational Nonlinear Energy Sink: Complete Dissipation of Initial Energy for Small Initial Rectilinear Displacements
Authors: Ding Ke , Pearlstein Arne J. 
Published: September 2020

Abstract
For two combinations of a dimensionless rotational damping parameter and a dimensionless inertial coupling parameter, we consider free response of a rectilinearly vibrating linearly sprung primary mass inertially coupled to damped rotation of a second mass, for which Gendelman et al. (2012, “Dynamics of an Eccentric Rotational Nonlinear Energy Sink,” ASME J. Appl. Mech. 79(1), 011012) developed equations of motion in the context of a rotational nonlinear energy sink (NES) with no direct damping of the rectilinear motion. For dimensionless initial rectilinear displacements comparable with those considered by Gendelman et al., we identify a region in the motionless projection of the initial condition space (i.e., for zero values of the initial rectilinear and rotational velocities) in which every initial condition leads to a previously unrecognized zero-energy solution, with all initial energy dissipated by rotation. We also show that the long-time nonrotating, rectilinear solutions of the type found by Gendelman et al. are (orbitally) stable only in limited ranges of amplitude. Finally, we show how direct viscous damping of rectilinear motion of the primary mass affects dissipation, and that results with no direct rectilinear dissipation provide excellent guidance for performance when direct rectilinear dissipation occurs. Some applications are discussed.
Ancient Adélie penguin colony revealed by snowmelt at Cape Irizar, Ross Sea, Antarctica
Authors: Emslie Steven D. 
Published: September 2020

Abstract
The Ross Sea (Antarctica) is one of the most productive marine ecosystems in the Southern Ocean and supports nearly one million breeding pairs of Adélie penguins (Pygoscelis adeliae) annually. There also is a well-preserved record of abandoned penguin colonies that date from before the Last Glacial Maximum (&gt;45,000 14C yr B.P.) through the Holocene. Cape Irizar is a rocky cape located just south of the Drygalski Ice Tongue on the Scott Coast. In January 2016, several abandoned Adélie penguin sites and abundant surface remains of penguin bones, feathers, and carcasses that appeared to be fresh were being exposed by melting snow and were sampled for radiocarbon analysis. The results indicate the “fresh” remains are actually ancient and that three periods of occupation by Adélie penguins are represented beginning ca. 5000 calibrated calendar (cal.) yr B.P., with the last occupation ending by ca. 800 cal. yr B.P. The presence of fresh-appearing remains on the surface that are actually ancient in age suggests that only recently has snowmelt exposed previously frozen carcasses and other remains for the first time in ∼800 yr, allowing them to decay and appear fresh. Recent warming trends and historical satellite imagery (Landsat) showing decreasing snow cover on the cape since 2013 support this hypothesis. Increased δ13C values of penguin bone collagen further indicate a period of enhanced marine productivity during the penguin “optimum”, a warm period at 4000–2000 cal. yr B.P., perhaps related to an expansion of the Terra Nova Bay polynya with calving events of the Drygalski Ice Tongue.
Concurrent validity of a touchscreen application to detect early cognitive delay
Authors: Twomey Deirdre Marie , Ahearne Caroline , Hennessy Emma , Wrigley Conal , De Haan Michelle , Marlow Neil , Murray Deirdre M 
Published: September 2020

ObjectiveTo explore the ability of an interactive screening tool to identify cognitive delay in children aged 18 to 24 months.DesignChildren were assessed using the Bayley Scale of Infant and Toddler Development—third edition (BSID-III) and a touchscreen measure of problem-solving (Babyscreen V.1.5). We examined the internal consistency and concurrent validity between the two measures. A BSID-III cognitive composite score (BSID-IIIcc) ≤1 SD below population mean was used to indicate a low average cognitive ability.Results87 children with a mean (SD) age of 20.4 (1.3) months who experienced complications at delivery (n=53) and healthy age-matched controls (n=34) were included in the study. A moderate positive correlation between the BSID-IIIcc and the total number of tasks completed on the Babyscreen suggested reasonable concurrent validity (r=0.414, p<0.001). Children with a BSID-IIIcc ≤90 had lower median (IQR) Babyscreen score (7 (6, 8.5) vs 11 (8.5, 13); p=0.003) and a lower median (IQR) age-adjusted z-score (BST z-score) for number of items completed compared with those >90 (−1.08 (−1.5 to −0.46) vs 0.31 (−0.46 to 0.76); p=0.001). The area under the receiver operating characteristic curve for the prediction of a low normal BSID-IIIcc was 0.787 (CI 0.64 to 0.93). A BST z-score of <−0.44 yielded 82.4% sensitivity and 71.4% specificity in identifying children with cognitive delay.ConclusionsA touchscreen-based application has concurrent validity with the BSID-IIIcc and could be used to screen for cognitive delay at 18–24 months of age.
International Olympic Committee (IOC) Sport Mental Health Assessment Tool 1 (SMHAT-1) and Sport Mental Health Recognition Tool 1 (SMHRT-1): towards better support of athletes’ mental health
Authors: Gouttebarge Vincent , Bindra Abhinav , Blauwet Cheri , Campriani Niccolo , Currie Alan , Engebretsen Lars , Hainline Brian , Kroshus Emily , McDuff David , Mountjoy Margo , Purcell Rosemary , Putukian Margot , Reardon Claudia L , Rice Simon M , Budgett Richard 
Published: September 2020

ObjectivesTo develop an assessment and recognition tool to identify elite athletes at risk for mental health symptoms and disorders.MethodsWe conducted narrative and systematic reviews about mental health symptoms and disorders in active and former elite athletes. The views of active and former elite athletes (N=360) on mental health symptoms in elite sports were retrieved through an electronic questionnaire. Our group identified the objective(s), target group(s) and approach of the mental health tools. For the assessment tool, we undertook a modified Delphi consensus process and used existing validated screening instruments. Both tools were compiled during two 2-day meeting. We also explored the appropriateness and preliminary reliability and validity of the assessment tool.Sport Mental Health Assessment Tool 1 and Sport Mental Health Recognition Tool 1The International Olympic Committee Sport Mental Health Assessment Tool 1 (SMHAT-1) was developed for sports medicine physicians and other licensed/registered health professionals to assess elite athletes (defined as professional, Olympic, Paralympic or collegiate level; aged 16 years and older) potentially at risk for or already experiencing mental health symptoms and disorders. The SMHAT-1 consists of: (i) triage with an athlete-specific screening tool, (ii) six subsequent disorder-specific screening tools and (iii) a clinical assessment (and related management) by a sports medicine physician or licensed/registered mental health professional (eg, psychiatrist and psychologist). The International Olympic Committee Sport Mental Health Recognition Tool 1 (SMHRT-1) was developed for athletes and their entourage (eg, friends, fellow athletes, family and coaches).ConclusionThe SMHAT-1 and SMHRT-1 enable that mental health symptoms and disorders in elite athletes are recognised earlier than they otherwise would. These tools should facilitate the timely referral of those athletes in need for appropriate support and treatment.
Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis
Authors: Thom Howard , Jansen Jeroen , Shafrin Jason , Zhao Lauren , Joseph George , Cheng Hung-Yuan , Gupta Subhajit , Shah Nirmish 
Published: September 2020

ObjectivesTreatment options for preventing vaso-occlusive crises (VOC) among patients with sickle cell disease (SCD) are limited, especially if hydroxyurea treatment has failed or is contraindicated. A systematic literature review (SLR) and network meta-analysis (NMA) were conducted to evaluate the efficacy and safety of crizanlizumab for older adolescent and adult (≥16 years old) SCD patients.MethodsThe SLR included randomised controlled trials (RCTs) and uncontrolled studies. Bayesian NMA of VOC, all-cause hospitalisation days and adverse events were conducted.ResultsThe SLR identified 51 studies and 9 RCTs on 14 treatments that met the NMA inclusion criteria. The NMA found that crizanlizumab 5.0 mg/kg was associated with a reduction in VOC (HR 0.55, 95% credible interval (0.43, 0.69); Bayesian probability of superiority >0.99), all-cause hospitalisation days (0.58 (0.50, 0.68); >0.99) and no evidence of difference on adverse events (0.91 (0.59, 1.43) 0.66) or serious adverse events (0.93 (0.47, 1.87); 0.59) compared with placebo. The HR for reduction in VOC for crizanlizumab relative to L-glutamine was (0.67 (0.50, 0.88); >0.99). These results were sensitive to assumptions regarding whether patient age is an effect modifier.ConclusionsThis NMA provides preliminary evidence comparing the efficacy of crizanlizumab with other treatments for VOC prevention.
Burden of scrub typhus among patients with acute febrile illness attending tertiary care hospital in Chitwan, Nepal
Authors: Thapa Sangita , Hamal Pradip , Chaudhary Navin Kumar , Sapkota Lokendra Bahadur , Singh Jaya Prasad 
Published: September 2020

ObjectivesScrub typhus is an emerging neglected tropical disease, reported from many parts of Asia including Nepal. This study aims to determine the seroepidemiology of scrub typhus among febrile patients attending Chitwan Medical College Teaching Hospital (CMC-TH), Bharatpur, Nepal.Study design and settingThis was a hospital laboratory-based prospective study conducted in CMC-TH (a 750-bed hospital) located in Bharatpur, Chitwan district of Nepal.ParticipantsA total of 1797 patients visiting CMC-TH with acute febrile illness (temperature more than 38°C) were enrolled in this study.MethodsA total of 1797 blood samples were collected from patients presenting with acute febrile illness. The samples were processed for detection of antibody for scrub typhus by ELISA for specific IgM antibody and Weil-Felix test.ResultsOut of 1797 serum sample of febrile patients, 524 (29.2%) were scrub typhus positive. Maximum seropositive cases were from Chitwan district, 271 (51.7%) with predominance among women, 314 (35.9%). Scrub typhus was common among age group 51–60 years (37.2%) and farmers, 182 (37.8%). Highest seropositivity was found in July, 60 (57.7%). Fever was common clinical symptom. Thrombocytopenia was seen in 386 (73.7%) and raised transaminase aspartate aminotransferase, 399 (76.1%) among seropositive cases. Weil-Felix test positive were 397 (22.1%) and IgM ELISA positive were 524 (29.2%). The correlation between IgM ELISA and Weil-Felix test showed statistically significant association (r=0.319, p<0.001).ConclusionHigh prevalence of scrub typhus implies that patients with acute febrile illness should be investigated for scrub typhus with high priority. There is utmost need of reliable diagnostic facilities at all levels of healthcare system in Nepal. Infection with scrub typhus was found high and this calls for an urgent need to introduce vaccine against scrub typhus. More sustain and vigorous awareness programmes need to be promoted for early diagnosis, treatment and control.
Comparative efficacy and safety of intra-articular analgesics after knee arthroscopy: a Bayesian network meta-analysis protocol
Authors: He Yuchen , He Hongyi , Xie Dong-Xing , Li Xiaoxiao , Wang Yilun 
Published: September 2020

IntroductionMost of the patients who received arthroscopic knee surgery will suffer moderate to severe pain, which can delay the rehabilitation process and increase the risk of postoperative complications. Therefore, seeking a safe and effective postoperative analgesia is necessary for promoting the application of arthroscopic surgery. This protocol aims to detail a planned systematic review and meta-analysis on the comparative efficacy and safety of single-dose intra-articular injection of analgesics for pain relief after knee arthroscopy.Method and analysisPubMed, Embase, Web of Science and Cochrane Library will be searched from inception to 1 June 2020 to retrieve randomised controlled trials (RCTs) that compared the commonly used single-dose intra-articular analgesics (ie, morphine; bupivacaine (including levobupivacaine); ropivacaine and magnesium alone or in combination) with placebo or between each other for postoperative pain relief among patients who had received knee arthroscopy. The primary outcome is pain intensity at 2-hour and 24-hour postoperatively; the secondary outcomes include side effects (eg, knee effusion, nausea, vomiting and flushing), the number of patients requiring supplementary analgesia and the time to first analgesic request. The methodological quality of the included RCTs will be assessed based on the Cochrane risk of bias table. The Bayesian network meta-analysis will be conducted using WinBUGS V.1.4.3.Ethics and disseminationSince no private or confidential patient data will be contained in the reporting, approval from an ethics committee is not required. Our study raises no ethical issue, and the results will be published in a peer-reviewed journal.PROSPERO registration numberCRD42019130876.
Sex-specific differences in children attending the emergency department: prospective observational study
Authors: Zachariasse Joany M , Borensztajn Dorine M , Nieboer Daan , Alves Claudio F , Greber-Platzer Susanne , Keyzer-Dekker Claudia M G , Maconochie Ian K , Steyerberg Ewout W , Smit Frank J , Moll Henriëtte A 
Published: September 2020

ObjectiveTo assess the role of sex in the presentation and management of children attending the emergency department (ED).DesignThe TrIAGE project (TRiage Improvements Across General Emergency departments), a prospective observational study based on curated electronic health record data.SettingFive diverse European hospitals in four countries (Austria, The Netherlands, Portugal, UK).ParticipantsAll consecutive paediatric ED visits of children under the age of 16 during the study period (8–36 months between 2012 and 2015).Main outcome measuresThe association between sex (male of female) and diagnostic tests and disease management in general paediatric ED visits and in subgroups presenting with trauma or musculoskeletal, gastrointestinal and respiratory problems and fever. Results from the different hospitals were pooled in a random effects meta-analysis.Results116 172 ED visits were included of which 63 042 (54%) by boys and 53 715 (46%) by girls. Boys accounted for the majority of ED visits in childhood, and girls in adolescence. After adjusting for age, triage urgency and clinical presentation, girls had more laboratory tests compared with boys (pooled OR 1.10, 95% CI 1.05 to 1.15). Additionally, girls had more laboratory tests in ED visits for respiratory problems (pooled OR 1.15, 95% CI 1.04 to 1.26) and more imaging in visits for trauma or musculoskeletal problems (pooled OR 1.10, 95% CI 1.01 to 1.20) and respiratory conditions (pooled OR 1.14, 95% CI 1.05 to 1.24). Girls with respiratory problems were less often treated with inhalation medication (pooled OR 0.76, 95% CI 0.70 to 0.83). There was no difference in hospital admission between the sexes (pooled OR 0.99, 95% CI 0.95 to 1.04).ConclusionIn childhood, boys represent the majority of ED visits and they receive more inhalation medication. Unexpectedly, girls receive more diagnostic tests compared with boys. Further research is needed to investigate whether this is due to pathophysiological differences and differences in disease course, whether girls present signs and symptoms differently, or whether sociocultural factors are responsible.
Childhood overweight and obesity and back pain risk: a cohort study of 466 997 children
Authors: Palmer Antony J , Poveda Jose Luis , Martinez-Laguna Daniel , Reyes Carlen , de Bont Jeroen , Silman Alan , Carr Andrew J , Duarte-Salles Talita , Prieto-Alhambra Daniel 
Published: September 2020

ObjectivesTo assess the association between age, sex, socioeconomic group, weight status and back pain risk in a large general population cohort of children.Design and settingA dynamic cohort of children aged 4 years in the Information System for Research in Primary Care (SIDIAP) electronic primary care records data in Catalonia. Multivariable Cox models were fitted to explore the association between back pain and weight status categories according to the WHO 2007 growth reference groups (body mass index for age z-score). Models were adjusted for age, sex, socioeconomic status and nationality.ParticipantsChildren seen at age 4 years at paediatric primary care clinics between 1 January 2006 and 31 December 2013 and followed up until 31 December 2016 or age 15 years.Outcome measuresIncident back pain registered by paediatricians at primary care using the International Statistical Classification of Diseases and Health Related Problems, 10th Edition code M54.Results466 997 children were followed for a median 5.0 years (IQR 5.1). In multivariable models, overweight and obesity increased back pain risk, with adjusted HRs of 1.18 (95% CI 1.09 to 1.27) and 1.34 (95%CI 1.19 to 1.51) for overweight and obesity, respectively. Females were at greater risk of back pain than males with adjusted HR 1.40 (95%CI 1.35 to 1.46). Adjusted HR was 1.43 (95%CI 1.33 to 1.55) for back pain in children from the most deprived socioeconomic groups compared with the least deprived socioeconomic groups.ConclusionsMaintaining a healthy weight from an early age may reduce the prevalence of back pain in both children and adults. Overweight female children from deprived socioeconomic groups are at greatest risk of back pain and represent a target population for intervention.
Death and dying in prehospital care: what are the experiences and issues for prehospital practitioners, families and bystanders? A scoping review
Authors: Myall Michelle , Rowsell Alison , Lund Susi , Turnbull Joanne , Arber Mick , Crouch Robert , Pocock Helen , Deakin Charles , Richardson Alison 
Published: September 2020

ObjectiveTo identify the factors that shape and characterise experiences of prehospital practitioners (PHPs), families and bystanders in the context of death and dying outside of the hospital environment where PHPs respond.DesignA scoping review using Arksey and O’Malley’s five-stage framework. Papers were analysed using thematic analysis.Data sourcesMEDLINE; Embase; CINAHL; Scopus; Social Sciences Citation Index (Web of Science), ProQuest Dissertations & Theses A&I (Proquest), Health Technology Assessment database; PsycINFO; Grey Literature Report and PapersFirst were searched from January 2000 to May 2019.Eligibility criteria for selecting studiesQualitative and mixed methods studies reporting the experiences of PHPs, families and bystanders of death and dying in prehospital settings as a result of natural causes, trauma, suicide and homicide, >18 years of age, in Europe, USA, Canada, Australia and New Zealand.ResultsSearches identified 15 352 papers of which 51 met the inclusion criteria. The review found substantial evidence of PHP experiences, except call handlers, and papers reporting family and bystander experiences were limited. PHP work was varied and complex, while confident in clinical work, they felt less equipped to deal with the emotion work, especially with an increasing role in palliative and end-of-life care. Families and bystanders reported generally positive experiences but their support needs were rarely explored.ConclusionsTo the best of our knowledge this is the first review that explores the experiences of PHPs, families and bystanders. An important outcome is identifying current gaps in knowledge where further empirical research is needed. The paucity of evidence suggested by this review on call handlers, families and bystanders presents opportunities to investigate their experiences in greater depth. Further research to address the current knowledge gaps will be important to inform future policy and practice.
Use and impact of social prescribing: a mixed-methods feasibility study protocol
Authors: Jani Anant , Liyanage Harshana , Hoang Uy , Moore Lucy , Ferreira Filipa , Yonova Ivelina , Tzortziou Brown Victoria , de Lusignan Simon 
Published: September 2020

IntroductionSocial prescribing aims to address social determinants of health, which account for 80%–90% of health outcomes, but the evidence base behind it is limited due to a lack of data linkingsocial prescribing activity and outcomes.Methods and analysisThe objective of the quantitative component of this feasibility studyisto identify the characteristics of individuals who receive social prescriptions and describe the use and estimate the impact of social prescribing; the latter will be done on a homeless subgroup. We will use the Oxford Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) primary care sentinel network, whose general practicescover a population of over 4 000 000 patients. Social prescribing data will be extracted onall recorded patients for 5 years up to 31 January 2020. The objective for the qualitative component of the study isto explore approaches to understand the contextual factors that will have influenced our quantitative findings to identify mechanisms to encourage adoption of social prescribing in primary care while improving data quality. Itwill comprise up to three 90–120 minute advisory group meetings for six to eight participants. Participants will be recruited based on their experience of delivering primary care within Oxfordshire and Surrey. The advisory group outputs will be analysed using framework analysis and will be used to create a survey instrument consisting of statements that surveyees, who will consist of primary care practitioners within the RCGP RSC, can agree or disagree with.Ethics and disseminationAll RCGP RSC data are pseudonymised at the point of data extraction. No personally identifiable data are required for this investigation. This protocol follows the Good Reporting of a Mixed Methods Study checklist. The study results will be published in a peer-reviewed journal and the dataset will be available to other researchers.