bluuebunny/crossref_metadata_2025_split huggingface dataset:
Body Composition During Pregnancy: Longitudinal Changes and Method Comparisons
Authors: Bosaeus Marja , Andersson-Hall Ulrika , Andersson Louise , Karlsson Therese , Ellegård Lars , Holmäng Agneta 
Published: February 2020

AbstractThe Pregnancy Obesity Nutrition and Child Health study is a longitudinal study of reproductive health. Here we analyzed body composition of normal-weight and obese Swedish women by three methods during each trimester of pregnancy. Cross-sectional and longitudinal fat mass estimates using quantitative magnetic resonance (QMR) and bioelectrical impedance analysis (BIA) (Tanita MC-180MA-III) were compared with fat mass determined by air displacement plethysmography (ADP) in pregnancy weeks 8–12, 24–26, and 35–37 in normal-weight women (n = 122, BMI = 22.1 ± 1.6 kg/m2) and obese women (n = 29, BMI = 34.6 ± 3.6 kg/m2). ADP results were calculated from pregnancy-adjusted fat-free mass densities. Mean fat mass by QMR and ADP were similar in obese women, although with wide limits of agreement. In normal-weight women, QMR overestimated mean fat mass in all trimesters, with systematic overestimation at low fat mass values in trimesters 1 and 3. In obese women, fat mass by BIA was grossly underestimated and imprecise in all trimesters, especially at higher values in trimester 2. In normal-weight women, fat mass by BIA was moderately lower than by ADP in trimester 1, similar in trimester 2, and moderately higher in trimester 3. QMR and ADP assessed fat mass changes similarly in obese women, whereas BIA overestimated fat mass changes in normal-weight women. Mean fat mass and fat mass changes by QMR and pregnancy-adjusted ADP were similar in pregnant obese women. Mean fat mass by QMR and fat mass changes by BIA were higher than corresponding values determined by pregnancy-adjusted ADP in normal-weight women.
Schizophrenia-Associated MicroRNA–Gene Interactions in the Dorsolateral Prefrontal Cortex
Authors: Santarelli Danielle M. , Carroll Adam P. , Cairns Heath M. , Tooney Paul A. , Cairns Murray J. 
Published: February 2020

Abstract
Schizophrenia-associated anomalies in gene expression in postmortem brain can be attributed to a combination of genetic and environmental influences. Given the small effect size of common variants, it is likely that we may only see the combined impact of some of these at the pathway level in small postmortem studies. At the gene level, however, there may be more impact from common environmental exposures mediated by influential epigenomic modifiers, such as microRNA (miRNA). We hypothesise that dysregulation of miRNAs and their alteration of gene expression have significant implications in the pathophysiology of schizophrenia. In this study, we integrate changes in cortical gene and miRNA expression to identify regulatory interactions and networks associated with the disorder. Gene expression analysis in post-mortem prefrontal dorsolateral cortex (BA 46) (n = 74 matched pairs of schizophrenia, schizoaffective, and control samples) was integrated with miRNA expression in the same cohort to identify gene–miRNA regulatory networks. A significant gene–miRNA interaction network was identified, including miR-92a, miR-495, and miR-134, which converged with differentially expressed genes in pathways involved in neurodevelopment and oligodendrocyte function. The capacity for miRNA to directly regulate gene expression through respective binding sites in BCL11A, PLP1, and SYT11 was also confirmed to support the biological relevance of this integrated network model. The observations in this study support the hypothesis that miRNA dysregulation is an important factor in the complex pathophysiology of schizophrenia.
Generation and imaging of a tunable ultrafast intensity-rotating optical field with a cycle down to femtosecond region
Authors: Zeng Xuanke , Zheng Shuiqin , Cai Yi , Wang Hongyu , Lu Xiaowei , Wang Honggeng , Li Jingzhen , Xie Weixin , Xu Shixiang 
Published: February 2020

A tunable ultrafast intensity-rotating optical field is generated by overlapping a pair of 20 Hz, 800 nm chirped pulses with a Michelson interferometer (MI). Its rotating rate can be up to 10 trillion radians per second (

$\text{Trad}/\text{s}$

), which can be flexibly tuned with a mirror in the MI. Besides, its fold rotational symmetry structure is also changeable by controlling the difference from the topological charges of the pulse pair. Experimentally, we have successfully developed a two-petal lattice with a tunable rotating speed from

$3.9~\text{Trad}/\text{s}$

up to

$11.9~\text{Trad}/\text{s}$

, which is confirmed by our single-shot ultrafast frame imager based on noncollinear optical-parametric amplification with its highest frame rate of 15 trillion frames per second (Tfps). This work is carried out at a low repetition rate. Therefore, it can be applied at relativistic, even ultrarelativistic, intensities, which usually operate in low repetition rate ultrashort and ultraintense laser systems. We believe that it may have application in laser-plasma-based accelerators, strong terahertz radiations and celestial phenomena.
BOXING, RACE, AND BRITISH IDENTITY, 1945–1962
Authors: JOHNES MARTIN , TAYLOR MATTHEW 
Published: February 2020

AbstractWith a formal colour bar on British championships operating until 1948, boxing had long been a site of racial discrimination. The abolition of the sport's colour bar was recognition of the wrongness of racial exclusion and it was followed by a celebration of black fighters as local and national heroes. The sport became a rare space where black men could be spoken about, discussed, and celebrated without primary reference to their colour. However, race was never irrelevant, especially as the number of black boxers rose with wider patterns of migration. Race was thus widely discussed in boxing, although there was rarely open discussion of racism. This absence, along with black successes in the ring, masked deep levels of both structural and interpersonal prejudice. Racial differences remained accepted as common sense by white Britons. Indeed, immigration intensified racism in Britain, changing the perceived position of people of colour from exotic novelties to threats to society. Boxing is thus a reminder of the contradictory dynamics of race. Formal mechanisms of exclusion could be removed, while informal mechanisms intensified. Individuals could be celebrated, while people of colour as a group were looked down upon. Black achievements could simultaneously reinforce ideas of black inferiority.
Investigating the attitude of patients with chronic diseases about using mobile health
Authors: Abbasi Reza , Zare Sahar , Ahmadian Leila 
Published: February 2020

BackgroundMobile health (mHealth) due to its popularity and accessibility can be widely applied in different health areas such as the management of chronic diseases. However, its success depends on the acceptance of their users. Therefore, the aim of this study was to survey the attitudes of patients with chronic disease toward mHealth technology and their willingness to use it.MethodsThis study was conducted within a 2-year period (2016–2018) to determine and compare the attitude and willingness of patients with asthma, diabetes, and multiple sclerosis (MS) toward using mHealth technology in a province in Iran.ResultsIn total, 222 patients participated in this study. More than 93 percent of the patients with diabetes and MS, and 65 percent of the asthmatic patients preferred using mHealth services rather than consulting a physician (p < .0001). About 98, 94, and 49 percent of the MS, diabetic, and asthmatic patients, respectively felt comfortable if their health conditions checked by physicians through mHealth technology (p < .0001).ConclusionsOur results showed that the majority of the patients felt comfortable and preferred using mHealth technology rather than consulting the physicians. The attitudes of diabetic and MS patients toward mHealth technology were rather more positive compared to asthmatic patient attitude. These results may be helpful for the developers of mHealth technology, and researchers who design mHelath interventions for patients with chronic disease.
Significant chick loss after early fast ice breakup at a high-latitude emperor penguin colony
Authors: Schmidt Annie E. , Ballard Grant 
Published: February 2020

AbstractEmperor penguins require stable fast ice, sea ice anchored to land or ice shelves, on which to lay eggs and raise chicks. As the climate warms, changes in sea ice are expected to lead to substantial declines at many emperor penguin colonies. The most southerly colonies have been predicted to remain buffered from the direct impacts of warming for much longer. Here, we report on the unusually early breakup of fast ice at one of the two southernmost emperor penguin colonies, Cape Crozier (77.5°S), in 2018, an event that may have resulted in a substantial loss of chicks from the colony. Fast ice dynamics can be highly variable and dependent on local conditions, but earlier fast ice breakup, influenced by increasing wind speed, as well as higher surface air temperatures, is a likely outcome of climate change. What we observed at Cape Crozier in 2018 highlights the vulnerability of this species to untimely storm events and could be an early sign that even this high-latitude colony is not immune to the effects of warming. Long-term monitoring will be key to understanding this species' response to climate change and altered sea ice dynamics.
The policy mood in Spain: the thermostat in a warm climate, 1978–2017
Authors: Bartle John , Bosch Agustí , Orriols Lluís 
Published: February 2020

AbstractRepresentative democracies are supposed to be uniquely virtuous in that they ensure that public preferences drive public policy. Dynamic representation is the outcome of a recurring interaction between electorate and parties that can be observed at the macro level. Preferences can shape government policy via two possible mechanisms. ‘Policy accomodation’ suggests that governments respond directly to the electorate’s preferences. ‘Electoral turnover’, on the other hand, assumes that preferences shape policy indirectly. Parties pursue their ideological goals, and public preferences respond ‘thermostatically’ by moving in the opposite direction to policy. This causes voters to switch votes and eventually leads to a turnover of power from one ‘side’ to ‘the other’. In this paper, we estimate preferences for government activity (‘the policy mood’) in Spain between 1978 and 2017. We show that mood responds ‘thermostatically’ to policy. Variations in mood are associated with support for parties. Policy is driven by party control but is not thermostatically responsive to mood. It appears that in Spain – like Britain – dynamic representation can only be achieved by electoral turnover. We consider the implications of this for our understanding of how representation works.
The Rule of Law, the International Legal Order, and the Foreign Policy of Small States
Authors: MENON Sundaresh 
Published: February 2020

AbstractThe rule of law bears a special meaning in the context of the international legal order, where there is no clear vertical hierarchy or sovereign. The international rule of law strives to curb the excess autonomy of individual states for the common good. Although there is considerable scepticism about whether the international rule of law actually exists, states largely do behave as if international law is truly “law”, and international obligations are also more enforceable now than ever before. But there have been and will be moments when the international rule of law is interrupted by major powers. In an interdependent world that is both capable of and prone to inflicting unimaginable destruction, the strategy for small states unable to defend themselves directly is to create the conditions that will best promote their survival, and that is accomplished by pursuing and promoting the rule of law both domestically and internationally.
The Effect of Retrieval Practice on Transitive	Inference
Authors: Picklesimer Milton E. , Buchin Zachary L. , Mulligan Neil W. 
Published: February 2020

Abstract. Compared to restudying, retrieval practice has often been found to enhance memory (the testing effect). However, it has been proposed that materials with high element interactivity may not benefit from retrieval practice. Transitive inference (TI) requires just such interactivity, in which information must be combined across multiple learning elements or premises. The current study employed a 7-element TI paradigm in which participants initially learned a set of premises (e.g., A > B, B > C, C > D, etc.), then engaged in either restudy or retrieval practice with the premises, and then were given a final test that assessed memory for the original premises and one’s ability to make transitive inferences about them (e.g., to infer that B > D). Three experiments examined TI on final tests with retention intervals of a few minutes (Experiment 1), 2 days (Experiment 2), or up to a week (Experiment 3). Retrieval practice consistently failed to enhance transitive inference. Furthermore, retrieval practice significantly reduced TI in Experiment 1. Across experiments, TI was numerically worse in the retrieval-practice than restudy condition in 4 of 5 comparisons, and a small-scale meta-analysis revealed a significant negative effect of retrieval practice on TI.
New Vary‐Chap Scale Height Profile Retrieved From COSMIC Radio Occultation Data
Authors: Wu M. J. , Guo P. , Chen Y. L. , Fu N. F. , Hu X. G. , Hong Z. J. 
Published: February 2020

AbstractThe Global Navigation Satellite System radio occultation technique provides materials for the validation of a mathematical description of the topside ionosphere up to the low Earth orbit (LEO) satellite altitude. An attempt to represent the topside electron density profile is using α‐Chapman function with a continuously varying scale height. In this study, the Vary‐Chap scale height profiles are obtained based on Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) electron density profiles from 1 January 2008 to 31 December 2013 and fitted by a shape function composed of two weighted patterns representing the ion and electron contributions of lower and higher altitudes. The associated fitting parameters a and b are analyzed to reveal their temporal and spatial features and variations along with enhancement of solar activity. The prominent dependence on latitudes, longitudes, the local time, the season, and the solar cycle shown in the parameters inspires future modeling of the Vary‐Chap scale height in constructing empirical topside ionospheric models.
Ionospheric HF Heating Experiment With Frequency Ramping‐up Sweep: Approach for Artificial Ionization Layer Generation
Authors: Watkins Brenton , Kuo Spencer , Secan James , Fallen Christopher 
Published: February 2020

AbstractAn ionospheric high‐frequency (HF) heating experiment was conducted at the HAARP facility in Alaska by sweeping the heater frequency, near the third electron gyroharmonic, over a 145 kHz range with 4 min duration. A 446 MHz diagnostic radar was used to detect scattering from HF‐enhanced plasma waves corresponding to the HF‐enhanced ion lines (HFILs). Increasing frequency progressively moves the third gyroharmonic resonance layer downward, and this is evident in observations of both downgoing and upgoing HFILs dropping in height about 50 km. Artificial ionization was formed by the HF‐plasma interaction during this process and driven downward to about 150–155 km. Total electron content measurements oblique across the High Frequency Active Auroral Research Program transmit beam, above the altitude of primary ionization production, show variations that correspond to ionization production at lower heights. A theoretical interpretation of the experimental observations is presented to understand the HF‐plasma interaction process. It is shown that the double resonance condition enhances the excitation of the upper‐hybrid parametric decay instability (PDI). HF heater frequency ramping‐up sweep increases the spatial height span of the upper‐hybrid PDI generation region and the spectral width of generated upper‐hybrid waves, as well as provides a positive tuning frequency on the excited upper‐hybrid waves that keeps the continuous positive feedback on the Doppler‐shifted cyclotron harmonic resonance interaction. Resonant electrons gain energy from the upper‐hybrid waves and are generated in an extended spatial region; after a drift space, spatially distributed energetic electrons bunch together to build up a density structure.
Selective Acceleration of O+ by Drift‐Bounce Resonance in the Earth's Magnetosphere: MMS Observations
Authors: Oimatsu S. , Nosé M. , Le G. , Fuselier S. A. , Ergun R. E. , Lindqvist P.‐A. , Sormakov D. 
Published: February 2020

AbstractWe studied O+ drift‐bounce resonance using Magnetospheric Multiscale (MMS) data. A case study of an event on 17 February 2016 shows that O+ flux oscillations at ~10–30 keV occurred at MLT ~ 5 hr and L ~ 8–9 during a storm recovery phase. These flux oscillations were accompanied by a toroidal Pc5 wave and a high‐speed solar wind (~550 km/s). The azimuthal wave number (m‐number) of this Pc5 wave was found to be approximately −2. The O+/H+ flux ratio was enhanced at ~10–30 keV corresponding to the O+ flux oscillations without any clear variations of H+ fluxes, indicating the selective acceleration of O+ ions by the drift‐bounce resonance. A search for similar events in the time period from September 2015 to March 2017 yielded 12 events. These events were mainly observed in the dawn to the afternoon region at L ~ 7–12 when the solar wind speed is high, and all of them were simultaneously identified on the ground, indicating low m‐number. Correlation analysis revealed that the O+/H+ energy density ratio has the highest correlation coefficient with peak power of the electric field in the azimuthal component (Ea). This statistical result supports the selective acceleration of O+ due to the N = 2 drift‐bounce resonance.
Effects of Fluid Rheology and Pore Connectivity on Rock Permeability Based on a Network Model
Authors: Xiong Fansheng , Sun Weitao , Ba Jing , Carcione José M. 
Published: February 2020

AbstractPermeability is an important rock property in exploration geophysics. Darcy's law assumes a steady‐state regime and constant permeability. However, recent studies showed that the effects of fluid viscosity and pore geometry on permeability cannot be neglected. The periodic variation of pore fluid pressure gradient due to elastic wave propagation induces the oscillated fluid flow. We consider a Maxwell fluid in a 3‐D pore network subject to harmonic oscillations. The network is based on the Voronoi method, which provides a realistic connectivity. The permeability of polyethylene oxide and cetylpyridinium chloride and sodium salicylate solution have been simulated. The results show that permeability is constant at frequencies less than several kHz and rapidly decreases to extremely low values as frequency tends to infinite. In addition, we find that fluid mainly flows in sparse‐large pore networks at low frequencies and in dense‐small pore networks at high frequencies. The Maxwell fluid shows significant permeability peaks related to the mean coordination number, indicating that there exists an optimal network connectivity at which fluid flow is maximum. These results have been central to understand how fluid flows in natural reservoir rocks. The permeability variations versus frequency, fluid rheology, and pore connectivity provide key information of reservoir fluid properties and pore network structure. The results indicate that it is questionable whether Darcy static permeability can be applied at high frequencies.
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway
Authors: Yang Yan-Lin , Xue Meng , Jia Yi-Jie , Hu Fang , Zheng Zong-Ji , Wang Ling , Si Ze-Kun , Xue Yao-Ming 
Published: February 2020

AbstractKlotho, an antiaging protein, has been shown to play a protective role in renal tubular epithelial-mesenchymal transition (EMT) during the development of diabetic kidney disease (DKD). Long noncoding RNAs (lncRNAs) participate in the progression of EMT in many diseases. However, the effect of Klotho on lncRNAs during the development of DKD is still unknown. In this study, we found that Klotho overexpression in high-fat diet (HFD)- and streptozotocin (STZ)-induced DKD mice significantly inhibited the expression of lncRNA nuclear-enriched abundant transcript 1 (Neat1). We demonstrated that NEAT1 was significantly upregulated in both bovine serum albumin (BSA)-stimulated HK2 cells and mice with HFD- and STZ-induced diabetes. In addition, we observed that Klotho displays colocalization with NEAT1. Furthermore, overexpression of Klotho can inhibit the high expression of NEAT1 in BSA-stimulated HK2 cells, while silencing Klotho can further upregulate the expression of NEAT1. Silencing NEAT1 in HK2 cells resulted in inhibition of the EMT-related markers alpha smooth muscle actin (α-SMA) and vimentin (VIM) and the renal fibrosis-related markers transforming growth factor-β1 (TGF-β1) and connective tissue growth factor (CTGF). The effect of NEAT1 on DKD was partly mediated by regulation of the ERK1/2 signaling pathway. Finally, we found that silencing NEAT1 can reverse the activation of EMT and fibrosis caused by Klotho silencing in a manner dependent on the ERK1/2 signaling pathway. These findings reveal a new regulatory pathway by which Klotho regulates ERK1/2 signaling via NEAT1 to protect against EMT and renal fibrosis, suggesting that NEAT1 is a potential therapeutic target for DKD.
Hyperfunctioning of the right posterior superior temporal sulcus in response to neutral facial expressions presents an endophenotype of schizophrenia
Authors: Yan Zhimin , Schmidt Stephanie N. L. , Frank Josef , Witt Stephanie H. , Hass Joachim , Kirsch Peter , Mier Daniela 
Published: February 2020

AbstractDeficits in social cognition have been proposed as a marker of schizophrenia. Growing evidence suggests especially hyperfunctioning of the right posterior superior temporal sulcus (pSTS) in response to neutral social stimuli reflecting the neural correlates of social-cognitive impairments in schizophrenia. We characterized healthy participants according to schizotypy (n = 74) and the single-nucleotide polymorphism rs1344706 in ZNF804A (n = 73), as they represent risk variants for schizophrenia from the perspectives of personality traits and genetics, respectively. A social-cognitive fMRI task was applied to investigate the association of right pSTS hyperfunctioning in response to neutral face stimuli with schizotypy and rs1344706. Higher right pSTS activation in response to neutral facial expressions was found in individuals with increased positive (trend) and disorganization symptoms, as well as in carriers of the risk allele of rs1344706. In addition, a positive association between right–left pSTS connectivity and disorganization symptoms during neutral face processing was revealed. Although these findings warrant replication, we suggest that right pSTS hyperfunctioning in response to neutral facial expressions presents an endophenotype of schizophrenia. We assume that right pSTS hyperfunctioning is a vulnerability to perceive neutral social stimuli as emotionally or intentionally salient, probably contributing to the emergence of symptoms of schizophrenia.