bluuebunny/crossref_metadata_2025_split huggingface dataset:
The International Childbirth Initiative: 12 Steps to Safe and Respectful MotherBaby-Family Maternity Care
Authors: Lalonde A. , Herschderfer K. , Pascali-Bonaro D. , Hanson C. , Fuchtner C. , Visser G.H.A. 
Published: November 2019

(Int J Gynecol Obstet. 2019;146:65–73)
An initiative to guide and support quality maternity care has been launched by the International MotherBaby Childbirth Organization (IMBCO) and the International Federation of Gynecology and Obstetrics (FIGO). “The International Childbirth Initiative (ICI): 12 Steps to Safe and Respectful MotherBaby-Family Maternity Care” is a guide to implementing evidence-based maternity care with consideration of the MotherBaby dyad and family environment. The traditional medicine model has been shifted by the development of value-based care models focusing on the partnership between the provider and the care recipient. The ICI places the “MotherBaby-Family” unit as the central recipient of care, as the health of 1 member of the MotherBaby dyad has important impacts on the other. This model incorporates the practice of midwifery as a foundation of safe and respectful care.
External Cephalic Version at Term: A Cohort Study of 18 Years’ Experience
Authors: Melo P. , Georgiou E.X. , Hedditch A. , Ellaway P. , Impey L. 
Published: November 2019

(BJOG. 2019;126:493–499)
Breech presentation has been managed in part by planned cesarean section, contributing to rising cesarean section rates. External cephalic version (ECV) has been used to avoid noncephalic birth and cesarean delivery and reduce complications, including uterine scarring. Although there have been large studies documenting successful and safe ECV, these studies have left out information regarding patients with a breech presentation who did not receive ECV. This study documented the outcomes of pregnancies, both low-risk and high-risk, with a breech presentation who were referred for ECV.
Successful Fat Grafting in a Patient With Thromboangiitis Obliterans
Authors: D’Alessio Ilenia , Settembrini Alberto M. , Romagnoli Silvia , Di Luca Gabriele , Domanin Maurizio , Gabrielli Livio 
Published: November 2019

ABSTRACT
Thromboangiitis obliterans, or Buerger disease, is a rare nonatherosclerotic segmental inflammatory vasculitis that generally affects young tobacco smokers. Although no surgical treatment is available, the most effective way to halt the disease's progress is smoking cessation. In this case report, a 29-year-old smoker showed up to emergency department with gangrene of his fifth left toe and extensive plantar ulceration. After investigative angiography, he was diagnosed with Buerger disease. On November 2017, he underwent fifth left toe amputation and hyperbaric therapy. Five months after amputation, the patient was rehospitalized because of surgical wound dehiscence, wide ulceration, and pain. He was treated with lipofilling using the Coleman technique. Two weeks after the fat grafting procedure, the patient suspended pain control medication, and after 2 months, the surgical wound was almost healed. Fat grafting (lipofilling) is mostly used in plastic surgery; it offers regenerative effects, with minimal discomfort for the patient. This case report demonstrates a successful alternative use of lipofilling for this unique condition and opens up new options for use of this technique in other fields.
CE: Original Research: Experiences of Diabetes Burnout: A Qualitative Study Among People with Type 1 Diabetes
Authors: Abdoli Samereh , Hessler Danielle , Vora Amit , Smither Betsy , Stuckey Heather 
Published: November 2019

ABSTRACT

Background:
People with type 1 diabetes are at increased risk for diabetes burnout, resulting in suboptimal diabetes care and quality of life. While the existence of diabetes burnout is widely acknowledged, there is no evidence-based definition, means of measurement, or interventions to address it.

Objective:
This study was aimed at increasing our understanding of the lived experiences of diabetes burnout among adults with type 1 diabetes.

Methods:
A qualitative descriptive study was conducted with a sample of 18 adults with type 1 diabetes who reported a current or previous experience of diabetes burnout. Data were collected using in-depth interviews and analyzed using qualitative content analysis.

Results:
Four main themes were identified: mental, emotional, and physical exhaustion from having diabetes; detachment from illness identity, diabetes self-care, and support systems; contributing factors to diabetes burnout; and strategies for preventing or overcoming diabetes burnout.

Conclusion:
Although exhaustion is an entry point for diabetes burnout, the findings suggest that detachment from illness identity, diabetes self-care, and support systems form a core component. Detachment may explain poor outcomes in individuals experiencing diabetes burnout.
Dietary and Feeding Modifications for Older Adults
Authors: Batchelor-Murphy Melissa K. , Steinberg Francene M. , Young Heather M. 
Published: November 2019

This article is part of a series, Supporting Family Caregivers: No Longer Home Alone, published in collaboration with the AARP Public Policy Institute. Results of focus groups, conducted as part of the AARP Public Policy Institute's No Longer Home Alone video project, supported evidence that family caregivers aren't given the information they need to manage the complex care regimens of family members. This series of articles and accompanying videos aim to help nurses provide caregivers with the tools they need to manage their family member's health care at home.
The articles in this new installment of the series provide simple and useful instructions that nurses should reinforce with family caregivers. This article is the second of two that explain the nutritional principles nurses should consider and reinforce with caregivers. Each article includes an informational tear sheet—Information for Family Caregivers—that contains links to the instructional videos. To use this series, nurses should read the article first, so they understand how best to help family caregivers, and then encourage caregivers to watch the videos and ask questions. For additional information, see Resources for Nurses.
Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?
Authors: Abdul-Aziz Mohd H. , Roberts Jason A. 
Published: November 2019

Purpose of review
The aims of this review are to discuss the impact of extracorporeal membrane oxygenation (ECMO) on antibiotic pharmacokinetics and how this phenomenon may influence antibiotic dosing requirements in critically ill adult ECMO patients.

Recent findings
The body of literature describing antibiotic pharmacokinetic and dosing requirements during ECMO support in critically adult patients is currently scarce. However, significant development has recently been made in this research area and more clinical pharmacokinetic data have emerged to inform antibiotic dosing in these patients. Essentially, these clinical data highlight several important points that clinicians need to consider when dosing antibiotics in critically ill adult patients receiving ECMO: physicochemical properties of antibiotics can influence the degree of drug loss/sequestration in the ECMO circuit; earlier pharmacokinetic data, which were largely derived from the neonatal and paediatric population, are certainly useful but cannot be extrapolated to the critically ill adult population; modern ECMO circuitry has minimal adsorption and impact on the pharmacokinetics of most antibiotics; and pharmacokinetic changes in ECMO patients are more reflective of critical illness rather than the ECMO therapy itself.

Summary
An advanced understanding of the pharmacokinetic alterations in critically ill patients receiving ECMO is essential to provide optimal antibiotic dosing in these complex patients pending robust dosing guidelines. Antibiotic dosing in this patient population should generally align with the recommended dosing strategies for critically ill patients not on ECMO support. Performing therapeutic drug monitoring (TDM) to guide antibiotic dosing in this patient population appears useful.
Relationships Between Psychological, Social, Physical Activity, and Sleep Measures and Somatosensory Function in Individuals With Spinal Pain
Authors: Othman Rani , Dassanayake Suranga , Jayakaran Prasath , Tumilty Steve , Swain Nicola , Mani Ramakrishnan 
Published: November 2019

Objective:
Somatosensory abnormalities are linked to clinical pain outcomes in individuals with spinal pain. However, a range of factors might confound the relationship between altered somatosensory function and clinical pain outcomes. This systematic review aimed to evaluate the literature to assess the level of evidence of associations between psychological, social, physical activity, and sleep measures and somatosensory function (assessed via sensory psychophysical testing) among individuals with spinal pain.

Methods:
A comprehensive literature search was performed in 6 electronic databases from their inception to June 2018. Two reviewers independently assessed the methodological quality using a modified Quality in Prognostic Studies (QUIPS) tool and supplemented with recommendations from the Critical Appraisal and Data Extraction for the Systematic Review of Prediction Modelling Studies (CHARMS) checklist and the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. The level of evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) system. Data were pooled to evaluate the strength of the relationships of interest.

Results:
Among the 17 factors identified in the included studies, pain catastrophizing, depression, and pain-related fear have significant negative (small to fair) associations with pain thresholds. A “very low” to “moderate” quality of evidence was found for all the investigated factors. Subgroup analysis showed a smaller effect size for pain catastrophizing/fear of movement and pain thresholds in individuals with low back pain.

Conclusions:
Psychological factors are associated negatively with pain thresholds and they need to be adjusted when establishing predictive relationships between somatosensory function and pain outcomes in individuals with spinal pain.
Differences in Current Procedures for Handling of Expressed Mother's Milk in Danish Neonatal Care Units
Authors: Simonsen Marie Bendix , Hyldig Nana , Zachariassen Gitte 
Published: November 2019

Background:
Mother's own milk (MOM) is preferred when feeding preterm infants. When expressed mother's milk is stored and handled, there is a risk of bacterial contamination, decreased immunological activity, and less nutritional potential.

Purpose:
The aim of this study was to investigate current routines when handling MOM in Danish neonatal intensive care units (NICUs).

Methods:
A survey was sent to all 17 NICUs in Denmark in which current practices regarding human milk handling, storage, and preparation were evaluated. Furthermore, one question sought to establish when mother's milk was believed to be colostrum. Respondents of the survey were neonatal nurses.

Results:
All 17 units responded to the survey. Only 5 of 17 units answered that human colostrum was defined as milk from the first week after birth. Refrigerator storage time varied between 24 and 72 hours. In 6 of 17 units, parents were in charge of mixing milk and fortifier. Heating of human milk was done by using microwave ovens in 4 of 17 of the units.

Implications for Practice:
This national survey established that there is significant variability in the way mother's milk is handled. Some of the procedures performed may affect the quality of the milk. It is important to implement evidence-based practice regarding storage and handling of expressed mother's milk to ensure that the quality of the milk is the best possible alternative for all preterm infants.

Implications for Research:
Prospective studies are needed to examine the association between handling of human milk and changes in composition and nutritional potential of the milk.
Advocating for Pasteurized Donor Human Milk
Authors: Schmaltz Christopher H. , Bouchet-Horwitz Julie , Summers Lisa 
Published: November 2019

Background:
The American Academy of Pediatrics and the National Association of Neonatal Nurses recognize that federal policies fail to reimburse for the provision of pasteurized donor human milk (PDHM) to the very low birth-weight neonate, and have encouraged members to advocate for the inclusion of PDHM into their respective state Medicaid programs.

Purpose:
This article describes what occurred in New York State as advocates worked for reimbursement of PDHM reimbursement by Medicaid.

Method:
Tactics utilized in New York have been presented with an advocacy framework to illustrate the necessary strategic foresight required for productive engagement within the healthcare policy arena.

Results:
Examination of employed advocacy efforts targeted to remove known cost barriers associated with PDHM.

Implications for Practice:
Full utilization of PDHM within intensive care.

Implications for Future Research:
The necessity to engage in scholastic/evidence-based advocacy work.
Incidence, predictors, and impact of valgus reduction of traumatic intertrochanteric femoral fractures (OTA 31A1-3) treated with the helical blade system: Is anatomic reduction necessary? A retrospective case series
Authors: Kusnezov Nicholas , Prabhakar Gautham , Vanden Berge Dennis , Dabash Sherif , Thabet Ahmed M. , Abdelgawad Amr 
Published: November 2019

Background:
The purpose of this study was to describe the incidence and variables contributing to valgus distraction following cephalomedullary fixation of intertrochanteric femoral fractures with the helical blade system and to determine whether the resulting valgus reduction affected outcomes.

Methods:
We performed a retrospective case review of cephalomedullary fixation of intertrochanteric femoral fractures between 2009 and 2016. Patients treated with the helical blade system and with at least 6 mo of follow-up were included. Demographic, injury, and surgical variables were extracted from the medical record. At final follow-up complications, including implant failure, blade migration, cut-out, periprosthetic fracture, and reoperation were recorded.

Results:
Overall, 68 consecutive patients with unilateral intertrochanteric hip fractures were included. Postoperative radiographs demonstrated valgus reduction in 30 (44.1%) patients. At final follow-up, all fractures attained uneventful union. No patient experienced periprosthetic fracture or helical blade cut-out by the time of union and final follow-up. Two patients experienced postoperative infections, both requiring reoperation. Multivariate analysis revealed that only age was marginally predictive of valgus distraction (P=0.061), while fracture stability and blade position were not. Valgus reduction was not predictive of blade migration.

Conclusions:
Valgus distraction occurred in nearly half (44%) of the patients. While younger age was marginally predictive of this phenomenon, fracture stability and helical blade position were not. Furthermore, valgus reduction had no influence on the presence or degree of blade migration, cut-out, or complications. Therefore, while anatomic reduction may yield aesthetic appeal, time and effort should not be expended on direct anatomic reduction.

Level of Evidence:
Level IV.
Correlation between ACL injury and involvement of the anterolateral ligament: A retrospective study
Authors: Hegaze Adel , Khashoggi Khalid , Alsayyad Mohammed , Hafiz Rawan , Alqrache Abdulraof , Mustafa Hesham N. 
Published: November 2019

Background:
Clinical testing has demonstrated the role of the anterolateral ligament (ALL) in controlling anterolateral laxity and knee instability at high angles of flexion. Few studies have discussed the association between an anterior cruciate ligament (ACL) injury and ALL injury, specifically after residual internal rotation and a post-ACL reconstruction positive pivot-shift that could be attributed to ALL injury. The goal of this study was to assess the correlation between ALL injury and ALL injury with concomitant ACL injury using MRI.

Material and Methods:
This was a retrospective study of 246 patients with unilateral ACL knee injuries from a database that was reexamined to identify whether ALL injuries occurred in association with ACL injuries. We excluded the postoperative reconstructed cases. The charts were reviewed on the basis of the presence or absence of diagnosed ACL injury with no regard for age or sex.

Results:
Of the 246 patients with ACL injury, there were 165 (67.1%) patients with complete tears, 55 (22.4%) with partial tears, and 26 (10.6%) with sprains. There were 176 (71.5%) patients with ALL and associated ACL injuries, whereas 70 (28.5%) did not have associated ACL injuries. There was a significant statistical relationship between ACL and ALL injuries (P<0.0001).

Conclusions:
There is high incidence of ALL tears associated with ACL injuries. Clinicians should be aware of this injury and consider the possibility of simultaneous ALL and ACL repair to prevent further knee instability.

Level of Evidence:
Level IV.
Mineral and bone disorder and management in the China Dialysis Outcomes and Practice Patterns Study
Authors: Wang Jun , Bieber Brian A. , Hou Fan-Fan , Port Friedrich K. , Anand Shuchi 
Published: November 2019

Abstract

Background
Despite a growing population of patients starting hemodialysis in China, little is known about markers of mineral bone disease (MBD) and their management. We present data on prevalence and correlates of hypocalcemia, hyperphosphatemia, and secondary hyperparathyroidism from the China Dialysis Outcomes and Practice Patterns Study (DOPPS), with evaluation of whether these laboratory markers triggered changes in management.

Methods
We compared the frequency of measurement and prevalence of poor control of MBD markers in China DOPPS with other DOPPS regions. We also used generalized estimating equations to assess correlates of MBD markers, and separate models to assess predictors of vitamin D and phosphate binder prescriptions in the China DOPPS.

Results
Severe hyperphosphatemia (>7 mg/dL) and secondary hyperparathyroidism (>600 pg/mL) were common (27% and 21% prevalence, respectively); both were measured infrequently (14.9% and 3.2% of patients received monthly measurements in China). Frequency of dialysis sessions was positively associated with hyperphosphatemia; presence of residual kidney function was negatively associated with both hyperphosphatemia and secondary hyperparathyroidism. Laboratory measures indicating poor control of MBD were not associated with subsequent prescription of active vitamin D or phosphate binder.

Conclusions
There are substantial opportunities for improvement and standardization of MBD management in China. Development of country-specific guidelines may yield realistic targets and standardization of medication use accounting for availability and cost.
Stratified pain management counseling and implementation improving patient satisfaction: a prospective, pilot study
Authors: Peng Li-Hua , Min Su , Jin Ju-Ying , Wang Wen-Jian 
Published: November 2019

Abstract

Background:
Post-operative pain is unpleasant for patients and may worsen surgical recovery. Peri-operative multimodal analgesia has been used for many years; however, its efficacy still needs improvement. In the present study, a thorough peri-operative pain counseling and stratified management program based on risk assessment was implemented, with the goal of improving post-operative analgesia and patient satisfaction.

Methods:
This prospective, controlled, pilot study included 361 patients who underwent elective surgery. Of these 361 patients, 187 received peri-operative pain risk assessment and stratified analgesia and counseling (stratified analgesia group), while 174 received conventional multimodal analgesia (conventional group). The two groups were compared regarding the post-operative pain intensity, rescue analgesia administration, post-operative quality of recovery as assessed via the quality of recovery 40 questionnaire, total dosage of peri-operative opioids, analgesic satisfaction, and analgesic costs.

Results:
Compared with the conventional group, the stratified analgesia group reported decreased pain intensity during motion at 24 h post-operatively and required lower dosages of rescue analgesia (P = 0.03). The total quality of recovery 40 questionnaire score and the scores for physical wellbeing and pain were significantly better in the stratified analgesia group than the conventional group (P = 0.04); the stratified analgesia group also reported better scores for analgesic satisfaction (P = 0.03) and received lower dosages of opioids (P = 0.03). Analgesic costs were lower in the stratified analgesia group than the conventional group; the cost-effective ratio was 109 in the conventional group and 62 in the stratified analgesia group.

Conclusions:
The analgesic efficacy was improved by the implementation of stratified analgesia based on surgical pain risk assessment and counseling. This stratified analgesia protocol increased the patients’ analgesic satisfaction and improved the quality of recovery without increasing healthcare costs. The present findings may help improve the efficacy of peri-operative multimodal analgesia in clinical practice.

Clinical Trial Registry:
NCT02728973; https://clinicaltrials.gov/ct2/show/NCT02728973?term=NCT02728973&draw=2&rank=1.
Impact of Brachytherapy Boost and Dose-escalated External Beam Radiotherapy in Margin Positive Cervical Cancer Treated With Chemotherapy and Radiation
Authors: Ager Bryan J. , Torgeson Anna , Francis Samual R. , Burt Lindsay M. , Gaffney David K. , Cannon Donald M. 
Published: November 2019

Objectives:
We examined the impact of brachytherapy boost (BB) and external beam radiotherapy (EBRT) dose-escalation on overall survival (OS) for women with cervical cancer receiving postoperative chemotherapy and radiation (CRT) for a positive margin following hysterectomy.

Materials and Methods:
The National Cancer Database (NCDB) was queried from 2004 to 2015 for women with nonmetastatic squamous cell carcinoma or adenocarcinoma of the cervix who had a positive margin following hysterectomy and received postoperative CRT. Patient and treatment characteristics were assessed with multivariate logistic regression. Survival analyses were performed with univariate Cox regression and Kaplan-Meier analyses. Propensity-score weighted cohorts were generated with inverse probability of treatment weighting via generalized boosted regression modeling.

Results:
Of 630 women receiving CRT, 331 (53%) received EBRT alone and 299 (47%) received EBRT+BB. Eighty-two percent had chemotherapy initiation within 2 weeks of radiation, suggesting concurrent delivery. Median EBRT dose was 5040 cGy. Intracavitary high-dose rate was the most common BB (67%). Inclusion of BB was more likely with larger tumor sizes (odds ratio=1.03, P=0.002). Women receiving EBRT+BB had improved OS compared to EBRT alone for both unweighted (hazard ratio [HR], 0.72; P=0.020) and propensity-score weighted cohorts (HR, 0.70; P=0.017), and this finding was consistent across multiple patient subsets. EBRT dose-escalation >5040 cGy was not found to be associated with OS (unweighted HR, 1.38; P=0.065 and weighted HR, 1.16; P=0.450).

Conclusion:
The addition of BB to standard CRT improved OS for women with cervical cancer and a positive margin after hysterectomy. No consistent survival benefit was seen to EBRT dose-escalation beyond 5040 cGy.