bluuebunny/crossref_metadata_2025_split huggingface dataset:
Storage Mite Infestation of Dry-Stored Food Products and Its Relation to Human Intestinal Acariasis in the City of Minia, Egypt
Authors: Ahmed A K , Kamal A M , Mowafy N M E , Hassan E E 
Published: November 2019

AbstractInitial data on the prevalence of storage mites in dry-stored food products and estimates of the presence of mites in human stool in the city of Minia, Egypt are provided. In total, 847 samples were collected randomly from houses and retail stores between March 2017 and February 2018. In addition, 1,000 human stool samples were collected for the detection of the presence of mites. Mites were extracted from 285 of 840 (33.9%) samples, and mite contamination was found to be most prevalent in wheat flour (73.3%). In total, 11 mite species belonging to six families were identified, with the pest species Tyrophagus putrescentiae (Schrank) (Acari: Acaridae) (TP) being the most prevalent (91.2% of samples). The seasonal density distribution showed the highest storage mite density in March–April, followed by October, and the lowest in January. In addition, mites were detected in 87 (8.7%) human stool samples, with significant associations between certain occupations and some personal characteristics. Therefore, more attention needs to be paid to intestinal acariasis arising from mite infestation of dry-stored food products.
MAP: A Personalized Receptive Music Therapy Intervention to Improve the Affective Well-being of Youths Hospitalized in a Mental Health Unit
Authors: Archambault Kim , Vaugon Karole , Deumié Valérie , Brault Myriam , Perez Rocio Macabena , Peyrin Julien , Vaillancourt Guylaine , Garel Patricia 
Published: November 2019

Abstract
The MAP is an innovative receptive music therapy intervention derived from psychomusical relaxation methods that aims to foster the well-being and recovery of youths with mental health problems by providing them with an adaptive and effective music-assisted means to regulate their mood states. In this quasi-experimental pilot study, we assessed the mood-enhancing potential of participation in MAP sessions delivered by a music therapist in an in-patient mental health facility for children and adolescents. Using short standardized self-reported questionnaires, 20 participants aged 9–17 years old (M = 14, SD = 2.4), mainly girls (13 = 65%), rated their affective state immediately before and after two to four MAP sessions and a similar number of regular unit activity sessions used as comparison. This created a 2 × 2 (Time × Condition) single-group within-individual design. We analyzed pre–post session changes in affect using multilevel mixed models and found participation in MAP sessions to be associated with systematic reductions in self-reported general negative affect and state anxiety. These variations were of modest-to-large magnitude and significantly greater than those associated to participation in regular unit activities. While only a first step towards the validation of the MAP as an effective intervention to foster more adaptive and effective day-to-day mood regulation in youths with mental health problems, this study supports its specific potential to alleviate negative affects and provides a rare demonstration of the putative benefits of music therapy in a pediatric mental health inpatient context.
Where To Go? Drivers of Venezuelan Asylum Seekers
Authors: Díaz-SáNchez Juan Pablo , Bonilla-Bolaños Andrea , Obaco Moisés 
Published: November 2019

Abstract
This article reports an investigation of the drivers of Venezuelan asylum seekers—people who have left this country given the scarcity of food and medicines and the troubled actual socio-economic situation. To do so, we use data about the main countries in which Venezuelans have claimed for asylum during the period 2014–17. Using a panel-regression model, we have found that Venezuelan asylum seekers increase, on average, in countries that (i) are geographically nearby Venezuela, (ii) are less politically stable and (iii) have higher real income per capita, lower inflation rates and higher unemployment rates. Still, such a general profile of countries preferred by Venezuelan asylum seekers is nuanced by the small magnitude of the effects regarding the economic variables: it appears that Venezuelan asylum seekers hardly consider the economic situation of a country for deciding to stay. Furthermore, the empirical evidence provided by our model reflects the deterioration of Venezuela’s socio-economic aspects.
Exploring the effects of galaxy formation on matter clustering through a library of simulation power spectra
Authors: van Daalen Marcel P , McCarthy Ian G , Schaye Joop 
Published: November 2019

ABSTRACT
Upcoming weak lensing surveys require a detailed theoretical understanding of the matter power spectrum in order to derive accurate and precise cosmological parameter values. While galaxy formation is known to play an important role, its precise effects are currently unknown. We present a set of 92 matter power spectra from the OWLS, cosmo-OWLS, and BAryons and HAloes of MAssive Systems simulation suites, including different ΛCDM cosmologies, neutrino masses, subgrid prescriptions, and AGN feedback strengths. We conduct a detailed investigation of the dependence of the relative difference between the total matter power spectra in hydrodynamical and collisionless simulations on the effectiveness of stellar and AGN feedback, cosmology, and redshift. The strength of AGN feedback can greatly affect the power on a range of scales, while a lack of stellar feedback can greatly increase the effectiveness of AGN feedback on large scales. We also examine differences in the initial conditions of hydrodynamic and N-body simulations that can lead to an $\sim 1{{\ \rm per\ cent}}$ discrepancy in the large-scale power, and furthermore show our results to be insensitive to cosmic variance. We present an empirical model capable of predicting the effect of galaxy formation on the matter power spectrum at z = 0 to within $1{{\ \rm per\ cent}}$ for $k\lt 1\, h\, \mathrm{Mpc}^{-1}$, given only the mean baryon fraction in galaxy groups. Differences in group baryon fractions can also explain the quantitative disagreement between predictions from the literature. All total and dark matter only power spectra in this library will be made publicly available at powerlib.strw.leidenuniv.nl.
Exploring the high-mass end of the stellar mass function of star-forming galaxies at cosmic noon
Authors: Sherman Sydney , Jogee Shardha , Florez Jonathan , Stevans Matthew L , Kawinwanichakij Lalitwadee , Wold Isak , Finkelstein Steven L , Papovich Casey , Acquaviva Viviana , Ciardullo Robin , Gronwall Caryl , Escalante Zacharias 
Published: November 2019

ABSTRACT
We present the high-mass end of the galaxy stellar mass function using the largest sample to date (5352) of star-forming galaxies with M⋆ &gt; 1011 M⊙ at cosmic noon, 1.5 &lt; z &lt; 3.5. This sample is uniformly selected across 17.2 deg2 (∼0.44 Gpc3 comoving volume from 1.5 &lt; z &lt; 3.5), mitigating the effects of cosmic variance and encompassing a wide range of environments. This area, a factor of 10 larger than previous studies, provides robust statistics at the high-mass end. Using multiwavelength data in the Spitzer/HETDEX Exploratory Large Area (SHELA) footprint, we find that the SHELA footprint star-forming galaxy stellar mass function is steeply declining at the high-mass end probing values as high as ∼10−4 Mpc3 dex−1 and as low as ∼5 × 10−8 Mpc3 dex−1 across a stellar mass range of log(M⋆/M⊙) ∼ 11–12. We compare our empirical star-forming galaxy stellar mass function at the high-mass end to three types of numerical models: hydrodynamical models from IllustrisTNG, abundance matching from the UniverseMachine, and three different semi-analytical models (SAMs; SAG, SAGE, GALACTICUS). At redshifts 1.5 &lt; z &lt; 3.5, we find that results from IllustrisTNG and abundance matching models agree within a factor of ∼2–10, however the three SAMs strongly underestimate (up to a factor of 1000) the number density of massive galaxies. We discuss the implications of these results for our understanding of galaxy evolution.
Understanding extreme quasar optical variability with CRTS – II. Changing-state quasars
Authors: Graham Matthew J , Ross Nicholas P , Stern Daniel , Drake Andrew J , McKernan Barry , Ford K E Saavik , Djorgovski S G , Mahabal Ashish A , Glikman Eilat , Larson Steve , Christensen Eric 
Published: November 2019

ABSTRACT
We present the results of a systematic search for quasars in the Catalina Real-time Transient Survey exhibiting both strong photometric variability and spectroscopic variability over a decadal baseline. We identify 111 sources with specific patterns of optical and mid-infrared photometric behaviour and a defined spectroscopic change. These ‘changing-state’ quasars (CSQs) form a higher luminosity sample to complement existing sets of ‘changing-look’ AGNs and quasars in the literature. The CSQs (by selection) exhibit larger photometric variability than the changing-look quasars (CLQs). The spectroscopic variability is marginally stronger in the CSQs than CLQs as defined by the change in H β/[$\rm {O \,\rm {\small {III}}}$] ratio. We find 48 sources with declining H β flux and 63 sources with increasing H β flux, and discover 8 sources with $z$ &gt; 0.8, further extending the redshift arm. Our CSQ sample compares to the literature CLQ objects in similar distributions of H β flux ratios and differential Eddington ratios between high (bright) and low (dim) states. Taken as a whole, we find that this population of extreme varying quasars is associated with changes in the Eddington ratio and the time-scales imply cooling/heating fronts propagating through the disc.
No evidence of a sudden change of spectral appearance or magnetic field strength of the O9.7V star HD 54879
Authors: Wade G A , Bagnulo S , Keszthelyi Z , Folsom C P , Alecian E , Castro N , David-Uraz A , Fossati L , Petit V , Shultz M E , Sikora J 
Published: November 2019

ABSTRACT
It was recently claimed that the magnetic O-type star HD 54879 exhibits important radial velocity variability indicative of its presence in a spectroscopic binary. More remarkably, it was furthermore reported that the star underwent a short, sudden variation in spectral type and magnetic field. In this letter, we examine new Narval and ESPaDOnS data of this star in addition to the previously published FORS2 data and conclude that both the reported velocity variations and the sudden spectral and magnetic changes are spurious.
Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism
Authors: Lezzerini Marco , Penzo Marianna , O’Donohue Marie-Françoise , Marques dos Santos Vieira Carolina , Saby Manon , Elfrink Hyung L , Diets Illja J , Hesse Anne-Marie , Couté Yohann , Gastou Marc , Nin-Velez Alexandra , Nikkels Peter G J , Olson Alexandra N , Zonneveld-Huijssoon Evelien , Jongmans Marjolijn C J , Zhang GuangJun , van Weeghel Michel , Houtkooper Riekelt H , Wlodarski Marcin W , Kuiper Roland P , Bierings Marc B , van der Werff ten Bosch Jutte , Leblanc Thierry , Montanaro Lorenzo , Dinman Jonathan D , Da Costa Lydie , Gleizes Pierre-Emmanuel , MacInnes Alyson W 
Published: November 2019

Abstract
Variants in ribosomal protein (RP) genes drive Diamond-Blackfan anemia (DBA), a bone marrow failure syndrome that can also predispose individuals to cancer. Inherited and sporadic RP gene variants are also linked to a variety of phenotypes, including malignancy, in individuals with no anemia. Here we report an individual diagnosed with DBA carrying a variant in the 5′UTR of RPL9 (uL6). Additionally, we report two individuals from a family with multiple cancer incidences carrying a RPL9 missense variant. Analysis of cells from these individuals reveals that despite the variants both driving pre-rRNA processing defects and 80S monosome reduction, the downstream effects are remarkably different. Cells carrying the 5′UTR variant stabilize TP53 and impair the growth and differentiation of erythroid cells. In contrast, ribosomes incorporating the missense variant erroneously read through UAG and UGA stop codons of mRNAs. Metabolic profiles of cells carrying the 5′UTR variant reveal an increased metabolism of amino acids and a switch from glycolysis to gluconeogenesis while those of cells carrying the missense variant reveal a depletion of nucleotide pools. These findings indicate that variants in the same RP gene can drive similar ribosome biogenesis defects yet still have markedly different downstream consequences and clinical impacts.
Severe alcohol intoxication among Canadian Youth: A 2-year surveillance study
Authors: Acker Amy , Norris Mark L , Coo Helen , Santos Alexandre , Allain Dominic , Dow Kimberly 
Published: November 2019

Abstract

Purpose
To obtain data on Canadian youth, aged 11 to 15 years, presenting to paediatric emergency departments, with severe alcohol intoxication and to describe demographics, presentations to hospital, concurrent substance use, comorbidities, and short-term outcomes of admission to emergency departments.

Methods
Between March 2013 and February 2015, through the established methodology of the Canadian Paediatric Surveillance Program, Canadian paediatricians and paediatric subspecialists were surveyed monthly to identify cases of young adolescents presenting to paediatric emergency departments across Canada with severe alcohol intoxication. Those that identified cases were subsequently sent a detailed questionnaire. The detailed questionnaires were then screened to ensure the reported cases met the study’s inclusion criteria.

Results
A total of 39 cases (18 females and 21 males) were included in the final analysis. Overall, results indicate over 90% of presenting youth had consumed spirits, 39% had concurrent substance use and 46% experienced serious medical morbidity. Almost two-thirds of youth were admitted to hospital for a period ranging from 10 hours to 5 days; 12 youth required intubation. Follow-up referrals were provided to two-thirds of youth, with variable supports given. No statistically significant differences between sexes were noted for blood alcohol level or concurrent substance use.

Conclusion
Although rates of alcohol use in adolescents have been steadily decreasing, results from this surveillance study suggest that severe intoxication arising from the use of alcohol alone, and with concurrent substance use, results in significant immediate health consequences in young adolescents. Results from this study also highlight characteristics of patients, initial treatments and initial referrals across Canadian paediatric healthcare facilities, the results of which highlight variability and may aid in the guidance of a future longitudinal study, prevention strategies, and public health messaging.
Employment in the neighborhoods of Barcelona: health effects of an active labor market program in Southern Europe
Authors: González-Marín Patricia , Puig-Barrachina Vanessa , Bartoll Xavier , Cortés-Franch Imma , Malmusi Davide , Clotet Eva , Cardona Africa , Artazcoz Lucía , Borrell Carme 
Published: November 2019

ABSTRACT

Background
The aim of this study was to analyze the changes in self-perceived health status and mental health among participants in an active labour market policy (ALMP) of Barcelona, and to assess whether the results differed according to the participants’ social characteristics and their program trajectories.

Methods
A pre–post intervention study was designed, including unemployed people participating in a return-to-work ALMP in 13 deprived neighborhoods of Barcelona; using one survey upon entering the program (pre), and another 1 year later (post). We assessed the prevalence of poor self-perceived health status and poor mental health (Goldberg-12 questionnaire) in both periods of time. We fit five Poisson regression models using generalized estimating equations (GEE) to measure changes in self-perceived health and mental health between pre- and post-intervention.

Results
About 696 individuals (48% women) participated in the study, mainly manual workers. In both sexes, mental health improved (prevalence ratio [PR]—comparing post- and pre-periods for women: 0.49, 95% confidence interval [CI]: 0.39–0.61 and men: PR: 0.41, 95% CI: 0.32–0.53), whereas self-perceived health status remained stable or worsened. Men who remained unemployed reported poorer self-perceived health status, while no such association was observed among women.

Conclusions
This study shows a mental health improvement among male and female participants.
Validity of the Cold Pressor Test and Pain Sensitivity Questionnaire via online self-administration
Authors: McIntyre Matthew H. ,   23andMe Research Team, Kless Achim , Hein Peter , Field Mark , Tung Joyce Y. 
Published: November 2019

AbstractTo determine the feasibility of complex home-based phenotyping, 1,876 research participants from the customer base of 23andMe participated in an online version of a Pain Sensitivity Questionnaire (PSQ) as well as a cold pressor test (CPT) which is used in clinical assessments of pain. Overall our online version of the PSQ performed similarly to the original pen-and-paper version. Construct validity of the PSQ total was demonstrated by internal consistency and consistent discrimination between more and less painful items. Criterion validity was demonstrated by correlation with pain sensitivity as measured by the cold pressor test. Within the same cohort we performed a cold pressor test using a layperson description and household equipment. Comparison with published reports from controlled studies revealed similar distributions of cold pain tolerance times (i.e., time elapsed before removing the hand from the water). Of those who elected to participate in the CPT, a large majority of participants did not report issues with the test procedure or noncompliance to the instructions (97%). We confirmed a large sex difference in CPT thresholds in line with published data, such that women removed their hands from the water at a median of 54.2 seconds, with men lasting for a median time of 82.7 seconds (Kruskal-Wallis statistic, p < 0.0001), but other factors like age or current pain treatment were at most weakly associated, and inconsistently between men and women. We introduce a new paradigm for performing pain testing, called testing@home, that, in the case of cold nociception, showed comparable results to studies conducted under controlled conditions and supervision of a health care professional.SummaryResearch paradigms employing home-based phenotyping are feasible, with both questionnaires and self-administration of a well-established experimental human pain model yielding similar results compared to controlled settings.
Step-downs reduce workers’ compensation payments to encourage return to work. Are they effective?
Authors: Lane Tyler J , Sheehan Luke R , Gray Shannon E , Beck Dianne , Collie Alex 
Published: November 2019

AbstractObjectiveTo determine whether step-downs, which cut the rate of compensation paid to injured workers after they have been on benefits for several months, are effective as a return to work incentive.MethodsWe aggregated administrative claims data from seven Australian workers’ compensation systems to calculate weekly scheme exit rates, a proxy for return to work. Jurisdictions were further subdivided into four injury subgroups: fractures, musculoskeletal, mental health, and other trauma. The effect of step-downs on scheme exit was tested using a regression discontinuity design. Results were pooled into meta-analyses to calculate combined effects and the proportion of variance attributable to heterogeneity.ResultsThe combined effect of step-downs was a 0.86 percentage point (95% CI -1.45 to -0.27) reduction in the exit rate, with significant heterogeneity between jurisdictions (I2= 68%,p= .003). Neither timing nor magnitude of step-downs was a significant moderator of effects. Within injury subgroups, only fractures had a significant combined effect (-0.84, 95% CI -1.61 to -0.07). Sensitivity analysis indicated potential effects within mental health and musculoskeletal conditions as well.ConclusionsThe results suggest some workers’ compensation recipients anticipate step-downs and exit the system early to avoid the reduction in income. However, the effects were small and suggest step-downs have marginal practical significance. We conclude that step-downs are generally ineffective as a return to work policy initiative.Key messages1.What is already known about this subject?A number of workers’ compensation systems around the world reduce payments to injured workers after they have been in the system for several months. In Australia, where each state, territory, and Commonwealth system employs step-downs, the stated policy objective is to increase the rate of return to work through financial incentives. However, there is little empirical evidence to either support or reject this claim.2.What are the new findings?The rate at which claimants exited workers’ compensation systems increased ahead of step-downs taking effect, suggesting an anticipatory effect. However, the effect was relatively small, changing the exit rate by less than a percentage point overall, with substantial heterogeneity between systems.3.How might this impact on policy or clinical practice in the foreseeable future?While statistically significant, the findings suggest that step-downs provide workers’ compensation claimants little incentive to return to work. Policymakers may need to reconsider step-downs as a component of scheme design, or justify them according to their original purpose, which was to save costs.
Limited Capacity for Ipsilateral Secondary Motor Areas to Support Hand Function Post-Stroke
Authors: Wilkins Kevin B. , Yao Jun , Owen Meriel , Karbasforoushan Haleh , Carmona Carolina , Dewald Julius P.A. 
Published: November 2019

AbstractRecent findings have shown connections of ipsilateral cortico-reticulospinal tract (CRST), predominantly originating from secondary motor areas, to not only proximal but also distal portions of the arm. In unilateral stroke, CRST from the ipsilateral side is intact and thus has been proposed as a possible backup system for post-stroke rehabilitation even for the hand. We argue that although CRST from ipsilateral secondary motor areas can provide control for proximal joints, it is insufficient to control either hand or coordinated shoulder and hand movements due to its extensive branching compared to contralateral corticospinal tract. To address this issue, we combined MRI, high-density EEG, and robotics in 17 individuals with severe chronic hemiparetic stroke and 12 age-matched controls. We tested for changes in structural morphometry of the sensorimotor cortex and found that individuals with stroke demonstrated higher gray matter density in secondary motor areas ipsilateral to the paretic arm compared to controls. We then measured cortical activity while participants attempted to generate hand opening either supported on a table or while lifting against a shoulder abduction load. The addition of shoulder abduction during hand opening increased reliance on ipsilateral secondary motor areas in stroke, but not controls. Crucially, increased use of ipsilateral secondary motor areas was associated with decreased hand opening ability while lifting the arm due to involuntary coupling between the shoulder and wrist/finger flexors. Together, this evidence implicates a compensatory role for ipsilateral (i.e., contralesional) secondary motor areas post-stroke, but with limited capacity to support hand function.