bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efek Imunostimulator Kubis (Brassica Oleracea Var. Capitata Alba) Terhadap Titer Imunoglobulin G (Ig G) Pada Kelinci Yang Diinduksi Dengan Sel Darah Merah Domba
Authors: Inayati Nurul , Fihiruddin Fihiruddin , Getas I Wayan 
Published: November 2020

Kubis (Brassica aloracae var.capitata alba) adalah salah satu sayuran yang berpotensi sebagai imunostimulator. Kubis banyak megandung nutrien yang mempunyai nutrisi tinggi seperti vitamin, mineral, dietary fiber, glukosinolates, polyphenol dan phenolic acid. Disamping itu juga kubis mengandung peptida yang berperan sebagai imunoglobulin production stimulating factor (IPSF) sehingga dapat berfungsi sebagai imunostimulator yang akan dapat meningkatkan sistem imun tubuh dengan cara merangsang peningkatan sistem fagositik dan produksi interleukin 5. Penelitian ini merupakan penelitian ekprimental dengan desain statistic group comparation yang bertujuan mengetahui pengaruh pemberian kubis (Brassica oleracea capitata alba) untuk meningkatkan pembentukan immunoglobulin G (IgG) pada kelinci yang diinduksi dengan sel darah merah domba 2 %. Hewan coba yang digunakan dikelompokkan menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Hewan coba yang akan digunakan adalah kelinci dengan berat 700 – 800 gr sebanyak 20 ekor yang akan dibagi menjadi dua kelompok yaitu kelompok perlakuan dan kontrol. Metode pemeriksaan yang digunakan adalah dengan uji heamaglutinasi dengan mengamati terjadinya aglutinasi antara serum yang diambil dari darah kelinci dengan sel darah merah domba (SDMD) 2 %. Rata-rata titer Imunoglobulin G (IgG) pada kelompok perlakuan dan kelompok kontrol masing-masing adalah 2.26 µl/ml dan 1.62 µl/ml. Hasil uji statistik dengan paired t test dengan tingkat kepercayaan 0,95 % menunjukkan bahwa terdapat perbedaan yang signifikan ( p < 0,05) antara kelompok perlakuan dan kelompok kontrol yaitu dengan nilai signifikannya adalah 0,043.
Kandungan Protein Roti Tawar Dengan Subtitusi Tepung Ikan Gabus (Channa Striata)
Authors: Adam Adriyani , Syafii Firdaus , Saiful Saiful 
Published: November 2020

Background : Malnutrition problem is still the top priority in Indonesia and one of focuses in the Medium Term Development Plan (RPJMN) for 2020-2024. Riskesdas 2018, show the percentage of nutritional status of stunting under five age in Indonesia 2018 was 25.7%, in West Sulawesi Province was the second highest contributor for stunting children in Indonesia with prevalence 41.8%. One of the preventive efforts that can be done is through the development of food products. In this study, the development of white bread with the substitution of Channa Striata fish flour was expected to enrich the nutritional content of bread, especially protein. In this study, using Channa Striata fish because it has a higher protein content than other foodstuffs known as sources of protein such as eggs, chicken and beef. Apart from protein, Channa Striata fish also has a high albumin content which can be used in wound healing. This aims of this study to determine the protein content of white bread with the substitution of Channa Striata fish meal by 5% and 10% Methods : This type of research is an experimental study to determine the protein content in white bread with the substitution of Channa Striata fish meal by 5% and 10%. The analytical method used to assess protein content is the kjeidhal method, which is a simple method for determining total nitrogen in amino acids, proteins, and nitrogen-containing compounds. The test was carried out at Health Laboratory South Sulawesi. Results : The results showed that the protein content of white bread with a substitution of 5% was 9.03 grams, and a substitution of 10% was 10.38 grams. Conclusion : The conclusion of this study was even more substitution of Channa Striata fish flour used, will increase protein content in the white bread.
Pentingnya Komunikasi Orang Tua-Anak terhadap Self Efficacy Anak Usia Sekolah
Authors: Junalia Elly , Setiawan Agus , Fitriani Poppy 
Published: November 2020

Self efficacy anak usia sekolah merupakan keyakinan kemampuan diri dalam hal akademik, sosial, dan emosional yang dimiliki oleh anak usia sekolah serta berpengaruh terhadap perilaku anak usia sekolah. Self efficacy merupakan faktor penting dalam perkembangan psikologis anak. Pembentukan dan perkembangan self efficacy anak usia sekolah didukung oleh peran orang tua melalui komunikasi antara orang tua dan anak. Penelitian ini bertujuan untuk mengetahui hubungan antara komunikasi orang tua dan anak dengan self efficacy pada anak usia sekolah. Penelitian ini menggunakan desain penelitian cross sectional. Pengambilan sampel dengan teknik cluster sampling. Responden penelitian ini adalah 152 siswa kelas 4,5, dan 6 SD Negeri Kreo 5 Tangerang yang berumur 10 - 12 tahun. Instrumen yang digunakan kuesioner komunikasi orang tua dan anak dan kuesioner self efficacy anak usia sekolah. Hasil penelitian menunjukkan ada hubungan antara komunikasi orang tua dan anak dengan self efficacy anak usia sekolah (p value < 0,001, α 0,05). Semakin efektif komunikasi antara orang tua dan anak maka semakin tinggi self efficacy yang dimiliki anak usia sekolah, sebaliknya semakin tidak efektif komunikasi antara orang tua dan anak maka semakin rendah self efficacy yang dimiliki anak usia sekolah. Dengan demikian, komunikasi antara orang tua dan anak penting dalam pembentukan dan perkembangan self efficacy anak usia sekolah.
Perbandingan Efektivitas Pendidikan Kesehatan Dengan Media Leaflet Dan Audio Visual Dalam Meningkatkan Pengetahuan Remaja Tentang Pemeriksaan Payudara Sendiri (SADARI)
Authors: Janah Niluh Miftahul , Timiyatun Endar 
Published: November 2020

ABSTRAK Kanker payudara adalah penyakit akibat pertumbuhan tidak normal dari sel-sel jaringan tubuh menjadi sel kanker. Sel-sel yang terus menerus tumbuh menjadi benjolan disebut dengan tumor. Tumor ganas mempunyai sifat yang khas, yaitu dapat menyebar luas ke bagian lain di seluruh tubuh untuk berkembang menjadi tumor yang baru. Sel kanker dapat menyebar kebagian tubuh lainnya. Masalah utama terjadinya kanker payudara adalah ketidakteraturan dan jarang sekali melakukan SADARI dengan benar. Sikap remaja yang tidak baik dapat mempengaruhi perilaku dalam melakukan SADARI. Mengetahui perbandingan efektifitas pendidikan kesehatan dengan media leaflet dan audiovisual dalam meningkatkan pengetahuan remaja tentang SADARI di SMA Negeri 2 Banguntapan. Jenis penelitian yang digunakan adalah pra exsperiment one group pretest and postest, rancangan ini juga tidak ada kelompok pembanding (kontrol). Sampel berjumlah 40 responden, dengan pembagian 20 responden kelompok leaflet dan 20 responden kelompok audiovisual. Populasi dalam penelitian ini adalah siswi di SMA Negeri 2 Banguntapan. Uji statistik yang di gunakan pada penelitian ini adalah uji wilcoxon. Hasil penelitian didapatkan ada pengaruh pendidikan kesehatan melalui media leaflet dengan nilai (p=0,000) dan pendidikan kesehatan melalui media audiovisual (p=0,000). Dan menggunakan uji mann-whitney didapatkan (p=0,001) didapatkan hasil nilai mean untuk leaflet 14,40 dan untuk audiovisual sebesar 26,60 yang artinya bahwa pendidikan kesehatan menggunakan media audiovisual lebih efektif dari pada menggunakan media leaflet. Ada perbedaan efektivitas pendidikan kesehatan dengan media leaflet dan audiovisual dalam meningkatkan pengetahuan tentang SADARI di SMA Negeri 2 Banguntapan.
PENGARUH PIJAT BAYI TERHADAP PERKEMBANGAN PADA BAYI USIA 3 SAMPAI 6 BULAN DI KELURAHAN MANDALIKA WILAYAH KERJA PUSKESMAS CAKRANEGARA TAHUN 2019
Authors: Mariana Junita , Sopiatun Rita 
Published: November 2020

Masalah pertumbuhan dan perkembangan masih menjadi permasalahan kesehatan anak pada saat ini. Menurut WHO tahun 2013 mencatat bahwa setiap tahun lebih dari 200 juta anak mengalami gangguan pertumbuhan dan perkembangan.Data nasional Menurut Kemenkes RI bahwa pada tahun 2010, sebesar 11,5 % anak balita di Indonesia mengalami kelainan pertumbuhan dan perkembangan sedangkan dari data Riskesdas tahun 2018 menunjukkan total indeks perkembangan anak di Indonesia mencakup 88,3 % . Penelitian ini bertujuan untuk mengetahui pengaruh pijat bayi terhadap Perkembangan pada bayi usia 3 sampai 6 bulan di Kelurahan Mandalika wilayah kerja Puskesmas Cakranegara Adapun metode penelitian yang digunakan dalam proposal ini adalah quasi eksperimen dengan rancangan non equivalent control group dan teknik pengambilan sampel yaitu purposive sampling. Populasi dalam penelitian ini adalah bayi yang berusia 3-6 bulan yang memiliki perkembangan meragukan atau menyimpang, dengan jumlah sampel 30 bayi. Penelitian ini dilaksanakan pada bulan april 2019.Hasil Penelitian menunjukkan bahwa setelah dilakukan uji mann whitney didapatkan hasil analisis pengaruh pijat bayi terhadap perkembangan pada kelompok eksperimen dan kelompok control yaotu p value = 0,000 < α (0,05) menunjukkan bahwa terdapat perbedaan antara kelompok eksperimen dan kelompok kontrol terhadap perkembangan bayi. Ada pengaruh pijat bayi terhadap perkembangan bayi pada usia 3-6 bulan.The problem of growth and development is still a child health problem at this time. According to the 2013 WHO noted that every year more than 200 million children experience growth and development disorders. National data According to the Indonesian Ministry of Health that in 2010, 11.5% of children under five in Indonesia experienced abnormalities in growth and development while from the Riskesdas in 2018 showed the total child development index in Indonesia includes 88.3%. the purpose of this study is to know the Influence of Baby Message for Baby Development at the ages 3 – 6 months on Working Region of Cakranegara Health Center in 2019. The research method used in this proposal was quasi-experimental with a non equivalent control group design and the sampling technique was purposive sampling. The population in this study were babies aged 3-6 months who had dubious or deviant development, with a sample of 30 babies. This research was conducted in April 2019. The result of this study is after the Mann Whitney test, the results of the analysis of the effect of infant massage on the development in the experimental group and the control group p value = 0.000 <α (0.05) showed that there were differences between the experimental group and the control group on baby development, so there is an effect of baby massage on the development of babies at the age of 3-6 months.
PERBEDAAN ANTARA KOMBINASI MASSAGE WOOLWICH DAN MASSAGE ROLLING DENGAN TEKNIK MARMET TERHADAP PRODUKSI ASI PADA IBU NIFAS DI WILAYAH KERJA PUSKESMAS KARANG PULE
Authors: Nurfija Juninda , Murni Ni Nengah Arini 
Published: November 2020

ASI eksklusif merupakan salah satu program yang cukup sulit dikembangkan karena berkaitan dengan berbagai permasalahan sosial di masyarakat. Untuk mencegah dan menangani masalah laktasi tersebut, maka dimungkinkan sebuah intervensi yaitu Kombinasi Masssage Woolwich dan Massage Rolling serta Tekhnik Marmet. Dilakukannya penelitian ini yaitu guna mengetahui adanya perbedaan Kombinasi Masssage Woolwich dan Massage Rolling dengan Tekhnik Marmet terhadap produksi ASI ibu nifas di wilayah kerja Puskesmas Karang Pule. Penelitian ini menggunakan rancangan penelitian Quasi Eksperiment dengan menggunakan rancangan post test only design with control group. Populasi penelitian ini adalah seluruh ibu nifas di wilayah kerja Puskesmas Karang Pule, sampel diambil dengan consecutive sampling dengan jumlah 34 orang. Analisis data menggunakan Independent T- test untuk mengetahui adanya perbedaan produksi ASI antara dua kelompok intervensi. Produksi ASI pada kelompok intervensi kombinasi massage woolwich dan massage rolling didapatkan rata-rata yaitu 29,12 cc. Sementara produksi ASI pada kelompok dengan tehnik marmet didapatkan rata-rata yaitu 22,35 cc. Uji statistik yang digunakan adalah Independent T-test didapatkan hasil nilai t sebesar 2,617 dan signifikansi (p) 0,013 < 0,05. Ada Perbedaan antara kombinasi massage woolwich dan massage rolling dengan tekhnik marmet terhadap produksi ASI ibu nifas di wilayah kerja Puskesmas Karang Pule Tahun 2019. Exclusive breastfeeding is one program that is quite difficult to develop because it is related to various social problems in the community. To prevent and deal with the problem of lactation, an intervention is possible, namely a combination of wolwich massage, Rolling Massage and Marmet Technique. This research is conducted to find the different of woolwich massage combination and rolling massage with marmet technique to milk production of postpartum mother in the working area of Karang Pule Public Health Center in 2019. This study used a Quasi Experiment design using a post test only design with control group. The population was all postpartum mothers at working area of Karang Pule Public Health Center, samples were taken with consecutive sampling with a total of 34 people. Data analysis used the Independent T-test to determine the differences in ASI production between the two intervention groups. Breast milk production in the intervention group combined of woolwich massage and rolling massage obtained an average of 29.12 cc. While breast milk production in the group with the marmet technique was obtained an average of 22.35 cc. The statistical test used is the Independent T-test, the results of the t value are 2.617 and the significance (p) is 0.013 <0.05. There is a difference between the combination of massage woolwich and rolling massage with marmet techniques on the production of breast milk for postpartum mothers in the work area of the Karang Pule Health Center in 2019.
Editorial
Authors: Chakraborty Rhyddhi 
Published: November 2020

Cambridge online dictionary offers the meaning of the noun term “environment” as the air, water, and land in or on which humans, animals, and plants reside1. The environment can also be mixture of factors that influence both organic and inorganic ecosystems and their shared co-existence. This co-existence is the last idea that is given significance in the sophisticated and busy life styles of the modern day. In other words, in our own attitudes lies a large portion of causal conditions for outward environmental disruptions and imbalances. The challenges we face globally have their origin in local settings, the threats we face at the surface level of our location have their origins at 'deep level' in our very own way of living, in the very way of our behaviour towards others. With this absence of senses, species of human beings not only put themselves at risk, but also put other species of life in danger all over the world. It can be said that the ecological sufferings what we are experiencing today are seemed to have deep roots in anthropocentric views about the dominion of humans on earth. Without major societal changes, including changes in the habits of human beings, these exploitative, consumerist practices cannot be resolved 2.
The papers in this issue on Environmental Ethics emphasize the need of the sense of morality towards the surrounding environment.
Um Experimento Inicial sobre Associações entre os Crimes Ocorridos no Brasil
Authors: Gomes Wesckley Faria , Colaço Júnior Methanias , Prado Kleber Henrique de Jesus 
Published: November 2020

Contexto: A criminalidade tem sido um problema ao redor do mundo, causando danos às sociedades. Educação, pobreza, emprego e clima são alguns fatores que afetam a taxa de criminalidade, levando as autoridades a gastar, anualmente, milhões com ações de combate à violência e planos estratégicos de prevenção e redução da criminalidade. Objetivo: Aplicar conceitos de Data Science para análise de dados governamentais relacionados a crimes no Brasil. Método: Uso de mineração de dados, especificamente regras de associação (RA), em um experimento controlado, para detecção de padrões entre os tipos de crimes, como também entre os tipos de crime e meses do ano. Resultados: No contexto das associações entre crimes, os estados com regras mais interessantes foram: Bahia, com 15 associações, São Paulo, com 12, Goiás, 11, e Paraná, com 9. Destaque para a associação “Latrocínio Roubo de Carga”, encontrada para o Estado da Bahia, a qual atingiu uma confiança de 99% (0.99). Já no âmbito das associações entre crimes e meses do ano, avultaram-se Paraíba, com 2 associações, Maranhão, Rondônia e São Paulo, com 1 associação cada. Destaque para regra “Dezembro Roubo de Veículo”, encontrada para o Estado de São Paulo, que alcançou uma confiança de 84% (0,84). Conclusão: Os resultados expostos nesta pesquisa auxiliam analistas criminais no processo de tomada de decisão para prevenção e redução da criminalidade no país, uma vez que podem permitir a inibição de crimes que são antecedentes de outras ocorrências dentro do mesmo estado ou de crimes que ocorrem num mesmo período.
Search for weakly interacting massive dark matter particles: state of the art and prospects
Authors: Aleksandrov A B , Dashkina A B , Konovalova N S , Okat’eva N M , Polukhina N G , Starkov N I , Tioukov V E , Chernyavsky M M , Shchedrina T V 
Published: November 2020

Abstract
Determining the nature of dark matter (DM) is one of the most important challenges of modern experimental physics. This article overviews the major arguments confirming the existence of DM, gives the latest classifications of DM particles, identifies possible candidates for their role, and discusses the most significant DM particle search experiments conducted and under development. The article mainly aims to give an idea of diverse experimental methods of and approaches to registering DM particles, as well as of the currently available results of the search for them, which open new prospects in DM studies and contribute to solving topical problems in New Physics.
The Current Landscape of Clinical Studies Focusing on Thyroid Cancer: A Comprehensive Analysis of Study Characteristics and Their Publication Status
Authors: Liu Yihao , Li Bin , Zheng Qiuyi , Xu Jia , Li Jie , Lai Fenghua , Lin Bo , Peng Sui , Lv Weiming , Xiao Haipeng 
Published: November 2020

BackgroundA better understanding of the current characteristics of clinical trials on thyroid cancer (TC) is important to improve trial designs and identify neglected areas of research. However, there is a lack of a thorough understanding of the clinical studies on TC. Therefore, this study aimed to present a comprehensive overview of clinical trials on TC based on the ClinicalTrials.gov database and evaluate their publication status.MethodsWe searched for TC-related clinical studies registered in the ClinicalTrials.gov database before December 2018 by using the keyword “thyroid cancer” and assessed the characteristics of the included trials. We searched the publication status of primary completed studies in PubMed and Google Scholar.ResultsA total of 450 studies were identified for analysis, including 333 (74.0%) interventional studies and 117 (26.0%) observational studies. Interventional studies about TC were commonly non-randomized (67.6%), single-arm (55.6%), single-center (76.3%), and early-phase (60.0%) trials. The major category for which studies were performed was for target drug-related therapy (53.6%). In addition, 57.0% of the primary completed interventional studies were published. The published studies were more commonly primary completed studies after 2010 and used randomization and were less commonly designed as single-arm studies and were conducted in the USA/Canada, compared to non-published studies (P &lt; 0.05 for all). The median time from primary completion to publication was 46.5 months, and the time decreased to 36.5 months after 2010. Studies conducted in the USA/Canada [odds ratio (OR) = 9.43, P = 0.020] and multi-center studies (OR = 6.55, P = 0.021) significantly increased the potential of publication in high-impact journals.ConclusionsHigh-quality, randomized phase 3 trials regarding TC are still insufficient. Therefore, more efforts are needed to improve the treatment of poor prognostic TC and timely publication.
Differentiating Responders and Non-responders to rTMS Treatment for Disorder of Consciousness Using EEG After-Effects
Authors: He Renhong , Fan Jianzhong , Wang Huijuan , Zhong Yuhua , Ma Jianhua 
Published: November 2020

Background: It is controversial whether repetitive transcranial magnetic stimulation (rTMS) has potential benefits in improving the awareness of patients with disorder of consciousness (DOC). We hypothesized that rTMS could improve consciousness only in DOC patients who have measurable brain responses to rTMS.Objective: In this study, we aimed to investigate the EEG after-effects induced by rTMS in DOC patients and attempted to propose a prediction algorithm to discriminate between DOC patients who would respond to rTMS treatment from those who would not.Methods: Twenty-five DOC patients were enrolled in this study. Over 4 weeks, each patient received 20 sessions of 20 Hz rTMS that was applied over the left dorsolateral prefrontal cortex (DLPFC). For each patient, resting-state EEG was recorded before and immediately after one session of rTMS to assess the neurophysiologic modification induced by rTMS. The coma recovery scale revised (CRS-R) was used to define responders with improved consciousness.Results: Of the 25 DOC patients, 10 patients regained improved consciousness and were classified as responders. The responders were characterized by more preserved alpha power and a significant reduction of delta power induced by rTMS. The analysis of receiver operating characteristic (ROC) curves showed that the algorithm calculated from the relative alpha power and the relative delta power had a high accuracy in identifying DOC patients who were responders.Conclusions: DOC patients who had more preserved alpha power and a significant reduction in the delta band that was induced by rTMS are likely to regain improved consciousness, which provides a tool to identify DOC patients who may benefit in terms of therapeutic consciousness.