bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efeito da manipulação visceral na dor, mobilidade e incapacidade funcional em pessoas com Capsulite Adesiva de ombro direito
Authors: Ghillodia Aarti , Gandhi Balaji Karunanithi 
Published: November 2020

INTRODUÇÃO: A capsulite adesiva é uma condição dolorosa comum e debilitante da articulação glenohumeral que afeta cerca de 2 a 5% da população. Os órgãos internos e o sistema musculoesquelético são interligados por meio das membranas de sustentação. A tensão nessas membranas pode causar ainda mais restrições mecânicas, dor nas estruturas musculoesqueléticas e também restringir a mobilidade de órgãos viscerais. OBJETIVO: Explorar o efeito da manipulação visceral específica de órgãos na capsulite adesiva em pessoas afetadas no ombro direito. METODOLOGIA: Vinte indivíduos com capsulite adesiva foram avaliados para elegibilidade, dos quais 14 foram recrutados usando o método de amostragem por conveniência. Duas sessões de manipulação visceral comparada com manipulação placebo foram administradas nas primeiras duas semanas, seguidas de duas sessões de manipulação visceral do fígado nas duas semanas seguintes. O goniômetro digital, o nível de dor, a incapacidade no ombro e o esfigmomanômetro modificado foram usados para medir os resultados pré e pós intervenção. RESULTADOS: A comparação dos resultados entre os grupos mostrou uma diferença estatisticamente significativa nos escores de amplitude de movimentos [flexão (p = 0,001), rotação externa (p = 0,001), rotação interna (p = 0,001)], dor no ombro e escore do índice de incapacidade (0,004). Nenhuma mudança significativa foi observada no resultado de força. CONCLUSÃO: Duas sessões de manipulação visceral para o fígado podem ser benéficas na melhora da mobilidade do ombro direito, dor e incapacidade. O número de registro no Clinical Trial é 019/09/028271.
Efficacy of manual therapy on somatic tinnitus dual modulatory factors: a study protocol
Authors: Sharma Palak , Goyal Manu , Kothiyal Saumya 
Published: November 2020

BACKGROUND AND PURPOSE: The literature has shown promising effect of manual therapy in improving the severity of somatic tinnitus.However, no previous study has concentrated onevaluating the combined effect of temporomandibular joint and cervical spine muscles. The purpose of the study is to evaluate the efficacy of manual therapy on somatic tinnitus dual modulatory factors (TMD and cervical spine). METHODS/DESIGN: Thirty nine patients with somatic tinnitus will be randomly assigned to one of the three groups i.e., A(Cervicogenic somatic tinnitus),B(TMJ induced somatic tinnitus) and C(Dual modulatory factors induced somatic tinnitus) respectively. This multi group, parallel arms, pre-test post-test, single centre, randomized clinical trial with three parallel groups will receive six treatment sessions of integrated manual therapy on alternate days for two weeks. Postural re-education exercises will be advised to the patients as home exercises.The primary outcome measure will be Tinnitus Handicap Inventory (THI) and secondary outcome measures include Visual Analogue Scale (VAS) and Digitalized Calibrated Algometer (DCA) to measure pre and post intervention effect of the treatments. DISCUSSION: The efficacy of manual therapy in patients with somatic tinnitus in each group will be established with this study.TRIAL REGISTRATION: Clinical Trials Registry - India. (CTRI/2020/03/024394)Universal trial number- U1111-1248-3141
Is it an advantage or disadvantage to usage angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in COVID-19 patients?
Authors: Gurlek Feridun , Tasdemir Eyyüp 
Published: November 2020

Background: The use of angiotensin converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) is an important problem for clinicians who treat coronavirus disease (COVID-19) in patients with hypertension. The aim of the study was to reduce the confusion in this matter to some extent.Methods: This study was carried out in the Health Sciences University, Bursa High Specialization Training and Research Hospital between 23 March to 23 June 2020. Patients were evaluated using thorax computed tomography (CT) taken during hospitalization with severity and risk scoring, confusion, uraemia, respiratory rate, blood pressure, age ≥65 years, score >2 (CURB-65) for pneumonia.Results: The rate of severe pneumonia was significantly higher in the group using ACEI and ARBs. CURB 65 high risk observation rate was significantly higher in the group with ACEI and ARB using. The rate of severe pneumonia observed was significantly higher in the any antihypertensive drugs using group. This risk height is more pronounced in those using ACEI and ARBs. The mortality rate of our 500 patients with COVID-19 was 2.2% (11/500). There was no history of hypertension in these 4 patients, but 1 (1/4) of these 4 patients had diabetes. Six patients were taking ACEI and/or ARB in combination with their diuretic, calcium channel blocker and beta blocker. Only one patient was taking calcium channel blocker and beta blocker. Conclusions: The risk of severe pneumonia may increase in COVID-19 positive patients using any antihypertensive drug. It was more pronounced in those using ACEI and ARB. We believe that more comprehensive studies are needed in this about.
Effect of baclofen on physiotherapy in the management of spastic cerebral palsy via gross motor function measure
Authors: Ali Tabassum , Das Bismay , Mohanty Chhandamayee , Prasad Rajniti , Das B. K. , Anand Tripti 
Published: November 2020

Background: Cerebral palsy is the most common cause of physical disability in children. The gross motor function measure-66 (GMFM-66) is an observational clinical measure designed to evaluate gross motor function in children with cerebral palsy (CP). The aim of this study was to explore pediatric physiotherapists’ experiences with the gross motor capacity with CP by implementing a short-term intervention.Methods: This study was performed in the Department of Anatomy and Department of Pediatrics, University Hospital, Banaras Hindu University, Varanasi and Kiran Society, Varanasi. Patients aged between 2 years to 14 years of both sexes satisfying the inclusion and exclusion criteria were randomly enrolled into two groups; Group A included 60 patients who received only physiotherapy and Group B included 60 patients who received baclofen along with physiotherapy. Ethical clearance was obtained from the concerned authority. Data management and statistical analysis were performed using MS excel.Results: Percentage of spastic diplegia were 20.0% and 16.6% and percentage of spastic quadriplegia were 31.6% and 26.6% in group A and group B respectively. Before treatment mean score of GMFM for group A was increased to after 3 months of treatment and which further increased to after 6 months of treatment when compared to group B as their baseline mean score of GMFM was after 3 months of treatment and it increased after 6 months of treatment.Conclusions: The findings suggest the GMFM to be a useful and reliable instrument for assessing motor function and treatment outcome in CP.
Association of fibroblast growth factor 21 with oxidative stress and lipid profile in type 2 diabetes
Authors: R. Vineetha K. , K. Santha , R. Inmozhi , S. Periyasamy , G. Kanakasabai , K. Baskaran 
Published: November 2020

Background: Cardiovascular disease is the most prevalent cause of morbidity and mortality in diabetic patients. Fibroblast growth factor 21 (FBG 21) is an endocrine factor that regulates glucose and lipid metabolism, insulin resistance, and obesity. Blood levels of FGF21 are elevated in patients with atherosclerosis, macrovascular, and microvascular complications of diabetes, possibly due to a compensatory up regulation. Studies reported that FGF21 is an important regulator of mitochondrial and oxidative stress. The role of FGF21 in chronic diseases and the diminished oxidative stress observed with anti-diabetic therapy has been the target of new studies. Current study aimed to evaluate serum FGF21 levels and its association with oxidative stress and lipid profile levels in type 2 diabetic patients.Methods: 100 controls and 100 diabetic patients on oral hypoglycemic drugs between 35-55 years of age without any cardiac, renal, liver, and thyroid dysfunction were selected for this study. Oxidative stress (MDA), total antioxidant status (FRAP), and FGF21 were measured. FGF21 was analyzed by ELISA methods. Serum MDA was assessed by the method of Yagi serum total antioxidant status was measured by the method of Benzie et al.Results: FGF21 level was increased in diabetic patients compared with controls. There was a significant positive correlation of FGF21 with MDA (r=0.875, p<0.01) and negative correlation with FRAP observed (r= -0.867 p<0.01). There was also positive correlation of FGF21 with total cholesterol (r=0.499, p<0.01), triglycerides (r=0.648, p<0.01), LDL-cholesterol (r=0.337, p<0.01) and negative correlation with HDL-cholesterol (r= -0.172, p<0.05) were observed.Conclusions: Increased oxidative stress and decreased antioxidant status were observed in diabetics. This could be due to dyslipidemia and increased generation of free radicals. High levels of FGF21 observed in our study might represent its resistant state and the compensatory response to maintain metabolic homeostasis. Further studies are needed to explore the role of FGF21 as a novel marker in predicting cardiovascular risk in diabetic patients.
Prevalence of vitamin D deficiency in patients of hypertensive disorders of pregnancy and normal pregnant women
Authors: Sharma Asha , Choudhary Jaya , Joshi Piyush , Bardhar Neha 
Published: November 2020

Background: The aim of this study was to compare vitamin D level in normal pregnant women and patients of hypertensive disorders of pregnancy and to study the prevalence of vitamin D deficiency in patients of hypertensive disorders of pregnancy and normal pregnant women.Methods: 50 women affected by hypertensive disorders of pregnancy and 50 normal pregnant women more than 20 weeks of gestation, admitted to the ward or to labour room in the Obstetrics and Gynaecology Department, of Mahatma Gandhi Medical College and Hospital were enrolled in the study. Assessment of serum 25 hydroxy vitamin D was done by chemiluminescent immunoassay method.Results: Serum vitamin D levels were low in women with hypertensive disorders of pregnancy with mean serum vitamin D level 13.66±7.358 ng/ml as compared to normal normotensive pregnant women 21.14±8.241ng/ml, which is statistically significant (p=0.001). Mean vitamin D level in study population was 17.40±8.634 ng/ml. The prevalence of vitamin D deficiency in hypertensive disorders of pregnancy group was very high 88% compared to 50% in normal normotensive pregnant women group. The difference was statistically significant (p=0.001). vitamin D deficiency was found among 69% in study population. Conclusions: Vitamin D levels are deficient in patients of hypertensive disorders of pregnancy as compared to normal pregnant women. There is increased prevalence of vitamin D deficiency with hypertensive disorders of pregnancy suggesting that vitamin D deficiency can be a risk factor for the development of hypertensive disorders of pregnancy.
Neuropathy in the setting of alcoholism-an entity less thought of
Authors: Paneyala Shasthara , C. Nemichandra S. , Sundaramurthy Harsha , Colaco K. Vimala Christina 
Published: November 2020

Disulfiram is a commonly used adjunctive treatment in the management of alcohol dependency. It has been noted that disulfiram can induce peripheral neuropathy, the mechanism of which has not been clearly determined. A 35-year-old patient, reformed alcoholic, on disulfiram presented with complaints of painful distal dysesthesias and foot drop. Clinical examination revealed bilateral foot drop without any objective sensory loss. Patient was evaluated for the same and routine blood investigations including vitamin B-12, inflammatory and virological markers were found to be normal. Nerve conductions studies revealed in excitable bilateral common peroneal and tibial nerves. Possibility of disulfiram induced peripheral neuropathy was thought of and drug was withdrawn. Patient was followed up and after two months improvement in motor power and reduction in paraesthesia’s was noted. Disulfiram is a commonly used drug, the uncommon side effect of which is distal predominant axonal neuropathy. This must be kept be kept in mind when evaluating a patient presenting with features of peripheral neuropathy, on a background of alcohol abuse.
Role of pre-operative ultrasonography in assessment of technical difficulties during laparoscopic cholecystectomy requiring conversion to open procedure
Authors: Chatterjee Debarghya , Vakil Rakesh , Sharma Rajeev , Mohanty Arnab , Patras Elisheba 
Published: November 2020

Background: Cholecystectomy is the most common major abdominal surgery of the biliary tract and the second most common abdominal surgery performed in recent times. Today, laparoscopic cholecystectomy is the treatment of choice for symptomatic gallstones. Ultrasound is a non-invasive, painless investigation that will show stones in the gallbladder with sensitivity and specificity of more than 90%. The study aims at evaluating the accuracy of certain ultrasound parameters to predict a difficult laparoscopic cholecystectomy. Methods: Prospective observational study. The selected patients were explained about the procedures of ultrasonography and laparoscopic cholecystectomy, and about the advantages and disadvantages of laparoscopic cholecystectomy, along with the possibility of conversion to open procedure. Informed consent was taken. General particulars of patients, relevant history & findings on physical examination, laboratory investigations, ultrasonographic features and operative findings were noted in the study proforma. For data analysis, categorical variables were expressed as frequencies and percentages. Sensitivity, specificity and p values were calculated. P value<0.05 was considered to be statistically significant.Results: Significant association was found between all the independent ultrasound parameters and a difficult laparoscopic cholecystectomy. Presence of contracted gall bladder was found to be significantly associated with conversion to open cholecystectomy.Conclusions: It was found that ultrasonography can be a useful tool in predicting a difficult laparoscopic cholecystectomy.
A case of elevated carbohydrate antigen 19-9 with a benign cause
Authors: Parikh Jayesh V. , Dalal Parth R. , Baraiya Piyush N. , Vishwakarma Sachin R. 
Published: November 2020

Serum carbohydrate antigen 19-9 (CA 19-9), a marker of malignant tumors, is generally slightly elevated in benign conditions. We report a case of cholecystitis with perforated gall bladder with significantly elevated level of serum CA 19-9 based on abdomen computed tomography and intra operative findings. A 70 years diabetic and hypertensive female presented with right hypochondriac pain associated with occasional itching and nausea without vomiting with markedly raised CA 19-9 (1554 U/ml) with CECT abdomen suggestive of perforated gall bladder with cholecystitis. Patient electively operated for open cholecystectomy and per operative findings were distended gall bladder with multiple calculi within with edematous gall bladder wall and adhesions between gall bladder and omentum and colon. Gall bladder removed and biopsy suggestive of chronic calculus cholecystitis. On post-operative day 5th and 7th CA 19-9 was repeated twice and drastic fall to 5 U/ml and 12 U/ml respectively. Chronic calculus cholecystitis with high elevation of CA 19-9 is rare.
Strategies to prevent extinction of plastic surgery
Authors: Agrawal Neeraj K. 
Published: November 2020

“What we need is not the will to believe, but the wish to find out.” William WordsworthPlastic surgery is a rare combination of carpentry and aesthetics. These skills are so judgmental that the perception of the ideal form varies radically between the surgeons. Plastic surgery being surface surgery is unique as the results are obvious and almost instantaneous. Younger surgeons usually face difficulties in satisfying the patients because of the visibility of surgical results. Litigation and compensation issues may also dissuade medical students to join the revered specialty. Many other issues related to the specialty merit due attention.
Cannulated cancellous screws versus dynamic hip screw in femoral neck fractures: a comparison in productive age group at tertiary care hospital of North India
Authors: Arfee Sakib , Arfee Akib , Arfee Adnan Aadil 
Published: November 2020

<p class="abstract"><strong>Background:</strong> Since intracapsular fracture neck femur was recognized by Ambrose Pare almost 4 centuries back, the management of intracapsular neck femur fracture has undergone many changes. The multitude of various implants designed and techniques available for its treatment themselves indicate the inadequacy of the various methods of treatment. Objective was to compare cannulated cancellous screws (CCS) versus dynamic hip screw (DHS) in femoral neck fractures in productive age group.</p><p class="abstract"><strong>Methods:</strong> This observational study with both prospective and retrospective data analysis of patients operated by different surgeons in same hospital setup has been conducted from March, 2018 to February, 2020 at the department of Orthopedics, Government Medical College (GMC), Jammu. 105 cases satisfying the inclusion criteria admitted in GMC Jammu were included clinically and radiologically. Total number of patients included in the study was 97 patients as 8 patients were lost to follow-up. Functional outcome was evaluated by using Harris hip scoring.<strong></strong></p><p class="abstract"><strong>Results:</strong> In our study 8 CCS cases were lost to follow up. Total 97 of cases were followed up till one year both radiologically and clinically after a given time intervals and final assessment done on the basis of Harris hip score. Among 97 cases 71 were males most of them in age group of 41-45 years and 26 were females with 46-50 years age group predominance. 47.42% fractures were classified as type III in garden’s staging. </p><p class="abstract"><strong>Conclusions:</strong> DHS is a better implant than CCS in hands of doctors who lack of expertise and precision i.e. required for CCS in fracture neck femur in young adult patients.</p>
DEPRESSIVE SYMPTOMATOLOGY AMONG IN-SCHOOL ADOLESCENTS WITH IMPAIRED HEARING
Authors: Adigun Olufemi Timothy 
Published: November 2020

Purpose of the study: This study determined incidences of depressive symptoms and associated causative contextual factors among in-school adolescents with impaired hearing in South West, Nigeria. The study determined symptoms of depression exhibited by in-school adolescents with impaired hearing vis-à-vis some associated intrapersonal causative (age, religion, gender, the onset of hearing loss, satisfaction with the home environment, and family type) variables.
Methodology: Descriptive survey design was adopted for the study. Data were collected from 236 adolescents who are either prelingually (39.1%) and postlingually (60.9%) hearing impaired with the Depressive Symptomatology Questionnaire (α = .89). Data collected over a period of 10 weeks were analysed with both descriptive and inferential statistics via SPSS version 23.
Main Findings: 58.8% of the participants scored higher on the depression scale, which is mostly characterized by loss of appetite and fearfulness. There is a significant difference (F = 7.61; p < 0.05) in the expression of depressive symptoms between gender and across variants in the onset of deafness (F = 3.59; p < 0.05) and family type (F = 23.14; p < 0.05). Academic stressor and lack of access to information were found to be the major source of their depression.
Applications of this study: This study is of importance to counselling psychologist and mental health practitioners for the development of strategic therapeutic approach geared towards positive psychosocial development of individuals with impaired hearing
Novelty/Originality of this study: The study confirms the manifestation of moderate to a high level of depressive symptoms among those in-school adolescents with impaired hearing. Academic anxiety/low grade, communication difficulties, and negative societal attitude were the major source of depression for adolescents with impaired hearing in high schools.
TRANSACTIONAL POLITICAL PRACTICES IN THE ASYMMETRIC DECENTRALIZATION SYSTEM IN ACEH (10-YEAR ANALYSIS OF SPECIAL AUTONOMY FUND MANAGEMENT PERIOD 2008-2018)
Authors: Aprita Sari Cut Maya , Suhail Ghifari Muhammad , Talib @ Khalid Kartini Aboo 
Published: November 2020

Purpose of the study: Within 10 years, the central government of Indonesia has granted the special autonomy fund to Aceh as a strategy to improve the welfare of Acehnese. Contrary, the special autonomy funds that cannot be implemented properly-affected to the poverty in Aceh-is not significantly decreased. This study aims to determine the failure of special autonomy funds to decrease poverty in Aceh.
Methodology: This research used descriptive qualitative methods by conducting the primary data through interviews, also secondary data through books, journals, newspapers, and other related sources. The analysis data is doing by using Transactional Political Theory.
Main Findings: The results of this study indicate that asymmetric decentralization can be seen from the weak Regional Economic Growth Rate and the slow improvement of the Quality of Human Development Index (HDI). Thus the failure was caused by two things, namely: the thick Political Content of The Local Political Elite and the Domination of Local Political Elite in the Management of Aceh's Special Autonomy Fund in the Compilation of Planning and Work Programs. The absence of control in the management of special autonomy funds is based on project performance without good planning, and the existence of interest-based planning in the management of special autonomy funds that based on populist activity programs following the wishes of politicians which have an impact on weak regional economic growth, slow index improvement of human development quality, high poverty rates, and high unemployment in Aceh.
Applications of this study: The finding of this study offered the evaluation systems for the government of Aceh to strengthen better local government governance, especially in increasing budget planning and implementation efficiency and strengthening regulations, and implementing an e-planning system to select program activities from the Aceh special autonomy fund.
Novelty/Originality of this study: Based on the literature review conducted, there were limited publications which are focusing on the failure of autonomy funds in Aceh. Therefore this research will enrich the publication that concerns the failure of managing special autonomy funds in Aceh.