bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immature Platelets and Risk of Cardiovascular Events among Patients with Ischemic Heart Disease: A Systematic Review
Authors: Faber Julie , Hvas Anne-Mette , Kristensen Steen Dalby , Grove Erik Lerkevang , Adelborg Kasper 
Published: December 2020

AbstractBackground Immature platelets are larger and may be more thrombogenic than mature platelets. This systematic review included studies on the association between mean platelet volume (MPV), immature platelet count (IPC), and immature platelet fraction (IPF) and the risk of major cardiovascular events (MACEs) in patients with acute coronary syndrome (ACS) or stable coronary artery disease (CAD).Methods The literature search included studies in PubMed, Embase, Web of Science, and Cochrane Library. The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Effect estimates that included multivariate adjusted odds ratios, relative risks, or hazard ratios were extracted.Results Forty-two studies were identified. High MPV was positively associated with MACE in 20 of 26 studies of patients with ACS, four of five studies in patients with stable CAD, and in all six studies comprising a combined population with ACS and stable CAD. Using continuous models of MPV in patients with ACS, effect estimates varied from 0.90 (95% confidence interval [CI]: 0.95–1.03) to 1.66 (95% CI: 1.32–2.09). The strength of these associations was broadly similar among patients with stable CAD and in combined populations. Five studies investigated IPC or IPF as exposures and all reported positive associations with MACE among patients with ACS, stable CAD, or in combined populations.Conclusion This review demonstrated clear evidence for positive associations between measures of immature platelets and subsequent risk of MACE in acute and stable ischemic heart disease patients.
Targeting transcriptional regulation of SARS-CoV-2 entry factorsACE2andTMPRSS2
Authors: Qiao Yuanyuan , Wang Xiao-Ming , Mannan Rahul , Pitchiaya Sethuramasundaram , Zhang Yuping , Wotring Jesse W. , Xiao Lanbo , Robinson Dan R. , Wu Yi-Mi , Tien Jean Ching-Yi , Cao Xuhong , Simko Stephanie A. , Apel Ingrid J. , Bawa Pushpinder , Kregel Steven , Narayanan Sathiya P. , Raskind Gregory , Ellison Stephanie J. , Parolia Abhijit , Zelenka-Wang Sylvia , McMurry Lisa , Su Fengyun , Wang Rui , Cheng Yunhui , Delekta Andrew D. , Mei Zejie , Pretto Carla D. , Wang Shaomeng , Mehra Rohit , Sexton Jonathan Z. , Chinnaiyan Arul M. 
Published: December 2020

SignificanceNew therapeutic targets are urgently needed against SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic. Results in this study show that targeting the transcriptional regulation of host entry factorsTMPRSS2andACE2is a viable treatment strategy to prevent SARS-CoV-2 infection. In particular, inhibitors of androgen receptor (AR) or bromodomain and extraterminal domain (BET) proteins are effective against SARS-CoV-2 infection. AR inhibitors are already approved in the clinic for treatment of prostate cancer and are under investigation in COVID-19 patients; BET inhibitors are also in clinical development for other indications and could be rapidly repurposed for COVID-19.
The presentational dimension of Geert Wilders’s populist argumentative style
Authors: Jansen Henrike , Leeuwen Maarten van 
Published: December 2020

Abstract
This study responds to van Eemeren’s (2019, 2021) call for research on the prototypical argumentative styles used in particular domains or
communicative activity types by particular individuals or groups. It explores the argumentative style of Dutch politician Geert
Wilders in presenting populist arguments, i.e., arguments claiming that if many people hold a certain standpoint, this standpoint
should be accepted. A corpus study of 27 texts taken from the website of Wilders’s political party reveals four characteristics of
this presentation that deviate significantly from the general descriptions of this type of argument given in the textbooks: (1) absence of indicators, (2) implicit standpoint, (3) wide range of verbs to indicate what “the people” think or believe, (4) use of
a construction indicating that the speaker is acting as a mouthpiece (“on behalf of the people, I say”).
Six related essays on argumentative style
Authors: Eemeren Frans H. van 
Published: December 2020

Abstract
This introduction to the special issue devoted to argumentative style describes the way in which this collection of six
papers came about. It recapitulates the main thrust of the issues that are included. All authors share the pragma-dialectical perspective on
argumentative style set forth in the first contribution, in which argumentative style is connected with strategic manoeuvring. In analysing
argumentative styles, they concentrate on different kinds of argumentative discourses and have a different emphasis in carrying out their
analyses.
Examining argumentative style
Authors: Eemeren Frans H. van 
Published: December 2020

Abstract
In this theoretical expose, it is argued that the notion of argumentative style is more encompassing and at the same time
more specific than the more familiar notion of linguistic style. According to van Eemeren, argumentative styles always have three
dimensions: the selection of standpoints, starting-points, arguments or other argumentative moves (topical choice dimension), the adjustment
of argumentative moves to the frame of reference and preferences of the listeners or readers (audience demand dimension), and the choice of
verbal or non-verbal means for advancing argumentative moves (presentational dimension). In argumentative discourse, the three dimensions of
argumentative style manifest themselves in the argumentative moves made in trying to resolve a difference of opinion (analytic overview),
the dialectical routes chosen in making these argumentative moves (argumentative pattern) and the strategic considerations brought to bear
in this endeavour (strategic design). Van Eemeren explains what this means in practice by discussing the distinctive features of the three
dimensions of two general categories of argumentative styles that can be regularly encountered, in one variant or other, in argumentative
discourse: detached argumentative styles and engaged argumentative styles.
A feasibility study of radar-based shape and reflectivity reconstruction using variational methods
Authors: Bignardi Samuel , Joseph Yezzi Anthony , Yildirim Alper , Barnes Christopher F , Sandhu Romeil 
Published: December 2020

Abstract
Remote sensing radar techniques provide highly detailed imaging. Nevertheless, radar images do not offer directly retrievable representations of shape within the scene. Therefore, shape reconstruction from radar typically relies on applying post-processing computer vision techniques, originally designed for optical images, to radar imaging products. Shape reconstruction directly from raw data would be desirable in many applications, e.g. in computer vision and robotics. In this perspective, inversion seems an attractive approach. Nevertheless, inversion has seldom been attempted in the radar context, as high frequency signals lead to energy functionals dominated by tightly packed narrow local minima. In this paper, we take the first step in developing a framework in which radar signals and images can be jointly used for shape reconstruction. In particular, we investigate the feasibility of shape reconstruction by inversion of pulse-compressed radar signals alone, collected at sparse locations. Motivated by geometric methods that have matured within the fields of image processing and computer vision, we pose the problem in a variational context obtaining a partial differential equation for the evolution of an initial shape towards the shape-reflectivity combination that best reproduces the data. While doing so, we highlight several non-obvious difficulties encountered and discuss how to surpass them. We illustrate the potential of this approach through three simulated examples and discuss several implementation choices, including boundary conditions, reflectivity estimation, and radiative models. The success of our simulations shows that this variational approach can naturally accommodate radar inversion and has the potential for further expansion towards active surfaces and level set applications, where we believe it will naturally complement current applications with optical images.
The electron-phonon coupling constant, Fermi temperature and unconventional superconductivity in the carbonaceous sulfur hydride 190 K superconductor
Authors: Talantsev E F 
Published: December 2020

Abstract
Recently, Snider et al (2020 Nature
586 373) reported on the observation of superconductivity in highly compressed carbonaceous sulfur hydride, H
x
(S,C)
y
. The highest critical temperature in H
x
(S,C)
y
exceeds the previous record of T
c = 280 K by 5 K, as reported by Somayazulu et al (2019 Phys. Rev. Lett.
122 027001) for highly compressed LaH10. In this paper, we analyze experimental temperature-dependent magnetoresistance data, R(T,B), reported by Snider et al. The analysis shows that H
x
(S,C)
y
compound exhibited T
c = 190 K (P = 210 GPa), has the electron–phonon coupling constant λ
e−ph = 2.0 and the ratio of critical temperature, T
c, to the Fermi temperature, T
F, in the range of 0.011 ⩽ T
c/T
F ⩽ 0.018. These deduced values are very close to the ones reported for H3S at P = 155–165 GPa (Drozdov et al 2015 Nature
525 73). This means that in all considered scenarios the carbonaceous sulfur hydride 190 K superconductor falls into the unconventional superconductor band in the Uemura plot, where all other highly compressed super-hydride/deuterides are located. It should be noted that our analysis shows that all raw R(T,B) data sets for H
x
(S,C)
y
samples, for which Snider et al (2020 Nature
586 373) reported T
c > 200 K, cannot be characterized as reliable data sources. Thus, independent experimental confirmation/disproof for high-T
c values in the carbonaceous sulfur hydride are required.
Phase diagram, stability and magnetic properties of nonlinear excitations in spinor Bose–Einstein condensates
Authors: Katsimiga G C , Mistakidis S I , Schmelcher P , Kevrekidis P G 
Published: December 2020

Abstract
We present the phase diagram, the underlying stability and magnetic properties as well as the dynamics of nonlinear solitary wave excitations arising in the distinct phases of a harmonically confined spinor F = 1 Bose–Einstein condensate. Particularly, it is found that nonlinear excitations in the form of dark–dark–bright solitons exist in the antiferromagnetic and in the easy-axis phase of a spinor gas, being generally unstable in the former while possessing stability intervals in the latter phase. Dark–bright–bright solitons can be realized in the polar and the easy-plane phases as unstable and stable configurations respectively; the latter phase can also feature stable dark–dark–dark solitons. Importantly, the persistence of these types of states upon transitioning, by means of tuning the quadratic Zeeman coefficient from one phase to the other is unravelled. Additionally, the spin-mixing dynamics of stable and unstable matter waves is analyzed, revealing among others the coherent evolution of magnetic dark–bright, nematic dark–bright–bright and dark–dark–dark solitons. Moreover, for the unstable cases unmagnetized or magnetic droplet-like configurations and spin-waves consisting of regular and magnetic solitons are seen to dynamically emerge remaining thereafter robust while propagating for extremely large evolution times. Interestingly, exposing spinorial solitons to finite temperatures, their anti-damping in trap oscillation is showcased. It is found that the latter is suppressed for stronger bright soliton component ‘fillings’. Our investigations pave the wave for a systematic production and analysis involving spin transfer processes of such waveforms which have been recently realized in ultracold experiments.
Non-local correlation between two coupled qubits interacting nonlinearly with a two-mode cavity: Bell function, Trace norm and Bures distance quantifiers
Authors: Mohamed A-B A , Khalil E M , Abdel-Khalek S 
Published: December 2020

Abstract
In this paper, we study the dynamics of two coupled qubits interacting with a two-mode parametric amplifier cavity through the nonlinear interactions of the photon processes under the intrinsic decoherence. The nonlinear unitary interactions lead to generating different types of nonlocal correlations via Bell nonlocality, trace-norm measurement-induced non-locality (MIN), and Bures-distance entanglement. Based on the intrinsic decoherence, the two-qubit states have stationary amounts of the MIN-correlation and Bures distance entanglement with more stability. It is found that the qubit–qubit interaction coupling is affected as additional decoherence. It leads to more oscillations and stability. The enhancement of the amount of the generated nonlocal correlations depends on the superposition of Barut-Girardello coherent states. The phenomenon of sudden birth/death and the Bell non-locality can be enhanced when the two-mode parametric amplifier cavity is initially prepared in the coherent states.
KNITU-KAI educational cluster: teaching mathematics
Authors: Yakupov Z Ya , Galimova R K , Dorofeeva S I , Nikiforova S V , Valishin N T 
Published: December 2020

Abstract
The system of mathematical education at the A. N. Tupolev Kazan National Research Technical University (KNITU-KAI) is described. It is suggested that the mathematics course at a technical university should be diversified. This should be ensured for different areas by the difference in the selection of material, the placement of emphasis on the relevance of the studied sections of mathematics in the specialized disciplines. It is proposed that the development of interest in mathematics for future engineers can be provided by solving professionally oriented problems, showing the use of mathematical sections using specific examples from the disciplines of the professional cycle, and thus drawing the attention of junior students to the need to have solid mathematical knowledge. The author points out the significant role of online training courses at KNITU-KAI. It is assumed that e-courses allow a deeper study of the material presented by the teacher in lectures and practical classes, and they also provide an opportunity to qualitatively prepare for control activities, for intermediate certification.
Strategy and tactics of teaching mathematics at a technical university
Authors: Vershinina L P , Vershinin M I 
Published: December 2020

Abstract
The role of mathematics in the formation of innovative thinking of students is determined. The strategy and tactics of teaching mathematics in solving the problem of integration of fundamental and professional education are proposed. The role of integrative disciplines as a means of unifying the links between mathematics and special disciplines was revealed. It is shown that the course of mathematics in a technical university should reflect continuously developing trends in applied mathematics. The need to include general mathematical courses in the curricula at all stages of training including in the magistracy is justified. Examples illustrating the proposed concept are given.
Pedagogical conditions for the formation of the students’ scientific worldview when teaching biology
Authors: Kondaurova T I , Fetisova N E , Vedeneev A M , Zverev A V , Reut L A 
Published: December 2020

Abstract
The theoretical aspects are revealed regarding the role of biology as one of the leading sciences of nature, in the formation of the students’ scientific worldview. It is emphasized that the content of the school subject “Biology”, methods, forms and means of study thereof, should be aimed at the formation of the students’ worldview. There are highlighted the main pedagogical conditions of the stepwise formation of the students’ worldview when teaching biology, taking into account the specific kinds of activity of the students and the teacher. As a structural unit of the pedagogical process there are designated the person-developing learning situations based on the relationship between the educational activity and life experience as well as the independent creative activity of the student, for the implementation of which the traditional content and techniques of teaching biology are reconstructed-the biological concepts of the worldview nature, creative tasks, problem situations, worldview-oriented issues with regard to the age-specific features of the students are emphasized. The obtained results of the pedagogical diagnostics, aimed at identifying the level of the formedness of the students’ scientific worldview, confirmed the effectiveness of the chosen pedagogical conditions.
On the issue of the level of estimation for professional mobility of the future expert in the field of operating security
Authors: Brukhov E N , Kovtunenko L V , Kalach E V , Melnik O E 
Published: December 2020

Abstract
The article discusses the most important problem associated with the formation of professional mobility of future specialists in the field of life safety in educational institutions of the Ministry of Emergencies based on modular training. The modern social and economic situation actualizes the personality professional educational problem, the initiatives and competent, corporate, professional and mobile preparation in higher school. The authors, based on indicators of the formation of professional mobility and psychodiagnostic techniques that allow us to assess the level of formation of each of the selected indicators, identified and substantively characterized the levels of formation of professional mobility of cadets-future employees of the Ministry of Emergencies: partial, potential, updated.
Training of teachers for engineering education in Russian schools
Authors: Gromova E M , Berkutova D I , Gorshkova T A 
Published: December 2020

Abstract
For the scientific and technological development of the Russian Federation, it is necessary to train personnel since school days. With this approach to engineering education, the training of highly qualified teachers becomes especially relevant. These “technology teachers of the XXI century” should not only be motivated to work with students, but also demonstrate modern digital, engineering and technological competencies. The following research methods were used: analysis of scientific papers on the problems of engineering education in schools; the concept of teaching the subject area "Technology" in Russian schools that implement the main general education programs, the latest educational and methodological complexes for technology; analysis of the legal framework and systematization of the leading normative documents determining changes in the professional and pedagogical education of technology teachers; analysis and generalization of the author’s experience in the development of basic professional educational programs; pedagogical experience in training future technology and informatics teachers, as well as experience in teaching technology to schoolchildren; analysis of the impact of digitalization of education and professional activity on the transformation of the ways of their implementation, as well as the processes of interpersonal interaction and professional identification; diagnostics according to L. B. Schneider "Professional Identity", questionnaires and descriptive statistics; generalization and interpretation of research results. A detailed analysis of psychological and pedagogical research, regulatory documentation in the field of technology education allowed the authors to identify the main conditions for the training of technology teachers for the implementation of engineering education in secondary schools in Russia.
The system of mathematical education of Russia: problems, tasks, solutions
Authors: Belov F D , Smirnova A V 
Published: December 2020

Abstract
The article presents a study of the currently functioning system of mathematical education in the Russian Federation. The importance of research areas related to mathematics for the Russian and world community has been substantiated. The analysis of the implementation of the modern Concept of Mathematical Education of the Russian Federation is carried out, achievements and problems are highlighted. The changes that have affected school and university mathematics education from the moment of approval of the Concept of Mathematical Education of the Russian Federation and up to the present, the positive and negative results of these changes are shown. On the basis of a survey conducted by the authors of representatives of the leading mathematical organizations of Russia for the changes necessary from their point of view that need to be introduced into the Concept of Mathematical Education, the most important and significant proposals for improving the quality of this sphere of education have been developed.
Assessment of the application of the Universal Competencies
Authors: Masaev S N , Dorrer G A , Minkin A N , Bogdanov A V , Salal Y K 
Published: December 2020

Abstract
Application of Universal Competencies in Russian educational institutions is very important. Based on them, educational standards are invented. However, there is no universal assessment of the application of the Universal Competencies in practice. The main idea of the research is a general assessment of the application of universal competencies. For this, the activity of the enterprise is modeled. The enterprise process model is combined with the Universal Competencies. Further, the measurement is made by a universal indicator. The analysis of the dynamics of the universal indicator proves the existence of an assessment of the application of the Universal Competencies at a production facility. The integral indicator is a universal assessment of the application of the Universal Competencies.
The automated system Steach. Space designed for Programming teaching
Authors: Kizyanov A , Luchaninov D , Bazhenov R , Pronin A , Tabachuk N , Samorukov A 
Published: December 2020

Abstract
The research aims at designing and verifying an automated system for online learning in Programming languages. Such systems were designed to provide students’ independent theoretical training and exercising within in-person learning and are able to operate on their own. Nginx, Docker, Gunicorn, Django, Python, PostgreSQL, HTML5, and CSS Framework were applied. Testing was held at Sholom-Aleichem Priamursky State University and Pacific National University in the 2019-2020 academic year. Training in C++ and Python was arranged for 30 students for the research efficiency checking. The researchers found out the system used could make Programming learning more efficient. The results showed that it was improved by 30% in an experimental group and by 17% in a control group. The survey data used defined that the participants of the experiment (students, lecturers, experts) appreciated the software solution. The designed system Steach.space has a user-friendly interface, contains modules for developing integrated/built-in courses, providing teaching aids and tests, computer-assisted verification of assignments in Programming, and observing statistics/history on student learning. The software can be used for teaching programming languages, as well as other subject domains.