bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN ANTARA ASUPAN PROTEIN DAN KADAR PROTEIN AIR SUSU IBU
Authors: Prastiyani Lien Meilya Muriasti , Nuryanto Nuryanto 
Published: April 2020

Latar Belakang: ASI merupakan makanan terbaik bayi 0-6 bulan karena mengandung semua unsur zat gizi yang dibutuhkan bayi serta mengandung antibodi untuk melindungi bayi dari penyakit. Kandungan zat gizi ASI salah satunya dipengaruhi oleh asupan zat gizi. Protein merupakan salah satu zat gizi yang berperan dalam pertumbuhan, pembentukan jaringan dan organ penting dan pertahanan tubuh bayi.Tujuan penelitian ini adalah untuk mengetahui hubungan antara asupan protein dengan kadar protein air susu ibu (ASI).Metode: Jenis penelitian ini adalah observasional dengan desain studi cross sectional. Jumlah sampel sebanyak 33 orang ibu menyusui bayi 0-6 bulan di wilayah Kecamatan Candisari dan Kecamatan Tembalang yang dipilih secara acak. Asupan protein diperoleh melalui recall 3x24 jam melalui wawancara dengan metode food recall dengan hari yang berbeda. Kadar protein ASI dianalisis dengan metode Kjeldahl. Hubungan antara asupan protein dengan kadar protein ASI diuji menggunakan uji korelasi Rank Spearman.Hasil: Rerata asupan protein ibu menyusui 58,06±10,51gram dan rerata tingkat asupan protein 49,74±9,29%.Hasil penelitian menunjukkan adanya hubungan signifikan antara asupan protein dengan kadar protein ASI dengan nilai p= 0,029 (p<0,05). Simpulan: Terdapat hubungan signifikan antara asupan protein dengan kadar protein ASI.
HUBUNGAN STATUS GIZI DAN KUALITAS TIDUR DENGAN KUALITAS HIDUP PADA LANJUT USIA
Authors: Hermawan Febriyanti , Widyastuti Nurmasari , Tsani A Fahmy Arif , Fitranti Deny Yudi 
Published: April 2020

Latar Belakang : Jumlah penduduk lanjut usia mengalami peningkatan setiap tahunnya. Peningkatan kuantitas lanjut usia harus diseimbangkan dengan peningkatan kualitas hidupnya. Status gizi dan kualitas tidur menjadi masalah yang dialami oleh lansia. Penelitian ini bertujuan untuk menganalisis hubungan status gizi dan kualitas tidur dengan kualitas hidup pada lanjut usia.Metode : Penelitian ini menggunakan metode cross-sectional. Penelitian ini dilaksanakan di Kelurahan Kalisegoro Kecamatan Gunungpati Kota Semarang. Berdasarkan hasil skrining 254 lanjut usia didapatkan 44 subjek menggunakan metode simple random sampling. Data Status gizi didapatkan melalui pengukuran langsung menggunakan timbangan digital dan alat pengukur tinggi lutut. Data kualitas tidur dan kualitas hidup diperoleh melalui wawancara menggunakan form Pittsburgh Sleep Quality Index (PSQI) dan World Health Organization Quality of Life (WHOQOL-BREF). Hasil : Tidak terdapat hubungan antara status gizi dengan kualitas hidup (r = 0,251; p = 0,101) dan tidak terdapat hubungan antara kualitas tidur dengan kualitas hidup (r = 0,027; p = 0,862).Simpulan : Tidak terdapat hubungan antara status gizi dan kualitas tidur dengan kualitas hidup pada lanjut usia.
MEDIDAS DE REDUÇÃO DE GERAÇÃO DE RESÍDUOS SÓLIDOS NA CONSTRUÇÃO CIVIL COMO ATENDIMENTO DOS REQUISITOS DE SUSTENTABILIDADE DO PBQP-H/SIAC
Authors: Haubrick Suelen Oliveira , Gonçalves José Roberto Moreira Ribeiro 
Published: April 2020

O setor da construção civil é grande fonte geradora de resíduos sólidos no país. Estudos apontam que a quantidade de resíduos gerados pelas construções se intensificaram devido ao crescimento da população urbana. Resíduos sólidos não tratados e sem destinação final adequada trazem consequências negativas para o meio ambiente e população. A problemática se dá pelo fato de grande parte do setor da construção civil negligenciar as normas e leis que contemplam o tema sustentabilidade e por desconhecerem os custos deploráveis da geração de resíduos sólidos. O presente artigo tem como objetivo apresentar, através de pesquisas exploratórias, como o setor da construção civil poderá gerenciar a redução da geração de resíduos sólidos de forma que se tenha um controle e monitoramento em todo o ciclo de vida da obra. Por fim, através do presente artigo foi possível concluir que a redução da geração de resíduos sólidos será obtida ao desenvolver um adequado plano de gerenciamento de resíduos sólidos estruturado no PBQP-H/SiAC, Programa Brasileiro da Qualidade e Produtividade do Habitat e Sistema de Avaliação da Conformidade de Empresas de Serviços e Obras da Construção Civil, que estabelece critérios para redução dos resíduos sólidos gerados. Planejar estratégias para a redução desses resíduos é um ato que beneficia a natureza no quesito sustentabilidade e também traz consequências positivas para o setor da construção civil através da redução de custos com melhoria da qualidade.
CHALLENGE BASED LEARNING (CBL) NO CURSO DE ODONTOLOGIA DA UNIVATES
Authors: Teixeira Maurício Fernando Nunes , D’Ávila Otávio Pereira , Da Rosa Daiani Clesnei , Dhein Gisele , Kuhn Bruno Velho , Lopes Júlio Cesar 
Published: April 2020

INTRODUÇÃO: O curso de Odontologia da UNIVATES foi pensado a partir das diretrizes curriculares para a Odontologia e tem como premissas o desenvolvimento de pensamento crítico, autonomia dos sujeitos e aprendizagem significativa. Está organizado em um currículo modular integrado e o uso de metodologias ativas de ensino e de aprendizagem buscam a formação de habilidades e desenvolvimento de competências previstas nas diretrizes. OBJETIVO: Refletir sobre a utilização da metodologia denominada Challenge Based Learning (CBL) em um dos módulos em uma turma do curso. METODOLOGIA: Através do desenvolvimento do tema do planejamento as turmas foram divididas em grupos e a partir da definição de um tema geral (Big Idea), de relevância mundial, que afetasse o grupo desenvolvesse os outros passos da metodologia. Os grupos foram desafiados a desenvolver soluções/propostas para a realidade local e deveriam desenvolver um produto final publicável em redes sociais. RESULTADOS: Os temas elencados pelos grupos foram: HIV/AIDS, IMIGRAÇÃO, DISCRIMINAÇÃO e TRABALHO ESCRAVO. Os produtos alcançados foram um seminário em conjunto com o curso de Psicologia que envolveu toda a comunidade acadêmica da instituição sobre os temas HIV e Discriminação, com debatedores especialistas na temática e quatro peças gráficas digitais divulgadas em redes sociais. Gerando 50 compartilhamentos e 165 likes no Facebook. CONSIDERAÇÕES FINAIS: O CBL permite ao estudante ter protagonismo na busca de soluções e possibilita influenciar a comunidade a enfrentar e refletir essas situações. Além disso, os estudantes direcionam o curso de sua aprendizagem e envolvem os professores de forma solidária no papel necessário de guias.
Towards restoring proper chromosome segregation and preventing ageing
Authors: Tovini Laura , McClelland Sarah E 
Published: April 2020

The natural progressive dysfunction of most living organisms—ageing—has captured the attention of several studies, with the intention to develop rejuvenation strategies. Evidence is emerging of a positive correlation between natural ageing and chromosomal instability (CIN). In this issue of EMBO Reports, Barroso‐Vilares et al [1] now show a link between ageing and the erroneous assembly of the apparatus required for a proper cellular division. They compare this mechanism in young and naturally aged human cells and describe a strategy to delay age‐related CIN.
Amyotrophic Lateral Sclerosis Modifiers inDrosophilaReveal the Phospholipase D Pathway as a Potential Therapeutic Target
Authors: Kankel Mark W , Sen Anindya , Lu Lei , Theodorou Marina , Dimlich Douglas N , McCampbell Alexander , Henderson Christopher E , Shneider Neil A , Artavanis-Tsakonas Spyros 
Published: April 2020

AbstractAmyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder lacking effective treatments. ALS pathology is linked to mutations in several different genes indicating...Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a devastating neurodegenerative disorder lacking effective treatments. ALS pathology is linked to mutations in &gt;20 different genes indicating a complex underlying genetic architecture that is effectively unknown. Here, in an attempt to identify genes and pathways for potential therapeutic intervention and explore the genetic circuitry underlying Drosophila models of ALS, we carry out two independent genome-wide screens for modifiers of degenerative phenotypes associated with the expression of transgenic constructs carrying familial ALS-causing alleles of FUS (hFUSR521C) and TDP-43 (hTDP-43M337V). We uncover a complex array of genes affecting either or both of the two strains, and investigate their activities in additional ALS models. Our studies indicate the pathway that governs phospholipase D activity as a major modifier of ALS-related phenotypes, a notion supported by data we generated in mice and others collected in humans.
Renal Involvement and Early Prognosis in Patients with COVID-19 Pneumonia
Authors: Pei Guangchang , Zhang Zhiguo , Peng Jing , Liu Liu , Zhang Chunxiu , Yu Chong , Ma Zufu , Huang Yi , Liu Wei , Yao Ying , Zeng Rui , Xu Gang 
Published: April 2020

Significance Statement
Some cases of COVID-19 pneumonia have presented with kidney injury, and autopsy findings for patients with COVID-19 have revealed renal involvement. In this retrospective, single-center study of Chinese patients with COVID-19 pneumonia, 251 of 333 patients (75.4%) presented with renal complications, including proteinuria, hematuria, and AKI. After the median duration of 12 days of follow-up, nearly half of patients with AKI recovered from AKI within 3 weeks of onset of infection. However, patients with renal involvement had higher overall mortality (11.2%) compared with patients without renal involvement (1.2%). Adverse short-term outcomes of renal involvement were associated with severity of COVID-19 pneumonia. These findings indicate that although early renal abnormalities often resolve in such patients, intensive support and careful monitoring of severe or critical illness is appropriate for COVID-19 pneumonia with renal complications.

Background
Some patients with COVID-19 pneumonia also present with kidney injury, and autopsy findings of patients who died from the illness sometimes show renal damage. However, little is known about the clinical characteristics of kidney-related complications, including hematuria, proteinuria, and AKI.

Methods
In this retrospective, single-center study in China, we analyzed data from electronic medical records of 333 hospitalized patients with COVID-19 pneumonia, including information about clinical, laboratory, radiologic, and other characteristics, as well as information about renal outcomes.

Results
We found that 251 of the 333 patients (75.4%) had abnormal urine dipstick tests or AKI. Of 198 patients with renal involvement for the median duration of 12 days, 118 (59.6%) experienced remission of pneumonia during this period, and 111 of 162 (68.5%) patients experienced remission of proteinuria. Among 35 patients who developed AKI (with AKI identified by criteria expanded somewhat beyond the 2012 Kidney Disease: Improving Global Outcomes definition), 16 (45.7%) experienced complete recovery of kidney function. We suspect that most AKI cases were intrinsic AKI. Patients with renal involvement had higher overall mortality compared with those without renal involvement (28 of 251 [11.2%] versus one of 82 [1.2%], respectively). Stepwise multivariate binary logistic regression analyses showed that severity of pneumonia was the risk factor most commonly associated with lower odds of proteinuric or hematuric remission and recovery from AKI.

Conclusions
Renal abnormalities occurred in the majority of patients with COVID-19 pneumonia. Although proteinuria, hematuria, and AKI often resolved in such patients within 3 weeks after the onset of symptoms, renal complications in COVID-19 were associated with higher mortality.
Florisztikai adatok a Tokaj–Zempléni-hegyvidékről és környékéről
Authors: Türke Ildikó Judit , Lontay László , Serfőző József , Zsólyomi Tamás , Drozd Attila , Pelles Gábor 
Published: April 2020

Cikkünkben a Tokaj–Zempléni-hegyvidék területéről és környékéről (a Szerencsközből, a Hernád-mentéről, a Bodrogközből, a Taktaközből és a Harangodból) az elmúlt évtized legfontosabb és legérdekesebb florisztikai eredményeiről számolunk be. A Zempléni-hegységből két új védett fajt (As­plenium javorkaeanum, Epipactis nordeniorum), a Bodrogköz magyarországi részéről pedig hét új védett fajt mutattunk ki (Cephalanthera damasonium, Cirsium brachycephalum, Epilobium palustre, Epipactis palustris, Lycopodium clavatum, Pyrola rotundifolia, Polystichum aculeatum). Számos ritka faj új lelőhe­lyére bukkantunk (Epipactis exilis, Dryopteris expansa, Blechnum spicant, Androsace maxima, Orchis cori­ophora, Orchis purpurea, Dactylorhiza sambucina, Sonchus palustris, Cicuta virosa). Továbbá sikerült megerősítenünk több olyan faj adatát, amelyek már évtizedek óta nem kerültek elő (Sedum hispanicum, Erysimum wittmannii subsp. pallidiflorum, Pseudolysimachion spurium, Botrychium lunaria).
Research on technological innovation model and performance analysis of new energy vehicles
Authors: Liu Wenting 
Published: April 2020

New energy vehicles are widely used in the transportation industry of various countries in the 21st century, which not only saves energy and protects environment, but also effectively promotes the development of China's transportation industry. At present, the main energy sources used by new energy vehicles are electric power and clean fuels. To ensure the normal running, attention should be paid to innovating technological modes and analyzing performance, which is the topic of this paper.
Prevalence of Advanced Chronic Kidney Disease in Patients with Nonvalvular Atrial Fibrillation Hospitalized in Cardiology Departments
Authors: Chashkina M. I. , Kozlovskaya N. L. , Andreev D. A. , Ananicheva N. A. , Bykova A. A. , Salpagarova Z. K. , Syrkin A. L. 
Published: April 2020

Objective.To estimate the prevalence of chronic kidney disease (CKD) 3b – 5 stages and the newly diagnosed sustained reduction in glomerular filtration rate (GFR) <30 ml / min / 1.73 m2 in patients with atrial fibrillation (AF) in real clinical practice, as well as the features of their anticoagulant therapy.Materials and Methods. Retrospectively, data of all discharge epicrisis from cardiological departments of five Moscow hospitals from June 1, 2016 to May 31, 2017 were analyzed. Patients over 18 years old with AF were enrolled. At the next stage, patients with CKD 3 b – 5 st and newly diagnosed sustained reduction in GFR <30 ml / min / 1.73 m2 (at least 2 measurements during hospitalization) were selected.Results.Data of 9725 patients were analyzed, AF was diagnosed in 2983 (31 %) cases, of which a decreased GFR <45 ml / min / 1.73 m2 was detected in 27 % (n = 794) cases. Among them, 349 (44 %) were diagnosed with CKD 3b st, 123 (15 %) with CKD 4 st, 44 (6 %) with CKD 5 st, 278 (35 %) had a newly diagnosed sustained reduction in GFR. In 63 % of patients with AF and GFR <45 ml / min / 1.73 m2, anemia was diagnosed, 39 % of them had moderate and severe one. 711 (89 %) patients were prescribed anticoagulants, 53 % were assigned direct oral anticoagulants (DOACs). Patients with CKD 3 b st. more often rivaroxaban 15 mg (29 %) was prescribed, with CKD 4 and CKD 5 – warfarin (48 % and 25 %, respectively), in patients with newly diagnosed sustained reduction in GFR <30 ml / min / 1.73 m2 – apixaban 10 mg / day (16.2 %).Conclusion.A quarter of patients with AF revealed a decreased GFR <45 ml / min / 1.73 m2, half of them were recommended DOACs. 42 % of patients with GFR <30 ml / min / 1.72 m2 were prescribed DOACs, 27 % – warfarin. Patients with CKD 5 st DOACs were not assigned; in half of cases, none of the anticoagulants was recommended. Most often, the dose of the prescribed anticoagulant was not counted according to GFR in patients with newly diagnosed sustained reduction in GFR <30 ml / min / 1.73 m2.
Prevalencia de diabetes mellitus gestacional en una población de Medellín de 1999 - 2000: valor predictivo positivo de la prueba tamiz y comparación de los criterios de la NDDG y la ADA
Authors: Cortés Y Hernán , Ocampo T Iván , Villegas P. Alberto 
Published: April 2020

INTRODUCCION: En 1997 la Asociación Americana de Diabetes (ADA), recomendó cambiar los criterios de tamización y diagnóstico para la diabetes gestacional, no tamizando a las pacientes de bajo riesgo y adoptando para el diagnóstico los criterios de Carpenter y Coustan.En nuestro medio no conocemos la incidencia de la diabetes, ni los niveles de riesgo.MÉTODOS: Se realizó una descripción prospectiva de pacientes gestantes que realizaron control prenatal de agosto de 1999 a julio de 2000, en el CAA central del ISS de la ciudad de Medellín; a todas estas se les realizó la prueba tamiz (prueba de O'Sullivan) entre las semanas 24-28 de la gestación y la prueba oral de tolerancia a las que lo requirieron.Se realizó una encuesta telefónica luego del parto para obtener los datos del resultado materno y neonatal.RESULTADOS: Se evaluaron 1726 pacientes de manera consecutiva, encontrando una prevalencia de diabetes gestacional de 1.43%, la cual aumentó a 2.03% cuando se aplicaron los nuevos criterios.Se determinó el valor predictivo positivo de la prueba tamiz, demostrando que no es diagnóstica con ningún valor.En cuanto al resultado neonatal el 20.5% de los bebés presentaron macrosomía, 13% en el grupo que cumplió los criterios de la NDDG y de 40% en los que cumplieron los de la ADA.CONCLUSIONES: En este grupo de pacientes se encontró una prevalencia baja de diabetes gestacional en comparación a poblaciones de otras regiones, no se logró demostrar que el adoptar los nuevos criterios mejore el pronóstico materno y neonatal; se deben realizar nuevos estudios que permitan una mejor selección de la población que se va a someter a la prueba tamiz para optimizar los recursos.
Manejo activo del alumbramiento con Misoprostol sublingual: un estudio clínico controlado en el Hospital de Maternidad Rafael Calvo de Cartagena
Authors: Angarita Peñaranda William , Borré Arrieta Orlando , Rodríguez Yances Benjamín 
Published: April 2020

OBJETIVOS: El objetivo del presente estudio es establecer la seguridad, eficacia y costos del Misoprostol sublingual, en el manejo activo del tercer periodo del parto.MATERIAL Y MÉTODOS: Se hace un estudio prospectivo, randomizado, controlado, donde se distribuyen 75 pacientes en tres grupos de 25 pacientes: A. Misoprostol sublingual, B. Oxitocina endovenosa, C. Metil-ergonovina postalumbramiento. Se cuantificó el sangrado durante la primera hora posparto y tiempo de alumbramiento. Se valoró el costo de los insumos utilizados en cada grupo, el comportamiento de los signos vitales antes y después del alumbramiento y los efectos colaterales de la droga en cada uno de los grupos.RESULTADOS: El sangrado en la primera hora posparto fue de 389cc ± 271.7 en el grupo de Misoprostol Vs 467cc ± 427.5 en el grupo de Oxitocina; Vs 546.8 ± 338.5 para el grupo de Metil-ergonovina postalumbramiento. Siendo estos resultados estadísticamente significativos p< 0.01. El tiempo de alumbramiento fue menor en el grupo de Misoprostol 308seg ± 57 Vs 362seg ± 162.3 con Oxitocina, Vs 557 seg ± 256.2 (p<0.05). Los costos con Misoprostol fueron de $500 Vs $8.000 con Oxitocina y $2.000 con Metil-ergonovina. No se presentaron efectos colaterales en ninguno de los grupos.CONCLUSIÓN: El Uso de 50mcgr de Misoprostol sublingual demostró ser seguro, eficaz y económico en el manejo del tercer periodo del parto.
NİGÎNÎ MECMUASINDAKİ FIKRALAR
Authors: KAVRUK Hasan , İÇLİ Ahmet 
Published: April 2020

İnsanoğlu,
yeryüzü macerasında iletişim kurduğu unsurlarla ilgili duygu ve düşüncelerini
farklı araçlarla dile getirir. Bunlardan birisi de hiç kuşkusuz edebiyattır.
Edebî metinlerde insanların acılarını, sevinçlerini, korkularını, kısacası
hayata dair tüm duygu ve düşüncelerini görmek mümkündür. Bu edebî metinlerden
birisi belki de en önemlisi fıkralardır. Fıkralar,
kısa ve özlü anlatımı olan nükteli ve güldürücü hikâyelerdir. Az sözle çok şey ifade
etme ve sezdirerek anlatma, fıkraların belirgin özellikleri arasındadır. Edebiyat
ile doğrudan veya dolaylı olarak ilgilenen kişilerin yazmış derlemiş oldukları
mecmualar, birçok yönden edebiyat ve tarih, hatta insanlığın tüm kültürel birikimleri
hakkında önemli bilgiler ihtiva ederler. Mecmualarda manzum veya mensur birçok sanat
özellikli metne rastlamak mümkündür. Klâsik Türk edebiyatında 17. yüzyılın ikinci
yarısı ile 18. yüzyılın ilk çeyreğinde yaşamış olan Nigînî Mehmed Çelebî’nin kendi
hattıyla yazdığı derleme eseri, birçok yönden önemli bir eserdir. Bu mecmuada Türk
Edebiyatındaki mizah geleneği bağlamında değerlendirilen latifeler/fıkralar da
önemli bir yer tutar. Mecmuada
“mutâyebe” başlığı altında verilen yetmiş üç latife/mizâhî anlatım/fıkra
vardır. Fıkraların tamamı mensurdur. Bu
çalışmada Nigînî Mehmed Çelebî’nin mecmuasında geçen fıkraların tasnifi
üzerinde durulmuştur.
ANALISIS BATAS PENAMBANGAN OPTIMAL BATUBARA MENGGUNAKAN METODE ALGORITMA LERCHS-GROSSMAN 2D PADA PT METALINDO BUMI RAYA
Authors: Wiwin Wendly , Nurhakim Nurhakim , Riswan Riswan 
Published: April 2020

PT Metalindo Bumi Raya telah melakukan penentuan pit limit dengan metode yang telah disetujui untuk menjadi acuan dalam penentuan pit limit tersebut. Penelitan ini bertujuhan untuk membuat disain pit limit dengan metode yang berbeda dengan yang digunakan oleh perusahan.Desain pit limit ditentukan dengan bantuan software yaitu Minescape dan excel. Penentuan batas pit limit bertujuan untuk menentukan seberapa efisiensinya dengan menggunakan metode algoritma Lerchs-Grossman apa layak untuk ditambang atau tidak.Dari hasil penelitain didapat pit limit dengan metode algoritma Lerchs-Grossman yaitu pada blok utara harga kumulatif tertinggi yaitu pada 4421 USD. Sedangkan tonase batubara yaitu 149 blok dan tonase Ob yaitu 152 blok, sedangkan pada blok selatan tidak efisen dilakukan proses penambangan dengan metode algoritma Lerchs-Grossman karna setiap bloknya bernilai negatif. Kata-kata kunci: Pit limit, Algoritma Lerchs-Grossman, Biaya, Harga