bluuebunny/crossref_metadata_2025_split huggingface dataset:
Work on structural integrity for semi submersibles exposed to bergy bits – integrated analysis of ice structure impacts
Authors: Lu W , Yu Z , Van D Berg M , Lubbad R , Kim E , Amdahl J , Bjørheim L G , Langøy M A , Løset S 
Published: November 2019

Abstract
Bergy bits and growlers (i.e., glacial ice features with a waterline diameter < 15 m) travelling with waves are identified as risk to the integrity of offshore structure and ships operating in the high North. It is generally more difficult to detect and monitor these small ice features and apply concurrent ice management operations. Therefore, it is important to study the corresponding damage assessment of a potential impact with such glacial ice features. Traditionally, while carrying out a structural damage assessment, the ice feature is often treated as a rigid body, whereas structural deformation and fractures are simulated with, e.g., NonLinear Finite Element Method (NLFEM). However, this method is too conservative and neglects that the ice feature crushes and dissipates part of the impact energy (often obtained with the so-called external mechanics). On the other hand, it is possible to treat both the ice and the structure deformable, and a fully coupled simulation can be carried out with NLFEM. This method can capture the physical essence that the impact energy dissipation is shared by both ice crushing and structural deformation, thus leading to a less conservative structural damage assessment. However, this method is often too computationally expensive and can only take care of the so-called ‘internal mechanics’ part. In this paper, we propose an integrated approach. This approach is mainly based on the innovative Simulator for Arctic Marine Structures (SAMS) to calculate the impact energy following the principle of ‘external mechanics’. Afterwards, the simulated results are integrated with NLFEM simulations to re-construct the shared impact energy dissipation between both the ice feature and structure. A case study regarding a glacial ice feature (diameter = 15 m) impacting a semi-submersible is carried out in this paper. This integrated simulation approach (i.e., SAMS + NLFEM) is proved to be significantly more effective than the fully coupled analysis; more versatile and less conservative than the limiting scenario analysis when dealing with the impact between ice features and man-made structures.
A summary of adapting Industry 4.0 vision into engineering education in Azerbaijan
Authors: Ahadov A , Asgarov E S , El-Thalji I 
Published: November 2019

Abstract
Industry 4.0 vision and associated technologies are rapidly adopted in several industrial sectors to gain the benefits of creating smart cyber-physical systems and operations. Some sectors, e.g. manufacturing, oil and gas, offshore wind energy, have progressed in developing digitization strategies, executing pilot projects and progressing toward mature implementation of industry 4.0 vision. Offshore Oil and Gas industry highly believes in the potential industrial and societal impacts of digital transformation, due to the need for stochastic and remote operations. Azerbaijan as one of the countries that heavily depend on the Oil and Gas industry is developing more projects in the Caspian Sea. There are several worldwide challenges, mainly, lack of standards, business models, ready products/services and competent and skilled employees. Fortunately, specific developed countries are working hard to standardize industry 4.0 architecture. Moreover, large-scale companies are creating alliances to create a trustful and long-term business model. Furthermore, large-scale companies of information and operational technology are creating robust products and services to be commercially available off the shelf. In terms of education and training, many worldwide universities are upgrading their programs, curriculums, teaching approaches with the goal to support the industry with competent future employees and entrepreneurs. Therefore, the purpose of this paper is, to present the status of engineering education programs in adapting the industry 4.0 vision in Azerbaijan and address the skills that are required for future employment. In order to present the targeted status, the curriculums of all engineering education programs at the master level were collected and analyzed. However, five of them were directly adapting industry 4.0 vision and relevant for industry 4.0. Moreover, a semi-structured interview with industrial managers was applied to extract the future required skills. This study can be considered as a first step in developing a roadmap for engineering education, particularly industrial engineering, to adopt industry 4.0 vision at the national level.
Context analysis of Offshore Fish Farming
Authors: El-Thalji I 
Published: November 2019

Abstract
The in-land and nearshore fish farming is facing capacity limitation and onshore push-out regulations. Huge technological innovations are rapidly evolving toward developing competitive Offshore fish farming. These technological innovations are mainly targeting to innovate new farming concepts that dynamically stable, reliable and compatible with offshore environmental loads and conditions. The dynamic operational behaviour of each farming concept is quite complicated. It is a combination of reinforcing behaviours (Loads, cage deformations, welfare issues, e.g. escaping, stress-related disease) and leveraging behaviours (Biofouling-cleaning, Deterioration-maintenance) and all influenced by fluctuating and harsh environmental loads and conditions. Therefore, the purpose of this paper is to analyse the context of offshore fish farming and explore quantitative descriptions of its reinforcement and leveraging behaviours. The context analysis is a well-known method within systems engineering methodology to illustrate and extract critical interfaces. The context analysis is considered as the first step in building simulation model to quantify the impact of systems interfaces on the entire farming economics, i.e. income and cost.
Development and characterization of jute composites for sustainable product: effect of chemical treatments and polymer coating
Authors: Yadav Arun , Gupta M K 
Published: November 2019

Abstract
In this work, woven jute fibres were subjected to ecofriendly and chemical treatments (alkali, benzoylation and sodium bicarbonate) and PLA coating in order to improve the adhesion with epoxy thereby improvement in the performances of their composites. Treated and coated jute fibres reinforced epoxy composites were prepared by hand lay-up technique keeping constant 30 wt% of fibres content in the each composite. Mechanical properties (i.e. tensile, flexural and impact) and dynamic mechanical properties (i.e. storage modulus, loss modulus, damping and glass transition temperature) of prepared composites were studied. The outcomes from the experimental results suggested that benzoyl chloride treated and PLA coated jute composite exhibited the best performance as compared to other all the composites. There were 21%, 40.6% and 27.5% improvement in tensile strength, flexural strength and impact strength respectively for this composite as compared to that of untreated jute fibre reinforced composites. Moreover, storage and loss modulus of jute composites were also significantly enhanced by treatment and coating. The present developed composites can be used for medium strength application in the field of automobile, building and construction and packaging.
An exploration of the freeform two-mirror off-axis solution space
Authors: Volatier Jean-Baptiste , Duveau Louis , Druart Guillaume 
Published: November 2019

Abstract
We use a differential construction procedure to construct three starting solutions for a thermal infrared telescope design problem. We further refine these solutions with a simple optimization procedure. We show that this hybrid method is interesting by its flexibility that makes it suitable to find solutions to problems with tight volume constraints and its ease of use with little designer interaction required. Taking advantage of a fully automated process, we are able to investigate for each solution and its starting geometry, the impact of the Zernike order on the final performance obtained. Finally we show the systems proposed are sufficient for thermal infrared applications and while not as performant as the three mirror system used for comparison, their simplicity makes them an interesting alternative.
Arabidopsis halleri: a perennial model system for studying population differentiation and local adaptation
Authors: Honjo Mie N , Kudoh Hiroshi 
Published: November 2019

AbstractLocal adaptation is assumed to occur when populations differ in a phenotypic trait or a set of traits, and such variation has a genetic basis. Here, we introduce Arabidopsis halleri and its life history as a perennial model system to study population differentiation and local adaptation. Studies on altitudinal adaptation have been conducted in two regions: Mt. Ibuki in Japan and the European Alps. Several studies have demonstrated altitudinal adaptation in ultraviolet-B (UV-B) tolerance, leaf water repellency against spring frost and anti-herbivore defences. Studies on population differentiation in A. halleri have also focused on metal hyperaccumulation and tolerance to heavy metal contamination. In these study systems, genome scans to identify candidate genes under selection have been applied. Lastly, we briefly discuss how RNA-Seq can broaden phenotypic space and serve as a link to underlying mechanisms. In conclusion, A. halleri provides us with opportunities to study population differentiation and local adaptation, and relate these to the genetic systems underlying target functional traits.
Extra-pair mating opportunities mediate parenting and mating effort trade-offs in a songbird
Authors: Lv Lei , Zhang Zhengwang , Groenewoud Frank , Kingma Sjouke A , Li Jianqiang , van der Velde Marco , Komdeur Jan 
Published: November 2019

Abstract
In socially monogamous species with bi-parental care, males may face a trade-off between providing parental care and pursuing extra-pair matings. The “parenting-mating trade-off” hypothesis predicts that high-quality males—who have greater potential to gain extra-pair matings, for example, larger males usually win the competition for extra-pair mating—should reduce parental care and spend more time looking for extra-pair matings. However, the trade-off between parenting and mating efforts may be complicated by variation in the availability of extra-pair mating opportunities. By using field data of hair-crested drongos (Dicrurus hottentottus), a species exhibiting bi-parental incubation behavior, collected in central China from 2010 to 2017, we tested whether the potential negative relationship between male quality and paternal care was dependent on the number of nearby fertile females. We found that male drongos mainly seek extra-pair matings during the incubation period and high-quality individuals (males with longer tarsi) are more likely to sire extra-pair offspring. In agreement with the “parenting-mating trade-off” hypothesis, high-quality males incubated less by recessing longer between incubation bouts. However, this was only the case when sufficient fertile females nearby for extra-pair mating opportunities. Females compensated for reduced male care, but this was independent of male quality. This suggests that the reduction in care by high-quality males might be a direct response to extra-pair mating opportunities rather than facilitated by differential allocation of females. Our results indicate that individual quality and available mating opportunities may shape the optimal trade-off between parental care and seeking additional matings for males.
Morphological and physiological consequences of a dietary restriction during early life in bats
Authors: Meniri Magali , Hebinger Doriane , Sorlin Mahaut , Ramirez Marine , Kauffmann Emilie , Vallat Armelle J , Glauser Gaëtan , Fasel Nicolas , Helfenstein Fabrice 
Published: November 2019

Abstract
Early life adverse conditions can have major consequences on an individual’s life history traits. Oxidative stress has been hypothesized to be one main mechanism underlying the negative consequences of early life adverse conditions. To test this hypothesis, we restricted the food availability of Seba’s short-tailed bat (Carollia perspicillata) mothers of unweaned pups for 10 days, followed by ad libitum provisioning. We also had a control, unrestricted group. We explored the morphological consequences of dietary restriction during early life by measuring growth rate. We also measured four markers of blood oxidative balance during growth. We assessed the level of cortisol, and its inactive form cortisone, in the hair of the pups at the end of growth. Finally, we monitored survival during the first year. Food restriction triggered a slowdown in growth followed by catch-up growth when ad libitum feeding was restored which did not lead to full compensation in size or mass compared to control individuals. We found that higher growth rate was associated with elevated oxidative damage, suggesting an oxidative cost to growth. However, we found no clear evidence for physiological costs specific to the catch-up growth. Survival after a year was not impacted by the treatment, the oxidative balance or the level of glucocorticoids at the end of growth. In conclusion, our results show that individuals were able to efficiently mitigate the short-term consequences of adverse early life conditions. However, consequences might arise in the long-term, and could impact reproductive success or lifespan.
Organoid model of mammographic density displays a higher frequency of aberrant colony formations with radiation exposure
Authors: Cheng Qingsu , Parvin Bahram 
Published: November 2019

Abstract

Motivation
Aberrant three-dimensional (3D) colony organization of premalignant human mammary epithelial cells (HMECs) is one of the indices of dysplasia. An experiment has been designed where the stiffness of the microenvironment, in 3D culture, has been set at either low or high level of mammographic density (MD) and the organoid models are exposed to 50 cGy X-ray radiation. This study utilizes published bioinformatics tools to quantify the frequency of aberrant colony formations by the combined stressors of stiffness and X-ray exposure. One of the goals is to develop a quantitative assay for evaluating the risk factors associated with women with high MD exposed to X-ray radiation.

Results
Analysis of 3D colony formations indicate that high stiffness, within the range of high MD, and X-ray radiation have an approximately additive effect on increasing the frequency of aberrant colony formations. Since both stiffness and X-ray radiation are DNA-damaging stressors, the additive effect of these stressors is also independently validated by profiling activin A-secreted protein. Secretion of activin A is known to be higher in tissues with a high MD as well as tumor cells. In addition, we show that increased stiffness of the microenvironment also induces phosphorylation of γH2AX-positive foci. The study uses two HMECs derived from a diseased tissue (e.g. MCF10A) and reduction mammoplasty of normal breast tissue (e.g. 184A1) to further demonstrate similar traits in the frequency of aberrant colony organization.

Supplementary information
Supplementary data are available at Bioinformatics online.
Social Workers under the Spotlight: An Analysis of Fitness to Practise Referrals to the Regulatory Body in England, 2014–2016
Authors: Banks Sarah , Zasada Magdalena , Jago Robert , Gallagher Ann , Austin Zubin , van der Gaag Anna 
Published: November 2019

Abstract
This article examines the nature of, and reasons for, the disproportionately high rates of fitness to practise referrals of social workers in England to the Health and Care Professions Council (HCPC), compared with other professions regulated by HCPC during 2014–2016. In 2014–2015, the rate of referrals for social workers was 1.42 per cent of registrants, compared with an average for the sixteen professions regulated by HCPC of 0.66 per cent. Drawing on published statistics and unique analysis of a sample of 232 case files undertaken as part of a research project in 2016–2017, the article highlights relatively high rates of inappropriate referrals from ‘members of the public’ (mainly service users) particularly in relation to child placements and contact. A detailed picture is offered of the variety of referrals dealt with at each stage of the fitness to practise process (from initial triage to final hearings), with recommendations for how to prevent inappropriate referrals, whilst focusing concern on the most serious cases of incompetence and misconduct. This research is of significance at a time of increasing pressure for social workers, social services and service users under conditions of austerity and managerialism; on-going concerns about standards in social work; and recent changes in social work regulation.
Reduced drift rate: a biomarker of impaired information processing in functional movement disorders
Authors: Sadnicka Anna , Daum Corinna , Meppelink Anne-Marthe , Manohar Sanjay , Edwards Mark 
Published: November 2019

Abstract
Functional neurological disorder is a common and phenomenologically diverse condition. Resultant disability is caused by both the dominant clinical presentation, e.g. paralysis or tremor and additional symptomatology such as cognitive symptoms. Recently the similarity of neuropsychiatric profiles across a range of functional syndromes has been highlighted. This is suggestive of a common underlying mechanism with a theoretical deficit of information processing proposed. Identification of an experimental biomarker for such deficits could offer novel assessment and therapeutic strategies. In this study, we took the temporal discrimination threshold as a paradigm that can be used to model sensory processing in functional movement disorders. Our hypothesis was that we would be able to delineate markers of slowed information processing in this paradigm removed from the phenomenological presentation with a movement disorder. We recorded both response accuracy and reaction time in a two-choice temporal resolution/discrimination task in 36 patients with functional movement disorders and 36 control subjects. A psychometric function was fitted to accuracy data for each individual revealing both abnormally high threshold values (P = 0.0053) and shallow psychometric slopes in patients (P = 0.0015). Patients with functional movement disorders also had significantly slower response times (P = 0.0065). We then used a well-established model for decision-making (the drift diffusion model) that uses both response accuracy and reaction time data to estimate mechanistic physiological dimensions of decision-making and sensory processing. This revealed pathologically reduced drift rate in the patient group, a parameter that quantifies the quality and rate of information accumulation within this sensory task (P = 0.002). We discuss how the deficits we observed in patients with functional movement disorders are likely to stem from abnormal allocation of attention that impairs the quality of sensory information available. Within a predictive coding framework sensory information could be down-weighted in favour of predictions encoded by the prior. Our results therefore offer a parsimonious account for a range of experimental and clinical findings. Reduced drift rate is a potential experimental marker for a generalized deficit in information processing across functional disorders that allows diverse symptomatology to be quantified under a common disease framework.
Associating Psychotic Symptoms with Altered Brain Anatomy in Psychotic Disorders Using Multidimensional Item Response Theory Models
Authors: Stan Ana D , Tamminga Carol A , Han Kihwan , Kim Jong Bae , Padmanabhan Jaya , Tandon Neeraj , Hudgens-Haney Matthew E , Keshavan Matcheri S , Clementz Brett A , Pearlson Godfrey D , Sweeney John A , Gibbons Robert D 
Published: November 2019

Abstract
Reduced cortical thickness has been demonstrated in psychotic disorders, but its relationship to clinical symptoms has not been established. We aimed to identify the regions throughout neocortex where clinical psychosis manifestations correlate with cortical thickness. Rather than perform a traditional correlation analysis using total scores on psychiatric rating scales, we applied multidimensional item response theory to identify a profile of psychotic symptoms that was related to a region where cortical thickness was reduced. This analysis was performed using a large population of probands with psychotic disorders (N = 865), their family members (N = 678) and healthy volunteers (N = 347), from the 5-site Bipolar-Schizophrenia Network for Intermediate Phenotypes. Regional cortical thickness from structural magnetic resonance scans was measured using FreeSurfer; individual symptoms were rated using the Positive and Negative Syndrome Scale, Montgomery-Asberg Depression Rating Scale, and Young Mania Rating Scale. A cluster of cortical regions whose thickness was inversely related to severity of psychosis symptoms was identified. The regions turned out to be located contiguously in a large region of heteromodal association cortex including temporal, parietal and frontal lobe regions, suggesting a cluster of contiguous neocortical regions important to psychosis expression. When we tested the relationship between reduced cortical surface area and high psychotic symptoms we found no linked regions describing a related cortical set.
Liver Fibrosis Progression and Mortality in Hepatitis B– and C–Coinfected Persons Treated With Directly Acting Antiviral Agents: Results From ERCHIVES
Authors: Butt Adeel A , Yan Peng , Aslam Samia , Abou-Samra Abdul-Badi , Sherman Kenneth E , Shaikh Obaid S 
Published: November 2019

Abstract
For persons with baseline Fibrosis-4 1.46–3.25, cirrhosis incidence/1000 patient-years was 49.3 among hepatitis B virus (HBV)/hepatitis C virus (HCV) coinfected and 18.2 among HCV monoinfected (P = .03). Cirrhosis risk was numerically higher but statistically nonsignificant among HBV/HCV coinfected (hazards ratio [HR] 1.51; 95% confidence intervals [CI], .37–6.05) but lower among those who attained sustained virologic response (HR, .52; 95% CI, .42–.63).
Long-Term Sequelae and Health-Related Quality of Life Associated With Lyme Disease: A Systematic Review
Authors: Mac Stephen , Bahia Simran , Simbulan Frances , Pullenayegum Eleanor M , Evans Gerald A , Patel Samir N , Sander Beate 
Published: November 2019

AbstractLyme disease (LD) is the most commonly reported vector-borne disease, but its clinical consequences remain uncertain. We conducted a systematic review of the long-term sequelae and health-related quality of life (HRQoL) associated with LD in North America and Europe. We performed searches in 6 electronic databases up to December 2018 following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, including observational studies reporting long-term sequelae, HRQoL, and prognostic factors. We included 46 studies, published between 1994 and 2019. Based on 21 studies reporting attributable outcomes, higher proportions of sequelae reported from exposed patients were: neck pain, myalgia, arthralgia, paresthesia, sleep disorder, poor appetite, and concentration difficulties. Patients with PTLDS reported impaired HRQoL compared to the general US population. Included studies were highly heterogeneous in terms of study design, settings, patient characteristics, and quality. Patients with LD are more likely to report nonspecific long-term sequelae, especially those experiencing persistent symptoms posttreatment. Opportunities exist for prospective longitudinal studies to better understand LD outcomes.