bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of influent temperature variation on floc blanket behavior and effluent water quality
Authors: Illangasinghe Wasantha , Manatunge Jagath , Ratnayake Niranjanie , Jayasuriya Niranjali 
Published: June 2020

Abstract
The temperature of the water in clarifier tanks has been shown to have a significant influence on floc blanket stability. The objective of this research was to determine the effects of variations in the influent temperature on a floc blanket using laboratory and field experiments and to assess whether the cohesivity of the blanket expressed as the sludge cohesion coefficient (SCC) can be used to interpret the effect of temperature variations. Effluent turbidity exhibited a strong positive correlation with inflow temperature during the increasing temperature phase and a strong negative correlation during the temperature recession phase. An increment of 2 °C in the influent temperature caused the effluent turbidity to increase by 1 NTU. The SCC of the blanket exhibited a significant relationship with the influent temperature. The optimum blanket cohesivity (SCC of 0.7 mm/sec) was observed at a temperature of 23.2 °C, above which the cohesivity decreased. At higher temperatures, frequent particle collisions owing to high inertial forces cause particle motion with the upward flow and increase the effluent turbidity. No correlation between SCC and blanket settling velocity was observed.
Effects and Mechanisms of Anlotinib and Dihydroartemisinin Combination Therapy in Ameliorating Malignant Biological Behavior of Gastric Cancer Cells
Authors: Luo Qiong , Zhang Suyun , Zhang Donghuan , Feng Rui , Li Nan , Chen Wujin , Chen Xiangqi , Yang Sheng 
Published: June 2020

Background:
Gastric Cancer (GC) is currently one of the major malignancies that threaten
human lives and health. Anlotinib is a novel small-molecule that inhibits angiogenesis to exert antitumor
effects. However, its function in gastric cancer is incompletely understood.

Objective:
The aim of the present study was to investigate the anti-tumor effects and molecular mechanisms
of anlotinib combined with Dihydroartemisinin (DHA) in SGC7901 gastric cancer cells.

Methods:
Different concentrations of anlotinib and DHA were used to treat SGC7901 gastric cancer
cells, after which cell proliferation was measured. Drug interactions of anlotinib and DHA were analyzed
by the Chou-Talalay method with CompuSyn software. Proliferation, apoptosis, invasion, migration,
and angiogenesis were measured using the Cell Counting Kit-8 (CCK8) assay, flow cytometry,
Transwell invasion assays, scratch assays, and chicken Chorioallantoic Membrane (CAM) assays. Proliferation-
associated protein (Ki67), apoptosis-related protein (Bcl-2), and Vascular Endothelial
Growth Factor A (VEGF-A) were quantified by Western blotting.

Results:
The combination of 2.5 μmol/L of anlotinib and 5 of μmol/L DHA was highly synergistic in inhibiting cell growth,
significantly increased the apoptosis rate and suppressed obviously the invasion and migration capability and angiogenesis
of gastric cancer cells. In addition, the expression levels of Ki67, Bcl-2, and VEGF-A, as well as angiogenesis, were significantly decreased in the Combination of drugs compared with in control and either drug alone.

Conclusion:
The combination of anlotinib and DHA showed synergistic antitumor activity, suggesting
their potential in treating patients with gastric cancer.
Unravelling the Role of Rhizospheric Plant-Microbe Synergy in Phytoremediation: A Genomic Perspective
Authors: Agarwal Priyanka , Giri Balendu Shekher , Rani Radha 
Published: June 2020

Background:
Accretion of organic and inorganic contaminants in soil interferes in the food
chain, thereby posing a serious threat to the ecosystem and adversely affecting crop productivity and
human life. Both endophytic and rhizospheric microbial communities are responsible for the biodegradation
of toxic organic compounds and have the capability to enhance the uptake of heavy metals by
plants via phytoremediation approaches. The diverse set of metabolic genes encoding for the production
of biosurfactants and biofilms, specific enzymes for degrading plant polymers, modification of
cell surface hydrophobicity and various detoxification pathways for the organic pollutants, plays a
significant role in bacterial driven bioremediation. Various genetic engineering approaches have been
demonstrated to modulate the activity of specific microbial species in order to enhance their detoxification
potential. Certain rhizospheric bacterial communities are genetically modified to produce specific
enzymes that play a role in degrading toxic pollutants. Few studies suggest that the overexpression
of extracellular enzymes secreted by plant, fungi or rhizospheric microbes can improve the degradation
of specific organic pollutants in the soil. Plants and microbes dwell synergistically, where microbes
draw benefit by nutrient acquisition from root exudates whereas they assist in plant growth and
survival by producing certain plant growth promoting metabolites, nitrogen fixation, phosphate solubilization,
auxin production, siderophore production, and inhibition or suppression of plant pathogens.
Thus, the plant-microbe interaction establishes the foundation of the soil nutrient cycle as well as decreases
soil toxicity by the removal of harmful pollutants.

Conclusion:
The perspective of integrating genetic approach with bioremediation is crucial to evaluate
connexions among microbial communities, plant communities and ecosystem processes with a focus
on improving phytoremediation of contaminated sites.
Risk Reduction and Prevention of Alzheimer's Disease: Biological Mechanisms of Diet
Authors: McGurran Hugo , Glenn Jordan , Madero Erica , Bott Nick 
Published: June 2020

:
Alzheimer’s Disease (AD) incidence is increasing and with no disease modifying agents
available, preventative measures through lifestyle factors are being investigated. Combined with the
prevention of AD risk factors such as heart disease, diabetes, and with more recent evidence, microbiome
dysfunction, there is a substantial foundation for diet as a modifiable risk factor and preventative
measure for AD. Recent evidence suggests AD associated pathologies, such as oxidative stress and inflammation,
can be modulated by the lipids, vitamins, and polyphenols obtained through nutritional intake.
Furthermore, epidemiological and preclinical evidence has uncovered certain compounds within
foods that may have beneficial effects in the prevention of AD, including omega-3 fatty acids, vitamin
E, and resveratrol among others. However, clinical data examining specific compounds are often inconsistent
and fail to replicate the preclinical data. On the other hand, dietary patterns such as the Mediterranean
or MIND diet have shown promise in terms of clinical outcomes for patients, indicating a reductionist
approach to diet is not as effective as a holistic dietary pattern. In this review, we summarize
some of the biological mechanisms of key compounds in their relation to AD and how they fit into a
dietary pattern that supports the role of diet as a risk reducing factor for AD.
Neuroimaging Outcomes in Studies of Cognitive Training in Mild Cognitive Impairment and Early Alzheimer’s Disease: A Systematic Review
Authors: Beishon Lucy , Intharakham Kannakorn , Swienton David , Panerai Ronney B. , Robinson Thompson G. , Haunton Victoria J. 
Published: June 2020

Background:
Cognitive Training (CT) has demonstrated some benefits to cognitive and psychosocial
function in Mild Cognitive Impairment (MCI) and early dementia, but the certainty related to
those findings remains unclear. Therefore, understanding the mechanisms by which CT improves cognitive
functioning may help to understand the relationships between CT and cognitive function.
The purpose of this review was to identify the evidence for neuroimaging outcomes in studies of CT in
MCI and early Alzheimer’s Disease (AD).

Methods:
Medline, Embase, Web of Science, PsycINFO, CINAHL, and The Cochrane Library were
searched with a predefined search strategy, which yielded 1778 articles. Studies were suitable for inclusion
where a CT program was used in patients with MCI or AD, with a structural or functional Magnetic
Resonance Imaging (MRI) outcome. Studies were assessed for quality using the Downs and Black criteria.

Results:
Medline, Embase, Web of Science, PsycINFO, CINAHL, and The Cochrane Library were
searched with a predefined search strategy, which yielded 1778 articles. Studies were suitable for inclusion
where a CT program was used in patients with MCI or AD, with a structural or functional Magnetic
Resonance Imaging (MRI) outcome. Studies were assessed for quality using the Downs and Black criteria.

Conclusions:
CT resulted in variable functional and structural changes in dementia, and conclusions are
limited by heterogeneity and study quality. Larger, more robust studies are required to correlate these
findings with clinical benefits from CT.
Adolescent Inpatients with Depression: Comparison to Inpatients without Depression and to Peers without Psychiatric Disorders
Authors: Savilahti Emma M. , Rytilä-Manninen Minna , Haravuori Henna , Marttunen Mauri 
Published: June 2020

Background:
Family background, social support and psychological characteristics
are known to be associated with depression in adolescence, but scientific data in complex,
naturalistic settings are scarce.

Objective:
To investigate the characteristics of adolescent psychiatric inpatients with depressive
disorders compared to peers without psychiatric disorders and to adolescent psychiatric
inpatients without depression.

Methods:
The study population of 206 inpatients (13-17 years old) and 203 age and gendermatched
non-referred adolescents was evaluated using the Schedule for Affective Disorders
and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL) interview,
and clinical interview and clinical records when available. Structured self-reports
provided information on family background, defense styles, self-image and perceived social
support. We compared firstly subjects with current depressive disorders (n=120) to subjects
without any psychiatric disorder (n=159) and secondly within the inpatient population, those
with depressive disorders (n=117) to those with any other psychiatric diagnoses (n=89).

Results:
Current depressive disorders were characterized by worse self-image, less mature
defenses and less perceived social support particularly from the family. Adversities in the
family were more prevalent in subjects with depression compared to subjects without any
psychiatric diagnosis, while among inpatients, no significant differences were observed.
Psychiatric comorbidity was common in all inpatients, whereas suicidality was more prevalent
among inpatients with depression.

Conclusions:
Negative self-image, less mature defense style and low perceived social support
particularly from the family were characteristics of depression in adolescents.
A Blockchain Based Buyer-seller Watermark Protocol with Trustless Third Party
Authors: Song Chunlin , Wang Hong , Zhang Wei , Sudirman Sud , Zhu Haogang 
Published: June 2020

Background:
With the development and innovation of digital information technologies
and new-generation Internet information platforms, new types of information exchange methods
have been spawned. It has broken the restriction of the traditional internet boundary, and integrated
all round connections between people and objects.

Methods:
Based on the above progresses, digital multimedia contents distributed or published much
more convenient on the internet than before and most of them without any copyright protection. The
dishonest owner can easily copy and distribute digital multimedia content without reducing any perceptual
quality. According to the relative concerns, watermark protocol networks play a very important
role in the usage tracking and copyrights infringement authentication, etc. However, most of
the watermark protocols always require a “fully trusted third party”, which has a potential risk to
suffer conspiracy attack.

Results:
Therefore, in this paper, we focus on designing a watermark protocol with trustless third
party via blockchain for protecting copyrights of owners that they want to publish or distribute on
the internet. The proposed watermark protocol includes three sub-protocols which covers the negotiation
process, transaction process and identification processes.

Conclusion:
In addition, this paper also provides a fully detail analysis that describes the benefits
and weaknesses of current solution.
Examining Social Capital, Social Support, and Language Use in an Online Depression Forum: Social Network and Content Analysis
Authors: Pan Wenjing , Feng Bo , Shen Cuihua 
Published: June 2020

BackgroundThe use of peer-to-peer online support groups and communities has grown into a social phenomenon. Many people use online support groups and communities to seek and provide social support. It is essential to examine how users’ participation behaviors may contribute to different outcomes.ObjectiveThis study aimed to (1) use the structural positions of online depression forum users in their reply network to predict received support and (2) examine their language use reflecting their health conditions.MethodsA total of 2061 users and their 62,274 replies posted on a depression forum from July 2004 to July 2014 were extracted using a web crawler written in Python. The content of the forum users’ posts and replies and their reply patterns were examined. A social network analysis method was used to build the reply networks of users. The computerized text analysis method was used to measure features of the forum users’ language styles.ResultsForum users’ bridging social capital (operationalized as network betweenness) was positively associated with the level of communication accommodation in their received replies (P=.04). Forum users’ bonding social capital (operationalized as network constraint) was negatively associated with the level of communication accommodation in their received replies (P<.001). The forum users’ change in their use of self-referent words and words expressing negative emotions were examined as linguistic proxies for their health conditions and mental states. The results revealed a general negative association between the number of received replies and the degree of decrease in the use of words expressing negative emotion (P=.007).ConclusionsThe structural positions of online depression forum users in the reply network are associated with different participation outcomes in the users. Thus, receiving replies can be beneficial to online depression forum users.
Koleksi buku cerita bergambar (picture storybooks) di Perpustakaan Desa Sukamukti
Authors: Yusup Pawit M. , Rachmawati Tine Silvana , Damayani Ninis Agustini , Rukmana Evi Nursanti 
Published: June 2020

Introduction. The teachers at Kelompok Belajar Islam Terpadu (KBIT) Sukamukti village have used picture storybooks from the Library of Sukamukti village and reading them in a story telling session to their students. Two of this activities as a basic in the pre-reading activity to early childhood, so that the purpose this reaserch is to understand how the teachers use the picture storybooks, reading technique, and storytelling.
Data Collection Method. This paper used a qualitative perspective with phenomenology by using observations, interviews, focus group discussions, and literature study.
Analysis Data. Data from interviews were transcribed for further analysis
Results and Discussion. The teachers at KBIT Sukamukti village used the picture of storybooks with fables. The teachers also discussed plot, animal activities, themes and morality based on the story. The language in the story is easy to understand by the children, book illustrations explain the reality of the character in the forest. Activities read aloud by introducing the identity of the book used, and storytelling activities through self-assement, stories, sounds, expressions, gestures, and other abilities.
Conclusion. The teachers read and tell stories to educate young children in alphabet, vocabularies, and creativity. This helps early children in the process of learning pre-reading.
Analisis Pengaruh Perubahan Kerapatan Vegetasi Terhadap Suhu Permukaan Karena Kegiatan Pertambangan Menggunakan Citra Satelit Multiwaktu (studi kasus: PT. AMMAN MINERAL NUSA TENGGARA)
Authors: Putra Bayu Wisnu , Djurdjani Djurdjani 
Published: June 2020

PT.Amman Mineral Nusa Tenggara (PT.AMNT) is an Indonesian mining company that operates the Batu Hijau mine. Mining activities can cause a decrease in vegetation cover and can have an impact on increasing surface temperature. This study aims to determine how the impact of mining activities on vegetation density and surface temperature. The change in vegetation density and surface temperature in the mining area can be detected by processing of remote sensing satellite imagery with different data recording times. The data used are five Landsat satellite imagery in 1998, 2004, 2008, 2014 and 2018. Vegetation index extraction process is carried out using the NDVI (Normalized Difference Vegetation Index) formula. While surface temperature extraction process is carried out using the Mono-window Brightness Temperature method. The results of the extraction process are then used to analyze the effect of vegetation density changes on surface temperature. The results of this study indicate that the vegetation density in the mining area has decreased and the average surface temperature has increased. The results of the correlation analysis showed that the decrease in the level of vegetation density caused the increase in surface temperature in the mining area of PT.AMNT.
Pemanfaatan Citra Side Scan Sonar untuk Identifikasi Objek Bawah Laut
Authors: Prayetno Eko , Ulinnuha Hilmiyati 
Published: June 2020

Lamong Bay waters are part of the Port of Tanjung Perak Surabaya. This port is included in one of the busiest ports in Indonesia. Therefore, a study is needed on the condition of the bottom waters and underwater infrastructure buildings to provide information on the safety of the shipping lanes and the landing of the lego anchor on the position of the underwater infrastructure. This study involves exploration activities such as the detection and sweeping of objects at the bottom of the sea and taking sediment samples using side scan sonar instruments and van veen grab sampler. This activity aims to identify the condition of objects of sea cables and pipelines in the waters of the Lamong Bay waters, evaluating the rules of immersion of submarine cables and pipelines in accordance with the Minister of Transportation Regulation No. PM 129 of 2016. The results of this activity will be in the form of a map of sea cables and sea pipes which will be attached to the Lamong Bay Field Painting Sheet. The submarine cable target recorded is in Line A with the cable target detected 2 (two) cable lines. Whereas the sea pipe is located at Lane B. The results of the inspection are to be placed on the Indonesian Sea Map No. 84 to determine the position of sea cables and pipelines. Each of the submarine cable and pipelines target was analyzed by Minister of Transportation Regulation No. PM 129 of 2016 concerning the regulation of immersion of underwater buildings. The results of the submarine cable and pipelines analysis have met the installation standards even though they are at a shallow depth. This suitability is seen based on dictum 2 (two) rules of burial that burials do not apply to the position of the underwater buildings crossing each other.
Futbolda Sosyal Medya İletişimi ve Marka Değeri: Trabzonspor ve Taraftarları Üzerine Bir Çalışma
Authors: Demir Okan , Yıldız Salih 
Published: June 2020

Bulunduğumuz yüzyılda futbol kitleleri peşinden sürükleyen, farklı kültürlere sahip insanları bir araya getiren bir olgu olarak ortaya çıkmıştır. Futbolun bu birleştirici özelliği ekonomiden siyasete kadar farklı alanlarda söz sahibi insanların ilgisini çekmiştir. Futbol gün geçtikçe büyüyerek finansal açıdan ciddi bir pazar haline gelmiştir.	Bu pazarda yer alan ve kendini konumlandırmak isteyen futbol kulüpleri gelirlerini artırmak, kurumsallığını sürdürmek adına marka değerlerini korumak zorundadır. Bunun için sürekli gündemde kalmak ve değişim ve gelişim süreçlerine uyum sağlamak diğer sektörlerdeki şirketler için olduğu gibi futbol kulüpleri için de ön plana çıkmıştır.	Teknolojik gelişme ile paralel olarak-özellikle 21.yy’da- kitle iletişim araçlarında çok büyük değişimler meydana gelmiştir. Bu gelişmeler insanların iletişim ve erişim olarak kolayca ulaşabileceği ve kullanabileceği platformların oluşmasına yol açmıştır. Sosyal medya günümüzde bu platformların başında gelmektedir. Sosyal medya sayesinde çok kısa sürede çok sayıda insan ile iletişime geçmek ve onlardan geri bildirim almak ucuz ve kolay bir hale dönüşmüştür.	Bu çalışmada Türkiye Süper Liginde mücadele eden köklü takımlarımızdan olan Trabzonspor’un yoğun rekabet ortamında marka değerini korumak için sosyal medya iletişimi sayesinde oluşturduğu etkileşim ile bu renklere gönül veren taraftarların ortaya koyduğu etkileşimin kulübün marka değeri ve bileşenleri üzerinde etkisi araştırılmıştır. Çalışmada SPSS ve AMOS programları kullanılmış, elde edilen bilgiler yapısal eşitlik modeli ile değerlendirilmiş, taraftar merkezli sosyal medya iletişimi ve taraftar merkezli taraftar etkileşiminin takımın marka değerine olumlu etkisi olduğu saptanmıştır.
EVALUASI PROGRAM DESAIN PEMBELAJARAN PENDIDIKAN AGAMA ISLAM MELALUI MODEL CONTEXT, INPUT, PROCESS, PRODUCT (CIPP)
Authors: Amalina Nur 
Published: June 2020

This study aims to determine aspects of context, input, process and product Islamic Instructional Design in SMAN 4 Palopo. This study is a qualitative research. The approach was management. Analysis of the data used were descriptive analysis by performing data reduction, data presentation, and conclusion. The results of this study indicate that: (1) According to context, form of Islamic instructional design used was a curriculum-based learning design in 2013 formulated individually. The teachers' qualifications were accordance with the educational background and pedagogical competence of some teachers was still less than the maximum, and supporting factors were computer, papers, and printer. (2) According to input, the support of school and effort of the teachers was still less than the maximum. (3) According to process, the suitability of the utilization of the Islamic instructional design was sometimes appropriate and sometimes not appropriate. The time of making the Islamic instructional design conducted beginning of each semester, although sometimes the Islamic instructional design has not finished and the period of utilization of the Islamic instructional design was for one semester. (4) According to product, the impact of the utilization of the Islamic instructional design have positive impacts and negative impacts, and the students' responses to the utilization of the Islamic instructional design have positive response and negative response.