bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aberrant default mode network and auditory network underlying the sympathetic skin response of the penis (PSSR) of patients with premature ejaculation: A resting‐state fMRI study
Authors: Chen Jianhuai , Wu Wanke , Xiang Ziliang , Wang Qing , Huang Xinfei , Lu Chao , Liu Shaowei , Chen Yun , Yang Jie 
Published: September 2020

AbstractIntroductionHyperactivity of the sympathetic nervous system is considered as an important component involved in the pathological mechanisms of premature ejaculation (PE). However, the neural mechanisms of PE with high sympathetic activity are still not well understood.MethodsThe activity of the sympathetic innervations in the penis was evaluated by the sympathetic skin response of the penis (PSSR) with an electromyograph and evoked potential equipment. Resting‐state functional magnetic resonance imaging (fMRI) data were acquired from 18 PE patients with high sympathetic activity (sPE), 17 PE patients with normal sympathetic activity (nsPE), and 24 healthy controls (HC). We investigated the neural basis of sPE based on the measure of regional homogeneity (ReHo). Moreover, the correlations between brain regions with altered ReHo and PEDT scores and PSSR latencies in the patient group were explored.ResultsAltered ReHo values among three groups were found in the temporal, cingulated, and parietal cortex in the default mode network (DMN), as well as the temporal cortex in the auditory network (AUD). Compared with HC, Patients with sPE had increased ReHo values of brain regions in DMN, AUD, and decreased ReHo values of brain regions in DMN. In addition, increased ReHo values were found in DMN of patients with nsPE, while decreased ReHo values were found in DMN and the attention network (AN). Moreover, sPE patients had increased ReHo values in AUD and decreased ReHo values in DMN when compared with nsPE patients. Finally, altered ReHo values of brain regions in DMN and AUD were associated with PEDT scores and PSSR latencies in the patient group.ConclusionOur results suggested that PE patients had abnormal ReHo values in DMN, AUD, and AN. Patients with sPE were characterized by increased neuronal activity in AUD and decreased activity in DMN. This highlighted the significances of DMN, AUD, and AN in the pathophysiology of PE and also provided potential neuroimaging biomarkers for distinguishing sPE from nsPE and HC.
From epistemology to the method: phenomenology of the body, qì cultivation (qìgōng) and religious experiences in Chinese worlds
Authors: Micollier Evelyne 
Published: September 2020

AbstractAt the intersections of social anthropology, philosophy, and Asian studies, my paper explores the body ecologic through a phenomenological frame in the context of Chinese culture engaging both theory and method. How can qì cultivation experiences transporting bodies and persons in movement, within the world and their “life‐world,” be interpreted through a phenomenology of perception? Based on ethnographic study data collected mainly in South China (Guangzhou) and in Taiwan (1990s–2000s), this exploration is situated within qìgōng experiences (training, cultivating and mastering the qì). Anchored in martial, religious, and healing arts and their meanings, qìgōng’s myriad of forms and infinite variations invite journeys into religious Daoist and Buddhist practice, Chinese thought, and politico‐religious issues of past and present Chinese society. The qìgōng world, paths of knowledge transmission, healing horizons, claimed affiliations, and views of practitioners unveil an ontology and a cosmology grounded in religious (Daoist and Buddhist) lore.
The impact of structural optical coherence tomography changes on visual function in retinal vein occlusion
Authors: Michl Martin , Liu Xuhui , Kaider Alexandra , Sadeghipour Amir , Gerendas Bianca S. , Schmidt‐Erfurth Ursula 
Published: September 2020

AbstractPurposeWe aimed to determine the correlation between optical coherence tomography (OCT)‐ and demographic features and baseline best corrected visual acuity (BCVA) in treatment‐naïve patients with retinal vein occlusion (RVO).MethodsThis was a cross‐sectional posthoc analysis of OCT images that included RVO patients from two prospective, open‐label, multicentre studies. The morphological grading was done manually, in the standardized setting of a reading centre. Main outcome measure was the estimated difference in Early Treatment Diabetic Retinopathy Study letters associated with each individual biomarker.ResultsIncluded were 381/301 treatment‐naïve patients with BRVO/CRVO. For BRVO, statistically significant correlations with BCVA were seen for a 100 µm increase in central subfield thickness (CST; −3.1 letters), intraretinal cysts at centre point (CP; +4.1), subretinal fluid (SRF) at CP (+3.0) and hyperreflective foci (HRF) at the central B‐scan (−2.2). In CRVO, a 100 µm increase in CST was associated with a loss of −3.4 letters. In the total cohort, 100 µm increase in CST, SRF at CP and HRF at the central B‐scan correlated with a difference of −3.2,+3.2 and −2.0 letters. A 10‐year increase in age and female gender yielded a −2.0 and −2.5 letter decrease in the total cohort. Adjusted multiple R2 for the respective group was 18.3%/26.3%/23.5%.ConclusionsOf all parameters studied, only CST and age were consistently associated with worse BCVA in treatment‐naïve RVO patients. Morphology on OCT explained only a modest part of functional loss in this patient cohort.
Optical coherence tomography angiography of central serous chorioretinopathy patients’ response to breath‐holding manoeuvre
Authors: Karapapak Murat , Güven Dilek , Demir Mehmet , Tiryaki Demir Semra , Uslu Dogan Ceylan 
Published: September 2020

AbstractPurposeTo demonstrate through the use of optical coherence tomography angiography (OCTA) that normal vasoreactivity cannot be monitored in central serous chorioretinopathy (CSR) patients in the presence of vasoactive stimuli owing to hypoxia caused by the breath‐holding manoeuvre (BHM).MethodsThis cross‐sectional study included a total of 210 eyes, including 70 CSR patients (70 symptomatic eyes, 70 asymptomatic eyes) and 70 control group. Images of the macula (3 × 3 mm) and the optic disc (4.5 × 4.5 mm) were obtained at the baseline and after BHM using OCTA. The change in vascular parameters in the OCTA after BHM was evaluated in CSR patients and the control group.ResultsIn the symptomatic eyes of CSR patients, the mean whole image vessel density (VD) in the superficial capillary plexus decreased from 48.0 ± 3.5% under baseline conditions to 46.0 ± 4.5% after BHM (p < 0.01), and the mean whole VD in the deep capillary plexus decreased from 47.9 ± 8.0% under baseline conditions to 46.9 ± 6.7% after BHM (p < 0.01). The OCTA after BHM revealed a decrease in the mean whole image VD of the optic disc in both symptomatic (50.4 ± 2.1% to 49.6 ± 2.0%, p < 0.05) and asymptomatic (50.9 ± 1.8% to 50.4 ± 1.9%, p < 0.05) eyes of CSR patients. No difference for any mean VD of the control group was seen between the baseline and after BHM. Outer retinal flow areas increased significantly after BHM compared with the baseline in both eyes of CSR patients.ConclusionThese results suggest that CSR pathogenesis is related to an imbalance in local vascular regulation and the sympathetic activity of the autonomic nervous system. This technique constitutes a new way of studying retinal vascular changes and may be applied to CSR patients.
Association between age‐related macular degeneration and periodontal and peri‐implant diseases: a systematic review
Authors: Javed Fawad , Sculean Anton , Romanos Georgios E. 
Published: September 2020

AbstractThe aim of the present systematic review was to assess the association between age‐related macular degeneration (AMD) and periodontal and peri‐implant diseases. The focused question was ‘Is there a relationship between AMD and periodontal and peri‐implant diseases?’ Indexed databases were searched up to and including May 2020 to identify pertinent original studies. The Cochrane Collaboration’s tool was used to assess the risk of bias. Five observational cohort studies were included that assessed the association between AMD and periodontitis. The number of patients with and without AMD ranged between 54 and 90 and 1697 and 12,171 individuals, respectively. Examiner blinding to the study groups was performed in 1 of the 5 studies. None of the studies were power adjusted. Scrutiny of studies showed that all 5 studies included in the present systematic review had a high risk of bias. Results from all studies reported a direct association between AMD and periodontitis. No studies assessed the association between AMD and peri‐implant diseases. The association between AMD and periodontal and peri‐implant diseases remains debatable. Further well‐designed and power‐adjusted studies are needed to determine whether or not a ‘true’ association exists between AMD and periodontal and peri‐implant diseases.
Progression of macular atrophy in patients undergoing anti‐vascular endothelial growth factor therapy for neovascular age‐related macular degeneration
Authors: Cho Han Joo , Park Sang Min , Kim Jaemin , Nah Seung Kwan , Lee Jihyun , Lee Dong Won , Kim Jong Woo 
Published: September 2020

AbstractPurposeTo assess differences in the progression of macular atrophy (MA) between neovascular age‐related macular degeneration (AMD) subtypes and to identify the risk factors associated with the foveal involvement among patients with MA undergoing long‐term anti‐vascular endothelial growth factor (VEGF) treatment.MethodsEighty eyes of 80 patients with neovascular AMD who developed incident MA following anti‐VEGF therapy were retrospectively included. Macular atrophy (MA) was quantified using autofluoresence (AF) images within 24 months after the onset of MA, and the enlargement rate was compared between neovascular AMD subtypes. Regression models were constructed to explore relationships between foveal involvement in MA and baseline characteristics.ResultsThe growth rate of MA was 0.18 mm2/year for type 1 neovascularization (NV), 0.24 mm2/year for type 2 NV, and 1.21 mm2/year for type 3 NV; differences between groups were significant (p = 0.022). Multivariate logistic regression analysis revealed that thin subfoveal choroidal thickness (p = 0.028), presence of subretinal drusenoid deposit (p = 0.005), type 2 or 3 NV (p = 0.023), and geographic atrophy in the fellow eye (p = 0.035) were significant risk factors for MA with foveal involvement. The number of injections showed no significant association with the progression or the foveal involvement in MA.ConclusionsThe progression of MA in patients with neovascular AMD undergoing anti‐VEGF treatment differed significantly depending on the subtype of neovascularization. The risk of foveal involvement in MA was associated with the baseline factors or phenotype of neovascular AMD rather than with injection frequency of anti‐VEGF.
Detection of primary angleclosure suspect with different mechanisms of angle closure using multivariate prediction models
Authors: Zhang Ye , Dong Zhe , Zhang Qing , Li Lei , Thomas Ravi , Li Si Zhen , He Ming Guang , Wang Ning Li 
Published: September 2020

AbstractPurposeWe had found that a multivariate prediction model used for the detection of primary angle‐closure suspects (PACS) by combining multiple static and dynamic anterior segment optical coherence tomography (ASOCT) parameters had an area under the receiver operating characteristic curve (AUC) of 0.844. We undertook this study to evaluate this method in screening of PACS with different dominant mechanisms of angle closure (AC).MethodsThe right eyes of subjects aged ≥40 years who participated in the 5‐year follow‐up of the Handan Eye Study and had undergone gonioscopy and ASOCT examinations under light and dark conditions were included. All ASOCT images were analysed by the Zhongshan Angle Assessment Program. The dominant AC mechanism in each eye was determined to be pupillary block (PB), plateau iris configuration (PIC) or thick peripheral iris roll (TPIR). Backward logistic regression (LR) was used for inclusion of variables in the prediction models. LR, Naïve Bayes’ classification (NBC) and neural network (NN) were evaluated and compared using the AUC.ResultsData from 796 subjects (413 PACS and 383 normal eyes) were analysed. The AUCs of LR, NBC and NN in the PB group were 0.920, 0.918 and 0.917. The AUCs of LR, NBC and NN in the PIC group were 0.715, 0.708 and 0.707. The AUCs of LR, NBC and NN in TPIR group were 0.867, 0.833 and 0.886.ConclusionsPrediction models showed the best performance for detection of PACS with PB mechanism for AC and have potential for screening of PACS.
Intended responses to romantic partners’ annoying behaviours vary with willpower beliefs
Authors: Francis Zoë , Job Veronika 
Published: September 2020

When a romantic partner behaves in an annoying way – for example, by leaving a mess – we might respond with frustration or understanding. Responses may vary with contextual factors, including whether the partner could be mentally fatigued or depleted. We hypothesized that limited willpower theorists – who believe self‐control diminishes with use – might be especially likely to consider their partner’s preceding mental exertion. Two preregistered studies (combined N = 428) examined participants’ responses to four hypothetical scenarios. Limited theorists responded more compassionately to infractions performed after fatiguing days than to those performed after relaxing days; non‐limited theorists responded more consistently, regardless of context. Beliefs about one’s own willpower, rather than beliefs about one’s partner’s willpower, can affect how people respond to their partner’s undesirable behaviours.
Unworthy of Grief: Enduring Urban Violence in Northeast Brazil
Authors: Kolling Marie 
Published: September 2020

Pervasive urban violence has taken its toll on daily life in the northern part of Recife. Taking an ethnographic approach, and tracing recent developments of violent crime and homicide in Recife, this article explores the implications of the normalisation of violence. By thinking through how residents tried to protect themselves and endure the violence in practical and moral terms, the article seeks to elucidate why some members of the community – victims of violent crime and their mothers – were not deemed worthy of grief.
Quality of life in individuals with Down syndrome aged 4 to 21 years
Authors: Lee Anna , Knafl George , Knafl Kathleen , Van Riper Marcia 
Published: September 2020

AbstractBackgroundTo date, investigations of quality of life (QoL) in children with Down syndrome (DS) are rather limited. The purpose of this study was twofold: to examine QoL in children with DS and to explore possible differences in the QoL by age and gender.MethodsA cross‐sectional study of 211 parents of children with DS was conducted using an online survey that included a consent form, a demographic questionnaire and the English version of KidsLife, which is a measure of children's QoL.ResultsOur results demonstrated moderate or favourable levels of QoL except for the emotional well‐being domain among children with DS. The children's QoL showed no variance by gender. However, emotional and material well‐being, interpersonal relations and social inclusion varied by age.ConclusionsThe current findings provide important evidence that will help healthcare, educational and social services professionals to understand the multiple aspects of QoL in children with DS and support parents in their efforts to ensure the child's QoL. The results also point to the need to develop interventions aimed at improving QoL in those areas where children with DS are at increased risk for poorer QoL.
Autoantibodies associated with primary biliary cholangitis are common among patients with systemic lupus erythematosus even in the absence of elevated liver enzymes
Authors: Ahmad A , Heijke R , Eriksson P , Wirestam L , Kechagias S , Dahle C , Sjöwall C 
Published: September 2020

Summary
Knowledge of concomitant autoimmune liver diseases (AILD) is more detailed in primary Sjögren's syndrome (pSS) compared to systemic lupus erythematosus (SLE). Herein, the prevalence of autoantibodies associated with autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) was investigated in stored sera from patients with SLE (n = 280) and pSS (n = 114). Antibodies against mitochondria (AMA), liver–kidney microsomal (LKM) antigen, smooth muscle (SMA) and anti-nuclear antibodies (ANA) were analysed with immunofluorescence microscopy. In addition, AILD-associated autoantibodies were tested with immunoblot. Prior to sampling, eight SLE (2·9%) and three pSS (2·6%) cases were diagnosed with AILD. Among SLE-cases without known AILD (n = 272), 26 (9·6%) had PBC-associated autoantibodies, 15 (5·5%) AIH-associated autoantibodies (excluding ANA) and one serological overlap. Most subjects with PBC-associated autoantibodies had liver enzymes within reference limits (22 of 27, 81%) or mild laboratory cholestasis (two of 27, 7·4%), while one fulfilled the diagnostic PBC-criteria. AMA-M2 detected by immunoblot was the most common PBC-associated autoantibody in SLE (20 of 272, 7·4%). The prevalence of SMA (4·4%) was comparable with a healthy reference population, but associated with elevated liver enzymes in four of 12 (25%), none meeting AIH-criteria. The patient with combined AIH/PBC-serology had liver enzymes within reference limits. Among pSS cases without known AILD (n = 111), nine (8·1%) had PBC-associated, 12 (10·8%) AIH-associated autoantibodies and two overlapped. PBC-associated autoantibodies were found as frequently in SLE as in pSS but were, with few exceptions, not associated with laboratory signs of liver disease. Overall, AILD-associated autoantibodies were predominantly detected by immunoblot and no significant difference in liver enzymes was found between AILD autoantibody-negative and -positive patients.
Colour‐texture mapping associations in terms of preference
Authors: Fasllija Ela , Olguntürk Nilgün , Güvenç Dilek 
Published: September 2020

AbstractBasic design is the origin of many design‐related fields and covers different concepts such as pattern, colour, texture and relief. Because colour is rarely seen as a uniformly plain element, current research embraces colour and texture as equally important variables. Investigations consider the association of colour and texture in terms of preference. One hundred individuals trained in design, as well as 96 individuals not trained in design, participated in an experiment in a virtual and abstract environment. We chose four primary colours from Natural Colour System colour space (yellow, red, green and blue) with the same saturation and brightness values. They were associated with three different texture types (plain, basket and broken twill), which we obtained by scanning the physical textile samples. In the second part of the experiment, we attempted to find a relationship between colour and one texture variable, in this case texture strength. The results of the study do not verify the existence of a dependency between colour and texture in either sample group. Also, there is no verification that a relationship between colour and texture strength exists. Furthermore, the results show that overall blue is the most preferred colour. Moreover, all participants preferred fine textures to coarse ones. Design‐trained participants often associate fine strength level with basket texture whereas the non‐design–trained participants more often associate it with plain textures. Lastly, the majority of participants state that blue is their most preferred colour in fine rather than coarse textures.
Flying with the Dragon: Estimating Developing Countries’ Gains from China's Imports
Authors: Qian Xuefeng , Rafique Kalsoom , Wu Yingna 
Published: September 2020

AbstractAs a large trading nation, China competes with importing countries’ domestic and third‐country markets but also creates growth opportunities for exporters. Most studies on China trade shocks or “China shocks” focuse on the impacts of import competition on developed economies. The present paper complements research on China shocks by exploring the other side of the trade exposure to China – China as the largest importer, rather than as an exporter. We analyze the effects of export expansion into China on the local labor markets of the exporting developing countries for the years 1992 to 2018. Using detailed export and employment data, we estimate employment pattern variations in manufacturing industries with exports from other developing countries as instruments for export exposure. We find that the increase in trade exposure to China in the world economy has caused extensive job gains in manufacturing industries in developing countries that were exporters. On average, our estimations show that this trade exposure created approximately 1.5 million additional jobs from 1992 to 2018, which made an important contribution to manufacturing industries in developing countries. Our empirical analysis also shows that trade had stabilizing effects on employment in the countries in our sample generally.
The sticky mittens paradigm: A critical appraisal of current results and explanations
Authors: van den Berg Linda , Gredebäck Gustaf 
Published: September 2020

AbstractAlmost two decades ago, the sticky mittens paradigm was demonstrated as a way to train reaching and grasping behaviors in pre‐reaching infants, and consequently improve visual attentional abilities. In that first study, Needham and colleagues fitted 3‐month‐old infants with Velcro loop‐covered mittens and allowed them to interact with Velcro hook‐covered toys over the course of 2 weeks. In this review, we scrutinize the 17 studies that have followed those first sticky mittens results in regards to the motor, social perception, and visual attentional domains. Furthermore, we discuss the proposed mechanisms of the sticky mittens training. Current evidence strongly suggests that sticky mittens training facilitates social perception, which is consistent with prior correlational work showing links between action production and action perception. However, studies targeting motor and visual attentional abilities have too diverse results to warrant firm conclusions. We conclude that future research should focus on uncovering if there is a connection between sticky mittens training and motor behavior.