bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic tissue‐resident CD8+ T cells: A key player in obesity‐related diseases
Authors: Wang Lina , Sun Ping , Wu Yuzhang , Wang Li 
Published: September 2020

SummaryObesity‐induced low‐grade chronic inflammation in the metabolic tissues, such as adipose tissue (AT) and liver tissue, in individuals with obesity is a major etiological factor for several diseases, such as insulin resistance, type 2 diabetes, fatty liver disease, atherosclerosis and cardiovascular problems, as well as cancer and autoimmune diseases. Previous studies have revealed that tissue‐resident macrophages play a crucial role in this process. However, the mechanisms responsible for recruiting and activating macrophages and initiating chronic inflammation in the metabolic tissues have not yet been clearly elucidated. In the most recent decade, there has been a growing emphasis on the critical role of the adaptive CD8+ T cells in obesity‐induced chronic inflammation and related metabolic diseases. In this review, we will summarize the relevant studies in both mice and human regarding the role of metabolic tissue‐resident CD8+ T cells in obesity‐related inflammation and diseases, as well as the possible mechanisms underlying the regulation of CD8+ T cell recruitment, activation and function in the metabolic tissues, and discuss their potential as therapeutic targets for obesity‐related diseases.
Sella turcica morphology in patients with genetic syndromes: A systematic review
Authors: Roomaney Imaan A. , Chetty Manogari 
Published: September 2020

AbstractThe sella turcica is an important anatomical reference used in orthodontics for the evaluation of craniofacial growth. Studies have found variations in the sella turcica morphology in patients with syndromes affecting the craniofacial complex. This review aims to determine whether genetic syndromes involving the craniofacial complex are associated with abnormal radiographic sella turcica morphology and whether there is a pattern of malformation which is consistent within each syndrome. An electronic database search was conducted to identify relevant studies. We included primary studies describing the morphology of the sella turcica on lateral radiographs in human subjects with genetic syndromes involving the craniofacial complex. No restrictions were placed on language or timeframe. PROSPERO registration CRD42019148060. Thirty‐eight studies were included in this review. A ‘J’‐shaped sella was found in patients with Hutchinson‐Gilford‐Progeria syndrome and other syndromes. A bulbous dorsum sellae was highly prevalent Cleidocranial dysplasia, and a bulbous dorsum sellae and uneven contours of the clivus was found in Cri du chat syndrome. A steep clivus was described in patients with Axenfeld‐Rieger syndrome. An oblique anterior wall was the most frequent malformation found in Down’s syndrome. Genetic syndromes affecting the craniofacial complex are associated with abnormal morphology of the radiographic sella turcica. Clinicians should be observant of abnormal sella turcica morphology which can be a sign of undiagnosed or subclinical syndromes. More high‐quality studies are needed which use standardized and objective methods of determining the morphology of the sella turcica.
CO2emissions, urban population, energy consumption and economic growth in selected African countries: A Panel Smooth Transition Regression (PSTR)
Authors: Mosikari Teboho Jeremiah , Eita Joel Hinaunye 
Published: September 2020

AbstractThis study investigates the non‐linear impact of urban population, energy consumption and economic growth on carbon emissions in selected African economies, for the period 2005–2019. The investigation is conducted through the application of non‐linear panel smooth transition regression (PSTR) estimation technique. The results reveal a rejection of the null hypothesis of linearity, in favour of non‐linearity. The results provide evidence of the presence of environmental Kuznets curve (EKC). Energy consumption has a positive impact on carbon emissions in both regimes. An increase in urban population causes a reduction in carbon emissions. The study recommends that in an effort to accelerate economic growth, policymakers should implement policies aimed at achieving low carbon mechanisms, such as green infrastructure and renewable energy systems, which reduce energy consumption and greenhouse gas emissions. It is therefore important for the selected African economies to come up with programmes that increase awareness about the risk of carbon emissions.
Does any relationship between energy consumption and economic growth exist in India? A var model analysis
Authors: Singh Kamaljit , Vashishtha Simmi 
Published: September 2020

AbstractEnergy is the lifeblood of the global economy, a key input to almost all the goods and services of the modern world. The primary objective of this study is to examine the relationships between per capita energy consumption and per capita GDP in India from 1970–1971 to 2014–2015. The data analysis was conducted using the three‐stage Johnson cointegration, vector autoregression and Granger causality test. The results of the study documented that there was the presence of unidirectional causality running from per capita GDP to per capita energy consumption and the absence of a long‐term equilibrium relationship between per capita energy consumption and per capita GDP in India. More significantly, India has already demonstrated an impressive ability to develop, deploy, replicate and scale up innovative, market‐based approaches to energy efficiency. The country has an excellent basis for further energy efficiency policy innovation and market creation, including a strong community of non‐governmental organisations, research institutes and think tanks active in energy efficiency.
Psychometric properties of the Chinese version thriving of older people assessment scale
Authors: Li Chih‐Ping , Lee Shu‐Fen , Bergland Ådel , Edvardsson David 
Published: September 2020

AbstractBackgroundThe Thriving of Older People Assessment Scale has Scandinavian, Norwegian and English versions but does not yet have a Chinese version that can be used in Chinese populations and compared to global data.ObjectivesTo evaluate the psychometric properties of the translated Chinese version of the Thriving of Older People Assessment Scale.MethodsThe English version of the Thriving of Older People Assessment Scale was translated into Chinese using a forward and backward translation method. A convenience sampling strategy was used to recruit participants from five long‐term care facilities in northern Taiwan (N = 285). Confirmatory factor analysis was then performed to confirm the theory of the Thriving of Older People Assessment Scale Chinese version.ResultsThe Thriving of Older People Assessment Scale Chinese version consists of 32 items loading across five domains, namely, ‘resident attitudes towards being in long‐term care’, ‘quality of care and caregivers’, ‘resident engagement and peer relationships’, ‘keeping in touch with people and places’ and ‘quality of the physical environment’, with good internal consistency (0.971). Confirmatory factor analysis results showed that χ2 = 2255.58 (df = 459, p < .00), χ2/df = 4.91, CFI = 0.96, IFI = 0.96, NNFI = 0.96 and SRMR = 0.074, indicating a good model fit to previous factor structures.ConclusionsThe Thriving of Older People Assessment Scale Chinese version is a tentatively reliable and valid tool for measuring the experience of thriving in Chinese language older people in long‐term care facilities.Implications for practiceThe Chinese version of Thriving of Older people Assessment scale can be used to describe the levels of place‐related well‐being among older Chinese people living in long‐term care. Further research and improvements of the Thriving of Older People Assessment Scale Chinese version in diversified Chinese contexts will enable a more comprehensive understanding of older Chinese people’s experiences of thriving in long‐term care.
Palliative and end‐of‐life educational interventions for staff working in long‐term care facilities: An integrative review of the literature
Authors: Iida Kieko , Ryan Assumpta , Hasson Felicity , Payne Sheila , McIlfatrick Sonja 
Published: September 2020

AbstractBackgroundGiven the increase in the number of deaths within long‐term care facilities (LTCFs), the need for palliative and end‐of‐life (EOL) care education among such facilities has been increasing. As such, a systematic synthesis of global palliative and EOL care educational approaches and evaluation can aid further educational development.ObjectiveTo synthesise the current literature on palliative and EOL care educational interventions for staff working in LTCFs and identify barriers to, and facilitators of, intervention implementation.MethodsThe study used an integrative review framework wherein indexed databases, namely, CINAHL, EMBASE, MEDLINE, PsycINFO, Web of Science, Cochrane Library and Japan Medical Abstract Society, were systematically searched for studies published in English and Japanese between 2007 and 2019. Search terms that are related to palliative care, LTCF, and education were combined to increase search sensitivity. The quality of the papers was assessed using Joanna Briggs Institute Critical Appraisal Tools and the Mixed‐Methods Appraisal Tool.ResultsA total of 52 studies were included in the review. Our results suggested that although studies in this area and setting have been evolving, suboptimal developmental research and educational practices, global variability and unstandardised approaches to education and lacking viewpoints from service users have remained. Barriers to intervention implementation were also reported due to the specific characteristics of LTCFs, which include high staff turnover and considerable variation in professional skills and experience.ConclusionsGiven the different LTCF types, systems and policies across each country or region, further research on standardised educational interventions with contextual considerations using large‐scale studies with robust methodology is needed to meet the increasing demand for palliative and EOL care among the global ageing population.Implications for practicePalliative and EOL care educational intervention for LTCF staff need to include more consideration of context, organisational culture and the user involvement throughout the process of education and research to enhance the quality of care in this complex setting.
Developing a competence framework for cognitive analytic therapy
Authors: Parry Glenys , Bennett Dawn , Roth Anthony D. , Kellett Stephen 
Published: September 2020

ObjectiveThis paper describes the development and summarizes the content of a competence framework for delivery of cognitive analytic therapy (CAT).DesignThe framework was developed using the evidence‐based method developed by Roth and Pilling (2008, Behavioural and Cognitive Psychotherapy, 36, 129).MethodsA review of the CAT outcome literature identified where CAT interventions had evidence of efficacy. Standard texts on CAT were primary sources for details of theory and practice. This process was supported by an expert reference group (ERG). The role of the ERG was to provide professional advice on areas where the evidence base was lacking, but where CAT interventions were commonly used by therapists trained in the model.ResultsA framework was produced and structured in terms of core knowledge, core skills, and meta‐competences (which require therapeutic judgement rather than simple adherence to a treatment protocol).ConclusionsThe framework enables trainees, service users, service managers, and commissioners to better understand a) the core features of CAT and b) what competences need to be in place for CAT to be skilfully delivered in practice.Practitioner points

It is possible to define the core competences of CAT.

Whilst generic competences are important, there are five CAT‐specific domains of competence.

The CAT‐specific competences reflect the three‐phase structure of the therapy: reformulation, recognition, and revision.
COVID‐19 distress and worries: The role of attitudes, social support, and positive coping during social isolation
Authors: Moore Kathleen A. , Lucas James J. 
Published: September 2020

As the COVID‐19 pandemic accelerates, one public health response has been for governments to impose quarantine ‘lockdowns’ which require people to socially isolate. In this study, we explored the level of psychological distress that people experienced in social isolation and the factors which might ameliorate or exacerbate it. Two hundred and thirteen participants (69% female) with a mean age of 37.82 years participated in an online study. They completed a series of questions designed as part of a larger cross‐national study. A positive attitude towards social isolation introduced by government as a strategy to reduce the transmission of COVID‐19 was predictive of positive coping strategies, and both attitude and coping predicted reduced psychological distress. Participants’ worries about contagion of COVID‐19, their financial status, and the economic and political impact of the COVID‐19 pandemic predicted increases in their psychological distress. Social support from family and work colleagues was not significant in reducing worries or psychological distress but it did positively predict engagement in coping. The findings and recommendations are discussed.Practitioner points

Fostering a positive attitude towards social isolation in clients: reduces psychological distress, fosters engagement in positive coping behaviours.

Enhancing clients’ level of social support received will serve to increase positive coping and indirectly reduce psychological distress during social isolation.

Strategies to reduce clients’ COVID‐19 worries are important as worry contributes to their overall level of psychological distress.
A rapid real‐time PCR assay for detecting columnar growth in apples (Malus × domestica)
Authors: Cmejlova Jana , Vavra Radek , Cmejla Radek 
Published: September 2020

AbstractColumnar growth in apples can have considerable positive consequences for orchard maintenance, but the lack of columnar cultivars producing fruits with desired market quality prevents their broader utilization in orchards. New crossings focused on their breeding are therefore conducted throughout the world every year. Unfortunately, the reliable discrimination between columnar growth and normal phenotype is difficult until seedlings are 2–3 years of age. However, molecular marker–assisted selection (MAS) can be used in seedlings several weeks old providing immense help in breeding programmes focused on columnar apple production. Here, we describe a rapid and reliable method for the detection of both wild‐type (WT) and columnar (Co) alleles originating from ‘McIntosh Wijcik’ in a single reaction using a real‐time PCR allelic discrimination approach. Our assay was tested in 130 genotypes (80 normal and 50 columnar habit) from various crossings and their parents, and in all cases, genotype corresponded to phenotype. The assay is thus suitable for laboratories interested in high‐throughput MAS for columnar tree habit breeding.
Across climates and species, higher vapour pressure deficit is associated with wider vessels for plants of the same height
Authors: Olson Mark E. , Anfodillo Tommaso , Rosell Julieta A. , Martínez‐Méndez Norberto 
Published: September 2020

AbstractWhile plant height is the main driver of variation in mean vessel diameter at the stem base (VD) across angiosperms, climate, specifically temperature, does play an explanatory role, with vessels being wider with warmer temperature for plants of the same height. Using a comparative approach sampling 537 species of angiosperms across 19 communities, we rejected selection favouring freezing‐induced embolism resistance as being able to account for wider vessels for a given height in warmer climates. Instead, we give reason to suspect that higher vapour pressure deficit (VPD) accounts for the positive scaling of height‐standardized VD (and potential xylem conductance) with temperature. Selection likely favours conductive systems that are able to meet the higher transpirational demand of warmer climates, which have higher VPD, resulting in wider vessels for a given height. At the same time, wider vessels are likely more vulnerable to dysfunction. With future climates likely to experience ever greater extremes of VPD, future forests could be increasingly vulnerable.
Metabolic flux from the chloroplast provides signals controlling photosynthetic acclimation to cold in Arabidopsis thaliana
Authors: Herrmann Helena A. , Dyson Beth C. , Miller Matthew A. E. , Schwartz Jean‐Marc , Johnson Giles N. 
Published: September 2020

AbstractPhotosynthesis is especially sensitive to environmental conditions, and the composition of the photosynthetic apparatus can be modulated in response to environmental change, a process termed photosynthetic acclimation. Previously, we identified a role for a cytosolic fumarase, FUM2 in acclimation to low temperature in Arabidopsis thaliana. Mutant lines lacking FUM2 were unable to acclimate their photosynthetic apparatus to cold. Here, using gas exchange measurements and metabolite assays of acclimating and non‐acclimating plants, we show that acclimation to low temperature results in a change in the distribution of photosynthetically fixed carbon to different storage pools during the day. Proteomic analysis of wild‐type Col‐0 Arabidopsis and of a fum2 mutant, which was unable to acclimate to cold, indicates that extensive changes occurring in response to cold are affected in the mutant. Metabolic and proteomic data were used to parameterize metabolic models. Using an approach called flux sampling, we show how the relative export of triose phosphate and 3‐phosphoglycerate provides a signal of the chloroplast redox state that could underlie photosynthetic acclimation to cold.
Efficient removal of black henna tattoos
Authors: Ferrari David M. , Hoffmann Johanna C. , Schön Michael P. , Lippert Undine 
Published: September 2020

AbstractBackground/ObjectivesPara‐phenylenediamine, a dye frequently added to henna tattoos to create the black color, is a potent contact allergen. Severe contact dermatitis may arise within days even after the first application. Our objective was to develop a method for rapid and complete removal of para‐phenylenediamine‐containing black henna tattoos from the skin, an important problem many physicians are confronted with, but for which no simple method exists.MethodsA database search revealed polyethylene glycol 400, described in removal of ortho‐phenylenediamine from contaminated skin. We therefore investigated its use in removal of the structurally related ortholog para‐phenylenediamine present in black henna tattoos.ResultsA protocol was established involving repeated cycles of rinsing of the skin with polyethylene glycol 400 solution. In 5 patients, one of whom had already developed a severe blistering contact dermatitis and another a mild erosive dermatitis, black henna tattoos were successfully removed. Removal was completed in a single session of 1 hour or less, depending on tattoo size, with a maximum of 6 rinse cycles.ConclusionsWe provide a simple and safe method for rapid and effective removal of black henna tattoos. This procedure requires no special equipment and can be applied in virtually any setting.
Radiofrequency ablation‐induced thermal cutaneous injury in a neonate: A potential complication after intrauterine radiofrequency ablation
Authors: Law Je Yin , Choi Ellie CE , Chandran Nisha Suyien 
Published: September 2020

AbstractOver the years, the application and complications of radiofrequency ablation (RFA) in selective fetal reduction for complex pregnancies have been increasingly documented. Despite its rising use in the field of obstetrics and gynecology, the cutaneous complications of RFA have not been commonly reported. Here, we present a case of cutaneous thermal injury to the fetus likely secondary to intrauterine RFA for fetal reduction.
Topical cidofovir for the treatment of recalcitrant viral warts and molluscum contagiosum in Jacobsen syndrome
Authors: Alsaleemi Ali , O’Connor Cathal , Irvine Alan D. , Leahy Timothy Ronan 
Published: September 2020

AbstractJacobsen syndrome is caused by a terminal deletion on the long arm of chromosome 11 and can be associated with immunodeficiency. Patients with Jacobsen syndrome can be predisposed to cutaneous viral infections that are difficult to treat. We report successful use of topical 1% cidofovir as treatment of recalcitrant verruca vulgaris in one patient and molluscum contagiosum in another patient with Jacobsen syndrome. Topical cidofovir appears to be a good treatment option in this cohort and should be considered early for treatment‐resistant cutaneous viral infections.
Social support, strain, and glycemic control: A path analysis
Authors: Maki Kristin G. 
Published: September 2020

AbstractSocial support and strain have been linked with many health outcomes. However, less is known about whether these psychosocial factors are associated with Type 2 diabetes risk. This study uses the Midlife in the United States (MIDUS) dataset to examine the relationship between social support and strain from friends, family members, and spouse/partners and blood hemoglobin A1c levels in married/cohabiting adults who have not been diagnosed with diabetes. In addition, health locus of control is examined as a possible mediator. The study's findings suggest that support from friends is negatively associated with HbA1c levels, indicating a relationship between better glycemic control and social support from friends, and an indirect association for spouse/partner support. A direct effect for internal health locus of control was also found.
Multisensory evidence
Authors: O'Callaghan Casey 
Published: September 2020

AbstractIt is tempting to think that one's perceptual evidence comprises just what issues from perceiving with each of the respective sensory modalities. However, empirical, rational, and phenomenological considerations show that one's perceptual evidence can outstrip what one possesses due to perceiving with each separate sense. Some novel perceptual evidence stems from the coordinated use of multiple senses. This paper argues that some perceptual evidence in this respect is distinctively multisensory.
Association of Community Health Nursing Educators 2020 Research Priorities and Research in Action Model
Authors: McElroy Katie G. , Stalter Ann M. , Smith Stephanie D. 
Published: September 2020

AbstractObjectiveThe Association of Community/Public Health Nurse Educators (ACHNE) Research Priorities Subcommittee presents a report on the state of the science of public health nursing education.DesignWhittemore and Knafl's (Journal of Advanced Nursing, 2005, 52, 546) five‐step integrative review was used. Sample: Fifty‐two articles were reviewed.MeasurementsBraun et al's. (Handbook of research methods in health social sciences, 2019, 843) thematic analysis methods were used.ResultsFour themes emerged: (a) Community/Public Health Nursing Education and teaching strategies/modalities; (b) Clinical teaching and learning partnerships; (c) Environmental health and emergency response; and, (d) Cultural competence and awareness.ConclusionsThemes informed the following research priorities: (a) a need for rigorous scientific studies highlighting the impact and effectiveness of Community/Public Health Nursing Education; (b) a need for evidence on faculty development, support and training related to community/public health activities; (c) a need for evidence on impact of Community/Public Health Nursing teaching on communities and students, and (d) a need for evidence on impact of C/PHNE strategies on long‐term student knowledge, attitudes or behavior (competencies). Finally, a Research in Action Model is proposed as a means for continued forward movement of the discipline, connecting the three fundamental driving mechanisms.