bluuebunny/crossref_metadata_2025_split huggingface dataset:
Choosing best practices for managing impacts of trawl fishing on seabed habitats and biota
Authors: McConnaughey Robert A. , Hiddink Jan G. , Jennings Simon , Pitcher C. Roland , Kaiser Michel J. , Suuronen Petri , Sciberras Marija , Rijnsdorp Adriaan D. , Collie Jeremy S. , Mazor Tessa , Amoroso Ricardo O , Parma Ana M. , Hilborn Ray 
Published: December 2019

AbstractBottom trawling accounts for almost one quarter of global fish landings but may also have significant and unwanted impacts on seabed habitats and biota. Management measures and voluntary industry actions can reduce these impacts, helping to meet sustainability objectives for fisheries, conservation and environmental management. These include changes in gear design and operation of trawls, spatial controls, impact quotas and effort controls. We review nine different measures and actions and use published studies and a simple conceptual model to evaluate and compare their performance. The risks and benefits of these management measures depend on the extent to which the fishery is already achieving management objectives for target stocks and the characteristics of the management system that is already in place. We offer guidance on identifying best practices for trawl‐fisheries management and show that best practices and their likelihood of reducing trawling impacts depend on local, national and regional management objectives and priorities, societal values and resources for implementation. There is no universal best practice, and multiple management measures and industry actions are required to meet sustainability objectives and improve trade‐offs between food production and environmental protection.
Diphthamide modification of eEF2 is required for gut tumor‐like hyperplasia induced by oncogenic Ras
Authors: Tsuda‐Sakurai Kayoko , Kimura Masaki , Miura Masayuki 
Published: December 2019

AbstractEukaryotic elongation factor 2 (eEF2) undergoes a unique post‐translational modification called diphthamidation. Although eEF2 diphthamidation is highly conserved, its pathophysiological function is still largely unknown. To elucidate the function of diphthamidation in tumor, we examined the involvement of diphthamidation pathway enzyme Dph5 in tumor progression in Drosophila adult gut. Expression of oncogenic RasV12 in gut intestinal stem cells (ISCs) and enteroblasts (EBs) causes hypertrophy and disruption of gut epithelia, and shortened life span. Knockdown of Dph5 ameliorated these pathogenic phenotypes. Dph5 is required for gross translation activation and high dMyc protein level in RasV12 tumor‐like hyperplasia. Transcriptome analysis revealed that Dph5 is involved in the regulation of ribosome biogenesis genes. These results suggest that diphthamidation is required for translation activation partly through the regulation of ribosome biogenesis in Ras‐induced tumor‐like hyperplasia model in Drosophila gut.
Expediting learning through peer teaching: experiences with the Jigsaw technique
Authors: Woods Helen Buckley 
Published: December 2019

AbstractWhen designing a teaching session, lack of time and the weight of custom and practice can lead to methods being repeated routinely (Woods, 2013a). The institutional context and student demographic are also fundamental in determining teaching design (Fry, Ketteridge & Marshall, 2015). In this feature, a versatile teaching method (Jigsaw) is described with reference to theories of learning. Examples of its application in professional learning contexts are presented and discussed.
D.I.
The criterion‐related validity of a short commensurate measure of personality‐based person‐organization fit
Authors: Iyer Punya V. , Oostrom Janneke K. , Serlie Alec W. , van Dam Arjan , Born Marise Ph. 
Published: December 2019

AbstractOur goal was to develop a commensurate measure of personality‐based person‐organization fit and examine its criterion‐related validity for two retention‐related attitudes: job satisfaction and intention to stay. At T0, 637 employees completed our questionnaire. Two years later, at T1, 171 of the original respondents completed our questionnaire again. Results showed that the organizational personality perceptions are relatively stable. Polynomial regression analyses and surface plots revealed that job satisfaction and intention to stay are higher when there is perfect fit between the person and the organization compared to when the person and the organization differ in traits. However, in most cases, we found the work attitudes to be maximized when both the person and the organization score high on the personality traits.
Long‐term outcomes of pediatric kidney transplantation: A single‐center experience over the past 34 years in Japan
Authors: Aoki Yujiro , Hamasaki Yuko , Satoh Hiroyuki , Matsui Zenichi , Muramatsu Masaki , Hamada Riku , Harada Ryoko , Ishikura Kenji , Hataya Hiroshi , Honda Masataka , Sakai Ken , Shishido Seiichiro 
Published: December 2019

ObjectivesTo evaluate long‐term outcomes and risk factors for graft loss in pediatric kidney transplantation over a 30‐year period.MethodsWe retrospectively assessed 400 consecutive kidney transplants carried out in 377 children during 1975–2009. Patients were stratified according to the immunosuppressive regimen (era 1: methylprednisolone and azathioprine; era 2: calcineurin inhibitor‐based therapy, including methylprednisolone and azathioprine or mizoribine; era 3: basiliximab induction therapy, including calcineurin inhibitors, methylprednisolone and mycophenolate mofetil).ResultsThe median age and bodyweight at transplantation were 9.7 years and 20.6 kg, respectively. In total, 364 (91.0%) children received a living related donor transplantation. The acute rejection rate within 1 year post‐transplant decreased significantly from 61.0% in era 1 to 14.5% in era 3 (P < 0.001). For transplant eras 1–3, 1‐year graft survival was 81%, 93% and 95%; 5‐year graft survival was 66%, 86% and 93%; and 10‐year graft survival was 47%, 79% and 89%, respectively. The overall 5‐, 10‐ and 20‐year patient survival rates were 96%, 93% and 88%, respectively. A Cox multivariate analysis identified cold ischemia time (hazard ratio 1.385, 95% confidence interval 1.251–1.603), acute rejection (hazard ratio 1.682, 95% confidence interval 1.547–3.842), re‐transplant (hazard ratio 2.680, 95% confidence interval 1.759–3.982) and donor type (hazard ratio 2.957, 95% confidence interval 1.754–4.691) as independent risk factors for graft loss at 10 years post‐transplant.ConclusionsThe progress of immunosuppressive therapy has led to a low incidence of acute rejection and a high graft survival rate across 30 years of pediatric transplantation.
Gas‐solid displacement reactions in the Ti–W–C system
Authors: Dempsey Ryan D. , Lipke David W. 
Published: December 2019

AbstractDisplacement reactions between binary and ternary ceramics in the Ti–W–C system and reactive gaseous atmospheres are investigated in this work. Specifically, WC and 50:50 wt% TiC:WC solid solution powders were exposed to flowing hydrogen gas, or equilibrated against an excess of titanium in the presence of iodine, to form metallic tungsten and TiC solid products. In the case of pure WC reacting with hydrogen, transformation to metallic tungsten occurred as a result of removal of chemically bound carbon as gaseous hydrocarbons. In the case of pure WC reacting with titanium iodide vapors, transformation was accompanied by the appearance of TiC as a solid product formed at the gas‐solid interface. In the case of 50:50 wt% TiC:WC solid solution powders, hydrogen was generally found to be an ineffective displacing reagent, whereas reaction with titanium iodide vapors was observed to proceed virtually to completion, resulting in a two phase product mixture comprising metallic tungsten and TiC. For the latter case, a variety of microstructures could be observed within a given batch, including tungsten platelets and/or lamellae in a TiC matrix, or coarse tungsten grains interspersed with TiC grains. These morphological variations are speculated to arise from compositional variation in the starting material and the occurrence of local rapid coarsening along fast diffusion pathways within reacting agglomerates and polycrystalline primary particles. The observed reaction products and relative efficacy of gaseous reagents to promote displacement reactions in the Ti–W–C system are rationalized on the basis of thermodynamic predictions. The reaction between 50:50 wt% TiC:WC solid solution powders and titanium iodide vapors constitutes the first known report of an internal displacement reaction proceeding via gaseous intermediates in a nonoxide ceramic system.
The effects of social messaging on students' learning and intrinsic motivation in peer assessment
Authors: Li Lan , Gao Fei , Guo Shuqing 
Published: December 2019

AbstractThis study aims to gain a better understanding of how the newly arisen social messaging may impact the practice of peer assessment. Seventy‐nine ESL (English as second language) students reviewed each other's English essays in three peer assessment groups: a three‐member group using wiki (wiki group), a three‐member group using social messaging (small messaging group), and a six‐member group using social messaging (big messaging group). Data analysis suggested that peer assessment facilitated by social messaging can be at least of the same effectiveness as wiki‐facilitated peer assessment on ESL students' writing skills and intrinsic motivation. In addition, the findings indicated that students in the small messaging group outperformed students in the big messaging group on essay writing and reported a significantly higher rating on perceived competence, a positive indicator of the behavioural measures of intrinsic motivation, than students in the big messaging group.
Forging ahead: Update on radiofrequency ablation technology and techniques
Authors: Sandhu Amneet , Nguyen Duy T. 
Published: December 2019

AbstractInnovations in radiofrequency (RF) ablation and nonablative techniques have led to significant advances in addressing complex arrhythmogenic substrates for a variety of cardiac arrhythmias. Anatomical challenges, deep substrate, and mid‐myocardial locations may pose difficulties and decrease success rates using routine methods. In this review, we provide an update on novel RF technology and techniques including (a) high‐power, low‐duration ablation, (b) ablation facilitated by low‐ionic irrigant, and (c) bipolar ablation. In addition, we review emerging technologies including electroporation, needle catheter ablation, and ablation with the lattice catheter.
Association between the Geriatric Nutritional Risk Index, bone mineral density and osteoporosis in type 2 diabetes patients
Authors: Wang Liang , Zhang Die , Xu Jing 
Published: December 2019

AbstractAims/IntroductionLow bodyweight and hypoalbuminemia are independently associated with osteoporosis. In this study, the relationship among the Geriatric Nutritional Risk Index (GNRI), bone mineral density (BMD) and osteoporosis in type 2 diabetes mellitus patients was explored, and the GNRI predictive value was evaluated.Materials and MethodsWe enrolled 225 men and 192 women with type 2 diabetes mellitus. Their general condition, and laboratory and BMD data were collected. Spearman’s partial correlation analysis adjusting for age, body mass index and albumin was used for exploring the association among the GNRI, BMD and bone metabolism markers. Statistical analyses, including multivariate regression analysis and receiver operating characteristic curve analysis, were also applied in this study.ResultsOn Spearman’s partial correlation analysis, GNRI was positively associated with BMD and albumin‐corrected calcium (r = 0.145–0.561, P < 0.01). For the multivariate regression analysis, we observed that the GNRI was dramatically related to high total lumbar, total hip, femur neck BMD and osteoporosis (odds ratio 0.857 for men and 0.927 for women, all P < 0.05). The area under the receiver operating characteristic curve of the GNRI (0.876 for men and 0.704 for women, all P < 0.01) was the largest compared with that of albumin and body mass index in osteoporosis prediction.ConclusionsIn this study, it was shown that the GNRI was positively correlated with BMD, and inversely correlated with osteoporosis in type 2 diabetes mellitus patients. In addition, compared with body mass index, albumin and age, the GNRI was a more powerful indicator for osteoporosis.
Characterization of a novel Yersinia ruckeri serotype O1‐specific bacteriophage with virulence‐neutralizing activity
Authors: Welch Timothy J. 
Published: December 2019

AbstractA lytic bacteriophage (φNC10) specific to serotype O1 Yersinia ruckeri has been identified and evaluated as a model to assess the potential use of bacteriophages and their products for disease control in aquaculture. Electron microscopy of purified φNC10 revealed a virion particle with a small (70 nm) polyhedral head and short tail. φNC10 infected only serotype O1 strains of Y. ruckeri and failed to bind a defined Y. ruckeri mutant strain lacking O1 lipopolysaccharides (O1‐LPS), suggesting that φNC10 uses O1‐LPS as its receptor. In addition, spontaneous φNC10‐resistant mutants of Y. ruckeri exhibited defects in O1‐LPS production and were sensitive to rainbow trout serum. Purified φNC10 displayed a polysaccharide depolymerase activity capable of degrading Y. ruckeri O1‐LPS and thereby sensitizing Y. ruckeri to the bactericidal effects of rainbow trout serum. The φNC10‐associated polysaccharide depolymerase activity also reduced the ability of Y. ruckeri cells to cause mortality following intraperitoneal injection into rainbow trout. These data demonstrate a potential utility of φNC10 and its associated polysaccharide depolymerase activity for Y. ruckeri disease prevention.
When family dining protects against sweet food consumption… and when it does not
Authors: Laporte Marie‐Eve , Rieunier Sophie , Michel Geraldine 
Published: December 2019

AbstractThe World Health Organization recommends reducing sugar intake in order to improve one's health. In this spirit, the aim of this research is to test the impact that dining as a family has on the consumption of sweet food and to compare the results with the impact of dining alone or with friends, at home or away. Based on a mixed‐method design combining an experiment with a descriptive survey, the results show that family dining at home fosters healthier eating behavior by restricting sweet food consumption, while dining alone or with friends at home leads more consumption of sweet foods. However, this protective effect of family dining does not hold outside the home. This study helps explain the contradictions in the literature regarding how the presence of others influences food intake. It provides guidance to policy and business stakeholders on ways to reduce sugar consumption and to improve consumers' eating behaviors.
Improvement of skin texture and wrinkles using radiofrequency ultra‐thin electrode technology
Authors: Gold Michael H. , Biron Julie , Wilson April 
Published: December 2019

AbstractBackgroundApplication of radiofrequency (RF) energy with microneedles to facial skin shown to promote skin renewal.AimTo evaluate the safety and efficacy of the VoluDerm technology with 100 ultra‐thin electrodes gen100 tip for improvement of skin texture and wrinkles.MethodsA prospective, open‐label, intra‐individual‐controlled trial. Twelve subjects (mean age, 45.5; Fitzpatrick skin types II‐III) with Fitzpatrick Elastosis Scale (FES) score 3‐6 were treated with VoluDerm RF technology using the gen100 ultra‐thin electrodes disposable tip. The participants underwent three treatments at 3‐week intervals. Treatment safety was evaluated at each treatment visit and at the follow‐up visits (1 and 3 months post last treatment). Efficacy of treatment evaluated at 1 and 3 months after the last treatment using the FES as well as evaluator‐ and subject‐rated Global Aesthetic Improvement Scale (GAIS).ResultsTreatment was well tolerated, with no downtime or adverse events. One and three months after the last treatment session, physician‐rated FES showed statistically significant improvement of 2.67 ± 1.18 and 2.33 ± 1.03, respectively (P < .0001), from baseline (4.83 ± 0.69). According to the investigator assessment of improvement using the GAIS scale, all subjects had an improvement in skin texture and pigmentation and most of the patients (91.7%) had an improvement in skin brightness, tightness, and wrinkles.ConclusionThis is the first study evaluating the Legend+ RF System with VoluDerm technology using the novel gen100 ultra‐thin electrodes tip. This study demonstrated effective and well‐tolerated treatment for improving skin texture and appearance with minimal to no downtime.
Retracted: Risk Management in Financial Institutions
Authors: RAMPINI ADRIANO A. , VISWANATHAN S. , VUILLEMEY GUILLAUME 
Published: December 2019

ABSTRACTWe study risk management in financial institutions using data on hedging of interest rate and foreign exchange risk. We find strong evidence that institutions with higher net worth hedge more, controlling for risk exposures, across institutions and within institutions over time. For identification, we exploit net worth shocks resulting from loan losses due to declines in house prices. Institutions that sustain such shocks reduce hedging significantly relative to otherwise‐similar institutions. The reduction in hedging is differentially larger among institutions with high real estate exposure. The evidence is consistent with the theory that financial constraints impede both financing and hedging.
“H Newman” and Ludwig Wittgenstein: Re-evaluating the History of John Henry Newman's Philosophical Reception
Authors: Morris-Chapman Daniel Pratt 
Published: December 2019

AbstractIt is commonly held that that the dominance of logical positivism, in the early part of the twentieth-century, hindered Newman's philosophical recognition. However, commentators also argue that Newman's writing began to gain wider recognition following Wittgenstein's reference to “H Newman” (1969) in the posthumous publication of On Certainty. This essay explores whether or not this version of the history of Newman's philosophical reception rings true – exploring whether or not the reference to “H Newman” really marks a watershed for Newman's philosophical legacy.
Sustainability in critical care practice: A grounded theory study
Authors: Baid Heather , Richardson Janet , Scholes Julie , Hebron Clair 
Published: December 2019

AbstractBackgroundSustaining high‐quality, critical care practice is challenging because of current limits to financial, environmental, and social resources. The National Health Service in England intends to be more sustainable, although there is minimal research into what sustainability means to people working in critical care, and a theoretical framework is lacking that explains the social processes influencing sustainability in critical care.Aims and objectivesThis study aimed to explain the concept of sustainability from the perspective of practitioners caring for critically ill patients.DesignThe qualitative research followed a Charmazian constructivist grounded theory approach, including concurrent data collection and interpretation through constant comparison analysis.MethodsIn‐depth interviews were conducted online or by telephone with 11 health care professionals working in critical care in the South of England (8 nurses, 2 physiotherapists, and 1 technician). Schatzman's dimensional analysis and Straussian grounded theory techniques supplemented the data analysis.ResultsSustainability was defined as maintaining financial, environmental, and social resources throughout the micro, meso, and macro systems of critical care practice. The most pertinent social process enabling sustainability of critical care was satisficing (satisfaction of achieving a goal of quality care while sufficing within the limits of available resources). Increased satisficing enabled practitioners to fulfil their sense of normative, responsible, sustainable, and flourishing practice. Satisficing was bounded by the cognitive and environmental influences on decisions and an ethical imperative to ensure resources were used wisely through stewarding.ConclusionsAn explanation of the concept of sustainability and significant social processes, in relation to critical care, are presented in a theoretical framework, with implications for how financial, environmental, and social resources for critical care practice can be maintained.Relevance to clinical practiceThis theory offers clinicians, managers, educators, and researchers a definition of sustainability in critical care practice and provides a structured approach to addressing critical care sustainability issues.
Neoadjuvant dose‐modified docetaxel in squamous cell carcinoma of the head and neck: A phase 3 study
Authors: Sun Yan , Guo Wei , Bai Yuxian , Ge Minghua , Hu Chaosu , Wu Shaoxiong , Hao Junfang , Gao Ming , Pan Jianji , Dong Pin , Wu Yunong , Liang Houjie , Wei Qichun , Zhong Meizuo , Lu Taixiang 
Published: December 2019

AbstractObjectiveTo evaluate the efficacy and safety of dose‐modified docetaxel plus cisplatin and 5‐fluorouracil (TPF) in Chinese patients with squamous cell carcinoma of the head and neck (SCCHN).Materials and methodsThis Phase III, open‐label, multi‐center study included Chinese adults with previously untreated TNM Stage III or IV SCCHN (NCT00995293). Patients were randomized (1:1) to induction chemotherapy with TPF (docetaxel 60 mg/m2 and cisplatin 60 mg/m2 on day 1 and 5‐FU 750 mg/m2 per day continuous IV infusion on days 1–5) or PF (cisplatin 75 mg/m2 on day 1 and 5‐FU 750 mg/m2 per day on days 1–5) every 3 weeks for 3–4 cycles. The primary endpoint was progression‐free survival (PFS).ResultsMedian PFS in the TPF (n = 108) and PF (n = 111) groups was 400 days and 342 days (HR = 0.75; 95% CI, 0.53─1.06; p = .227), respectively. Overall response rate was higher for TPF versus PF (76.3% vs. 52.9%; p = .001), although this equalized following radiotherapy (75.0% vs. 73.9%). In the TPF and PF groups, ≥1 treatment‐emergent adverse event was experienced by 104 (94.5%) and 110 (93.2%) patients, respectively.ConclusionAdding dose‐modified docetaxel to PF did not significantly improve PFS but may increase anti‐tumor activity in Chinese patients with locally advanced SCCHN.
Donor‐to‐recipient weight ratio is a risk factor for hepatic artery thrombosis after whole‐liver transplantation in children under 25 kg
Authors: Kim Stephanie S. , Ramos‐Gonzalez Gabriel , Staffa Steven J. , Labib Zahra , Kim Heung Bae , Vakili Khashayar 
Published: December 2019

AbstractHepatic artery thrombosis (HAT) following pediatric liver transplantation increases morbidity and risk of graft failure. We performed a retrospective chart review of all patients who underwent deceased‐donor liver transplantation from August 2002 to July 2016. Multi‐organ transplant recipients were excluded. We examined the incidence of HAT at our institution and sought to identify associated donor or recipient risk factors. A total of 127 deceased‐donor liver transplant patients with a median age of 1.7 years (IQR 0.67‐6.7) were identified. Of those, 14 developed HAT, all weighing under 25 kg. Among 100 patients under 25 kg, whole‐liver graft recipients had an odds ratio of 3.98 (95% confidence interval [CI]: 1.03, 15.34; P = .045) for developing HAT compared with split‐liver graft recipients. Within the whole‐liver recipient group under 25 kg, 11 patients developed HAT with a median donor‐to‐recipient ratio (DRWR) of 0.9 (IQR: 0.7‐1.2) compared with a median DRWR of 1.4 (IQR: 1.1‐1.9) for those who did not develop HAT. Multivariate analysis showed DRWR to be an independent risk factor for HAT in patients weighing under 25 kg who received whole organ grafts, with an odds ratio of 3.89 (95% CI: 1.43, 10.54; P = .008) for each 0.5 unit decrease in DRWR. Our results suggest that in recipients under 25 kg 1) split‐liver grafts may have a lower rate of HAT and 2) selecting whole organ donors with a higher DRWR may decrease the incidence of HAT.