bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dungeon Boogie (2020)
Authors: Morales Ruiz Ana 
Published: November 2020

La generación de los nacidos entre 1980 y 1999, los llamados millenials somos los primeros nativos de la era digital. Hemos vivido una infancia híbrida entre lo analógico y lo virtual.
Hoy día mi generación acude a esta infancia compartida en busca de consuelo. En la producción millennial artística y en la extrartística (como pueden ser los memes) aparece un constante exhibicionismo irónico de lo mal que va nuestra vida. También se hace cada vez más común lo que Eloy Fernández Porta describe como “El artista posmoderno como nostálgico falso” que se dedica a recrear un pasado inexistente por medio de signos, residuos y reliquias.
En éste artículo revisito mi último proyecto expositivo, Dungeon Boogie, una muestra realizada en febrero de 2020 en la sala de exposiciones de la Facultad de Bellas Artes de Málaga. Lo analizo sirviéndome de la figura de ese nostálgico falso que confecciona y atesora un pasado que nunca existió. El proyecto se edifica mediante una metodología multidisciplinar en la que conviven medios como la cerámica, el vídeo, el videojuego, la instalación, la escultura o la moda que se ponen en relación con la infancia híbrida (analógica-digital) de nuestra generación. A su vez, conecto el proyecto con otros artistas coetáneos que también operan de manera similar, jugando a ser ciber-arqueólogos, como Molly Soda, Emma Pryde o Indoorpet.
Effect of vertical malocclusions on root crown ratio of maxillary teeth-A cross-sectional radiographic study
Authors: GVD Harsha , CV Padmapriya , Kumar Arunachalam Siva , DPK Varma , Chakravarthy Vegesna Goutham 
Published: November 2020

Root resorption is the loss of apical root tissue which is implicated by decrease in root-crown ratio. It usually effects from external surface to pulp chamber if not identified in the early stage. Several natural conditions place roots at risk of resorption without any pathology. Knowing the pressure or etiology of the resorption will help the orthodontist in the treatment aspect. To date literature regarding root resorption due to various malocclusions is deplete in Indian population. To measure and assess the root crown ratios of maxillary incisors with vertical malocclusions, deleterious habits, and validate by two different radiographic techniques.90 Patients enrolled for the orthodontic treatment were allocated to three groups - open bite, deep bite & control groups and were subdivided based on nail biting habit. Panoramic radiographs, Periapical radiographs (by paralleling technique) for maxillary incisors (360 teeth) were taken and traced. Length of the root & crown were assessed and root crown ratios were calculated and the results substituted to statistics using SPSS. Comparison of Root-crown ratios in vertical malocclusions, revealed statistically significant (P &#60; 0.001) differences in Open bite group for all maxillary incisors in both panoramic and periapical radiographs. No statistical significant differences were found in the deep bite group. Significant association was found between nail biting habit and Root-crown ratio. Gender predilection was found to be absent.Decreased Root- crown ratios were observed in open bite patients. Nail biting patients show significant root resorption. Both panoramic radiographs and periapical radiographs with paralleling technique can be used for assessing root resorption.
The effectiveness of chemicals used in the process of transmitting crude oil from the well to the processing plant
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Bęben Dariusz 
Published: November 2020

Chemicals are added to crude oil to ensure that it flows from the well to the processing plant. Depending on the composition of the reservoir fluids being extracted (crude oil, reservoir water, natural gas), paraffin may be separated from the crude oil, hydrates may be formed from reservoir water and natural gas, and the combination of reservoir water and crude oil may form an emulsion. Those situations should be avoided to ensure continuous flow from the wellbore to the processing plant. To this end, chemicals, paraffin inhibitors, hydrate inhibitors, and demulsifiers are used. Based on the literature on the subject and on the author’s own experience from observing technological processes, research methods were proposed to assess the effectiveness of chemicals used to ensure the continuity of crude oil flow. The crude oil selected for the tests was characterised by a high content of paraffins, asphaltenes, chloride ions, and water. To determine the onset of paraffin precipitation, tests were conducted based on a change in viscosity and a coupon method – determining the weight gain on a coupon to check the effectiveness of a paraffin inhibitor. The rate of emulsion separation was evaluated in separating funnels. The water released from crude oil often leaches the salt contained within it. Various demulsifiers were used to investigate the separation of emulsions and the purification of oil from salts; silicone demulsifiers in particular were considered. To determine the change in the amount of salt in crude oil, a conductometric measurement was performed. The amount of demulsifier used for phase separation was determined by changing the surface tension. The proposed solution for the use of chemicals to transport and purify crude oil yields tangible economic benefits. The article summarises the research procedures and presents the results for selected crude oil and chemicals.
Combination of pre-fermentative and fermentative strategies to produce Malbec wines of lower alcohol and pH, with high chemical and sensory quality
Authors: Fanzone Martín , Sari Santiago E. , Mestre María V. , Catania Anibal A. , Catelén María J. , Jofré Viviana P. , González-Miret María L. , Combina Mariana , Vazquez Fabio , Maturano Yolanda P. 
Published: November 2020

The climatic conditions in some wine regions imply in many cases the important delay in the harvest date to achieve an appropriate phenolic maturity in red grape varieties, leading to wines with high pH and alcohol content. This problem, associated with low acceptation for some consumers and chemical/microbial instability, can be addressed from a viticultural, oenological, or microbiological level. The present study aimed to provide a technological alternative, combining vintages blending and inoculation of native yeasts, for reducing simultaneously the alcohol content and the pH of Malbec wines without altering the chemical and sensory quality. Sauvignon blanc grapes harvested at the beginning of ripening (2017 season) were employed to obtain a wine with high acidity and low alcohol content (LW), that was blending with Malbec grapes of full phenolic maturity. Malbec grapes were harvested at two different moments (1H, 13.0 % v/v; 2H, 14.5 % v/v, probable alcohol), and elaborated following a standard protocol. From 2H, a part of the grape juice was removed and replaced with LW as a strategy for alcohol reduction (2RW). Consequently, it was obtained nine wines by triplicate combining 1H, 2H, 2RW musts with three fermentative strategies: CI, co-inoculation of Hanseniaspora uvarum BHu9/Saccharomyces cerevisiae BSc114 native yeasts; NS, S. cerevisiae BSc114 native yeast; and CS, S. cerevisiae EC 1118 commercial yeast. We found that 2RW wines, fermented with different yeast strains, showed similar levels of total phenols, tannins, anthocyanins, and polymeric pigments concerning control wines (2H). In all cases, those wines presented greater phenolic potential compared to wines from 1H. At the same time, the pre-fermentative strategy of vintages blending produced wines with 1.4 % v/v less alcohol than 2H wines, also achieving a pH decrease of 0.3 units. Combined treatments with native strains, especially as single inoculum (2RW–NS), were the most efficient in reducing both parameters, showed higher tannins, anthocyanins levels, and colour saturation, without affecting the sensory quality, in terms of aromas and mouthfeel. In conclusion, the strategies proposed could be simple and economic tools, for red wines production with low alcohol content, and high chemical and organoleptic quality, capable of competing and satisfying market needs.
Tauhid and Taqwa: The Soul in the COSO-ERM Framework -An Imaginary Research Dialogue-
Authors: Djasuli Mohamad 
Published: November 2020

This research is an imaginary dialogue between two internal auditors of a state university. They are called as a religious senior auditor and a junior auditor. The imaginary dialogue used spirituality in order to avoid misunderstanding and heartache of each other. Both of them discuss current issues in regard to internal control as a soul and foundation to achieve the organization's objectives. This research is to discuss the concept of internal control built by the Committee of Sponsoring Organizations of the Treadway Commission (COSO), whether is it enough to be the guardian system or is there missing elements that should be discovered? They will use the COSO-ERM (Entreprises Risk Management) as the modification of COSO, as the internal control world considers risk management is the key to prevent an organization from failure nowadays. Finally, this research offer a deconstruction of the COSO-ERM framework to become The Tauhid Taqwa-COSO-ERM Framework with Tauhid and Taqwa as the most foundation of all things in the framework especially for the human as the operator in all level.Keywords: tauhid, taqwa, COSO-ERM, and internal control
Presenilin 2 N141I mutation induces hyperactive immune response through the epigenetic repression of REV-ERBα
Authors: Nam Hyeri , Lee Younghwan , Kim Boil , Lee Ji-Won , An Hyun-Kyu , Chung Kyung Min , Park Youngjin , Hong Jihyun , Kim Kyungjin , Kim Eun-Kyoung , Choe Han Kyoung , Yu Seong-Woon 
Published: November 2020

Abstract
Hyperimmunity drives the development of Alzheimer disease (AD). The immune system is under the circadian control, and circadian abnormalities aggravate AD progress. Here, we investigated how an AD-linked mutation deregulates expression of circadian genes and induces cognitive decline using the knock-in (KI) mice heterozygous for presenilin 2 (Psen2) N141I mutation. This mutation causes overproduction of clock-controlled cytokines through the epigenetic repression of the clock protein REV-ERBα in innate immune cells, which show normal circadian period but lower amplitude. The KI/+ mice displayed normal circadian behaviour patterns, but were vulnerable to an otherwise innocuous, mild immune challenge. The antipsychotic chlorpromazine restored the REV-ERBα level and prevented the overexcitation of innate immune cells and cognitive decline in KI/+ mice. These results highlight a new pathogenic link between this AD mutation and immune cell-intrinsic circadian alteration through the epigenetic suppression of REV-ERBα.
Control of hysteretic sorption of flexible MOF for practical acetylene safe storage
Authors: Bonneau Mickaele , Lavenn Christophe , Sugimoto Kunihisa , Legrand Alexandre , Ogawa Tomofumi , Coudert François-Xavier , Réau Regis , Otake Ken-ichi , Kitagawa Susumu 
Published: November 2020

Abstract
Safe managing and storage of explosive gas, such as acetylene, is essential for industries. The practical pressure and temperature regime is quite narrow for acetylene, and the optimization by complete release of saturated gas remains challenging to control. Here, a novel approach to narrow the pressure range of gas introduction and release for the storage of unstable and pressure-sensitive gas substance is reported. Flexible metal–organic frameworks (MOFs) are expected to be an excellent storage adsorbent owing to their gated adsorption/desorption behavior. However, developing such a system in a practical and narrow pressure range remains difficult. Here, we demonstrate that the gate-opening and closing pressures of a solid solution type based on interpenetrated MOF-508 can be optimized by tuning the deformation energy of the framework and the energy of host–guest interactions. These energies were adjusted by changing the functional group on the MOF ligands and its ratio in the mixed-ligand system. The filling and release of acetylene in the practical pressure regions of up to 180 kPa leads to an on-demand porous material for acetylene storage with an usable volumetric capacity of 106 v/v under mild temperature (273–298 K) and pressure (70–120 kPa).
Histopathological Analysis of Mucinous Breast Cancer Subtypes and Comparison with Invasive Carcinoma of no Special Type.
Authors: Budzik Michał Piotr , Fudalej Marta Magdalena , Badowska-Kozakiewicz Anna Maria 
Published: November 2020

Abstract
BackgroundMucinous breast cancer (MBC) is a rare histological type of breast cancer characterized primarily by the production and extracellular presence of mucin and it is usually associated with a better prognosis than other invasive breast neoplasms. Because of the low prevalence, MBC biology is not well understood. MethodsThe aim of the present study was to introduce the last 2-year experience regarding MBC pathological diagnostics in our clinical center and comparison of the obtained data with invasive breast carcinoma of no special type (NST) comprising the most common invasive breast cancer. ResultsWe identified 24 MBC cases representing 3.09% of all 766 invasive breast cancers, including 15 cases of pure type and 9 mixed MBCs. The median MBC patients’ age at presentation was 65.5 years. In comparison to NST, MBC presented a higher T stage with a statistically larger tumor median size, although lower regional lymph node involvement, tumor histological grade and TNM stage. ConclusionMBC is a rare type of breast cancer accounting for about 4% of all diagnosed breast cancers. Our findings are consistent with those published in recent years and show significant differences between MBC and NST cancer patients and also highlight differences between pure and mixed MBC emphasizing the essence of their differentiation. MBC is associated with a better long-term prognosis than NST and is characterized by the less aggressive biological behavior expressed through favorable clinicopathologic features in terms of tumor grade, regional lymph node involvement and hormone receptor status.
Analysis of Influencing Factors of Residual Low Back Pain After PVP
Authors: Qin Fengwei , Wang Shuai , Zhang Wencai , Chen Wen , Feng Yonghui , Zhang Zhaofei , Xie Chunliang , Liu Donghua , Zhang Sineng , Liang Jie 
Published: November 2020

Abstract
Study design: Retrospective studyObjective: The purpose of this paper is to explore the possible risk factors for residual low back pain after PVP and to analyze their correlation.Method: A retrospective study was conducted on 1120 patients hospitalized for OVCF and treated with PVP between from July 2015 to June 2019 at our Hospital. Baseline, clinical and surgical data were collected to analyze the factors associated with residual low back pain after PVP.Results: 61 patients complained of residual low back pain, and the prevalence was 5.4%. Among the observed indexes included, there were significant differences in preoperative Thoracolumbar fascia injury (TFI), a liquefaction signal on magnetic resonance imaging (MRI) of the affected vertebrae, the number of responsible vertebrae and the distribution of bone cement between the two groups (P<0.05). Multivariate analysis revealed that preoperative TFI (OR=5.378, 95% CI: 1.713~16.888, P=0.004), a liquefaction signal on MRI of the affected vertebrae (OR=6.111, 95% CI：1.898~19.673, P=0.002), the number of responsible vertebrae (OR=0.098, 95% CI: 0.039~0.249, P=0.004), and the distribution of bone cement (OR=0.253, 95% CI: 0.079~0.810, P=0.021) were risk factors for residual low back pain after PVP.Conclusion: TFI, a liquefaction signal on MRI of the affected vertebrae, the number of responsible vertebrae and the distribution pattern of bone cement may be risk factors for residual low back pain after PVP.
NRAGE, a potential biomarker, induces radioresistance in two- and three-dimensional culture and confers poor prognosis in esophageal squamous cell carcinoma
Authors: Zhou Huandi , Wang Guohui , Xiao Zhiqing , Yang Yu , Gao Chen , Han Xuetao , Sun Wei , Hou Liubing , Liu Junling , Xue Xiaoying 
Published: November 2020

Abstract
Background

To explore the mechanism of NRAGE enhancing radioresistance of ESCC in 2D and 3D levels.
Methods

Stably NRAGE-overexpressed ESCC cells and 3D-printing models for ESCC cells were established. Then, cellular malignancy indexes, such as cell morphology, proliferation, radioresistance, motility, apoptosis, cell cycle, and proteins of the Wnt/β-catenin pathway, were compared between radioresistant and its parental cells in 2D and 3D levels. Additionally, 44 paraffin ESCC specimens with radical radiotherapy were selected to examine NRAGE and β-catenin protein expression and analyze the clinical correlation.
Results

Experiments in 2D culture showed that Eca109/NRAGE cells’ morphology was more irregular, elongated spindle-shaped and disappeared polarity. It obtained faster growth ability, stronger resistance to irradiation, enhanced motility, reduced apoptosis ratio and cell cycle rearrangement. Moreover, Western blot results showed β-catenin, p-Gsk-3β and CyclinD1 expressions were induced, while p-β-catenin and Gsk-3β expressions decreased in Eca109/NRAGE cells. Experiments in the 3D-printing model showed Eca109/NRAGE cell-laden 3D scaffolds had the advantage on growth and spheroiding according to the brigbtfield observation, scanning electron microscopy and Ki-67 IHC staining, and higher expression at the β-catenin protein. Clinical analysis showed that NRAGE expression was higher in tumor tissues than in control tissues of ESCC patients from the Public DataBase. Compared with radiotherapy effective group, both NRAGE total and nuclear and β-catenin nuclear expressions were significantly upregulated from ESCC specimens in invalid group. Further analysis showed a positive and linear correlation between NRAGE nuclear and β-catenin nuclear expressions. Additionally, results from univariate and multivariate analyses revealed NRAGE nuclear expression could serve as a risk factor for ESCC patients receiving radical radiotherapy.
Conclusion

ESCC cells with NRAGE nuclear accumulation demonstrated greater radioresistance, which may be related to the activation of the Wnt/β-catenin signaling pathway. It indicated that NRAGE nuclear expression was a potential biomarker for monitoring radiotherapeutic response.
Development of a Structure-Validated Hypersexuality Scale in Chinese University Students
Authors: Jia Yanli , Shao Xu , Shen Chanchan , Wang Wei 
Published: November 2020

Abstract
BackgroundHypersexuality is associated with many psychiatric disorders and creates enormous burden for the affected individual, family and society. However, there is no structure-validated questionnaire available to measure hypersexuality in a comprehensive way, especially in aspects of emotion and stress. MethodsWe designed a matrix of 72 items related to hypersexual experience, and we invited 282 heterosexual university students who experienced hypersexuality at least once life-long to answer the matrix. ResultsThrough exploratory factor analyses and exploratory structural equation modeling, we constructed a Hypersexuality Scale, with a satisfactory model structure of five factors (or scales, 4 items for each scale) of hypersexuality, and named them as the Negative Impact, Emotional Coping, Uncontrolled Behavior, Post-sex Regret, and Increased Interest. Most inter-correlations of these factors were significant but in low or medium levels in all participants. Male students scored significantly higher on Negative Impact and Increased Interest than females did. ConclusionsThe five scales described in this study might help to understand hypersexuality, and the Hypersexuality Scale might be applied to the clinical conditions related to hypersexuality.
Database selection and data gathering methods in systematic reviews on qualitative research regarding diabetes mellitus - An explorative study
Authors: Justesen Tobias , Freyberg Josefine , Schultz Anders Nikolai Ørsted 
Published: November 2020

Abstract
Background

Systematic reviews (SRs) are considered one of the most reliable types of studies in evidence-based medicine. This relies on a comprehensive and systematic search by choosing ideal data gathering methods including selection of databases. The aim of this study was to investigate which combination of databases results in the highest recall of references when conducting SRs on qualitative research regarding diabetes mellitus. Furthermore, we aimed to investigate the current use of databases and the importance of other sources for data collection.
Methods

23 SRs (published between the year 2010 and 2019) on qualitative research regarding diabetes mellitus were located through searching PubMed and met the inclusion criteria. Data, including number of databases searched, names of databases, use of additional data sources and use of information specialists were collected for each SR. The SRs concluded a total of 459 unique, qualitative references on diabetes mellitus. These references were systematically hand searched in the five most searched databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE, PsycINFO, Embase and PubMed.
Results

The SRs searched four databases on average (range two to eight). CINAHL was the most searched database, (19 of the 23 SRs). Two SRs mentioned the involvement of an information specialist and 16 of 23 (70%) SRs searched reference lists of included references, which on average resulted in 16% more references being included. A total of 36 (8%) references were found only in one of the five databases, with CINAHL retrieving the highest number of unique references. Searching the combination of the three databases PubMed, Embase and CINAHL resulted in an overall recall rate of 99.3%, while adding PsycINFO increased overall recall to 99.8%.
Conclusions

We recommend combining the searches of CINAHL, PubMed, Embase and PsychINFO, and to involve an information specialist to ensure high recall rates, when conducting SRs on qualitative research regarding diabetes mellitus. Especially CINAHL is highly relevant and important to use when searching for qualitative research.