bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical and biological study on the effect of yoghurt on most common consumed ready meat products
Authors: Alsuhaibani Amnah Mohammed 
Published: December 2024

Basterma is characterized as fresh non cooked and manufactured under the addition of salt, phosphate, nitrite, ascorbic acid, sugars, and different seasoning(1). Sausages are very common and popular processed meat products manufactured from lower-value trimmed meat to produce a higher-value product(2). Basterma is fermented during the partially drying process under climatic conditions(3,4). Nitrates and nitrites are chemicals that can be found naturally in our food, water and in plant nutrients. Nitrites cause a color reaction in the meat and add an appealing pink color to cooked products(5). Nitrite prevents the growth of a harmful bacterium called Clostridium botulinum and other spoilage bacteria(6). This study was to estimate nitrite and nitrate in basterma and sausage and the effects of yoghurt in lowering the side effect of nitrite and nitrate at heavy consumption of some ready-made meat products.The ready-made meat products and yoghurt were bought from different supermarkets in Riyadh/KSA. Thirty-five male albino rats, weighing 110 ± 6 g was provided from experimental animal’s center in Medicine collage of KSU in Riyadh. The experimental diet formed from basal diet but basterma and sausage were added to basal diet instead of casein. The nitrite and nitrate contents were determined in experimental readymade-meat products immediately after purchase in triplicate by rapid method of improved accuracy according to Follett and Ratcliff method. Rats fed on basal diet for a week as adaptation period in wire cages under the normal laboratory conditions. Food intake was calculated daily, and the body weight gain was recorded weekly. Collected data are expressed as mean ± SE. Statistical analysis was done by using analysis of variance (ANOVA) followed by student’s t-test and P values of 5% and less were significant.The results of ALT, AST, ALP and γ GT of the experimental rat groups noticed that a non-significant higher in values of AST, AST and γ GT and a non-significant lower in values ALT and ALP compared to rat group which fed on basterma. Rat groups which fed on basterma with yoghurt, sausage with yoghurt, and both basterma and sausage with yoghurt showed a significant decrease in liver enzymes concentration in comparison with rat groups which fed on either basterma or sausage but showed non-significant difference among these groups. Also, results presented a significant decrease in creatinine, urea, and uric acid concentration in comparison with rat groups which fed on either basterma or sausage. Likewise for the results of total protein, albumin, and globulin for the same rat groups.It can be recommended from this study that heavy meat products consumer should consume yoghurt to lower side effects of meat preservative as nitrite and nitrate.
Predictors of outcome following psychological therapy for depression and anxiety in an urban primary care service: a naturalistic Bayesian prediction modeling approach
Authors: Hodsoll John , Strawbridge Rebecca , King Sinead , Taylor Rachael W. , Breen Gerome , Grant Nina , Grey Nick , Hepgul Nilay , Hotopf Matthew , Kitsune Viryanaga , Moran Paul , Tylee André , Wingrove Janet , Young Allan H. , Cleare Anthony J. 
Published: December 2024

AbstractBackgroundEngland's primary care service for psychological therapy (Improving Access to Psychological Therapies [IAPT]) treats anxiety and depression, with a target recovery rate of 50%. Identifying the characteristics of patients who achieve recovery may assist in optimizing future treatment. This naturalistic cohort study investigated pre-therapy characteristics as predictors of recovery and improvement after IAPT therapy.MethodsIn a cohort of patients attending an IAPT service in South London, we recruited 263 participants and conducted a baseline interview to gather extensive pre-therapy characteristics. Bayesian prediction models and variable selection were used to identify baseline variables prognostic of good clinical outcomes. Recovery (primary outcome) was defined using (IAPT) service-defined score thresholds for both depression (Patient Health Questionnaire [PHQ-9]) and anxiety (Generalized Anxiety Disorder [GAD-7]). Depression and anxiety outcomes were also evaluated as standalone (PHQ-9/GAD-7) scores after therapy. Prediction model performance metrics were estimated using cross-validation.ResultsPredictor variables explained 26% (recovery), 37% (depression), and 31% (anxiety) of the variance in outcomes, respectively. Variables prognostic of recovery were lower pre-treatment depression severity and not meeting criteria for obsessive compulsive disorder. Post-therapy depression and anxiety severity scores were predicted by lower symptom severity and higher ratings of health-related quality of life (EuroQol questionnaire [EQ5D]) at baseline.ConclusionAlmost a third of the variance in clinical outcomes was explained by pre-treatment symptom severity scores. These constructs benefit from being rapidly accessible in healthcare services. If replicated in external samples, the early identification of patients who are less likely to recover may facilitate earlier triage to alternative interventions.
Maternal underestimations and overestimations of their infants’ word comprehension: effects on mothers’ verbal input and infants’ receptive vocabulary
Authors: Ertaş Sura , Küntay Aylin C. , Aktan-Erciyes Aslı 
Published: December 2024

Abstract
Infants’ language is often measured indirectly via parent reports, but mothers may underestimate or overestimate their infants’ word comprehension. The current study examined estimations of mothers from diverse educational backgrounds regarding their infants’ word comprehension and how these estimations are associated with their verbal input and infants’ receptive vocabulary at 14 months. We compared 34 infants’ looking-while-listening (LWL) performances with the mothers’ Turkish Communicative Development Inventory (TCDI) reports to calculate the mothers’ overestimation and underestimation. During free-play sessions, we assessed the mothers’ number of words, number of clauses, lexical diversity, and linguistic complexity. We found that mothers have overestimations and underestimations regardless of their educational background. Crucially, mothers’ only overestimations were positively associated with their number of words and lexical diversity. Mothers’ verbal input was not related to infants’ receptive vocabulary scores. The findings suggest that mothers’ input might be aligned with their estimations of their infants’ language capabilities, which might not reflect the infants’ true performance.
A conceptual model of autonomous ship remote operators' competency
Authors: Kuntasa Tanan , Lirn Taih-Cherng 
Published: December 2024

AbstractThe Shore Control Centre (SCC) is being developed and tested as an autonomous ship vessel with remote control. However, since the International Convention on Standards of Training, Certification and Watchkeeping for Seafarers (STCW) regulation's competency standard has yet to be altered, it must be revised and modified. Therefore, this study aims to define the competency of remote operators on an autonomous ship from ashore and develop a conceptual model of remote operators' competency. This study used both primary data by interviewing executives from four groups of maritime experts, and secondary data from academic databases, IMO, classification society and maritime companies. Academic databases are employed to conclude the academicians' view on remote operators’ (ROs’) competency and the other data sources are used to conclude the industrial view on the RO's competency. The content analysis technique was used to determine the presence of keywords or concepts from secondary data and develop a conceptual model. The study's findings present four main dimensions to indicate the development of future training and development programs for RO officers: navigation, cargo handling and stowage, controlling the ship's operation and care for persons onboard, and information technology; and present 45 competencies of ROs for managing autonomous ships from ashore, which a conceptual model can explain.
Conflicting Legal Perspectives on the Establishment of Kingdom of Serbs, Croats, and Slovenes
Authors: Ivašković Igor 
Published: December 2024

Abstract
The analysis delves into the complex legal intricacies surrounding the establishment of South Slavic state entities post-World War I, as international law of the time didn't fully encompass modern legal instruments defining international relations subjects. Nonetheless, legal arguments affirm the statehood of the State of SCS, formed within the former Austro-Hungarian Empire through legitimate representative bodies, despite lacking formal international recognition. The Croatian state transitioned governance under the National Council of SCS without abolishing its institutions. The analysis of the “December 1st Act” highlights procedural violations during the forming of the Kingdom of SCS, indicating a deviation from authorized scope, though it did not render the new state's government illegitimate. The negotiating process favored Serbian authorities, evident in the “Vidovdan” Constitution, yet it doesn't suffice to claim the State of SCS was annexed by the Kingdom of Serbia. Legally, there's little ambiguity, but disputes in international legal rulings and interpretations uncover internal political tensions and external pragmatic influences.
Influence of pre-existing maternal diabetes mellitus on fetal myocardial performance index and systolic-to-diastolic duration ratio: a prospective cohort study
Authors: Peixoto Alberto Borges , Bravo-Valenzuela Nathalie Jeanne Magioli , Rolo Liliam Cristine , Mattar Rosiane , Moron Antonio Fernandes , Tonni Gabriele , Araujo Júnior Edward 
Published: December 2024

AbstractObjective:To evaluate the influence of pre-existing maternal diabetes mellitus on fetal myocardial performance index and systolic-to-diastolic duration ratio.Methods:Prospective cohort study included 179 pregnant women between 20 and 36w6d, divided into 3 groups: Group 1 (120, normal), Group 2 (31, type 1 diabetes mellitus), and Group 3 (28, type 2 diabetes mellitus). Systolic-to-diastolic duration ratio was calculated as the sum of isovolumic contraction time and ejection time divided by the sum of isovolumic relaxation time and ventricular filling time. Spectral Doppler was used to assess left ventricle systolic-to-diastolic duration ratio. Tissue Doppler was used to assess right ventricular filling time. Using spectral Doppler, left ventricle myocardial performance index was calculated as the sum of isovolumic contraction time and isovolumic relaxation time divided by ejection time.Results:Pre-existing maternal diabetes mellitus had a significant influence on fasting glucose levels (p < 0.001), left ventricle isovolumic contraction time (p < 0.001), left ventricle ejection time (p = 0.025), and left ventricle myocardial performance index (p < 0.001). Group 2 had higher left ventricle isovolumic contraction time (0.036 vs. 0.031 sec, p = 0.001) and left ventricle myocardial performance index (0.487 vs. 0.453, p = 0.003) compared with Group 1. Group 3 showed higher left ventricle myocardial performance index (0.492 vs. 0.449, p = 0.006) and lower left ventricle ejection time (0.161 vs. 0.169 sec, p = 0.038) than Group 1. Left ventricle systolic-to-diastolic duration (p = 0.704), right ventricle systolic-to-diastolic duration ratio’ (p = 0.757), left ventricle isovolumic contraction time (p = 0.163), left ventricle ejection time (p = 0.093), and left ventricle myocardial performance index (p = 0.087) were not useful parameters in predicting composite neonatal outcomes.Conclusion:Pre-existing maternal diabetes mellitus had significant influence on fetal left ventricle myocardial performance index, but no effect on systolic-to-diastolic duration ratio. Systolic-to-diastolic duration ratio was not useful in predicting adverse perinatal outcomes.
Late Age at First Birth is a Protective Factor for Preterm Labor and Delivery: The Evidence From the Genetic Study
Authors: Zou Jinghui , Li Cheng , Wu Hangyu , Xue Aijiao , Yan Lulu , Zhang Yisheng 
Published: December 2024

AbstractThe objective of this study was to investigate the genetic link between the age at first birth (AFB) and the occurrence of preterm labor and delivery, utilizing Mendelian randomization (MR) data alongside genomewide association analysis (GWAS). We obtained AFB-related GWAS summary data from the European Bioinformatics Institute database and preterm labor and delivery data was sourced from the FinnGen Consortium. The study considered AFB as exposure variables, with the incidence of preterm labor and delivery serving as the outcome variable. Several MR analysis methods, such as inverse-variance weighted (IVW), MR Egger, weighted median, simple, and weighted mode were utilized. Besides MR-Egger intercepts, Cochrane’s Q test evaluated heterogeneity in the MR data, while MR-PRESSO test checked for horizontal pleiotropy. To assess the association’s sensitivity, A leave-one-out approach was utilized to evaluate the sensitivity of the association. The IVW analysis validated that AFB is an independent risk factor for preterm labor and delivery (p < .001). Horizontal pleiotropy was unlikely to bias causality (p > .05). The likelihood of horizontal pleiotropy affecting causality was low (p > .05), and there was no indication of heterogeneity among the genetic variants (p > .05). Ultimately, a leave-one-out analysis confirmed the stability and reliability of this correlation. Our research indicated that AFB is a protective factor for preterm labor and delivery. Further research is required to clarify the possible mechanisms.
Evaluating How Historical Climate Change Affected a Heavy Snowfall Event in Northern Japan in Mid‐December 2021 Using Two Pseudo Global Warming Methods
Authors: Tamura K. , Sato T. 
Published: December 2024

AbstractIn mid‐December 2021, heavy snowfall occurred when an extratropical cyclone passed around Hokkaido, northern Japan. In this study, we investigated the contribution of historical climate change to the heavy snowfall event using large ensemble simulation data sets and two pseudo global warming (PGW) methods. We classified the large ensemble simulation data sets by the pressure pattern and identified the extratropical cyclone event. Composite analyses reveal that the development of the extratropical cyclone can be attributed to historical climate change. We ran the PGW method with the classified meteorological data as the input data and found that the development of the extratropical cyclone resulted in enhanced water vapor transport and intensified local convergence in the lower troposphere, causing heavy precipitation. We also found that oceanic warming made a minimal contribution to the precipitation in this event. These findings highlight the importance of considering historical changes in event‐specific synoptic‐scale atmospheric conditions when evaluating the contributions of climate change to extreme events.
Effect of herbal toothpaste on the colour stability, surface roughness, and microhardness of aesthetic restorative materials—an in vitro study
Authors: Hazra Yashodhara , Rao Arathi , Natarajan Srikant , Srikrishna Suprabha Baranya 
Published: December 2024

Abstract
Objective
To evaluate the in vitro effects of two commonly used commercial herbal toothpastes (Dabur Meswak and Patanjali Dant Kanti) on the colour stability, surface texture, and microhardness of two commonly used aesthetic restorative materials, i.e., nanofilled composite and resin-modified glass ionomer cement (NFC and RMGIC).

Materials and methods
The samples were brushed twice daily using two herbal toothpastes, Dabur Meswak (Dabur India Ltd) and Patanjali Dant Kanti (Patanjali Ayurved Ltd, India) and powered toothbrush. Atomic force microscopy, spectroscopy, and digital micro hardness testing were used to estimate the changes in the surface roughness, colour change, and hardness of the samples, respectively, at baseline and after six months.

Results
Regarding colour change, a statistically significant difference (P < 0.05) was observed between baseline and six months in both the RMGIC and NFC for both herbal toothpastes. Both RMGIC and NFC had higher Ra values when brushed with either toothpaste, indicating a rough surface. The greatest increase in the mean difference in microhardness was observed for the Patanjali Dant Kanti toothpaste samples brushed on both NFC and RMGIC.

Conclusion
In our work, herbal toothpaste increased surface roughness and microhardness and caused colour changes in the two most commonly used aesthetic restorative materials.

Clinical relevance
Herbal toothpastes affect the surface texture of aesthetic dental restorative materials. Dental professionals may need to educate their patients to be cautious regarding the prolonged use of herbal toothpaste.
Understanding rare genetic variants within the terminal pathway of complement system in preeclampsia
Authors: Lokki A. Inkeri , Triebwasser Michael , Daly Emma ,   The FINNPEC Core Investigator Group, Heinonen Seppo , Kajantie Eero , Kere Juha , Kivinen Katja , Pouta Anneli , Kurki Mitja I. , Perola Markus , Auro Kirsi , Salmon Jane E. , Anuja Java , Daly Mark , Atkinson John P. , Laivuori Hannele , Meri Seppo 
Published: December 2024

Abstract
Preeclampsia is a common multifactorial disease of pregnancy. Dysregulation of complement activation is among emerging candidates responsible for disease pathogenesis. In a targeted exomic sequencing study of 609 women with preeclampsia and 2092 non-preeclamptic controls, we identified 14 variants within nine genes coding for components of the membrane attack complex (MAC, C5b-9) that are associated with preeclampsia. We found two rare missense variants in the C5 gene that predispose to preeclampsia (rs200674959: I1296V, OR (CI95) = 24.13 (1.25–467.43), p value = 0.01 and rs147430470: I330T, OR (CI95) = 22.75 (1.17–440.78), p value = 0.01). In addition, one predisposing rare variant and one protective rare variant were discovered in C6 (rs41271067: D396G, OR (CI95) = 2.93 (1.18–7.10), p value = 0.01 and rs114609505: T190I, 0.02 OR (CI95) = 0.47 (0.22–0.92), p value = 0.02). The results suggest that variants in the terminal complement pathway predispose to preeclampsia.
A binary system in the S cluster close to the supermassive black hole Sagittarius A*
Authors: Peißker Florian , Zajaček Michal , Labadie Lucas , Bordier Emma , Eckart Andreas , Melamed Maria , Karas Vladimír 
Published: December 2024

AbstractHigh-velocity stars and peculiar G objects orbit the central supermassive black hole (SMBH) Sagittarius A* (Sgr A*). Together, the G objects and high-velocity stars constitute the S cluster. In contrast with theoretical predictions, no binary system near Sgr A* has been identified. Here, we report the detection of a spectroscopic binary system in the S cluster with the masses of the components of 2.80  ±  0.50 M⊙ and 0.73  ±  0.14 M⊙, assuming an edge-on configuration. Based on periodic changes in the radial velocity, we find an orbital period of 372±3 days for the two components. The binary system is stable against the disruption by Sgr A* due to the semi-major axis of the secondary being 1.59±0.01 AU, which is well below its tidal disruption radius of approximately 42.4 AU. The system, known as D9, shows similarities to the G objects. We estimate an age for D9 of $$2.{7}_{-0.3}^{+1.9}\,\times \,1{0}^{6}$$
2
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7

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0.3

+
1.9

×

1

0

6

yr that is comparable to the timescale of the SMBH-induced von Zeipel-Lidov-Kozai cycle period of about 106 yr, causing the system to merge in the near future. Consequently, the population of G objects may consist of pre-merger binaries and post-merger products. The detection of D9 implies that binary systems in the S cluster have the potential to reside in the vicinity of the supermassive black hole Sgr A* for approximately 106 years.
Perceived and endocrine acute and chronic stress indicators in fibromyalgia syndrome
Authors: Beiner Eva , Hermes Michelle , Reichert Julian , Kleinke Kristian , Vock Stephanie , Löffler Annette , Ader Leonie , Sirazitdinov Andrei , Keil Sebastian , Schmidt Tim , Schick Anita , Löffler Martin , Hopp Michael , Ruckes Christian , Hesser Jürgen , Reininghaus Ulrich , Flor Herta , Eich Wolfgang , Friederich Hans-Christoph , Tesarz Jonas 
Published: December 2024

AbstractFibromyalgia syndrome (FMS) is a chronic disorder characterized by widespread musculoskeletal pain, fatigue and tenderness and closely associated with high levels of stress. FMS is therefore often considered a stress-related disease. A comparative study was conducted with 99 individuals diagnosed with FMS and a control group of 50 pain-free individuals. Stress indicators were classified into three categories: perceived stress assessed using the Perceived Stress Scale, and daily average salivary cortisol and hair cortisol concentrations as indicators of acute and chronic stress levels related to the hypothalamic-pituitary-adrenal axis. Analysis of variance and covariance were used to identify group differences and the influence of covariates age, sex, and body mass index. Correlational analyses further elucidated the relationship between stress indicators and clinical symptoms. Participants with FMS reported significantly higher perceived stress levels than controls (p < .001, ηp2 = 0.3), which were positively correlated with symptom burden (r = .41, p < .001). In contrast, there were no significant differences in the endocrinological stress indicators salivary and hair cortisol between the groups (p > .05), nor were these indicators associated with clinical symptoms. The study highlights the central role of perceived stress in FMS, whereas endocrinological indicators did not differentiate FMS from controls. This finding calls for a nuanced approach to clinical assessment and therapeutic interventions tailored to patients with FMS, emphasizing the management of perceived stressors.
Analysis of polaron pair lifetime dynamics and secondary processes in exciplex driven TADF OLEDs using organic magnetic field effects
Authors: Morgenstern Annika , Weber Dominik , Hertling Lukas , Gabel Konstantin , Schwarz Ulrich T. , Schondelmaier Daniel , Zahn Dietrich R. T. , Salvan Georgeta 
Published: December 2024

AbstractMagnetic field effects (MFEs) in thermally activated delayed fluorescence (TADF) materials have been shown to influence the reverse intersystem crossing (RISC) and to impact on electroluminescence (EL) and conductivity. Here, we present a novel model combining Cole–Cole and Lorentzian functions to describe low and high magnetic field effects originating from hyperfine coupling, the $$\Delta$$g mechanism, and triplet processes. We applied this approach to organic light-emitting devices of third generation based on tris(4-carbazoyl-9-ylphenyl)amine (TCTA) and 2,2′,2″-(1,3,5-benzinetriyl)-tris(1-phenyl-1-H-benzimidazole) (TPBi), exhibiting blue emission, to unravel their loss mechanisms. The quality of the regression function was evaluated using k-fold cross-validation. The scoring was compared to various alternative fitting functions, which were previously proposed in literature. Density functional theory calculations, photoluminescence, and electroluminescence studies validated the formation of a TADF exciplex system. Furthermore, we propose successful encapsulation using a semi-permeable polymer, showing promising results for magnetic field sensing applications on arbitrary geometry. This study provides insights into the origin of magnetic field effects in exciplex-TADF materials, with potential applications in optoelectronic devices and sensing technologies.