bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship Between Depression and the Use of Mobile Technologies and Social Media Among Adolescents: Umbrella Review
Authors: Arias-de la Torre Jorge , Puigdomenech Elisa , García Xavier , Valderas Jose M , Eiroa-Orosa Francisco Jose , Fernández-Villa Tania , Molina Antonio J , Martín Vicente , Serrano-Blanco Antoni , Alonso Jordi , Espallargues Mireia 
Published: July 2020

BackgroundDespite the relevance of mobile technologies and social media (MTSM) for adolescents, their association with depressive disorders in this population remains unclear. While there are previous reviews that have identified the use of MTSM as a risk factor for developing depression, other reviews have indicated their possible preventive effect.ObjectiveThe aim of this review was to synthesize the current evidence on the association between MTSM use and the development or prevention of depressive disorders in adolescents.MethodsAn umbrella review was conducted using information published up to June 2019 from PubMed/MEDLINE, PsycINFO, Web of Science, and The Cochrane Library. Systematic reviews focusing on the adolescent population (up to 20 years old) and depression and its potential relationship with MTSM use were included. Screening of titles, abstracts, and full texts was performed. After selecting the reviews and given the heterogeneity of the outcome variables and exposures, a narrative synthesis of the results was carried out.ResultsThe search retrieved 338 documents, from which 7 systematic reviews (3 meta-analyses) were selected for data extraction. There were 11-70 studies and 5582-46,015 participants included in the 7 reviews. All reviews included quantitative research, and 2 reviews also included qualitative studies. A statistically significant association between social media and developing depressive symptoms was reported in 2 reviews, while 5 reviews reported mixed results.ConclusionsExcessive social comparison and personal involvement when using MTSM could be associated with the development of depressive symptomatology. Nevertheless, MTSM might promote social support and even become a point of assistance for people with depression. Due to the mixed results, prospective research could be valuable for providing stronger evidence.
Model-Based Algorithms for Detecting Peripheral Artery Disease Using Administrative Data From an Electronic Health Record Data System: Algorithm Development Study
Authors: Weissler Elizabeth Hope , Lippmann Steven J , Smerek Michelle M , Ward Rachael A , Kansal Aman , Brock Adam , Sullivan Robert C , Long Chandler , Patel Manesh R , Greiner Melissa A , Hardy N Chantelle , Curtis Lesley H , Jones W Schuyler 
Published: July 2020

Background
Peripheral artery disease (PAD) affects 8 to 10 million Americans, who face significantly elevated risks of both mortality and major limb events such as amputation. Unfortunately, PAD is relatively underdiagnosed, undertreated, and underresearched, leading to wide variations in treatment patterns and outcomes. Efforts to improve PAD care and outcomes have been hampered by persistent difficulties identifying patients with PAD for clinical and investigatory purposes.

Objective
The aim of this study is to develop and validate a model-based algorithm to detect patients with peripheral artery disease (PAD) using data from an electronic health record (EHR) system.

Methods
An initial query of the EHR in a large health system identified all patients with PAD-related diagnosis codes for any encounter during the study period. Clinical adjudication of PAD diagnosis was performed by chart review on a random subgroup. A binary logistic regression to predict PAD was built and validated using a least absolute shrinkage and selection operator (LASSO) approach in the adjudicated patients. The algorithm was then applied to the nonsampled records to further evaluate its performance.

Results
The initial EHR data query using 406 diagnostic codes yielded 15,406 patients. Overall, 2500 patients were randomly selected for ground truth PAD status adjudication. In the end, 108 code flags remained after removing rarely- and never-used codes. We entered these code flags plus administrative encounter, imaging, procedure, and specialist flags into a LASSO model. The area under the curve for this model was 0.862.

Conclusions
The algorithm we constructed has two main advantages over other approaches to the identification of patients with PAD. First, it was derived from a broad population of patients with many different PAD manifestations and treatment pathways across a large health system. Second, our model does not rely on clinical notes and can be applied in situations in which only administrative billing data (eg, large administrative data sets) are available. A combination of diagnosis codes and administrative flags can accurately identify patients with PAD in large cohorts.
A Mobile Gaming Intervention for Persons on Pre-Exposure Prophylaxis: Protocol for Intervention Development and Randomized Controlled Trial
Authors: Whiteley Laura , Olsen Elizabeth , Mena Leandro , Haubrick Kayla , Craker Lacey , Hershkowitz Dylan , Brown Larry K 
Published: July 2020

BackgroundIn the United States, young minority men who have sex with men (MSM) are the most likely to become infected with HIV. Pre-exposure prophylaxis (PrEP) is an efficacious and promising prevention strategy. However, PrEP’s safety and effectiveness can be greatly compromised by suboptimal adherence to treatment. To maximize the positive impact of PrEP, it is necessary to combine its prescription with cost-effective behavioral interventions that promote adherence and decrease HIV risk behaviors. In this project, we developed a theoretically informed app/gaming intervention to engage young MSM in learning information, practicing behaviors, and improving motivation for HIV preventative behaviors and PrEP adherence.ObjectiveThe goal of this project was to develop and test a cutting-edge, engaging, and entertaining app/gaming intervention for improving adherence to PrEP and building HIV prevention knowledge, skills, and behavior.MethodsThis study was conducted in two phases. In the developmental phase, we conducted qualitative interviews with young MSM (n=20) to guide the development of the gaming intervention. In the randomized controlled trial, we tested the preliminary efficacy of the gaming intervention compared to a comparison condition among young MSM. Subjects were recruited from the University of Mississippi Medical Center HIV/STI testing clinics (n=60).ResultsInstitutional review board approval was received in February 2015. Research activities began in June 2015 and are still ongoing.ConclusionsThis app/gaming intervention aimed to improve PrEP adherence and HIV preventative behaviors in young MSM. Engaging young MSM in learning information, practicing behaviors, and improving motivation for increased adherence to PrEP has the potential to decrease HIV seroconversion. It is important to develop interventions that are enjoyable, engaging, and easily incorporated into clinical settings.Trial RegistrationClinicalTrials.gov RCT02611362; https://tinyurl.com/y65gkuwrInternational Registered Report Identifier (IRRID)DERR1-10.2196/18640
Decompensation in Critical Care: Early Prediction of Acute Heart Failure Onset
Authors: Essay Patrick , Balkan Baran , Subbian Vignesh 
Published: July 2020

Background
Heart failure is a leading cause of mortality and morbidity worldwide. Acute heart failure, broadly defined as rapid onset of new or worsening signs and symptoms of heart failure, often requires hospitalization and admission to the intensive care unit (ICU). This acute condition is highly heterogeneous and less well-understood as compared to chronic heart failure. The ICU, through detailed and continuously monitored patient data, provides an opportunity to retrospectively analyze decompensation and heart failure to evaluate physiological states and patient outcomes.

Objective
The goal of this study is to examine the prevalence of cardiovascular risk factors among those admitted to ICUs and to evaluate combinations of clinical features that are predictive of decompensation events, such as the onset of acute heart failure, using machine learning techniques. To accomplish this objective, we leveraged tele-ICU data from over 200 hospitals across the United States.

Methods
We evaluated the feasibility of predicting decompensation soon after ICU admission for 26,534 patients admitted without a history of heart failure with specific heart failure risk factors (ie, coronary artery disease, hypertension, and myocardial infarction) and 96,350 patients admitted without risk factors using remotely monitored laboratory, vital signs, and discrete physiological measurements. Multivariate logistic regression and random forest models were applied to predict decompensation and highlight important features from combinations of model inputs from dissimilar data.

Results
The most prevalent risk factor in our data set was hypertension, although most patients diagnosed with heart failure were admitted to the ICU without a risk factor. The highest heart failure prediction accuracy was 0.951, and the highest area under the receiver operating characteristic curve was 0.9503 with random forest and combined vital signs, laboratory values, and discrete physiological measurements. Random forest feature importance also highlighted combinations of several discrete physiological features and laboratory measures as most indicative of decompensation. Timeline analysis of aggregate vital signs revealed a point of diminishing returns where additional vital signs data did not continue to improve results.

Conclusions
Heart failure risk factors are common in tele-ICU data, although most patients that are diagnosed with heart failure later in an ICU stay presented without risk factors making a prediction of decompensation critical. Decompensation was predicted with reasonable accuracy using tele-ICU data, and optimal data extraction for time series vital signs data was identified near a 200-minute window size. Overall, results suggest combinations of laboratory measurements and vital signs are viable for early and continuous prediction of patient decompensation.
O HEROÍSMO DOS BRUTOS: REMINESCÊNCIAS DO GROTESCO E DO ROMÂNTICO EM FRANKENSTEIN E CARVÃO ANIMAL
Authors: Lima Diego Henrique de 
Published: July 2020

O presente artigo tem como objetivo refletir sobre a relação de influência entre a literatura de Mary Shelley e Ana Paula Maia. O que a obra da autora inglesa tem em comum com a autora brasileira em relação à elaboração de personagens anti-heróis e esteticamente grotescos. A tessitura dos protagonistas tanto de Frankenstein, de Shelley, quanto de Carvão Animal, de Maia, constroem um caso de influência atual dos modelos criados na era pré-vitoriana e na vitoriana. A partir dos conceitos de estranho (Umheiliche), de Freud, e do grotesco, por Bakhtin e Kayser, intencionamos discernir a rede de correspondências entre os protagonistas de Frankenstein e Carvão Animal.PALAVRAS-CHAVE: Anti-herói; Romantismo; Mary Shelley; Ana Paula Maia.
PENGARUH MODEL PEMBELAJARAN TALKING STICK BERBANTUAN LAGU DAERAH TERHADAP HASIL BELAJAR IPS
Authors: Trianti Lestari Ni Ketut , Kristiantari Mg. Rini , Ganing Ni Nyoman 
Published: July 2020

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar IPS kelompok siswa yang dibelajarkan dengan model pembelajaran Talking Stick berbantuan lagu daerah dan kelompok siswa yang dibelajarkan dengan pembelajaran konvensional pada siswa kelas V SD Gugus Lodtunduh Kecamatan Ubud Tahun Ajaran 2016/2017. Sampel penelitian diperoleh Kelas V SD Negeri 3 Lodtunduh sebagai kelompok eksperimen dan Kelas V SD Negeri 4 Lodtunduh sebagai kelompok kontrol. Data yang dikumpulkan menggunakan tes dan dianalisis menggunakan uji-t. Hasil Penelitian menggunakan uji hipotesis diperoleh thitung = 5,057, sedangkan ttabel = 2,00. Sehingga dapat dikatakan bahwa thitung = 5,057 > ttabel= 2,00, maka H0 ditolak dan Ha diterima. Nilai rata-rata hasil belajar IPS siswa pada kelas eksperimen yaitu = 77,08 dan pada kelas kontrol yaitu = 67,71. Dengan demikian, dapat disimpulkan bahwa model pembelajaran Talking Stick berbantuan lagu daerah berpengaruh terhadap hasil belajar IPS siswa kelas V SD Gugus Lodtunduh Kecamatan Ubud Tahun Ajaran 2016/2017.
PENGARUH MODEL PEMBELAJARAN ROLE PLAYING BERBASIS TAT TWAM ASI TERHADAP PENGUASAAN KOMPETENSI PENGETAHUAN IPS
Authors: Adnyana I Made Wira , Putra I Ketut Adnyana , Suadnyana I Nengah 
Published: July 2020

Penelitian ini bertujuan untuk mengetahui perbedaan yang signifikan penguasaan kompetensi pengetahuan IPS antara kelompok siswa yang dibelajarkan dengan model pembelajaran role playing berbasis tat twam asi dan kelompok siswa yang dibelajarkan dengan pembelajaran konvensional pada siswa kelas V SD Negeri Gugus Budi Utomo Tahun Ajaran 2016/2017. Sampel penelitian diperoleh Kelas V SD Negeri 14 Kesiman sebagai kelompok eksperimen dan Kelas V SD Negeri 6 Kesiman sebagai kelompok kontrol. Hasil analisis data diperoleh thitung Sebesar 4,634. Taraf signifikansi 5% dan dk=67 diperoleh batas penolakan hipotesis nol sebesar 2,00. Berarti thitung > ttabel yaitu 4,634 > 2,00, maka Ho ditolak dan Ha diterima. Rata-rata skor penguasaan kompetensi pengetahuan IPS kelompok eksperimen X̅ = 0,60 > X̅ = 0,41 siswa kelompok kontrol. Jadi dapat disimpulkan bahwa terdapat pengaruh model pembelajaran role playing berbasis tat twam asi terhadap kompetensi pengetahuan IPS siswa kelas V SD Negeri Gugus Budi Utomo Tahun Ajaran 2016/2017.
Keefektifan Model Pembelajaran Numbered Heads Together Berbantu Media Panelpa (Papan Flanel IPA) Terhadap Hasil Belajar
Authors: Wiji Hastuti Hikmah , Baedowi Sunan , Mushafanah Qoriati 
Published: July 2020

Tujuan dari penelitian ini adalah untuk mengetahui keefektifan model Numbered Heads Together berbantu media Panelpa (papan flanel IPA) terhadap hasil belajar siswa kelas V SDN 03 Sungapan Pemalang. Jenis desain yang digunakan dari pre-experimental design ini adalah one-group pretest-posttest design (satu kelompok pretes – postes). Populasi dalam penelitian ini adalah seluruh siswa kelas V di SD Negeri 03 Sungapan Pemalang. Adapun pengambilan sampel dalam penelitian ini yaitu dengan menggunakan sampling jenuh. Data dalam penelitian ini diperoleh melalui tes tertulis, wawancara, dan dokumentasi. Hasil penelitian menunjukan adanya peningkatan hasil belajar siswa yang dapat dilihat berdasarkan hasil pretest dan posttest yang sudah dilakukan. Rata-rata pretest yang diperoleh siswa sebesar 60,4 dengan nilai tertinggi 88 dan nilai terendah 32. Sedangkan nilai rata-rata posttest yang diperoleh sebesar 83,2 dengan nilai tertinggi 100 dan nilai terendah 56. Hal tersebut telah dibuktikan dalam pengujian hipotesis, yang menyatakan bahwa nilai thitung lebih besar dari pada nilai ttabel (5,433 > 1,729) yang artinya H0 ditolak dan Ha diterima. Hal ini berarti bahwa pembelajaran dengan menggunakan model Numbered Heads Together berbantu media Panelpa efektif terhadap hasil belajar siswa.
Pengaruh Model Pembelajaran Kooperatif Tipe Make A Match terhadap Motivasi dan Hasil Belajar Matematika
Authors: Anggraeni Ayu Anggita Anggita , Veryliana P , Fatkhu R Ibnu Fatkhu R 
Published: July 2020

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran kooperatif tipe make a match pada materi bangun datar kelas V SDN 1 Balun Banjarnegara dilihat pada motivasi dan hasil belajar siswa. Jenis penelitian ini adalah penelitian kuantitatif dalam bentuk Quaisi Experimental Design dengan desain Nonequivalent Control Group Design. Populasi penelitian adalah seluruh siswa kelas V SDN 1 Balun Banjarnegara tahun pelajaran 2018-2019 . Sampel yang diambil adalah siswa kelas V A berjumlah 22 siswa dan siswa kelas V B berjumlah 21 siswadengan menggunakan teknik Non Probability Sampling. Data dalam penelitian ini diperoleh melalui dokumentasi, observasi, angket, dan tes. Hasil analisis angket motivasi siswa menunjukan bahwa presentase kelompok eksperimen (90,91%) lebih besar dari kelompok kontrol (57,14%), serta berdasarkan hasil hitung uji t diketahui lebih besar dari (2,995>2,021). Kesimpulannya bahwa model pembelajaran Make A Match berpengaruh terhadap motivasibelajar siswa. Nilai kelompok eksperimen diketahui rata-rata 65,91 lebih besar dari kelompok kontrol 49,05, serta berdasarkan hasil uji t di ketahui lebih besar dari (6,502>2,01).
Toplesfer: Media Sederhana Untuk Mendukung Pembelajaran Demonstrasi Pada Pelajaran Geografi
Authors: Umam Qoidul , Sunaryo Sunaryo 
Published: July 2020

Sulitnya akses media pembelajaran geografi yang murah dan terjangkau sangat sulit didapatkan sehingga hal ini harus disiasati dengan baik. Padahal seyogyanya dalam pembelajaran geografi dibutuhkan alat-alat yang mendukung untuk praktikum dalam penjelasan materi. Adapun tujuan penelitian ini adalah (1) untuk mendeskripsikan langkah-langkah pembuaan media toplesfer, (2) untuk mendeskripsikan penggunaan media toplesfer dalam pembelajaran dengan metode demonstrasi pada materi atmosfer serta menganalisa dampak penggunaan toplesfer bagi siswa. Metode yang digunakan dalam penelitian ini ialah dengan pendekatan kualitatif. Data diperoleh melalui observasi di dalam kelas pada saat pembelajaran berlangsung. Hasil penelitian menunjukkan bahwa media toplesfer merupakan alat praktikum geografi yang sederhana dengan bahan bekas yang mudah dijangkau. Hal ini memberikan alternatif dalam pemaparan materi sehingga siswa antusias dan memberikan respon positif dengan adanya toplesfer tersebut. Toplesfer dapat menjelaskan materi tentang evaporasi, kondensasi, presipitasi, tekanan udara dan awan tornado. Selain itu, pada proses pembelajaran rasa ingin tahu siswa menjadi lebih baik mengingat ada sesuatu yang baru dalam mendemonstrasikan materi pelajaran. Kata kunci: geografi, pembelajaran dan toplesfer
Analisis Pengembangan Ekonomi Kreatif Kuliner Khas Suku Dayak Kalimantan Tengah
Authors: Alexandro Rinto , Uda Tonich , Pane Laba Lastaida 
Published: July 2020

Ekonomi kreatif di era digital saat ini semakin berkembang, selain menawarkan peluang, namun juga memunculkan persaingan, misalnya dalam dunia kuliner yang memberikan tantangan tersendiri bagi Kota Palangka Raya yaitu bagaimana mengangkat dan mengembangkan kuliner khas daerah di tengah maraknya kuliner modern. Tujuan penelitian ini adalah untuk menganalisis dan mengetahui pengembangan ekonomi kreatif di Kota Palangka Raya khususnya pada sektor kuliner oleh-oleh khas Suku Dayak Kalimantan Tengah. Jenis penelitian ini adalah penelitian kualitatif yang dianalisis menggunakan metode deskriptif. Teknik pengumpulan data yang dilakukan dalam penelitian yaitu dihimpun dari observasi, wawancara mendalam, studi literatur dan dokumentasi, kemudian dilakukan teknik analisis data yang dikembangkan oleh Miles, Huberman dan Saldana menggunakan empat alur kegiatan dalam analisis data yaitu, pengumpulan data, kondensasi data, penyajian data, serta penarikan kesimpulan. Hasil penelitian menemukan bahwa pengembangan ekonomi kreatif oleh-oleh kuliner khas Kalimantan Tengah di MEFs Food & Snacks berjalan dengan baik dan berpotensi unggul di tengah persaingan yang ketat terutama dengan kuliner modern. Selain itu, hal ini berimplikasi pada perilaku ekonomi produsen yaitu semakin termotivasi untuk mengeksplor makanan khas Kalimantan Tengah yang dapat di angkat dan diperkenalkan ke luar daerah.Kata kunci: Ekonomi kreatif, Kearifan Lokal, Kuliner Suku Dayak
Analisis Faktor-Faktor Penyebab Terjadinya Pengangguran dan Urbanisasi Pemuda di Desa Tamansari Kecamatan Karangmoncol Kabupaten Purbalingga Provinsi Jawa Tengah
Authors: Wijaya Placenta Abshar , Suprihanto John , Riyono Bagus 
Published: July 2020

Some of the problems that are frequently found in villages are unemployment and urbanization among rural youth. This study aimed to (1) Identify the factors that cause unemployment and urbanization among the youth in Tamansari Village, Karangmoncol Subdistrict, Purbalingga Regency, Central Java Province, (2) Analyze the causes of unemployment and urbanization among the youth in Tamansari Village, Karangmoncol Subdistrict, Purbalingga Regency, Central Java Province. This was a qualitative descriptive study. The informants in this study were the young people in Tamansari Village, and the Head of Tamansari Village. The data were collected through interview, observation, documentation, and online data search techniques. The analysis in this study was carried out using descriptive qualitative analysis and comparative analysis. The results of the study showed that (1) There are some factors that cause unemployment and urbanization among the youth in Tamansari Village, Karangmoncol Subdistrict, Purbalingga Regency, Central Java Province, (2) Several causes of unemployment and urbanization among the youth in Tamansari Village, Karangmoncol Subdistrict, Purbalingga Regency, Central Java Province were revealed.
The Importance of Initial Public Offering for Capital Market Development in Developing Countries
Authors: Pešterac Aleksandra 
Published: July 2020

Abstract
The first issue of shares is the key moment in the life cycle of any company that was not previously listed on a stock exchange. Considering the fact that transformation into a public open joint stock company brings along a number of advantages and challenges, it would be of great importance to possess knowledge about initial public offering (IPO) issuing activity, as well as stay updated with the number and value of globally realised IPOs. The aim of the paper is to use the comprehensive analysis of IPOs realisation process in order to point out the importance of going public, having in mind both the corporations and investors in the capital market, as well as the economy as a whole. In accordance with the set goal, the paper will present the effects of the realised IPO processes in the countries of Western Europe, China, Japan and the USA. When it comes to developing countries, the IPO of shares on a stock exchange is of special importance, since it contributes to the further development of capital market. Due to the particularity of the Serbian macroeconomic environment, the trends of privatisation process, the insufficient protection of investors, the high level of information asymmetry and the lack of corporate education, there have been no IPO processes realised on the Belgrade Stock Exchange over the past eight decades.
Effect of goose parvovirus and duck circovirus coinfection in ducks
Authors: Liu Jie , Yang Xiaoxia , Hao Xiaojing , Feng Yongsheng , Zhang Yuli , Cheng Ziqiang 
Published: July 2020

Abstract

Introduction
Coinfection of goose parvovirus (GPV) and duck circovirus (DuCV) occurs commonly in field cases of short beak and dwarfism syndrome (SBDS). However, whether there is synergism between the two viruses in replication and pathogenicity remains undetermined.

Material and Methods
We established a coinfection model of GPV and DuCV in Cherry Valley ducks. Tissue samples were examined histopathologically. The viral loads in tissues were detected by qPCR, and the distribution of the virus in tissues was detected by immunohistochemistry (IHC).

Results
Coinfection of GPV and DuCV significantly inhibited growth and development of ducks, and caused atrophy and pallor of the immune organs and necrosis of the liver. GPV and DuCV synergistically amplified pathogenicity in coinfected ducks. In the early stage of infection, viral loads of both pathogens in coinfected ducks were significantly lower than those in monoinfected ducks (P < 0.05). With the development of the infection process, GPV and DuCV loads in coinfected ducks were significantly higher than those in monoinfected ducks (P < 0.05). Extended viral distribution in the liver, kidney, duodenum, spleen, and bursa of Fabricius was consistent with the viral load increases in GPV and DuCV coinfected ducks.

Conclusion
These results indicate that GPV and DuCV synergistically potentiate their replication and pathogenicity in coinfected ducks.