bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Ipaac Evaluation Tool: how to select Quality Indicators for Comprehensive Cancer Care Networks
Authors: Cocchiara R A , Lia L , Dorelli B , Mannocci A , Follmann M , Griesshammer E , Wesselmann S , De Angelis R , Federici A , La Torre G 
Published: October 2020

Abstract

Background
The Comprehensive Cancer Care Networks (CCCNs) represent innovative approaches for the management of cancer patients consisting of multiple cooperating health units with specific expertise in the different steps of care. Quality Indicators (QIs) constitute valid and reliable tools that allow to measure the quality of care among similar structures belonging to different health systems. Objective of this project was to develop a standardized tool in order to define a multi-step process for the selection of QIs for the evaluation of CCCNs.

Methods
Under the coordination of the Innovative Partnership for Action Against Cancer (IPAAC) joint action, our research team performed a systematic review of the scientific literature to identify the reported methodology for the selection of QIs applicable for the CCCNs' setting. An additional search of national and international Quality Assurance organizations was performed to detect any missing information.

Results
The IET (Ipaac Evaluation Tool) for QIs was developed: a methodological tool describing an 8-step process that leads to the selection of QIs feasible for the CCCN setting. The tool was implemented accordingly with the reporting standards for guideline-based performance measures of the Guideline International Network (GIN). A pilot testing of the tool was performed in order to identify its strengths and weaknesses.

Conclusions
The IET for QIs represents an innovative methodological instrument to select valid and reliable indicators for the assessment of the quality of care within the CCCN settings.

Key messages
The Quality Indicators represent valid and reliable tools to measure and compare the quality of care delivered to cancer patients in Comprehensive Cancer Care Networks. The development of the Ipaac Evaluation Tool leads to a standardized assessment of the quality of care provided for cancer patients within the CCCN setting.
Profiling biopsychosocial health of cancer-diagnosed elderly in Italy by Passi d’Argento, 2016-2017
Authors: Contoli B , Minardi V , Possenti V , Carrozzi G , Cristofori M , D'Argenzio A , De Luca A M C , Ramigni M , Trinito M O , Masocco M 
Published: October 2020

Abstract

Background
PASSI d'Argento (PdA) is an Italian population-based surveillance system, coordinated by the Istituto Superiore di Sanità (ISS) and carried out by the Local Health Units (LHUs). PdA monitors wide-ranged health related-behaviours in the elderly (65+) living in Italy as per the three pillars of the “Active Healthy Ageing” framework: Health, Participation, Security.

Methods
The PdA sample is randomly selected from the LHU lists, stratified by sex and age. 22,811 records have been collected in 2016-2017 on a representative sample of residents aged over65, not being hospitalised, in long-term care, in a nursing home or prison.

Results
3,019 respondents resulted cancer-diagnosed elderly (CDE) reporting cancer diagnosis or confirmation, leukaemia and lymphomas included (annual average prevalence of 12.8%, Confidence Intervals 95%: 12.1-13.4%; one million and 729 thousand people). CDE refer: poorer health conditions (22%) than Chronic Elderly Patients (CEP; 18%) and Healthy Elderly (HE; 5%), sight impairment (12%), hearing loss (15%) and chewing problems (14%). CDE (10%) and CEP (11%) are more prone to fall than HE do (6%). Disability accounts for 21% in CDE and CEP vs. 12% in HE. A multivariate analysis confirms a compromised psychophysical health profile in CDE vs. HE, and vs. CEP. CDE behave still unhealthily, are insufficiently advised by health professionals, do not comply with the seasonal flu vaccination [Health]. CDE face increased risk for isolation or cognitive decline: they experience lower social connectedness (17%) than CEP (20%) and HE (28%) [Participation], and perceive higher neighbourhood insecurity (19%) than how CEP (17%) and HE (13%) do [Security].

Conclusions
PdA data on the poor biopsychosocial health profile of CDE highlight to what extent healthy behaviours and prevention can ameliorate their quality of life PdA calls for global action strategies in Italy, which aim at taking complete charge of CDE and also CEP.

Key messages
In Italy, elderly cancer survivors show poor biopsychosocial health profile and overall quality of life. By modifying behaviours, elderly suffering from any cancer or chronic disease can age healthily.
Palliative care delivery according to age among metastatic breast cancer patients. ESME-MBC cohort
Authors: Frasca M , Courtinard C , Bouleuc C , Levy C , Mouret-Reynier M A , Bachelot T , Goncalves A , Perotin V , Eymard J C , Mathoulin-Pelissier S 
Published: October 2020

Abstract

Background
Metastatic breast cancer (MBC) may require inpatient palliative care (IPC) but literature suggests age-related disparities in palliative care delivery. This study, based on real-world data, aimed to assess the cumulative incidence function (CIF) of IPC delivery and if age is an independent factor, taking into account the competing risk of death.

Methods
The national multicenter ESME (Epidemio-Strategy-Medical-Economical)-MBC cohort includes consecutive MBC patients treated in the 18 French Comprehensive Cancer Centers. IPC identification used ICD-10 palliative care coding. Main analysis first estimated pseudo values of 2-year and 8-year CIF of IPC. Linear regression models estimated the mean changes of pseudo-values (2 models: 2-year and 8-year CIF of IPC).

Results
Our analysis included 12375 patients, 5093 (41.2%) of whom were aged 65 or over. The median follow-up was 41.5 months (95% CI, 40.5-42.5). The CIF of IPC was 10.3% (95% CI, 10.2-10.4) and 24.8% (95% CI, 24.7-24.8) at two and eight years, respectively. At two years, among triple-negative patients, young patients (&lt;65 yo) had a higher CIF of IPC than older patients after adjusting for cancer characteristics, centre, and period (65+/&lt;65: β=-0.05; 95% CI, -0.08 to -0.01). Among other tumour subtypes, older patients received short-term IPC more frequently than young patients (65+/&lt;65: β = 0.02; 95% CI, 0.01 to 0.03). At eight years, outside large centres, IPC was delivered less frequently to older patients adjusted to cancer characteristics and period (65+/&lt;65: β=-0.03; 95% CI, -0.06 to -0.01).

Conclusions
We found a relatively low CIF of IPC and that age influenced IPC delivery. Young triple negative and older non-triple negative patients needed more short-term IPC. Older patients diagnosed outside large centres received less long-term IPC. These findings highlight the need for a wider implementation of IPC facilities and for more age-specific interventions.

Key messages
Our study highlighted particular challenge for older MBC patients diagnosed outside large French Comprehensive Cancer Centers. By identifying age at MBC diagnosis as a factor of IPC delivery, this report supports a wider implementation of IPC facilities and more age-specific interventions.
Cultural dance significantly improves hypertension management
Authors: Look M , de Silva M , Ahn H J , Austin Seabury A , Vegas J K , Kim C , Dillard A , Gonsalves J , Haumea S , Kaholokula J K 
Published: October 2020

Abstract
Hypertension (HT), uncontrolled blood pressure (&gt;140/90 mmHg), is the leading preventable cause of premature death globally and a major risk factor for coronary heart disease, stroke, and other conditions. European and African regions have the highest prevalence rates at about 40% of adults. The U.S. has comparable rates and disturbing disparities in non-White minority groups. Native Hawaiians (NH), an indigenous U.S. population, are 70% more likely to have HT; 4 times more likely to have coronary heart disease or stroke than Whites. Hula, the cultural dance of NH, offers promise of a culturally responsive strategy for HT control.
We conducted a randomized clinical trial with a waitlist control to test the impact of a hula-based cultural dance intervention (CDI) on systolic blood pressure (SBP) in 263 NH with HT. All participants received HT education (e.g. diet, exercise, medication) during 3 1-hr sessions over 2 weeks, then randomly assigned to CDI (n = 131) or waitlist control (WC; n = 132). The CDI received 6 months of hula (2 1-hr sessions/week x 3 months, then 1 lesson/mth x 3 months with self-directed practice), with group activities to reinforce HT education. WC only received the initial HT education, then offered hula after the study. Assessments were done at 0-, 3- and 6-month, with 12-month for CDI only.
Baseline characteristics were balanced between groups, except for weight. Adjusting for weight and baseline SBP in intent-to-treat analysis, CDI achieved significant reductions (p &lt; .05) in SBP (-15.3 mmHg; SE = 1.6) compared to WC (-11.8 mmHg, SE = 1.7). From 6 to 12 months, CDI maintained their SBP (mean change: 1.47 mmHg, SE = 1.26; p = .16) improvements at 12 months. CDI were more likely to achieve SBP reduction ≥ 10 mmHg than WC, 60% vs 48% (p = .03), respectively.
A CDI based on the NH cultural dance significantly improved HTN management in NH with uncontrolled SBP. Improvements were comparable to the best proven non-medication treatment of HT.

Key messages
Improving elevated blood pressure control with at-risk populations can be effectively and innovatively achieved by utilizing culturally responsive strategies, such as cultural dance interventions. Leveraging and aligning community strengths and health objectives leads to innovation and empowerment.
The Requirements of Developing Countries' Health Systems Facing with COVID-19: A Case Study of Iran
Authors: Ghanbarzadegan A , Bastani P , Emadi F , Mohammadpour M , Pourmohammadi K , Javanmardi S 
Published: October 2020

Abstract

Background
Epidemic COVID-19 in 2020 was one of the crises that confronted the Islamic Republic of Iran's health system as a developing low-income country with many challenges. The purpose of this study is to explain the requirements of similar health systems in facing epidemics such as COVID-19 as well as sharing experiences of Iran.

Methods
The present study was a qualitative study using content analysis of the Iranian Ministry of Health website (behdasht.gov.ir) during the official onset of COVID-19 in Iran (February 20) to March 7, 2020. To Integrate data, interviews with experts were used. In this regard, 4 national health policymakers and 5 provincial health managers were interviewed. After implementation using 8-step content analysis method, data were analyzed using MAXQDA software by research team members who had no conflict of interest.

Results
The findings show that the disease began on February 20, 2020, with two cases of death from COVID-19 in Qom province in central Iran and within two weeks it has widely affected 31 provinces, with 4747 approved cases and 124 deaths. According to the results, the Islamic Republic of Iran's health system faced five major challenges to confronting with COVID-19: 1- Medical consumables supply 2- Hospital beds allocation and intensive care units (ICU) equipment 3-The lack of a comprehensive COVID-19 protocol in the country 4- the lack of a single command authority to deal with the crisis 5- Insufficient public health literacy and information as a result of social anxiety.

Conclusions
Experiences of this case indicate that health systems require policy action to prevent and control diseases rather than other implementations. In this regard, training should be given to children and adolescents, at-risk persons and health system staff. In addition, to confront with COVID-19, an integrated policy implementation team should be established in collaboration with the health sector and other relevant bodies.

Key messages
It seems obvious that policy implementation requires to prepare the country for future contingencies. A comprehensive National Prevention Protocol needs to be developed.
Effect of COVID-19 outbreak on emergency department attendances in an Italian academic hospital
Authors: Poletto M , Perri G , Malacarne F , Bianchet B , Doimo A , Deroma L , Lattuada L 
Published: October 2020

Abstract

Background
Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was discovered during the 2019 outbreak in Mainland China and the first cases were reported in Italy on February 21, 2020. This study evaluates the emergency department (ED) attendances of an academic hospital in northern Italy before and after media reported the news of the first infected patients in Italy.

Methods
Adult attendances in ED in February 2020 were analysed dividing the period into 4 weeks (days 1-7, 8-14, 15-21, 22-28) compared with the same periods in 2019. The visits were analysed separately according to the Italian colour code of triage: white (non-critical), green (low-critical), yellow (medium critical), red (life-threatening). The mean weekly number of attendances was compared with t-test.

Results
February 2020 total ED attendances compared with February 2019 were 4865 vs 5029 (-3.3%), of which white codes were 834 vs 762 (+9.4%), green 2450 vs 2580 (-5.0%), yellow 1427 vs 1536 (-7.1%), red 154 vs 151 (+2.0%). February 2020 weekly mean ED attendances compared with February 2019 had statistically significant difference only in the fourth week (days 22-28) for green codes (75 vs 92, p = 0.007) and yellow codes (41 vs 52, p = 0.047), not for white (27 vs 26, p = 0.760) and red codes (5 vs 5, p = 0.817). The first three weeks of February 2020 compared with 2019 showed no statistically significant difference in weekly mean ED attendances.

Conclusions
There was a significant reduction of green and yellow codes attendances at ED in the fourth week of February 2020, corresponding to the initial phase of Italian COVID-19 outbreak. The fear of contracting SARS-CoV-2 by attending the ED probably acted as a significant deterrent in visits, especially for low and medium critical patients. Additional data are required to better understand the phenomenon, including the behaviour of non-critical attendances.

Key messages
A reduction of green and yellow codes attendances was reported during initial phase of COVID-19 outbreak in an Italian academic hospital. Fear of contracting COVID-19 infection in a hospital setting could impact on emergency department attendances.
Beyond COVID-19: a cross-sectional study in Italy exploring the Covid Collateral Impacts
Authors: Gualano M R , Corradi A , Voglino G , Bert F , Siliquini R 
Published: October 2020

Abstract

Background
The COVID-19 pandemic is a calamity affecting many aspects. In particular healthcare services (HCS) are facing a great stress-test worldwide. The present work aims to explore what were health needs, beyond COVID, not covered among Italian citizens, due to fear, lockdown measures and overload of HCS, also in order to understand if there are specific subgroups of populations that will need urgent access to health services in the next future.

Methods
COCOS (COvid COllateral impactS) is a cross-sectional study performed during the Italian lockdown between April and May 2020. A forty-nine items online questionnaire was filled by the respondents. Participation was voluntary and without compensation. Informed consents were obtained. Descriptive, univariable and multivariable (logistic regression models) analyses were performed: results are expressed in ORs.

Results
Totally, 1,515 questionnaires were collected. Median age was 42 years, 65.6% were females. Around 22% declared to suffer from chronic diseases. Interestingly, 32.4% of the sample faced a delay of a scheduled Medical Service (MS) by provider decision, while 25.6% reported that this issue hit a family member. More than 13% refused to access scheduled MS for the fear of contagion, and the 6.5% avoided HCS even if having an acute onset issue: this behavior was associated with scarce trust in physicians (AdjOR 0.75); alarmingly, 1.5% avoided Emergency Department when in need and 5% of the sample took medications without consulting any physician: patients suffering from chronic conditions resulted to be more prone to self-medication (AdjOR: 2.16; 95% C.I.: 1.16-4.02).

Conclusions
COVID-19 immediate effects are just the tip of the iceberg. Large groups of population suffered delays and interruptions of medical services, and the most vulnerable were the most affected. To estimate the effects of the pandemic on non-COVID-19 patients is required, leading to aimed efforts, to reduce the backlog that HCS incurred in.

Key messages
COVID-19 biggest toll on public health is still to come if not prevented, due to temporary but widespread suspensions of scheduled medical services and the avoidance of these for fear of contagion. The most in need are the most vulnerable: older patients and those with chronic conditions are the most affected by suspension of medical services and will potentially pay the greatest cost.
Exposing the tactics of alcohol companies
Authors: Moore AM M 
Published: October 2020

Abstract

Background
The alcohol industry has taken a page from the tobacco industry play book in an attempt to resist regulation through delay, self-regulation and effective lobbying. The global alcohol industry is constantly seeking to increase sales of harmful products through widespread marketing, the targeting of young people, and resisting regulatory action.

Methods
An assessment of the number of lobbyists engaged in one form of another to influence members of Parliament in Australia is being conducted to provide an insight into the attempts to influence alcohol policy. This follows a scan of the lobbyists' register by Daube et al in 2018 that found the while the tobacco industry had 20 direct lobbyists and 14 indirect, the junk food industry 33 direct and 13 indirect, the most dominant was the alcohol industry with 43 direct and 23 indirect. A careful re-examination of the register in 2020 is expected to reveal an increase in these numbers. There will also be an examination of the State and Territory registers in an attempt to understand the overall numbers of people specifically attempting to influence governments.

Discussion
This particular examination is focussed on the Australian Parliament/s. However, the message will be similar world-wide. Companies such as Diageo have a significant share of the world market with net sales, for example, being 25% of scotch, 16% of beer and 11% of vodka. Their “Drinkiq” website claims “Diageo is committed to preventing and reducing alcohol abuse around the world”. However, other business websites illustrate that their prime objective is to sell more alcohol.

Presentation
The presentation will focus on the importance of countering the efforts of industry in increasing availability of alcohol. It will also provide a series of steps that public health advocates can take in order to persuade governments of the importance of protecting community health through appropriate regulation of the marketing and sales of alcohol.

Key messages
The alcohol industry seeks to increase sales while arguing it is protecting health. Public health advocates do have the tools to counter approaches by alcohol companies.
Changes in industry interference in policy in the United Kingdom 2017-2020
Authors: Chamberlain P , Gilmore A , Silver K , Zatoński M , Laurence L , Alebshehy R 
Published: October 2020

Abstract

Background
The Tobacco Industry Interference (TII) Index evaluates the implementation of FCTC Article 5.3. The first edition of the Global TII Index was published in 2019, included 33 countries, and covered the years 2017-2018. A second edition, covering 2018-2019, is scheduled to be published in October 2020. This paper reports on findings of the Index for the UK, the changes observed between 2017 and 2020, and the resulting policy recommendations.

Methods
The UK Index was based on a questionnaire covering different forms of tobacco industry interference. Lower scores indicate better compliance with Article 5.3. In order to complete the questionnaire, an expert consultation was conducted with UK's leading tobacco control specialists. This was supplemented by a scoping review of academic literature, media websites, government websites, and the Tobacco Tactics resource.

Results
In the 2019 Index the UK has achieved the lowest score among 33 countries surveyed. Strengths of the UK system included the exclusion of TI from government bodies that set public health policy and from FCTC COP delegations; the obligation of the government to publish information on all meetings with TI; and guidelines stipulating that its diplomats must not engage on behalf of TI. Nevertheless, weaknesses were also identified; including only partial implementation of the above obligations, the absence of an effective lobbying register, and the ongoing involvement of parliamentary consultative bodies, individual politicians and political parties with TI and affiliated organisations.

Discussion
The change of government in the UK in 2019, the shifting policy framework resulting from Brexit, and the increasing use by the tobacco industry of third parties to access policymakers, bring new challenges to the maintenance of robust Article 5.3 compliance. The presentation will analyse how this has affected the change in the UK's performance between the 2019 and the 2020 Tobacco Industry Interference Index.

Key messages
The need to strengthen transparency regulations for policymakers. A need for continued monitoring against an agreed framework in the light of very fluid political developments.