bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peculiarities of Spondylitis in the Patients Undergoing Program Hemodialysis (Case Report)
Authors: Mushkin M. A. , Dulaev A. K. , Tsed A. N. 
Published: March 2020

Relevance. The surgical treatment of spinal diseases and injuries in the patients on hemodialysis is one of the most complicated problems of the spine surgery, since such a surgery is associated with an increased risk of infectious complications and perioperative mortality. The case description. A 59-year-old female came to the clinic complaining back pain. Th8-9 vertebrae spondylitis complicated by an epidural and paravertebral abscess with pertinent neurological disorders and bilateral pneumonia were diagnosed. The patient had been on hemodialysis for 18 years due to the end-stage chronic kidney disease complicated by uremic osteodystrophy. The surgical debridement and stabilization of the spine were performed in one stage posterior approach using a titanium mesh implant in combination with autologous bone and posterior instrumentation. A regression of neurological disorders and the pain syndrome relief were achieved. In the late postoperative period, the instability of the posterior fixation developed twice, requiring restabilization. Within the following 3.5 years after the operation, the pain syndrome had not returned. Conclusion. The presence of equipment for hemodialysis and a multidisciplinary approach allow to achieve the positive results in the surgical treatment of inflammatory diseases of the spine in the patients with endstage chronic kidney disease.
Preventive Behaviors Conveyed on YouTube to Mitigate Transmission of COVID-19: Cross-Sectional Study
Authors: Basch Corey H , Hillyer Grace C , Meleo-Erwin Zoe C , Jaime Christie , Mohlman Jan , Basch Charles E 
Published: March 2020

Background
Accurate information and guidance about personal behaviors that can reduce exposure to severe acute respiratory syndrome coronavirus 2 are among the most important elements in mitigating the spread of coronavirus disease 2019 (COVID-19). With over 2 billion users, YouTube is a media channel that millions turn to when seeking information.

Objective
At the time of this study, there were no published studies investigating the content of YouTube videos related to COVID-19. This study aims to address this gap in the current knowledge.

Methods
The 100 most widely viewed YouTube videos uploaded throughout the month of January 2020 were reviewed and the content covered was described. Collectively, these videos were viewed over 125 million times.

Results
Fewer than one-third of the videos covered any of the seven key prevention behaviors listed on the US Centers for Disease Control and Prevention website.

Conclusions
These results represent an important missed opportunity for disease prevention.
El uso de las TIC y la lectura en la educación pública superior mexicana
Authors: Robles-Francia Víctor Hugo , De la Cruz-Caballero Adriana Mariela , Terrones Cordero Aníbal 
Published: March 2020

El presente trabajo analiza los problemas que presentan los universitarios en el uso de internet, el empleo de las tecnologías de información y comunicación (TIC) y el manejo de la lectura que manifiestan los estudiantes de educación pública superior. La población se integró por 3 106 estudiantes de universidades, 534 de escuelas normales, 576 de tecnológicos descentralizados y 330 de tecnológicos federales. Se utilizó el enfoque de investigación cuantitativo, realizándose una estadística descriptiva y un análisis de varianza ANOVA para determinar las diferencias en la utilización de tecnologías de información y comunicación en la lectura entre los diversos grupos de la población. Se encontró que existen diferencias significativas en el manejo de las TIC en la población analizada, puesto que los estudiantes tienen limitaciones en la lectura impresa y digital.
Устойчивое развитие в повестке архитектурного образования
Authors: Esaulov Georgy , Blagovidova Natalia , Tabunshchikov Yuri 
Published: March 2020

Область архитектуры и строительства ввиду большого вли­яния на окружающую среду является объектом регулирования посредством экологических доктрин. Однако в области про­фессионального и высшего архитектурного и строительного образования до настоящего времени не внедрена комплексная программа экологического образования. Ещё больше вопросов вызывает область градостроительного образования.
Ориентация деятельности на стратегию устойчивого развития заставляет архитектора и градостроителя искать адекватные и эффективные ответы на вызовы современности, опираясь на принципы этой стратегии.
В 2013 году в МАРХИ была разработана и в 2014-ом утверж­дена Концепция экологического образования. Предпосылки к её внедрению заложены в самой профессии архитектора и градостроителя, осуществляющих преобразование природ­ного ландшафта в антропогенный. Цель Концепции, с одной стороны, обеспечить непрерывность процесса формирования экологического мышления на всех этапах учебного процесса, с другой стороны, она позволяет задействовать в архитектур­ном проектировании инновационные технологии в области экологического строительства, разработанные специалистами инженерных кафедр.
Сущность интегрированного архитектурного образования в овладении способностью разрабатывать и реализовывать со­циально-философскую идею устойчивой среды обитания для конкретных условий региона, города на основе современных научных и технических достижений в области градостроитель­ства, архитектуры, экологической безопасности, конструкций, строительной физики и строительных материалов.
В основе этого подхода, названного «Интегрированное архитектурное образование», ориентированные на Стратегию устойчивого развития:

разработанная многоуровневая система интегрирован­ного устойчивого образования;
проектирование объектов как устойчивых архитектурно­инженерных умных систем;
рейтинговая система оценки здания на протяжении всего жизненного цикла - от проектирования до различных стадий эксплуатации.
Методология, методика, опыт работ по сохранению и приспособлению для современного использования парка усадьбы Михалково. Часть 1
Authors: Belyaeva Elena , Markina Irina , Moginov Boris 
Published: March 2020

На примере работ по сохранению объекта культурного на­следия (ОКН) регионального значения «Усадьба Михалково» в Москве рассмотрены методология и методика проектирова­ния парковой реставрации и задачи их совершенствования.
В 1784-1788 годах в Михалкове в стиле «псевдоготики» был построен архитектурный ансамбль парадного двора (архитектор В.И. Баженов) и устроен обширный пейзажный парк, куда вошли уже существовавшие в ту пору регулярный парк с копаными прудами и Головинские пруды.
Площадь ОКН «Усадьба Михалково» более 50 га. «Ядро усадьбы», включающее ансамбль парадного двора с регулярным парком - ОКН федерального значения, имеет площадь около 8 га.
Анализ архивных материалов и натурные обследования показали, что архитектурно-пространственная и ландшафтная организация изучаемого произведения СПИ соответствуют основным принципам создания русских пейзажных парков этого периода, особенно парков, характерных для творчества В.И. Баженова и его последователей.
На примере ОКН «Усадьба Михалково» показано, как про­счёты в оценке композиционных «особенностей» пейзажных парков, их сохранности, отсутствие в «предмете охраны» цен­ных элементов ландшафта могут негативно влиять на резуль­таты парковой реставрации. Для Михалково рекомендовано углублённое изучение композиционных особенностей пей­зажного парка, доработка «предмета охраны», исправление недостатков недавно выполненной парковой реставрации. Изучение опыта выполненных работ по реставрации и при­способлению к современному использованию имеет значение как для будущих реставраций рассматриваемого парка, так и для других исторических парков.
PENGARUH PENANAMAN MODAL DALAM NEGERI (PMDN) DAN PENANAMAN MODAL ASING (PMA) TERHADAP PRODUK DOMESTIK REGIONAL BRUTO (PDRB) SUMATERA UTARA TAHUN 2000-2018
Authors: Ruslan Dede , Hastuti Pebri , Irawan Dedi 
Published: March 2020

This research is titled foreign investment (PMA) and domestic investment (PMDN) on gross regional domestic product (GRDP) in North Sumatra. The purpose of this study was to analyze the effect of PMA and PMDN on GRDP. The method used in this research is a quantitative method that uses mathematical models to present facts or describe statistics to show the relationship between variables namely capital development and domestic investment of regional domestic products in North Sumatra. The results of data processing showed that PMA and PMDN variables in districts / cities in North Sumatra did not have a positive and significant effect on GRDP variables. Meanwhile, procedurally, PMA variable does not have a significant effect on GRDP while PMDN has a positive and significant effect on GRDP. Kata Kunci : Foreign Capital, Domestic Capital, Transition
Evaluation of dose-response effects of short-term oral prednisone administration on clinicopathologic and hemodynamic variables in healthy dogs
Authors: Tinklenberg Rebecca L. , Murphy Shane D. , Mochel Jonathan P. , Seo Yeon-Jung , Mahaffey Alyssa L. , Yan Yuqi , Ward Jessica L. 
Published: March 2020

Abstract

OBJECTIVE
To determine whether a dose-response relationship exists between short-term oral prednisone administration and common clinicopathologic variables, cardiovascular biomarkers, and systolic arterial blood pressure (SAP) in healthy dogs.

ANIMALS
8 healthy Beagles.

PROCEDURES
Dogs underwent five 5-day experiments (no prednisone treatment [control condition] and prednisone administration at 0.5, 1, 2, and 4 mg/kg, PO, q 24 h), with a 9-day washout period between protocols. Analyses performed before and after treatments included a CBC, serum biochemical analysis, and determination of SAP, fractional excretion of electrolytes, urine protein-to-creatinine ratio, glomerular filtration rate (GFR), serum N-terminal pro B–type natriuretic peptide (NT-proBNP) and plasma cortisol concentrations, and plasma renin activity. Linear mixed-effects modeling was used to compare changes in variables from baseline (day 1 for the same experiment) among treatment conditions.

RESULTS
Changes in serum glucose concentration and GFR were significantly greater after administration of prednisone at 4 mg/kg than for the control condition. Fractional excretion of sodium was decreased from baseline when dogs received 0.5, 1, or 4 mg of prednisone/kg, compared with results for the control condition. Several expected changes in clinicopathologic values were observed after prednisone administration at any dose. Changes in serum NT-proBNP concentration, plasma renin activity, and SAP did not differ from changes for the control condition at any prednisone dose.

CONCLUSIONS AND CLINICAL RELEVANCE
Oral prednisone administration did not affect SAP, NT-proBNP concentration, or measures of renin-angiotensin-aldosterone system activation in healthy laboratory-housed dogs but was associated with relative increases in GFR and serum glucose concentration.
Finite-time active disturbance rejection control for marine diesel engine
Authors: Wang Yuanqing , Zhang Guichen , Shi Zhubing , Wang Qi , Su Juan , Qiao Hongyu 
Published: March 2020

Abstract
In order to handle the non-linear system and the complex disturbance in marine engines, a finite-time convergence active disturbance rejection control (ADRC) technique is developed for the control of engine speed. First, a model for the relationship between engine speed and fuel injection is established on the basis of the mean value engine model. Then, to deal with the load disturbances and model parameter perturbation of the diesel engine, this paper designs an ADRC approach to achieve finite-time stability. Finally, simulation experiments show that the proposed method has better control effect and stronger disturbance rejection ability in comparison with the standard linear ADRC.
Antecedents of loyalty intentions among young adult tourists: a survey
Authors: Wąsowicz-Zaborek Elżbieta 
Published: March 2020

Abstract
The purpose of this paper was to examine the antecedents of young adult tourists’ loyalty intentions. The study is concerned with the overall loyalty tendencies of individuals, comprising the two dimensions of revisit intentions (RVIs) and recommendation intentions (RIs), and thus does not explore their loyalty to a specific destination (as in most previous studies). The research uses an Internet questionnaire with a total sample of 305 university students recruited from two Polish universities. Statistical analysis with the partial least squares structural equation modeling method indicates that destination RI is mainly driven by social bonding, while RVI is influenced positively by risk and uncertainty avoidance and negatively by novelty and variety seeking. In addition, income is found to be a significant moderator in the relationship between risk and uncertainty perception and RIs, such that a transition from very low to very high incomes tends to reverse the focal relationship from positive to negative. In addition, the research demonstrates that there is no significant difference between male and female young tourist’s loyalty intention. Implications for tourism entrepreneurs and destinations are suggested in the concluding section of the article.
The Earning Losses of Smokers
Authors: Bhai Moiz 
Published: March 2020

Abstract
Using within-family variation from twins and siblings, I find that smokers earn approximately 16% less than nonsmokers. Possible explanations for this earning difference are addiction-related productivity declines and earning reductions from higher health insurance costs. To investigate further, I use variation in the provision of employer-supplied health insurance (ESHI) to examine the mechanism of whether the addiction or insurance component has a larger influence on earnings. While I generally observe a larger earning penalty for smokers with ESHI than smokers without ESHI, the earning difference is statistically indistinguishable from zero.
A Practical Statistical Approach to the Reconstruction Problem Using a Single Slice Rebinning Method
Authors: Cierniak Robert , Pluta Piotr , Kaźmierczak Andrzej 
Published: March 2020

Abstract
The paper presented here describes a new practical approach to the reconstruction problem applied to 3D spiral x-ray tomography. The concept we propose is based on a continuous-to-continuous data model, and the reconstruction problem is formulated as a shift invariant system. This original reconstruction method is formulated taking into consideration the statistical properties of signals obtained by the 3D geometry of a CT scanner. It belongs to the class of nutating reconstruction methods and is based on the advanced single slice rebinning (ASSR) methodology. The concept shown here significantly improves the quality of the images obtained after reconstruction and decreases the complexity of the reconstruction problem in comparison with other approaches. Computer simulations have been performed, which prove that the reconstruction algorithm described here does indeed significantly outperforms conventional analytical methods in the quality of the images obtained.
Nanocharacterization of metallic thin films deposited on different substrates
Authors: Merie Violeta V. , Burnete Nicolae V. , Bîrleanu Corina , Pustan Marius 
Published: March 2020

Abstract
The purpose of this study was to determine the influence of different substrates (C45 steel, polycarbonate, glass) on the topography as well as tribological and mechanical properties (nanohardness, modulus of elasticity and friction force) of aluminum, gold and silver thin films. The 3D image analysis showed a strong influence of the substrate material on the topography of the studied thin films with no certain variation rule. Using the Oliver and Pharr method for determining nanohardness it was observed that, the smallest values were obtained for the thin films deposited on plastic substrate, followed by glass and C45 steel, regardless of the deposited material. The determination of the modulus of elasticity was done using the Hertzian method. The obtained results showed that the highest values of this parameter were obtained for the films deposited on plastic substrate, while the lowest values depended on both the deposited material and substrate. Friction force analysis for aluminum and gold showed a significant impact of the substrate material, with more constant values for gold. As a consequence, one must pay a particular attention when choosing the material for the substrate on which the thin films are deposited.
Geological Reconciliation Study: Estimated Remaining Overburden Material and Reserve at Sibanyis Quarry, Kuching, Sarawak
Authors: Cheng Jong E , Roslee Rodeano 
Published: March 2020

Abstract
This study presents the estimated remaining quantity of overburden material (topsoil, completely to highly weathered rock) and remaining geological reserve at Sibanyis Quarry, Kuching after the quarry has been operated for years. Desktop study including literature search was carried out prior field investigation. Three boreholes together with latest topographical and detail survey was conducted to obtain the latest data at Sibanyis Quarry, Kuching. Based on this Geological Reconciliation Study, the estimated total remaining geological rock reserve is 40,022,767 metric tons, and the weathered rock and top soil are 2,159,688 BCM and 1,247,697 BCM respectively. The assumptions that are taken into consideration are top soil thickness of 11m, weathered rock thickness of 15m and rock density of 2.64 mt/m3.
Pulsed low dose-rate irradiation response in isogenic HNSCC cell lines with different radiosensitivity
Authors: Todorovic Vesna , Prevc Ajda , Zakelj Martina Niksic , Savarin Monika , Bucek Simon , Groselj Blaz , Strojan Primoz , Cemazar Maja , Sersa Gregor 
Published: March 2020

Abstract

Background
Management of locoregionally recurrent head and neck squamous cell carcinomas (HNSCC) is challenging due to potential radioresistance. Pulsed low-dose rate (PLDR) irradiation exploits phenomena of increased radiosensitivity, low-dose hyperradiosensitivity (LDHRS), and inverse dose-rate effect. The purpose of this study was to evaluate LDHRS and the effect of PLDR irradiation in isogenic HNSCC cells with different radiosensitivity.

Materials and methods
Cell survival after different irradiation regimens in isogenic parental FaDu and radioresistant FaDu-RR cells was determined by clonogenic assay; post irradiation cell cycle distribution was studied by flow cytometry; the expression of DNA damage signalling genes was assesed by reverse transcription-quantitative PCR.

Results
Radioresistant Fadu-RR cells displayed LDHRS and were more sensitive to PLDR irradiation than parental FaDu cells. In both cell lines, cell cycle was arrested in G2/M phase 5 hours after irradiation. It was restored 24 hours after irradiation in parental, but not in the radioresistant cells, which were arrested in G1-phase. DNA damage signalling genes were under-expressed in radioresistant compared to parental cells. Irradiation increased DNA damage signalling gene expression in radioresistant cells, while in parental cells only few genes were under-expressed.

Conclusions
We demonstrated LDHRS in isogenic radioresistant cells, but not in the parental cells. Survival of LDHRS-positive radioresistant cells after PLDR was significantly reduced. This reduction in cell survival is associated with variations in DNA damage signalling gene expression observed in response to PLDR most likely through different regulation of cell cycle checkpoints.
Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
Authors: Prevodnik Veronika Kloboves , Marinsek Ziva Pohar , Zalar Janja , Rozina Hermina , Kotnik Nika , Jerman Tine , Varl Jerneja , Ivanus Urska 
Published: March 2020

Abstract

Background
p16/Ki-67 dual immunocytochemical staining (DS) is considered easy to interpret if evaluators are properly trained, however, there is no consensus on what constitutes proper training. In the present study we evaluated a protocol for teaching DS evaluation on students inexperienced in cervical cytology.

Methods
Initial training on 40 DS conventional smears was provided by a senior cytotechnologist experienced in such evaluation. Afterwards, two students evaluated 118 cases. Additional training consisted mainly of discussing discrepant cases from the first evaluation and was followed by evaluation of new 383 cases. Agreement and accuracy of students’ results were compared among the participants and to the results of the reference after both evaluations. We also noted time needed for evaluation of one slide as well as intra-observer variability of the teacher’s results.

Results
At the end of the study, agreement between students and reference was higher compared to those after initial training (overall percent agreement [OPA] 81.4% for each student, kappa 0.512 and 0.527 vs. OPA 78.3% and 87.2%, kappa 0.556 and 0.713, respectively). However, accuracy results differed between the two students. After initial training sensitivity was 4.3% points and 2.9% points higher, respectively compared to the reference, while specificity was 30.6% points and 24.4% points lower, respectively, compared to the reference. At the end of the study, the sensitivity reached by one student was the same as that of the reference, while it was 2.6% points lower for the other student. There was a statistically significant difference in specificity between one student and the reference and also between students (16.7 and 15.1% points). Towards the end of the study, one student needed 5.2 min for evaluating one slide while the other needed 8.2 min. The intra-observer variability of the senior cytotechnologist was in the range of “very good” in both arms of the study.

Conclusions
In teaching DS evaluation, the students’ progress has to be monitored using several criteria like agreement, accuracy and time needed for evaluating one slide. The monitoring process has to continue for a while after students reach satisfactory results in order to assure a continuous good performance. Monitoring of teacher’s performance is also advisable.
Evaluation of quality and reliability of websites about orthognathic surgery using Google Trends™ application
Authors: Dilaver Emrah , Kılınç Delal Dara 
Published: March 2020

Objectives:
Orthognathic surgery is the only treatment option for some cases in orthodontics. Two main goals were aimed in this study. The first goal was to determine the top three keywords that Google searchers look for “orthognathic surgery” using the Google Trends™ application. The second was to assess the quality and reliability of the webpages yielded by searching those four keywords on Google.

Materials and Methods:
Google Trends was searched using the keyword “Orthognathic Surgery.” Then, Google was searched using keywords: “Orthognathic surgery” and the other first three keywords. An oral surgeon and an orthodontist analyzed the quality and reliability of the websites using the DISCERN assessment tool.

Results:
The correlation between evaluators was low. Forty-six of the 70 websites were the websites of different oral and maxillofacial clinics and orthodontic clinics. The percentage of websites was 11% for personal doctor websites, 10% for academic journals, 7% for institutes, 6% for orthodontic clinics, and 1.4% for dental clinics. Overall rating scores of the websites for researchers were 2.41±1.35 for oral surgeon and 1.99±1.49 for orthodontist.

Conclusions:
The reliability and quality of the information in all of the websites was very low. The data on the websites did not have any scientific review processes such as review-peer review.