bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mechanism of teaching–research conflict influencing job burnout among university teachers: The roles of perceived supervisor support and psychological capital
Authors: Heng Shupeng , Yang Ming , Zou Bing , Li Yongzhan , Castaño Gloria 
Published: July 2020

AbstractThis study examined the relationship between teaching–research conflict and job burnout among university teachers and the moderating role of perceived supervisor support (PSS) and psychological capital (PsyCap) in this relationship. Using a cross‐sectional design, data were collected from a convenience sample of 488 university teachers in China. Hierarchical regression analysis was performed to examine the moderating role of PSS and PsyCap in the relationship between teaching–research conflict and job burnout. The results showed that (a) teaching–research conflict was positively linked to emotional exhaustion and depersonalization but negatively linked to personal accomplishment, (b) PSS moderated the effects of teaching–research conflict on both emotional exhaustion and depersonalization but did not act as a moderator in the relationship between teaching–research conflict and personal accomplishment, and (c) PsyCap moderated the effect of teaching–research conflict on all three dimensions of job burnout.
Use of saliva sample to detect C‐reactive protein in children with pneumonia
Authors: Tsai Chih‐Min , Tang Kuo‐Shu , Cheng Ming‐Chou , Liu Ta‐Yu , Huang Ying‐Hsien , Chen Chih‐Cheng , Yu Hong‐Ren 
Published: July 2020

AbstractBackgroundSerum C‐reactive protein (CRP) is a sensitive biomarker for inflammation and is broadly used to clinically diagnose infectious diseases, including pneumonia. However, blood sampling is fraught with technical difficulties in children. The salivary analysis may be a potential diagnostic tool, as it is noninvasive, patient‐friendly, and easy to perform in children. This study aimed to evaluate the use of salivary CRP as a biomarker for children with pneumonia.MethodsA prospective study was conducted in patients aged 2 to 17 years, admitted to the hospital with pneumonia. Saliva and serum samples for CRP and chemokine determination were collected at the initial admission and during a follow‐up from pediatric patients with pneumonia. Salivary samples were also collected from healthy subjects used as controls.ResultsA total of 60 healthy children and 106 pediatric patients with pneumonia were enrolled in this study. The salivary CRP level was much higher in pediatric patients with pneumonia than in healthy children (48.77 ± 5.52 ng/mL vs 14.78 ± 3.92 ng/mL; P < .001). Salivary CRP level was highly correlated with serum CRP level in pediatric patients with pneumonia (r = .679; P < .001). Salivary CRP level (≥40.307 ng/mL) can be used to predict high serum CRP levels (≥80 mg/L) with an area under the curve of 0.810 (95% confidence interval, 0.740–0.881). As pneumonia improved, both salivary and serum CRP levels decreased during follow‐up.ConclusionsSalivary CRP could be an alternative biomarker for serum CRP in pediatric patients with pneumonia. This is especially beneficial for pediatric patients, as saliva collection is simple, noninvasive, and patient‐friendly.
PTEN and ERG expression in MRI‐ultrasound guided fusion biopsy correlated with radical prostatectomy findings in men with prostate cancer
Authors: Erickson Andrew M. , Lokman Utku , Lahdensuo Kanerva , Tornberg Sara , Visapaa Harri , Bergroth Robin , Santti Henrikki , Petas Anssi , Rannikko Antti S. , Mirtti Tuomas 
Published: July 2020

AbstractBackgroundConventional systematic prostate biopsies (SBx) have multiple limitations, and magnetic resonance imaging (MRI)‐ultrasound fusion targeting is increasingly applied (fusion biopsies [FBx]). In our previous studies, we have shown that loss of the tumor suppressor gene phosphatase and tensin homolog (PTEN) in radical prostatectomy (RP) specimens predicts poor disease‐specific survival, and in active surveillance (AS), PTEN loss in SBx predicts an adverse AS outcome, although SBx PTEN status does not correlate well with the corresponding RP status. Here, we have hypothesized that PTEN and erythroblast transformation‐specific related gene (ERG) status in FBx correlate better with RP than they would in SBx.MethodsA total of 106 men, who had undergone FBx and subsequent RP in a single center between June 2015 and May 2017 were included. Fifty‐three of the men had concomitant or previous SBx's. All biopsy and RP specimens were collected, and tissue microarrays (TMA) were constructed from RP specimens. Immunohistochemical stainings for PTEN and ERG expression were conducted on biopsies and RP TMAs and results were compared by using Fisher's exact test.ResultsThe immunohistochemical predictive power of FBx, determined by the concordance of biopsy PTEN and ERG status with RP, is superior to SBx (77.6% vs 66.7% in PTEN, 92.4% vs 66.6% in ERG). FBx was superior to SBx in correlation with RP Gleason Grade Groups and MRI prostate imaging reporting and data system scores.ConclusionFBx grading correlates with RP histology and MRI findings and predicts the biomarker status in the RP specimens more accurately than SBx. A longer follow‐up is needed to evaluate if this translates to better prediction of disease outcomes, especially in AS and radiation therapy where prostatectomy specimens are not available for prognostication.
Current outlook and future research needs for harvest weed seed control in North American cropping systems
Authors: Shergill Lovreet S , Schwartz‐Lazaro Lauren M , Leon Ramon , Ackroyd Victoria J , Flessner Michael L , Bagavathiannan Muthukumar , Everman Wesley , Norsworthy Jason K , VanGessel Mark J , Mirsky Steven B 
Published: July 2020

AbstractHarvest weed seed control (HWSC) comprises a set of tools and tactics that prevents the addition of weed seed to the soil seed bank, attenuating weed infestations and providing a method to combat the development and spread of herbicide‐resistant weed populations. Initial HWSC research efforts in North America are summarized and, combined with the vast area of crops suitable for HWSC, clearly indicate strong potential for this technology. However, potential limitations exist that are not present in Australian cropping systems where HWSC was developed. These include rotations with crops that are not currently amenable to HWSC (e.g. corn), high moisture content at harvest, untimely harvest, and others. Concerns about weeds becoming resistant to HWSC (i.e. adapting) exist, as do shifts in weed species composition, particularly with the diversity of weeds in North America. Currently the potential of HWSC vastly outweighs any drawbacks, necessitating further research. Such expanded efforts should foremost include chaff lining and impact mill commercial scale evaluation, as this will address potential limitations as well as economics. Growers must be integrated into large‐scale, on‐farm research and development activities aimed at alleviating the problems of using HWSC systems in North America and drive greater adoption subsequently. © 2020 Society of Chemical Industry
Baiting location affects anticoagulant rodenticide exposure of non‐target small mammals on farms
Authors: Walther Bernd , Geduhn Anke , Schenke Detlef , Schlötelburg Annika , Jacob Jens 
Published: July 2020

AbstractBACKGROUNDCommensal rodents such as Norway rats (Rattus norvegicus Berk.), black rats (R. rattus L.) and house mice (Mus musculus L.) damage stored produce and infrastructure, cause hygienic problems and transmit zoonotic pathogens to humans. The management of commensal rodents relies mainly on the use of anticoagulant rodenticides (ARs). ARs are persistent and bio‐accumulative, which can cause exposure of non‐target species. We compared the baiting strategies to use brodifacoum (BR) in bait boxes indoors only versus in and around buildings in replicated field trials at livestock farms to assess resulting BR residues in non‐target small mammals.RESULTSWhen bait was used indoors only, the percentage of trapped non‐target small mammals with BR residues as well as BR concentration in liver tissue was about 50% lower in comparison to bait application in and around buildings. These effects occurred in murid rodents and shrews but not in voles that were generally only mildly exposed. During the baiting period, BR concentration in murids was stable but decreased by about 50% in shrews.CONCLUSIONRestricting the application of BR bait to indoors only can reduce exposure of non‐target species. The positive effect of this baiting strategy on non‐target species needs to be balanced with the need for an effective pest rodent management within a reasonable time. More research is needed to clarify which management approaches strike this balance best.
The role of population and quantitative genetics and modern sequencing technologies to understand evolved herbicide resistance and weed fitness
Authors: Leon Ramon G , Dunne Jeffrey C , Gould Fred 
Published: July 2020

AbstractEvolution of resistance to multiple herbicides with different sites of action and of nontarget site resistance (NTSR) often involves multiple genes. Thus, single‐gene analyses, typical in studies of target site resistance, are not sufficient for understanding the genetic architecture and dynamics of NTSR and multiple resistance. The genetics of weed adaptation to varied agricultural environments is also generally expected to be polygenic. Recent advances in whole‐genome sequencing as well as bioinformatic and statistical tools have made it possible to use population and quantitative genetics methods to expand our understanding of how resistance and other traits important for weed adaptation are genetically controlled at the individual and population levels, and to predict responses to selection pressure by herbicides and other environmental factors. The use of tools such as quantitative trait loci mapping, genome‐wide association studies, and genomic prediction will allow pest management scientists to better explain how pests adapt to control tools and how specific genotypes thrive and spread across agroecosystems and other human‐disturbed systems. The challenge will be to use this knowledge in developing integrated weed management systems that inhibit broad resistance to current and future weed‐control methods. © 2020 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Stratospheric influence on ECMWF sub‐seasonal forecast skill for energy‐industry‐relevant surface weather in European countries
Authors: Büeler Dominik , Beerli Remo , Wernli Heini , Grams Christian M. 
Published: July 2020

AbstractMeteorologists in the energy industry increasingly draw upon the potential for enhanced sub‐seasonal predictability of European surface weather following anomalous states of the winter stratospheric polar vortex (SPV). How the link between the SPV and the large‐scale tropospheric flow translates into forecast skill for surface weather in individual countries – a spatial scale that is particularly relevant for the energy industry – remains an open question. Here we quantify the effect of anomalously strong and weak SPV states at forecast initial time on the probabilistic extended‐range reforecast skill of the European Centre for Medium‐Range Weather Forecasts (ECMWF) in predicting country‐ and month‐ahead‐averaged anomalies of 2 m temperature, 10 m wind speed, and precipitation. After anomalous SPV states, specific surface weather anomalies emerge, which resemble the opposing phases of the North Atlantic Oscillation. We find that forecast skill is, to first order, only enhanced for countries that are entirely affected by these anomalies. However, the model has a flow‐dependent bias for 2 m temperature (T2M): it predicts the warm conditions in Western, Central and Southern Europe following strong SPV states well, but is overconfident with respect to the warm anomaly in Scandinavia. Vice versa, it predicts the cold anomaly in Scandinavia following weak SPV states well, but struggles to capture the strongly varying extent of the cold air masses into Central and Southern Europe. This tends to reduce skill (in some cases significantly) for Scandinavian countries following strong SPV states, and most pronounced, for many Central, Southern European, and Balkan countries following weak SPV states. As most of the weak SPV states are associated with sudden stratospheric warmings (SSWs), our study thus advices particular caution when interpreting sub‐seasonal regional T2M forecasts following SSWs. In contrast, it suggests that the model benefits from enhanced predictability for a considerable part of Europe following strong SPV states.
Efficient Qubit Routing for a Globally Connected Trapped Ion Quantum Computer
Authors: Webber Mark , Herbert Steven , Weidt Sebastian , Hensinger Winfried K. 
Published: July 2020

AbstractThe cost of enabling connectivity in noisy intermediate‐scale quantum (NISQ) devices is an important factor in determining computational power. A qubit routing algorithm is created, which enables efficient global connectivity in a previously proposed trapped ion quantum computing architecture. The routing algorithm is characterized by comparison against both a strict lower bound, and a positional swap based routing algorithm. An error model is proposed, which can be used to estimate the achievable circuit depth and quantum volume of the device as a function of experimental parameters. A new metric based on quantum volume, but with native two‐qubit gates, is used to assess the cost of connectivity relative to the upper bound of free, all to all connectivity. The metric is also used to assess a square‐grid superconducting device. These two architectures are compared and it is found that for the shuttling parameters used, the trapped ion design has a substantially lower cost associated with connectivity.
Controllability and stabilization of Boolean control networks by the auxiliary function of flipping
Authors: Chen Bingquan , Yang Xingyue , Liu Yang , Qiu Jianlong 
Published: July 2020

SummaryIn this article, a hybrid method combining flip matrix approach and an open (or closed) loop control is proposed to study global controllability and stabilization of Boolean control networks (BCNs). First, the necessary and sufficient condition for global controllability of BCNs, by flipping some members of a perturbation set and under free control sequences, is proposed. After that, using a search algorithm, the minimal perturbation sets for global controllability (MS‐GCs) of the BCN are obtained. Next, we propose a necessary and sufficient criterion for global stabilization of BCNs by flipping some members of a perturbation set and under a state feedback control. Similarly, an algorithm is given to search for the minimal perturbation sets for global stabilization (MS‐GSs) of the BCN. Moreover, the time‐optimal MS‐GSs of the BCN are also obtained by an algorithm. Some examples are given to illustrate the effectiveness of the results.
H∞ control for uncertain one‐sided Lipschitz nonlinear systems in finite frequency domain
Authors: Saad Wajdi , Sellami Anis , Garcia Germain 
Published: July 2020

SummaryThe current article discusses the H∞ disturbance attenuation control design problem for one‐sided Lipschitz systems in finite frequency domain. Models containing norm‐bounded parameter uncertainties, disturbances, and input nonlinearities are considered. By contrast to existing full frequency methods, the H∞ controller is computed depending on the frequency ranges of disturbances. The finite frequency disturbance attenuation index is initially defined. Thanks to Finsler's lemma, sufficient and less conservative analysis conditions are also derived for the closed‐loop system. Then, synthesis conditions in the low, middle, and high frequency ranges as well as the whole frequency range, are formulated in terms of linear matrix inequalities. At last, to prove the effectiveness and the superiority of the proposed approach, a physical example is used and a comparative study is done.
Simulation‐based estimation of the early spread of COVID‐19 in Iran: actual versus confirmed cases
Authors: Ghaffarzadegan Navid , Rahmandad Hazhir 
Published: July 2020

AbstractUnderstanding the state of the COVID‐19 pandemic relies on infection and mortality data. Yet official data may underestimate the actual cases due to limited symptoms and testing capacity. We offer a simulation‐based approach which combines various sources of data to estimate the magnitude of outbreak. Early in the epidemic we applied the method to Iran's case, an epicenter of the pandemic in winter 2020. Estimates using data up to March 20th, 2020, point to 916,000 (90% UI: 508 K, 1.5 M) cumulative cases and 15,485 (90% UI: 8.4 K, 25.8 K) total deaths, numbers an order of magnitude higher than official statistics. Our projections suggest that absent strong sustaining of contact reductions the epidemic may resurface. We also use data and studies from the succeeding months to reflect on the quality of original estimates. Our proposed approach can be used for similar cases elsewhere to provide a more accurate, early, estimate of outbreak state.© 2020 System Dynamics Society
Mechano‐Informed Biomimetic Polymer Scaffolds by Incorporating Self‐Powered Zinc Oxide Nanogenerators Enhance Motor Recovery and Neural Function
Authors: Qian Yun , Cheng Yuan , Song Jialin , Xu Yang , Yuan Wei‐En , Fan Cunyi , Zheng Xianyou 
Published: July 2020

AbstractPiezoelectric materials can produce electrical power from the mechanical stimulation and thus, they may accelerate electroactive tissue healing as a promising treatment for traumatic peripheral nerve injuries. In this study, a piezoelectric zinc oxide nanogenerator scaffold is manufactured by 3D injectable multilayer biofabrication. The piezoelectric polymeric scaffold displays desirable mechanical and physical characteristics, such as aligned porosity, high elasticity, scaffold stiffness, surface energy, and excellent shear behavior. In addition, its biocompatibility supplies Schwann cells with an adhesive, proliferative, and angiogenic interface, as is reflected by higher expression of functional proteins including nerve growth factor (NGF) and vascular endothelial growth factor (VEGF). In vivo mechanical stimuli by treadmill practice contribute to the comprehensive reparative therapy. The piezoelectric conduit accelerates nerve conducting velocity, promotes axonal remyelination, and restores motor function by recovering endplate muscles. Moreover, the piezoelectric nanogenerator scaffold creates biomimetic electrically conductive microenvironment without causing noticeable toxicity to functioning organs and improves peripheral nerve restoration by the multifunctional characteristics. Therefore, the mechano‐informed biomimetic piezoelectric scaffold may have enormous potential in the neuroengineering for regenerative medicine.
Circulating nutrients and hematological parameters in managed African elephants (Loxodonta Africana) over a 1‐year period
Authors: Wood Jordan , Koutsos Elizabeth , Kendall Corinne J. , Minter Larry J. , Tollefson Troy , Ivory Erin , Ange‐van Heugten Kimberly 
Published: July 2020

AbstractAfrican elephants (Loxodonta Africana) are currently considered a vulnerable species. One key to improving methods of species management is to better monitor and understand elephant nutrition. Analyzing circulating nutrients is one of the best and least invasive methods of monitoring managed elephant nutrition, but limited reference values are available. This study examined the circulating basic hematology concentrations, minerals, vitamins A, D, and E, and fatty acids of six African elephants (two males and four females) at the North Carolina Zoo collected monthly from March 2016 to April 2017 and compared levels among seasons. Creatinine (CRE) and albumin had seasonal differences (p ≤ .05). Calcium, magnesium, phosphorus, potassium, selenium, zinc, cobalt, manganese, and molybdenum displayed seasonal differences (p ≤ .05). Retinol and 25‐hydroxyvitamin D2 had seasonal differences (p ≤ .05). Linoleic acid, α‐linolenic acid, arachidonic acid, total omega‐3 fatty acids, total omega‐6 fatty acids, and the omega‐6 to omega‐3 ratio showed seasonal differences (p ≤ .05). Findings suggest that exogenous vitamin E supplements may not be necessary with a mixed feedstuff diet (hay, fortified concentrate pellet, browse, and produce) based on circulating values. This data offer updated information on circulating reference values and novel circulating concentrations of nutrients for Southeastern US managed African elephants that can be used to inform nutritional and health management in all similar habitats.
Holographic entanglement entropy in anisotropic background with confinement-deconfinement phase transition
Authors: Aref’eva Irina Ya. , Patrushev Alexander , Slepov Pavel 
Published: July 2020

AbstractWe discuss a general five-dimensional completely anisotropic holographic model with three different spatial scale factors, characterized by a Van der Waals-like phase transition between small and large black holes. A peculiar feature of the model is the relation between anisotropy of the background and anisotropy of the colliding heavy ions geometry. We calculate the holographic entanglement entropy (HEE) of the slab-shaped region, the orientation of which relatively to the beams line and the impact parameter is characterized by the Euler angles. We study the dependences of the HEE and its density on the thermodynamic (temperature, chemical potential) and geometric (parameters of anisotropy, thickness, and orientation of entangled regions) parameters. As a particular case the model with two equal transversal scaling factors is considered. This model is supported by the dilaton and two Maxwell fields. In this case we discuss the HEE and its density in detail: interesting features of this model are jumps of the entanglement entropy and its density near the line of the small/large black hole phase transition. These jumps depend on the anisotropy parameter, chemical potential, and orientation. We also discuss different definitions and behavior of c-functions in this model. The c-function calculated in the Einstein frame decreases while ℓ is increasing for all ℓ in the isotropic case (in regions of (μ, T)-plane far away from the line of the phase transition). We find the non-monotonicity of the c-functions for several anisotropic configurations, which however does not contradict with any of the existing c-theorems since they all are based on Lorentz invariance.