bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional traits of particle-associated microbial assemblages in the low-latitude Pacific Ocean
Authors: Takami Hideto , Tada Yuya , Okubo Takashi , Arai Wataru , Ogura Yoshitoshi , Hayashi Tetsuya , Suzuki Shotaro , Hamasaki Koji 
Published: January 2020

Abstract
Background Organic particles are hotspots for microbial activity and serve as sites of organic matter mineralisation in the water column of marine systems. In nutrient-limited surface water, degradation of organic matter and nutrient regeneration by marine microbes is crucial. Although free-living (FL) bacteria vastly outnumber those on particles, particle-associated (PA) bacteria can reach locally higher concentrations. Accordingly, to achieve a better understanding of marine microbial ecosystems, it is important to elucidate the differences in not only microbial community structures, but also functional traits, between PA and FL environmental sample fractions. In a previous study, we demonstrated that the Genomaple (formerly MAPLE) system could successfully differentiate the functional potentials and diversity of contributors to each function in four metagenomic datasets generated by the Global Ocean Sampling expedition. Hence, we also used this system to highlight functional traits in PA microbial assemblages. Results The PA and FL fractions could be distinguished from one another by their taxonomic compositions, inferred from ribosomal proteins and relative abundance of module functions. Module functions that were more abundant among PA assemblages than FL assemblages were shared between both subtropical gyres, and their taxonomic compositions were similar. Bacterial transport systems associated with adhesive molecules used for forming microbial assemblages through particulate organic matter were more abundant in the PA fractions. Bacterial regulatory system elements for C 4 -dicarboxylate transport and B-vitamin biosynthesis were also abundant among PA assemblages, suggesting mutual relationships between bacteria and algae involved in exchange of nutrient sources. On the other hand, module functions related to amino acid biosynthesis and bacterial transport systems for inorganic nitrogen, phosphorus, and urea were significantly more abundant in the PA assemblages of more oligotrophic North and South Pacific subtropical gyres than eastern equatorial Pacific regions. Conclusions Comprehensive functional metagenomic analyses based on functional abundance revealed some notable functional traits in PA assemblages related to cell adhesion and nutrient acquisition, enabling the microbes to survive in subtropical regions that are more oligotrophic than the equatorial regions.
Hospitalidade em sentido próprio e figurado
Authors: Gotman Anne 
Published: January 2020

Neste texto de palestra de abertura de seminário realizado em outubro de 2.000, na França, sobre o tema da hospitalidade urbana, Anne Gotman parte da distinção entre o que ela chama de hospitalidade em sentido próprio, o acolhimento pessoa a pessoa, que se refere a práticas privadas para a maioria, baseadas na obrigação de reciprocidade, da hospitalidade em sentido figurado, que se refere à ideia de hospitalidade que transparece quando dizemos que um local ou instituição é hospitaleiro (ou inospitaleiro) e que designa práticas suscetíveis de se desenvolver à margem da solidariedade e dos serviços públicos. No primeiro caso, tratam-se de situações e usos reconhecidos como tais, ainda que pouco explorados. No segundo caso, trata-se sobretudo de uma perspectiva e abordagem diferente sobre os trabalhos de pesquisa existentes que pretendemos reexaminar. A autora avança, ainda, para o conceito de hospitalidade mínima garantida, que abrange grosso modo o direito de asilo concedido a estrangeiros e antigamente aos pobres e hoje às categorias asseguráveis ou vulneráveis a quem Estado ou a comunidade fornecem proteção e segurança
Turismo e patrimônio cultural: revisitando uma polêmica típica por meio de pratos típicos
Authors: Graeff Lucas , Zottis Alexandra Marcella 
Published: January 2020

Este trabalho trata da dinamização de produtos e práticas gastronômicaspela categoria patrimônio com vistas ao turismo cultural. Trata-se de um artigocomparando as propostas de patrimonialização do menarosto e do galeto al primocanto como pratos típicos de dois municípios do estado do Rio Grande do Sul, nosul do Brasil. O argumento é de que a patrimonialização desses pratos responde àreprodução social do grupo e, por consequência, as dimensões econômica e simbólica não se contradizem necessariamente. Nos dois casos estudados, essas duas dimensões imbricam-se na produção de uma narrativa civilizacional de persistência, de duração e de um sentido identitário comum.
Behavior of parents and educators following traumatic injury to young permanent teeth of children in Joinville, Santa Catarina
Authors: Lima Jennyffer Samira de , Dalprá Jaini , Almeida Susimara Braga de 
Published: January 2020

Introduction: Traumatic dental injuries are a major public health problem, especially in the age range of 7 to 15 years, when young permanent teeth are established. Objective: To evaluate the behavior of parents of children who attend public or private school and their educators, in cases of traumatic injury to young permanent teeth and to evaluate whether they sought emergency guidance, in the city of Joinville, Santa Catarina, Brazil. Evaluation was carriedout via a questionnaire for asking the parents and teachers about their knowledge of dental trauma. Material and methods: A total of 248 parents and 22 teachers participated in the study. Out of all the participants that completed the questionnaire with questions on previous trauma experience, avulsion behavior, avulsed tooth storage medium, and time elapsed from dental trauma until care, 49.6% of had higher education. The data were tabulated on a Microsoft Office Excel 365 worksheet, and the chi-square statistical test wasapplied. Results: The research showed that 91.8% of parents and8.2% of educators from both public and private schools had minimalknowledge regarding dental trauma. Many of the participants (73.2%) were unaware of what dental reimplantation was and lacked knowledge regarding storage choices for a dental element. Instead, 68% preferred to take the child to a dental surgeon to receive emergency care. Conclusion: The knowledge parents and educators of public and private schools have about dental trauma is limited. Education on this subject needs to be promoted for enabling parents andeducators to make informed decisions to ensure the best prognosis after traumatic dental injury.
Atividade antimicrobiana de extratos etanólicos de Banisteriopsis anisandra (Malpighiaceae) e interações medicamentosas Antimicrobial activity of ethanol extracts of Banisteriopsis anisandra (Malpighiaceae) and drug interactions
Authors: Ferreira Igor Valdivia , Mendes-Costa Maria Cristina 
Published: January 2020

Introdução: A planta Banisteriopsis anisandra A. Juss é uma espécie medicinal pouco conhecida e estudada, mas já demonstrou potencial para utilização na odontologia. Objetivo: Avaliar a atividade antimicrobiana de B. anisandra e o potencial para interações medicamentosas com fármacos relacionados à saúde bucal. Material e métodos: Foi obtido o extrato etanólico bruto das folhas de B.anisandra, e diluições em série foram testadas contra Candida albicans (ATCC 10231), Streptococcus mutans (ATCC 25175), Streptococcus salivarius (ATCC 7073) e Staphylococcus aureus (ATCC 6538). Como controle positivo foram utilizados os antibióticos ampicilina (10 μg/ml), amoxilina (10 μg/ml) e penicilina (30 μg/ml), para as cepas bacterianas; e o antifúngico cetoconazol (2 mg/ml), para a levedura. Compararam-se a eficiência e a sensibilidade do método de difusão em meio sólido e do método de difusão em meio líquido, e foi determinada a concentração inibitória mínima (CIM), assim como foram avaliadas as interações medicamentosas dos extratos com os antibióticos. Resultados: O método de microdiluição em caldo mostrou-se mais sensível que o método de difusão em disco, sendo, portanto, mais confiável, além de usar menos quantidade de material. Houve interação medicamentosa positiva dos extratos com os antibióticos e com o cetoconazol nas concentrações de 1:2 para o extrato. A bactéria S. aureus e a levedura C. albicans mostraram-se sensíveis ao extrato da planta na diluição 1:1 nos testes de difusão em disco, e o antibiótico penicilina não se revelou eficaz em nenhuma das bactérias testadas. Conclusão: O extrato etanólico de B. anisandra tem potencial antimicrobiano e interação medicamentosa com fármacos relacionados à saúde bucal. Existem raros estudos sobre as propriedades farmacológicas de B. anisandra, e os resultados são os primeiros relatos sobre sua atividade antimicrobiana em associação com antibióticos e antifúngicos.
Removal of obturation material in endodontic retreatment: a literature review
Authors: Menezes Carina Do Nascimento , Carneiro Verydianna Frota , Vale Mônica Sampaio do 
Published: January 2020

Introduction: Removal of filling material from the root canal system is required when a previous endodontic treatment fails, what may result in the permanence of an unfavorable periapical condition. The intent is to completely remove the filling material inside of the root canal to achieve sufficient cleaning and shaping for successful retreatment. Objective: The aims of this article were to provide asystematic review of the different techniques of endodontic filling material associated or not with organic solvents and to analyze them critically in terms of advantages and disadvantages of each technique. Literature review: The descriptors used were “guttapercha”, “obturation,” and “retreatment” in the following databases: PubMed, MEDLINE, Latin American and Caribbean Center on Health Sciences Information (Bireme), Latin-American and CaribbeanHealth Sciences (Lilacs), Brazilian Dentistry Bibliography (BBO), and Scientific Electronic Library Online (SciELO). Publications of in vitro/ ex vivo and in vivo experiments without language restriction between the years 2010 and 2018 were selected. Conclusion: None of the techniques were capable of performing complete root canal cleaning, and the manual method was so effective as the automated method, although it requires longer working time. Furthermore, although this review confirmed that the solvent action did not allow a significantimprovement in the removal of the filling material, ultrasoundactivated irrigation proved to be an efficient adjunctive device as it could significantly reduce the volume of intracanal residuals.
Rânula mergulhante extensa em paciente pediátrico tratado com micromarsupialização: relato de caso Extense plunging ranula in pediatric patient treated with micro-marsupialization: a case report
Authors: Gonçalves Kalyne Kelly Negromonte , Santos Marcelo Soares dos , Alves Silva Joana De Ângelis , Lira Correia Andreza Veruska 
Published: January 2020

Introdução: O termo rânula é usado para descrever um aumento de volume difuso no assoalho da boca causado por um extravasamento mucoso ou um cisto de retenção de muco derivado das principais glândulas salivares sublinguais ou submandibulares. A rânula pode ser simples ou mergulhante, quando a pressão do fluido disseca através do músculo milo-hioideo para o espaço submandibular.Objetivo: Relatar um caso de rânula mergulhante extensa em paciente pediátrico tratado por micromarsupialização. Relato de caso: Criança do sexo masculino compareceu ao Hospital da Restauração, Recife (PE), com queixa de tumefação intraoral, submentual e submandibular esquerda com evolução de uma semana. Observou-se extenso aumento de volume em região de soalho bucal de cor azulada, textura lisa e com foco central ulcerado. Com base nos aspectos clínicos e imaginológicos e na história da doença, o diagnóstico de rânula mergulhante foi realizado. Optou-se pela técnica de micromarsupialização, sob anestesia local, com utilização de fio reabsorvível à base de poliglactina. Paciente segue em acompanhamento de seis meses, sem sinais de recidiva da lesão. Conclusão: Visando a um procedimento mais simples e de baixa morbidade, a micromarsupialização mostra-se uma alternativa de tratamento viável e com bons resultados quando bem indicada, principalmente em crianças.
Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy
Authors: Zhu Shunqin , Yu Qin , Huo Chunsong , Li Yuanpeng , He Linshen , Ran Botian , Chen Ji , Li Yonghao , Liu Wanhong 
Published: January 2020

Background:
Artemisinin is a sesquiterpene lactone compound with a special peroxide
bridge that is tightly linked to the cytotoxicity involved in fighting malaria and cancer. Artemisinin
and its derivatives (ARTs) are considered to be potential anticancer drugs that promote cancer cell
apoptosis, induce cell cycle arrest and autophagy, inhibit cancer cell invasion and migration. Additionally,
ARTs significantly increase intracellular Reactive Oxygen Species (ROS) in cancer cells,
which result in ferroptosis, a new form of cell death, depending on the ferritin concentration. Ferroptosis
is regarded as a cancer suppressor and as well as considered a new mechanism for cancer therapy.

Methods:
The anticancer activities of ARTs and reference molecules were compared by literature
search and analysis. The latest research progress on ferroptosis was described, with a special focus on
the molecular mechanism of artemisinin-induced ferroptosis.

Results:
Artemisinin derivatives, artemisinin-derived dimers, hybrids and artemisinin-transferrin
conjugates, could significantly improve anticancer activity, and their IC50 values are lower than those
of reference molecules such as doxorubicin and paclitaxel. The biological activities of linkers in dimers
and hybrids are important in the drug design processes. ARTs induce ferroptosis mainly by
triggering intracellular ROS production, promoting the lysosomal degradation of ferritin and regulating
the System Xc-/Gpx4 axis. Interestingly, ARTs also stimulate the feedback inhibition pathway.

Conclusion:
Artemisinin and its derivatives could be used in the future as cancer therapies with
broader applications due to their induction of ferroptosis. Meanwhile, more attention should be paid
to the development of novel artemisinin-related drugs based on the mechanism of artemisinininduced
ferroptosis.
THE RELATIONSHIP BETWEEN THE ABILITY TO PERFORM ACTIVITIES OF DAILY LIVING WITH RISK FOR FALLS AMONG OLDER ADULTS IN TRESNA WERDHA SOCIAL SERVICE BANYUWANGI
Authors: Nisa Luthfi Fadlilatun , Aini Latifa , Rosyidi Kholid 
Published: January 2020

Increasing number of older adults makes them less productive which causes a decline in their independence to perform the activities of daily living. One of the physical problems that causes morbidity and mortality among older adults is fall. The purpose of this research was to analyse the relationship between the ability to perform activities of daily living and risk for falls among older adults in Tresna Werdha Banyuwangi. This research applied non experimental correlational design and cross sectional approach. The objects of research were 71 older adults. The sample was taken using total sampling which was comprised of 65 older adults that fulfilled inclusion criteria. Katz Index, Morse Fall Scale (MFS), and observation sheet were used to collect the data. Those data analysed using chi square test. The result of the older adults ability in performing activities in daily living showed that categorised as mild and the mildest dependent 17 older adultsÂ (26,1%)Â with low and high risk of falls were. Test resulted in p value 0,002 (p <Î± = 0,05) which suggested that there was a relationship between the ability to perform activities of daily living and risk for falls. Medical staff are expected to provide nursing care in addressing risk for falls, providing ambulatory aidÂ to help maintaining balance while walking, teaching the patients what to do when they fall, so they donâ€™t suffer serious injury, by monitoring the movement, and by holding a routine physical program.Â
Analysis of Funding, Education Performance, and Economic Growth in Indonesia
Authors: Arham Muhammad Amir , Dai Sri Indriyani S. 
Published: January 2020

Abstract: Higher education budget allocations affect educational performance, and it also can improve human capital to boost the economic growth of a nation. Concerning this, the present study was implemented to find out the extent of educational performance effect towards the economic growth, and what variables are the most influential determinants to boost economic growth in Indonesia related to educational sector. Fixed effect approach through data panel was used to analyze the secondary data obtained from 34 provinces in Indonesia from 2014 to 2016. The result showed that educational performance in each province in Indonesia measured by using the pure participation rate of junior high school students and high school graduates and higher education graduates were able to increase the economic growth with the assumption that their skills were sufficient to increase productivity, whereas, crude participation rate of junior high school, senior high school graduates, and higher education graduates can be an obstacle to economic development. Also, the determinant factor to boost economic growth was public spending on education sector. Keywords: funding, education performance, economic growthAnalisis Pembiayaan, Kinerja Pendidikan, dan Pertumbuhan Ekonomi di IndonesiaAbstrak: Alokasi anggaran pendidikan yang makin besar memberikan efek terhadap kinerja pendidikan sekaligus memperbaiki mutu manusia yang dapat mendorong laju pertumbuhan ekonomi. Dalam kaitannya dengan hal tersebut studi ini dilakukan dengan tujuan untuk melihat seberapa besar pengaruh kinerja pendidikan terhadap pertumbuhan ekonomi dan variabel apa saja yang memiliki determinasi paling kuat mendorong pertumbuhan ekonomi di Indonesia yang terkait dengan sektor pendidikan. Metode analisis yang digunakan adalah panel data melalui pendekatan fixed effect, dengan menggunakan data sekunder untuk 34 provinsi di Indonesia selama periode 2014 – 2016. Hasil analisis menunjukkan bahwa kinerja pendidikan setiap provinsi di Indonesia yang diukur dari APM SLTP dan tamatan SLTA dapat meningkatkan pertumbuhan ekonomi dengan asumsi bahwa keterampilan mereka cukup memadai untuk meningkatkan produktivitas, sementara APK SLTP, lulusan SLTP dan lulusan perguruan tinggi dapat mengganggu pertumbuhan ekonomi. Sedangkan faktor determinan mendorong pertumbuhan ekonomi adalah variabel belanja publik sektor pendidikan. Kata Kunci: pembiayaan, kinerja pendidikan, pertumbuhan ekonomi
The Mobile Payment Fintech Continuance Usage Intention in Indonesia
Authors: Putritama Afrida 
Published: January 2020

Abstract: This research aimed to determine both positive and negative factors influencing the continuance usage intention of mobile payment FinTech in Indonesia. This research used an exploratory sequential mixed methods research design with a questionnaire as the first research instrument followed by semi-structured interviews. This research found that both the perceived benefit and perceived risk significantly influenced the mobile payment FinTech continuance usage intention in Indonesia but, the perceived benefit had a stronger impact than the perceived risk. Convenience had the most substantial positive impact on the perceived benefit, which later increased the mobile payment FinTech continuance usage intention. Financial risk had the strongest influence on the perceived risk, which later reduces the mobile payment FinTech continuance usage intention. Keywords: mobile payment FinTech, continuance usage intention, Indonesian consumerNiat Penggunaan Berkelanjutan dari Pembayaran Seluler Fintech di Indonesia Abstrak: Tujuan dari penelitian ini adalah untuk menentukan faktor-faktor positif dan negatif yang mempengaruhi niat penggunaan berkelanjutan dari pembayaran seluler FinTech di Indonesia. Penelitian ini menggunakan desain penelitian metode campuran sekuensial eksploratori dengan kuesioner sebagai instrumen penelitian pertama diikuti oleh wawancara semi-terstruktur. Penelitian ini menemukan bahwa baik manfaat yang dirasakan maupun risiko yang dirasakan secara signifikan mempengaruhi kelanjutan penggunaan pembayaran seluler FinTech di Indonesia tetapi manfaat yang dirasakan memiliki dampak yang lebih kuat daripada risiko yang dirasakan. Kenyamanan memiliki dampak positif yang paling kuat pada manfaat yang dirasakan, yang kemudian meningkatkan niat kelanjutan penggunaan pembayaran seluler FinTech. Risiko keuangan memiliki pengaruh paling kuat pada risiko yang dirasakan, yang kemudian mengurangi niat kelanjutan penggunaan pembayaran seluler FinTech. Kata kunci: mobile payment FinTech, niat kelanjutan penggunaan, konsumen Indonesia
SPECTROSCOPIC CHARACTERIZATION OF PHYTOCONSTITUENTS ISOLATED FROM A RARE MANGROVE AEGIALITIS ROTUNDIFOLIA ROXB., LEAVES AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE CRUDE EXTRACT
Authors: DEBJIT GHOSH  , SUMANTA MONDAL  , K. RAMAKRISHNA  
Published: January 2020

Objective: The aim of the study is to isolate and characterize the phytochemicals from the leaves of a rare and unexplored mangrove Aegialitis rotundifolia and evaluate the antimicrobial properties of the crude extract.
Methods: The dried powdered plant material was extracted with ethanol, and the ethanol extract obtained was dissolved in distilled water and partitioned using n-hexane first and then ethyl acetate. The ethyl acetate fraction was subjected to column chromatography for isolation of phytocompounds. The isolated compounds were characterized using infrared (IR), carbon-13 nuclear magnetic resonance (13C NMR), proton nuclear magnetic resonance (1H NMR), mass spectroscopy, and thin-layer chromatography (TLC). Antimicrobial activity of the crude extracts was performed using the well diffusion method against four bacterial strains and two fungal strains.
Results: Three pure compounds were isolated from the leaves of Aegialitis rotundifolia, namely, 3,4-dimethyl benzoic acid, 3’-methoxy-4’-hydroxy-flavan-3-ol, and 3’,7-dimethoxy-dimethyl-4’,3,5-trihydroxy flavone which were confirmed by spectroscopic studies. Strong antibacterial activity was shown by the test extract against Staphylococcus aureus and Pseudomonas aeruginosa, whereas Escherichia coli and Bacillus cereus showed average and nil activity, respectively. The antifungal activity of the test extract was found to be strong for both the fungal strains, namely, Candida albicans and Aspergillus niger.
Conclusion: The results of the present study show that the isolated compounds were confirmed to be 3,4-dimethyl benzoic acid, 3’-methoxy-4’- hydroxy-flavan-3-ol, and 3’,7-dimethoxy-dimethyl-4’,3,5-trihydroxy flavone and the test extracts showed potent antimicrobial activity for all the bacterial and fungal strains except E. coli and B. cereus which showed average and nil activity, respectively.