bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiplikasi tunas kunyit putih (Kaempferia rotunda L.) pada jenis dan konsentrasi sitokinin secara in vitro
Authors: Murgayanti MURGAYANTI , Sumadi Sumadi , N Ramadhanti F 
Published: December 2020

Kunyit putih merupakan tanaman obat yang bermanfaat dan perlu dibudidayakan lebih luas namun terkendala oleh penyediaan bibit bermutu yang terbatas. Perbanyakan tanaman dengan cara konvensional yang dilakukan turun temurun dan terinfeksi patogen menyebabkan kualitas rimpang menurun. Perbanyakan secara in vitro dapat mengatasi kelangkaan bibit kunyit putih yang bermutu tinggi dalam jumlah besar dan bebas patogen. Ketersediaan bibit unggul yang dihasilkan secara in vitro bergantung pada jenis dan konsentrasi sitokinin yang ditambahkan pada media kultur. Tujuan penelitian adalah untuk menetapkan jenis dan konsentrasi sitokinin yang paling baik pengaruhnya terhadap pertumbuhan tunas kunyit putih (Kaempferia rotunda L.) secara in vitro. Percobaan dilakukan di Laboratorium Kultur Jaringan, Fakultas Pertanian, Universitas Padjadjaran yang berlangsung pada bulan Agustus 2019 – April 2020. Bahan tanam berasal dari tunas rimpang yang berukuran ±0,5-1,0 cm. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) 10 perlakuan dengan 3 kali ulangan. Media yang digunakan adalah Murashige and Skoog (MS) dengan perlakuan jenis sitokinin Benzil Amino Purine (BAP), 2-Isopenteniladenina (2-iP) konsentrasi 1.5; 3.0; dan 4.5 ppm dan Thidiazuron (TDZ) konsentrasi 0.15; 0.30; 0.45 ppm. Hasil percobaan menunjukkan terdapat pengaruh yang berbeda dalam memacu dan merangsang pemunculan jumlah tunas, tinggi tanaman, dan panjang akar pada tunas kunyit putih secara in vitro. Pemberian 0.45 ppm Thidiazuron pada media MS memberikan pengaruh terbaik dalam menghasilkan jumlah tunas. Kata Kunci: Tunas Rimpang, Perbanyakan, Kaempferia rotunda, Sitokinin
The Impacts of Urban Expansion on Livelihoods of the Surrounding Rural Society: The Case of Tefki Town, Oromia Special Zone Surrounding Finfinne
Authors: Worku Gadisa 
Published: December 2020

Urbanization is recently a rising trend seen all over the world, mostly in an upsetting rate in developing countries. Similarly, most towns in Ethiopia are recently becoming expanded towards the adjacent rural societies. The Expansions of these towns were resulted in the consuming and conversion of farm land to urban land uses and affects the agrarian livelihoods. This study is intended to assess the impacts of urban expansion on livelihoods of the society surrounding rural kebeles of Tefki town from the year 2015-2019. Specifically, the study focused on evaluating the effects of town expansion on the farmers (households) in terms of income, the opportunities of the affected households secured from the town expansion and compensation process. Hence, 166 expansion affected households were selected through snowball sampling, and also (5) officials from different institutions were purposively taken for key informant interview while (7) respondents from the affected farmers were selected for interview. Thus, the primary data were collected using questionnaires and interview. Secondary data have been also used to triangulate and supplement the first hand information. The collected data were analyzed by using SPSS version 20. The result showed that Tefki town rapidly expanded during the last five years as a result of population growth and industrialization. This expansion made significant effects on livelihoods of the surrounding farmers. Although they secured access to certain services, it was also brought effects like loss of agricultural land and other assets including grazing land which resulted in change of their livelihoods, and unfair compensation. This expansion has made the households of the surrounding area to lose farm land on which their livelihood used to depend on for long period of time. Every farmer has been made to lose an average of 1 hectare of their owned farm land. The grazing land of the area has been decreased because of town expansion, and thus made farmers to lack enough place of grazing for their livestock. On the other side, the compensation was not made on time for the affected farmers. The study also found out that the compensation given to the farmers was not fair, and too inadequate to sustain the livelihoods of the affected households. Therefore, a detailed potential effect assessment study should be carried out by the government and other stakeholders prior to implementing urbanization programs so as to minimize the adverse effects of urban expansion.
Personal Branding and Behavioural Changes among the Millennial Generations in the Social Media
Authors: Ismail Ervan 
Published: December 2020

The use of the social media Instagram in Indonesia has resulted in significant impact toward the behavioural changes among the millennial generations of the nation. With regards to the statement, branding becomes a general activity that has been performed in the domain of marketing especially in today’s context. Branding might be performed in order to discern from one product of another so that the peculiar characteristics of the given product might appear to the surface. However, due to the development of the branding context, branding has penetrated many lines and this penetration also impacts the development of an individual in changing his or her behaviours within the social media alone. Therefore, throughout the study, there will be an analysis toward the formation of the celebgram’s personal branding that might alter the behaviours of the millennial generations whose identities have been prominent in the social media such as Instagram and Youtube. During the conduct of the study, the celebgram that had been analysed was Awkarin. Awkarin is a female adolescent who has suddenly become famous due to the various contents in her Instagram Account. In response to this finding, the study has been compelled to identify the personal branding of Awkawin in the Digital Public Relation of Instagram and to identify the existence of followers’ imitation toward the celebgram Awakarin in the social media Instagram. The reason is that such imitation will be peculiar existence for a celebgram who has suddenly become famous in the social media. The presence of the behavioural changes that Awkarin has pursued become a peculiar business or existence upon her individual development over the social media.
La protección de las relaciones intergeneracionales entre nietos y abuelos en el Código Civil y Comercial. Consideraciones a partir de su lectura transversal
Authors: Vazzano Florencia 
Published: December 2020

Las familias de la actualidad se desenvuelven en escenarios de múltiples interacciones intergeneracionales, es decir, vinculaciones entre sujeto/as que pertenecen a generaciones diversas (Dabove, 2008), dentro de las cuales se destacan en este trabajo las que se entablan entre nieto/as y abuelo/as, así como también, entre bisnieto/as y bisabuelo/as (Chechile-Herrera, 2012). Las relaciones intrafamiliares entre lo/as sujeto/as que integran esas generaciones reciben su debida protección en el complejo jurídico, a través de respuestas inspiradas en la protección de la “persona”, en particular, mediante un especial resguardo de los derechos de lo/as nieto/as o bisnieto/as que son niños, niñas y adolescentes (Fernández, 2015)), y abuelo/as o bisabuelo/as que son personas mayores (Dabove, 2018). El Código Civil y Comercial refleja en sus diversas captaciones la protección de las relaciones intergeneracionales entre nieto/as y abuelo/as, así como entre bisnieto/as y bisabuelo/as, integrándose al sistema jurídico en consonancia con las exigencias que devienen de los estándares internacionales y constitucionales en la materia. De allí que el presente trabajo tiene como propósito mostrar que la trascendencia que se asigna a dichas interacciones se desprende del análisis de diversos institutos incorporados al Código Civil y Comercial a partir del impacto del Derecho Internacional de los Derechos Humanos, así como de la “re-interpretación” de figuras tradicionalmente receptadas por el mundo jurídico. Por tanto, la temática se aborda desde una lectura transversal de distintas instituciones del Derecho de Familias que demuestran lo antedicho.
MEKANISME ENDOSITOSIS, DEGRADASI HEMOGLOBIN DAN DETOKSIFIKASI HEME PARASIT MALARIA
Authors: Safarianti Safarianti , Muhsin Muhsin , Maryatun Maryatun , Rezeki Soraya 
Published: December 2020

Abstrak.Parasit malaria (Plasmodium Sp) adalah parasit golongan Protozoa yang hidup obligat intrasel. Parasit ini menimbulkan penyakit malaria pada manusia melalui perantara nyamuk betina Anopheles Sp. Pada siklus hidupnya, sejumlah besar merozoit yang bebas akan menginvasi sel eritrosit host. Proses invasi ini berlangsung melalui 4 tahap yaitu attachment atau perlekatan merozoit pada permukaan eritrosit, reorientasi dengan cara berputar untuk mencari tempat yang tepat dalam memasuki sel eritrosit, lalu mengarahkan rhoptry ke permukaan eritrosit, junction dan kemudian melakukan invaginasi untuk masuk ke dalam eritrosit, diakhiri dengan sealing atau menutup kembali eritrosit.Merozoit di dalam eritrosit hidup di lingkungan yang terpisah dari suplai nutrisi sirkulasi darah, sementara parasit memerlukan nutrisi untuk pertumbuhan dan perkembangannya.Akhirnya parasit mengembangkan suatu mekanisme baru yaitu endositosis untuk mendapatkan nutrisi dari sitosol sel eritrosit host yang sebahagian besar adalah hemoglobin.Hemoglobin tersebut harus didegradasi terlebih dahulu menjadi heme dan globin agar dapat digunakan sebagai sumber asam amino bagi pertumbuhan dan perkembangan parasit. Proses degradasi hemoglobin ini menimbulkan konsekuensi yang merugikan bagi parasit karena akan membebaskan heme yang bersifat toksik, namun parasit mampu mengatasinya dengan mengembangkan beberapa cara mendetoksifikasi heme toksik menjadi pigmen hemozoin yang bersifat non toksik bagi parasit. Kata kunci : Hemoglobin, degradasi hemoglobin, detoksifikasi heme. Abstract. Malaria parasite (Plasmodium Sp) is an obligate intracellular parasit. This parasite causes malaria in humans through vector Anopheles Sp. In its life cycle, large amounts of free merozoites will invade host erythrocytes. This invasion process takes place through 4 stages, attachmentof merozoites on the surface of erythrocytes, reorientation by rotating to find the right place in entering erythrocyte cells, then directing rhoptry to surface of erythrocytes, junction and then invaginating to enter into erythrocytes, ending with sealing or closing back the erythrocytes. Merozoites in erythrocytes live in an environment separate from the supply of blood circulating nutrients, while parasites require nutrients for their growth and development. Finally the parasite develops a new mechanism called endocytosis to obtain nutrients from host erythrocytes cytosolwhich is largely are hemoglobin. The hemoglobin must first be degraded into heme and globin to be used as a source of amino acids for growth and development of parasites. This hemoglobin degradation process has an adverse consequence for the parasite because it will liberate the toxic heme, but the parasite is able to overcome it by developing some way to detoxify the toxic heme into a non-toxic crystal hemozoin. Keywords : Hemoglobin, hemoglobin degradation, heme detocxification
ANCAMAN PARTUS PREMATURUS DAPATKAH DICEGAH: SEBUAH LAPORAN KASUS DI RSUDZA BANDA ACEH
Authors: Andalas Mohd , Muchsalmina Muchsalmina , Hamle Huzaife , Ridwan Ridwan 
Published: December 2020

Abstrak. Wanita berusia 27 tahun, primigrapida, datang ke Rumah Sakit Umum Daerah dr. Zainoel Abidin (RSUDZA) dengan keluhan mules-mules dibagian perut. Pasien sudah mengeluh sejak 3 hari sebelum masuk rumah sakit. Pasien juga mengeluhkan keluar air-air dari jalan lahir. Pada pemeriksaan fisik pasien di RSUDZA dalam keadaan baik. Pemeriksaan genikologis, adneksa kiri dan kanan, tidak ada bulging pada kavum Douglas dan juga tidak ada massa didaerah serviks. Pemeriksaan laboratorium dalam batas normal. Pasien didiagnosa dengan Ancaman Partus Prematurus. Pasien direncanakan untuk mempertahankan kehamilanPada pasien ini dapat dicegah ancaman persalinan prematur dengan memberikan titrasi nifedipin 10 mg sampai hilangnya his maksimal 120 mg dan berikan maintance adalat oros 1x30mg. dan kortikosteroid untuk pematangan paru dengan deksamethason 6mg/12jam selama 2 hari, dan clindamisin 3x300 mg dan metronidazole 3x500 mg.Kasus ancaman persalinan prematur pada kasus ini bisa dicegah,sehingga dapat menurunkan resiko mortalitas dan morbilitas bagi ibu dan bayi.
ANALISIS EFEKTIVITAS BIAYA PENGGUNAAN ERITROPOETIN (HEMAPO® , EPOTREX®, NEORECORMON®) PADA PASIEN HEMODIALISIS DI RSUP PERSAHABATAN
Authors: Widianti Chandra , Anggriani Yusi , Kusumaeni Tri , Meila Okpri 
Published: December 2020

Abstrak. Penerapan INA-CBGs (Indonesia Case Base Groups) di era JKN mendorong penyedia layanan kesehatan, untuk menghitung biaya yang dikeluarkan agar tidak merugi. Pada pasien Gagal Ginjal Kronis (GGK) yang menjalani hemodialisis, prevalensi anemia cukup tinggi, sehingga diberikan eritropoetin (EPO). Dibutuhkan penelitian untuk mengetahui dari beberapa jenis EPO, mana yang lebih cost-effective. Penelitian deskriptif non-eksperimental dilakukan di Unit Hemodialisa Rumah Sakit Persahabatan. Efektivitas terapi ditentukan oleh peningkatan kadar hemoglobin (Hb) setelah 3 (tiga) bulan berturut-turut mendapatkan terapi EPO yang sama. Analisis efektivitas-biaya diperoleh dengan menghitung nilai CER (Cost-Effectiveness Ratio). Hasil menunjukkan penggunaan Neorecormon® memiliki efektivitas yang lebih tinggi dengan persentase jumlah pasien yang mengalami peningkatan Hb sebesar 56,41% dibandingkan Hemapo® (54%) dan Epotrex® (52,63%). Total biaya pengobatan rata-rata dengan Hemapo® , Epotrex® dan Neorecormon® masing-masing Rp. 32.552.117, Rp. 34.787.487 dan Rp. 32.866.969. Hasil perhitungan nilai CER dalam penggunaan Neorecormon® untuk pasien yang mengalami peningkatan Hb adalah Rp 58.264.437, lebih kecil daripada Hemapo® (Rp. 60.281.698) and Epotrex® (Rp. 66.098.208). Berdasarkan nilai CER dan tabel efektivitas-biaya, menunjukkan bahwa Neorecormon® adalah pilihan terapi yang lebih cost-effective daripada Hemapo® dan Epotrex®.Kata-kata kunci: Analisis efektivitas-biaya, hemodialisis, eritropoetinAbstract. INA-CBGs (Indonesia Case Base Groups) in JKN era, encourages health care providers to calculate costs incurred so as not to lose money. In Chronic Renal Failure (CRF) patients who undergo hemodialysis, anemia prevalence is high enough to require administration of erythropoietin (EPO). Its necessary to investigate the therapeutic treatment from several types of EPO, which is more cost-effective. Descriptive non-experimental research conducted in the Hemodialysis Unit in Persahabatan Hospital. The effectiveness determined by an increased in hemoglobin (Hb) levels after three (3) months earned the same EPO therapy. Cost-effectiveness analysis is obtained by calculated the CER (Cost-Effectiveness Ratio). The results shows that Neorecormon® have a higher effectiveness with the percentage of patients whose Hb level increase by 56.41% comparing to Hemapo® (54%) and Neorecormon® (52.63%). The average total cost with Hemapo®, Epotrex® and Neorecormon® each successive Rp. 32.552.117, Rp. 34.787.487 and Rp. 32.866.969. The CER value of Neorecormon® show cost-effectiveness of Rp 58.264.437 for a patient with an increase in Hb, smaller than Hemapo® (Rp. 60.281.698) and Epotrex® (Rp. 66.098.208). Based on CER value and cost effectiveness grid, shows that Neorecormon® is the choice that is more cost-effective than Hemapo® and Epotrex®. Keywords : Cost effectiveness analysis, hemodialysis, erythropoetin
PENATALAKSANAAN GLAUKOMA AKUT PRIMER SUDUT TERBUKA
Authors: Sari Yulia Puspita 
Published: December 2020

Abstrak. Glaukoma merupakan penyebab kebutaan kedua terbanyak di seluruh dunia setelah katarak. Glaukoma sudut terbuka primer biasanya terjadi pada pasien dewasa yaitu di atas usia 40 tahun. Laporan kasus ini memaparkan seorang pria berusia 46 tahun datang ke Poliklinik Mata Rumah Sakit Umum Daerah Dr. Zainoel Abidin Banda Aceh dengan keluhan pandangan kabur pada mata kanan. Pada pemeriksaan fisik didapatkan keadaam umum tampak sakit sedang, composmentis, TD 130/80 mmHg, Nadi 82 x/menit, RR 19 x/menit, T 36,7oC. Pemeriksaan tajam penglihatan mata kanan VOD 6/60, TIO mata kanan 21,7 mmHg dan mata kiri 17,3 mmHg. Pada pemeriksaan segmen anterior mata kanan dan kiri dalam batas normal dengan kedalaman bilik mata depan keduanya von Herick derajat II. Pada pemeriksaan gonioskopi pada mata kanan dan kiri kedua sudut bilik mata depan terbuka. Pemeriksaan perimetri dijumpai hasil yaitu pada mata kanan terdapat nasal step dan enlargement blind spot sedangkan pada mata kiri dijumpai enlargement blind spot. Pasien didiagnosa dengan glaukoma sudut terbuka primer OD. Penatalaksanaan yang dilakukan ialah dengan menggunakan obat tetes mata timolol maleat 0,5%, dan artificial tears.Kata Kunci: Glaukoma sudut primer terbuka, penatalaksanaan Abstract. Glaucoma is the second leading cause of blindness worldwide after cataracts. Primary open-angle glaucoma usually occurs in adult patients over the age of 40 years. This case report describes a 46-year-old man who came to the Eye Clinic at Dr. Zainoel Abidin Banda Aceh Regional General Hospital with complaints of blurred vision in the right eye. On physical examination showed that the general condition appeared to be moderately pain, composmentis, TD 130/80 mmHg, pulse 82 x / min, RR 19 x / min, T 36.7 ° C. Examination visual acuity of right eye was 6/60, and left eyes was 6/9. Intra ocular pressure of right eye was 21.7 mmHg and left eye was 17.3 mmHg. Anterior segment examination was normal on both eyes with anterior chamber depth was von Herick grade II of both eyes. Perimetry examination showed nasal step and enlargement of the blind spot on right eye, enlargement of the blind spot on left eye. Posterior segment examination was 0,6 with minimal cupping disc on right eye and 0,5 on left eye. This patient was diagnosed as primary open angle glaucoma OD and treated with timolol maleate 0.5% eye drops and artificial tears.Primary open angle glaucoma, managementKeywords: Primary open angle glaucoma, management
The Effect of Administration of Lycopene on Interleukin 8 Levels and Hospitalization Time of Patients with Chronic Obstructive Pulmonary Disease Exacerbations
Authors: Sutanto Yusup Subagio , Sagita Diana Kurniasari , Suradi Suradi , Kurniawan Hendra 
Published: December 2020

Background: Exacerbated chronic obstructive pulmonary disease is an acute condition, characterized by persistent air flow limitations, related to the excessive chronic inflammatory response in the airways and lung parenchyma caused by exposure to harmful gases or particles. Increased airway inflammation during exacerbations leads to increased levels of IL-8 and the risk of hospitalization. Lycopene is a carotenoid which has a positive effect on the respiratory system. The purpose of this study was to determine the effect of administration lycopene to IL-8 levels and hospitalization time of patients with COPD disease exacerbations.Methods: The experimental test with pretest and posttest design for 30 patients with COPD exacerbations in Dr. Moewardi Surakarta Hospital and Dr. Soehadi Prijonegoro Sragen Hospital was conducted from February to March 2018. Samples were taken by consecutive sampling divided into two groups including the treatment group receiving standard therapy and lycopene 1x10 mg / day during treatment and the control group only receiving standard therapy. IL-8 levels and hospitalization time of patients with COPD disease exacerbations were measured.Results: There were significant differences between the treatment group compared to the control group for a decrease in IL-8 (p = 0.029) and a decrease in hospitalization time (p = 0,000).Conclusion: The administration of lycopene 1x10 mg / day significantly reduce IL-8 levels and hospitalization time of patient with COPD exacerbations.
ORIGINAL ARTICLE: CAUSE OF STRESS AND COPING MECHANISM AMONG MEDICAL STUDENTS YEAR 2013 – 2015 IN UNIVERSITAS AIRLANGGA
Authors: Rahmi Aulia , Karimah Azimatul , Rehatta Nancy Margarita 
Published: December 2020

Abstract. Background: Stress is response and acknowledged as a natural respond to problems in daily life. Coping is defined as a process used to confront stress with various degree of effectiveness. Purpose: To correlate cause of stress and coping mechanism based on sex and year of admission among Universitas Airlangga medical students year 2013, 2014, and 2015. Method: This study was observational analytic study. Data were taken by self-administrated questionnaires (demographic, Medical Student Stressor Questionnaire, and BriefCOPE) Result: Respondents were dominated by female (60%) and out of 90 answers, the most frequent stressor was Academic Relater stressor (45.12%) regardless of the gender and admission year, and the most frequent coping mechanism is Planning (79.50%) and Religion for female students (80.75%) and 2013 students (78.75%). There was a significant correlation between stressor Intrapersonal and Interpersonal and Teaching and Learning Related also coping mechanism Planning, Humor, and Religion between male and female participants. There was also significant correlation between different admission year for coping mechanism Denial, Humor, and Self Blame. Conclusion: The most common stressor of the student year 2013, 2014, and 2015 with medical major in Universitas Airlangga is Academic Related and the most common coping mechanism is Planning.Keywords: medical student, academic stressor, coping mechanism, observational analytic study
NYERI PERUT BERULANG SAAT HAID, BERISIKO MANDUL?
Authors: Andalas Mohd , Maharani Cut Rika , Shafithri Rayhan 
Published: December 2020

Abstract. Stomach pain (dysmenorrhea) is abdominal cramps and pain during the menstrual period which can interfere with the daily activities of women of reproductive age. Dysmenorrhea is one of the symptoms that needs to be considered because it is often experienced by women and is an early sign of suffering from endometriosis. The presence of abdominal pain in women during menstruation, accompanied by pelvic pain, and infertility is a classic trias of symptoms used to diagnose endometriosis. Endometriosis occurs in almost 10% of women in the reproductive age period and more than 25-40% in infertile women. The risk of infertility is also linked because inflamed endometriosis tissue damages sperm and egg cells. Some treatments that can be done for patients with endometriosis are medical and surgical therapy. If medical therapy fails, operative laparoscopy can be alternative and hysterectomy can be considered for patients who no longer expect their reproductive function. Keywords: abdominal pain, endometriosis, infertility, dysmenorrhea. Abstrak. Nyeri Perut (dismenore) merupakan kram perut dan nyeri selama periode menstruasi yang dapat mengganggu aktivitas sehari-hari wanita usia reproduksi. Dismenore merupakan salah satu gejala yang perlu dipertimbangkan karena kerap dialami wanita dan menjadi tanda awal menderita endometriosis. Adanya nyeri perut pada wanita saat haid, disertai nyeri panggul, dan infertilitas merupakan trias klasik gejala yang digunakan untuk mendiagnosis endometriosis. Endometriosis terjadi pada hampir 10% wanita dalam kurun usia reproduksi dan lebih dari 25-40% pada wanita infertil (mandul). Risiko mandul juga dikaitkan karena jaringan endometriosis yang meradang merusak sperma dan sel telur. Beberapa pengobatan yang dapat dilakukan pada penderita endometriosis adalah terapi medikamentosa dan pembedahan. Jika terapi medikamentosa gagal, laparoskopi operatif dapat menjadi altenatif dan histerektomi dapat dipertimbangkan pada pasien yang tidak mengharapkan fungsi reproduksi lagi. Kata Kunci: nyeri perut, endometriosis, infertilitas, dismenore.