bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research and development of autism diagnosis information system based on deep convolution neural network and facial expression data
Authors: Zhao Wang , Lu Long 
Published: March 2020

PurposeFacial expression provides abundant information for social interaction, and the analysis and utilization of facial expression data are playing a huge driving role in all areas of society. Facial expression data can reflect people's mental state. In health care, the analysis and processing of facial expression data can promote the improvement of people's health. This paper introduces several important public facial expression databases and describes the process of facial expression recognition. The standard facial expression database FER2013 and CK+ were used as the main training samples. At the same time, the facial expression image data of 16 Chinese children were collected as supplementary samples. With the help of VGG19 and Resnet18 algorithm models of deep convolution neural network, this paper studies and develops an information system for the diagnosis of autism by facial expression data.Design/methodology/approachThe facial expression data of the training samples are based on the standard expression database FER2013 and CK+. FER2013 and CK+ databases are a common facial expression data set, which is suitable for the research of facial expression recognition. On the basis of FER2013 and CK+ facial expression database, this paper uses the machine learning model support vector machine (SVM) and deep convolution neural network model CNN, VGG19 and Resnet18 to complete the facial expression recognition.FindingsIn this study, ten normal children and ten autistic patients were recruited to test the accuracy of the information system and the diagnostic effect of autism. After testing, the accuracy rate of facial expression recognition is 81.4 percent. This information system can easily identify autistic children. The feasibility of recognizing autism through facial expression is verified.Research limitations/implicationsThe CK+ facial expression database contains some adult facial expression images. In order to improve the accuracy of facial expression recognition for children, more facial expression data of children will be collected as training samples. Therefore, the recognition rate of the information system will be further improved.Originality/valueThis research uses facial expression data and the latest artificial intelligence technology, which is advanced in technology. The diagnostic accuracy of autism is higher than that of traditional systems, so this study is innovative. Research topics come from the actual needs of doctors, and the contents and methods of research have been discussed with doctors many times. The system can diagnose autism as early as possible, promote the early treatment and rehabilitation of patients, and then reduce the economic and mental burden of patients. Therefore, this information system has good social benefits and application value.
Sustainability reporting and performance of MENA banks: is there a trade-off?
Authors: Buallay Amina , Fadel Sayed M. , Al-Ajmi Jasim Yusuf , Saudagaran Shahrokh 
Published: March 2020

PurposeSustainability reporting has been widely adopted by firms worldwide given stakeholders’ need for more transparency on environmental, social and governance (ESG) issues. This study aims to investigate the relationship between ESG and bank’s operational (return on assets [ROA]), financial (return on equity [ROE]) and market performance (Tobin’s Q) in a group of emerging countries in the Middle East and North Africa (MENA) region.Design/methodology/approachThis study examines 59 banks listed on the stock exchanges of MENA countries over a period of 10 years (2008-2017). Only conventional banks with all data for at least two years are included in the sample. The core independent variable is ESG scores, and the dependent variables are ROA, ROE and Tobin’s Q. This study uses bank- and country-specific control variables to measure the relationship between sustainability reporting and bank’s performance.FindingsThe findings from the empirical results demonstrate a significant positive impact of ESG on performance and economic benefits to shareholders. However, the relationship between ESG disclosures varies individually; unlike the majority of published research, the authors found that social performance plays a negative role in determining bank’s profitability and value. Furthermore, the authors present evidence in support of the impact of bank- and country-specific factors in determining bank’s performance.Originality/valueTo the best of the authors’ knowledge, this is the first study to investigate the impact of sustainability reporting on banks’ performance in the MENA region. It provides evidence that questions the positive relationship between sustainability reporting and financial measures of performance.
Properties of glass/epoxy sandwich structure for electronic boards
Authors: Pietrikova Alena , Lenger Tomas , Fricova Olga , Popovic Lubos , Livovsky Lubomir 
Published: March 2020

Purpose
This study aims to characterize a novel glass/epoxy architecture sandwich structure for electronic boards. Understanding the thermo-mechanical behavior of these composites is important because it is possible to pre-determine whether defined “internal” thick laminates will be suitable for embedding components in the direction of the axis “z,” i.e. this method of manufacturing multilayer laminates can be used for incoming miniaturization in electronics.

Design/methodology/approach
Laminates with a low glass transition temperature (Tg) and high Tg with E-glass type were treated, tested and compared. Testing samples were manufactured by nonstandard two steps unidirectional lamination as a multilayer structure based on prepreg layers and as “a sandwich structure” to explore its effect on thermo-mechanical properties. The proposed tested method determines the time and temperature-dependent viscoelastic properties of the board by using dynamic mechanical analysis, thermo-mechanical analysis and three-point bend tests.

Findings
This testing method was chosen because the main property that promotes sandwich structure is their high stiffness. Glass/epoxy stiff and thermal stabile sandwich structure prepared by nonstandard two-stage lamination is proper for embedding components and the next miniaturization in electronics.

Originality/value
Compared with by-default applied glass-reinforced homogenous laminates, novel architecture sandwich structure is attractive because of a combination of strength, stiffness and all while maintaining the miniaturization requirement and multifunctional application in electronics.
Chasing productivity demands, worker well-being, and firm performance
Authors: Ab Wahab Mastura , Tatoglu Ekrem 
Published: March 2020

PurposeThis study aims to examine the impact of chasing productivity demands on worker well-being and firm performance in manufacturing firms in Malaysia. Flexible work arrangements and human resources support are used as moderators to mitigate the adverse impacts associated with chasing productivity demands.Design/methodology/approachData were collected from 213 workers from manufacturing firms through a survey questionnaire utilizing structural equation modeling.FindingsThe findings of the study show that flexible work arrangements play a significant role in moderating the relationship between chasing productivity demands and well-being, and between chasing productivity demands and firm performance. The study also shows that flexible work arrangements are important to buffer the adverse effects of chasing productivity demands on worker well-being. In addition, flexible work arrangements strengthen the positive effect of worker well-being on firm performance.Research limitations/implicationsThis study highlights the importance of flexible work arrangements in overcoming the negative impact of the relationship between chasing productivity demands and worker well-being and strengthening the positive impact of the relationship between worker well-being and firm performance.Originality/valueThis study has extended the variable of chasing productivity demands in the existing literature on the job demands–job control model, specifically in manufacturing firms.
Vulnerable minds, bodily thoughts, and sensory spirits: local theory of mind and spiritual experience in Ghana
Authors: Dulin John 
Published: March 2020

AbstractThis essay looks at the resonances between common cultural models of the mind in the central region of Ghana and patterns of spiritual experience among charismatic evangelical Christians and practitioners of southern Ghana's indigenous religion, known as traditionalists. In particular, I examine the resonance between the model of the mind that construes it as porous, as vulnerable to forcible take‐over by hostile entities, and experiences of divine beings insistently pushing people to do their will. It is also relatively common for people in Ghana to report seeing the divine with their eyes and hearing it with their ears. I argue that this experience resonates with, and is perhaps facilitated by, a tendency of local models of mind in Ghana to blend sense and percept.
Unpopular Sovereignty?
Authors: Somek Alexander , Wilkinson Michael A. 
Published: March 2020

AbstractPopular sovereignty was presented in modern constitutional discourse as a mode of collective action. It was supposedly manifest in the power to constitute, control and dismantle governments. Important strands of contemporary constitutional theory, notably legal constitutionalism and deliberative democracy, have taken leave of this tradition. They have severed the connection between sovereignty and action. What remains of popular sovereignty is fundamental rights and values, or dispersed networks of deliberation. This is based on the the idea that the place of power is ‘empty’ and legitimised on the principle of including ‘All‐Affected‐Interests’. The very concept of sovereignty thus becomes unpopular. This contribution aims to re‐establish the link between popular sovereignty and action by examining sovereignty's emancipatory telos, its majoritarian mode of operation and its dependence on political citizenship.
Metabolic modulation of redox state confounds fish survival against Vibrio alginolyticus infection
Authors: Gong Qi‐yang , Yang Man‐jun , Yang Li-fen , Chen Zhuang‐gui , Jiang Ming , Peng Bo 
Published: March 2020

SummaryVibrio alginolyticus threatens both humans and marine animals, but hosts respond to V. alginolyticus infection is not fully understood. Here, functional metabolomics was adopted to investigate the metabolic differences between the dying and surviving zebrafish upon V. alginolyticus infection. Tryptophan was identified as the most crucial metabolite, whose abundance was decreased in the dying group but increased in the survival group as compared to control group without infection. Concurrently, the dying zebrafish displayed excessive immune response and produced higher level of reactive oxygen species (ROS). Interestingly, exogenous tryptophan reverted dying rate through metabolome re‐programming, thereby enhancing the survival from V. alginolyticus infection. It is preceded by the following mechanism: tryptophan fluxed into the glycolysis and tricarboxylic acid cycle (TCA cycle), promoted adenosine triphosphate (ATP) production and further increased the generation of NADPH. Meanwhile, tryptophan decreased NADPH oxidation. These together ameliorate ROS, key molecules in excessive immune response. This is further supported by the event that the inhibition of pyruvate metabolism and TCA cycle by inhibitors decreased D. reiro survival. Thus, our data indicate that tryptophan is a key metabolite for the host to fight against V. alginolyticus infection, representing an alternative strategy to treat bacterial infection in an antibiotic‐independent way.
Myriocin‐induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition and heat tolerance
Authors: Randez‐Gil Francisca , Prieto Jose A. , Rodríguez‐Puchades Alejandro , Casas Josefina , Sentandreu Vicente , Estruch Francisco 
Published: March 2020

SummaryThe modification of lipid composition allows cells to adjust membrane biophysical properties in response to changes in environmental temperature. Here, we use adaptive laboratory evolution (ALE) in the presence of myriocin, a sphingolipid (SLs) biosynthesis inhibitor, to remodel the lipid profile of an industrial yeast strain (LH) of Saccharomyces cerevisiae. The approach enabled to obtain a heterogeneous population (LHev) of myriocin‐tolerant evolved clones characterized by its growth capacity at high temperature. Myriocin exposure also caused tolerance to soraphen A, an inhibitor of the acetyl‐CoA carboxylase Acc1, the rate‐limiting enzyme in fatty acid de novo production, supporting a change in lipid metabolism during ALE. In line with this, characterization of two randomly selected clones, LH03 and LH09, showed the presence of lipids with increased saturation degree and reduced acyl length. In addition, the clone LH03, which displays the greater improvement in fitness at 40°C, exhibited higher SL content as compared with the parental strain. Analysis of the LH03 and LH09 genomes revealed a loss of chromosomes affecting genes that have a role in fatty acid synthesis and elongation. The link between ploidy level and growth at high temperature was further supported by the analysis of a fully isogenic set of yeast strains with ploidy between 1N and 4N which showed that the loss of genome content provides heat tolerance. Consistent with this, a thermotolerant evolved population (LH40°) generated from the parental LH strain by heat‐driven ALE exhibited a reduction in the chromosome copy number. Thus, our results identify myriocin‐driven evolution as a powerful approach to investigate the mechanisms of acquired thermotolerance and to generate improved strains.
Improvement of homologous GH10 xylanase production by deletion of genes with predicted function in the Aspergillus nidulans secretion pathway
Authors: Zubieta Mariane P. , Gerhardt Jaqueline A. , Rubio Marcelo V. , Terrasan César R. F. , Persinoti Gabriela F. , Antoniel Everton P. , Contesini Fabiano J. , Prade Rolf A. , Damasio André 
Published: March 2020

SummaryFilamentous fungi are important cell factories for large‐scale enzyme production. However, production levels are often low, and this limitation has stimulated research focusing on the manipulation of genes with predicted function in the protein secretory pathway. This pathway is the major route for the delivery of proteins to the cell exterior, and a positive relationship between the production of recombinant enzymes and the unfolded protein response (UPR) pathway has been observed. In this study, Aspergillus nidulans was exposed to UPR‐inducing chemicals and differentially expressed genes were identified by RNA‐seq. Twelve target genes were deleted in A. nidulans recombinant strains producing homologous and heterologous GH10 xylanases. The knockout of pbnA (glycosyltransferase), ydjA (Hsp40 co‐chaperone), trxA (thioredoxin) and cypA (cyclophilin) improved the production of the homologous xylanase by 78, 171, 105 and 125% respectively. Interestingly, these deletions decreased the overall protein secretion, suggesting that the production of the homologous xylanase was specifically altered. However, the production of the heterologous xylanase and the secretion of total proteins were not altered by deleting the same genes. Considering the results, this approach demonstrated the possibility of rationally increase the production of a homologous enzyme, indicating that trxA, cypA, ydjA and pbnA are involved in protein production by A. nidulans.
Primary lung squamous cell carcinoma and its association with gastric metastasis: A case report and literature review
Authors: Nemoto Mariko , Prasoon Pankaj , Ichikawa Hiroshi , Hanyu Takaaki , Kano Yosuke , Muneoka Yusuke , Usui Kenji , Hirose Yuki , Miura Kohei , Shimada Yoshifumi , Nagahashi Masayuki , Sakata Jun , Ishikawa Takashi , Tsuchida Masanori , Wakai Toshifumi 
Published: March 2020

AbstractNearly 50% of primary lung carcinoma patients present with distant metastasis at their first visit. However, gastrointestinal tract (GIT) metastasis is an infrequent impediment. Herein, we report a case of progressive dysphagia and epigastralgia as an initial manifestation of recurrence as gastric metastasis of primary lung squamous cell carcinoma (SCC) after curative surgery. A 64‐year‐old man was diagnosed with primary lung SCC of the right lower lobe, and underwent thoracoscopic lower lobectomy. One year after lobectomy, computed tomography (CT) scan showed a gastric fundal mass located in the gastric cardia which measured 5 cm. Endoscopic biopsies and histopathology subsequently confirmed that tumor was SCC. The patient then underwent proximal gastrectomy with resection of the diaphragmatic crus. Following surgery, histopathological examination revealed gastric metastasis from primary lung SCC.Key pointsGastric metastasis of primary lung carcinoma is one of the rarest phenomena. Gastrointestinal symptoms should raise suspicion of the presence of advanced metastatic disease with poor prognosis.
N‐acetylcysteine reduces cocaine‐seeking behavior and anterior cingulate glutamate/glutamine levels among cocaine‐dependent individuals
Authors: Woodcock Eric A. , Lundahl Leslie H. , Khatib Dalal , Stanley Jeffrey A. , Greenwald Mark K. 
Published: March 2020

AbstractN‐acetylcysteine (NAC) is a cystine prodrug shown to reduce cocaine‐ and cue‐primed reinstatement of cocaine‐seeking behavior in preclinical studies. In this inpatient study, the effects of NAC maintenance versus placebo on cocaine‐seeking behavior were examined during cocaine‐primed and unprimed self‐administration sessions among non‐treatment‐seeking, cocaine‐dependent individuals. Twelve participants completed this double‐blind, placebo‐controlled, within‐subject crossover study. Each participant was maintained for 1 week (Sat–Fri) on NAC (1200‐mg TID; 3600 mg/day total) and 1 week on placebo (0‐mg TID); medication order was randomized. A subset of participants underwent proton magnetic resonance spectroscopy scans (n = 8) on the third day of medication (Mon) to assess neurochemistry in the rostral anterior cingulate (rACC; voxel = 4.5 cm3). In four randomized sessions (Tue–Fri) each week, each participant could earn unit amounts of cocaine (10 mg, fixed) versus money ($0.50 vs. $1.50) on a choice, progressive ratio schedule after insufflating active versus placebo cocaine‐priming doses (110 mg vs. 4 mg). Relative to the placebo priming dose, the active cocaine priming dose (110 mg) increased cocaine‐seeking behavior (p = .003). NAC reduced cocaine‐primed cocaine‐seeking behavior compared with placebo levels (p = .044) but did not alter placebo‐primed cocaine‐seeking behavior. The larger money alternative ($1.50) suppressed cocaine‐seeking behavior relative to the smaller money alternative ($0.50; p = .011). Compared with placebo levels, NAC significantly decreased rACC glutamate + glutamine levels (p = .035) and numerically decreased rACC glutamate levels (p = .085). These preliminary findings indicate that NAC suppresses cocaine‐seeking behavior in some, but not all, experimental scenarios. Further, our findings suggest NAC may exert its therapeutic effects by modulating excitatory tone in the rACC.
Bank ownership type and temporal evolution of long‐term bank funding in the period 2005–2017
Authors: Meriläinen Jari‐Mikko 
Published: March 2020

AbstractThis study uses a large panel dataset of Western European banks to examine the determinants of bank funding stability. Banks are divided into three categories by bank ownership type; the ownership types in this study are commercial banks, cooperative banks and savings banks. Three sources of stable bank funding are investigated: customer deposits, equity, and long‐term liabilities. Furthermore, the sum of these funding components is used as a proxy variable for a bank's total available stable funding (ASF). A special focus is on the temporal evolution of these funding types. The regression results show that commercial banks’ funding became much more stable in the period 2005–2017. However, that funding remains, on average, less stable than does cooperative and savings banks’ funding. In addition, funding stability has remained at the pre‐crisis level in cooperative and savings banks, despite a steep dip in cooperative banks’ ASF during the sovereign debt crisis. Furthermore, banks substantially decreased financing from long‐term liabilities after the financial crisis, replacing it with customer deposits and equity.
Dentists’ perspectives on barriers to providing oral health care in French psychiatric hospitals with on‐site dental clinics
Authors: Couatarmanach Antoine , Sherlaw William , Prigent Pierre‐Marie , Harpet Cyrille , Bertaud Valérie 
Published: March 2020

AbstractObjectivesPsychiatric inpatients suffer from poorer oral health than the general population, and difficulties in accessing necessary dental treatment remain even when a dedicated dental service is available within the psychiatric hospital. The aim of this study was to identify barriers to access dental care from the point of view of dentists working within French psychiatric hospitals.MethodsThe relatively small number of dentists working in psychiatric hospitals necessitated a qualitative approach. Semi‐structured interviews were conducted, recorded, transcribed and coded in a conventional content analysis approach.ResultsEight interviews were conducted. Six of the dentists interviewed were men, and two were women. Three of them worked full‐time in a psychiatric facility, while the other five worked partly in the hospital and partly in private practice. The average duration for interviews was 54 minutes (minimum 24 min, maximum 89 min). The interviews highlighted three dimensions of barriers to access to dental care. The first dimension was directly related to the patient. This may be linked to the patient's psychiatric disorder but not necessarily. This also encompasses refusal of care. A second dimension regrouped events related to the organization of the hospital (locally), such as communication issues between staff members within the dental office, and with other staff members from the psychiatric ward. A third dimension included difficulties related to the overall organization of the healthcare system, including financial issues and deinstitutionalization.ConclusionsIn‐site dental consultations appear as an interesting tool to enhance access to oral care for psychiatric inpatients. However, difficulties remain from the dentists' perspective.