bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proteomic and Metabolomic Analyses of the Inflorescences Axis of Castor (Ricinus conununis L.) at Different Developmental Stages
Authors: Zhao Yong , Peng Mu , Chang Ruhui , Zhu Guoli , He Zhibiao , Li Guorui , Di Jianjun , Li Lili , Zhao Huibo , Wen Qi , Liang Xiaotian , Meng Fanjuan , Huang Fenglan 
Published: August 2020

Abstract
Background: Castor is a dicotyledon, ricinus communis, Euphorbiaceae, and is oneof world ten oil crops. Lm female line castor has three inflorescence types(female with marker, haplometrotic and monoecious). Female with marker castor was realized as a restorer line and as a maintainer line,which was applied to castor hybrid breeding. The developmental mechanism of the three inflorescences is not clear.Results: Therefor, in this study , proteomic and metabolomic analyses of different inflorescences axis were performed. Seventy-three diferentially abundant protein species (DAPS) were detected in the proteomics analysis and 86 differentially abundant metabolites (DAMs) were identified from the proteomic and metabolomic analyses of the inflorescences axis, respectively. These DAPS and DAMs are primarily mainly involved in carbon metabolism, comprising carbon fixation in the photosynthetic organism pathway, the glycolysis pathway, carbon metabolic pathways, and the biosynthesis of amino acids. Quantitative real-time PCR (qRT-PCR) results demonstrated that the proteomics and metabolomic data collected in this study were reliable.Conclusions: The results of this study provides some valuable insights into the inflorescence development of castor: Specifically, the results showed that DAPS and DAMs are involved in photosynthesis and respiration to control the distribution of imported carbohydrates and exported photoassimilates and thus affect inflorescence development of castor. Furthermore, the dynamic balance of amino acids in different types of inflorescences was also shown to be essential in affecting inflorescence structure.
Does Mindfulness Training Affect Rumination in Women with Breast Cancer?
Authors: Bagherzadeh Razieh , Sohrabinezhad Rezvan , Gharibi Tayebeh , Mehbodi Farkhondeh , Vahedparast Hakimeh 
Published: August 2020

Abstract
Background: Cancers cause not only physical and social impairments but also psychological stress responses such as rumination, which require more attention from researchers as well as clinicians.Aim: This study aimed to investigate the effect of mindfulness training on rumination in women with breast cancer.Method: This randomized controlled trial was performed on 46 women with breast cancer in Bushehr city (2018). Subjects were randomly assigned to two intervention and control groups. The intervention was 8 sessions of group mindfulness training. A rumination questionnaire was administered before the intervention, immediately, and one month after the intervention. The data were analyzed by analytical tests at the 0.05 significance level.Results: There was no significant difference between the rumination scores of the intervention group at the three stages of measurement. For the control group, the mean rumination scores at the posttest and follow-up stages were both significantly higher than the pretest score (P <0.001). Also, the follow-up mean rumination score of the control group was significantly higher than that posttest (P=0.02). Comparison of the two groups where adjusted for baseline, showed a significant difference between the two groups in terms of mean rumination score at the posttest stage (P=0.01) and at the follow-up stage (P<0.001).Conclusion: Subjects in the intervention group were more successful in avoiding increasing rumination than those in the control group, an ability that must be attributed to the effect of mindfulness training. Still, further research is needed to determine whether longer interventions will be able to reduce rumination.Trial registrationTrial registration number: IRCT20090522001930N2 Date: 2018-08-08
Patients’ Perceptions and Satisfaction Regarding Teleconsultations During the COVID-19 Pandemic in Jeddah, Saudi Arabia
Authors: Magadmi Mawadah M , Kamel Fatemah O , Magadmi Rania M 
Published: August 2020

Abstract
Background: The coronavirus disease 2019 (COVID-19) pandemic has resulted in the widespread implementation of teleconsultation. Teleconsultation provides remote communication and reduces the risk of virus transmission. However, patients’ perceptions and satisfaction are relevant to ensuring the quality of the service. Thus, this study aimed to evaluate patients’ perceptions and satisfaction regarding teleconsultations during the COVID-19 pandemic in Jeddah.Methods: This was a cross-sectional study using an electronic questionnaire to assess patients’ perceptions and satisfaction regarding teleconsultations during May 2020. A total of 407 participants were included.Results: Most (38.6%) participants were aged 40 to 59 years, women (73.2%), and had a university education (70.8%). Patients’ perceptions of the effectiveness of teleconsultation ranged from 71.43% to 88.77% and their satisfaction level ranged between 59.40% and 83.96%. Older patients who had favorable outcomes from teleconsultation strongly agreed about the effectiveness of teleconsultation and were more satisfied. Patients with higher education levels who used the service only once were more satisfied with the experience. Moreover, those patients with greater age and educational levels and those who called for emergencies and to request medication refills were more likely to use teleconsultation in the future beyond the COVID-19 pandemic. When asked about reasons for dissatisfaction, 70% of the participants were unhappy with the wait time for a teleconsultation.Conclusions: Most patients were satisfied with the teleconsultations during the COVID-19 pandemic. However, a better understanding of patients’ perceptions and reasons for dissatisfaction are fundamental in the planning and implementation of teleconsultations in Saudi Arabia.
Modeling soil organic carbon as a function of topography and forest characteristics
Authors: Malla Rajesh , Neupane Prem Raj , Köhl Michael 
Published: August 2020

Abstract
BackgroundThe soil organic carbon (SOC), an important carbon pool among the five forest carbon pools, plays a crucial role in global carbon cycling. However, it is affected by various factors like topography and climate. Some studies conducted for smaller areas have shown a dependence of the SOC on altitude, but do not allow a general statement for larger regions. Nepal, which has the world's most dynamic terrain elevation, is ideally suited for studying the dependence of the SOC on altitude. ResultsWe found a significant correlation between SOC and altitude (r=0.81). In our study, altitude alone can explain about 66 percent of the variability of the SOC. On the basis of our data, we developed a model which, with altitude as the only independent variable, can predict around 61 percent of the SOC. Conclusions﻿Only altitude has been found to be a sound predictor of SOC at the national level. Other factors with potential impacts on SOC predictors such as crown cover, slope or basal area have only a minor contribution to the improvement of prediction accuracy of the model.
Identification of Ubiquitin Ligase From Grapevine Ring C3H2C3E3 and Characterization of Drought Resistance Function of VyRCHC114
Authors: Yu Yihe , Yang Shengdi , Bian Lu , Yu Keke , Meng Xiangxuan , Zhang Guohai , Xu Weirong , Yao Wenkong , Guo Dalong 
Published: August 2020

Abstract
Background: RING is one of the largest E3 ubiquitin ligase families and C3H2C3 type is the largest subfamily of RING, playing an important role in plants’ development and growth and their biotic and abiotic stress responses. Results: A total of 143 RING C3H2C3-type genes (RCHCs) were discovered from the grapevine genome and separated into groups (I-XI) according to their phylogenetic analysis, with these genes named according to their positions on chromosomes. Gene replication analysis showed that tandem duplications play a predominant role in the expansion of VyRCHCs family together. Structural analysis showed that most VyRCHCs(67.13%) had no more than 2 introns, while genes clustered together based on phylogenetic trees had similar motifs and evolutionarily conserved structures. Cis-acting element analysis showed the diversity of VyRCHCs regulation. The expression profiles of eight DEGs in RNA-Seq after drought stress were similar to those in qRT-PCR analysis. The in vitro ubiquitin experiment showed that VyRCHC114 had E3 ubiquitin ligase activity, overexpression of VyRCHC114 in Arabidopsis improved drought tolerance, moreover, the transgenic plant survival rate increased by 30%, accompanied by changing of electrolyte leakage, chlorophyll content and the activities of SOD, POD, APX and CAT were changed. AtCOR15a, AtRD29A, AtERD15 and AtP5CS1 were expressed quantitatively, the results showed that they participated in the drought stress response may be regulated by the expression of VyRCHC114.Conclusions: Valuable new information on the evolution of grapevine RCHCs and its relevance for studying the functional characteristics of grapevine VyRCHC114 genes under drought stress emerged from this research.
Role of MADS-box Gene in the Development of Flower Organs in Pineapple of a Typical Collective Fruit
Authors: zhang hongna , Pan Xiaolu , Yi Debao , Lin Wenqiu , Zhang Xiumei 
Published: August 2020

Abstract
Background: MADS-box genes play crucial roles in plant vegetative and reproductive growth, especially in inflorescences, flower, and fruit. Pineapple is a typical collective fruit, and a comprehensive analysis of the MADS-box gene family in the development of floral organs of pineapple is still lacking. Results: In this study, the whole-genome survey and expression profiling of the MADS-box family in pineapple were introduced. Forty-four AcMADS genes were identified in pineapple, 39 of them were located on 18 chromosomes and five genes were distributed in five scaffolds. Twenty-two AcMADS genes were defined as 15 pairs of segmental duplication events. Syntenic analysis showed that pineapple is closely related to monocotyledon plants. Most members of the type II subfamily of AcMADS genes had higher expression levels in floral organs compared with type I subfamily, thereby suggesting that AcMADS of type II may play more crucial roles in the development of floral organs of pineapple. Six AcMADS genes have significant tissue-specificity expression, thereby suggesting that they may participate in the formation of one or more floral organs. Conclusions: Our findings not only benefit to reveal the functional characterization of MADS-box genes in the floral organ development of pineapple but also provide additional information for further understanding the formation and development collective fruit.
The Impact and Response to Climate-Related Disasters in Burkina-Faso
Authors: Zerbo Alexandre , Delgado Rafael Castro , González Pedro Arcos 
Published: August 2020

Abstract
Burkina Faso is a West African Sahelian country with climate-related risks because the disaster risk profile, and drought and floods are the main damaging natural disasters, aggravated by the phenomenon of climate change. An effective design and implementation of disaster reduction management strategies requires an understanding of risk factors and vulnerabilities, but also and an assessment of the strengths and weaknesses of national disaster response systems.In this perspective, a literature review and an analysis of climate information were conducted in order to reveal the risks and vulnerabilities to droughts and floods in the country. This was accompanied by a critical evaluation of the performance of the national prevention and intervention system.Vulnerabilities to drought and floods are exacerbated by the combined effect of climate change and the low performance of the national disaster risk reduction management system. National institutions and frameworks exist for disaster prevention and management, but difficulties persist in implementation due to financial constraints and insufficient human skills. Current trends and estimates suggest that the drawbacks of these natural hazards may be more serious in the future if solutions are not taken to improve early warning forecasts, infrastructure and the implementation of adequate agricultural policies.
The "Glass Lung" - A Lifelike Electromechanical Lung Simulator
Authors: Peuscher Heiko , Dubies Karl , Blechschmidt Ronald , Calzia Enrico , Radermacher Peter 
Published: August 2020

Abstract
Background: This contribution describes the hardware setup, control, andparametrization of an electromechanical test lung intended to perform tests withclinical ventilators.Methods: We use a nonlinear model to imitate the dynamic behavior of a reallung in terms of compliance and resistance. Both passive behavior andspontaneous breathing (weaning) are supported. In automated test sequences,the test lung mimics a variety of physiological and pathological lung conditions,including COVID-19.Results: We present the results obtained with an approved clinical ventilator invarious modes including pressure-controlled and pressure support ventilation.Conclusions: All results are clinically consistent with the values expected fromventilation of a real patient.
Evaluation the energy production potential of aggressively invasive Prosopis juliflora Sw (Fabacea): An emerging threat in the Bundala Ramsar Wetland
Authors: Bandara W.A.R.T.W. , Ranasinghe Oshadi Ruwanthika , Vlosky Richard 
Published: August 2020

Abstract
Prosopis juliflora is an invasive plant species rapidly expanding in the Asian and African continents. Invasion of P. juliflora in Bundala Ramsar Wetland (BRW) in Sri Lanka has created a number of biodiversity and conservation issues. This study was conducted to assess the possibility to utilize this invasive plant as a fuel source for local industries. The moisture content, wood density, ash content, volatile matter, fixed carbon content, biomass/ash ration and calorific value of P. juliflora were measured and compared with Leucaena leucocephala, which is a widely used fuelwood source in Sri Lanka and elsewhere. P. juliflora, performed better than L. leucocephala for most of these parameters. Ash content was comparatively higher in P. juliflora than that of L. leucocephala; however, biomass to ash ratio of P. juliflora was significantly lower (at 0.05 level of significance) than that of L. leucocephala, suggesting its suitability as a fuelwood source. Further, the Fuel Value Index (FVI) of P. juliflora (3,276) was slightly lower than that of L. leucocephala (3,336), a non-significant difference. P. juliflora and L. leucocephala reached Fiber Saturation Point values within drying periods of 24 and 27 days, respectively. According to our estimates of energy properties, 1 Kg of P. juliflora could be used to substitute 0.5 L of diesel and furnace oil as well as 5 kWh (5 units) of electricity. As such, we recommend harvesting P. juliflora from BRW as a potential fuelwood energy source for local industries.
Effectiveness of High-Flow Nasal Cannula on Pulmonary Rehabilitation in Subjects with Chronic Respiratory Failure
Authors: Chihara Yuichi , Tsuboi Tomomasa , Sumi Kensuke , Sato Atsuo 
Published: August 2020

Abstract
Backgrounds: There are no clinical data comparing the effect of exercise training using both high fraction of inspired oxygen (FIO2) and high flow through a high-flow nasal cannula (HFNC) with that of ordinary supplemental oxygen on exercise capacity in subjects with chronic respiratory failure (CRF) receiving long-term oxygen therapy (LTOT). Methods: In this randomized study, 32 patients with CRF receiving LTOT were assigned to undergo 4 weeks of exercise training on a cycle ergometer using an HFNC (flow: 50 L/min) with a FIO2 of 1.0 (HFNC group; n=16) or ordinary supplemental oxygen via a nasal cannula (flow: 6 L/min) (oxygen group; n=16). Before and after 4 weeks of exercise training, a 6-min walking test, constant-load test, and blood sampling were performed. Results: Prior to exercise training, the endurance time of the constant-load exercise test using an HFNC was significantly longer than that reported with prescribed oxygen in daily LTOT (p=0.004) or a 6 L/min nasal cannula (p=0.0003). Following 4 weeks of exercise training, change in the 6-min walking distance was significantly greater in the HFNC versus the oxygen group (55.2±69.6 m vs. —0.5±87.3 m, respectively; p=0.04). The plasma levels of adrenaline, noradrenaline, and serum C-reactive protein were significantly decreased only in the HFNC group, after 4 weeks of exercise training. Conclusions: Despite heterogeneity in the effect among patients, exercise training using both high FIO2 and high flow through an HFNC is a potentially superior exercise training modality for CRF patients receiving LTOT.Clinical Trial Registration ― http://www.clinicaltrials.gov. Unique identifier:　NCT02804243. Registered 13 June 2016.
Storm Surge Hazard Assessment Along the East Coast of India Using Geospatial Techniques
Authors: Prince Harshith C. , Nirmala R. , Mahendra R. S. , Murty P.L. N. 
Published: August 2020

Abstract
The present study is to estimate the inundation extent and depth to estimate the extent of damage using geospatial technique caused due to a storm surge. This is achieved by selecting a worst-case cyclone track (Super Cyclonic Storm) scenario for three Indian states, Andhra Pradesh, Odisha and West Bengal based on the historic data. Over 1300 cyclones are observed to have hit the east coast of India in the past 173 years, which is about an average of more than 7 cyclones per year. Geospatial model results for Orissa cyclone (1999) suggests that over 2,150 km2 of land is submerged due to storm surge. The inundation was observed up to an extent of 45 km inland upright to the shoreline with over 1,100 km2 area submerged 1-2m from ground level. This is the worst cyclone (with peak speed 140 knots) of the country known so far to have caused maximum damage. The storm surge model of Andhra cyclone (1996) suggests that about 450 km2 of area inundated due to storm surge where majority of the area is submerged up to1m of water pile. The most affected place is Mummidavaram. Whereas, the results of storm surge model for the state of West Bengal is carried out using a synthetic track passing through West Bengal coast with wind speed of 155 knots (worst case). The model result shows 5,400 km2 of land submerged up to 1m of water and about 2,700 km2 of area submerged under 1-2m of water. The most affected area is South 24 Parganas and parts of Bangladesh. The results of the current study are useful for the coastal cyclone disaster management in order to make decisions on preparedness and disaster risk reduction. These results can also be used for the coastal future development purposes.
High values of liver stiffness play an important role in stratifying the risk of hepatocellular carcinoma in cirrhotic hepatitis C patients.
Authors: Paranagua-Vezozzo Denise , Reinoso-Pereira Gleicy Luz , Mazo Daniel F. , Nacif Lucas Souto , Moutinho Bruna Damasio , Moutinho Renata , Ono Suzane Kioko , França João Italo Dias , Alves Venâncio Avancini Ferreira , Carrilho Flair José 
Published: August 2020

Abstract
Background: The identification and selection of patients at-risk for HCC is a recognized challenge in outpatient clinical practice. Limited data on risk factors and the impact of HCC on cirrhotic patients stratified by the elasticity imaging technique are still a potential promise. Aim: To evaluate the clinical contribution of liver stiffness measurement by transient elastography, as a risk factor for Hepatocellular Carcinoma (HCC) occurrence in a prospective cohort of (HCV) patients with cirrhosis. Method: A cohort of 99 consecutive HCV patients was included between 2011 and 2016 with baseline liver stiffness equal or above 12 kPa. We evaluated the patients with serum and mechanical liver tests. Kaplan-Meier method with the log-rank test and the use of Cox Univariate and multivariate analysis assessed the association between variables and clinical results. Results: The mean age was 57.8±10.6 years. In a follow-up over a mean of 3.3 years, 20 (20.2%) patients developed HCC, of which 65% were male and 40% had diabetes. The median time to diagnosis of HCC was 2.6 years. In univariate logistic regression analysis, variables associated with HCC occurrence were: lower platelet count (p=0.0446), higher serum alpha-fetoprotein (p=0.0041) and bilirubin (p=0.0008) values, higher MELD score (p=0.0068) and higher liver stiffness measurement (p=0.0354). High LSM evaluated by TE was independently associated with HCC development, and the best cut-off value for HCC risk was > 21.1kPa (HR: 4.7695; 95%CI: 1.0470-21.7274; p=0.0435). Conclusion: High value of liver stiffness relates substantially to the increased risk for HCC in selected patients with HCV cirrhosis.
Metagenomic Analysis of the Gut Microbiome in Psoriasis Reveals Three Subgroups with Distinct Host-Microbe Interactions
Authors: Chang Hsin-Wen , Yan Di , Singh Rasnik , Bui Audrey , Lee Kristina , Truong Alexa , Milush Jeffrey M , Somsouk Ma , Liao Wilson 
Published: August 2020

Abstract
Background

Psoriasis is a chronic, inflammatory skin disease that impacts 2–3% of the global population. Besides skin manifestations, psoriasis patients have increased susceptibility to a number of comorbidities including psoriatic arthritis, cardiovascular disease, and inflammatory bowel disease. To understand the systemic component of psoriasis pathogenesis, we examined the fecal metagenome, host colonic transcriptome, and host peripheral blood immune profiles of psoriasis patients and healthy controls.
Results

Our analysis showed increased functional diversity in the gut microbiome of psoriasis patients. In addition, we identified microbial species that preferentially associate with psoriasis patients and which have been previously found to associate with other autoimmune diseases. Intriguingly, our data reveal new insights about psoriasis disease heterogeneity, as we identified three psoriasis subgroups that have distinct microbial and host features. Finally, integrating microbial and host features revealed host-microbe interactions that are specific to psoriasis or particular psoriasis subgroups.
Conclusion

To our knowledge, this is the first study that provides a comprehensive view of gut microbial function and corresponding host response in psoriasis patients. Our findings provide insight into factors that may affect the development of comorbidities in psoriasis patients and may hold diagnostic potential for early identification of psoriasis patients at risk for these comorbidities.
Understanding and reconciling different approaches for quantifying nitrogen use efficiency in cropping systems
Authors: Quan Zhi , Zhang Xin , Fang Yunting , Davidson Eric 
Published: August 2020

Abstract
Nitrogen use efficiency (NUE) has been widely used in cropping systems to study nitrogen (N) cycles and inform N management on various spatial scales, from a single plant to the globe. Although the number of NUE studies is growing, interpretation of results is unfortunately hindered by widely differing definitions and quantification methods among studies, suggesting a pressing need for harmonization of approaches. Here, we proposed a conceptual framework to understanding the differences and connections among three major approaches for determining NUE, namely, the difference approach, 15N tracer approach, and N balance approach. Using the Chinese cereal cropping system as an example, we demonstrated that the results of those NUE assessments could be very different even for the same cropping system (0.32, 0.24, and 0.52, respectively). Such a difference is attributable largely to the soil legacy effect and could be reduced by extending the observations for a longer term. This study provides the necessary understanding to reconcile NUE values from different approaches and consequently to better inform N management in cropping systems.