bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating elicited judgments of turtle captures for data‐limited fisheries management
Authors: Arlidge William N. S. , Alfaro‐Shigueto Joanna , Ibanez‐Erquiaga Bruno , Mangel Jeffrey C. , Squires Dale , Milner‐Gulland Eleanor J. 
Published: February 2020

AbstractWe compare judgments of green turtle (Chelonia mydas) captures elicited from local gillnet skippers and not‐for‐profit conservation organization employees operating in a small‐scale fishery in Peru, to capture rates calculated from a voluntary at‐sea observer program operating out of the same fishery. To reduce cognitive biases and more accurately quantify uncertainty in our experts’ judgments, we followed the IDEA (“Investigate,” “Discuss,” “Estimate,” and “Aggregate”) structured elicitation protocol. The elicited mean monthly estimates of green turtle gillnet captures within summer and winter fishing seasons were higher than the equivalent green turtle capture rates calculated from the fisheries observer data; however, no statistically significant differences were identified when comparing the means of the datasets using bootstrap hypothesis tests (winter observed difference‐in‐means: 83.15, adj mean ± SD = 42.39 ± 32.59; summer observed difference‐in‐means: 68.58, adj mean ± SD = 54.06 ± 41.22). We investigated respondent performance in relation to the observer data capture rates. The not‐for‐profit employees scored high on accuracy and calibration performance metrics. The gillnet skippers’ judgments ranked higher on informativeness yet lower on accuracy and calibration, potentially reflective of overconfident judgments. This research presents a new context for using the IDEA protocol, which may prove helpful for rapid, exploratory evaluations of capture and bycatch impact in data‐limited small‐scale fishery management scenarios.
S1 guidelines: Tinea capitis
Authors: Mayser Peter , Nenoff Pietro , Reinel Dieter , Abeck Dietrich , Brasch Jochen , Daeschlein Georg , Effendy Isaak , Ginter‐Hanselmayer Gabriele , Gräser Yvonne , Hipler Uta‐Christina , Höger Peter , Kolb‐Mäurer Annette , Ott Hagen , Schaller Martin , Zidane Miriam 
Published: February 2020

SummaryTinea capitis describes a dermatophyte infection of scalp and hair that predominately occurs in children. The diagnostic workup includes microscopic examination, culture and/or molecular tests. Treatment is guided by the specific organism involved and should consist of systemic agents as well as adjuvant topical treatment. The aim of the present update of the interdisciplinary German S1 guidelines is to provide dermatologists, pediatricians and general practitioners with a decision tool for selecting and implementing appropriate diagnostic and therapeutic measures in patients with tinea capitis. The guidelines were developed based on current international guidelines, in particular the 2010 European Society for Pediatric Dermatology guidelines and the 2014 British Association of Dermatologists guidelines, as well as on a review of the literature conducted by the guideline committee. This multidisciplinary committee consists of representatives from the German Society of Dermatology (DDG), the German‐Speaking Mycological Society (DMykG), the German Society for Hygiene and Microbiology (DGHM), the German Society of Pediatric and Adolescent Medicine (DGKJ) and the German Society for Pediatric Infectious Diseases (DGPI). The Division of Evidence‐based Medicine (dEBM) provided methodological assistance. The guidelines were approved by the participating medical societies following a comprehensive internal and external review.
miRNA dysregulation in ischaemic stroke: Focus on diagnosis, prognosis, therapeutic and protective biomarkers
Authors: Vasudeva Kanika , Munshi Anjana 
Published: February 2020

AbstractStroke is one of the leading causes of death and disability in both developing and developed countries. Biomarkers for stroke and its outcome can greatly facilitate early detection and management of the disease. miRNAs have been explored for their potential as biomarkers for diagnosis, prognosis and brain injury in ischaemic stroke. A substantial body of evidence suggests that miRNAs play key roles in numerous cellular changes following ischaemic stroke including mitochondrial dysfunction, energy failure, cytokine‐mediated cytotoxicity, oxidative stress, activation of glial cells, increased intracellular calcium levels inflammatory responses and disruption of the blood–brain barrier (BBB). In addition, targeting specific miRNAs, therapeutic modulation of brain injury and apoptosis can also be achieved. Therefore, the current review has been compiled within an aim to give an overview of the developments exploiting miRNAs at different stages of stroke as prognostic, diagnostic, protective and therapeutic biomarkers.
Changing estuaries and impacts on juvenile salmon: A systematic review
Authors: Hodgson Emma E. , Wilson Samantha M. , Moore Jonathan W. 
Published: February 2020

AbstractEstuaries are productive ecosystems providing important habitat for a diversity of species, yet they also experience intense levels of anthropogenic development. To inform decision‐making, it is essential to understand the pathways of impacts of particular human activities, especially those that affect species such as salmon, which have high ecological, social‐cultural and economic values. Salmon systems provide an opportunity to build from the substantial body of research on responses to estuary developments and take stock of what is known. We conducted a systematic English‐language literature review on the responses of juvenile salmon to anthropogenic activities in estuaries and nearshore areas asking: what has been studied, where are the major knowledge gaps and how do stressors affect salmon? We found a substantial body of research (n = 167 studies; 1,369 comparative tests) to help understand responses of juvenile salmon to 24 activities and their 14 stressors. Across studies, 82% of the research was conducted in the eastern Pacific (Oregon and Washington, USA and British Columbia, Canada) showing a limited geographical scope. Using a semiquantitative approach to summarize the literature, including a weight‐of‐evidence metric, we found a range of results from low to moderate–high confidence in the consequences of the stressors. For example, we found moderate–high confidence in the negative impacts of pollutants and sea lice and moderate confidence in negative impacts from connectivity loss and changes in flow. Our results suggest that overall, multiple anthropogenic activities cause negative impacts across ecological scales. However, our results also reveal knowledge gaps resulting from minimal research on particular species (e.g. sockeye salmon), regions (e.g. Atlantic) or stressors (e.g. entrainment) that would be expedient areas for future research. With estuaries acting as a nexus of biological and societal importance and hotspots of ongoing development, the insights gained here can contribute to informed decision‐making.
Individual agency and socio‐spatial change in regional development: Conceptualizing governance entrepreneurship
Authors: Döringer Stefanie 
Published: February 2020

AbstractAlthough scholars and practitioners increasingly highlight the role of individuals in initiating socio‐spatial change processes in regional development, there is still little conceptual and empirical knowledge concerning this phenomenon. Therefore, the aim of this paper is to gain a deeper theoretical understanding of entrepreneurial individuals in local and regional governance and to provide a more comprehensive framework for investigating individual agency and socio‐spatial change. In concepts of local and regional governance, the role of individuals has been overshadowed by the focus on institutional and organizational structures. Policy and institutional entrepreneurship literature stresses the importance of individual capabilities for identifying windows of opportunity and promoting policy and institutional change. However, it reveals some shortcomings concerning the influence of entrepreneurial individuals in governance itself. By combining both strands of literature, the concept of governance entrepreneurship is introduced here. It accentuates the role of entrepreneurial individuals in initiating change in local and regional governance by establishing or transforming actor constellations, interaction modes, or decision‐making territories. Finally, the interrelatedness of the concepts of institutional, policy, and governance entrepreneurship is discussed in order to gain a deeper understanding of these different types of transformative agency.
Academic and teacher expatriates: Mobilities, positionalities, and subjectivities
Authors: Koh Sin Yee , Sin I Lin 
Published: February 2020

AbstractForeign academics and international school teachers have received little attention in migration studies and human geography despite their rapidly growing numbers and diversity in the global education landscape. This paper explores the inconsistent terms and categorical definitions attached to them and puts forth the value of approaching them as migrants under the term “expatriate.” It critically reviews an emerging body of work, led by human resource management and education literature, which uncovers the complexities and unique specificities of their mobilities. Our review reveals the diverse and uneven mobility structures, practices, and outcomes of academic and teacher expatriation that are stratified by gender, age, class, race, ethnicity, and nationality. Using the concept of translocational positionality, we argue that these intersectional positions must be situated within geographical contexts of power and differentiation to make visible the multiple, contingent, and contradictory realities of such expatriation. Doing so opens avenues for more nuanced and balanced insights into the privileges and vulnerabilities that confront these expatriates and which make them distinct and worthy of study.
The effect of mindfulness training on burnout syndrome in nursing: A systematic review and meta‐analysis
Authors: Suleiman‐Martos Nora , Gomez‐Urquiza Jose L. , Aguayo‐Estremera Raimundo , Cañadas‐De La Fuente Guillermo A. , De La Fuente‐Solana Emilia I. , Albendín‐García Luis 
Published: February 2020

AbstractAimTo analyse the effect of mindfulness training on levels of burnout among nurses.BackgroundBurnout syndrome is a common occupational hazard for nursing staff. Mindfulness training has been proposed as a valid intervention for burnout.DesignSystematic review and meta‐analysis.Data sourcesThe CINAHL, LILACS, Medline, ProQuest, PsycINFO, Scielo and Scopus databases were consulted, using the search equation ‘Nurs * AND burnout AND mindfulness’. There was no restriction on the year of publication.Review methodsPapers were selected for analysis in accordance with the PRISMA guidelines. The meta‐analysis was carried out using Review Manager 5.3 software.ResultsThe sample was of 17 articles including 632 nurses. Mindfulness training reduces levels of burnout, producing lower scores for emotional exhaustion and depersonalization and higher for personal accomplishment. The differences in the means were 1.32 (95% CI: −9.41–6.78), 1.91 (95% CI: −4.50–0.68) and 2.12 (95% CI: −9.91–14.14), respectively, between the intervention and control groups.ConclusionMindfulness training reduces the emotional burden and hence levels of burnout, among nurses. However, further randomized clinical trials are required.
A randomized controlled trial of the Effects of a telehealth educational intervention on medication adherence and disease activity in rheumatoid arthritis patients
Authors: Song Yuqing , Reifsnider Elizabeth , Zhao Shangping , Xie Xia , Chen Hong 
Published: February 2020

AbstractAimsTo examine the effects of a tailored telehealth educational intervention on medication adherence and disease activity in discharged patients with rheumatoid arthritis (RA).DesignAn un‐blinded randomized controlled trial.MethodsA total of 92 eligible patients were recruited from January 2015–December 2015. Participants were randomly assigned to either the intervention (N = 46) or control group (N = 46). The intervention group received four educational sessions delivered through a telephone across a 12‐week intervention. The content of the education mainly included: subject's knowledge about disease; treatment goals; the importance of taking medication correctly; side effect management; remembering to take medication. The control group received only standard care including discharge instructions. Outcome measures included medication adherence and disease activity.ResultsThe intervention group had significantly higher medication adherence compared with the control group at 12th and 24th week. There was no significant difference between two groups in disease activity at 12th and 24th week.ConclusionsThe telephone‐delivered tailored educational intervention effectively improved medication adherence among discharged patients with rheumatoid arthritis. However, no significant benefits of the intervention on disease activity were detected.ImpactGood medication adherence in rheumatoid arthritis patients contributes to controlling symptom and inflammation, preventing the progressive structural damage. This study demonstrated that the telehealth educational intervention could improve patients' medication adherence but did not have a direct impact on clinical condition in the short‐term. The intervention for discharged patients with rheumatoid arthritis can be integrated into the clinical setting by the nursing staff as follow‐up care.Trial registration number: ChiCTR‐IPR‐14005722.
Bibliometric analysis of qualitative research on patients’ experiences of intestinal stoma published between 2002 ‐ 2018
Authors: Capilla‐Díaz Concepción , Durán‐López Maria I. , Martínez‐Guerrero Juan M. , Reina‐Leal Liliana M. , Gómez‐Urquiza José L. , Gálvez‐González María , Hueso‐Montoro César 
Published: February 2020

AbstractAimsThe purpose of this paper was to perform a bibliometric analysis of the production of qualitative research in scientific journals through aggregation by levels and to identify factors of diversity, such as types of designs, in qualitative research on the experience of having an intestinal stoma between 2002 and 2018.DesignDescriptive bibliometric study focused on the production of qualitative research on the subject of study, on three levels: micro, meso and macro.MethodsDatabases such as PubMed, CINAHL, Web of Knowledge, Scopus, SciELO, CUIDEN, Lilacs and Google Scholar were used to collect the data, between August ‐ November 2018.ResultsNursing was the main area of knowledge. Brazil was the predominant country of origin. The most productive journal was the Journal of Wound, Ostomy & Continence Nursing. English and Portuguese were the main languages of scientific communication. The number of authors was typically between 2 and 6. Authors conducted descriptive and phenomenological studies.ConclusionThe present bibliometric study helps us to map the qualitative research on the experiences of individuals with an intestinal stoma and to understand patterns in the designs, methods, disciplines and journals involved in this area of research. This will allow nurses to have a leading contribution to stoma care at their disposal.
CircPRMT5 circular RNA promotes proliferation of colorectal cancer through sponging miR‐377 to induce E2F3 expression
Authors: Yang Bairen , Du Ke , Yang Chuanhua , Xiang Lili , Xu Ying , Cao Chen , Zhang Junhui , Liu Wenneng 
Published: February 2020

AbstractCircPRTM5 is associated with cell proliferation and migration in many kinds of malignancies. However, the functions and mechanisms of CircPRTM5 in CRC progression remain unclear. We explored the role and the mechanisms of CircPRTM5 in the development of CRC. Tissues of CRC patients and matched adjacent non‐tumour tissues were collected to evaluate the expression of CircPRTM5. The expression of CircPRTM5 in CRC tissues was significantly higher than that in adjacent tissues. The biological functions of CircPRTM5 in CRC were determined by overexpression and down‐regulation of CircPRTM5 in CRC cells in vitro and in vivo. The results indicate that knockdown of CircPRTM5 can significantly inhibit the proliferation of CRC cells. The potential mechanisms of CircPRTM5 in CRC development were identified by RT‐qPCR, Western blotting analysis and luciferase reporter assay. CircPRTM5 competitively regulates the expression of E2F3 by capillary adsorption of miR‐377. CircPRMT5 regulates CRC proliferation by regulating the expression of E2F3, which affects the expression of the cell cycle‐associated proteins cyclinD1 and CDK2. CircPRTM5 exerts critical regulatory role in CRC progression by sponging miR‐377 to induce E2F3 expression.
A multicomponent herbal feed additive improves somatic cell counts in dairy cows ‐ a two stage, multicentre, placebo‐controlled long‐term on‐farm trial
Authors: Walkenhorst Michael , Leiber Florian , Maeschli Ariane , Kapp Alexandra N. , Spengler‐Neff Anet , Faleschini Maria Teresa , Garo Eliane , Hamburger Matthias , Potterat Olivier , Mayer Philipp , Graf‐Schiller Sandra , Bieber Anna 
Published: February 2020

AbstractIn contrast to natural and historical diets of wild and domesticated ruminants, the diversity of plant species is limited in diets of modern dairy cows. Are “production diseases” linked to this? We conducted a trial to test the effects of a multicomponent herbal feed additive (HFA) on health, performance and fertility traits. A dose‐finding study (DF) with 62 cows on 11 commercial farms compared a low (50 g) and a high (100 g) dose of HFA (HFA‐50, HFA‐100) with a placebo (PL). In a subsequent field trial (FT) with 280 cows on 30 commercial farms, HFA‐100 was compared to PL. Cows were randomly assigned to HFA and PL groups and received HFA or PL individually daily from 14 days pre‐ to 300 days post‐calving. Data were analysed with mixed effects models. No differences between HFA and PL were found regarding performance, body condition score and overall culling rates. A tendency towards lower milk urea for HFA‐100 compared to PL (p = .06) was found in DF. HFA significantly reduced elevated milk acetone observations (≥10 mg/L) in the first 10 lactation weeks (HFA‐100: 4%; HFA‐50: 4%; PL: 12%) in DF. HFA‐50 significantly reduced lameness incidence (HFA‐100: 11%; HFA‐50: 2%; PL: 14%) in DF. Calving intervals were 15 days shorter in HFA compared to PL in both trials, which could be confirmed by tendency (p = .07) in FT. In both trials, the proportion of test days with elevated somatic cell score (≥3.0) was significantly lower in HFA compared to PL (DF: HFA‐100: 40%, HFA‐50: 45% and PL: 55%; FT: HFA‐100: 38% and PL: 55%) which is also reflected by tendency (p = .08) in lower culling rates due to udder diseases in FT. HFA showed no negative impact on any of the measured parameters. The effects of HFA indicate a potential of phytochemically rich and diverse feed additives for dairy cows' nutrition and physiology.
Effect of nephrology follow‐up on long‐term outcomes in patients with acute kidney injury: A systematic review and meta‐analysis
Authors: Ye Nan , Xu Ying , Bellomo Rinaldo , Gallagher Martin , Wang Amanda Y. 
Published: February 2020

AbstractAimAcute kidney injury (AKI) is associated with poor short‐term and long‐term clinical outcomes. The role of nephrology follow‐up in post‐AKI management remains uncertain.MethodsA systematic review and meta‐analysis were performed examining all randomized controlled trials and observational studies assessing the effect of nephrology follow‐up on patients' clinical outcomes. The primary outcome was all‐cause mortality. The secondary outcomes were renal outcomes, which were defined as a composite of requirement of permanent dialysis and recurrent AKI. Pooled analysis was performed using a random‐effect model.ResultsWe identified six studies (8972 patients, mean follow‐up of 49 months). Five were retrospective cohort studies and one was a prospective cohort study. Risk of bias was a concern with all studied. Only four studies reported primary and/or secondary outcomes and were included. Compared with patients without nephrology follow‐up, patients with nephrology follow‐up had significantly reduced mortality by 22% (three studies, 3240 patients, relative risk [RR] = 0.78, 95% confidence interval [CI] = 0.70‐0.88, I2 = 0.0%). Nephrology follow‐up did not improve composite renal outcomes with high heterogeneity due to significant differences in reported renal outcomes and follow‐up period (two studies, 2537 patients, RR = 1.72, 95% CI = 0.49‐6.05, I2 = 90.1%).ConclusionCurrent evidence from observational studies is biased. It suggests long‐term survival benefits with post‐discharge nephrology follow‐up in AKI patients. However, due to its low quality, such evidence is only hypothesis‐generating. Nonetheless, it provides a rationale for future randomized controlled trials of nephrology follow‐up in AKI patients.SUMMARY AT A GLANCEThe present meta‐analysis assessed the effect of nephrology follow‐up on patients' clinical outcomes, and suggested long‐term survival benefits in acute kidney injury (AKI) survivors. Although the study inherently comprises potential risks of bias due to paucity of available data, the results provide a rationale for future randomized controlled trials.
Evaluation of the minimal erythema dose for UVB and UVA in context of skin phototype and nature of photodermatosis
Authors: Welti Michèle , Ramelyte Egle , Dummer Reinhard , Imhof Laurence 
Published: February 2020

AbstractBackgroundPhototesting is part of the standard procedure for the evaluation of patients with photosensitivity disorders. The response of patients to targeted UVB or UVA radiation helps to find out more about the nature of photodermatosis. Nevertheless, there are no default values of the minimal erythema dose (MED).MethodsThis study evaluated data of 203 patients (131 female, 72 male, mean age 52 years) who were referred for phototesting to the University Hospital Zurich between 2012 and 2017. We retrospectively analyzed the demographic data, medical history, skin phototype, reaction to UVB and UVA radiation, and, if present, the diagnosis of photodermatosis. In patients who did not develop erythema at the highest tested UV doses, the next logical increment was taken for analysis. In case of UVA, the two periphery doses could not be evaluated due to technical issues, so the closest reliable UVA doses were used.ResultsThe MED‐UVB correlated with the skin type and increased with a higher phototype. No such correlation could be seen for MED‐UVA. However, the MED‐UVA was significantly reduced in patients with photodermatosis without significant differences between the subgroups of photodermatosis. More than half of the patients did not show a reduced MED despite a diagnosed photodermatosis.ConclusionWe showed, how different skin types with and without photodermatosis react to UV radiation. Based on the results, we suggested threshold doses that can be chosen for phototesting, presented which doses can be considered pathologic and showed the probability of a pathologic MED in correlation with a diagnosed photodermatosis.