bluuebunny/crossref_metadata_2025_split huggingface dataset:
PARENT-CHILD RELATIONSHIPS AND SLEEP QUALITY AMONG CHINESE AGING PARENTS
Authors: Wang Haowei , Kim Kyungmin , Burr Jeffrey , Wu Bei 
Published: December 2019

Abstract
Relationships with adult children play an important role in older adults’ well-being. However, little is known about the association between parent-child relations and aging parents’ sleep quality, which is an emerging health issue that is closely related to individuals’ physical and mental well-being in later life. With the largest aging population, China has experienced rapid changes of family structure and traditional norms regarding parent-child ties. This study focused on different dimensions of parent-child relationships (i.e., upward/downward financial and instrumental support, emotional closeness) in Chinese aging families. This study examined the association between parent-child relationships and older parents’ sleep quality, comparing one-child and multiple-children Chinese families. Utilizing the 2014 wave of the Chinese Longitudinal Aging and Social Survey, we analyze data from 8,450 respondents (aged 60+) who had at least one living child. Descriptive analysis showed that parents with multiple children engaged in more intense financial exchanges, less frequent instrumental support, and lower levels of emotional closeness with their adult children compared to their counterparts with only one child. Logistic regression models revealed that older parents who received more instrumental support were more likely to report sleep difficulty in both one-child and multiple-children families. For parents with multiple children, the overall level of financial transfers from children was negatively associated with having sleep difficulties, while the variability of financial transfers across multiple children was positively associated with having sleep difficulty. Findings highlight the importance of considering family dynamics in studying sleep quality among Chinese older adults.
THE APPLICATION OF MASS OBSERVATION DATA IN SOCIAL RESEARCH
Authors: Kingston Paul 
Published: December 2019

Abstract
Responding to the opportunities and challenges of an ageing world the University of Chester established the Centre for Ageing, Mental Health and Veterans’ Studies in 2013 to provide research, consultancy and education, with the aim of promoting innovation in health and social care services for older people. This symposium brings together researchers from a wide range of disciplines and career stages, to explore the utility of Mass observation data in social research in the field of gerontology. The Mass Observation Project, established in 1937, documents the lives of ordinary people living in the UK, and explores a wide range of social issues. The symposium comprises four separate papers. The Methodological Relevance of Mass Observation Data: This preliminary overview will outline the mass observation archive, highlighting challenges and issues encountered utilising the data produced in social research. Personal Narratives of Ageing: This paper presents personal narratives reflecting on the ageing process, and growing older in the UK. The Health Impact of Scams: This presentation will offer new and alternate insights into ‘scams’ and the health effects of fraud on older people, using data from the mass observation directive commissioned by the centre. Perceptions of Dementia: This paper presents a perspective on the public knowledge and understanding about dementia not previously considered, where respondents have written openly about their own experiences, and reflected on their perception of the wider public’s knowledge and understanding about dementia.
ALTERATIONS IN TARGETED METABOLOMICS PRIOR TO UNINTENTIONAL WEIGHT LOSS IN OLDER ADULTS
Authors: Baugh Mary Elizabeth , Ilkayeva Olga R , Bain James R , Muehlbauer Michael J , Marron Megan M , Newman Anne B , Farsijani Samaneh , Kritchevsky Stephen 
Published: December 2019

Abstract
In older adults, unintentional weight loss (UWL) is associated with poor outcomes, but its pathophysiology remains poorly understood. We sought to identify potential biomarkers of UWL using targeted metabolomics, including 8 conventional metabolites, 45 acylcarnitines, and 15 amino acids. We identified individuals from the Cardiovascular Health Study All Stars with UWL (n=40) or weight stability (WS; n=40) from Years 9 to 11. Participants had WS through Year 8. UWL was defined as experiencing &gt;6% weight loss from Years 9 to 11 and self-reporting that loss as unintentional. Mean plasma metabolite concentrations measured in Year 9 were compared between individuals with UWL or WS between Years 9 and 11. The strongest signals in metabolomic differences between individuals going on to experience UWL versus WS were observed among the branched-chain amino acids, valine (236.54 ± 54.43 vs. 215.79 ± 32.69 μM, 95%CI: -40.81, -0.70) and isoleucine/leucine (159.09 ± 36.53 vs. 142.75 ± 23.78 μM, 95%CI:-30.10, -2.59); lactate (1.23 ± 0.44 vs. 1.00 ± 0.57 μM, 95%CI: -0.45, -0.001); histidine (35.69 ± 5.33 vs. 38.62 ± 4.86 μM, 95%CI: 0.65, 5.20); the medium-chain acylcarnitine octenoyl carnitine (C8:1) (0.23 ± 0.10 vs. 0.29 ± 0.14 μM, 95%CI: 0.01, 0.12); and long-chain acylcarnitine myristoyl carnitine (C14) (0.04 ± 0.01 vs. 0.03 ± 0.01 μM, 95%CI: -0.01, -0.002). These findings suggest altered branched-chain amino acid and fatty acid metabolism and increased oxidative stress and inflammation may be evident before individuals undergo UWL. Further investigation of these pathways may reveal novel preventive or treatment strategies for UWL.
EVALUATING GERIATRIC WORKFORCE DEVELOPMENT NEEDS AMONG HOSPITALS USING NICHE BENCHMARKING DATA
Authors: Thompson Roy A , Matters Loretta , Corazzini Kirsten , McConnell Eleanor 
Published: December 2019

Abstract
The Nurses Improving Care for Health System Elders (NICHE) program aims to improve geriatric care competencies for improved care quality. A quantitative descriptive design utilizing secondary data analysis was done to evaluate geriatric workforce enhancement efforts in one acute healthcare system. Data were collected using the Geriatric Institutional Assessment Profile (GIAP) from 2008 and 2013. The GIAP measures perceived professional issues (disagreements among staff and families, limited access to geriatric services, vulnerability to legal action, intensity and burden of behavioral problems) on a Likert scale from best=0 to poor=10. Staff perception of the Geriatric Care Environment was scored by the GIAP as: age sensitive care delivery (0-40), institutional values (0-28), resource availability (0-32) and capacity for collaboration (0-12). Higher scores on the Geriatric Care Environment reflected improvements. Independent sample t-tests examined changes in baseline scores. Post-NICHE implementation, compared to peer hospitals by teaching status and bed size in 3 hospitals there were significantly (p&lt;0.05) improved scores for: access to geriatric services (2.79-3.21), burden of behavioral problems (2.40-3.15), aging sensitivity care delivery (26.05-29.53), institutional values (18.85-19.59) and resource availability (19.51-19.97). Peer hospitals had significantly (p&lt;0.05) better scores for: disagreements among staff about treatment of older adults (1.63-1.94) and capacity for collaboration (7.72-7.99). Findings indicate improvement in perceived professional issues and need for improvement in the geriatric care environment and care redesign to progress to becoming an Age-Friendly health system. This was an initial step in a health system to improve care quality through health workforce development.
THE LFDSS DETECTS HIGH-RISK FINANCIAL DECISION-MAKING IN COGNITIVELY VULNERABLE OLDER ADULTS
Authors: Campbell Rebecca J , Lichtenberg Peter 
Published: December 2019

Abstract
The Lichtenberg Financial Decision-Making Screening Scale (LFDSS) is a brief screening tool that quantifies an individual’s informed decision making and risk for exploitation in a real-world financial transaction. Previous literature found that the ideal cut-off score for those at higher risk of financial exploitation was five and above. The purpose of the present study was to examine the utility of the LFDSS as a screening tool for financial decision-making ability in a high-risk sample of people with cognitive impairment. The sample was obtained from the Michigan Alzheimer’s Disease Center and was comprised of both cognitively healthy individuals (n=73) and those with cognitive impairment (n=45). All participants completed the LFDSS as part of a larger test battery. A Pearson chi-square analysis was used to examine group differences in financial decision-making risk between cognitively healthy individuals and those with cognitive impairment. A Pearson chi-square analysis found that those who had cognitive impairment were significantly more likely to score above the cut-off for high-risk financial decision-making compared to those who were cognitively healthy (χ2(1)=4.61, p=.032). The base rate of high-risk financial decision-making was 3.2x greater for those with cognitive impairment compared (17.7%) to those who were cognitively healthy (5.5%). These results demonstrate the utility of the LFDSS to detect high-risk decision-making in individuals with cognitive impairment. This tool serves a need in many professional settings (e.g. doctor’s offices and Adult Protective Services) for a brief, standardized assessment measure of financial decision-making and exploitation risk for a real-world, significant financial transaction.
PERSISTENT THEMES IN WHERE WE LIVE AS WE ARE LIVING OUR VERY OLD LIVES
Authors: Moss Miriam S , Moss Sidney Z 
Published: December 2019

Abstract
After living in our suburban house in Pennsylvania for over five decades, as long term gerontologists we moved to Massachusetts. First, we rented a house for three years; then the homeowner decided to sell and we declined to buy. Now in our 90’s, we have been residents for four years of a town house in a retirement community in Massachusetts that emphasizes independence over dependency; it provides no meals or direct health care services. It is now our home and we have found that several themes persevere: (1) We adapt to the increasing presence of vulnerability in ourselves and in other older persons. (2) We try to maximize our sense of residential comfort and mastery (Golant, 2015) by asserting environmental proactivity ( Lawton , 1987). This reflects the continuity (Atchley, 1989) of our lives. (3) We recognize the ever-present complexities in our responses to personal and societal themes of ageism.
Video-assisted thoracoscopic thymectomy is feasible for large thymomas: a propensity-matched comparison
Authors: Weng Wenhan , Li Xiao , Meng Shushi , Liu Xianping , Peng Peng , Wang Zhenfan , Li Jianfeng , Wang Jun 
Published: December 2019

AbstractOBJECTIVESVideo-assisted thoracoscopic thymectomy is becoming the preferable approach for early-stage thymoma. However, large thymomas are still recognized as a relative contraindication due to the possible risk of incomplete resection or capsular disruption. Thus, the aim of this study is to evaluate the feasibility of video-assisted thoracoscopic thymectomy for large thymomas.METHODSPatients diagnosed with Masaoka stage I–IV thymoma between April 2001 and December 2018 were retrospectively reviewed. All patients were divided into 2 groups: thymoma &lt;5.0 cm (group A) and thymoma ≥5.0 cm (group B). Propensity score matching analysis was performed to compare postoperative results. Recurrence-free survival and overall survival were compared for oncological evaluation.RESULTSA total of 346 patients were included in this study. In the propensity score matching analysis, 126 patients were included both in group A and group B. There was no significant difference between these 2 groups in terms of the R0 resection rate (95.2% vs 94.4%, P = 1.000), conversion rate (1.6% vs 3.2%, P = 0.684), operation time (119.4 ± 48.4 vs 139.1 ± 46.6 min, P = 0.955), blood loss (93.2 ± 231.7 vs 100.5 ± 149.3 ml, P = 0.649), duration of chest drainage (2.7 ± 1.6 vs 2.8 ± 2.0 days, P = 0.184), length of hospitalization (5.0 ± 3.9 vs 5.2 ± 2.9 days, P = 0.628) or postoperative complications (5.9% vs 8.5%, P = 0.068). There was no significant difference between these 2 groups in terms of the overall survival (P = 0.271) and recurrence-free survival (P = 0.288).CONCLUSIONSVideo-assisted thoracoscopic thymectomy is a safe and effective approach for large thymomas (≥5 cm) with comparable surgical and oncological results.
Opossum Mammary Maturation as It Relates to Immune Cell Infiltration and Nutritional Gene Transcription
Authors: Fehrenkamp B D , Miller R D 
Published: December 2019

Synopsis
The mammary gland has evolved to accommodate the developmental needs of offspring in species-specific ways. This is particularly true for marsupials. Marsupial milk content changes dramatically throughout lactation in ways appearing timed with neonatal ontogeny and behavior. Here we investigate morphological restructuring within the mammaries throughout lactation in the gray short-tailed opossum, Monodelphis domestica. Substantial remodeling of the mammaries occurs throughout the first half of active lactation. It is not until the latter half of lactation that opossum mammaries appear histologically similar to active eutherian mammaries. Noteworthy was the presence of eosinophils in early developing mammary tissue, which correlated with elevated abundance of transcripts encoding the chemokine IL-16. The presence and abundance of whey protein transcripts within the opossum mammaries were also quantified. Whey acidic protein (WAP) transcript abundance peaked in the latter half of lactation and remained elevated through weaning. Minimal transcripts for the marsupial-specific Early and Late Lactation Proteins (ELP/LLP) were detected during active lactation. Elevated abundance of LLP transcripts was only detected prior to parturition. Overall, the results support the role of eosinophils in mammary restructuring appearing early in mammalian evolution, and describe key similarities and differences in nutritional protein transcript abundance among marsupial species.
Phylogeny of the Hawkmoth Tribe Ambulycini (Lepidoptera: Sphingidae): Mitogenomes from Museum Specimens Resolve Major Relationships
Authors: Timmermans Martijn J T N , Daghmoumi Sainab M , Glass Deborah , Hamilton Chris A , Kawahara Akito Y , Kitching Ian J 
Published: December 2019

Abstract
Ambulycini are a cosmopolitan tribe of the moth family Sphingidae, comprised of 10 genera, 3 of which are found in tropical Asia, 4 in the Neotropics, 1 in Africa, 1 in the Middle East, and 1 restricted to the islands of New Caledonia. Recent phylogenetic analyses of the tribe have yielded conflicting results, and some have suggested a close relationship of the monobasic New Caledonian genus CompsulyxHolloway, 1979 to the Neotropical ones, despite being found on opposite sides of the Pacific Ocean. Here, we investigate relationships within the tribe using full mitochondrial genomes, mainly derived from dry-pinned museum collections material. Mitogenomic data were obtained for 19 species representing nine of the 10 Ambulycini genera. Phylogenetic trees are in agreement with a tropical Asian origin for the tribe. Furthermore, results indicate that the Neotropical genus Adhemarius Oiticica Filho, 1939 is paraphyletic and support the notion that OrectaRothschild & Jordan 1903 and TrogolegnumRothschild & Jordan, 1903 may need to be synonymized. Finally, in our analysis the Neotropical genera do not collectively form a monophyletic group, due to a clade comprising the New Caledonian genus Compsulyx and the African genus BatocnemaRothschild & Jordan, 1903 being placed as sister to the Neotropical genus ProtambulyxRothschild & Jordan, 1903. This finding implies a complex biogeographic history and suggests the evolution of the tribe involved at least two long-distance dispersal events.
MIC distributions for amphotericin B, fluconazole, itraconazole, voriconazole, flucytosine and anidulafungin and 35 uncommon pathogenic yeast species from the UK determined using the CLSI broth microdilution method
Authors: Borman Andrew M , Muller Julian , Walsh-Quantick Jo , Szekely Adrien , Patterson Zoe , Palmer Michael D , Fraser Mark , Johnson Elizabeth M 
Published: December 2019

AbstractBackgroundEpidemiological cut-off values and clinical interpretive breakpoints have been developed for a number of antifungal agents with the most common Candida species that account for the majority of infections due to pathogenic yeasts species. However, less-common species, for which susceptibility data are limited, are increasingly reported in high-risk patients and breakthrough infections.MethodsThe UK National Mycology Reference Laboratory performs routine antifungal susceptibility testing of clinical yeast isolates submitted from across the UK. Between 2002 and 2016, &gt;32 000 isolates representing 94 different yeast species were referred to the laboratory. Here we present antifungal susceptibility profiles generated over this period for amphotericin B, fluconazole, voriconazole, itraconazole, anidulafungin and flucytosine against 35 species of uncommon yeast using CLSI methodologies. MIC data were interpreted against epidemiological cut-off values and clinical breakpoints developed with Candida albicans, in order to identify species with unusually skewed MIC distributions that potentially indicate resistance.ResultsPotential resistance to at least one antifungal agent (&gt;10% of isolates with MICs greater than the epidemiological cut-off or clinical breakpoint) was evidenced for 29/35 species examined here. Four species exhibited elevated MICs with all of the triazole antifungal drugs against which they were tested, and 21 species exhibited antifungal resistance to agents from at least two different classes of antifungal agent.ConclusionsThis study highlights a number of yeast species with unusual MIC distributions and provides data to aid clinicians in deciding which antifungal regimens may be appropriate when confronted with infections with rarer yeasts.
5 Precision animal welfare for pigs
Authors: Hulbert Lindsey E 
Published: December 2019

Abstract
Precision animal management (PAM), was a term created by engineers to describe technologies that improve the sustainability of intensive animal production systems. Focused efforts include improving product-efficiency and environmental impact (e.g. robotics in milk production). These PAM technologies have been incorporated in intensive swine production systems (e.g. feeding systems, waste-management). There is a perception that animal welfare efforts reduce efficiency, thus reducing sustainability. This perception is challenged with the development and application of precision animal welfare (PAW) technologies. Examples include: 1) a response system to stimulate sows to stand when they are crushing piglets (Swineguard, Swine Tech, Cedar Rapids, IA); 2) a visual-based automatic tracking system to detect sickness and agonistic interactions at an per-animal level (Schmidt et al., University of Nebraska at Lincoln, NE), and; 3) environmental enrichment (EE) that simultaneously provides mental-stimulation to pigs and automatically collects data (Hulbert et al., K-State, Manhattan, KS). The first two technologies may be applied for improved efficiency, which may not motivate animal caretakers to adopt new housing strategies. Restricted space-allowance limits behavior-expression, and consequently, limits the amount and type of data that can be gained from the technologies. Therefore, more work is needed to apply these technologies on pigs in alternative housing systems (e.g. pens instead of farrowing stalls). Animal welfare improves with EE, but pigs can extinguish EE-use (i.e. boredom) or destroy EE-devices. Non-destructible, stimulating EE were tested on mini-boars. The automated data served a behavioral-biomarker for detecting subclinical injury biomedical research projects. This EE can be scaled-up for commercial pigs and has great potential for improving welfare of pigs in intensive systems while simultaneous providing semi real-time information to animal caretakers at an per-animal level. For swine production, early-adopters and investors are needed to help animal welfare researchers and engineers to transform technologies from PAM into PAW.
194 Effects of maternal behavior at calving, parity and season on dam behavior during fenceline weaning
Authors: Rutherford William C , Parish Jane A , Montgomery Sarah M 
Published: December 2019

Abstract
The study objective was to assess the effect of maternal behavior at calving, parity and season on dam behavior during the first 24 h of fence-line weaning. Crossbred cattle (n = 58) were fitted with global positioning system collars on the day of weaning their calves and placed in a 10.1-ha pasture adjacent to their calves and separated by a common fence. Dam position was recorded at 5-minute intervals. Dam distance from the fence was analyzed using SAS PROC MIXED. Both maternal aggression score during calf handling within 24 h of calving (MA: 1 = flight response to 5 = fight response) and mothering aptitude score immediately following calf processing at calving (MOM: 1 = calf abandonment, 2 = cow retreats quickly with calf, 3 = cow flees chasing calf, 4 = cow walks away with calf, 5 = cow stays in immediate area with calf) affected mean daily distance to the fence (P &lt; 0.01). Dams assigned a MA of 5 maintained the greatest (P &lt; 0.01) mean daily distance from the fence (274.8 ± 1.0 m), whereas dams assigned a MA of 2 or 1 maintained the least (209.5 ± 0.8 m) (P &lt; 0.01) and second least (220.5 ± 0.8 m) (P &lt; 0.01) mean daily distance from the fence. Daily distance from the fence was in sequential order from greatest to least for dams with MOM scores of 3, 1, 5, 2, and 4 (P &lt; 0.01). Distance from the fence was greater (P &lt; 0.01) during fall than spring and greater (P &lt; 0.01) for multiparous than primiparous dams. This suggests that maternal behavior at calving is related to maternal behavior at weaning and that parity and season also influence weaning behavior of dams.