bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factores asociados con niveles adecuados de conocimientos sobre diabetes mellitus tipo 2 en pacientes de redes de servicios de salud en Bogotá D.C., Colombia
Authors: Vásquez Skarlet Marcell , Villar Juan Carlos , Torres-López Luz Ángela , Barrera Edgar Camilo , Balcázar-Muñoz Angela Manuela 
Published: December 2024

Introducción. Uno de los factores que influyen en la evolución clínica de los pacientes con diabetes mellitus tipo 2 (DMT2) es su nivel de conocimientos sobre su condición. Se conoce poco sobre el nivel de conocimientos sobre DMT2 en pacientes colombianos y sobre los factores asociados a dicho nivel.
Objetivo. Identificar los factores asociados con tener un nivel adecuado de conocimientos sobre DMT2 en pacientes con este diagnóstico atendidos en servicios ambulatorios de salud de Bogotá, D.C., Colombia.
Materiales y métodos. Estudio transversal realizado en 1068 adultos con DMT2 atendidos en 2021 en los servicios ambulatorios de 53 instituciones de salud pertenecientes a cuatro redes de salud de Bogotá, D.C. A partir de un caso seleccionado aleatoriamente en cada institución, se eligieron pacientes consecutivos para realizar una encuesta telefónica. A los participantes se les aplicó un cuestionario con 9 preguntas sobre DMT2 (6 preguntas fueron validadas debido a su relación con la antigüedad del diagnóstico (en años) o los niveles de HbA1c). Se definió como nivel adecuado de conocimientos responder correctamente 4 de las 6 preguntas validadas. Se realizó un análisis de regresión logística múltiple para identificar los factores asociados con tener un nivel adecuado de conocimientos.
Resultados. La mediana de edad de los participantes fue 63.97 años, 64.98% eran mujeres y en 26.68% el tiempo desde el diagnóstico era >10 años; además, 24.72% (IC95%: 22.23-27.39) mostraron un nivel adecuado de conocimientos. Ser mujer (OR=1.63), tener un nivel de escolaridad mayor a educación primaria (OR=1.82), tener una ocupación (OR=1.70), tener un diagnóstico de DMT2 >5 años (OR=1.49) y tener ≥1 comorbilidad/antecedente de condición de salud importante (OR=1.48) se asociaron con tener un nivel adecuado de conocimientos sobre DMT2.
Conclusiones. Uno de cada 4 pacientes con DMT2 en Bogotá muestra un nivel adecuado de conocimientos sobre su condición. Dada la cantidad y diversidad de pacientes con conocimientos inadecuados, es urgente implementar programas de educación, especialmente en hombres de bajo nivel educativo con diagnóstico reciente.
Characterization of a carbapenemase-producing Klebsiella pneumoniae isolate of a patient in an intensive care unit in Greece: A study of resistome, virulome, and mobilome
Authors: Tsolakidou Pandora , Papadimitriou Aikaterini , Kyriazidis Kyriazis Athanasios , Ilias Pessach , Mitka Stella , Chatzidimitriou Maria 
Published: December 2024

AbstractKlebsiella pneumoniae is a major pathogen associated with hospital-acquired infections, particularly those involving multidrug-resistant strains. Carbapenem resistance, often driven by carbapenemases such as KPC, VIM, OXA-48, and NDM, poses a significant challenge in clinical settings. This study reports on K. pneumoniae strain A165, isolated from a blood culture of a 51-year-old female patient hospitalized for respiratory distress post-SARS-CoV-2 infection. This K. pneumoniae strain exhibited resistance to several antibiotics, including carbapenems, cephalosporins, aminoglycosides, and fluoroquinolones, but remained susceptible to gentamicin, colistin, and trimethoprim-sulfamethoxazole. Next-generation sequencing was performed on Ion torrent platform, that revealed a genome size of 5,676,404 bp, including a chromosome and six plasmids. The strain was classified as sequence type 11 (ST11), a high-risk lineage associated with carbapenem resistance. The resistome of A165 included multiple β-lactamase genes, such as blaNDM-1 and blaOXA-48, as well as genes conferring resistance to other antibiotic classes. The virulome analysis identified genes involved in iron acquisition (yersiniabactin operon genes: ybtE, ybtT, irp1, irp2; aerobactin receptor: iutA), adhesion (mrkA-J, fimA-K), capsule and biofilm formation (rcsA, rcsB, ompA) and resistance to complement (traT) contributing to its pathogenic potential. The mobilome analysis revealed nine insertion sequences, including ISKpn1, ISKpn18, ISKpn43, ISKpn28, ISKpn14, ISEcp1, and IS6100. The strain also harbored six replicons: Col440II, ColRNAI, IncFIA(HI1), IncFIB(K), IncFII(K), and IncR, which are associated with the horizontal transfer of resistance and virulence genes. Comparative analysis with global isolates demonstrated the widespread dissemination of carbapenemase-producing K. pneumoniae, with notable occurrences in Europe, Asia, and the Americas. This study highlights the growing concern of multidrug-resistant K. pneumoniae in hospital settings and emphasizes the need for robust surveillance and infection control measures.
The influence of combustion temperature on the phase and morphological compositions of Si3N4‒Yb2O3 composites obtained by the SHS method
Authors: Shibakov I. A. , Zakorzhevskii V. V. 
Published: December 2024

The effect of combustion temperature on the phase composition and morphology of particles of SHS composites of the composition Si3N4‒Yb2O3 was studied. The combustion temperature was controlled using the silicon content in the reaction mixture. It was found that with an increase in the synthesis temperature, the content of α-Si3N4 decreases. Silicon ytterbium oxynitride is formed as a secondary phase. The morphology of the particles of the composition changes with an increase in the combustion temperature from the equiaxed form of α-Si3N4 to columnar crystals of β-Si3N4. Ill. 3. Ref. 7.
Noise Analysis of Distributed Acoustic Sensing (DAS) Data in Borehole Installations
Authors: Pecci Davide , Cesca Simone , Niemz Peter , Pankow Kristine , Carelli Giorgio , Grigoli Francesco 
Published: December 2024

Abstract
Distributed acoustic sensing (DAS) is a technology that is revolutionizing seismic data acquisition, particularly in borehole installations. Acting as a dense array of receivers, DAS provides high coverage, revealing time-depth patterns that are often hidden in data acquired with traditional seismometers. Its resilience to extreme temperature and pressure conditions, in which standard instrumentation typically fails, makes DAS reliable for microseismic monitoring operations in deep boreholes in geothermal environments. However, DAS faces challenges such as a lower signal-to-noise ratio compared to conventional geophones. DAS requires advanced denoising workflows in environments with high background noise, for example, from anthropogenic activities. A broader understanding and characterization of the noise observed in optical fibers is thus necessary and is still lacking. In this work, we aim to address this gap by analyzing noise data acquired from a fiber-optic cable installed in a monitoring well at the Utah Frontier Observatory for Research in Geothermal Energy Enhanced Geothermal System pilot project site in southcentral Utah, United States. Our proposed workflow combines power spectral density and phase analysis to assess the modulation of noise over time and depth for different frequencies and consequently to differentiate noise originating by anthropogenic sources at the surface from those further away from the industrial site. In addition, our analysis highlights noise components that may be related to instrumental noise from the interrogator, contributing to future noise mitigation strategies. This is further demonstrated through a direct comparison with noise observed by geophones coupled with the optical fiber in the same monitoring well.
Dysmenorrhea and recent treatment options in adolescents and young adults
Authors: Innocent Rani Vanitha , Dash Biswajit , Nancy Lal Monica , P Muthu Prasanna , Bagchi Sovan , Aruna V. , Prabha K. Suria 
Published: December 2024

Dysmenorrhea, or primary dysmenorrhea (PD), marked by menstrual cramps in the lower abdomen, is a common but often overlooked condition affecting a considerable number of women. The impact of dysmenorrhea extends beyond physical pain, often causing considerable disruption to daily activities, work, and social interactions. It significantly affects the quality of life, often causing absenteeism from school or work. Increased intrauterine prostaglandin secretion is linked to pelvic pain in PD. Diagnosis relies mainly on clinical assessment, considering symptoms and physical examination, with treatment aimed to enhance the quality of life. These menstrual cramps are frequently accompanied by other symptoms, such as headaches and nausea, which are believed to be due to prostaglandins released as the endometrium breaks down. A literature search using the keywords dysmenorrhea, menstrual pain, and hormonal contraceptives was done using the following databases: Google Scholar, ProQuest, ScienceDirect, Web of Science, Pubmed, and Scopus for articles published from 2015 to 2024. The literature study was done to find the connection of dysmenorrhea and menstrual pain with hormonal contraceptives. Common treatments include nonsteroidal anti-inflammatory drugs, hormonal contraceptives, and non-pharmacological interventions. This review provides an in-depth analysis of recent treatment advancements for dysmenorrhea, focusing on its pathophysiology, clinical diagnosis, and impact on women's quality of life. It evaluates current and emerging treatments, including pharmacological interventions, non-pharmacological therapies, surgical approaches, hormonal treatments, and investigational drugs, aiming to identify improvements in efficacy and side effects.
Removing and Rehabilitating the Burangin: South Korean Newspapers' Vagrancy Discourse in Support of State Violence
Authors: Jung Eunyoung 
Published: December 2024

The South Korean government used the burangin [vagrants] label to justify their massive wave of forced institutionalizations in the 1980s that resulted in countless abuses and many hundreds of deaths. The survivors' legal battles continue as the state, while no longer arresting so-called "vagrants," has never rectified the crimes of that period. Universal deinstitutionalization remains a controversial proposition in South Korea as the public is generally unaware of fundamental problems inherent in the practice of institutionalization itself. This paper uses critical discourse analysis to examine the discourse of vagrants in South Korean newspapers in the 1980s. While police cracked down on alleged vagrancy, the news media constructed the vagrant as an unsightly object, a threatening figure, and a target for rehabilitation. This article also discusses oppressive power mechanisms around this discourse which connects to issues of ableism and disability.
Comparison of proliferative potential in variants of ossifying fibroma (OF) of craniofacial complex
Authors: Zanwar Poonam R , Humbe Jayanti G , A Nandkhedkar Vaishali , Kaushal Nidhi , Wagh Savita , Mandale Mandakini S 
Published: December 2024

Comparison of proliferative potential in JTrOF , PsOF and OF of craniofacial complex using CDK4 and pHH3. Fibro-osseous lesions (FOL) refers to a poorly defined diverse group of lesions affecting the jaws and craniofacial complex. This spectrum of lesions includes fibrous dysplasia, cement-osseous dysplasia and two histological variants of ossifying fibroma - Despite benign neoplasms, both the variants of ossifying fibroma are characterized by rapid growth, potential for local invasiveness and a tendency to recur. According to the literature, the recurrence rate of JTrOF is about 20% where as PsOF is from 30-56%. Diagnosis is based on histopathology and imaging of the lesion. Early diagnosis allows for the resection of a smaller lesion , reducing the chance of damage to nearby structures. Various biomarkers such as oncogenes CDK4, MDM2, p53 and α-SMA have been investigated in bone pathology to predict biological behaviour of these lesions for precise treatment planning. Immunohistochemical expression of CDK4 and pHH3 will be assessed in histopathological diagnosed cases of juvenile trabecular ossifying fibroma, psammamatoid ossifying fibroma and conventional ossifying fibroma. The immunohistochemical expression of CDK4 was 100% in JTrOF and PsOF and 60% in OF. The expression of pHH3 was weak and focal in JTrOF and PsOF and also weak in OF. This study reveals the genetic mechanism involved in pathogenesis of aggressive variant of OF. Pre-treatment biopsy and CT scan are necessary for proper diagnosis and treatment planning of the lesion.
Choriocarcinoma induced thyrotoxicosis
Authors: Munshi Chaitanya , Bohra Murtaza , Mahindra Shraddha , Deshpande Kishor 
Published: December 2024

Paraneoplastic hyperthyroidism, although uncommon, is a known phenomenon in Germ cell tumors. Trophoblastic thyroidian hyperfunction is a complication of Choriocarcinoma.Choriocarcinoma is associated with high levels of Human Chorionic Gonadotropin (HCG). HCG is a glycoprotein produced by the placenta. It is structurally almost identical to Thyroid Stimulating Hormone (TSH). At high levels HCG can stimulate the TSH receptor causing Hyperthyroidism.This is a case of a 25 year old female diagnosed with metastatic Choriocarcinoma and concomitant Hyperthyroidism. After the first cycle of chemotherapy, the concentration of HCG decreased significantly. Simultaneously patient’s thyroid function test values normalized dramatically and the patient became euthyroid.The two known causative mechanisms are, enhanced thyrotropic activity by HCG and the molecular mimicry between HCG and TSH which causes release of Thyroxine from the thyroid gland.
Zamieszkując inne ciała – zwierzęce postaci i awatary
Authors: Mazur Emilia 
Published: December 2024

Poniższy artykuł dotyczy istotności perspektyw fenomenologicznych dla gier zwierzęcych, definiowanych w rozumieniu Gunnara Eggertsson’a, w których postać osoby grającej ma sygnalizować zwierzę. Przy użyciu przykładów gier takich jak Stray, Shelter 2 i Endling – Extinction is forever, traktujących zwierzęta jako pełnoprawnych protagonistów, wykazuję jak zwierzęce postaci i awatary oddziałują na doświadczenie grania, a także pozagrowe relacje ludzko-zwierzęce. Rozważania te mają na celu zrozumienie czy gry mogą zbliżać nas do lepszego rozumienia zwierzęcego Innego poprzez symulację jego doświadczeń i perspektyw. Niniejsze badanie wykorzystuje perspektywę krytycznych studiów nad zwierzętami i filozofii fenomenologicznej w celu głębszego opisu i zrozumienia interakcji ludzkich graczy ze zwierzęcymi postaciami. Podkreśla rolę ucieleśnienia w kształtowaniu transformatywnego doświadczenia rozgrywki.
Salud general, estilos y calidad de vida en atletas universitarios del noreste de México
Authors: Núñez-Rocha Georgina Mayela , Cano-Verdugo Guillermo , Hernández-Morales Jesús Antonio , Salinas-Martínez Ana María , Ávila-Ortíz María Natividad , Martínez-Hernández Rocío 
Published: December 2024

Objective: To examine the association between general health, lifestyles and quality of life according to sex and type of sport in high performance university athletes.
Materials and Methods: Cross-sectional study conducted in 512 high performance athletes. The sample consisted of all high-performance athletes from a public university. They were classified by type of sport according to M Bouet. The GHQ-12 instrument was applied to establish general health (GH), PEPS-I scale for lifestyles (LS) and SF-12 to establish quality of life (QOL). Student's t test and Chi2 were used, as well as Mann Whitney U test to establish differences by sex and Kruskal Wallis for comparisons by type of sport. The study was approved by the corresponding Ethics and Research Committee.
Results: The mean in GH was higher in women, and by type of sport no differences were observed (p>.05). As for LS, it was higher in men, and by type of sport, there was a difference in the nutrition dimension between the ball game group and the athletic group, and in self-refreshment between the chess and archery group and the ball game group (p=.0001). The average total QOL was higher in women. By type of sport, differences were observed in the physical function dimension between the combat and athletic groups, and in the general health dimension between the combat and ball game groups (p=.0001).
Conclusions: General health and quality of life were higher in women, while lifestyle was higher in men. Regarding the type of sport, general health did not show differences, but lifestyle and quality of life did.

Keywords: General health; Healthy lifestyle; Quality of life; College athletes.
Análise da mecânica respiratória de pacientes neurocríticos internados em uti geral ventilados nos modos prvc, pcv e vcv
Authors: Dos Santos Martins Gabriela , Nunes Stecker Daniéle , Martins de Fausto Daniela , Mattos de Castro Antonio Adolfo 
Published: December 2024

Objetivos: Comparar a mecânica ventilatória de pacientes neurocríticos em UTI, ventilados nos modos volume controlado (VCV), pressão controlada (PCV) e pressão regulada a volume controlado (PRVC).
Métodos: Foram recrutados 16 pacientes com media de idade de 56,1±19,7 que estiveram internados por 12,6±9,1 dias, sendo que 81,2% tiveram sobrevida. Estudo comparativo de três grupos que utilizaram modalidades ventilatórias: PRVC, PCV e VCV. Os pacientes foram ventilados com os parâmetros ajustados para gerar um volume corrente (VC) de 6 a 8 ml/Kg. Foram coletados: idade, gênero, diagnóstico, Glasgow, RASS, PAM, FC, f, FiO2, PEEP, pressão controlada, volume controlado ou pressão suporte, Ppico, Cd, Wr, P0.1, pH, PaCO2, PaO2, HCO3 e SaO2.
Resultados: Não encontramos diferenças entre os valores iniciais e finais e entre os grupos quanto à mecânica ventilatória dos 16 pacientes em ventilação mecânica internados em UTI. Encontramos correlação entre trabalho respiratório e pressão de pico (r = 0,87; p = 0,02), resistência expiratória e pressão de pico (r = 0,91; p = 0,01), complacência estática e elastância (r = -0,81; p = 0,04) e trabalho respiratório e resistência inspiratória (r = 1,0, p = 0,003), no modo PRVC; correlação entre pressão de pico e complacência dinâmica (r = -0,91, p = 0,03) e trabalho respiratório e elastância (r = -0,90, p = 0,03) no modo PCV; correlação entre elastância e complacência estática (r = -0,97, p = 0,004) e relação PaO2/FiO2 e trabalho respiratório (r = 0,99, p = 0,02) no modo VCV.
Conclusões: Não há diferença em parâmetros de mecânica ventilatória ao se ventilar mecanicamente pacientes neurocríticos em modos PRVC, PCV e VCV.
O coordenador pedagógico da SEDUC-SP como reformulador de política educacional
Authors: Miranda Nonato Assis de , Rosa Sanny Silva da , Jesus Filho Carlos Antonio Jovem de 
Published: December 2024

Este artigo apresenta os resultados parciais de uma pesquisa que analisou as repercussões do gerencialismo e da performatividade, materializadas no Método de Melhoria de Resultados (MMR) na perspectiva do coordenador pedagógico (CP) da rede estadual paulista (Seduc). As bases teóricas foram construídas a partir dos conceitos de performatividade, gerencialismo e de atuação de políticas (policy enactment) de Stephen Ball. A pesquisa foi orientada pelos fundamentos da abordagem qualitativa, com levantamento bibliográfico, análise documental e levantamento empírico. Os dados empíricos foram coletados em um Grupo de Discussão (GD), cujo propósito foi identificar as concepções dos CP sobre o MMR e seu papel como membro da gestão escolar. Além disso, buscou explorar as formas de atuação do coordenador pedagógico para colocar em prática o MMR. Para a realização da análise do material empírico coletado, optou-se pelo recurso metodológico da Análise de Prosa (AP). Os dados coletados evidenciaram que os CP da rede estadual paulista, ainda que sejam obrigados a atender a demandas por desempenho e cumprimento de metas, não atuam como mera caixa de ressonância da Seduc, mas adotam um discurso autoral e estratégias de ação que recontextualiza o MMR, adaptando-o à realidade e ao contexto escolar.
Blood-based sex-differential DNA methylation in Alzheimer’s disease
Authors: Yang Tianmi , Li Chunyu , Wei Qianqian , Cheng Yangfan , Xiao Yi , Shang Huifang 
Published: December 2024

Aim: We aim to explore the blood-based sex-differential DNA methylation profiles in patients with Alzheimer’s disease (AD).
Methods: The same analytical pipeline and meta-analysis procedure were applied to 254 patients with AD and 261 matched healthy controls (HC) from four blood-based datasets to identify sex-differentially methylated positions (sex-DMPs) and their biological functions. We further reviewed brain-based sex-DMPs previously reported in AD and intersected with blood-based sex-DMPs.
Results: We identified 134 sex-DMPs in AD, 88 were unique to AD, and 46 were shared with HC. Eleven novel sex-DMPs and 28 sex-DMPs consistent across blood and brain were recognized for the first time. Differentially methylated genes, such as COL25A1 , MSUT2 , ELAVL4 , SLC17A7 , EPHA4 , and PPP2CB , were closely related to the pathogenesis of AD. In addition, immune-related processes were enriched in the enrichment analysis.
Conclusion: Sex-differential DNA methylation in blood provides potential biomarkers for AD pathogenesis, and also points to potential drug targets for precision medicine.
Sikap dan Persepsi Pedagang Pengumpul Terhadap Keberadaan Sub Terminal Agribisnis Muara Taniran (Studi Kasus : Muara Taniran Kecamatan Angkinang, Kabupaten Hulu Sungai Selatan)
Authors: Yamani Muhammad Zaki , Hidayat Taufik , Anjardiani Luki 
Published: December 2024

Dampak keberadaan Subterminal Agribisnis di wilayah Kabupaten Hulu Sungai Selatan dengan menitik beratkan pada produksi komoditas yang dominan yaitu tanaman sayur-sayuran, dan STA sendiri menjadi salah satu fungsi infarastruktur sentral bagi petani dan pedagang bertemu dalam melaksanakan kegiatan pemasaran, Apakah dampak keberadaan Subterminal ini bisa menunjang dan menjadi salah satu kemudahan petani dalam memasarkan hasil pertaniannya, penelitian ini bertujuan untuk mengetahui sikap, persepsi dan harapan dari para pedagang dan pengumpul yang melakukan kegiatan di lingkungan Subterminal Agribisnis. Metode yang digunakn dalam penelitian ini adalah studi kasus. Hasil penelitian ini menunjukan bahwa sikap dari pedagang dan pengumpul adalah setuju dapat disimpulkan bahwa hasil dari perhitungan Thit tentang rentang skor individu responden mengasilkan nilai 17, dan melebihi dari skor rentang batasan antara positif dan negatif adalah 3, maka skor skala sikap dari responden menghasilkan skor sikap positif. Persepsi pedagang dan pengumpul menghasilkan hasil positif dan penilaian kebermanfaatannya dengan rata-rata rentang jawaban sangat setuju dan setuju dari 3 kategori pernyataan yaitu situasional, pengetahuan dan kepribadian. Harapan dari pedagang dan pengumpul yang berada dilingkungan Subterminal Agribisnis adalah mengharapkan instansi-instansi terkait agar mengambil peran masing-masing dalam pengembangan dan perbaikan SubTerminal Agrbisnis Muara Taniran.Kata kunci: subterminal agribisnis, sikap, persepsi