bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Complications and Comorbidities on the Intensive Care Length of Stay after Aneurysmal Subarachnoid Haemorrhage
Authors: Hammer Alexander , Ranaie Gholamreza , Erbguth Frank , Hohenhaus Matthias , Wenzl Martin , Killer-Oberpfalzer Monika , Steiner Hans-Herbert , Janssen Hendrik 
Published: April 2020

AbstractIn this observational study, we analysed a cohort of 164 subarachnoid haemorrhage survivors (until discharge from intensive care) with the aim to detect factors that influence the length of stay (LOS) in intensive care with multiple linear regression methods. Moreover, binary logistic regression methods were used to examine whether the time in intensive care is a predictor of outcome after 1 year. The clinical 1-year outcome was measured prospectively in a 12-month follow-up by telephone interview and categorised by the modified Rankin Scale (mRS). Patients who died during their stay in intensive care were excluded. Complications like pneumonia (β = 5.11; 95% CI = 1.75–8.46; p = 0.0031), sepsis (β = 9.54; 95% CI = 3.27–15.82; p = 0.0031), hydrocephalus (β = 4.63; 95% CI = 1.82–7.45; p = 0.0014), and delayed cerebral ischemia (DCI) (β = 3.38; 95% CI = 0.19–6.56; p = 0.038) were critical factors depending the LOS in intensive care as well as decompressive craniectomy (β = 5.02; 95% CI = 1.35–8.70; p = 0.0077). All analysed comorbidities such as hypertension, diabetes, hypothyroidism, cholesterinemia, and smoking history had no significant impact on the LOS in intensive care. LOS in intensive care (OR = 1.09; 95% CI = 1.03–1.15; p = 0.0023) as well as WFNS grade (OR = 3.72; 95% CI = 2.23–6.21; p < 0.0001) and age (OR = 1.06; 95% CI = 1.02–1.10; p = 0.0061) were significant factors that had an impact on the outcome after 1 year. Complications in intensive care but not comorbidities are associated with higher LOS in intensive care. LOS in intensive care is a modest but significant predictor of outcomes after subarachnoid haemorrhage.
Sciadonic acid derived from pine nuts as a food component to reduce plasma triglycerides by inhibiting the rat hepatic Δ9-desaturase
Authors: Pédrono Frédérique , Boulier-Monthéan Nathalie , Boissel Françoise , Ossemond Jordane , Viel Roselyne , Fautrel Alain , Marchix Justine , Dupont Didier 
Published: April 2020

AbstractSciadonic acid (Scia) is a Δ5-olefinic fatty acid that is particularly abundant in edible pine seeds and that exhibits an unusual polymethylene-interrupted structure. Earlier studies suggested that Scia inhibited the in vitro expression and activity of the Stearoyl-CoA Desaturase 1 (SCD1), the hepatic Δ9-desaturase involved in the formation of mono-unsaturated fatty acids. To confirm this hypothesis, rats were given 10% Scia in diets balanced out with n-6 and n-3 fatty acids. In those animals receiving the Scia supplement, monoene synthesis in the liver was reduced, which was partly attributed to the inhibition of SCD1 expression. As a consequence, the presence of Scia induced a 50% decrease in triglycerides in blood plasma due to a reduced level of VLDL-secreted triglycerides from the liver. In non-fasting conditions, results showed that Scia-induced inhibition of SCD1 led to a decrease in the proportions of 16:1n-7 and 18:1n-7 in the liver without impacting on the level of 18:1n-9, suggesting that only triglycerides with neosynthesized monoenes are marked out for release. In conclusion, this in vivo study confirms that Scia highly inhibits SCD1 expression and activity. The work was performed on normo-triglyceride rats over six weeks, suggesting promising effects on hyper-triglyceridemic models.
High functionality of DNA barcodes and revealed cases of cryptic diversity in Korean curved-horn moths (Lepidoptera: Gelechioidea)
Authors: Kim Sora , Lee Yerim , Mutanen Marko , Seung Jinbae , Lee Seunghwan 
Published: April 2020

AbstractCurved-horn moths or gelechioid moths (Lepidoptera: Gelechioidea) represent one of the most diverse lepidopteran groups. Due to the large number of species, generally small size of adults and subtle morphological differences, their confident identification requires tenacious and long-term dedication on their diversity. Over the past decade, DNA barcoding has repeatedly been used to elucidate boundaries of species in many large and difficult groups. Here, we conducted a test of DNA barcoding with the diverse fauna of Korean Gelechioidea with very little prior information of COI gene region from the area. Altogether 509 specimens representing 154 morphospecies were included in the study. The species assignments of all three tested species delimitation methods (ABGD, bPTP and PTP) were consistent with morphological identifications for 117 species (75.97%). A threshold of 2.5% genetic divergence was observed to differentiate the morphological species efficiently. Careful morphological examination of morphospecies exceeding 2.5% intraspecific variability prove cryptic diversity in three species (Neoblastobasis biceratala, Evippe albidoesella and Promalactis atriplagata). One morphospecies, Promalactis odaiensis, showed high intraspecific divergence while consisted of only a single MOTU. Overall, DNA barcoding was shown to provide a powerful tool to discriminate species of Korean Gelechioidea and reveal cases of cryptic diversity.
Prevalence and Risk Factors of Chronic Kidney Disease among Type 2 Diabetes Patients: A Cross-Sectional Study in Primary Care Practice
Authors: Jitraknatee Janjira , Ruengorn Chidchanok , Nochaiwong Surapon 
Published: April 2020

AbstractThis cross-sectional study aimed to investigate the prevalence and risk factors of chronic kidney disease (CKD) among 1,096 primary care type 2 diabetes (T2DM) patients in northern Thailand between October 2016 and September 2017. CKD was defined as estimated glomerular rate filtration values of <60 mL/min/1.73 m2. Prevalence with confidence intervals across CKD advanced stages 3–5 were estimated. Factors associated with CKD were evaluated by multivariate logistic regression. The overall prevalence of CKD was 24.4% (21.9–27.0), with severities of 11.4% (9.7–13.4), 6.8% (5.5–8.5), 4.6% (3.5–6.0), and 1.6% (1.0–2.5) for stages 3 A, 3B, 4, and 5, respectively. Regarding age and glycaemic control, individuals older than 75 years and those with a haemoglobin A1c ≥ 8% had the highest prevalence of 61.3% (51.7–70.1) and 38.6% (34.3–43.2), respectively. The multivariable logistic regression model explained 87.3% of the probability of CKD. The six independent significant risk factors of CKD were older age, retinopathy, albuminuria, haemoglobin A1c ≥ 7%, anaemia, and uric acid>7.5 mg/dL. A relatively high prevalence of CKD, especially in older patients and those with diabetic complications-related to poor glycaemic control, was encountered in this primary care practice. Early identification may help to target optimise care and prevention programs for CKD among T2DM patients.
Two‐way oxide rupture scheme for PUF implementation in low‐cost IoT systems
Authors: Lee C. , Lee J. , Lee Y. 
Published: April 2020

A two‐way oxide rupture scheme in a transistor is proposed for area‐efficient PUF implementation for low‐cost IoT systems. Compared to a conventional one‐way oxide rupture scheme, which requires a 4T unit cell structure, the proposed scheme allows a 2T unit cell structure, which enables up to 70% area reduction. A test chip is fabricated in 180 nm CMOS process to evaluate the effectiveness of the proposed scheme, confirming good randomness and uniqueness with small area overhead.
The EXOTIME project: signals in the O–C diagrams of the rapidly pulsating subdwarfs DW Lyn, V1636 Ori, QQ Vir, and V541 Hya
Authors: Mackebrandt F. , Schuh S. , Silvotti R. , Kim S.-L. , Kilkenny D. , Green E. M. , Lutz R. , Nagel T. , Provencal J. L. , Otani T. , Oswalt T. D. , Benatti S. , Lanteri L. , Bonanno A. , Frasca A. , Janulis R. , Paparó M. , Molnár L. , Claudi R. , Østensen R. H. 
Published: April 2020

Aims. We aim to investigate variations in the arrival time of coherent stellar pulsations due to the light-travel time effect to test for the presence of sub-stellar companions. Those companions are the key to one possible formation scenario of apparently single sub-dwarf B stars.
Methods. We made use of an extensive set of ground-based observations of the four large amplitude p-mode pulsators DW Lyn, V1636 Ori, QQ Vir, and V541 Hya. Observations of the TESS space telescope are available on two of the targets. The timing method compares the phase of sinusoidal fits to the full multi-epoch light curves with phases from the fit of a number of subsets of the original time series.
Results. Observations of the TESS mission do not sample the pulsations well enough to be useful due to the (currently) fixed two-minute cadence. From the ground-based observations, we infer evolutionary parameters from the arrival times. The residual signals show many statistically significant periodic signals, but no clear evidence for changes in arrival time induced by sub-stellar companions. The signals can be explained partly by mode beating effects. We derive upper limits on companion masses set by the observational campaign.
A flare in the optical spotted in the changing-look Seyfert NGC 3516
Authors: Ilić D. , Oknyansky V. , Popović L. Č. , Tsygankov S. S. , Belinski A. A. , Tatarnikov A. M. , Dodin A. V. , Shatsky N. I. , Ikonnikova N. P. , Rakić N. , Kovačević A. , Marčeta-Mandić S. , Burlak M. A. , Mishin E. O. , Metlova N. V. , Potanin S. A. , Zheltoukhov S. G. 
Published: April 2020

Context.We present observations from the short-term intensive optical campaign (from September 2019 to January 2020) of the changing-look Seyfert NGC 3516. This active galactic nucleus is known to have strong optical variability and has changed its type in the past. It has been in the low-activity state in the optical since 2013, with some rebrightening from the end of 2015 to the beginning of 2016, after which it remained dormant.Aims.We aim to study the photometric and spectral variability of NGC 3516 from the new observations inU- andB-bands and examine the profiles of the optical broad emission lines in order to demonstrate that this object may be entering a new state of activity.Methods.NGC 3516 has been monitored intensively for the past 4 months with an automated telescope inUandBfilters, enabling accurate photometry of 0.01 precision. Spectral observations were triggered when an increase in brightness was spotted. We support our analysis of past-episodes of violent variability with the UV and X-ray long-term light curves constructed from the archivalSwift/UVOT andSwift/XRT data.Results.An increase of the photometric magnitude is seen in bothUandBfilters to a maximum amplitude of 0.25 mag and 0.11 mag, respectively. During the flare, we observe stronger forbidden high-ionization iron lines ([Fe VII] and [Fe X]) than reported before, as well as the complex broad Hαand Hβlines. This is especially seen in Hα, which appears to be double-peaked. It seems that a very broad component of ∼10 000 km s−1in width in the Balmer lines is appearing. The trends in the optical, UV, and X-ray light curves are similar, with the amplitudes of variability being significantly larger in the case of UV and X-ray bands.Conclusions.The increase of the continuum emission, the variability of the coronal lines, and the very broad component in the Balmer lines may indicate that the AGN of NGC 3516 is finally leaving the low-activity state in which it has been for the last ∼3 years.
The role of Galactic H II regions in the formation of filaments
Authors: Zavagno A. , André Ph. , Schuller F. , Peretto N. , Shimajiri Y. , Arzoumanian D. , Csengeri T. , Figueira M. , Fuller G. A. , Könyves V. , Men’shchikov A. , Palmeirim P. , Roussel H. , Russeil D. , Schneider N. , Zhang S. 
Published: April 2020

Context. Massive stars and their associated ionized (H II) regions could play a key role in the formation and evolution of filaments that host star formation. However, the properties of filaments that interact with H II regions are still poorly known.
Aims. To investigate the impact of H II regions on the formation of filaments, we imaged the Galactic H II region RCW 120 and its surroundings where active star formation takes place and where the role of ionization feedback on the star formation process has already been studied.
Methods. We used the large-format bolometer camera ArTéMiS on the APEX telescope and combined the high-resolution ArTéMiS data at 350 and 450 μm with Herschel-SPIRE/HOBYS data at 350 and 500 μm to ensure good sensitivity to a broad range of spatial scales. This allowed us to study the dense gas distribution around RCW 120 with a resolution of 8′′ or 0.05 pc at a distance of 1.34 kpc.
Results. Our study allows us to trace the median radial intensity profile of the dense shell of RCW 120. This profile is asymmetric, indicating a clear compression from the H II region on the inner part of the shell. The profile is observed to be similarly asymmetric on both lateral sides of the shell, indicating a homogeneous compression over the surface. On the contrary, the profile analysis of a radial filament associated with the shell, but located outside of it, reveals a symmetric profile, suggesting that the compression from the ionized region is limited to the dense shell. The mean intensity profile of the internal part of the shell is well fitted by a Plummer-like profile with a deconvolved Gaussian full width at half maximum of 0.09 pc, as observed for filaments in low-mass star-forming regions.
Conclusions. Using ArTéMiS data combined with Herschel-SPIRE data, we found evidence for compression from the inner part of the RCW 120 ionized region on the surrounding dense shell. This compression is accompanied with a significant (factor 5) increase of the local column density. This study suggests that compression exerted by H II regions may play a key role in the formation of filaments and may further act on their hosted star formation. ArTéMiS data also suggest that RCW 120 might be a 3D ring, rather than a spherical structure.
Aktivitäten der Sektion Gewebetransplantation und Biotechnologie der Deutschen Ophthalmologischen Gesellschaft: Leistungsbericht 2018
Authors: Reinshagen Helga , Maier Philip Christian , Böhringer Daniel 
Published: April 2020

ZusammenfassungDie Sektion Gewebetransplantation und Biotechnologie legt ihren 9. Jahresbericht seit Bestehen vor. Zwar ist die Anzahl der eingeworbenen Hornhäute auf 10 840 angestiegen, von denen 7168 transplantiert wurden. Jedoch wurden weiterhin 1340 Transplantate aus dem Ausland importiert, und es warteten mehr als 3300 Patienten am Jahresende auf ein Hornhauttransplantat. Der Transplantatengpass ist somit noch nicht beseitigt.
Akute eosinophile Pneumonie (AEP) nach Shisha-Rauchen
Authors: Mager S. , Struss M. , Wollsching-Strobel M. , Karagiannidis C. 
Published: April 2020

ZusammenfassungEin 27-jähriger, zuvor körperlich gesunder Mann stellte sich mit akut einsetzendem thorakalem Druckgefühl, Dyspnoe, nichtproduktivem Husten und Fieber in einer zentralen Notaufnahme vor. Stunden vor Symptombeginn habe der Patient Wasserpfeife mit speziellem, in Deutschland nicht frei verkäuflichen Tabak mit der Geschmacksrichtung Minze geraucht. Bei progredienter Oxygenierungsstörung musste der Patient noch am Aufnahmetag intubiert werden. In der Computertomografie des Thorax stellten sich bilateral diffuse, infiltrative Veränderungen dar. Die bei Aufnahme durchgeführte bronchoalveoläre Lavage erbrachte den Nachweis einer ausgeprägten Eosinophilie von 69 %. Anhand der Anamnese, der Eosinophilenzahl sowie der computertomografischen Veränderungen erfolgte die Diagnosestellung einer mit Shisha-Rauchen assoziierten akuten eosinophilen Pneumonie (AEP). Nach einer Kortisonstoßtherapie und 9 Beatmungstagen konnte der Patient auf die Normalstation verlegt werden. In der ambulanten Nachsorge zeigten sich eine normale, altersentsprechende Lungenfunktion sowie ein vollständig regredienter radiologischer Befund.
Folgerung Obwohl die akute eosinophile Pneumonie (AEP) eine Rarität darstellt, ist sie eine zu berücksichtigende Differenzialdiagnose bei akut einsetzendem thorakalem Druckgefühl, Dyspnoe, nichtproduktivem Husten, Fieber und anamnestischem Wasserpfeifenkonsum. Mittels einer Kortisonstoßtherapie und Beatmung kann ein schweres ARDS bis zur vollständigen Ausheilung therapiert werden.
Cytokinesis and postabscission midbody remnants are regulated during mammalian brain development
Authors: McNeely Katrina C. , Dwyer Noelle D. 
Published: April 2020

SignificanceDuring prenatal brain development, neural stem cells must divide to produce billions of daughter cells. At early stages, they produce more stem cells. Later, they produce neurons. Errors in their divisions can result in abnormal brains. We address whether cytokinesis—cleavage furrowing and intercellular bridge severing (abscission)—occurs differently at different ages and in a small-brained mouse mutant of a kinesin motor protein gene. We developed a method to image neural stem cells undergoing cytokinesis in brain explants. We found that remnants of severed intercellular bridges are more likely to remain on daughter cells at earlier ages. In the kinesin gene mutant, bridge severing occurs faster. These findings suggest that precise regulations of cytokinesis are important during early brain development.
Do media systems matter?
Authors: Santana-Pereira José 
Published: April 2020

Abstract
This article reports a comparative analysis of the media’s political agenda setting capacity in 27 European media systems, aimed at testing the hypothesis that the magnitude of this phenomenon is moderated by factors such as development of the press markets, journalist professionalization, strength of public television or political pluralism. The empirical analysis relies on data collected by the expert survey European Media Systems Survey, the World Association of Newspapers, the European Audiovisual Observatory, and the research project Providing an Infrastructure for Research on Electoral Democracy in the European Union (PIREDEU). Results show that political agenda setting is perceived as more common in press markets in which newspapers work as means of horizontal communication (and are, as subsystem, politically imbalanced), but that journalist professionalization and strength of public broadcasting systems foster political agenda setting effects.
Political agenda-setting and -building in small consensus democracies
Authors: Sciarini Pascal , Tresch Anke , Vliegenthart Rens 
Published: April 2020

Abstract
This paper analyzes the mutual influence between media and political agendas in the Netherlands and Switzerland. While these two countries share a number of similarities, they also exhibit some important differences (e.g. the frequency of parliamentary meetings) that are likely to affect the patterns of influence. Time-series cross-section analyses of monthly data about issue attention in parliamentary questions and in media coverage for the period 1995–2003 (Switzerland) and 1995–2011 (Netherlands) provide partial support for our hypotheses. Agenda-setting and -building effects are overall stronger in Switzerland, which may be due to differences in the workings of national parliaments and varying degrees of mediatization. Moreover, our analyses reveal more pronounced differences between the coalition and opposition parties in Switzerland. Overall, this study demonstrates that it is important to consider smaller institutional differences when studying political agenda-setting and -building in a cross-national perspective.
Direct (dis)agreement verbs
Authors: Chung Siaw-Fong 
Published: April 2020

Abstract
“*I am not agree with you” is an incorrect use of agree frequently seen in the
writing of Taiwanese learners. Yet, not many studies have discussed the use of agree and
disagree in the literature. Many studies are concerned more about the politeness of (dis)agreement,
especially in detailing the relationship between speaker and hearer. We took a lexical semantic approach to compare the use of
agree and disagree in essays written by native English speakers and Taiwanese learners in
the ICNALE (International Corpus Network of Asian Learners of English). The essays were based on two topics
concerning societal issues collected in the corpus – (a) whether smoking should be completely banned in restaurants and (b)
whether college students should take a part-time job or not – the writers were asked to respond to each issue by agreeing or
disagreeing. Our results showed that when given clear instructions to agree or disagree, both native and learners tended to state
(dis)agreement in the very first sentence in their essays, but Taiwanese learners relied more on the uses of
agree and disagree more often than the native speakers did. The errors committed by learners
on the use of agree (not for disagree) were between 25–35% in our data. The results will bring
significant comparisons of the lexical semantics of related verbs (verbs of social interaction) in future studies.
Productivity and graduality in the Layered Structure of the Word
Authors: Novo Urraca Carmen , Ojanguren López Ana Elvira 
Published: April 2020

Abstract
This article deals with two theoretical aspects of lexical derivation, productivity and graduality. After a discussion of transparency and opaqueness in Old English word-formation, it focuses on lexical productivity and puts forward a typology of recursive phenomena. On the basis of this typology, the morphological template of the Layered Structure of the Word is revised. The main conclusion is that a more diachronically oriented analysis is likely to opt for a decompositional template, whereas a more synchronically directed study which seeks typological validity will probably favour the template with one functional slot. If the focus is on diachronic linguistics, a template based on minimal constituent analysis can guarantee a detailed description of the derivational steps of the word, including non-affixal derivation and semantically opaque affixes.
Simulation System of Lake Eutrophication Evolution based on RS & GIS Technology—a Case Study in Wuhan East Lake
Authors: Yang Xin , Huang Mutao , Bai Kaiyuan 
Published: April 2020

Abstract
Water is the source of life and monitoring water quality is very important. Traditional water quality monitoring often uses artificial methods, taking water samples on the spot, and then analysing them in the laboratory. This method is time-consuming and labour-intensive, and is affected by time, weather and human activities. It is not only inaccurate, but also difficult to multi-period. It is difficult to monitor large areas of water. This study proposes an intelligent water quality monitoring system— Simulation System of Lake Eutrophication Evolution based on RS & GIS Technology (SSLEE). Based on the .NET Framework, the system interface design is completed through Windows Form platform. C#, IDL and ArcGIS Engine are used to develop the whole system. The system can manage the measured data, remote sensing image data, preprocess the remote sensing image and retrieve the chlorophyll a concentration. Taking Wuhan East Lake as an example, the applicability of SSLEE system is demonstrated. Compared with the measured results, the error is small, indicating that the system is reliable in water quality monitoring of inland lakes.