bluuebunny/crossref_metadata_2025_split huggingface dataset:
IT capabilities as a fundamental of electronic government system success in developing countries from users perspectives
Authors: Alshaher Ali 
Published: November 2020

PurposeThis study aims to consider the capabilities of information technology as a basing dimension in the success of systems that provide electronic services as an e-government system. This study will focus on the role of IT capabilities in e-government system success by proposing a model based on the integration of the updated DeLone and McLean model is (D&M) with the unified theory of acceptance and use of technology is (UTAUT) model, which includes seven variables, namely, IT capabilities, information quality, system quality, performance expectancy, effort expectancy, perceived support quality and e-government system usage.Design/methodology/approachA conceptual framework was built across a review of the literature and the results of studies of IT capability and e-government systems success has developed the study model. As the causal approach was adopted to test the model of the proposed study. Survey data collected from 765 respondents who use the e-government system in Iraq. Also, a regression approach has been used to test the study model.FindingsThe results revealed that IT capabilities and the factors included in the “the updated (D&M) and (UTAUT) model” as important forecasts in the success of e-government systems. In another word, the proposed model provides managers with a new perspective to deal with the adoption of the e-government system by introducing a new variable “IT capabilities,” to provide decision-makers with a new approach in determining factors of e-government success.Research limitations/implicationsThe government must develop their policies in line with e-government services to maximize the benefits accrued from e-government services. Where the main determinants in this study were the age group of the sample and the Arab environment for this study.Originality/valueThis study is the first in Iraq as a developing country and one of the few in e-government that considers IT capabilities as a basing dimension in e-government success by proposing a comprehensive model that sums the factors related to such a relationship. Its value stems from its sample of public users and the support of its proposed framework.
Kirchhoff pre‐stack depth scalar migration in a simple triclinic velocity model for three‐component P, S1, S2 and converted waves
Authors: Bucha Václav 
Published: November 2020

ABSTRACTMigration of multi‐component elastic data in anisotropic models is difficult and has not been reasonably addressed. Thus we test three‐dimensional ray‐based Kirchhoff pre‐stack depth scalar migration and calculate migrated sections in a simple anisotropic velocity model. We generate ray‐theory seismograms for separate phases of reflected P, S1, S2 and converted waves. The velocity model is composed of two homogeneous layers and one curved interface. The anisotropy of the upper layer is triclinic and the bottom layer is isotropic. We apply a scalar imaging separately to each component of the elementary wave in a single‐layer velocity model with the same triclinic anisotropy as in the upper layer of the velocity model used to calculate the recorded wave field. Results of Kirchhoff pre‐stack depth scalar migration indicate big differences for individual elementary wave components. We observe very good migrated interface for all three components of reflected PP wave, radial component of PS1 converted wave and transversal component of PS2 converted wave. For other components and elementary waves, the migrated interface is imaged, only partially, correctly.
Rearing water microbiomes in white leg shrimp (Litopenaeus vannamei) larviculture assemble stochastically and are influenced by the microbiomes of live feed products
Authors: Heyse Jasmine , Props Ruben , Kongnuan Pantipa , De Schryver Peter , Rombaut Geert , Defoirdt Tom , Boon Nico 
Published: November 2020

SummaryThe development of effective management strategies to reduce the occurrence of diseases in aquaculture is hampered by the limited knowledge on the microbial ecology of these systems. In this study, the dynamics and dominant community assembly processes in the rearing water of Litopenaeus vannamei larviculture tanks were determined. Additionally, the contribution of peripheral microbiomes, such as those of live and dry feeds, to the rearing water microbiome were quantified. The community assembly in the hatchery rearing water over time was dominated by stochasticity, which explains the observed heterogeneity between replicate cultivations. The community undergoes two shifts that match with the dynamics of the algal abundances in the rearing water. Source tracking analysis revealed that 37% of all bacteria in the hatchery rearing water were introduced either by the live or dry feeds, or during water exchanges. The contribution of the microbiome from the algae was the largest, followed by that of the Artemia, the exchange water and the dry feeds. Our findings provide fundamental knowledge on the assembly processes and dynamics of rearing water microbiomes and illustrate the crucial role of these peripheral microbiomes in maintaining health‐promoting rearing water microbiomes.
Comparison of two vitamin D supplementation strategies in children with sickle cell disease: a randomized controlled trial
Authors: Grégoire‐Pelchat Pascale , Pastore Yves , Robitaille Nancy , LeMay Sylvie , Khamessan Ali , Kleiber Niina , Nyalendo Carine , Gagné Nancy , Alos Nathalie , Mailhot Geneviève 
Published: November 2020

SummaryPreviously, we showed that nearly 70% of children followed in our sickle cell disease (SCD) clinic were vitamin D‐ deficient and had low vitamin intake with poor use of supplements. We compared the change in serum 25‐hydroxyvitamin D [25(OH)D], safety and clinical impact of two vitamin D supplementation regimens in children with SCD. Children (5–17 years, all genotypes) were randomized to a single bolus of vitamin D3 (300 000 IU; n = 18) or placebo (n = 20). All children received a prescription for daily 1 000 IU vitamin D3. Serum 25(OH)D and calcium, urinary calcium/creatinine ratio, musculoskeletal pain, quality of life, haematology and bone markers were assessed at baseline and three months post intervention. Bolus administration led to a greater rise in 25(OH)D levels from baseline compared to placebo (20 ± 16 nmol/l vs. 2 ± 19 nmol/l; P = 0·003) and correction of vitamin D deficiency. No hypercalcaemia nor hypercalciuria occurred during the study, but more children in the bolus group experienced gastrointestinal symptoms within the first month (P = 0·04). There were no differences between groups for other outcomes. The use of a high‐dose vitamin D bolus combined with daily 1 000 IU vitamin D3 was more efficient in raising 25(OH)D levels than daily supplementation alone in children with SCD.
A BBS1 SVA F retrotransposon insertion is a frequent cause of Bardet‐Biedl syndrome
Authors: Delvallée Clarisse , Nicaise Samuel , Antin Manuela , Leuvrey Anne‐Sophie , Nourisson Elsa , Leitch Carmen C. , Kellaris Georgios , Stoetzel Corinne , Geoffroy Véronique , Scheidecker Sophie , Keren Boris , Depienne Christel , Klar Joakim , Dahl Niklas , Deleuze Jean‐François , Génin Emmanuelle , Redon Richard , Demurger Florence , Devriendt Koenraad , Mathieu‐Dramard Michèle , Poitou‐Bernert Christine , Odent Sylvie , Katsanis Nicholas , Mandel Jean‐Louis , Davis Erica E. , Dollfus Hélène , Muller Jean 
Published: November 2020

AbstractBardet‐Biedl syndrome (BBS) is a ciliopathy characterized by retinitis pigmentosa, obesity, polydactyly, cognitive impairment and renal failure. Pathogenic variants in 24 genes account for the molecular basis of >80% of cases. Toward saturated discovery of the mutational basis of the disorder, we carefully explored our cohorts and identified a hominid‐specific SINE‐R/VNTR/Alu type F (SVA‐F) insertion in exon 13 of BBS1 in eight families. In six families, the repeat insertion was found in trans with c.1169 T > G, p.Met390Arg and in two families the insertion was found in addition to other recessive BBS loci. Whole genome sequencing, de novo assembly and SNP array analysis were performed to characterize the genomic event. This insertion is extremely rare in the general population (found in 8 alleles of 8 BBS cases but not in >10 800 control individuals from gnomAD‐SV) and due to a founder effect. Its 2435 bp sequence contains hallmarks of LINE1 mediated retrotransposition. Functional studies with patient‐derived cell lines confirmed that the BBS1 SVA‐F is deleterious as evidenced by a significant depletion of both mRNA and protein levels. Such findings highlight the importance of dedicated bioinformatics pipelines to identify all types of variation.
Renal transplantation during the SARS‐CoV‐2 pandemic in the UK: Experience from a large‐volume center
Authors: Georgiades Fanourios , Summers Dominic M. , Butler Andrew J. , Russell Neil K. I. , Clatworthy Menna R. , Torpey Nicholas 
Published: November 2020

AbstractThere is uncertainty about the safety of kidney transplantation during the SARS‐CoV‐2 pandemic due to the risk of donor transmission, nosocomial infection and immunosuppression use. We describe organ donation and transplant practice in the UK and assess whether kidney transplantation conferred a substantial risk of harm. Data from the UK transplant registry were used to describe kidney donation and transplant activity in the UK, and a detailed analysis of short‐term, single‐center, patient results in two periods: during the pre‐pandemic era from 30th December 2019 to 8th March 2020 (“Pre‐COVID era”) and the 9th March 2020 to 19th May 2020 (“COVID era”). Donor and recipient numbers fell by more than half in the COVID compared to the pre‐COVID era in the UK, but there were more kidney transplants performed in our center (42 vs. 29 COVID vs. pre‐COVID respectively). Overall outcomes, including re‐operation, delayed graft function, primary non‐function, acute rejection, length of stay and graft survival were similar between COVID and pre‐COVID era. 6/71 patients became infected with SARS‐CoV‐2 but all were discharged without critical care requirement. Transplant outcomes have remained similar within the COVID period and no serious sequelae of SARS‐CoV‐2 infection were observed in the peri‐transplant period.
Purchasing, consumption, demographic and socioeconomic variables associated with shifts in alcohol consumption during the COVID‐19 pandemic
Authors: Callinan Sarah , Mojica‐Perez Yvette , Wright Cassandra J. C. , Livingston Michael , Kuntsche Sandra , Laslett Anne‐Marie , Room Robin , Kuntsche Emmanuel 
Published: November 2020

AbstractIntroduction and AimsRestrictions introduced to reduce the spread of COVID‐19 have had major impacts on the living circumstances of Australians. This paper aims to provide insight into shifts in alcohol consumption and associated factors during the epidemic.Design and MethodsA cross‐sectional convenience sample of 2307 Australians aged 18 and over who drank at least monthly was recruited through social media. Respondents were asked about their alcohol consumption and purchasing in 2019 prior to the epidemic plus similar questions about their experiences in the month prior to being surveyed between 29 April and 16 May 2020.ResultsReports of average consumption before (3.53 drinks per day [3.36, 3.71 95% confidence interval]) and during (3.52 [3.34, 3.69]) the pandemic were stable. However, young men and those who drank more outside the home in 2019 reported decreased consumption during the pandemic, and people with high levels of stress and those who bulk‐bought alcohol when restrictions were announced reported an increase in consumption relative to those who did not.Discussion and ConclusionsA reported increase in consumption among those experiencing more stress suggests that some people may have been drinking to cope during the epidemic. Conversely, the reported decrease in consumption among those who drank more outside of their home in 2019 suggests that closing all on‐trade sales did not result in complete substitution of on‐premise drinking with home drinking in this group. Monitoring of relevant subgroups to assess long‐term changes in consumption in the aftermath of the epidemic is recommended.
Prevalence of obesity and disturbances in glucose homeostasis in HIV‐infected subjects and general population – missed diagnoses of diabetes?
Authors: Hanttu A , Kauppinen KJ , Kivelä P , Ollgren J , Jousilahti P , Liitsola K , Koponen P , Sutinen J 
Published: November 2020

ObjectivesComparative data on glucose disorders using fasting blood samples between people living with HIV (PLWH) and the general population are lacking. The objective of this study was to compare the prevalence and risk factors of obesity and disturbances in glucose homeostasis between PLWH treated with modern antiretroviral therapy and the general population.MethodsAdjusted prevalence of obesity, features of insulin resistance (triglyceride:high‐density lipoprotein cholesterol ratio and alanine aminotransferase), impaired fasting glucose (IFG), diabetes mellitus (DM) and combined dysglycaemia (presence of IFG or DM) were determined using fasting blood samples among 1041 PLWH and 7047 subjects representing the general population.ResultsPeople living with HIV had a lower prevalence of obesity [18.2%, 95% confidence interval (CI): 15.1–21.2 vs. 23.9%, 95% CI: 22.4–25.4], but a higher prevalence of insulin resistance and IFG (20.0%, 95% CI: 16.6–23.4 vs. 9.8%, 95% CI: 8.7–10.8) than the general population. Fasting glucose concentration was higher, but glycated haemoglobin (HbA1c) was lower, among PLWH. Prevalence of dysglycaemia for a given body mass index (BMI) was higher in PLWH than in the general population. The prevalence of DM did not differ between PLWH (13.2%, 95% CI: 10.2–15.9) and the general population (14.5%, 95% CI: 13.6–15.4).ConclusionsThe prevalence of obesity was lower, but the risk of dysglycaemia for a given BMI was significantly higher, among PLWH, highlighting the importance of prevention and treatment of obesity among HIV‐infected subjects. Regardless of the increased prevalence of insulin resistance and IFG, DM was surprisingly not more common among PLWH, raising concern about the under‐diagnosis of DM, possibly due to low sensitivity of HbA1c in this patient population.
Guidelines for reporting on CBCT scans
Authors: Patel S. , Harvey S. 
Published: November 2020

AbstractThe aim of a radiographic report is to provide an accurate interpretation of images to facilitate the diagnostic process, and when indicated prompt the appropriate management for the patient. It is part of the patient’s clinical records. This paper describes the imaging chain involved in the cone beam computed tomography (CBCT) workflow from referring to reporting on a CBCT scan. It provides guidelines on the essential information required before and immediately after a CBCT scan is taken, and optimizing the viewing conditions. Finally, it describes a framework for a systematic, comprehensive and tailored CBCT radiographic report. It is aimed at endodontists, clinicians and radiologists reporting on CBCT scans of the dentoalveolar region.
Effect of medium condition change on green body density during casting and drying
Authors: Iwata Naoya , Yamada Saori , Mori Takamasa 
Published: November 2020

AbstractThe present study examined whether the optimum slurry conditions in which the green body with the highest packing fraction was fabricated were the same regardless of whether tape or slip casting methods were used. Additionally, we investigated the optimum slurry evaluation method to predict the packing fraction of each green body. Specifically, aqueous dense alumina slurries, whose particle dispersion state was changed by varying pH and the amount of dispersant additive, were prepared. After changing the pH, the optimum slurry conditions were achieved regardless of the casting method. The most suitable amount of additive dispersant differed due to the changing solution conditions during the casting and drying process; the medium of the slurry permeated into the plaster during slip casting and dried on the substrate during tape casting. Thus, in slip casting, non‐adsorbed polymers could also be permeated. Hence, it is crucial for slurry evaluation to predict the packing fraction of the slip cast body. A sedimentation test, which involved particle condensation as well as casting, was valid for the green sheet. Conversely, it was experimentally shown that the constant pressure filtration test, which involved the permeation of the medium in addition to particle condensation, was suitable for slip casting.
Effectiveness and adverse effects of at‐home dental bleaching with 37% versus 10% carbamide peroxide: A randomized, blind clinical trial
Authors: Sutil Elisama , da Silva Karine Letícia , Terra Renata Maria Oleniki , Burey Adrieli , Rezende Márcia , Reis Alessandra , Loguercio Alessandro D. 
Published: November 2020

AbstractPurposeThe aim of this trial was to evaluate bleaching effectiveness, tooth sensitivity and gingival irritation of whitening patients with 10% versus 37% carbamide peroxide (CP).MethodsEighty patients were selected by inclusion and exclusion criteria and randomly allocated into two groups (n = 40): 37% CP and 10% CP. In both groups, patients performed whitening for 3 weeks, 4 h/day for 10% group and 30 min/day for 37% group. Color was evaluated with Vita Classical, Vita Bleachedguide 3D Master and Spectrophotometer Easyshade, at baseline, weekly and 30 days after treatment. Absolute risk and intensity of tooth sensitivity (TS) and gingival irritation (GI) were assessed with numeric rating scale (NRS) and a visual analog scale (VAS). Color changes were compared with t‐test for independent samples. TS and GI were evaluated with Fisher's exact tests. Mann–Whitney test was used for NRS, and t‐tests for VAS (α = 0.05).ResultsThe 37% CP group showed faster whitening than 10% group at 1–3 weeks. However, 1 month after conclusion, both groups showed equivalent bleaching (p = 0.06). Regarding sensitivity and gingival irritation, 10% and 37% groups met no significant differences (p > 0.05).ConclusionThe use of 37% CP 30 min/day showed equivalent results to 10% 4 h/day.Clinical significanceThe use of 37% carbamide peroxide 30 min/day may decrease the time of tray use in at‐home protocol for whitening because it presents equivalent results to 10% carbamide peroxide 4 h/day.
A study using semi‐structured interview and Delphi survey to explore the barriers and enabling factors that influence access and utilisation of weight management services for people living with morbid obesity: A patient and professional perspective
Authors: Holt Guy , Hughes David 
Published: November 2020

AbstractBackgroundA quarter of the United Kingdom’s population are living with obesity, a disease that causes an estimated 30 000 deaths each year. This coincides with an under‐utilisation of weight management services across the country with the majority of patients with morbid obesity having no record of any weight loss intervention at all. This study explores the factors that influence patient access to weight management services.MethodologyExpert opinion was obtained using semi‐structured interviews and the Delphi methodology. Participants were selected from primary and secondary healthcare settings. Healthcare professionals (HCPs) had experience working in weight management services or in services dealing with obesity‐related comorbidities. Patients had experience in attending a variety weight management services.ResultsNineteen participants completed all aspects of the study. The main barriers included negative perceptions, low mood/depression, obesity not being considered as a serious disease, lack of access to services for housebound patients and disproportionate commissioning. Suggested facilitating factors to improve access included the education of all HCPs about obesity, improving HCP communication with patients, and broadening the number of HCP’s that are able to refer to weight management services.ConclusionsFuture services must prioritise the education of all HCPs and the public to combat the stigma of obesity and its impact on health. National commissioning guidelines in partnership with advocates of obesity should seek to streamline referral pathways, broaden referral sources and increase the availability of specialist services. Awareness of these factors when designing future weight management services will help to improve their utilisation.
Blood transfusion‐induced posterior reversible encephalopathy syndrome with periodic sharp wave complexes, 14‐3‐3 protein elevation, and the pulvinar sign
Authors: Shiraishi Wataru , Yamaguchi Takahiro , Fujiki Ryosuke , Furuta Konosuke 
Published: November 2020

AbstractA 52‐year‐old Japanese woman was admitted to our hospital with consciousness disturbance and convulsions at 10 days after transfusion with 10 U of blood due to severe anemia. Electroencephalography showed periodic sharp wave complexes, cerebrospinal fluid 14‐3‐3 protein levels were elevated, and brain magnetic resonance imaging demonstrated bilateral thalamic hyperintensity. These findings suggested Creutzfeldt‐Jakob disease (CJD); however, her symptoms were resolved with antiepileptic and anti‐hypertensive drugs. We herein report a case of posterior reversible encephalopathy syndrome that occurred after a blood transfusion who showed features compatible with CJD.
Validation and psychometric evaluation of the Spanish version of Brief Esophageal Dysphagia Questionnaire (BEDQ): Results of a multicentric study
Authors: Cisternas Daniel , Taft Tiffany , Carlson Dustin A. , Glasinovic Esteban , Monrroy Hugo , Rey Paula , Hani Albis , Ardila‐Hani Andres , Leguizamo Ana Maria , Bilder Claudio , Ditaranto Andres , Varela Amanda , Agotegaray Joaquin , Remes‐Troche Jose Maria , Ruiz de León Antonio , Pérez de la Serna Julio , Marin Ingrid , Serra Jordi 
Published: November 2020

AbstractBackgroundThe recently developed Brief Esophageal Dysphagia Questionnaire (BEDQ) evaluates esophageal obstructive symptoms. Its initial evaluation showed strong psychometric properties. The aims of this study were to (a) translate and validate an international Spanish version of BEDQ and (b) evaluate its psychometric properties in a large Hispano‐American sample of symptomatic individuals.MethodsA Spanish BEDQ version was performed by Hispano‐American experts using a Delphi process and reverse translation. Patients were prospectively recruited from seven centers in Spain and Latin America among individuals referred for high‐resolution manometry (HRM). Patients completed several scores: Hospital Anxiety & Depression Scale (HADS), Eckardt score (ES), Gastroesophageal Reflux Questionnaire (GERDQ), and the BEDQ. Standardized psychometric analyses were performed.Key ResultsA total of 426 patients were recruited. Spanish BEDQ showed excellent reliability (Cronbach's alpha = 0.91). Factor analysis confirmed its unidimensional character. Moderate significant correlations between BEDQ and other symptomatic scores were found, suggesting sufficient convergent validity. Patients with abnormal or obstructive HRM findings scored significantly higher when compared to normal or non‐obstructive findings, respectively. Using a cutoff of 10, BEDQ showed a sensitivity of 65.38% and a specificity of 66.21% and an area under the curve of 0.71 for obstructive or major manometric diagnosis.Conclusions and InferencesA widely usable Spanish BEDQ version has been validated. We confirm its excellent psychometric properties in our patients, confirming the appropriateness of its use in different populations.