bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prioritizing Factors Affecting Health Service Quality using Integrated Fuzzy DEMATEL and ANP: A Case of Iran
Authors: Farhadi Payam , Niyas Maryam , Shokrpour Nasrin , Ravangard Ramin 
Published: June 2020

Background:Quality of services is one of the important factors affecting the success of service organizations. However, due to limited resources, organizations should identify the most important dimensions of service quality and take some measures to improve them.Objective:To identify and prioritize the factors affecting service quality from the viewpoints of all health care stakeholders in the teaching hospitals and the headquarters affiliated to Shiraz University of Medical Sciences.Methods:This is an applied, cross-sectional and descriptive-analytical study conducted in the teaching hospitals and the headquarters affiliated to Shiraz University of Medical Sciences. The study population consisted of all health care stakeholders, including patients, patients' families and relatives, general population, health care policymakers and managers, and health service providers such as matrons and supervisors. Six people of each studied stakeholder group were selected as the study sample using a purposive sampling method (n=30). A pair-wise comparison matrix designed based on the SERVQUAL dimensions was used for making pair-wise comparisons and collecting the required data. The collected pair-wise comparison data were analyzed through Fuzzy DEMATEL and ANP techniques using Super Decision 2.2 and Excel 2007.Results:The results showed that Access (NW=0.39018) and Tangibility (NW=0.05873) had the highest and lowest priorities.Conclusion:According to the results of the present study and from the studied health care stakeholders' viewpoint, access to care was the most affecting and most important dimension to be improved. Therefore, in order to improve patients' access to the health care services, some suggestions can be made such as providing appropriate facilities for patients' families and relatives, offering special discounts to the poor, providing easier access to the emergency entrance, providing parking and accommodation for patients and their relatives, employing and using the appropriate number of staff, and delivering 24-hour and high-quality health care services.
Chemical Composition and Antifungal Effects of Nectaroscordum Tripedale Extract Against Some of Pathogenic Yeast Strains
Authors: Jahanbakhsh Sareh , Ebrahimi Katrin , Sepahvand Maryam , Niazi Massumeh , Yari Fatemeh , Shakarami Amir , Tarhani Fariba , Kharazi Sam 
Published: June 2020

Background:Several drugs are currently in use to treat fungal infections; however, recent studies indicate that the consumption of these drugs is associated with serious complications. This study was done to examine the chemical composition and antifungal effects of Nectaroscordum tripedale against several yeast strains.Methods:The antifungal activity of N. tripedale extract on Saccharomyces cerevisiae and Candida albicans, C. glabrata was examined via the assessment of minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) according to the broth micro dilution technique (M27-A3 protocol). By means of gas chromatography/mass spectroscopy (GC/MS), the major constituents of this extract were identified.Results:The findings exhibited that N. tripedale extract represents not only fungistatic but also fungicidal activity with an average MIC and MFC of 12.5 to 66.6 μg/ml, respectively, for tested yeasts. The results also demonstrated that decadienal (11.1%), hexadecanoic acid (10.3%), and heptadecane (9.5%), were the major constituents of this extract.Conclusion:The findings demonstrated the preliminary anti-yeast effects of this plant and suggest the use of N. tripedale for yeast infections in the traditional medicine. This study for the first time showed N. tripedale as a new antifungal patent to treat the candidiasis and other yeast infections; however, more studies are required to assess the precise anti-candida effects of this plant against other Candida spp. as well as in human subjects.
Application of Nanotechnology to the Extraction of Herbal Components for Medicinal Uses
Authors: Salunkhe Pratibha , Bhoyar Priya , Gode Amravati , Shewale Sandeep P. 
Published: June 2020

:
Herbal medicine is central to Indian medicinal treatment, which has been
known as Ayurveda traditionally. There are hundreds of herbs that have the
qualities to treat several kinds of diseases, even critical and chronic ones.
Importantly, these herbs have hardly any side effects. Herbal medicine is
manufactured from herbal extracts. Hence, the method of extracting herbal extracts
assumes high importance in manufacturing herbal medicines.

:
There are several methods for extracting herbs. However, the novel drug delivery
system (NDDS)-nanotechnology has been gaining popularity as a method to extract
herbal extracts. NDDS offers miraculous promises as it is a complete processing
system that combines the methods of drug formulation (pharmaceutics),
biochemistry, molecular biology, and process and technology. In this method, a
nano-sized drug release system is used to transmit medicines on the targeted parts
of the human body safely. NDDS serves many purposes, such as it minimizes the
requirement of frequent supervision to conquer refusal, enhances the remedial
worth, minimizes toxicity, and rises bioavailability.

:
There are many advantages to the targeted drug release system, such as it reduces
the frequency of the dosages taken by the patients, has a more uniformed effect of
the drug, reduces any possibility of side effects, and controls fluctuation in
circulating drug levels.
Structural Basis for Designing Multiepitope Vaccines Against COVID-19 Infection: In Silico Vaccine Design and Validation
Authors: Srivastava Sukrit , Verma Sonia , Kamthania Mohit , Kaur Rupinder , Badyal Ruchi Kiran , Saxena Ajay Kumar , Shin Ho-Joon , Kolbe Michael , Pandey Kailash C 
Published: June 2020

Background
The novel coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to the ongoing 2019-2020 pandemic. SARS-CoV-2 is a positive-sense single-stranded RNA coronavirus. Effective countermeasures against SARS-CoV-2 infection require the design and development of specific and effective vaccine candidates.

Objective
To address the urgent need for a SARS-CoV-2 vaccine, in the present study, we designed and validated one cytotoxic T lymphocyte (CTL) and one helper T lymphocyte (HTL) multi-epitope vaccine (MEV) against SARS-CoV-2 using various in silico methods.

Methods
Both designed MEVs are composed of CTL and HTL epitopes screened from 11 structural and nonstructural proteins of the SARS-CoV-2 proteome. Both MEVs also carry potential B-cell linear and discontinuous epitopes as well as interferon gamma–inducing epitopes. To enhance the immune response of our vaccine design, truncated (residues 10-153) Onchocerca volvulus activation-associated secreted protein-1 was used as an adjuvant at the N termini of both MEVs. The tertiary models for both the designed MEVs were generated, refined, and further analyzed for stable molecular interaction with toll-like receptor 3. Codon-biased complementary DNA (cDNA) was generated for both MEVs and analyzed in silico for high level expression in a mammalian (human) host cell line.

Results
In the present study, we screened and shortlisted 38 CTL, 33 HTL, and 12 B cell epitopes from the 11 protein sequences of the SARS-CoV-2 proteome. Moreover, the molecular interactions of the screened epitopes with their respective human leukocyte antigen allele binders and the transporter associated with antigen processing (TAP) complex were positively validated. The shortlisted screened epitopes were utilized to design two novel MEVs against SARS-CoV-2. Further molecular models of both MEVs were prepared, and their stable molecular interactions with toll-like receptor 3 were positively validated. The codon-optimized cDNAs of both MEVs were also positively analyzed for high levels of overexpression in a human cell line.

Conclusions
The present study is highly significant in terms of the molecular design of prospective CTL and HTL vaccines against SARS-CoV-2 infection with potential to elicit cellular and humoral immune responses. The epitopes of the designed MEVs are predicted to cover the large human population worldwide (96.10%). Hence, both designed MEVs could be tried in vivo as potential vaccine candidates against SARS-CoV-2.
Resistências urbanas e sua conjunção em rede
Authors: Carvalho Liliane Katita , Imbrunito Maria Isabel 
Published: June 2020

Este artigo busca reconhecer as ações coletivas de caráter tático desenvolvidas no Distrito de São Mateus, localizado na periferia leste do município de São Paulo, entendendo-as como resistências urbanas. Busca-se identificar suas articulações, seu processo de organização em rede, além do impacto promovido na gestão territorial da área analisada. Objetiva-se relacionar a ação tática e sua convergência organizacional junto a aspectos estruturais das chamadas redes complexas. Para isso, realizou-se o mapeamento dos coletivos que desenvolveram ações entre 2016 e 2018, identificando suas perspectivas e expressões no território. As ações desenvolvidas foram acompanhadas e registradas a fim de se obter dados para a produção de mapeamentos e análise do grau de intervenção no espaço urbano. Observou-se o desenvolvimento do que denominou-se neste artigo como “rede tática”, considerando os aspectos das ações desenvolvidas no distrito e seu fortalecimento a partir da estruturação em rede. Desse modo, demonstra-se o potencial das ações táticas na transformação do território e, por consequência, na construção de novas formas de gestão e planejamento urbano.
Elderly people at village level in Botswana
Authors: Ingstad Benedicte , Brunborg Helge , Bruun Frank J. 
Published: June 2020

The paper presents demographic and social data from an in-depth study of the situation of elderly people in a village in Botswana. Botswana is undergoing rapid economic and social change and this change also affects the elderly part of the population. While younger people migrate to urban areas, the elderly are to a large extent left behind in the villages, often with responsibility for caring tor small grandchildren. We found that the majority of elderly people in the study village are women. The educational level of the elderly people of both sexes is low but the majority have undergone the traditional initiation schools, Bojale and Bogwera. All households are influenced by modernization in that they need cash for survival. They depend to a large extent on the support of their grandchildren for survival, a support which is not always given.
Gestão de Stakeholders: Estado da Arte e Perspectivas
Authors: Mascena Keysa Manuela Cunha de , Stocker Fabricio 
Published: June 2020

Objetivo: a pesquisa tem como objetivo apresentar um panorama dos estudos sobre gestão de stakeholders, revisando os principais modelos e proposições teóricas e investigando os fenômenos abordados nos artigos empíricos da temática.Método: Empreendeu-se um levantamento bibliométrico e análise sociométrica das publicações internacionais e nacionais relacionadas ao tema entre 1980 e 2019.Originalidade/Relevância: a abordagem de stakeholders tem se desenvolvido nos últimos anos e sua aplicação está cada vez mais presente em diversas áreas de gestão, tendo uma forte interlocução nas questões emergentes da sociedade. Este estudo tem uma relevância acadêmica ao avançar na disseminação do conhecimento atual da teoria de stakeholders integrando aos estudos empíricos da temática.Resultados: os resultados foram discutidos de modo a analisar: as variáveis relacionadas à gestão de stakeholders; os modelos de gestão de stakeholders aplicados nos estudos empíricos; os principais resultados nos estudos sobre conflito de interesses de stakeholders; e discussões sobre a influência e pressões dos stakeholders.Contribuições teóricas: a contribuição da pesquisa consiste na elaboração de um panorama da gestão de stakeholders, apresentando as principais contribuições teóricas e empíricas, e as dimensões para perspectivas estudos futuros, sendo: i) criação, cocriação e distribuição de valor; ii) cooperação, envolvimento e engajamento de stakeholders; iii) influência da gestão de stakeholders no desempenho; e iv) networks, relacionamentos e influência de múltiplos stakeholders.
Pengembangan Kompetensi Guru dalam Pembelajaran Berbasis Budaya: Culturally Responsive Transformative Teaching (CRTT)
Authors: Rahmawati Yuli , Ridwan Achmad , Agustin Mega Ayu 
Published: June 2020

Artikel ini merupakan hasil dari kegiatan pengabdian masyarakat yang bertujuan untuk mengembangkan kompetensi guru dalam pembelajaran berbasis budaya yaitu Culturally Responsive Transformative Teaching (CRTT). Workshop ini dapat menjadi salah satu solusi yang dapat membantu guru dalam menjawab tantangan yang diberikan oleh kurikulum 2013, terkait pengembangan nilai-nilai karakter dan budaya. Pelaksanan pengabdian masyarakat dilakukan di dua sekolah islam terpadu di Banten yaitu di Sekolah Islam Terpadu Bina Insani dan SDIT Ibadurrahman. Jumlah guru yang terlibat sebanyak 58 guru, Sekolah Islam Terpadu Bina Insani (37 orang) dan SDIT Ibadurrahman sebanyak (21 orang). Kegiatan workshop dilaksanakan dalam empat tahap, yaitu pemberian framework, integrasi budaya dalam mata pelajaran yang diampu, perancangan pembelajaran, dan presentasi hasil. Model pembelajaran dengan pendekatan CRTT diterapkan dengan lima tahapan yaitu self identification, cultural understanding, collaboration, critical reflections, transformative construction. Pengumpulan data dilakukan dengan wawancara informal dan reflektif jurnal. Analisis data dilakukan dengan analisis tema dan dipresentasikan sesuai pendapat guru secara deskripsi dan naratif. Hasil kegiatan menunjukkan guru dapat melakukan integrasi budaya Banten dalam berbagai mata pelajaran serta merencanakan pembelajaran. Di samping itu, kegiatan workhop telah mengembangkan keterampilan berpikir kritis, bekerja sama, dan rasa ingin tahu. Model pembelajaran dapat membantu guru dalam pengembangan identitas budaya dan karakter yang sejalan dengan kurikulum.
Identifying Electrocardiogram Pattern Changes and Their Association with Echocardiography among Malaysian Footballers Attending PreParticipation Evaluation
Authors: Ariffin Farnaza , Khir Rizmy Najme , Mohamed Yassin Mohamed Syarif , Baharudin Noorhida , Ismail Ilham Ameera , Abdul Hamid Hasidah , Abd Halim Haizlene 
Published: June 2020

Introduction: Sudden cardiac death is the most common medical cause of death in athletes. The aim of this study was to identify the electrocardiogram (ECG) pattern changes and its association with echocardiography among Malaysian footballers during a pre-participation evaluation (PPE). Methods: A retrospective study was conducted on footballers attending a PPE at a primary care centre. Secondary data collection was conducted and the proforma included clinical history, physical examination, ECG, Echocardiogram and cardiovascular riskfactors assessment such as heart rate, blood pressure, lipid profile, fasting blood sugar and creatinine. Data were extracted from the medical records, echocardiogram report and the original ECG. The ECG patterns were analysed according to the International consensus for ECG interpretation in athletes to determine physiological versus pathological changes. The data was analysed using SPSS v24. Results: This study included 85 male Malaysian footballers with a mean age of 20.1 ± 3.0 years. The mean resting heart rate was 55.2 ± 9.3beats per minute. Abnormal ECG changes were found in 20% of the participants, which were higher compared to that reported in other studies (14% – 17.3%). The normal ECG findings in athletes were sinus bradycardia (76.5%), J-point elevation (68.2%), prolonged PR interval (3.5%) and incomplete right bundle branch block (4.7%). The abnormal ECG changes were multiple T wave inversions (5.9%), hypertrophy (2.4%), and deep Q-waves (8.2%). Four abnormal ECGs were consistent with abnormal echocardiography findings and out of these,two ECGs with hypertrophic changes were consistent with mild inter atrial septal bulging and apical hypertrophy. Conclusions: Malaysian footballers have ECG changes that are consistent with physiological changes in athlete’s heart. The positive association between ECG and Echocardiogram findings are useful in confirming pathological ECG changes. Physicians should be trained in PPE protocol and ECG interpretation in athletes in order to improve identification of those at risk of sudden cardiac death.
Distortions of Political Regime as a Factor of Receding Democracy in Brazil
Authors: Moisés J. Á. 
Published: June 2020

Introduction. This paper represents the changes which has brought in new changed ground realities. Lot of new developments have started taking place, ever since the advent of coronavirus. The author is neither a soothsayer nor an astrologer who can adequately predict the coming future. However, at the time of writing, some broad trends are emerging on the horizon, which could impact the evolution of a new world order in cyberspace. These emerging trends are beginning to point in the direction of an irreversible change in cyberspace.Materials and methods. The methodological basis of the study was made up of following general scientific and special methods of cognition of legal phenomena and processes in the field of Cyber law, Cybercrime & cybersecurity during corona virus age: a system-structural analysis method; method of synthesis of social and legal phenomena; comparative legal method; and formal logical method.The results of the study. The analysis revealed that, the Cyberspace is full of so much of information and misinformation that people are clueless as to which information source they should rely upon and which they should not. In this pandemonium, that exist across the world, some broad new areas are emerging which are engaging the attention of numerous stakeholders.Discussion and conclusions. In today’s Coronavirus times, nothing can be predicted as absolute. However, if one keeps in mind the broad trends on the horizon, one could potentially be more well equipped to deal with challenges concerning the new cyber world order. The New Cyber World Order will be increasingly important for all digital and cyber stakeholders, as it will impact all our digital presence, digital activities and digital lives. The legal, policy and regulatory issues pertaining to New Cyber World Order will have to be appropriately considered and addressed by cyber stakeholders as New Cyber World Order takes root in the coming times.
Morals and Politics: Are These Two Things Compatible in Russia?
Authors: Yengibaryan R. V. 
Published: June 2020

Can moral policy be practiced in present-day Russia?Let’s get started start with another issue as to whether something the like of the Watergate scan- dal that went down in history books as the study in political vice might be the case on the Russian political scene? Of course, it might. According to the Russian code of political conduct, listening in on opponents is neither a crime, nor even a mis- demeanor, rather possibly or as the case may be is a necessary trick in the political process. Russian politics has never been, nor it is today part of the public and, therefore, legal domain...
The Impact of External Risks on Ensuring the Financial and Economic Security of the Russian Federation
Authors: Aminova E. M. 
Published: June 2020

Introduction. The article discusses the impact of financial risks on the financial and economic security of the state. In modern economies, the financial sector dominates the economy. Moreover, the development of financial markets has been seen in the past two decades as an independent driver of economic growth. At the same time, “negative processes that occur in a small number of financial market players in one country can cause crisis events throughout the world economy.” Among the main strategic risks and threats to national security in the economic sphere are the low stability and security of the national financial system.Materials and methods. The work uses the following general scientific and special methods of cognition: the method of system-structural analysis, synthesis, induction, deduction, comparative-legal and formal-legal method.Results. As the experience of the last decade shows, the financial and economic security of the Russian state is more influenced by the environmental factors (general economic crisis, geopolitical situation, inflation, payment crisis, climate and biological (epidemiological) risks, etc. The state governance of ensuring financial and economic security should be a permanent, integrated part of the forming process of state economic policy and legal regulation of russian economy. In order to achieve financial and economic security it is necessary to establish an effective financial and legal mechanism capable to resist emerging risks.Discussion and conclusion. The article revealed the impact of external financial risks that have a significant impact on the financial and economic security of the state. The need to establish an effective state mechanism to ensure the financial security of the Russian Federation is justified. The proposed measures are directed to improve the legal provision of financial and economic security of the Russian Federation.
Preservation and Promotion of the Traditional Chèo in Vietnam Today
Authors: Cuong Le Tuan 
Published: June 2020

Chèo is a form of traditional folk art performance of Vietnam, originated about 10 centuries ago. Cheo derives from folk music and dance, especially parody. This form is the result of artistic creation of Vietnamese peasants in northern Vietnam to Nghe An and Ha Tinh. Since its introduction, Cheo has received the attention and love among people of all classes for centuries. Quan Am Thi Kinh, Luu Binh Duong Le, Truong Vien and Kim Nham together with famous chiếng chèo: chiếng chèo Doai, chiếng chèo Bac, chiếng chèo Dong, etc. showed intense vitality and the spread of Chèo. However, along with the history of national struggle, innovation, socio-economic development, especially international integration, many new types of culture have been introduced to Vietnam while traditional art has not caught up and met the requirements of the public. It has directly contributed to weakening the values ​​of traditional culture in general and folk art including Chèo in particular. By analyzing historical and cultural documents, the article focuses on the process of formation and development of Vietnamese Chèo in history, from which to look at the contemporary of this art form and propose measures for preservation and promotion.
PENGARUH PELAYANAN ACCOUNT REPRESENTATIVE (AR) TERHADAP KEPATUHAN WAJIB PAJAK
Authors: Widayati Isro Ani , Adjis Dafina Oktavia Kartika 
Published: June 2020

Penelitian ini bertujuan untuk mengetahui pengaruh antara Pelayanan Account Representative (AR) terhadap Kepatuhan Wajib Pajak. Dalam penelitian ini Pelayanan Account Representative (AR) sebagai variable independen, sedangkan Kepatuhan Wajib Pajak sebagai variable dependen.Penelitian ini dilakukan dengan metode incidental sampling (Sampling Insidental) dengan sampel sebanyak 96 responden dari wajib pajak yang terdaftardi KPP Pratama Pajak Sawahan Surabaya. Data yang digunakan adalah data primer melalui kuesioner yang berisi jawaban-jawaban responden. Kuesioner yang terkumpul kemudian dianalisis menggunakan program SPSS (Statistical Product and Service Solution) Versi 20. Data diambil kemudian dianalisis dengan menggunakan regresi linear sederhana. Dari hasilanalisis dapat disimpulkan bahwa Pelayanan Account Representative berpengaruh secara signifikan terhadap Kepatuhan Wajib pajak pada KPP Pratama Pajak Sawahan Surabaya. Kata Kunci :Account Representative (AR) danKepatuhanWajib Pajak