bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does a preoperative Cone Beam CT reduce complication rates in the surgical removal of complex lower third molars? A retrospective study including 486 cases.
Authors: Klatt Jan , Sorowka Tony , Kluwe Lan , Smeets Ralf , Gosau Martin , Hanken Henning 
Published: December 2020

Abstract
Backround This study was designed to analyse the value of preoperative Cone Beam CTs (CBCT) prior to the surgical removal of complex lower third molars. Furthermore, the aim was to assess injuries to the inferior alveolar nerve (IAN) bundle and postoperative neurological disorders depending on the position of the lower third molar and the inferior alveolar nerve bundle.Methods In this retrospective examination preoperative Cone Beam CTs and Orthopantomographs (OPT) of 324 patients were analysed concerning the location of the lower third molars in relation to the mandible and the inferior alveolar nerve bundle. Surgery protocols of all patients who underwent the surgical removal of at least one complex lower third molar were analysed concerning patient data, length of surgery, intraoperative haemorrhage, intraoperative exposure of the inferior alveolar nerve bundle, postoperative swelling and postoperative neurological disorders. The data was then compared to data from international studies. Results In all 324 patients a permanent neurological damage was not found. Temporary neurological damage was recorded in 13 cases (2.6%). A caudal nerve position with no measurable distance to the root of the lower third molar was associated with the highest risk of a temporal neurological damage. A vestibular touching nerve route also correlated with postoperative sensitivity impairment. If a mesioangulation (Winter) or a Pell and Gregory Type IIIC appears in the OPT, risk of neurological damage is at its highest.Conclusions Three-dimensional radiographic imaging, in our patient group, does not significantly affect the risk for complications during the surgical removal of complex lower third molars. Therefore, it should only be utilized for risk assessment, especially in cases of symptom-free lower third molars.A preoperative orthopantomogram still can be accepted as standard for radiographic imaging. An intraoperative exposure of the IAN bundle does not necessarily predict simultaneous neurological damage. Exposure of the IAN bundle is no indication for a discontinuation of the surgery.
Repeat pulmonary resection for lung malignancies does not affect the postoperative complications: a retrospective study
Authors: Motono Nozomu , Iwai Shun , Iijima Yoshihito , Usuda Katsuo , Uramoto Hidetaka 
Published: December 2020

Abstract
Background: Although repeat pulmonary resection (RPR) for multiple lung cancer (MLC) has been performed for non-small cell lung cancer (NSCLC) and metastatic lung tumor, with the prognostic benefit detailed in several reports, the risk of RPR has not been well analyzed.Methods: Patients with lung malignancies who underwent complete resection at Kanazawa Medical University between January 2010 and October 2019 were analyzed. The relationship between postoperative complications and preoperative and perioperative factors was analyzed. Postoperative complications were categorized into five grades according to the Clavien–Dindo classification system.Results: A total of 41 patients who were received RPR were enrolled in this study. Primary lung tumor was found in 31 patients, and metastatic lung tumor was found in 10 patients. The postoperative complication rate of the first operation was 29%, and that of the second operation was 29%. While there were no significant factors for an increased incidence of postoperative complication in a multivariate analysis, an operation time over 2 h at the second operation tended to affect the incidence of postoperative complication (p=0.06). Furthermore, the operation time was significantly longer (p=0.02) and wound length tended to be longer (p=0.07) in the ipsilateral group than in the contralateral group. The rate of postoperative complications and the length of the postoperative hospital stay were not significantly different between the two groups.Conclusion: RPR is safely feasible and is not associated with an increased rate of postoperative complications, even on the ipsilateral side.
Decomposition and stabilization of organic matter in an old-growth tropical riparian forest: effects of soil properties and vegetation structure
Authors: Fernandes Pedro , Souza Andrea Teixeira , Tanaka Marcel , Sebastiani Renata 
Published: December 2020

Abstract
Background: Nutrient cycling in tropical forests has a large importance for primary productivity, and decomposition of litterfall is a major process influencing nutrient balance in forest soils. Although large-scale factors strongly influence decomposition patterns, small-scale factors can have major influences, especially in old-growth forests that have high structural complexity and strong plant-soil correlations. Here we evaluated the effects of forest structure and soil properties on decomposition rates and stabilization of soil organic matter using the Tea Bag Index in an old-growth riparian forest in southeastern Brazil. These data sets were described separately using Principal Components Analysis (PCA). The main axes for each analysis, together with soil physical properties (clay content and soil moisture), were used to construct structural equations models that evaluated the different parameters of the TBI, decomposition rates and stabilization factor. The best model was selected using Akaike’s criterion.Results: Forest structure and soil physical and chemical properties presented large variation among plots within the studied forest. Clay content was strongly correlated with soil moisture and the first PCA axis of soil chemical properties, and model selection indicated that clay content was a better predictor than this axis. Decomposition rates presented a large variation among tea bags (0.009 and 0.098 g g-1 day-1) and were positively related with forest structure, as characterized by higher basal area, tree density and larger trees. The stabilization factor varied between 0.211 – 0.426 and was related to forest stratification and soil clay content.Conclusions: The old-growth forest studied presented high heterogeneity in both forest structure and soil properties at small spatial scales, that influenced decomposition processes and probably contributed to small-scale variation in nutrient cycling. Decomposition rates were only influenced by forest structure, whereas the stabilization factor was influenced by both forest structure and soil properties. Heterogeneity in ecological processes can contribute to the resilience of old-growth forests, highlighting the importance of restoration strategies that consider the spatial variation of ecosystem processes.
Genome-Wide Analysis of the Response of Brucella melitensis NI to Polymyxin B
Authors: Wang Zhen , Wang Jiawei , Cheng Jie , Yang Xiaowen , Jiang Hai , Wu Qingmin 
Published: December 2020

Background:
The ability of pathogenic bacteria to survive Antimicrobial Peptides (AMPs)
in various host niches may contribute to their virulence. Polymyxin B is a cationic AMP, and polymyxin
drugs are considered to be the "last line of defense" in the clinical treatment of bacterial infections.

Objective:
The objectives of this study were to comprehensively study the response of Brucella
melitensis strain NI to polymyxin B treatment and to identify the target genes in Brucella induced by
polymyxin B stimulation.

Methods:
Following treatment with polymyxin B, differentially expressed genes in Brucella were detected
using RNA-seq and validated using qRT-PCR.

Results:
In total, 874 differentially expressed genes were identified, including 560 up-regulated and
314 down-regulated genes. Functional annotation and KEGG pathway analysis revealed that many of
these genes are involved in metabolism, two-component systems, transcriptional regulation, transport/
membrane proteins, and virulence factors. Expression of genes involved in T4SS and flagellar biosynthesis
and assembly, which are important virulence factors in Brucella, were up-regulated by polymyxin
B treatment.

Discussion:
Additionally, genes encoding the ABC transporters YejABEF and the cold-shock protein
CspA were also up-regulated. These genes confer resistance to AMPs and contribute to the virulence
of Brucella. The NIΔsufC, NIΔsufD, NIΔompW, NIΔexbB, NIΔtetR, and NIΔcspA mutants were also
more sensitive than B. melitensis NI to polymyxin B.

Conclusion:
The results of this study provide important insights into the comprehensive response of
Brucella in response to polymyxin B stimulation.
Multi-Component One-Pot Assisted Synthesis, Anti-bacterial Capabilities, and Scanning Electron Microscopy of Novel Corticosteroid Thiopyran
Authors: Sultanat  , Ansari Anam , Qamar Mohd , Shafiullah  , Tabassum Sartaj , Ansari Firoz A. 
Published: December 2020

Background:
Corticosteroids are important group of polycyclic compounds having a wide range of pharmacological and physiological properties. Thiopyran derivatives are important building blocks of many biologically active compounds.

Objective:
Keeping in mind the wide range of application of corticosteroid and thiopyran, herein we intend to develop a
simple and efficient strategy to synthesize steroidal thiopyran derivatives starting with different commercially available corticosteroid and study their biological property.

Materials and Methods:
To achieve our aim, we employed a one-pot multicomponent synthesis of steroidal thiopyran derivatives by the reaction of corticosteriods, malononitrile and carbon disulphide in presence of triethyl amine as a catalyst.

Results and Discussion :
An array of novel thiopyran compounds was obtained with the highest product yield
using Et3N. Scanning electron microscopy analysis manifested agglomeration pertaining to brick-shaped crystals
of corticosteroid thiopyran. Synthesized compounds were also found to be active as anti-bacterial agents.

Conclusion:
We describe a facile one-pot multi-component synthesis of corticosteroid thiopyran derivatives,
which are found to possess anti-bacterial activity. Excellent yields of the products, simple work-up, easily available
starting materials, and non-chromatographic purification are some of the main advantages of this protocol.
Properties of Sustainable Concrete with Mussel Shell Waste Powder
Authors: El Biriane Mohamed , Barbachi Mohamed 
Published: December 2020

Background:
The management of marine waste is a major concern in several countries. Recycling shell waste in concrete formulations may be one of the alternatives for producing sustainable materials at a lower cost.

Objective:
In this research paper, the performance of ground mussel waste for non-structural concrete formulation has been investigated.

Methods:
Two alternatives were explored in this research. The first aimed at incorporating treated Mussel Powder (MP) for partial substitution of cement (6, 12, and 24% by weight). The second aimed to investigate the feasibility of using MP as an additive with a proportion of 3, 6, 9 and 12% by weight of cement. Physico-mechanical properties of advanced composites have been studied in both fresh and hardened state through several laboratory tests.

Results:
The test results indicated that the inclusion of the MP allowed the formulation of concretes with normal density and lower air content. The mechanical behavior was characterized using new formulas adapted to the newly formulated concretes. Based on the obtained results, the treated MP could be used as a cement substitute with a proportion up to 12% or as a mineral additive with a percentage of 3% to produce a non-structural concrete that meets the normative requirements in terms of compressive and tensile strength.

Conclusion:
The recycling of mussel waste in concrete will contribute to the preservation of the environment by reducing the quantity of shellfish waste. The concept of “green” concrete can be achieved through the use of the formulated concretes in the paving works or as a blinding concrete.
GAMBARAN TINGKAT AKTIFITAS FISIK PADA MASYARAKAT KELURAHAN TOMANG JAKARTA BARAT
Authors: Lontoh Susy Olivia , Kumala Meilani , Novendy Novendy 
Published: December 2020

Lack of physical activity is a risk factor for increased incidence of coronary heart disease (CHD), type 2 diabetes mellitus (T2DM), breast cancer, colon cancer and reduced life expectancy. Regular and adequate levels of physical activity are essential to reduce the risk of non-communicable diseases. Kelurahan Tomang has an urban area and is an urban area and tends to be a sedentary life style. Data regarding the description of physical activity in the Tomang Village, West Jakarta is still limited. This study aims to determine the level of physical activity in the community of Tomang Village, West Jakarta. This research is an observational analytic study with a cross-sectional design. The study was conducted on 181 subjects and subject taking was done by consecutive sampling. Subjects in this study were aged from 20 years - 45 years with an average age of 35.1 ± 6.79 years, the majority were women as much as 55.8% and 78.5% of the subjects were married. Judging from the level of education, dominated by high school education / equivalent, the average monthly income of 42.9% of the subjects earned Rp. 3,000,001,-Rp. 4,000,000, - and most of the subjects worked as housewives and 43.1 % of subjects who did not exercise. The results of the measurement of the subject's physical activity level showed that 59.7% of subjects who had light activity and sex and type of work had an effect on the lack of physical activity Keywords: physical activity, sedentary life style ABSTRAKAktifitas fisik yang kurang menjadi faktor risiko untuk peningkatan kejadian penyakit jantung koroner (PJK), diabetes mellitus tipe 2 (T2DM), kanker payudara, kanker usus besar dan mengurangi harapan hidup. Tingkat aktifitas fisik yang teratur dan memadai sangat penting untuk mengurangi risiko penyakit tidak menular. Kelurahan Tomang berwilayah diperkotaan serta merupakan daerah urban dan cenderung sedentary life style. Data mengenai gambaran aktifitas fisik di lingkungan Kelurahan Tomang Jakarta Barat masih terbatas. Penelitian ini bertujuan untuk mengetahui gambaran tingkat aktifitas fisik pada masyarakat kelurahan Tomang Jakarta Barat. Penelitian yang dilakukan merupakan penelitian analitik observational dengan disain potong lintang. Penelitian dilakukan pada 181 subyek dan pengambilan subjek dilakukan secara consecutive sampling. Subjek dalam penelitian ini berusia mulai dari 20 tahun - 45 tahun dengan usia rata-rata adalah 35.1 ± 6,79 tahun, mayoritas adalah perempuan sebanyak 55,8 % dan 78,5 % subjek menikah. Dilihat dari jenjang pendidikan, didominasi dengan pendidikan SMA/sederajat, rata-rata penghasilan perbulan 42,9 % subjek berpenghasilan Rp.3.000.001,-Rp.4.000.000,- dan sebagian besar subjek bekerja sebagai ibu rumah tangga serta 43,1%subjek yang tidak melakukan olahraga. Hasil pengukuran tingkat aktifitas fisik subjek terlihat bahwa 59,7 % subjek yang memiliki aktifitas ringan dan jenis kelamin dan jenis pekerjaan berpengaruh terhadap kurangnya aktifitas fisik.
BUSINESS INTELLIGENCE FRAMEWORK FOR PERFORMANCE MEASUREMENT IN HIGHER EDUCATION STUDY PROGRAMS
Authors: Trisnawarman Dedi , Imam Muhammad Choirul 
Published: December 2020

Business Intelligence (BI) is an online application and realtime, needed by large and modern organizations to increase competitive advantage in the global competitive environment. Higher Education (HE) is a current organization that houses excellent resources, with the number of students reaching up to tens of thousands, thus requiring an application that can be used as a tool to achieve the organization's business goals. This study aims to build a BI model and framework aimed at developing decision-making applications for measuring the business performance of HE. The method used in this research is the BI development method which is derived from the software engineering development method and adapted to the Study Program Accreditation Instrument (IAPS) 4.0. The case study used is the Information Systems Study Program at Tarumanagara University. The BI development methods are: Business Case Assessment, Enterprise Infrastructure Evaluation, Project Planning, Project Requirements, Data Analysis, Prototyping, Meta Data Analysis, Database Design, ETL Design, Meta Data Design, ETL Development, Application Development, Data Mining, Meta Data Repository Development, Implementation, Release Evaluation. The results of this study are a development stage model and framework that can be used to build BI applications for study program performance measurement.ABSTRAK Business Intelligence (BI) adalah aplikasi daringdan terkini, dibutuhkan oleh organisasi besar dan modern untuk meningkatkan keunggulan kompetitif dalam persaingan global. Perguruan tinggi adalah organisasi saat ini yang memiliki sumber daya yang sangat baik, dengan jumlah mahasiswa mencapai puluhan ribu, sehingga membutuhkan aplikasi yang dapat digunakan sebagai alat untuk mencapai tujuan bisnis organisasi. Penelitian ini bertujuan untuk membangun model dan framework BI yang bertujuan untuk mengembangkan aplikasi pengambilan keputusan untuk mengukur kinerja bisnis PT. Metode yang digunakan dalam penelitian ini adalah metode pengembangan BI yang bersumber dari metode pengembangan rekayasa perangkat lunak dan disesuaikan dengan Instrumen Akreditasi Program Studi (IAPS) 4.0. Studi kasus yang digunakan adalah Program Studi Sistem Informasi Universitas Tarumanagara. Metode pengembangan BI adalah: Business Case Assessment, Enterprise Infrastructure Evaluation, Project Planning, Project Requirements, Data Analysis, Prototyping, Metadata Analysis, Database Design, ETL Design, Metadata Design, ETL Development, Application Development, Data Mining, Metadata Pengembangan Repositori, Implementasi, Evaluasi Rilis. Hasil dari penelitian ini berupa model tahapan pengembangan dan kerangka kerja yang dapat digunakan untuk membangun aplikasi BI untuk pengukuran kinerja program studi. Kata Kunci: Kerangka kerja Business Intelligence; Pengukuran Performa; Perguruan Tinggi
Downhole electric heating of heavy-oil wells
Authors: Karanikas John , Pastor Guillermo , Penny Scott 
Published: December 2020

Downhole electric heating has historically been unreliable or limited to short, often vertical, well sections. Technology improvements over the past several years now allow for reliable, long length, relatively high-powered, downhole electric heating suitable for extended-reach horizontal wells. The application of this downhole electric heating technology in a horizontal cold-producing heavy oil well in Alberta, Canada is presented in this paper.
The field case demonstrates the benefits and efficacy of applying downhole electric heating, especially if it is applied early in the production life of the well. Early production data showed 4X-6X higher oil rates from the heated well than from a cold-producing benchmark well in the same reservoir. In fact, after a few weeks of operation, it was no longer possible to operate the benchmark well in pure cold-production mode as it watered out, whereas the heated well has been producing for twenty (20) months without any increase in water rate. The energy ratio, defined as the heating value of the incremental produced oil to the injected heat, is over 20.0, resulting in a carbon-dioxide footprint of less than 40 kgCO2/bbl, which is lower than the greenhouse gas intensity of the average crude oil consumed in the US.
A numerical simulation model that includes reactions that account for the foamy nature of the produced oil and the downhole injection of heat, has been developed and calibrated against field data. The model can be used to prescribe the range of optimal reservoir and fluid properties to select the most promising targets (fields, wells) for downhole electric heating as a production optimization method. The same model can also be used during the execution of the project to explore optimal operating conditions and operating procedures.
Downhole electric heating in long horizontal wells is now a commercially available technology that can be reliably applied as a production optimization recovery scheme in heavy oil reservoirs. Understanding the optimum reservoir conditions where the application of downhole electric heating maximizes economic benefits will assist in identifying areas of opportunity to meaningfully increase reserves and production in heavy oil reservoirs around the world.
Media Education and the New Evangelization. Part Two: Pastoral Postulates and Educational Proposals
Authors: Chmielewski Mirosław Jan 
Published: December 2020

This article is a methodological continuation of the content presented in the first part of the author's research (“Media Education and the New Evangelization. Part One: Media Components and Challenges”, Verbum Vitae 37 [2020] 407-425) and represents an implementation of the concepts outlined there. In that previous text, the author demonstrated that pursuing a new evangelization in the Church demands the media education of evangelizers and their cooperation with the leaders of media education. This present article is aimed at formulating pastoral postulates and educational proposals based on the issues and connections that emerged. The first section outlines the postulates and educational proposals relating to those in charge of ongoing formation and who serve in the Church on the basis of the canonical authorization to teach (missio canonica). The second section contains postulates that apply to the formation of lay people and future clergy in preparing for evangelization in the Church. The third section focuses on a group of postulates concerning school religious education in light of the current Core Curriculum of the Catechesis of the Catholic Church in Poland (2018). This paper concludes with four research issues in the area of media education in the Church in the context of the current SARS-CoV-2 pandemic. The methods of the third research stage borrow from the methodological paradigm of pastoral theology, mainly in its methods of analysis and synthesis, and have been applied in the article.
Formación por competencias: Reto de la educación superior
Authors: Cejas Martínez Magda F , Rueda Manzano María José , Cayo Lema Luis Efraín , Villa Andrade Luisa Carolina 
Published: December 2020

La formación por competencias es un proceso de enseñanza y aprendizaje que está orientado a las personas con el fin de adquirir habilidades, conocimientos y actitudes para un desempeño idóneo. Este artículo tiene como objetivo analizar la formación por competencias a partir de la teoría existente, con el fin de caracterizar los factores que hacen posible garantizar a las personas un desempeño idóneo en el marco de su formación profesional. Como metodología se consideró la planteada por Samaja (2016) sustentada en el método de la comprensión (explicación) de la teoría y la episteme que gira en torno al tema objeto de estudio. El abordaje de las competencias plantea la necesidad de reconocer los requerimientos actuales de transferir desde el aprendizaje las destrezas y conocimientos las novedosas situaciones existentes en el campo profesional permitiendo así ir más allá de la educación y pasar a la profesionalización a través de un desempeño idóneo en las actividades laborales. Se concluye que los factores inherentes al proceso formativo por competencia (ser-saber y hacer) conlleva al éxito de las instituciones educativas además de establecer múltiples dimensiones en el ámbito de la formación humana destacando el desempeño idóneo en el marco del contexto laboral.