bluuebunny/crossref_metadata_2025_split huggingface dataset:
The WISSH quasars project
Authors: Travascio A. , Zappacosta L. , Cantalupo S. , Piconcelli E. , Arrigoni Battaia F. , Ginolfi M. , Bischetti M. , Vietri G. , Bongiorno A. , D’Odorico V. , Duras F. , Feruglio C. , Vignali C. , Fiore F. 
Published: February 2020

Context.In recent years, Lyαnebulae have been routinely detected around high redshift, radio-quiet quasars thanks to the advent of the highly sensitive integral field spectrographs. Constraining the physical properties of the Lyαnebulae is crucial for a full understanding of the circum-galactic medium (CGM). The CGM acts both as a repository for intergalactic and galactic baryons as well as a venue of feeding and feedback processes. The most luminous quasars are privileged test-beds to study these processes, given their large ionising fluxes and dense CGM environments in which they are expected to be embedded.Aims.We aim to characterise the rest-frame ultraviolet (UV) emission lines in the CGM around a hyper-luminous, broad emission line, radio-quiet quasar atz ∼ 3.6, which exhibits powerful outflows at both nuclear and host galaxy scales.Methods.We analyse VLT/MUSE observations of the quasar J1538+08 (Lbol = 6 × 1047erg s−1), and we performed a search for extended UV emission lines to characterise its morphology, emissivity, kinematics, and metal content.Results.We report the discovery of a very luminous (∼2 × 1044erg s−1), giant Lyαnebula and a likely associated extended (75 kpc) CIV nebula. The Lyαnebula emission exhibits moderate blueshift (∼440 km s−1) compared to the quasar systemic redshift and a large average velocity dispersion (σ¯v∼ 700 km s−1) across the nebula, while the CIV nebula shows average velocity dispersion ofσ¯v∼ 350 km s−1. The Lyαline profile exhibits a significant asymmetry towards negative velocity values at 20−30 kpc south of the quasar and is well parametrised by the following two Gaussian components: a narrow (σ ∼ 470 km s−1) systemic one plus a broad (σ ∼ 1200 km s−1), blueshifted (∼1500 km s−1) one.Conclusions.Our analysis of the MUSE observation of J1538+08 reveals metal-enriched CGM around this hyper-luminous quasar. Furthermore, our detection of blueshifted emission in the emission profile of the Lyαnebula suggests that powerful nuclear outflows can propagate through the CGM over tens of kiloparsecs.
From stellar coronae to gyrochronology: A theoretical and observational exploration
Authors: Ahuir J. , Brun A. S. , Strugarek A. 
Published: February 2020

Context.Stellar spin down is the result of a complex process involving rotation, dynamo, wind, and magnetism. Multiwavelength surveys of solar-like stars have revealed the likely existence of relationships between their rotation, X-ray luminosity, mass losses, and magnetism. They impose strong constraints on the corona and wind of cool stars.Aims.We aim to provide power-law prescriptions of the mass loss of stars, of their magnetic field, and of their base coronal density and temperature that are compatible with their observationally-constrained spin down.Methods.We link the magnetic field and the mass-loss rate from a wind torque formulation, which is in agreement with the distribution of stellar rotation periods in open clusters and the Skumanich law. Given a wind model and an expression of the X-ray luminosity from radiative losses, we constrained the coronal properties by assuming different physical scenarios linking closed loops to coronal holes.Results.We find that the magnetic field and the mass loss are involved in a one-to-one correspondence that is constrained from spin down considerations. We show that a magnetic field, depending on both the Rossby number and the stellar mass, is required to keep a consistent spin down model. The estimates of the magnetic field and the mass-loss rate obtained from our formalism are consistent with statistical studies as well as individual observations and they give new leads to constrain the magnetic field-rotation relation. The set of scaling-laws we derived can be broadly applied to cool stars from the pre-main sequence to the end of the main sequence (MS), and they allow for stellar wind modeling that is consistent with all of the observational constraints available to date.
Les résultats cosmologiques de la mission Planck
Authors: Aghanim Nabila , Dole Hervé 
Published: February 2020

Le satellite Planck a été lancé en 2009 pour mesurer avec une précision sans précédent les propriétés du rayonnement fossile – aussi appelé fond diffus cosmologique, sorte d’écho lumineux du Big Bang.
Les scientifiques de la collaboration Planck ont publié plusieurs séries de résultats, parmi lesquels les mesures les plus précises jamais obtenues de l’âge et de la composition globale de l’Univers. De plus, les données apportent un éclairage nouveau sur deux périodes particulièrement énigmatiques : l’inflation juste après le Big Bang, et la sortie des « âges sombres » quand les premières étoiles et galaxies se sont formées. L’analyse des données de Planck fournit, en outre, une mine de renseignements concernant la formation des grandes structures.
Behandlung der Mittelhand- und Phalangenfrakturen
Authors: Terzis Athanasios , Neubrech Florian , Sauerbier Michael 
Published: February 2020

ZusammenfassungMittelhand- und Phalangenfrakturen sind in der Summe die zweithäufigsten Frakturen der oberen Extremität. Die korrekte Therapie und Nachbehandlung sind essenziell für die Wiederherstellung der Funktion der verletzten Hand. Das bessere Verständnis von Anatomie und Biomechanik der Mittelhand und Phalangen sowie die Entwicklung moderner Implantate erlauben gute Ergebnisse bei der operativen Versorgung, wenn auch die konservative Therapie einen großen Stellenwert hat.
Das antimikrobielle Potenzial ätherischer Öle in der Tiermedizin – mittels Aromatogramm zur gezielten Therapie
Authors: Bismarck Doris 
Published: February 2020

ZusammenfassungÄtherische Öle sind antimikrobielle, volatile Pflanzenstoffe, die auch in der Veterinärmedizin zur Behandlung von Infektionserregern angewandt werden können. Aufgrund der unterschiedlichen Empfindlichkeit mikrobieller Erreger gegenüber ätherischen Ölen sollte vor einer Therapie ihre In-vitro-Wirksamkeit mittels Aromatogramm bestimmt werden. Beim Agardiffusionstest wird die Wirksamkeit anhand der Hemmhofgröße des mikrobiellen Wachstums eingestuft. Eine aufwendigere Methode ist die Mikrodilution, die die Möglichkeit der Bestimmung einer wirksamen Konzentration des ätherischen Öles bietet.
Prävalenz der pulmonalen Hypertonie bei Dialysepatienten mit terminaler Niereninsuffizienz
Authors: Ortwein J. , Feustel A. , Reichenberger F. 
Published: February 2020

Zusammenfassung
Hintergrund Bei Patienten mit terminaler Niereninsuffizienz ist die pulmonale Hypertonie (PH) eine häufig beschriebene Komplikation mit unterschiedlicher Ätiologie. Die Prävalenzangaben liegen zwischen 17 – 56 %. Ein Zusammenhang mit einer Volumenüberladung bei Dialysepatienten und der PH wird vermutet.
Methoden Allen Patienten des Dialysezentrums des Universitätsklinikums Gießen wurde ein nichtinvasives Screening auf PH angeboten. Bei Verdacht auf eine PH erfolgte die Korrektur der Flüssigkeitsretention anhand der Bioimpedanzspektroskopie mit dem Ziel der Normovolämie. Bei weiterem V. a. PH im erneuten Screening erfolgte eine invasive Abklärung durch Rechtsherzkatheter.
Ergebnisse 52 Patienten stimmten der Untersuchung zu. Im nichtinvasiven Screening wurde eine PH bei 12 Patienten vermutet (23 %). Nach Einstellung auf Normovolämie bestand noch bei 4 Patienten der V. a. PH (7,7 %), der sich in 2 Fällen im Rechtsherzkatheter bestätigte (3,8 %).
Diskussion Bei Patienten mit terminaler Niereninsuffizienz ist der Verdacht auf PH im nichtinvasiven Screening signifikant mit Überwässerung assoziiert. Nach Korrektur des Flüssigkeitsstatus anhand der Bioimpedanzspektroskopie wurde in unserer Erhebung eine invasiv bestätigte PH in ca. 4 % gefunden.
Steroid-responsive meningitis-arteritis in dogs in Germany: Are there epidemiological or clinical factors influencing recurrence
rate?
Authors: Hilpert Elisabeth , Tipold Andrea , Meyerhoff Nina , Schwerdt Johannes , Winkler Sandra , Jurina Konrad , Fischer Andrea , Kornberg Marion , Parzefall Birgit , Flegel Thomas 
Published: February 2020

Abstract
Objective Steroid-responsive meningitis arteritis (SRMA) is one of the most common inflammatory diseases of the central nervous system in dogs. The
present study examined breed and sex predisposition factors based on the population of dogs in Germany as well as epidemiological and clinical factors regarding
the relapse rate of SRMA.
Material and methods Data of 153 dogs with SRMA (SRMA) were analysed retrospectively in this multicentre study. It was investigated whether some dog
breeds that suffer from SRMA were disproportionately more often (n ≥ 5) represented when compared to the total population of dogs in Germany. Furthermore it was
examined which sex is affected more often. Data provided by “Verband für das deutsche Hundewesen“ (VDH) and „Tasso e. V.“ was used as reference data of the
total population. The following factors were investigated with regard to the occurrence of one or more relapses: signalment; body weight; age at first
presentation; time period between last vaccination and onset of clinical signs; clinical signs and timepoint of the first SRMA manifestation; results of
cerebrospinal fluid (CSF) analysis at first presentation (nucleated cell count and differentiation, protein concentration); immunglobulin A and C-reactive
protein (CRP) concentrations in serum and CSF; immunosuppressive medication; follow-up data including response to therapy, occurrence of relapses and mortality
including reasons, i. e. due to the disease, therapy or euthanasia.
Results The breed had a statistically significant influence on the development of SRMA (p < 0.05). Beagles and Boxers were affected more often by SRMA
than other breeds in relation to the total population in Germany. Relapses occurred in 29.4 % of the 153 dogs of this study. In contrast to the development of
SRMA, in which male dogs have a significantly increased risk of developing SRMA (p < 0.05), female dogs are more likely to relapse (p = 0.02). Patients on
prednisolone monotherapy had fewer relapses than those with prednisolone and azathioprine in combination (p < 0.05). Younger age (p = 0.071) und lower CRP
concentrations (p = 0.081) at first presentation were tentatively associated with a higher incidence of relapses.
Conclusion The determined breed and sex predispositions support the diagnosis of SRMA arteritis and confirm previous observations. This study allows a
more accurate explanation to owners about the risk of relapse.
Partizipative Gesundheitsforschung in Deutschland – quo
vadis?
Authors: von Peter Sebastian , Bär Gesine , Behrisch Birgit , Bethmann Andreas , Hartung Susanne , Kasberg Azize , Wulff Ines , Wright Michael ,   PartNet
Published: February 2020

Zusammenfassung
Ziel Ansätze der Partizipativen Gesundheitsforschung (PGF)
sind in Deutschland in der Entwicklung. In dieser Arbeit werden geeignete
Förderstrategien für die Umsetzung von Projekten der PGF in
Deutschland aufgezeigt.
Methode Es werden 9 Strategien vorgestellt und diskutiert, die auf
der Grundlage von Forschungserfahrungen von Mitgliedern der
deutschsprachigen und internationalen Netzwerke für PGF erarbeitet
wurden.
Ergebnisse Um PGF in Deutschland zu fördern, müssen
1) Mittel für Partizipation und 2) für die
Beteiligungsprozesse selbst zur Verfügung stehen; 3) in
Ausschreibungen die Aufforderung zur Partizipation grundsätzlich und
4) in speziellen Programmen auch als Förderbedingung verankert
werden; 5) Partizipation formativ evaluiert, 6) die Methodenentwicklung in
diesem Feld spezifisch gefördert und 7) die Gutachtenprozesse
angepasst werden; 8) projektübergreifende Koordinationsstellen
eingerichtet und 9) Modelle und Beispiele für Partizipation
verbreitet werden.
Schlussfolgerungen Soll nicht nur instrumentelle, symbolische oder
Schein-Beteiligung erreicht werden, ist es notwendig, die
Förderbedingungen für PGF in Deutschland anzupassen.
Large area, patterned growth of 2D MoS2 and lateral MoS2–WS2 heterostructures for nano- and opto-electronic applications
Authors: Sharma Akhil , Mahlouji Reyhaneh , Wu Longfei , Verheijen Marcel A , Vandalon Vincent , Balasubramanyam Shashank , Hofmann Jan P , (Erwin) Kessels W M M , Bol Ageeth A 
Published: February 2020

Abstract
The patterned growth of transition metal dichalcogenides (TMDs) and their lateral heterostructures is paramount for the fabrication of application-oriented electronics and optoelectronics devices. However, the large scale patterned growth of TMDs remains challenging. Here, we demonstrate the synthesis of patterned polycrystalline 2D MoS2 thin films on device ready SiO2/Si substrates, eliminating any etching and transfer steps using a combination of plasma enhanced atomic layer deposition (PEALD) and thermal sulfurization. As an inherent advantage of ALD, precise thickness control ranging from a monolayer to few-layered MoS2 has been achieved. Furthermore, uniform films with exceptional conformality over 3D structures are obtained. Finally, the approach has been leveraged to obtain in-plane lateral heterostructures of 2D MoS2 and WS2 thin films over a large area which opens up an avenue for their direct integration in future nano- and opto-electronic device applications.
Ambient-pressure high-temperature superconductivity in stoichiometric hydrogen-free covalent compound BSiC2
Authors: Chen Peng-Jen , Jeng Horng-Tay 
Published: February 2020

Abstract
High superconducting critical temperature (

T

c

) of 73.6 K at ambient pressure is predicted in BSiC2 by means of the first-principles electron–phonon calculations. Without the need for doping or pressurization, the stoichiometric BSiC2 exhibits strong electron–phonon coupling (EPC) and highest

T

c

among BCS-superconductors at ambient pressure. Also, it is hydrogen-free that makes easier the sample growth. The dramatic softening of the

E

2
g

mode is the main account for the strong EPC. In addition, we find that BC3, derived from the replacement of Si in BSiC2 by another C, is also superconducting with a high

T

c

∼ 40 K. Our work indicates that these materials form a new family of high-

T

c

BCS-superconductors at ambient pressure.
Development prospect of Glochidion sericeum as herbal medicine from Sumatra forest
Authors: Hadi EEW , Asmaliyah  , Waluyo EA 
Published: February 2020

Abstract
Disease in degenerative metabolic group requires a long-term treatment. Treatment is done with synthetic drugs which in the long run can cause side effects. Hence, people start looking for alternative treatments using ingredients from nature. Medicines from natural ingredients are also considered to have almost no harmful side effects. One type of plants that has been used by community for generations and is believed to be effective in treating ulcer disease is Glochidion sericeum. However, exploitation of the tree bark, caused the trees to languish and eventually die. So far, there has been no scientific research on the content of active ingredients and biological activity of G. sericeum, as well as the cultivation effort. This research aims to determine content of active ingredients and the efficacy of the tree leaves as herbal medicinal ingredients. The methods used in this study are: 1) Sample preparation, samples are taken from Sukaraja village, Ulu Krui sub-district, Pesisir Barat district, Lampung Province; 2) Quantitative phytochemical screening and 3) Tests of biological activities namely antidiabetic and antihyperlipidemia (anticolesterol) were carried out at the Biochemistry Laboratory, Faculty of Medicine, Lambung Mangkurat University, Banjar Baru, South Kalimantan. The test results showed that the water extract of G. sericeum leaves contained a flavonoid, steroids, tannins, alkaloids and saponins. Based on results of biological activity test, the leaves of G. sericeum have efficacy as an antidiabetic and an anticholesterol.
Characteristics of wood pellet from 5 years old JPP teak (Tectona grandis L.f.)
Authors: Gunawan I , Damayanti A , Muharyani N , Murgunadi  , Amin Y , Pari G 
Published: February 2020

Abstract
The use of renewable energy sources made from wood biomass processed in the form of wood pellets is needed to anticipate the decreasing of fossil energy (petroleum and coal). The wood biomass utilization is not only environmentally friendly and more sustainable, but also can reduce greenhouse gas emissions and environmental pollution, especially when used as power source for electricity generator. Compared to other countries, Indonesia has the potential as a major producer because it’s vast amount of forest and biodiversity that can be used as source of raw materials for wood pellets. With 2.44 million hectares forest area (including 1.22 million hectares of Teak plantation), Perum Perhutani has opportunity to develop energy wood. Large potential source is JPP (Jati Plus Perhutani) Teak wood harvested from first thinning (5 years old) and partly from second thinning (10 years old) which still inadequate for sawn timber. The aim of this study was to determine the characteristics of wood pellet from 5 years old JPP teak (Tectona grandis L.f.) as energy sources. Characteristics of wood pellet including the value of water content, calorific value, fly ash, ash content, density and sulfur content compared to the SNI 8021: 2014 quality standard. This research used CRD (Complete Random Desaign). The treatments on wood pellet making were of three different temperatures (175°C, 200°C and 225°C) applied at 2 timings (3 and 5 minutes). Samples of 5 years old JPP teak wood were obtained from KPH Cepu. The characteristics of JPP Teak wood pellets tested at the Laboratory of Timber Chemicals, Energy and NTFPs at the Forest Products Research and Development Center Bogor. Characteristics of JPP Teak wood pellets compared to national quality standards (SNI 8021: 2014) were water content (0.78 to 2.64%; max 10%), calorific value (4, 399 to 4, 585 Kcal/Kg; min 4, 000 Kcal/Kg), density (0.63 to 0.92 gr/cm3; min 0.8 gr/cm3), fly ash level (77.68 to 79.01%; max 80%), carbon content (17.16 up to 18.16%, min 14%), ash content (3.63 to 4.56%; max 1.2%) and sulfur content (0.01 to 0.02%; max 0.05%). The higher pressing temperature and time, tend to decreasing water content, sulfur content and fly ash content and increasing density and carbon content. The conclusion of this study was that 5-year-old JPP Teak wood can be used as raw material for making Wood Pellets which can meet national quality standards (SNI 8021: 2014) except for the ash content.
An investigation on structural and optical properties of nanocolumnar ZnTe thin films grown by glancing angle technique
Authors: Zarei R , Ehsani M H , Dizaji H Rezaghiolipour 
Published: February 2020

AbstractIn this paper, Zinc Telluride (ZnTe) thin films have been deposited on glass substrate by glancing angle deposition (GLAD) technique at different flux angles. The structural and optical properties of the prepared specimens have been studied with the help of x-ray diffraction (XRD), FESEM, and UV–vis analyses, respectively. According to these tests, remarkable changes in the morphology and the structure of the as-prepared samples have occurred. More significantly, using UV–vis analysis the optical properties including refractive index and band gap energy of the samples have been modified at higher deposition angles, which are promising to be applicable in optoelectronic devices.
Marker controlled superpixel nuclei segmentation and automatic counting on immunohistochemistry staining images
Authors: Shu Jie , Liu Jingxin , Zhang Yongmei , Fu Hao , Ilyas Mohammad , Faraci Giuseppe , Della Mea Vincenzo , Liu Bozhi , Qiu Guoping 
Published: February 2020

Abstract

Motivation
For the diagnosis of cancer, manually counting nuclei on massive histopathological images is tedious and the counting results might vary due to the subjective nature of the operation.

Results
This paper presents a new segmentation and counting method for nuclei, which can automatically provide nucleus counting results. This method segments nuclei with detected nuclei seed markers through a modified simple one-pass superpixel segmentation method. Rather than using a single pixel as a seed, we created a superseed for each nucleus to involve more information for improved segmentation results. Nucleus pixels are extracted by a newly proposed fusing method to reduce stain variations and preserve nucleus contour information. By evaluating segmentation results, the proposed method was compared to five existing methods on a dataset with 52 immunohistochemically (IHC) stained images. Our proposed method produced the highest mean F1-score of 0.668. By evaluating the counting results, another dataset with more than 30 000 IHC stained nuclei in 88 images were prepared. The correlation between automatically generated nucleus counting results and manual nucleus counting results was up to R2 = 0.901 (P &lt; 0.001). By evaluating segmentation results of proposed method-based tool, we tested on a 2018 Data Science Bowl (DSB) competition dataset, three users obtained DSB score of 0.331 ± 0.006.

Availability and implementation
The proposed method has been implemented as a plugin tool in ImageJ and the source code can be freely downloaded.

Supplementary information
Supplementary data are available at Bioinformatics online.
Nubeam-dedup: a fast and RAM-efficient tool to de-duplicate sequencing reads without mapping
Authors: Dai Hang , Guan Yongtao 
Published: February 2020

Abstract

Summary
We present Nubeam-dedup, a fast and RAM-efficient tool to de-duplicate sequencing reads without reference genome. Nubeam-dedup represents nucleotides by matrices, transforms reads into products of matrices, and based on which assigns a unique number to a read. Thus, duplicate reads can be efficiently removed by using a collisionless hash function. Compared with other state-of-the-art reference-free tools, Nubeam-dedup uses 50–70% of CPU time and 10–15% of RAM.

Availability and implementation
Source code in C++ and manual are available at https://github.com/daihang16/nubeamdedup and https://haplotype.org.

Supplementary information
Supplementary data are available at Bioinformatics online.
6mA-Finder: a novel online tool for predicting DNA N6-methyladenine sites in genomes
Authors: Xu Haodong , Hu Ruifeng , Jia Peilin , Zhao Zhongming 
Published: February 2020

Abstract

Motivation
DNA N6-methyladenine (6 mA) has recently been found as an essential epigenetic modification, playing its roles in a variety of cellular processes. The abnormal status of DNA 6 mA modification has been reported in cancer and other disease. The annotation of 6 mA marks in genome is the first crucial step to explore the underlying molecular mechanisms including its regulatory roles.

Results
We present a novel online DNA 6 mA site tool, 6 mA-Finder, by incorporating seven sequence-derived information and three physicochemical-based features through recursive feature elimination strategy. Our multiple cross-validations indicate the promising accuracy and robustness of our model. 6 mA-Finder outperforms its peer tools in general and species-specific 6 mA site prediction, suggesting it can provide a useful resource for further experimental investigation of DNA 6 mA modification.

Availability and implementation
https://bioinfo.uth.edu/6mA_Finder.

Supplementary information
Supplementary data are available at Bioinformatics online.