bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concerns About Information Regarding COVID-19 on the Internet: Cross-Sectional Study
Authors: Zhao Yusui , Xu Shuiyang , Wang Lei , Huang Yu , Xu Yue , Xu Yan , Lv Qiaohong , Wang Zhen , Wu Qingqing 
Published: October 2020

Background
Since the outbreak of COVID-19, the Chinese government and the Chinese Center for Disease Control and Prevention have released COVID-19–related information to the public through various channels to raise their concern level of the pandemic, increase their knowledge of disease prevention, and ensure the uptake of proper preventive practices.

Objective
Our objectives were to determine Chinese netizens’ concerns related to COVID-19 and the relationship between their concerns and information on the internet. We also aimed to elucidate the association between individuals’ levels of concern, knowledge, and behaviors related to COVID-19.

Methods
The questionnaire, which consisted of 15 closed-ended questions, was designed to investigate Chinese netizens’ knowledge about COVID-19. The self-selection online survey method of nonprobability sampling was used to recruit participants through Dingxiangyisheng WeChat (a public, medical, and health service platform in China) accounts. Standard descriptive statistics and multivariate logistic regression analyses were conducted to analyze the data.

Results
In total, 10,304 respondents were surveyed on the internet (response rate=1.75%; 10,304/590,000). Nearly all (n=9803, 95.30%) participants were concerned about “confirmed cases” of COVID-19, and 87.70% (n=9036) received information about the outbreak through social media websites. There were significant differences in participants’ concerns by sex (P=.02), age (P<.001), educational attainment (P=.001), and occupation (P<.001). All knowledge questions and preventive practices were associated with concerns about COVID-19. The results of the multivariate logistic regression indicated that participants’ sex, educational attainment, occupation and employment status, knowledge acquisition, and concern level were significantly associated with the practice of proper preventive behaviors.

Conclusions
This study elucidated Chinese netizens’ concerns, information sources, and preventive behaviors related to the COVID-19 pandemic. Sex, educational attainment, occupation and employment status, knowledge acquisition, and level of concern were key factors associated with proper preventive behaviors. This offers a theoretical basis for the government to provide targeted disease prevention and control information to the public.
Using an Ontology to Facilitate More Accurate Coding of Social Prescriptions Addressing Social Determinants of Health: Feasibility Study
Authors: Jani Anant , Liyanage Harshana , Okusi Cecilia , Sherlock Julian , Hoang Uy , Ferreira Filipa , Yonova Ivelina , de Lusignan Simon 
Published: October 2020

Background
National Health Service (NHS) England supports social prescribing in order to address social determinants of health, which account for approximately 80% of all health outcomes. Nevertheless, data on ongoing social prescribing activities are lacking. Although NHS England has attempted to overcome this problem by recommending 3 standardized primary care codes, these codes do not capture the social prescribing activity to a level of granularity that would allow for fair attribution of outcomes to social prescribing.

Objective
In this study, we explored whether an alternative approach to coding social prescribing activity, specifically through a social prescribing ontology, can be used to capture the social prescriptions used in primary care in greater detail.

Methods
The social prescribing ontology, implemented according to the Web Ontology Language, was designed to cover several key concepts encompassing social determinants of health. Readv2 and Clinical Terms Version 3 codes were identified using the NHS Terms Browser. The Royal College of General Practitioners Research Surveillance Centre, a sentinel network of over 1000 primary care practices across England covering a population of more than 4,000,000 registered patients, was used for data analyses for a defined period (ie, January 2011 to December 2019).

Results
In all, 668 codes capturing social prescriptions addressing different social determinants of health were identified for the social prescribing ontology. For the study period, social prescribing ontology codes were used 5,504,037 times by primary care practices of the Royal College of General Practitioners Research Surveillance Centre as compared to 29,606 instances of use of social prescribing codes, including NHS England’s recommended codes.

Conclusions
A social prescribing ontology provides a powerful alternative to the codes currently recommended by NHS England to capture detailed social prescribing activity in England. The more detailed information thus obtained will allow for explorations about whether outputs or outcomes of care delivery can be attributed to social prescriptions, which is essential for demonstrating the overall value that social prescribing can deliver to the NHS and health care systems.
COMPARISON OF MALASSEZIA SPP. PROPORTIONS IN INFLAMMATORY AND NON-INFLAMMATORY FACIAL ACNE VULGARIS LESIONS
Authors: SUTARJO AGASSI SUSENO , SITOHANG IRMA BERNADETTE S. , WAHID MARDIASTUTI H. , WIDATY SANDRA 
Published: October 2020

Objective: The skin microbiome plays a role in the pathogenesis of acne vulgaris (AV). Among other species, Malassezia spp. can be found in the pilosebaceous follicle. However, its role on the pathogenesis of AV has not yet been described. The objective of this study was to identify the presence and the distribution of Malassezia spp. in facial AV lesions and also to compare the distribution of Malassezia spp. between inflammatory and non-inflammatory lesions.
Methods: One hundred and twenty subjects were allocated into two groups: inflammatory lesions and non-inflammatory lesions. Samples were taken from hair follicles and examined by microscopy using 20% potassium hydroxide and Parker ink and cultured for species identification.
Results: There was no difference in the spore load between the two groups (p=0.142). Malassezia spp. were isolated from 64.2% of subjects and consisted of M. dermatis (43%), M. sympodialis (18%), M. slooffiae (16%), M. japonica (5%), M. furfur (5%), M. pachydermatis (3%), and M. restricta (1%). There was a higher Malassezia spp. proportion in non-inflammatory lesions (p=0.019). The predominant species in inflammatory AV lesions was M. dermatis (45,8%), followed by M. sympodialis (17.1%), and M. slooffiae (11.4%).
Conclusion: Malassezia spp. were found in facial acne lesions. M. dermatis was the predominant species found in facial AV, followed by M. sympodialis, and M. slooffiae. A higher proportion of Malassezia spp. was found in non-inflammatory lesions.
THE EXPRESSION OF NESTIN IN THE INDUCED DIFFERENTIATION INTO NEURONS OF RAT BONE MARROW MESENCHYMAL STEM CELLS BY NEUROTROPHIN-3 (NT-3)
Authors: NOVIANTARI ARIYANI , ANTARIANTO RADIANA DHEWAYANI , RIF’ATI LUTFAH , RINENDYAPUTRI RATIH , ZAINURI MASAGUS , DANY FRANS 
Published: October 2020

Objective: The aim of this study was to examine the role of NT-3 as a single neurotrophic factor in the expression of nestin in the neural differentiation of MSCs.
Methods: MSCs were isolated from rat bone marrow and induced with NT-3 at concentrations of 20, 25, and 30 ng/ml for 7 and 14 d (the control was no NT-3). Nestin underwent immunocytochemical analysis on days 7 and 14. Five high-power random fields were documented.
Results: A post-hoc analysis using LSD after one-way ANOVA test yielded a statistically significant difference in the percentage of nestin-positive cells in MSCs with NT-3 at concentrations of 20, 25, and 30 ng/ml for 7 d compared to the control group (p<0.05). The percentages of nestin-positive cells at concentrations of 20, 25, and 30 ng/ml, and in the control data on day 7 were 14.55±1.26%, 16.20±1.07%, 13.78±1.19%, and 9.81±0.79%, respectively. NT-3 at 25 ng/ml induced the highest MSCs neural differentiation on day 7 and remained constant until day 14.
Conclusion: NT-3 plays a role in the early stage of differentiating MSCs from rat bone marrow into neurons, with the optimal concentration being 25 ng/ml.
THE COMPARISON OF CONFIGURATION, DEGREE AND SITES OF OBSTRUCTION IN PATIENTS WITH SLEEP DISORDERED BREATHING: EXAMINATION USING DRUG-INDUCED SLEEP ENDOSCOPY, MUELLER MANEUVER AND POLYSOMNOGRAPHY
Authors: RIZKI NIKEN AGENG , TAMIN SUSYANA , FARDIZZA FAUZIAH , WARDANI RETNO S. , MARSABAN ARIEF , BARDOSONO SAPTAWATI , RACHMAWATI ELVIE ZULKA KAUTZIA 
Published: October 2020

Objective: The purpose of this study is to evaluate the location, configuration, and degree of differences in upper airway obstruction between the Mueller Maneuver (MM) and Drug-induced sleep endoscopy (DISE), thus acquiring a better diagnostic value for SDB patients.
Methods: A cross-sectional and analytical descriptive study using retrospective secondary data to evaluate the location, configuration and degree of upper airway obstruction in SDB subjects using the Mueller Maneuver and DISE. Polysomnography (PSG) type 2 was used to determine the SDB degree.
Results: Subjects with SDB non-Obstructive sleep apnea (OSA) and OSA show a multilevel obstruction with a different location and configuration due to the various risk factors, such as nasal congestion, laryngopharyngeal reflux, obesity and menopause.
Conclusion: Statistical differences in upper airway obstruction configuration between MM and DISE were found in the level of the velum (p=0,036), oropharynx (p<0,001) and epiglottis (p=0,036) and were also found in the obstruction degree of the velum, oropharynx, tongue base and epiglottis with p=0,002; p<0,001; p<0,001 and p<0,001. No statistical difference was found on the lowest oxygen saturation between PSG and DISE (p=0,055).
THE VIABILITY TEST OF SAPPAN WOOD (CAESALPINIA SAPPAN L.) ETHANOL EXTRACT IN THE H9C2 CELL LINE
Authors: SULISTIYORINI IFA , SAFITRI RATU , LESMANA RONNY , SYAMSUNARNO MAS RIZKY A. A. 
Published: October 2020

Objective: In this study, the embryonic rat cardiomyocyte cell line H9C2 was used to investigate the cardiotoxicity effect of sappan wood ethanol extract (SWEE).
Methods: Sappan wood was extracted in 96% ethanol and divided into dose concentrations of 2.5, 5, 10, 50, 100, and 150 μg/ml, with deferiprone used as a control. Cell viability was assessed using the PrestoBlue Cell Viability Reagent, according to manufacturer protocols.
Results: Microscopic examination showed that the cell viability of H9C2 was preserved by SWEE treatments at a dose of 10 μg/ml and suggested dose concentrations of 50 μg/ml of SWEE. The percentage of viable cells was greater than 95% with a dose concentration of 10 μg/ml of SWEE, but it was significantly reduced with a dose concentration of 50 μg/ml of SWEE (p<0.05).
Conclusion: The optimal dose concentration of SWEE to reach 95% cell viability was 10 μg/ml.
INCUBATION OF PLATELET-RICH FIBRIN MATRIX WITH MESENCHYMAL STEM CELLS IMPROVES MATRIX STIFFNESS
Authors: REKSODIPUTRO MIRTA H. , PRATAMA GITA , WIWEKO BUDI , KUSUMAWARDHANI EVANTHI , RAHAYU DENISWARI , NAULI RAISA , MARTIN VALENCIA JANE , SANDORA NORMALINA 
Published: October 2020

Objective: The platelet-rich fibrin matrix (PRFM) is condensed platelet-rich plasma (PRP) and should possess a comparable biomechanical property to the transplanted sites, for them to be physiologically functional. The aim of this study was to investigate the effect of human bone marrow mesenchymal stem cells (hBM-MSC) or human umbilical cord mesenchymal stem cells (hUC-MSC) on the biomechanical properties of PRFM.
Methods: PRFM was prepared by the gelation of PRP using 25 mmol CaCl2. The resulting coin-shaped PRFM pellets, 5 cm in diameter and 300 μm thick, were directly seeded with hUC-MSC or hBM-MSC at 2,000 cells cm-2, followed by 24 h incubation at 37 °C in 5% (v/v) CO2 in air. The samples were then observed by scanning electron microscopy to determine the morphology of the matrix surface. The PRFM biomechanical properties were determined at a 10 mm. min-1failure rate using an MCT 2150 universal testing machine (AandD Co. LTD).
Results: SEM imaging of the surface of the PRFM seeded with hBM-MSC and hUC-MSC showed a cloudy layer that thickened over time. The elastin slope of the PRFM was significantly improved after seeding with hBM-MSC and hUC-MSC when compared with unseeded PRFM (p<0.002, R2=0.983). Both cell types elicited similar biomechanical effects (p=0.99).
Conclusion: PRFM seeded with hBM-MSC or hUC-MSC showed significantly increased elasticity.
Safety of pertussis vaccines for adolescents
Authors: Kostinov M. P. , Prutskova E. V. , Cherdantsev A. P. , Feiskhanova G. R. , Kostinov A. M. , Vlasenko A. E. , Polishchuk V. B. 
Published: October 2020

Aim: to investigate the safety of acellular pertussis vaccines for adolescents.Materials and methods. The clinical tolerability of revaccination against pertussis (cell-free component), diphtheria and tetanus was analyzed in 107 children aged 13,5–14 years. Group 1 consisted of children revaccinated with DTacP-IPV combined vaccine (Tetraxim), group 2 – vaccinated with Td and group 3 – children who received Tdap vaccine (Adacel).Results. Statistically significant differences in the frequency of local reactions between the group that received Tdap and the other two (DTacP-IPV and Td) were detected (p = 0.001and p = 0.04, respectively). Analysis of the structure of local reactions revealed a difference only in the occurrence of the hyperemia at the site of injection, with the most frequent registration in the groups of children vaccinated with DTacPIPV (29,4%) and Td (14,7%), whereas in patients vaccinated with Tdap – only in 5,9% (χ2 = 6,8 p = 0,03). Systemic reactions occurred with the same frequency in all studied groups and did not require medical correction, as well as local reactions. Thus, revaccination against pertussis, diphtheria and tetanus of adolescents using Tdap, containing the acellular pertussis component, does not exceed the frequency of systemic reactions and the number of local reactions is significantly lower in comparison with the vaccine with a reduced content of diphtheria and tetanus toxoids (Td) that is used in practice for a long time.
Epidemiological and clinical features of acute respiratory infections occurring in St. Petersburg during the 2017–2018 and 2018–2019 epidemic seasons
Authors: Guzhov D. A. , Elpaeva E. A. , Egorova M. A. , Eder V. A. , Baranovskaya I. L. , Klotchenko S. A. , Tokin I. I. , Vasin A. V. 
Published: October 2020

Objective: to analyze the epidemiological and clinical features of acute respiratory infections occurring during the St. Petersburg 2017–2018 and 2018–2019 epidemic seasons.Materials and methods: the study included 457 patients, treated in St. Petersburg clinics from 2017–2019, displaying symptoms of acute respiratory infection (ARI), including evaluation of their clinical histories. Pathogen types were determined by polymerase chain reaction (PCR). Data analysis was carried out using mathematical statistics methods using the Statistica 10 software package (StatSoft Inc.).Results: in this study, we examined the epidemiological and clinical features of acute respiratory infections in St. Petersburg occurring during two epidemic seasons, 2017–2018 and 2018–2019. The 2017–2018 season was characterized by a prevalence of infections caused by influenza B viruses and influenza A subtype H3N2 viruses. In the 2018–2019 season, there was a greater number of acute respiratory viral infections (ARVIs) and infections caused by influenza A subtype H1N1pdm; influenza B virus was detected only in isolated cases. In the 2017–2018 sore throats and muscle aches were a characteristic symptom of influenza A H1N1pdm infections, of bacterial infections – only sore throats. It was shown that throat pain and vasodilation of the scleral and soft palate vessels were significantly more frequent in the 2017–2018 season, compared to the 2018–2019 season. Cough and redness of the posterior pharyngeal wall were hallmark signs of ARVIs in the 2018–2019 season.Conclusion: according to the data, each epidemic season is characterized not only by its own type-specific acute respiratory infection frequencies, but also by different clinical manifestation frequencies. For global monitoring, treatment effectiveness evaluation, and refined study of acute respiratory infection clinical features, it is advisable to use approaches which incorporate accurate, specific, and rapid molecular biological methods capable of identifying a broad range of pathogens.
Laboratory attitudes and practices in the conservation of biological tissues for research purposes in Cote d'Ivoire
Authors: Kintossou Ambroise Kouamé , N'Dri Mathias Kouamé , Money Marcelle , Diané Maxime Kouao , Cissé Souleymane , Soumahoro Man Koumba , Coulibaly Amadou Founzégué , Djaman Joseph Allico , Dosso Mireille 
Published: October 2020

Background : Since 2009, Côte d'Ivoire has had a biobank, which now houses the ECOWAS regional biobank. This biobank intends to set up a biological tissue bank for research. In Côte d'Ivoire, several public and private structures handle biological tissues. However, we do not know which ones are involved in the conservation of biological tissues and their related procedures. To ensure optimal conservation of biological tissues at the biobank of Côte d'Ivoire, it is necessary to conduct a study on the state of the art of tissue preservation in Côte d'Ivoire. The objective of our work is to know the attitudes and practices of biological tissue preservation in Côte d'Ivoire.Methods : This is a descriptive study carried out in biological analysis laboratories in the south of the Ivory Coast.Results : A total of 66 laboratories agreed to answer the questionnaire that was proposed to them. Among them, only 21.21% kept biological tissues, of which 42.86% were human tissues, 35.71% animal tissues and 21.43% plant tissues. Human tissuesz were stored in formalin at room temperature for a period ranging from 2 weeks to 6 months. Animal biopsies and surgical specimens were stored in formalin and at -80°C for an indefinite period of time. Plant tissues were stored at room temperature and +4°C for an indefinite period of time.Conclusion : The conservation quality of biological tissues still needs to be improved.
I Implementasi Sistem Hermitian Generalized LED Index Modulation (H-GLIM-OFDM) pada Board FPGA Xilinx Arty Artix-7
Authors: Yuniati Yetti 
Published: October 2020

Abstrak— Komunikasi nirkabel menjadi jenis komunikasi yang digunakan secara luas, spektrum radio yang umumnya digunakan dalam komunikasi nirkabel menjadi tidak cukup untuk memenuhi tuntutan yang tinggi. Visible Light Communication (VLC) menjadi solusi untuk mengatasi kapasitas bandwidth yang kurang memadai ini. Orthogonal Frequency Division Multiplexing (OFDM) menjadi teknik yang dikembangkan untuk sistem komunikasi cahaya tampak karena pada teknik OFDM frekuensi yang digunakan saling orthogonal dan memungkinkan overlap antar frekuensi tanpa menimbulkan interferensi satu sama lain sehingga menghasilkan kecepatan transfer data yang tinggi. Jurnal ini membahas tentang Implementasi Sistem Hermitian Generalized LED Index Modulation (H-GLIM-OFDM). Skema dari H-GLIM-OFDM ini dirancang dalam System Generator pada bahasa pemograman Matlab. Desain di implementasikan dalam FPGA dan diterapkan dengan spesifikasi Arty Board Xilinx Artix-7. Field Programmable Gate Array (FPGA) merupakan perangkat semikonduktor yang dapat diprogram secara fleksibel dan dapat melakukan kinerja yang tinggi untuk implementasi VLC. Hasil yang didapat pada simulasi ini yaitu menggunakan pemanfaatan sumber daya desain 5% BRAM, 11% dari DSP, 8% dari LUT, 18% dari IO, dan 3% BUFG.

Kata Kunci : H-GLIM-OFDM, FPGA Arty Artix-7, Visible Light Communication, Vivado, System Generator
Analisis Situasi Penggunaan Google Classroom pada Pembelajaran Daring Fisika
Authors: Agung Mahardini Maya Mahitsa 
Published: October 2020

Analisis Situasi pembelajaran daring Fisika dengan menggunakan Google Classroom.. Desain penelitian yang digunakan adalah kualitatif deskriptif. Responden dalam penelitian ini yaitu peserta didik dan Guru Mata Pelajaran Fisika di SMAN 1 Pedes. Fokus penelitian ini yaitu situasi pembelajaran daring Fisika dengan menggunakan Google Classroom. Teknik pengumpulan data meliputi wawancara, dan observasi. Teknik analisis yaitu reduksi data, display data dan penarikan kesimpulan. Hasil penelitian menunjukkan perubahan metode pembelajaran fisika konvensional berupa tatap muka antara guru dengan peserta didik di kelas yang dilakukan dengan pemaparan materi, diskusi, tanya jawab ataupun praktikum menjadi metode daring menggunakan Google Classroom mempunyai kelebihan dan kekurangan yang dirasakan oleh guru maupun peserta didik. Kelebihannya diantaranya guru dapat menggunakan berbagai media untuk proses pembelajaran, baik yang terdapat dalam Google Classroom atau media lain yang bisa ditautkan pada classroom tersebut. Sedangkan kekurangannya yaitu permasalahan jaringan maupun keterbatasan kuota yang dimiliki peserta didik bisa menjadi penghambat dalam proses pembelajaran, pun begitu pula dengan rendahnya tingkat keaktifan peserta didik dalam proses pembelajaran. Selain itu, guru merasakan adanya kesulitan untuk menjelaskan materi yang terdapat persamaan-persamaan fisika, peserta didik pun mengalami kesulitan dalam memahami materi tersebut yang berdampak pada rendahnya kemampuan peserta didik menyelesaikan soal hitungan.Dalam menghadapi kendala tersebut, sudah dicoba dilakukan pemberian materi dibatasi pada kompetensi-kompetensi dasar yang esensial dan dibuatkan suatu media pembelajaran dengan bahasa sederhana yang lebih mudah dipahami oleh peserta didik.Kata Kunci : pembelajaran daring, pembelajaran fisika, Google Classroom, kualitatif deskriptif
Disputar la autoridad
Authors: Caviglia Mariana 
Published: October 2020

La autora recupera el debate sobre la autoridad etnográfica que se produjo en la antropología a partir de las corrientes posmodernas que redujeron la cultura,la etnografía y la reflexividad a la textualidad, y aborda los principales cuestionamientos a los supuestos en los que se funda esta concepción y la problematización sobre las formas de construcción de la autoridad, desde la asunción de la etnografía como perspectiva y método de conocimiento.
Redesain Dan Analisa Kelayakan PLTMH 25 KW Desa Susuan Karangasem Bali
Authors: Budiantara Dewa Nyoman Tri , Kumara I Nyoman Satya , Giriantari I.A.D 
Published: October 2020

Intisari— Kebutuhan akan energi listrik Indonesia selalu meningkat dari tahun ke tahun. Di Indonesia penggunaan pembangkit listrik tenaga fosil masih banyak digunakan. Energi air sendiri merupakan alternatif untuk menggantikan bahan bakar dari fosil secara umum, salah satunya Pembangkit Listrik Tenaga Mikro Hidro. Penilitian ini dibuat untuk mengindentifikasi PLTMH di Desa Sususan Karangasem dapat di revitalisasi (dibangun kembali) melalui pengukuran dan perhitungan potensi sumber daya air dengan metode flow duration curve dengan probabilitas terlampaui 80%. Untuk menganalisis kelayakan PLTMH dilakukan analisis finansial yakni Net Present Value (NPV), Internal Rate Ratio (IRR), Payback Period (PP) dan Benefit Cost Ratio (BCR). Hasil dari analisis didapatkan potensi dari PLTMH Karangasem saat ini yakni 25,18 kWh dengan pembangkitan listrik per tahun sebesar 220,577 kWh/ tahun dan BPP listrik = Rp. 774.- per kWh. Dari hasil analisis, PLTMH Desa Susuan Karangasem dapat dikatakan layak untuk dilakukan revitalisasi.
Kata Kunci: Pembangkit Listrik Tenaga Mikro Hidro (PLTMH), Analisis Hidrologi, Analisis Ekonomi Energi, Revitalisasi