bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of quercetin on tight junctional proteins and BDNF signaling molecules in hippocampus of PCBs-exposed rats
Authors: Selvakumar Kandaswamy , Bavithra Senthamilselvan , Krishnamoorthy Gunasekaran , Arunakaran Jagadeesan 
Published: October 2019

Abstract
Polychlorinated biphenyls (PCBs) consist of a range of toxic substances which are directly proportional to carcinogenesis and tumor-promoting factors as well as having neurotoxic properties. Reactive oxygen species, which are produced from PCBs, alter blood–brain barrier (BBB) integrity, which is paralleled by cytoskeletal rearrangements and redistribution and disappearance of tight junction proteins (TJPs) like claudin-5 and occludin. Brain-derived neurotrophic factor (BDNF), plays an important role in the maintenance, survival of neurons and synaptic plasticity. It is predominant in the hippocampal areas vital to learning, memory and higher thinking. Quercetin, a flavonoid, had drawn attention to its neurodefensive property. The study is to assess the role of quercetin on serum PCB, estradiol and testosterone levels and mRNA expressions of estrogen receptor α and β, TJPs and BDNF signaling molecules on the hippocampus of PCBs-exposed rats. Rats were divided into 4 groups of 6 each. Group I rats were intraperitoneally (i.p.) administered corn oil (vehicle). Group II received quercetin 50 mg/kg/bwt (gavage). Group III received PCBs (Aroclor 1254) at 2 mg/kg bwt (i.p). Group IV received quercetin 50 mg/kg bwt (gavage) simultaneously with PCBs 2 mg/kg bwt (i.p.). The treatment was given daily for 30 days. The rats were euthanized 24 h after the experimental period. Blood was collected for quantification of serum PCBs estradiol and testosterone. The hippocampus was dissected and processed for PCR and Western blot; serum PCB was observed in PCB treated animals, simultaneously quercetin treated animals showed PCB metabolites. Serum testosterone and estradiol were decreased after PCB exposure. Quercetin supplementation brought back normal levels. mRNA expressions of estrogen α and β were decreased in the hippocampus of PCB treated rats. TJPS and BDNF signalling molecules were decreased in hippocampus of PCB treated rats. Quercetin supplementation retrieved all the parameters. Quercetin alone treated animals showed no alteration. Thus in PCB caused neurotoxicity, quercetin protects and prevents neuronal damage in the hippocampus.
Measurement of melamine migration from melamine-ware products by designed HPLC method and the effect of food-type on the level of migration
Authors: Haghi Ehsan , Alimohammadi Mahmood , Shakoori Attaollah , Razeghi Fariba , Sadighara Parisa 
Published: October 2019

Abstract
Melamine-ware is widely used around the world. There is a public health concern as regards the safety of melamine when exposed to food. This study was carried out to measure the level of melamine migration in melamine-ware products by HPLC method and the effect of food-type on the level of melamine migration. In food control laboratories in Iran, there is no common method to measure and monitor melamine migration, hence a method using HPLC technique was adopted and validated to solve this problem. The validation results showed the reliability with 94.9% accuracy and 95.3% precision. Furthermore, the limit of detection (LOD) and quantification (LOQ) were 0.145 and 0.435 µg/ml, which for a new method were within acceptable ranges. Melamine migrations from 4 most available melamine wares were measured. Distilled water, 3% acetic acid and 15% ethanol were used as food simulant at 30 °C for 90 min. Although melamine migration occurred in all samples and acidic conditions had a significant effect, the values were not higher than the European standard (30 µg/ml). The study revealed that the HPLC method was valid and could be applied and developed to measure melamine migration. However, precautions should be considered while choosing melamine-ware utensil as long-term exposure to this substance has a negative effect on health, especially on the kidneys.
Alteration in MDA, GSH level and hematological changes due to thiamine deficiency in Mus musculus
Authors: Sharma Anupama , Bist Renu 
Published: October 2019

Abstract
It is known that thiamine deficiency may lead to Alzheimer’s diseases in humans. The present study has thus been conducted to understand the role of thiamine deficiency with respect to alteration in the peripheral blood of Swiss albino mice. For this purpose, adult Swiss albino mice (6–8 week old) were divided into three groups. The first group was control; the second (group II) and the third group (group III) were made thiamine deficient for 08 and 10 days respectively. Thiamine deficiency was induced in mice by injecting pyrithiamine (5 µg/10 g bwt) and feeding a thiamine deficient diet. The erythrocytes, leukocytes count, hemoglobin, hematocrit value, mass cell volume, mean corpuscular hemoglobin in blood of mice were determined by hematoanalyzer. Malondialdehyde (MDA) and reduced glutathione (GSH) level was also determined in serum of treated and non-treated groups. A significant reduction in leukocyte and erythrocyte count was observed in both the thiamine deficient groups as compared to control. Levels of hemoglobin and hematocrit value were also declined in the thiamine deficient groups. Enhancement in mass cell volume (MCV) level and decline in mean corpuscular hemoglobin (MCH) levels were observed in both thiamine deficient groups with respect to control. Inter-group comparison of all parameters also showed a significant value at p<0.01. In comparison with the control group, elevation in MDA and decline in GSH level was observed in both thiamine deficient groups which were statistically significant. These data indicate that thiamine deficiency leads to significant alterations in the hematological parameters as well as in MDA and GSH level.
Lyapunov Function based Criteria for Ship Rolling in Random Beam Seas
Authors: Üçer Erdem 
Published: October 2019

Abstract
The aim of this study is to present a Lyapunov function which can be used to derive an intact stability criterion for a ship in random beam seas. First, the mathematical model of the rolling motion of ships in random beam seas is introduced. The random wave excitation is described by a spectrum which is depended on the wave energy spectrum and the amplitude of the moment of roll. This spectrum is generated by a second order linear filter. Second, the methodology of creating a Lyapunov function is explained briefly. Then, there is outlined the way by which Lyapunov function can be used as the intact stability criterion for a ship. The proposed criterion is derived by considering the weather criteria for German naval vessels. Finally, the coherence of the boundary of safe basin obtained by Lyapunov function with the numerical results obtained by Euler-Maruyama Method is presented. From the results it can be deduced that the Lyapunov function can be used to define an intact stability criterion.
Analysis and Experiments of Embedded Gripping Mechanism Used in Large-scale Tools Holding Up Pile Foundation in Ocean
Authors: Wang Zhuo , Zhang Bo , Wang Tao 
Published: October 2019

Abstract
With the rapid development of the marine economy and continuous improvement of the industry, the scale of the offshore engineering is increasing. This raises interest in studying, theoretically and experimentally, gripping and bearing mechanisms for large-scale holding and lifting tools used in foundation pile installations. In this paper, the embedded gripping mechanism is studied based on the theory of elastic-plastic mechanics. The embedded and bearing performance of the tooth is simulated and the influence factors are studied. In addition, the device used in the simplified embedded experiment on the tooth of the embedded block is designed. The relationship between embedded depth, load, and tooth profile angle is identified and validated. Meanwhile, the embedded performance of linear and ring type teeth is compared experimentally in order to select the suitable type of tooth for various situations. This comparison makes the basis for designing an upending gripper for the marine pile foundation, which can realize the operation of holding the pile to prevent its falling.
A Concept Design of Diesel – Hydraulic Propulsion System for Passenger Ship Intended for Inland Shallow Water Navigation
Authors: Dymarski Czesław 
Published: October 2019

Abstract
This paper presents an analysis of environmental and technical conditions necessary for working out a possibly most favourable propulsion system for a two – segment passenger ship intended for navigation between Berlin and Kaliningrad. There are presented various types of propulsion systems for small ships as well as analyzed their possible applications and consequences. In this work there were taken into account system’s reliability, efficiency, dimensions, mass and costs of manufacturing, assembling and possible replacing the system components as well as an impact on maneuverability and natural environment. With taking into account the above mentioned criteria it was finally found that the diesel-hydraulic system fitted with two azimuthal ducted solid propellers is the most favourable. There are also presented a schematic propulsion and control diagram, three-dimensional arrangement drawing of system components as well as assembly drawing of the designed azimuthal propulsion system.
Energy Loss Coefficients ki
in a Displacement Pump and Hydraulic Motor used in Hydrostatic Drives
Authors: Maczyszyn Agnieszka 
Published: October 2019

Abstract
The article aims at defining and analysing the energy loss coefficients in design solutions of rotating displacement machines, with a piston machine as an example. The energy losses observed in these machines include mechanical loss, volumetric loss, and pressure loss. The scale and relations between these losses in different machines depend on machine design and manufacturing quality, and on operating parameters. The operating parameters, in turn, which affect directly or indirectly the above losses depend on whether the machine works in pump or hydraulic motor regime. The article is also a contribution to the development of a library of ki coefficients which define the losses in displacement machines, as the knowledge about these coefficients makes it possible to assess fast and easily the energy efficiency of a machine or drive system at each point of its working area.
Dynamic Characteristic Study of Riser with Complex Pre-stress Distribution
Authors: Chen Luyun , Yi Hong 
Published: October 2019

Abstract
In this study, the dynamic characteristic problem of riser structure with complex pre-stress distribution is investigated. At first, the differential equation of the riser structure with complex pre-stress distribution is derived. The analytical expression of the free vibration of a riser structure with complex pre-stress distribution is discussed by using the orthogonal property of the trigonometric series. A top-tensioned riser (TTR) for example, the influences of the amplitude and direction of complex pre-stress on natural frequency and mode shape characteristics are compared. This study provides a new method for addressing the riser structure response problem with complex loading.
The Energy Efficiency Gap in Turkish Maritime Transportation
Authors: Konur Olgun , Bayraktar Murat , Pamik Murat , Kuleyin Barış , Nuran Mustafa 
Published: October 2019

Abstract
The Turkish Merchant Shipping Industry has recently witnessed an increasing awareness of the importance to minimize environmental pollution and fuel oil consumption. Together with certain non-governmental organizations and media concerns about environmental protection, the International Maritime Organization (IMO) has been strict on controlling undesirable effects on the environment and, consequently, forcing shipping companies to minimize their emissions. Besides, today’s highly advanced technology companies over the world have developed various innovative systems that can be utilized to minimize carbon emission, thus giving assurance to relevant investors that their investments are most likely to turn out well with a considerable financial gain in the short or long term. Despite all such favorable developments, in a general look, shipping companies seem reluctant in making use of technologies providing efficiency in energy consumption. This reluctance has eventually brought about the term “Energy Efficiency Gap”. This research conducts a questionnaire, created by Acciaro et al. [1], among the shipping companies in Turkey. 20 respondent companies, who represent 26 percent of the Turkish owned merchant marine fleet of over 1000 gross tonnage in terms of deadweight cargo capacity, participated in the research. The Pearson correlation analysis was used, and interpretations were made according to the obtained statistical values. The aim of the research was to identify reasons and points restraining the use of new technologies regarding energy efficiency, as well as to develop proposals for the innovators in this field about how to overcome this handicap concerning technical and managerial aspects of gaining energy efficiency.
Ship Maneuvering Prediction Using Grey Box Framework via Adaptive RM-SVM with Minor Rudder
Authors: Mei Bin , Sun Licheng , Shi Guoyou , Liu Xiaodong 
Published: October 2019

Abstract
A grey box framework is applied to model ship maneuvering by using a reference model (RM) and a support vector machine (SVM) (RM-SVM). First, the nonlinear characteristics of the target ship are determined using the RM and the similarity rule. Then, the linear SVM adaptively fits the errors between acceleration variables of RM and target ship. Finally, the accelerations of the target ship are predicted using RM and linear SVM. The parameters of the RM are known and conveniently acquired, thus avoiding the modeling process. The SVM has the advantages of fast training, quick simulation, and no overfitting. Testing and validation are conducted using the ship model test data. The test case reveals the practicability of the RF-SVM based modeling method, while the validation cases confirm the generalization ability of the grey box framework.
Model Predictive Super-Twisting Sliding Mode Control for an Autonomous Surface Vehicle
Authors: Esfahani Hossein Nejatbakhsh , Szlapczynski Rafal 
Published: October 2019

Abstract
This paper presents a new robust Model Predictive Control (MPC) algorithm for trajectory tracking of an Autonomous Surface Vehicle (ASV) in presence of the time-varying external disturbances including winds, waves and ocean currents as well as dynamical uncertainties. For fulfilling the robustness property, a sliding mode control-based procedure for designing of MPC and a super-twisting term are adopted. The MPC algorithm has been known as an effective approach for the implementation simplicity and its fast dynamic response. The proposed hybrid controller has been implemented in MATLAB / Simulink environment. The results for the combined Model Predictive Super-Twisting Sliding Mode Control (MP-STSMC) algorithm have shown that it significantly outperforms conventional MPC algorithm in terms of the transient response, robustness and steady state response and presents an effective chattering attenuation in comparison with the Super-Twisting Sliding Mode Control (STSMC) algorithm.
Application of the Optimization Methods to the Search of Marine Propulsion Shafting Global Equilibrium in Running Condition
Authors: Ursolov Aleksandr , Batrak Yuriy , Tarelko Wieslaw 
Published: October 2019

Abstract
Full-film hydrodynamic lubrication of marine propulsion shafting journal bearings in running condition is discussed. Considerable computational difficulties in non-linear determining the quasi-static equilibrium of the shafting are highlighted. To overcome this problem the approach using two optimization methods (the particle swarm method and the interior point method) in combination with the specially developed relaxation technique is proposed. The developed algorithm allows to calculate marine propulsion shafting bending with taking into account lubrication in all journal bearings and exact form of journal inside bearings, compared to results of most of the publications which consider lubrication only in the aft most stern tube bearing and assume rest of bearings to be represented by points. The calculation results of typical shafting design with four bearings are provided. The significance of taking into account lubrication in all bearings is shown, specifically more exact values of bearings’ reactions, shafting deflections, minimum film thickness and maximum hydrodynamic pressure in the stern tube bearing in case of considering lubrication in all bearings.
PEREMPUAN PECINTA ALAM SEBAGAI WUJUD EKOFEMINISME
Authors: Mahadewi Ni Made Anggita Sastri 
Published: October 2019

ABSTRAK

Tulisan ini berupaya menjelaskan peran perempuan pada organisasi Mahasiswa Pecinta Alam (Mapala) Wanaprastha Dharma, dalam melakukan pelestarian alam. Pada umumnya kegiatan pecinta alam memiliki resiko tinggi dan menuntut kekuatan fisik yang besar, yang identik dimiliki oleh laki-laki. Namun anggota perempuan organisasi Mapala Wanaprastha Dharma mampu melakukan berbagai kegiatan pelestarian alam yang beresiko dengan kekuatan fisik yang memadai. Fenomena tersebut merupakan gambaran konsep ekofeminisme yang menekankan bahwa antara perempuan dan alam memiliki keterkaitan yang tidak dapat dipisahkan, baik oleh kondisi alam itu sendiri maupun oleh stereotipe tentang tubuh perempuan yang dianggap lebih lemah dari laki-laki. Anggota perempuan Mapala Wanaprastha Dharma secara struktural organisasi menempati posisi tinggi, antara lain sebagai ketua umum, sekretaris, maupun ketua pelaksana kegiatan. Melalui penjelasan dalam tulisan ini keterlibatan perempuan dalam pelestarian alam baik yang diimplementasikan secara langsung di lapangan, maupun tidak langsung yakni melalui perencanaan dan program kerja, menunjukan bahwa menjadi hal yang sulit untuk memisahkan perempuan dengan alam.
Kata kunci: Mapala Wanaprastha Dharma, perempuan pecinta alam, ekofeminisme

ABSTRACT
This paper seeks to explain the role of women in the Nature Lovers Student Organization (Mapala) Wanaprastha Dharma, in doing nature conservation. In general the activities of nature lovers have a high risk and demand great physical strength, which is identical to that of men. However, female members of the Mapala Wanaprastha Dharma organization were able to carry out various natural conservation activities which were at risk with adequate physical strength. This phenomenon is an illustration of the concept of eco-feminism which emphasizes that between women and nature has a connection that cannot be separated, both by natural conditions themselves and by stereotypes about the bodies of women who are considered weaker than men. The Mapala Wanaprastha Dharma female member structurally occupies a high position, among others as general chairman, secretary, and chief executive of activities. Through the explanation in this paper, the involvement of women in nature conservation, both directly implemented in the field, and indirectly through planning and work programs, shows that it is difficult to separate women from nature. Keywords: Mapala Wanaprastha Dharma, female nature lover, eco-feminism
English Development as a Second Language in Relation with TV Exposure
Authors: Widiastuti Ni Made Ayu , Shanti Sari Dewi Anak Agung Sagung , Isnu Maharani Sang Ayu 
Published: October 2019

The aims of this study are to know the role of young learner’s parents in choosing good and educating television program for their child, and to describe the effects of TV exposure in their child’s English language development. A five-year-old young learner who lives in Denpasar was observed in 2017. The data were collected by giving a questionnaire to the young learner’s parents in order to get the description of the effects of the television programs to her language development. As it is a following research of the previous research on English vocabulary acquisition, the results of the observation of the young learner and the interview with her parents that have already been done are used to support the analysis of this small research. The collected data were analysed descriptively based on approaches from Barr, et.al. (2010), Christakis (2009), and March (2004) about English language acquisition and language development of young children. The results show that the young learner’s parents have the important role in choosing good and educating television program for her. It can be seen from the choices of cartoon movies as one of the television programs that is educating as well as entertaining for a child in her age, the intensive accompaniment when she was watching the movies, the limitation of television watching time, and also the parents’ assistance in order to help her understand the stories and vocabulary meanings. It is true that good content, context, and the amount of daily TV viewing time as well as parental assistance will be beneficial for the young learner’s second language development in informal learning situation. The effectiveness of watching cartoon movies has led her to gain the positive second language development in her bilingual condition, although English code-switching in Indonesian sentences sometimes occur.
Keywords: SLA, English, language development, TV exposure, cartoon movies
Snowball Throwing in Teaching Grammar
Authors: Apsari Yanuarti 
Published: October 2019

The aims of this study were to describe the implementation of snowball throwing in teaching grammar and to investigate the benefits of applying snowball throwing. The research was conducted at STKIP Siliwangi Bandung. This study employed qualitative research involving one class consisting of second semester students in English department who were taking the subject of foundation of English grammar. The data were obtained from classroom observation and students’ interview. The findings showed that there are seven stages in implementing snowball throwing in teaching grammar. The stages consist of preparing teaching material, forming group, re-explaining the material to the member of the group, formulating question, tossing the ball, answering questions and evaluating teaching and learning process. In addition, the findings also revealed that there are some benefits from applying snowball throwing in teaching grammar such as improving of students’ comprehension in learning grammar, creating enjoyable learning’s atmosphere, increasing students’ vocabulary mastery, developing students’ speaking skill, developing of students’ cooperation skill and increasing of students’ participation in the class.

Keywords: Snowball throwing; benefits; grammar.
HOW TO TRANSLATE AN ACTION VERB PROVIDE INTO BAHASA INDONESIA THROUGH THE NATURAL SEMANTIC METALANGUAGE
Authors: Sudipa I Nengah 
Published: October 2019

Abstract
This study is aimed at mapping the meaning of action verb provide and its translation in Indonesian lexicons. The data sources of this study are two Colours Magazines of Garuda Indonesia, May 2017 and March 2018 editions. In colleting the data, this study applied the observation method and note taking technique. Those data were analyzed using Natural Semantic Metalanguage (NSM) approach proposed by Anna Wierzbicka (1996). Furthermore, the method of analyzing data was descriptive qualitative method. First, each of the data was analyzed to find its meaning configuration. Then, it was followed by the paraphrasing using semantic primitives to show the explication of each lexicon and be able to compare them. The results of this study shows that the action verb provide is translated into five different Indonesian lexicons in the Colours Magazine. The verb and its translations have slight differences shown by the meaning configurations as well as explications. However, they could properly deliver the intended meaning for the Indonesian target readers regarding the sentences they are in.