bluuebunny/crossref_metadata_2025_split huggingface dataset:
Internet of Things Application in Satellite Communication in Power Transmission, Transform and Distribution
Authors: Chuang Dong 
Published: January 2020

Abstract
In the national grid enterprise system, the geographical environment of transmission, substation lines and equipment distribution is very complicated. Transmission lines and substation equipment built in complex environments such as plateaus, forests, canyons and borders are often subjected to earthquakes, floods and blizzards. The threat of mudslide disasters, the ground communication network is greatly affected by extreme natural disasters, and it is impossible to repair and rescue in time when disasters occur. In response to the needs of facility operation and maintenance under emergency anomalies, Tiantong No. 1 satellite is a communication satellite with independent intellectual property rights in China. It has functions such as voice communication, image transmission, positioning, and data reporting. It can set up satellite Internet of Things to realize real-time monitoring and equipment. Conveniences such as inspections and emergency rescues reduce the operation and maintenance costs of the power transmission and transformation process.
Improved Stereo Vision Robot Locating and Mapping Method
Authors: Haige Yu , Fan Yu , Yanxi Wei 
Published: January 2020

Abstract
Vision-based SLAM has an outstanding problem is not work when the camera fast motion, or camera operating environment characterized by scarce. Aiming at this problem, this paper proposes a SLAM method of IMU and vision fusion. This article uses a stereo camera to extract the image ORB feature points. During the camera movement, if the number of extracted feature points is less than a certain threshold and the camera movement cannot be estimated or the estimated camera rotation and translation is greater than a certain threshold, the camera pose is estimated by fusing IMU, Otherwise use feature points to estimate camera pose. This paper uses non-linear optimization methods to perform pose estimation of pure feature points and pose estimation of fused IMU, respectively. The experimental results show that binocular vision SLAM with IMU information can estimate the camera pose more accurately.
A Study on the Sinter Brazing Joint of Powder Metal Components
Authors: Tripathi Pujan , Yang George 
Published: January 2020

Abstract
The research focuses on the development of a new joint method, the sinter brazing of powder metal components. Various kinds of powder metallurgy composition were tested in the sinter brazing joint, mainly to study the operating conditions, strength of the joint. Although each of these processes brings about different results in metal, all of them involve three basic steps: heating, soaking, and cooling. Heat treatment such as heating, soaking, cooling, hardening, tampering has been investigated.
Political Participation of Getasan Community in Semarang Regency Elections in 2015
Authors: Mediatati Nani , Nababan Kristina Roseven 
Published: January 2020

This research aimed to describe the form and the level of political participation of the Getasan district community in the election of Semarang Regency in 2015. Data collection techniques were through interviews, observations, and document studies. Sample research amounted to 182 respondents that were taken from 13 villages in the district of Getasan, and each village was taken 14 respondents. While secondary data of literature studies and studies of documents were both derived from the contestants, the general election commission district, the mass media, and other relevant sources. There were two candidates for the regent and vice-regent period 2015-2020; they were Mundjirin with Ngesti Nugraha that supported by three political parties, and the second, Nur Jatmiko with Mas’ud Ridwan that supported by four political parties. The results show that the form of political participation in the community of Getasan in the election year 2015 can be listed into nine activities, such as participation in one of the political parties, the committee of elections, socialization the candidate, campaign, become a victory team participated in the procurement of polling stations, participated in the voting, participated in the security voting in polling stations, and participated in the process calculation of the vote.
Rhetorical Strategy and Linguistics Features in E-Petition Through Change.org
Authors: Fatkhiyati Nurrahma Restia , Suharno Suharno 
Published: January 2020

The research explored what types and how rhetorical strategy correlated with the linguistics features in e-petitions through Change.org entitled “KPK dalam Bahaya”. The data were e-petitions collected through Change.org. The analysis was holistically descriptive and included in qualitative research. The approach used critical discourse analysis by Fairclough that was using Fairclough’s three-dimensional framework and the strategy of rhetoric by Aristotle. Those theories helped the researcher to find out how the rhetorical strategy and the linguistics features created persuasive meaning. The findings indicate that euphemism, metaphor, connectives, logical connectors, rhetorical questions, and modality support the rhetoric strategy constructing the meaning beyond the words. Through one of the rhetoric strategies, pathos persuades the readers to agree to the argument and sign the e-petitions. Due to the emotional appeals, all of these language instruments help the rhetoric to provoke the readers significantly.
Improvement of surgical treatment in diffuze adenomyosis (a review)
Authors: Gorpenko A. A. , Chuprinin V. D. , Buralkin N. A. , Safronova A. S. 
Published: January 2020

Introduction. Adenomyosis has a significantly negative impact on women’s quality of life, causing abnormal uterine bleeding, dysmenorrhea, and chronic pelvic pain and low quality of life. There are no single theory of pathogenesis, unique prognosis and diagnostic markers for adenomyosis. The definitive treatment for adenomyosis is hysterectomy but is not appropriate for patients who wish to preserve their fertility. In this article presents data about etiology, classification, pathogenesis, clinical manifestation and surgical techniques for the treatment of adenomyosis published in medical–scientific databases.Materials and methods. The review includes data from foreign and Russian articles published in the Pubmed journals on this topic.Results. There are a lot of surgical approaches for adenomyosis; however, there is no any universal approach and management guideline for these patients.Conclusion. Adenomyosis – if multifactorial disease. There is no single pathogenesis theory. The clinical picture of adenomyosis varies from asymptomatic to severe pain. The management of adenomyosis is complex and should guide personally for each patient. All techniques and options should be considered and discussed with the patient.
Biological decolourization of textile industry wastewater by a developed bacterial consortium
Authors: Madhushika Hewayalage Gimhani , Ariyadasa Thilini U. , Gunawardena Sanja H. P. 
Published: January 2020

Abstract
Most currently employed textile effluent decolourization methods use physical and chemical processes where dyes do not get degraded instead concentrated or transferred into a solid phase. Therefore, further treatment processes are required to destroy dyes from the environment. In contrast, biological decolourization may result in degradation of the dye structure due to microbial activities and hence biological processes can be considered environmentally friendly. In the present study, bacterial strains with dye decolourization potential were isolated from the natural environment and their ability to decolourize four different reactive textile dyes was studied individually and in a bacterial consortium. The developed bacterial consortium composed with Proteus mirabilis, Morganella morganii and Enterobacter cloacae indicated more than 90% color removals for all four dyes and optimum decolourization of the dye mixture was observed at 40 °C and pH 7. The developed bacterial consortium decolourized 60% of dyes in textile industry effluent at 35 °C and pH 7 showing their ability to endure in highly complex and toxic environments and application in textile industry wastewaters.
Mapeamento de competências: necessidades de aprimoramento de analistas periciais em contabilidade do Ministério Público Federal
Authors: Prates Ariel , Sallaberry Jonatas Dutra , Flach Leonardo , Peleias Ivam Ricardo , Souza Romina Batista de Lucena 
Published: January 2020

Objetivo: O estudo tem como objetivo analisar as competências dos analistas da área pericial contábil lotados no Ministério Público Federal (MPF), de forma a apresentar por nível de importância aquelas que possuem maior necessidade de aprimoramento.
Metodologia: O desenvolvimento da pesquisa ocorreu por meio da tipologia descritiva, com abordagem quantitativa. A técnica empregada foi pesquisa survey, a partir de um questionário estruturado com 37 questões, aplicados em escala tipo Likert de sete pontos. No instrumento foram apresentadas questões sobre a importância, o domínio de competências e seu impacto no desempenho profissional.
Resultados: Os resultados indicam que apenas quatro competências possuem domínio satisfatório por parte dos respondentes, e que cinco competências carecem maior aprimoramento: capacitação continuada, técnicas de investigação de fraudes, redação, conhecimento jurídico e pensar como malfeitor. As competências comportamentais foram consideradas mais importantes do que as técnicas. Ainda assim, algumas competências importantes no contexto internacional tiveram médias baixas no contexto brasileiro.
Contribuições do Estudo: O estudo permite conhecer as competências dos analistas periciais do MPF sob os aspectos de importância, domínio e impacto no desempenho profissional. Os resultados podem ser empregados para o desenvolvimento de ações de capacitação na instituição da amostra bem como para outras instituições que dispõe de quadro semelhante. O estudo também pode ser replicado como diagnóstico para outras instituições e quadros de profissionais de perícia contábil e forense, servindo de parâmetro de comparabilidade.
PERSPECTIVAS TEÓRICAS SOBRE DESENVOLVIMENTO REGIONAL
Authors: Vasconcelos Lucas Henrique Campos , Antonello Ideni Terezinha 
Published: January 2020

O debate sobre o desenvolvimento regional desigual se consolidou como um tema de grande importância na literatura que aborda o crescimento e o desenvolvimento econômico. Teorias foram e são formuladas com a finalidade de explicar e corrigir os desequilíbrios regionais, alcançando influência tanto no âmbito do ambiente acadêmico quanto no das políticas públicas. A esse respeito, o objetivo deste artigo é apresentar uma síntese de algumas abordagens teóricas que trabalharam, direta ou indiretamente, com o tema, desde as clássicas até às contemporâneas. Para isso, a produção teórica foi divida em três partes, sendo elas: teorias espaciais ou da localização, teorias clássicas de desenvolvimento regional e abordagens recentes de desenvolvimento regional. Destaca-se que essa divisão foi realizada conforme propõe a maioria dos estudiosos da área, visto que as teorias agrupadas possuem linhas de pensamentos e influências semelhantes. Ou seja, não se buscou discorrer as teorias de forma cronológica.
Genistein: Its Role in Breast Cancer Growth and Metastasis
Authors: Mukund Vidya 
Published: January 2020

Background:
Genistein being a phytoestrogen imitates the characteristics of estrogen, which can be useful
to treat conditions by reducing the estrogen levels at the time of menopause, osteoporosis and high risk for breast
cancer.

Objective:
The superior binding of genistein to ERβ might help in reducing breast malignancy risk.

Conclusion:
Genistein induces cell cycle arrest, anti-metastatic properties and ultimately affects the breast cancer
cell growth by multiple mechanisms. Genistein-mediated anti-proliferative or anti-growth effects are usually observed
at higher concentrations. These signaling pathways involve the decrease of NF-κB, HIF-1α, VEGF, and an
increase of tumor suppressor p21. This will provide further insight into understanding the biology of transcription
factors NF-κB, and HIF-1α in breast cancer.
The Effects of Lauric Acid on IPEC-J2 Cell Differentiation, Proliferation, and Death
Authors: Yang Yuan , Huang Jin , Li Jianzhong , Yang Huansheng , Yin Yulong 
Published: January 2020

Background:
Lauric acid (LA) has antimicrobial effects and the potential to replace
antibiotics in feeds to prevent postweaning diarrhea and increase overall swine productivity. The
effects of lauric acid on the intestinal epithelial cells remain unclear.

Materials and Methods:
This study investigates the effects of LA on pig intestinal epithelial cell line
(IPEC-J2) differentiation, proliferation, and death and explores its underlying mechanisms. It was
found that 0.25-0.1 mM LA promoted IPEC-J2 cell differentiation. At 1 mM or higher concentrations,
it induced IPEC-J2 cell viability decreases, lipid accumulation, cell proliferation inhibition, and cell
apoptosis. The cell death induced did not depend on caspase pathways.

The data demonstrated that LA induced the IPEC-J2 cell autophagy and impaired autophagy flux
and autophagy plays a role in protecting against LA induced-cell death. p38 MAPK inhibitor
SB202190 attenuated LA-reduced IPEC-J2 cell viability. This associated with an increase in
autophagy level and a decrease in lipid accumulations and FABPI levels.

Conclusion:
Conclusion: In summary, LA promoted the IPEC-J2 cell apoptosis depends on the p38 MAPK
pathways and may involve autophagy and TG metabolism regulation.
MicroRNA (miR)-429 Promotes Inflammatory Injury by Targeting Kruppel-like Factor 4 (KLF4) in Neonatal Pneumonia
Authors: Zhang Lan , Yan HuanLi , Wang Huiping , Wang Li , Bai Boling , Ma Yingjun , Tie Yingchun , Xi Zhaoxia 
Published: January 2020

Background:
Neonatal pneumonia is a common disease in the neonatal period with a
high incidence and death. This study aimed to investigate the molecular mechanism and effect of
microRNA (miR)-429 in neonatal pneumonia.

Methods:
The peripheral blood was collected from neonatal pneumonia and healthy patients,
respectively. Human lung fibroblast WI-38 cells were treated with lipopolysaccharide (LPS) to
establish neonatal pneumonia cell model. Then, the miR-429 expression was detected by quantitative
real-time polymerase chain reaction (qRT-PCR). In addition, the relationship between miR-
429 and kruppel-like factor 4 (KLF4) was confirmed by dual luciferase reporter assay. Cell viability,
the level of interleukin 6 (IL-6), IL-1β and tumor necrosis factor α (TNF-α) and apoptosis were
measured by Cell Counting Kit-8 (CCK-8), enzyme linked immunosorbent assay (ELISA) and
flow cytometry. Meanwhile, apoptosis and nuclear factor kappa-B (NF-κB) pathway related proteins
expression were analyzed by western blot.

Results:
MiR-429 expression level was increased in neonatal peripheral blood and LPS-stimulated
WI-38 cells. Then, miR-429 overexpression increased apoptosis, the level of IL-6, IL-1β, TNF-α,
Bax and cleaved caspase-3, while reduced cell viability in LPS-stimulated WI-38 cells. Besides,
KLF4 was identified as the target gene of miR-429, and reversed the changes caused by miR-429
overexpression. Finally, miR-429 suppressor down-regulated p-NF-κB level in LPS-stimulated
cells and KLF4 knockdown reversed these reductions.

Conclusion:
MiR-429 promotes inflammatory injury, apoptosis and activates the NF-κB signaling
pathway by targeting KLF4 in neonatal pneumonia, and then these results provide evidence for
clinical diagnosis and treatment for neonatal pneumonia.
Pragmatic Analysis of Dyslipidemia Involvement in Coronary Artery Disease: A Narrative Review
Authors: Mihăilă Romeo-Gabriel 
Published: January 2020

Background:
Dyslipidemia is the main factor involved in the occurrence and progression
of coronary artery disease.

Objective:
The research strategy is aimed at analyzing new data on the pathophysiology of dyslipidemia
involvement in coronary artery disease, the modalities of atherogenic risk estimation and
therapeutic advances.

Method:
Scientific articles published in PubMed from January 2017 to February 2018 were
searched using the terms "dyslipidemia" and "ischemic heart disease".

Results:
PCSK9 contributes to the increase in serum levels of low-density lipoprotein-cholesterol
and lipoprotein (a). The inflammation is involved in the progression of hyperlipidemia and atherosclerosis.
Hypercholesterolemia changes the global cardiac gene expression profile and is thus involved
in the increase of oxidative stress, mitochondrial dysfunction, and apoptosis initiated by inflammation.
Coronary artery calcifications may estimate the risk of coronary events. The cardioankle
vascular index evaluates the arterial stiffness and correlates with subclinical coronary atherosclerosis.
The carotid plaque score is superior to carotid intima-media thickness for risk stratification
in patients with familial hypercholesterolemia and both can independently predict coronary artery
disease. The lipoprotein (a) and familial hypercholesterolemia have a synergistic role in predicting
the risk of early onset and severity of coronary atherosclerosis. A decrease in atherosclerotic
coronary plaque progression can be achieved in patients with plasma LDL-cholesterol levels below
70 mg/dL. A highly durable RNA interference therapeutic inhibitor of PCSK9 synthesis could be a
future solution.

Conclusion:
The prophylaxis and treatment of coronary artery disease in a dyslipidemic patient
should be based on a careful assessment of cardio-vascular risk factors and individual metabolic
particularities, so it may be personalized.
Therapeutic Journey of Pyrazolines as EGFR Tyrosine Kinase Inhibitors: An Insight into Structure-Activity Relationship
Authors: Singh Navdeep , Gupta Monika 
Published: January 2020

Background:
Pyrazolines are five-membered heterocycles with two adjacent nitrogen atoms
present in the ring and they have attracted many researchers all over the world to assess their potential
therapeutic significance. Pyrazolines are known for their crucial role in numerous diseases like cancer
via various mechanisms. Pyrazoline and its derivatives have been found to have potent anticancer activity
by inhibiting EGFR (Epidermal Growth Factor Receptor Tyrosine Kinase) and other types of RTKs.
Rapid advances in the understanding of cellular signaling by EGFR in normal and malignant cells have
brought to light the EGFR as a selective anticancer target. The review enlists some recently developed
pyrazolines as EGFR tyrosine kinase inhibitor along with their structure-activity relationships.

Methods:
The structure-activity relationship of different pyrazoline derivatives was discussed along
with their epidermal growth factor receptor inhibitory activity. Both review and research articles have
been considered and cited in the paper.

Results:
Pyrazolines have assisted medicinal chemistry by their diverse biological activities which make
them a beneficial scaffold. The structure-activity relationship studies on pyrazolines revealed that the
structural characteristics and different substitutions on pyrazoline ring alter the EGFR inhibitory activity.

Conclusion:
In the present review, pyrazoline derivatives with EGFR kinase inhibitory activity are described
based on their structure-activity relationships based on their structural substitution pattern
around the pyrazoline scaffold.
Densely Dilated Spatial Pooling Convolutional Network Using Benign Loss Functions for Imbalanced Volumetric Prostate Segmentation
Authors: Liu Qiuhua , Fu Min , Jiang Hao , Gong Xinqi 
Published: January 2020

Background:
The high incidence rate of prostate disease poses a requirement of accurate early
detection. Magnetic Resonance Imaging (MRI) is one of the main imaging methods used for prostate cancer
detection so far, but it has problems of imbalance and variation in appearance, therefore, automated prostate
segmentation is still challenging.

Objective:
Aiming to accurately segment the prostate from MRI, the focus was on designing a unique network
with benign loss functions.

Methods:
A novel Densely Dilated Spatial Pooling Convolutional Network (DDSP ConNet) in an encoderdecoder
structure, with a unique DDSP block was proposed. By densely combining dilated convolution and
global pooling layers, the DDSP block supplies coarse segmentation results and preserves hierarchical contextual
information. Meanwhile, the DSC and Jaccard loss were adopted to train the DDSP ConNet. And it was proved
theoretically that they have benign properties, including symmetry, continuity, and differentiability on the
parameters of the network.

Results:
Extensive experiments have been conducted to corroborate the effectiveness of the DDSP ConNet with
DSC and Jaccard loss on the MICCAI PROMISE12 challenge dataset. In the test dataset, the DDSP ConNet
achieved a score of 85.78.

Conclusion:
In the conducted experiments, DDSP network with DSC and Jaccard loss outperformed most of
the other competitors on the PROMISE12 dataset. Therefore, it has a better ability to extract hierarchical features
and solve the imbalanced medical image problem.
Ultrasound Assisted Synthesis of 2-Substituted Benzofurans via One-Pot and Sequential Method: Their In Vitro Evaluation
Authors: Rao Bodapati V.D. , Vardhini Suryadevara V. , Kolli Deepti , Rao Mandava V.B. , Pal Manojit 
Published: January 2020

Background:
The 2-substituted benzofuran framework has attracted enormous attention due to its
presence in a range of bioactive compounds and natural products. While various methods for the synthesis of 2-
substituted benzofuran derivatives are known, several of them suffer from certain drawbacks.

Objective:
The main objective of this work was to explore a series of 2-(het)aryl substituted benzofurans derivatives
for their cytotoxic properties against cancer cell lines in vitro.

Methods:
In our efforts, we have developed a one-pot synthesis of this class of compounds via sequential C-C
coupling followed by C-Si bond cleavage and subsequent tandem C-C/C-O bond-forming reaction under ultrasound
irradiation. The methodology involved coupling of (trimethylsilyl)acetylene with iodoarenes in the presence
of 10% Pd/C-CuI-PPh3-Et3N in MeOH followed by treating the reaction mixture with K2CO3 in aqueous
MeOH and finally coupling with 2-iodophenol. A variety of 2-substituted benzofurans were synthesized using
this methodology in good yield. All the synthesized compounds were tested in vitro against two cancer cell
lines, e.g. MDAMB-231 and MCF-7 cell lines subsequently against SIRT1.

Results:
The benzofuran derivative 3m showed encouraging growth inhibition of both MDAMB-231 and MCF-
7 cell lines and significant inhibition of SIRT1. The compound 3m also showed a concentration-dependent
increase in the acetylation of p53.

Conclusion:
Our efforts not only accomplished a one-pot and direct access to 2-(het)aryl substituted benzofurans
but also revealed that the benzofuran framework presented here could be a potential template for the
identification of potent inhibitors of SIRT1.