bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dignifying, Restoring, and Reimagining International Law and Justice Through Connections with Arts and Culture
Authors: Bennoune Karima 
Published: March 2020

This symposium provides a critical opportunity for international legal scholars to engage with the value and power of certain aspects of culture. The successive holders of the UN mandate on cultural rights have declined to define culture, instead taking a holistic, inclusive approach to its meanings, including inter alia diverse forms of artistic and cultural expressions, languages, worldviews, practices, and cultural heritage. Cultural rights—including the right to take part in cultural life without discrimination, the right to access and enjoy cultural heritage, and freedom of artistic expression—are a core part of the universal human rights framework. They are vital in and of themselves and protect key aspects of the human experience, but they have also been increasingly recognized as important elements of accessing justice and responding to atrocities and as “fundamental to creating and maintaining peaceful and just societies and to promoting enjoyment of other universal human rights.” The artistic and cultural expressions which result from the exercise of these rights likewise have inherent value and can also play significant roles in achieving basic goals of international law and human rights. As I noted in a report to the UN Human Rights Council in my capacity as UN Special Rapporteur in the field of cultural rights:Humanity dignifies, restores and reimagines itself through creating, performing, preserving and revising its cultural and artistic life . . . . Cultural heritage, cultural practices and the arts are resources for marshalling attention to urgent concerns, addressing conflicts, reconciling former enemies, resisting oppression, memorializing the past, and imagining and giving substance to a more rights-friendly future.
Data protection issues in cross-border interoperability of Electronic Health Record systems within the European Union
Authors: Bincoletto Giorgia 
Published: March 2020

AbstractThis study investigates the data protection concerns arising in the context of the cross-border interoperability of Electronic Health Record (EHR) systems in the European Union. The article first introduces the policies on digital health and examines the related interoperability issues. Second, the work analyses the latest Recommendation of the European Commission on this topic. Then, the study discusses the rules and the obligations settled by the General Data Protection Regulation to be taken into account when developing interoperable EHRs. According to the data protection by design and by default provision, EHR systems should be designed ex ante to guarantee data protection rules.
Methionine-balanced diets improve cattle performance in fattening young bulls fed high-forage diets through changes in nitrogen metabolism
Authors: Cantalapiedra-Hijar G. , Ortigues-Marty I. , Sepchat B. , Titgemeyer E. , Bahloul L. 
Published: March 2020

AbstractRuminants fed high-forage diets usually have a low feed efficiency, and their performances might be limited by methionine (Met) supply. However, the INRA feeding system for growing cattle does not give recommendation for this amino acid (AA). This study aimed to assess the effects of Met-balanced diets on animal performance and N metabolism in young bulls fed high-forage diets formulated at or above protein requirements. Four diets resulting from a factorial arrangement of two protein levels (Normal (13·5 % crude protein) v. High (16·2 % crude protein)) crossed with two Met concentrations (unbalanced (2·0 % of metabolisable protein) v. balanced (2·6 % of metabolisable protein)) were tested on thirty-four fattening Charolais bulls for 7 months before slaughter. Animal growth rate was greater in Met-balanced diets (+8 %; P = 0·02) with a trend for a greater impact in High v. Normal protein diets (P = 0·10). This trend was observed in lower plasma concentrations of branched-chain AA only when Met supplementation was applied to the Normal protein diet (P ≤ 0·06) suggesting another co-limiting AA at Normal protein level. Feed conversion efficiency and N use efficiency were unaffected by Met supplementation (P > 0·05). However, some plasma indicators suggested a better use of AA when High protein diets were balanced v. unbalanced in Met. The proportion of total adipose tissue in carcass increased (+5 percent units; P = 0·03), whereas that of muscle decreased on average 0·8 percent units (P = 0·05) in Met-balanced diets. Our results justify the integration of AA into dietary recommendations for growing cattle.
“Their debts follow them into the afterlife”: German Settlers, Ethnographic Knowledge, and the Forging of Coffee Capitalism in Nineteenth-Century Guatemala
Authors: Gibbings Julie 
Published: March 2020

AbstractGerman coffee planters in nineteenth-century Alta Verapaz, Guatemala were also ethnographers, archaeologists, and geographers who published their works in Germany, the United States, and Guatemala. Their published works, as well as coffee plantation records, government correspondence, judicial records and other archival materials reveal how German coffee planters-cum-ethnographers drew upon ethnographic knowledge and representations to forge a reliable labor force. Like ethnographers in Britain's colonies, German settlers in Alta Verapaz understood the potential symmetry between ethnography and the governance of indigenous peoples. Their ethnographic knowledges also push us to reconsider distinctions drawn between German cosmopolitan ethnographic traditions and British functionalist ones and demonstrate how ethnographic knowledge and cultural difference could be deployed to forge new kinds of racial capitalism. In Guatemala, the intimate relationship between the rise of capitalism and ethnography shaped the anti-communism of mid-twentieth-century anthropology in the region.
Non-pecuniary damages before the European Court of Human Rights: Forget the victim; it’s all about the state
Authors: Fikfak Veronika 
Published: March 2020

AbstractThis article studies how the European Court of Human Rights (ECtHR, the Court) adjusts damages for human rights violations. The article empirically analyses 13 years of ECtHR’s case law in relation to Articles 2 (right to life), 3 (torture, inhuman and degrading treatment), and 5 (arbitrary detention) of the European Convention on Human Rights (ECHR, the Convention). The goal is to understand whether the statements made by the Court about the aims pursued through just satisfaction are confirmed in practice. Through an empirical quantitative study relating to non-pecuniary damages, the article analyses the practice of the Court in awarding non-pecuniary damages for human rights violations and compares it to the competing visions of the ECtHR’s function. In particular, I am interested in determining whether just satisfaction is aimed at redressing the suffering of the victim, her circumstances and vulnerability, or whether the focus is more on the respondent state, its conduct and its past human rights record. The answers to these questions will contribute to the debate whether the ECtHR’s role is one of delivering ‘individual justice’ or whether the Court is – as an international court enforcing an international treaty – focused on the ‘state’.
Post-operative acute kidney injury is associated with a biomarker of acute brain injury after paediatric cardiac surgery
Authors: Parsons Michael , Greenberg Jason , Parikh Chirag , Brown Jeremiah , Parker Devin , Zhu Jie , Vricella Luca , Everett Allen D. 
Published: March 2020

AbstractIntroduction:Children with CHD who undergo cardiopulmonary bypass are at an increased risk of acute kidney injury. This study evaluated the association of end-organ specific injury plasma biomarkers for brain: glial fibrillary acidic protein and heart: Galectin 3, soluble suppression of tumorgenicity 2, and N-terminal pro b-type natriuretic peptide with acute kidney injury in children undergoing cardiopulmonary bypass.Materials and Methods:We enrolled consecutive children undergoing cardiac surgery with cardiopulmonary bypass. Blood samples were collected pre-bypass in the operating room and in the immediate post-operative period. Acute kidney injury was defined as a rise of serum creatinine ≥50% from pre-operative baseline within 7 days after surgery.Results:Overall, 162 children (mean age 4.05 years, sd 5.28 years) were enrolled. Post-operative acute kidney injury developed in 55 (34%) children. Post-operative plasma glial fibrillary acidic protein levels were significantly higher in patients with acute kidney injury (median 0.154 (inter-quartile range 0.059–0.31) ng/ml) compared to those without acute kidney injury (median 0.056 (inter-quartile range 0.001–0.125) ng/ml) (p = 0.043). After adjustment for age, weight, and The Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery category, each natural log increase in post-operative glial fibrillary acidic protein was significantly associated with a higher risk for subsequent acute kidney injury (adjusted odds ratio glial fibrillary acidic protein 1.25; 95% confidence interval 1.01–1.59). Pre/post-operative levels of galectin 3, soluble suppression of tumorgenicity 2, and N-terminal pro b-type natriuretic peptide did not significantly differ between patients with and without acute kidney injury.Conclusions:Higher plasma glial fibrillary acidic protein levels measured in the immediate post-operative period were independently associated with subsequent acute kidney injury in children after cardiopulmonary bypass. Elevated glial fibrillary acidic protein likely reflects intraoperative brain injury which may occur in the context of acute kidney injury-associated end-organ dysfunction.
Healthful and less-healthful foods and drinks from storefront and non-storefront businesses: implications for ‘food deserts’, ‘food swamps’ and food-source disparities
Authors: Lucan Sean C , Maroko Andrew R , Patel Achint N , Gjonbalaj Ilirjan , Elbel Brian , Schechter Clyde B 
Published: March 2020

AbstractObjective:Conceptualisations of ‘food deserts’ (areas lacking healthful food/drink) and ‘food swamps’ (areas overwhelm by less-healthful fare) may be both inaccurate and incomplete. Our objective was to more accurately and completely characterise food/drink availability in urban areas.Design:Cross-sectional assessment of select healthful and less-healthful food/drink offerings from storefront businesses (stores, restaurants) and non-storefront businesses (street vendors).Setting:Two areas of New York City: the Bronx (higher-poverty, mostly minority) and the Upper East Side (UES; wealthier, predominantly white).Participants:All businesses on 63 street segments in the Bronx (n 662) and on 46 street segments in the UES (n 330).Results:Greater percentages of businesses offered any, any healthful, and only less-healthful food/drink in the Bronx (42·0 %, 37·5 %, 4·4 %, respectively) than in the UES (30 %, 27·9 %, 2·1 %, respectively). Differences were driven mostly by businesses (e.g. newsstands, gyms, laundromats) not primarily focused on selling food/drink – ‘other storefront businesses’ (OSBs). OSBs accounted for 36·0 % of all food/drink-offering businesses in the Bronx (more numerous than restaurants or so-called ‘food stores’) and 18·2 % in the UES (more numerous than ‘food stores’). Differences also related to street vendors in both the Bronx and the UES. If street vendors and OSBs were not captured, the missed percentages of street segments offering food/drink would be 14·5 % in the Bronx and 21·9 % in the UES.Conclusions:Of businesses offering food/drink in communities, OSBs and street vendors can represent substantial percentages. Focusing on only ‘food stores’ and restaurants may miss or mischaracterise ‘food deserts’, ‘food swamps’, and food/drink-source disparities between communities.
Folate, alcohol, ADH1B and ALDH2 and colorectal cancer risk
Authors: Seol Ju Eun , Kim Jeongseon , Lee Bong-Hwa , Hwang Dae-Yong , Jeong Jinyoung , Lee Hun-Jae , Ahn Yoon-Ok , Lee Jung Eun , Kim Dong-Hyun 
Published: March 2020

AbstractObjective:There is limited evidence on the interaction by alcohol dehydrogenase 2 (ADH1B) (rs1229984) and aldehyde dehydrogenase 2 (ALDH2) (rs671) regarding the associations of alcohol and a methyl diet (low folate and high alcohol intake) with cancer risk, partly because of rare polymorphisms in Western populations.Design:In a case–control study, we estimated the ORs and 95 % CIs to evaluate the associations of ADH1B and ALDH2 genotypes with colorectal cancer (CRC) and the joint association between methyl diets and ADH1B and ALDH2 polymorphisms with CRC risk using logistic regression models.Setting:A hospital-based case–control study.Participants:In total, 1001 CRC cases and 899 cancer-free controls admitted to two university hospitals.Results:We found that alcohol intake increased the risk of CRC; OR (95 % CI) was 2·02 (1·41, 2·87) for ≥60 g/d drinkers compared with non-drinkers (Ptrend < 0·001). The associations for two polymorphisms with CRC were not statistically significant. However, we found a potential interaction of ALDH2 with methyl diets and CRC. We observed a 9·08-fold (95 % CI 1·93, 42·60) higher risk of CRC for low-methyl diets compared with high-methyl diets among individuals with an A allele of ALDH2, but the association was not apparent among those with ALDH2 GG (Pinteraction = 0·02).Conclusions:Our data support the evidence that gene–methyl diet interactions may be involved in CRC risk in East Asian populations, showing that a low-methyl diet increased the risk of CRC among individuals with an A allele of ALDH2.
ON DEL PEZZO FIBRATIONS IN POSITIVE CHARACTERISTIC
Authors: Bernasconi Fabio , Tanaka Hiromu 
Published: March 2020

AbstractWe establish two results on three-dimensional del Pezzo fibrations in positive characteristic. First, we give an explicit bound for torsion index of relatively torsion line bundles. Second, we show the existence of purely inseparable sections with explicit bounded degree. To prove these results, we study log del Pezzo surfaces defined over imperfect fields.
Guided electromagnetic waves for damage detection and localization in metallic plates: numerical and experimental results
Authors: Moll Jochen 
Published: March 2020

AbstractElectromagnetic waves in the microwave and millimeter-wave frequency range are used in non-destructive testing and structural health monitoring applications to detect material defects such as delaminations, cracks, or inclusions. This work presents a sensing concept based on guided electromagnetic waves (GEW), in which the waveguide forms a union with the structure to be inspected. Exploiting ultra-wideband signals a surface defect in the area under the waveguide can be detected and accurately localized. This paper presents numerical and experimental GEW results for a straight waveguide focusing on the detection of through holes and cracks with different orientation. It was found that the numerical model qualitatively replicates the experimental S-parameter measurements for holes of different diameters. A parametric numerical study indicates that the crack parameters such as its orientation and width has a significant influence on the interaction of the incident wave with the structural defect. On top, a numerical study is performed for complex-shaped rectangular waveguides including several waveguide bends. Besides a successful damage detection, the damage position can also be precisely determined with a maximum localization error of less than 3%.
Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus
Authors: Popov Alexander , Denisov Pavel , Bychkov Maxim , Brazhe Alexey , Lyukmanova Ekaterina , Shenkarev Zakhar , Lazareva Natalia , Verkhratsky Alexei , Semyanov Alexey 
Published: March 2020

AbstractCalorie-restricted (CR) diet has multiple beneficial effects on brain function. Here we report morphological and functional changes in hippocampal astrocytes in 3-months-old mice subjected to 1 month of the diet. Whole-cell patch-clamp recordings were performed in the CA1 stratum (str.) radiatum astrocytes of hippocampal slices. The cells were also loaded with fluorescent dye through the patch pipette. CR did not affect the number of astrocytic branches but increased the volume fraction (VF) of distal perisynaptic astrocytic leaflets. The astrocyte growth did not lead to a decrease in the cell input resistance, which may be attributed to a decrease in astrocyte coupling through the gap junctions. Western blotting revealed a decrease in the expression of Cx43 but not Cx30. Immunocytochemical analysis demonstrated a decrease in the density and size of Cx43 clusters. Cx30 cluster density did not change, while their size increased in the vicinity of astrocytic soma. CR shortened K+ and glutamate transporter currents in astrocytes in response to 5 × 50 Hz Schaffer collateral stimulation. However, no change in the expression of astrocytic glutamate transporter 1 (GLT-1) was observed, while the level of glutamine synthetase (GS) decreased. These findings suggest that enhanced enwrapping of synapses by the astrocytic leaflets reduces glutamate and K+ spillover. Reduced spillover led to a decreased contribution of extrasynaptic N2B containing N-methyl-D-aspartate receptors (NMDARs) to the tail of burst-induced EPSCs. The magnitude of long-term potentiation (LTP) in the glutamatergic CA3–CA1 synapses was significantly enhanced after CR. This enhancement was abolished by N2B-NMDARs antagonist. Our findings suggest that astrocytic morphofunctional remodeling is responsible for enhanced synaptic plasticity, which provides a basis for improved learning and memory reported after CR.
3D printing of conducting polymers
Authors: Yuk Hyunwoo , Lu Baoyang , Lin Shen , Qu Kai , Xu Jingkun , Luo Jianhong , Zhao Xuanhe 
Published: March 2020

AbstractConducting polymers are promising material candidates in diverse applications including energy storage, flexible electronics, and bioelectronics. However, the fabrication of conducting polymers has mostly relied on conventional approaches such as ink-jet printing, screen printing, and electron-beam lithography, whose limitations have hampered rapid innovations and broad applications of conducting polymers. Here we introduce a high-performance 3D printable conducting polymer ink based on poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) for 3D printing of conducting polymers. The resultant superior printability enables facile fabrication of conducting polymers into high resolution and high aspect ratio microstructures, which can be integrated with other materials such as insulating elastomers via multi-material 3D printing. The 3D-printed conducting polymers can also be converted into highly conductive and soft hydrogel microstructures. We further demonstrate fast and streamlined fabrications of various conducting polymer devices, such as a soft neural probe capable of in vivo single-unit recording.
Interleukin 17A: a Janus-faced regulator of osteoporosis
Authors: Scheffler J. M. , Grahnemo L. , Engdahl C. , Drevinge C. , Gustafsson K. L. , Corciulo C. , Lawenius L. , Iwakura Y. , Sjögren K. , Lagerquist M. K. , Carlsten H. , Ohlsson C. , Islander U. 
Published: March 2020

AbstractInterleukin (IL)-17A is a well-described mediator of bone resorption in inflammatory diseases, and postmenopausal osteoporosis is associated with increased serum levels of IL-17A. Ovariectomy (OVX) can be used as a model to study bone loss induced by estrogen deficiency and the role of IL-17A in osteoporosis development has previously been investigated using various methods to inhibit IL-17A signaling in this model. However, the studies show opposing results. While some publications reported IL-17A as a mediator of OVX-induced osteoporosis, others found a bone-protective role for IL-17 receptor signaling. In this study, we provide an explanation for the discrepancies in previous literature and show for the first time that loss of IL-17A has differential effects on OVX-induced osteoporosis; with IL-17A being important for cortical but not trabecular bone loss. Interestingly, the decrease in trabecular bone after OVX in IL-17A knock-out mice, was accompanied by increased adipogenesis depicted by elevated leptin levels. Additionally, the bone marrow adipose tissue expanded, and the bone-turnover decreased in ovariectomized mice lacking IL-17A compared to ovariectomized WT mice. Our results increase the understanding of how IL-17A signaling influences bone remodeling in the different bone compartments, which is of importance for the development of new treatments of post-menopausal osteoporosis.
Organ ischemia during partial resuscitative endovascular balloon occlusion of the aorta: Dynamic 4D Computed tomography in swine
Authors: Matsumura Yosuke , Higashi Akiko , Izawa Yoshimitsu , Hishikawa Shuji , Kondo Hiroshi , Reva Viktor , Oda Shigeto , Matsumoto Junichi 
Published: March 2020

AbstractResuscitative endovascular balloon occlusion of the aorta (REBOA) increases proximal pressure, and simultaneously induces distal ischemia. We aimed to evaluate organ ischemia during partial REBOA (P-REBOA) with computed tomography (CT) perfusion in a swine model. The maximum balloon volume was recorded as total REBOA when the distal pulse pressure ceased. The animals (n = 4) were scanned at each 20% of the maximum balloon volume, and time-density curve (TDC) were analysed at the aorta, portal vein (PV), liver parenchyma, and superior mesenteric vein (SMV, indicating mesenteric perfusion). The area under the TDC (AUTDC), the time to peak (TTP), and four-dimensional volume-rendering images (4D-VR) were evaluated. The TDC of the both upper and lower aorta showed an increased peak and delayed TTP. The TDC of the PV, liver, and SMV showed a decreased peak and delayed TTP. The dynamic 4D-CT analysis suggested that organ perfusion changes according to balloon volume. The AUTDC at the PV, liver, and SMV decreased linearly with balloon inflation percentage to the maximum volume. 4D-VR demonstrated the delay of the washout in the aorta and retrograde flow at the inferior vena cava in the highly occluded status.
Editorial
Authors: Ewertsen Caroline 
Published: March 2020

Dear Colleagues,Europe is severely hit by the virus SARS-CoV-2 and most countries report
increasing numbers of people affected by COVID-19. WHO has declared it a
pandemic, many countries have introduced severe restrictions on travelling and
thousands of people around Europe are in quarantine. Currently, the most
severely affected European country is Italy, which also experienced some of the
first European cases.
Über die heilende Kraft des echten
Gesprächs
Authors: Maio Giovanni 
Published: March 2020

ZusammenfassungFür den Umgang mit hilfsbedürftigen Menschen in Medizin und
Pflege ist das Gespräch das Zentrale, denn mag das Gespräch auch
nicht lebensrettend sein, so bleibt es gleichwohl überlebensnotwendig.
Das Gespräch ist in sich wertvoll, trägt in sich einen Wert,
weil das Gespräch selbst spricht. Allein dass man mit jemandem spricht,
bringt man das Eigentliche schon zum Ausdruck, nämlich dass der andere
Bedeutung hat. Weil das Gespräch Vermittlung und Ausdruck zugleich ist,
wird auch erklärbar, warum gerade das Gespräch Wirklichkeit
verändert, und dies oft in einem nachhaltigeren und tieferen Sinn, als
es ein Medikament je könnte.