bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functionalized Biogenic Nanoparticles for use in Emerging Biomedical Applications: A Review
Authors: Das Samvidha , Bhardwaj Aman , Pandey Lalit M. 
Published: December 2020

Background:
The widespread uses of nanomaterials for healthcare and biomedical applications such as their
anti-cancer activity, anti-oxidant activity and antimicrobial activity, have been avidly studied in recent decades. Owing to
the cytotoxicity and harmful by-product generation associated with chemical reagents, plant and microbial-based approach
have been preferred for the synthesis purposes.

Results:
These synthesized nanoparticles possess characteristic properties attributed to their nano-size compared to their
macroscopic counterparts. Further, the functionalization of nanomaterials via chemical, physical and biofunctionalization
techniques improves the intrinsic, tactile, and associated properties of materials and devices. The functionalized nanomaterials have been explored for the improved colloidal stability, development of smart nanocapsules, DNA-nanoparticles conjugates, protein-nanoparticles conjugates and nano-antibiotics.

Conclusion:
In this review, the synthesis of biogenic nanoparticles, their properties and applications are explored, and its
surface modification and implications towards improved properties are emphasized.
Cidade em Disputa: Narrativas do passo dos negros em Pelotas, RS
Authors: Da Silveira Melina Monks , Alfonso Louise Prado , Da Cruz Larissa Osterberg 
Published: December 2020

Este ensaio apresenta a região do Passo dos Negros, localizada em Pelotas – RS. A localidade representa um lugar de luta e resistência negra ao longo do tempo. Hoje trata-se de uma área em conflito, que está passando por um processo de especulação imobiliária e a comunidade corre risco de ser removida do local. Nas narrativas e na paisagem percebemos um Passo dos Negros onde habitam sujeitos que constroem "sua cidade", que fixam suas casas e espaços de pertencimento. A proposta é pensar a cidade fora de pretensões normativas.
Warhol e Duchamp: o cotidiano e o design incorporados à arte
Authors: Silva Sérgio Luciano da 
Published: December 2020

Este artigo apóia-se nas interpretações do filósofo Arthur Danto sobre as concepções de Andy Warhol e sua obra, procurando compreender como ocorre a apropriação de objetos do design por esse expoente da Pop-Art. Ao lado de Danto, o filósofo Thierry de Duve contribui para a compreensão das influências de Marcel Duchamp e do Dadaísmo, no trabalho de Warhol. O objetivo desta investigação é comprovar como a ação de Warhol promove uma mudança na significação dos objetos utilitários conduzindo-os do universo do design para o artístico. Nossa hipótese é de que a atuação desse artista, assim como a de seu antecessor, Duchamp, produz um deslocamento ontológico ao “transfigurar” objetos triviais, de uso cotidiano, em obras de arte, sem alterar suas características físicas. AbstractThis paper is based on the interpretations of the philosopher Arthur Danto on the concepts of Andy Warhol and his work, seeking to understand how the appropriation of objects of design occurs by this exponent of Pop-Art. Along with Danto, the philosopher Thierry de Duve contributes to the understanding of the influences of Marcel Duchamp and Dadaism, in Warhol’s work. The purpose of this investigation is to demonstrate how Warhol’s action promotes a change in the meaning of utilitarian objects, leading them from the universe of design to the artistic. Our hypothesis is that the artist’s performance, as well as his predecessor’s, Duchamp, produces an ontological detour by “transfiguring” trivial objects, of everyday life, into works of art, without changing their physical features.
Notas sobre a História das Exposições no discurso curatorial
Authors: Vogel Felix 
Published: December 2020

O artigo discute como a crescente importância e a transformação das exposições desde os anos 1960 têm motivado um envolvimento mais profundo com sua própria história. Nesse sentido, o autor assinala a importância dos programas de estudos curatoriais estabelecidos desde os anos 1980, uma vez que são ambientes de treinamento prático e pesquisa histórico-teórica. Contudo, argumenta que os discursos sobre as exposições ainda são quase que exclusivamente enunciados pelos próprios curadores, que a partir de seu lugar de fala se colocam ao mesmo tempo como sujeito e objeto. Assim, ao figurarem como protagonistas da História das Exposições, os curadores acabam por criar novos cânones, resultando em possível padronização e homogeneização dos modelos expositivos. AbstractThis article discusses how the growing importance and transformation of exhibitions since the 1960s have motivated a deeper involvement with their own history. In this sense, the author points out the relevance of curatorial study programs established since the 1980s, once they are environments for practical training and historical-theoretical research. However, he argues that discourses about exhibitions are still almost exclusively enunciated by curators themselves, who, from their speaker position, place themselves at the same time as subject and object. Thus, by appearing as protagonists in the History of Exhibitions, curators end up creating new canons, resulting in possible standardization and homogenization of exhibition models
Em quarentena: apontamentos sobre educação em museus em tempos de pandemia
Authors: Schenkel Camila 
Published: December 2020

O presente artigo reflete sobre os desafios impostos à área de educação em museus durante a pandemia de Covid-19 a partir de três eixos: uma análise de estratégias adotadas por grandes instituições culturais durante o isolamento; a fragilidade das equipes educativas dentro dessas instituições; e as dificuldades de transpor os fundamentos da mediação para o ambiente digital. Recorrendo a pesquisas de Carmen Mörsch sobre mediação e reflexões recentes de Jacques Rancière e Franco Berardi, entre outras referências, destaca-se a importância do conhecimento prático acumulado pelas equipes educativas para desenvolver formas menos excludentes e hierarquizadas de relações com obras e públicos. AbstractThis article considers de challenges faced by museum education during the Covid-19 pandemics from three points: an analysis of the strategies adopted by mainstream cultural institutions during quarantine; the fragile position of educating teams inside these institutions and the obstacles to transpose the characteristics of mediation to digital platforms. Based on Carmen Mörsch’s research on cultural mediation and recent writings of Jacques Rancière and Franco Berardi, among other references, the practical knowledge acquired by education teams is pointed out as a valuable resource in order to develop less excluding and hierarchical relations with works and publics.
Estratégias abdutivas no processo de criação artística
Authors: Rocha Luiz Antonio Carvalho da 
Published: December 2020

O texto é um processo reflexivo sobre meu fazer artístico, das formas de operar as trajetórias e percursos no andamento da produção artística e das caraterísticas que considero relevantes para a atual produção. O texto aborda também a ação na matéria, o fazer, buscando estratégias abdutivas na construção de sentido e, a partir daí, as diferentes possibilidades geradas pelos cruzamentos e convergências constituídos na operação com a matéria, enfocando a maneira de buscar internamente uma condição reflexiva e analítica dos fluxos mentais, estabelecendo a hegemonia do raciocínio visual para o processo decisório na construção do trabalho AbstractThe text is a reflective process about my artistic making, the ways of operating the trajectories and paths in the course of the artistic production and the characteristics I consider relevant to my current production. The text also addresses the action in matter, the doing, searching abductive strategies in the construction of meaning and, from this, the different possibilities generated by the intersections and convergences constituted in the operation on the matter, mainly searching internally a reflective and analytical condition of mental flows, establishing the hegemony of visual reasoning for the decision-making process in the construction of my work.
Da fotografia como circum-navegação da antropologia
Authors: Sterzi Eduardo 
Published: December 2020

“Eu fotografo, mas não sou fotógrafo [...]”. “Eu [...] vejo a fotografia como um modo de fugir da antropologia, de sair da antropologia, assim como vi na antropologia indígena que eu escolhi como profissão um modo de sair do Brasil.” Jamais foram simples – por mais que tenham sido constantes – as relações entre antropologia e fotografia no percurso intelectual de Eduardo Viveiros de Castro. Durante muito tempo, até recentemente, era perceptível certo desconforto do antropólogo quando convidado a discorrer sobre suas experiências fotográficas. Esse desconforto vinha talvez de não saber indicar exatamente qual o lugar que a fotografia ocupava em meio a uma prática antropológica sempre mais consolidada e reconhecida. É essa própria persistência da fotografia a despeito do desconforto que, porém, merece ser pensada. Abstract“I do take photographs, but I am not a photographer [...]”. “I [...] see photography as a way of escaping from anthropology, leaving anthropology, just as I saw in indigenous anthropology, which I chose as a profession, as a way of getting away from Brazil.” Relations between anthropology and photography—however constant—have never been straightforward in Eduardo Viveiros de Castro’s intellectual development. For a long time, indeed until quite recently, he clearly evinced discomfort or hesitancy when asked to discuss his photographic experiences—perhaps due to an inability to pinpoint photography’s role in his increasingly consolidated and recognized anthropological practice. However, it is this very persistence of his photography—despite his discomfort—that ought to be examined.
Conversion of heavy gasoil into ultra-low sulfur and aromatic diesel over NiWRu/TiO2–γAl2O3catalysts: Role of titanium and ruthenium on improving catalytic activity
Authors: Prada Silvy Ricardo , Lageshetty Sathish Kumar 
Published: December 2020

This contribution deals with about selective conversion of heavy gas oils into middle distillates fuels that meet ultra-low sulfur and aromatic compound quality standards by using a novel NiWRu/TiO2–γAl2O3catalyst under typical hydrotreatment conditions. A diesel fuel fraction having sulfur, nitrogen and aromatics compound content of about 50 ppm, 10 ppm and 15 v%, respectively, was obtained when the reactor was operated atT = 370 °C,P = 12.4 MPa, LHSV = 0.5 h−1and H2/hydrocarbon ratio = 800 Nm3/m3. Titanium and ruthenium additives used in the preparation of the NiWRu/TiO2–γAl2O3catalyst, remarkably improved the catalytic activities for the hydrogenolysis, hydrogenation and hydrocracking reactions compared to the reference NiW/γAl2O3catalyst. The coprecipitation of titanium and aluminum hydroxides produced a catalyst support having greater surface area, pore volume and surface acidity. An improvement in mechanical properties of the support extrudates was also observed. Characterization analysis by XPS, AUGER and XRD techniques of the TiO2–γAl2O3support suggested the formation of an aluminum-titanate mixed phase (AlxTiyOz) having a non-well-defined stoichiometry. The NiW/TiO2–γAl2O3and NiWRu/TiO2–γAl2O3exhibited a greater surface dispersion of the supported nickel and tungsten species compared to the NiW/γAl2O3catalyst. The promoter effect of ruthenium on the NiW bimetallic system caused a strong increase in both hydrogenolysis and hydrogenation reactions. Hydrodenitrogenation and hydrocracking reactions were also favored by the increase in the hydrogenation capacity and in the surface acidity of the catalyst. The highest conversion levels for all investigated reactions were obtained when the NiWRu/TiO2–γAl2O3catalyst was prepared by co-impregnation of Ni and Ru in a second step. This catalyst showed sulfur tolerance properties when the reaction was conducted in the presence of different H2S partial pressures. The catalytic behavior of the NiWRu/TiO2–γAl2O3catalyst was explained by the existence of a promoting effect between separated Ni and Ru sulfides species and the NiWS phase (dual mechanism).
Dissolving Pulp dari Kayu dan Nonkayu: Tinjauan Proses Pembuatan dan Karakteristiknya
Authors: Biantoro Reynaldo , Septiningrum Krisna , Kardiansyah Teddy 
Published: December 2020

Pemanfaatan derivat selulosa menjadi viskosa rayon saat ini berkembang secara signifikan; dalam hal ini pulp khusus yang digunakan adalah dissolving pulp. Dissolving pulp ini memiliki karakteristik tertentu seperti kandungan selulosa tinggi (> 90%), kadar hemiselulosa rendah, lignin dan kandungan ekstraktif (kurang dari 10%), reaktivitas selulosa tinggi dengan tingkat distribusi berat molekul dan kecerahan tinggi, serta memiliki viskositas sekitar 200-300 dm3/kg. Saat ini, pembuatan dissolving pulp diarahkan untuk penggunaan bahan baku kayu dan non-kayu yang melimpah dengan menggunakan metode ramah lingkungan. Secara umum terdapat empat metode utama termasuk teknologi konvensional dan terbaru yang dapat digunakan untuk membuat dissolving pulp seperti: 1. Metode bisulfit menggunakan gas SO2 dengan yield sekitar 55 -75%; 2. Metode sulfit-soda yang mampu menghasilkan kandungan selulosa yang tinggi (hingga 96%); 3. Pra-hidrolisis kraft yang merupakan metode populer dalam pembuatan dissolving pulp dan 4. Konversi pulp kertas menjadi dissolving pulp. Dalam makalah ini dibahas pembuatan dissolving pulp menggunakan enzim seperti xilanase dan mono komponen endoglukanase dan kombinasi antara mekanik, kimia dan metode enzimatik. Kata kunci: dissolving pulp, pra-hidrolisis kraft, enzim, konversi pulp kertas
Structural Determinants for the Mode of Action of the Imidazopyridine DS2 at d-containing g-Aminobutyric Acid Type A (GABAA) Receptors
Authors: Frølund Bente , Rostrup Frederik , Falk-Petersen Christina Birkedahl , Harpsøe Kasper , Buchleithner Stine , Conforti Irene , Jung Sascha , Gloriam David E. , Schirmeister Tanja , Wellendorph Petrine 
Published: December 2020

A SAR study of the delta-selective positive modulators DS2 was performed to assist the quest for the binding site. The modulatory effect was measured using a fluorometric inaging plate reader (FLIPR) membrane potential (FMP) functional assay. Specific positions in the structural scaffold of DS2 was found to severly affect the pharmacological profile. Analogs superior to DS2 were identified displaying higher potency and selectivity for the alfa4beta1delta over alfa4beta1gamma.
Legitimidade de acesso à reprodução assistida post mortem (RAPM)
Authors: Ribeiro Raphael Rego Borges 
Published: December 2020

Neste artigo, investigamos quem é legitimado para proceder à reprodução assistida post mortem. Questionamos se apenas o cônjuge ou companheiro(a) supérstite pode utilizar os gametas criopreservados. Procedemos a consulta bibliográfica e normativa, usando o método dedutivo. Observamos que o elemento fundamental para o acesso à RAPM é o consentimento do(a) falecido(a). Concluímos que a legitimidade para a RAPM independe: (a) do estado civil de quem congelou material genético; (b) do estado civil de quem quer acesso póstumo ao material germinativo; (c) de ter havido vínculo de casamento ou união estável entre o(a) morto(a) e quem quer usar os gametas criopreservados.
Effectiveness of Sexual Harassment Risk Reduction Education based on Health Belief Model: A Quasi Experimental Study
Authors: Thapaliya Radhika , Adhikari Samir Kumar 
Published: December 2020

Background: Sexual harassment is a public health problem which has serious effects to girls’ psychosomatic health. Due to social stigma and lack of skills, even the girls can’t refuse sexual harassment. This study was done to evaluate the effectiveness of sexual harassment risk reduction education based on Health Belief Model.
Methods: A quasi experimental study was conducted in secondary level public schools of Tokha Municipality, Kathmandu. The study was done from 5th February 2016 to 5th May 2016. The sample size was 117 for each group which was calculated with input of 95% CI, power of test=80%, assuming 38 % change based on baseline study and 10% nonresponse rate. The ratio of participants in intervention and control group was 1:1 and the total numbers of participants were 128 in pretest and 121 in posttest at the intervention group and 131 in pretest and 122 in posttest in the control group. Data was collected by using self-administered questionnaire for knowledge and likert’s scale was used for attitude and behavioural intention. Lecture, group discussion, role play and brainstorming were methods used for intervention. After two weeks of intervention, a post-test was done.
Results: Testing of hypothesis revealed that the knowledge about sexual harassment, anti-sexual harassment attitude and behavioural intention of using refusal skills in sexual harassment in the intervention group were significantly higher than that of control groups i.e. p<0.001, p<0.001 and p<0.05 respectively.
Conclusion: Sexual harassment risk reduction education intervention based on health belief model is effective to increase the knowledge, attitude and behavioural intention of participants. The findings of the study encourage further exploring creative approaches to programming in other violence prevention areas.
Impact of specialized multidisciplinary care on cirrhosis outcomes and acute care utilization
Authors: Carbonneau Michelle , Davyduke Tracy , Congly Stephen E , Ma Mang M , Newnham Kim , Den Heyer Vanessa , Tandon Puneeta , Abraldes Juan G 
Published: December 2020

Background: Multidisciplinary care has the potential to improve outcomes among patients with cirrhosis, yet its impact on this population remains unclear, with existing studies demonstrating discrepant results. Using data from the multidisciplinary outpatient Cirrhosis Care Clinic (CCC) at the University of Alberta Hospital, we aimed to evaluate acute care utilization and survival outcomes of patients followed by the CCC compared with those receiving standard care (SC). Methods: We performed a retrospective chart review of 212 patients with cirrhosis admitted to University of Alberta Hospital between 2014 and 2015. CCC patients ( n = 36) were followed through the CCC before index admission. SC patients ( n = 176) were managed outside of the CCC. Readmission time in hospital was collected until 1 year, death, or liver transplant. Results: CCC patients had more advanced liver disease (higher prevalence of ascites, encephalopathy, and varices). Despite this, acute care utilization was significantly lower among CCC patients (adjusted length of stay lower by 3 days, p = 0.03, and adjusted survival days spent in hospital lower by 9%, p = 0.02). CCC patients also had improved 1-year transplant-free survival, with an adjusted 1-year relative risk reduction of 53% ( p = 0.03). Total mean cost of care was lower in the CCC group by $2,280 per patient-month of life. Discussion: For patients admitted with cirrhosis, specialized post-discharge multidisciplinary outpatient care is associated with decreased acute care utilization, improved 1-year transplant-free survival probability, and the potential for cost savings to the system.
Effects of Astragalus Polysaccharides Nanoparticles on Cerebral Thrombosis in SD Rats
Authors: Sun Qian , Shi Pengqiang , Lin Cuiling , Ma Jing 
Published: December 2020

ObjectiveTo investigate the efficacy and improvement of Astragalus polysaccharides (APS) and APS-nano on cerebral thrombosis in rats.MethodsA total of 72 SD rats were randomly divided into NC group, Model group, APS-Nano group, and APS group. The cerebral thrombosis Model of SD rats was established by injecting compound thrombus inducer into the internal carotid artery. After 14 days of different intervention treatments, the TTC staining of brain tissue were performed, and A/left brain wet weight ratio, left brain/right brain wet weight ratio, blood rheology indexes, and coagulation function indexes of cerebral thrombosis were measured. ELISA was used to measure the contents of thromboxane 2 (TXB2), 6-keto-prostaglandin F1α (6-Keto-PGF1α), tissue factor (TF), neuron-specific enolase (NSE), S-100β, catenin (CAT), superoxide dismutase (SOD), as well as malondialdehyde (MDA). The binding specificity between miR-885-3p and TF was verified by the double-luciferin reporting experiment, and western blot was used to measure the expression level of TF protein.ResultsCompared with the Model group, after treatment with APS-nano or APS, the ratio of left brain/right brain wet weight decreased significantly. Whole blood low shear viscosity (WBLSV), whole blood high shear viscosity (WBHSV), plasma viscosity (PV), and erythrocyte aggregation index (Arbc) was all reduced. In addition, prothrombin time (PT) and activated partial thromboplastin time (APTT) were increased, and fibrinogen (FIB) content was decreased. The expression of TXB2, 6-Keto-PGF1α, and TF showed a downward trend. Similarly, the expression of TF protein was decreased. Furthermore, the contents of NSE and S-100β proteins were all decreased, whereas the contents of CAT and SOD were increased, and the contents of MDA was decreased. At the same dose, compared with APS treatment, APS-nano treatment had a significant inhibitory effect on cerebral thrombosis in rats. Finally, we found that TF is a target gene of miR-885-3p and specifically binds to miR-885-3p.ConclusionAPS has a significant inhibitory effect on the formation of cerebral thrombosis induced by compound thrombus inducers. Moreover, APS-nano has a more significant inhibitory effect on cerebral thrombosis. Meanwhile, the regulation of miR-885-3p regulating TF expression may be related to the occurrence of cerebral thrombosis.
Human Short Peptidoglycan Recognition Protein PGLYRP1/Tag-7/PGRP-S Inhibits Listeria monocytogenes Intracellular Survival in Macrophages
Authors: Slonova Darya , Posvyatenko Alexandra , Kibardin Alexey , Sysolyatina Elena , Lyssuk Elena , Ermolaeva Svetlana , Obydennyi Sergei , Gnuchev Nikolay , Georgiev Georgii , Severinov Konstantin , Larin Sergey 
Published: December 2020

PGLYRP1/Tag-7/PGRP-S is one of mammalian peptidoglycan recognition proteins (PGRPs). Here, we demonstrate that human recombinant PGLYRP1/Tag-7/PGRP-S potentiates the response of murine macrophage-like ANA-1 cells and human macrophages to facultative intracellular pathogen Listeria monocytogenes. PGLYRP1/Tag-7/PGRP-S binds to the surface of L. monocytogenes and other bacterial cells but has no effect on their growth in culture. While PGLYRP1/Tag-7/PGRP-S treatment modestly enhanced phagocytosis of bacteria by ANA-1 cells, the intracellular survival of PGLYRP1/Tag-7/PGRP-S treated L. monocytogenes was strongly inhibited 2 h after internalization. PGLYRP1/Tag-7/PGRP-S treatment of bacteria boosted oxidative burst induction and increased the level of proinflammatory cytokine IL-6 produced by ANA-1, however, these effects happened too late to be responsible for decreased intracellular survival of bacteria. Our results thus suggest that PGLYRP1/Tag-7/PGRP-S acts as a molecular sensor for detection of L. monocytogenes infection of mammalian cells that leads to increased killing through a mechanism(s) that remains to be defined.