bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating fashion retailers' intellectual capital: key money as a part of customer capital
Authors: Fiano Fabio , Mueller Jens , Paoloni Niccolò , Farina Briamonte Massimiliano , Magni Domitilla 
Published: July 2020

PurposeThe purpose of this paper is to enrich the scientific and managerial debate on intangibles by placing the concept of key money within the broader concept of Intellectual Capital, and by proposing an evaluation approach for a portion of the latter, focusing the analysis on fashion retailers.Design/methodology/approachThis research focuses on the fashion industry, given that key money gains particular significance and accounted for in fashion retailers' financial statements. A comparative case study is presented with regard to the application of two evaluation methods proposed to some fashion retailers operating in Italy.FindingsThis paper defines a suitable placement for key money within the vast structure of intellectual capital. The research shows that the two methods give “very close” key money values, thus laying the foundations for a theoretical articulation of interest to be further explored in future researches.Originality/valueThe document represents a first in-depth examination regarding the evaluation and inclusion of key money in the intellectual capital. A further element of originality lies in having interpreted the key money in a perspective closer to the world of intangibles and competitive strategies, to the detriment of the previous (meagre) settings that placed it within the real estate branches of study.
Parents' burdens of service for children with ASD – implications for service providers
Authors: Helkkula Anu , Buoye Alexander John , Choi Hyeyoon , Lee Min Kyung , Liu Stephanie Q. , Keiningham Timothy Lee 
Published: July 2020

PurposeThe purpose of this investigation is to gain insight into parents' perceptions of benefits vs burdens (value) of educational and healthcare service received for their child with ASD. Parents are the main integrators of long-term educational and healthcare service for their child with ASD.Design/methodology/approachDesign/methodology/approach included (1) a sentiment analysis of discussion forum posts from an autism message board using a rule-based sentiment analysis tool that is specifically attuned to sentiments expressed in social media and (2) a qualitative content analysis of one-on-one interviews with parents of children diagnosed with ASD, complemented with interviews with experienced educators and clinicians.FindingsFindings reveal the link between customized service integration and long-term benefits. Both parents and service providers emphasize the need to integrate healthcare and educational service to create holistic long-term care for a child with ASD. Parents highlight the benefits of varied services, but availability or cost are burdens if the service is not publicly provided, or covered by insurance. Service providers' lack of experience with ASD and people's ignorance of the challenges of ASD are burdens.Practical implicationsEnsuring health outcomes for a child with ASD requires an integrated service system and long-term, customer-centric service process because the scope of service covers the child's entire childhood. Customized educational and healthcare service must be allocated and budgeted early in order to reach the goal of a satisfactory service output for each child.Originality/valueThis is the first service research to focus on parents' challenges with obtaining services for their child with ASD. This paper provides service researchers and managers insight into parents' perceptions of educational and healthcare service value (i.e. benefits vs. burdens) received for their child with ASD. These insights into customer-centric perceptions of value may be useful to research and may help service providers to innovate and provide integrated service directly to parents, or indirectly to service providers, who serve children with ASD.
COVID-19 – school leadership in crisis?
Authors: Harris Alma 
Published: July 2020

PurposeThis article explores how school leaders are responding during COVID-19 and what forms of leadership practice are emerging.Design/methodology/approachThis article draws upon the contemporary leadership literature and scholarly work.FindingsThis article proposes that the current crisis has shifted school leadership dramatically towards distributed, collaborative and network practices.Originality/valueThis article offers a commentary about the changing role of school leaders and their changing leadership practice during this pandemic.
Quality assurance dimensions for e-learning institutions in Gulf countries
Authors: Anwar Syed Aziz , Sohail M. Sadiq , Al-Marri Meera 
Published: July 2020

Purpose
It has been argued in the literature that quality assurance is a relative concept. In view of the new challenges (and opportunities) created by e-learning institutions in the Gulf Cooperation Council (GCC) countries, this paper aims to explore the dimensions of quality assurance in e-learning and test the psychometric properties of the underlying dimensions.

Design/methodology/approach
A sequential mixed methods approach was applied in this study. In the qualitative phase, items were generated using the inductive and deductive approaches. This was then followed by the quantitative phase where data was collected from 275 senior academics, scholars and administrators associated with e-learning institutions in Kuwait, UAE and Saudi Arabia.

Findings
The findings of this study revealed that e-learning quality assurance is a multidimensional construct. The dimensions of accreditation, assessment, accountability and benchmarking were identified. Further, the model demonstrated adequacy in its validity and reliability.

Practical implications
In the light of proliferation of e-learning courses in GCC countries, the results of this are invaluable to enable administrators and instructors to design strategy and foster innovation in the domain of quality assurance. E-learning institutions operating in a competitive environment have to design and implement an effective strategy to achieve innovation, uniqueness and diversity in the educational sector of their countries.

Originality/value
This paper has successfully validated an e-learning quality assurance questionnaire, which can be used effectively for evaluating e-learning programmes.
Do lump-sum investing strategies really outperform dollar-cost averaging strategies?
Authors: Lu Richard , Hoang Vu Tran , Wong Wing-Keung 
Published: July 2020

PurposeThe literature has demonstrated that lump-sum (LS) outperforms dollar-cost averaging (DCA) in uptrend markets while DCA outperforms LS only when the asset price is mean-reverted or downtrend. To bridge the gap in the literature, this study aims to use both Sharpe ratio (SR) and economic performance measure (EPM) to compare the performance of DCA and LS under both accumulative and disaccumulative approaches when the asset price is simulated to be uptrend.Design/methodology/approachThis study uses both disaccumulative and accumulative approaches to compare DCA with LS and uses both SR and EPM to evaluate their performance when the asset price is simulated to be uptrend. Instead of using the annualized returns that are commonly used by other DCA studies, we compute the holding-period returns in the comparison in this paper.FindingsThe simulation shows that no matter which approach is used, DCA outperforms LS in nearly all the cases in the less uptrend markets while DCA still performs better than LS in many cases of the uptrend markets, especially when the market is more volatile and investment horizon is long, regardless which approach the authors used. The authors also find more evidence supporting DCA over LS by using EPM, which is more suitable in the analysis because the returns generated by DCA are positive skewed and flat-tailed that are ignored when SR is used.Research limitations/implicationsThe authors conclude that DCA is a better trading strategy than LS for investment even in the uptrend market, especially on high risky assets.Practical implicationsInvestors could consider choosing DCA instead of LS as their trading strategy, especially when they prefer long term investment and investing in high-risk assets.Social implicationsFund managers could consider recommending DCA to their customers, especially when they prefer long term investment and investing in high-risk assets.Originality/valueThis is the own study and, as far as the authors know, this is the first study in the literature uses both SR and EPM to compare the performance of DCA and LS under both accumulative and disaccumulative approaches when the asset price is simulated to be uptrend.
Benefits at the nanoscale: a review of nanoparticle‐enabled processes favouring microbial growth and functionality
Authors: Mansor Muammar , Xu Jie 
Published: July 2020

SummaryNanoparticles are ubiquitous and co‐occur with microbial life in every environment on Earth. Interactions between microbes and nanoparticles impact the biogeochemical cycles via accelerating various reaction rates and enabling biological processes at the smallest scales. Distinct from microbe‐mineral interactions at large, microbe‐nanoparticle interactions may involve higher levels of active recognition and utilization of the reactive, changeable, and thereby 'moldable' nano‐sized inorganic phases by microbes, which has been given minimal attention in previous reviews. Here we have compiled the various cases of microbe‐nanoparticle interactions with clear and potential benefits to the microbial cells and communities. Specifically, we discussed (i) the high bioavailabilities of nanoparticles due to increased specific surface areas and size‐dependent solubility, with a focus on environmentally‐relevant iron(III) (oxyhydr)oxides and pyrite, (ii) microbial utilization of nanoparticles as 'nano‐tools' for electron transfer, chemotaxis, and storage units, and (iii) speculated benefits of precipitating 'moldable' nanoparticles in extracellular biomineralization. We further discussed emergent questions concerning cellular level responses to nanoparticle‐associated cues, and the factors that affect nanoparticles' bioavailabilities beyond size‐dependent effects. We end the review by proposing a framework towards more quantitative approaches and by highlighting promising techniques to guide future research in this exciting field.
Is there a connection between immunohistochemical markers and grading of lung cancer with apparent diffusion coefficient (ADC) and standardised uptake values (SUV) of hybrid 18F‐FDG‐PET/MRI?
Authors: Martin Ole , Bruckmann Nils‐Martin , Kirchner Julian , Ullrich Tim , Ingenwerth Marc , Bogner Simon , Eze Chukwuka , Nensa Felix , Herrmann Ken , Umutlu Lale , Antoch Gerald , Sawicki Lino M 
Published: July 2020

AbstractIntroductionTo correlate tumour grading and prognostic immunohistochemical markers of lung cancer with simultaneously acquired standardised uptake values (SUV) and apparent diffusion coefficient (ADC) derived from hybrid PET/MRI.MethodsIn this retrospective study, 55 consecutive patients (mean age 62.5 ± 9.2 years) with therapy‐naïve, histologically proven lung cancer were included. All patients underwent whole‐body PET/MRI using 18F‐flourdeoxyglucose (18F‐FDG) as a radiotracer. Diffusion‐weighted imaging of the chest (DWI, b‐values: 0, 500, 1000 s/mm2) was performed simultaneously with PET acquisition. Histopathological tumour grading was available in 43/55 patients. In 15/55 patients, immunohistochemical markers, that is, phospho‐AKT Ser473 (pAKTS473), phosphorylated extracellular signal‐regulated kinase (pERK), phosphatase and tensin homolog (PTEN), and human epidermal growth factor receptor 2 (erbB2) were available.ResultsThe average SUVmax, SUVmean, ADCmin and ADCmean in lung cancer primaries were 12.6 ± 5.9, 7.7 ± 4.6, 569.9 ± 96.1 s/mm2 and 825.8 ± 93.2 s/mm2, respectively. We found a significant inverse correlation between the ADCmin and SUVmax (r = −0.58, P < 0.001) as well as between the ADCmin and SUVmean (r = −0.44, P < 0.001). Tumour grading showed a significant positive correlation with SUVmax and SUVmean (R = 0.34 and R = 0.31, both P < 0.05) and a significant inverse correlation with ADCmin and ADCmean (r = −0.30 and r = −0.40, both P < 0.05). In addition, erbB2 showed a significant inverse correlation with SUVmax and SUVmean (r = −0.50 and r = −0.49, both P < 0.05). The other immunohistochemical markers did not show any significant correlation.Conclusion18F‐FDG‐PET/MRI showed weak to moderate correlations between SUV, ADC, tumour grading and erbB2‐expression of lung cancer. Hence, 18F‐FDG‐PET/MRI may, to some extent, offer complementary information to the histopathology of lung cancer, for the evaluation of tumour aggressiveness and treatment response.
Prediction of tumor doubling time of lung adenocarcinoma using radiomic margin characteristics
Authors: Yoon Hyun Jung , Park Hyunjin , Lee Ho Yun , Sohn Insuk , Ahn Joonghyun , Lee Seung‐Hak 
Published: July 2020

AbstractBackgroundBecause shape or irregularity along the tumor perimeter can result from interactions between the tumor and the surrounding parenchyma, there could be a difference in tumor growth rate according to tumor margin or shape. However, no attempt has been made to evaluate the correlation between margin or shape features and tumor growth.MethodsWe evaluated 52 lung adenocarcinoma (ADC) patients who had at least two computed tomographic (CT) examinations before curative resection. Volume‐based doubling times (DTs) were calculated based on CT scans, and patients were divided into two groups according to the growth pattern (GP) of their ADCs (gradually growing tumors [GP I] vs. growing tumors with a temporary decrease in DT [GP II]). CT radiomic features reflecting margin characteristics were extracted, and radiomic features reflective of tumor DT were selected.ResultsAmong the 52 patients, 41 (78.8%) were assigned to GP I and 11 (21.2%) to GP II. Of the 94 radiomic features extracted, eccentricity, surface‐to‐volume ratio, LoG uniformity (σ = 3.5), and LoG skewness (σ = 0.5) were ultimately selected for tumor DT prediction. Selected radiomic features in GP I were surface‐to‐volume ratio, contrast, LoG uniformity (σ = 3.5), and LoG skewness (σ = 0.5), similar to those for total subjects, whereas the radiomic features in GP II were solidity, energy, and busyness.ConclusionsThis study demonstrated the potential of margin‐related radiomic features to predict tumor DT in lung ADCs.Key pointsSignificant findings of the studyWe found a relationship between margin‐related radiomic features and tumor doubling time.What this study addsMargin‐related radiomic features can potentially be used as noninvasive biomarkers to predict tumor doubling time in lung adenocarcinoma and inform treatment strategies.
Incidence and Prediction of Unstable Blood Glucose Level among Critically Ill Patients: A Cohort Study
Authors: Brinati Lídia Miranda , de Fátima Januário Carla , Balbino Paula Coelho , Gonçalves Rezende Macieira Tamara , Cardoso Silvia Almeida , Moreira Tiago Ricardo , de Oliveira Salgado Patrícia 
Published: July 2020

PURPOSETo evaluate the incidence and the prediction of unstable blood glucose level among critically ill patients hospitalized in an intensive care unit.METHODSA cohort study was conducted with 62 adult patients hospitalized at an intensive care unit of a hospital located in Minas Gerais, Brazil, between March and July of 2017. Patient's demographic information, along with scores for Simplified Acute Physiology Score III, primary medical diagnosis, discharge status, diagnosis of diabetes and/or sepsis, length of stay, glycemic variability, type of nutrition, types of medications and treatments, and oxygen therapy were collected daily. A daily venous blood sample was collected to measure blood glucose levels during the patient's hospitalization period. Bivariate analysis was used to explore the association among the potential diagnostic indicators and the outcome of unstable blood glucose levels. Multivariate Cox regression was used to identify the potential predictors for the outcome.FINDINGSOf the total of 62 participants, 45.1% (n=28) had unstable blood glucose level. Among the 28 patients with unstable blood glucose levels, half of them (n=14, 50%) had hypoglycemia and the other half had hyperglycemia (n=14, 50%). Decreased number of days hospitalized and the use of intensive glucose control with regular insulin were associated with decreased odds of developing hyperglycemia. The presence of mechanical ventilation was associated with a higher risk for the development of hypoglycemia.CONCLUSIONSThis study provides knowledge and evidence of diagnostic indicators for unstable blood glucose levels that are not currently included in the NANDA‐International terminology for the nursing diagnosis Risk for unstable blood glucose level (00179).IMPLICATIONS FOR NURSING PRACTICEThis study identified important diagnostic indicators that nurses can observe during the assessment to identify patients that are at risk for developing unstable blood glucose level and provide the appropriate care.
Integrative transcriptome analysis deciphers mechanisms of nickel contact dermatitis
Authors: Wisgrill Lukas , Werner Paulina , Jalonen Erja , Berger Angelika , Lauerma Antti , Alenius Harri , Fyhrquist Nanna 
Published: July 2020

AbstractBackgroundNickel‐induced allergic contact dermatitis (nACD) remains a major occupational skin disorder, significantly impacting the quality of life of suffering patients. Complex cellular compositional changes and associated immunological pathways are partly resolved in humans; thus, the impact of nACD on human skin needs to be further elucidated.MethodsTo decipher involved immunological players and pathways, human skin biopsies were taken at 0, 2, 48, and 96 hours after nickel patch test in six nickel‐allergic patients. Gene expression profiles were analyzed via microarray.ResultsLeukocyte deconvolution of nACD‐affected skin identified major leukocyte compositional changes at 48 and 96 hours, including natural killer (NK) cells, macrophage polarization, and T‐cell immunity. Gene set enrichment analysis mirrored cellular‐linked functional pathways enriched over time. NK cell infiltration and cytotoxic pathways were uniquely found in nACD‐affected skin compared to sodium lauryl sulfate–induced irritant skin reactions.ConclusionThese results highlight key immunological leukocyte subsets as well as associated pathways in nACD, providing insights into pathophysiology with the potential to unravel novel therapeutic targets.
Supervised shift k‐means based machine learning approach for link prediction using inherent structural properties of large online social network
Authors: Bhanodia Praveen Kumar , Khamparia Aditya , Pandey Babita 
Published: July 2020

AbstractSocial network analysis can be used to address the challenges of link prediction in a social network through the measuring and processing of the inherent structural properties of the network. By developing relationships between the anonymous types on networks such as Facebook and Twitter, social network analysis can determine the prediction of future and missing links among the nodes, as well as assist in developing a predictive system. Various techniques have been discussed with proposals for network link prediction methodologies. The scaling of social networks, differences in local and global features, and efficient and precise prediction of links are issues for further study. We propose a collaborative model for link prediction that offers the benefit of structural‐based and machine learning techniques. The model produces meaningful results for the prediction of strong and weak links. In this study, we consider node‐based feature parameters for the clustering of the social network.
How does chronic obstructive pulmonary disease affect the survival of patients with stage 4 lung cancer?
Authors: Cireli Emel , Balcı Günseli , Mertoğlu Aydan 
Published: July 2020

AbstractBackgroundLung cancer risk is increased in COPD. However, it is not clear how COPD affects the course of lung cancer.AimTo determine whether the overall survival of stage 4 lung cancer patients differ in various COPD stages. Study design: A cross‐sectional retrospective study.MethodsWe screened lung cancer patients with ICD code: C34 and included stage 4 lung cancer patients with histological diagnosis and pulmonary function tests at admission in the study. Demographic data, stages, metastasis sites and number of metastases, performance status, pulmonary function tests, Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages, arterial blood gasses and treatment methods were recorded on a standardised database. We checked their dates of death from national database. Data were evaluated with SPSS programme version 18. Results: Out of 900 patients, 146 patients had stage 4 disease at the time of diagnosis and, 127 patients had COPD. There was a significant difference between survivals of stage 4 cancer patients with different COPD stages. As COPD stage increased, overall survival worsened (P = 0.037). Factors affecting survival were bone metastasis (P = 0.01, OR = 1.72), liver metastasis (P = 0.04, OR = 1.87), brain metastasis (P = 0.001, OR = 2.6), having N 2‐3 disease (P = 0.01, OR = 1.79) and GOLD 4 COPD (P = 0.01, OR = 2.28).ConclusionAs COPD becomes more severe, overall survival rates of stage 4 patients worsen. Bone metastasis, liver metastasis, brain metastasis, having N2‐3 disease and GOLD 4 COPD worsen the overall survival.
The role of breast fine needle aspiration during and post‐COVID‐19 pandemic: A fast and safe alternative to needle core biopsy
Authors: Pinto Daniel , Schmitt Fernando 
Published: July 2020

AbstractFine needle aspiration (FNA) may be used to study breast lesions in patients that do not have access to more complex procedures during the COVID‐19 pandemic. Furthermore, FNA can be a helpful screening method in the post‐pandemic era when a greater number of patients than usual with delayed treatment can overburden clinics and hospitals.
Facilitating personal development for public involvement in health‐care education and research: A co‐produced pilot study in one UK higher education institute
Authors: Read Sue , Aries Alison M. , Ashby Sue M. , Bambrick Val , Blackburn Steven J. , Clifford Helen , Rhodes Carol , Thirlwall Sarah , Watkins Carole A. 
Published: July 2020

AbstractBackgroundPublic involvement in the education of students enrolled on higher education programmes has gained impetus. For students enrolled on professional health‐care programmes and health‐related modules in the UK, there is also a requirement by professional bodies to include “service user” involvement in preparation for entry to a professional health‐care register and continuing professional development. Actively involving patients and members of the public in research is also a requirement by many research funders. In this article, the term Patient and Public Involvement (PPI) will be used throughout to include lay members, volunteers, user and carers.ObjectivesA unique pilot study was introduced across a health faculty to integrate PPI in a deliberate way. It aimed to provide an educational, focused programme of events that was meaningful to develop and inform peoples’ knowledge, skills and confidence for their involvement in the health faculty.DesignPPI members volunteered to sit on a steering group to determine the educational journey; the outcomes of three focus groups with PPI members (N = 32) and academics informed the programme content which included a range of workshops covering the exploration of public roles and barriers to involvement, introduction to research and interviewing skills.ResultsThe workshops were well attended, and outcomes indicated the importance of co‐production when designing, delivering and evaluating programmes.DiscussionCo‐production underpinned this pilot study, resulting in a programme which was meaningfully received by public contributors.RecommendationsCo‐production was seen as integral to this research to ensure that outcomes were indeed “fit for purpose”.