bluuebunny/crossref_metadata_2025_split huggingface dataset:
Withdrawal Notice: Burden of Thyroid Dysfunction on Type 2 Diabetes Mellitus Patients with Emphasis on its Prevalence and Pattern of Presentation: A Case Controlled Study
Authors: Ezeani Ignatius , Ogbonna SU 
Published: February 2020

The article has been withdrawn at the request of the editor of the journal Current Diabetes Reviews.

Bentham Science apologizes to the readers of the journal for any inconvenience this may caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham Science Disclaimer:
It is a condition of publication that manuscripts submitted to this journal have not been published and will not be
simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been
published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is
strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal
right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By
submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and
when the article is accepted for publication.
Socioeconomic Consequences of Cervical Cancer: A Narrative Review
Authors: Refaei Mansoureh , Aghababaei Soodabeh , Yazdkhasti Mansoureh 
Published: February 2020

Background:
Cervical cancer affects women in the time that they are critical to economic
and social stability.

Objective:
The aim of this narrative review to assess the socio-economic consequences of cervical
cancer.

Methods:
In this review, Pubmed, Scopus, ISI web of science, Conferences databases and Iranian
databases were searched. In order to search related articles, researchers used the following terms:
“Uterine cervical neoplasms” OR ‘cervical cancer”; Costs and cost analysis; costs of illness, burden,
socioeconomic. After the primary search, some records were obtained from 1960 to 2018. After
studying titles, abstracts, and in some cases the full texts, 48 relevant articles were included in
this research.

Results:
Hospitalization costs were the highest direct costs. However, total social costs are higher
than health and medical costs. There is a dramatic increase in direct costs with the increase in age
and stage of the disease. The costs are less for people aged 75 and up and for stage 4 because of less
invasive treatment received by older women and the limited choice of treatment in advanced stages.
The costs for persons who were screened 6 months to 5 years before diagnosis were lower.

Conclusion:
The burden of the disease is high. Early detection of cancer can save lives and reduce
health care costs. Studies evaluating the costs associated with cervical cancer as well as virusrelated
diseases in developing countries, calculating indirect costs and the impact of the disease on
family members, relatives, and especially the spouse of the affected women are recommended.
Controversial Issues of Abortion License According to Religious and Jurisprudential Laws in Iran: A Systematic Review
Authors: Ghodrati Fatemeh 
Published: February 2020

Background :
Increase in the number of unwanted pregnancies has been considered to be
among the health indices of the society. A large number of children, illegitimate children, and undesirable
fetal gender might increase the prevalence of illegal abortions.

Objective:
The present study aimed to investigate the abortion license according to religious and
jurisprudential laws in Iran.

Methods:
In this review, the related articles were found through searching of PubMed, Scopus,
Google Scholar, SID, and Magiran databases as well as Muslim authorities’ sites using the following
keywords: ethics, religious, abortion, and Islamic jurists’ fatwas, without any time limitations.

Results:
The majority of Islamic jurisprudents have considered abortion to be forbidden and nonreligious
at any stage of development in case there is no justifiable reason. In case of fetal anomalies
or threats to the mother’s life, abortion is allowed, based on the jurisprudential law (al-'usr wa
el-haraj) and written permission by the department of forensic medicine. However, abortion is not
permitted after ensoulment to the fetus, according to all scholars, with the exception of a few jurisprudents.

Conclusion:
The prohibition of abortion, in the view of most jurists, is not an absolute issue and
might include exceptions. According to jurisprudential laws (al-'usr wa el-haraj), the prohibition of
abortion has been abolished. Harassment and conflict in maternal-fetal life can also provide a license
for abortion.
GC-analysis, and Antioxidant, Anti-inflammatory, and Anticancer Activities of Some Extracts and Fractions of Linum usitatissimum
Authors: Morsi Eman A. , Ahmed Hend O. , Abdel-Hady Heba , El-Sayed Mortada , Shemis Mohamed A. 
Published: February 2020

Context:
Linum usitatissimum (Linn); known as Flaxseed, is one of the most important medicinal
plants traditionally used for health benefits and also as nutritional purposes.

Objective:
Estimation of total phenolic and flavonoid contents, and evaluation of the antioxidant, antiinflammatory
and anticancer activities have been performed on hexane, ethyl acetate, n-butanol, and
methanol extracts and also on fractions of methanol extract (hexane, ethyl acetate, and n-butanol).

Materials and Methods:
Phenolic and flavonoid contents were detected using spectrophotometric and
colorimetric assays. Antioxidant and anti-inflammatory activities were estimated in-vitro. Anticancer
activity of extracts was tested on Hepatocellular carcinoma cell line (HepG2) and breast cancer cell line
(MCF7).

Results:
The methanolic extract and its ethyl acetate fraction showed higher contents of total phenols
and flavonoids. Also, the methanolic extract showed a higher antioxidant activity. The butanolic and
ethyl acetate fractions at concentration 500μg/ml yielded a higher percent of inhibition of protein denaturation;
87.9% and 90%, respectively. The ethyl acetate fraction and the methanolic extract showed
an obvious anticancer activity against HepG2 and MCF7 (IC50=60±0.24 and 29.4±0.12μg. ml-1) and
(IC50=94.7±0.21 and 227±0.48μg. ml-1), respectively. The GC-MS analysis showed that the methanolic
extract had 32 compounds whereas the ethyl acetate and butanol fractions contained 40 and 36 compounds,
respectively.

Conclusion:
Flaxseed contains different biologically active compounds that have been found to possess
various activities, which can protect the human body against several diseases.
Metabolic Changes in Rat Plasma After Epilepsy by UPLC-MS/MS
Authors: Wen Congcong , Zhou Caiping , Jin Yongxi , Hu Yujie , Wang Hongzhe , Wang Xianqin , Yang Xuezhi 
Published: February 2020

Introduction:
Epilepsy is one of the most common neurological diseases in clinical practice.
The combined application of metabolomics technology plays a great advantage in the screening of biomarkers.

Methods:
In this study, Wistar rats were used as experimental subjects to model intractable epilepsy
and to detect the metabolic changes of small molecules in plasma. UPLC-MS/MS was used to determine
the small molecules in rat plasma. UPLC HSS C18 (2.1mm×100mm, 1.7 μm) column was used
for separation, column temperature of 40°C. The initial mobile phase was acetonitrile -0.3% formic
acid with gradient elution, the flow rate was 0.3 mL/min, total running time 4.0 min. Quantitative analysis
was performed with multi-response monitoring (MRM).

Results:
Compared to the control group, the L-Alanine and L-Arginine decreased in the Epilepsy group
(p<0.05); while Cytosine, Adenosine, L-Tyrosine, Citric acid, Fructose increased (p<0.05).

Conclusion:
In the screening of epilepsy biomarkers using metabolomics, various amino acids that
lead to increased energy production and neurotransmitter imbalance play an important role in epileptic
seizures.
Withdrawal Notice: CELP-IR: Caching Efficiency with Location Prediction based Invalidation and Replacement Policy
Authors: Gupta Ajay K. , Shanker Udai 
Published: February 2020

:
The article has been withdrawn at the request of the editor of the journal International Journal of Sensors, Wireless Communications
and Control

:

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.
The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php.

:

BENTHAM SCIENCE DISCLAIMER:

:

It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously
submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere
must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting
the article for publication the authors agree that the publishers have the legal right to take appropriate action against the
authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
Analysis of Contact Strength for Nutation Transmission with Conical Movable Teeth by Fractal Theory
Authors: Zhu Lili , Wang Guangxin , He Wenjie , Fan Wenzhong 
Published: February 2020

Background:
Nutation transmission with conical movable teeth is a patent about a new type
of spacial movable tooth drive that was developed based on the bevel planetary gear drive with a difference
in the number of small teeth.

Objective:
The aim of this study was to establish the fractal contact model and calculate the contact
strength of the center gear in the nutation transmission with conical movable teeth based on the M-B
fractal contact theory and also to demonstrate the validity of the present solution by comparing it with
the FEM results and the Hertz contact results.

Methods:
Based on the fractal theory, the relationship between the loads and the area for the tapered
roller teeth in contact with the center disk was obtained, and the four basic parameters were simulated
to analyze the effect of the fractal contact model in MATLAB.

Results:
The accuracy of the fractal contact model was verified using numerical simulation and analysis
of the relationship diagram for the real contact area and load and the contact area ratio chart with different
parameters.

Conclusion:
Based on the FEM theory, the Hertz elastic contact theory, and the fractal theory, the tooth
surface contact strength of the center disk was compared and analyzed, which enabled us to demonstrate
the validity of the present solution, and measures were taken to optimize and improve the followup
design of the nutation drive.
Factors Affecting the Wear Behavior of Monolithic Zirconia and the Antagonists: Literature Review
Authors: Borba Marcia , Benetti Paula , Furini Giordana P. , Weber Kátia R. , da Silva Tábata M. 
Published: February 2020

Background:The use of zirconia-based ceramics to produce monolithic restorations has increased due to improvements in the optical properties of the materials. Traditionally, zirconiabased ceramics were veneered with porcelain or glass-ceramic and were not directly exposed to the oral environment. Therefore, there are several doubts regarding the wear of the monolithic zirconia restoration and their antagonists. Additionally, different surface treatments are recommended to promote a smooth surface, including glaze and several polishing protocols. To support the correct clinical application, it is important to understand the advantages and limitations of each surface treatment.Objective:The aim of this short literature review is to investigate the factors that may affect the wear of monolithic zirconia restorations in service and their antagonists.Methods:Pubmed/Medline database was accessed to review the literature from a 10-year period using the keywords: zirconia, monolithic, prosthesis, wear. Both clinical and in vitro studies were included in the review.Results:Studies investigated the effect of several surface treatments, including grinding with diamond- burs, polishing and glazing, on the surface roughness, phase transformation and wear capacity of monolithic zirconia. The wear behavior of monolithic zirconia was frequently compared to the wear behavior of other ceramics, such as feldspathic porcelain, lithium disilicate-based glassceramic and leucite-reinforced glass-ceramic. Human tooth, ceramics and resin composites were used as antagonist in the investigations. Only short-term clinical studies are available (up to 2 years).Conclusion:Literature findings suggest that zirconia monolithic restorations are wear resistant and unlikely to cause excessive wear to the antagonist, especially when compared to feldspathic porcelain and glass-ceramics. Monolithic zirconia should be polished rather than glazed. Yet, none of the polishing systems studied was able to completely restore the initial surface conditions of zirconia after being adjusted with burs. More clinical evidence of the antagonist tooth wear potential of monolithic zirconia is needed.
Pharmacophore Based QSAR Modelling of Natural Leads in Antimicrobial Drug Design
Authors: Devi J. Renuka , Devi G. Nandhini , Bavanilatha M. , Gayathri G. , Kowsalyaleela K. , Anusha S. , Durga M. , Ramani R. , Sabitha K. 
Published: February 2020

:
To separate and optimize the bioactive fraction of Hemidesmus indicus as an
antimicrobial lead using in silico QSAR model development.

:
Hemidesmus indicus was extracted by soxhalation. The crude extract is fractionated using solvents
of different polarity and assessed for its antimicrobial activity. The bioactive fraction is further
analysed by GC-MS to analyse the constituents. These moieties were studied for their molecular
interaction using CoMFA based QSAR model development.

:
The bioactive fraction found to have antibacterial and antifungal activities. GC-MS revealed the
presence of eicosane, pthalic acid, oleanen 3 -yl acetate and substituted alkanes. Force field
analysis followed by simulation revealed that pthalic acid was found to have interaction with the
receptors.

:
Thus the integration of activity guided fractionation with cheminformatics may reveal the putative
leads in drug design. Pthalic acid analogues can thus be optimized further by subjecting to
preclinical drug studies.
Cluster Detection Mechanisms for Syndromic Surveillance Systems: Systematic Review and Framework Development
Authors: Yeng Prosper Kandabongee , Woldaregay Ashenafi Zebene , Solvoll Terje , Hartvigsen Gunnar 
Published: February 2020

Background
The time lag in detecting disease outbreaks remains a threat to global health security. The advancement of technology has made health-related data and other indicator activities easily accessible for syndromic surveillance of various datasets. At the heart of disease surveillance lies the clustering algorithm, which groups data with similar characteristics (spatial, temporal, or both) to uncover significant disease outbreak. Despite these developments, there is a lack of updated reviews of trends and modelling options in cluster detection algorithms.

Objective
Our purpose was to systematically review practically implemented disease surveillance clustering algorithms relating to temporal, spatial, and spatiotemporal clustering mechanisms for their usage and performance efficacies, and to develop an efficient cluster detection mechanism framework.

Methods
We conducted a systematic review exploring Google Scholar, ScienceDirect, PubMed, IEEE Xplore, ACM Digital Library, and Scopus. Between January and March 2018, we conducted the literature search for articles published to date in English in peer-reviewed journals. The main eligibility criteria were studies that (1) examined a practically implemented syndromic surveillance system with cluster detection mechanisms, including over-the-counter medication, school and work absenteeism, and disease surveillance relating to the presymptomatic stage; and (2) focused on surveillance of infectious diseases. We identified relevant articles using the title, keywords, and abstracts as a preliminary filter with the inclusion criteria, and then conducted a full-text review of the relevant articles. We then developed a framework for cluster detection mechanisms for various syndromic surveillance systems based on the review.

Results
The search identified a total of 5936 articles. Removal of duplicates resulted in 5839 articles. After an initial review of the titles, we excluded 4165 articles, with 1674 remaining. Reading of abstracts and keywords eliminated 1549 further records. An in-depth assessment of the remaining 125 articles resulted in a total of 27 articles for inclusion in the review. The result indicated that various clustering and aberration detection algorithms have been empirically implemented or assessed with real data and tested. Based on the findings of the review, we subsequently developed a framework to include data processing, clustering and aberration detection, visualization, and alerts and alarms.

Conclusions
The review identified various algorithms that have been practically implemented and tested. These results might foster the development of effective and efficient cluster detection mechanisms in empirical syndromic surveillance systems relating to a broad spectrum of space, time, or space-time.
PRAKTIK PENGASUHAN, KETERLIBATAN ORANG TUA DI SEKOLAH, KONSEP DIRI ANAK, DAN KESIAPAN SEKOLAH
Authors: Fauziah Hilda , Hastuti Dwi , Yuliati Lilik Noor 
Published: February 2020

School readiness before entering primary education is important for children to support future academic achievement. This study aims to identify and analyze parental characteristics, child characteristics, parenting practices, parental involvement in school, self-concept, and school readiness of children aged 5-6 years. This research was conducted in six selected kindergartens at Beji District, Depok City. Total of 100 children and their mothers as respondents who were selected using a convinient sampling method. Data were collected by self-report, observation, and interview methods. Data was analyzed by descriptive analysis using SPSS and influence analysis using smartPLS. The results showed that parenting practices, parental involvement in schools, and the child self concept was categorized is good, and the school readiness of children in categorized was very good. The results of influence analysis show that parenting practices directly influence to parent involvement in school, and the child's self-concept. Parenting practices also indirectly influence school readiness through the involvement of parents in the school. The other results show that parenting practices and parent involvement in schools directly influence significant positive on school readiness. Meanwhile, children's self-concept has no effect to school readiness. Overall parenting practice and parent involvement in school very important role of increasing children's school readiness. In the other hand, it’s necessary synergism between home and school environment to optimize child's self concept.
Penataan Struktur dan Kewenangan Komisi Pemilihan Umum, Badan Pengawas Pemilu dan Dewan Kehormatan Penyelenggara Pemilu dalam Upaya Mewujudkan Pemilihan Umum yang Demokratis di Indonesia.
Authors: Warjiyati Sri 
Published: February 2020

Pemilihan umum atau dalam istilah lain disebut Pemilu merupakan syarat yang mutlak untuk melaksanakan kedaulatan rakyat bagi negara demokrasi dan untuk mengokohkan dirinya sebagai negara demokratis. Sebuah Pemilu dikatakan demokratis atau tidak tergantung dari adanya badan atau lembaga penyelenggara Pemilu. Dalam rangka mewujudkan pemilu yang berkualitas dan berkapasitas, maka dibutuhkan lembaga penyelenggara pemilu yang profesional. Namun, hal tersebut akan sulit diwujudkan apabila antar lembaga pemilu itu sendiri yaitu antara “Komisi Pemilihan Umum (KPU), Badan Pengawas Pemilu (Bawaslu) dan Dewan Kehormatan Penyelenggara Pemilu (DKPP)” terus terjadi perbedan pendapat. Perbedaan pendapat ini terjadi karena adanya ketidakjelasan pengaturan penyelesaian masalah hukum pemilu yang tidak konsisten dan tidak pasti, terutama terkait mekanisme penyelenggaraan pemilu dalam lembaga penyelenggara pemilu sehingga pengaturannya harus diperbaiki dan secara tegas diperjelas tentang wewenang dan tanggungjawab masing-masing lembaga penyelenggara pemilu. Dalam penelitian ini penulis menggunakan metode penelitian hukum normatif dengan pendekatan perundang-undangan. Tujuan diadakannya penelitian ini sebagai kritik agar antara KPU, Bawaslu dan DKPP menjalankan kewenangannya dengan memperjelas mekanisme penyelenggara pemilu. Dengan penjelasan diatas, penulis menyimpulkan bahwa antara KPU, Bawaslu, dan DKPP harus memperjelas wewenangnya dan tanggungjawab masing-masing agar tidak menimbulkan perbedaan pendapat yang mana akan menghasilkan pemilu yang tidak demokratis.
Pengaruh Perencanaan Pajak Dan Insentif Non Pajak Terhadap Manajemen Laba Pada Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia Tahun 2013-2017
Authors: Sutrisno Mohamad , Astutie Yanti Puji 
Published: February 2020

The Effect of Tax Planning and Non-Tax Incentives toward Earnings Management at Manufacturing Companies listed on Indonesia Stock Exchange 2013-2017. Thesis, Tegal: Faculty of Economics, Pancasakti University Tegal. 2018. The purpose of this study is to examine the effect of tax planning and non-tax incentives simultaneously and partially toward earnings management at manufacturing companies listed on the Indonesia Stock Exchange in 2013-2017. This research is descriptive research with quantitative approach. The sample used is automotive sub-sector manufacturing companies and components listed in Indonesia Stock Exchange period 2013-2017. The number of companies sampled this research there are 45 companies by using purposive sampling method. While the data analysis method used is descriptive statistical test, classical assumption test, multiple linear regression analysis, simultaneous significance test (F test), test of individual parameter significance (T test) and coefficient of determination. Based on the results of research indicate that tax planning and non-tax incentive simultaneously have a significant effect toward earnings management with significance value 0,000. While partially tax planning, earnings pressure and firm size have significant effect to earnings management with value of significance respectively 0,037,0,000 and 0,049. As well as leverage and earnings bath partially no effect toward earnings management with a significance value of 0.436 and 0.146 respectively.