bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antenatal corticosteroid administration and early school age child development: A regression discontinuity study in British Columbia, Canada
Authors: Hutcheon Jennifer A. , Harper Sam , Liauw Jessica , Skoll M. Amanda , Srour Myriam , Strumpf Erin C. 
Published: December 2020

Background
There are growing concerns that antenatal corticosteroid administration may harm children’s neurodevelopment. We investigated the safety of antenatal corticosteroid administration practices for children’s overall developmental health (skills and behaviors) at early school age.

Methods and findings
We linked population health and education databases from British Columbia (BC), Canada to identify a cohort of births admitted to hospital between 31 weeks, 0 days gestation (31+0 weeks), and 36+6 weeks, 2000 to 2013, with routine early school age child development testing. We used a regression discontinuity design to compare outcomes of infants admitted just before and just after the clinical threshold for corticosteroid administration of 34+0 weeks. We estimated the median difference in the overall Early Development Instrument (EDI) score and EDI subdomain scores, as well as risk differences (RDs) for special needs designation and developmental vulnerability (<10th percentile on 2 or more subdomains). The cohort included 5,562 births admitted between 31+0 and 36+6 weeks, with a median EDI score of 40/50. We found no evidence that antenatal corticosteroid administration practices were linked with altered child development at early school age: median EDI score difference of −0.5 [95% CI: −2.2 to 1.7] (p = 0.65), RD per 100 births for special needs designation −0.5 [−4.2 to 3.1] (p = 0.96) and for developmental vulnerability of 3.9 [95% CI:−2.2 to 10.0] (p = 0.24). A limitation of our study is that the regression discontinuity design estimates the effect of antenatal corticosteroid administration at the gestational age of the discontinuity, 34 + 0 weeks, so our results may become less generalisable as gestational age moves further away from this point.

Conclusions
Our study did not find that that antenatal corticosteroid administration practices were associated with child development at early school age. Our findings may be useful for supporting clinical counseling about antenatal corticosteroids administration at late preterm gestation, when the balance of harms and benefits is less clear.
Prevalence and predictors of death and severe disease in patients hospitalized due to COVID-19: A comprehensive systematic review and meta-analysis of 77 studies and 38,000 patients
Authors: Dorjee Kunchok , Kim Hyunju , Bonomo Elizabeth , Dolma Rinchen 
Published: December 2020

IntroductionProgression of COVID-19 to severe disease and death is insufficiently understood.ObjectiveSummarize the prevalence of risk factors and adverse outcomes and determine their associations in COVID-19 patients who were hospitalized.MethodsWe searched Medline, Embase and Web of Science for case-series and observational studies of hospitalized COVID-19 patients through August 31, 2020. Data were analyzed by fixed-effects meta-analysis using Shore’s adjusted confidence intervals to address heterogeneity.ResultsSeventy-seven studies comprising 38906 hospitalized patients met inclusion criteria; 21468 from the US-Europe and 9740 from China. Overall prevalence of death [% (95% CI)] from COVID-19 was 20% (18–23%); 23% (19–27%) in the US and Europe and 11% (7–16%) for China. Of those that died, 85% were aged≥60 years, 66% were males, and 66%, 44%, 39%, 37%, and 27% had hypertension, smoking history, diabetes, heart disease, and chronic kidney disease (CKD), respectively. The case fatality risk [%(95% CI)] were 52% (46–60) for heart disease, 51% (43–59) for COPD, 48% (37–63) for chronic kidney disease (CKD), 39% for chronic liver disease (CLD), 28% (23–36%) for hypertension, and 24% (17–33%) for diabetes. Summary relative risk (sRR) of death were higher for age≥60 years [sRR = 3.6; 95% CI: 3.0–4.4], males [1.3; 1.2–1.4], smoking history [1.3; 1.1–1.6], COPD [1.7; 1.4–2.0], hypertension [1.8; 1.6–2.0], diabetes [1.5; 1.4–1.7], heart disease [2.1; 1.8–2.4], CKD [2.5; 2.1–3.0]. The prevalence of hypertension (55%), diabetes (33%), smoking history (23%) and heart disease (17%) among the COVID-19 hospitalized patients in the US were substantially higher than that of the general US population, suggesting increased susceptibility to infection or disease progression for the individuals with comorbidities.ConclusionsPublic health screening for COVID-19 can be prioritized based on risk-groups. Appropriately addressing the modifiable risk factors such as smoking, hypertension, and diabetes could reduce morbidity and mortality due to COVID-19; public messaging can be accordingly adapted.
An integrative systematic review of creative arts interventions for older informal caregivers of people with neurological conditions
Authors: Irons J. Yoon , Garip Gulcan , Cross Ainslea J. , Sheffield David , Bird Jamie 
Published: December 2020

Objective
We aimed to assess and synthesise the current state of quantitative and qualitative research concerning creative arts interventions for older informal caregivers of people with neurological conditions.

Methods
A systematic search was employed to identify studies that examined creative arts interventions for older informal caregivers, which were synthesised in this integrative review. We searched the following databases: MEDLINE, PubMed, EBSCO, CINAHL, EMBASE, PsycINFO, Cochrane Library, Scopus, Web of Science, and Google Scholar. We also backwards searched references of all relevant studies and inspected trials registers.

Results
Of the 516 studies identified, 17 were included: one was quantitative, nine were qualitative and seven used mixed methods. All included quantitative studies were pilot or feasibility studies employing pre- and post-test design with small sample sizes. Studies varied in relation to the type of creative intervention and evaluation methods, which precluded meta-analysis. Large effect sizes were detected in wellbeing measures following singing and art interventions. The qualitative synthesis highlighted that interventions created space for caregivers to make sense of, accept and adapt to their identity as a caregiver. Personal developments, such as learning new skills, were viewed positively by caregivers as well as welcoming the opportunity to gain cognitive and behavioural skills, and having opportunities to unload emotions in a safe space were important to caregivers. Group creative interventions were particularly helpful in creating social connections with their care-recipients and other caregivers.

Conclusions
The current review revealed all creative interventions focused on caregivers of people living with dementia; subsequently, this identified gaps in the evidence of creative interventions for informal caregivers of other neurological conditions. There are encouraging preliminary data on music and art interventions, however, little data exists on other art forms, e.g., drama, dance. Creative interventions may appeal to many caregivers, offering a range of psycho-social benefits. The findings of the current review open the way for future research to develop appropriate and creative arts programmes and to test their efficacy with robust tools.
Novel computer-based assessments of everyday visual function in people with age-related macular degeneration
Authors: Higgins Bethany E. , Taylor Deanna J. , Bi Wei , Binns Alison M. , Crabb David P. 
Published: December 2020

Purpose
To test the hypothesis that the performance in novel computer-based tasks of everyday visual function worsens with disease severity in people with non-neovascular age-related macular degeneration.

Methods
Participants with and without non-neovascular age-related macular degeneration (≥60 years, minimum logMAR binocular visual acuity 0.7) performed a series of standard visual function tests and two novel computer-based tasks. In a visual search task, participants had to locate an image of a single real-world object within an array of 49 distractor images. Next, in a series of simulated dynamic driving scenes, participants were asked to identify one or two approaching real-world road signs and then select these road signs from four options. Outcome measures were median response times and total correct responses.

Results
Forty-nine participants had no macular disease (n = 11), early/intermediate age-related macular degeneration (n = 16) or geographic atrophy (n = 22). Groups were age-similar with median (interquartile range) logMAR visual acuity of 0.00 (-0.08,0.12), 0.13 (-0.08,0.70) and 0.32 (0.12,0.70) respectively. Median (interquartile range) visual search response times were 1.9 (1.0,2.4), 1.8 (1.1,3.7) and 2.4 (1.2,6.0) seconds respectively. Median (interquartile range) road sign response times (single road signs) were 1.2 (0.4,1.7), 1.5 (0.9,2.8) and 1.8 (1.0,5.5) seconds respectively. Median (interquartile range) road sign response times (double road signs) were 1.7 (0.7,2.4), 2.3 (1.2,3.1) and 2.5 (1.7,6) seconds respectively. Participants with geographic atrophy recorded slower response times in all tasks and over 50% performed outside the normative limit for task performance. There were no significant differences between groups in total correct responses across all tasks.

Conclusions
In a novel computer-based assessment, people with increasing severity of age-related macular degeneration take longer to perform visual search of everyday objects and take longer to identify road signs than those with no age-related macular degeneration. These novel assessments could be useful as patient-relevant, secondary outcomes for clinical trials.
Transrectal Endoscopic Ultrasound-Guided Drainage of a Tubo-Ovarian Abscess Via a Lumen-Apposing Metal Stent
Authors: Shah Ruchit N. , West Sara , Sweeney Kaitlyn M. , Mehta Minesh , Diehl David L. 
Published: December 2020

ABSTRACT
Tubo-ovarian abscess (TOA) is a potentially lethal condition, often requiring a combination of medical and surgical interventions. Endoscopic ultrasound (EUS)-guided drainage is a known modality for safe and effective management of pelvic fluid collections, but its role for the treatment of TOA is not well documented. We report the first known case of successful treatment of a large TOA with EUS-guided transrectal drainage using a lumen-apposing metal stent.
A LEISHMANIOSE TEGUMENTAR AMERICANA E SEUS FATORES DE RISCOS SOCIOAMBIENTAIS NO MUNICÍPIO DE TUCURUÍ, PARÁ, BRASIL: ANÁLISE ESPACIAL E EPIDEMIOLÓGICA
Authors: De Oliveira Rafael Aleixo Coelho , Miranda Claudia do Socorro Carvalho de , Guedes Juan Andrade , Bichara Cléa Nazaré Carneiro , Pereira Alba Lucia Ribeiro Raithy , Martins Claudia Nazaré de Souza Almeida Titan , Cabeça Ana Lydia Lédo de Castro Ribeiro , Filgueiras Tainara Carvalho Garcia Miranda , Filgueiras Tainã Carvalho Garcia Miranda , Faria Camylle Maia Costa , Gonçalves Nelson Veiga 
Published: December 2020

O estudo objetivou analisar a distribuição espacial da LTA em Tucuruí e a sua relação com variáveis socioambientais e epidemiológicas, no período de 2012 a 2016. Os dados epidemiológicos foram obtidos no SINAN da SESPA e os cartográficos, populacionais, unidades de conservação e terras indígenas, foram obtidos no IBGE. Os ambientais foram obtidos no PRODES. As análises dos casos e da relação espacial destes com o desflorestamento utilizaram o Bioestat 5.0 e o ArcGis 10.5.1, respectivamente. O município teve 286 casos confirmados, distribuídos de forma não homogênea em seus setores censitários. Os indivíduos mais acometidos foram do sexo masculino, adultos, pardos, baixo nível de escolaridade e moradores da zona urbana. Foi verificado na série histórica um aumento de casos de LTA e do incremento do desmatamento. A análise espacial mostrou a presença de dois aglomerados de casos localizados na área urbana. Foi observado também a existência de um mosaico de ocupações e terras indígenas. A LTA é um grande e complexo problema de saúde pública em Tucuruí, relacionado à fatores de riscos socioambientais, gerados e condicionados pela insuficiência de políticas públicas no município, que pode ter contribuído para a exposição da população local a vários fatores de risco da doença.
Aristóteles: educação moral e a formação do caráter
Authors: Siquieroli Rosane Viola 
Published: December 2020

Aristóteles: educação moral e a formação do caráter
Resumo: O presente artigo se propõe a apresentar uma visão a respeito das noções aristotélicas sobre a aquisição das virtudes morais e ainda estabelecer uma relação com a educação do caráter. Aristóteles atribui à habituação o papel de cultivar na alma humana a motivação para a ação correta. Num primeiro momento será discutido o papel das virtudes e em seguida será feita uma exposição sobre o método aristotélico de aquisição da virtude moral; tendo como resultado a criação e o desenvolvimento da virtude do caráter.
Palavras-chave: Virtude de caráter, Aristóteles, Educação moral
Aristotle: moral education and character formation
Abstract: This article proposes to present a vision about the Aristotelian notions about the acquisition of the moral virtues and also to establish a relation with the education of the character. Aristotle attributes to habituation the role of cultivating in the human soul the motivation for right action. In a first moment the role of the virtues will be discussed and then an exposition will be made on the Aristotelian method of acquisition of the moral virtue and as a consequence the creation and the development of the virtue of the character and the virtuous agent.
Keywords: virtue of character, Aristotle, moral education
Data de registro: 12/11/2018
Data de aceite: 13/02/2019
O conhecimento das ideias em Schopenhauer
Authors: Salvio Thiago de Souza 
Published: December 2020

O conhecimento das ideias em Schopenhauer
O intuito da presente comunicação é deslindar os conceitos fundamentais do que podemos denominar a “Filosofia da Arte” do pensador alemão Arthur Schopenhauer. Este tema propriamente dito não leva o título considerado acima, mas outrossim, “Metafísica do Belo”; com as noções de Ideia, Vontade, Sujeito puro do conhecimento, Gênio, buscaremos obter a compreensão do conhecimento ideal que o autor em pauta entende por contemplação estética, para isto, vamos examinar seus textos principais.
Palavras-chave: Filosofia da Arte; Metafísica do Belo; Ideias; Schopenhauer.
The knowledge of the ideas in Schopenhauer
Abstract: The purpose of this communication is to unravel the fundamental concepts of what we can call the "Philosophy of Art" of the German thinker Arthur Schopenhauer. This theme itself does not take the title considered above, but otherwise, "Metaphysics of the Beautiful"; with the notions of Idea, Will, Pure subject of knowledge, Genius, we will seek to obtain the understanding of the ideal knowledge that the author in question understands by aesthetic contemplation, for this, we will examine his main texts.
Key-words: Philosophy of Art; Metaphysics of the Beautiful; Ideas; Schopenhauer.
Data de registro: 27/11/2018
Data de aceite: 27/03/2019
O conceito de fenomenologia de Martin Heidegger em Ser e Tempo
Authors: De Souza Alisson Matutino 
Published: December 2020

O conceito de fenomenologia de Martin Heidegger em Ser e Tempo
Resumo: O objetivo de nosso artigo é analisar o conceito de fenomenologia heideggeriano no § 7 da obra Ser e Tempo. Procuramos examinar em que medida Heidegger pretende precisar a necessidade de re-pensar a questão do sentido do ser, devido à ausência de uma reposta adequada sobre o mesmo na História da Filosofia. Detivemo-nos a analisar qual o sentido da reelaboração do lema: “de volta às coisas elas-mesmas” que Heidegger trabalha em relação ao seu mestre Husserl. Propomos examinar a posição especial de Heidegger face ao problema da articulação da ontologia com a fenomenologia. E qual a inovação é acrescentada a Fenomenologia enquanto método quando Heidegger a interpreta como uma Hermenêutica da factualidade para seu projeto filosófico.
Palavras-chave: Fenômeno, Logos, Fenomenologia, Ontologia e c.
The concept of Phenomenology in Heidegger's Being and Time
Abstract: The objective of our article is to analyze the concept of heideggerian phenomenology in § 7 of the work Being and Time. We try to examine to what extent Heidegger intends to specify the necessity of re-thinking the question of the sense of being, due to the absence of an adequate answer on the same in the History of Philosophy. We were left to analyze the meaning of the re-elaboration of the motto: "back to the things themselves" that Heidegger works in relation to his master Husserl. We propose to examine Heidegger's special position on the problem of articulation of ontology with phenomenology. And what innovation is added to Phenomenology as a method when Heidegger interprets it as a Hermeneutics of factuality for his philosophical project.
Keywords: Phenomenon, Logos, Phenomenology, Ontology and Hermeneutics
Data de registro: 06/11/2018
Data de aceite: 25/02/2019
A imaginação como fundamento das ciências experimentais
Authors: Santos Figueiredo Pablo Henrique 
Published: December 2020

Resumo: David Hume, em seus livros Tratado da Natureza Humana e Investigação Acerca do Entendimento Humano, propõe a divisão da mente humana em percepções fortes e vivas, as quais recebem o nome de impressões, e suas cópias, que, por sua vez, recebem o nome de ideias. Estas percepções da mente também se dividem em duas: memória e imaginação. A primeira, com maiores graus de força e vivacidade, e a segunda com menores graus de força e vivacidade. As percepções da mente se relacionam a partir das relações filosóficas, que são princípios de associação e dissociação de ideias. A relação da imaginação com as ciências empíricas é o principal aspecto deste trabalho, de modo que, no decorrer do texto, os aspectos que fomentam esta relação serão trabalhados, ilustrando a importância que tem a imaginação no advento das ciências experimentais.
Palavras-chave: Hume; Imaginação; Ciência
The imagination as foundation of the experimental sciences
Abstract: David Hume, in his books A Treatise Of Human Nature and An Enquiry Concerning Human Understanding, proposes the division of human mind in in strong, lively perceptions, which are called impressions, and their copies, which, in turn, receive the name of ideas. These perceptions of the mind are also divided into two: memory and imagination. The first, with higher degrees of force and vivacity, and the second with lower degrees of force and vivacity. The perceptions of the mind are related from the philosophical relations, which are the principles of association and dissociation of ideas. The ratio of the imagination with the empirical sciences is the main aspect of this work, so that, throughout the text, aspects that foster this relationship will be worked out, illustrating the importance of the imagination in the advent of experimental sciences.
Keywords: Hume; Imagination; Science

Data de registro: 25/11/2019
Data de aceite: 04/02/2020
Tradução dos versos 31-93 do Livro III Da obra De Rerum Natura de Tito Lucrécio Caro
Authors: Perente de Barros Thales 
Published: December 2020

Tradução dos versos 31-93 do Livro III Da obra De Rerum Natura de Tito Lucrécio Caro (99-55A.C.) Edição para o texto latino: DUFF, 1903.

Data de registro: 07/04/2020
Data de aceite: 25/05/2020
ideias abstratas em Locke como solução para o problema dos universais
Authors: Da Silva Danival Lucas 
Published: December 2020

O objetivo desse artigo é analisar o impacto da proposta de Locke, em relação às ideias abstratas, na discussão em torno do problema dos universais. Para Locke, a solução desse problema passa pela rejeição do realismo - teoria fortemente defendida pela tradição e ainda presente no pensamento filosófico nos dias de hoje. Nesse artigo falaremos sobre os avanços conquistados pelo empirista inglês e discutiremos os pontos frágeis de seus argumentos. Defenderemos que é possível construir uma refutação definitiva do realismo, baseando-nos no conceito de ideias abstratas e nas evidências reveladas pelo avanço das ciências.
Abstract ideas in Locke as a solution to the problem of universals
Abstract : The purpose of this article is to analyze the impact of Locke's proposal, in relation to abstract ideas, in the discussion around the problem of universals. For Locke, the solution to this problem requires the rejection of realism - a theory strongly defended by tradition and still present in philosophical thought today. In this article we will talk about the advances achieved by this english empiricist and discuss the weak points of his arguments. We will argue that it is possible to construct a definitive refutation of realism, based on the concept of abstract ideas and on the evidences revealed by the advancement of science.
Identidade, intersubjetividade e dignidade humana: reflexões sobre a política do reconhecimento de Charles Taylor
Authors: Danner Fernando , Barbosa Gustavo Adolfo Suckow 
Published: December 2020

Em sua teoria política do reconhecimento, Taylor trata de um dos grandes desafios das sociedades contemporâneas: o desafio do multiculturalismo. O pluralismo de ideias, articulado de forma racional, é o fundamento de uma boa democracia; no entanto, para Taylor, não basta que haja o pluralismo ou a diferença, mas é fundamental que a relação intersubjetiva desses indivíduos se desenvolva com o devido respeito à diversidade; portanto, é fundamental que exista o reconhecimento do outro, um olhar para a alteridade e para a formação da identidade dos indivíduos, sendo esta última entendida como uma característica fundamental dos seres humanos. Neste texto, refletimos sobre três ideias fundamentais presentes no texto A política do reconhecimento: (i) em que consiste o reconhecimento; (ii) por que ele é uma necessidade humana vital para a formação saudável e igualitária tanto da identidade do indivíduo como de uma determinada cultura; e (iii) a crítica a neutralidade da posição liberal e a importância de uma meta coletiva forte.
Identity, intersubjectivity and human dignity: some thought on Charles Taylor’s politics of recognition
Abstract: In his theory of recognition, Taylor thematizes one of the greatest challenges of contemporary societies: the challenge of multiculturalism. The pluralism of ideas, articulated in a rational way, is the fundament of a solid democracy; however, according to Taylor, is it not sufficient the existence of pluralism or difference, but it is central that the intersubjective relationship of these subjects could be developed with the correct respect to diversity; therefore, it is fundamental the existence of the recognition of the other, a looking to the alterity and the formation of the identity of the individuals, this last understood as a basic characteristic of human beings. In this paper, we will reflect on three key ideas developed by Taylor’s The politics of recognition: (i) the sense of the recognition; (ii) why it is a vital human need to the sustainable and egalitarian formation to both individual identity and cultures; and (iii) the criticism of the neutrality of the liberal position, as the importance of the strong collective aim.