bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute kidney injury, seizures, and hypertonic hyponatremia secondary to mannitol intoxication in a dog
Authors: Clabots Maëlle F. , Gaillard Elodie , Aumann Marcel 
Published: October 2019

AbstractObjectiveTo describe a case of mannitol overdose associated with acute kidney injury (AKI), hypertonic hyponatremia, and neurologic abnormalities in a dog.Case SummaryA 10‐year‐old intact male Shiba Inu dog was referred to the emergency service of a veterinary teaching hospital for inappetence and acute onset of seizures. The dog had received 2 IV boluses of 3 g/kg of mannitol in less than 24 hours for a glaucoma crisis. Twelve hours after the second injection, the dog became inappetant and developed 2 generalized seizures. Seizure activity was treated with diazepam (0.5 mg/kg IV). Serum biochemistry profile showed severe hyponatremia and hypochloremia, mild hypokalemia, marked increased creatinine (381 µmol/L [44–133 µmol/L]) and moderately increased BUN (13.8 mmol/L [1.6–10.9 mmol/L]). Urinalysis revealed a urine specific gravity of 1.018, glucosuria, proteinuria, pigmenturia and the presence of vacuolized tubular epithelial cells. A presumptive diagnosis of mannitol intoxication was made based on the high dose of mannitol, severe hyponatremia, neurological abnormalities suggestive of intracranial disease, AKI, and urine cytology. Initial calculated plasma osmolality was 263.4 mOsm/kg and measured plasma osmolality was 332 mOsm/kg with an osmolal gap of 68.6 mOsm/kg, confirming the presence of an unmeasured solute attributed to mannitol. Treatment consisted of fluid therapy and supportive care. On day 3, osmolal gap had resolved and serum creatinine concentration returned to normal within 12 days.New or Unique Information ProvidedMannitol intoxication has been reported in human medicine. This case report is, to our knowledge, the first to describe AKI, hypertonic hyponatremia, and neurological abnormalities secondary to mannitol overdose in a dog.
Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data
Authors: Shih Andrew W. , Apelseth Torunn Oveland , Cardigan Rebecca , Marks Denese C. , Bégué Stéphane , Greinacher Andreas , de Korte Dirk , Seltsam Axel , Shaz Beth H. , Wikman Agneta , Barty Rebecca L. , Heddle Nancy M. , Acker Jason P. ,   The QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative
Published: October 2019

AbstractIntroductionIn vitro qualitative differences exist in red cell concentrates (RCCs) units processed from whole blood (WB) depending on the method of processing. Minimal literature exists on differences in processing and variability in quality data. Therefore, we collected information from blood manufacturers worldwide regarding (1) details of WB collection and processing used to produce RCCs and (2) quality parameters and testing as part of routine quality programmes.MethodsA secure web‐based survey was developed, refined after pilot data collection and distributed to blood centres. Descriptive analyses were performed.ResultsData from ten blood centres in nine countries were collected. Six blood centres (60%) processed RCCs using the top‐and‐top (TAT) method which produces RCCs and plasma, and eight centres (80%) used the bottom‐and‐top (BAT) which additionally produces buffy coat platelets. Five of the centres used both processing methods; however, four favoured BAT processing. One centre utilized the Reveos automated system exclusively. All centres performed pre‐storage leucoreduction. Other parameters demonstrated variability, including active cooling at collection, length of hold before processing, donor haemoglobin limits, acceptable collection weights, collection sets, time to leucoreduction, centrifugation speeds, extraction devices and maximum RCC shelf life. Quality marker testing also differed amongst blood centres. Trends towards higher RCC unit volume, haemolysis and residual leucoctyes were seen in the TAT compared with BAT processing across centres.ConclusionMethods and parameters of WB processing and quality testing of RCCs differ amongst surveyed blood manufacturers. Further studies are needed to assess variations and to potentially improve methods and product quality.
Reconceptualizing Aunty as an address term in urban multilingual Malaysia
Authors: Lee Sarah , Shanmuganathan Thilagavathi 
Published: October 2019

AbstractThis paper explores contact reconceptualizations of English Aunty as an address term in Greater Kuala Lumpur, Malaysia. In this multiethnic and multilingual city, Aunty is used in local discourses to address older females across different languages and regardless of whether Addressee is related to the Addresser. Moreover, usage of Aunty is extensive, covering a range of social roles, identities, and interpersonal relations that reflect acculturations to a context where diverse traditional cultural norms, multilanguage mixing, and modernity effects, are simultaneously salient. Using the Cultural Linguistics framework (Sharifian, 2017a, 2017b), it is demonstrated that long‐established Malaysian cultural priorities, race (ethnicity) and modern as status (modernity values) can help account for the potential range of usages of Malaysian Aunty.
EBP Implementation Leadership of Frontline Nurse Managers: Validation of the Implementation Leadership Scale in Acute Care
Authors: Shuman Clayton J. , Ehrhart Mark G. , Torres Elisa M. , Veliz Philip , Kath Lisa M. , VanAntwerp Katherine , Banaszak‐Holl Jane , Titler Marita G. , Aarons Gregory A. 
Published: October 2019

AbstractBackgroundFrontline nurse managers influence the implementation of evidence‐based practices (EBP); however, there is a need for valid and reliable instruments to measure their leadership behaviors for EBP implementation in acute care settings.AimThe aim of this study was to evaluate the validity and reliability of the Implementation Leadership Scale (ILS) in acute care settings using two unique nurse samples.MethodsThis study is a secondary analysis of ILS data obtained through two distinct multisite cross‐sectional studies. Sample 1 included 200 registered nurses from one large Californian health system. Sample 2 was 284 registered nurses from seven Midwest and Northeast U.S. hospitals. Two separate studies by different research teams collected responses using written and electronic questionnaires. We analyzed each sample independently. Descriptive statistics described individual item, total, and subscale scores. We analyzed validity using confirmatory factor analysis and within‐unit agreement (awg). We evaluated factorial invariance using multigroup confirmatory factor analyses and evaluating change in chi‐square and comparative fit index values. We evaluated reliability using Cronbach's alpha.ResultsConfirmatory factor analyses in both samples provided strong support for first‐ and second‐order factor structure of the ILS. The factor structure did not differ between the two samples. Across both samples, internal consistency reliability was strong (Cronbach's alpha: 0.91–0.98), as was within‐unit agreement (awg: 0.70–0.80).Linking Evidence to ActionFrontline manager implementation leadership is a critical contextual factor influencing EBP implementation. This study provides strong evidence supporting the validity and reliability of the ILS to measure implementation leadership behaviors of nursing frontline managers in acute care. The ILS can help clinicians, researchers, and leaders in nursing contexts assess frontline manager implementation leadership, deliver interventions to target areas needing improvement, and improve implementation of EBP.
K-Factor Solution for Combined Braced–Unbraced Offshore Jacket Frames
Authors: Ku Albert , Chen Jieyan , Gunzelman Stephen 
Published: October 2019

Abstract
Many offshore jackets have no braces between the top of jacket and the bottom of topsides deck. This can be either due to the installation requirement and/or an effort to reduce wave loads. This kind of jacket bay is a portal frame. For the design of portal frame columns, the current offshore standards point to the unbraced frame alignment chart solution from onshore standards such as the American Institute of Steel Construction (AISC). In this paper, we will show that the AISC alignment chart unbraced frame K-factor solution is conservative for offshore applications, and perhaps too conservative. This is because the traditional alignment chart assumes that the entire structure is a moment frame. In offshore applications, the unbraced frame is almost always combined with braced frames from above and/or below. In this paper, we will derive a K-factor solution that is suitable for a braced/unbraced frame combination. This solution is validated with structural buckling finite element method (FEM) analyses of typical offshore frames. Design implications from using the traditional alignment chart versus current new K-factor solution are also discussed.
Influence of the Friction Block Shape and Installation Angle of High-Speed Train Brakes on Brake Noise
Authors: Quan Xin , Mo Jiliang , Huang Bo , Tang Bin , Ouyang Huajiang , Zhou Zhongrong 
Published: October 2019

Abstract
In this study, experiments are conducted to evaluate the effects of friction block shapes and installation angles on the brake noise of high-speed trains on a customized small-scale brake dynamometer. Friction blocks in three different shapes (circle, triangle, and hexagon) and triangular/hexagonal friction blocks at different installation angles are used in the tests. The results indicate that the circular and triangular blocks exhibit low sound pressure with multiple harmonics, whereas the hexagonal friction block produces the highest sound pressure with a single dominant frequency. This difference is attributed to the high contact pressure and severe wear on the surface of the hexagonal friction block. Differences in the installation angle of the triangular/hexagonal friction blocks affect wear debris behavior, distribution of contact pressure, and contact state of the friction interface, consequently influencing noise performance.
Co-Integration-Based Compensation Technique for Dynamic Load Effects on the Electro-mechanical Impedance Method
Authors: Jie Xiaoluo , Qu Wenzhong , Xiao Li , Lu Ye 
Published: October 2019

Abstract
The electro-mechanical (EM) admittance signals acquired from piezoelectric transducers (PZT) surface bonded to the host structure are often used for structural health monitoring (SHM). However, it is well known that the method is susceptible to contamination from environmental and operational conditions. This paper introduces a co-integration method to remove dynamic load effects from electro-mechanical admittance data. The proposed method is based on the concept of co-integration that is partially built on the analysis of the non-stationary behavior of time series. Instead of directly using admittance signatures of PZT for damage detection, the analysis of the co-integrated residual obtained from the co-integration procedure of EM admittance responses and the resonant peaks frequency of the real part of admittance (conductance) are chosen as co-integrated variables. The experiments of aluminum beam bolt loosening identification, which is under dynamic stress, were carried out to verify the effectiveness of the proposed method. The results showed that the method can isolate damage-sensitive features from stress variations, so as to successfully detect the existence of damage.
Optimum Design of a New Tuned Inerter-Torsional-Mass-Damper Passive Vibration Control for Stochastically Motion-Excited Structures
Authors: Tai Wei-Che 
Published: October 2019

Abstract
The inerter is referred to as a two-terminal device that provides inertial forces proportional to the relative accelerations between its two terminals. It has been widely applied in vibration control due to its mass amplification effect. In this paper, a new inerter-based damper is proposed to take advantage of the mass amplification effect, which consists of the classic rack-pinion inerter in conjunction with a torsional tuned mass damper. Unlike any other topologies of inerter-based dampers, the torsional mass damper is connected to the pinion of the inerter via a rotational spring and viscous damper. As a result, the weight of the torsional mass damper can be significantly reduced. The proposed damper is applied to single-degree-of-freedom primary structures and a two degrees-of-freedom structure, and the H2 optimization is conducted to obtain the optimum tuning ratio and damping ratio analytically. When comparing the proposed damper with its counterpart reported in the literature, the proposed damper achieves 20–70% improvement when their weights are identical.
Operational Control of Mixing Enhancement and Far-Field Jet Noise Suppression Using Downstream Fluidic Injection
Authors: Rajput Pankaj , Kumar Sunil 
Published: October 2019

Abstract
A novel fluid injection scheme is analyzed for its ability to suppress the far-field jet noise using multiple radial microjets placed downstream from the nozzle exhaust. Contrary to other previous research studies, which injected fluid either inside the nozzle or just at the nozzle exhaust, this injection scheme uses a coaxial injector tube to inject multiple equally spaced microjets perpendicular to the jet axis at an axial location downstream from the nozzle exhaust. Microjet injection closer to the jet axis leads to the formation of a counter rotating vortex pair (CVP) close to the injection location which subsequently breaks down into streamwise vortices as the microjet bends and follows the flow direction. Microjet injection pressure and angle of injection play a crucial role in determining the jet trajectory, penetration, and the strength of the CVP formed. The effect of these parameters on the far-field acoustic radiation is evaluated in this study. Detailed large eddy simulations are performed for a nozzle–injector setup operating at Mach 0.9 jet with Reynolds number ≈106 to help understand the aerodynamic and acoustic features of the interaction of this fluid injection scheme with the main jet.
A toddler with a persisting limp after a minor trauma
Authors: Trombetta Andrea , Conversano Ester , Cozzi Giorgio , Taddio Andrea , Murru Flora Maria , Barbi Egidio 
Published: October 2019

­A 3-year-old toddler was admitted for a 5-day history of worsening painful limping on his left leg. History was remarkable only for a minor trauma 2 days before the onset of symptoms; the boy fell on his buttocks but was walking normally in the following days. No fever was reported. Pain was also present at night, with no response to oral ibuprofen.On physical examination, the patient refused to stand on his left leg, palpation of the left buttock evoked pain, and exorotation and abduction of the left hip were only moderately limited, without local signs of inflammation such as redness, swelling or skin warming. Blood tests showed elevated erythrocyte sedimentation rate (ESR) (98 mm/hour, normal value <20 mm/hour) with normal C reactive protein (CRP) level (0.5 mg/dL, normal value <0.5 mg/dL). His white cell count was 12 110 x 109/L, haemoglobin was 127 g/L and PLT was 430 x 109/L. Creatine kinase values were within the normal range.An X-ray of the pelvis was unremarkable. An ultrasound of the left hip showed a 2 mm articular effusion.QuestionsBased on the clinical picture and laboratory tests, what is the most likely diagnosis?Perthes disease.Pyomyositis.Septic arthritis.Bone fracture.Leukaemia.What test could confirm the diagnosis?Bone scintigraphy.CT.Bone marrow aspirate.MRI.Intra-articular puncture.What is the mainstay of management of this condition?Wait and see.Surgical excision.Antibiotic course.Antineoplastic treatment.Answers can be found on page 2.
Prevalence and characteristics of polycystic ovary syndrome in Brazilian women: protocol for a nation-wide case–control study
Authors: Spritzer Poli Mara , Marchesan Lucas B , Santos Betânia R , Cureau Felipe V , Oppermann Karen , Reis Rosana Maria dos , Ferriani Rui A , Weiss Rita , Meirelles Ricardo , Candido Ana Lucia , Reis Fernando M 
Published: October 2019

IntroductionBrazil is a large country, with a population of mixed ethnic background and broad variation in dietary and physical activity traits across its five main regions. Because data on Brazilian women with polycystic ovary syndrome (PCOS) are still scarce, a nation-wide collaborative study was designed to determine the prevalence of metabolic and reproductive abnormalities and the presence of anxiety and depression in Brazilian women with PCOS. In addition, the study aims at describing how these characteristics are distributed across PCOS phenotypes and at detecting associations with regional demographic and lifestyle aspects, genetic variants, and epigenetic markers.Methods and analysisThe Brazilian PCOS study is being conducted in the outpatient clinics of eight university hospitals within the public healthcare network (Unified Health System) across the country. Additional centres will be included following completion of the research ethics approval process. The sample includes women with PCOS according to Rotterdam criteria at inclusion in the study and a control group of healthy women matched by age, socioeconomic status and geographical region. Data will be collected in each centre and incorporated into a unified cloud database. Clinical, demographic, socioeconomic, psychological, metabolic, epigenetic and genotypic variables will be evaluated. The data resulting from this study will be useful to guide specific public strategies for primary and secondary prevention of metabolic and reproductive comorbidities in the PCOS population of Brazil.Ethics and disseminationThe study protocol was approved by each local Research Ethics Committee. Written informed consent will be obtained from each participant. During data collection, analysis and publication, care will be taken to ensure confidentiality of participant information. Study results will be published in peer-reviewed journals and disseminated at international conferences. This research protocol was registered with the Research Ethics Committee of HCPA, through Plataforma Brasil.Trial registration numberCAAE 18082413.9.1001.5327
Association between the number of teeth and frailty among Chinese older adults: a nationwide cross-sectional study
Authors: Gu Yaohua , Wu Wenwen , Bai Jinbing , Chen Xuyu , Chen Xiaoli , Yu Liping , Zhang Qing , Zou Zhijie , Luo Xianwu , Pei Xianbo , Liu Xin , Tan Xiaodong 
Published: October 2019

ObjectivesTo explore the association between the number of teeth and frailty among older Chinese adults using a nationally representative sample.DesignCross-sectional analysis was carried out using the 2014 wave data from the Chinese Longitudinal Healthy Longevity Survey, which used a targeted random-sampling design.SettingThis research was conducted in communities from nearly half of the counties and cities in 22 out of 31 provinces throughout China.ParticipantsOf the 6934 interviewees aged ≥65 years, the final analysis included 3635 older adults who had completed the 2014 wave survey on the variables included in the study.Primary and secondary outcome measuresOutcome variables included frailty, measured by the Frailty Index, and number of teeth. Covariates included demographic characteristics (ie, age, sex, co-residence, marital status, years of education and financial support), body mass index (BMI) and health behaviours (ie, smoking, drinking and exercise). A univariate logistic regression was used to test the factors associated with frailty. A multiple logistic regression model was used, using the frailty score as the dependent variable and the number of teeth together with significant covariates as the independent variables.ResultsThe prevalence of frailty was 27.68%. The mean number of teeth present was 9.23 (SD=10.03). The multiple logistic regression showed that older adults’ demographic variables, health behaviours, BMI, tooth number and chewing pain were significantly associated with frailty. After adjusting for the covariates, older adults with fewer teeth had significantly higher odds of frailty than those with 20 or more teeth (no teeth: OR=2.07, 95% CI 1.53 to 2.80; 1 to 10 teeth: OR=1.77, 95% CI 1.31 to 2.38), except for older adults with 11 to 20 teeth (OR=1.30, 95% CI 0.93 to 1.82).ConclusionsThe presence of fewer teeth is significantly associated with frailty status among older Chinese adults. Future studies are needed to explain the specific mechanisms underlying how oral health status is associated with frailty.
Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities
Authors: Vargas Sylvanna Maria , Wennerstrom Ashley , Alfaro Nancy , Belin Thomas , Griffith Krystal , Haywood Catherine , Jones Felica , Lunn Mitchell R , Meyers Diana , Miranda Jeanne , Obedin-Maliver Juno , Pollock Miranda , Sherbourne Cathy D , Springgate Benjamin F , Sugarman Olivia K , Rey Emily , Williams Clarence , Williams Pluscedia , Chung Bowen 
Published: October 2019

IntroductionDepression is the leading cause of adult disability and common among sexual and gender minority (SGM) adults. The current study builds on findings showing the effectiveness of depression quality improvement (QI) and delivery of cognitive behavioural therapy (CBT) skills provided by community health workers in reducing depression. Depression QI approaches across healthcare and social/community services in safety-net settings have shown improvements in mental wellness, mental health quality of life and depression over 12 months. Further, a randomised study showed improved depression among low-income racial/ethnic minorities enrolled in a CBT-informed resiliency class (Building Resilience and Increasing Community Hope (B-RICH)). The current protocol describes a comparativeness effectiveness study to evaluate whether predominantly low-income, SGM racial/ethnic minority adults randomised to a CBT-informed resiliency class have improvements in depressive symptoms over and above community-engaged QI resources and training only.Methods and analysisThe study approached three clusters of four to five programs serving predominantly SGM and racial/ethnic minority communities in the USA: two clusters in Los Angeles, California, and one in New Orleans, Louisiana. Clusters are comprised of one primary care, one mental health and two to three community agencies (eg, faith-based, social services/support, advocacy). All programs received depression QI training. The current study employed a community-partnered participatory research model to adapt the CBT-informed resiliency class, B-RICH+, to SGM communities. Study participants were screened and recruited in person from participating programs, and will complete baseline, 6- and 12-month survey follow-ups. Participants were depressed adults (8-item Patient Health Questionnaire ≥10; ≥18 years of age) who provided contact information. Enrolled participants were individually randomised to B-RICH+ or depression QI alone. Primary outcomes are depressive symptoms; secondary outcomes are mental health quality of life, mental wellness and physical health quality of life. Data collection for this study is ongoing.Ethics and disseminationThe current study was approved by the UCLA Institutional Review Board. Study findings will be disseminated through scientific publications and community conferences.Trial registration numberhttps://clinicaltrials.gov/ct2/show/NCT02986126