bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interface Dipole Induced Field‐Effect Passivation for Achieving 21.7% Efficiency and Stable Perovskite Solar Cells
Authors: Wang Fengyou , Zhang Yuhong , Yang Meifang , Han Donglai , Yang Lili , Fan Lin , Sui Yingrui , Sun Yunfei , Liu Xiaoyan , Meng Xiangwei , Yang Jinghai 
Published: October 2020

AbstractOrganolead halide hybrid perovskite solar cells (PSCs) have become a shining star in the renewable devices field due to the sharp growth of power conversion efficiency; however, interfacial recombination and carrier‐extraction losses at heterointerfaces between the perovskite active layer and the carrier transport layers remain the two main obstacles to further improve the power conversion efficiency. Here, novel field‐effect passivation has been successfully induced to effectively suppress the interfacial recombination and improve interfacial charge transfer by incorporating interfacial polarization via inserting a high work function interlayer between perovskite and holes transport layer. The charge dynamics within the device and the mechanism of the field‐effect passivation are elucidated in detail. The unique interfacial dipoles reinforce the built‐in field and prevent the photogenerated charges from recombining, resulting in power conversion efficiency up to 21.7% with negligible hysteresis. Furthermore, the hydrophobic interlayer also suppresses the perovskite decomposition by preventing the moisture penetration, thereby improving the humidity stability of the PSCs (>91% of the initial power conversion efficiency (PCE) after 30 d in 65 ± 5% humidity). Finally, several promising research perspectives based on field‐effect passivation are also suggested for further conversion efficiency improvements and photovoltaic applications.
Highly Efficient Ternary All‐Polymer Solar Cells with Enhanced Stability
Authors: Feng Kui , Wu Ziang , Su Mengyao , Ma Suxiang , Shi Yongqiang , Yang Kun , Wang Yang , Zhang Yujie , Sun Weipeng , Cheng Xing , Huang Limin , Min Jie , Woo Han Young , Guo Xugang 
Published: October 2020

AbstractDeveloping organic solar cells (OSCs) based on a ternary active layer is one of the most effective approaches to maximize light harvesting and improve their photovoltaic performance. However, this strategy meets very limited success in all‐polymer solar cells (all‐PSCs) due to the scarcity of narrow bandgap polymer acceptors and the challenge of morphology optimization. In fact, the power conversion efficiencies (PCEs) of ternary all‐PSCs even lag behind binary all‐PSCs. Herein, highly efficient ternary all‐PSCs are realized based on an ultranarrow bandgap (ultra‐NBG) polymer acceptor DCNBT‐TPC, a medium bandgap polymer donor PTB7‐Th, and a wide bandgap polymer donor PBDB‐T. The optimized ternary all‐PSCs yield an excellent PCE of 12.1% with a remarkable short‐circuit current density of 21.9 mA cm−2. In fact, this PCE is the highest value reported for ternary all‐PSCs and is much higher than those of the corresponding binary all‐PSCs. Moreover, the optimized ternary all‐PSCs show a photostability with ≈68% of the initial PCE retained after 400 h illumination, which is more stable than the binary all‐PSCs. This work demonstrates that the utilization of a ternary all‐polymer system based on ultra‐NBG polymer acceptor blended with compatible polymer donors is an effective strategy to advance the field of all‐PSCs.
3D Coaxial Printing Tough and Elastic Hydrogels for Tissue Engineering Using a Catechol Functionalized Ink System
Authors: Zhou Ying , Yue Zhilian , Chen Zhi , Wallace Gordon 
Published: October 2020

Abstract3D printing is now popular in tissue engineering as it provides a facile route to the fabrication of scaffolds with/without living cells with a predesigned geometry. The properties of the ink constituents are critical for printing structures to meet both mechanical and biological requirements. Despite recent advances in ink development, it remains a challenge to print biopolymer based tough and elastic hydrogels. These hydrogels are in great demand as they can mimic the biomechanics of soft tissues such as skin, muscle, and cartilage. In this study, a catechol functionalized ink system is developed for 3D coaxial printing tough and elastic hydrogels. The ink is based on biopolymers including catechol modified hyaluronic acid (HACA) and alginate. A novel crosslinking strategy is proposed, involving simple ionic crosslinking, catechol mediated crosslinking, and Michael addition that are all induced under mild conditions. The HACA and alginate form a double network with high fracture toughness and elasticity, while proteins such as gelatin can be integrated with the HACA/alginate hydrogel during printing to improve cell interactions. The printed constructs demonstrate high cytocompatibility and support the differentiation of myoblasts into aligned myotubes. The catechol functionalized ink can be further modified to target various applications in soft tissue engineering.
3D Bioprinting of Lignocellulosic Biomaterials
Authors: Shavandi Amin , Hosseini Soraya , Okoro Oseweuba Valentine , Nie Lei , Eghbali Babadi Farahnaz , Melchels Ferry 
Published: October 2020

AbstractThe interest in bioprinting of sustainable biomaterials is rapidly growing, and lignocellulosic biomaterials have a unique role in this development. Lignocellulosic materials are biocompatible and possess tunable mechanical properties, and therefore promising for use in the field of 3D‐printed biomaterials. This review aims to spotlight the recent progress on the application of different lignocellulosic materials (cellulose, hemicellulose, and lignin) from various sources (wood, bacteria, and fungi) in different forms (including nanocrystals and nanofibers in 3D bioprinting). Their crystallinity, leading to water insolubility and the presence of suspended nanostructures, makes these polymers stand out among hydrogel‐forming biomaterials. These unique structures give rise to favorable properties such as high ink viscosity and strength and toughness of the final hydrogel, even when used at low concentrations. In this review, the application of lignocellulosic polymers with other components in inks is reported for 3D bioprinting and identified supercritical CO2 as a potential sterilization method for 3D‐printed cellulosic materials. This review also focuses on the areas of potential development by highlighting the opportunities and unmet challenges such as the need for standardization of the production, biocompatibility, and biodegradability of the cellulosic materials that underscore the direction of future research into the 3D biofabrication of cellulose‐based biomaterials.
Biofunctionalized Liposomes to Monitor Rheumatoid Arthritis Regression Stimulated by Interleukin‐23 Neutralization
Authors: Lima Ana Cláudia , Campos Cláudia F. , Cunha Cristina , Carvalho Agostinho , Reis Rui L. , Ferreira Helena , Neves Nuno M. 
Published: October 2020

AbstractEven after the revolution of rheumatoid arthritis (RA) treatment with biologic agents, this debilitating disease remains a major clinical problem. The outstanding outcomes of the systemic administration of antibodies (Abs) are narrowed by the risk of serious side effects and limited efficacy due to their short half‐life. Interleukin‐23 (IL‐23) is a crucial pro‐inflammatory cytokine involved in inflammation that potently enhances the generation of T‐helper type‐17 (Th17) cells. Hence, in this work, anti‐IL‐23 Abs are immobilized at the surface of liposomes to increase their therapeutic efficacy, being gold nanoparticles (AuNPs) incorporated to allow monitoring the biodistribution of the liposomes after systemic administration as well as due to their anti‐inflammatory and antioxidant effects. A stable monodispersed liposomes’ suspension with around 130 nm is produced and efficiently biofunctionalized with anti‐IL‐23 Abs. IL‐23 capture and neutralization capacity are confirmed using activated macrophages. Biological assays demonstrate their hemocompatibility and cytocompatibility with human articular chondrocytes, macrophages, and endothelial cells. Moreover, the neutralization of IL‐23 by the biofunctionalized liposomes efficiently decreases the production of IL‐17A by peripheral blood mononuclear cells of healthy donors and RA patients who are activated to Th17 differentiation. Therefore, the developed formulation may be a promising strategy to treat RA.
Perovskite‐Derivative Valleytronics
Authors: Liang Jia , Fang Qiyi , Wang Hua , Xu Rui , Jia Shuai , Guan Yuxuan , Ai Qing , Gao Guanhui , Guo Hua , Shen Kaijun , Wen Xiewen , Terlier Tanguy , Wiederrecht Gary P. , Qian Xiaofeng , Zhu Hanyu , Lou Jun 
Published: October 2020

AbstractHalide perovskites are revolutionizing the renewable energy sector owing to their high photovoltaic efficiency, low manufacturing cost, and flexibility. Their remarkable mobility and long carrier lifetime are also valuable for information technology, but fundamental challenges like poor stability under an electric field prevent realistic applications of halide perovskites in electronics. Here, it is discovered that valleytronics is a promising route to leverage the advantages of halide perovskites and derivatives for information storage and processing. The synthesized all‐inorganic lead‐free perovskite derivative, Cs3Bi2I9, exhibits strong light–matter interaction and parity‐dependent optically addressable valley degree of freedom. Robust optical helicity in all odd‐layer‐number crystals with inversion symmetry breaking is observed, indicating excitonic coherence extending well beyond 11 layers. The excellent optical and valley properties of Cs3Bi2I9 arise from the unique parallel bands, according to first principles calculations. This discovery points to new materials design principles for scalable valleytronic devices and demonstrates the promise of perovskite derivatives beyond energy applications.
Novel One‐Step Process for the Production of Levulinic Acid from Furfural over Hierarchical Zeolites in a Microwave Reactor
Authors: Velaga Bharath , Peela Nageswara Rao 
Published: October 2020

AbstractHere, a novel one‐step process is reported for the production of levulinic acid (LA) from furfural over hierarchical zeolites in a microwave reactor. The furfural conversion and product distribution are determined as a function of formalin concentration (CF) in water, catalyst properties, and heating mode. 20 wt% formalin is found to be the critical concentration, above and below which the 5‐hydroxymethylfurfrual and the LA are formed, respectively. The conversion and LA yield over H‐zeolite are higher by 2.3 and 17 times, respectively, as compared to those over Na‐zeolite. The Brønsted to Lewis acid sites ratio is found to be a crucial catalytic parameter to obtain the best activity and LA yield. Under optimal reaction conditions and with the best catalyst, 42% LA yield is obtained at 90% furfural conversion. The humins formed during the process are characterized using Fourier transformed infrared spectroscopy and thermogravimetric analysis. The humins yield, functionality, and decomposition temperatures are varied with both CF and catalyst properties. The reaction pathways and intermediates are also postulated. The integration of the developed process/route with the existing C6 routes allows the utilization of the entire carbohydrate content of the lignocellulosic biomass to produce LA, and consequently, the overall process becomes more economical.
PEGylation of Recombinant Human Deoxyribonuclease I Provides a Long‐Acting Version of the Mucolytic for Patients with Cystic Fibrosis
Authors: Guichard Marie‐Julie , Wilms Tobias , Mahri Sohaib , Patil Harshad P. , Hoton Delphine , Ucakar Bernard , Vanvarenberg Kevin , Cheou Pamela , Beka Mathilde , Marbaix Etienne , Leal Teresinha , Vanbever Rita 
Published: October 2020

AbstractInhalation of recombinant human deoxyribonuclease I (rhDNase) is a gold‐standard therapy in the management of cystic fibrosis (CF). Yet, the rapid elimination of the mucolytic from the lungs requires its daily administration and rhDNase contributes to the high therapy burden of patients. Here, a long‐acting version of rhDNase that is delivered once weekly instead of once daily is presented. Conjugation of rhDNase to a polyethylene glycol (PEG) chain sustains its presence and mucolytic activity within murine lungs for more than 15 days. One single dose of PEGylated rhDNase is as effective as 1 daily dose of unconjugated rhDNase during five days to decrease the DNA content in the lungs of β‐ENaC mice, a model of the CF lung disease. Moreover, once weekly administration of PEGylated rhDNase over four weeks decreases both the DNA content and the neutrophil counts in the lungs of β‐ENaC mice. PEGylated rhDNase is stable to jet nebulization. Finally, multiple high‐dose administrations of PEGylated rhDNase for up to 3 months do not cause any significant pulmonary or systemic toxicity, nor accumulation of the rhDNase or PEG moieties in biological fluids. PEGylation of rhDNase may offer a convenient long‐acting mucolytic to patients with CF.
Modulating Charge Transfer Efficiency of Hematite Photoanode with Hybrid Dual‐Metal–Organic Frameworks for Boosting Photoelectrochemical Water Oxidation
Authors: Wang Keke , Liu Yang , Kawashima Kenta , Yang Xuetao , Yin Xiang , Zhan Faqi , Liu Min , Qiu Xiaoqing , Li Wenzhang , Mullins Charles Buddie , Li Jie 
Published: October 2020

AbstractThe glorious charge transfer efficiency of photoanode is an important factor for efficient photoelectrochemical (PEC) water oxidation. However, it is often limited by slow kinetics of oxygen evolution reaction. Herein, a dual transition metal‐based metal–organic frameworks (MOF) cocatalyst, Fe@Ni–MOF, is introduced into a titanium‐doped hematite (Fe2O3:Ti) photoanode. The combination of Ni and Fe can optimize the filling of 3d orbitals. Moreover, the introduction of Fe donates electrons to Ni in the MOF structure, thus, suppressing the irreversible (long‐life‐time) oxidation of Ni2+ into Ni3+. The resulting Fe@Ni–MOF/Fe2O3:Ti photoanode exhibits ∼threefold enhancement in the photocurrent density at 1.23 V versus the reversible hydrogen electrode. Kinetic analysis of the PEC water oxidation processes indicates that this performance improvement is primarily due to modulating the charge transfer efficiency of hematite photoanode. Further results show that a single transition metal‐based MOF cocatalyst, Ni–MOF, exhibits slow charge transfer in spite of a reduction in surface charge recombination, resulting in a smaller charge transfer efficiency. These findings provide new insights for the development of photoelectrodes decorated with MOFs.
Esophagogastric junction adenocarcinoma shares characteristics with gastric adenocarcinoma: Literature review and retrospective multicenter cohort study
Authors: Imamura Yu , Watanabe Masayuki , Oki Eiji , Morita Masaru , Baba Hideo 
Published: October 2020

AbstractThe incidence of esophagogastric junction (EGJ) adenocarcinoma has been gradually increasing in Asia, just like in Western countries a few decades ago. Despite recent advances in next‐generation sequencing and multimodal treatments, EGJ adenocarcinoma is still an aggressive malignancy with poor outcomes. Clinically, EGJ adenocarcinoma can be separated into Barrett's adenocarcinoma and cardiac adenocarcinoma, with frequent similarities observed. Barrett's adenocarcinoma is likely to be of gastric origin in terms of its premalignant background, risk factors, and stem cell regulators. Recent comprehensive genomic analyses suggest that immunotherapy may be essential for high‐level microsatellite instability (MSI‐H)‐ and Epstein‐Barr virus (EBV)‐associated subtypes, and against the immunosuppressive phenotype in genomically stable (GS) subtypes, in the treatment of EGJ and gastric adenocarcinoma. Although the chromosomal instability (CIN) subtype dominates EGJ adenocarcinoma, there is still a need to investigate the other molecular subtypes and their targets. Because of the distinctive characteristics of tumor location of EGJ adenocarcinoma, we also described the results of a multicenter cohort study of EGJ adenocarcinoma, comparing Siewert type I (distal esophagus), II (cardia of the stomach), and III (subcardia) tumors. We show that type I tumors were frequently accompanied by Barrett's esophagus (78%, P < .0001), with a significantly unfavorable outcome (multivariate EGJ‐cancer‐specific mortality hazard ratio = 1.81, 95% CI, 1.06‐2.97; P = .031). In addition, over half (56%) of these cases experienced disease recurrence in the lymph nodes. Our findings suggest that Barrett's adenocarcinoma may be an aggressive phenotype of EGJ adenocarcinoma due to the potential risk of tumor spread through the complex lympho‐vascular network of the esophagus.
Variants in NAA15 cause pediatric hypertrophic cardiomyopathy
Authors: Ritter Alyssa , Berger Justin H. , Deardorff Matthew , Izumi Kosuke , Lin Kimberly Y. , Medne Livija , Ahrens‐Nicklas Rebecca C. 
Published: October 2020

AbstractThe NatA N‐acetyltransferase complex is important for cotranslational protein modification and regulation of multiple cellular processes. The NatA complex includes the core components of NAA10, the catalytic subunit, and NAA15, the auxiliary component. Both NAA10 and NAA15 have been associated with neurodevelopmental disorders with overlapping clinical features, including variable intellectual disability, dysmorphic facial features, and, less commonly, congenital anomalies such as cleft lip or palate. Cardiac arrhythmias, including long QT syndrome, ventricular tachycardia, and ventricular fibrillation were among the first reported cardiac manifestations in patients with NAA10‐related syndrome. Recently, three individuals with NAA10‐related syndrome have been reported to also have hypertrophic cardiomyopathy (HCM). The general and cardiac phenotypes of NAA15‐related syndrome are not as well described as NAA10‐related syndrome. Congenital heart disease, including ventricular septal defects, and arrhythmias, such as ectopic atrial tachycardia, have been reported in a small proportion of patients with NAA15‐related syndrome. Given the relationship between NAA10 and NAA15, we propose that HCM is also likely to occur in NAA15‐related disorder. We present two patients with pediatric HCM found to have NAA15‐related disorder via exome sequencing, providing the first evidence that variants in NAA15 can cause HCM.
Object, relations: From Alain's corriger selon l'objet1 to Winnicott's transitional object
Authors: Heifetz Aviad 
Published: October 2020

AbstractWe trace the notion of “object” in the thought of Alain and Winnicott. For both of them, our embeddedness within the world is a point of departure. Yet, this does not hinder for them a conceptualization of objectivity, constituted by relations, a conceptualization emanating from the body and spirit at one. But, whereas for Alain, it is a virtue to continuously strive to undo the imposition of our passions on the senseless and essence‐less exteriority, for Winnicott living well necessitates transitional objects and experiences, in which the distinction between “out there” and “in me” is not challenged.
Partial eigenstructure assignment problem for vibration system via feedback control
Authors: Yu Peizhao 
Published: October 2020

AbstractThe partial eigenstructure assignment problem is to replace a small number of eigenvalues and eigenvectors of system while the remaining eigenvalues and corresponding eigenvectors are kept unchanged. The paper studies partial eigenstructure assignment problem for vibration system via acceleration–velocity feedback control. Two new orthogonality relations are established to construct a feedback control law which can solve the proposed partial eigenstructure assignment problem. The solvability condition and parametric expressions of feedback gains are derived for solving this problem. The minimum norm partial eigenstructure assignment problem is further considered by using gradient‐based optimization method. An optimization algorithm is proposed for solving the minimum norm partial eigenstructure assignment problem. Numerical examples are provided to show the effectiveness of the algorithm.
What makes businesses commit to nature conservation?
Authors: Krause Marlen S. , Droste Nils , Matzdorf Bettina 
Published: October 2020

AbstractTo halt the loss of biodiversity and ecosystem services, various actors including companies need to engage, but it is not yet clear what drives voluntary business commitments. We explore leverage points that might increase corporate action for conservation. We apply a structural equation model based on the theory of planned behaviour to analyse data from 618 German companies, collected through an online‐survey in 2019. We show that a favourable attitude, driven by perceived business relevance and benefit prospects, fosters engagement. Perceived difficulties, such as lacking finances and knowledge, hinder the engagement. Customers, employees and the general public are presently the only stakeholder groups that drive corporate conservation engagement. Nevertheless, the expectation levels of virtually all stakeholders were found to be quite low and as such inadequate for the ecological crisis we face. We discuss how political will and goal setting can encourage more widespread business support for the natural environment.
Institutional pressures, environmental management strategy, and organizational performance: The role of environmental management accounting
Authors: Gunarathne A.D. Nuwan , Lee Ki‐Hoon , Hitigala Kaluarachchilage Pubudu K. 
Published: October 2020

AbstractThis study investigates the implementation of environmental management accounting in translating environmental management strategy into organizational performance. Further, the study identifies the influence of institutional pressures on environmental management strategy and environmental management accounting to provide a better description of the impact of the institutional environment on corporate environmental practices. The data were collected from 144 business entities in Sri Lanka using a web‐based survey and analyzed using partial least squares structural equation modeling. We found statistically significant evidence to state that the environmental management strategy is positively associated with the environmental and economic performance of organizations, whereas environmental management accounting mediates this relationship. Further, a firm's institutional environment positively affects both environmental management strategies and environmental management accounting. This study emphasizes that the organizational information systems such as environmental management accounting are useful in providing information on environmental costs and monitoring environmental and financial performance when implementing environmental management strategies in the pursuit of corporate sustainable development.
A cascade of multiple complications hampering a complex high‐risk percutaneous coronary intervention (CHIP‐PCI): When ingenuity overcomes troubles!
Authors: Marchese Alfredo , Tito Antonio , Paparella Domenico , Colombo Antonio 
Published: October 2020

AbstractEven skilled CHIP operators can run into multiple complications. Some are unexpected and not related to the operator, and others are fully preventable by careful procedural choices. If those occur, the knowledge of devices and cognitive skills become lifesaving elements and sudden issues need to be dealt with calmly and efficiently.