bluuebunny/crossref_metadata_2025_split huggingface dataset:
Female Gender Is Associated with a Higher Prevalence of Chronic Neck Pain, Chronic Low Back Pain, and Migraine: Results of the Spanish National Health Survey, 2017
Authors: Palacios-Ceña Domingo , Albaladejo-Vicente Romana , Hernández-Barrera Valentin , Lima-Florencio Lidiane , Fernández-de-las-Peñas Cesar , Jimenez-Garcia Rodrigo , López-de-Andrés Ana , de Miguel-Diez Javier , Perez-Farinos Napoleon 
Published: September 2020

Abstract

Objectives
To assess the prevalence of chronic neck pain (CNP), chronic low back pain (CLBP), and migraine headache (MH) in the Spanish population and to identify sociodemographic and health-related variables associated with CNP, CLBP, and MH.

Design
Observational study.

Setting
Spain.

Subjects
A total of 22,511 persons 18 years of age or older (10,304 males and 12,207 females) who participated in the 2017 Spanish National Health Survey.

Methods
Stratified three-stage sampling was applied. CNP, CLBP, and MH were the dependent variables. The analysis was conducted separately by gender. Sociodemographic features, self-perceived health status, lifestyle habits, comorbidities, and pain features were analyzed by using logistic regression models.

Results
Females reported a higher prevalence of CNP, CLBP, and MH (P &lt; 0.001) than males. For both sexes, anxiety and/or depression and poor self-rated health were associated with a significantly increased prevalence of CNP, CLBP, and MH. For CNP and CLBP, the identified associated factors were older age and limitations to usual activity. For CNP and MH, the most common associated factor was comorbid respiratory disease.

Conclusions
Our study identified several factors associated with CNP, CLBP, and MH in Spanish female and male adults, with potential implications for health care providers.
A cross-sectional population survey of physicians in Alberta, Canada about a novel provincial contact tracing smartphone app
Authors: Jerome D , Pietrosanu M , Dhillon K 
Published: September 2020

Abstract

Background
The Canadian province of Alberta released the ABTraceTogether smartphone app in May 2020 to assist in contact tracing during the SARS-CoV-2 pandemic. Public engagement with this public health tool has been low, limiting the effectiveness of the intervention. This study examines physician knowledge of the app and practice patterns in relation to the app.

Methods
We conducted a cross-sectional self-administered online English language survey of physicians and medical students in Alberta, Canada. The survey link was sent to all registered members of the College of Physicians and Surgeons of Alberta and was distributed by other provincial physician organizations and health zone leaders.

Results
The survey received 317 responses. 96% of participants were aware of the app but only 27% had recommended the app to patients. The most common reason provided for not downloading or recommending the app was that participants had security concerns about the app. 23% of participants indicated they did not believe they had a responsibility to recommend the app to others.

Conclusions
Our study provides insights into participants’ knowledge and beliefs about the ABTraceTogether app. This information may be valuable to public health officials who wish to engage physicians in future public health campaigns.
Crimes Against Morality: Unintended Consequences of Criminalizing Sex Work*
Authors: Cameron Lisa , Seager Jennifer , Shah Manisha 
Published: September 2020

Abstract
We examine the impact of criminalizing sex work, exploiting an event in which local officials unexpectedly criminalized sex work in one district in East Java, Indonesia, but not in neighboring districts. We collect data from female sex workers and their clients before and after the change. We find that criminalization increases sexually transmitted infections among female sex workers by 58 percent, measured by biological tests. This is driven by decreased condom access and use. We also find evidence that criminalization decreases earnings among women who left sex work due to criminalization and decreases their ability to meet their children’s school expenses while increasing the likelihood that children begin working to supplement household income. Although criminalization has the potential to improve population STI outcomes if the market shrinks permanently, we show that five years postcriminalization the market has rebounded and the probability of STI transmission in the general population is likely to have increased.
More is Less: Publicizing Information and Market Feedback*
Authors: Bird Andrew , Karolyi Stephen A , Ruchti Thomas G , Truong Phong 
Published: September 2020

Abstract
We study whether and how publicizing internal information affects the value of financial markets to the real economy. By publicizing corporate filings, the Securities and Exchange Commission’s EDGAR (Electronic Data Gathering, Analysis, and Retrieval) web platform reduces the cost of acquiring internal information for outsiders and so makes it relatively less attractive to gather external information. We find that the staggered introduction of EDGAR reduced the sensitivity of firm investment to prices, consistent with prices being less informative to managers due to the crowding out of external information gathering. This crowding out effect is stronger when outsiders’ incentives for gathering information are stronger and for firms that rely more on external information. Our findings suggest that policies designed to “level the playing field” by publicizing internal information can have significant unintended consequences by reducing the informativeness of prices for real decisions.
PREHISTORY OF THE CZECH RADON PROGRAM
Authors: Thomas Josef Jiří 
Published: September 2020

Abstract
In the Czech Republic, the program managing high radon levels in dwellings has existed for nearly 30 years. Although the recent history of radiation protection from naturally radioactive gas is quite well known, prior radon management is less understood. This article describes the history of natural radioactivity and its management from the Middle Ages, showing that Czech countries have a much longer and abundant history related to natural radioactivity.
The Law on the Books Versus the Law in Action: Muslim Women in Polygamous Marriages under the Jewish State
Authors: Aburabia Rawia 
Published: September 2020

Abstract
Based on empirical evidence from the Shari’a court in Beersheba of the ratification of customary polygamous marriages, the article examines the complexity of legal recognition of second marriages and the structural conditions under which polygamy is possible in the plural legal orders that exist in Israel. Although polygamy is criminally prohibited by the state of Israel, this prohibition is not enforced among the Bedouin in Israel, where 18.5 percent of Bedouin households are polygamous. This article demonstrates how these conditions perpetuate patriarchal norms among the Bedouin under the auspices of colonial legal structures.
Phylogenomics of Parasitic and Nonparasitic Lice (Insecta: Psocodea): Combining Sequence Data and Exploring Compositional Bias Solutions in Next Generation Data Sets
Authors: de Moya Robert S , Yoshizawa Kazunori , Walden Kimberly K O , Sweet Andrew D , Dietrich Christopher H , Kevin P Johnson 
Published: September 2020

AbstractThe insect order Psocodea is a diverse lineage comprising both parasitic (Phthiraptera) and nonparasitic members (Psocoptera). The extreme age and ecological diversity of the group may be associated with major genomic changes, such as base compositional biases expected to affect phylogenetic inference. Divergent morphology between parasitic and nonparasitic members has also obscured the origins of parasitism within the order. We conducted a phylogenomic analysis on the order Psocodea utilizing both transcriptome and genome sequencing to obtain a data set of 2370 orthologous genes. All phylogenomic analyses, including both concatenated and coalescent methods suggest a single origin of parasitism within the order Psocodea, resolving conflicting results from previous studies. This phylogeny allows us to propose a stable ordinal level classification scheme that retains significant taxonomic names present in historical scientific literature and reflects the evolution of the group as a whole. A dating analysis, with internal nodes calibrated by fossil evidence, suggests an origin of parasitism that predates the K-Pg boundary. Nucleotide compositional biases are detected in third and first codon positions and result in the anomalous placement of the Amphientometae as sister to Psocomorpha when all nucleotide sites are analyzed. Likelihood-mapping and quartet sampling methods demonstrate that base compositional biases can also have an effect on quartet-based methods.[Illumina; Phthiraptera; Psocoptera; quartet sampling; recoding methods.]
The virome from a collection of endomycorrhizal fungi reveals new viral taxa with unprecedented genome organization
Authors: Sutela Suvi , Forgia Marco , Vainio Eeva J , Chiapello Marco , Daghino Stefania , Vallino Marta , Martino Elena , Girlanda Mariangela , Perotto Silvia , Turina Massimo 
Published: September 2020

Abstract
Mutualistic plant-associated fungi are recognized as important drivers in plant evolution, diversity, and health. The discovery that mycoviruses can take part and play important roles in symbiotic tripartite interactions has prompted us to study the viromes associated with a collection of ericoid and orchid mycorrhizal (ERM and ORM, respectively) fungi. Our study, based on high-throughput sequencing of transcriptomes (RNAseq) from fungal isolates grown in axenic cultures, revealed in both ERM and ORM fungi the presence of new mycoviruses closely related to already classified virus taxa, but also new viruses that expand the boundaries of characterized RNA virus diversity to previously undescribed evolutionary trajectories. In ERM fungi, we provide first evidence of a bipartite virus, distantly related to narnaviruses, that splits the RNA-dependent RNA polymerase (RdRP) palm domain into two distinct proteins, encoded by each of the two segments. Furthermore, in one isolate of the ORM fungus Tulasnella spp. we detected a 12 kb genomic fragment coding for an RdRP with features of bunyavirus-like RdRPs. However, this 12 kb genomic RNA has the unique features, for Bunyavirales members, of being tri-cistronic and carrying ORFs for the putative RdRP and putative nucleocapsid in ambisense orientation on the same genomic RNA. Finally, a number of ORM fungal isolates harbored a group of ambisense bicistronic viruses with a genomic size of around 5 kb, where we could identify a putative RdRP palm domain that has some features of plus strand RNA viruses; these new viruses may represent a new lineage in the Riboviria, as they could not be reliably assigned to any of the branches in the recently derived monophyletic tree that includes most viruses with an RNA genome.
Anatomy, taxonomy and phylogeny of the Eocene guitarfishes from the Bolca Lagerstätten, Italy, provide new insights into the relationships of the Rhinopristiformes (Elasmobranchii: Batomorphii)
Authors: Marramà Giuseppe , Carnevale Giorgio , Naylor Gavin J P , Varese Massimo , Giusberti Luca , Kriwet Jürgen 
Published: September 2020

Abstract
We here re-evaluate the skeletal anatomy and the systematic position of the two Eocene guitarfish species represented by almost complete and articulated material from the Konservat-Lagerstätten of Bolca in Italy. The analyses of morphometric, skeletal and dental features of ‘Rhinobatos’ dezignii and ‘R.’ primaevus allow them to be excluded from the living guitarfish genus Rhinobatos and assigned to the new genera †Pseudorhinobatos gen. nov. and †Eorhinobatos gen. nov., respectively. The placement of these new genera within the rhinopristiform family Rhinobatidae is based on the possession of a series of morphological features (e.g. pectoral fins fused to head forming a wedge-shaped pectoral disc; rostral cartilage extending to the tip of the snout; nuchal cartilages and horn-like processes of nasal capsules absent; teeth with Rhinobatos-like morphology displaying smooth enameloid, central uvula and two lateral uvulae) that unambiguously exclude their assignment to any other rhinopristiform family. A new morphology-based phylogenetic analysis that includes the two new fossil genera, described herein, provides novel insights into the relationships of the Batoidea and recovers the Rhinopristiformes as a paraphyletic group. This indicates that the monophyly of extant taxa could be the result of the extinction of crucial taxa.
What Influences Choice of Continuing Medical Education Modalities and Providers? A National Survey of U.S. Physicians, Nurse Practitioners, and Physician Assistants
Authors: O’Brien Pott Maureen , Blanshan Anissa S. , Huneke Kelly M. , Baasch Thomas Barbara L. , Cook David A. 
Published: September 2020

Purpose
To explore what influences clinicians in selecting continuing medical education (CME) activities in the United States.

Method
In August 2018, the authors conducted an Internet-based national survey, sampling 100 respondents from each of 5 groups: family medicine physicians, internal medicine and hospitalist physicians, medicine specialist physicians, nurse practitioners, and physician assistants. In total, 1,895 clinicians were invited and 500 (26%) responded. Questions addressed the selection and anticipated use of CME delivery modalities and perceived characteristics of specific CME providers. Response formats used best–worst scaling or 5-point ordinal response options.

Results
The factors identified as most important in selecting CME activities were topic (best–worst scaling net positivity 0.54), quality of content (0.51), availability of CME credit (0.43), and clinical practice focus (0.41), while referral frequency (−0.57) ranked lowest. The activities that the respondents anticipated using most in the future were live (mean 3.8 [1 = not likely, 5 = very likely]), online (mean 3.5), point-of-care (mean 3.5), and print-based (mean 3.5) activities. For online CME, the features of greatest appeal were that learning could be done when clinicians had time (mean 4.4), at their own pace (mean 4.2), and at lower cost (mean 4.2). For live CME, the features of greatest appeal were that the subject was best taught using this modality (mean 4.0), or the activity was located in a destination spot (mean 4.0) or a regional location (mean 3.9). When rating specific CME providers, most academic institutions received relatively high ratings for research focus and clinical practice focus, whereas commercial providers had slightly higher ratings for ease of access. Responses were generally similar across clinician types and age groups.

Conclusions
Physicians, nurse practitioners, and physician assistants are interested in using a variety of CME delivery modalities. Appealing features of online and live CME were different.
Early diagnosis and population prevention of coronavirus disease 2019
Authors: Su Ying-Ying , Zhang Shi-Yin , Li Ting-Dong , Xia Ning-Shao 
Published: September 2020

Purpose of review
To discuss the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by nucleic acid and antibody testing as well as its contribution to mitigating the spread of coronavirus disease 2019.

Recent findings
Nucleic acid testing (NAT) is the firstly developed and most widely used diagnostic technique for SARS-CoV-2 infection. However, the sensitivity of SARS-CoV-2 RNA NAT assays is always unsatisfactory, mainly due to insufficient viral RNA in samples, especially when upper respiratory samples were used. Compared with NAT assays, serological tests are more convenient and less dependent on the quality of sample collection. But the sensitivity of antibody assays varies largely to test samples collected at different time after onset of symptoms. The diagnostic sensitivity can be significantly improved by combination of RNA and antibody testing. Due to the lack of effective drugs and vaccines, population prevention results mainly from timely triage and quarantine of SARS-CoV-2 infected individuals. Thus, extensive testing with NAT and antibody assays simultaneously is very important to constrain coronavirus disease 2019 epidemic.

Summary
Viral RNA testing combining with serological testing could improve the early diagnosis of SARS-CoV-2 infection, which has great value for clinical practice and public health.
Standardizing abortion education: what medical schools can learn from residency programs
Authors: Burns Roshan M. , Shaw Kate A. 
Published: September 2020

Purpose of review
With over 50 million abortions annually and 25% of pregnancies ending in abortion worldwide, abortion is one of the most common medical procedures. Yet abortion-related topics are glaringly absent from medical school curricula in the USA with half of medical schools including no formal training or only a single lecture. We explore abortion education in US medical schools and Obstetrics and Gynecology (Ob/Gyn) residency programs. Specifically, we review efforts to improve and standardize this training.

Recent findings
Despite documented interest in both learning and in the benefits of early exposure, medical students face a lack of educational opportunities in abortion care. Meanwhile, Ob/Gyn residency has standardized requirements for abortion care, greatly improving training and education, despite persistent challenges in universal compliance with these standards.

Summary
Education in abortion care is crucially important in fostering and training future abortion providers, thereby ensuring and expanding access to safe abortion. The improvements made by standardizing abortion education in Ob/Gyn residency should encourage similar efforts in medical school in order to increase earlier and wider exposure to future physicians of all specialties. On a national level, standardizing exams for medical students by which to evaluate their understanding of abortion care would hold schools accountable for medical student education.
Pulmonary hypertension associated with left-sided heart failure
Authors: Adler Joana , Gerhardt Felix , Wissmüller Max , Adler Christoph , Baldus Stephan , Rosenkranz Stephan 
Published: September 2020

Purpose of review
Pulmonary hypertension is a common phenomenon in heart failure patients that is highly relevant for morbidity and outcome. Although postcapillary in nature, the pathophysiology of pulmonary hypertension in patients with heart failure with reduced or preserved ejection fraction is complex, and decisions about management strategies remain challenging.

Recent findings
Recently, the hemodynamic definitions and subclassification of postcapillary pulmonary hypertension have been revisited. The distinction between isolated postcapillary pulmonary hypertension (IpcPH) and combined post and precapillary pulmonary hypertension (CpcPH) and their definition are essential. Novel data on the prognostic impact of hemodynamic variables and right ventricular function highlight the importance of cardiopulmonary interaction in patients with left-sided heart failure (LHF). Furthermore, the impact of management strategies including medical therapy, remote hemodynamic monitoring, and interventional approaches on hemodynamics and outcome has recently been investigated. Here, we critically review recent developments and future considerations in this field, and highlight distinct treatment strategies targeting the underlying left heart condition, the pulmonary circulation, and/or impaired right ventricular function.

Summary
Detailed hemodynamic characterization and proper phenotyping are essential for prognostication and the management of patients with pulmonary hypertension associated with LHF, both in clinical practice and when addressing research questions.
Keratoconus Prevalence in Families: A French Study
Authors: Lapeyre Gabrielle , Fournie Pierre , Vernet Raphaël , Roseng Stéphanie , Malecaze François , Bouzigon Emmanuelle , Touboul David 
Published: September 2020

Purpose:
To assess the keratoconus (KC) prevalence among first-degree relatives of affected subjects.

Methods:
We performed large epidemiological, prospective, and observational cohort, which took place in the French KC National Reference Centre, in Bordeaux. We studied data from 94 unrelated patients with KC and at least 2 first-degree relatives assessable. Each subject had a thorough ocular examination including visual acuity, refraction, slitlamp biomicroscopy, indirect ophthalmoscopy, keratometry, corneal topography and tomographer (Topographic Modeling System; Tomey Corporation, Japan; and Galilei G4, Ziemer, Switzerland, respectively), pachymetry, and biomechanical properties of cornea (Ocular Response Analyzer; Reichert, Depew, NY). Additional data were collected about atopy, smoking, and eye-rubbing habits. KC prevalence, multivariate analysis, and familial correlation analysis have been studied.

Results:
Of the 221 relatives, 9.05% (n = 20) had clinically manifest KC, and 15.4% (n = 31) had subclinical KC. The prevalence of KC was estimated equal to 0.14 [95% confidence interval (CI), 0.07–0.22] among parents, 0.03 (95% CI, 0–0.10) among offspring, and 0.10 (95% CI, 0.04–0.20) among siblings. In multivariable analysis, age and eye-rubbing were associated with an increased risk of KC. The familial correlation of KC among probands' first-degree relatives was estimated at 0.55 among parents, 0.29 among offspring, and 0.49 among siblings.

Conclusions:
Being a first-degree relative of a subject with KC remains a risk factor for developing KC. This should be taken into account especially when screening for KC in pediatric patients, for refractive surgery candidates, and for patients being evaluated for cataract surgery.
General risks of harm with cannabinoids, cannabis, and cannabis-based medicine possibly relevant to patients receiving these for pain management: an overview of systematic reviews
Authors: Mohiuddin Mohammed , Blyth Fiona M. , Degenhardt Louisa , Di Forti Marta , Eccleston Christopher , Haroutounian Simon , Moore Andrew , Rice Andrew S.C. , Wallace Mark , Park Rex , Gilron Ian 
Published: September 2020

Abstract
The growing demand for improved pain treatments together with expanding legalization of, and access to, cannabinoids, cannabis, and cannabis-based medicines has intensified the focus on risk–benefit considerations in pain management. Given limited harms data from analgesic clinical trials, we conducted an overview of systematic reviews focused on all harms possibly relevant to patients receiving cannabinoids for pain management. This PROSPERO-registered, PRISMA-compliant systematic overview identified 79 reviews, encompassing over 2200 individual reports about psychiatric and psychosocial harms, cognitive/behavioral effects, motor vehicle accidents, cardiovascular, respiratory, cancer-related, maternal/fetal, and general harms. Reviews, and their included studies, were of variable quality. Available evidence suggests variable associations between cannabis exposure (ranging from monthly to daily use based largely on self-report) and psychosis, motor vehicle accidents, respiratory problems, and other harms. Most evidence comes from settings other than that of pain management (eg, nonmedicinal and experimental) but does signal a need for caution and more robust harms evaluation in future studies. Given partial overlap between patients receiving cannabinoids for pain management and individuals using cannabinoids for other reasons, lessons from the crisis of oversupply and overuse of opioids in some parts of the world emphasize the need to broadly consider harms evidence from real-world settings. The advancement of research on cannabinoid harms will serve to guide optimal approaches to the use of cannabinoids for pain management. In the meantime, this evidence should be carefully examined when making risk–benefit considerations about the use of cannabinoids, cannabis, and cannabis-based medicine for chronic pain.