bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on the shear movement law of overlying strata by slice mining
Authors: Fu Junhui , Wen Guangcai , Sun Haitao , Yang Xuelin 
Published: March 2020

AbstractBased on the analysis of shear movement characteristics of overlying strata under mining effect, a quantitative calculation model for shear displacement in the along‐strike and down‐dip directions of the overlying strata is established. The shear displacement at any point on the interface of overlying strata in composite rock beam under slice mining is analyzed. The evolution law of shear displacement and deformation of the overlying strata with the advancement of working face was inverted by physical simulation test. The results show that the shear movement of the overlying strata is characterized by a repeated pattern of "increase → decrease →increase → decrease.” The shear displacement of the overlying strata increases gradually after slice mining. The shear displacement of the overlying strata is in the shape of “W” after the lower seam mining, and the maximum shear displacement of the overlying strata by the lower seam mining is 1.67 times of that of the overlying strata after the upper seam mining. Field test of shear movement of the overlying strata was conducted on the panel 4308 of Chengzhuang coal mine. The results show that the shear displacement of the overlying strata above the coal seam increases with the burial depth. And the shear displacement of the overlying strata movement after mining has "time‐delay" effect. The larger the depth of the measuring point is, the larger value of the along‐strike shear displacement is. The breakage of the key strata of the overlying strata will cause the shear displacement of the overlying strata to increase rapidly. And there is a demarcation depth (127.98 m) for the shear displacement of the overlying strata. The shear movement of the overlying strata above the dividing point is not obvious, while the shear movement of the overlying strata below the dividing point is in the shape of "S" (amplitude of 50 mm). When the working face advanced beyond the test well, the overlying strata would experience multiple shear movement. When the working face advanced 34‐100 m ahead of the surface test well, the overlying strata experienced the most severe shear displacement. When the working face advanced to 74 m away from the surface test well, the shear displacement of the overlying strata between 10# (depth of 192.01 m) and 16# (depth of 300.07 m) is larger than that at the upper position, and down‐dip shear displacement is the most severe(about 315 mm). The shear displacement of the overlying strata is coincident with the along‐strike shear displacement, and the down‐dip shear displacement is smaller than the along‐strike shear displacement. This research provides theoretical guidance for the design of shale gas or coalbed methane surface wells and coal mine shaft under slice mining.
Dual‐phase‐lag model on magneto‐thermoelastic rotating medium with voids and diffusion under the effect of initial stress and gravity
Authors: Abo‐Dahab S. M. , Abd‐Alla Abdelmooty M. 
Published: March 2020

AbstractIn this paper, the propagation of harmonic plane waves is considered in a generalized thermoelastic medium with diffusion and voids in the presence of initial stress, magnetic field, rotation, and gravity in the context of thermoelastic models; classical, Lord Shulman, Green Lindsay as well as dual‐phase‐lag models. We applied the boundary conditions in the physical domain using the normal mode method technique on the surface to obtain the displacements, stresses, temperature, diffusion concentration, and the volume fraction field. Influence of initial stress, magnetic field, rotation, and gravity on temperature, stresses, concentration of diffusion, and the volume fraction is observed through a numerical example. The results obtained will be compared in the presence and absence of the new considered variables, also with the previous results obtained by the others and displayed graphically.
Follow‐up of late‐onset Pompe disease patients with muscle magnetic resonance imaging reveals increase in fat replacement in skeletal muscles
Authors: Nuñez‐Peralta Claudia , Alonso‐Pérez Jorge , Llauger Jaume , Segovia Sonia , Montesinos Paula , Belmonte Izaskun , Pedrosa Irene , Montiel Elena , Alonso‐Jiménez Alicia , Sánchez‐González Javier , Martínez‐Noguera Antonio , Illa Isabel , Díaz‐Manera Jordi 
Published: March 2020

AbstractBackgroundLate‐onset Pompe disease (LOPD) is a genetic disorder characterized by progressive degeneration of the skeletal muscles produced by a deficiency of the enzyme acid alpha‐glucosidase. Enzymatic replacement therapy with recombinant human alpha‐glucosidase seems to reduce the progression of the disease; although at the moment, it is not completely clear to what extent. Quantitative muscle magnetic resonance imaging (qMRI) is a good biomarker for the follow‐up of fat replacement in neuromuscular disorders. The aim of this study was to describe the changes observed in fat replacement in skeletal muscles using qMRI in a cohort of LOPD patients followed prospectively.MethodsA total of 36 LOPD patients were seen once every year for 4 years. qMRI, several muscle function tests, spirometry, activities of daily living scales, and quality‐of‐life scales were performed on each visit. Muscle MRI consisted of two‐point Dixon studies of the trunk and thigh muscles. Computer analysis of the images provided the percentage of muscle degenerated and replaced by fat in every muscle (known as fat fraction). Longitudinal analysis of the measures was performed using linear mixed models applying the Greenhouse–Geisser test.ResultsWe detected a statistically significant and continuous increase in mean thigh fat fraction both in treated (+5.8% in 3 years) and in pre‐symptomatic patients (+2.6% in 3years) (Greenhouse–Geisser p < 0.05). As an average, fat fraction increased by 1.9% per year in treated patients, compared with 0.8% in pre‐symptomatic patients. Fat fraction significantly increased in every muscle of the thighs. We observed a significant correlation between changes observed in fat fraction in qMRI and changes observed in the results of the muscle function tests performed. Moreover, we identified that muscle performance and mean thigh fat fraction at baseline visit were independent parameters influencing fat fraction progression over 4 years (analysis of covariance, p < 0.05).ConclusionsOur study identifies that skeletal muscle fat fraction continues to increase in patients with LOPD despite the treatment with enzymatic replacement therapy. These results suggest that the process of muscle degeneration is not stopped by the treatment and could impact muscle function over the years. Hereby, we show that fat fraction along with muscle function tests can be considered a good outcome measures for clinical trials in LOPD patients.
Physiological and psychological stress in pregnant women with quiescent inflammatory bowel disease: A pilot study using salivary biomarkers
Authors: Khil Jennifer , Picardo Sherman , Seow Cynthia H. , Leung Yvette , Metcalfe Amy , Afshar Elnaz E. , Sharifi Nastaran , Campbell Tavis , Letourneau Nicole , Dewey Deborah , Giesbrecht Gerald F. ,   the APrON Study Team
Published: March 2020

AbstractBackgroundPregnant women with inflammatory bowel disease (IBD) are more likely than the general pregnant population to experience adverse maternofetal outcomes, especially if the disease is active at the time of conception and during pregnancy. Elevated stress is often seen in patients with chronic diseases and could account for these outcomes. Salivary cortisol and alpha‐amylase (sAA) are novel biomarkers of stress, reflecting the hypothalamic‐pituitary‐adrenal (HPA) axis and sympathetic nervous system, respectively. Our aim in this pilot study was to assess stress differences between pregnant women with inactive IBD and matched controls using psychometric questionnaires and salivary biomarker measures.MethodsThirteen pregnant women with quiescent IBD (6 Crohn's disease, 7 ulcerative colitis) were matched (1:3) to 39 expectant mothers without IBD by parity and gestational age. Participants completed several psychometric questionnaires assessing stress, and salivary cortisol and sAA were collected as objective biomarkers of stress during pregnancy.ResultsPregnant women with quiescent IBD did not demonstrate significant differences on any psychometric measures of stress or salivary biomarker measures when compared with controls (all P > 0.05). Pregnant women with quiescent IBD demonstrated similar cortisol and sAA awakening responses (both P > 0.05) and total levels of cortisol and sAA production (both P > 0.05) when compared with controls.ConclusionsPregnant women with well‐controlled IBD do not experience demonstrable differences in psychological stress or dysregulation of salivary stress biomarkers when compared with non‐IBD controls. The effect of chronic disease may be evaluated in future studies by including a comparative group of pregnant women with active IBD.
A novel nonsense mutation in the L1CAM gene responsible for X‐linked congenital hydrocephalus
Authors: Guo Dewei , Shi Yuting , Jian Wenyan , Fu Yimei , Yang Hui , Guo Manhui , Yong Wenjing , Chen Gang , Deng Huan , Qin Yan , Liao Weihua , Yao Ruojin 
Published: March 2020

AbstractBackgroundCongenital hydrocephalus is a descriptive diagnosis of symptoms, that are present for numerous reasons, including chromosomal disorders, genetic mutations, intrauterine infection and hemorrhage, amongst other factors. Mutation of L1CAM gene is the most frequent cause of congenital hydrocephalus, contributing to approximately 30% of X‐linked congenital hydrocephalus.MethodsIn the present study, we used whole‐exome sequencing and Sanger sequencing to investigate an aborted male fetus present with severe congenital hydrocephalus at 24 weeks of gestation, whose mother had a history of two previous voluntary terminations of pregnancies as a result of hydrocephalus. Magnetic resonance imaging, an autopsy and electron microscopy were performed and the phenotypic changes were described.ResultsWhole‐exome sequencing in the fetus, as well as variant segregation analysis, revealed a novel maternally derived hemizygous nonsense mutation (c.2865G>A; p. Y955*) in exon 21 of the L1CAM gene (NM_000425.4). Severe hydrocephalus was observed along with marked dilatation of lateral ventricles. An electron micrograph of the surface of lateral ventricle walls revealed a lack of ependymal cilia.ConclusionThe present study suggests that L1CAM mutation screening should be considered for a male fetus with isolated hydrocephalus, especially with a family history, which could facilitate prenatal diagnosis in a subsequent pregnancy.
Application of urease inhibitor improves protein composition and bread‐baking quality of urea fertilized winter wheat
Authors: Rekowski Azin , Wimmer Monika A. , Hitzmann Bernd , Hermannseder Bernhard , Hahn Heike , Zörb Christian 
Published: March 2020

AbstractBackground: Nitrogen losses is an economic problem for wheat production and a high risk to the environment. Therefore, improved N fertilizer management is a key to increasing the N efficiency and minimizing N losses. To increase N efficiency, enhanced fertilizers such as urea combined with urease inhibitor can be used.Aims: The aim of present study was to evaluate the effects of different N forms on grain storage protein subunits in winter wheat and to examine whether the observed changes correlate with parameters of baking quality.Methods: The investigation was performed over two consecutive years at two locations in Germany. Protein subunits were analyzed by SDS‐PAGE.Results: Protein concentrations were similarly increased after fertilization with ammonium nitrate and urea + urease inhibitor. Analysis of the individual storage protein fractions indicated that both fertilizers specifically enhanced ω‐gliadins and HMW glutenins, but the effect was more pronounced in the ammonium nitrate treatment. Application of urea + urease inhibitor had greater influence on the protein composition and resulted in higher specific baking volume as well as the best fresh keeping ability, in comparison with urea treatment.Conclusion: Considering that the urea + urease inhibitor treatment resulted in almost comparable improvements of NUE and baking quality, with the additional benefit of reduced N losses in combination with easy handling, urea + urease inhibitor can be recommended as a viable alternative to both urea alone and ammonium nitrate treatments. This opens up an opportunity for the reduction of N loss in wheat production when use of urea is preferred.
Industrial clusters in the developing economies: Insights from the Iranian carpet industry
Authors: Saadatyar Fahime Sadat , Al‐Tabbaa Omar , Dagnino Giovanni Battista , Vazife Zahra 
Published: March 2020

AbstractIndustrial clusters are perceived as potential drivers of small and medium‐sized enterprises development and efficient policy instruments to lead national and regional innovation and growth. However, these clusters in developing economies are typically placed in complex environments that impose a mix of serious challenges that adversely affect their overall performance. Therefore, this study aims to analyze the nature of these challenges and understand their dynamics using a case study of a carpet industry cluster in Iran. Using multiple sources of evidence, the study reveals two distinct, yet interrelated, levels of challenges: micro and macro. Under each level, a number of key dimensions were identified and theoretically linked which helped to conceptualize the structure of these challenges and model their dynamics.
Simple compensation method for improved half‐pulse excitation profile with rephasing gradient
Authors: Latta Peter , Starčuk Zenon , Kojan Martin , Gruwel Marco L. H. , Tomanek Boguslaw , Trattnig Siegfried , Juras Vladimir 
Published: March 2020

PurposeTo improve the slice profile quality obtained by RF half‐pulse excitation for 2D‐UTE applications.MethodsThe overall first‐order and zero‐order phase errors along the slice‐selection direction were obtained with the help of an optimization task to minimize the out‐of‐slice signal contamination from the calibration 1‐dimenisonal (1D) profile data. The time‐phase‐error evolution was approximated from the k‐space readout data, which were acquired primarily for correction of the readout trajectories during data regridding to the rectilinear grids. The correction of the slice profile was achieved by rephasing gradient pulses applied immediately after the end of excitation. The total prescan calibration typically took less than 2 minutes.ResultsThe improved image quality using the proposed calibration method was demonstrated both on phantoms and on ankle images obtained from healthy volunteers. It was demonstrated that calibration can be performed either as a separate water phantom measurement or directly as a prescan procedure.ConclusionThe slice‐profile distortion from the half‐pulse excitation could substantially affect the overall fidelity of 2D‐UTE images. The presented experiments proved that the image quality could be substantially increased by application of the proposed slice‐correction method.
Interrupted time series analysis to assess changes in prescription filling around conception and implications for exposure misclassification
Authors: Cohen Jacqueline M. , Selmer Randi , Furu Kari , Karlstad Øystein 
Published: March 2020

AbstractPurposeMedication exposures in pregnancy are often defined by one or more prescription fills. Harmful effects could be underestimated if rapid discontinuation of use after pregnancy recognition is common. We used conception, a critical biological period, as an intervention in a novel application of interrupted time series analysis (ITSA).MethodsAmong 645 049 pregnancies from the Medical Birth Registry (2005‐2015) linked to the Norwegian Prescription Database, we modeled the total number of prescription fills in the 12 weeks before and after estimated conception date with ITSA. We examined psychostimulants, antidepressants, antipsychotics, and antiepileptics (AEDs; separated by use for epilepsy or other indications). We used relative measures (%) to compare model coefficients. We also compared number of pregnancies defined as exposed when the earliest fill considered was 30 days before the last menstrual period (LMP −30 days), LMP, or estimated conception date (LMP +14 days).ResultsWe observed a sudden decline in prescription fills from 2 weeks after conception and decreasing fills thereafter for psychostimulants, antidepressants, AEDs for other indications, and antipsychotics excluding incident users. Fills for AEDs for epilepsy did not fall after conception. Only 77% of pregnancies with fills for psychostimulants from LMP and 58% with fills from LMP −30 days had fills from conception. Similar figures for AEDs for epilepsy were 99% and 96%.ConclusionsThis application shows that ITSA can help researchers understand rapid changes in patient behavior around conception that have consequences for exposure misclassification in pregnancy drug safety studies. ITSA results can help pharmacoepidemiologists guide study exposure definitions.
Cancer worry and empathy moderate the effect of a survivorship‐focused intervention on quality of life
Authors: Parker Patricia A. , Banerjee Smita C. , Matasar Matthew J. , Bylund Carma L. , Schofield Elizabeth , Li Yuelin , Jacobsen Paul B. , Astrow Alan B. , Leventhal Howard , Horwitz Steven , Kissane David 
Published: March 2020

AbstractObjectiveThis study examined the impact of a survivorship planning consultation (SPC) for patients with Hodgkin's lymphoma and diffuses large B‐cell lymphoma on quality of life (QOL). We specifically assessed two potential moderators, cancer worry and perceived empathy, of the intervention effects on QOL.MethodsThis cluster randomized, four‐site trial examined the efficacy of a SPC; physicians received communication skills training and applied these skills in a survivorship‐focused office visit using a care plan vs a control arm in which physicians were trained to and subsequently provided a time‐controlled, manualized wellness rehabilitation consultation focused only on discussion of healthy nutrition and exercise. We examined the effect of the intervention on patients' QOL and examined potential moderators—cancer worry and perceived physician empathy.ResultsForty‐two physicians and 198 patients participated. There was no main effect of the intervention on any of the QOL dimensions (ps > 0.10). However, cancer worry was a significant moderator of the effects of the intervention on three QOL domains (physical P = .04; social P = .04; spiritual P = .01) and perceived empathy was a significant moderator of QOL (physical P = .004; psychological P = .04; social P = .01). Specifically, the beneficial effects of the intervention were more pronounced among patients who initially reported higher levels of cancer worry and lower levels of physician empathy.ConclusionsThis study identified two factors, perceived empathy and cancer worry, that were found to impact the QOL of patients who participated in this communication‐based survivorship intervention.
Suicide attempts in patients with head and neck cancer in Taiwan
Authors: Sun Li‐Min , Lin Cheng‐Li , Shen Wei‐Chih , Kao Chia‐Hung 
Published: March 2020

AbstractObjectiveWe examined the risk of suicide attempts in patients with head and neck cancer (HNC) in comparison with that in the general population and in patients of other cancers (including all other cancers rather than HNC).MethodsThe definition of suicide attempt here is that an attempt of suicide with or without completed suicide. This retrospective cohort study consisted of 66 931 cases of HNC and individual without HNC from the general population assigned to the control group. Cox's proportion hazard regression analysis was conducted to compare the subsequent suicide attempt risk between patients with HNC and the control group.ResultsThe suicide attempt rate for HNC and control groups were 7.44 and 1.98 per 10 000 person‐year, respectively. A more than three‐fold higher risk of suicide attempts was observed in the HNC group than in the control group (adjusted hazard ratio [HR]: 3.72; 95% confidence intervals: 2.85, 4.88). Patients of HNC also had a significantly 1.9‐fold higher risk of suicide attempt than patients with other cancers. Subsequent stratified analyses revealed a significantly elevated risk of suicide attempts across every cancer anatomic subsite and almost all categories of various demographics, but the risk was limited to male patients and patients with no comorbidity. The suicide attempt rate was the highest among patients with oropharyngeal cancer, and chemotherapy was associated with an elevated risk of suicide attempt.ConclusionsPatients with HNC are vulnerable to an increased risk of suicide attempts than the general population and patients with other cancers.
Inference of the lifetime performance index with power Rayleigh distribution based on progressive first‐failure–censored data
Authors: Mahmoud Mohamed Abdul Wahab , Kilany Neveen Mohamed , El‐Refai Lobna Hisham 
Published: March 2020

AbstractOne of the modern statistical methods is assessing quality performance of product. The performance of a process in the manufacturing and services industry is assessed to examine the level of product quality. The product performance is measured using the lifetime performance index
, where
is a lower specification limit. In this paper, the maximum likelihood estimation (MLE) of
for the power Rayleigh distribution is derived based on progressive first‐failure–censored sample on the condition of known
is calculated. The hypothesis testing procedure is applied for assessing whether the lifetime of products meets the required level. Finally, real‐life data of the number of revolutions before failure of a ball bearing in endurance life time test are used to illustrate the proposed procedure.
Rapid bulk density measurement using mobile device photogrammetry
Authors: Whiting Michael , Salley Shawn W. , James Darren K. , Karl Jason W. , Brungard Colby W. 
Published: March 2020

AbstractSoil bulk density (Db), the ratio of soil solid mass to bulk soil volume, is an important but difficult soil property to measure. Existing methods are either expensive, time consuming, or destructive to the sample. The goal of this research was to investigate the utility of photogrammetry for measuring Db. Photogrammetry is the determination of shape and volume from multiple overlapping photos. Photos of soil peds placed on a 3D‐printed turntable were obtained using two mobile devices. Photogrammetry‐measured volume and Db were compared with volume and Db measured using the clod and 3D laser‐scanning methods. No significant differences between Db measured by any method were found. No statistical difference between cameras types was found. We conclude that photogrammetry is a useful method for measuring Db. Measuring Db using photogrammetry was much easier than the other methods and was less expensive and faster than 3D laser scanning.
Diagrammatic state sums for 2D pin-minus TQFTs
Authors: Turzillo Alex 
Published: March 2020

AbstractThe two dimensional state sum models of Barrett and Tavares are extended to unoriented spacetimes. The input to the construction is an algebraic structure dubbed half twist algebras, a class of examples of which is real separable superalgebras with a continuous parameter. The construction generates pin-minus TQFTs, including the root invertible theory with partition function the Arf-Brown-Kervaire invariant. Decomposability, the stacking law, and Morita invariance of the construction are discussed.