bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Kualitas Produk Terhadap Kepuasan, Reputasi Merek Dan Loyalitas Konsumen Jamu Tolak Angin Pt. Sido Muncul
Authors: Hermawan Budi 
Published: December 2020

One of the key factor that PT Sido Muncul concerns about its Jamu Tolak Angin is the customer loyalty. The increase number of loyal customers can be considered as the success of the company’s product amidst the competition. This research is conducted to find out whether the product’s quality influences the customer loyalty through customer satisfaction and brand reputation of the PT Sido Muncul’s Jamu Tolak Angin brand. This research is conducted to retest the model proposed by Fred Selnes (1993), by using the Structural Equation Model (SEM). The sample of this research is 200 persons, collected by judgment sampling. The result of this research shows that customer loyalty is influenced by product quality, customer satisfaction, and brand reputation. Product quality influences customer loyalty through customer satisfaction and brand reputation. The model’s test of this research shows Chi-Square=65.81 (P=0.00026), RMSEA=0.071, GFI=0.94, dan AGFI=0.90. Product quality influences customer loyalty through customer satisfaction and brand reputation by 0.26 and it influences customer loyalty through brand reputation by 0.46. This research shows that good quality product will lead to the increase of customer loyalty and brand reputation of the PT Sido Muncul’s Jamu Tolak Angin brand. Loyal customers are directly influenced by PT Sido Muncul’s Jamu brand, while customer satisfaction doesn’t directly influence customer loyalty. When choosing which jamu product to consume, the customers don’t necessarily choose the product based on the satisfaction of past use but on the brand reputation. Customers think that the jamu brand that has good reputation is suitable for continuous use. This is because customers view jamu as traditional medicine, so the selection should be based on those products who have reliable brand reputation. This result shows that the PT Sido Muncul’s Jamu Tolak Angin brand reputation that has been formed may strengthen the product quality’s influence on creating customer loyalty.
POTENSI PENGIMPLEMENTASIAN PARIWISATA HALAL DI KABUPATEN SLEMAN BERDASARKAN KEBUTUHAN RELIJIUS WISATAWAN MUSLIM
Authors: Muniroh Misbahul , Herianingrum Sri 
Published: December 2020

ABSTRAKDalam mewujudkan visi Indonesia sebagai pusat ekonomi syariah terkemuka di dunia, pemerintah berfokus pada pengembangan beberapa industri yang terbagi ke dalam beberapa klaster dimana salah satunya adalah pariwisata halal. Penelitian ini bertujuan untuk menganalisis potensi yang dimiliki kabupaten Sleman untuk menerapkan pariwisata halal ditinjau dari kebutuhan relijius wisatawan Muslim yakni makanan dan minuman halal, fasilitas ibadah, ketersediaan kamar kecil berbasis air, dan keamanan saat berwisata, serta ditinjau dari regulasi yang ada terkait pelaksanaan pariwisata halal. Metode penelitian yang digunakan ialah kualitatif deskriptif dengan teknik pengumpulan data berupa wawancara, dokumentasi, dan observasi tidak langsung. Hasil penelitian ini menunjukkan bahwa kondisi kepariwisataan kabupaten Sleman saat ini mendukung penerapan pariwisata halal karena makanan dan minuman halal, fasilitas ibadah, dan kamar kecil berbasis air dapat ditemukan dengan mudah, serta keamanan saat berwisata yang dirasakan wisatawan baik domestik maupun mancanegara. Walaupun demikian, belum ada regulasi yang mengatur tentang pelaksanaan pariwisata halal di kabupaten Sleman mengingat belum ada induk hukum yang memayunginya.Kata Kunci: Potensi Pariwisata, Pariwisata Halal, Kebutuhan Relijius Wisatawan Muslim, Kabupaten Sleman ABSTRACTIn order to actualize Indonesian vision as the center of Islamic economy in the world, the government focuses on the development of several industries which are divided into several clusters including halal tourism. This study aims to analyze Sleman regency’s potential to implement halal tourism in terms of religious needs of Muslim traveler such as halal food and beverage, worship facility, water-based toilet availability, and safety during visitation, and also in terms of regulation about halal tourism implementation. The research method used in this study is descriptive qualitative whereas data collection technique used are interview, documentation, and indirect observation. The result shows that current tourism condition in Sleman regency supports the implementation of halal tourism since halal food and beverage, worship facility, and water-based toilet are available and easily found, and also travelers felt safe during their visit in Sleman regency. Nevertheless, there is no regulation about halal tourism implementation in Sleman regency yet as there is no higher regulation above.Keyword: Tourism Potential, Halal Tourism, Religious Needs of Muslim Traveler, Sleman Regency
PENGARUH RETURN SAHAM, RISIKO SAHAM, PERTUMBUHAN EKONOMI, BAGI HASIL DEPOSITO, UKURAN PERUSAHAAN DAN PENDAPATAN PEMBAGIAN SURPLUS UNDERWRITTING TERHADAP PROPORSI INVESTASI DANA PERUSAHAAN ASURANSI JIWA SYARIAH PADA SAHAM SYARIAH DI INDONESIA
Authors: Ulandari Ulandari , Rusgianto Sulistya 
Published: December 2020

ABSTRAKiPenelitian ini imemiliki itujuan untuk imenganalisis lebih dalam mengenai ifaktor-faktor yang imempengaruhi iperusahaan iasuransi ijiwa isyariah, dalam mengambil ikebijakan ibesaran proporsi iinvestasi dana ipersahaan pada isaham syariah. Hal ini dilakukan untuk imemberikan sebuah iwawasan secara iteoritis kepada perusahaan dalam mengambil ikebijakan mengenai iproporsi iinvestasi dana perusahaan. Fokus penelitian ini di Indonesia dengan pendekatan kuantitatif. Data diperoleh dari 10 perusahaan asuransi jiwa syariah yang beroperasi dari 2012 hingga 2018. Metode yang digunakan regresi data panel dengan random effect model. Hasil ipenelitian ini adalah ireturn saham, risiko saham, dan ibagi ihasil deposito secara statistik iberpengaruh signifikan terhadap proporsi investasi dana perusahaan asuransi jiwa syariah pada saham syariah. Sedangkan ipertumbuhan ekonomi, iukuran iperusahaan dan pendapatan pembagian surplus underwriting secara statistik tidak iberpengaruh terhadap proporsi investasi dana iperusahaan iasuransi ijiwa syariah pada isaham syariah. Kata Kunci: Proporsi Investasi, Return Saham, Risiko Saham, Pertumbuhan Ekonomi, Bagi Hasil Deposito, Ukuran Perusahaan dan Pendapatan Pembagian Surplus Underwritting ABSTRACTThis study aimed to analyze more deeply the factors that influence sharia life insurance companies in making a policy of the proportion of investment in company funds in sharia stocks. This study to provide a theoretical insight into the company in making policy regarding the proportion of the company's investment funds to adapt it to the circumstances experienced by the company. Focus of research in Indonesia with quantitative approach which data collected from 10 sharia life insurance companys financial statements among 2012 until 2018. Method of research uses regression panel data with random effect model. The results of this study were stock returns, stock risk, and profit-sharing on deposits had a significant effect on the proportion of investment in Islamic life insurance company funds in sharia stocks. Meanwhile, economic growth, company size, and revenue sharing of the underwriting surplus do not affect the proportion of sharia life insurance company investment in sharia stocks. Keywords: Investment Proportion, Stock Returns, Stock Risk, Economic Growth, Deposit Profit Sharing, Company Size and Income Share of the Underwriting Surplus
Charge order textures induced by non-linear lattice coupling in a half-doped manganite
Authors: Baggari Ismail El , Baek David , Zachman Michael , Lu Di , Hikita Yasuyuki , Hwang Harold , Nowadnick Elizabeth , Kourkoutis Lena 
Published: December 2020

Abstract
The self-organization of strongly interacting electrons into superlattice structures underlies the properties of many quantum materials. How these electrons arrange within the superlattice dictates what symmetries are broken and what ground states are stabilized. Here we show that cryogenic scanning transmission electron microscopy enables direct mapping of local symmetries and order at the intra-unit-cell level in the model charge-ordered system Nd1/2Sr1/2MnO3. In addition to imaging the prototypical site-centered charge order, we discover the nanoscale coexistence of an exotic intermediate state which mixes site and bond order and breaks inversion symmetry. We further show that nonlinear coupling of distinct lattice modes controls the selection between competing ground states. The results demonstrate the importance of lattice coupling for understanding and manipulating the character of electronic self-organization and highlight a novel method for probing local order in a broad range of strongly correlated systems.
Challenging the uncertainty of COVID-19 in rural community based medical education for family medicine: A thematic analysis
Authors: Ohta Ryuichi , Ryu Yoshinori , Sano Chiaki 
Published: December 2020

Abstract
BackgroundCommunity based medical education (CBME) enriches undergraduate and postgraduate students’ perspectives, especially in rural settings. For the continuity of rural CBME in Japan, the present disruption caused by the coronavirus must be overcome to drive CBME and educate future family physicians adequately in rural community hospitals. In this study, we examine the challenges faced by and solutions for sustainable CBME in community hospitals during the COVID-19 pandemic.MethodsA qualitative study was performed with CBME stakeholders in a community hospital. First, direct observation was performed by the first author. Through this method, field and reflection notes were taken by observing and interviewing the dean, medical teachers, nurses, medical students, a medical clerk, and rural citizens in the hospital and its surrounding rural communities from April 1 to September 30, 2020. Interviews were recorded, and their contents were transcribed verbatim. The authors analyzed the transcriptions using on a thematic analysis.ResultsOverall, 31 pages of field and reflection notes were collated through direct observation and used for analysis. Five physicians, eight nurses, one clerk, fourteen medical trainees, and three rural citizens were interviewed. Through the thematic analysis, three themes emerged: the uncertainty of COVID-19, an overwhelming fear within medical institutions, and motivation and determination to continue providing CBME.ConclusionRural CBME for family medicine should be continued for the sustainability of rural medicine, even during the COVID-19 pandemic. The end of the pandemic cannot be foreseen, and CBME in rural areas should be continued to serve its true purpose by carefully considering precautions and through continuous dialogue between stakeholders and medical educators.
Impact of the COVID-19 Pandemic on Health-Related Quality of Life and Anxiety in Pediatric Hematology/Oncology Patients: A Single Egyptian Center Experience
Authors: Hassan Eman , Rizk Dalia Nagui , Aly Nourhan Moustafa , Chazli Yasmine El 
Published: December 2020

Abstract
Background: Since the World Health Organization declared coronavirus disease 2019 (COVID-19) pandemic on March 11, 2020, the tremendous strain on ill-prepared healthcare services affected the management of patients suffering from various comorbidities and added to the psychological burden. The study aimed to assess the health-related quality of life (HRQoL) of pediatric Hematology/Oncology patients during the COVID-19 pandemic as a reflection of the quality of health care services and to assess anxiety levels and its impact on HRQoL. Methods: a cross-sectional study of 292 Egyptian children between 2.5 - 13 years with chronic hematological/oncological disorders categorized as bleeding/coagulation disorders, transfusion-dependent patients, and patients receiving chemotherapy. Validated Arabic versions of Pediatric Quality of Life Inventory 4.0 Generic Core Scale and Spence Children's Anxiety Scale were used for assessment of HRQoL and anxiety, respectively. Results: the mean age was 8.72 ± 3.66 years, 52.4% were males and 65.4% were transfusion-dependent patients. Almost 60% of children were aware of the pandemic and 60.3% had blood transfusion difficulties. Males had significantly lower anxiety levels than females (p < 0.001), and transfusion-dependent patients also had significantly lower anxiety levels than patients receiving chemotherapy (p < 0.001). Children who were aware of the COVID-19 pandemic had lower anxiety levels than those who were not (p = 0.006), while those suffering from fewer clinic days had higher anxiety levels (p = 0.02). Several factors have been shown to affect the HRQoL in the three patients’ categories and anxiety significantly reduced the three HRQoL domains (p < 0.001). The overall emotional functioning score was better than the physical and social aspects. Conclusion: This study highlights the effect of the COVID-19 pandemic on the anxiety level and hence the HRQoL of chronic hematological/oncological pediatric patients as a crucial step in guiding policies and interventions to maintain their psychological wellbeing.
Corpus Callosum Volumes in Toddlers With Autism Spectrum Disorders: Gender-Associated Differences and Clinical Correlations
Authors: Zhang Yun , Qin Bin , Wang Longlun , Zhang Ke , Song Cui , Chen Jie , Cai Jinhua , Li Tingyu 
Published: December 2020

Abstract
Background: Gender differences in clinical features is a prominent feature of autism spectrum disorder (ASD), and the corpus callosum (CC) is the largest commissural tract connecting the left and right hemispheres associated with autism symptoms. This study aimed to analyze the relationship between gender-associated clinical features and CC size in children aged 2-4 years.Methods: A prospective study of 100 children aged 2-4 years, including 50 cases with ASD (ASD group) and 50 cases with typically developing (TD group) who were matched with equivalent samples of ASD, were recruited with assessments of demographic data (gender, age, and body mass index [BMI]), clinical features (full-scale/verbal/performance IQ, ADOS, and ADI-R), and CC size measured by Structural Magnetic Resonance Imaging. SPSS version 22 was used to analyze the data.Results: The mid-posterior CC (MPCC), anterior-middle CC (AMCC), and total CC (TCC) volumes in ASD were higher than that in TD, and the significance these sub-regions volumes between ASD-Females and ASD-Males was existed in ASD group (all P < 0.05). Analogously, the mean of verbal IQ score in ASD-Males was significantly higher than in ASD-Females, but the scores of ADOS communication (AC) and ADOS total (AT) were lower in ASD-Males (all P < 0.05). AC and AT scores were significantly and positively related to MPCC, AMCC and TCC volumes (all P < 0.05), but verbal IQ score was significantly and negatively associated with MPCC, AMCC and TCC volumes (all P < 0.05). In ASD-Males and -Females, both AC and AT scores increase with the change of MPCC, AMCC and TCC volumes, but VIQ decline.Conclusion: The language ability, including communication and verbal IQ, of ASD aged 2-4 years old has gender differences, which may be related to the CC size, especially the MPCC and AMCC.
Sensitivity of Dirac fermion and Weyl fermion by the Energy Conservation Law of Lenz
Authors: Oh Teresa , Li Xiangjiang 
Published: December 2020

Abstract
The law of Lenz as an energy conservation law between the electric field and the magnetic field allows the charge current and spin current generated by matters and antimatters to be symmetrical with each other. Thus, there is a Lenz plane of symmetry to the electromagnet energy. Phase isolators are charged current by electrons and spin current by spin. The charge current is Weyl fermion, and the spin current is Dirac fermion. The charge current and spin current are characterized by balancing each other, and the fermion, which has both particles and carriers, is Majorana fermion. The reaction was investigated when phase insulators in the state of Dirac fermion and Weyl fermion were exposed to CO2 gas. Although the sensitivity of the phase isolator has decreased as Weyl fermion makes spin current in the gas environment, the sensitivity of the phase isolator has increased as Dirac fermion makes charge current in the gas environment. The spin current of the Dirac fermion has a super current characteristic with a resistance of zero and quantum tunneling phenomenon has occurred. According to Lenz's energy conservation law, the electron sensor has an advantage of the phase insulator in the state of Dirac fermion, where the charge current increases.
Long-Term Predialysis Systolic Blood Pressure Variability and Intradialytic Cardiac Hemodynamics in Hemodialysis Patients
Authors: Yang Jingjuan , Huang Jian , Yu Biying , Zhang Qian , Zhang Shanshan , Wu Longlong , Luo Lin , Li Lizhu , Li Li , Han Fei , Wilcox: Christopher S. , Lai En Yin , Yang Yi 
Published: December 2020

Abstract
The association in hemodialysis patients between long-term predialysis blood pressure variability and intradialytic cardiac hemodynamics was assessed prospectively in 1070 patients receiving maintenance hemodialysis for more than 3 months. Predialysis blood pressure variability was assessed over 1-year intervals. Outcomes included factors were intradialytic hypotension and change in rate-pressure product. The final cohort’s mean age was 59 years, and 57% were males. Greater predialysis systolic blood pressure variability was associated with an increased risk of intradialytic hypotension (adjusted hazard ratio, 1.097; 95% confidence intervals 1.055 to 1.140) and change in rate-pressure product (adjusted hazard ratio, 1.213; 95% confidence intervals 1.163 to 1.265). Results were similar when blood pressure variability was stratified by baseline systolic blood pressure. Factors associated with higher systolic blood pressure variability were older age, female sex, longer duration of dialysis, and diagnosis of diabetic nephropathy, and lower levels of serum albumin. In conclusion, greater predialysis systolic blood pressure variability among hemodialysis patients was associated with greater intradialytic cardiac hemodynamic instability. Strategies to reduce blood pressure variability might be beneficial for hemodialysis patients.
How Do N Addition Affect Soil Fungal Community Assembly: Short- Versus Long-term Effects?
Authors: He Jinhong , Jiao Shuo , Tan Xiangping , Wei Hui , Ma Xiaomin , Nie Yanxia , Liu Juxiu , Lu Xiankai , Mo Jiangming , Shen Weijun 
Published: December 2020

Abstract
Background: Soil fungi play critical roles in ecosystem processes and are sensitive to global changes. Elevated atmospheric nitrogen (N) deposition has been well documented to impact on fungal diversity and community composition, but how fungal community assembly respond to short- and long-term simulative N deposition remains poorly understood. Here, we carried out two field experiments to investigate the soil fungal community variations and assembly processes under short- (2 years) versus long-term (13 years) exogenous nitrogen addition (100 kg N ha-1 yr-1) in a N-rich tropical forest of China. Results: We observed that short-term N addition significantly increased fungal taxonomic and phylogenetic α-diversity, and shifted fungal community composition with significant increases in the relative abundance of Ascomycota and saprotrophic fungi, and decreases in the relative abundance of Basidiomycota and ectomycorrhizal (EcM) fungi. However, unremarkable effects were found under long-term N addition. The variations of fungal α-diversity, community composition, the relative abundance of major phyla, genera and functional guilds were mainly correlated with soil pH and the concentrations of NO3--N, and these correlations were much stronger under short- than long-term N addition. The results of null, neutral community models and the 39 normalized stochasticity ratio (NST) index consistently revealed that stochastic processes played predominant roles in the assembly of soil fungal community under N addition in the tropical forest, and that the relative contributions of stochastic processes were higher at short-term site. Furthermore, both short- and long-term N addition slightly loosened the co-occurrence networks of the fungal community. Conclusions: These findings highlighted that the responses of fungal community structure to N addition were duration-dependent, i.e., the fungal community was sensitive to the short-term N addition but become acclimatized to long-term N enrichment.
Hyaluronic Acid Nanoparticles-encapsulated Bacterial Genotoxin for Targeted Therapy of Radioresistant Prostate Cancer
Authors: Chen Yu-An , Lai Yi-Ru , Wu Hui-Yu , Lo Yen-Ju , Chang Yu-Fang , Hung Chiu-Lien , Lin Chun-Jung , Lo U-Ging , Lin Ho , Hsieh Jer-Tsong , Chiu Cheng-Hsun , Lin Yu-Hsin , Lai Chih-Ho 
Published: December 2020

Abstract
Background: Prostate cancer (PCa) is one of the most commonly diagnosed cancers in men and usually becomes refractory because of recurrence and metastasis. CD44, a transmembrane glycoprotein, serves as a receptor for hyaluronic acid (HA) and has been found to be abundantly expressed in cancer stem cells (CSCs) that often exhibit a radioresistant phenotype. Cytolethal distending toxin subunit B (CdtB), produced by Campylobacter jejuni, is a genotoxin acts as a type I deoxyribonuclease (DNase I), which is responsible for creating DNA double-strand breaks (DSBs). Nanoparticles loaded with antitumor drugs and specific ligands that recognize cancerous cell receptors are promising methods to overcome the therapeutic challenges. Results: In this study, PCa cells with DOC-2/DAB2 interactive protein (DAB2IP) knockdown were employed to imitate the CSC with radioresistant phenotype. We further prepared HA-decorated nanoparticles-encapsulated CdtB (HA-CdtB-NPs) and investigated the targeted therapeutic activity in radioresistant PCa cells. Our results showed that HA-CdtB-NPs sensitized radioresistant PCa cells by enhancing DSB and causing G2/M cell-cycle arrest, without affecting the normal prostate epithelial cells. These results demonstrate that HA-CdtB-NPs possess maximum target-specificity and delivery efficiency of CdtB into the nucleus, and enhance the effect of radiation in radioresistant PCa cells. Conclusions: These findings indicate that HA-loaded CdtB nanoparticles exert target-specificity accompanied with radiomimetic activity, which can be developed as an effective agent for overcoming radioresistance in PCa.