bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unmet nursing care needs on medical and surgical wards: A scoping review of patients’ perspectives
Authors: Bagnasco Annamaria , Dasso Nicoletta , Rossi Silvia , Galanti Carolina , Varone Gloria , Catania Gianluca , Zanini Milko , Aleo Giuseppe , Watson Roger , Hayter Mark , Sasso Loredana 
Published: November 2019

AbstractAims and objectivesTo review and synthesise research studies on surgical and medical inpatients’ perceptions on unmet nursing care needs.BackgroundMissed nursing care is a growing phenomenon that has been shown to adversely affect care outcomes—mainly in adult medical and surgical care settings. However, to date the aggregated and synthesised evidence of missed care comes from research that measures perceptions on missed care in surgical and medical settings from nurses, but not from the patients.DesignScoping review.MethodsIn September 2018, three databases were searched: MEDLINE/PubMed, CINAHL and SCOPUS and papers were selected using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. Inclusion criteria were as follows: primary studies; published in peer‐reviewed journals; in English or Italian; and regarding routine care provided to adult inpatients. Quality appraisal and a thematic analysis were conducted.ResultsOf the 1541 abstracts initially identified, 44 papers were included. Five themes emerged: “communication,” “self‐management, autonomy and education,” “personal sphere,” “essential physical care” and “emotional and psychological care.” The majority of the unmet needs were related to the “personal sphere” and “emotional and psychological care.” These unmet needs were not identified in previous literature on nurses’ perspectives of missed care. Also, physical care deficits like oral hygiene were identified.ConclusionIt is important to take into account patients’ perspectives. The themes focusing on patients’ personal sphere, and emotional and psychological care, underline how patients need nurses to pay more attention to their cultural background, consider the person as a whole and for nursing care to be holistic and respectful of patients’ dignity.Relevance to Clinical PracticeThis study intends to raise awareness amongst nurses and policymakers about the importance of addressing missed nursing care and unmet patients’ needs in adult medical or surgical inpatient settings to ensure high‐quality care and patient satisfaction.
The self‐assessment of clinical competence and the need for further training: A cross‐sectional survey of advanced practice nursing students
Authors: Taylor Ingrid , Bing‐Jonsson Pia , Wangensteen Sigrid , Finnbakk Elisabeth , Sandvik Leiv , McCormack Brendan , Fagerström Lisbeth 
Published: November 2019

AbstractAims and objectives(a) To describe and analyse advanced practice nursing students' self‐assessment of their clinical competence and need for further training and (b) to analyse the possible predictive variables in their self‐assessment.BackgroundThe self‐assessment of clinical competence in nursing education is important for identifying professional development and educational needs to improve patient care.DesignA cross‐sectional survey following STROBE guidelines was used.MethodsNinety‐nine students from three universities/university colleges in Norway participated in the study, and data were collected using a revised version of the Professional Nurse Self‐Assessment Scale II. Descriptive, correlation and regression analyses were performed.ResultsThe students gave the highest self‐assessment ratings for their clinical competence in taking full responsibility and for their need for further training in medication effects and interactions. Although the students gave themselves low ratings for the use of electronic devices, they assessed their need for further training in this area as average. Clinical work experience as a registered nurse and previous higher education level were not significant predictors of clinical competence nor the need for further training.ConclusionThe findings indicate that self‐assessment is appropriate for students in advanced practice nursing programmes. This study implies that programmes in advanced practice nursing need to familiarise students with the possibilities of information technology. It questions the entry requirement that stipulates that prospective students must have several years of clinical work experience as registered nurses before entering advanced practice nursing programmes. These programmes need to communicate that competencies other than direct clinical practice are also needed for students' future roles.Relevance to clinical practiceThe study contributes to the exploration of how students self‐assess own clinical competence and need for further training in advanced practice nursing programmes. Further research should evaluate the development of clinical competence.
Complications following frenotomy for ankyloglossia: A 24‐month prospective New Zealand Paediatric Surveillance Unit study
Authors: Hale Matthew , Mills Nikki , Edmonds Liza , Dawes Patrick , Dickson Nigel , Barker David , Wheeler Benjamin J 
Published: November 2019

AimTo investigate the incidence and characteristics of complications arising from frenotomy for ankyloglossia (tongue‐tie) in New Zealand.MethodsProspective surveillance among hospital‐based paediatricians of complications arising from frenotomy for ankyloglossia to children <1 year old was conducted by the New Zealand Paediatric Surveillance Unit for 24 months, from August 2016 to July 2018, inclusive.ResultsA total of 16 cases of complications arising from frenotomy were reported. The overall average annual incidence rate was 13.9/100 000. Geographic variation was noted with a peak of 85.6/100 000 in one region. Complications reported: poor feeding (44%), respiratory events (25%), pain (19%), bleeding (19%) and weight loss (19%). Three children (19%) also had delayed diagnosis of an underlying medical condition initially overlooked in favour of treating their ankyloglossia, this has not previously been reported. The majority (75%) of cases required admission to hospital. Treatments given included supplementary feeds (44%), surgical intervention (25%), breastfeeding support (19%), analgesia (13%) and blood products (13%). A total of 25% of children had one or more frenotomies; 50% were treated for two or more of: ‘anterior’ ankyloglossia, ‘posterior’ ankyloglossia or ‘lip tie’; 50% had their frenotomies performed out of the hospital. Dentists were the most common performing practitioner (31%).ConclusionsFrenotomy rates in New Zealand are unknown. Poor feeding, pain, bleeding, weight loss and delayed diagnosis of an alternative underlying medical condition are important complications that require hospital assessment and admission. Practitioners and parents/families need to be aware of these possibilities. Centralised guidelines with access to specialist second opinions should be developed.
The role of Helicobacter pylori DnaA domain I in orisome assembly on a bipartite origin of chromosome replication
Authors: Nowaczyk‐Cieszewska Malgorzata , Zyla‐Uklejewicz Dorota , Noszka Mateusz , Jaworski Pawel , Mielke Thorsten , Zawilak-Pawlik Anna Magdalena 
Published: November 2019

AbstractThe main roles of the DnaA protein are to bind the origin of chromosome replication (oriC), to unwind DNA and to provide a hub for the step‐wise assembly of a replisome. DnaA is composed of four domains, with each playing a distinct functional role in the orisome assembly. Out of the four domains, the role of domain I is the least understood and appears to be the most species‐specific. To better characterise Helicobacter pylori DnaA domain I, we have constructed a series of DnaA variants and studied their interactions with H. pylori bipartite oriC. We show that domain I is responsible for the stabilisation and organisation of DnaA‐oriC complexes and provides cooperativity in DnaA–DNA interactions. Domain I mediates cross‐interactions between oriC subcomplexes, which indicates that domain I is important for long‐distance DnaA interactions and is essential for orisosme assembly on bipartite origins. HobA, which interacts with domain I, increases the DnaA binding to bipartite oriC; however, it does not stimulate but rather inhibits DNA unwinding. This suggests that HobA helps DnaA to bind oriC, but an unknown factor triggers DNA unwinding. Together, our results indicate that domain I self‐interaction is important for the DnaA assembly on bipartite H. pylori oriC.
The reverse gyrase TopR1 is responsible for the homeostatic control of DNA supercoiling in the hyperthermophilic archaeon Sulfolobus solfataricus
Authors: Couturier Mohea , Gadelle Danièle , Forterre Patrick , Nadal Marc , Garnier Florence 
Published: November 2019

AbstractMaintaining an appropriate DNA topology with DNA‐based processes (DNA replication, transcription and recombination) is crucial for all three domains of life. In bacteria, the homeostatic regulation for controlling DNA supercoiling relies on antagonistic activities of two DNA topoisomerases, TopoI and gyrase. In hyperthermophilic crenarchaea, the presence of such a regulatory system is suggested as two DNA topoisomerases, TopoVI and reverse gyrase, catalyze antagonistic activities. To test this hypothesis, we estimated and compared the number of the TopoVI with that of the two reverse gyrases, TopR1 and TopR2, in Sulfolobus solfataricus cells maintained either at 80 or at 88°C, or reciprocally shifted from one temperature to the other. From the three DNA topoisomerases, TopR1 is the only one exhibiting significant quantitative variations in response to the up‐ and down‐shifts. In addition, the corresponding intrinsic activities of these three DNA topoisomerases were tested in vitro at both temperatures. Although temperature modulates the three DNA topoisomerases activities, TopR1 is the sole topoisomerase able to function at high temperature. Altogether, results presented in this study demonstrate, for the first time, that the DNA topological state of a crenarchaeon is regulated via a homeostatic control, which is mainly mediated by the fine‐tuning of TopR1.
What Love Is Not: Lessons from Martin Luther King, Jr.
Authors: Lloyd Vincent 
Published: November 2019

AbstractFocusing on the concept and practice of love sheds light on Martin Luther King, Jr.’s negative political theology. King was fundamentally concerned with what love is not, and it is this negation that colors his political vision. I do not take King’s political theology to be either primarily derivative of American liberal Protestantism or primarily derivative of folk African American religion, or of some syncretism of these. Rather, I take King to be participating in a tradition of negative theology that pairs the critique of idolatry with attention outward and inward, to the marginalized and to spiritual life.
A SHMT1 variant decreases the risk of nonsyndromic cleft lip with or without cleft palate in Chile
Authors: Salamanca Carlos , González‐Hormazábal Patricio , Recabarren Andrea S. , Recabarren Pamela A. , Pantoja Roberto , Leiva Noemi , Pardo Rosa , Suazo José 
Published: November 2019

AbstractObjectiveTo assess the association between polymorphic variants from SHMT1 and MTHFS genes, involved in the cytoplasmic futile folate cycle, and the risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in the Chilean population.Subjects and MethodsIn a sample of 139 Chilean NSCL/P cases and 278 controls, we obtained the genotypes for nine variants of SHMT1 and MTHFS and the association between them and the phenotype was evaluated using odds ratios (OR) in additive (allele), dominant, and recessive models.ResultsAfter correction for multiple comparisons, only the variant rs1979277 (G > A; p.Leu474Phe) from SHMT1 showed a significant and protective effect for additive (OR 0.60; 95% CI 0.42–0.86; p = .0054, q = 0.0488) and dominant models (OR 0.48; 95% CI 0.29–0.75; p = .0009; q = 0.0081). Our bioinformatic prediction plus functional evidence from previous reports demonstrate that the A allele for this missense variant decreases the enzymatic activity.ConclusionsOwing to the rs1979277 A allele, which reduces the cytoplasmic SHMT activity and has a higher frequency in controls than in NSCL/P cases, we hypothesized that a low enzyme activity may increase the cytoplasmic concentration of folates and, therefore, explain the protective role against OFCs.
Effect of anemia on muscle oxygen saturation during submaximal exercise
Authors: Crispin Philip 
Published: November 2019

BACKGROUNDObjective measures to assess the need for transfusion in chronic anemia are lacking. Near‐infrared spectroscopy may be used, but there is wide variability. Assessment of muscle oxygen saturation (SmO2) during exercise could be used to measure the impact of anemia on performance of everyday activities.STUDY DESIGN AND METHODSHematology patients and controls were recruited to undertake a 6‐minute walk test (6MWT) and a 20‐second isometric handgrip exercise. Muscle oxygen saturation in the exercising muscles was measured before and during exercise. Changes in saturation during exercise were described. Correlations between identified variables, hemoglobin concentration, and 6MWT distance were undertaken. The effect of transfusion was assessed on a transfused subset.RESULTSThere were 95 sets of exercises conducted in 74 participants. Baseline SmO2 correlated with hemoglobin concentration and negatively with 6MWT distance. Paradoxically, a higher hemoglobin was associated with a greater SmO2 fall during the 6MWT, likely due to greater consumption from improved walk distances. The fall in SmO2 was independent of hemoglobin during isometric contraction, although levels were lower during contraction due to the lower starting SmO2. There was a longer time to peak SmO2 during recovery following isometric exercise in anemia. There were 17 paired tests following a change in hemoglobin, with SmO2 not predicting improvement in those who had improved exercise capacity.CONCLUSIONWhile baseline SmO2 correlated with hemoglobin concentration, the correlation was not strong enough to predict transfusion requirements. Recovery after isometric forearm contraction correlated with hemoglobin and warrants further investigation.
Geometric Design and Analysis of Novel Asymmetrical Rotors for Roots Vacuum Pumps
Authors: Wang Jun , Yang Shuran , Sha Rundong , Li Hongxin , Xu Chao 
Published: November 2019

Abstract
Roots rotors dramatically determine the performance of Roots vacuum pumps. In order to develop new rotors with higher performance, a pair of novel asymmetrical rotors or eccentric involute rotors were proposed based on the conventional symmetrical involute rotors. Profiles of one rotor consist of four eccentric involutes and four circular arcs; profiles of the other rotor consist of four conjugate curves of eccentric involutes and four circular arcs. A model of the proposed asymmetrical rotors was established, and effects of geometric parameters on the area-utilizing ratio of rotors were analyzed. The study results show that the proposed asymmetrical rotors have more number of independent geometric parameters than the conventional rotors of Roots vacuum pumps, so that the asymmetrical rotors are superior to the conventional rotors in terms of design flexibility. The contents of this study can be applied in the design of Roots vacuum pumps.
Investigation on an Adaptive Method for Tonal Vibration Suppression
Authors: Xie Xiling , Ren Mingke , Zhang Zhiyi 
Published: November 2019

Abstract
An adaptive method for suppressing mechanical vibration of multiple frequencies is investigated. The adaptive controller is reinforced with saturation alleviator to improve the convergence rate and performance of the adaptive algorithm. Tracking filters are used to extract harmonics of fluctuating frequencies and the anti-saturation unit works in series with the tracking filters to give constrained harmonic output. As a result, the controller is insensitive to abnormally large input that would otherwise induce saturation in actuators. A dynamic model is built for vibration suppression simulation and the numerical results indicate that the adaptive algorithm is effective in cases of multiple fluctuating frequencies and output saturation. Experiments were also conducted to test the performance of the adaptive method. Excitation with oscillating frequencies was applied, and the results have demonstrated that the harmonics can be suppressed effectively with the adaptive method.
Cost Optimization and Flexibility Analysis for the Liquefaction of an Associated Natural Gas Stream
Authors: Eini Saeed , Kontogeorgis Georgios M. , Rashtchian Davood 
Published: November 2019

Abstract
Liquefaction and then transportation to the market is one of the promising options for the utilization of associated natural gas resources which are produced in oil fields. However, the flow of such resources is normally unsteady. Additionally, the associated gas in one oil field may exhaust in a few years and the liquefaction plant should be moved to another oil field with different specifications. In order to tackle such challenges, liquefaction systems not only must be optimally designed and operated but also should be flexible with respect to the gas flow fluctuations. The flexibility analysis of such processes is usually ignored in the optimization studies. In this research, first, the economic performance of two small-scale liquefaction processes (a single mixed-refrigerant process, SMR, and a nitrogen expander process) was optimized and compared. The results showed that the SMR process is economically more attractive (49% lower lifecycle cost compared to the nitrogen expander process). As a post-optimization step, flexibility analysis was performed to investigate the ability of optimal designs in overcoming gas flow fluctuations. For this purpose, five-thousand feed samples with different flowrate and methane content were supposed which formed a feasibility-check region. The results showed that with respect to the design constraints, the optimal SMR process is more flexible and feasibly operates in the entire region. However, the nitrogen expander process cannot feasibly operate for the gas feed with high flowrate and low methane content.
Comparative Study of the Inline Configuration Wind Farm
Authors: Hasan Alaa S. , Elgammal Tarek , Jackson Randall S. , Amano Ryoichi S. 
Published: November 2019

Abstract
This research provides an in-depth analysis of the flow around the rotor and in the wake of a single horizontal axis wind turbine (HAWT) model at different free stream velocities and tip speed ratios (TSRs). Moreover, it extracts some recommendations that might be beneficial for large-scale projects such as wind farm layout design and power output prediction. For this purpose, modeling and experimental testing of a wind tunnel test section, including a single wind turbine model inside were created and validated against present experimental data of the same model. The large Eddy simulation (LES) was used as a numerical approach to model the Navier–Stokes equations. The computational domain was divided into two areas: rotational and stationary. The unsteady rigid body motion (RBM) model was adopted to represent the rotor rotation accurately.
The conversion tectonics from spreading to subduction: Paleostress analysis of dike swarms during the subduction initiation in the Oman Ophiolite
Authors: Umino Susumu , Kusano Yuki , Yamaji Atsushi , Fudai Takahiro , Tamura Akihiro , Arai Shoji 
Published: November 2019

Abstract
We present paleostress analyses of dike swarms intruded during the subduction initiation in the northern Oman Ophiolite to understand the tectonomagmatic environment. Five swarms of subparallel dikes extending WNW-ESE are 1–5 km in width and are spaced every 5 km N-S. Each swarm has a core of 100% sheeted dikes 1–2 km in width, which emanated from the dunite-wherlite-clinopyroxenite-gabbronorite-diorite-tonalite complexes below and intruded through V1 and into V2 extrusive rocks. Individual dike strikes are varied but generally subparallel to the overall trend of the swarm. Paleostress analyses indicate subvertical σ1, ∼σ2, and subhorizontal σ3 with high magma pressures, resulted in the mutually intrusive, extensional shear dikes and abrupt changes in dike strike at high angles. These occurrences suggest intrusions under a more compressive environment compared to the extensional stress field that formed the N-S–striking sheeted dikes of V1 spreading stage. Most E-W–striking dikes possess both boninitic and tholeiitic geochemistry. The latter resemble the V1 flows and dikes with affinities of mid-ocean ridge basalt. Some tholeiitic dikes strike N-S, which are mutually intrusive to E-W–striking dikes. Tholeiitic dikes are more intensely altered than boninite, suggesting their older ages. Conversion of the stress field from a N-S–running spreading axis to inextensional E-W–running rift zones associated with the change in magma geochemistry agree with the relatively compressive V2 arc above a forced subduction zone, which originated from intraoceanic thrusting caused by the clockwise rotation of a microplate including the future northern ophiolite.
Optimising systemic insecticide use to improve malaria control
Authors: Meredith Hannah R , Furuya-Kanamori Luis , Yakob Laith 
Published: November 2019

BackgroundLong-lasting insecticidal nets and indoor residual sprays have significantly reduced the burden of malaria. However, several hurdles remain before elimination can be achieved: mosquito vectors have developed resistance to public health insecticides, including pyrethroids, and have altered their biting behaviour to avoid these indoor control tools. Systemic insecticides, drugs applied directly to blood hosts to kill mosquitoes that take a blood meal, offer a promising vector control option. To date, most studies focus on repurposing ivermectin, a drug used extensively to treat river blindness. There is concern that overdependence on a single drug will inevitably repeat past experiences with the rapid spread of pyrethroid resistance in malaria vectors. Diversifying the arsenal of systemic insecticides used for mass drug administration would improve this strategy’s sustainability.MethodsHere, a review was conducted to identify systemic insecticide candidates and consolidate their pharmacokinetic/pharmacodynamic properties. The impact of alternative integrated vector control options and different dosing regimens on malaria transmission reduction are illustrated through mathematical model simulation.ResultsThe review identified drugs from four classes commonly used in livestock and companion animals: avermectins, milbemycins, isoxazolines and spinosyns. Simulations predicted that isoxazolines and spinosyns are promising candidates for mass drug administration, as they were predicted to need less frequent application than avermectins and milbemycins to maintain mosquitocidal blood concentrations.ConclusionsThese findings will provide a guide for investigating and applying different systemic insecticides to achieve more effective and sustainable control of malaria transmission.