bluuebunny/crossref_metadata_2025_split huggingface dataset:
Etiología de nódulos pulmonares en pacientes con cáncer mamario
Authors: Alvarez Tapias Carolina , Guzmán Luis , Díaz Sandra , Carreño José , Beltrán Rafael , Buitrago Ricardo , Carvajal Carlos 
Published: April 2020

Objetivo: Describir los diagnósticos histopatológicos a partir de los casos las pacientes con cáncer de mama que fueron llevadas a resección de nódulos pulmonares en el Instituto Nacional de Cancerología (INC).
Materiales y métodos: Se desarrolló un estudio tipo serie de casos donde se describen las características clínicas, histológicas y anatomopatólogicas de un grupo de pacientes con diagnóstico confirmado de cáncer de mama de novo o que durante su enfermedad presentaron nódulos pulmonares que requirieron resección quirúrgica mediante cuña pulmonar o lobectomía en el INC, entre 1 de enero de 2015 y el 30 de abril de 2018.
Resultados: En el periodo de estudio se realizaron 225 resecciones en cuña pulmonar y lobectomías de las cuales y se seleccionaron 55 casos de los cuales el 69.1% fueron de origen neoplásico 26 (47.3%) fueron metástasis de cáncer mama, 9 (16.4%) segundo primario pulmonar y 1 (1.8%) paciente tenía concomitantemente cáncer primario pulmonar y una metástasis de mama. Otras 2 (3.6%) pacientes tenían metástasis de otros órganos, uno de recto y uno de tiroides, mientras que las 17 (30.9%) pacientes restantes presentaron reporte de lesiones pulmonares benignas en la anatomía patológica
Conclusión: La presencia de nódulos pulmonares en pacientes con cáncer de mama no siempre son secundarias a enfermedad metastásica en pulmón; pueden existir otras etiologías como cancer primario pulmonar, metástasis de otros órganos, tumores benignos o infecciones. Conocer la etiología de los nódulos pulmonares en pacientes con cáncer de mama es determinante para evaluar las opciones terapéuticas.
Physical development and idiopathic nephrotic syndrome in children
Authors: Zhdanova O. A. , Nastausheva T. L. , Batischeva G. A. , Savchenko A. P. , Stenshinskaya E. V. , Zvyagina T. G. 
Published: April 2020

INTRODUCTION.Study of physical development (PD) of children with idiopathic nephrotic syndrome (INS) includes mainly assessment of body height and weight during corticosteroid (CS) therapy; specifics of these criteria before and after the treatment are not sufficiently studied. THE AIM: to study PD of children with INS debut during CS therapy and upon its completion.PATIENTS AND METHODS.A retrospective analysis of PD was performed in 89 patients with INS in Voronezh Regional Children's Clinical Hospital No.1 during 1998-2014 using method of Z-score of body height and weight in comparison with regional standards.RESULTS.At the INS debut body height of 38.2% of the children and body weight of 41.2% accordingly were less than those of healthy children, p<0.001. Children with steroid-sensitive nephrotic syndrome (SSNS) had no difference in body height Z-score during CS therapy (0.17±1.06) and upon its completion (0.28±1.22), p=0.794. Body height was less in steroiddependent patients (SDNS) compared to SSNS patients. Z-score body weight values in children with SSNS were higher during maximum doses of CS (0.94±1.59) and returned to previous values after the therapy (-0.24±1.33), р=0,040. Patients with a frequent relapsing SSNS and SDNS had overweight and obesity remained after prednisone treatment (p=0.009).CONCLUSION.Physical development of children with INS has differences associated with CS therapy. Since body height and weight of children with INS were different from the norms before CS therapy, this could be influenced by genetic factors, which to be studied further. The results can be used to prognose CS therapy influence on PD of patients and assess prognosis of INS.
Sistem Rekomendasi Jurusan Kuliah Bagi Calon Mahasiswa Baru Menggunakan Algoritma C4.5
Authors: Ulfa Annisa , Winarso Doni , Arribe Edo 
Published: April 2020

Pada tingkatan perguruan tinggi, seseorang belajar berdasarkan suatu bidang keahlian tertentu, sehingga output dari sebuah perguruan tinggi diharapakan mampu menghasilkan sumber daya manusia yang berkualitas sesuai dengan bidang keahliannya. Salah dalam memilih jurusan kuliah biasanya disebabkan karena kurangnya pengetahuan mengenai jurusan yang ada. Sehingga pemilihan jurusan harus dilakukan sedini mungkin dengan penuh pertimbangan. Salah satu cara dengan menggunakan sistem rekomendasi pemilihan jurusan bagi calon mahasiswa baru berdasarkan nilai sekolah, nilai tes dan jurusan sekolah menggunakan algoritma C4.5. Tujuan penelitian ini adalah menghasilkan suatu sisem rekomendasi jurusan kuliah bagi calon mahasiswa baru menggunakan algoritma C4.5. Luaran penelitian ini adalah sebuah sistem rekomendasi bagi calon mahasiswa baru yang masih kebingungan dalam menentukan jurusan kuliah. Hasil evaluasi algoritma C4.5 yang dilakukan dengan menggunakan confussion matrix diapatkan tingkat akurasi sebesar 12%. Hal ini menunjukkan bahwa sistem akan gagal melakukan rekomendasi yang sesuai karena data dan variabel yang digunakan kurang mendukung namun apabila data maupun variabel yang digunakan mendukung maka sistem akan bisa melakukan rekomendasi dengan benar.

Keywords: C4.5, Decision Tree, Rekomendasi.
Analisis Kualitas Layana E-Commerce C2C-Classifieds Terhadap Kepuasan Pengguna Dengan Menggunakan Metode Webqual 4.0
Authors: Siswaka Fikri 
Published: April 2020

Perkembangan internet yang terus naik di indonesia membuat para pembisnis di indonesia juga mengalami perkembangan , adapaun bisnis yang lagi berkembang pesat saat ini yaitu electronic commerce (E-Commerce). E-Commerce merupakan suatu kontak transaksi perdagangan antara penjual dan pembeli dengan menggunakan media internet. Di indonesia sendiri sudah banyak E-Commerce yang bermunculan hingga saat ini, salah satu nya yaitu Olx.co.id. Tujuan dari penelitian ini yaitu untuk mengetahui seberapa besar pengaruh kualitas website Olx.co.id terhadap kepuasan pengguna yang berada di Pekanbaru dengan menggunakan metode webqual dengan alat bantu SPSS 24.0. Penelitian ini adalah tipe penelitian kuantitatif dengan menggunakan metode survey. Teknik pengambilan sampel pada penelitian ini menggunakan teknik non probability yakni Teknik sampling insidental. Rumus penentuan jumlah sampel yang digunakan yaitu rumus Lemeshow. Jadi dalam penelitian ini di dapatlah jumlah sampel sebanyak 130 responden.
Penerapan Metode Logika Fuzzy dalam mengolah pilihan pada Game Visual Novel Informasi Penerimaan Mahasiswa Baru Fakultas Ilmu Komputer Universitas Muhammadiyah Riau sebagai Sarana Evaluasi Mandiri
Authors: Rizki Yoze , Mukhtar Harun , Andikarama M Djodi 
Published: April 2020

Perkembangan global erat kaitannya dengan kemajuan teknologi informasi dan dengan berkembangnya informasi memungkinkan masyarakat dapat mengakses informasi secara lebih mudah contohnya melalui gadget smartphone android. Pencarian informasi penerimaan mahasiswa baru oleh Universitas Muhammadiyah Riau dapat ditemukan melalui website, brosur, kontak telfon, dan social media. Seiring dengan bertambahnya kuota yang disediakan untuk mahasiswa baru, maka informasi penerimaan sangat diperlukan untuk menunjang proses penyebaran informasi akan tetapi sampai saat ini Universitas Muhammadiyah Riau sendiri belum memiliki sarana informasi berbasis aplikasi android untuk menunjang sosialisasi informasi kepada calon mahasiswa baru. Melihat permasalahan yang ada penelitian ini bertujuan untuk membangun sarana alternatif untuk membantu sosialisasi informasi kepada calon mahasiswa baru. Maka dari itu penulis akan membangun sebuah media untuk membantu calon mahasiswa baru agar bisa mendaptkan informasi Penerimaan Mahasiswa Baru (PMB) melalui media game khsususnya untuk Fasilkom UMRI. Game yang akan digunakan yaitu bertipe Visual Novel. Visual Novel sendiri terdiri dari gambar, suara, dan cerita yang nantinya dapat membantu dalam proses penyediaan informasi. Tujuan lain dari penelitian ini adalah untuk merancang alur cerita game dengan Finite State Machine serta mengimplementasi metode Logika Fuzzy untuk mengolah pilihan pada Mini Game Evaluasi dan nantinya game ini akan dibangun menggunakan Ren’Py dengan bahasa pemrograman Phyton. Dengan dibuatnya penelitian ini diharapkan dapat membantu calon mahasiswa baru Fasilkom untuk mendapatkan informasi PMB secara menarik, simpel, dan interaktif. Hasil pengujian fungsional game yang telah dihitung persentasenya pada responden menunjukkan bahwa 100% menyatakan ya setuju dan menyatakan 0% tidak setuju, dapat disimpulkan dari hasil semua responden bahwa game yang dibuat berfungsi sebagaimana mestinya. Hasil pengujian usabilitas game hasil pengujian antarmuka diperoleh kesimpulan bahwa hampir seluruh koresponden puas dengan game yang dibuat. Data hasil pengujian menunjukkan bahwa responden sangat setuju 83%, setuju 15%, netral 2%, tidak setuju 0%, dan menyatakan sangat tidak setuju 0%.
Methodical approach to evaluation of economic efficiency of repairing the weapons and military equipment
Authors: Dachkovskyi Vоlodymyr , Sampir Oleksandr , Horbachova Yana 
Published: April 2020

The analysis of using the military units and formation during conduct of hostilities on the territory of Donetsk and Luhansk region allows to claim that the one of the main aspect that impact on the success in the execution of tasks are existence of workable samples of weapons and military equipment. Thus, the one of the main source of entering of workable samples of weapons and military equipment in military units (military formations) during conduct of hostilities is returning them from stationary and movable damage-control military formations (units) after the completion of their restoration. Accordingly, during the restoration of damaged samples of weapons and military equipment consumes replacement parts, assemblages, aggregates, components equipment etc. that need to be purchased from manufacturers, which has resulted to financial and economic costs.
Therefore, in this work are proposed the methodical approach to evaluation of economic efficiency of repairing samples of weapons and military equipment. This approach includes two ways: financial and economic costs on the repairing of weapons and military equipment in the stationary conditionals and in the moving repair and reconstruction military formations (units). The main costs will be focused on the principal salary of repairmen, the basic materials, replacement parts, overhead of mechanical department, common overhead, new product development costs, and special costs during the repairing of weapons and military equipment in stationary conditions. And the basic spending will be focused on the purchasing of new details, assemblages, aggregates, depreciation cost of equipment, the cost of maintaining the personnel of repair specialists, average cost of operational set during the repairing of weapons and military equipment in the moving repair and reconstruction military formations (units).
Development of methodology of alternative rationale for financial ensuring of bridges building
Authors: Britchenko Igor , Bezpartochnyi Maksym , Levchenko Yaroslava 
Published: April 2020

The purpose of the article is to develop a methodology for alternative substantiation of financial support for bridge construction. To achieve the purpose, the following general scientific and special methods and techniques of research were used: “golden ratio” rule; systematization and generalization; generalization of the results of the analysis and the logical generation of conclusions. Initially, the article analyzed the state of bridge structures in Europe and Ukraine. Based on the analysis, a disappointing situation has been identified, namely that a significant ratio of bridges number require major overhaul or are in critical condition. During the research, the following tasks were solved, namely: physical wear of the bridge as a failure was considered; the feasibility of investing in reconstruction or new bridge construction was determined.
For the purpose of rational use of financial resources, which are limited in the age of economic challenges, and on the basis of the rule of “golden proportion”, the maximum percentage of investment in reconstruction is determined. If the limit is exceeded, it is decided to build a new bridge. This result allows making an economically sound decision and evaluating the effectiveness of the invested resources. It is proved that if the wear index of the overhaul bridge construction is higher than the wear rate of the new bridge construction by λ2 / λ1, and the amount of funds for overhaul reaches 70% of the funds needed to build a new one, it is better to build a new bridge.
The Extended Kardashev Scale
Authors: Gray Robert H. 
Published: April 2020

Abstract
A scale is described for classifying civilizations according to the amount of power they produce, using the whole numbers 0 through 4 to denote 106, 1016, 1026, 1036, and 1046 W corresponding to the approximate power available at physical scales biological, planetary, stellar, Galactic, and observable universe, extending a Roman numeral scheme introduced by Kardashev and updating it with suggestions from Sagan and Lemarchand including using Arabic numbers to permit decimal subdivisions. Terrestrial civilization circa 2015 would be classified as Type 0.72 on this extended and updated scale. Similar scales can be used to classify information stored, population, and mass of constructions.
The Importance of Star Formation Intensity in Lyα Escape from Green Pea Galaxies and Lyman Break Galaxy Analogs
Authors: Kim Keunho , Malhotra Sangeeta , Rhoads James E. , Butler Nathaniel R. , Yang Huan 
Published: April 2020

Abstract
We have studied ultraviolet images of 40 Green Pea galaxies and 15 local Lyman Break Galaxy Analogs to understand the relation between Lyα photon escape and central UV photometric properties. We measured star-formation intensity (SFI; star formation rate per unit area) from the central 250 pc region (

) using Cosmic Origins Spectrograph near-ultraviolet images from the Hubble Space Telescope. The measured

of our sample Green Peas ranges from 2.3–46 M
☉ yr−1 kpc−2, with a geometric mean of 15 M
☉ yr−1 kpc−2 and a standard deviation of 0.266 dex, forming a relatively narrow distribution. The Lyman Break Galaxy Analogs show a similarly narrow distribution of

(0.271 dex), though with a larger mean of 28 M
☉ yr−1 kpc−2. We show that while the Lyα equivalent width (EW(Lyα)) and the Lyα escape fraction (

) are not significantly correlated with the central SFI (

), both are positively correlated with the ratio of surface brightness to galaxy stellar mass (S
250 pc/M
star), with correlation coefficients (p-values) of 0.702 (1 × 10−8) and 0.529 (5 × 10−4) with EW(Lyα) and

, respectively. These correlations suggest a scenario where intense central star formation can drive a galactic wind in galaxies with relatively shallow gravitational potential wells, thus clearing channels for the escape of Lyα photons.
Scattering-induced Intensity Reduction: Large Mass Content with Small Grains in the Inner Region of the TW Hya disk
Authors: Ueda Takahiro , Kataoka Akimasa , Tsukagoshi Takashi 
Published: April 2020

Abstract
Dust continuum observation is one of the best methods to constrain the properties of protoplanetary disks. Recent theoretical studies have suggested that dust scattering at the millimeter wavelength potentially reduces the observed intensity, which results in an underestimate in the dust mass. We investigate whether dust scattering indeed reduces the observed continuum intensity by comparing the ALMA archival data of the TW Hya disk at Bands 3, 4, 6, 7, and 9 to models obtained by radiative transfer simulations. We find that the model with scattering by 300 μm-sized grains well reproduces the observed spectral energy distribution of the central part of the TW Hya disk while the model without scattering is also consistent within the errors of the absolute fluxes. To explain the intensity at Band 3, the dust surface density needs to be ∼10 g cm−2 at 10 au in the model with scattering, which is 26 times more massive than previously predicted. The model without scattering needs a 2.3 times higher dust mass than the model with scattering because it needs a lower temperature. At Band 7, scattering reduces the intensity by ∼35%, which makes the disk look optically thin even though it is optically thick. Our study suggests the TW Hya disk is still capable of forming cores of giant planets at locations analogous to where the current solar system planets exist.
La beauté est-elle universelle ?
Authors: Marchal Marion 
Published: April 2020

Nous avons renoncé à la croyance en un critère objectif du beau ; nous savons que nous sommes maintenant installés dans le relativisme esthétique. Comment en sommes-nous arrivés à ne plus pouvoir justifier nos appréciations par un critère unique ? Faut-il regretter cette nouvelle situation ? Ne faut-il pas plutôt reconnaître qu’en elle se libèrent non seulement la diversité des goûts mais surtout celle des productions artistiques ?
Même en opération ! République centrafricaine, 2013
Authors: Briganti Arnaud 
Published: April 2020

« Il faut connaître la pourriture, car seul qui connaît la nuit peut apprécier la lumière », écrivait Ernst Jünger. L’opération Sangaris, menée en Centrafrique par l’armée française, témoigne de ce contraste entre la noirceur de la violence et les signes encore perceptibles d’une beauté fragile.
Quand Proust révèle la beauté de la stratégie militaire
Authors: Fraisse Luc 
Published: April 2020

Marcel Proust (1871-1922), s’il n’a pas combattu durant la Grande Guerre, a réuni par une abondante lecture de la presse une documentation très précise sur les opérations, se passionnant pour la stratégie. Dans Le Côté de Guermantes I (1920), le héros d’ À la recherche du temps perdu séjourne dans la ville fictive de garnison Doncières, où Saint-Loup et ses amis développent une théorie sur la beauté des opérations stratégiques, qui exercera une grande influence sur l’avenir littéraire du personnage, destiné à devenir écrivain.
Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Authors: Schreiner Philipp , Harrer Thomas , Scheibenbogen Carmen , Lamer Stephanie , Schlosser Andreas , Naviaux Robert K , Prusty Bhupesh K 
Published: April 2020

Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disorder with many possible triggers. Human herpesvirus (HHV)–6 and HHV-7 are two infectious triggers for which evidence has been growing. To understand possible causative role of HHV-6 in ME/CFS, metabolic and antiviral phenotypes of U2-OS cells were studied with and without chromosomally integrated HHV-6 and with or without virus reactivation using the histone deacetylase inhibitor trichostatin-A. Proteomic analysis was conducted by pulsed stable isotope labeling by amino acids in cell culture analysis. Antiviral properties that were induced by HHV-6 transactivation were studied in virus-naive A549 cells challenged by infection with influenza-A (H1N1) or HSV-1. Mitochondria were fragmented and 1-carbon metabolism, dUTPase, and thymidylate synthase were strongly induced by HHV-6 reactivation, whereas superoxide dismutase 2 and proteins required for mitochondrial oxidation of fatty acid, amino acid, and glucose metabolism, including pyruvate dehydrogenase, were strongly inhibited. Adoptive transfer of U2-OS cell supernatants after reactivation of HHV-6A led to an antiviral state in A549 cells that prevented superinfection with influenza-A and HSV-1. Adoptive transfer of serum from 10 patients with ME/CFS produced a similar fragmentation of mitochondria and the associated antiviral state in the A549 cell assay. In conclusion, HHV-6 reactivation in ME/CFS patients activates a multisystem, proinflammatory, cell danger response that protects against certain RNA and DNA virus infections but comes at the cost of mitochondrial fragmentation and severely compromised energy metabolism.
Primary Rectal Lymphoma with Synchronous Liver Involvement: An Extremely Rare Case Report
Authors: Rastogi Kartick , Jain Sandeep , Sharma Shantanu , Jindal Arpita 
Published: April 2020

AbstractBoth primary rectal lymphoma (PRL) and primary hepatic lymphoma are rare entities, concomitant NHL in rectum and liver is an extremely rare coincidence. Cases of primary colonic lymphoma however can be found in literature. We report an extremely rare case of PRL with synchronous liver involvement after obtaining written informed consent, with a review of available literature. The case was provisionally diagnosed to be an adenocarcinoma of rectum with liver metastasis, with final confirmation on immunohistochemistry. PRL with synchronous liver involvement is an extremely rare coincidence. It is usually confused with more common adenocarcinoma of rectum with liver metastasis posing diagnostic challenges. The optimal management of PRL has never been validated through randomized trials. The treatment options include chemotherapy, radiation, surgical treatment, or a combination of these. Chemotherapeutic agents of choice are the cyclophosphamide, doxorubicin, vincristine, and prednisone regimen, with or without monoclonal antibody rituximab.
Daratumumab
Authors: Gopal Vishnu , Dubashi Biswajit 
Published: April 2020

AbstractMultiple myeloma is a proliferative disorder of plasma cells in the bone marrow with excessive monoclonal protein production. Despite the evolution of multiple drugs and management strategies including maintenance and autologous stem cell transplantation, the long-term results still remain undesirable. Those patients with double refractoriness to immunomodulatory drugs and proteosome inhibitors have dismal prognosis and rarely get back into durable remission. The identification of CD38 as a therapeutic target for multiple myeloma resulted in the clinical development of anti-CD38 antibodies. Daratumumab is an IgG1 human monoclonal antibody that binds to the CD38 protein. The implementation of daratumumab in clinical practice is widely considered as a significant milestone in the management of multiple myeloma. The salient pharmacological aspects and clinical evolution of the drug are briefly discussed in this review.
Recurrent Giant Intrahepatic Biliary Cystadenoma: Case Report and Review of Literature
Authors: Sharma Digvijoy , Gondu Gangadhar Rao , Thamma Venu Madhav , Gunturi Surya Ramachandra Varma , Kishore Kunduru Nava , Reddy Jagan Mohan , Bheerappa Nagari 
Published: April 2020

AbstractBiliary cystadenoma is a very rare cystic neoplasm of the liver that usually occurs almost exclusively in middle-aged women. These are slowly progressive tumours and cannot be safely differentiated from cystadenocarcinomas on preoperative imaging and hence should always be considered for resection. Historically these cystic tumors have been treated by a variety of techniques including aspiration, fenestration, internal drainage, partial resection resulting in high rates of recurrence. In addition biliary cystadenoma is a premalignant lesion and only surgical excision can differentiate it from its malignant counterpart, biliary cystadenocarcinoma.