bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and characterization of magnetic nanoparticle-incorporated nanohydroxyapatite and calcium and phosphate ion clusters for biomimetic remineralization of enamel and dentin
Authors: Basam Ram Chowdary , Bolla Nagesh , Vemuri Sayesh , Garlapati Roopadevi , Dasari Ankineedu Babu , Lahari B 
Published: December 2024

Aim:
The present study aimed to synthesize and characterize magnetic nanoparticle incorporated nanohydroxyapatite (MNHAP), calcium and phosphate ion clusters (CPICs), and their combination with MNHAP.

Materials and Methods:
Nanohydroxyapatite (NHAP), magnetite (Fe3O4), and magnetic nanoparticle-incorporated nanohydroxyapatite (MNHAP) were synthesized using wet precipitation method, co-precipitation method, and ultrasonic-assisted mechanical stirring methods, respectively. CPIC was synthesized by centrifugation method. Their characterizations were analyzed through X-ray diffraction (XRD) crystallography, Fourier-transform infrared spectroscopy (FTIR), vibrating sample magnetometer (VSM), and high-resolution transmission electron microscopy. The biocompatibility of MNHAP was assessed through the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.

Results:
XRD substantiated the presence of diffraction peaks, indicating crystallinity in all synthesized samples. Functional groups in NHAP and MNHAP were confirmed through FTIR analysis. VSM analysis demonstrated superparamagnetic behavior in both MNHAP and Fe3O4. Transmission electron microscope images unveiled the needle-like crystals for NHAP, rod-shaped crystals for MNHAP, and polyhedral shapes for CPIC combined with MNHAP (CPIC + MNHAP). MNHAP exhibited biocompatibility up to 200 µg.

Conclusion:
Based on the findings of this study, MNHAP and CPIC + MNHAP may be suitable for the repair of initial caries lesions.
Analysis of Blood Utilization Practices and Quality Indicators in a South Indian Teaching Hospital in Puducherry, India
Authors: Paudel Purshotam , Sinha Pammy , Manoharan A. , Jayakumar Pooja Shri 
Published: December 2024

Abstract

Introduction:
The transfusion of donated blood is the mainstay of treatment for medical or surgical conditions. It is the primary responsibility of blood transfusion services to provide a safe, sufficient, and timely supply of blood products. It is recommended to conduct regular audits to know usage trends. This study aims to analyze the utilization pattern and quality indicators of transfusion services.

Materials and Methods:
This is a retrospective study conducted in the blood center of a tertiary care teaching hospital in Puducherry, India. We collected and analyzed data on the request and utilization of blood and its products from January 2023 to December 2023. The department-wise utilization of blood and its components, crossmatch to transfusion ratio (C: T ratio), transfusion probability (T%), and transfusion index (TI), were calculated.

Results:
Packed red blood cells (PRBCs) were the most utilized blood product. The intensive care unit ward received the highest blood supply, followed by obstetrics/gynecology and orthopedics. Patients with anemia, followed by surgery and pregnancy, required a majority of PRBCs. The CT ratio, TI, and TP% were 2.7%, 0.42%, and 0.37%, respectively.

Conclusions:
The overall transfusion indicators, namely C/T ratio, TI, and TP, were near optimal compared to standard values. However, the majority of the cross-matched blood remained unused. It is crucial to conduct a periodic review of the blood component usage in a hospital.
Dental Robotics – A Game Changer
Authors: Dewan Harisha , Dhar Antarik , Patel Ria H. , Nayak Sarat Kumar , Debata Tribikram , Subramani Savadamoorthi Kamatchi 
Published: December 2024

ABSTRACT

Introduction:
This systematic review was done to present the role of robots in dentistry.

Materials and Methods:
The search was conducted using the terms “dental robotics,” “robotic-assisted dentistry,” “robotic surgery in dentistry,” “robotics in dental procedures,” and “automated dental systems.”

Results:
Out of the 607 publications analyzed, only six were chosen and included in the calculations based on their publication year.

Conclusion:
Precision and accuracy in robotics are discussed and used in many fields, yet they have limitations. In impoverished nations, robots replacing people is science fiction, always seeking improvement. Therefore, robotic dentistry is a fiction that could become real soon.
Comparative Effectiveness of Modified Manual and Powered Toothbrushing Interventions in Individuals with Disabilities: A Randomized Controlled Trial Assessing Gingival Health
Authors: Sinha Abhishek , Kumar Sumit , Sargaiyan Vinod , Kottapalli Ruby H. , Sharma Dheeraj , Goyal Ankit 
Published: December 2024

ABSTRACT

Background:
Individuals with disabilities face unique challenges in maintaining optimal oral health due to physical, cognitive, and sensory impairments. Gingivitis is a common oral health problem in this population, necessitating effective interventions tailored to their specific needs.

Methods:
Participants (n = 162) aged 18–65 years, diagnosed with gingivitis and varying disabilities, were recruited. They were randomly assigned to the modified manual toothbrush group or the powered toothbrush group. The interventions included comprehensive training programs that addressed the specific needs of each group. Gingival index and plaque index scores were recorded at baseline and at 4, 8, and 12 weeks. Patient-reported outcomes, including satisfaction, comfort, and ease of use, were assessed. Statistical analyses were performed, including t-tests, Chi-square tests, and subgroup analyses based on disability types.

Results:
Baseline characteristics did not demonstrate significant differences between groups. Over 12 weeks, both groups showed a significant reduction in gingival and plaque index scores (P < 0.001). The powered toothbrush group exhibited a slightly greater reduction in gingival inflammation compared to the manual toothbrush group (P = 0.03). Patient-reported results favored the powered toothbrush group in satisfaction (P = 0.02) and ease of use (P = 0.04). Comfort levels did not show significant differences (P = 0.11).

Conclusions:
This randomized controlled trial provides evidence supporting the effectiveness of modified manual and powered toothbrushing interventions in reducing gingival inflammation among people with disabilities diagnosed with gingivitis.
Comparative Study of Conventional Impressions vs Intraoral Scanning for Complete Denture Fabrication
Authors: Nagar Priya , Prasad D Anupama , Satapathy Sukanta K. , Vigneswaran T. , Francis Mariea , Vijaysingh Jadhav Avantika 
Published: December 2024

ABSTRACT

Background:
Conventional impression techniques for complete denture fabrication, although traditional, often pose challenges regarding accuracy and patient comfort. Intraoral scanning offers a digital alternative that promises enhanced precision and patient satisfaction. This study aimed to compare the efficacy, accuracy, and patient outcomes between conventional impression methods and intraoral scanning for the fabrication of complete dentures.

Materials and Methods:
A total of 100 edentulous patients were randomly assigned to two groups: one group receiving conventional impressions (n = 50) and the other undergoing intraoral scanning (n = 50). The primary outcome measures included impression accuracy (assessed by comparing final denture fit), time efficiency (total clinical time from impression to denture delivery), and patient satisfaction (evaluated through a standardized questionnaire). Statistical analysis was performed using the Chi-squared test for categorical data and t-tests for continuous variables.

Results:
The intraoral scanning group demonstrated significantly higher accuracy in denture fit, with 92% of patients reporting excellent fit compared to 74% in the conventional group (P < 0.05). Time efficiency was also enhanced in the intraoral group, with a reduction in total clinical time of 25%. Patient satisfaction scores were notably higher in the intraoral scanning group (8.6 ± 0.5 on a 10-point scale) compared to the conventional group (6.9 ± 1.0). No significant complications were reported in either group.

Conclusion:
Intraoral scanning proves to be a superior technique for the fabrication of complete dentures compared to conventional methods, offering better denture fit, reduced clinical time, and improved patient satisfaction. These findings suggest that intraoral scanning could replace traditional impression methods in clinical practice for edentulous patients.
Efficacy of Articaine versus Lignocaine as Local Anesthetic Agents Using Buccal Infiltration Technique for Extraction of Mandibular Premolars
Authors: Kolte Deepak , Kalsi Harjit Singh , Kharkar Viraj Rajeev , Patil Tejal , Kumar Barun , Wagh Ashvin , Sachdev Sanpreet Singh 
Published: December 2024

ABSTRACT

Introduction:
Lignocaine, commonly used for local anesthesia, often results in discomfort during mandibular premolar extractions due to limited tissue diffusion with the buccal infiltration technique. Articaine, with better lipid solubility, promises improved diffusion and patient comfort. This study compares the efficacy of 2% Lignocaine and 4% Articaine in reducing pain during mandibular premolar extractions.

Methodology:
A split-mouth, randomized, controlled trial included 40 patients, aged between 18 and 40 years, undergoing bilateral mandibular premolar extractions. Each patient received 4% Articaine with adrenaline and 2% Lignocaine with adrenaline on opposite sides at separate appointments. Pain was assessed using the Visual Analog Scale (VAS) and Faces Pain Scale (FPS).

Results:
Patients in the Articaine group reported significantly lower pain levels (mean FPS: 0.2) compared to the Lignocaine group (mean FPS: 3.6) (P < 0.001). In the Articaine group, 34 out of 40 patients experienced no pain, whereas all patients in the Lignocaine group reported mild to severe pain. Mild pain was reported by 23 patients in the Lignocaine group, and moderate pain by 12 (P < 0.05). No severe pain was recorded in the Articaine group.

Conclusion:
Articaine demonstrated superior pain control, making it a more effective choice over Lignocaine for mandibular premolar extractions using the buccal infiltration technique.
Evaluation of the Effect of Supragingival Scaling on Periodontal Parameters in Pregnant Women with Metabolic Syndrome
Authors: Sayeed Ghousia , Varghese Sheeja S. 
Published: December 2024

ABSTRACT

Background:
Although there are quite a number of studies on the impacts of periodontal therapeutic management on pregnant females, literature on the impact of supragingival scaling on pregnant females with metabolic syndrome (MS) is wanting. The present investigation was meticulously formulated to ascertain the clinical ramifications of supragingival scaling in pregnant individuals diagnosed with MS.

Material and Methods:
An intervention study was conducted on 47 pregnant females. The gingival index (GI), plaque index, bleeding on probing, probing depth, and clinical attachment level were among the periodontal parameters evaluated. By the end of 20–21 weeks of pregnancy, all participants had received scaling and polishing at the baseline appointment, along with advice on dental hygiene. Periodontal parameters were gathered again during a follow-up appointment 8 weeks post treatment. A 5% threshold for statistical significance was set, and paired t-test and chi-square test were applied for comparison.

Results:
Lower levels of PI, GI, and BOP 8 weeks post supragingival scaling were noted than at the baseline. The results obtained were statistically significant (P < 0.001) All patients with severe periodontitis (n = 14) before supragingival scaling shifted to milder forms of the disease. Similarly, moderate periodontitis was seen in 20 patients before the start of the study, and after the intervention, it was reduced to 16 patients.

Conclusion:
In summary, supragingival scaling lowers the incidence of periodontal disease in pregnant MS females. High-risk pregnant women who receive scaling treatment and instruction on oral hygiene on a regular basis have better oral health, which in turn improves the health of their unborn child.
Probiotics in the Prevention and Treatment of Periodontal Diseases: A Systematic Review
Authors: Abdul Nishath Sayed , Odeh Lara Ghassan , Alenazi Asma Awadh , Alzahrani Jumana Abdullah , Almutib Aldanah Tawfiq , Soman Cristalle 
Published: December 2024

ABSTRACT

Introduction:
Periodontal diseases (PDs) pose a significant challenge to dental health, leading to a growing interest in probiotics as potential therapeutic and prophylactic agents. Literature evidence has shown conflicting results on the use of probiotics in the management of PDs. Hence, this systematic review was performed to explore the effectiveness of probiotics in both the prevention and treatment of PDs by synthesizing data from relevant studies.

Methodology:
Various databases were searched using appropriate MeSH keywords as per the PRISMA protocol. Studies were included only if they met certain criteria. Two reviewers independently extracted data variables from the included literature. The risk of bias 2.0 tool was employed to assess the methodological quality of the included studies.

Results:
In total, 21 studies were considered eligible and included in the review. It was observed that 17 studies reported a statistically significant improvement in both periodontitis and gingivitis among the probiotic group compared to control cohorts. The synthesized evidence from the review suggests that probiotics play a favourable role in both the prevention and treatment of PDs.

Conclusion:
It also supports the incorporation of probiotics as a potential adjunctive therapy in PD management. However, further research is warranted to explore the specific probiotic strains, dosages, and treatment durations for optimized outcomes.
Exploring Societal Fears of Aging and Loss of Beauty in Disney Film “Tangled” and Indian Film “Yashoda”: A Feminist Film Analysis
Authors: Gopalakrishnan Bhuvaneswari , Borah Rashmi Rekha , Lakshmi M. Subbu 
Published: December 2024

The fear of aging and the loss of beauty is a pervasive societal issue that transcends cultural boundaries, often manifesting in the media and film industry. This paper examines the 2010 animated film “Tangled” and an Indian Film “Yashoda” (2022) through a feminist lens, focusing on the themes of fears of aging and loss of beauty. It analyses how the antagonists, Gothel (Tangled) and Madhubala (Yashoda) navigate their journey in maintaining their beauty and youth which is a stereotypical expectation of the society. This study examines the portrayal of societal fears regarding aging and the loss of beauty through a feminist lens in the Disney film “Tangled” and the Indian film “Yashoda.” Both films, while culturally distinct, navigate the complex terrain of beauty standards, aging, and female autonomy. “Tangled” presents the narrative of Rapunzel, whose magical hair symbolizes youth and beauty, coveted by the antagonist, Mother Gothel, to prevent her own aging. This dynamic serves as a metaphor for the societal obsession with youth and the lengths to which individuals will go to preserve beauty.
The paper employs a feminist film analysis methodology to uncover how these narratives contribute to and critique the cultural discourse on aging and beauty. It investigates how the films’ portrayal of female villains against the backdrop of societal beauty standards speaks to larger themes of female agency, body autonomy, and the commodification of women’s bodies. By comparing the Western and Indian cinematic contexts, the study reveals the universal and culturally specific aspects of how women’s aging and beauty are depicted and the implications of these portrayals for feminist discourse. This analysis contributes to a broader understanding of how cinema reflects, reinforces, and challenges the societal fears of aging and loss of beauty.
Study of complications associated with central vein catheterization in patients with blood disorder
Authors: Romanenko N. A. 
Published: December 2024

Introduction. Central venous catheter (CVC) provides intensive infusion and transfusion therapy in cancer patients, but catheter placement and operation are often associated with complications.Objective. To determine the incidence of complications associated with CVC in patients with blood disorders.Materials and methods. The study involved 3115 patients and 46 bone marrow donors. The right subclavian vein was catheterized in 2600 (82.2%) patients, the left subclavian vein in 552 patients (17.5%), and the internal jugular vein in 9 patients (0.3%). All persons underwent radiologic control; bacteriological blood examination was performed in case of suspected infection.Results. Early revealed complications were: hematoma in 4.0% of patients; bleeding — in 2.3%; subclavian artery puncture — in 2.7%; pain and paresthesia of the upper limb — in 1.7%; lymphorrhea — in 1.4%; weakness / collapse — in 1.2%; extravasation — in 1.1%; catheter thrombosis — in 1.1%; less frequently, pneumothorax was detected in 0.2% of patients; allergic reaction to anesthetic — in 0.1%. Delayed complications (infiltrate, phlebitis, thrombophlebitis) were diagnosed in 2.7% of patients, bacteremia — in 2.4%, delayed bleeding — 0.4%. Among infections, Gram positive microorganisms were more frequently detected in 61.8% of cases, Gram negative in 29.7% (p < 0.01), and rarely fungal pathogens in 8.5% (p < 0.001). It was not possible to catheterize the central vein due to anatomical features of the patient in 0.5% of cases.Conclusions. The analysis of trunk vein catheterization in patients with blood disorders established a high rate of hematomas, bleeding, subclavian artery punctures; among delayed complications, infiltrate, phlebitis, and bacteremia. Infectious complications demonstrated a prevalence of Gram-positive infectious agents.
Pathobiochemical aspects of divers barodentalgia
Authors: Klenkov I. R. , Krivonos A. S. , Grashin R. A. , Pototskaya A. V. , Zheleznyak V. A. , Maday I. S. 
Published: December 2024

Introduction. During their descent under water, divers may suffer from acute toothache attacks (barodentalgia), creating an emergency that leads to the termination of diving descent. Barodentalgia can be caused by hypoxic process in the pulp of filled teeth under increased intrapulpal pressure.Objective. To reveal the peculiarities of hypoxic processes in the pulp of filled teeth under hyperbaric exposure basing on oximetry and fluorescence change parameters.Мaterials and methods. The study involved 34 male divers who underwent a dental examination at the first stage to select individuals for the second stage of the experiment. 24 subjects were selected for the second stage and evaluated for oximetric (mixed blood saturation) and fluorescent (reduced coenzyme NADH, oxidized coenzyme FAD, fluorescent oxygen consumption index — FOCI) indices of filled teeth. The evaluation was performed by optical tissue oximetry (OTO) and laser-induced fluorescence (LIF) methods before and after immersion in a barocamera at pressure of 0.4 MPa while breathing air.Results. Following exposure to increased pressure of the gas medium as compared to the initial values in the filled teeth, the following phenomena were observed: decrease in pulp saturation by 33.7% (p<0.05); increase in NADH by 14.4%; decrease in FAD by 22.9%; increase in FOD by 73.4% (p<0.05).Conclusions. The revealed changes in the indicators of mixed blood saturation, NADH, FAD and FOCI confirm the presence of hypoxic process in the pulp of filled teeth under hyperbaric exposure.
A modern approach to the differential diagnosis of human betaherpesvirus infection 6A/V in children
Authors: Tian N. S. , Babachenko I. V. , Goleva O. V. , Zhelezova L. I. , Baziyan E. V. , Glotov O. S. 
Published: December 2024

Introduction. Herpesvirus infections — in particular, those caused by human betaherpesvirus 6A/B (HHV-6A/C), are a serious problem at the present time due to their ubiquity, polymorphism of manifestations, lifelong persistence in the body with the possibility of reactivation, and need for comprehensive diagnostics to the form of infection. Herpesvirus infections are especially serious when occurring in children with recurrent respiratory diseases.Objective. To propose a modern method of differential diagnosis (DD) of active and latent forms of HHV-6A/B infection in children to optimize patient management tactics.Materials and methods. To build a discriminant model, 152 patients aged 1 month to 17 years inclusive were included in the study, 112 of them making up a training sample, while 40 comprised a test sample. A dichotomous variable was taken as a response variable: 1 — latent form of HHV-6A/B infection (n = 89), 2 — active (n = 23). 27 potential predictors were considered. The test sample consisted of 40 children. Statistical processing was performed using Microsoft Excel and StatSoft Statistica 7.0 Results. The developed prognostic model of DD of active and latent forms of HHV-6A/B infection in children, which takes into account the severity of fever, the presence of cough, the absolute neutrophil count and the value of threshold cycles of HHV-6A/B DNA, is characterized by its high sensitivity (91.3%) and specificity (94.4%). The presented example reflects the step-by-step use of the model.Conclusions. The prognostic model can be used in practice for identifying DD forms of HHV-6A/B infection in the presence of lymphoproliferative and respiratory syndromes in children, for the detection of HHV-6A/B DNA in the blood, and to substantiate indications for immunotropic therapy.
Nghiên cứu chế tạo và ứng dụng màng chọn lọc trong thu hồi hơi xăng dầu
Authors: Duong Chi Trung  , Nguyen Thi Binh  , Phan Minh Quoc Binh  , Do Ngoc Vinh  
Published: December 2024

Bài viết trình bày kết quả nghiên cứu phát triển màng chọn lọc để tách hydrocarbon từ hỗn hợp với không khí, sử dụng phương pháp phủ lớp chọn lọc lên lớp chất nền và đóng gói dạng xoắn ốc (spiral wound) để ứng dụng trong hệ thống thu hồi hơi xăng tại các cửa hàng xăng dầu. Màng được chế tạo từ tấm nền PTFE 0,45 µm với lớp phủ RTV 828 có khả năng chọn lọc và độ thấm cao, quy trình đơn giản, chi phí thấp và khả năng sản xuất quy mô lớn. Kết quả thử nghiệm trong hệ thống thu hồi hơi xăng cho thấy hiệu suất thu hồi trên 90%, mở ra triển vọng ứng dụng trong công nghiệp và bảo vệ môi trường.