bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic Value of Ambulatory Blood Pressure Load in Pediatric CKD
Authors: Lee Jason , McCulloch Charles E. , Flynn Joseph T. , Samuels Joshua , Warady Bradley A. , Furth Susan L. , Seth Divya , Grimes Barbara A. , Mitsnefes Mark M. , Ku Elaine 
Published: March 2020

Background and objectives
Elevated BP load is part of the criteria for ambulatory hypertension in pediatric but not adult guidelines. Our objectives were to determine the prevalence of isolated BP load elevation and associated risk with adverse outcomes in children with CKD, and to ascertain whether BP load offers risk discrimination independently or in conjunction with mean ambulatory BPs.

Design, setting, participants, & measurements
We studied 533 children in the CKD in Children (CKiD) Study to determine the prevalence of normotension, isolated BP load elevation (≥25% of all readings elevated but mean BP normal), and ambulatory hypertension. We examined the association between these categories of BP control and adverse outcomes (left ventricular hypertrophy [LVH] or ESKD). We used c-statistics to determine risk discrimination for outcomes by BP load used either independently or in conjunction with other BP parameters.

Results
Overall, 23% of the cohort had isolated BP load elevation, but isolated BP load elevation was not statistically significantly associated with LVH in cross-section (odds ratio, 1.8; 95% CI, 0.8 to 4.2) or time to ESKD (hazard ratio, 1.2; 95% CI, 0.7 to 2.0). In unadjusted cross-sectional analysis, every 10% higher systolic BP load was associated with 1.1-times higher odds of LVH (95% CI, 1.0 to 1.3), but discrimination for LVH was poor (c=0.61). In unadjusted longitudinal analysis, every 10% higher systolic BP load was associated with a 1.2-times higher risk of ESKD (95% CI, 1.1 to 1.2), but discrimination for ESKD was also poor (c=0.60). After accounting for mean systolic BP, systolic BP load was not statistically significantly associated with either LVH or ESKD. Findings were similar with diastolic BP load.

Conclusions
BP load does not provide additive value in discriminating outcomes when used independently or in conjunction with mean systolic BP in children with CKD.

Podcast
This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2020_03_11_CPOD10130819.mp3
EFFECTIVENESS OF COMBINATION OF FEED FORM CAKE AND FEED NATURAL SILK WORMS (TUBIFEX SP) ON FEED CONVERSION RATIO (FCR), SPECIFIC GROWTH RATE AND GIANT FRESHWATER PRAWN SURVIVAL (MACROBACIUM ROSENBERGII) LARVAL STAGE
Authors: Sutarjo Ganjar Adhywirawan 
Published: March 2020

This study aimed to determine the effectiveness of the combination of cake feed and silk worm feed on feed coneration ratio (FCR), Survival, and specific growth rate (SGR) of prawn larvae (Macrobacium rosenbergii). The research was conducted on 8 February - 9 March 2018 at the Fisheries Laboratory of University of Muhammadiyah Malang. Shrimp used in this study is larval prawns stadia larvae. This research was conducted by experimental method using randomized block design (RAL) with 5 treatments and 4 replications. P1 100% silk worm and 0% cake feed, P2 25% silk worm and 75% cake form feed, P3 50% silk worm and 50% cake form feed, P4 75% silk worm and 25% cake feed, P5 100 % feed cake form. Feed is given in ad-station for 40 days. Observed data include Feed coneration ratio (FCR), Survival, specific growth rate (SGR), and water quality. The results showed that the combination of cake feed and silk worm feed had a significant effect on the growth rate of Specific (SGR) Fcount 7.58> from F. Table 5% (3.06) 1% (4.89), While no effect For Figures F count 0.90 <of F. Table 5% (3.06) 1% (4.89) and Feed Converation Ratio as F count 2.23 <of F. Table 5% (3.06) 1 % (4.89). Water quality on maintenance media against a reasonable range for shrimp cultivation. Keywords: fish cake, silk worm, giant freshwater prawn, growth
The influence of difference temperature against the rate of embryonic development and larval abnormality of Cantik Grouper (Epinephelus sp.)
Authors: Simbolon Aprisianus Julkarman , Sutarjo Ganjar Adhywirawan , Hariyadi Hariyadi 
Published: March 2020

Cantikgrouper is the hybridization results grouper or cross-breeding between Epinephelus fuscoguttatus as a female and Epinephelus microdon as a male. The main barriers faced in the development of this commodity is still low levels of spawning up to seeding grouper. Based on the background, this study aimed to investigate optimum temperature observations against the rate of embryonic development Epinephelus sp.larvae. This study used the results of artificial spawning eggs.The fertilized eggs were incubated on six pieces of the container temperature treatment;each treatment there was repeated three times.The incubation temperature was kept on (A) 21-22°C; (B) 23-24°C; (C) 25-26°C; (D) 27-28°C; (E) 29-30°C; (F) 31-32°C. Results showed that eggswere incubated at a temperature of 21-22 ℃ embryonic development to a halt in the blastula, and temperature 23-24°C stalled on phasemyomere embryos. The low-temperature incubation period lasts a long time. Temperature 25-26°C needed 18 hours 6 minutes by 8.33% abnormality rate. Temperature 27-28°C needed 16 hours to hatch witha degree of abnormality of 7.6%. Temperature 29-30°C needed 15 hours 1 minute for the hatch tothe degree of abnormality of 5.33%. The 31-32°C temperature needed 14 hours 6 minutes to hatch witha degree of abnormality of 17.3%. The limits of tolerance for the incubation of the eggs ofcantik grouper (Epinephelusspp.) were 26-32°C.The best temperature of each treatment were obtained at a temperature of 29-30°C. Based on our results, it concluded that the changing temperature affected how long eggs could hatch.
The influence of concentration liquid waste of tofu production to Daphnia sp cultivation biomass
Authors: Mujtahidah Tholibah , Kusuma Baruna 
Published: March 2020

A natural feed of freshwater fish as long as it depends on worms tubifex is hard to be cultivated. Daphnia sp is one of the kinds of Cladocera zooplankton to be an alternative as a natural feed for seed of fish. The liquid tofu waste generally is a problem that is going on in every regional particularly around the Kedu Residency, Central Java. The liquid waste has the nutritional value that can be used for cultivation Daphnia sp. The right concentration of liquid waste tofu to the cultivation of Daphnia sp. has not been studied. This research aimed to find out the influence of concentration out over the density of waste biomass and the visibility of morphology Daphnia sp. The experiment used Complete Randomized Design (CRD) with three treatments and three repetitions, 25:75, 50:50, dan 75:100 (TI, T2, and T3, respectively), tofu liquid waste and water. The results concluded that T3 has repercussions for the density and biomass Daphnia sp. The density of Daphnia sp. was shown by treating 75 % of liquid tofu waste with 31.33 ind L-1 on average and while biomass was 4.6 g L-1 on average. The visibility of Daphnia sp morphology was cultivated with liquid tofu waste compared with Daphnia sp. cultivated using wastewater of catfish cultivation as a control group.Keywords: Biomass, Daphnia sp., Liquid tofu waste, Present of morphology
Analysis and Prediction of Tire Cornering Properties for Different Inflation Pressures Based on Deflection Control
Authors: Sun Lihong , Lu Dang , Li Bing , Suo Yanru , Xia Danhua 
Published: March 2020

ABSTRACT
The variation of inflation pressure has an important effect on the mechanical characteristics of tires that can affect vehicle performance, so the influence of inflation pressure should be taken into account in high-precision tire models. Much research has focused on tire mechanical characteristics under different inflation pressures and modeling methods, such as the Improved Magic Formula/Swift Tire model developed by Schmeitz et al. that takes inflation pressure into account. Based on a large number of tire testing data under different inflation pressures, an empirical model can be obtained, but numerous tire tests are expensive and cannot reveal the mechanism. In previous studies, most tire tests were based on load control, wherein the load is constant while the footprint, carcass, and belt stiffness can change with the variation of inflation pressure, making the cornering characteristics much more complicated. Herein, a method of deflection control is used and the contact patch is well maintained. The effect of tire inflation pressure is simplified to be the change of structure stiffness and averaged contact pressure. The effect of inflation pressure on cornering properties under deflection control is systematically observed under different tire deflection values. In addition, a prediction model extended from the Magic Formula model is proposed. The model of Schmeitz et al. [1,2] needs test data from at least three inflation pressures; the model proposed herein requires tests at only two inflation pressures. The validation shows that this prediction method has good accuracy, almost the same as that of the model of Schmeitz et al. The error index of the lateral force is at most 2%, and the error index of the self-aligning torque is 4% at the maximum.
The implementation of national projects and the development of the construction industry
Authors: Пешков Виталий 
Published: March 2020

Russia’s “national projects”, intend to provide large-scale investments in human development and improving the well-being of the country’s citizens. The Russian government has published information on its website about all the 12 National Projects, which are going to be implemented up until late 2024.
He work on these projects is aimed at providing breakthrough scientific-technological and socio-economic development for Russia, increasing the standard of living, creating conditions and opportunities for personal fulfillment and unlocking every person’s talent.
The largest number of goals, or almost 20%, constitutes measures on infrastructure development, particularly regional road networks.
To boost the construction sector, the government planned to extend the use of bank loans, not specifying the source of infrastructure mortgages.
Peningkatan Mutu Sarana Pendidikan Melalui Pengembangan Self Access Library For English Students (SALE)
Authors: Hidayati Fithriyah Nurul , Fatmawati Nor Laili 
Published: March 2020

<p><em>The research and development of Self Access Library for English Studets (SALE) is aimed at increasing the quality of educational tools as mandated by Permenristekdikti RI No. 44 2015 and its change Permenristekdikti RI No. 50 2018 about National Standard of Higher Education (SN Dikti). It is conducted based on the need of students of PBI IAIN Surakarta for comprehensive, accurate, easily accessible and inexpensive learning sources. Thus, SALE is initiated as an online library providing 126 English e-books classified based on the syllabus of PBI, covering the topics on English education, linguistics ang literature so the students can find appropriate learning sources easily. SALE also gives the students connections to some experts so they can meet virtual consultants or discussion partners to confirm their reading comprehension on the issues concerned. The research and development include some steps; observing potential problems, collecting data, designing SALE, validating the product by experts, first revision, small group trial, second revision, user trial, packaging, and final product. The score of validation by the experts and small group trial shows that SALE is categorized very good and eligible. It means SALE is ready to be an alternative learning source provider with qualified long distance service. The use of SALE by the students causes the improvement on students’ tasks quality as the result of an easy access to some important references appropriate with their majors. Therefore, SALE has become an evidence of the efforts to improve the quality of educational toools at IAIN Surakarta, particularly at PBI department</em></p>
Aproximações e distanciamentos dos conceitos de gás e vapor nos livros didáticos de química aprovados no PNLEM 2018
Authors: Costa Jaqueline Da Silva , Lima João Paulo Mendonça , Sarmento Victor Hugo Vitorino 
Published: March 2020

O livro didático tem sido a principal ferramenta utilizada na preparação e execução das aulas, funcionando como guia curricular para discentes e docentes. Em virtude disso, esse material deve ser constantemente analisado. Um dos assuntos da matriz curricular de Química que pode ser analisado é o de gás e vapor. Estes termos já foram confundidos como sinônimos, mas atualmente sabe-se que possuem diferenças. Com isso, o presente trabalho teve por objetivo analisar os distanciamentos e aproximações dos conceitos de gás e vapor nos livros didáticos aprovados no Programa Nacional do Livro didático para o Ensino Médio 2018 (PNLEM 2018) em relação à Ciência de Referência (estudos de Thomas Andrews). Utilizando a ferramenta de análise proposta por Franzolin (2007) observou-se que dos seis livros aprovados no PNLEM 2018, apenas três trouxeram essa discussão. Esses três livros aproximaram-se do referencial adotado. Além disso, foi possível associar a ausência dessa discussão em alguns dos livros analisados em virtude da escassez dessa abordagem nos livros de Ensino Superior, visto que estes são referência na elaboração do material didático do Ensino Básico. Sendo assim, por meio deste trabalho, destacou-se a importância do profissional da educação em identificar as potencialidades e limitações do livro didático.
Palavras-Chave: Livro didático, Ensino de Química, Gás e vapor.
SOĞUK SAVAŞ SONRASI RUSYA FEDERASYONU İÇ GÜVENLİK BİRİMLERİ
Authors: İÇEN Ahmet Burak 
Published: March 2020

Bu
makalede Soğuk Savaş sonrası modern Rusya’nın iç güvenlik aktörleri ayrı ayrı
incelenmiş, yapısal ve kurumsal özellikleri haricinde daha anlaşılabilir olması
adına ülkemiz muadil kurumlarıyla karşılaştırmaları yapılmıştır. Rusya
Federasyonu kapladığı milyonlarca kilometrekare toprağı ve bu topraklar
içerisinde yaşayan çok çeşitli halkları ile zor ve büyük bir coğrafyada iç
güvenlik ve iç asayişi sağlamaya çalışmaktadır. Böylesine farklı halkları bir
arada geniş bir coğrafyada barındırmak örgütsel ve mali olarak oldukça zor bir
iş haline gelmiş, soğuk savaş sonrası Sovyetler Birliğinin yıkılması üzerine
temelinden sarsılan düzen, yeni bir devlet anlayışı içerisinde yapılanma
zorunluluğu getirmiştir. İç karışıklıklar ve ekonomik buhranlar yapılanmanın
yavaşlamasına neden olmuş, iç güvenlik sorunu uzun yıllar boyunca Rusya’nın en
önemli sorunu olmuştur. Putin dönemine kadar yeniden yapılanma ile rol model
kapsamında yetersiz kalınmış ve Sovyetler geleneği hissedilmeye devam etmiştir.
Ancak Putin dönemi ile Çarlık Rusya’sı devlet düzeni incelenmiş ve Çarlık
Rusyası-Sovyetler sentezi ile kendine özgü bir iç güvenlik anlayışı ve bu
anlayış üzerine yapılanan kurumlar ortaya çıkmıştır. Makalede, yeniden
yapılanan iç güvenlik organlarının yapısal, işlevsel yönleri ele alınmış,
Türkiye’deki muadilleri ile karşılaştırılması amaçlanmıştır.
In silico library design, screening and MD simulation of COX-2 inhibitors for anticancer activity
Authors: Sahu Ankita , Pradhan Dibyabhaba , Raza Khalid , Qazi Sahar , Jain A K , Verma Saurabh 
Published: March 2020

Health problems are increasing worldwide pertaining to cancer modalities.Cyclooxygenase enzyme is known to be involved in cancer biology, neurological disorders, cardiovascular and other diseases. It has been a promising target for developing novel anti-inflammatory drugs in breast cancer treatment. Hence, a computer-aided drug design strategy was applied to identify potent inhibitors of the COX-2 receptor. For this purpose, 12084 ligands from different databases to be tested based on similarity search criteria and were docked against our target protein COX-2 retrieved from the protein data bank. The high-throughput virtual screening protocol was performed and examined the compounds for its binding free energies. Eleven compounds were found out with better binding affinity by virtual screening results and showed interaction with the protein at the known active site. The selected compounds filtered through the Lipinski’s rule of five. The physicochemical properties and bioactivity scores were calculated. Molecular docking calculations, MD simulations, ADMET properties, and protein-ligand interaction were analyzed to determine the suitability of each ligand. Overall, the results from our study suggest that compound ZINC000039428234 could be a potent inhibitor for the COX-2 protein of breast cancer. We look forward to this result is of the enormous key in designing a potential drug candidate for breast cancer.
Propulsion System Design For The Indonesian Semi High Speed Train
Authors: Shalahuddin Lukman , Putranto Kartiko E. , Eskayudha Dimas B. 
Published: March 2020

This paper describes a study on the development of methodology to select the most appropriate technology, and the most optimum design and configuration for the propulsion system of the semi-high speed intercity train that will be operated on the Jakarta-Surabaya corridor. It also describes the method to calculate resistance loads Â and tractive forces and hence the power required to propel the train along the specified route within targeted time. Among the output of this study is a recommendation for the most optimum propulsion system with basic/ main parameters for main components such as diesel engine, traction motor and the possibility of Diesel Electric Multiple Unit (DEMU) Hybrid battery system.
Epizodisták főszerepben – a szenvedélybetegek testvérei
Authors: Gyárfás Anikó 
Published: March 2020

A tanulmány a szenvedélybetegek testvéreivel foglalkozik. A szakirodalmi áttekintés alapján a szenvedélybetegek szüleiről, párjukról sok kutatás készült, testvéreikről viszont kevés. A tanulmány célja ennek a hiánynak a pótlása. A kutatás során a Kék Pont Alapítvány szerhasználók testvérei számára szervezett csoportjából öt, továbbá egy, nem csoporttag testvérrel készítettem félig strukturált interjút. Az interjúkat irányított tematikus elemzéssel dolgoztam fel.
Eredmények: a testvérek családon belüli kapcsolatait negatívan befolyásolja hozzátartozójuk szerhasználata. A testvérek a droghasználatot minden esetben jóval előbb tudják, mint a szülők. Túlzott felelősséget vállalnak szerhasználó hozzátartozójuk megmentéséért. A testvérek iskolai, munkahelyi teljesítményét, mindennapi helytállását kedvezőtlenül befolyásolta hozzátartozójuk szerfüggősége.
Következtetések: fel kívánom hívni a szakemberek és a szülők figyelmét arra, hogy a nem szerhasználó testvérek számára is nyújtsanak segítséget.
Point-of-care ultrasonography: training, applications and barriers. A survey study
Authors: Shrestha Gentle S. , Acharya Subhash P. , Shrestha Pramesh S. , Shrestha Ninadini , Paneru Hem R. , Paudel Sharma , Lohani Benu , Pradhan Saurabh , Aryal Diptesh , Bista Navindra , Shah Bindu L. , Bhattarai Amit S. , Parajuli Bashu D , Koirala Megha , Acharya Pragya , Koirala Sabin , Amatya Ashish G. , Bhandari Sandip , Gurung Arjun , Shrestha Bibhush , Sigdel Shailendra , Shakya Bigen M. , Keyal Niraj , Thakur Anand , Sharma Achyut , Bajracharya Tamanna 
Published: March 2020

Background and Aims: Use of point-of-care ultrasound (POCUS) in acute care setting has rapidly increased and has potentials to guide patient management. This survey study aims to explore the usefulness of a one-day workshop and to elicit the perceived barriers for effective use of POCUS.
Methods: A total of 169 doctors who had attended one day Acute Care Ultrasound workshop were approached through email. Online link to access the survey created using Google forms was sent. The survey contained questions related to the details about the participants, feedback about the workshop, whether the workshop has helped to change the practice of the participants, availability of ultrasound machine during the daily practice and the perceived barriers for use of POCUS.
Results: A total of 41 responses were obtained. Majority of the participants had anaesthesiology as the base specialty followed by general practice. Most of them had ICU as their predominant working place, followed by emergency room and operating room. The workshop was found to be helpful by most of the participants. Majority of the participants (20 participants; 49%) had ultrasound machine sometimes available during their daily practice. Only 20% (8 participants) had ultrasound machine always available during their clinical practice. Similarly, 46% (19 participants) considered lack of access to ultrasound machine as a barrier for application of POCUS. Significant number of participants considered lack of supervision and guidance (18 participants; 44%) and lack of knowledge and skills (13 participants; 32%) as the barriers.
Conclusions: Majority of the participants found the one-day workshop helpful. Doctors from various specialty, working in acute care setting had participated in the survey. Limited access to ultrasound machine, together with lack of adequate knowledge and skills were perceived as major barriers for effective use of point-of-care ultrasound.
REVITALISASI KEPEMIMPINAN KOLEKTIF-KOLEGIAL DALAM MEMBANGUN EFEKTIFITAS KOMUNIKASI ORGANISASI PESANTREN (STUDI INTERAKSIONISME SIMBOLIK DI PONDOK PESANTREN JOMBANG)
Authors: Pramitha Devi 
Published: March 2020

Dewasa ini kepemimpinan pesantren yang terjadi tidak lagi menerapkan kepemimpinan tunggal, dan organisasi pesantren pun telah dimasukkan dalam bentuk yayasan. Dengan gejala baru ini, maka organisasi pesantren menjurus kearah impersonal, tanpa mengurangi peranan kiai sebagai pemimpin tertinggi, maka kepemimpinan mengarah pada pola kolektif, sesuai dengan hierarkhi kepemimpinan sebuah organisasi yayasan. Dalam penelitian ini ada dua masalah yang ingin diteliti, yaitu: (1) perilaku kepemimpinan kolektif-kolegial; dan (2) Model komunikasi organisasi pesantren ditinjau dari teori interaksionisme simbolik; di PP Bahrul Ulum Tambakberas dan PP Mambaul Maarif Denanyar Jombang. Penelitian ini menggunakan pendekatan penelitian kualitatif dan jenis penelitiannya adalah fenomenologi dengan menggunakan rancangan interaksionisme simbolik. Data diperoleh dengan wawancara (interview), dokumen-dokumen (documents) dan observasi (observation). Analisis data menggunakan model Spradley yang mengambil salah satu dari analisis yaitu analisis domain. Ada dua hasil temuan yang diperoleh, yaitu, Pertama, perilaku kepemimpinan kolektif-kolegial di PPBU Tambakberas Jombang adalah: (1) partisipatif-demokratis, sedangkan di PPMA Denanyar Jombang adalah (2) partisipatif-konsultatif. Kedua, Ada dua model komunikasi organisasi yang diterapkan baik di PPBU Tambakberas Jombang maupun di PPMA Denanyar Jombang yaitu, Komunikasi yang bersifat “top-down” dan komunikasi yang bersifat “buttom-up”.