bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution patterns and biogeography of Sargassum (Fucales, Phaeophyceae) along the coast of Vietnam
Authors: Nguyen Tu Van , Boo Sung Min 
Published: July 2020

Abstract

Sargassum species form large beds that play an important role in coastal ecosystems. The beds are abundant and Sargassum is often used as food and in Asian medicine in Vietnam. As a base for future use and conservation, we surveyed 14 species of Sargassum at eight locations during April-May of 2018 and 2019. Sargassum species from Vietnam were divisible into northern and southern groups; the northern group comprised Sargassum graminifolium, Sargassum herklotsii, and Sargassum cotoense, which occur in the North and North Central zones. The southern group comprised Sargassum bicorne, Sargassum feldmannii, Sargassum ilicifolium, Sargassum swartzii, and two endemic species, Sargassum phamhoangii and Sargassum quinhonense, which occur in the Central to South West zones. Three species, Sargassum aquifolium, Sargassum oligocystum, and Sargassum polycystum, were widespread along the long coast of Vietnam. This is the first report on distribution patterns of Sargassum species along the long coast of Vietnam. Our study provides baseline data for evaluating ecological disturbance and risks of Sargassum-associated ecosystems.
Managing COVID-19 outbreak in Nigeria: matters arising
Authors: Onyeaghala Augustine Anayochukwu , Olajide Isiramen 
Published: July 2020

Abstract
Severe Acute Respiratory Syndrome – novel Coronavirus 2 (SARS-nCoV-2), was first reported in Wuhan, China, in December, 2019. Since the outbreak, the virus has infected more than 9,866,685 individuals, 4,983,029 treated and discharged and 495,692 deaths globally. The first Coronavirus Disease 2019 (COVID-19) in Nigeria was imported in February, 2020 and since then community transmission has been prevalent. As at the time of writing this report, Nigeria has reported about 23,298 cases of COVID-19, 8,253 treated and discharged and 554 deaths, giving a case mortality ratio of 2.4%. While responsible government agencies and international partners have been working hard to curtail the spread of the disease, we present in this report, some matters arising from managing COVID-19 pandemic in Nigeria; and proffered suggestions which could help not only in managing the current COVID-19 pandemic, but also for winning future outbreaks of public health significance with a view to curtailing global health security.
Hemoglobin variants in southern China: results obtained during the measurement of glycated hemoglobin in a large population
Authors: Xu Anping , Chen Weidong , Xie Weijie , Wang Yajun , Ji Ling 
Published: July 2020

Abstract

Objectives
Hemoglobin (Hb) variant is one of the most common monogenic inherited disorders. We aimed to explore the prevalence and hematological and molecular characteristics of Hb variants in southern China.

Methods
We collected blood samples from all patients with suspected variants found during HbA1c measurement via a cation-exchange high-performance liquid chromatography system (Bio-Rad Variant II Turbo 2.0) or a capillary electrophoresis method (Sebia Capillarys). Hematological analysis, Sanger sequencing, and gap-PCR were performed for these samples.

Results
Among the 311,024 patients tested, we found 1,074 Hb variant carriers, including 823 identified using Capillarys and 251 using Variant II Turbo 2.0, with a total carrier rate of 0.35%. We discovered 117 types of Hb variants (52 HBB, 47 HBA, and 18 HBD mutations) containing 18 new mutations. The most common variant found was Hb E, followed by Hb New York, Hb J-Bangkok, Hb Q-Thailand, Hb G-Coushatta, Hb G-Honolulu, Hb G-Taipei, and Hb Broomhill. Most heterozygotes for the Hb variant exhibited normal hematological parameters. However, most patients with compound heterozygotes for the Hb variant and thalassemia showed varied degrees of microcytic hypochromic anemia.

Conclusions
The prevalence of hemoglobin variants remains high and exhibits genetic diversity and widespread distribution in the population of southern China.
Geometrical analysis of architectural drawnings in the Shah-mosque Isfahan
Authors: Goudarzi Masoumeh , Bemanian Mohammadreza , Leylian Mohammadreza 
Published: July 2020

Abstract
The golden number has been one of the most important measures of beauty from ancient Greece till now. Although the reason still unclear, it is certain that the golden ratio has a direct correlation with beauty. This nice feeling can come from listening to a musical piece or watching a visual art, which is based on this wondrous number. Although the golden number is more suitable from beauty or harmony’s perspective, for some researches it is a requirement to develop Architectural designs. Therefore, in this article a masterpiece (Shah-mosque Isfahan) was investigated to find its golden relations. This mosque was chosen because of the precise and harmonious proportions. In this research: plan, sections, facade and decorations of ceiling tiles in main dome, were analyzed by Phi-matrix software in which, existence of the golden ratio has been proven undoubtedly.
Numerical Analysis of a Stable Finite Volume Scheme for a Generalized Thermistor Model
Authors: Ghilani Mustapha , Quenjel El Houssaine , Rhoudaf Mohamed 
Published: July 2020

Abstract
A generalized thermistor model is discretized thanks to a fully implicit vertex-centered finite volume scheme on simplicial meshes.
An assumption on the stiffness coefficients is mandatory to prove a discrete maximum principle on the electric potential.
This property is fundamental to handle the stability issues related to the Joule heating term.
Then the convergence to a weak solution is established.
Finally, numerical results are presented to show the efficiency of the methodology and to illustrate the behavior of the temperature together with the electric potential within the medium.
Language change and language evolution: Cousins, siblings, twins?
Authors: Hartmann Stefan 
Published: July 2020

AbstractThe relationship between “language change” and “language evolution” has recently become subject to some debate regarding the scope of both concepts. It has been claimed that while the latter used to refer to the language origins in the first place, both terms can now, to a certain extent, be used synonymously. In this paper, I argue that this can partly be explained by parallel developments both in historical linguistics and in the field of language evolution research that have led to a considerable amount of convergence between both fields. Both have adopted usage-based approaches and data-driven methods, which entails similar research questions and similar perspectives on the phenomena under investigation. This has ramifications for current models and theories of language change (or evolution). Two approaches in particular, the concept of complex adaptive systems and construction grammar, have been combined in integrated approaches that seek to explain both language emergence and language change over historical time. I discuss the potential and limitations of this integrated approach, and I argue that there is still some unexplored potential for cross-fertilization.
Wettability of welded wood-joints investigated by the Wilhelmy method: part 2. Effect of wollastonite additive
Authors: Vaziri Mojgan , Karlsson Olov , Abrahamsson Lars , Moghaddam Maziar Sedighi , Sandberg Dick 
Published: July 2020

AbstractThe effect of wollastonite on the wetting properties of welded Scots pine-joints was studied using the multicycle Wilhelmy plate method and by observation of the chemical composition of the welded joints. Welding pine with wollastonite for 5 s resulted in a decrease in the water uptake and the swelling, and an increase in the contact angle of the welded joint compared to welded wood without wollastonite. High-performance liquid chromatography and gas chromatography/mass spectrometry showed the presence of dehydration products such as furfural, 5-hydroxymethylfurfural, and levoglucosan in methanol extracts from welded joints of specimens welded with and without wollastonite. Phenols were also found by analysis using the Folin-Ciocalteu method and High-performance liquid chromatography. The importance of such compounds in relation to the wetting properties of the welded joint is discussed.
On quasiprimitive edge-transitive graphs of odd order and twice prime valency
Authors: Liao Hong Ci , Li Jing Jian , Lu Zai Ping 
Published: July 2020

Abstract
A graph is edge-transitive if its automorphism group acts transitively on the edge set.
In this paper, we investigate the automorphism groups of edge-transitive graphs of odd order and twice prime valency.
Let

Γ

{\varGamma}

be a connected graph of odd order and twice prime valency, and let G be a subgroup of the automorphism group of

Γ

{\varGamma}

.
In the case where G acts transitively on the edge set and quasiprimitively on the vertex set of

Γ

{\varGamma}

, we prove that either G is almost simple, or G is a primitive group of affine type.
If further G is an almost simple primitive group, then, with two exceptions, the socle of G acts transitively on the edge set of

Γ

{\varGamma}

.
Inverse spectral problem of an anharmonic oscillator on a half-axis with the Neumann boundary condition
Authors: Khanmamedov Agil K. , Gafarova Nigar F. 
Published: July 2020

AbstractAn anharmonic oscillatorT⁢(q)=-d2d⁢x2+x2+q⁢(x){T(q)=-\frac{d^{2}}{dx^{2}}+x^{2}+q(x)}on the half-axis0≤x<∞{0\leq x<\infty}with the Neumann boundary condition is considered. By means of transformation operators, the direct and inverse spectral problems are studied. We obtain the main integral equations of the inverse problem and prove that the main equation is uniquely solvable. An effective algorithm for reconstruction of perturbed potential is indicated.
Tumor-induced rickets-osteomalacia: an enigma
Authors: Kumar Sandeep , Shah Ravikumar , Patil Virendra , Ramteke-Jadhav Swati , Bal Munita , Lila Anurag , Shah Nalini , Bandgar Tushar 
Published: July 2020

Abstract

Objectives
We report a case of pediatric thoracic tumor-induced osteomalacia (TIO) causing severe hypophosphatemic rickets with delayed diagnosis and emphasize on timely management of this rare entity.

Case presentation
A young boy presented with rickets since five years of age. Biochemical evaluation revealed hypophosphatemia, hyperphosphaturia, elevated alkaline phosphatase and normal calcium levels. Initially managed as hereditary hypophosphatemic rickets, he was given phosphorus supplements and calcitriol. Despite the therapy, skeletal deformities worsened requiring surgical corrections. Subsequently, he developed iatrogenic tertiary hyperparathyroidism for which he underwent total parathyroidectomy. Later on, he was found to have fibroblast growth factor-23 secreting thoracic mass (10.5 cm in largest dimension) which was excised with significant post operative improvement. Histopathology showed phosphaturic mesenchymal tumor-mixed connective tissue variant, confirming the diagnosis of TIO.

Conclusion
TIO, a correctable cause of hypophosphatemic rickets, should be considered in children presenting with hypophosphatemic rickets with evident mass on examination/imaging and in refractory cases.
Survey on clinical use and non-use of recombinant human erythropoietin in European neonatal units
Authors: Bolte Katharina , Maier Rolf F. 
Published: July 2020

AbstractObjectivesRecombinant human erythropoietin (rhEPO) has been shown to effectively and safely prevent the anemia of prematurity and to reduce the transfusion need in very low birth weight (VLBW) infants and has been licensed for this indication in Europe in 1997. The objective of the study was to obtain information on the use or non-use of rhEPO in neonatal units in Germany and other European countries.MethodsAnonymized 14-questions web-based questionnaire.ResultsSeventy-nine questionnaires from Germany and 63 questionnaires from other 15 European countries were completed. Of the responders, 39% indicated to use rhEPO routinely or occasionally in VLBW infants, whereas 61% responded to never use rhEPO in this population. The major reasons given for non-use were lack of recommendation in national guidelines (69%) and/or doubt about efficacy of rhEPO to reduce transfusion need (53%). Twenty-seven percent of the responders indicated to use rhEPO for neonates with birth weights above 1,500 g. Neuroprotection in VLBW infants (26%) and hypoxic ischemic encephalopathy in term neonates (27%) were given as indications for off label use of rhEPO.ConclusionsThis survey indicates that rhEPO is used for the anemia of prematurity as licensed in less than half of neonatal units in Germany and other European countries. On the other hand it seems to be used off label in neonates for neuroprotection in a considerable number of units although there is no final evidence on its neuroprotective effects.
Crystal structure of tert-butyl 2-(hydroxymethyl)-5-{4-[(methoxycarbonyl)amino]phenyl}-2,5-dihydro-1H-pyrrole-1-carboxylate, C18H24N2O5
Authors: Caracelli Ignez , Zukerman-Schpector Julio , Garcia Ariel L. Llanes , Costenaro Edson R. , Correia Carlos Roque D. , Tiekink Edward R.T. 
Published: July 2020

Abstract
C18H24N2O5, monoclinic, P21/c (no. 14), a = 11.4784(7) Å, b = 9.0180(8) Å, c = 17.9483(17) Å, β = 92.823(7)°, V = 1855.6(3) Å3, Z = 4, R
gt(F) = 0.0505, wR
ref(F
2) = 0.1611, T = 293 K.
The investigation effect of weight loss on serum vaspin, apelin-13, and obestatin levels in obese individual
Authors: Can Figen Cansu , Noyan Tevfik , Özdemir Özlem 
Published: July 2020

Abstract

Objectives
It was aimed to investigate if there were any significant corresponding changes on adipokine levels in obese subjects who achieved a 10% reduction in body weight.

Methods
Thirty obese and 25 healthy adults were enrolled in present study, and serum levels of vaspin, apelin-13, obestatin, and insulin were determined with the ELISA method.

Results
The serum obestatin and apelin-13 values of the obese group obtained as basal and after weight loss was significantly lower than in controls (p<0.05, p<0.01, p<0.01, p<0.05, respectively); however, weight loss did not cause significant changes on these parameters in obese groups (p>0.05). The vaspin level did not differ between the groups (p>0.05). The obese group had characterized increased serum insulin and insulin resistance assessment by the homeostatic assay (HOMA-IR) levels compared to controls (p<0.01, p<0.05, respectively); also, weight loss caused a significant decrease in these parameters compared to basal levels (p<0.01). No significant correlation was detected among the vaspin, apelin-13 and obestatin levels in the obese group (p>0.05).

Conclusions
Obese individuals exhibited decreased levels of apelin-13 and obestatin. Moreover, 10% weight loss caused a significant reduction of insulin resistance, but no significant change was detected on apelin-13, obestatin, and vaspin levels.
Effect of hemolysis on prealbumin assay
Authors: Güven Berrak , Tekin Abdülkadir , Can Murat 
Published: July 2020

Abstract

Objectives
Hemolysis is a common problem causing interference on biochemical assays. In this study, we investigated the effect of in vitro hemolysis on the measurement of prealbumin, using normal and low prealbumin concentrations.

Methods
Serum pools containing normal and low levels of prealbumin were spiked with different dilutions of the hemolysate, which was prepared according to the classical osmotic shock procedure. The final concentrations of hemoglobin in the samples were 10.63, 6.25, 5.31, 2.66, 1.33, 0.66, 0.33 and 0 g/L. The prealbumin levels in these samples were analyzed for three times by the immunoturbidimetric method on AU680 clinical chemistry analyzer. Mean percent changes of prealbumin results were presented with interferographs.

Results
We observed that hemolysis interfered negatively with both normal and low level serum pools. This effect began to exceed the limit of 10% as a critical point in the concentration range 5.31 to 6.25 g/L hemoglobin concentration in both normal and low serum pools. The limit exceeding value was higher in the low serum pool than the normal serum pool (20% and 11%, respectively).

Conclusions
Clinical laboratories must be alert the effect on low prealbumin levels, especially in settings where hemolysis is an increasing problem.
The method comparison and the verification of precision of Mindray CL-6000i thyroid function tests (TFTs)
Authors: Bozkaya Giray , Şişman Ali Rıza 
Published: July 2020

Abstract

Objectives
Thyroid diseases are the most frequent endocrine disorders and thyroid function tests (TFTs) are the most commonly requested endocrine tests. The reliable measurements of these tests are quite important. The aim of our study was to determine the bias and to verify the precision of the newly introduced Mindray CL-6000i immunoassay system in the guidance of CLSI guidelines.

Methods
A precision and bias study was performed in Mindray CL-6000i analyzer for FT3, FT4, TSH, Anti-TG, and Anti-TPO tests by using BioRad quality control (QC) materials and serum samples, respectively. Bland–Altman difference plot and Passing-Bablok regression analysis was made for method comparison with Beckman Coulter DXI 800 analyzer.

Results
The repeatability coefficient of variations (CVs) of FT3, FT4, TSH, Anti-TG, and Anti-TPO tests were ≤2.36, ≤1.66, ≤2.38, ≤3.48, and ≤3.31% while within laboratory CVs were ≤2.85, ≤4.61, ≤2.59, ≤3.78, and ≤3.60%, respectively. The mean differences between the two methods obtained from Bland–Altman analysis for FT3, FT4, TSH, Anti-TG, and Anti-TPO were defined to be −19%, 1.95%, −5.9%, −3.5%, and 7.3%, respectively.

Conclusions
Mindray CL-6000i had good precision in all tests, but the difference between the two methods in some tests shows that the harmonization and standardization of TFTs initiated globally is required.
SONA: A relational methodology to identify structure in networks
Authors: Glückler Johannes , Panitz Robert , Hammer Ingmar 
Published: July 2020

AbstractThe study of networks has been characterized by a dualism of methods. Researchers either use interpretive methods to explore the quality of social relations, or quantitative methods to assess the formal structure of network connectivity. However, because relational and structural characteristics of networks are interdependent, we present a method for Situational Organizational Network Analysis to overcome this dualism. In sequencing and integrating qualitative, quantitative and action research techniques, SONA is designed to help unveil authentic understandings of socially meaningful structure in compliance with research ethics. Drawing on a decade of research experience we describe the workings of this integrative method and elaborate on its valued-added compared to single methods. Building on selected applications, we demonstrate how the tailored use of SONA enhances cross-validation, supports original theory-building, and empowers reflexive transformative research.
Ultrasonic study of Si-oil based magneto-rheological fluid
Authors: Yadav Chandreshvar Prasad , Pandey Dharmendra Kumar , Singh Dhananjay 
Published: July 2020

Abstract
The present study is devoted to ultrasonic characterization of Si-oil based magneto-rheological (MR) fluid. Initially, the structural, morphological and magnetic properties of carbonyl iron powder have been carried out by its X-ray diffraction (XRD), scanning electron microscope (SEM), SEM-energy dispersive X-ray analyser (SEM-EDX) and vibrating sample magnetometer (VSM) measurements. The cubic structure with lattice parameter 2.841 Å of powdered material is confirmed by XRD study while spherical particle content is confirmed by SEM measurement. The VSM measurement of powder endorses the smooth magnetization and demagnetization with no remnance and coercivity. The rheological and ultrasonic properties are measured for pure Si-oil and four synthesized MR fluids having 10–40 wt% of carbonyl iron powder. The density and viscosity of synthesized MR fluid is found to enhance with weight percentage of carbonyl iron powder. In absence of magnetic field, the longitudinal ultrasonic velocity is found to decay with temperature and concentration. In presence of magnetic field, the longitudinal ultrasonic velocity is found to enhance while velocity measured at transverse magnetic field is found to decay for each MR fluid. The change in ultrasonic velocity with concentration at fixed temperature or magnetic field resembles the magnetization characteristics of disperse powder in MR fluid. The study opens a new dimension for its characterization through ultrasonic non-destructive technique.
Isolation of secondary metabolites from the Iranian medicinal plant Eremurus persicus
Authors: Mottaghipisheh Javad , Kúsz Norbert , Hohmann Judit , Tsai Yu-Chi , Csupor Dezső 
Published: July 2020

Abstract

Eremurus persicus (Jaub. & Spach) Boiss. belonging to Xanthorrhoeaceae family is an endemic medicinal plant widely distributed in Iran. Its leaves have been traditionally used as a food and also as medicinal plant. Regarding the widespread application of E. persicus in Iranian folk medicine, and the insignificant investigation of its components, this study aimed at the isolation and identification of major secondary metabolites of this plant. By applying various chromatographic techniques, corchoionoside A (1), 4-amino-4-carboxychroman-2-one (2), isoorientin (3), ziganein 5-methyl ether (4), auraptene (5), and imperatorin (6) were isolated from the EtOAc and CHCl3 fractions of the crude extract. Except isoorientin (3), all the identified phytoconstituents were reported for the first time from Eremurus genus.
Synthesis, investigation of biological effects and in silico studies of new benzimidazole derivatives as aromatase inhibitors
Authors: Sağlık Begüm Nurpelin , Şen Ahmet Mücahit , Evren Asaf Evrim , Çevik Ulviye Acar , Osmaniye Derya , Kaya Çavuşoğlu Betül , Levent Serkan , Karaduman Abdullah Burak , Özkay Yusuf , Kaplancıklı Zafer Asım 
Published: July 2020

Abstract
Inhibition of aromatase enzymes is very important in the prevention of estrogen-related diseases and the regulation of estrogen levels. Aromatase enzyme is involved in the final stage of the biosynthesis of estrogen, in the conversion of androgens to estrogen. The development of new compounds for the inhibition of aromatase enzymes is an important area for medicinal chemists in this respect. In the present study, new benzimidazole derivatives have been designed and synthesized which have reported anticancer activity in the literature. Their anticancer activity was evaluated against human A549 and MCF-7 cell lines by MTT assay. In the series, concerning MCF-7 cell line, the most potent compounds were the 4-benzylpiperidine derivatives 2c, 2g, and 2k with IC50 values of 0.032 ± 0.001, 0.024 ± 0.001, and 0.035 ± 0.001 µM, respectively, compared to the reference drug cisplatin (IC50 = 0.021 ± 0.001 µM). Then, these compounds were subject to further in silico aromatase enzyme inhibition assays to determine the possible binding modes and interactions underlying their activity. Thanks to molecular docking studies, the effectiveness of these compounds against aromatase enzyme could be simulated. Consequently, it has been found that these compounds can be settled very properly to the active site of the aromatase enzyme.