bluuebunny/crossref_metadata_2025_split huggingface dataset:
How practice in plant collection influences interactions with illustrations and written texts on local plants? Case study from Daghestan, North Caucasus
Authors: Kołodziejska Iwa Urszula , Kaliszewska Iwona Julia 
Published: February 2020

Abstract
Background It is only recently that written sources of local knowledge on plants are not being ignored by scholars as not belonging to “traditional” knowledge. However, usually ethnobotanical texts, if they at all focus on knowledge from written sources, they do not pay attention to the actual processes of interaction with written texts and illustrations. During our research we examined people’s interactions with texts, illustrations and herbarium specimens of plants they collect or are familiar with. We focused on a small community of Shiri people in the mountainous village and in the lowland settlements in the Republic of Daghestan, Russia. In the paper we address the following questions: how do Shiri people interact with illustrations, written text and herbaria specimens? How amount of practice in plant collection influences reading of the texts about plants and looking at illustrations? What are the methodological implications of the ways people interact with illustrations, texts and herbaria specimens? Methods Our research was based on long term ethnographic fieldwork: co-designing of a booklet showing edible plants people collect in Shiri, semi-structured interviews and video-recording and observing interactions between people and text/illustrations/voucher specimens. Results We identified three kinds of interactions between individuals and text/illustrations: “text-wayfaring” – predominantly a bodily interaction between individual and illustrations and text; “fact/spelling checking” – predominantly discursive and information focused; “between wayfaring and fact checking” – the mix of the two above. Using the idea of textual poaching as well as knowledge making approach we show that the way of interacting influences what is acquired from the text/illustrations and how. This process influences reader’s LEK. The mere presence of the information in the text available to people does not imply that they will acquire it, make use of it and change their LEK. Photographs and pressed specimens of locally known plants are often not (or only partly) recognized. Video-recording is essential for analysing the above interactions. Conclusions In ethnobotanical research it is important to pay more attention to people’s interaction with their sources of knowledge, including text and illustrations. Discursive part of LEK is more easily influenced by written sources. Practice of plant collection is not as easily influenced.
Successful treatment with belimumab in a patient with refractory systemic lupus erythematosus after initiation of hemodialysis: Considering the synergistic effect of belimumab and immunological burn-out phenomenon in end stage renal disease patients on hemodialysis
Authors: Ogura Shota , Karasawa Kazunori , Ono Wataru , Ito Ayaki , Seki Momoko , Yamaguchi Yoshiko , Kamizawa Miwa , Tosaka Mai , Ushio Yusuke , Sugiura Naoko , Takabe Tomo , Miyabe Yoei , Iwabuchi Yuko , Akiyama Kenichi , Sato Masayo , Moriyama Takahito , Uchida Keiko , Nitta Kosaku 
Published: February 2020

Abstract
Background: In patients with systemic lupus erythematosus (SLE), disease activity can persist even after initiating dialysis. However, guidelines for the treatment of patients with SLE after dialysis is initiated have not yet been established. Case presentation: We describe the case of a 62-year-old Japanese woman who was diagnosed with SLE at age 12, progressed to end-stage renal disease (ESRD), and initiated hemodialysis for lupus nephritis. However, SLE activity persisted after hemodialysis. Cyclophosphamide and mycophenolate mofetil were administered in addition to prednisolone and immunoadsorption, but this treatment strategy was limited by side effects. The patient was subsequently treated with belimumab, and the activity of SLE decreased rapidly. Conclusions: ESRD patients with SLE show no significant decrease in transitional B cells, and have elevated levels of B-cell activating factor (BAFF). Both transitional B cells and BAFF are important therapeutic targets for belimumab, indicating that patients with ESRD may benefit from belimumab therapy. However, the effects of belimumab may be potentiated in patients with uremia, who may be more susceptible to adverse events such as infections. Patients with SLE who receive belimumab after initiation of hemodialysis therefore require careful follow-up. Here we report the first case of belimumab administration in a patient with SLE after initiation of hemodialysis.
What is the level of uptake of Partner Notification Services in HIV testing in Selected Health Facilities in Muranga County – Kenya; a retrospective Study
Authors: Kariuki Rewel , Rithaa Gilbert Koome , Elvis Oyugi , Gachathi Daniel 
Published: February 2020

Abstract
Background: Identification of people living with HIV is key in HIV prevention and control. Partner Notification service is a World Health Organization backed strategy of reaching out to sexual partners of people diagnosed with HIV for HIV testing. However, its adoption and success rate in Kenya remains unknown. Methods: A cross sectional facility based study was undertaken in five purposively selected health facilities in Muranga County, Kenya. A retrospective review of patient medical records data for HIV positive index clients and their Sexual Partners conducted. Census approach applied to extract data for study subjects from Partner Notification Service registers for the period covering January 2017 to August 2018. Epi Info software was used for data analysis. Results: A total of 183 index clients offered Partner notification services. The mean age of the indexed clients studied was 39(SD ±13.1). Females comprised 64 % of clients studied. Of the 183 indexed clients, 89% accepted the services and elicited 216 sexual partners for tracing. The ratio of elicited sexual partners to index client was 1.3:1. Out of the 216 sexual partners, 77% were reached and tested. A total of 46 [32%] of the sexual partners elicited and traced, tested HIV positive. The most preferred approaches were provider referral (51%) and contract referral (45%). Dual referral (4%) was the least preferred approach. Conclusions: Partner notification services is acceptable and an effective strategy of increasing HIV case identification and raising awareness to exposed sexual partners in low resource countries.
HIV Risk in Female Sex Workers in the Chinese Border Region
Authors: Wang Yuan Yuan , Wilson Amanda , Chen Rusen , Cen Ping , Wang Yuehui , Yao Xing , Wang Tang , Li Shiyue , Yan Hong 
Published: February 2020

Abstract
Background: Female sex workers (FSWs) in Yunnan are a highly vulnerable population to HIV virus. The HIV positive FSWs can then pass onward the HIV transmission via commercial sex. Yunnan is located near the “Golden Triangle” border region, which has the highest HIV/AIDS prevalence rates in China. Method: In order to understanding of the HIV burden and risk in FSWs in the border region of China, semi-structured interviews were conducted between May 2018 and June 2018 with 20 FSWs recruited in Hekou County, Yunnan province, China. Results: Thematic analysis was applied for the data analysis. There were four themes that were actively interpreted from the data, including: Desire for Condom Use, Poor Gynaecological Service Access, Low HIV/AIDS Literacy, and Working Without the Influence. Conclusion: There is an urgent demand for HIV prevention among FSWs and their clients in the Chinese border regions. It is essential for governmental infrastructures to implement practical strategies in terms of HIV prevention for FSWs in China. Keywords human immunodeficiency virus (HIV), female sex workers (FSWs), “Golden Triangle”, China A Brief Summary of Findings Female sex workers (FSWs) in Yunnan are a highly vulnerable population to HIV virus. There is an urgent demand for HIV prevention among FSWs in the Chinese border regions.
Users' perspectives on non-clinical quality of care in public and private primary healthcare in Albania
Authors: Gabrani Jonila , Schindler Christian , Wyss Kaspar 
Published: February 2020

Abstract
Background: Aiming to tackle the rise of non-communicable diseases and an ageing population, Albania is engaged in boosting primary healthcare services and quality of care. The patients’ perspectives on their experience with public and private providers are, however, missing, although their viewpoints are critical while shaping the developing services. Consequently, we analyse perceptions of users of PHC services as it relates to non-clinical quality of care and the association to sociodemographic characteristics of patients and the type of provider. Methods: A facility-based survey was conducted in 2018 using the World Health Organization responsiveness questionnaire which is based on a 4-point scale along eight non-clinical domains of quality of care. The data of 954 patients were analysed through descriptive statistics and linear mixed regression models. Results: Similar mean values were reported on total scale of the quality of care for private and public providers, also after sociodemographic adjustments. The highest mean scores was reported for the domain ‘communication’ (3.75) followed by ‘dignity’ (3.65), while the lowest mean scores were given for ‘choice’ (2.89) and ‘prompt attention’ (3.00). Urban governmental PHC services were rated significantly better than private outpatient clinics in ‘coordination of care’ (2.90 vs 2.12, p < 0.001). In contrast, private outpatient clinics were rated significantly higher than urban PHC clinics in ‘confidentiality’ (3.77 vs 3.38, p = 0.04) and ‘quality of basic amenities’ (3.70 vs 3.02, p < 0.001). For the other domains, no statistically significant differences were observed. ‘Autonomy’ was reported as least important attribute of quality. Enrolment in health insurance was a predictor of higher quality ratings (coefficient = 0.06, p = 0.02). Conclusion: While the perception of non-clinical care quality was found to be high and similar for public and private providers, promptness and coordination of care require attention to meet patient’s expectations on good quality of care. There is a need to shift from a ‘paternalistic’ model to a ‘co-managing the illness’, raising awareness on autonomy.
Outcomes of a 12-month patient-centred medical home model on patient activation and self-management behaviours among primary care patients presenting with chronic diseases in Sydney, Australia.
Authors: John James , Tannous Kathy , Jones Amanda 
Published: February 2020

Abstract
Background: Patient activation is an important precursor not only for effective self-management of chronic comorbidity but also to empower patients in actively making decisions concerning their health. Studies report that increased activation in terms of high patient activation measure (PAM) scores are associated with increased patient engagement with the health care system, better compliance to treatment protocols, and improved health outcomes. This study aims to evaluate outcomes of Patient-Centred Medical Home model called ‘WellNet’ on activation levels of patients with multimorbidity in general practices across Sydney, Australia. Methods: A total of 636 patients consented to participate in the WellNet program delivered across six general practices in Northern Sydney, Australia. The WellNet treatment comprised of a team-based care with General Physicians collaborating with trained Chronic Disease Management care coordinators. After a comprehensive assessment, the care team designed patient-tailored care plan with self-management support and care navigation according to the level of risk and health care needs. Level of patient activation was measured using the validated PAM 13-item scale at baseline and follow-up. A case-series design was employed to determine significant differences between baseline and 12-months using General Linear Models. Multiple imputation was used to compute missing follow-up scores using Markov Chain Monte Carlo (MCMC) algorithm known as fully conditional specification (FCS). Multivariate regression models were employed to identify significant predictors of activation at follow-up. Results: Of the 626 patients, 420 reported their PAM levels at follow-up. The adjusted model showed significant mean difference in PAM scores of 6.5 (95%CI 5.0-8.1; p-value<0.001) after controlling for baseline covariates. Multivariate regression models determined that older age (OR = -0.14; 95% CI -0.28, -0.01), baseline activation score (OR = 0.48; 95% CI 0.37, 0.59), and private insurance (uninsured patients) (OR = -3.41; 95% CI -6.50, -0.32) were significant predictors of patient activation at follow-up. Conclusion: The WellNet study is the first of its kind in Australia to report on changes in the activation and self-management among patients with multimorbidity. PCMH has the potential to improve patient activation and engagement which can lead to long-term health benefits and sustained self-management behaviours.
Differences in patient population and service provision between nurse practitioner and general practitioner consultations in Swiss primary care: a case study
Authors: Gysin Stefan , Meier Rahel , Vught Anneke van , Merlo Christoph , Gemperli Armin , Essig Stefan 
Published: February 2020

Abstract
Background Primary care systems around the world have implemented nurse practitioners (NPs) to ensure access to high quality care in times of general practitioner (GP) shortages and changing health care needs of a multimorbid, ageing population. In Switzerland, NPs are currently being introduced, and their exact role is yet to be determined. The aim of this study was to get insight into patient characteristics and services provided in NP consultations compared to GP consultations in order to appraise whether the NP role meets the political and demographic demands in Swiss primary care.Methods This case study used retrospective observational data from electronic medical records of a family practice with one NP and two GPs. Data on patient-provider encounters were collected between August 2017 and December 2018. We used logistic regression to assess associations between the assignment of the patients to the NP or GP and patient characteristics and delivered services respectively. Results Data from 5,210 patients participating in 27,811 consultations were analyzed. The average patient age was 44.3 years (SD 22.6), 47.1% of the patients were female and 19.4% multimorbid. 1,613 (5.8%) consultations were with the NP, and 26,198 (94.2%) with the two GPs. Patients in NP consultations were more often aged 85+ (OR 3.43; 95%-CI 2.70-4.36), multimorbid (OR 1.37; 95%-CI 1.24-1.51; p <0.001) and polypharmaceutical (OR 1.28; 95%-CI 1.15-1.42; p <0.001) in comparison to GP consultations. In NP consultations, vital signs (OR 3.05; 95%-CI 2.72-3.42; p <0.001) and anthropometric data (OR 1.33; 95%-CI 1.09-1.63; p 0.005) were measured more frequently, and lab tests (OR 1.16; 95%-CI 1.04-1.30; p 0.008) were ordered more often compared to GP consultations, independent of patient characteristics. By contrast, medications (OR 0.35; 95%-CI 0.30-0.41; p <0.001) were prescribed or changed less frequently in NP consultations. Conclusions NPs could offer care to the growing number of multimorbid, polypharmaceutical elderly, and might relieve work pressure from the GPs. Hence, the NP role has the potential to meet the current political and demographic demands in Swiss primary care. An extended scope of practice, especially prescription rights, could foster further professional practice and role implementation.
Modeling the indoor tracking method based on particle water wave optimization
Authors: Guo Yangyong 
Published: February 2020

Abstract
A new tracking algorithm is proposed based on particle filter and water wave optimization for the problem that indoor tracking accuracy is not high enough. In this algorithm, the observation equation of the node location is first given using the least squares estimation algorithm based on the node signal intensity. Meanwhile, the algorithm steps of indoor tracking are designed using the water wave optimization, and the particle filter is introduced to accelerate the convergence. Finally, the performance of the algorithm is simulated through simulation experiments. The results show that the algorithm can adapt well to indoor environment.
MiR-133a-3p transferred by circulating microvesicles derived from myocardial ischemic preconditioning protects cardiomyocytes against hypoxia/reoxygenation injury
Authors: Zhao Junyu , Zhu Qian , Shang Man , Liu Miao , Wang Yilu , Li Yeyi , Wu Yanna , Liu Yanxia , Song Junqiu 
Published: February 2020

Abstract
Background Microvesicles (MVs) are submicron membrane vesicles as mediators of intercellular communication. The aim of our study was to investigate protective mechanism of circulating MVs derived from ischemic preconditioning (IPC-MVs) on myocardial I/R injury. Results Administration of IPC-MVs reduced infarct size and activity of lactate dehydrogenase (LDH) in myocardial I/R injury in vivo. Meanwhile, IPC-MVs could increase cell viability and reduce LDH activity in hypoxia/reoxygenation (H/R) injured H9c2 cells in vitro. Microarray analysis demonstrated that miR-133a-3p expression in IPC-MVs increased apparently compared with Sham-MVs. We found that miR-133a-3p increased cell viability, decreased LDH activity and apoptosis , as well as suppressed H/R-induced endoplasmic reticulum stress (ERS). MVs induced by hypoxic preconditioning enriched with FAM-miR-133a-3p allowed the transfer of miR-133a-3p to target cells. In addition, miR-133a-3p was significantly increased in H/R injured H9c2 cells by treatment with IPC-MVs. Epidermal growth factor receptor (EGFR) is a target gene of miR-133a-3p. AG1478 (EGFR inhibitor) significantly increased cell viability, decreased LDH activity and ERS-induced apoptosis in H9c2 cells under H/R injury. Conclusions The findings of this study showed that IPC-MVs exerted cardioprotective effects by transferring miR-133a-3p into H/R injured cardiomyocytes targeting EGFR, thus attenuating ERS-induced apoptosis. MiR-133a-3p transferred by IPC-MVs may provide a novel therapy for myocardial I/R injury.
Fire needle plus cupping for acute herpes zoster: Study protocol for a randomised controlled trial
Authors: Zhang Ying , Liang Zuohui , Li Shihua , Yang Ling , Guo Taipin , Yan Xu , Yang Juanjuan , Xu Qiannan , Zhang Qing , Zhao Jian , Li Cailian , Liu Xiuhong 
Published: February 2020

Abstract
Background Herpes zoster (HZ) is a common skin disease caused by invasion of the varicella-zoster virus into the ganglia and skin. Severe pain caused by HZ seriously affects the normal life of patients; thus, pain often becomes the patient’s first complaint. Fire needle plus cupping may be effective for acute herpes zoster (AHZ), but the evidence is insufficient. Methods This is a three-arm randomized controlled trial with an observation time of 1 week. A total of 96 patients with AHZ pain are divided into three groups by stratified randomization, with 32 in each group: (a) fire needle + cupping (FC); (b) famciclovir + gabapentin (FG), famciclovir hydrochloride, 3 × 0.25 g/d orally (p.o.), with an individualized dose of gabapentin 900-3600 mg/d p.o.; and (c) fire needle + cupping + famciclovir (FCF). The above intervention lasts for 1 week, and all patients receive analgesia (nonopioid analgesics [analgin or paracetamol] and opioid analgesics [tramadol or morphine]). Groups a and c undergo 1 to 7 sessions of fire needles and cupping treatments per patient, with gabapentin and analgesic medication administered depending on the patient’s needs. The primary outcome measure is the assessment of changes in pain intensity before and after treatment (visual analogue scale ranging from 0-100 mm). Secondary outcome measures are changes in substance P and beta-endorphin concentrations in peripheral plasma before and after treatment. Quantitative scoring methods are used to evaluate the symptoms and physical signs before and after treatment, including pain classification, local itching, burning sensation, fever, local lymphadenopathy, skin lesion area, blisters, herpes clusters, vesicular traits, ulcers, and pimples. In addition, analgesic needs and side effects are evaluated. Discussion: The results of this study will be obtained by randomised controlled trial(RCT), and the outcomes will be analyzed and evaluated to prove FC may be effective for AHZ. Trial registration :The registration number is ChiCTR1800015372. Registered on 28 March 2018.
The Impact of Fasting in Ramadan on Metabolic and Anthropometric Indices in Trained Type ΙΙ Diabetic Patients: A Prospective Observational Study
Authors: Yazdanyar Tayebe , Sohrab Mehrnoush , Ramezani Atena , Kashi Zahra , Abadi Parastoo Karimi Ali , Bahar Adele , Shirzad Mahboobeh , Abdolmaleki Elham Yousefi , Aarabi Mohsen 
Published: February 2020

Abstract
Background: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is, therefore, necessary for patients to receive proper education related to their physical activities, eating habits, blood glucose monitoring, and medications. The aim of this study was to investigate the effects of Ramadan fasting on metabolic and anthropometric indices in type ΙΙ diabetic patients.Methods: This prospective observational study was performed during Ramadan 2018. The study population consisted of diabetic patients who desired to fast and received information on physical activity, eating habits, blood glucose monitoring, and taking their medications before Ramadan. Fasting blood sugar (FBS), blood sugar 2-hour postprandial (BS2hpp), glycosylated hemoglobin (HbA1C), and the lipids profile were assessed before and after Ramadan month. FBS and BS2hpp were also evaluated on the fifteenth day of Ramadan. The significance level for data analysis was considered p<0.05.Results: Out of 40 diabetic cases who completed the study, 6 (15%) were male and 34 (75%) were female. The mean age of participants was 55.2 ± 9.3 years. The anthropometric variables, including weight, BMI, waist, and blood pressure, decreased significantly after Ramadan fasting (p<0.05). FBS decreased significantly (125.1 ± 27.4 vs 105.2 ± 21.4, p<0.0001) and serum triglyceride increased significantly (127.5 ± 45.5 vs 166.5±53.5 mg/dl, p<0.001) after fasting compared to pre-Ramadan measurement. Other variables remained unchanged.Conclusion: The results of this study indicate that type II diabetic patients who have controlled blood sugar and received information based on clinical guidelines about their lifestyle and medications can fast safely during the holy month of Ramadan.