bluuebunny/crossref_metadata_2025_split huggingface dataset:
A formação docente para atuação na educação infantil: uma análise das políticas públicas
Authors: Garcia Patricia Mara Almeida , Silva Paulo Sérgio Souza , Rodrigues Adriana 
Published: February 2025

As políticas públicas no Brasil, voltadas para a educação da primeira infância têm em todo seu percurso histórico colaborado para mudar a visão da Educação Infantil de assistencialismo, para uma concepção de infância centrada na integralidade do cuidar e do educar. Este trabalho propõe-se a debater acerca da Educação Infantil no âmbito das Políticas Públicas objetivando analisar os desafios e as possibilidades dentro do contexto brasileiro, fundamentado a partir de pesquisas descritivas bibliográficas da proposição legal da Educação Infantil no Brasil, suas propostas educacionais, bem como compreender a formação docente na relação entre o aporte teórico e legal da dessa modalidade com a prática docente. O estudo em si também fomenta de reflexões para uma Educação Infantil de qualidade, através das Políticas Públicas existentes, utilizando referenciais como: Base Nacional Comum Curricular (BNCC), Lei de Diretrizes e Bases da Educação Nacional (LDB, lei nº 9.294/ 96), a Resolução nº 5 de 17/12/2009 que fixa as Diretrizes Curriculares Nacionais para a Educação Infantil (DCNEI), e autores que abordam os desafios da criança na Educação Infantil, como: BERLINSKI, S.; CURY, C. R. J ; OLIVEIRA, R. R. A. e TEIXEIRA, B. de B., entre outros. As análises desenvolvidas neste trabalho visam subsidiar a discussão sobre a situação atual da educação infantil, como política pública, buscando-se a aproximação de objeto de estudo tão complexo, procura-se situar o lugar das políticas e dos programas atuais, de âmbito federal.
Community Empowerment Strategy in Tourism Village Development
Authors: Dionisius Jalung  , Sri Kamariyah  , Ika Devy Pramudiana  
Published: February 2025

This study aims to describe and analyze: Community Empowerment Strategies in Batu Majang, Long Bagun District, Mahakam Hulu Regency, East Kalimantan and Inhibiting and Supporting Factors Affecting Empowerment in Tourism Village Development. The research is qualitative descriptive analysis The data analysis technique uses a technique developed by McNabb (2002), namely Grouping the data according to key constructs, identifying bases for interpretation, developing generalizations from the data, testing alternative interpretations dan forming and/or refining generalizable theory from case study. The results of the study show that the Community Empowerment Strategy in the Development of Tourism Villages in Batu Majang which is carried out includes: Planning is carried out through community proposals which are then mapped to potential based on ususlan. Implementation of Community Empowerment in Tourism Village Development by involving all elements of Village Muspides, Tourism Awareness Groups and all communities, Providing guidance to the community in a sustainable manner by collaborating with the tourism office, increasing the productive economy. Evaluation or Monitoring of Community Empowerment in Tourism Village Development through a village-level musayawarah forum which is delivered in a village deliberative forum every 3 months. Factors that inhibit community empowerment in the development of Tourism Villages include limited resources, both budget and human resources, traditional community behavior, and limited land. The supporting factors encountered are the support of some people and the existence of promotional media that can support the existence of tourist villages.
The Influence of Work Stress and Organisational Culture on Production Employees Performance of PT Kayika Waskita Indonesia Jombang
Authors: Putri Ika Oktavia , Prasetyo Deni Widyo 
Published: February 2025

The aim of this research is to explore how work stress and organisational culture impact the job performance of production staff at PT Kayika Waskita Indonesia in Jombang. Data gathering involves the distribution of questionnaires, conducting interviews, observations, and documentation. This study utilizes quantitative methods with a descriptive approach to provide an overview of the research subject based on collected data or samples. The target population consists of production employees at PT Kayika Waskita Indonesia in Jombang. Probability sampling technique is employed to select a sample of 80 employees. Data analysis includes validity and reliability tests, classical assumption tests, multiple linear regression analysis, hypothesis testing using t tests, and determination of the coefficient of determination (R²) with the assistance of SPSS 21 software. The findings indicate that work stress negatively and significantly affects the performance of production employees at PT Kayika Waskita Indonesia in Jombang, whereas organisational culture has a positive and significant impact on their performance.
Melihat Persepsi Korupsi Masyarakat: Analisis Kolektivisme dan Gaya Pengambilan Keputusan
Authors: Saragih El Syafira , Mulya Yansa Alif 
Published: February 2025

Berdasarkan data dari Transparency Internasional for Indonesia (2023) dan Badan Pusat Statistik Indonesia (2024), menyatakan bahwa CPI atau Indeks Persepsi Korupsi negara Indonesia turun sebesar 0,07 poin dari 3,96 di 2023 menjadi 3,89 pada 2024. Praktik korupsi di Indonesia sendiri sudah mengakar, sistematis, kolektif dan berevolusi bentuk dan rupanya. Pada penelitian ini, peneliti berusaha untuk melihat persepsi korupsi masyarakat Indonesia pada saat ini dengan pengaruh budaya kolektif dan dimediasi oleh gaya pengambilan keputusan. Penelitian ini menggunakan pendekatan kuantitatif model mediasi (N = 120) dengan menyebarkan survei online. Analisis menggunakan tiga alat ukur berdasarkan CVS Scale dari Yoo (2016), GDMS oleh Baiocco, dkk (2009), dan CPS Scale dari Vieire, dkk (2022). Variabel kolektif (β = 0.204, F (1, 118) = 47.93, p = < 0.05), persepsi dan tipe pengambilan (β = 0.853, F (1, 118) = 85.15, p = < 0.05) dapat memprediksi satu sama lain. Gaya pengambilan keputusan (β = .137) mampu memediasi hubungan antara kolektif (β = .132) dengan persepsi korupsi. Berdasarkan analisa yang telah dilakukan, kolektif dan gaya pengambilan keputusan hanya mampu menjelaskan 45,9% dari persepsi tentang korupsi. Sehingga, masih banyak faktor yang mendorong praktik korupsi di Indonesia yang dapat dibahas pada penelitian selanjutnya.
Well-being Pada Narapidana : Sebuah Analisis Bibliometrik
Authors: Priyo Subagyo Panggih 
Published: February 2025

Artikel ini menggunakan analisis bibliometrik yang bertujuan untuk merangkum beberapa penelitian dengan tema well-being pada penderita Narapidana. Sumber data penelitian ini diperoleh dari Scopus periode tahun 2014—2024, diperoleh 1.279 dokumen kemudian dilakukan reduksi data sesuai dengan kategori yang telah ditetapkan, sehingga diperoleh 454 dokumen. Hasil penelitian menunjukan bahwa penelitian terkait well-being pada penderita Narapidana mengalami tren peningkatan tiap tahunnya, di mana tahun 2024 menjadi tahun dengan publikasi terbanyak. Fokus tren penelitian yang berhubungan dengan well-being pada Narapidana meliputi mental health, corecctional facility, social support, dan rehabilitation.
The effect of perioperative probiotics and synbiotics on postoperative infections in patients undergoing major liver surgery: a meta-analysis of randomized controlled trials
Authors: Wu Haopeng , Guan Zhihui , Zhang Kai , Zhou Lingmin , Cao Lanxin , Mou Xiongneng , Cui Wei , Tian Baoping , Zhang Gensheng 
Published: February 2025

Objective
To evaluate the effect of perioperative probiotics or synbiotics on the incidence of postoperative infections following major liver surgery.

Design
Meta-analysis

Data sources
PubMed, Embase, Scopus, and the Cochrane Library for relevant English-language studies published up to February 21st, 2024.

Eligibility criteria
Randomized controlled trials evaluating perioperative probiotics or synbiotics for preventing postoperative infections in patients undergoing major liver surgery.

Data extraction and synthesis
Outcomes included postoperative infection incidence, antibiotic therapy duration, length of stay in intensive care unit (ICU) and hospital. A random-effect model was adopted for the meta-analysis. The quality of included studies was evaluated using the Cochrane risk of bias tool.

Results
Ten studies involving 588 patients were included. Pooled analyses revealed that perioperative probiotics or synbiotics significantly reduced postoperative infection incidence (RR 0.36, 95% CI [0.24–0.54], P < 0.0001, I2 = 6%) and antibiotic therapy duration (MD −2.82, 95% CI [−3.13 to −2.51], P < 0.001, I2 = 0%). No significant differences were observed in length of stay in ICU (MD −0.25, 95% CI [−0.84–0.34], P = 0.41, I2 = 64%) or length of stay in hospital (MD −1.25, 95% CI [−2.74–0.25], P = 0.10, I2 = 56%).

Conclusions
This meta-analysis suggests that perioperative administration of probiotics or synbiotics may reduce the incidence of postoperative infections and duration of antibiotic therapy. Their use as adjunctive therapy during the perioperative period could be considered for patients undergoing major liver surgery.
Effects of Cocaine on the Placenta
Authors: Cejtin Helen E. , Young Stephanie A. , Ungaretti Joy , Anciaux Dominique , Imam Shaheen , Teopengco Ellen , Sander C. Maureen 
Published: July 2002

Adverse perinatal outcomes of gravidas using cocaine is well documented, but the effects on the placenta have been difficult to elucidate due to confounding factors such as concurrent use of other drugs. This study compares pathologic findings of 26 placentas from women who used only cocaine during pregnancy with findings from 26 controls. All women were from a similar socio-economic class and were controlled for gestational age and tobacco use. None of the cocaine placentas were from women whose toxicology screens were positive for drugs other than cocaine. In the 26 cocaine placentas, there was 1 infarct, 3 chronic villitis, and 1 segmental fibrosis, with none present in the controls. In the control group, there was 1 decidual vasculopathy and 1 thrombus in a maternal vessel, but none were in the cocaine placentas. Each group had 1 thrombus in a fetal vessel. The study group showed 6 cases of chorioamnionitis and 1 funisitis; the control group had 10 and 4 cases, respectively. None of the above or seven other features showed a statistically significant difference between the cases and controls. Cocaine is a potent vasoconstrictive agent that blocks re-uptake of norepinephrine at the adrenergic nerve terminals. Our study suggests that cocaine does not cause an increased incidence of any of the 15 clearly recognizable placental features examined.
Serotonin-related, anxiety/aggression-driven, stressor-precipitated depression. A psycho-biological hypothesis
Authors: van Praag HM 
Published: July 2002

SummaryThe concept of a 5-HT related, anxiety and/or aggression-driven, stressor-precipitated depression is formulated and discussed. It comprises the following elements. The 5-HT ergic disturbances found in some depressed individuals - and of them particularly lowered CSF 5-HIAA - are linked to the anxiety- and the aggression-components of the depressive sydrome. In this type of depression - called 5-HT related depression - dysregulation of anxiety and/or aggression are primordial and mood lowering is a derivative phenomenon. In other words this is a group of anxiety/aggression-driven depressions. The 5-HT ergic impairment in certain types of depression is a trait-phenomenon, ie, persists during remission. This disturbance makes the individual susceptable for perturbation of anxiety- and aggression-regulation. Anxiety and (overt or suppressed) anger, are core constituents of the stress-syndrome. Thus, the 5-HT ergic disturbance will induce a heightened sensitivity for stressful events, ie, the latter will induce more readily than normal, stress phenomena , among which anxiety and anger. The latter psychological features induce lowering of mood and thus “drive” the patient into a fullblown depression. Furthermore it is predicted that anxiolytics and serenics (ie, anti-aggressive drugs) that act via normalisation of 5-HT ergic circuits, will exert a antidepressant effect in 5-HT related depression,in additionto their therapeutic actions in anxiety disorders and states of increased aggressiveness, respectively. The exact nature of the 5-HT ergic impairment in 5-HT related depression has yet to be elucidated.
The implementation of reproductive health programs: experiences, achievements and challenges
Authors: Edouard L , Dodd N , Bernstein S 
Published: July 2002

AbstractAs a fundamental element of population strategies for international development, reproductive health has received much recognition since the International Conference on Population and Development held in Cairo in 1994. Nevertheless, much remains to be done to improve the understanding of the concept of reproductive health, support reproductive rights, operationalize reproductive healthcare within basic health services and promote a more conducive social, cultural and economic environment, especially for women and girls, to enable the attainment of reproductive health. Collaboration between governments and non‐governmental organizations will be crucial and obstetrician‐gynecologists have a unique role, through service provision, review of regulatory frameworks, education and advocacy, for the promotion of reproductive health.
In search of human dignity: gender equity, reproductive health and healthy aging
Authors: Diczfalusy Egon 
Published: July 2002

AbstractThis paper analyzes thenine pillars of human dignity(sufficient food, potable water, shelter, sanitation, health services, healthy environment, education, employment and personal security), which humankind tries to establish by followingnine approaches to reality(scientific, cultural, religious, ethical, economical, ecological, socio‐critical, philosophical and political) in a world drastically changed by nine revolutions (demographic, scientific, technological, communication, global identity, environmental, contraceptive, reproductive health and gender equity).The author's generation participate din these revolutions and contributed to the global intellectual process by which gender equity and reproductive health assumed a central role in world affairs. A rapidly aging world population constitutes another major challenge. Its likely impact on the very fundaments of our future social, economical, health and even political infrastructures is — as yet — incompletely comprehended by the international community.The International Federation of Gynecology and Obstetrics (FIGO) has and will continue to have and indispensable role in assisting humankind to reach its ultimate goal : human dignity.
Radical‐scavenging antioxidants in pre‐eclampsia and eclampsia
Authors: Shaarawy M , Aref A , Emad Salem M , Sheiba M 
Published: July 2002

AbstractObjective: Increased free‐radical activity may be implicated in the pathogenesis of pre‐eclampsia and knowledge of the response of the antioxidant systems is limited in pre‐eclampsia and lacking in eclampsia. Accordingly, this study was initiated to assess total antioxidant status in pre‐eclampsia and eclampsia. Method: Thirty‐five patients with pre‐eclampsia (20 mild and 15 severe), 10 patients with eclampsia and 20 normotensive women (controls) with singleton gestations in the third trimester participated in this study. Their freshly drawn blood was assayed for total antioxidant status colorimetrically using incubation mixture of ABTS, a peroxidase (metmyoglobin) and H2O2. In addition, serum fibronectin was determined by radial immunodiffusion. Result: Serum total antioxidant status levels in mild and severe pre‐eclampsia and eclampsia were significantly lower than that of healthy pregnant women (controls). The mean percent decreases amounted to 22%, 40% and 59%, respectively, indicating the propensity of these patients to oxidative stress. Conclusion: These results demonstrate that radical‐scavenging antioxidants are consumed by the increased free‐radical activity in pre‐eclampsia. The mechanisms by which free radicals are involved in endothelial dysfunction and renal injury are explained as evidenced by significant negative correlation of fibronectin and positive correlation of creatinine clearance with total antioxidants.
Depression in women suffering perinatal loss
Authors: Carrera L , Dı́ez‐Domingo J , Montañana V , Monleón Sancho J , Minguez J , Monleón J 
Published: July 2002

AbstractObjective: To analyze depression in women who have suffered perinatal loss in the present study.Methods: The level of depression was studied, by means of the Beck Depression Inventory (BDI), in two groups of women, mothers who suffered perinatal loss and received psychological intervention for 1 year and mothers with live‐birth babies. The BDI was recorded immediately after delivery and at 6 and 12 months postpartum. A third group of women with perinatal loss who received no intervention were studied only 12 months postpartum.Results: At the time of delivery, women who suffered perinatal loss showed higher levels of depression, as measured by higher scores on the BDI than women experiencing a live‐birth. At 6 months postpartum the intervention group showed improvement (lower BDI scores), but as a group they endorsed more depressive symptoms than the live‐birth group. At 12 months the perinatal loss group who received the 1‐year intervention was less depressed than the group who did not, and scored very similar to the live‐birth group.Conclusion: Women who experience perinatal loss endorse more depressive symptoms than mothers of live‐births, and these depressive symptoms can be ameliorated by a psychological intervention.
The management of high‐risk gestational trophoblastic tumours (GTT)
Authors: Newlands E.S. , Bower M. , Holden L. , Short D. , Brock C. , Rustin G.J.S. , Begent R.H.J. , Bagshawe K.D. 
Published: July 2002

AbstractBetween 1979 and 1995 we have treated 272 consecutive women with high‐risk (GTT including 121 previously treated patients who were treated with the weekly EMA/CO (etoposide, methotrexate, actinomycin D alternating with cyclophosphamide and vincristine). The median follow‐up is 4.5 years (range 1–16 years). The cumulative 5 year survival is 86.2% (95% confidence interval 81.9–90.5%). No deaths from GTT occurred later than 2 years after starting EMA/CO. In a multivariate analysis, adverse prognostic factors were the presence of liver metastases (p < 0.0001), interval from antecedent pregnancy > 24 months (p < 0.0001), brain metastases (p = 0.0008) and term delivery of antecedent pregnancy (p = 0.045). There were 11 (4%) early deaths while 213 (78%) achieved complete remission. 47 (17%) developed drug resistance to EMA/CO of whom 33 (70%) were salvaged by further cisplatinum based chemotherapy and sugery. 2 women developed acute myeloid leukaemia after treatment with EMA/CO. 56% of women who have been in remission for at least 2 years and had fertility conserving surgery have achieved pregnancy since completing EMA/CO and there have been 112 live births including 3 babies with congenital abnormalities.EMA/CO is an effective, easy to administer and well tolerated regimen for treating patient with high‐risk GTT. More than half of these women will retain their fertility.However, there is a small but significant increase in second malignancies.
The effect of information technology on learning in professional service organizations
Authors: Boone Tonya , Ganeshan Ram 
Published: July 2002

AbstractThis study examines the relationship between organizational experience and productivity in a professional service organization. The research addresses a gap in the existing literature with respect to organizational experience models in service organizations. Our findings confirm a significant, positive relationship between organizational experience and productivity. In addition, we investigate the effect of information technology on the relationship between organizational experience and productivity. The findings indicate that information technology which becomes a part of the production process is associated with productivity improvements, while information technology which merely documents or collects information is not.
LacZ andOMP are co‐expressed during ontogeny and regeneration in olfactory receptor neurons of omp promoter‐lacZ transgenic mice
Authors: Walters Eric , Grillo Mary , Oestreicher A. Beate , Margolis Frank L. 
Published: July 2002

AbstractThe ontogeny and cellular specificity of expression of β‐galactosidase activity and olfactory marker protein (OMP) are compared in olfactory tissue of the H‐OMP‐lacZ‐3 line of transgenic mice. In this line the expression oflacZ is driven by a 0.3 kb fragment of the rat OMP promoter. During fetal development,lacZ expression is detectable in olfactory receptor neurons (ORNs) shortly after the initial appearance of endogenous OMP. The β‐galactosidase marker was observed only in mature olfactory receptor neurons where it co‐localized with endogenous OMP. It was absent from immature neurons that express the growth associated phosphoprotein B50/GAP43. Lesion of the peripheral olfactory pathway by intranasal irrigation with Triton X‐100 eliminated expression of both OMP andIacZ in the olfactory neuroepithelium. Subsequent regeneration of the full complement of olfactory receptor neurons was associated with co‐expression of both OMP and β‐galactosidase activity. Neither OMP nor β‐galactosidase activity was induced in any other cell type of the regenerating olfactory mucosa. Thus, as little as 0.3 kb of the OMP promoter has the ability to targetlacZ expression to olfactory receptor neurons in a temporally and spatially defined manner. We discuss the potential utility of this transgenic line for future studies of the olfactory system.
Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas
Authors: Schinke Henrik , Heider Theresa , Herkommer Timm , Simon Florian , Blancke Soares Alexandra , Kranz Gisela , Samaga Daniel , Dajka Laura , Feuchtinger Annette , Walch Axel , Valeanu Laura , Walz Christoph , Kirchner Thomas , Canis Martin , Baumeister Philipp , Belka Claus , Maihöfer Cornelius , Marschner Sebastian , Pflugradt Ulrike , Ganswindt Ute , Hess Julia , Zitzelsberger Horst , Gires Olivier 
Published: December 2020

Head and neck squamous cell carcinomas (HNSCCs) have poor clinical outcome owing to therapy resistance and frequent recurrences that are among others attributable to tumor cells in partial epithelial‐to‐mesenchymal transition (pEMT). We compared side‐by‐side software‐based and visual quantification of immunohistochemistry (IHC) staining of epithelial marker EpCAM and EMT regulator Slug in n = 102 primary HNSCC to assess optimal analysis protocols. IHC scores incorporated expression levels and percentages of positive cells. Digital and visual evaluation of membrane‐associated EpCAM yielded correlating scorings, whereas visual evaluation of nuclear Slug resulted in significantly higher overall scores. Multivariable Cox proportional hazard analysis defined the median EpCAM expression levels resulting from visual quantification as an independent prognostic factor of overall survival. Slug expression levels resulting from digital quantification were an independent prognostic factor of recurrence‐free survival, locoregional recurrence‐free survival, and disease‐specific survival. Hence, we propose to use visual assessment for the membrane‐associated EpCAM protein, whereas nuclear protein Slug assessment was more accurate following digital measurement.