bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial intelligence techniques for Containment COVID-19 Pandemic: A Systematic Review
Authors: Alabool Hamzeh , Alarabiat Deemah , Abualigah Laith , Habib Mohammad , Khasawneh Ahmad M. , Alshinwan Mohammad , Shehab Mohammad 
Published: May 2020

Abstract
Due to the advantages offered by AI in containment the COVID-19 pandemic, the number of AI techniques has increased greatly. Although these techniques provide an acceptable start to COVID-19 pandemic control, they differ in terms of purpose, AI synthesis methods, datasets, validation approach. This increase and diversity in the numbers of proposed AI techniques can confuse decision makers and lead them to the dilemma of what is the appropriate technique under the specific conditions. Yet, studies that assess, analyze, and summarize the unresolved problems and shortcomings of current AI techniques for COVID-19 are limited. In the existing review studies, only individual parts of AI techniques, rarely the full solution, are reviewed and examined. Thus, this study aims to present a comprehensive systematic review on the application of AI techniques in containment the COVID-19 pandemic. The applied search strategy led to include 73 papers related to the Application of AI techniques for COVID-19 published from December 2019 to May 2020. Ten applications of AI for containment COVID-19 were identified. In addition, the analysis results of the systematic review revealed five deficiencies so that future research should take them into consideration.
Education in academic emergency medicine during the COVID-19 pandemic – our experience from an ongoing crisis
Authors: Mueller Matthias , Schriefl Christoph , Holzer Michael , Roeggla Martin , Laggner Anton N. , Ettl Florian 
Published: May 2020

Abstract
Background: The COVID-19 pandemic resulted in suspension of the whole teaching program at the Medical University of Vienna until the end of summer semester. Therefore, a substantial waste of learning time threatens. As the responsible department for emergency medicine teaching, we adapted our program to continue with our courses and maintain the learning progress. Our objective was to evaluate the number of conducted courses and to report the used methods.Methods: Teaching was classified in credit hours per week (CHW). One CHW represents 15 academic hours (45 minutes) during one semester. Computations were performed on basis of the official numbers from the prospectus of the university, or - if not available - were calculated with the formula above. Webinars were performed using CISCO Webex Events®, Webex Training® and ZOOM®. We further utilized Moodle® for resuscitation courses.Results: Overall, courses and clerkships equivalent to 80.2 out of 101.4 CHW (79.1%) will be held during the ongoing crisis in summer semester. Courses in winter semester were completed regularly. In the human medicine curriculum, we could perform 73.7 out of 94.9 CHW (77.7%). In the emergency lectures for the dentistry curriculum, we could adapt all courses to webinars (6.5 CHW, 100%). After adjustment for the exact number of students in each class, courses and clerkships equivalent to 78.7% could be conducted.Conclusions: Despite the challenge to be prepared for the treatment of numerous patients during an ongoing pandemic, we could maintain the majority of our teaching responsibilities. Although sufficient skill training cannot be achieved under those circumstances, we could provide the theoretical backgrounds to allow students further continuation in their studies.
STUDY OF TIME FREQUENCY TRANSFORMS APPLIED TO POWER QUALITY SIGNALS
Authors: Almeida Richard Bini , Watanabe Kenji , Victer Silvia Mara da Costa Campos 
Published: May 2020

This work presents a scientific study on Short-Time Frequency Transforms (STFT) with different windows, also called Windowed Fourier Transforms, applied to power quality signals. Additionally, it deals with S transforms, with its frequency-dependent window. The disturbances related to energy quality have non-stationary nature, in which the spectral content varies over time. So, the Fourier Transform is not appropriate for such analysis, because it doesn’t show time locations, only information about existing frequencies in the signal. Therefore, the spectral analysis by windowed transforms helps to identify and detect a series of defects associated to these power signals. The motivation behind this document is to verify which window will provide a more precise identification of the characteristics of the disturbances in time-frequency domain. For this work, synthetic signals were generated for some of these disturbances, and their spectra were compared considering Gaussian, Hann and Blackman windows, as well as the S transform. Based on the obtained results, it was verified that each transform presents different behaviours acording to the input signal, except for the ones with Hann and Blackman windows, that showed similar spectra. For all of them, there is always a tradeoff between time and frequency resolutions. Therefore, the choice of the window must be done according to the desired outputs. The Dev-C ++ ® IDE was used for C ++ programming, and the Gnuplot ® program for graphics generation.
PERFORMANCE EVALUATION OF ENERGY RECONSTRUCTION METHODS IN HIGH ENERGY PHYSICS EXPERIMENTS
Authors: Marin Juan Lieber , Furtado de Simas Filho Eduardo , Sotto-Maior Peralva Bernardo , Inácio Gonçalves Guilherme , Manhães de Andrade Filho Luciano , Manoel de Seixas José 
Published: May 2020

The discovery of particles that shape our universe pushes the scientific community to increasingly build sophisticated equipment. Particle accelerators are one of these complex machines that put known particle beams on a collision course at speeds close to that of light. When collisions occur, subproducts are produced and measured by the calorimeter system, which entirely absorbs these subproducts. Typically, a high-energy calorimeter is highly segmented, comprising thousands of dedicated readout channels. The present work evaluates the performance of two energy reconstruction algorithms: the OF (Optimal Filter) and MAE (Multi-Amplitude Estimator), which was recently proposed to deal with the signal superposition (pile-up). In order to evaluate the energy estimation efficiency, artificial data were used, considering several pile-up levels. The statistics from the energy estimation is employed to compare the performance achieved by each method. A second analysis is made to quantify the MAE sensitivity to the pedestal parameter. The results show that the MAE method presents a better performance than the OF method and the usage of an uncalibrated pedestal value compromises the MAE performance.
Numerical simulation model of vertical velocity distribution in a channel with artificial floating bed
Authors: Bai Yu , Duan Yonggang , Yue Wenjun 
Published: May 2020

Abstract
Artificial floating bed (AFB), as a novel type of ecological drainage ditch, is extensively used worldwide. To more effectively design the structure of the project, an accurate velocity model is required. In this study, a two-dimensional Lattice Boltzmann method (LBM) was employed for the simulation of the vertical velocity in a channel with AFB. The large eddy simulation (LES) was conducted to simulate turbulent flows, while the drag force of AFB was discretized with a centered scheme. Two sets of experimental data were used to verify the model, the mean value of root mean square error (RMSE) and coefficient of determination (R2) are 0.93 and 1.84, respectively. This proved that the proposed model is more effective to simulate the vertical velocity in a channel with AFB.
Exploration of the Two-Way Adjustment Mechanism of Rhei Radix et Rhizoma for Cardiovascular Diseases
Authors: Pei Lishan , Shen Xia , Qu Kai , Tan Conge , Zou Junbo , Wang Yanxia , Ping Fan 
Published: May 2020

Aim and Objective:
Myocardial infarction, cerebral infarction, and other diseases
caused by vascular obstruction have always jeopardized human life and health. Several reports
indicate that Rhei Radix et Rhizoma has a good clinical effect in the prevention and treatment of
cardiovascular diseases. Owing to the complexity of herbal medicine, the pharmacodynamic
mechanism of Rhei Radix et Rhizoma is still unclear. The objectives of this study were to explore
the two-way adjustment mechanism of Rhei Radix et Rhizoma and provide a new solution for the
prevention and treatment of cardiovascular disease.

Materials and Methods:
This study used data mining, reverse pharmacophore matching, network
construction, GO and KEGG Analysis, and molecular docking to investigate the two-way
adjustment mechanism of Rhei Radix et Rhizoma. The methods used were based on systems
pharmacology and big data analysis technology.

Results:
The results suggest that Rhei Radix et Rhizoma uses a two-way adjustment of activating
blood circulation, as well as blood coagulation in the prevention and treatment of cardiovascular
diseases. The components involved in activating blood circulation are mainly anthraquinone
components. The corresponding targets are NOS2, NOS3, CALM1, and the corresponding
pathways are calcium signaling pathway, VEGF signaling pathway, platelet activation, and the
PI3K-Akt signaling pathway. For blood coagulation, the components are mainly tannin
components; the corresponding targets are F2, F10, ELANE, and the corresponding pathways are
the neuroactive ligand-receptor interaction, complement and coagulation cascades.

Conclusion:
This study indicated that Rhei Radix et Rhizoma exerts the two-way adjustment of
activating blood circulation and blood coagulation in the prevention and treatment of
cardiovascular diseases. It can make up for the side effects of the existing blood circulation drugs
for cardiovascular disease, only activating blood circulation, and the uncontrollable large-area
bleeding due to the long-term use of the drugs. This study provides a material basis for the
development of new blood-activating drugs based on natural medicine.
Flaxseed for Health and Disease: Review of Clinical Trials
Authors: Shayan Mersedeh , Kamalian Safa , Sahebkar Amirhossein , Tayarani-Najaran Zahra 
Published: May 2020

Background:
Flaxseed (Linum usitatissimum) is an oil-based seed that contains high
amounts of alpha-linolenic acid, linoleic acid, lignans, fiber and many other bioactive components
which is suggested for a healthier life. Nowadays, flaxseed is known as a remarkable functional
food with different health benefits for humans and protects against cardiovascular disease,
diabetes, dyslipidemia, obesity and altogether metabolic syndrome.

Methods:
To review the bioactive components of flaxseed and their potential health effects,
PubMed and Scopus were searched from commencement to July 2019. Keywords including:
"flaxseed", "Linum usitatissimum", "metabolic syndrome", "obesity", "inflammation", "insulin
resistance", "diabetes", "hyperlipidemia" and "menopause" were searched in the databases with
varying combinations.

Conclusions:
Consumption of flaxseed in different forms has valuable effects and protects against
cardiovascular disease, hypertension, diabetes, dyslipidemia, inflammation and some other
complications. Flaxseed can serve as a promising candidate for the management of metabolic
syndrome to control blood lipid levels, fasting blood sugar, insulin resistance, body weight, waist
circumference, body mass and blood pressure.
Preparation of A Magnetic Nanosensor Based on Cobalt Ferrite Nanoparticles for The Electrochemical Determination of Methyldopa in The Presence of Uric Acid
Authors: Najafi Khadijeh , Asadpour-Zeynali Karim , Mollarasouli Fariba 
Published: May 2020

Aim and Objective:
Methyldopa is one of the medications that is used for the treatment
of hypertension. Therefore, the determination of methyldopa in the presence of other biological
components is essential. In this work, a promising electrochemical sensor based on CoFe2O4
magnetic nanoparticles modified glassy carbon electrode (CoFe2O4/GCE) was developed for
electrochemical determination of methyldopa in the presence of uric acid. Cobalt ferrite
nanoparticles were synthesized via chemical method.

Materials and Methods:
Characterizing the CoFe2O4 was investigated by field emission scanning
electron microscopy (FESEM), X-ray diffraction (XRD), energy dispersive X-ray spectroscopy
(EDX), transmission electron microscope (TEM), and cyclic voltammetry techniques.

Results:
Under the optimal experimental conditions, the current response of the electrochemical
sensor obtained with differential pulse voltammetry was increased linearly in the concentration
range from 1.45 to 15.1 μmol L−1 with the detection limit of 1.07 μmol L−1 for methyldopa. Also,
by using the proposed method, methyldopa and uric acid could be analyzed in a mixture
independently. The difference in peak potential for analytes is about 150 mV.

Conclusion:
The present sensor was successfully applied for the determination of methyldopa in
the presence of uric acid in biological samples and the pharmaceutical samples with satisfactory
results.
Risk Factors of Preeclampsia among Pregnant Women in Khorramabad (West of Iran)
Authors: Mardani Mahnaz , Teymouri Farshad , Rezapour Maryam 
Published: May 2020

Background:
Preeclampsia occurs in 2-10% of pregnancies, worldwide, and is characterized
as a combination of hypertension and proteinuria.

Objective:
The purpose of this study is to determine the risk factors associated with the incidence of
preeclampsia in the west of Iran and associated factors.

Methods:
This is a cross sectional study that was performed on 740 pregnant women between 2014-
2017, who were referred to different health care centers of Khorramabad. The data was collected
from these centers and a questionnaire was filled for every woman that included age, height, gender
of the neonate, number of pregnancies, multiparity, season of the pregnancy, birth weight, mothers’
body mass index (BMI) before delivery, smoking history and diagnosis of preeclampsia. The data
obtained was statistically analyzed using SPSS software.

Results:
Of the 760 subjects included, 1.1% (8 cases) were reported to be presented with
preeclampsia. We found a significant difference between non pre-eclamptic and pre-eclamptic patients
in terms of BMI (p=0.006), number of pregnancies (p<0.05), maternal age (p<0.05) and
weight (p=0.004). With an increase in BMI and the number of pregnancies, the risk of preeclampsia
was elevated. Pre-eclamptic mothers had higher body weight than non-pre-eclamptic ones (75.9 kg
vs. 65.6 kg) and the prevalence of preeclampsia increased with age.

Conclusion:
The prevalence of preeclampsia was seen to be positively associated with higher BMI,
pregnancy rate, mother weight and age are associated with higher prevalence of preeclampsia.
COST-EFFECTIVE ANALYSIS IN TREATING DIABETES MELLITUS WITH COMORBIDITY
Authors: JAFARNIA MINA , DR DEEPIKA , RAVESHI FARZANEH , KIRUBAKARN J JOHN 
Published: May 2020

Objective: The main objective of this study is to sort out the most common prescription patterns and their cost-effective analysis (CEA).
Methods: A prospective study design is followed to collect the data. Based on the percentage, the first three comorbidities which occupy a major part of the sample are taken into consideration. The top two used prescriptions for each comorbidity are selected and CEA is performed for those.
Results: Diabetes mellitus (DM) with hypertension (HTN) comprise the majority of the sample (37%). Two majorly used prescription patterns are sorted out and CEA is performed which revealed that prescription pattern A is more cost effective than prescription pattern B. Second major part of the sample is occupied by only cases with DM (21%) which is excluded as it does not have any commodities. After only DM, DM + infections occupy a major part (8%). Two majorly used prescription patterns are sorted out and CEA is performed which revealed that prescription pattern A is more therapeutically effective than prescription pattern B but not cost effective. The 3rd major comorbidity is DM + CVA (8%). In this case, the results demonstrated that prescription pattern A is more cost effective than prescription pattern B.
Conclusion: The major commodities of DM are HTN, infections, and coronary artery disease. The cost-effectiveness evaluation revealed that physicians are only considering the therapeutic efficacy as a major concern but not the economic burden. This study concludes the importance of considering the financial burden with relationship to their respective therapeutic efficacy provided by an individual prescription.
THE IMPACT OF MEETING ACCREDITATION STANDARDS ON THE QUALITY OF THE ELECTRONIC HEALTH RECORDS
Authors: HOSSAM ATTIA MOHAMED , IBRAHIM ABDELNASSER 
Published: May 2020

Objective: Electronic health records (EHRs) are considered a way to make the management of patient information easier, improve efficiency, and decrease costs related to medical information management. Compliance with requirements from accreditation bodies on quality of documentation ensures the complete and accurate patient information in the EHR. The purpose of this study is to measure the effect of quality accreditation on the quality of documentation in the EHR.
Methods: A simple random sample of 18% of patient records was manually selected each month during the entire study period from the population of discharged patients. The auditing process included 18 months starting from January 2014 until June 2015. The data collection was performed by a quality management unit using a modified medical record completeness checklist adapted from Joint Commission International (JCI) criteria.
Results: The results of the study show the improvement in compliance with complete medical records’ documentation after the JCI accreditation. However, after the accreditation, the compliance suffers a dramatic fall which could be referred to the post-accreditation slump. The compliance then improved again to reach higher levels of compliance. Using paired t-test, the mean of total compliance with complete and accurate medical records in October 2014 was less than in May 2015.
Conclusion: This study highlighted the performance of one process before and after the first accreditation of the organization showing the real difference between the performance before and after the accreditation and explaining the drop that happened just after the accreditation.
ANALYSIS OF CO-OCCURRENCE OF AUTISM SPECTRUM DISORDER WITH OTHER NEUROLOGICAL DISORDERS
Authors: CHANDRAKALA ELUMALAI , NAGARAJ KAKANAHALLI 
Published: May 2020

Objective: The present study explores the co-occurrence of autism spectrum disorder (ASD) with associated disorders such as epilepsy, attention deficit hyperactive disorder (ADHD), Down’s syndrome (DS), and cerebral palsy (CP).
Methods: This cross-sectional study was carried out in special schools of four districts in Karnataka. A total of 49 ASD individuals were identified among 552 developmentally challenged children. ASD individuals were screened for associated neurological disorders and segregated the data as ASD, ASD with epilepsy, ASD-epilepsy-ADHD, ASD with DS, and ASD with CP. The karyotype analysis was carried out for chromosomal anomalies.
Results: It is found that 57% of the individuals showed only ASD features and the remaining 43% shared ASD features with other neurological disorders. Among 43% of comorbidity, 35% of ASD individuals have epilepsy, 2% have epilepsy-ADHD, 4% have DS, and 2% have CP.
Conclusion: This study supports the strong association between ASD with epilepsy, DS, ADHD, and CP. However, the extent of association of ASD with epilepsy is higher than other neurological disorders. As both are complex neurological disorders, they both show intellectual disability and involve multiple genetic factors. The present investigation is the unique and first report of this study region and also supports earlier studies, suggesting that there is an association of ASD with other neurological disorders.
EVALUATION OF THE ANTICANCER PROPERTIES OF TURMESAC® IN HUMAN CERVICAL ADENOCARCINOMA
Authors: HM FIROZ , S NANJUNDAIAH , CT SADASHIVA 
Published: May 2020

Objective: In the current study, an extract of turmeric rhizome (Turmesac®) was evaluated for possible anticancer activity in human cervical adenocarcinoma (HeLa) cells.
Methods: Turmesac®’s ability to elicit cytotoxicity in cancer cells was evaluated by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay (MTT) assay, where the IC50 value was determined. Apoptosis induction and cell cycle arrest were analyzed by flow cytometry post-Turmesac® IC50 value treatment for 24 h.
Results: The determined IC50 value of Turmesac® in HeLa cells was 115.12 μg/ml. This concentration was able to induce apoptosis 2 times greater than the apoptotic standard, camptothecin, treated cells. Cell cycle arrest was observed at the G0/G1 and S phases in Turmesac® treated HeLa cells.
Conclusion: Turmesac® shows the potential of being a promising anticancer agent that may be incorporated into chemotherapies, but further study is required to elucidate the exact mechanisms involved with longer treatment duration, as would be the case in clinical trial phases.
COMPARISON OF PERFORMANCE OF TWO WIDAL TEST TECHNIQUES WITH STOOL CULTURE IN THE DIAGNOSIS OF TYPHOID FEVER AT THE DSCHANG DISTRICT HOSPITAL, WEST CAMEROON
Authors: NATHEU CERGE KAMHOUA , PHÉLIX TELEFO BRUNO 
Published: May 2020

Objective: This study is aimed to compare the performance of two Widal test techniques with stool culture in the diagnosis of typhoid fever.
Methods: A cross-sectional study was performed at the Dschang District Hospital in patients clinically suspected to have typhoid fever, whose stool was collected for stool culture. Furthermore, venous blood was collected and the serum was tested by both Widal slide agglutination test and Widal tube titration test.
Results: The results showed that out of 750 participants include in the study, 325 (43.33%) were positive for Widal slide agglutination test, 174 (23.20%) for Widal tube titration test, and 159 (21.20%) for stool culture. The sensitivity, specificity, positive predictive value, and negative predictive value of Widal slide agglutination test with respect to stool culture were 97.48%, 71.23%, 47.69%, and 99.22%, respectively, but 100%, 97.46%, 91.37%, and 100% for the Widal tube titration test. With the stool culture, Widal slide agglutination test had a moderate agreement (kappa = 0.47), but Widal tube titration test had an absolute agreement (kappa = 0.94).
Conclusion: Widal tube titration test should be used in place of Widal slide agglutination test in the diagnosis of typhoid fever in the case of limited access to stool culture test.