bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual Orientation, Femininity, and Attitudes Toward Menstruation Among Women: Implications for Menopause
Authors: Matsick Jes , Kruk Mary , Wardecker Britney 
Published: December 2020

Abstract
Women differ in how they psychologically respond to the end of menstruation and onset of menopause (Lorber & Moore, 2002); however, little empirical evidence exists for understanding how sexual orientation and gendered dynamics contribute to menopausal experiences. Do women’s attitudes toward the cessation of menstruation vary by sexual orientation? Using data from the Midlife in the U.S. Study (MIDUS, Wave 2; N=2,951), we test how sexual orientation relates to attitudes toward menstruation cessation through norms and values surrounding womanhood (i.e., “traditional femininity concerns,” such as worries about fertility and attractiveness). Cisgender heterosexual women, compared to sexual minority women, expressed greater regret of menstrual periods ending, and heterosexual women’s heightened concerns about traditional femininity mediated the association between sexual orientation and regret, b=-.09, 95%CI [-.176,-.008]. This research yields implications for understanding aging stigma and women’s health, and we discuss how menopause may be differently experienced by women based on sexual orientation.
Coping With Hurricane Matthew: Lessons Learned on the Importance of Relationships
Authors: Gibson Allison , Engelhardt Ethan , Murphy Erin 
Published: December 2020

Abstract
The effects of natural disasters are daunting among older populations, especially those with intersecting vulnerable social locations, such as low-income aging racial/ethnic minorities. Yet, there is a paucity of literature on these experiences. The purpose of this study was to explore the experiences of this population before and during the 2016’s Hurricane Matthew. Using a modified grounded theory approach, study participants were recruited through a snowball method and through flyers that were posted throughout affected communities. Semi-structured interviews were used in this study. The analysis focused on the identification of themes. The study aimed to gain knowledge of the experiences of 15 aging minorities with Hurricane Matthew (n=15). The sample was primarily 73.3% females, with a mean age of 69, and of racial/ethnic minorities (53.3% Black and 46.7% Hispanic). All participants self-identified as low-income. The main theme that emerged from this study on how low-income aging minorities cope with natural disasters was the reliance on social capital and the importance of human relationships. The results suggest that in the context of having low-income, aging minority rely on a range of support. Some support came through information and tangible help they received from family, friends, church community, and neighbors. Bridging social capital came from federal and non-profit agencies as well as help received from their employers. Pre-disaster planning should focus on supporting older populations in building social capital. This may be especially beneficial for low-income, aging minority, who may lack adequate financial resources on which to rely.
Clark Tibbitts Award Lecture
Authors: Hancock Cynthia 
Published: December 2020

Abstract
The Clark Tibbitts Award lecture will feature an address by the 2020 award recipient, Jan Abusharkrah, PhD, FAGHE. AGHE’s Clark Tibbitts Award was established in 1980 and named for an architect of the field of gerontological education. The award is given each year to an individual or organization that has made an outstanding contribution to the advancement of gerontology and geriatrics education.
Development and Validation of a Community Assessment Tool for Diverse Rural Family Caregivers
Authors: McCarthy Michael , Hustead Morgan Lee-Regalado , Bacon Rachel , Garcia Yolanda Evie , Dunn Dorothy , Williamson Heather , Baldwin Julie 
Published: December 2020

Abstract
The aging of the United States population has led to an increase in the prevalence of Alzheimer’s Disease and Related Dementias (ADRD). Many individuals with ADRD receive care from family members and friends who, themselves, experience poor health outcomes. ADRD family caregivers from diverse backgrounds are frequently underserved by health and social service systems. However, research suggests that diverse caregivers possess culturally-based strengths that serve as protective factors against poor outcomes. This presentation reports findings from a study to develop and validate a community assessment of the needs, assets, and resources of rural Latinx and Native American ADRD family caregivers. Initial assessment items were based upon validated measures developed for diverse ADRD and comparable caregiver populations. A Delphi process was used to obtain ratings from a 9-member expert panel (ADRD policy makers, providers, and family caregivers) about the degree to which the assessment was: (1) inclusive of different cultural groups; (2) respectful of cultural values and norms; (3) comprehensive with respect to needs, assets, and resources, and; (4) relevant to the lived experiences of diverse rural caregivers. Experts also provided qualitative feedback about modifying phrases to make the assessment more relevant to diverse respondents, removing sections, and adding items and response options to better reflect rural life. After two formal rounds of review and multiple iterations, between 77% and 100% of experts agreed that all sections of the assessment met criteria. Findings highlight the benefits of a systematic process for developing and validating community assessments for diverse, rural populations.
Aging, Senescent Cells, and Senolytic Drugs: The Path to Translation
Authors: Kirkland James 
Published: December 2020

Abstract
Senescent cells (SC) accumulate with aging and at causal sites of multiple chronic disorders and diseases, including those accounting for the bulk of morbidity, mortality, and health expenditures. SC do not replicate. Some SC release factors that cause tissue dysfunction, the senescence-associated secretory phenotype (SASP). Transplanting small numbers of SC into younger mice to above a critical threshold leads to frailty, early onset of multiple age-related diseases, and premature death. A report in 2004 showing caloric restriction causes both healthspan extension and delayed SC accumulation prompted us to begin efforts to discover senolytic drugs, agents that selectively eliminate SC. We used a hypothesis-driven, mechanism-based strategy to discover senolytics, reasoning that senescent cell anti-apoptotic pathways (SCAPs) exist that defend SC against their own SASP, allowing them to survive, despite killing neighboring cells. Senolytics cause SC apoptosis by transiently disabling these SCAPs. Because SC take weeks to re-accumulate, senolytics can be administered intermittently – a “hit-and-run” approach. Senolytics delay, prevent, or alleviate frailty and cardiovascular, neuropsychiatric, liver, kidney, musculoskeletal, lung, eye, hematological, metabolic, and skin disorders as well as complications of organ transplantation, radiation, and cancer treatment in pre-clinical models. As anticipated for agents targeting the fundamental aging mechanisms that are “root cause” contributors to multiple disorders, potential uses of senolytics are protean, potentially alleviating over 40 conditions in preclinical studies, opening a new route for treating age-related dysfunction and diseases. We review the discovery of senolytics and potential strategies for translation into the clinic. Early trials indicate effectiveness of senolytics in humans.
Margret M. and Paul B. Baltes Award
Authors: Silverstein Merril 
Published: December 2020

Abstract
The lecture will be given by the2019 Baltes Award recipient, Allison Bielak, PhD, FGSA, of Colorado State University. The recipient of the2020 Baltes Award is William J. Chopik, PhD. The Margret M. and Paul B. Baltes Foundation Award in Behavioral and Social Gerontology recognizes outstanding early-career contributions in behavioral and social gerontology. The award is generously funded by the Margret M. and Paul B. Baltes Foundation.
Multidisciplinary Healthcare Providers’ Perspectives on Managing Suspected Elder Abuse in the Healthcare Setting
Authors: Makaroun Lena , Klima Gloria , Nichols Michele , Rodriguez Keri , O’Hare Ann , Rosland Ann-Marie 
Published: December 2020

Abstract
Elder abuse (EA) is common and has devastating health consequences, yet is rarely detected by healthcare professionals. Veterans are at high risk for EA, and the VA has unique resources (e.g., comprehensive social work services) that can help address EA in the healthcare setting. This qualitative study aimed to assess perceived barriers and facilitators to detecting, reporting, intervening on and monitoring EA for VA providers. Providers from two VA facilities were recruited to participate in a one-on-one semi-structured interview. Transcripts of audio-recorded interviews were analyzed using thematic content analysis. Participants (n=22) were 82% female, age 33-64 years, had 4-25 years practicing in VA, and varied in discipline (e.g., nurse, physician, social worker) and practice setting (e.g., emergency department, geriatrics, primary care). For detecting EA, patient and caregiver cognitive impairment were frequently cited barriers, while an interdisciplinary team approach and ability to do home visits were noted facilitators. Common challenges with reporting EA to adult protective services (APS) were perceived lack of APS follow up and discrepancies in VA provider and APS investigator findings. While removing a patient from an unsafe living situation was a frequently cited successful intervention, providers also expressed feeling conflicted when infringing on patient autonomy. Poor communication with APS, patient loss to follow up, and caregiver interference made monitoring EA cases more difficult; intensive case management and in-home services facilitated monitoring. In conclusion, healthcare professionals see interdisciplinary care, in-home care, and better coordination with APS as key facilitators to managing suspected EA in the healthcare setting.
Intersectional Discrimination Attributions and Health Outcome among American Older Adults
Authors: Lu Peiyi , Kong Dexia , Shelley Mack , Davitt Joan 
Published: December 2020

Abstract
Discrimination has been consistently documented to relate to adverse health outcomes. However, most existing research focused on a single discrimination attribution (e.g. ageism). Few studies considered multifaceted discrimination attributions. Guided by an intersectionality framework, this study examined intersectional discrimination attributions and their associations with health outcomes. Older respondents (aged &gt;50) from the Health and Retirement Study in 2014-2015 were included in the analysis (n=6,286). Their experiences and self-perceived reasons (age, gender, sexual orientation, race, national origin, religion, financial status, weight, physical appearance, disability, and others) for everyday discrimination were examined. Latent class analysis was employed to ascertain the profiles of subgroups characterized by their intersectional discrimination attributions. Regression models examined the correlates of the class memberships and the associations with health outcomes. Six classes were identified: class 1 (54.52% of the sample) had no/minimal discrimination experience; Class 2 (21.89%) experienced primarily ageism; class 3 (8.81%) reported discrimination based on age/gender/national origin/race; class 4 (7.99%) attributed discrimination to financial/other reasons; class 5 (5.87%) experienced discrimination based on age/weight/physical appearance/disability; and class 6 (0.92%) perceived discrimination from almost every aspect. Intersectional discrimination attributions were associated with poorer self-rated health, and greater levels of depressive symptoms and loneliness. The associations between intersectional discrimination and cognition were not statistically significant. This study found multiple marginalized identities co-occur and compound to contribute to perceived everyday discrimination among American older adults. Those experiencing discrimination due to multiple reasons warrant particular attention. Results underscore the utility of an intersectional approach in understanding discrimination in later life.
Out-of-Pocket Expenses Related to Aging in Place for Older People Experiencing Frailty: A Scoping Review
Authors: Moody Elaine , Ganann Rebecca , Macdonald Marilyn , Weeks Lori , Orr Liz , Jefferies Keisha , Ploeg Jenny , Misener Ruth Martin 
Published: December 2020

Abstract
Supporting older people to live in the community as they experience health and functional changes has become a priority for policy makers, health system leaders and community members, including many older people themselves. Aging-in-place has been promoted as a way to support the sustainability of health care systems and limit health care and societal costs. However, the expenses borne by individuals and caregivers to support older people to age-in-place when experiencing changes in health and functional ability are often not considered in health care literature and policy. We conducted a scoping review using Joanna Briggs Institute methodology to explore the out-of-pocket expenses for people with frailty living in the community. We included research and policy papers on community-dwelling people over 60 and experiencing frailty. Findings about financial out-of-pocket expenses were extracted. A total of 9669 sources were screened by two reviewers and 42 sources were included. The sources were from 17 countries, most from the US, and had various designs, including 14 qualitative designs, 15 cross sectional, 11 other quantitative and 2 policy discussions. The sources most often reported expenses related to home care (16), medication (12), housekeeping (10), transportation (8), and medical equipment (6). Gaps in the body of literature include lack of a consistent measure of out-of-pocket expenses and cost considerations of co-housing programs. The context—including policy, community and personal—was particularly important to the experience of out-of-pocket expenses for people with frailty, and further research is needed to expand on this knowledge.
Aging Across the Life Course: Research Collections Available From the National Archive of Computerized Data on Aging
Authors: McNally James 
Published: December 2020

Abstract
The creation and maintenance of sustainable data archives can be challenging, but it offers clear advantages. Properly curated data can be used by multiple researchers, testing a variety of hypotheses, and increasing the return on investment to the expensive process of data collection. Having an internally managed archival system also provides greater control and autonomy in the equitable distribution of data resources. This process ensures all researchers will have full use of the data for original research, teaching, and new directions once the data leaves the control of the local investigator’s control. This poster reviews the advantages of having a local strategy geared toward the preservation and sharing of gerontological research data. Using the National Archive of Computerized Data on Aging (NACDA) as a working example, the poster offers an overview of collections at NACDA. Using our metadata tools and variable search database, NACDA can identify studies in its collections that examine aspects of aging and health among adults during their lifecourse. Many of the studies are longitudinal or repeat measure cross-sectional studies. We are also able to identify studies that focus on aging that are not maintained by NACDA but which are available to interested researchers. This poster focuses on newly released work by NACDA that has compared to major aging studies (NHATS and NSHAP) and organized them into quasi-harmonized files for download and analysis by the gerontological research community. These recently available enhancements will allow researchers to obtain user-friendly comparative data for these complex studies.
Change in Body Mass Index is Associated with Change in Cognition in Older Adults
Authors: Douglas Joy , Crowe-White Kristi , Ellis Amy , Bui Chuong , Voruganti Saroja , Yaffe Kristine 
Published: December 2020

Abstract
Background: Alzheimer’s disease and related dementias affect one in ten Americans age 65y and older. Considering the rapid growth of the aging population, identifying modifiable risk factors for cognitive decline is a public health priority. Although weight change later in life is common, its impact on cognition is unclear. The objective of this study was to examine the relationship between change in body mass index (BMI) and cognition among older adults. Methods: The Health, Aging, and Body Composition Study was a prospective study of community-dwelling adults ages 70-79y at baseline (n=3,075; 49% males, 42% African-American). Using baseline and year 10 visit data, we evaluated change in BMI and change in cognition measured by the Modified Mini-Mental Status Exam (3MS) using a linear mixed model. Change in 3MS scores were regressed on changes in time-varying BMI after controlling for blood pressure, glucose, cholesterol, race, education, biological sex, and APOE genotype. Results: At baseline, average BMI was 27.4 (n=3075) and average 3MS was 90.1 (n=3061). At year 10, average BMI was 27.1 (n=1600) and average 3MS was 88.6 (n=1598). Higher BMI was associated with less cognitive decline (ceteris paribus). This finding suggests that weight gain is associated with cognitive maintenance. The effect of an increase in BMI was largest for those underweight at baseline. Conclusion: Among underweight older adults, an increase in BMI may be desirable for maintaining cognition. Although more research is needed, these findings suggest the need for interventions to prevent unintentional weight loss among older adults.
Influences of Dementia on Long-Term Surgical Outcomes in Older Adults After Hip Fracture
Authors: Xue Tingzhong (Michelle) , McConnell Eleanor , Lee Chiyoung , Tsumura Hideyo , Wei Sijia , Pan Wei 
Published: December 2020

Abstract
Older adults with dementia are more prone to have adverse health outcomes following hip fracture surgery. However, individuals with dementia and hip fracture are older and have more co-morbidities; these baseline differences can bias estimates of the influence of dementia. This study aims to investigate how dementia influences disposition, mortality rates and readmission rates at 365 days after hip surgery in older adults over age 65, after accounting for baseline factors such as socioeconomic status, health behaviors, co-morbidities, and type of hip fracture repair. A cohort of 1172 patients who had hip fracture surgery between October 2015 and December 2018 was extracted from electronic health records; among those, 376 had a diagnosis of dementia. Inverse probability of treatment weighting using propensity scores method was used to reduce the influence of factors that may confound the relationship between dementia status and hip surgery outcomes. Logistic regression was applied to estimate influences on discharge disposition and Cox proportional hazards model for one-year mortality. To account for competing risk of death, a Fine and Gray regression model was used to calculate subdistribution hazard ratios of readmission. Disparities in long-term surgical outcomes in patients with dementia were found. Results show that dementia was a significant predictor for being discharged to facilities (OR=1.92, 95% CI 1.09, 3.39, p=.025), death (HR=1.98, 95% CI 1.50-2.62, p&lt;.0001) and being readmitted within one year (HR=1.31, 95% CI 1.15-1.50, p&lt;.0001). These findings call for more efforts in developing effective multidisciplinary perioperative assessments and rehabilitation for patients with dementia.
Pain Intensity and Unpleasantness in People with Vascular Dementia: A Cross Sectional Study
Authors: Humbel Angela , Cowan R , Dietrich Mary , Iversen Wm Larkin , Atalla Sebastian , Moss Karen , Englehart Sydney , Monroe Todd 
Published: December 2020

Abstract
Pain is a multidimensional sensory and affective experience. People with Vascular Dementia (VaD) experience pain more intensely and have negative emotional responses. Further investigation is needed to understand the neurobiology of pain in VaD. We used experimental thermal pain in a cross-sectional design to determine if adults (age&gt;64) with probable VaD experience increased pain intensity and increased pain unpleasantness during “mild” and “moderate” thermal pain. The final sample included 46 sex- and age-matched adults (23 VaD; 12 female) and controls (23 cognitively intact; 12 female) with an average age of 76.5 years (SD=7.5). Participants reported no daily analgesic use. We used a thermode placed on the thenar eminence to assess temperatures perceived as mild and moderate pain (°C) followed by unpleasantness ratings (0-20 scale). We assessed cognition and depression with the Mini-Mental State Exam (MMSE) and the Geriatric Depression Scale. After controlling for depression, and relative to controls, there was no statistically significant difference in the temperature at which people with VaD perceived mild or moderate pain (p = .086; Cohen’s d: mild=0.55, moderate=0.27). However, there was a statistically significant effect of VaD status on pain unpleasantness (p = .003). People with VaD reported mild and moderate pain as more unpleasant than controls (Cohen’s d = 0.79 and 0.60, respectively). Findings support previous work that people with VaD are at risk of experiencing more pain. Assessing pain intensity and affect can avoid under-treated pain in those with VaD.
Sedentary Behavior, Brain-Derived Neurotrophic Factor (BDNF), and Brain Structure in Midlife: A Brain MRI Study
Authors: Zhang Xuan , Gaughan Denise , Qiu Chengxuan , Meirelles Osorio , Launer Lenore 
Published: December 2020

Abstract
Long sedentary time (ST) is associated with poor brain health but the underlying mechanisms are unclear. Studies suggest exercise increases BDNF levels, and that low BDNF levels are associated with cognitive impairment. Limited population-based studies have examined associations among sedentary behavior (SB), BDNF, and brain structures. Here we explore the mediation and interaction effect of BDNF in the association of SB to brain measures. We included 612 participants from the MRI sub-study of the Coronary Artery Risk Development in Young Adults who had plasma BDNF and SB data at the Year 25 examination. SB was estimated by self-reported average ST hours/day spent sitting while watching television, using computers, and riding transportation. Outcome measures were total and selected brain volumes in cubic centimeters (cc). ST was categorized into quartiles. We used general linear regression to examine the following associations, adjusting for age, sex, race, and intracranial volume: Interactions between BDNF and ST on MRI; ST and MRI; ST and BDNF; BDNF and MRI; and ST, BDNF, and MRI. People in the upper 25%ile ST (&gt;8.4 hours/day) had a decreased TB volume of 12.2 cc (p=0.01) compared to the lower 25%ile (&lt;4.3 hours/day). Neither ST nor brain measures were associated with BDNF (p&gt;0.05). Instead, BDNF interacted with ST for TB and WM (p &lt; 0.03): The difference of brain volumes between the upper and lower 25%ile decreased with increasing BDNF levels. Accordingly, higher BDNF levels may protect brain function in the middle-aged and potentially older populations with a sedentary lifestyle.