bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental and computational studies of imidazolium based ionic liquid 1-methyl- 3-propylimidazolium iodide on mild steel corrosion in acidic solution
Authors: Parveen Gulista , Bashir Sumayah , Thakur Abhinay , Saha Sourav Kr , Banerjee Priyabrata , Kumar Ashish 
Published: November 2019

AbstractCorrosion inhibitive property of ionic liquid 1-Methyl-3-propylimidazolium iodide (MPII) on Mild Steel in 1 M H2SO4was investigated by experimental and computational Studies. The inhibition efficiency of inhibitor MPII at various concentrations, temperature and time duration were studied by gravimetric measurements, potentiodynamic polarization techniques, electrochemical impedance spectroscopy (EIS), surface studies and computational studies. The results from potentiodynamic polarization studies revealed that inhibitor 1-Methyl- 3-propylimidazolium iodide acts as a mixed type inhibitor with a high inhibition efficiency of 91% at 298 K. Adsorption of the inhibitor on the surface of mild steel follows the Langmuir adsorption isotherm. The mechanism of adsorption was also validated by quantum chemical studies. Morphology and topography of the Mild Steel surface with and without the inhibitor were investigated by SEM. Thermodynamic parameters for adsorption like adsorption equilibrium (Kads),ΔHads,ΔSads,Free energy of adsorption i.e. ΔGadswere also calculated so as to project the mechanism of adsorption. Computational data obtained from the Density functional theory (DFT) were used to acquire detailed theoretical insights. Appreciably Electrochemical impedance spectroscopy, Molecular dynamic simulation and quantum chemical calculation confirms the interaction of inhibitor with metal which leads to increases in inhibition efficiency.
Synthesis, luminescence and energy transfer of Ca3GdNa(PO4)3F: Ce3+, Tb3+ phosphor with novel apatite structure
Authors: Xie Lin-Yan , Zhuo Ning-Ze , Zhang Na , Du Wen-Hui , Zhu Yue-Hua , Cheng Shao-Wen , Wang Hai-Bo 
Published: November 2019

Abstract
A series of Ce3+/Tb3+ singly doped and Ce3+, Tb3+ co-doped Ca3GdNa(PO4)3F phosphors were synthesized via high temperature solid-state reaction in a reductive atmosphere. The crystal, luminescence properties, energy transfer mechanism and thermal stability of the samples were investigated in detail. The Ce3+ doped phosphors can be excited in the range from 250 to 330 nm. The Ce3+,Tb3+ co-doped phosphors exhibit characteristic emission of Ce3+ and Tb3+ simultaneously under the excitation of 301 nm. In addition, the energy transfer efficiency from Ce3+ to Tb3+ reaches as high as 78.6% when the doping amount of Tb3+ is 0.20. The mechanism of energy transfer between Ce3+ and Tb3+ ions is demonstrated to be a dipole−dipole interaction. The luminescence characteristics show that this phosphor can be a platform for modeling a new phosphor and application in the solid-state lighting field.
Relationship of amyloid-β1–42 in blood and brain amyloid: Ginkgo Evaluation of Memory Study
Authors: Lopez Oscar L , Klunk William E , Mathis Chester A , Snitz Beth E , Chang Yuefang , Tracy Russell P , Kuller Lewis H 
Published: November 2019

AbstractA blood test that predicts the extent of amyloid plaques in the brain and risk of Alzheimer’s disease would have important benefits for the early identification of higher risk of dementia and Alzheimer’s disease and the evaluation of new preventative therapies. The goal of this study was to determine whether plasma levels of amyloid-β1–42, 1–40 and the amyloid-β1–42/1–40 ratio among participants in the Pittsburgh centre of the Ginkgo Evaluation of Memory Study were related to the extent of brain fibrillar amyloid plaques measured in 2009 using Pittsburgh compound-B PET imaging, hippocampal volume, cortical thickness in the temporal lobe and white matter lesions. There were 194 participants who had Pittsburgh compound-B measurements in 2009 with the mean age of 85 years; 96% were white and 60% men. Pittsburgh compound-B positivity was defined as a standardized uptake value ratio of ≥1.57. Amyloid-β in blood was measured using a sandwich enzyme-linked immunosorbent assay developed by Eli Lilly and modified at the University of Vermont. All participants were nondemented as of 2008 at the time of study close out. The study sample included 160 with blood samples drawn in 2000–02 and 133 from 2009 and also had brain amyloid measured in 2009. All blood samples were analysed at the same time in 2009. Plasma amyloid-β1–42 was inversely related to the percent Pittsburgh compound-B positive (standardized uptake value ratio ≥1.57), β −0.04, P = 0.005. Practically all participants who were apolipoprotein-E4 positive at older ages were also Pittsburgh compound-B positive for fibrillar amyloid. Among apolipoprotein-E4-negative participants, quartiles of amyloid-β1–42 were inversely related to Pittsburgh compound-B positivity. In multiple regression models, plasma amyloid-β1–42 measured in 2000–02 or 2009 were significantly and inversely related to Pittsburgh compound-B positivity as was the amyloid-β1–42/1–40 ratio. There was a 4-fold increase in the odds ratio for the presence of Pittsburgh compound-B positivity in the brain in 2009 for the first quartile of amyloid-β1–42 as compared with the fourth quartile in the multiple logistic model. This is one of the first longitudinal studies to evaluate the relationship between amyloid-β1–42 in the blood and the extent of brain amyloid deposition measured by PET imaging using Pittsburgh compound-B. Our findings showed that remote and recent low plasma amyloid-β1–42 levels were inversely associated with brain amyloid deposition in cognitively normal individuals. However, changes in plasma amyloid-β1–42 over time (8 years) were small and not related to the amount of Pittsburgh compound-B.
Firms’ Price, Cost and Activity Expectations: Evidence from Micro Data
Authors: Boneva Lena , Cloyne James , Weale Martin , Wieladek Tomasz 
Published: November 2019

Abstract
Firms’ expectations play a central role in modern macroeconomic models, but little is known empirically about them. Using panel data on manufacturing firms’ expectations about prices and wage rates, new orders, employment and unit costs for the United Kingdom, we document a range of stylised facts about firms’ expectations and their determinants. There is wide dispersion of expectations across firms. Firms' expectations are influenced by both firm-specific factors and macroeconomic factors. We find a significant connection between past expected price and wage increases and their out-turns. Firms’ expectations are, however, clearly not rational.
Impact of preoperative liver dysfunction on outcomes in patients with left ventricular assist devices
Authors: Yalcin Yunus C , Muslem Rahatullah , Veen Kevin M , Soliman Osama I , Manintveld Olivier C , Darwish Murad Sarwa , Kilic Ahmet , Constantinescu Alina A , Brugts Jasper J , Alkhunaizi Fatimah , Birim Ozcan , Tedford Ryan J , Bogers Ad J J C , Hsu Steven , Caliskan Kadir 
Published: November 2019

Abstract

OBJECTIVES
We evaluated the impact of preoperative liver function on early and 1-year postoperative outcomes in patients supported with a left ventricular assist device (LVAD) and subsequent evolution of liver function markers.

METHODS
A retrospective multicentre cohort study was conducted, including all patients undergoing continuous-flow LVAD implantation. The Model for End-stage Liver Disease (MELD) score was used to define liver dysfunction.

RESULTS
Overall, 290 patients with an LVAD [78% HeartMate II, 15% HVAD and 7% HeartMate 3, mean age 55 (18), 76% men] were included. Over 40 000 measurements of liver function markers were collected over a 1-year period. A receiver operating characteristic curve analysis for the 1-year mortality rate identified the optimal cut-off value of 12.6 for the MELD score. Therefore, the cohort was dichotomized into patients with an MELD score of less than or greater than 12.6. The early (90-day) survival rates in patients with and without liver dysfunction were 76% and 91% (P = 0.002) and 65% and 90% at 1 year, respectively (P &lt; 0.001). Furthermore, patients with preoperative liver dysfunction had more embolic events and more re-explorations. At the 1-year follow-up, liver function markers showed an overall improvement in the majority of patients, with or without pre-LVAD liver dysfunction.

CONCLUSIONS
Preoperative liver dysfunction is associated with higher early 90-day and 1-year mortality rates after LVAD implantation. Furthermore, liver function improved in both patient groups. It has become imperative to optimize the selection criteria for possible LVAD candidates, since those who survive the first year show excellent recovery of their liver markers.
Genetic diversity of Legionella pcs and pmtA genes and the effect of utilization of choline by Legionella spp. on induction of proinflammatory cytokines
Authors: Palusińska-Szysz Marta , Szuster-Ciesielska Agnieszka , Janczarek Monika , Wdowiak-Wróbel Sylwia , Schiller Jürgen , Reszczyńska Emilia , Gruszecki Wiesław I , Fuchs Beate 
Published: November 2019

ABSTRACT
Legionella species synthesize phosphatidylcholine (PC) in two independent pathways: the three-step methylation of phosphatidylethanolamine PMT pathway and the one-step PCS pathway, in which the Pcs enzyme catalyzes the reaction between choline and CDP-diacylglycerol to form PC. Legionella pcs genes encode highly hydrophobic proteins with phosphatidylcholine synthase activity, which contain up to eight transmembrane helices with N- and C-termini located inside the bacterial cell. The comparative analysis of nucleotide sequences of pcs showed that these genes share high sequence identity among members of the Legionellaceae family. Legionella pmtA genes involved in the PMT pathway encoded small cytosolic proteins with putative phosphatidylethanolamine N-methyltransferase activity. The pmtA genes identified in Legionella species had lower sequence identity to each other than the pcs genes. The phylogenetic tree constructed based on the pcs and pmtA gene sequences showed phylogenetic relatedness between Legionella spp. and other bacteria. The utilization of extracellular choline by the four Legionella species leads to changes not only in the lipid components but also in proteins, and the interactions between these components lead to changes in cell surface properties, which result in a decline in induction of proinflammatory cytokines (TNF-α and IL-6).
Relative Quasimaps and Mirror Formulae
Authors: Battistella Luca , Nabijou Navid 
Published: November 2019

Abstract
We construct and study the theory of relative quasimaps in genus zero, in the spirit of Gathmann. When $X$ is a smooth toric variety and $Y$ is a smooth very ample hypersurface in $X$, we produce a virtual class on the moduli space of relative quasimaps to $(X,Y)$, which we use to define relative quasimap invariants. We obtain a recursion formula which expresses each relative invariant in terms of invariants of lower tangency, and apply this formula to derive a quantum Lefschetz theorem for quasimaps, expressing the restricted quasimap invariants of $Y$ in terms of those of $X$. Finally, we show that the relative $I$-function of Fan–Tseng–You coincides with a natural generating function for relative quasimap invariants, providing mirror-symmetric motivation for the theory.
Refugees’ Debit Cards, Subjectivities, and Data Circuits: Financial-Humanitarianism in the Greek Migration Laboratory
Authors: Tazzioli Martina 
Published: November 2019

AbstractThis paper focuses on the financialization of refugee humanitarianism in Greece, bringing attention to the Cash Assistance Programme, which is the first European Union–funded project in Europe providing financial support to asylum seekers, coordinated by the United Nations High Commissioner for Refugees. This program consists of the delivery and monthly recharge of prepaid debit cards to asylum seekers inside hotspots and refugee camps. The article deals with three aspects. First, it analyzes the political technologies of government that this system enforces, bringing attention to the modes for governing refugee populations in transit. Second, it considers the data circulation activities that are connected to it, analyzing what I call the circuits of financial humanitarianism and explaining in detail how data is shared between the different actors involved (banks, IGOs, Greek authorities, and NGOs). Third, it explores the specific effects of subjectivation produced by this temporary and exclusionary mechanism of financial support, together with the forms of value extraction that stem from it. The paper argues that far from generating financial inclusion, techniques of financialization of humanitarianism should be situated among measures for regaining control over unruly movements, predicated upon exclusionary and temporary mechanisms of government.
Impact of bacterial species and baseline resistance on fosfomycin efficacy in urinary tract infections
Authors: Abbott Iain J , Dekker Jordy , van Gorp Elke , Wijma Rixt A , Raaphorst Merel N , Klaassen Corné H W , Meletiadis Joseph , Mouton Johan W , Peleg Anton Y 
Published: November 2019

Abstract

Objectives
To assess the antibacterial effects of a single 3 g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model.

Methods
An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure (Cmax = 1984 mg/L and Tmax = 7.5 h) was validated by LC-MS/MS. Pharmacodynamic responses of 24 E. coli and 20 K. pneumoniae clinical isolates were examined (fosfomycin MIC ≤0.25–128 mg/L). Mutant prevention concentration (MPC), fosfomycin heteroresistance, fosfomycin resistance genes and fosA expression were examined. Pathogen kill and emergence of high-level resistance (HLR; MIC &gt;1024 mg/L) were quantified.

Results
Following fosfomycin exposure, 20 of 24 E. coli exhibited reductions in bacterial counts below the lower limit of quantification without regrowth, despite baseline fosfomycin MICs up to 128 mg/L. Four E. coli regrew (MIC = 4–32 mg/L) with HLR population replacement. At baseline, these isolates had detectable HLR subpopulations and MPC &gt;1024 mg/L. All E. coli isolates were fosA negative. In contrast, 17 of 20 K. pneumoniae regrew post exposure, 6 with emergence of HLR (proportion = 0.01%–100%). The three isolates without regrowth did not have a detectable HLR subpopulation after dynamic drug-free incubation. All K. pneumoniae had MPC &gt;1024 mg/L and were fosA positive. WGS analysis and fosA expression failed to predict fosfomycin efficacy.

Conclusions
E. coli and K. pneumoniae isolates demonstrate discrepant responses to a single fosfomycin dose in a dynamic bladder infection in vitro model. Treatment failure against E. coli was related to an HLR subpopulation, not identified by standard MIC testing. Activity against K. pneumoniae appeared limited, regardless of MIC testing, due to universal baseline heteroresistance.
Attributable nephrotoxicity of vancomycin in critically ill patients: a marginal structural model study
Authors: Arnaud Frederico Carlos de Sousa , Libório Alexandre Braga 
Published: November 2019

Abstract

Background
Although vancomycin nephrotoxicity is recognizable, critically ill patients have other potential reasons for acute kidney injury (AKI) and determining its attributable nephrotoxic risk in this population can be cumbersome.

Objectives
To determine the risk of AKI attributable to vancomycin, controlling for baseline and time-dependent confounders.

Methods
Time-fixed and daily time-varying variables were extracted from a large public database. The exposures analysed were: (i) IV vancomycin; (ii) serum trough level greater than 15 and 20 mg/L; and (iii) concomitant exposure to vancomycin and piperacillin/tazobactam or other antipseudomonal β-lactams. Censoring and exposure inverse probability of treatment weighting were calculated. Marginal structural models were plotted to evaluate AKI, severe AKI (stage 2/3) and need of renal replacement therapy (RRT).

Results
A total of 26 865 patients were included; 19.7% received vancomycin during ICU stay. After adjusting for fixed and time-variable confounders, vancomycin exposure was associated with AKI (HR = 1.24, 95% CI = 1.09–1.38), but not with severe AKI or need of RRT (HR = 1.05, 95% CI = 0.91–1.23 and HR = 0.97, 95% CI = 0.74–1.29, respectively). A serum trough level greater than 20 mg/L was associated with AKI (HR = 1.90, 95% CI = 1.52–2.30) and severe AKI (HR = 1.69, 95% CI = 1.31–2.19), but showed no statistically significant association with need of RRT (HR = 1.48, 95% CI = 0.92–2.56). The vancomycin + piperacillin/tazobactam combination was not associated with a greater risk than vancomycin alone.

Conclusions
The attributable nephrotoxicity of vancomycin in critically ill patients is significantly lower than previously suggested and severe AKI is related to vancomycin only when trough serum levels are greater than 20 mg/L.
Red foxes (Vulpes vulpes) and coyotes (Canis latrans) in an urban landscape: prevalence and risk factors for disease
Authors: Pluemer Meghan , Dubay Shelli , Drake David , Crimmins Shawn , Veverka Tessa , Hovanec Holly , Torkelson Miranda , Mueller Marcus 
Published: November 2019

AbstractUrbanized areas contain fragmented landscapes and abundant resources, resulting in concentrated and increased wildlife populations in relatively close contact with other wildlife species, humans, and their domestic pets, thereby posing novel disease risks and facilitating inter-specific disease transmission. We trapped and radio-collared 15 red foxes (Vulpes vulpes) and 14 coyotes (Canis latrans) in the urban landscape of Madison, Wisconsin, to determine the prevalence of disease among these canids and to examine how these canids were using the landscape. Using Fisher’s exact probability tests, we found that coyotes had a significantly higher seroprevalence of Lyme disease (P = 0.002) and a higher prevalence of canine heartworm disease (P = 0.02) than foxes. Red foxes did not select specific habitat types in the urban landscape, but coyotes selected for forest and grass cover types, and avoided developed sites. Understanding the prevalence of disease in urban canid populations is important because diseases affecting urban canids cause morbidity and mortality and are transmissible to domestic dogs, and vice versa. Additionally, urban canids may serve as sentinels for zoonotic diseases such as Lyme disease and leptospirosis.
Losing connection: the modal logic of definable link deletion
Authors: Li Dazhu 
Published: November 2019

Abstract
In this article, we start with a two-player game that models communication under adverse circumstances in everyday life and study it from the perspective of a modal logic of graphs, where links can be deleted locally according to definitions available to the adversarial player. We first introduce a new language, semantics and some typical validities. We then formulate a new type of first-order translation for this modal logic and prove its correctness. Then, a novel notion of bisimulation is proposed that leads to a characterization theorem for the logic as a fragment of first-order logic, and a further investigation is made of its expressive power against hybrid modal languages. Next, we discuss how to axiomatize this logic of link deletion, using dynamic-epistemic logics as a contrast. Finally, we show that our new modal logic lacks both the tree model property and the finite model property and that its satisfiability problem is undecidable.
The overarching framework of core-collapse supernova explosions as revealed by 3D fornax simulations
Authors: Burrows Adam , Radice David , Vartanyan David , Nagakura Hiroki , Skinner M Aaron , Dolence Joshua C 
Published: November 2019

ABSTRACT
We have conducted 19 state-of-the-art 3D core-collapse supernova simulations spanning a broad range of progenitor masses. This is the largest collection of sophisticated 3D supernova simulations ever performed. We have found that while the majority of these models explode, not all do, and that even models in the middle of the available progenitor mass range may be less explodable. This does not mean that those models for which we did not witness explosion would not explode in Nature, but that they are less prone to explosion than others. One consequence is that the ‘compactness’ measure is not a metric for explodability. We find that lower-mass massive star progenitors likely experience lower-energy explosions, while the higher-mass massive stars likely experience higher-energy explosions. Moreover, most 3D explosions have a dominant dipole morphology, have a pinched, wasp-waist structure, and experience simultaneous accretion and explosion. We reproduce the general range of residual neutron-star masses inferred for the galactic neutron-star population. The most massive progenitor models, however, in particular vis à vis explosion energy, need to be continued for longer physical times to asymptote to their final states. We find that while the majority of the inner ejecta have Ye = 0.5, there is a substantial proton-rich tail. This result has important implications for the nucleosynthetic yields as a function of progenitor. Finally, we find that the non-exploding models eventually evolve into compact inner configurations that experience a quasi-periodic spiral SASI mode. We otherwise see little evidence of the SASI in the exploding models.
Eliminating artefacts in polarimetric images using deep learning
Authors: Paranjpye D , Mahabal A , Ramaprakash A N , Panopoulou G V , Cleary K , Readhead A C S , Blinov D , Tassis K 
Published: November 2019

ABSTRACTPolarization measurements done using Imaging Polarimeters such as the Robotic Polarimeter are very sensitive to the presence of artefacts in images. Artefacts can range from internal reflections in a telescope to satellite trails that could contaminate an area of interest in the image. With the advent of wide-field polarimetry surveys, it is imperative to develop methods that automatically flag artefacts in images. In this paper, we implement a Convolutional Neural Network to identify the most dominant artefacts in the images. We find that our model can successfully classify sources with 98 per cent true positive and 97 per cent true negative rates. Such models, combined with transfer learning, will give us a running start in artefact elimination for near-future surveys like WALOP.
Simultaneous Millimetre-wave and X-ray monitoring of the Seyfert galaxy NGC 7469
Authors: Behar Ehud , Kaspi Shai , Paubert Gabriel , Billot Nicolas , Peretz Uria , Baldi Ranieri D , Laor Ari , Kaastra Jelle , Mehdipour Missagh 
Published: November 2019

ABSTRACT
We report on daily monitoring of the Seyfert galaxy ngc 7469, around 95 and 143 GHz, with the iram (Institut de Radioastronomie Millimetrique) 30- m radio telescope, and with the Swift X-ray and UV/optical telescopes, over an overlapping period of 45 d. The source was observed on 36 d with iram, and the flux density in both mm bands was on average ∼10 mJy, but varied by $\pm 50{{\ \rm per\ cent}}$, and by up to a factor of 2 between days. The present iram variability parameters are consistent with earlier monitoring, which had only 18 data points. The X-ray light curve of ngc 7469 over the same period spans a factor of 5 in flux with small uncertainties. Similar variability in the mm band and in the X-rays lends support to the notion of both sources originating in the same physical component of the active galactic nucleus (AGN), likely the accretion disc corona. Simultaneous monitoring in eight UV/optical bands shows much less variability than the mm and X-rays, implying this light originates from a different AGN component, likely the accretion disc itself. We use a tentative 14-d lag of the X-ray light curve with respect to the 95 GHz light curve to speculate on coronal implications. More precise mm-band measurements of a sample of X-ray-variable AGN are needed, preferably also on time-scales of less than a day where X-rays vary dramatically, in order to properly test the physical connection between the two bands.