bluuebunny/crossref_metadata_2025_split huggingface dataset:
Astım Hastalığında Antioksidanların Önemi
Authors: Duman Erdem , Demir Halit 
Published: December 2024

Astım, her yaş grubunu etkileyen kronik bir solunum yolu hastalığıdır. Genellikle inflamasyon ve aşırı duyarlılık ile karakterizedir. Inflamasyon, dokularda oluşan hasara karşı gelişen yanıtı ifade eder. Serbest radikallerin neden olduğu oksidatif stres, astımın patogenezine katkıda bulunmaktadır. İnflamasyon, astım, obezite ve diyabet gibi hastalıkların gelişiminde rol oynar. Astımlı kişilerde insülin direnci ve glikoz metabolizması sorunları oluşabilir. Astım hastalığının şiddeti ve inflamasyon ile ilişkili bir risk faktörü olan beslenme, antioksidan özellikli besin ögelerinden zengin anti-inflamatuvar diyetlerle tedavi edilebilmektedir. Antioksidanlar hücre hasarını önler ve serbest radikalleri nötralize eder. Omega-3 yağ asitleri, D vitamini ve probiyotikler gibi bileşenler içeren anti-inflamatuvar diyetler, astım gibi inflamasyon kaynaklı hastalıklara olumlu etkiler sağlayabilir. Bu nedenle, diyet antioksidanlarının alımı artırılmalıdır.
Sonuç olarak, astım hastalarında önleyici ve koruyucu olarak antioksidan içerikli gıdalar veya takviyeler kullanılabilir.
Behçet Hastalığında Beslenmenin Önemi
Authors: Aka Nihat 
Published: December 2024

Behçet hastalığı, ağız ve genital bölgede ülser, göz problemleri, cilt lezyonları, gastrointestinal ve nörolojik sorunlar, artrit, vasküler komplikasyonlar ve pulmoner endikasyonlar gibi çeşitli semptomlarla ortaya çıkar. Behçet hastalığının etiyolojisi henüz net değildir. Genetik olarak yatkın ve duyarlı bireylerde genetik veya enfeksiyöz faktörler tarafından tetiklenen otoinflamatuar ve otoimmün bir özellik olarak kabul edilir. Behçet sendromunda hastalık alevlenmeleri tahmin edilemese de besinler, stres, mukozal travma, adet, diş çekimi ve enfeksiyonlar dahil olmak üzere çeşitli potansiyel tetikleyiciler bildirilmiştir . Behçet sendromunun nadirliği göz önüne alındığında, bu duruma özgü belirlenmiş bir beslenme protokolü yoktur. Ancak hastaların beslenme durumu, kronik bir inflamatuar bozukluk olarak sınıflandırılması göz önüne alındığında, sendromun klinik sunumu, devam eden inflamasyon ve ilaç kullanımından etkilenir. Hastaların gıda tüketiminin başarılı bir şekilde yönetilmesi remisyonu başlatmalı ve sürdürmeli ve hastaların yaşam kalitesini iyileştirmelidir. Sonuç olarak, bu faktörler genellikle iştahta, gastrointestinal fonksiyonda ve metabolik durumda değişikliklere neden olur . Bu nedenle, beslenme durumunun düzenli olarak izlenmesi son derece önemlidir.
HOSPITALIDADE AO PÚBLICO LGBTQIAPN+ EM ESPAÇOS DE LAZER NA BAIXADA VERDE/RJ
Authors: Sena de Lima Gabriella , Fogaça Isabela de Fátima 
Published: December 2024

Hospitalidade e turismo se relacionam com o bem-receber e o entreter os indivíduos. No entanto, muitos grupos sofrem preconceitos e não são bem recebidos em determinados lugares turísticos. Na perspectiva de que a hospitalidade deve ser uma constante em qualquer lugar e junto a qualquer indivíduo, esta pesquisa visa analisar a hospitalidade dos espaços de lazer voltados para o público LGBTQIAPN+ que reside ou frequenta a Baixada Verde, região turística do Rio de Janeiro. A metodologia utilizada envolveu a aplicação de um questionário virtual, pesquisa bibliográfica e documental. Como resultado, o público alvo considera que a região possui poucos espaços hospitaleiros; sentem falta de empreendimentos que declarem apoio aos LGBT+, de empreendedores e funcionários da comunidade atuando nesses espaços e equipe qualificada para atender este público.
EDUCAÇÃO INCLUSIVA: DA LEGITIMAÇÃO NACIONAL AO CONTEXTO REGIONAL, UMA ANÁLISE, DA ESCOLA PÚBLICA EM LIMOEIRO DO AJURU- PARÁ.
Authors: Gomes Rosivalda Pimentel , Castro Veridiana Valente Pinheiro 
Published: December 2024

O presente artigo realiza um estudo bibliográfico de cunho observacional para verificar como ocorre o processo de inclusão dos estudantes com deficiência no ensino regular da Educação básica. Dentre muitos aspectos relacionados a esta temática, elencou-se a questão do surgimento do processo de ensino inclusivo nas escolas regulares brasileiras, e mostrou-se como foi difícil a inclusão do ensino nas escolas públicas. Para análise desta pesquisa, consideramos uma escola da Rede Pública de ensino, localizada na cidade de Limoeiro do Ajuru, estado do Pará. Com isso, busca se destacar os primeiros surgimentos da educação inclusiva no Brasil e partir daí colocamos como está modalidade de educação surgiu no cenário educacional das escolas públicas brasileiras. Em seguida mostramos como está sendo trabalhado a educação para as crianças com deficiência na escola em questão. Foi analisada também a questão das crianças portadores de deficiência auditiva e as deficiências intelectuais pois acreditamos que estas duas são comuns entre os estudantes. Colocamos os resultados desta pesquisa dentro do tópico dados da pesquisa. Então, espera-se que esta pesquisa possa ajudar a melhorar a literatura pertinente ao tema além de mostrar que as crianças deficientes têm os mesmos direitos de acesso a uma educação de qualidade, basta os envolvidos com o processo educacional querer fazer.
OPTIMALISASI BAKAT DAN POTENSI KEBAIKAN DALAM PERSPEKTIF AL-QUR'AN: ANALISIS QS. AN-NAHL AYAT 78, QS. AS-SYAMS AYAT 8-10, DAN QS. AL-ISRA AYAT 32
Authors: Rozaq Muhammad , Fahmi Tubagus , Nur Rohmah Isnaini , Rahmawati Ana 
Published: December 2024

This article presents a comparative analysis of honing different talents and potential for goodness, specifically comparing various methods or approaches to developing and maximizing an individual's talents and potential for goodness. The research method used is library research. The findings indicate that humans have the potential for both good and bad tendencies. The moral teachings in the Quran emphasize the development of good traits and the avoidance of bad ones, as explained in Ibn Kathir's commentary on the purity and corruption of a person’s inner self. Humans possess two tendencies that differentiate between good and bad. Allah provides imbalance and punishment in accordance with human choices. Acts of adultery and murder are described in the Quran as grave wrongdoings that must be avoided and controlled by humans to prevent their negative consequences.

Keywords: Talent, potential, character

Artikel ini menyajikan perbandingan analisis tentang mengasah bakat dan potensi kebaikan yang berbeda, yaitu menyajikan suatu perbandingan yang menganalisis cara atau metode yang berbeda dalam mengembangkan atau memaksimalkan bakat serta potensi kebaikan seseorang. Metode penelitian yang diterapkan adalah studi kepustakaan (library research). Hasil penelitian ini adalah Manusia mempunyai kemungkinan serta kecenderungan baik dan buruk. Pelajaran moral dalam Al-Quran fokus pada pertumbuhan sifat baik dan menjauhi sifat buruk, seperti yang dijelaskan dalam penjelasan Ibnu Kasir tentang kesucian dan kekotoran batin seseorang. Manusia mempunyai dua kecenderungan yang dapat membedakan antara yang baik dan yang buruk. Allah memberikan ketidakseimbangan dan hukuman sesuai dengan keputusan manusia. Perbuatan zina dan pembunuhan dijelaskan dalam Al-Quran sebagai perilaku yang sangat buruk yang harus dijauhi dan dikendalikan manusia demi menghindari konsekuensi negatifnya.

Kata kunci: Bakat, potensi, karakter
Los Elementos Socioculturales en la Enseñanza del Inglés con Fines Médicos
Authors: Naranjo Corría Rebeca , Santiesteban Naranjo Ernan , Ramírez Lozada Haydée , Suárez Lezcano José 
Published: December 2024

Esta investigación parte de la necesidad de propiciar el desarrollo de elementos socioculturales a partir del proceso de enseñanza aprendizaje en idioma inglés con fines médicos en estudiantes de cuarto año de Medicina, en la Universidad de Ciencias Médicas de las Tunas, Cuba. En el proceso de investigación se utilizaron métodos de nivel empírico y teórico -- histórico-lógico, triangulación de la información, análisis y síntesis, hipotético-deductivo, la entrevista, la prueba pedagógica, y el enfoque sistémico- estructural. La aplicación de los referidos métodos posibilitó la elaboración de una estrategia didáctica dinámico-participativa para la enseñanza de los elementos socioculturales de los pueblos de habla inglesa, desde el inglés con fines específicos. La estrategia otorga el papel protagónico al estudiante, el que a partir de un esquema de contenido y de forma, exterioriza en contextos reales la apropiación de los elementos socioculturales de dichos pueblos. La aplicación de esta propuesta posibilitó el desplazamiento de la Zona de Desarrollo Próximo de los estudiantes, al motivarlos para el aprendizaje de la lengua y su cultura; eventualmente se evidenció en la transformación de rasgos negativos de su comportamiento.Palabras clave: elementos socioculturales; inglés con fines médicos; enseñanza. AbstractThis research departs from the need to promote the development of cultural elements from the very process of learning the English Language for medical purposes in fourth year medical students, in the University of Medical Sciences of Las Tunas, Cuba. In the research process we used empirical and theoretical methods —historical- logical, triangulation of information, analysis and synthesis, hypothetical-deductive, the interview, the educational testing, and the systemic-structural approach. The application of the aforementioned methods made possible the development of a dynamic-participatory teaching strategy to teach the sociocultural elements of the English-speaking peoples from the English for specific purposes. The strategy gives the student a starring role, who from a scheme of content and form, externalizes in real contexts the appropriation of the socio-cultural elements of these peoples. The implementation of this proposal made the displacement of the students´ Zones of Proximal Development possible, by motivating them to learn the language and culture; the transformation of negative traits of their behavior was eventually evidenced.Keywords: sociocultural elements; English for Medical Purposes; teaching.
El Aprendizaje Cooperativo en los Estudiantes de Diseño Gráfico de la Pontificia Universidad Católica del Ecuador, Sede Esmeraldas
Authors: Vásquez Coisme Ladys 
Published: December 2024

Para identificar las formas de aplicación del aprendizaje cooperativo en los estudiantes de diseño gráfico, se realizó un estudio longitudinal retrospectivo, cuasi-experimental, cuanti-cualitativo y analítico en la Escuela de Diseño Gráfico de la Pontifica Universidad Católica del Ecuador, Sede Esmeraldas (PUCESE), en el período comprendido en mayo de 2014 y febrero de 2015. La población la conformaron 65 estudiantes, matriculados en 2, 3, 5, 6 y 7 semestres y seis docentes de la especialidad. Para la recolección de los datos se utilizaron el cuestionario y la ficha de observación. Los resultados obtenidos demostraron que los docentes confunden el trabajo en equipo con aprendizaje cooperativo y se enfocan en enseñar un contenido, pero no en desarrollar alguna competencia. El 40% de los estudiantes tiene una actitud desinteresada. Se diseñó un instructivo llamado Cooperando Aprendo Más y Desarrollo Competencias para aplicar el aprendizaje cooperativo de forma correcta, el que se utilizó en un grupo de 12 estudiantes y que demostró la aplicación del aprendizaje cooperativo y el desarrollo de la competencia disciplinar del contenido establecido en esa clase.Palabras clave: aprendizaje cooperativo; competencia; diseño gráfico AbstractA retrospective, quasi-experimental, quantitative-qualitative and analytical study was carried out at the School of Graphic Design of the Pontifical Catholic University of Ecuador, Esmeraldas Campus (PUCESE) to identify cooperative learning applications in Graphic Design students. The study was done in the period between May 2014 and February 2015. The population was made up of 65 students, enrolled in 2, 3, 5, 6 and 7 semesters and six teachers of the specialty. For the collection of the data, a questionnaire and an observation sheet were used. The results showed that teachers confuse teamwork with cooperative learning and focus on teaching content, but not on developing any competences. 40% of the students have a disinterested attitude. An instruction called Cooperating I Learn More and Develop Competences was designed to apply cooperative learning correctly, which was used in a group of 12 students and which demonstrated the application of cooperative learning and the development of the disciplinary competence of the content established in that class.Keywords: Cooperative learning; competence; graphic design
Perancangan Virtual Private Network Dengan Metode PPTP Menggunakan Mikrotik
Authors: Arfind Reza , Supendar Hendra , Fahlapi Riza 
Published: December 2024

Perkembangan usaha tekstil sudah semakin meluas, sehingga dalam menopang efektifitas dalam pelaksanaannya membutuhkan koneksi agar saling terhubung antar satu tempat dengan cabang perusahaan lainnya, namun dalam pelaksanaannya perusahaan perlu adanya jaringan yang lebih cepat dan aman untuk saling bertukar data, untuk terciptanya jaringan yang cepat dan aman maka diusulan perancangan Virtual Private Network (VPN) dengan Metode Point to Point Tunnel Protocol (PPTP) menggunakan Mikrotik. Adapun alat yang digunakan yaitu Mikrotik CHR. Dalam pengaplikasiannya Mikrotik CHR akan di jadikan server yang menghubungkan antara kantor pusat dengan cabang dimana Mikrotik yang ada di kantor pusat dan kantor cabang akan terhubung dengan IP address yang di distribusikan oleh Mikrotik CHR sehingga jaringan tersebut akan terhubung seperti jaringan lokal. Hasil akhir dari konfigurasi ini, terbentuknya jaringan VPN menggunakan metode PPTP pengujian akhir ditutup dengan di lakukannya uji coba PING dari komputer client ke Mikrotik CHR menghasilkan kecepatan sangat stabil yang terlihat dari waktu respon server dengan komputer.

The development of the textile business has become increasingly widespread, so that in supporting effectiveness in its implementation it requires connections so that they are connected to each other between one place and other company branches, but in practice the company needs a faster and safer network to exchange data, to create a fast and secure network then it is proposed to design a Virtual Private Network (VPN) with the Point to Point Tunnel Protocol (PPTP) method using Mikrotik. The tool used is Mikrotik CHR. In its application, Mikrotik CHR will be used as a server that connects the central office with branches where the Mikrotik at the head office and branch offices will be connected to the IP addresses distributed by Mikrotik CHR so that the network will be connected like a local network. The end result of this configuration, the formation of a VPN network using the PPTP method, the final test was closed by carrying out a PING test from the client computer to Mikrotik CHR resulting in a very stable speed as seen from the server's response time with the computer.
Primer hallazgo de Ascaris lumbricoides en un individuo del Calcolítico inicial en la Península Ibérica
Authors: López-Gijón Ramón , Duras Salvatore , Sánchez Susí Rafael , González Recio María Isabel , Rubio Salvador Ángel , Botella López Miguel Cecilio , Cámara Serrano Juan Antonio 
Published: December 2024

La implementación de la agricultura y la ganadería en poblaciones neolíticas supuso un aumento exponencial de las parasitosis, a consecuencia de factores derivados de esta nueva estrategia socio-económica, como el hacinamiento, la explotación de la tierra y el contacto directo con animales domésticos y peridomésticos. Este trabajo presenta los resultados obtenidos en el estudio de sedimento procedente de un individuo fechado a finales del Neolítico, el cual fue localizado en el área de Los Pilares del yacimiento arqueológico del Polideportivo de Martos (Jaén, España). El análisis desarrollado mediante microscopía óptica ha evidenciado la presencia de Ascaris lumbricoides en la muestra pélvica. Este hallazgo supone la primera contribución de parásitos intestinales procedentes de restos esqueléticos neolíticos realizada en la península Ibérica, permitiendo individualizar la parasitosis y relacionar este hallazgo con las evidencias antropológicas.
Isotopologues Detection and Quantitative Analysis by Mid‐Infrared Dual‐Comb Laser Spectroscopy
Authors: Vodopyanov Konstantin L. 
Published: March 2020

AbstractIsotopologues are molecules that differ from the parent molecule only in their isotopic composition. For example, ordinary light water (H2O), semi‐heavy water (HDO), and heavy water (D2O) are isotopologues of the same molecule. They have the same chemical formula and bonding arrangement of atoms, but at least one atom has a different number of neutrons than the parent. Isotopologues that differ only by the location of an isotopically modified element are called isotopomers. For example, the15N isotope in the N2O molecule can be either next to the oxygen atom or second next to it; thus, N15NO and15NNO are isotopomers of the same molecule. Detecting isotopologues of different molecules is critical in such fields as astrobiology, biogeochemistry, personalized medicine, and forensics, with mass spectrometry being a major technique to distinguish between different isotopologues. In this article, I focus on a new technique for detection of isotopologues based on laser spectroscopy. The backbone of this technology is massively parallel spectroscopic probing in the mid‐infrared spectral region by a frequency comb – a broad spectrum composed of some million phase‐locked equidistant sharp spectral lines – produced by a subharmonic optical parametric oscillator (OPO). Through assessing their unique rotational‐vibrational absorption signatures, we are able to simultaneously detect numerous molecules and their isotopologues in a mixture of gases, in real time and with one part‐per‐billion detection capability.
Platinum‐Based Anticancer Drugs
Authors: Liu Yan‐Cheng , Miller Jessica J. 
Published: March 2020

Abstract
In this article, the new developments on the platinum‐based anticancer drugs mainly in the past decade were remarked and discussed. These include the new research progress and insights on the classical platinum drugs, such as cisplatin and oxaliplatin, as well as the recent research progress on those nonclassical platinum‐based drugs. Especially, we focused on the emerging studies on the polynuclear platinum complexes, platinum(IV) complexes, and the photodynamic therapy and nanocarrier systems of these new types of platinum complexes. We have tried to select the most representative ones to be emphasized so that the most significant research progress of the platinum drugs may be shown and reported. This will inspire more scientists to develop better and more promising platinum‐based drugs based on these research findings in the future.
Still–Gennari Olefination and its Applications in Organic Synthesis
Authors: Janicki Ignacy , Kiełbasiński Piotr 
Published: March 2020

AbstractThe Still–Gennari olefination is a widely applied modification of the Horner–Wadsworth–Emmons reaction, allowing access to Z‐olefins by carbonyl group transformation. Its synthetic utility is undoubtedly of great significance for organic chemistry, as can be illustrated by the number of citations of the original report by W. C. Still and C. Gennari which up to date has been cited over 1000 times. In 2008 Nobel prize winner Ei‐ichi Negishi indicated the Still–Gennari olefination as one of the crucial methods for tolefin synthesis, complementary to palladium‐catalyzed alkenylations. Surprisingly, so far there is no review concerning this popular and valuable transformation. Therefore, we aim to comprehensively systematize achievements in this field and to present the scope of applications of the Still–Gennari olefination along with recent examples in the total synthesis of biologically active compounds. Our review is intended to be of interest for the general chemical community as well as to be a helpful source of information for synthetic organic chemists.magnified image
Achieving Room‐Temperature Charge Density Wave in Transition Metal Dichalcogenide 1T‐VSe2
Authors: Feng Jiajia , Susilo Resta A. , Lin Bencheng , Deng Wen , Wang Yanju , Li Bin , Jiang Kai , Chen Zhiqiang , Xing Xiangzhuo , Shi Zhixiang , Wang Chunlei , Chen Bin 
Published: March 2020

AbstractCharge density wave (CDW) systems have been widely studied and proposed to be potential candidates for next‐generation electronic devices. However, the lack of room‐temperature CDW materials has limited the development of CDW‐based electronic devices, and thus finding a way to manipulate the CDW transitions and orders toward room temperature will be of importance. Room‐temperature and above CDW transition in 1T‐VSe2 is reported. The CDW transition is found to shift to ≈114 K at 0.7 GPa, and further compression enhances the transition temperature dramatically, reaching ≈358 K at 14.6 GPa. High‐pressure Raman spectroscopy measurement confirms that room‐temperature CDW order is achieved and persists up to 15 GPa. Such significant enhancement in CDW can be attributed to the pressure enhanced out‐of‐plane Fermi surface nesting and CDW gap in 1T‐VSe2. The observation of room‐ and high‐temperature CDW transition in 1T‐VSe2 under pressure provides an engineering approach to optimizing the CDW as needed in applications, which does not only open up a new platform for searching and controlling novel states of two‐dimensional materials, but also promotes a practical development of CDW‐related technology and devices.
Light Harvesting at Oblique Incidence Decoupled from Transmission in Organic Solar Cells Exhibiting 9.8% Efficiency and 50% Visible Light Transparency
Authors: Liu Quan , Gerling Luis G. , Bernal‐Texca Francisco , Toudert Johann , Li Tengfei , Zhan Xiaowei , Martorell Jordi 
Published: March 2020

AbstractFor many years, it has been recognized that potential organic photovoltaic cells must be integrated into elements requiring high transparency. In most of such elements, sunlight is likely to be incident at large angles. Here it is demonstrated that light transmission can be largely decoupled from harvesting by optically tailoring an infrared shifted nonfullerene acceptor based organic cell architecture. A 9.67% power conversion efficiency at 50° incidence is achieved together with an average visual transmission above 50% at normal incidence. The deconstruction of a 1D nanophotonic structure is implemented to conclude that just two λ/4 thick layers are essential to reach, for a wide incidence angle range, a higher than 50% efficiency increase relative to the standard configuration reference. In an outdoor measurement of vertically positioned 50% visible transparent cells, it is demonstrated that 9.80% of sunlight energy can be converted into electricity during the course of 1 day.