bluuebunny/crossref_metadata_2025_split huggingface dataset:
Satellite-derived products of solar and longwave irradiances used for snowpack modelling in mountainous terrain
Authors: Quéno Louis , Karbou Fatima , Vionnet Vincent , Dombrowski-Etchevers Ingrid 
Published: April 2020

Abstract. In mountainous terrain, the snowpack is strongly affected by incoming shortwave and longwave radiation. In this study, a thorough evaluation of the solar and longwave downwelling irradiance products (DSSF and DSLF) derived from the Meteosat Second Generation satellite was undertaken in the French Alps and the Pyrenees. The satellite-derived products were compared with forecast fields from the meteorological model AROME and with analysis fields from the SAFRAN system. A new satellite-derived product (DSLFnew) was developed by combining satellite observations and AROME forecasts. An evaluation against in situ measurements showed lower errors for DSSF than AROME and SAFRAN in terms of solar irradiances. For longwave irradiances, we were not able to select the best product due to contrasted results falling in the range of uncertainty of the sensors. Spatial comparisons of the different datasets over the Alpine and Pyrenean domains highlighted a better representation of the spatial variability of solar fluxes by DSSF and AROME than SAFRAN. We also showed that the altitudinal gradient of longwave irradiance is too strong for DSLFnew and too weak for SAFRAN. These datasets were then used as radiative forcing together with AROME near-surface forecasts to drive distributed snowpack simulations by the model Crocus in the French Alps and the Pyrenees. An evaluation against in situ snow depth measurements showed higher biases when using satellite-derived products, despite their quality. This effect is attributed to some error compensations in the atmospheric forcing and the snowpack model. However, satellite-derived irradiance products are judged beneficial for snowpack modelling in mountains, when the error compensations are solved.
Verschillend organiseren, verschillend functioneren?
Authors: Nooteboom Laura , Eilander Janna , van der Voet Joris , Kuipers Ben , Steijn Bram , Vermeiren Robert , Mulder Eva 
Published: April 2020

Verschillend organiseren, verschillend functioneren? De invloed van de organisatie van Jeugd- (en Gezins)teams op het teamfunctioneren
Objective: there are regional differences in the organization of local Youth Teams, that have been given a crucial role in delivering Youth Care since the transition of Youth Care in 2015. The aim of this article is to examine the influence of the organization of Youth Teams on several aspects of their functioning.Method: self-managing teams in Holland Rijnland and teams in The Hague that are led by a team manager are compared on several aspects of team functioning. This mixed-methods study is based on an online questionnaire among 237 professionals and interviews with 32 professionals. Quantitative data have been analyzed by conducting a t-test of group means, qualitative data by means of framework-analysis.Results: the organization of Youth Teams seems to influence certain aspects of the perceived team functioning. For example, professionals in the self-organizing teams Holland Rijnland experience more self-management and more informational elaboration. However, there are also similarities on several aspects. Professionals from both regions have similar expectations of leaders.Discussion: municipalities and Youth Care organizations should be aware of the influence of the organization of Youth Teams on team functioning. Future research must demonstrate which aspects of team functioning contribute to improved care for families.
Une veille collaborative au service des revues : l’exemple du réseau Mir@bel
Authors: Vazquez Anabel , Fotiadi Sophie 
Published: April 2020

Mir@bel est à la fois un site Web, un réservoir partagé d’informations sur les
revues et un réseau de plus de 120 professionnels de l’information de différents horizons
qui partagent un travail de veille sur les revues et supervisent la mise à jour des données.
Le site propose, pour chaque revue, une description bibliographique, des rebonds vers
l’environnement numérique de la revue et des accès aux différents types de contenus diffusés
(articles, sommaires, résumés). Il reprend de manière automatisée des informations provenant
de nombreuses sources, dont les principaux portails de revues francophones en sciences
humaines et sociales (Cairn.info, Érudit, OpenEdition Journals et Persée).
Pour fonctionner, ce réseau s’appuie sur des méthodes de travail collaboratives, un
outil de veille partagé par des bibliothécaires et des professionnels de l’édition, mais
également sur les différents processus mis en place pour faciliter un travail
participatif.
En dix ans de fonctionnement, le réseau a pu expérimenter de nombreuses voies dans
cette veille collaborative, que ce soit pour la collecte, la mise à jour, les diffusions de
ces données ou la variété des partenariats, facilitant ainsi l’accès aux revues.
El hashtag contestatario: cuando los hashtags tienen efectos políticos
Authors: Zeifer Barbara 
Published: April 2020

El hashtag como elemento discursivo ha sido definido frecuentemente como una etiqueta que identifica el tema de un tuit (#decoración), o una indicación sobre cómo debe ser interpretado (#sorrynotsorry). Sin embargo, cada vez se hacen más frecuentes los hashtags que expresan reclamos y demandas sociales, que dan nombre a nuevos movimientos y colectivos, y que se encuentran inscriptos en las pancartas, banderas y carteles de las manifestaciones populares. Este artículo se propone estudiar en detalle este subtipo de hashtag, que denominaremos “hashtag contestatario”, a partir del análisis de tres casos contemporáneos: #BlackLivesMatter, #JeSuisCharlie y #NiUnaMenos. Los compararemos a partir de elementos tanto de la teoría política y social como del análisis del discurso, y procuraremos concluir con una definición de los hashtag contestatarios.
Nutritional profile of women assisted by the program of Family Health Strategy in Maranhão State, Brazil
Authors: Vieira Patricia Dore , Frota Maria Tereza Borges Araújo , Rocha Elida Mara Braga , Szarfarc Sophia Cornbluth , Bezerra Italla Maria Pinheiro , Nascimento Viviane Gabriela Pinheiro , Leone Claudio , Abreu Luiz Carlos de 
Published: April 2020

Introduction: Inadequate diet, whether due to excess or insufficient calories and nutrients, results in health risk situations as well as inadequate nutritional profile. The presence of nutritional deficiencies is more visible in women and, therefore, is more likely to reflect the risks of such deficiencies. Knowing the profile of the nutritional status of the female population of Maranhão, Brazil, which provide evidence of the nutritional status of their families, may support the creation of specific actions to combat eating problems and, consequently, improve their health.
Objective: To evaluate the nutritional profile and its relationship with social determinants in a population of women attended by the program of Family Health Strategy in Maranhão.
Methods: Cross-sectional study with 989 women aged 15 to 49 years, carried out during July to September 2010. Socioeconomic data were collected through a questionnaire, in addition it was applied of the Brazilian Food Insecurity Scale to know the level of food insecurity. Body mass index (BMI) and hip and waist circumference measurements were obtained to verify the nutritional profile. The variables were analyzed for frequencies, distribution and central tendency. Bivariate analysis was performed as to the associations between socioeconomic variables and BMI. The Spearman correlation coefficient was used between the food safety score and the BMI, adopting a significance level of 5%. Multivariate linear regression analysis was performed.
Results: It was found a relationship between the BMI classification with some social determinants such as age, family income and food insecurity. There is a high prevalence of women at nutritional risk, especially for overweight and obesity, as well as the presence of thinness and short stature.
Conclusion: Socioeconomic factors have a significant association with women's Body Mass Index indicating that there is an important relationship between age-matched maternal Body Mass Index and food insecurity.
Genetic modifiers of respiratory function in Duchenne muscular dystrophy
Authors: Bello Luca , D’Angelo Grazia , Villa Matteo , Fusto Aurora , Vianello Sara , Merlo Beatrice , Sabbatini Daniele , Barp Andrea , Gandossini Sandra , Magri Francesca , Comi Giacomo P. , Pedemonte Marina , Tacchetti Paola , Lanzillotta Valentina , Trucco Federica , D’Amico Adele , Bertini Enrico , Astrea Guja , Politano Luisa , Masson Riccardo , Baranello Giovanni , Albamonte Emilio , De Mattia Elisa , Rao Fabrizio , Sansone Valeria A. , Previtali Stefano , Messina Sonia , Vita Gian Luca , Berardinelli Angela , Mongini Tiziana , Pini Antonella , Pane Marika , Mercuri Eugenio , Vianello Andrea , Bruno Claudio , Hoffman Eric P. , Morgenroth Lauren , Gordish‐Dressman Heather , McDonald Craig M. ,   CINRG‐DNHS Investigators, Pegoraro Elena 
Published: April 2020

AbstractObjectiveRespiratory insufficiency is a major complication of Duchenne muscular dystrophy (DMD). Its progression shows considerable interindividual variability, which has been less thoroughly characterized and understood than in skeletal muscle. We collected pulmonary function testing (PFT) data from a large retrospective cohort followed at Centers collaborating in the Italian DMD Network. Furthermore, we analyzed PFT associations with different DMD mutation types, and with genetic variants in SPP1, LTBP4, CD40, and ACTN3, known to modify skeletal muscle weakness in DMD. Genetic association findings were independently validated in the Cooperative International Neuromuscular Research Group Duchenne Natural History Study (CINRG‐DNHS).Methods and ResultsGeneralized estimating equation analysis of 1852 PFTs from 327 Italian DMD patients, over an average follow‐up time of 4.5 years, estimated that forced vital capacity (FVC) declined yearly by −4.2%, forced expiratory volume in 1 sec by −5.0%, and peak expiratory flow (PEF) by −2.9%. Glucocorticoid (GC) treatment was associated with higher values of all PFT measures (approximately + 15% across disease stages). Mutations situated 3’ of DMD intron 44, thus predicted to alter the expression of short dystrophin isoforms, were associated with lower (approximately −6%) PFT values, a finding independently validated in the CINRG‐DNHS. Deletions amenable to skipping of exon 51 and 53 were independently associated with worse PFT outcomes. A meta‐analysis of the two cohorts identified detrimental effects of SPP1 rs28357094 and CD40 rs1883832 minor alleles on both FVC and PEF.InterpretationThese findings support GC efficacy in delaying respiratory insufficiency, and will be useful for the design and interpretation of clinical trials focused on respiratory endpoints in DMD.
Sandwich‐Structured Fe‐Ni2P/MoSx/NF Bifunctional Electrocatalyst for Overall Water Splitting
Authors: Zhang Xinglin , Liang Chen , Qu Xinyu , Ren Yanfang , Yin Jiajia , Wang Wenjun , Yang Mengsu , Huang Wei , Dong Xiaochen 
Published: April 2020

AbstractExploring cost‐efficient, high‐active bifunctional electrochemical catalysts with long‐term stability are significant for green economy. Herein, a noble‐metal‐free sandwich‐structured catalyst, prepared with facile hydrothermal method and phosphorization process, in which the amorphous MoSx serves as an intermediate layer between the Fe‐doped Ni2P and Ni foam substrate (Fe‐Ni2P/MoSx/NF) is reported. The obtained free‐standing catalyst performs an enhanced electrochemical activity compared with Fe‐Ni2P/NF and MoSx/NF. The Fe‐Ni2P/MoSx/NF catalyst only requires overpotentials of 246 mV to achieve 10 mA cm−2 and 277 mV to reach 50 mA cm−2 for oxygen evolution reaction process with a low Tafel slope of 59.7 mV dec−1 in alkaline solution. Meanwhile, an overpotential of 112 mV is demanded to reach 10 mA cm−2 for hydrogen evolution reaction. When the Fe‐Ni2P/MoSx/NF is used as two electrodes for overall water splitting, it requires 1.61 V to attain 10 mA cm−2 with prominent durability. This approach provides a versatile strategy to construct excellent bifunctional catalysts for effective water electrolysis.
Development and Validation of the Pediatric Physician Interpersonal Communication Skills Assessment of Emergency Physicians by Pediatric Patients and Their Caregivers
Authors: Hsu Deborah C. , Kumar Shelley , Russell Eric A. , Soto‐Ruiz Karina , Leaming‐Van Zandt Katherine J. 
Published: April 2020

AbstractObjectiveThe objective was to develop and validate an evaluation tool containing scaled items with behaviorally descriptive responses for pediatric patients and their caregivers (PCs) to evaluate and provide anonymous constructive feedback regarding interpersonal communication skills of pediatric emergency department (ED) physicians.MethodsA multistep validity‐driven approach consisting of literature review, structured input by subject matter experts, and end‐user focus group reviews was conducted to develop the Pediatric Physician Interpersonal Communication Skills Assessment (P‐PICSA) tool. Study subjects were enrolled prospectively (2011–2015). Psychometric analysis included exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and item response analysis. Cronbach’s alpha coefficient to determine internal consistency of subscale items, Pearson's correlation coefficient to estimate interscale correlations, and Spearman rank correlation coefficient to assess correlations between physician scores and ED factors that influence PC evaluations were calculated.ResultsFirst‐order EFA of 389 evaluations for 98 physicians yielded a two‐factor model: 1) physician engagement of PCs (six items) and 2) physician delivery of information to PCs (seven items). An additional 3,089 evaluations for 128 physicians were collected to test factor structure and scale quality. CFA was conducted on calibration (n = 1,222) and validation (n = 1,190) samples. A two‐factor structure was confirmed with satisfactory fit for both samples. Cronbach's alpha was 0.81 for factor 1 and 0.87 for factor 2. Physicians received lower scores if PCs perceived nonrespectful behavior from nonphysician staff or long ED lengths of stay, completed the Spanish version of the P‐PICSA, or were admitted to the hospital.ConclusionThe P‐PICSA is a reliable and valid tool for pediatric PCs to evaluate pediatric ED physicians’ interpersonal and communication skills. Compared to Likert‐type rating scales, the P‐PICSA’s behaviorally descriptive response items may provide ED physicians with more descriptive feedback and direction for skills improvement.
Maternal marital status predicts self‐reported stress among pregnant women following hurricane Florence
Authors: Howells Michaela E , Dancause Kelsey , Pond Richard , Rivera Latisha , Simmons Delthea , Alston Brionna D. 
Published: April 2020

AbstractObjectivesThe effects of stress caused by natural disasters may be more pronounced in individuals with preexisting disadvantages. The degree of hardship and psychological distress associated with Hurricane Florence was assessed in 83 pregnant women. This research helps identify unmarried pregnant women as a group particularly at risk of distress following a natural disaster.MethodsWe assessed hardship associated with the hurricane using a questionnaire modeled on previous studies of stress due to natural disasters. We assessed distress using the Impact of Event Scale‐Revised. We assessed social support and household food security using validated questionnaires. We used hierarchical linear regression to test predictors of distress marital status. Finally, we analyzed interactions between marital status and hardship, social support, and food security to examine whether these variables explained differences in distress among married and unmarried women.ResultsResults indicated that unmarried women may be at higher risk of distress following natural disasters. Unmarried women were younger, had lower food security and education levels. We found no differences between experiences of hurricane‐related hardship based on marital status. However, unmarried women were likely to have higher levels of distress following the hurricane. Hardship was a significant predictor of distress, but food security and social support were not significant predictors.ConclusionsThis study identifies unmarried pregnant women as a high risk/vulnerable group that may need additional support during emergencies. Taken together, this study further assesses how socially disadvantaged members of society may be unequally impacted by natural disasters.
Randomized Clinical Trial ofFirst‐LineGenome Sequencing in Pediatric White Matter Disorders
Authors: Vanderver Adeline , Bernard Geneviève , Helman Guy , Sherbini Omar , Boeck Ryan , Cohn Jeffrey , Collins Abigail , Demarest Scott , Dobbins Katherine , Emrick Lisa , Fraser Jamie L. , Masser‐Frye Diane , Hayward Jean , Karmarkar Swati , Keller Stephanie , Mirrop Samuel , Mitchell Wendy , Pathak Sheel , Sherr Elliott , van Haren Keith , Waters Erica , Wilson Jenny L. , Zhorne Leah , Schiffmann Raphael , van der Knaap Marjo S. , Pizzino Amy , Dubbs Holly , Shults Justine , Simons Cas , Taft Ryan J. ,   LeukoSEQ Workgroup
Published: April 2020

ObjectiveGenome sequencing (GS) is promising for unsolved leukodystrophies, but its efficacy has not been prospectively studied.MethodsA prospective time‐delayed crossover design trial of GS to assess the efficacy of GS as a first‐line diagnostic tool for genetic white matter disorders took place between December 1, 2015 and September 27, 2017. Patients were randomized to receive GS immediately with concurrent standard of care (SoC) testing, or to receive SoC testing for 4 months followed by GS.ResultsThirty‐four individuals were assessed at interim review. The genetic origin of 2 patient's leukoencephalopathy was resolved before randomization. Nine patients were stratified to the immediate intervention group and 23 patients to the delayed‐GS arm. The efficacy of GS was significant relative to SoC in the immediate (5/9 [56%] vs 0/9 [0%]; Wild–Seber,p< 0.005) and delayed (control) arms (14/23 [61%] vs 5/23 [22%]; Wild–Seber,p< 0.005). The time to diagnosis was significantly shorter in the immediate‐GS group (log‐rank test,p= 0.04). The overall diagnostic efficacy of combined GS and SoC approaches was 26 of 34 (76.5%, 95% confidence interval = 58.8–89.3%) in <4 months, greater than historical norms of <50% over 5 years. Owing to loss of clinical equipoise, the trial design was altered to a single‐arm observational study.InterpretationIn this study, first‐line GS provided earlier and greater diagnostic efficacy in white matter disorders. We provide an evidence‐based diagnostic testing algorithm to enable appropriate clinical GS utilization in this population.ANN NEUROL 2020;88:264–273.
Enantioselective Acetalization by Dynamic Kinetic Resolution for the Synthesis of γ‐Alkoxybutenolides by Thiourea/Quaternary Ammonium Salt Catalysts: Application to Strigolactones
Authors: Yasui Motohiro , Yamada Ayano , Tsukano Chihiro , Hamza Andrea , Pápai Imre , Takemoto Yoshiji 
Published: April 2020

AbstractAlthough acetalization is a fundamental transformation in organic synthesis, intermolecular asymmetric acetalization remains an unsolved problem. In this study, a thiourea‐ammonium hybrid catalyst was shown to promote the O‐alkylation of enols with a racemic γ‐chlorobutenolide through dynamic kinetic resolution to give chiral acetals with good enantioselectivity. The catalyst simultaneously activates both the nucleophile and electrophile in a multifunctional manner. This method was applied to the asymmetric synthesis of several strigolactones. DFT calculations suggest that hydrogen‐bonding interactions between the chlorine atom of the γ‐chlorobutenolide and the tosylamide hydrogen atom of the catalyst, as well as other types of noncovalent catalyst–substrate interactions, are crucial for achieving high stereoselectivity.
Unifying the Aminohexopyranose‐ and Peptidyl‐Nucleoside Antibiotics: Implications for Antibiotic Design
Authors: Serrano Catherine M. , Kanna Reddy Hariprasada Reddy , Eiler Daniel , Koch Michael , Tresco Ben I. C. , Barrows Louis R. , VanderLinden Ryan T. , Testa Charles A. , Sebahar Paul R. , Looper Ryan E. 
Published: April 2020

AbstractIn search of new anti‐tuberculars compatible with anti‐retroviral therapy we re‐identified amicetin as a lead compound. Amicetin's binding to the 70S ribosomal subunit of Thermus thermophilus (Tth) has been unambiguously determined by crystallography and reveals it to occupy the peptidyl transferase center P‐site of the ribosome. The amicetin binding site overlaps significantly with that of the well‐known protein synthesis inhibitor balsticidin S. Amicetin, however, is the first compound structurally characterized to bind to the P‐site with demonstrated selectivity for the inhibition of prokaryotic translation. The natural product‐ribosome structure enabled the synthesis of simplified analogues that retained both potency and selectivity for the inhibition of prokaryotic translation.
Zwei Diterpensynthasen aus Chryseobacterium: Chryseodien‐Synthase und Wanjudien‐Synthase
Authors: Lauterbach Lukas , Goldfuss Bernd , Dickschat Jeroen S. 
Published: April 2020

AbstractZwei bakterielle Diterpensynthasen (DTS) aus Chryseobacterium wurden charakterisiert. Das erste Enzym ergab die neue Verbindung Chryseodien, die nahe mit den Fusicoccan‐Diterpenen aus Pilzen verwandt ist, allerdings ist ihr experimentell und computerchemisch studierter Cyclisierungsmechanismus fundamental unterschiedlich zum Mechanismus der Fusicoccadien‐Synthase. Das zweite Enzym produzierte Wanjudien, einen Diterpenkohlenwasserstoff mit neuem Skelett, neben Spuren des Enantiomers von Bonnadien, das jüngst in Allokutzneria albata entdeckt wurde.
Influence of solvent and nanoparticles on the morphology and gas separation properties of copolyimide membranes
Authors: Maghami Saeid , Sadeghi Morteza , Khoshkam Milad , Chenar Mahdi Pourafshari 
Published: April 2020

AbstractIn this study, the effect of solvent type and nanoparticles of silica and zeolite 4A on the gas separation properties of polyimide (PI) membranes were investigated. Gas separation of the membranes based on pure solvents of dimethylformamide (DMF),n‐methyl‐2‐pirrolidone (NMP), dimethylacetamide (DMAc), and dimethylsulfoxide (DMSO) were studied. The prepared PI membranes using DMAc and DMSO showed the highest selectivity and permeability, respectively. In this regard, the influence of their mixing on transport properties of the PI was evaluated. The prepared membrane using the mixture of DMSO/DMAc with the volume ratio of 1:3 showed the best gas separation performance in comparison to the Robeson's upper bound. Incorporation of 20 wt% of silica and zeolite 4A nanoparticles into the PI membrane indicated that the selectivity of CO2/CH4increased from 39.4 to 57.6 and 68.5, respectively. Besides, gas transport properties of the PI‐based mixed matrix membranes were satisfactory predicted by modified Maxwell model. Furthermore, characteristic parameters of the encapsulated particles by interfacial layer were determined.