bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hamiltonians Generated by Parseval Frames
Authors: Bagarello F. , Kużel S. 
Published: December 2020

AbstractIt is known that self-adjoint Hamiltonians with purely discrete eigenvalues can be written as (infinite) linear combination of mutually orthogonal projectors with eigenvalues as coefficients of the expansion. The projectors are defined by the eigenvectors of the Hamiltonians. In some recent papers, this expansion has been extended to the case in which these eigenvectors form a Riesz basis or, more recently, a ${\mathcal{D}}$
D
-quasi basis (Bagarello and Bellomonte in J. Phys. A 50:145203, 2017, Bagarello et al. in J. Math. Phys. 59:033506, 2018), rather than an orthonormal basis. Here we discuss what can be done when these sets are replaced by Parseval frames. This interest is motivated by physical reasons, and in particular by the fact that the mathematical Hilbert space where the physical system is originally defined, contains sometimes also states which cannot really be occupied by the physical system itself. In particular, we show what changes in the spectrum of the observables, when going from orthonormal bases to Parseval frames. In this perspective we propose the notion of $E$
E
-connection for observables. Several examples are discussed.
Method comparison of HPLC-ninhydrin-photometry and UHPLC-PITC-tandem mass spectrometry for serum amino acid analyses in patients with complex congenital heart disease and controls
Authors: Michel Miriam , Salvador Christina , Wiedemair Verena , Adam Mark Gordian , Laser Kai Thorsten , Dubowy Karl-Otto , Entenmann Andreas , Karall Daniela , Geiger Ralf , Zlamy Manuela , Scholl-Bürgi Sabine 
Published: December 2020

AbstractIntroductionMetabolomics studies are not routine when quantifying amino acids (AA) in congenital heart disease (CHD).ObjectivesComparative analysis of 24 AA in serum by traditional high-performance liquid chromatography (HPLC) based on ion exchange and ninhydrin derivatisation followed by photometry (PM) with ultra-high-performance liquid chromatography and phenylisothiocyanate derivatisation followed by tandem mass spectrometry (TMS); interpretation of findings in CHD patients and controls.MethodsPM: Sample analysis as above (total run time, ~ 119 min).TMS: Sample analysis by AbsoluteIDQ® p180 kit assay (BIOCRATES Life Sciences AG, Innsbruck, Austria), which employs PITC derivatisation; separation of analytes on a Waters Acquity UHPLC BEH18 C18 reversed-phase column, using water and acetonitrile with 0.1% formic acid as the mobile phases; and quantification on a Triple-Stage Quadrupole tandem mass spectrometer (Thermo Fisher Scientific, Waltham, MA) with electrospray ionisation in the presence of internal standards (total run time, ~ 8 min). Calculation of coefficients of variation (CV) (for precision), intra- and interday accuracies, limits of detection (LOD), limits of quantification (LOQ), and mean concentrations.ResultsBoth methods yielded acceptable results with regard to precision (CV < 10%PM, < 20%TMS), accuracies (< 10%PM, < 34%TMS), LOD, and LOQ. For both Fontan patients and controls AA concentrations differed significantly between methods, but patterns yielded overall were parallel.ConclusionSerum AA concentrations differ with analytical methods but both methods are suitable for AA pattern recognition.TMS is a time-saving alternative to traditionalPMunder physiological conditions as well as in patients with CHD.Trial registration numberClinicalTrials.gov Identifier NCT03886935, date of registration March 27th, 2019 (retrospectively registered).
Adapted single-cell consensus clustering (adaSC3)
Authors: Fuetterer Cornelia , Augustin Thomas , Fuchs Christiane 
Published: December 2020

AbstractThe analysis of single-cell RNA sequencing data is of great importance in health research. It challenges data scientists, but has enormous potential in the context of personalized medicine. The clustering of single cells aims to detect different subgroups of cell populations within a patient in a data-driven manner. Some comparison studies denote single-cell consensus clustering (SC3), proposed by Kiselev et al. (Nat Methods 14(5):483–486, 2017), as the best method for classifying single-cell RNA sequencing data. SC3 includes Laplacian eigenmaps and a principal component analysis (PCA). Our proposal of unsupervised adapted single-cell consensus clustering (adaSC3) suggests to replace the linear PCA by diffusion maps, a non-linear method that takes the transition of single cells into account. We investigate the performance of adaSC3 in terms of accuracy on the data sets of the original source of SC3 as well as in a simulation study. A comparison of adaSC3 with SC3 as well as with related algorithms based on further alternative dimension reduction techniques shows a quite convincing behavior of adaSC3.
The Nematodes Thelazia gulosa Railiet and Henry, 1910 and Thelazia skrjabini Erschov, 1928 as a Cause of Blindness in European Bison (Bison bonasus) in Poland
Authors: Demiaszkiewicz Aleksander W. , Moskwa Bożena , Gralak Aneta , Laskowski Zdzisław , Myczka Anna W. , Kołodziej-Sobocińska Marta , Kaczor Stanisław , Plis-Kuprianowicz Elwira , Krzysiak Michał , Filip-Hutsch Katarzyna 
Published: December 2020

Abstract
Purpose
The nematodes of the genus Thelazia are the cause of eye diseases of wild and domestic ruminants throughout the world. The aim of the study was to describe clinical cases of thelasiosis in European bison (Bison bonasus) in Poland, and provide morphometrical features of Thelazia gulosa Railiet and Henry, 1910 and Thelazia skrjabini Erschov, 1928 regarded as potentially useful for species differentiation

Methods
The conjunctival sacs, tear ducts, the surface of the cornea and nicitating membrane collected from bison were rinsed with saline solution. Any nematodes isolated from the sediment were subjected to morphometric analysis.

Results
Thirteen of the 16 examined European bison were infected with Thelazia nematodes, belonging to the species T. gulosa and T. skrjabini. The intensity of infection ranged from one to six (mean intensity 5), and four to 29 (mean intensity 14) nematodes T. skrjabini and T. gulosa respectively. Congestion of conjunctival sac, keratitis and corneal opacity, corneal ulceration and perforation as well as purulent eyeball inflammation were observed in infected animals.

Conclusions
Thelazia gulosa and T. skrjabini can be identified by morphometrical features. As thelasiosis might be a serious threat for protected population of European bison, further studies are needed of the epidemiology and pathology of this emerging parasitosis in Poland.
Genotypes of Giardia duodenalis in Household Dogs and Cats from Poland
Authors: Piekara-Stępińska Agnieszka , Piekarska Jolanta , Gorczykowski Michał , Bania Jacek 
Published: December 2020

Abstract
Background
Giardia duodenalis is a widespread protozoan parasite affecting humans and many species of animals, including dogs and cats. Due to its zoonotic potential, it is important to know the frequency of this parasite in companion animals. The aim of this study was to determine current epidemiological status of G. duodenalis in household dogs and cats.

Methods
In this study, 293 fecal samples from pet dogs and cats were collected from January 2017 to July 2019 and tested for G. duodenalis by PCR (using β-giardin gene). The animals were divided into groups depending on their age, breed and fecal consistency.

Results
The examination allowed for detection of G. duodenalis in 6.0% of canine and 3.9% of feline fecal samples. The highest frequency was revealed in young (under one-year old) dogs. Sequencing confirmed the presence of assemblages C and D in dogs and A and F in cats.

Conclusion
The study showed current frequency of G. duodenalis in dogs and cats and also revealed the occurrence of host-specific assemblages as well as zoonotic assemblage A.
Numerical Investigation on the Ultimate Strength of Box Beams with Impact Damage
Authors: Xu Wei , Soares C. Guedes 
Published: December 2020

AbstractThe objective of this paper is to study the residual ultimate strength of box beams with impact-induced damage, as a model of what may occur in ship hulls. The bottom and side plates of ship hulls can suffer denting or fracture damage due to grounding, collision and other contacts during the ship’s service life and these impact-induced damages could result in considerable strength degradation. Box beams are firstly subjected to impact loading and then four-point bending loading is imposed on the damaged structures to assess the residual strength using ANSYS/LS_DYNA. The ultimate moment and collapse modes are discussed considering the effect of impact location. The impact-induced deformation is introduced in the four-point bending simulation, and the impact-induced stress is included or not to determine the effect of residual stress and distortion after impact. It is shown that impact location has significant influence on the residual ultimate bending moment of the damaged box beam providing that the impact energy is kept constant. The collapse modes also change when the impactor strikes on different locations. Damaged hard corner and inclined neutral axes might explain the reduction of ultimate strength and diverse collapse modes. The residual stress in the box beam after impact may increase or decrease the ultimate strength depending on impact location.
A Global Decline in Adolescents’ Subjective Well-Being: a Comparative Study Exploring Patterns of Change in the Life Satisfaction of 15-Year-Old Students in 46 Countries
Authors: Marquez Jose , Long Emily 
Published: December 2020

AbstractThere is a growing body of research that demonstrates declines in subjective well-being and increases in mental health problems among children and young people in recent decades. However, there is little comparative research examining changes in adolescents’ life satisfaction (LS) across a large number of countries, and critically, how this differs across sociodemographic groups. This study addresses this question by investigating changes in the LS of 15-year-old students between 2015 and 2018, with particular attention given to differences by gender, socio-economic status, immigrant background and urbanity. Data for this study come from the Programme for International Student Assessment (PISA). Due to the skewed nature of LS scale variables, the current study includes both mean levels of LS in a 0 to 10 scale, and the proportion of students reporting low LS (5 points or less). Linear regression models were used. Results demonstrate a global decline in mean levels of LS in 39 out of the 46 countries. In most countries, mean LS declined more among girls than among boys. Mean LS declined more, and the proportion of students reporting low LS increased more, among non-immigrant students and those of higher SES in the majority of countries. Findings regarding rural or urban communities were mixed. We advise that heterogeneity across all sociodemographic groups needs to be accounted for in public policy efforts to increase LS among young people.
Monte Carlo cubature construction
Authors: Hayakawa Satoshi 
Published: December 2020

AbstractIn numerical integration, cubature methods are effective, especially when the integrands can be well-approximated by known test functions, such as polynomials. However, the construction of cubature formulas has not generally been known, and existing examples only represent the particular domains of integrands, such as hypercubes and spheres. In this study, we show that cubature formulas can be constructed for probability measures provided that we have an i.i.d. sampler from the measure and the mean values of given test functions. Moreover, the proposed method also works as a means of data compression, even if sufficient prior information of the measure is not available.
Impact of Temperature and Time Interval Prior to Immature Testicular-Tissue Organotypic Culture on Cellular Niche
Authors: Salian Sujith Raj , Pandya Riddhi Kirit , Laxminarayana Sindhura Lakshmi Koulmane , Krishnamurthy Hanumantappa , Cheredath Aswathi , Tholeti Prathima , Uppangala Shubhashree , Kalthur Guruprasad , Majumdar Subeer , Schlatt Stefan , Adiga Satish Kumar 
Published: December 2020

AbstractCryopreservation of immature-testicular-tissue (ITT) prior to gonadotoxic treatment, while experimental, is the only recommended option for fertility preservation in prepubertal boys. The handling and manipulation of ITT before cryopreservation could influence the functionality of cells during fertility restoration, which this study explored by evaluating cellular niche and quality of mouse ITT subjected to various temperatures and time durations in vitro. ITT from 6-day-old mice were handled at ultraprofound-hypothermic, profound-hypothermic, and mild-warm-ischemic temperatures for varying time periods prior to 14-day organotypic culture. Viability, functionality, synaptonemal complex and chromatin remodeling markers were assessed. Results have shown that cell viability, testosterone level, and in vitro proliferation ability did not change when ITT were held at ultraprofound-hypothermic-temperature up to 24 h, whereas cell viability was significantly reduced (P < 0.01), when held at profound-hypothermic-temperature for 24 h before culture. Further, cell viability and testosterone levels in cultured cells from profound-hypothermic group were comparable to corresponding ultraprofound-hypothermic group but with moderate reduction in postmeiotic cells (P < 0.01). In conclusion, holding ITT at ultraprofound-hypothermic-temperature is most suitable for organotypic culture, whereas short-term exposure at profound-hypothermic-temperature may compromise postmeiotic germ cell yield post in vitro culture. This data, albeit in mouse model, will have immense value in human prepubertal fertility restoration research.
CHURCH-STATE SYMPHONIA: ITS HISTORICAL DEVELOPMENT AND ITS APPLICATIONS BY THE RUSSIAN ORTHODOX CHURCH
Authors: Antonov Mikhail 
Published: December 2020

AbstractThis article analyzes the origins of the concept of symphonia, its historical development, and its utilization by the Russian Orthodox Church as a normative ideal for church-state relations. In various historical contexts, this concept has referred to different normative requirements; it relied on different paradigms in Byzantium and in medieval Russia and it acquired new meanings in Imperial Russia. The reinterpretations of this concept by the Russian Orthodox Church in order to legitimize its position in the political life of contemporary Russia take this concept far from its original meaning. Using methods from the history of concepts of, among others, Reinhart Koselleck and Quentin Skinner, the author considers how the semantic transformations of symphonia in modern contexts by the Russian Orthodox Church lead to a hollowing of this concept. This conception is hardly reconcilable with the normative logic of the actual Russian political and legal systems.
Low doses of eriocitrin attenuate metabolic impairment of glucose and lipids in ongoing obesogenic diet in mice
Authors: Ferreira P. S. , Manthey J. A. , Nery M. S. , Spolidorio L. C. , Cesar T. B. 
Published: December 2020

AbstractEriocitrin is a citrus flavonoid with a high capacity to reduce the oxidative stress related to metabolic disorders and obesity. We assessed the effects of low doses of eriocitrin on the oxidative stress, inflammation, and metabolism of glucose and lipids of high-fat diet (HFD)-fed obese mice. Fifty male C57BL/6J mice were randomly assigned into five groups (n10). The mice were fed an HFD (45 % kcal from fat, i.e. lard) for 4 weeks for obesity induction. After this period, the mice continued receiving the same HFD, but supplemented with eriocitrin at 10, 25 or 100 mg/kg body weight (bw) for an additional 4 weeks. Control groups were fed with standard diet (10 % kcal of fat, i.e. soy oil) or with HFD without eriocitrin, for eight consecutive weeks. At the end of the study, mice supplemented with eriocitrin showed lower levels of blood serum glucose and blood and liver triacylglycerols (P< 0⋅05). There was also improved levels of insulin, HOMA-IR, total-cholesterol, resistin and lipid peroxidation in the supplemented mice. It was concluded that the 25 mg dose of eriocitrin improved all the parameters studied and had positive effects on oxidative stress, systemic inflammation and metabolism of lipids and glucose in general.
Tibetan medicine with respect to increased attention to the east in Russian society: The second half of the nineteenth century to early twentieth century
Authors: Suvorov Valeriy V. , Kiselev Anton R. , Fedonnikov Alexander S. 
Published: December 2020

AbstractGrowing interest to Tibetan medicine among the Russian scientific community and popularisation of its practices in the Russian Empire metropolitan areas in the second half of the nineteenth century to early twentieth century concurred with on-going changes in perception of the Orient by Russian society, establishment of its positive image, increased interest to the elements of oriental culture and practices within the framework of the Silver Age values, and the development of the natural science and experimental medicine, both of which caused an improvement in the healthcare system in Russia. At the turn of the twentieth century, Russian society manifested an ambivalent attitude towards Tibetan medicine. On the one hand, there was an increasing interest to theoretical foundations, a desire for scientific understanding, and spread of the Tibetan medicine practical component in the sociocultural environment of the metropolitan society, previously unfamiliar with oriental traditions and beliefs. On the other hand, an issue of the possibilities and principles of Tibetan medical treatment had opposed Western scientific medicine, which produced many discussions and critical reviews. The controversy was repeatedly caused by the negative attitude towards principal metropolitan specialist in Tibetan medicine – Peter Badmaev and distrust to his activities, as opposed to the medical skills of actual lamas. Despite the fact that it was virtually impossible to integrate Tibetan medicine into the Russian healthcare system, interest in it became a factor of attraction to the East and the oriental culture in Russian society at the turn of the twentieth century.
A mathematical model explores the contributions of bending and stretching forces to shoot gravitropism in Arabidopsis
Authors: Tsugawa Satoru , Sano Tomohiko G. , Shima Hiroyuki , Morita Miyo Terao , Demura Taku 
Published: December 2020

AbstractPlant shoot gravitropism is a complex phenomenon resulting from gravity sensing, curvature sensing (proprioception), the ability to uphold self-weight and growth. Although recent data analysis and modelling have revealed the detailed morphology of shoot bending, the relative contribution of bending force (derived from the gravi-proprioceptive response) and stretching force (derived from shoot axial growth) behind gravitropism remains poorly understood. To address this gap, we combined morphological data with a theoretical model to analyze shoot bending in wild-type and lazy1-like 1 mutant Arabidopsis thaliana. Using data from actual bending events, we searched for model parameters that minimized discrepancies between the data and mathematical model. The resulting model suggests that both the bending force and the stretching force differ significantly between the wild type and mutant. We discuss the implications of the mechanical forces associated with differential cell growth and present a plausible mechanical explanation of shoot gravitropism.
The Politics of Pandemic Othering: Putting COVID-19 in Global and Historical Context
Authors: Dionne Kim Yi , Turkmen Fulya Felicity 
Published: December 2020

AbstractAs COVID-19 began to spread around the world, so did reports of discrimination and violence against people from marginalized groups. We argue that in a global politics characterized by racialized inequality, pandemics such as COVID-19 exacerbate the marginalization of already oppressed groups. We review published research on previous pandemics to historicize pandemic othering and blame, and enumerate some of the consequences for politics, policy, and public health. Specifically, we draw on lessons from smallpox outbreaks, the third bubonic plague, the 1918 influenza pandemic, and more recent pandemics, such as HIV/AIDS, SARS, and Ebola. We also compile reports to document the discrimination and violence targeting marginalized groups early in the COVID-19 pandemic. This article lays bare the continuation of a long history of othering and blame during disease outbreaks and identifies needs for further inquiry to understand the persistence of these pandemic politics.
Brag-bar kinship system in synchronic and diachronic perspectives
Authors: Shuya Zhang , Jingming Fan 
Published: December 2020

AbstractThe Rgyalrong languages are a group of unwritten non-Tibetic languages spoken in north-western Sichuan Province, China. This paper provides an in-depth analysis of the Brag-bar (a dialect of Situ Rgyalrong) kinship terminology at the synchronic level, and then by using both internal reconstruction and comparative method, we attempt to explain the directionality of both formal and semantic changes in the Brag-bar terminology. Thus we demonstrate that the present kinship system of Brag-bar (Situ) originates from a system with Omaha skewing.
Role of patients’ organizations in Health Technology Assessment: a Habermasian system and lifeworld perspective
Authors: Milevska-Kostova Neda , Duddi Sita Ratna Devi , Cooper Richard J. 
Published: December 2020

Abstract
Patient and public involvement in Health Technology Assessment (HTA) is gaining increased interest among research and policy communities. Patients’ organizations represent an important link between individual patients and the health system. Social theories are increasingly being used to explain doctor–patient–system interactions, expanding understanding beyond the mere clinical perspective. In this sense, patient involvement in HTA can also be considered through the Habermas’s theory of communicative action. From a Habermasian perspective, HTA as part of the instrumental rationality contributes to an increased efficiency of resource use within the system; however, such rationalization threatens to colonize the lifeworld by making it “increasingly state administered with attenuated possibilities for communicative action as a result of the commercialization and rationalization in terms of immediate returns.” Using Habermasian system/lifeworld framework, this paper explores opportunities and obstacles to patient involvement in HTA, whereby trying to understand current and possible roles of patients’ organizations as a mediating force between HTA as a function of the system and the lifeworld represented by patients.