bluuebunny/crossref_metadata_2025_split huggingface dataset:
Applying HT-NGH Algorithm On A Shared Memory Architecture For Time Performance Improvement
Authors: abu-hashem muhannad 
Published: May 2020

Abstract
Background: Sequence comparison and alignment plays an important role in computational biology as they allow for rating the similarities between molecular sequences. Pair-wise alignment contributes significantly in calculating the similarity between sequences by constructing the optimal alignment. The Hash Table-N-Gram-Hirschberg (HT-NGH) algorithm, which is an extension to the Hashing-N-Gram-Hirschberg (HNGH) and N-Gram-Hirschberg (NGH) algorithms, represents a pair-wise alignment method that uses the capabilities of the hash table technique for the purpose of building the alignment. Due to the current technology, molecular databases have exponentially grown to highlight the needs for faster and efficient methods that can handle these amounts of data. On the other hand, the present technology provides a verity of high performance architectures and tools. Results: This paper presents a parallel shared memory algorithm for protein pair-wise alignment method, namely, the HT-NGH algorithm in order to enhance the time performance of sequences’ comparisons and alignments. The proposed parallel algorithm targets the transformation phase of the HT-NGH algorithm since it consumes about 10% of alignment’s executional time. Datasets are decomposed up to sequence level for a more efficient utilization of processing units (no idle processing unit). Conclusions: As a result, the proposed algorithm demonstrates a significant improvement in terms of time performance without sacrificing accuracy. The speed up pertaining to the parallel algorithm reaches 2.08, 2.88, and 3.87 when using 2, 3, and 4 cores, respectively. Furthermore, this algorithm gains high efficiency as it reaches 1.04, 0.96, and 0.97 when using 2, 3, and 4 cores, respectively.
Cardiac MRI utilizing late gadolinium enhancement (LGE) and T1 mapping in the detection of radiation induced heart disease
Authors: Ricco Anthony , Slade Alexander , Canada Justin , Grizzard John , Dana Franklin , Gharai Leila Rezai , Neiderer Keith , Vera Armando , Abbate Antonio , Weiss Elisabeth 
Published: May 2020

Abstract
Background and Purpose

Radiotherapy has been associated with late dose-dependent cardiovascular toxicity. In this cross-sectional pilot study, radiation dose distributions were correlated with areas of localized and diffuse myocardial fibrosis as measured by novel cardiac MRI (CMR) sequences including late gadolinium enhancement (LGE) and T1 mapping with the goal to identify early markers of myocardial damage.

Materials and Methods

Twenty-eight patients with chest tumors including lung, breast, esophagus, and lymphoma underwent CMR per study protocol on average 46.4 months (range 1.7-344.5) after radiotherapy. Patients without pretreatment cardiac history were included if the volume of heart receiving 5 Gy or more was at least 10% (V5Gy≥10%). The association of LGE with cardiac dosimetric factors, clinical factors (e.g., tumor type, smoking history, BMI), , and T1 values was analyzed.

Results

Cardiac maximum (Dmax) and mean dose (Dmean) equivalent to doses delivered in 2 Gy fractions (EQD2) were on average 50.9 Gy (range 6.2-108.0) and 8.2 Gy (range 1.0-35.7), respectively, compared to 60.8 Gy (40.8-108.0) and 6.8 Gy (1.8-21.8) among the 9 patients with LGE. Doses were not different between patients with and without LGE (p=0.16 and 0.56, respectively). The average T1 value of the left ventricle myocardium was 1009 ms (range 933-1117). No significant correlation was seen for heart Dmax and Dmean and T1 values (p=0.14 and 0.58, respectively). In addition, no significant association between clinical factors and the development of LGE was identified.

Conclusions

No relation between cardiac doses, the presence of LGE or T1 values was observed. Further study is needed to determine the benefit of CMR for detecting radiotherapy-related myocardial fibrosis.
Data Science in Economics
Authors: Nosratabadi Saeed , Mosavi Amir , Duan Puhong , Ghamisi Pedram , Filip Ferdinand 
Published: May 2020

Abstract
This paper provides the state of the art of data science in economics. Through a novel taxonomy of applications and methods advances in data science are investigated. The novel data science methods and applications are investigated in four individual classes of deep learning models, hybrid deep learning models, hybrid machine learning, and ensemble models. Application domains include a wide range of economics research, from stock market, marketing, E-commerce, to corporate banking, and cryptocurrency. Prisma method, a systematic literature review methodology is used to ensure the quality of the survey. The findings revealed that the trends are on the advancement of hybrid models. On the other hand, based on the accuracy metric it is also reported that the hybrid models outperform other learning algorithms. It is further expected that the trends would go toward the advancements of sophisticated hybrid deep learning models.
Comparative outcomes of lopinavir/ritonavir and hydroxychloroquine for the treatment of coronavirus disease 2019 with mild to moderate severity.
Authors: Lee Jeong Eun , Lee Soon Ok , Heo Jeonghun , Kim Dong Wan , Park Mi Ran , Son Hyunjin , Kim Dongkeun , Kim Kye-Hyung , Lee Shinwon , Lee Sun Hee 
Published: May 2020

Abstract
Background: Lopinavir/ritonavir and hydroxychloroquine are both being used to treat COVID-19, but their relative effectiveness is unknown. The purpose of this study was to compare the clinical outcomes of patients treated for COVID-19 with lopinavir/ritonavir (LPV/r) or hydroxychloroquine (HCQ).Methods: A retrospective cohort study was conducted at 2 hospitals in Busan, South Korea, that treated approximately 90% of COVID-19 patients hospitalized in Busan during the study period. All patients aged ≥15 years that were hospitalized with mild-or-moderate COVID-19 received LPV/r or HCQ as their initial treatment and were included in the analysis.Results: Among the 72 patients with mild-to-moderate disease severity on admission, 45 received LPV/r and 27 received HCQ as their initial therapy. A higher proportion of the LPV group had pneumonia on admission (LPV 49% vs. HCQ 15%), but there were no other significant differences in the demographic or clinical characteristics between groups.Switching therapy due to clinical failure was significantly more common in the HCQ group than in the LPV/r group (41% [11/27] and 2% [1/45], respectively, P=0.001). Disease progression was also significantly more common in the HCQ group than in the LPV/r group (44% [12/27] and 18% [8/45], respectively, P=0.030).Conclusions: LPV/r appears to be more effective than HCQ at preventing progression to severe disease in patients with COVID-19.
Application of 32Full Factorial Design and Desirability Function for Optimizing The Manufacturing Process for Directly Compressible Multi-Functional Co-Processed Excipient
Authors: Patel Jalpa , Mori Dhaval 
Published: May 2020

Background:Developing a new excipient and obtaining its market approval is an expensive, time-consuming and complex process. Compared to that, the co-processing of already approved excipients has emerged as a more attractive option for bringing better characteristic excipients to the market. The application of the Design of Experiments (DoE) approach for developing co-processed excipient can make the entire process cost-effective and rapid.Objective:The aim of the present investigation was to demonstrate the applicability of the DoE approach, especially 32 full factorial design, to develop a multi-functional co-processed excipient for the direct compression of model drug - cefixime trihydrate using spray drying technique.Methods:The preliminary studies proved the significant effect of atomization pressure (X1) and polymer ratio (microcrystalline cellulose: mannitol - X2) on critical product characteristics, so they were selected as independent variables. The angle of repose, Carr’s index, Hausner’s ratio, tensile strength and Kuno’s constant were selected as response variables.Result:The statistical analysis proved a significant effect of both independent variables on all response variables with a significant p-value < 0.05. The desirability function available in Design Expert 11® software was used to prepare and select the optimized batch. The prepared co-processed excipient had better compressibility than individual excipients and their physical mixture and was able to accommodate more than 40 percent drug without compromising the flow property and compressibility.Conclusion:The present investigation successfully proved the applicability of 32full factorial design as an effective tool for optimizing the spray drying process to prepare a multi-functional co-processed excipient.
Targeted Delivery of Colloidal Silver for MCF-7 Breast Cancer Treatment
Authors: Rajawat Shweta , Malik Manzar M. 
Published: May 2020

Background:Amongst various cancer diseases, breast cancer is frequently diagnosed malignancy in women. Existing treatments are inadequate, painful and toxic. New ways of treatments need to be explored.Methods:The present work proposes preparation and targeted delivery of a formulation, F-1, for MCF-7 breast cancer treatment. The formulation, colloidal silver (0.76 ppm), was prepared by electrolytic deposition technique and multi surface coatings. Black tea extract (2.25%v/v) was used as a capping agent to tune the morphology of silver nanoparticle and potato extract (6.25%v/v) as a functionalizing agent for targeting MCF-7 breast cancer site.Results:Characterization results show highly pure spherical silver nanoparticles with an average particle size of 15nm. The shift of peaks in the FTIR spectra of formulation confirms the interaction between nanoparticles and extracts. The UV-visible peak was obtained at 525nm, a typical characteristic of silver nanoparticles.In-vivoanti-cancer study of formulation gave a moderate therapeutic effect in Non-Obese Diabetic Severe Combined Immune Deficiency (NOD-SCID) mice.Conclusion:It is observed that tumor volumes obtained in the case of Formulation-1 were moderately inhibited from days 5 to 9. However, one of the mice in the Formulation-1 group inhibited tumor volume to 1.52 cc similar to one of the mice of positive control group (Adriamycin 1.42cc).
La corrupción gubernamental y su percepción entre los universitarios tamaulipecos
Authors: Ramírez Sirgo Luis Eduardo , Casas Cárdenas Ernesto 
Published: May 2020

<span>En los últimos años ha sido común la difusión de hechos de corrupción en México, en los que están implicados servidores públicos de alto nivel indistintamente del partido político al que pertenezcan; los casos destacan tanto por la cantidad de recursos públicos sustraídos de las arcas gubernamentales, como por las redes de protección institucional de que han dispuesto, así como por la falta de sanción judicial. En este marco, la presente investigación tiene como objetivo conocer el fenómeno de la corrupción gubernamental en México, particularmente en el estado de Tamaulipas, de acuerdo con diferentes índices elaborados por instituciones públicas y privadas; asimismo, conocer la percepción de los universitarios tamaulipecos sobre este problema social</span>
Authors: Nasution Nurul Maidah , Prarikeslan Widya 
Published: May 2020

Tujuan penelitian adalah melihat sebaran suhu permukaan laut, konsentrasi klorofil-a, hubungan antara suhu permukaan laut dengan klorofil-a serta zona potensial penangkapan ikan bulan Juni, Juli dan Agustus berdasarkan data 3 tahun terakhir menggunakan citra terra modis. Metode yang digunakan adalah analisis overlay antara suhu permukaan laut, konsentrasi klorofil-a dengan melihat faktor kedalaman dan mempertimbangkan jalur penangkapan ikan. Hasil yang didapatkan suhu permukaan laut memiliki sebaran antara 27,10C – 32,20C, Umumnya suhu bulan Juni lebih tinggi dibandingkan bulan Juli dan Agustus mencapai 32,20C tahun 2018. Klorofil-a berkisar antara 0,1 – 6,2 mg/m3 dengan konsentrasi klorofil-a tertinggi mencapai terjadi pada bulan Juni. Analisis hubungan antara suhu permukaan laut dengan klorofil-a melalui regresi linear sederhana, ada pengaruh yang sangat kuat antara suhu permukaan laut dengan klorofil-a terlihat dari koefisien korelasi (R) 0,826, koefisien determinasi (R2) 0,683 yang artinya suhu permukaan laut di pantai Natal berpengaruh terhadap klorofil-a sebesar 68,3% selebihnya dipengaruhnya oleh faktor lain. Zona potensial penangkapan ikan (fishing ground) terjadi pada zona Ib hingga zona II DPPI.
Kata kunci: terra modis; spl; klorofil-a; ikan kembung; daerah penangkapan ikan
Aprendiendo en el "más acá": Entrevista realizada a Quimey Sol Ramos en el Bachillerato Popular Trans "Mocha Celis", el 25 de agosto de 2019
Authors: Raina Andrea 
Published: May 2020

Dialogar con Quimey Ramos es mínimamente una invitación a preguntarnos, a repensarnos, a emocionarnos, a debatir… a cuestionarlo todo.
Entrevistarla fue una experiencia transformadora en los términos que ha enseñado Alessandro Portelli: involucrando nuestra subjetividad como historiadores/as, aumentando nuestras responsabilidades en el oficio; pero también y sobre todo, desde lo primero y más simple que es nuestra humanidad. Cada una de las reflexiones que Quimey nos compartió caló un poco más hondo, llegando al hueso de cada una de las preguntas, pero para encontrarnos con mas inquietudes; como en un juego de Mamushkas interminable que nos topaba con sentidos más profundos cada vez. Con la capacidad de entrar en un laberinto pero saliendo cada vez con más claridad, afirmando aquellas certezas con la convicción que sólo las verdades vividas te dan.
Hablamos, de memorias, de verdades, de in-justicias, de historias, de derechos, de subversión, de educación, hablamos del "más allá" y el "más acá" de una sociedad que divide, hablamos de la necesidad de reconocernos, de sincerarnos y del cambio urgente que queremos
REVIEW OF ENERGY MINIMIZATION TECHNIQUES IN WIRELESS SENSORS NETWORK
Authors: Mubel Basantilal , Goyal Dr. Sachin , Agrawal Dr. Ratish 
Published: May 2020

The current decade of technology trends adopted the utilization of wireless sensors network. The wireless sensors network integrates with cloud based services and facilitate in every field of social engineering. The success story of sensors based network is utilization of energy. The sensor devices occupied tiny battery for energy. If the energy utilization is not maintained the life of network is expire. In this paper present the review of energy based protocol used in wireless sensor network. The maximum utilization of energy during the sensing of data of sensors node. Some authors used dual duty cycle for the sensing of sensor data and transmit data to sink node.
Respon Pertumbuhan, Produksi dan Kualitas Daun Duduk (Desmodium triquetrum (L.) D.C.) Terhadap Ketinggian Tempat Budidaya
Authors: Muslim Fauzi , Subositi Dyah 
Published: May 2020

Daun duduk (Desmodium triquetrum (L.) DC.) is a medicinal plant containing flavonoid compounds, saponins, polyphenols, and trigonelline. These plants are spread throughout Indonesia especially on Java, Madura, and Sumatra from lowland areas to highlands at an altitude of 5-1,500 m above sea level. Daun duduk has not been widely cultivated. The aim of this study was to determine effects of altitudes to growth, productivity, and quality of daun duduk. The research was carried out in the experimental garden of Medicinal Plant and Traditional Medicine Research and Development Center in January - September 2016. The experiment used a Randomized Block Design in four locations that has different altitudes such as 200, 450 and 1,200 m asl. The results showed that the altitude of location significantly affected the growth, production, and flavonoid contents of daun duduk. The optimal plant height (179.90 cm) was obtained from location at an altitude of 1,200 m above sea level. The highest number and dry weight of leaves were produced in location at an altitude of 200 m asl. While the levels of water soluble extract was 19.7337%, soluble extract levels of ethanol was 18.2837%, and total flavonoid content was 0.249% were obtained at 450 m asl.
Perbandingan Metode Seasonal Autoregressive Integrated Moving Average (SARIMA) dengan Support Vector Regression (SVR) dalam Memprediksi Jumlah Kunjungan Wisatawan Mancanegara ke Bali
Authors: Hendayanti Ni Putu Nanik , Nurhidayati Maulida 
Published: May 2020

Berbagai sumber pendapatan yang dapat dihasilkan dalam suatu daerah, salah satunya yaitu dalam sektor pariwisata. Seperti halnya sektor yang lain, sektor pariwisata juga memberikan banyak sumbangan bagi pembangunan ekonomi di suatu daerah maupun negara tujuan wisata. Indonesia memiliki banyak tujuan wisata daerah yang sudah terkenal hingga mancanegara salah satunya yaitu Pulau Bali. Bali merupakan daerah yang sudah memiliki kedudukan yang sejajar dengan daerah-daerah tujuan wisata lainnya yang ada di dunia. Sebagai suatu daerah yang sangat berpotensi dalam pengembangan wisata, maka pemerintah memberikan perhatian yang khusus dalam pengembangan pariwisata di Pulau Bali. Maka dari itu, perlu adanya peramalan jumlah kunjungan wisatawan mancanegara ke Bali yang nantinya bisa bermanfaat bagi pemerintah daerah maupun dinas pariwisata. Dalam hal ini, akan digunakan dua metode untuk meramalkan jumlah kunjungan wisatawan mancanegara ke Bali. Adapun metode yang digunakan yaitu Seasonal ARIMA dan Support Vector Regression (SVR). Hasil peramalan data out sampel dengan menggunakan metode SARIMA dan SVR menunjukkan bahwa metode SARIMA memiliki nilai MAPE lebih kecil dari pada SVR. Nilai MAPE motode SARIMA adalah 5,33% sedangkan metode SVR sebesar 19,74%. Begitu juga nilai MSE dan MAE dari metode SARIMA lebih kecil dari metode SVR. Dari Penelitian yang dilakukan dapat disimpulkan bahwa model SARIMA merupakan motode yang lebih baik untuk memprediksi jumlah kunjungan wisatawan mancanegara ke Bali.
Membumikan Etika Politik Islam Nabi Muhammad SAW Periode Madinah dalam Konteks Perpolitikan Indonesia
Authors: Hidayat Rahmat , Suwanto Suwanto 
Published: May 2020

<p>Dewasa ini, para elite politis massif melancarkan propaganda politik negetif baik di dunia nyata maupun maya. Persoalannya, ambisi politik yang berlebihan seringkali menghalalkan segala cara untuk mencapai tujuan politik, seperti dengan <em>money politic</em>, <em>hoax</em>, dan <em>hatesp</em><em>e</em><em>ech</em>. Berpolitik yang tidak etis ini berdampak pada instabilitas sosial yang menuai konflik dalam masyarakat. Selain itu, Machiavelisme politik menumbalkan moralitas publik dan mencoreng etika politik yang dijunjung tinggi oleh Pancasila dan ajaran Islam. Studi artikel ini yaitu kualitatif-deskriptif dengan pendekatan sejarah yang diintegrasi-interkoneksikan. Studi ini berusaha mengeksplorasi nilai etika politik Nabi Muhammad SAW periode Madinah di tahun politik Indonesia yaitu dengan merefleksikan nilai-nilai kepemimpinan Nabi Muhammad SAW Periode Madinah, seperti <em>ukhuwah islamiah</em>, persatuan, musyawarah, <em>at-ta’awun</em>, dan keadilan. Aktualisasi nilai-nilai etika politik Islam ini tentu sangat relevan guna mewujudkan kehidupan demokratis yang sehat, bersih, dan santun. Artinya, etika politik Nabi Muhammad SAW periode Madinah dapat diteladani dalam lingkup perpolitikan nasional menuju masyarakat madani menjunjung persatuan-kesatuan dalam kebhinnekaan.</p><p>Kata Kunci: Etika politik Islam, politik Indonesia. </p>
Eventos Neocenozoicos de reorganização de rede de drenagem: um paleovale do Rio das Velhas (Minas Gerais, Brasil) em seu médio curso?
Authors: Pereira Magalhães Jr. Antônio , De Paula Barros Luiz Fernando , Soares Cherem Luis Felipe , Pinto Robson Clayton 
Published: May 2020

Resumo:
O presente trabalho teve como objetivo apresentar e discutir indícios de processos de reorganização da rede de drenagem na média bacia do Rio das Velhas resultantes da reconfiguração de seu vale principal. Nesse sentido, diversos depósitos fluviais foram identificados, descritos e, alguns, datados por Luminescência Opticamente Estimulada (LOE). Os resultados sugerem que a descontextualização de um conjunto de depósitos fluviais em cotas superiores e topos de colinas e a existência de anomalias na organização da rede de drenagem nesse trecho seriam resultantes da mudança do traçado do canal principal do Rio das Velhas no Quaternário Superior.
Palavras-chave: Níveis deposicionais fluviais; Luminescência Opticamente Estimulada; Evolução de rede hidrográfica.

Abstract:
Neocenozic events of drainage network reorganization: a paleovalley of the Velhas River (Minas Gerais, Brazil) in its middle course?This paper aimed to present and discuss clues of reorganization processes of the drainage network in the middle Velhas River catchment resulting from the reconfiguration of its main valley. In this sense, several fluvial deposits were identified, described and, some, dated by Optically Stimulated Luminescence (OSL). The results suggest that the decontextualization of a set of fluvial deposits in higher elevations and tops of hills, as well as the existence of anomalies in the organization of the drainage network in this stretch would results of the change of the main channel of the Velhas River during the Late Quaternary.
Keywords: Fluvial depositional levels; Optically Stimulated Luminescence; Evolution of hydrographic network
Representasi Nilai Kearifan Ranggawarsita pada Kepemimpinan Kepala Dinas Penerangan Komando Armada II dalam Mewujudkan World Class Navy
Authors: Prasadana Afrizal , Purwanto Purwanto 
Published: May 2020

Public relations (PR) has an important focus on the ability of a public relations practitioner to carry out leadership functions. The importance of a quality and value of leadership in the world of public relations (excellent leadership in public relations) in managing an organization. On the other hand, leadership in general is universal, but leadership in public relations practice is contextual. Specifically, the context of this research on how the leadership carried out by the head of the Information Service Fleet Command II represents the value of wisdom contained in the fiber and philosophy of life of Ranggawarsita which is applied to internal and external public in order to realize the Navy World Class. Through the constructivist paradigm, researchers conduct qualitative data collection and are processed through descriptive research. The results of this study indicate, (1). Referring to Panca Pratama, the concept of maintaining good relations between public relations leaders and their public, is in accordance with the concept of Amilala (which means to maintain) (2). In making a decision, the head of the office is the head of the information service or the commander of the Koarmada who takes over and all parts of the organization must carry out. This relates to the Javanese concept of accepting pandum. (3). The head of the information service has a positive attitude and outlook on life, so that subordinates will always melu handarbeni, hangrungkebi melu, mulat sarira hangrasa wani in the sense that all achievements obtained by the organization will always be well developed by subordinates. Keywords: Public Relations, Leadership, Koarmada II, Local Wisdom, Ranggawarsita