bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated stratigraphy of the Guşteriţa clay pit: a key section for the early Pannonian (late Miocene) of the Transylvanian Basin (Romania)
Authors: Botka Dániel , Magyar Imre , Csoma Vivien , Tóth Emőke , Šujan Michal , Ruszkiczay-Rüdiger Zsófia , Chyba Andrej , Braucher Régis , Sant Karin , Ćorić Stjepan , Baranyi Viktória , Bakrač Koraljka , Krizmanić Krešimir , Bartha István Róbert , Szabó Márton , Silye Lóránd 
Published: April 2020

Abstract
The Neogene Transylvanian Basin (TB), enclosed between the eastern and southern Carpathians and the Apuseni Mountains in Romania, is a significant natural gas province with a long production history. In order to improve the (bio) stratigraphic resolution, correlations and dating in the several 100-m-thick upper Miocene (Pannonian) succession of the basin, the largest and most fossiliferous outcrop at Guşteriţa (northeastern part of Sibiu) was investigated and set as a reference section for the Congeria banatica zone in the entire TB. Grey, laminated and massive silty marl, deposited in the deep-water environment of Lake Pannon, was exposed in the ~55-m-high outcrop. The uppermost 25 m of the section was sampled in high resolution (sampling per metres) for macro- and microfossils, including palynology; for authigenic 10Be/9Be dating and for magnetostratigraphy; in addition, macrofossils and samples for authigenic 10Be/9Be isotopic measurements were collected from the lower part of the section as well. The studied sedimentary record belongs to the profundal C. banatica mollusc assemblage zone. The upper 25 m can be correlated to the Hemicytheria tenuistriata and Propontoniella candeo ostracod biozones, the uppermost part of the Spiniferites oblongus, the entire Pontiadinium pecsvaradense and the lowermost part of the Spiniferites hennersdorfensis organic-walled microplankton zones. All samples contained endemic Pannonian calcareous nannofossils, representing the Noelaerhabdus bozinovicae zone. Nine samples were analysed for authigenic 10Be/9Be isotopic measurements. The calculated age data of six samples provided a weighted mean value of 10.42 ± 0.39 Ma. However, three samples within the section exhibited higher isotopic ratios and yielded younger apparent ages. A nearly twofold change in the initial 10Be/9Be ratio is a possible reason for the higher measured isotopic ratios of these samples. Magnetostratigraphic samples showed normal polarity for the entire upper part of the outcrop and can be correlated with the C5n.2n polarity chron (11.056–9.984 Ma, ATNTS2012), which is in agreement with the biostratigraphic data. Based on these newly obtained data and correlation of the biozones with other parts of the Pannonian Basin System, the Guşteriţa section represents the ~ 11.0–10.5 Ma interval, and it is a key section for correlation of mollusc, ostracod, dinoflagellate and calcareous nannoplankton biostratigraphic records within this time interval.
Cancer Incidence in Nigeria and Border Countries
Authors: Baba Isa Abdullahi , Hincal Evren 
Published: April 2020

Many inequalities in cancer incidence exist between Nigeria and border countries. This information is absent or largely unavailable.
Benin, Cameroun, Chad, Niger, and Nigeria cover a population of more than 224,922,000. Globocan data base supplied incidence for 132,939cases of cancer for these countries. The prevalence of Bladder, Colorectum, Kaposi sarcoma, Larynx, Leukaemia, Lip, oral cavity, Liver, Lungwas estimated for the year 2012.The prevalence of Nasopharynx, Non – Hodgkin, Lymphoma, Pancrease, Prostrate, Stomach combined was also estimated for the same year.
The most common male cancer found in Nigeria and border countries is Prostate cancer, seconded by Liver. In this study also we found Breast cancer to be the most common in females, followed by Cervical Cancer. Larynx and Kaposi sarcoma are found to be the least common cancer for both males and females in the population.
In conclusion, the findings of this study gave lights to some guidelines to aid the design of cancer control programs in Nigeria and border countries. The spectrum of the cancers is dominated by the breast & Cervix uteri for females, while Prostate & Liver for males.
Community-Engaged Research (CER) as the Avenue to Promoting Well-being and Recovery in Drug Court
Authors: Gallagher John Robert , Nordberg Anne , Minasian Raychel , Szymanowski Sydney , Carlton Jesse , Fee Kristin , Woodward Miller Jane , Horsley John , Paiano Tara 
Published: April 2020

Drug courts are an alternative to incarceration for individuals who have substance use disorders and have been arrested for drug-related crimes (e.g. possession of a controlled substance). The first drug court began in 1989 in Florida and it is estimated that there are over 3,000 drug courts now operating throughout the United States. This community-engaged research (CER) evaluated the St. Joseph County (Indiana) drug court by identifying who was most likely to graduate, who was most likely to recidivate, and whether drug court or probation was more effective at reducing criminal recidivism. Furthermore, although drug courts are found in many communities, research rarely describes the process used to develop and implement CER. Therefore, this article also highlights the collaborative process used in this drug court evaluation. The findings from this study suggest that the St. Joseph County (Indiana) drug court is an effective program at reducing criminal recidivism and a valuable resource for individuals who have substance use disorders, the community, and other stakeholders. Drug court participants were less likely to recidivate than probationers, and a lower recidivism rate clearly equates to many benefits to the community. The article concludes with community-based implications, such as starting recovery support groups that are welcoming to individuals who receive medication-assisted treatment (MAT), marketing drug court to racial and ethnic minorities to increase their representation in drug court, and disseminating research findings throughout the community via local news stories and public lectures.
Análisis de las muertes maternas por hemorragia en el departamento de Antioquia, Colombia. Años 2004 y 2005
Authors: Vélez-Álvarez Gladis Adriana , Gómez-Dávila Joaquín Guillermo , Zuleta-Tobón John Jairo 
Published: April 2020

Objetivo: identiﬁcar los factores que predisponen a la mortalidad materna por hemorragia obstétrica en el departamento de Antioquia (Colombia) durante los años 2004-2005.Metodología: estudio descriptivo retrospectivo con componente cuantitativo y cualitativo. El análisis de los casos se realizó utilizando la metodología del “Camino para la supervivencia a la muerte materna” que identiﬁca tres retrasos, 1: de la comunidad para identiﬁcar la enfermedad o consultar, 2: diﬁcultades de acceso al servicio de salud y 3 deﬁciencias en la calidad o en la oportunidad de la atención.Resultados: la principal causa de hemorragia obstétrica fue la hemorragia posparto. Un 29% de las pacientes que fallecieron después de un parto vaginal tuvieron su parto en casa. El 100% de las muertes se consideraron evitables y los principales factores detectados estuvieron dentro de las categorías retraso 1 (43%) y 3 (88%). En el tipo 3, los principales fueron: la subvaloración de los cuadros clínicos, las conductas inoportunas y el tratamiento inadecuado de las pacientes: no se aplica el manejo activo del alumbramiento de manera universal, manejo inadecuado del shock y retraso en la administración de hemoderivados.Conclusiones: la hemorragia obstétrica es el principal problema en mortalidad materna en el departamento de Antioquia y los aspectos a mejorar tienen que ver con la implementación del manejo activo del alumbramiento, un diagnóstico temprano y un tratamiento agresivo del shock y la reanimación.
Impact of aggressive blood pressure reduction on kidney function after renal denervation: long-term outcome
Authors: Panarina S. A. , Yudina Yu. S. , Ionov M. V. , Avdonina N. G. , Emelyanov I. V. , Vasileva E. U. , Kitaeva E. A. , Zverev D. A. , Zvartau N. E. , Konradi A. O. 
Published: April 2020

Objective. To investigate the dynamics of renal function in patients with resistant arterial hypertension after renal denervation depending on the degree of central and peripheral blood pressure (BP) reduction and the baseline state of the kidneys.Design and methods. A total of 22 patients (mean age 56,1 ± 10,2 years, 9 males) with treated resistant hypertension undergoing bilateral renal denervation (RDN) (Symplicity RDN System, Medtronic, USA) were included. Office BP measuring, 24-hour ambulatory BP monitoring (ABPM) (SpaceLabs 90207, USA), applanation tonometry (SphygmoCor, AtCor Medical, Australia) with the calculation of central aortic blood pressure (CAP), Doppler ultrasonography (Vivid 7 dimension) were obtained at baseline and at 1, 3, 6, 12, 18 and 24 months after RDN. Urine levels of NGAL (neutrophil gelatinase-associated lipocalin), KIM-1 (kidney injury molecule 1), L-FABP (Liver-type fatty acid binding protein), albuminuria and serum levels of сystatin C (sCysC) and creatinine (sCr) were measured by quantitative enzyme immunoassay at baseline and at 1, 3, 6, 12, 18 and 24 months after RDN. Glomerular filtration rate was estimated by the level of sCr and sCysC by CKD-EPI formula.Results. All patients were divided into 3 groups according BP reduction: 1 — BP increase above 0 mm Hg; 2 — BP reduction from 0 to –30 mm Hg; 3 — BP reduction by > 31 mm Hg. An increased sCysС was registered in a group with decreased 24-hour systolic BP (1,06 ± 0,41; 0,93 ± 0,18 and 1,22 ± 0,23 ng/mL; F = 2,882; р = 0,04) and increased urine KIM-1 level — in a group with decreased office diastolic BP (2,18 ± 1,94; 1,53 ± 1,02 and 4,41 ± 0,97 pg/mL; F = 3,663; р = 0,03) at 3-month follow-up. An increased sCr level was registered in a group with decreased 24-hour systolic BP (78,3 ± 3,7; 88,2 ± 6,8 and 142,00 ± 8,8 μmol/L; F = 61,987; p = 0,004) and diastolic CAP (83,4 ± 8,2; 82,0 ± 8,0 and 142,0 ± 9,4 μmol/L; F = 23,476; p = 0,01), also an increased urine L-FABP level — in a group with decreased office diastolic BP (3531,3 ± 1795,0; 997,5 ± 1096,8 and 7351,7 ± 3297,0 pg/mL; F = 12,103; p = 0,002) at 6-month follow up.Conclusions. Renal function worsening in patients during the period of maximum BP lowering may be associated with an excessive BP reduction. Therefore, we can suggest the occurrence of the J-curve phenomenon in relation to the kidneys.
Bombesin-like peptides are able to affect central histamine-induced resuscitating effect in haemorrhage-shocked rats
Authors: Jasikowska Karolina , Rybus-Kalinowska Barbara , Klose Aleksandra , Nowak Damian , Jochem Jerzy 
Published: April 2020

Wstęp:Pobudzenie ośrodkowego układu histaminergicznego wywołuje działanie resuscytacyjne u szczurów we wstrząsie krwotocznym. Skoro podawana dożylnie bombezyna wykazuje podobne działanie, a receptory bombezynowe są obecne w strukturach ośrodkowego układu nerwowego, odpowiedzialnych za regulację czynności układu krążenia, celem pracy było zbadanie wpływu zablokowania receptorów bombezynowych na efekty krążeniowe wynikające z podania do komory bocznej mózgu (icv) histaminy we wstrząsie krwotocznym u szczurów.Materiał i metody:Badania przeprowadzono u szczurów, samców szczepu Wistar w znieczuleniu ogólnym (ketamina 100 mg/kg + ksylazyna 10 mg/kg, dootrzewnowo). Zastosowano model odwracalnego wstrząsu krwotocznego ze średnim ciśnieniem tętniczym (MAP) 30–35 mmHg. Niezwłocznie po zakończeniu krwawienia podawano icv antagonistów receptorów bombezynowych/0,9% roztwór NaCl, a 5 min później tą samą drogą histaminę (50 nmol) bądź 0,9% roztwór NaCl.Wyniki:Utrata krwi prowadziła do obniżenia ciśnienia tętna (PP), częstości rytmu serca (HR) i przepływu krezkowego krwi (MBF). Histamina wywoływała działanie presyjne ze wzrostem PP i MBF. Efekty działania histaminy były częściowo hamowane przez [D-Phe12,Leu14]-bombezynę i BIM 23042, odpowiednio nieselektywnego antagonistę receptorów bombezynowych oraz selektywnego blokera receptorów bombezynowych typu 1 (BB1). W grupach kontrolnych nie stwierdzono wpływu antagonistów receptorów bombezynowych na mierzone parametry układu krążenia.Wnioski:Endogenne peptydy bombezynopodobne, działając poprzez receptory BB1, mogą wpływać na wywoływane przez ośrodkowo działającą histaminę działanie resuscytacyjne we wstrząsie krwotocznym u szczurów.
Information and Communications Technology and Education Customized for Fathers of Preterm Infants
Authors: Kim Hyung Nam 
Published: April 2020

PurposeAlthough various educational technology interventions have been introduced to support parents of preterm infants, the interventions tend to focus on mothers over fathers. This study aims to advance understanding of the concerns and needs of fathers and seek opportunities of information technology to support them.Design and SampleA convenience sampling method recruited 18 parents (i.e., ten mothers and eight fathers of preterm infants) for interviews. The interview transcripts were analyzed by the inductive content analysis method.Main Outcome VariableThe analysis identified two main themes (i.e., customized education, learning styles and tools preferred by fathers) and five subthemes (i.e., infant care, self-care, self-regulated online learning, adaptive user interfaces of online education modules, and hands-on learning with multimedia).ResultsThe interviewed parents emphasized the importance of education customized for the fathers of preterm infants, and argued that an e-learning system has the potential to fulfill the fathers' educational needs.
Preliminary Psychometrics of the Knowledge and Attitudes Toward SBAR Instrument (KA-SBAR)
Authors: Cooper Denise , Clark Patricia C. 
Published: April 2020

BackgroundWhen measuring new practice approaches for improving patient safety in the clinical setting, researchers need instruments with evidence of reliability and validity.ObjectiveThe purpose of this analysis was to examine the reliability and validity of an instrument to assess knowledge and attitudes toward communication using situation-background-assessment-recommendation (SBAR; KA-SBAR).MethodsThis psychometric analysis was conducted with data from an interprofessional simulation-based learning experience with doctor of nursing practice students (n = 19) and physical therapy students (n = 52). Internal consistency reliability and construct validity tests including factor analysis for the KA-SBAR were conducted.ResultsThe KA-SBAR instrument had adequate internal consistency reliability and evidence of construct validity, including identification of two factors that explained 70% of the instrument's variance. However, there may be a ceiling effect of scores, making it difficult to show change.ConclusionsThe KA-SBAR instrument may be useful in assessing clinicians' perceptions of SBAR communication in education and practice settings.Implications for NursingWhen selecting data collection measures, nurses need to carefully consider the purpose of the measure and evidence of the instrument's reliability and validity. Educators need to consider the clinical expertise of the students in designing challenging simulations to advance learning.
Peningkatan Hasil Belajar Matematika melalui Media Realia pada Siswa Kelas 2 SD
Authors: Sari Annisa Herlida 
Published: April 2020

The aim of this research is to improve the results of learning math students second grade through the application of media realia. The research was implemented on SDN 1 Kalianda, South Lampung. This study used class action research conducted through two cycles, a cycle of comprising planning, action, observation and reflection. The subject of research is a whole number of second grade student SDN 1 Kalianda having the mathematical value helpdown KKM totaled 12 student. Analysis of the percentage data used in this study was based on an agreement with a researcher and collaborator is using percentage increase reched 71% atthe end of the cycle. Analysis of data obtained from the result of percentage increase at the end of the cycle reached 84,33%. The end result of a whole analysis percentage data is an inrease more than 71%. Based on an increase in the percentage of this research, all student have reached percentage inrease reahed 71%, the can be expressed that hypotesis accepted. It could be concluded that the use of the media realia can enchange the results of learning math student second grade of elementary school student.
Burden of stillbirths and associated factors in Yirgalem Hospital, Southern Ethiopia: a facility based cross-sectional study
Authors: Mengesha Sintayehu , Dangisso Mesay Hailu 
Published: April 2020

Abstract
Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden for parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia Methods : A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of pregnant women from a hospital delivery registry. Bivariate analysis was employed to assess the association between independent and dependent variables using chi-square with significant p-value. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding.. Results : Of 374 reviewed records of pregnant women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Fifteen, 15 (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (<2500grams) (adjusted odds ratio (AOR): 10.70, 95% CI 3.18-35.97) than normal birth-weight babies (2500-<4000). Pregnant women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76-84.12) more likely to have stillbirths than pregnant women without a prolonged labour. Pregnant women with obstetric complications were 19.8 times more likely to have stillbirths than pregnant women without obstetric complications. Similarly, pregnant women with at least 2 pregnancies were more likely to have stillbirths than pregnant women with less than two pregnancies (AOR: 4.39, 95% CI 1.21-15.85). Conclusion: We found a high burden of stillbirths in the study setting. Modifiable risk factors contributed to a higher risk of stillbirths; therefore, tailored interventions such as early identification and management of prolonged labour and obstetric complication at each level of health system could avert preventable stillbirths.
Wounds at risk of tetanus: unexpected level of underimmunization in a patient cohort
Authors: Piccini Gaia Bavestrello , Cavenaile Jean-Christophe , Bressan Maria Antonietta 
Published: April 2020

Abstract
Background: Tetanus is an acute and potentially fatal disease caused by Clostridium tetani, an extremely resilient pathogen. This bacterium can contaminate traumatic wounds which account for approximately 5.4% of all visits to the Emergency Department. According to several surveillance programs, the incidence of clinical tetanus in Italy is tenfold higher than in other industrialised countries. In 2010, Italy accounted for 57 of the 74 confirmed cases reported within the European Union.Methods: The study analysed data from 1094 patients who presented to the Emergency Department of the Fondazione IRRCS Policlinico San Matteo between April 2016 and November 2017 with wounds potentially at risk of infection with Clostridium tetani. Results: Data showed that, in conformity with the literature, the elderly (> 60 years old) constitute a high-risk category, with 219 unprotected individuals out of 238. Also, among patients aged more than 60 years old, there was a statistically significant difference between female and male patients. From the comparative analysis of the data however, it was surprisingly found that even younger patients are lacking protective immunity. Conclusions: When considering other medical systems, both European and non-European ones, and analysing their guidelines for the prevention of tetanus infection, the necessity of adopting a well-defined algorithm becomes evident. This, in order to avoid the excessive administration of prophylaxis, as well as to allow to put in place the necessary preventive measures for each patient. This study highlights the need for greater patient and clinician awareness, and for an improvement in record keeping and management of the documentation related to vaccinations. The analysed data also suggest the need for conducting awareness campaigns on the topic of vaccines and vaccine preventable infections. Patients should be made aware of the importance of keeping track of their own immunization status, and of remembering the date of the last administration of the vaccine or, of carrying around their vaccination card.
Patient’s travel distance to specialised cancer diagnostics and the association with the general practitioner’s diagnostic strategy and satisfaction with the access to diagnostic procedures: an observational study in Denmark
Authors: Virgilsen Line Flytkjær , Hvidberg Line , Vedsted Peter 
Published: April 2020

Abstract
Background: Research indicate that when general practitioners (GPs) refer their patients for specialist care, the patient often has long distance. This study had a twofold aim: in accordance to the GP’s suspicion of cancer, we investigated the association between: 1) cancer patient’s travel distance to the first specialised diagnostic facility and the GP’s diagnostic strategy and 2) cancer patient’s travel distance to the first specialised diagnostic facility and satisfaction with the waiting time and the availability of diagnostic investigations.Method: This combined questionnaire- and registry-based study included incident cancer patients diagnosed in the last six months of 2016 where the GP had been involved in the diagnostic process of the patients prior to their diagnosis of cancer (n=3,455). The patient’s travel distance to the first specialised diagnostic facility was calculated by ArcGIS Network Analyst. The diagnostic strategy of the GP and the GP’s satisfaction with the waiting times and the available investigations were assessed from GP questionnaires. Results: When the GP did not suspect cancer or serious illness, an insignificant tendency was seen that longer travel distance to the first specialised diagnostic facility increased the likelihood of the GP using ’wait-and-see’ approach and ’medical treatment’ as diagnostic strategies. The GPs of patients with travel distance longer than 49 kilometres to the first specialised diagnostic facility were more likely to report dissatisfaction with the waiting time for requested diagnostic investigations (PR: 1.98, 95% CI: 1.20-3.28).Conclusion: A insignificant tendency to use ‘wait-and-see’ and ‘medical treatment’ were more likely in GPs of patients with long travel distance to the first diagnostic facility when the GP did not suspect cancer or serious illness. Long distance was associated with higher probability of GP dissatisfaction with the waiting time for diagnostic investigations.