bluuebunny/crossref_metadata_2025_split huggingface dataset:
MODEL PENDIDIKAN KARAKTER BERBASIS LITERACY GARDENS DI PAUD
Authors: Sutini Ai , Halimah Leli , Ismail Mohamad Helmi 
Published: June 2020

Kemajuan suatu bangsa di masa depan dalam berbagai sektor kehidupan, sangat tergantung pada generasi muda yang mungkin saat ini masih berada pada kelompok anak usia dini. Kelompok usia tersebut akan menjadi investasi, dan akan menjadi sumber daya manusia yang berkualitas apabila orang dewasa (seperti orang tua, guru) mampu membangun potensi kreativitas sejak dini. Adapun, yang menjadi permasalahannya berdasarkan hasil studi pendahuluan terhadap banyak Taman Kanak-kanak (TK) pada umumnya pembelajaran di TK belum sesuai dengan tahap perkembangan anak, mengingat pembelajaran lebih banyak mengkondisikan anak-anak bermain di dalam kelas, agar anak cepat dapat membaca, menulis, dan berhitung. Dengan kondisi tersebut, menjadi sangat jarang anak-anak TK bermain di halaman sekolahnya, sementara dari hasil kajian literature bahwa bermain di lingkungan outdoor classroom, seperti di halaman sekolah memberikan banyak manfaatnya bagi berkembangnya seluruh aspek perkembangan anak termasuk sangat potensial untuk membentuk karakter anak. Menyikapi kondisi realitas dan hasil kajian literature, maka penelitian ini bertujuan untuk mengembangkan model pendidikan karakter berbasis literacy gardenss di PAUD. Penelitian ini menggunakan desain penelitian kualitatif yang bersifat studi kasus.Sesuai dengan karakteristik studi kasus, pengumpulan data penelitian, digunakan beberapa instrument penelitian, yaitu observasi, catatan lapangan, dokumen hasil karya siswa, photo, rekaman dengan menggunakan video, wawancara, dan penilaian. Setiap instrument tersebut digunakan saat berlangsungnya proses pembelajaran. Adapun analisis data dilakukan meliputi kegiatan: penjodoan pola, pembuatan eksplanasi, dan analisis deret waktu. Untuk memperoleh kesimpulan penelitian, analisis data dilakukan secara berkelanjutan setiap kali proses pembelajaran, yang dilanjutkan dengan interpretasi hasil analisis data melalui konfrensi secara berkolaborasi dengan guru. Selain laporan penelitian sebagai kelengkapan hasil penelitian, luaran yang diharapkan dari penelitian ini adalah: (a) menghasilkan dokumen prototype model, (2) menghasilkan buku ajar, (c) menghasilkan CD pembelajaran sesuai model, (d) artikel untuk diajukan pada jurnal nasional atau internasional yang terakreditasi. Kata kunci: Pendidikan karakter, literacy gardenss, pendidikan anak usia dini
PENGARUH MODEL PEMBELAJARAN GROUP INVESTIGATION MELALUI LESSON STUDY TERHADAP PENGUASAAN KONSEP IPA SISWA
Authors: Sudiasih Ni Nengah , Wibawa I Made Citra , Margunayasa I Gede 
Published: June 2020

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran group investigation melalui lesson study terhadap penguasaan konsep IPA siswa kelas IV semester genap SD Gugus VII Kecamatan Kubutambahan Kabupaten Buleleng Tahun Pelajaran 2018/2019. Metode penelitian ini eksperimen semu dengan desain penelitin non-equivalent control onyl post test control group desain. Populasi penelitian ini adalah seluruh siswa kelas IV SD Gugus VII Kecamatan Kubutambahan. Sampel penelitian diambil menggunakan teknik random sampling undian, sehingga diperoleh SDN 1 Bontihing sebagai kelas kontrol dan SDN 2 Bontihing sebagai kelas eksperimen. Data ini dikumpulkan menggunakan tes objektif pilihan ganda, kemudian dianalisis menggunakan uji-t. Berdasarkan uji hipotesis diperoleh nilai thitung 2,65ttabel 2,01. Hal ini disebabkan oleh langkah-langkah dari model pembelajaran group investigation dan penerapan lesson study sehingga pembelajaran menjadi berpusat pada siswa. Dengan demikian disimpulkan bahwa terdapat pengaruh yang signifikan model pembelajaran group investigation melalui lesson study terhadap penguasaan konsep IPA siswa kelas IV semester genap SD Gugus VII Kecamatan Kubutambahan Kabupaten Buleleng Tahun Pelajaran 2018/2019.
IMPLEMENTASI KURIKULUM 2013 DI SEKOLAH INKLUSI SEKOLAH DASAR INTERNATIONAL ISLAMIC SCHOOL (INTIS) YOGYAKARTA
Authors: Rahmatika Nuniek , Ratrianasari Dani , Widodo Hendro 
Published: June 2020

UNESCO mecetuskan bahwa educational for all atau pendidikan untuk semua atau pendidikan disemua kalangan yang berarti bahwa semua siswa berhak mendapatkan apa yang dicita-citakan, dan tanpa diskriminasi. Penelitian ini bertujuan untuk mengetahui bagaimana kurikulum 2013 dapat diimplementasikan di sekolah inklusi. Penelitian ini menggunakan metode kualitatif yang bertujuan untuk memperoleh gambaran secara menyeluruh dan mendalam mengenai isu atau fenomena di sekolah inklusi. Wawancara, observasi dan dokumentasi. Subjek penelitian yaitu wakil kepala sekolah bagian kurikulum, koordinator inklusi, wali kelas dan guru pendamping khusus. Hasil penelitian penunjukkan bahwa: 1) Penerapan kurikulum 2013 di sekolah inklusi, dimulai pada perencanaan, pembuatan RPP dan silabus dibuat bersama-sama guru pendamping khusus. penyususnan RPP dan silabus dilakukan sesuai dengan hasil assessmen psikolog berdasarkan apa yang dibutuhkan oleh siswa berkebutuhan. 2) Perbedaan dan kesamaan kurikulum 2013 pada siswa berkebutuhan khusus. berdasarkan hal tersebut, dalam RPP masih belum ada perbedaan dan pemisahan antara siswa berkebutuhan dan siswa reguler. Perbedaan tersebut terletak pada penyampaian metode yang dilakukan oleh guru pendamping khusus. 3) Evaluasi yang diterapkan pada kurikulum 2013 untuk siswa berkebutuhan khusus dengan melakukan laporan perkembangan siswa berkebutuhan bekerjasama dengan guru pendamping khusus. Guru pendamping akan menganalisis perubahan-perubahan yang terjadi pada siswa selama proses belajar mengajar berlangsung.
SATISFACTION OF THE E-MONPRAKERIN MODEL BASED ON THE ANDROID SYSTEM FOR MONITORING VOCATIONAL STUDENT INTERNSHIPS
Authors: Sutikno  , Baedhowi  , Siswandari  , Roemintoyo  
Published: June 2020

Purpose of the study: This study aims to find out the implementation of electronic monitoring of internship (e-monPrakerin) in industrial revolution 4.0 and society 5.0 and user satisfaction in using e-monPrakerin android-based in monitoring internship of vocational students.
Methodology: The research method is a descriptive survey of the use of e-monPrakerin for electronic internship monitoring. Respondents are the teachers at Mondokan 1 Vocational High School as supervisors of the student internship program. The instrument used was the USE questionnaire for e-monPrakerin implementation. Data analysis techniques using descriptive analysis with percentages.
Main Findings: The results showed that the use of an e-monPrakerin android-based system for electronic internship monitoring 1) good use (74.52%); 2) good ease of use (80.09%); 3) it's easy to learn (84.94%); 4) users are very satisfied (81.97%). Electronic internship monitoring using Android-based e-monPrakerin satisfies application users.
Applications of this study: Implementation of research results can be used to monitor students' industrial work practices so that their implementation can be monitored effectively and efficiently.
Novelty/Originality of this study: Facing the disruption era of the industrial revolution 4.0, all activities were carried out by utilizing information technology, at a lower cost and a high level of quality. The e-monPrakerin model was created to answer these challenges on the basis of information technology so that it can save costs, be more practical, faster, and of high quality.
The Effect of Human Resource Competency, Work Culture and Utilization of Information Technology to Performance of Employees
Authors: Indiyaningsih Kasih Mey Hana 
Published: June 2020

The development of technology nowadays is so rapid along with the development of technology-based information systems, this is what causes rapid changes in various fields. Information technology in this case is one pillar of success in the era of globalization, policy making in companies is demanded to be as efficient as possible to continue to maintain the survival of the organization. Analysis of data using linear regression. Data collection techniques using questionnaires, interviews, non-participant observation. The population of this study is the Aparatur Sipil Negara in the Badan Kepegawaian Daerah Kabupaten Lumajang . In sampling using a saturated / census sampling technique. Because the number of ASN is less than 100 people, namely 49 people. Thus the entire population is sampled in this study.
Keywords: Employee Performance, Information Technology Utilization
Numerical study of the dynamics of synthesis gas adsorption separation
Authors: Akulinin E. I. , Golubyatnikov O. O. , Dvoretsky D. S. , Dvoretsky S. I. 
Published: June 2020

A numerical study of the dynamics of pressure swing adsorption process for synthesis gas separation and hydrogen concentration was carried out. The influence of regime parameters (compressor and vacuum pump outlet pressures, duration of the "adsorption-desorption" cycle, backflow coefficient) and design parameters (height of the adsorbent bulk layer and the internal bed diameter) on the recovery and purity of hydrogen, plant performance in a given range of changes in the temperature, composition and pressure of the initial gas mixture was studied. It is found that when the hydrogen content decreases from 68 to 48 vol. % and a simultaneous increase in the carbon dioxide content in the initial gas mixture from 27 to 47 vol. % required hydrogen purity value at 99.99 vol. % can be achieved by reducing the pressure at the outlet of the vacuum pump from 0.75?105 to 0.5?105 Pa. At the same time, the duration of the adsorption stage increases from 120 to 150 seconds, and the degree of hydrogen extraction decreases from 55 to 52% due to an increase in the proportion of the flow selected for the regeneration of the adsorbent. Increasing the temperature of the initial gas mixture from 293 to 323 K leads to the need to reduce the duration of the adsorption stage from 148 to 42 s due to a decrease in the equilibrium concentrations of carbon dioxide and monoxide in the adsorbent.
iTRAQ-based quantitative proteomic of tobacco (Nicotiana tabacum L.) identified major host proteins involved in photosystems throughout the aging process
Authors: He Conglian , Sun Shubin , Tang Yun , He Chenggang , Li Pengfei , Xu Tianyang , Zhao Gaokun , Zou Congming , Lin Zhonglong , Chen Yi 
Published: June 2020

Abstract
The authors have withdrawn this preprint due to author disagreement.
Dezocine inhibits cell proliferation, migration and invasion by targeting CRABP2 in ovarian cancer
Authors: Zhang Chuanfeng , Pan Ruirui , Ma Shuangshuang , Xu Shoucai , Wang Baosheng 
Published: June 2020

Abstract
Background: Previous studies have shown that some anesthesia drugs can inhibit tumor growth and metastasis. As a clinical anesthetic drug, dezocine has been reported to play an important role in immune function. However, the effects of dezocine on ovarian cancer cell growth and metastasis are not fully understood. Results: In this study, we found that dezocine dose-dependently inhibited the viability of ovarian cancer ES-2 and SKOV3 cells. Dezocine suppressed the migration and invasion abilities of ovarian cancer cells and promoted apoptosis. Moreover, the Akt/mTOR signaling pathway was also inhibited by dezocine. Furthermore, the mechanism study showed that dezocine could significantly inhibit the expression of CRABP2, and CRABP2 overexpression reversed the inhibitory effects of dezocine on ovarian cancer cell proliferation and migration. Conclusions: In conclusion, dezocine has significant anti-tumor effects on the growth and metastatic potential of ovarian cancer cells, and CRABP2 functions as a downstream effector of dezocine.
Exploring the Effective Factors on Fires Related Injuries in Residential Buildings Inhabitants: Findings from a Paradigm Model
Authors: Shokouhi Mohammadreza , Nasiriani Kadijeh , Ardalan Ali , Khorasani-Zavareh Davoud 
Published: June 2020

Abstract
Background

Fires is one of the most important hazards leading to human casualties as well as financial losses in the world, mostly in low- and middle- income countries. This study aims to provide in-depth information on fires in residential buildings and explain the safety process against fires in Iran.
Methods

This study has a qualitative study design using a grounded theory principle, recommended by Strauss and Corbin, and using the Paradigm Model. The data were collected via in-depth interviews with 27 participants, including injured patients, health professionals, firefighters and other stakeholders in Iran, who have practical experience or theoretical knowledge about management and action after fires. Data were analyzed based on a grounded theory approach, using the Paradigm model.
Results

Synergistic building safety deficiency and qualitative relief defects were identified as the center of this study. This reflects participants' experience essence on the barriers to preventing fires related injuries in residential areas in Iran. These issues are debatable at various levels, from local and national policy to individual characteristics and behaviors of people and inhabitants of residential buildings against fires.
Conclusions

The safety of building’s occupants requires the improvement of many factors at the local and national level. Safety construction of buildings, urban infrastructure and public education should be taken into consideration to promote community safety.
Luteolin Inhibits Respiratory Syncytial Virus Replication by Regulating the MiR-155/SOCS1/STAT1 Signaling Pathway
Authors: Wang Saisai , Ling Yiting , Yao Yuanyuan , Zheng Gang , Chen Wenbin 
Published: June 2020

Abstract
Background
Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infection in infants, children, immunocompromised adults, and elderly individuals. Currently, there are few therapeutic options available to prevent RSV infection. The present study aimed to investigate the effects of luteolin on RSV replication and the related mechanisms.
Material and methods
We pretreated cells and mice with luteolin before infection with RSV, the virus titer, expressions of interferon (IFN)-stimulated genes (ISGs), RSV-F and production of IFN-α and IFN-β were determined by plaque assay, RT-qPCR and ELISA. The activation of Janus kinase (JAK)- signal transducer and activator of transcription 1 (STAT1) signaling pathway was detected by Western blotting and luciferase assay. Proteins which negatively regulates STAT1 was determined by Western blotting. Then cells were transfected with suppressor of cytokine signaling 1 (SOCS1) plasmid and virus replication and ISGs expression was determined. Luciferase reporter assay and Western blotting was performed to detect the relationship between SOCS1 and miR-155.
Results
Luteolin inhibited RSV replication, as shown by the decreased viral titer and RSV-F mRNA expression both in vitro and in vivo. The antiviral activity of luteolin was attributed to the enhanced phosphorylation of STAT1, resulting in the increased production of ISGs. Further study showed that SOCS1 was downregulated by luteolin and SOCS1 is a direct target of microRNA-155 (miR-155). Inhibition of miR-155 rescued luteolin-mediated SOCS1 downregulation, whereas upregulation of miR-155 enhanced the inhibitory effect of luteolin.
Conclusion
Luteolin inhibits RSV replication by regulating the miR-155/SOCS1/STAT1 signaling pathway.
Advancing methodology for scoping reviews: recommendations arising from a scoping literature review (SLR) to inform transformation of children and adolescent mental health services.
Authors: Anderson Joanna K , Howarth Emma , Vainre Maris , Humphrey Ayla , Jones Peter B. , Ford Tamsin J. 
Published: June 2020

Abstract
Background: There is consensus that health services commissioning and clinical practice should be driven by scientific evidence. However, workload pressures, accessibility of peer reviewed publications and skills to find, appraise, and synthesise relevant evidence are often cited as barriers to uptake of research evidence by practitioners and commissioners alike. In recent years a growing requirement for rapid evidence synthesis to inform commissioning decisions about healthcare service delivery and provision of care contributed to an increasing popularity of scoping literature reviews (SLRs). Yet, published guidelines for conducting and reporting SLRs are still relatively scarce. Methods: The exemplar review used as a worked example aimed to provide a readily available, comprehensive, and user-friendly repository of research evidence for local commissioners to help them make evidence-informed decisions about redesigning East of England Children and Adolescent Mental Health Services. In conducting the review, we were broadly guided by Arksey and O’Malley’s framework, however some modifications were made at different stages to better reflect the largely pragmatic objective of this review. This paper compares the methodology used with existing methodological frameworks for scoping studies, to add to the existing knowledge base.Results: We proposed the following advancements to the existing SLR frameworks: (i) Assemble a research team with complementary skills and expertise; (ii); Draw on expertise of external partners, particularly practitioners, decision-makers and commissioners who will be translating findings into practice; (iii) Pre-register the review protocol. Keep a detailed record of all steps and decisions and consider how they would impact on generalisability and utility of review findings; (iv) Use systematic procedures for literature searchers, selection of studies, data extraction and analysis; (v) If feasible, appraise the quality of included evidence; (vi) Be transparent about limitations of findings.Conclusions: Despite some methodological limitations, scoping literature reviews are a useful method of rapidly synthesising a large body of evidence to inform commissioning and transformation of CAMHS. SLRs allow researchers to start with a broader questions, to explore the issue from different perspectives and perhaps find more comprehensive solutions that are not only effective, but also accounted for their feasibility and acceptability to key stakeholders.
miR-132-3p mediates Functions of Vascular Smooth Muscle Cells through targeting PTEN expression and ERK1/2 pathway
Authors: liu Guang , He zhijun , zhang Rong , Yang ganglion , Huang sheng , Lu huaxiang , lu xinwu , luo yanli , liu xiaobing 
Published: June 2020

Abstract
Background

This study was aimed to investigate the functional role of the microRNA (miR)-132-3p in rat vascular smooth muscle cells (VSMCs) and the potential mechanisms in abdominal aortic aneurysm (AAA).
Methods

VSMCs were transfected with miR-132-3p mimics and inhibitors, and the effects of miR-132-3p on VSMCs proliferation, migration were assessed by CCK-8 assay and Boyden chamber cell invasion assay, respectively. miRNA targets were determined using bioinformatics and luciferase reporter assays. The protein expression of phenotype markers and related signaling pathways were detected by Western blot.
Results

Overexpression of miR-132-3p in VSMCs attenuated VSMCs proliferation and migration. Conversely, the opposite effect was obtained with the inhibition of miR-132-3p. We further demonstrated that miR-132 could significantly promote the expression of VSMCs marker genes ACTA2 and MYH1. Reporter assays and western blot validated that PTEN as a direct target of miR-132-3p in VSMCs. Besides, miR-132-3p overexpression could also promote the expression of ras and c-myc, and activate the phosphorylation levels of ERK1/2.
Conclusions

These results indicate that miR-132-3p is a critical regulator in maintaining normal functions of VSMCs through PTEN-ERK1/2 axis. Restoring expression of miR-132-3p may serve as a potential therapeutic approach for treatment of AAAs.
Single and multiple suicide attempts: Prevalence and correlates in school-going adolescents in Liberia in 2017
Authors: Pengpid Supa , Peltzer Karl 
Published: June 2020

Abstract
Background: This investigation aimed to estimate the prevalence and its correlates of single and multiple suicide attempts among adolescents in Liberia.Method: Cross-sectional nationally representative data were analysed from 2,744 adolescents (18 years median age) that participated in the “2017 Liberia Global School-Based Student Health Survey (GSHS).”Results: Results indicate that 33.7% of students had made a suicide attempt in the past 12 months (16.5% single and 17.2% multiple suicide attempts). In adjusted multinomial logistic regression analysis, having no close friends, loneliness, having been frequently physically attacked, ever used amphetamine and fast food intake were associated with multiple suicide attempts in the past 12 months. In addition, having been frequently in a physical fight and current tobacco use were associated with single suicide attempt. In sex stratified analyses, in addition, among boys frequent bullying victimization and among girls, parental tobacco use and parents never or rarely check on home work were associated with multiple suicide attempts. Multiple psychosocial distressors, multiple social-environmental factors and multiple health risk behaviours were associated with single and multiple suicide attempts.Conclusion: One in three students had made suicide attempt in the past 12 months (one in six students multiple suicide attempts) and several associated variables were detected which can aid in designing intervention strategies.
Prognosis of lower respiratory tract infected patients with virus detected in bronchial alveolar lavage fluid: a retrospective observational study
Authors: Zhang Yuan , Huang Qiuping , Zhou Zhigang , Xie Yun , Li Xianchen , Jin Wei , Wang Ruilan 
Published: June 2020

Abstract
Background and Objectives The influence of virus detected in BALF is still debating. This study aimed to compare the prognosis of lower respiratory tract infected patients with virus detected in bronchial alveolar lavage fluid (BALF) and patients with virus undetected by using metagenomic next-generation sequencing technology.Methods This was a retrospective cohort study. 53 patients with lower respiratory tract infection were enrolled. BALF samples were collected from each patient and sent to perform mNGS pathogenic test in the study. According to the results of mNGS test, patients were divided into virus-detected group and virus-undetected group. In the meanwhile, patients’ clinical information, medical history, disease severity scores, parameters of organ function at the day of ICU admission, prognosis, hospital length of stay, ICU length of stay and needs for medical support were also collected.Results 39.6 percent (21/53) of the BALF samples were virus nucleic acid positive. Mortality rate, tracheotomy rate, mechanical ventilation supporting time, blood transfusion rate were significantly higher in virus-detected group than that in virus-undetected group. Virus-detected was closely related to hospital and ICU survival time.Conclusions Patients with virus detected in BALF were prone to a poorer prognosis. The detection of virus was a high-risk factor of death for LRTI patients. Virus-detected patients required more medical resources.