bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possible impact of plasma oxidation on the structure of the C-terminal domain of SARS-CoV-2 spike protein: a computational study
Authors: Attri Pankaj , Koga Kazunori , Shiratani Masaharu 
Published: December 2020

Abstract
The recent outbreak of a novel coronavirus (SARS-CoV-2) has caused substantial public health issues worldwide. Cold atmospheric plasma (CAP) has shown its potential application in sterilization. It would be interesting to check the possible effect of CAP on the structure of the C-terminal domain of SARS-CoV-2 (SARS-CoV-2-CTD) spike protein and the interaction SARS-CoV-2-CTD with human angiotensin-converting enzyme 2 (hACE2). Therefore, we performed molecular dynamics simulations to calculate the root-mean-square deviation, root-mean-square fluctuation, principal component analysis and solvent-accessible surface area of SARS-CoV-2-CTD and the SARS-CoV-2-CTD/hACE2 complex with and without possible oxidation.
Green Urban Infrastructure: Assessment Challenges
Authors: Kotlyarova S. N. 
Published: December 2020

The presented study addresses the problem of forming and assessing green urban infrastructure, focusing on the elements of green infrastructure in the largest cities of the Russian Federation.Aim. The study aims to analyze approaches to identifying key elements of green infrastructure and methodological approaches to its assessment.Tasks. The authors determine approaches to highlighting key structural elements of green infrastructure; use statistics to comparatively assess the elements of green infrastructure in the largest Russian cities; identify problems in approaches to assessing key elements of green infrastructure.Methods. This study uses the methods of system analysis and comparison to address the problems of assessing key elements of green urban infrastructure and provides data published on the official websites of the constituent entities of the Russian Federation, municipalities, and the Federal State Statistics Service.Results. Key structural elements of green infrastructure are identified and its effects on the urban environment are determined. Methodological approaches to assessing green infrastructure are analyzed, and its key elements in the largest cities of the Russian Federation are comparatively analyzed. The authors identify assessment problems and conclude that it is necessary to update the methodology of approaches to assessing the elements of green infrastructure in order to take into account its results at the stage of urban and spatial planning of territories.Conclusions. The results of the study can be used in developing a methodology for green infrastructure assessment and urban planning.
PEMANFAATAN SARI UBI JALAR UNGU (Ipomoea batatas poiret) SEBAGAI ZAT PEWARNA PADA PEWARNAAN GRAM TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli
Authors: Marbun Rio Wahyu Septian 
Published: December 2020

Ubi jalar ungu (Ipomoea batatas poiret) telah menyebar hampir di seluruh Indonesia dan menunjukkan adanya kandungan senyawa antosianin yang dapat mewarnai bakteri dan pada saat ini, penggunaan zat warna juga dilakukan pada bidang bidang laboratorium mikrobiologi cenderung harganya mahal dan sulitnya mendapatkan pewarna yang digunakan untuk praktikum di laboratorium mikrobiologi Tujuan penelitian adalah untuk mengetahui apakah sari ubi jalar ungu dapat dijadikan sebagai zat warna pada pewarnaan Gram terhadapa bakteri Staphylococcus aureus dan Escherichia coli. Penelitian dilaksanakan menggunakan metode eksperimental laboratory secara in vitro. Hasil penelitian didapatkan bakteri bentuk coccus pada bakteri Staphylococcus aureus dengan warna violet kemerahan pada pewarnaan gram dari kelompok eksperimen yang menggunakan larutan sari ubi jalar sebagai pengganti larutan Gentian Violet dan kelompok kontrol yang menggunakan Larutan Gentian violet. Dan pada bakteri bentuk basil pada Escherichia coli dengan warna merah pada pewarnaan gram dari kelompok eksperimen yang menggunakan larutan sari ubi jalar ungu sebagai pengganti larutan carbol fuchsin. ini membuktikan bahwa air perasan ubi jalar ungu dapat dijadikan sebagai zat warna pada pewarnaan Gram terhadapa bakteri Staphylococcus aureus dan Escherichia coli
REVIEW : PATOGENESIS DAN DIAGNOSA LABORATORIUM DEMAM TIFOID
Authors: Normaidah Id 
Published: December 2020

Demam tifoid disebabkan oleh Salmonella typhi diketahui telah menyebabkan kematian lebih dari 600.000 jiwa di seluruh dunia. Pemahaman terhadap patogenesis dan pemeriksaan laboratorium yang tepat sangat berpengaruh terhadap keberhasilan terapi. Literature review ini bertujuan untuk mengumpulkan pustaka yang berkaitan dengan patogenesis dan pemeriksaan laboratorium pada demam tifoid. Metode literature review ini menggunakan model Sistematic Literature Review (SLR) berdasarkan patogenesis dan pemeriksaan laboratorium. Infeksi S. typhi dimulai dengan masuknya bakteri melalui saluran cerna dan dapat berlangsung hingga 3 minggu. Pemeriksaan laboratorium demam tifoid meliputi kultur bakteri, pemeriksaan serologi, pemeriksaan molekuler, dan pemeriksaan penunjang lainnya. Kultur bakteri merupakan gold standar yang memiliki sensitivitas hingga 80% pada darah. Pemeriksaan serologi dapat dilakukan seperti tes Widal, ELISA, SDS-PAGE blotting, RDT atau POCT menggunakan sampel darah vena, darah kapiler, bahkan serum, serta typhidot, dan Tubex TF. Pemeriksaan penunjang lain dapat ditandai dengan leukositosis dan eosinopenia. Pemeriksaan kimia darah juga didapatkan peningkatan AST dan ALT 2–3 kali lipat nilai normal
ANALISIS KETERLAMBATAN PEMBANGUNAN TOL DENGAN METODE STOKASTIK DAN MITIGASI RISIKO
Authors: Iqbal Muhammad 
Published: December 2020

Berdasarkan informasi dari pihak kontraktor dan pemilik proyek, didapat bahwa Pembangunan Jalan Tol ini mengalami keterlambatan yang signifikan dalam penyelesaiannya. Tujuan dari studi kasus ini adalah untuk mengidentifikasi, menilai, mensimulasikan dan mengurangi risiko keterlambatan Pembangunan Jalan Tol dengan metode Stokastik dan Mitigasi Risiko. Pada kenyataannya ditemukan beberapa artikel keterlambatan proyek jalan tol, tetapi pada studi kasus ini diharapkan dengan mengkombinasikan 2 metode analisis di atas diharapkan dapat memberi masukan baru bagi para peneliti. Hasil mitigasi mengurangi durasi waktu keterlambatan proyek yang relatif maksimal dan sesuai dengan tujuan penelitian. Dari identifikasi risiko, didapat 9 risiko yang berpengaruh terhadap kinerja waktu. Beberapa risiko yang paling besar berpengaruh terhadap kinerja waktu diantaranya : terkait pembebasan lahan, Investigasi tidak memadai sebelum pekerjaan desain dan data survei tidak akurat (pra desain). Analisa risiko terhadap waktu berdasarkan analisa Stokastik didapat bahwa dengan tingkat keyakinan 90% maka kemungkinan proyek dapat diselesaikan dalam waktu diantara 782 - 821 hari, dalam realisasinya proyek Pembangunan Pembangunan Tol ini menghadapi keterlambatan hingga 1112 hari (pobabilitas kejadiannya adalah diatas 95%).
PENANGANAN SIMPANG DI TINJAU DARI ASPEK TEKNIS DAN EKONOMI( study kasus jalan Hr Soebrantas dan jalan Garuda sakti)
Authors: Wakhidho Heru 
Published: December 2020

Kota Pekanbaru yang merupakan pusat regional Riau yang memikul tiga fungsi kegiatan utama, yakni pusat kegiatan pemerintahan, pusat kegiatan perdagangan dan pusat kegiatan transportasi Penelitian ini bertujuan untuk menganalisis tingkat pelayanan simpang berdasarkan data lalu lintas simpang tersebut apakah derajat jenuhnya sudah melewati ambang batas DS = 0,75. Jika nilai DS>0,75, akan dikaji penerapan beberapa alternatif penanganan untuk meningkatkan tingkat pelayanan simpang, untuk kemudian dipilih lagi alternatif terbaik untuk jangka pendek, menengah dan panjang. Metode pengumpulan data yang digunakan dalam penelitian ini adalah metode traffic counting, sedangkan untuk pengkajian alternatif penanganan simpang secara teknik menggunakan metode MKJI 1997, secara ekonomi menggunakan metode LAPI ITB, analisa nilai waktu dengan nilai waktu hasil penelitian Dirjen Bina Marga dan analisa biaya investasi dengan analisa Benefit Cost Ratio dan Net Present Value. Selain itu digunakan juga metode analisa geometrik untuk memproyeksikan jumlah Lalu lintas Harian Rerata (LHR).
Fernandez de Oviedo, historiador y literato. Humanismo, cristianismo e hidalguia
Authors: Kohut Karl 
Published: December 2020

Abstract/Description:
Fernández de Oviedo, famous Spanish conquistador and author of "Historia General y Natural de los Indias", is a controversial historical figure. Since his period, he is usually portrayed negatively as an inhuman, fierce enemy of the Indians. Kohut's monograph investigates the validity of such portrayal. According to his study, his negative role cannot be denied, but there were number of issues that are usually omitted and Oviedo's negative portrayal may have been exaggerated.
Short description written by Michał Gilewski
Reforming the organization’s economic security management process
Authors: Gerasimov Boris 
Published: December 2020

The process of economic security is becoming increasingly important
in the security system of organizations. However, in order to improve the quality and efficiency of this process, changes in the parameters of its functioning
within the organization are sometimes required. The search and study of existing difficulties in the economic security process of the base organization
is carried out. Based on the results of the study, a set of innovative proposals
was identified, and a technology was developed to improve the process of ensuring the economic security of the organization.
Diversification as the main mechanism for ensuring the economic security of enterprises of the Russian military-industrial complex and its regulatory support
Authors: Golubev Sergey 
Published: December 2020

The relevance of the research topic is due to the task set by the President
of the Russian Federation to increase the share of civilian and dual-use products, due to the need to increase the capacity utilization of defense enterprises
in the context of a decrease in the share of the state defense order. The article presents forecasts of options for the production of civil and military products for the medium-term period in terms of the development of the defense
industry, proves the need to develop diversification to ensure the economic
security of defense enterprises, reveals the specifics of the diversification of
defense enterprises, and also considers the issues of making changes to the
resolutions Of the government of the Russian Federation, necessary to intensify work on the diversification of defense enterprises.
Global challenges and the formation of the digital economy: current state, security problems, development trends
Authors: Lytnyeva Natalya , Voronov Sergey , Kidanova Natalia 
Published: December 2020

At present, the issues of economic security seem to be relevant both for
the economic development of the state and for complex scientific research.
A wide range of the vital activities of society includes indicators that reflect
the potential threats that can be encountered by economic agents. The problem of economic security is now becoming increasingly important, and this
in turn is caused by the rapid development of a diversified alternative economy that uses the latest achievements of scientific and technological progress. It is quite difficult to predict the development of the country’s economy
in the long term when the current challenges and threats are not taken into
account. That is why in the information age, where information technology
is the main basis for conducting economic activity, and information security
is one of the main directions of state development, while the state itself
acts as an economic institution. Therefore, the development of the digital
economy in Russia poses both opportunities and significant threats.
Particular types of economic dysfunctions: economic and legal mechanisms of counteraction
Authors: Chebotarev Stanislav , Petryanin Alexey 
Published: December 2020

The article examines the most harmful particular types of economic dysfunctions that significantly undermine the economic security of the Russian Federation. Using the method of deduction and retrospective technique,
their negative impact on the micro- and macroeconomic development of
the national economy is presented. The following forms of economic dysfunctions are proposed for consideration: inflation, dollarization and capital
outflow. Demonstrated are the economic and legal mechanisms of counteracting them, indicating the progressive decriminalization and economic
recovery. New types of economic dysfunctions have been identified that
require a prompt response from the state and bona fide participants in economic relations.
Numerical determination of hydrodynamic characteristics of a submerged airfoil
Authors: Ливеринова М.А. , Тряскин Н.В. 
Published: December 2020

В работе рассмотрено влияние параметров профиля на его гидродинамические характеристики. Задача решена методом, учитывающем вязкость, расчёты произведены в открытом пакете OpenFOAM методом контрольного объема, и потенциальным, численная реализация осуществляется методом граничного элемента. Оценка вихреволнового взаимодействия в потенциальном методе выполняется с помощью распределения гидродинамических особенностей по поверхности профиля и свободной поверхности, и численного решения системы уравнений нелинейной нестационарной задачи о движении крыла вблизи раздела сред вода-воздух. В вязкостном методе совместно решены уравнения Навье-Стокса и неразрывности, осреднённые по Рейнольдсу. Решена плоская задача, движение рассмотрено обращенное. Произведена верификация математической модели и найдено сеточно-независимое решение. Рассмотрено влияние относительной глубины погружения, различных скоростей движения, малых углов атаки, формы профиля в плане на его основные эксплуатационные характеристики: коэффициент подъемной силы и коэффициент сопротивления. Выбраны три профиля в плане: сегментный, Вальхнера, симметричный. Сделаны выводы о влиянии параметров профиля на гидродинамические характеристики (ГДХ), построены зависимости ГДХ от исследуемых параметров и распределение коэффициента давления по поверхности профиля. Рассмотренные методы хорошо согласуются между собой, позволяют оценить ГДХ крыла, построить волновую поверхность, подобрать оптимальные параметры движения для СПК численно на стадии проектирования.
In this article, the influence of the profile parameters on the hydrodynamic characteristics of a submerged airfoil is reviewed. A home-made code based on boundary element method and hypotheses of the potential theory was used. The interaction between free surface and airfoil generated vortexes was estimated by distribution of hydrodynamic singularities on the airfoil and free surface. To consider viscosity effects, an open-source packet OpenFOAM based on finite-volume method was used to solve the Navier-Stokes and continuity equations averaged by Reynolds method. The mathematical model was verified and validated, and a grid-independent solution was found. The influence of the relative depth of immersion, speed, angle of attack, and the shape of the profile on its main hydrodynamic characteristics was considered. Three profiles were selected: segmental, Walchner, and symmetrical. The dependences of coefficients on the studied parameters and the distribution of the pressure coefficient over the profile are studied and analyzed. The considered methods are in a good agreement with each other. Obtained results allow to estimate the wing hydrodynamic characteristics and resulting wave surface which give possibility to select the optimal motion parameters for the hydrofoil at the early design stage.
On the issue of reduction of relative motion of the bow for a ship with energy-saving wing elements in headwind waves
Authors: Хтет З.М. , Рождественский К.В. 
Published: December 2020

В статье рассматривается относительное перемещение носовой оконечности судна с энергосберегающими крыльевыми элементами на встречном волнении, а также результаты сравнения соответствующих расчетных и экспериментальных данных. Метод расчета основан на линейной теории поперечных сечений в частотной области. Сначала производится расчет продольной (вертикальной и килевой) качки судна встречном волнении, а затем расчетные данные используются для расчета относительных перемещений точек корпуса судна. Далее, для найденных численным методом смешанных колебаний носового и кормового крыльев, с привлечением теории Теодорсена колеблющегося профиля. В ходе расчетов демонстрируется влияние на относительное перемещение удлинения и площади энергосберегающих крыльев, а также эффект реализации относительного перемещения и вертикального ускорения при совместном использовании носового и кормового крыльев по сравнению со случаем использования только одного (носового или кормового) крыла. Полученные расчетные данные позволяют получить представление о механизме и эффективности снижения относительного перемещения на встречном волнении при качке судна с энергосберегающими крыльевыми элементами.
Considered in the article are relative vertical displacement of the bow extremity of a ship with energy-saving wing elements in headwind regular waves, and also comparison of corresponding computational and experimental data. The method of calculation is based on a linear strip theory in frequency domain. At first, calculation is carried out of longitudinal (heaving & pitching) motions of a ship with and without wings in headwind waves, and then calculated results are employed to determine relative displacements of ship hull points. To account for the influence of inertial and damping effects of the wings attached to the hull we make use of Theodorsen theory of oscillating foil. Demonstrated in the course of calculations are the effects of wings aspect ratio and area as well as position with respect to the hull (bow wing, stern wing and bow & stern wings). Obtained computed data brings about better understanding of the mechanism and efficiency of reduction of vertical displacements of the hull points for a ship with energy-saving wings in headwind regular waves
Application of data analysis methods to the results of operation of the marine structure health monitoring system
Authors: Коршунов В.А. , Петров О.Н. , Пономарев Д.А. , Родионов А.А. 
Published: December 2020

В работе представлены результаты, анализа и обработки больших массивов данных, получаемых с системы мониторинга состояния МЛСП. Проанализированы зафиксированные внешние воздействия и отклики конструкции с привязкой к временной шкале. Получены коэффициенты корреляции между внешними воздействиями. Построены фазовые портреты внешних воздействий с выраженными аттракторами. Получены коэффициенты корреляции между откликами конструкции. Построены фазовые портреты откликов. Установлены корреляционные зависимости между зафиксированными внешними воздействиями и зарегистрированными откликами конструкции. Проведен кластерный анализ. Установлены связи между кластерами, позволяющие сформулировать гипотезы о более ожидаемых и менее ожидаемых переходах. Определены основные положения для повышения прогнозных характеристик системы мониторинга.
In the paper the results of analysis and processing of large data sets obtained from structures of offshore ice-resistant fixed platform health monitoring system are presented. The fixed external influences and responses of the structure are analyzed with reference to the timeline. Coefficients of correlation between external influences are obtained. Phase portraits of external influences with pronounced attractors are constructed. The coefficients of correlation between the responses of the structure are obtained. Phase portraits of responses were constructed. Correlations between the recorded external influences and the registered responses of the structure have been established. Cluster analysis was carried out. The connections between the clusters have been established, which make it possible to formulate hypotheses about more expected and less expected transitions. The main provisions for improving the predictive characteristics of the monitoring system are determined.
Investigation of iceberg towing processes based on finite-dimensional models of continuous media
Authors: Коршунов В.А. , Мудрик Р.С. , Пономарев Д.А. , Родионов А.А. 
Published: December 2020

В работе рассмотрена проблема управления ледовой обстановкой при освоении участков на морской шельфе. Отмечено, что наиболее эффективным способом управления движения айсбергов и их осколков является использование буксировочных систем. В зависимости от размера айсберга в качестве буксировочной системы может использоваться либо одиночный канат, либо ледовая сетка. Описана технология осуществления буксировки. Рассмотрено два варианта математической формулировки задачи буксировки. Инженерный подход основан на решении системы нелинейных дифференциальных уравнений динамики с известными начальными условиями. Наиболее точным является аппарат механики сплошных сред, который опирается на фундаментальные законы сохранения. Он позволяет построить связанную нелинейную систему дифференциальных уравнений с минимальным количеством допущений. Использование данного подхода возможно при численном моделировании процесса буксировки. В работе создана конечно-элементная модель взаимодействия айсберга с буксировочной системой. Разработан упрощенный алгоритм учета жидкости. Получены кинематические и динамические характеристики процесса буксировки. Определен коэффициент динамичности усилий.
The paper deals with the problem of ice management during the development of the sea shelf. It is noted that the most effective way to control the movement of icebergs and their fragments is to use towing systems. Depending on the size of the iceberg, either a single rope or an ice net can be used as a towing system. The technology of towing is described. Various of the mathematical formulation of the towing problem are considered. The engineering approach is based on solving a system of nonlinear differential equations of dynamics with initial conditions. More accurate approach is the computational continuum mechanics, which is based on fundamental conservation laws. It allows to build a nonlinear system of differential equations with a minimum of assumptions. This approach can be used for numerical modeling of the towing process. In the paper, a finite element model of the interaction of an iceberg with a towing system is created. To account liquid the simplified algorithm is prescribed. The kinematic and dynamic characteristics of the towing process are obtained. The dynamic factor of axial force is determined.