bluuebunny/crossref_metadata_2025_split huggingface dataset:
Codesign and Usability Testing of a Mobile Application to Support Family-Delivered Enteral Tube Care
Authors: Cheng Christie F. , Werner Nicole E. , Doutcheva Nadia , Warner Gemma , Barton Hanna J. , Kelly Michelle M. , Ehlenbach Mary L. , Wagner Teresa , Finesilver Sara , Katz Barbara J. , Nacht Carrie , Coller Ryan J. 
Published: July 2020

BACKGROUND:
Enteral tubes are prevalent among children with medical complexity (CMC), and complications can lead to costly health care use. Our objective was to design and test the usability of a mobile application (app) to support family-delivered enteral tube care.

METHODS:
Human-centered design methods (affinity diagramming, persona development, and software development) were applied with family caregivers of CMC to develop a prototype. During 3 waves of usability testing with design refinement between waves, screen capture software collected user-app interactions and inductive content analysis of narrative feedback identified areas for design improvement. The National Aeronautics and Space Administration Task Load Index and the System Usability Scale quantified mental workload and ease of use.

RESULTS:
Design participants identified core app functions, including displaying care routines, reminders, tracking inventory and health data, caregiver communication, and troubleshooting. Usability testing participants were 80% non-Hispanic white, 28% lived in rural settings, and 20% had not completed high school. Median years providing enteral care was 2 (range 1–14). Design iterations improved app function, simplification, and user experience. The mean System Usability Scale score was 76, indicating above-average usability. National Aeronautics and Space Administration Task Load Index revealed low mental demand, frustration, and effort. All 14 participants reported that they would recommend the app, and that the app would help with organization, communication, and caregiver transitions.

CONCLUSIONS:
Using a human-centered codesign process, we created a highly usable mobile application to support enteral tube caregiving at home. Future work involves evaluating the feasibility of longitudinal use and effectiveness in improving self-efficacy and reduce device complications.
Radial increment in European spruce (Picea abies) as indicator of sanitary condition of spruce forests in the Ukrainian Carpathians
Authors: Prykhodko N. F. , Parpan T. V. , Prykhodko M. M. 
Published: July 2020

In recent years, there has been an intense desiccation of spruce forests in the Ukrainian Carpathians, where European spruce is the main forest-forming species. Over the recent years, desiccation has spread to the spruce forest stands which grow in the Carpathians at the height of over 1,000 m above the sea level. This process causes large economic losses, significant deterioration of the condition and productivity of the forests in the Carpathians, decrease in the level of provision of ecosystemic services by forests, functions they perform, therefore leading to dangerous exogenic processes (floods, freshets, erosion, mudflows, landslides). To determine the interaction between the radial increment and sanitary condition of the spruce stands and substantiate the measures of the use of drying spruce forests, in the Vysokohirsky forestry reserve district of the Ukrainian Carpathians in anti-erosion forests, in hotbeds of desiccation of spruce in 2018, dendrochronological surveys were undertaken in two monitoring plots in forests in weak and severely weakened condition. We collected cores from the model trees, measured width of the annual rings, and developed individual dendrochronologies according to the absolute values of the radial increments and generalized dendrochronologies according to the absolute values of the radial increments and increment indices of the duration of 97 (1921–2017) and 81 years (1937–2017). We conducted single-factor dispersion analysis, calculated the indices of abnormality of the radial increments and correlation coefficient. The results revealed that the lowest increments occurred in the years 1965–1990 in the weakened stand and in 1997–2017 in the severely weakened stand. The relative indices of the forests ranged 83.8–114.6%. The cycles of increment lasted 7–9 years. Over the last few decades, favourable conditions for the growth of the trees took place in 1991–2010, unfavourable in 2011–2017, very unfavourable in 1981–1990. Synchronicity of annual radial increments in the spruces of two monitoring plots equaled 49 years. Correlation coefficient indicates that the type of the conditions of growth location has a significant effect on its variability in the process of trees’ life cycle. Average radial increment of the weakened stand of trees over the last 10 years decreased by 7.9%, while it declined by 54.9% in the severely weakened stand compared with the average increments of the tree stands for the surveyed periods, suggesting that the forests undergo different stages of succession: the weakened stand undergoes the stage of recovery after disturbance, severely weakened forest – stage of disturbance. The studies revealed the dependence of radial increment of spruce on the sanitary condition of the forests. The results of the studies may be used for the assessment of dynamic processes in forest ecosystems as a result of the impact of various factors and planning of the forestry measures.
Burundi Cancer Care Needs: A Call to Action
Authors: Manirakiza Achille Van Christ , Rubagumya Fidel , Ngendahayo Louis 
Published: July 2020

Abstract

Burundi is a landlocked country in the East Central Africa region. Beyond a long civil war strife, cancer care remains overlooked, in terms of both infrastructure and human resources needs, and it shows from estimated global incidence and mortality figures. Through a focused literature search, this study highlights the main cancer care needs in this country, with the aim to gather global oncology support to Burundi.

Implications for Practice
There is little knowledge about the state of oncology in Burundi. This article, based on a literature search, depicts an image of the current state of cancer care in Burundi and aims to compel global health enthusiasts to join in curbing the death toll of cancers in Burundi.
LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments
Authors: Ge Xuhua , Zhang Tao , Yu Xiaoxia , Muwonge Alecia N. , Anandakrishnan Nanditha , Wong Nicholas J. , Haydak Jonathan C. , Reid Jordan M. , Fu Jia , Wong Jenny S. , Bhattacharya Smiti , Cuttitta Christina M. , Zhong Fang , Gordon Ronald E. , Salem Fadi , Janssen William , Hone James C. , Zhang Aihua , Li Hong , He John C. , Gusella G. Luca , Campbell Kirk N. , Azeloglu Evren U. 
Published: July 2020

Significance Statement
The functional basis of the spatial cytoskeletal organization in the kidney podocyte that gives rise to its unique interdigitating morphology has been elusive. An integrative approach identified a novel podocyte-specific actin-associated protein, LIM-nebulette, that brings vimentin intermediate filaments to actin microfilaments, promoting mechanical stability, by regulating focal adhesions, calcium dynamics, and Rho GTPase activity. Silencing of LIM-nebulette is associated with aberrant biophysical properties in human podocytes in culture as well as with multiple glomerulopathies in patients, at both the RNA transcript and protein levels.

Background
Maintenance of the intricate interdigitating morphology of podocytes is crucial for glomerular filtration. One of the key aspects of specialized podocyte morphology is the segregation and organization of distinct cytoskeletal filaments into different subcellular components, for which the exact mechanisms remain poorly understood.

Methods
Cells from rats, mice, and humans were used to describe the cytoskeletal configuration underlying podocyte structure. Screening the time-dependent proteomic changes in the rat puromycin aminonucleoside–induced nephropathy model correlated the actin-binding protein LIM-nebulette strongly with glomerular function. Single-cell RNA sequencing and immunogold labeling were used to determine Nebl expression specificity in podocytes. Automated high-content imaging, super-resolution microscopy, atomic force microscopy (AFM), live-cell imaging of calcium, and measurement of motility and adhesion dynamics characterized the physiologic role of LIM-nebulette in podocytes.

Results

Nebl knockout mice have increased susceptibility to adriamycin-induced nephropathy and display morphologic, cytoskeletal, and focal adhesion abnormalities with altered calcium dynamics, motility, and Rho GTPase activity. LIM-nebulette expression is decreased in diabetic nephropathy and FSGS patients at both the transcript and protein level. In mice, rats, and humans, LIM-nebulette expression is localized to primary, secondary, and tertiary processes of podocytes, where it colocalizes with focal adhesions as well as with vimentin fibers. LIM-nebulette shRNA knockdown in immortalized human podocytes leads to dysregulation of vimentin filament organization and reduced cellular elasticity as measured by AFM indentation.

Conclusions
LIM-nebulette is a multifunctional cytoskeletal protein that is critical in the maintenance of podocyte structural integrity through active reorganization of focal adhesions, the actin cytoskeleton, and intermediate filaments.
Concepções de psicólogas/os dos CRAS de Salvador sobre demanda escolar
Authors: Andrade Thais Fontes , Castelar Marilda , Teles Liliane Alves da Luz 
Published: July 2020

O artigo foca nas concepções de psicólogas/os dos Centros de Referência em Assistência Social de Salvador - Ba que recebem demandas escolares. O estudo faz parte de uma ampla pesquisa de Viégas (2013; 2014; 2016) que identificou a insuficiência de psicólogas/os atuando no campo da educação e encaminhamentos dirigidos a outros serviços públicos que dispõem de atendimento psicológico. O estudo utilizou o método qualitativo, entrevistas semiestruturadas com seis profissionais de psicologia que atuam nos CRAS. As entrevistas foram gravadas em áudio, transcritas e analisadas através da articulação de seus conteúdos com os estudos da educação e a construção do espaço das/os psicólogas/os na assistência social considerando as questões envolvidas nessa política pública. Os resultados apontam a necessidade de ampliação das concepções/visões dos profissionais, da construção de novas referências técnicas e o desenvolvimento de ideias, políticas e estratégias para atuação frente a essas demandas. Tais mudanças nas concepções podem promover melhorias nas suas práticas no atendimento de queixas encaminhadas pelas escolas.
MEASUREMENT OF BODY PARAMETERS UNDER CRITICAL CONDITIONS (SMART SHIRT)
Authors: S. Soundarya M. 
Published: July 2020

This device which we have developed, is a microcontroller based project where we have used GSM & GPS technology and this will be fixed with the soldier and it keeps on monitoring their heart rate, blood pressure, their body temperature and their blood loss. It also tracks their latitude and longitude position by which we get their location. This information’s are send to the control room, where they get the information about all the soldiers and they analyze about the same. When they recognize that there is an emergency they order the rescue team to take up the required steps. By this we are able to recover the injured soldiers and bring them to the military camp to hospitalize them and also to recover the bodies of the dead soldiers.
Intelligent Traffic Control System Using Ad-Hoc Wireless sensor Systems
Authors: Henderson J. Isaac , Aravind M. 
Published: July 2020

This paper deals with designing an automatic traffic control system which works on principle of TRAFFIC DENSITY monitored by Sensors on each side which provides direct information to microcontroller which rerforms decision making to allow traffic based on density. The three density zones are low, medium and high. In each zone an ad hoc sensor is placed. Each sensor will check the presence of the vehicle in the zone using infrared technology and then ad hoc sensor sends the data to master ad hoc. To locate the sensor, each sensor of different zone is addressed by user and that address is fed to the master ad hoc sensor. This master ad hoc sensor will arrange the data from various sensors in an 8 bit data format. It then performs the required processing to determine the green signal time for each side. It has an exceptional system for high priority vehicles like ambulance, as it senses the direction of arrival of these vehicles and gives a green corridor. The main advantage over conventional system is that a side with heavy traffic doesn’t have to wait unreasonably while a side with no/less traffic gets an equal amount of time as that of heavy traffic side which is irascible. This is an improved system based on preference for urgency/density of traffic. This can prove useful in especially Junctions of importance, thereby mediating traffic flow correctly.
α -CONNECTEDNESS BETWEEN SOFT SETS
Authors: Singh Rajput Alpa , S. Thakur S. 
Published: July 2020

Purpose of the study: In the present paper the concept of soft α -connectedness between soft sets in soft topological spaces has been introduced and studied. The notion of connectedness captures the idea of hanging-togetherness of image elements in an object by given a firmness of connectedness to every feasible path between every possible pair of image elements. It is an important tool for the designing of algorithms for image segmentation. The purpose of this paper is to extend the concept of α –connectedness between sets in soft topology.
Main Findings: If a soft topological space (X, τ, E) is soft α -connected between a pair of its soft sets, then it is not necessarily that it is soft α -connected between each pair of its soft sets and so it is not necessarily soft α -connected.
Applications of this study: Image Processing.
Novelty/Originality of this study: Extend of α -connectedness between soft sets in soft topology.
The Person-Centered Care Assessment Tool in Nursing Homes: Psychometric Evaluation of the Italian Version
Authors: Brugnolli Anna , Debiasi Martina , Zenere Alessandra , Zanolin Professor Maria Elisabetta , Baggia Marianna 
Published: July 2020

BackgroundThe Person-centered Care Assessment Tool (P-CAT) was developed as a self-reporting assessment scale for the healthcare staff ratings of the person-centeredness of their nursing practice.AimThis study investigates the psychometric proprieties of P-CAT tool in a sample of staff working in residential units for older people, in the North of Italy.MethodsInternal consistency and reliability were examined using the Cronbach's alpha coefficient. Exploratory factor analysis was used to evaluate construct validity, homogeneity analysis performed to evaluate internal homogeneity of the items and equidistance of item options, test–retest reliability examined by the Pearson correlation coefficient and the intraclass correlation (ICC) coefficient. The P-CAT score was standardized to a 100-point scale, the score differences among groups were compared with one-way ANOVA.ResultsThe exploratory factor analysis supported the construct validity of a two-factor solution. The mean standardized score of P-CAT was 67.3 (SD 12.8) and Cronbach's alpha was .79 for subscale 1 and .75 for subscale 2. The ICC coefficient was .87.ConclusionReliability and homogeneity were satisfactory for the whole P-CAT tool (Cronbach's alpha ≥ .70). Test–retest reliability showed temporal stability of the scale (r Pearson .86, ICC .86). The Italian version of the P-CAT was found to be valid, reliable, and applicable for further research. Two subscales are recommended for the Italian version.
Effect of Rambutan Fruit Peel Extract on Total Sperm Counts of Wistar Rats With Obesity
Authors: Sipahutar Kerin Victoria , Nugraha Yudhi , Fauziah Cut 
Published: July 2020

Obesity caused by a high-fat diet leads to an altered reproductive hormonal profile, including impaired semen quality. Antioxidants can overcome these conditions. One of the well-known sources of antioxidants is in the rambutan fruit peel extract. This research aimed to figure the effect of rambutan fruit peel extract towards total sperm count in Wistar rats induced with high-fat feed. The study design used post-test only control group, subjects were 30 male Wistar rats divided into five groups: Group I (Positive Control) was given high-fat feed, Group II (Treatment Control Group) was given 15mg/kg BW rambutan fruit peel extract, whereas group III, IV, V (Treatment Group) were given an extract of rambutan skin with a dosage of 15, 30, and 60 mg/kg BW, respectively. Treatment was administered for 81 days. This study showed that rambutan fruit peel extract with doses of 15, 30, and 60 mg/kg BW has significantly increased total sperm count in Wistar rats induced with high-fat feed. The outcome using Kruskal Wallis shows a result of p-value 0,010 (CI 95%). Antioxidant compounds found in rambutan fruit peel extract significantly increase total sperm count in Wistar rats induced with high-fat feed, with the highest efficacy on the dose of 15mg/kg BW.

Keywords: Fruit Peel Rambutan Extract; ; ;
Facteurs biologiques des qualités de la viande bovine
Authors: MONIN G. 
Published: July 2020

Les qualités technologiques et sensorielles de la viande bovine que sont l’aptitude à la transformation, le pouvoir de rétention d’eau, la couleur, la tendreté, la jutosité et la flaveur, dépendent de plusieurs facteurs biologiques. Cet article tente de passer en revue les principaux de ces facteurs : la localisation anatomique et la fonction physiologique du muscle, le type génétique (race et type culard), l’âge, le sexe, les conditions d’élevage. Il en ressort que parmi les facteurs de variation des qualités de la viande entre animaux, l’âge, le sexe et les conditions d’élevage jouent un rôle primordial, la race n’ayant qu’un effet mineur.
Les cannes de maïs dans l’alimentation des ruminants. Conservation à l’ammoniac et à l’urée et valeur alimentaire
Authors: CHENOST M. , GAILLARD F. , BESLE J.M. , BOFFETY D. , BOISSAU J.M. , CHAISE J.P. , HETAULT J. , L’HOTELIER L. 
Published: July 2020

On peut conserver sous atmosphère ammoniacale des cannes de maïs pressées en balles le jour même (teneur en matière sèche de 35 à 40 %) ou le lendemain (teneur en MS de 50 %) de la récolte du grain à la moissonneuse-batteuse équipée d’un bec andaineur. Il convient pour cela d’injecter 3 kg d’ammoniac anhydre (dose minimum surtout si les cannes sont humides) soit d’incorporer 6 kg d’urée en granulé (qui s’hydrolyse pour produire 3 kg d’NH3) par 100 kg de MS de cannes. Les balles, traitées quelques heures après leur fabrication et mises sous gaine de plastique pendant 1 mois 1/2 à 2 mois, peuvent alors être ouvertes sans reprise des fermentations. Ces techniques constituent avant tout des traitements conservateurs de produits humides plutôt que des traitements améliorateurs de la valeur alimentaire. La digestibilité et la valeur PDIE des cannes ainsi conservées sont en effet peu modifiées ; la valeur PDIN passe toutefois de 30 à 70 g/kg MS grâce à la fixation de l’ammoniac. Le dispositif d’incorporation directe de l’urée dans la balle reste à perfectionner pour garantir une conservation homogène des cannes à l’intérieur des balles.
Avascular Necrosis of the Humeral Head in a Patient with Methylenetetrahydrofolate Reductase 1 Gene Polymorphism
Authors: Shakir Irshad , Kim Andrew , Salazar Dane 
Published: July 2020

Case:
Atraumatic avascular necrosis (AVN) of the humeral head is a debilitating condition with an insidious onset and progressively worsening pain. We report a case of a woman who presented with left shoulder pain with a medical history of a rare genetic polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene. Advanced imaging demonstrated focal AVN of her humeral head. Treatment varies based on the stage of the disease, which, in this case, included an ultrasound-guided intra-articular corticosteroid injection and oral methylated supplementation.

Conclusion:
In patients with no other known risk factors presenting with AVN of the humeral head, MTHFR polymorphism should be strongly considered a possible cause of AVN.
Intramedullary Cage Removal for a Consolidated Proximal Humerus Fracture
Authors: Nayar Suresh K. , Bansal Ankit , Kreulen R. Timothy , Weiner Scott , Shafiq Babar , Srikumaran Uma 
Published: July 2020

Case:
The expandable intramedullary cage (Conventus Orthopaedics) may treat 3- and 4-part proximal humerus fractures. Cage removal for symptomatic avascular necrosis with humeral head collapse requiring conversion to arthroplasty can be challenging because the cage's collapsing mechanism becomes inoperable after fracture consolidation. We present cage explantation followed by reverse total shoulder prosthesis placement in a 54-year-old man who underwent plate/cage fixation for a 3-part proximal humerus fracture 10 months earlier.

Conclusion:
The proximal humeral cage can be extracted safely while preserving adequate bone stock for subsequent arthroplasty. Additional time and exposure are necessary compared with removing a locking plate alone.
Disability and its prevalence and cause in northwestern Ethiopia: evidence from Dabat district of Amhara National Regional State: A community based cross-sectional study
Authors: Abebe Solomon Mekonnen , Nega Ansha , Gizaw Zemichel , Bayisa Mulugeta , Fasika Solomon , Belay Molalign , Fekadu Abel , Abera Mikyas 
Published: July 2020

Abstract
Background Disability is not just a factor of an individual’s physical condition; it develops through human interactions and reflects the social fabric of communities. Despite the fact that it directly affects 15% of Ethiopians, understanding and policy-relevant studies on disability and the conditions of persons with disabilities are lacking. The Dabat Demographic and Health Surveillance System part of the response to fill this gap. With significant drawbacks in the Surveillance System, this study aimed at assessing the prevalence, types and major causes of disability in Dabat district.Method A community-based cross-sectional study design was employed and covered 17,000 households residing in 13 Kebeles of Dabat district. The district is where DHSS collects health data semi-annually; but this study was designed and executed separately in 2018 utilizing robust tools (World Health Organization’s Disability Assessment Schedule (WHODAS 2.0) used to collect comprehensive data on disability in the district. The data was organized and presented using frequencies and percentages in table and figures. Relevant variables were used to construct a logit model that predicts the likelihood of disability whereby P-value < 0.05 was considered as statistically significant.Results This study found that the overall prevalence of disability in Dabat district was 2.14% [95% CI: 2.03, 2.24]. About 8.3% of households reported at least one member with disability. Visual impairment was the most commonly reported impairment d51%) while 8.19% had multiple impairments. Eighty-three percent of immediate the causes of disability were modifiable – specifically, illness (36.93%), injury (17.81%), and congenital (10.86%). The aged [AOR=1.0; 95% CI: 1.03, 1.04], those unable to read or write illiterate [AOR=1.57; 1.15,2.14], the unmarried/single [AOR=1.39; 95% CI: 185,2.47] and the separated [AOR=2.78; 95% CI: 4.14,6.19] were more likely to risk disability in the population.Conclusion This study reported an increased likelihood of impairment among those with advanced ages. The proportion of households with PwDs was also high. While most disabilities were visual, there were significant numbers with mobility impairments and hard of hearing. Most school-age PwDs did not complete secondary education, while employment was significantly limited. The findings indicated that most causes of disability were reversible.