bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Extracts of Cloves (Syzygium Aromaticum) on Hepatic Cell Damage and Oxidative Stress Caused by Diabetes in Adult Rats
Authors:   Department of Pathology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran., Pourlak Tala , Halimi Monireh ,   Department of Pathology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran., Pourlak Tannaz ,   Aging Research Institute, Tabriz University of Medical Sciences Tabriz, Iran., Maroufi Parham ,   Department of Orthopedics, Shohada Medical Research, School of Medicine, Tabriz University of Medical Sciences,Tabriz, Iran., Ghaderpour Saber ,   Department of Physiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.Student Research Committee, North Khorasan University of Medical Sciences, Bojnord, Iran., Shokoohi Arefeh ,   Student Research Committee, North Khorasan University of Medical Sciences, Bojnord, Iran.
Published: December 2020

Aims: In this study, we investigated the effect of clove extract (Syzygium aromaticum) on liver cell damage and oxidative stress caused by diabetes in adult rats. Methods & Materials: For this study, 28 female rats were collected and divided into four groups: A: Control group; B: Diabetic Control group (DC) which received 20% glycerol dissolved in normal saline as carriers; C: Diabetic rats (DSA) treated with cloves hydroalcoholic extract (4 mg/kg); d) diabetic rats (DG) treated with glibenclamide (5 mg/kg) as a standard drug. Findings: The fasting blood sugar and serum triglyceride levels in the DC group increased significantly compared to the control group (P<0.05). In DC, DG, and DSA groups, high-density lipoprotein, and serum insulin levels decreased significantly compared to the control group (P<0.05). Also, in DG and DSA groups, high-density lipoprotein and serum insulin levels increased significantly compared to the DC group. Conclusion: Cloves can affect fasting blood sugar, serum insulin levels, serum fat profile levels, and prevent liver tissue damage in diabetic rats caused by streptozotocin.
The Effect of 8-Weeks of Low-Intensity Swimming Training on Promyelocytic Leukemia Zinc Finger Protein and Spermatid Transition Nuclear Protein Gene Expression in Azoospermic Rats Model
Authors:   Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran., Zohrabi Karani Leila , Farzanegi Parvin ,   Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran., Azarbayjani Mohammad Ali ,   Department of Exercise Physiology, Tehran Central Branch, Islamic Azad University, Tehran, Iran.
Published: December 2020

Aims: One of the causes of infertility in men is the azoospermia disease, which is attributed to the lack of sperm in each sperm. The primary function of spermatogenesis is the maintenance, proliferation, and differentiation of spermatogonial cells. Thus, the present study aimed to investigate the changes in Promyelocytic Leukemia Zinc Finger (PLZF) and spermatid Transition Nuclear Protein (TNP) gene expression levels in an azoospermic rat model after 8 weeks of low-intensity aerobic training. Methods & Materials: In this experimental study, 15 adult male Wistar rats were randomly divided into three groups of healthy control, with azoospermia, and exercise plus azoospermia after creating an azoospermia model. The patient plus exercise group performed a low-intensity swimming exercise 30 minutes a day, five days a week for 8 weeks, after the creation of the azoospermic rats. A One-way ANOVA test was used for data analysis. Findings: The results showed that a period of swimming exercise program in the exercise plus azoospermia group significantly reduced PLZF gene expression compared to the healthy control groups (P=0.001) and no significant increase to the azoospermia group (P=0.06). There was also a significant decrease in TNP gene expression levels in the exercise plus azoospermia group compared to the healthy control group (P=0.001) and a significant increase in the azoospermia group (P=0.057). Conclusion: Based on these Findings, it can be stated that the alteration of key molecules or signaling pathways and expression of the PLZF and TNP genes in the spermatogenesis process may increase infertility, but regular aerobic exercise, such as low-intensity swimming, helps to control the effects of infertility by increasing the maintenance and development of spermatogonial stem cells.
Lower Extremity Risk Factors in Iranian Adolescent Taekwondo Players
Authors:   Sports Rehabilitation and Health Department, Faculty of Sports Sciences, Shahid Beheshti University, Tehran, Iran., Zarei Mostafa , Johari Kamran ,   Department of Sports Sciences, Islamic Azad University, Bukan Branch, West Azerbaijan, Bukan, Iran., Bagherian Rahim ,   Department of Sports Sciences, Islamic Azad University, Karaj Branch, Karaj, Iran.
Published: December 2020

Purpose: Taekwondo is a martial art and contact sport in which the athletes’ goal is to strike the opponent with maximal force. This fact exposes taekwondo practitioners to the permanent risk of injuries. Therefore, the current prospective study aimed to investigate the internal risk factors of lower extremity injuries in the adolescent male taekwondo players. Methods: In total, 60 adolescent taekwondo players of Iran Premier League voluntarily participated in this research. Before league commencement, navicular drop, Q angle, knee hyperextension angle, the dorsiflexion/plantarflexion range of motion, hamstring flexibility, and their dynamic balance were measured. Then, the injuries of these taekwondo players were recorded during the study time. Results: The injury incidence rate was 7.9 per 1000 hours of exposure (95% confidence interval, 5.33-10.40). The logistic regression analysis data indicated a significant relationship between the Q angle and injuries incidence rate (odds ratio=1.33, P=0.031). The taekwondo players whose Q angles were >14.5 degrees were 1.33 times more prone to lower limb injury. However, no significant relationship was observed between the other risk factors of the study cases and injuries incidence. Conclusion: Regarding the research findings, the Q angle could predict lower limb injuries in the studied taekwondo players. Therefore, it is suggested that this index be considered in the preparticipation evaluation process and preventive strategies.
Effects of a Four-Week Vestibular Exercise Program on Postural Control, Risk of Falling, and Quality of Life in Visually-impaired Individuals
Authors:   Department of Sports Medicine and Health, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran., Mansori Mohammad Hani , Moghadas Tabrizi Yousof ,   Department of Sports Medicine and Health, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran., Karimizadeh Ardakani Mohammad ,   Department of Sports Medicine and Health, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
Published: December 2020

Purpose: Visually-impaired individuals encounter difficulties in balance control and quality of life, and experience more instability, compared to healthy people. Thus, the present study aimed to evaluate the effects of vestibular exercises training program on postural control, risk of falling, and quality of life in individuals with visual impairment. Methods: This was a quasi-experimental study with a pretest-posttest and a control group design. In total, 24 men with visual impairment were randomly divided into the control and experimental groups. The experimental group performed a 4-week vestibular exercise program for 3 weekly sessions of 50 minutes. The Biodex Balance System, Timed Up and Go (TUG) test, and 36-Item Short Form Survey (SF-36) were respectively used to evaluate the postural control, risk of falling, and quality of life of the study samples, before and after the exercise intervention. Univariate analysis and Paired Samples t-test were used to determine the differences between the two groups. Results: The present study results suggested that vestibular exercises improved balance and quality of life, and decrease the risk of falling in visually-impaired people; there was a significant difference between pretest and posttest values in the experimental group. However, no significant difference was observed in the control group in the mentioned variables. The Univariate analysis results revealed that the experimental group obtained higher scores on balance, risk of falling, and quality of life, compared to the control group. Conclusion: Vestibular exercises significantly improved postural control and quality of life, and decreased the risk of falling in the studied samples. It is recommended that these exercises be included in the rehabilitation programs for visually-impaired individuals.
The Effects of 12-Weeks of Sensorimotor Exercise on Pain, Strength, Pelvic Drop, and Dynamic Knee Valgus in Males With Patellofemoral Pain Syndrome
Authors:   Department of Corrective Exercises and Sports Injury, Faculty of Physical Education and Sport Sciences, Bu Ali Sina University, Hamedan, Iran., Yalfani Ali , Ahmadi Mohamadreza ,   Department of Corrective Exercises and Sports Injury, Faculty of Physical Education and Sport Sciences, Bu Ali Sina University, Hamedan, Iran., Gandomi Farzaneh ,   Department of Corrective Exercises and Sports Injury, Faculty of Physical Education and Sport Sciences, Razi University, Kermanshah, Iran.
Published: December 2020

Purpose: Patellofemoral Pain Syndrome (PFPS) is among the most prevalent complaints observed in healthcare clinics. This group of patients encounters Pelvic Drop (PD) and Dynamic Knee Valgus (DNV); its’ causes have been reported as pain and decreased muscle strength. The current study aimed to explore the effects of a 12-week Sensorimotor Exercise (SME) on pain, strength, PD, and DNV in males with PFPS. Methods: This randomized double-blind clinical trial involved 32 patients with PFPS. The study samples were randomly divided into the experimental (n=16) and control (n=16) groups. To assess pain, the Visual Analogue Scale (VAS) was used. Moreover, quadriceps muscle strength was measured by the hip abductor hand dynamometer. To analyze PD and DNV, camera and Kinova software were used during stairs descent. The experimental group performed 12 weeks of SME for 3 one-hour weekly sessions. However, the control group received no therapeutic intervention during this time. The obtained data were analyzed in SPSS using Analysis of Covariance (ANCOVA). Results: The data analysis results suggested that pain significantly reduced in the experimental group, compared to the control group, after twelve weeks of SME (P<0.001). Besides, quadriceps muscle strength (P<0.002) and hip abductor muscle strength (P<0.001) improved, and PD angle (P<0.002) and DNV (P<0.003) were reduced. Conclusion: SME reduced pain and facilitated the frequency and time of muscle activation. It also increased the strength of the gluteus medius muscle as the main stabilizer of the pelvis chain and led to a reduction in PD and DNV. Thus, SME could be used as a comprehensive protocol treatment to improve various disorders in patients with PFPS.
The Effects of a 6-Week Selected Balance and Cawthorne-Cooksey Exercises on Static Balance and Mobility in Female Patients With Multiple Sclerosis
Authors:   Department of Sport Injury and Corrective Exercise, Faculity of Physical Education, Karaj Branch, Islamic Azad University, Alborz, Iran., Feshki Fatemeh , Banaeifar Abdolali ,   Department of Exercise Phisiology, Faculity of Physical Education, Islamic Azad University, South Branch, Tehran, Iran., Kasbparast Mehdi ,   Department of Sport Injury and Corrective Exercise, Faculity of Physical Education, Karaj Branch, Islamic Azad University, Alborz, Iran.
Published: December 2020

Purpose: This quasi-experimental and applied research was conducted in 2019. The statistical population of this study included female patients with Multiple Sclerosis (MS) who were members of the Iranian MS Association. Methods: The study subjects were selected among those with a moderate level of disability (between grades 2 & 5). From the statistical population, initially, 60 individuals were selected by a simple and accessible method; however, for some reason, some samples dropped out during the research. In total, 14, 15, and 19 individuals included the balance, Cawthorne-Cooksey, and control groups, respectively. They were selected based on the study inclusion and exclusion criteria. The three groups were evaluated for static balance by the stork test; then, their mobility was measured by the Timed Up and Go (TUG) test at the pretest phase. Next, the two experimental groups performed the exercises for 6 weeks and 3 sessions per week. Besides, at the end of the exercise protocol, the three groups conducted the mentioned test again at the posttest step. To compare the between-groups data at the posttest, one-way Analysis of Variance (ANOVA) and Least Significant Difference (LSD) test were used to compare the differences between the research groups at a significance level 0.05. Results: The present research results indicated that the balance and Cawthorne-Cooksey exercises performed in the experimental groups revealed statistically significant changes in the two studied factors (both P=0.001). Moreover, the LSD test results signified that in the mobility test, there was a significant difference between the control group and balance exercises group (P=0.001) and the control group and Cawthorne-Cooksey exercises group (P=0.001). Additionally, in the static balance test, a significant difference was observed between the control group and balance exercises group (P=0.003) and the control group and Cawthorne-Cooksey exercises group (P=0.001). Finally, it was revealed that female patients with MS presented better balance and mobility after performing the exercise sessions. Conclusion: The obtained data suggested that specialists could use the explored selected balance exercises and Cawthorne-Cooksey exercises to improve balance and mobility in patients with MS.
Experimental Analysis of Height to Base Length Effect in Trapezoidal Prism Inclined Solar Chimney
Authors: Belhadj Omar , Benzenine Hamidou , Saim Rachid 
Published: December 2020

The use of a solar chimney for ventilation has a very significant environmental and economic impact. The aim of this work is to found the optimum ratio between height and base length in trapezoidal prism-shaped solar chimney. The idea is to give more flexibility to the architectural design in buildings and offer the possibility of combination with other passive or active systems. Trapezoidal shape of solar chimney can be interesting not by increasing the efficiency comparing with other shapes like the rectangular. It may be more aesthetically pleasing, easily to be installed and retrofitted on trapezoidal roofs even on existing buildings. For this reason, three differents ratios of height to base length (h/l = 1), (h/l = 1.5) and (h/l = 2) have been experimentally studied. Two correlations to predict solar chimney exit air velocity and efficiency were developed and tested; good agreement with experimental results is proved. Results show that the flow rate increase by increasing (h/l) in a logarithmic tendency. The optimum thermal efficiency is given where h/l = 1.65. An approach using RETScreen4 software was also carried out and showed that 1 m² solar chimney installed in favorable conditions can cover 37 m² of living space in term of ventilation. For a 120 m² house, solar chimney system saves the equivalent of 23.9 liters of gasoline per year.
Decision-Making for UK Police on the Transportation of Casualties with Life-Threatening Injuries
Authors: Mattock Nicolas 
Published: December 2020

This paper examines the published evidence on police first aid training, the legal context of police first aid and ambulance dispatch, police decision making, provision of pre-hospital care in various models and the transportation of casualties to hospital other than by ambulance. It aims to encourage those involved in police forces’ clinical governance to consider the matter locally and proposes a model that may assist with such consideration and the formulation of policies and procedures if they are deemed necessary.
Implementasi Metode Electre Dalam Menentukan Klasifikasi Hotel
Authors: Asrul Billy Eden William , Zuhriyah Sitti 
Published: December 2020

Lembaga sertifikasi usaha sebagai badan yang berwenang menentukan klasifikasi hotel berdasarkan kelas hotel, bersinergi dengan dinas pariwisata, perhimpunan hotel dan restoran dalam proses audit, pembinaan dan pengawasan. pelaksanaan sertifikasi usaha pariwisata di kota makassar masih perlu ditingkatkan secara efektivitas dan efisiensi, murah, mudah dan cepat. untuk mengatasi masalah tersebut dibuat sebuah sistem pendukung keputusan klasifikasi hotel, sistem ini mengimplementasikan metode Electre dalam mengolah data sehingga mempercepat proses klasifikasi status hotel, memudahkan auditor dalam melakukan proses audit, membantu pelaksanaan pengawasan secara periodik. Metode ELECTRE memberikan keputusan multikriteria dengan konsep outranking perbandingan berpasangan dari alternatif-alternatif berdasarkan kriteria yang sesuai. Hasil uji akurasi dari sistem sebesar 85,71% dengan data uji sebanyak 15 data.
A Systematic Review and Meta-Analysis of Health Utility Estimates in Chronic Spontaneous Urticaria
Authors: Yuan Yan , Xiao Yi , Chen Xiang , Li Jie , Shen Minxue 
Published: December 2020

Background:Chronic spontaneous urticaria (CSU) is a common recurrent skin disease that adversely affect patient's quality of life condition to treat. Economic evaluations of health care often include patient preferences for health outcomes using utilities.Objectives:The study aimed to determine pooled estimates of utility-based quality of life in patients with CSU.Methods:We conducted a systematic review, meta-analysis, and meta-regression of peer-reviewed articles and conference papers that published from database inception to 31 April 2019 that reported utility estimates in patients with CSU. Scores reported with the EQ-5D, SF-6D, SF-12, and SF-36 instruments were converted to utilities using published mapping algorithms. Meta-analysis was used to calculate the pooled and meta-regression was used to examine the effects of possible factors.Results:The pooled utility estimate for CSU was 0.68 [95% confidence interval (CI): 0.67–0.70]. The pooled utility estimate that converted from SF-36 or SF-12 was 0.66 (95% CI: 0.58–0.74), 0.72 (95% CI: 0.70–0.74) for EQ-5D, and 0.65 (95% CI: 0.63–0.67) for SF-6D, respectively. According to the meta-regression, higher proportion of female patients was significantly associated lower utility estimates (p= 0.013).Conclusions:The study provides evidence-based utility estimates to inform health-related burden analysis of CSU and reference for the follow-up cost-effectiveness evaluation of chronic spontaneous urticaria intervention. These results highlight differences in common utility-based instruments and need to be cognizant of the specific instruments used when comparing the results of outcome studies.
D-dimer, Troponin, and Urea Level at Presentation With COVID-19 can Predict ICU Admission: A Single Centered Study
Authors: Hachim Mahmood Y. , Hachim Ibrahim Y. , Naeem Kashif Bin , Hannawi Haifa , Salmi Issa Al , Hannawi Suad 
Published: December 2020

Background: Identifying clinical-features or a scoring-system to predict a benefit from hospital admission for patients with COVID-19 can be of great value for the decision-makers in the health sector. We aimed to identify differences in patients' demographic, clinical, laboratory, and radiological findings of COVID-19 positive cases to develop and validate a diagnostic-model predicting who will develop severe-form and who will need critical-care in the future.Methods: In this observational retrospective study, COVID-19 positive cases (total 417) diagnosed in Al Kuwait Hospital, Dubai, UAE were recruited, and their prognosis in terms of admission to the hospital and the need for intensive care was reviewed until their tests turned negative. Patients were classified according to their clinical state into mild, moderate, severe, and critical. We retrieved all the baseline clinical data, laboratory, and radiological results and used them to identify parameters that can predict admission to the intensive care unit (ICU).Results: Patients with ICU admission showed a distinct clinical, demographic as well as laboratory features when compared to patients who did not need ICU admission. This includes the elder age group, male gender, and presence of comorbidities like diabetes and history of hypertension. ROC and Precision-Recall curves showed that among all variables, D dimers (&gt;1.5 mg/dl), Urea (&gt;6.5 mmol/L), and Troponin (&gt;13.5 ng/ml) could positively predict the admission to ICU in patients with COVID-19. On the other hand, decreased Lymphocyte count and albumin can predict admission to ICU in patients with COVID-19 with acceptable sensitivity (59.32, 95% CI [49.89–68.27]) and specificity (79.31, 95% CI [72.53–85.07]).Conclusion: Using these three predictors with their cut of values can identify patients who are at risk of developing critical COVID-19 and might need aggressive intervention earlier in the course of the disease.
A Comparative Interrupted Times Series on the Health Impact of Probiotic Yogurt Consumption Among School Children From Three to Six Years Old in Southwest Uganda
Authors: Westerik Nieke , Nelson Arinda , Wacoo Alex Paul , Sybesma Wilbert , Kort Remco 
Published: December 2020

Introduction: Following a school milk feeding program in Southwest Uganda, we initiated a probiotic yogurt school feeding program in the same region in 2018. In order to investigate the potential health benefits from probiotic yogurt we conducted an observational study, where we compared the effect of the consumption of locally produced probiotic yogurt containing Lactobacillus rhamnosus yoba 2012 to milk in pre-primary schoolchildren from different schools on the occurrence of respiratory tract infections (common cold) and skin infections (e.g., tinea capitis).Method: A comparative interrupted time series over a period of 3 weeks of baseline followed by 9 weeks of 100 ml of probiotic yogurt or milk consumption for 5 days per week. In total 584 children attending five different schools were followed during consumption of probiotic yogurt and 532 children attending five other schools during consumption of milk. Incidences of respiratory tract infection symptoms and skin infection symptoms, changes in anthropometric indicators and absenteeism were recorded.Results: Over the course of the study period the incidence rate for common cold symptoms decreased faster in the yogurt group than in the milk group (p = 0.09) resulting in a final RR of 0.85 (95% CI: 0.5–1.4) at the end of the observational period. The incidence rate of skin infection related symptoms also reduced faster in the yogurt group compared to the milk group (p &lt; 0.0001) resulting in a relative risk factor (RR) of 0.6 (CI: 0.4–0.9) at the end of the observational period. Anthropometric indicators and level of absenteeism did not show significant differences between yogurt and milk.Conclusion: Notwithstanding the observed positive trend and effect of probiotic yogurt on the incidences of common cold and skin infections, respectively, we consider the results of this comparative interrupted time series inconclusive due to differences in the recorded health parameters between the probiotic yogurt and milk control groups at base line, and fluctuations over the course of the intervention period. An improved study design, with more uniform study groups, a longer intervention period and a third control group without yogurt or milk is required to draw definitive conclusions.