bluuebunny/crossref_metadata_2025_split huggingface dataset:
QUALIDADE VOCAL DOS PROFESSORES DE UMA UNIVERSIDADE PÚBLICA EM BELÉM, PARÁ
Authors: Ferreira e Silva Luigi , Mauro Neto Heraldo Hebert , Nascimento Batista Igor , Castro Veloso José de Ribamar , Palheta Neto Francisco Xavier 
Published: December 2019

Objetivo: avaliar a prevalência de distúrbios vocais em professores dos Campi de uma universidade pública em Belém, Pará. Método: estudo prospectivo, transversal e descritivo, o qual envolveu 188 docentes entrevistados por meio de um questionário autoaplicável acerca da qualidade de voz, no período de abril de 2014 a março de 2015. Resultados: dos sintomas questionados: 99 (53,2%) referiram irritação na garganta; 77 (40,9%) relataram pigarro; 75 (33,9%) queixaram-se de rouquidão; e 48 (25,5%) disseram ter sensação de corpo estranho na garganta. Dos fatores de risco: apenas 24 (12,8%) eram tabagistas; 130 (69,1%) trabalhavam até 40 horas/semana; 162 (86,2%) lidavam com no máximo 40 alunos/sala. Dos fatores de proteção: 113 (60,1%) praticavam atividade física; 79 (42%) receberam orientações de proteção laboral; 63 (33,5%) realizavam algum cuidado especial com a voz; 80 (42,5%) relataram ingerir água adequadamente. Conclusão: houve baixa prevalência de distúrbios vocais, sendo a irritação na garganta o sintoma mais referido. Evidenciou-se correlação estatisticamente significante entre a prática de exercício físico, como fator de proteção, e a sensação de corpo estranho na garganta, assim como, entre a prática de cuidados especiais, como fator de risco, e a rouquidão. Ressalta-se a necessidade de assistência multiprofissional para o correto exercício da docência. Descritores: medicina do trabalho; disfonia; docência; qualidade de vida; otorrinolaringologia.
AVALIAÇÃO DO ÍNDICE DE PLACA VISÍVEL ANTES E DEPOIS DE SESSÕES DE EDUCAÇÃO EM SAÚDE BUCAL COM CRIANÇAS
Authors: Oliveira Marcia de Freitas , Zanchett Sarita , Candido Oliveira Andryu Weslley 
Published: December 2019

Introdução: A manutenção de uma boa saúde bucal está diretamente relacionada com a habilidade de um indivíduo controlar a placa bacteriana. Projetos de educação em saúde, principalmente em escolares, tem proporcionado o desenvolvimento de melhores técnicas de escovação e uso de fio dental, tão importantes para dentes hígidos. Objetivo: O objetivo deste trabalho foi avaliar o índice de placa bacteriana em escolares antes e após sessões de educação em saúde bucal na EBM Conselheiro Mafra, Blumenau SC dentro do projeto “FURBmóvel é Saúde e Mais Educação”. Materiais e métodos: Foi realizado um levantamento do índice de cárie através do índice de dentes decíduos cariados, extraídos ou obturados (CEO) e do índice de dentes permanentes cariados, perdidos ou obturados (CPOD. Realizou-se também a evidenciação de placa bacteriana e foi anotado o índice de higiene oral simplificado (IHOS). Resultados: Após 4 semanas de educação em saúde bucal, foi realizado novamente o índice de Higiene Oral Simplificado (IHOS). Este trabalho incluiu 44 escolares com média de idade de 5,81 anos. O índice de ceo médio foi 2,54. O índice CPO-D médio foi 0,09. O IHOS médio inicial foi 2,09 e o IHOS médio final foi 1,79. Essa diferença foi significativa segundo o teste t de Student (p=0,0203). Conclusão: Este trabalho mostrou a eficácia quanto a redução do índice de placa bacteriana em escolares após 4 sessões de educação em saúde bucal.
Reverse-strip-structure Ge28Sb12Se60 chalcogenide glass waveguides prepared by micro-trench filling and lift-off
Authors: Li Chengdong , Guo Panpan , Huang Wei , Zhang Wei , Xu Peipeng , Zhang Peiqing 
Published: December 2019

We propose a reverse-strip-structure chalcogenide

G
e

28

S
b

12

S
e

60

glass waveguide prepared through micro-trench filling and lift-off technique. This fabrication method avoids processes that are directly applied to chalcogenide glass films, such as photolithography and dry etching, thereby yielding waveguides with excellent surface profiles. The nonlinear refractive index (

n
2

), nonlinear absorption coefficient (

β

), and third-order nonlinear susceptibility (

χ
3

) of the

G
e

28

S
b

12

S
e

60

glass films are estimated by

Z

-scan technique, and excellent nonlinearities were observed. The linear optical losses of the as-prepared waveguide samples with a cross-sectional area of

3.0

µ

m

×

1.0

µ

m

and

5.0

µ

m

×

1.0

µ

m

are measured and calculated to be 2.2 and 1.7 dB/cm at 1550 nm, respectively, using the lensed fiber and cut-back method. This study predicts that reverse-strip-structure waveguides based on micro-trench filling and lift-off technique are promising candidates for high-quality on-chip integrated nonlinear optical devices and warrant further research.
Clinical Massively Parallel Sequencing
Authors: Gao Ge , Smith David I 
Published: December 2019

Abstract

BACKGROUND
The newest advances in DNA sequencing are based on technologies that perform massively parallel sequencing (MPS). Since 2006, the output from MPS platforms has increased from 20 Mb to &gt;7 Tb. First-generation MPS platforms amplify individual DNA molecules to multiple copies and then interrogate the sequence of those molecules. Second-generation MPS analyzes single unamplified molecules to generate much longer sequence reads but with less output than first-generation MPS and lower first-pass accuracy. With MPS technologies, it is now possible to analyze genomes, exomes, a defined subset of genes, transcriptomes, and even methylation across the genome. These technologies have and will continue to completely transform the clinical practice.

CONTENT
The major first- and second-generation MPS platforms and how they are used in clinical practice are discussed.

SUMMARY
The ability to sequence terabases of DNA per run on an MPS platform will dramatically change how DNA sequencing is used in clinical practice. Currently, MPS of targeted gene panels is the most common use of this technology clinically, but as the cost for genome sequencing inches downward to $100, this may soon become the method of choice (with the caveat that, at least in the near term, clinical-grade genome sequencing with interpretation may cost much more than $100). Other uses of this technology include sequencing of a mixture of bacterial and viral species (metagenomics), as well as the characterization of methylation across the genome.
Urothelial Carcinoma Detection Based on Copy Number Profiles of Urinary Cell-Free DNA by Shallow Whole-Genome Sequencing
Authors: Ge Guangzhe , Peng Ding , Guan Bao , Zhou Yuanyuan , Gong Yanqing , Shi Yue , Hao Xueyu , Xu Zhengzheng , Qi Jie , Lu Huan , Zhang Xiaoyun , Zhan Yonghao , Li Yifan , Wu Yucai , Ding Guangpu , Shen Qi , He Qun , Li Xuesong , Zhou Liqun , Ci Weimin 
Published: December 2019

AbstractBACKGROUNDCurrent noninvasive assays for urothelial carcinoma (UC) lack clinical sensitivity and specificity. Given the utility of plasma cell-free DNA (cfDNA) biomarkers, the development of urinary cfDNA biomarkers may improve the diagnostic sensitivity.METHODSWe assessed copy number alterations (CNAs) by shallow genome-wide sequencing of urinary cfDNA in 95 cancer-free individuals and 65 patients with UC, 58 with kidney cancer, and 45 with prostate cancer. We used a support vector machine to develop a diagnostic classifier based on CNA profiles to detect UC (UCdetector). The model was further validated in an independent cohort (52 patients). Genome sequencing data of tumor specimens from 90 upper tract urothelial cancers (UTUCs) and CNA data for 410 urothelial carcinomas of bladder (UCBs) from The Cancer Genome Atlas were used to validate the classifier. Genome sequencing data for urine sediment from 32 patients with UC were compared with cfDNA. To monitor the treatment efficacy, we collected cfDNA from 7 posttreatment patients.RESULTSUrinary cfDNA was a more sensitive alternative to urinary sediment. The UCdetector could detect UC at a median clinical sensitivity of 86.5% and specificity of 94.7%. UCdetector performed well in an independent validation data set. Notably, the CNA features selected by UCdetector were specific markers for both UTUC and UCB. Moreover, CNA changes in cfDNA were consistent with the treatment effects. Meanwhile, the same strategy could localize genitourinary cancers to tissue of origin in 70.1% of patients.CONCLUSIONSOur findings underscore the potential utility of urinary cfDNA CNA profiles as a basis for noninvasive UC detection and surveillance.
Spontaneous Rupture of an Esophageal Mucocele Into the Airway
Authors: Manoharan Dinesh , Srivastava Deep Narayan , Madhusudhan Kumble Seetharama 
Published: December 2019

ABSTRACT
An esophageal mucocele is an uncommon complication after exclusion surgery of the thoracic esophagus. Although asymptomatic in most cases, it can progressively enlarge in size to cause symptoms requiring intervention. Occasionally, spontaneous decompression of its contents into the neck, mediastinum, peritoneal cavity, or tracheobronchial tree can occur, leading to potentially serious complications. We present a case of symptomatic esophageal mucocele after esophageal exclusion, complicated by the formation of an esophagobronchial fistula.
Tatalaksana Perioperatif Ventilasi Mekanik pada Pasien dengan Gagal Jantung Kiri
Authors: Nugroho Budi , Hadinata Yudi 
Published: December 2019

Penyakit gagal jantung merupakan suatu kondisi kelainan pada pasien dimana kemampuan pengisian dan fungsi pompa jantung mengalami gangguan. Gagal jantung sendiri dapat terjadi secara akut atau kronis serta berpotensi mengancam jiwa. Ketika kondisi tersebut memburuk maka dapat menyebabkan gangguan fungsi pernapasan dan perburukan kondisi hingga berakibat kematian. Kondisi gagal jantung dapat terjadi selama tindakan perawatan perioperatif pembedahan yang membutuhkan terapi farmakologi dan terapi non farmakologi. Salah satu modalitas terapi non farmakologi yang dapat membantu fungsi pompa jantung dalam kondisi gagal jantung adalah ventilasi mekanik. Tinjauan pustaka ini akan mengulas tentang terapi perioperatif ventilasi mekanik pada pasien dengan gagal jantung.
Wohin mit der digitalen Edition?
Authors: Fritze Christiane 
Published: December 2019

Zusammenfassung
Editionen bieten verschiedenen geisteswissenschaftlichen Fächern die Grundlage für weitere Forschungen. Mit der Digitalisierung erleben die Editionswissenschaften zunehmend projektbasiert und drittmittelgefördert eine Renaissance. Problematisch bleibt die Frage, wohin mit der Edition nach Projektende? Schon von Beginn an sollten Bibliotheken mit den ihnen eigenen Services und Kompetenzen ernstzunehmende Partner sein, müssten sich allerdings der Aufgabe v. a. in finanzieller Hinsicht stellen.
Bewegung am Lernort: Ein stromerzeugendes Fahrradergometer in der Philologischen Bibliothek der Freien Universität Berlin
Authors: Wagner Janet 
Published: December 2019

Zusammenfassung
Bewegungsfördernde Geräte wie Laufband, Schreibtischfahrrad oder stromerzeugende Räder können vor, während oder nach intensiven Lernphasen genutzt werden, um Konzentration zu steigern, sich zu bewegen und eine stimulierende Lernumgebung in der Bibliothek schaffen.
Der Lernort Bibliothek ist bedeutsam für das Lernen, die Lehre und die Forschung. Neben moderner Infrastruktur und bequemen, flexiblem Raummobiliar können bewegungsfördernde Geräte am Lernort Motivation & Bewegung für die Studierenden bewirken. In einer mehrwöchigen Teststellung mit verschiedenen Standorten wurde ein stromerzeugendes Fahrrad in der Philologischen Bibliothek aufgestellt.
All you can read – Ein ambitioniertes Leseprojekt
Authors: Santner Nina , Sigg Melanie 
Published: December 2019

Zusammenfassung
Im Projekt Lesejahr.ch lesen Schüler und Lehrer an Schweizer Mittelschulen um die Wette. Sie können dabei entweder viel lesen oder schlau lesen, damit punkten und Preise gewinnen. Das Projekt der schulinternen Mediotheken macht das Lesen cool und sichtbar. Denn Lesefreude und Orientierung in der Medienwelt sind in Zeiten von Twitter und Instagram nach wie vor wichtige Ziele für anspruchsvolle Schulen.
Insight into the atomic scale structure of CaF2-CaO-SiO2 glasses using a combination of neutron diffraction, 29Si solid state NMR, high energy X-ray diffraction, FTIR, and XPS
Authors: Chungong Louis Forto , Isaacs Mark A. , Morrell Alexander P. , Swansbury Laura A. , Hannon Alex C. , Lee Adam F. , Mountjoy Gavin , Martin Richard A. 
Published: December 2019

Abstract
Bioactive glasses are important for biomedical and dental applications. The controlled release of key ions, which elicit favourable biological responses, is known to be the first key step in the bioactivity of these materials. Properties such as bioactivity and solubility can be tailored for specific applications. The addition of fluoride ions is particularly interesting for dental applications as it promotes the formation of fluoro-apatite. To date there have been mixed reports in the literature on how fluorine is structurally incorporated into bioactive glasses. To optimize the design and subsequent bioactivity of these glasses, it is important to understand the connections between the glass composition, structure and relevant macroscopic properties such as apatite formation and glass degradation in aqueous media. Using neutron diffraction, high energy X-ray diffraction, 29Si NMR, FTIR and XPS we have investigated the atomic scale structure of mixed calcium oxide / calcium fluoride silicate based bioactive glasses. No evidence of direct Si-F bonding was observed, instead fluorine was found to bond directly to calcium resulting in mixed oxygen/fluoride polyhedra. It was therefore concluded that the addition of fluorine does not depolymerise the silicate network and that the widely used network connectivity models are valid in these oxyfluoride systems.
Realisation and assessment of a low-cost LED device for contact lens disinfection by visible violet light
Authors: Hoenes Katharina , Wenzel Ulla , Hessling Martin 
Published: December 2019

Abstract
This study presents a device for efficient, low-cost and eye-friendly overnight disinfection of contact lenses by visible violet light as an alternative to disinfection with biocide-containing solutions. Bacterial solutions with one Pseudomonas and one Staphylococcus strain each were irradiated for up to 8 h in commercial transparent contact lens cases by the presented light-emitting diode (LED) device. Samples were taken at different intervals and distributed on agar plates. The surviving bacteria were determined by counting of colony-forming units and compared to the specific requirements of the stand-alone test for contact lens disinfection of the hygiene standard ISO 14729. The concentration of both microorganisms was reduced by three orders of magnitude after less than 4 h of irradiation. The LED current and intensity have not yet been at maximum and could be further increased if necessary for other microorganisms. The presented device fulfils the requirement of the stand-alone test of the contact lens hygienic standard ISO 14729 for the tested Pseudomonas and Staphylococcus strains. According to literature data, the inactivation of Serratia marcescens, Candida albicans and Fusarium solani seems also possible, but may require increased LED current and intensity.
Evidence in obese children: contribution of tri-ponderal mass index or body mass index to dyslipidemia, obesity-inflammation, and insulin sensitivity
Authors: Akcan Nese , Obaid Moaaz , Salem Jana , Bundak Ruveyde 
Published: December 2019

Abstract

Background
Chronic inflammation plays a critical role in the development of obesity-related metabolic dysfunction. The tri-ponderal mass index (TMI) may be more effective than body mass index (BMI) for estimating body fat levels. This study compared the efficacy of BMI and TMI in screening for dyslipidemia, insulin sensitivity, and inflammation in childhood obesity.

Methods
This study included 80 children who were classified as normal weight, overweight or obese using standardized BMI (BMI standard deviation score [SDS]) and TMI measurements. Fasting blood glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), triglycerides, total cholesterol, liver function enzymes, leptin, serum free fatty acid (FFA), fetuin-A, monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF-α), and interleukin (IL)-6 levels were evaluated using both classification systems.

Results
LDL-C levels significantly differed within the groups by BMI, and serum FFA levels differed only according to the TMI. Serum MCP-1, TNF-α, IL-6, and fetuin-A levels showed no difference according to the TMI or BMI SDS. Fetuin-A levels did not differ between the insulin-resistant and non-resistant cases. Fetuin-A was the only inflammatory marker positively correlated with BMI. No inflammatory markers correlated with TMI. Fetuin-A, MCP-1, TNF-α, and IL-6 correlated with each other, but not with metabolic parameters.

Conclusions
BMI SDS and TMI were associated with metabolic disturbances in childhood obesity. Weight versus heightn values may be related more to metabolic parameters than to inflammatory changes.
Circular dichroism mode splitting and bounds to its enhancement with cavity-plasmon-polaritons
Authors: Baranov Denis G. , Munkhbat Battulga , Länk Nils Odebo , Verre Ruggero , Käll Mikael , Shegai Timur 
Published: December 2019

Abstract
Geometrical chirality is a widespread phenomenon that has fundamental implications for discriminating enantiomers of biomolecules. In order to enhance the chiral response of the medium, it has been suggested to couple chiral molecules to resonant optical cavities in order to enhance the circular dichroism (CD) signal at the resonant frequency of the cavity. Here, we studied a distinctly different regime of chiral light-matter interaction, wherein the CD signal of a chiral medium splits into polaritonic modes by reaching the strong coupling regime with an optical microcavity. Specifically, we show that by strongly coupling chiral plasmonic nanoparticles to a non-chiral Fabry-Pérot microcavity one can imprint the mode splitting on the CD spectrum of the coupled system and thereby effectively shift the initial chiral resonance to a different energy. We first examined the effect with the use of analytical transfer-matrix method as well as numerical finite-difference time-domain (FDTD) simulations. Furthermore, we confirmed the validity of theoretical predictions in a proof-of-principle experiment involving chiral plasmonic nanoparticles coupled to a Fabry-Pérot microcavity.
1997 and 2016: Referenda, Brexit, and (Re-)bordering at the European Periphery
Authors: Goodwin-Hawkins Bryonny , Dafydd Jones Rhys 
Published: December 2019

Abstract
2016 is likely to be recalled – in Europe, at least – as a temporal bordering, after a majority in the United Kingdom voted to leave the European Union. The “Brexit” referendum result has been pinned on the rise of populist politics and the revenge of so-called “left behind” places. Regardless of reasons, the referendum left the UK with fraught politics and protracted negotiations, especially over how to re-border with a Europe that has held the dismantling of borders at the heart of its philosophical project. While Brexit has already become a byword, an earlier referendum on British borders has long slipped from international note. In 1997, a majority in Wales (one of the four constituent countries of the UK), voted for devolution from central government in Westminster. Like the Brexit referendum twenty years later, the majority in favor of devolution was slight, exposing uneasy fractures and internal cleavages as it opened fresh questions of governance and geography. By attending to a small country at the periphery of Europe, we seek to destabilize the assumption of shared markers of global bordering (1989, 2001), revealing instead the palimpsests of identity and territoriality across which re-made borders run “all over.”
Health of the offspring of immigrants: the BaBi birth cohort study
Authors: Miani Céline , Razum Oliver , Spallek Jacob 
Published: December 2019

Abstract
Children with a migration background are more at risk of health-related problems than those without a migration background. The German health system still does not adequately meet the challenges of on increasingly heterogeneous population, not least due to a lack of adequate epidemiological data and models. The BaBi study contributes to gaining new insights in the development of health inequalities due to cultural diversity in Germany, with a focus on pregnancy and early childhood.
Psychische Gesundheit von Kindern und Jugendlichen in Deutschland: Aktuelle Häufigkeiten und zeitliche Trends. Ergebnisse aus der KiGGS-Langzeitstudie
Authors: Schlack Robert , Baumgarten Franz , Hölling Heike 
Published: December 2019

Zusammenfassung
Aktuelle Zahlen zur psychischen Gesundheit von Kindern und Jugendlichen in Deutschland stehen seit kurzer Zeit aus der zweiten Folgeerhebung der KiGGS-Langzeitstudie (KiGGS Welle 2) zur Verfügung. Dabei zeichnet sich ein leichter Rückgang der Häufigkeiten psychischer Auffälligkeiten und diagnostizierter ADHS ab, der vor allem Jungen in unterschiedlichen Altersbereichen betrifft. Nach wie vor sind psychische Auffälligkeiten mit Beeinträchtigungen der gesundheitsbezogenen Lebensqualität assoziiert.
Einfluss von Sport und Bewegung auf Kinderfüße
Authors: Müller Steffen , Müller Juliane 
Published: December 2019

Zusammenfassung
Kinderfüße zeigen typische Unterschiede in der Morphologie und Funktion im Vergleich zu Erwachsenen. Was sind Besonderheiten der kindlichen Fußstruktur? Welche Belastungen wirken bei Spiel und Bewegung? Welchen Einfluss hat körperliche und sportliche Aktivität? Besteht ein Zusammenhang zw. der Kraft und motorischen Funktion der Füße? Welchen Einfluss hat Übergewicht auf die kindliche Fußentwicklung? Antworten darauf soll diese Übersichtsarbeit geben.
Der Kinder- und Jugendreport der DAK-Gesundheit: Eine neue Datengrundlage für die pädiatrische Gesundheitsforschung
Authors: Witte Julian , Batram Manuel , Greiner Wolfgang 
Published: December 2019

Zusammenfassung
Die systematische Beschreibung der gesundheitlichen Lage von Kindern und Jugendlichen sowie die Analyse beeinflussender Faktoren ist von hoher Public Health-Relevanz. Neben primären Befragungsdaten stehen hierzu vermehrt Abrechnungsdaten der Gesetzlichen Krankenversicherung im Mittelpunkt des Interesses. Der Kinder- und Jugendreport der DAK-Gesundheit als kumulierte Quer- und Längsschnittanalyse konzipierte Reportreihe zeigt dabei das Potential einer auf beiden Datenquellen basierenden Versorgungsforschung auf.
Das Sozialpädiatrische Kita-Konzept: ein interdisziplinärer Ansatz
Authors: Bantel Susanne , Jones Emely , Walter Ulla , Wünsch Andrea 
Published: December 2019

ZusammenfassungDie Schuleingangsdaten in der Region Hannover verweisen auf vermehrte Entwicklungsdefizite bei Kindern aus bildungsfernen und sozial benachteiligten Familien. Vor diesem Hintergrund wurde ein interdisziplinäres Konzept zur Entwicklungsförderung von Kindern in Kindertageseinrichtungen (Kitas) als Baustein der Frühen Hilfen – Frühen Chancen der Region Hannover entwickelt. Das Konzept zeigt, wie eine Vernetzung von Akteuren und damit eine frühzeitige Förderung von Kindern gelingen kann.
Die Rolle von sozialem Kapital in der Gesundheitsentwicklung von Kindern
Authors: Klocke Andreas , Stadtmüller Sven 
Published: December 2019

Zusammenfassung
Der Beitrag untersucht die Auswirkungen von Sozialkapital auf die Gesundheit und das Gesundheitsverhalten von Kindern. Die verwendeten Daten stammen aus der Panelstudie Gesundheitsverhalten und Unfallgeschehen im Schulalter (Laufzeit 2013–2020, mit n≈10.000 pro Welle). Wir betrachten Veränderungen im Volumen des Sozialkapitals zwischen der ersten und zweiten Erhebungswelle auf die Ausprägung der Gesundheitsvariablen in der dritten Erhebungswelle. Die Ergebnisse lassen auf einen kausalen Einfluss des Sozialkapitals auf die Gesundheit und auf das Gesundheitsverhalten der Kinder schließen.