bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Wheat GENIE3 Network Provides Biologically-Relevant Information in Polyploid Wheat
Authors: Harrington Sophie A , Backhaus Anna E , Singh Ajit , Hassani-Pak Keywan , Uauy Cristobal 
Published: August 2020

AbstractGene regulatory networks are powerful tools which facilitate hypothesis generation and candidate gene discovery. However, the extent to which the network predictions are biologically relevant is often unclear. Recently a GENIE3 network which predicted targets of wheat transcription factors was produced. Here we used an independent RNA-Seq dataset to test the predictions of the wheat GENIE3 network for the senescence-regulating transcription factor NAM-A1 (TraesCS6A02G108300). We re-analyzed the RNA-Seq data against the RefSeqv1.0 genome and identified a set of differentially expressed genes (DEGs) between the wild-type and nam-a1 mutant which recapitulated the known role of NAM-A1 in senescence and nutrient remobilisation. We found that the GENIE3-predicted target genes of NAM-A1 overlap significantly with the DEGs, more than would be expected by chance. Based on high levels of overlap between GENIE3-predicted target genes and the DEGs, we identified candidate senescence regulators. We then explored genome-wide trends in the network related to polyploidy and found that only homeologous transcription factors are likely to share predicted targets in common. However, homeologs which vary in expression levels across tissues are less likely to share predicted targets than those that do not, suggesting that they may be more likely to act in distinct pathways. This work demonstrates that the wheat GENIE3 network can provide biologically-relevant predictions of transcription factor targets, which can be used for candidate gene prediction and for global analyses of transcription factor function. The GENIE3 network has now been integrated into the KnetMiner web application, facilitating its use in future studies.
Localismo, desempenho institucional e (in)justiça territorial
Authors: Martins da Fonseca Antonio Angelo 
Published: August 2020

A emergência de localismos no contexto do federalismo brasileiro estimula o debate recente sobre justiça territorial na geografia. O objetivo deste artigo é contribuir nesse debate analisando comparativamente o desempenho institucional dos 81 municípios do Estado da Bahia, Brasil, emancipados desde a década de 1980, conforme com o Índice de Desempenho de Gestão do Território (IGT) e com o quadro tipológico constituído por 20 tipos de serviços, oriundos de indicadores sociais, econômicos, gerenciais e de infraestrutura. Os procedimentos metodológicos para a elaboração e cálculo do igt envolveram o levantamento de dados secundários em torno dos indicadores relacionados: a) aos instrumentos de planejamento, regulação e gestão; b) a descentralização política; c) e a justiça e segurança pública. Para o quadro tipológico, os procedimentos envolveram trabalhos de campo e a realização de 112 entrevistas semiestruturadas com 16 lideranças de cada município. Os resultados apontaram que os novos municípios emancipados vêm evoluindo em termos sociais, participativos e gerenciais. Porém, ainda apresentam conteúdos de injustiças territoriais devido às carências de serviços essenciais como rede de esgotos, segurança, lazer e assistência jurídica. A conclusão que se chegou é que as injustiças territoriais são, de fato, os conteúdos mais representativos dos localismos no Estado da Bahia.Ideias destacadas: artigo de pesquisa sobre como as emancipações de municípios são exemplos de ações localistas. Os localismos expressam a densidade de justiça territorial dos municípios. O Índice de Desempenho de Gestão do Território (IGT) revela a (in)justiça territorial. Os novos municípios apresentam (in)justiça territorial.
Fixos e fluxos: revisitando um par conceitual
Authors: Barros José D'Assunção 
Published: August 2020

O artigo propõe revisar e discutir o par conceitual “fluxos e fixos” proposto pelo geógrafo brasileiro Milton Santos nos anos 1970, ampliando um quadro de exemplos pertinentes e produzindo um esquema compreensivo válido para este sistema conceitual. O uso desse par conceitual na Geografia e em outras áreas das Ciências Humanas é ainda pertinente na atualidade, pois permite apreender tanto as estruturas como o movimento de uma cena geográfica. Em vista disto, retomar o conceito e ampliar suas possibilidades e campos de aplicação torna-se relevante. Em uma sessão inicial, comenta-se a importante percepção de que o espaço contém tempo, encaminhada por geógrafos do início do século XX, como Vidal de La Blache. Entrementes, sustenta-se que, se foi uma contribuição vital a percepção do tempo acumulado no espaço geográfico, é preciso também dar a perceber que o tempo também está presente nas paisagens geográficas pelo simples fato de que estas não são estáticas, aspecto contemplado pela complementaridade recíproca do par conceitual fixos-fluxos.Ideias destacadas: artigo de revisão e reflexão sobre o par conceitual “fluxos/fixos” proposto pelo geógrafo brasileiro Milton Santos. Reexamina-se a contribuição desse geógrafo, e exploram-se os desdobramentos dessa perspectiva teórica. Acrescenta-se um refinamento original através de uma tipologia mais especificada de diferentes tipos de fluxos e fixos.
High Glamour
Authors: Rodgers Charlotte 
Published: August 2020

The iconography and visuals associated with magic are highly evocative and responsible for a major part of its appeal. The strong, often iconoclastic imagery exerts a particularly powerful draw for the artist or craftsperson because of its ability to fire the imagination, and to inspire creative work in response. Until recent times, creative interpretations of magic within mainstream fashion have mainly been on a subtle and subversive level; generally within a counter cultural context. So why is magical symbolism being appropriated within high fashion at this particular point in time?
Breeding population increase and range expansion of the Great Crested Grebe Podiceps cristatus in southeastern Norway
Authors: Dale Svein 
Published: August 2020

The Great Crested Grebe Podiceps cristatus is listed as near-threatened on the Norwegian red list due to small population size, estimated in 2015 at 220–380 pairs. Population size is considered to be stable. Approximately one quarter of the population (50–100 pairs) is thought to occur in Oslo and Akershus, but this estimate is not based on detailed data, and the only previous systematic estimate was 90–100 pairs in 13 sites in 1982. In 2018, I conducted a comprehensive survey of all known and potential breeding sites to assess current population size in Oslo and Akershus. I recorded 233 pairs in 34 sites, suggesting a large increase in population size. To analyse the population increase in more detail, I collected all known records of Great Crested Grebes during the breeding season for the period 1995–2018. Analyses confirmed that there has been a strong increase, at a yearly rate of 4.2%. The increase was both due to increases in already established populations (69% of total increase), and establishment of new sites (31%). New sites were colonised in particular the last 10–15 years, and new sites were located gradually further away from the sites that were already used in 1982, indicating continuous range expansion. New sites were also located in smaller, less nutrient-rich lakes at higher elevations, perhaps indicating occupation of lower quality sites that could limit further population increase. Similar population increases have also occurred in other parts of the distribution range of Great Crested Grebes in Norway, and I present a new population size estimate for Norway at 531–634 pairs. Hence, the species no longer qualifies for red listing, and one may consider to downlist the species to least concern.

Cover photo: A pair of Great Crested Grebes with chicks. Photo: Frode Falkenberg.
Revista de Revistas
Authors: De Obstetricia y Ginecología Federación Colombiana 
Published: August 2020

Metastasis esqueleticas en el cancer del senoStaley. c. J. "Nuestra experiencia sobre huevo muerto y retenido" Votta R. A., Coll A. y Foix A "Rotura uterina" iso. R. y Agüero. El uso de agujas intersticiales de cobalto radioactivo en el tratamiento del carcinoma del cuelloEzell Holzaepfel. Am J.
UPAYA MELATIH KEMANDIRIAN BELAJAR MELALUI OUTDOOR LEARNING (ODL) SISWA KELAS III SDN PUCANG 4 SIDOARJO
Authors: Octavia Rosyidah Umami 
Published: August 2020

In doing interaction during learning process in the classroom, most of the students are less independence. This research is an effort to practice independent of students’ learning through outdoor learning This study uses a qualitative approach, which is research that produces descriptive data in the form of written and oral words from people and observable behavior. This type of research is a descriptive study, the researcher investigates the circumstances, conditions, situations, events, and activities, the results of which are presented in the form of research reports. While the type of research used is descriptive, namely by describing systematically the description and explanation of the data obtained in the study and the phenomena investigated based on the problem formulation. Based on the result of students’ learning observation, the mean value of students’ activities in first meeting is 2,967, the second meeting is 3,562, and the last meeting is 3,931. The conclusion of this research show that the third grade students of SD Negeri Pucang 4 Sidoarjo are very enthusiastic and happy in learning process. Therefore, the interaction of learning process can be done based on our hope.
DIFFERENCES OF INTERLEUKIN-18 AND INTERLEUKIN-10 LEVELS IN RIFAMPICIN RESISTANT AND RIFAMPICIN SENSITIVE PULMONARY TUBERCULOSIS PATIENTS IN DR. SOETOMO HOSPITAL SURABAYA
Authors: Riwu Audrey Gracelia , Nugaraha Jusak , Dachlan Yoes Prijatna 
Published: August 2020

Rifampicin is an anti-tuberculosis drug which has an efficient antimicrobial effect and the basis of a short-term treatment regimen for tuberculosis (TB) patients. Rifampicin plays an important role against the growth and slow metabolism of Bacilli M. tuberculosis. Resistance to rifampicin causes the duration of tuberculosis treatment to be longer. Interleukin-18 (IL-18) is a pro-inflammatory cytokine which plays a role in controlling the growth of M. tuberculosis through its ability to induce IFN-γ, while Interleukin-10 (IL-10) is an anti-inflammatory cytokine which plays a role in limiting tissue damage due to the inflammatory process and maintain tissue homeostasis. IL-18 and IL-10 has an important role in explaining the different degrees of inflammation in rifampicin resistant (RR) and rifampicin sensitive (RS) pulmonary tuberculosis patients. The purpose of this study is to determine different levels of IL-18 and IL-10 in new TB patients with RR and RS. This study was a retrospective cohort study with a cross-sectional design carried out from August-November 2018 in the TB-DOTS/MDR clinic at Dr. Soetomo Hospital, Surabaya. 50 research subjects were examined and grouped into two groups, namely pulmonary TB with RR (n = 25) and pulmonary TB with RS (n = 25) based on GeneXpert examination and anti-tuberculosis drug therapy ≤ 1 month. IL-18 and IL-10 were measured using the ELISA Method. Differences in IL-18 and IL-10 levels between groups were analyzed using the Mann-Whitney test. The mean level of IL-18 (pg/ml) in RR and RS pulmonary TB patients were 1273.53±749.86 and 787.96 ±589.28 respectively. The mean level of IL-10 (pg/ml) in RR and RS pulmonary TB patients were 125.25±118.32 and 128.81±135.77 repectively. The mean level of IL-18 in RR and RS pulmonary TB patients were found to have a significant difference, while the mean level of IL-10 did not have a significant difference. Keywords: Interleukin-18, Interleukin-10, Tuberculosis, Rifampicin Resistant, Rifampicin Sensitive
Postoperative Urinary Retention in Patients Who Undergo Joint Arthroplasty or Spine Surgery
Authors: Karani Rajiv , Mahdy Ayman , Asghar Ferhan 
Published: August 2020

» Postoperative urinary retention (POUR) may result from orthopaedic procedures and potentially lead to bacteremia and chronic voiding difficulties.» Risk factors for POUR include age, undergoing joint arthroplasty, male sex, intraoperative intravenous fluid administration, operative time, and history of benign prostatic hyperplasia.» Indwelling catheterization is the preferred management strategy for patients at risk for developing POUR.» A consistent definition of POUR is needed in order to draw conclusions from future studies.
Pengembangan E-Learning Mata Kuliah Profesi Keguruan Berbasis Moodle Untuk Model Blended Learning Di Universitas Islam Malang
Authors: Widodo Ganjar Setyo , Hidayah Layli 
Published: August 2020

Abstract: This study aims to develop E-Learning of “Mata Kuliah Profesi Keguruan” to be Blended Learning subjects. The method used in this research is the development research method using the ADDIE (Analysis-Design-Develop-Implement-Evaluate) model. Based on the results of the study, it can be concluded that e-learning of “Mata Kuliah Profesi Keguruan” has met the validity criteria with a value of 97.093% from expert validators. The product trial results with students obtained a positive response that is equal to 90% with the criteria of "very good".
Abstrak: Penelitian ini bertujuan untuk mengembangkan E-Learning pada Mata kuliah Profesi Keguruan menjadi mata kuliah Blended Learning. Metode yang digunakan dalam penelitian ini yaitu metode penelitian pengembangan dengan model ADDIE (Analysis-Design-Develop-Implement-Evaluate). Berdasarkan hasil penelitian, dapat disimpulkan bahwa e-learning mata kuliah Profesi Keguruan telah memenuhi kriteria kevalidan dengan nilai 97,093% dari validator ahli. Hasil uji coba produk dengan mahasiswa diperoleh respon yang positif yaitu sebesar 90% dengan kriteria “sangat baik”.
Aktivitas di Sekolah Diliburkan saat Pendemi Covid-19: Bagaimana Pembelajaran yang Dilakukan?
Authors: Wijayanto Sukma , Handani Dita Febri , Wardana Aditia Eska , Hajron Kun Hisnan 
Published: August 2020

Abstract. This study aims to describe the learning activities carried out at Cacaban 6 Elementary School in Magelang City during the Covid-19 pandemic. This study uses a qualitative descriptive approach to obtain information from informants in learning activities. The informants in the study were the teachers taken as a sample of six people and a school principal. The results obtained from this study indicate that learning activities are carried out in two ways, namely online via the Whatsapp application, Youtube, and Google form and offline or face to face. The findings of this study reinforce the implementation of learning activities policy that must be carried out by utilizing technology during the Covid-19 pandemic. It also strengthens the participation of parents to continue to be involved in the learning process of students, thus requiring them to always be communicative. The findings of this study can be a basis for following up on the policy of learning activities from home and efforts to solve the problem. In addition, this research can be the basis for conducting further studies in relation to learning activities during the pandemic.
Abstrak. Penelitian ini bertujuan mendeskripsikan pembelajaran yang dilakukan dalam pandemi Covid-19 di SD Negeri Cacaban 6 Kota Magelang. Penelitian menggunakan pendekatan deskriptif kualitatif untuk mendapatkan informasi dalam kegiatan pembelajaran. Informan dalam penelitian sebanyak 6 guru dan kepala sekolah. Hasil yang didapatkan bahwa pembelajaran dilakukan secara daring (wa, youtube, dan google form) dan luring. Temuan penelitian ini menguatkan pelaksanaan pembelajaran pada masa aktivitas libur pandemi covid 19 dalam memanfaatkan teknologi dan mengatasi keterbatasan seperti kurangnya keterlibatan orang tua dalam pembelajaran serta keterbatasan fasilitas serta harus komunikatif dengan orang tua.Temuan penelitian ini dapat menjadi landasan untuk tindak lanjut dalam pembelajaran, dan upaya-upaya pemecahan masalah. Disamping itu penelitian ini dapat menjadi landasan untuk melakukan kajian lebih dalam dalam hubungannya dengan pembelajaran yang dilakukan saat pendemi.
Linking marine core lithofacies and mineral and grain-size compositions on the Baffin Island margin: changes in provenance and transport
Authors: Andrews John T. , Jenner Kimberley A. , Campbell Calvin 
Published: August 2020

ABSTRACT
We evaluate the linkages between lithofacies and mineral composition of late Quaternary sediments along the Baffin Slope for cores 2013029 64, 74, and 77. Four major lithofacies were identified: diamicton (L1), laminated red-brown mud (L2), tan carbonate mud (L3), and brown bioturbated mud (L4). In addition, gold-brown mud (L2a) beds were identified within red-brown mud throughout the Baffin margin and a thin, locally distributed light gray mud (L2b), also identified within red-brown mud, was localized to the Home Bay region. A classification decision tree (CDT) correctly predicted ∼ 87% of the lithofacies based on five binary choices based on the estimated weight %s of (in order): quartz, kaolinite, plagioclase, iron oxides, and smectites. The detrital tan carbonate (DC) minerals, calcite and dolomite, did not appear in the chosen CDT solution although this lithofacies is easily recognized in cores because of its tan color and the facies is well predicted in the CDT. The addition of grain size did not substantially improve the prediction of the lithofacies although it did change the % importance of the minerals in the CDT.
Sequence stratigraphic framework of the mid-Cretaceous nonmarine Potomac Formation, New Jersey and Delaware
Authors: Thornburg Jesse D. , Miller Kenneth G. , Browning James V. 
Published: August 2020

ABSTRACTWe developed a sequence stratigraphic framework for the (Barremian to lower Cenomanian) fluvial–deltaic (primarily delta plain) Potomac Formation in the Medford, New Jersey, Fort Mott, New Jersey, and Summit Marina, Delaware coreholes. Previous studies have correlated distinctive lithologic units with attendant pollen zones and identified tentative sequence boundaries between lithologic units I (Barremian to lower Aptian, pollen Zone I), II (Aptian to lowermost Cenomanian, pollen Zone II), and III (lower Cenomanian, pollen Zone III) at all three sites. Here, we further subdivide these units into packages known as fluvial aggradation cycles (FACs). An analysis of FAC stacking patterns reveals potential sequence boundaries and systems tracts. FACs indicate that major lithologic unit boundaries are also sequence boundaries, indicate tentative higher-order sequence boundaries, and provide potential additional correlative surfaces among Potomac Formation sites. Our study demonstrates the applicability of the FAC method to identify stacking patterns and sequence stratigraphic surfaces in fluvial–deltaic deposits and demonstrates that FACs are excellent tools to decipher the difficult-to-correlate surfaces.
Scaling of Mechanical Degradation of EOR Polymers: From Field-Scale Chokes to Capillary Tubes
Authors: Stavland Arne , Åsen Siv Marie , Mebratu Amare , Gathier Flavien 
Published: August 2020

Summary
Polymer flooding is a well-known method for enhanced oil recovery (EOR). Synthetic EOR polymers are susceptible to mechanical degradation. Understanding and mitigating mechanical degradation is a key issue for successful polymer flooding.
The main concern of this work is mechanical degradation during choking. Offshore, it is necessary to have control over the injection pressure to each well. During traditional waterflooding, this is achieved by choking the fluid stream by choke valves. In choke valves, there will be sudden change in the flow field, strongly indicating that choke valves will cause mechanical degradation of polymers and thereby reduce the EOR potential of the polymer flood.
In this study we investigate mechanical degradation of conventional synthetic EOR polymers. The experiments were performed in commercial chokes and pipes with internal diameters (IDs) from 0.127 to 35 mm, lengths from 13.5 mm to 400 m, and flow rates from 0.3×10−3 to 600 dm3/min, covering several magnitudes of Reynolds number, linear velocities, shear rates, and pressure drop.
Using friction factors, f, and Reynolds number, Re, we derived a simple and practical expression for a scaling parameter, τw/η, for degradation of shear thinning polymers in circular tubes at turbulent and laminar flow, where τw=f8ρ⟨v⟩2. At laminar flow, the friction factor is ∝1Re, resulting in a scaling parameter proportional to the velocity-to-radius ratio, ∝⟨v⟩R, equal to the shear rate at the wall and practically independent of viscosity. At turbulent flow, the friction factor is ∝1Reβ, resulting in a scaling parameter at turbulent flow, which is a function of density and viscosity and valid only for high shear rates where the viscosity of shear thinning polymers approaches a fixed value.
During the large-scale test, several methods for mitigating or decreasing degradation as a function of pressure drop were identified: decreasing the pressure with several chokes in series, each below a critical pressure drop; decreasing the pressure over a long distance in a linear pressure reducer (LPR); or by choking concentrated polymer solution.
Patient-individual cancer cell lines and tissue analysis delivers no evidence of sequences from DNA viruses in colorectal cancer cells
Authors: Gock Michael , Kordt Marcel , Matschos Stephanie , Mullins Christina S. , Linnebacher Michael 
Published: August 2020

Abstract
Background: Several DNA viruses are highly suspicious to have oncogenic effects in humans. This study investigates the presence of potentially oncogenic viruses such as SV40, JCV, BKV and EBV in patient-derived colorectal carcinoma (CRC) cells typifying all molecular subtypes of CRC. Methods: Sample material (gDNA and cDNA) of a total of 49 patient-individual CRC cell lines and corresponding primary material from 11 patients, including normal, tumor-derived and metastasis-derived tissue were analyzed for sequences of SV40, JVC, BKV and EBV using endpoint PCR. In addition, the susceptibility of CRC cells to JCV and BKV was examined using a long-term cultivation approach of patient-individual cells in the presence of viruses. Results: No virus-specific sequences could be detected in all specimens. Likewise, no morphological changes were observed and no evidence for viral infection or integration could be provided after long term CRC cell cultivation in presence of viral particles. Conclusions: In summary, the presented data suggest that there is no direct correlation between tumorigenesis and viral load and consequently no evidence for a functional role of the DNA viruses included into this analysis in CRC development.