bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxidation during magma mixing recorded by symplectites at Kusatsu–Shirane Volcano, Central Japan
Authors: Ueki Kenta , Inui Mutsuko , Matsunaga Kenta , Okamoto Naoya , Oshio Kazuki 
Published: May 2020

AbstractKusatsu–Shirane Volcano is an active Quaternary andesitic-to-dacitic volcano located in the Central Japan Arc. We conducted a detailed petrological investigation of orthopyroxene (opx)–magnetite (mt) symplectites associated with olivine in the Sessho lava, an andesitic lava flow from Kusatsu–Shirane. We concluded that the symplectites are pseudomorphs after olivine and were formed through the breakdown of olivine in a mafic magma as a result of oxidation during mixing with a felsic magma. Various olivines and opx–mt symplectites that show different stages of the progressive breakdown reaction of olivine coexist in a single lava flow. We suggest that basaltic recharge into the magma reservoir beneath Kusatsu–Shirane occurred repeatedly, leading to a hybrid andesite magma with different types of olivine and symplectite being erupted at Kusatsu–Shirane Volcano.
Tibial condylar valgus osteotomy – indications and technique
Authors: Kuwashima Umito , Yonekura Akihiko , Itoh Masafumi , Itou Junya , Okazaki Ken 
Published: May 2020

Abstract
Purpose
To describe the indications for, and surgical technique of, tibial condylar valgus osteotomy (TCVO).

Indications
TCVO is commonly performed in patients with middle-to-end-stage medial unicompartmental osteoarthritis. Among the most important TCVO indication criteria are the types of tibial plateau shape. The convex-type (also called “pagoda-type”), with over a 5° joint line convergence angle on the standing X-ray, meets the indication criteria for TCVO.

Surgical technique
An L-shaped osteotomy is performed from the medial side of the proximal tibia to the lateral beak of the intercondylar eminence. The apex of the L-shaped osteotomy line is on the medial border of the patellar tendon insertion. Surgeons should note the direction of the chisel (during the osteotomy) to the intercondylar eminence following fluoroscopic guidance. The posterior cortical bone is cut under a lateral view observation, and the crossed-leg position is adopted to prevent injury to the popliteal blood vessels. The spreader should be positioned at the posterior cortical bone to avoid increasing the tibial slope. The locking plate reliably stabilizes the osteotomy and helps shorten the period of postoperative rehabilitation.

Conclusions
TCVO adjusts varus deformity alongside joint congruity. Accurate identification of indications and a detailed surgical plan would ensure effective correction and proper alignment. Additional osteotomies are recommended in case of under-correction of the varus limb deformity. TCVO is an effective intervention in patients with advanced knee osteoarthritis and lateral joint laxity with the pagoda-type tibial plateau shape.
Wine psychology: basic & applied
Authors: Spence Charles 
Published: May 2020

AbstractBasic cognitive research can help to explain our response to wine, and the myriad factors that affect it. Wine is a complex, culture-laden, multisensory stimulus, and our perception/experience of its properties is influenced by everything from the packaging in which it is presented through the glassware in which it is served and evaluated. A growing body of experiential wine research now demonstrates that a number of contextual factors, including everything from the colour of the ambient lighting through to background music can exert a profound, and in some cases predictable, influence over the tasting experience. Sonic seasoning - that is, the matching of music or soundscapes with specific wines in order to accentuate or draw attention to certain qualities/attributes in the wine, such as sweetness, length, or body, also represents a rapidly growing area of empirical study. While such multisensory, experiential wine research undoubtedly has a number of practical applications, it also provides insights concerning multisensory perception that are relevant to basic scientists. Furthermore, the findings of the wine research are also often relevant to those marketers interested in understanding how the consumers’ perception of any other food or beverage product can potentially be modified.
Monitoring treatment effects in lung cancer-bearing mice: clinical CT and clinical MRI compared to micro-CT
Authors: Spiro Judith E. , Rinneburger Miriam , Hedderich Dennis M. , Jokic Mladen , Reinhardt Hans Christian , Maintz David , Palmowski Moritz , Persigehl Thorsten 
Published: May 2020

Abstract
Background
Compared to histology-based methods, imaging can reduce animal usage in preclinical studies. However, availability of dedicated scanners is limited. We evaluated clinical computed tomography (CT) and magnetic resonance imaging (MRI) in comparison to dedicated CT (micro-CT) for assessing therapy effects in lung cancer-bearing mice.

Methods
Animals received cisplatin (n = 10), sham (n = 12), or no treatment (n = 9). All were examined via micro-CT, CT, and MRI before and after treatment. Semiautomated tumour burden (TB) calculation was performed. The Bland-Altman, receiver operating characteristic (ROC), and Spearman statistics were used.

Results
All modalities always allowed localising and measuring TB. At all modalities, mice treated with cisplatin showed a TB reduction (p ≤ 0.012) while sham-treated and untreated individuals presented tumour growth (p < 0.001). Mean relative difference (limits of agreement) between TB on micro-CT and clinical scanners was 24.7% (21.7–27.7%) for CT and 2.9% (−4.0–9.8%) for MRI. Relative TB changes before/after treatment were not different between micro-CT and CT (p = 0.074) or MRI (p = 0.241). Mice with cisplatin treatment were discriminated from those with sham or no treatment at all modalities (p ≤ 0.001). Using micro-CT as reference standard, ROC areas under the curves were 0.988–1.000 for CT and 0.946–0.957 for MRI. TB changes were highly correlated across modalities (r ≥ 0.900, p < 0.001).

Conclusions
Clinical CT and MRI are suitable for treatment response evaluation in lung cancer-bearing mice. When dedicated scanners are unavailable, they should be preferred to improve animal welfare.
Server-aided immediate and robust user revocation mechanism for SM9
Authors: Sun Shuzhou , Ma Hui , Zhang Rui , Xu Wenhan 
Published: May 2020

AbstractAs the only approved Identity-Based Encryption scheme in China that is also standardized by ISO, SM9-IBE has been widely adopted in many real-world applications. However, similar to other IBE standard algorithms, SM9-IBE currently lacks revocation mechanism, which is vital for a real system. Worse still, we find that existing revocable techniques may not be suitable and efficient when applying to SM9-IBE. Given the widespread use of SM9-IBE, an efficient and robust user revocation mechanism becomes an urgent issue.In this work, we propose a dedicated server-aided revocation mechanism, which for the first time achieves the secure, immediate and robust user revocation for SM9-IBE. Provided with a compact system model, the proposed method leverages an existing server to perform all heavy workloads during user revocation, thus leaving no communication and computation costs for the key generation center and users. Moreover, the mechanism supports key-exposure resistance, meaning the user revocation mechanism is robust even if the revocation key leaks. We then formally define and prove the security. At last, we present theoretical comparisons and an implementation in terms of computational latency and throughput. The results indicate the efficiency and practicability of the proposed mechanism.
In Vitro Release of 5-Fluorouracil and Methotrexate from Different Thermosensitive Chitosan Hydrogel Systems
Authors: Mohammed Ahmed M. , Osman Shaaban K. , Saleh Khaled I. , Samy Ahmed M. 
Published: May 2020

Abstract5-Fluorouracil is a member of cytotoxic drugs with poor selectivity to cancer cells. Currently, systemic administration of this anti-cancer drug (oral or injection) exposes normal tissues to the drug-induced toxicity. Nowadays, attention has been greatly directed towards in situ gel-forming systems that can be injected into the affected tissues in its sol form with a minimally invasive technique. More specifically, chitosan hydrogel systems were in focus due to their antibacterial effect as well as their biodegradable, biocompatible, and mucoadhesive properties. In the present work, 5-fluorouracil was loaded on various thermosensitive chitosan hydrogel systems cross linked with different linking agents like β-glycerophosphate, pluronic F127, and hydroxyapatite. Also, methotrexate was added to 5-fluorouracil in order to gain its previously reported synergistic effects. Firstly, a compatibility study was performed using UV-spectrophotometric, infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) techniques to exclude the possibility of any physical or chemical interactions between the selected drugs and excipients. The prepared hydrogel systems were characterized for their physicochemical properties including organoleptic, pH, syringeability and injectability, viscosity, and gelation temperature (Tgel) by various analysis techniques. Moreover, the in vitro release behavior of 5-fluorouracil and methotrexate was determined with a modified analytical method. The results indicated that chitosan hydrogel system cross-linked with a combination of β- glycerophosphate, and 10 % pluronicF127 (F4) showed the most suitable physicochemical properties and release profile. Accordingly, this formula can be considered as a missionary system for localized sustained delivery of cytotoxic drugs.
Improved reperfusion following alternative surgical approach for experimental stroke in mice
Authors: Trotman-Lucas Melissa , Wong Raymond , Allan Stuart M. , Gibson Claire L. 
Published: May 2020

Background: Following ischemic stroke, recanalisation and restoration of blood flow to the affected area of the brain is critical and directly correlates with patient recovery. In vivo models of ischemic stroke show high variability in outcomes, which may be due to variability in reperfusion. We previously reported that a surgical refinement in the middle cerebral artery occlusion (MCAO) model of stroke, via repair of the common carotid artery (CCA), removes the reliance on the Circle of Willis for reperfusion and reduced infarct variability. Here we further assess this refined surgical approach on reperfusion characteristics following transient MCAO in mice. Methods: Mice underwent 60 min of MCAO, followed by either CCA repair or ligation at reperfusion. All mice underwent laser speckle contrast imaging at baseline, 24 h and 48 h post-MCAO. Results: CCA ligation reduced cerebral perfusion in the ipsilateral hemisphere compared to baseline (102.3 ± 4.57%) at 24 h (85.13 ± 16.09%; P < 0.01) and 48 h (75.04 ± 12.954%; P < 0.001) post-MCAO. Repair of the CCA returned perfusion to baseline (94.152 ± 2.44%) levels and perfusion was significantly improved compared to CCA ligation at both 24 h (102.83 ± 8.41%; P < 0.05) and 48 h (102.13 ± 9.34%; P < 0.001) post-MCAO. Conclusions: Our findings show CCA repair, an alternative surgical approach for MCAO, results in improved ischemic hemisphere perfusion during the acute phase.
Anosmia and dysgeusia in COVID-19: A systematic review
Authors: Carrillo-Larco Rodrigo M. , Altez-Fernandez Carlos 
Published: May 2020

Background: This systematic review had three aims: i) to determine the frequency of anosmia (or other smell disorders) and dysgeusia (or other taste disorders) in COVID-19 patients; ii) to determine whether anosmia or dysgeusia are independently associated with COVID-19 diagnosis; and iii) to determine whether anosmia or dysgeusia are prognostic factors for impaired outcomes among COVID-19 patients. Methods: On April 20th, 2020, we search MEDLINE, Embase, Global Health, Scopus, Web of Science and MedXriv. We used terms related to COVID-19, smell and taste disorders. We selected case series, cross-sectional, case-control and cohort studies. We included studies with COVID-19 patients describing their symptoms; studies that compared smell and taste disorders between COVID-19 patients and otherwise healthy subjects; and studies comparing smell and taste disorders between COVID-19 severe and mild/moderate cases. Because of methodological heterogeneity and the limited number of results, a qualitative synthesis is presented. Results: From 31 reports, we selected six (n=2,757). Six studies reported the proportion of smell and taste disorders among COVID-19 patients. Two reports studied whether smell and taste disorders were independently associated with COVID-19 diagnosis. No reports studied the association with impaired outcomes among COVID-19 patients. The frequency of anosmia ranged between 22%-68%. The definition of taste disorders varied greatly, with dysgeusia present in 33% and ageusia in 20%. People who reported loss of smell and taste had six-fold higher odds of being COVID-19 positive; similarly, anosmia and ageusia were associated with 10-fold higher odds of COVID-19 diagnosis. Conclusions: The frequency of smell and taste disorders is as high as other symptoms, thus, at least anosmia for which the definition was more consistent, could be included in lists of COVID-19 symptoms. Although there is promising evidence, it is premature to conclude that smell and taste disorders are strongly associated with COVID-19 diagnosis. Registration: PROSPERO CRD42020181308
Newsvendor Decisions with Two-Sided Learning
Authors: Papanastasiou Yiangos 
Published: May 2020

A substantial collection of work in operations management considers settings where a firm faces uncertain demand that depends on parameters that are ex ante unknown but can be learned by observing historical data. This work typically assumes that future demand is unaffected by the firm’s learning process. However, in the new era of social media, it is increasingly the case that the information used by the firm to gauge future demand (for example, sales and stockouts or consumer feedback) is now also observable to the consumers and may influence their purchase decisions. In this paper, we consider a newsvendor model where a product of ex ante unknown value is sold in an environment where learning is “two-sided” in that both the firm and the consumers learn the product’s value over time by observing the same information. The analysis establishes a consequential insight: When learning is two-sided, the value of information is often negative for the firm; as a result, the firm’ optimal stocking quantity is often lower than that under one-sided learning. Moreover, under certain conditions that we identify, we show that the optimal stocking quantity can be even lower than the critical fractile policy, in stark contrast to the recurring prescription found in existing literature of “stocking more” in the presence of learning. Additional results and numerical experiments suggest that the loss for the firm from failing to account for the two-sidedness of the learning process can be significant. This paper was accepted by Charles Corbett, operations management.
A ESPACIALIDADE DA COVID-19 E O PANDEMÔNIO EM MEIO A PANDEMIA NAS COMUNIDADES TRADICIONAIS DA CAJAÍBA – PARATY
Authors: Said Abbul Mahmebb 
Published: May 2020

A nova pandemia que se agrava na atualidade coloca em xeque as formas de ocupação do espaço, os padrões de consumo e o próprio modelo de produção e exploração do meio ambiente. Apesar das multivariáveis que envolvem a questão do surgimento da pandemia, o vírus vem se espalhando pelos mercados financeiros da economia global e nos mercados locais. As interações espaciais globais orientadas pelas verticalidades em detrimento das horizontalidades tencionam e desorientam as ordens e desordens que chegam aos lugares, geram incertezas na implementação de políticas públicas de inclusão das camadas mais vulneráveis socialmente diante do espraiamento espacial do novo coronavírus, principalmente em redutos mais isolados como Paraty-RJ, onde se encontram instaladas comunidades tradicionais pesqueiras em lugares de difícil acesso. Em se tratando da chegada do vírus em Paraty, a pandemia já causa pandemônio entre as comunidades costeiras e com o aviltamento nos preços do principal meio de subsistência dessas famílias, o cenário que se apresenta é o de aprofundamento da crise sanitária e social nessas comunidades. O objetivo deste ensaio é discutir a espacialidade da Covid-19 nas comunidades tradicionais caiçaras e pesqueiras de Cajaíba (Paraty) e analisar suas consequências na pesca artesanal e nos modos de vida.
High-sensitivity, high-spatial-resolution distributed strain sensing based on a poly(methyl methacrylate) chirped fiber Bragg grating
Authors: Lyu Chengang , Liu Ziqi , Huo Ziqiang , Ge Chunfeng , Cheng Xin , Tam Haw-Yaw 
Published: May 2020

In this study, a high-sensitivity, high-spatial-resolution distributed strain-sensing approach based on a poly(methyl methacrylate) chirped fiber Bragg grating (CFBG) is proposed and experimentally demonstrated. Linearly chirped FBGs in a polymer optical fiber provide an alternative to the silica fiber owing to the lower Young’s modulus, which can yield a higher stress sensitivity under the same external force. According to the spatial wavelength-encoded characteristic of the CFBG, a fully distributed strain measurement can be achieved by optical frequency-domain reflectometry. Through time-/space-resolved short-time Fourier transform, the applied force can be located by the beat frequency originated from the space-induced time delay and measured by the differential frequency offset originated from the strain-induced dispersion time delay. In a proof-of-concept experiment, a high spatial resolution of 1 mm over a gauge length of 40 mm and a strain resolution of 0.491 Hz/με were achieved.
Enrichment of Omega-3 from Anchovy (Stolephorus sp.) Fish Oil by Enzymatic Hydrolysis
Authors: Kosasih Wawan , Rosmalina Raden Tina , Muhdani Mohamad Robi , Arief Dede Zainal , Saepudin Endang , Priatni Sri 
Published: May 2020

Anchovy (Stolephorus sp.) is an economically important fish in Indonesia. Anchovy contains Omega-3 that important to maintain the health of the heart and brain. This study aimed to enrich the Omega 3 content of anchovy oil from the North Sea of West Java. The extraction of anchovy oil was carried out by the soxhlet method. Enrichment of omega 3 from anchovy fish oil is carried out by hydrolysis with a commercial lipase enzyme at concentration 500, 1000, 1500 and 2000 unit/600g fish oil, for 5, 10, 15 and 20 hour. Before hydrolysis, fish oil was added with solvent water, ethanol, toluene, and n-hexane. Omega 3 content of fish oil products were analyzed by using Gas Chromatography (GC) with FID detector with retention time 14.068 min and 15.506 min for α-Linolenat (ALA) and eicosapentaenoic (EPA), respectively. The results showed the highest omega 3 content (ALA 0.54% and EPA 1.103% ) was produced by addition n-hexane with a ratio 1:6 with the concentration of lipase was 1000 units for 20 hours.
Formação do professor que ensina matemática, ludicidade e narrativas: o que se pesquisou no Brasil
Authors: Silva Américo Junior Nunes da , Passos Cármen Lúcia Brancaglion 
Published: May 2020

Este artigo apresenta um estudo que dialogou com pesquisas de mestrado e de doutorado que tomaram a formação matemática de professores dos anos iniciais, em cursos de Pedagogia. Tais pesquisas foram desenvolvidas entre 1978 a 2012 e constaram dos mapeamentos realizados em dois trabalhos (FIORENTINI et al. 2002; FIORENTINI; PASSOS; LIMA, 2016). O estudo compôs a tese de doutoramento do primeiro autor, que investigou o que revelam narrativas de licenciandos do curso de Pedagogia da Universidade Federal de São Carlos (UFSCar), construídas ao longo da formação, sobre a ludicidade, o ensino de matemática na formação inicial e o constituir-se professor que ensina(rá) matemática nos anos iniciais. Os dados aqui discutidos foram delimitados a partir do objeto da pesquisa de doutorado e de certo modo indicou o que de inédito poderia ser produzido. Tomou-se como fonte de dados as pesquisas levantadas pelos mapeamentos, com o olhar voltado para os trabalhos que tiveram a “ludicidade” como aspecto importante da formação inicial do professor que ensinará matemática nos anos iniciais e/ou utilizou “narrativas” ou se apresentaram como “pesquisas narrativas” – elementos que se articulam ao puzzle (CLANDININ; CONNELLY, 2015) de pesquisa, relacionamos 41 pesquisas. Ao dialogar com os autores das pesquisas buscamos neste artigo conhecer conceitos apresentados nas mesmas, confrontá-los com referenciais teóricos que defendem a ludicidade e a escrita de narrativas na formação inicial de professores que ensinam(rão) matemática nos anos iniciais.
LA CONCEPCIÓN ARISTOTÉLICA DE LA SABIDURÍA EN SOBRE LA FILOSOFÍA
Authors: Seggiaro Claudia 
Published: May 2020

El objetivo de este trabajo es analizar la relación entre la concepción de la sabiduría y el uso de metáforas lumínicas presentes en los fragmentos 8b y 8c de Sobre la filosofía. Al hacer esto, nos interesa establecer si el uso de esta metáfora responde a la utilización que Aristóteles hace de términos perceptuales en otras obras, como la Física, la Metafísica, Sobre el alma y el Protréptico. El objetivo de este análisis es examinar si, al hacer uso de la metáfora lumínica en estos fragmentos, Aristóteles supone la distinción entre “lo más más conocido en sí” y “lo más conocido para nosotros”, presentada en las obras arriba mencionadas como “lo más claro en sí” y “lo más claro para nosotros”, esto es, en términos perceptuales.
TRADUCCIÓN Y CANONIZACIÓN DE TEXTOS CON ESPECIAL REFERENCIA A LAS TRADUCCIONES LATINAS DE LOS PHAENOMENA DE ARATO
Authors: Cerra Maria Gabriela 
Published: May 2020

El presente artículo discute de qué modo consideraciones lingüísticas y estilísticas son significativas o incluso críticas para la aceptación, la supervivencia y en última instancia para el status canónico de una obra literaria. La elección del tema, el estilo y los procesos de traducción son factores que influenciaron el status y la suerte de muchas composiciones literarias. Usamos este criterio para examinar el caso de los Phaenomena de Arato, uno de los poemas más exitosos de la antigüedad. Nuestro artículo analiza de qué modo las traducciones de Cicerón, Germánico y Avieno contribuyeron a su popularidad y supervivencia.
ACUERDO Y DESACUERDO EN LA ILÍADA. UN ANÁLISIS DE KATA MOIPAN Y KAT’AI ΣAN COMO MARCADORES DISCURSIVOS
Authors: Marinoni Betiama P. 
Published: May 2020

En los últimos años, la validez de aplicar parámetros específicos de la teoría de la pragmática del lenguaje a los poemas homéricos, y a las lenguas clásicas, ha sido ampliamente comprobada. También este trabajo intenta demostrar que este tipo de abordaje permite una comprensión más profunda de los discursos persuasivos de la Ilíada. En efecto, el propósito del presente estudio es observar la utilización de los sintagmas preposicionales κατὰ μοῖραν y κατ’ αἶσαν como marcadores discursivos. Así, buscamos analizar por qué una reprimenda logra el éxito persuasivo al margen de la verdad enunciada acerca del código de conducta tradicional.
RETÓRICA, CRÍTICA LITERARIA Y CANON EN QUINTILIANO, INSTITUTIO ORATORIA 10.1
Authors: Iribarren Verónica , Jurado Melina 
Published: May 2020

El canon literario implica un proceso de selección sistemático y jerárquico de escritores, obras y géneros con el fin de delimitar un corpus modélico imitableligado fuertemente a la instrucción pedagógica. En el presente trabajo se analizará el particular proceso de formación y conformación del canon –así como surecepción y transformación respecto de los cánones previos– establecido por Quintiliano en el Libro 10 de la Institutio Oratoria, a fin de demostrar que los criterios de selección que guían dicho canon exceden la mera función didáctica.