bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refractory Hypertension and Risks of Adverse Cardiovascular Events and Mortality in Patients With Resistant Hypertension: A Prospective Cohort Study
Authors: Cardoso Claudia R. L. , Salles Gil F. 
Published: August 2020

Background
The long‐term prognosis of refractory hypertension (RfHT), defined as failure to control blood pressure (BP) levels despite an antihypertensive treatment with ≥5 medications including a diuretic and mineraloreceptor antagonist, has never been evaluated.

Methods and Results
In a prospective cohort study with 1576 patients with resistant hypertension, patients were classified as refractory or nonrefractory based on uncontrolled clinic (or office) and ambulatory BPs during the first 2 years of follow‐up. Multivariate Cox analyses examined the associations between the diagnosis of RfHT and the occurrence of total cardiovascular events (CVEs), major adverse CVEs, and cardiovascular and all‐cause mortality, after adjustments for other risk factors. In total, 135 patients (8.6%) had RfHT by uncontrolled ambulatory BPs and 167 (10.6%) by uncontrolled clinic BPs. Over a median Follow‐Up of 8.9 years, 338 total CVEs occurred (288 major adverse CVEs, including 124 myocardial infarctions, and 96 strokes), and 331 patients died, 196 from cardiovascular causes. The diagnosis of RfHT, using either classification by clinic or ambulatory BPs, was associated with significantly higher risks of major adverse CVEs, cardiovascular mortality, and stroke incidence, with hazard ratios varying from 1.54 to 2.14 in relation to patients with resistant nonrefractory hypertension; however, the classification based on ambulatory BPs was better in identifying higher risk patients than the classification based on clinic BP levels.

Conclusions
Patients with RfHT, particularly when defined by uncontrolled ambulatory BP levels, had higher risks of major adverse CVEs and mortality in relation to patients with resistant but nonrefractory hypertension, supporting the concept of refractory hypertension as a true extreme phenotype of antihypertensive treatment failure.
Lord of the Storm and Oracular Decisions: Competing Construals of Storm God Imagery in Hosea 6:1–6
Authors: Lancaster Mason D. , Miglio Adam E. 
Published: August 2020

Abstract
The poetry of Hosea employs and engages the religious imagery from the Baʿlu cult in its construal of Israel’s deity, YHWH, as a storm god. The present article focuses on the varied uses of storm god imagery in Hos 6:1–6 and offers a new explanation for the abstruse imagery of verse 5 and for the polemical dynamics at play within 6:1–6. In particular, it treats the final colon of Hos 6:5, which has defied explanation by interpreters: wmšpṭy kʾwr yṣʾ.
Roots of Resurrection in the Tales of Daniel
Authors: Grillo Jennie 
Published: August 2020

Abstract
Early Jewish and early Christian readers found resurrection from the dead in the tales of Daniel; this article suggests that those readings may uncover real roots of the later theological idea within the earlier texts. The lions’ den of chs. 6 and 14 in the Greek texts and their daughter versions has intertextual connections with the pit which figures death in the Psalms, in Jeremiah, and in ancient Near Eastern iconography, and the dew which cools the furnace in the Greek versions of ch. 3 ties that chapter into a network of mythological allusions to the resurrecting power of dew. The Additions to Daniel and their early reception thus create a trajectory towards the later ideas which rabbinic and patristic readers built upon the substratum of these texts; in turn, those later ideas can be shown to have organic antecedents within the book of Daniel.
Traces of Wulfila’s Bible Translation in Visigothic Gaul
Authors: Falluomini Carla 
Published: August 2020

Abstract
The analysis of the biblical names transmitted by the – now lost – mosaic inscriptions of the church Notre-Dame de la Daurade, in Toulouse, suggests the possibility that they may represent the Latin adaptation of Gothic names deriving from Wulfila’s Bible translation. These forms would therefore be significant witnesses to the circulation of the Wulfilian text in Visigothic Gaul. They would also testify to the ongoing Latin acculturation of the new settlers in Gaul, or at least in the capital Toulouse, where the (relatively) peaceful relations with the Gallo-Romans, encouraged by a court open to Roman culture, may have promoted a rapid bilingualism – although not a complete assimilation – of the Visigothic population. The mosaic inscriptions of the Daurade would perfectly represent this cultural amalgamation, by joining the traditional religious belief (Arianism-Homoianism) and texts (Wulfila’s version) of the Goths, with forms of art (mosaics) and language of the Gallo-Romans.
A Juvenile Skeleton from a Classical Athenian Grave (No 48, 470–50 BC) Displaying Dental Developmental Abnormalities (Hypodontia)
Authors: Protopapa Anastasia-Sofia , Pitsios Theodoros 
Published: August 2020

Abstract
We studied an immature skeleton, recovered from a Classical Athenian Grave. We employed standard anthropological methodology for skeletal age-estimation. Additionally, odontognathic components were subjected to X-ray imaging analysis. We concluded that the skeletal finds under study represent a juvenile with a biological age ranging between 10 and 13 years with multiple disturbances involving practically the entire dentition. Evidence of craniofacial/dentofacial developmental abnormalities may represent isolated conditions or may constitute part of a more complex phenotype, i.e. may represent syndromic traits. These changes may have carried an aesthetic, functional and psychosocial burden for the young patient and his or her family.
Composition, Comparison, and Concept
Authors: Lloyd James 
Published: August 2020

Abstract
While recent discussions of music archaeology have emphasised the importance of context for the study of the art and archaeology of ancient music, there has not been much theoretical engagement with the objects themselves. This paper takes recent arguments concerning two objects identified as strobiloi to propose an object-based framework for the study of ancient art and archaeology in relation to ancient music. Contexts are not infallible. Being mindful of composition, comparisons, and concepts (the three core elements of the proposed framework), I argue that there is, as yet, no certain artistic or archaeological evidence for interpreting objects identified as strobiloi as musical devices, and that the Asteas Phrynis vase cannot be used as a reliable source for organological detail.
Neuropsychological Approaches to Visually-Induced Vection: an Overview and Evaluation of Neuroimaging and Neurophysiological Studies
Authors: Berti Stefan , Keshavarz Behrang 
Published: August 2020

Abstract
Moving visual stimuli can elicit the sensation of self-motion in stationary observers, a phenomenon commonly referred to as vection. Despite the long history of vection research, the neuro-cognitive processes underlying vection have only recently gained increasing attention. Various neuropsychological techniques such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) have been used to investigate the temporal and spatial characteristics of the neuro-cognitive processing during vection in healthy participants. These neuropsychological studies allow for the identification of different neuro-cognitive correlates of vection, which (a) will help to unravel the neural basis of vection and (b) offer opportunities for applying vection as a tool in other research areas. The purpose of the current review is to evaluate these studies in order to show the advances in neuropsychological vection research and the challenges that lie ahead. The overview of the literature will also demonstrate the large methodological variability within this research domain, limiting the integration of results. Next, we will summarize methodological considerations and suggest helpful recommendations for future vection research, which may help to enhance the comparability across neuropsychological vection studies.
Biochemistry and molecular aspects of 2-acetyl-1-pyrroline biosynthesis in rice (Oryza sativa L.): A review
Authors: Verma Deepak Kumar , Thakur Mamta , Srivastav Prem Prakash 
Published: August 2020

ABSTRACT
Rice is used as a staple food in many countries due to its pleasant aroma and texture. Rice aroma is recognized as the single most important quality trait influencing consumer’s acceptance. In rice quality, 2-acetyl-1-pyrroline (2-AP) is one of the most highly unstable and key aroma characteristic compounds among more than 500 identified compounds that have contributed and attributed for popcorn- or pandan-like valuable aroma. 2-AP has the lowest odor threshold value compared to other identified rice aroma compounds. Therefore, this compound has received a lot of attention among scientists and researchers. This review highlights on Molecular biology and biotechnological progress of 2-AP in rice. Chemistry, formation, and synthesis, as well as factors influencing 2-AP content in rice, have also been reviewed.
Long Vowels in Proto-Tungusic
Authors: Ryzhkov-Shukumine Alexandre 
Published: August 2020

Abstract
This paper reviews 98 etymologies for which a Proto-Tungusic reconstruction with a long vowel has been suggested. It is shown that primary long vowels in non-first syllables are preserved only in the Ewenic branch of Tungusic. On the other hand, a number of the diphthongs in Southern Tungusic must be considered original. Proto-Tungusic had a system of at least five diphthongs.
Old Korean and Proto-Korean *r and *l Revisited
Authors: Vovin Alexander 
Published: August 2020

Abstract
This article argues for new internal evidence for the existence of the contrast between *r and *l in Old Korean and Proto-Korean on the basis of the Hyangchal data and Old Japanese transcriptional glosses as well as Korean loanwords in Manchu and Jurchen that were not analyzed in this way before. Namely, I will argue that combined Old Korean and Middle Korean data call for the reconstruction of two different types of liquids in the position before *i: both stay intact in Old Korean, but in Middle Korean the first type undergoes elision, whereas the second type stays intact. I then attempt to identify these two types on the basis of the internal evidence and parallel phenomena attested in the Greater Manchuria linguistic area and elsewhere.
Norway Comes to New Zealand: Edward Kidson, Jørgen Holmboe, and the Modernization of Australasian Meteorology
Authors: Doolin Ciaran 
Published: August 2020

AbstractEdward Kidson, Director of the Meteorological Service of New Zealand from 1927 until his death in 1939, was an instrumental figure in modernizing Australasian meteorology. Throughout the 1920s, Kidson promoted the methods of synoptic analysis emanating from the Bergen School of Meteorology. However, it was not until the 1930s that he began in earnest to apply these methods to weather charts for the Australasian region. This development was aided by two visits he made to Bergen and by a personal correspondence he maintained with Jacob Bjerknes during the 1930s. In 1932, Kidson presented the first Norwegian-style analysis conducted for a Southern Hemisphere region, promptly following this with a more extensive study. However, these analyses were not of a sufficient standard at that stage to be adopted in forecasting practice. It was the fortuitous visit to New Zealand of Norwegian meteorologist Jørgen Holmboe, in 1934, that finally facilitated the transition. Holmboe was attached to the Lincoln Ellsworth Antarctic Expedition, but damage to their aircraft caused them to spend the winter of 1934 in New Zealand. Holmboe was engaged at the Meteorological Service in Wellington during this period, working with Kidson to apply Norwegian methods to the region. Kidson had hoped to further embed this practice by employing Tor Bergeron in New Zealand during 1938. Bergeron had accepted an offer from Kidson but canceled at the last minute after contracting rheumatic fever. Nevertheless, shortly after Holmboe’s visit, daily analyses were being conducted along Norwegian lines, bringing Australasian meteorology into the twentieth century.
Soil Moisture–Evapotranspiration Overcoupling and L-Band Brightness Temperature Assimilation: Sources and Forecast Implications
Authors: Crow Wade T. , Gomez Concepcion Arroyo , Sabater Joaquín Muñoz , Holmes Thomas , Hain Christopher R. , Lei Fangni , Dong Jianzhi , Alfieri Joseph G. , Anderson Martha C. 
Published: August 2020

AbstractThe assimilation of L-band surface brightness temperature (Tb) into the land surface model (LSM) component of a numerical weather prediction (NWP) system is generally expected to improve the quality of summertime 2-m air temperature (T2m) forecasts during water-limited surface conditions. However, recent retrospective results from the European Centre for Medium-Range Weather Forecasts (ECMWF) suggest that the assimilation of L-band Tb from the European Space Agency’s (ESA) Soil Moisture Ocean Salinity (SMOS) mission may, under certain circumstances, degrade the accuracy of growing-season 24-h T2m forecasts within the central United States. To diagnose the source of this degradation, we evaluate ECMWF soil moisture (SM) and evapotranspiration (ET) forecasts using both in situ and remote sensing resources. Results demonstrate that the assimilation of SMOS Tb broadly improves the ECMWF SM analysis in the central United States while simultaneously degrading the quality of 24-h ET forecasts. Based on a recently derived map of true global SM–ET coupling and a synthetic fraternal twin data assimilation experiment, we argue that the spatial and temporal characteristics of ECMWF SM analyses and ET forecast errors are consistent with the hypothesis that the ECMWF LSM overcouples SM and ET and, as a result, is unable to effectively convert an improved SM analysis into enhanced ET and T2m forecasts. We demonstrate that this overcoupling is likely linked to the systematic underestimation of root-zone soil water storage capacity by LSMs within the U.S. Corn Belt region.
Deep Eastern Boundary Currents: Realistic Simulations and Vorticity Budgets
Authors: Yang Xiaoting , Tziperman Eli , Speer Kevin 
Published: August 2020

AbstractConcentrated poleward flows near the eastern boundaries between 2- and 4-km depth have been observed repeatedly, particularly in the Southern Hemisphere. These deep eastern boundary currents (DEBCs) play an important role in setting the large-scale tracer distribution and have nonnegligible contribution to global transports of mass, heat, and tracers, but their dynamics are not well understood. In this paper, we first demonstrate the significant role of DEBCs in the southeastern Atlantic, Indian, and Pacific Oceans, using the Southern Ocean State Estimate (SOSE) data assimilating product, and using high-resolution regional general circulation model configurations. The vorticity balances of these DEBCs reveal that, over most of the width of such currents, they are in an interior-like vorticity budget, with the meridional advection of planetary vorticity βυ and vortex stretching fwz being the largest two terms, and with contributions of nonlinearity and friction that are of smaller spatial scale. The stretching is shown, using a temperature budget, to be largely forced by resolved or parameterized eddy temperature transport. Strongly decaying signals from the eastern boundary in friction and stretching form the dominant balance in a sublayer close to the eastern boundary. The temporal variability of DEBCs is then examined, to help to interpret observations that tend to be sporadic in both time and space. The probability distribution functions of northward velocity in DEBC regions are broad, implying that flow reversals are common. Although the regions of the simulated DEBCs are generally local minima of eddy kinetic energy, they are still constantly releasing westward-propagating Rossby waves.
Opening of BKCa channels alters cerebral hemodynamic and causes headache in healthy volunteers
Authors: Al-Karagholi Mohammad Al-Mahdi , Ghanizada Hashmat , Nielsen Cherie Amalie Waldorff , Skandarioon Camilla , Snellman Josefin , Lopez Lopez Cristina , Hansen Jakob Møller , Ashina Messoud 
Published: August 2020

Introduction Preclinical data implicate large conductance calcium-activated potassium (BKCa) channels in the pathogenesis of headache and migraine, but the exact role of these channels is still unknown. Here, we investigated whether opening of BKCa channels would cause headache and vascular effects in healthy volunteers. Methods In a randomized, double-blind, placebo-controlled, cross-over study, 21 healthy volunteers aged 18–39 years were randomly allocated to receive an intravenous infusion of 0.05 mg/min BKCa channel opener MaxiPost and placebo on two different days. The primary endpoints were the difference in incidence of headache and the difference in area under the curve (AUC) for headache intensity scores (0–12 hours) and for middle cerebral artery blood flow velocity (VMCA) (0–2 hours) between MaxiPost and placebo. The secondary endpoints were the differences in area under the curve for superficial temporal artery and radial artery diameter (0–2 hours) between MaxiPost and placebo. Results Twenty participants completed the study. Eighteen participants (90%) developed headache after MaxiPost compared with six (30%) after placebo ( p = 0.0005); the difference of incidence is 60% (95% confidence interval 36–84%). The area under the curve for headache intensity (AUC0–12 hours, p = 0.0003), for mean VMCA (AUC0–2 hours, p = 0.0001), for superficial temporal artery diameter (AUC0–2 hours, p = 0.003), and for radial artery diameter (AUC0–2 hours, p = 0.03) were significantly larger after MaxiPost compared to placebo. Conclusion MaxiPost caused headache and dilation in extra- and intracerebral arteries. Our findings suggest a possible role of BKCa channels in headache pathophysiology in humans. ClinicalTrials.gov, ID: NCT03887325.
To tele- or not to telehealth? Ongoing COVID-19 challenges for private psychiatry in Australia
Authors: Looi Jeffrey CL , Pring William 
Published: August 2020

Objectives: Following a very rapid and significant uptake of metropolitan telepsychiatry in private practice in Australia during COVID-19, practical questions remain: How long should psychiatrists continue telepsychiatry? Are there benefits of continuing: reduced COVID-19 risks to patient and psychiatrist, and flexibility of appointments? Will the Medicare Benefits Schedule (MBS) telehealth items be retained? How does metropolitan telepsychiatry fit into the overall mix of public and private services? This is an important debate. Conclusions: Private psychiatrists may continue to offer the majority of care, where practical, via telepsychiatry to reduce COVID-19 exposure risks, as well as allow for the realities of practice management for pandemic public health measures. However, consideration has to be given to the potential drawbacks for patients with sight, hearing and illness-related disabilities or risks, when in-person consultation is required. There are also risks: some patients may not benefit from telepsychiatry due to the nature of their illness, and will patients feel rapport is lost? However, the retention of COVID-19 MBS telehealth items is needed for ongoing flexible and comprehensive private practice psychiatry.
Progressive Collapsing Foot Deformity: Consensus on Goals for Operative Correction
Authors: Sangeorzan Bruce J. , Hintermann Beat , de Cesar Netto Cesar , Day Jonathan , Deland Jonathan T. , Ellis Scott J. , Johnson Jeffrey E. , Myerson Mark S. , Schon Lew C. , Thordarson David B. 
Published: August 2020

Recommendation: In the treatment of progressive collapsing foot deformity (PCFD), the combination of bone shape, soft tissue failure, and host factors create a complex algorithm that may confound choices for operative treatment. Realignment and balancing are primary goals. There was consensus that preservation of joint motion is preferred when possible. This choice needs to be balanced with the need for performing joint-sacrificing procedures such as fusions to obtain and maintain correction. In addition, a patient’s age and health status such as body mass index is important to consider. Although preservation of motion is important, it is secondary to a stable and properly aligned foot. Level of Evidence: Level V, consensus, expert opinion.
Surgical management of ptosis in chronic progressive external ophthalmoplegia
Authors: Eshaghi Mohammad , Arabi Amir , Eshaghi Sarvin 
Published: August 2020

Purpose: To determine possible complications and efficacy of ptosis surgery in a series of chronic progressive external ophthalmoplegia (CPEO) patients with healthy tear film. Method: It is a prospective interventional study on 24 eyes from 12 patients with the diagnosis of CPEO and ptosis. Pre-operatively, tear breakup test (TBUT) and Schirmer test were performed to assess lacrimal function unit. Levator resection was performed for 16 eyes with levator function (LF) more than 4 mm, while eight eyes from four patients with poorer LF underwent frontalis silicone sling surgery. Main outcome measures included change in marginal-to-reflex distance (MRD1) and incidence of post-operative exposure keratopathy. Results: The mean age of the patients was 45 ± 15 years. The mean of TBUT and Schirmer test were 12 ± 1.98 s and 15 ± 2.76 mm, respectively. The mean follow-up period was 34 months. Four eyes encountered mild to moderate exposure keratopathy. All cases were managed medically, with no need for surgical revision. The mean pre-operative MRD1, LF, and chin-up angle were −0.54 ± 1.03 mm, 4.21 ± 1.41 mm, and 21.6 ± 6.01 degrees, respectively. The mean post-operative MRD1, LF, and chin-up angle were 2.42 ± 0.60, 4.46 ± 1.53 mm, and 3.3 ± 1.01 degrees, respectively. At 1-year follow-up visit, improvement in MRD1 and chin-up posture was statistically significant ( p-value < 0.05). Conclusion: Normal TBUT and Schirmer test results, prophylactic lubricating therapy, and close follow-up can be as important as Bell’s phenomenon and palpebral fissure height in predicting post-operative complications.
Enhancing Resilience in Autistic Adults Using Community-based Participatory Research: A Novel HRD Intervention in Employment Service Provision
Authors: Farkas Tibor N. , Mendy John , Kargas Niko 
Published: August 2020

The Problem Although previous research suggests current human resource management (HRM) policies and procedures do not fully accommodate the diverse strengths and needs of jobseekers and employees on the autism spectrum, the human resource development (HRD) community, including its scholars, researchers and practitioners will benefit from learning more about autism and how people with the condition can develop resilience capacity at work. The Solutions Utilizing a community-based participatory research approach (CBPR), we recommend an Autism Work Peer Support Group (AWPSG) program as a new framework that can help the HRD community as well as HRM work coaches and disability employment advisors to foster environments, where people’s social adaptation is key for their resilience capacity development. The Stakeholders The current research provides a framework on how a CBPR approach could be utilized to operationalize the design and evaluation of an employment intervention (i.e., AWPSG) that could involve autistic jobseekers in the process of resilience building. Furthermore, our findings indicate that fostering the emergence of a subjectively meaningful employment-focused peer support group program could help enlighten the HRD community about the challenges faced by this particular group and thereby offer effective autism-HRD advice and support to autistic jobseekers, employees and employers, management, work-coaches and disability employment advisors.