bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic hepatotropic regimens in programs of accompanying nutritional support for cancer patients with colorectal cancer and pancreatic cancer: Remaxol in structure of infusion and nutritional therapy
Authors: Kostyuchenko L. N. , Kostyuchenko M. V. 
Published: January 2020

Infusion-nutrient accompanying therapy provides prevention of metabolic complications and their nutrient correction in oncopatients with colorectal cancer (CRС) and pancreatic cancer.Material and methods. In patients with CRС and pancreatic cancer the effectiveness of detoxification alimentation was evaluated. Nutritional deficiency was specified by alimental-volemic diagnoses (AVD), nutritional risk-by NRI, sarcopenia by bioimedansometry. Hematological indices of intoxication (Krebs index, leukocyte index of intoxication) were calculated according to known formulas. Hepatological parameters (total protein, albumin, bilirubin, ALT, etc.) and the content of blood urea and creatinine, electrolytes were determined by conventional methods, the participation of the intestine in detoxification was monitored by plasma citrulline levels and activity of the intestinal microbiota. The severity of the condition was assessed by APACHE II, the quality of life by ECOG.Results. The relationship between indicators of homeostasis and endotoxicosis, as well as more positive dynamics in the application of detoxification regimens with the addition of Remaxol.Conclusion. In CRC T3–T4, it is advisable to use a combination of nutrient compositions with the addition of hepatotropic pharmaconutrients, in particular, Remaxol.
Anxiety-depressive and asthenic disorders in patients older than 75 years with chronic brain ischemia
Authors: Abramova V. N. , Slyusar T. A. , Medvedeva C. L. 
Published: January 2020

Purpose of the study. To study the prevalence and severity of depression, anxiety and asthenia in patients older than 75 years with chronic brain ischemia (CBI) and their relationship with somatic burden.Materials and methods. 121 patients aged 75 to 95 years with CBI of two and three stage were examined (57 patients with ischemic stroke in anamnesis, 64 without stroke). We used the Beck’s questionnaire to determine the level of depression, State-Trait Anxiety Inventory (STAI) one for detecting anxiety, Multidimensional Fatigue Inventory (MFI-20) one for assessing the severity of asthenia. The level of burden of somatic pathology was calculate by the polymorbidity index.Results. A characteristic feature of patients older than 75 years with CBI is the high prevalence and severity of emotional disturbances (anxiety and depression), as well as asthenic syndrome, high values of the polymorbidity index, which is advisable to take into account when planning CBI therapy.
Changes in Tumor-Infiltrating Lymphocytes and Vascular Normalization in Breast Cancer Patients After Neoadjuvant Chemotherapy and Their Correlations With DFS
Authors: Wang Qiong , Xiang Qun , Yu Lan , Hu Ting , Chen Yangyang , Wang Jue , Nie Xiu , Cheng Jing 
Published: January 2020

Objective: Changes in the number of various tumor-infiltrating lymphocytes (TILs) and degrees of vascular normalization in breast cancer (BC) patients after neoadjuvant chemotherapy (NAC) were analyzed to screen key factors that can predict the prognosis.Methods: HE-stained sections were used to assess the degree of TILs infiltration; immunohistochemically stained sections were used to assess the infiltration of CD8+, CD4+, FOXP3+ Tregs and the expression of PD-L1; immunofluorescence-stained sections were used to assess the microvessel density (MVD) and microvessel pericyte coverage index (MPI). The expression of them before NAC were compared with those after NAC, and correlations between changes in these parameters and the pathological complete remission (pCR) and DFS of BC patients were analyzed.Results: After NAC, the percentage of patients with enhanced sTILs in the pCR group was significantly higher than that in the Non-pCR group (P &lt; 0.05). Univariate and multivariate analyses showed that the number of FOXP3+ Tregs and MPI before NAC were correlated with pCR (P &lt; 0.05). Survival analysis showed that the DFS of BC patients with reduced FOXP3+ Tregs was significantly better than that of patients with elevated FOXP3+ Tregs (P = 0.029). The sTILs count and MPI were significantly higher in primary tumors than lymph nodes (P &lt; 0.05).Conclusion: After NAC, the reduced infiltration of FOXP3+ Tregs was correlated with an improvement in DFS in BC patients. Changes in the number of FOXP3+ Tregs and the MPI may be used as prognostic markers for BC patients.
Analysis of Under-frequency Load Shedding (UFLS) Relay Setting during Disturbances
Authors: Sulistiawati Irrine Budi , Prastyo Angga Budi , Lomi Abraham , Priyadi Ardyono 
Published: January 2020

Load changes on the system will affect the system stability itself. Load demand that exceeds the generated power will cause the system frequency to decline. Therefore, a load shedding procedure is required to improve the frequency. This research focuses on how to design a load shedding scheme that is activated by the operation of under frequency relay. There are two scenarios to analyze the system performance with a simulation, which are losing power on line about 128 MVA and generator loss power about 192 MVA. Those scenarios result in a decrease in the system frequency to 47.48 Hz and 47.90, respectively. After the load shedding scenario is performed, the frequency became an increase in the range of 51.54 Hz and 49 Hz within a few seconds.
Między pamięcią a historią: animowana rewolucja irańska
Authors: Wiącek Elżbieta 
Published: January 2020

Totalna islamizacja, która zapanowała w irańskiej kulturze z początkiem lat 80. XX w., przyniosła zmianę wartości właściwych epoce dynastii Pahlawich lat 1921-1979. Otwartość na idee liberalizmu i modernizacji w duchu zachodnim (amerykańskim) została zastąpiona koncentracją uwagi na szyickim islamie. Na temat rewolucji w Iranie w 1979 r. powstało dziesiątki książek, artykułów i filmów. Wśród nich wyróżnia się Persepolis (2007) – francuski pełnometrażowy film animowany w reżyserowany przez Marjane Satrapi i Vincenta Paronnauda, na podstawie autobiograficznego komiksu o tym samym tytule, którego autorką jest Satrapi. Żaden z fabularnych przekazów audiowizualnych dotyczących rewolucyjnych wydarzeń nie miał takiego rozgłosu i nie stał się tak popularny w świecie Zachodu. Dlaczego to właśnie rysunkowa, bardzo subiektywna wersja historii XX-wiecznego Iranu sprawiła, że wydarzenia z izolowanego od czterech dekad kraju utożsamianego z fanatyzmem i terrorem stały się bliskie wielu widzom na całym świecie?
OS PROFESSORES DE CIÊNCIAS E SUAS FORMAS DE PENSAR A ASTRONOMIA
Authors: Leite Cristina , Hosoume Yassuko 
Published: January 2020

O modo de pensar dos professores de Ciências do ensino fundamental sobre os elementos da Astronomia é o objeto de pesquisa presente neste artigo, cuja metodologia consiste em entrevistas semiestruturadas, filmadas em vídeo e centradas numa perspectiva tridimensional dos elementos astronômicos, possibilitando um mapeamento das concepções das formas e das dimensões da Terra, do Sol, da Lua, dos planetas e das estrelas, bem como da concepção de céu e de Universo como um todo. Os resultados indicam um Universo contendo: Sol, estrelas, planetas e Lua, onde o Sistema Solar é parte do todo. Algumas vezes o Universo é concebido como o próprio Sistema Solar. Os objetos estão no céu ou no Universo o qual, para muitos, se restringe ao espaço que está acima da Terra. A forma plana dos objetos astronômicos e a estrutura espacial da montagem do Universo são características marcantes. Muitos indicam Sol e estrelas como coisas diferentes: Sol é um objeto quente e as estrelas são frias. Esses resultados nos preocupam e certamente sinalizam uma urgência de programas de formação continuada para professores no conteúdo de astronomia, uma vez que os PCN´s indicam fortemente o ensino desse conteúdo.
المفردات الاصطلاحية من الكتاب "نحو ثقافة إسلامية أصيلة" لعمر سليمان الأشقر والاستفادة منها في إثراء لغة طلاب الكلية بجامعة الراية
Authors: Abdul Aziz Mufti 
Published: January 2020

This research aims to analyze and limit terms vocabularies in the book "Nahw Tsaqȃfah Islȃmiyyah Ashȋlah" by Umar Sulayman Al-Asyqar, which the book is including of materials books for PBA (Arabic Education Department) in the STIBA Ar Raayah that contains many terms vocabularies. Aside from that, this research also aims to present effective ways to utilization of those vocabularies terms to enriching the students language in STIBA Ar Raayah. This research uses descriptive methods of analysis where researcher is trying to accumulate and limit terms vocabularies of that book and then analyse it by definition them according to etymologically and terminologic. In this study, two main results achieved; the first, that terms vocabularies in the book "Nahw Tsaqȃfah Islȃmiyyah Ashȋlah" numbered fifty-one vocabulary, which can be analyzed by defining each vocabulary etymologically and terminologis. Then the second, effective ways that proposed for utilization of the vocabulary to enrich the students language the STIBA Ar Raayah is in two ways; First, by way of formulating the learning material in the form of conversation come with reserved exercises for these lessons, and in the form of text reading is also equipped with with the exercises for it. And second, by way of formulating the dictionary of terms vocabularies for the book.
النظائر المخادعة بين اللغة العربية واللغة الجاوية في تفسير الإبريز الجاوي
Authors: Hajiroh  , Huda Syirojul 
Published: January 2020

ABSTRACT
The aim of this study was to know the meaning of the homonym between Arabic and Javanese from surah Al-Fatihah to Surah Al-Baqarah verse 1-25 to encourage the Javanesse to learn Arabic and to learn Arabic and to convince was a difficult thing, as well as to make Arabic learning easier by showing them the function of this homonym. The method of this study as: the descriptive analytical method for comparing between Arabic and Javanese. The result from this study showed that there were homonym between the two languages. And from these words there were some words had the complete similarity between to phonems and some words had lack similarity between two phonems, but the words with lack similarity were much more. This study also showed that there was an effective method to learn Arabic and how to apply the fuction of the homonym from the beginners of Javanese speaking students by putting these homonyms in conversation, discourse, and the exercise. The most Important result of this study were: there were difference and similarity in the two language from Arabic and Javanese, and every words had a different meaning.
الوقف والابتداء في القرآن الكريم والاستفادة منهما في تعليم اللغة العرية في سورة ق نموذجا
Authors: HISAN QUDWATUN 
Published: January 2020

Al Waqfu and al Ibtida’ is one of important part an Arabic languistic principle that every student of Arabic language have to understand clearly. Al Waqfu wa al Ibtida’ is a principle that arrange how to stop how to begin when reading sentences. This principle is guidience that assure the student of Arabic language catching the true meaning of the Arabic text that she or he reads, especially the Qur’an text. The implemementation of this principles may lead to missunderstanding the true meaning of a text. The implementation of this principle not only critical for the reader its also critical for the listener, they also could missunderstand the meaning of the text that they hear.The aim of this study is to analyse the methods that used by the islamic scholars to build the principle, especially tht related to the Qur’anic text. Second, this study will disscus the benefit of implementation of this principle in Arabic language study. This research is based on library research and discriptive analysis.The study several that Al-Waqaf is catagorized to four category that is; perfect stop, sufficent stop, good stop, and bad stop. Al- Ibtida’ is categorized to two category that is; good begining, and bad beging in Arabic language studies this knowladge could be use as parameter to evaluate the capacibility of a student in understanding the true meaning of the text that he or she reads. And teaching Arabic could be use for four skill especially reading skill. Arabic teaching in reading skill can use reading text because it one method to identify the means where he stopped reading and it could use dialogue reading. And the teacher can use onther method for this theaching.
Clinical and Biochemical Correlations Obesity - HDL Cholesterol- Ischemic Coronary Heart Disease
Authors: Mavritsakis Nikolaos , Cotoi Bogdan Virgil , Ganescu Anca , Ionescu Elena 
Published: January 2020

Central obesity is defined by increasing abdominal circumference ranging from certain limits to the characteristics of the ethnic groups of the rated person (] 94 cm for European males and] 80 cm for Euclid women). The metabolic syndrome, commonly associated with central obesity, must meet at least two of the following four criteria:increased triglyceride levels] 159 mg / dL or specific treatment for this type of dyslipidemia; Low HDL-cholesterol [40 mg / dL or specific treatment for this type of dyslipidemia;Increased blood pressure: Systolic BP �130 mm Hg or Diastolic BP �85 mm Hg, or HTA treatment previously diagnosed;
High blood glucose level �100 mg / dL or type 2 diabetes diagnosed previously.	HDL-cholesterol (HDL-C) is a group of lipoproteinssynthesized and secreted by hepatocytes. HDL plays an important role in the metabolism of cholesterol, participating in its transport from extrahepatic tissues to the liver for catabolism and excretion.. HDL and LDL participate in maintaining cell cholesterol levels. HDL-cholesterol and apolipoprotein-A values are positive atherosclerosis risk factors. The high level of HDL-C protects the patient, with a low risk of atherosclerosis HDL dosing is done for assessing the risk of coronary artery disease; diagnosis of hyperlipoproteinemia. Increased body weight is associated with increased total mortality and morbidity due to cardiovascular disease, partly mediated by increased blood pressure and cholesterol, lowering HDL-cholesterol and increasing the likelihood of diabetes.
Pengaruh Kepemimpinan terhadap Disiplin Kerja Pegawai Kantor Kementerian Agama Kota Bukittinggi dengan Motivasi Kerja Sebagai Variabel Moderating
Authors: Suryanto Dasep 
Published: January 2020

The results showed that the influence between leadership and work discipline was significant. The influence between leadership and work motivation was also significant. The influence between work motivation cannot strengthen the leadership relationship to Work Discipline and is not significant. with a T-statistic of 1,2572541846236 (<1,960). The original sample estimate value is negative, amounting to -0.13494828, which shows that the direction of the relationship between Leadership and Work Discipline which is moderated by motivational variables has a negative and insignificant effect, while the influence between leadership and work discipline at the Office of the Ministry of Religion in Bukittinggi has a positive influence. and significant, so does the influence of leadership on motivation has a positive and significant influence and finally the influence of motivation on work discipline at the Office of the Ministry of Religion in Bukittinggi has a positive and significant effect so that all hypotheses submitted can be accepted except the leadership hypothesis in moderation of work motivation variables working discipline at the Bukittinggi City Ministry of Religion's Office is unacceptable.
Keywords: Leadership, Motivation and Discipline
PENGARUH PEMAHAMAN AKUNTANSI DAN PENERAPAN SISTEM INFORMASI KEUANGAN DAERAH TERHADAP KUALITAS LAPORAN KEUANGAN PEMERINTAH DAERAH DENGAN KOMPETENSI SUMBER DAYA MANUSIA SEBAGAI VARIABEL MODERASI (STUDI EMPIRIS PADA PEMERINTAH KOTA PEKANBARU)
Authors: Yeni Elfita , Irman Mimelientesa , Fadrul Fadrul 
Published: January 2020

This study aims to determine the influence of Accounting Understanding an Application, financial accounting systems human resource competency on the quality of regional financial statement. Based on PP No. 71 year 2010, state and local government financial statement quality have to meet the qualitative characteristic. Factors examined include Acounting understanding, human resource competency financial accounting system and the quality of regional financial statement. The used sampling method is purposive sampling sampling. Data collection is done by giving as many as 90 copies, copies of the questionnaire,which was distributed to respondents who are staff financial in Pekanbaru City. The Data obtained are then analyzed using SPSS 21.00. Based on the analysis results, obtained that applicatin of Accounting and the financial accounting systems have a positive and significant effect to the quality of financial reporting information in OPD Pekanbaru City and human resource competency can be used as a moderating variable.
DUST MITIGATION EMPLOYING A PROGRAM BASED APPROACH
Authors: Clark Steven R. 
Published: January 2020

INTRODUCTION Of all the natural resources being taxed by the needs of the mining and oil & gas industries, possibly the most important is the expanding demand for water resources. As water becomes scarcer, and increasingly important, new technologies are needed to find innovative ways to preserve this precious resource. In Chile, for example, the mining industry is investing billions of dollars to build desalination plants and pipelines; bringing ocean water as far as 200 kilometers inland to meet demand and maintain operations. It is a wide-ranging crisis for that nation and a top priority for their government and economy. It has been reported that water managers in 40 states expect water shortages in some portion of their states in the next 10 years.1 In the U.S., as more and more communities continue to be built, greater requirements on the current water infrastructure is generated. Water demand is projected to increase by 55% globally between 2000 and 2050. The increase in demand will come mainly from manufacturing (+400%), electricity (+140%) and domestic use (+130%). In the face of these competing demands, there will be little scope for increasing water for irrigation.2 For 25 percent of people and operations that rely on water from aquifers, this source is being consumed at a rate that will create significant problems meeting the demand in as few as two generations.3 There are three major areas of water usage for dust control in mining and oil & gas industries: material handling (process), non-traffic areas (wind erosion), and traffic areas (roads and large surfaces). Each of these areas could have an article dedicated to dust mitigation solutions; however, the one area that all mine and oil & gas facilities have in common is the unpaved haul road and light vehicle access road. This article will focus on controlling dust on the drivable surface and will show that implementing a dust mitigation program will not only save water resources, but also can become a source for expense savings.
Evidence-Based Review and Discussion Points
Authors: Horn Kimberly , Dino Geri , Hamilton Candice , Noerachmanto N. , Zhang Jianjun 
Published: January 2020

Background Traditional efficacy research alone is insufficient to move interventions from research to practice. Motivational interviewing has been adapted for brief encounters in a variety of health care settings for numerous problem behaviors among adolescents and adults. Some experts suggest that motivational interviewing can support a population health approach to reach large numbers of teen smokers without the resource demands of multisession interventions.
Objectives To determine the reach, implementation fidelity, and acceptability of a brief motivational tobacco intervention for teens who had treatment in a hospital emergency department.
Methods Among 74 teens 14 to 19 years old, 40 received a brief motivational tobacco intervention and 34 received brief advice/care as usual at baseline. Follow-up data were collected from the interventional group at 1, 3, and 6 months and from the control group at 6 months. For the interventional group, data also were collected from the teens’ parents, the health care personnel who provided the intervention, and emergency department personnel.
Results Findings indicated low levels of reach, high levels of implementation fidelity, and high levels of acceptability for teen patients, their parents, and emergency department personnel. Data suggest that practitioners can operationalize motivational interventions as planned in a clinical setting and that patients and others with an interest in the outcomes may find the interventions acceptable. However, issues of reach may hinder use of the intervention among teens in clinical settings.
Conclusions Further investigation is needed on mechanisms to reduce barriers to participation, especially barriers related to patient acuity.
Predictors of Adverse Events in Patients After Discharge From the Intensive Care Unit
Authors: Chaboyer Wendy , Thalib Lukman , Foster Michelle , Ball Carol , Richards Brent 
Published: January 2020

Background Patients discharged from the intensive care unit may be at risk of adverse events because of complex care needs.
Objective To identify the types, frequency, and predictors of adverse events that occur in the 72 hours after discharge from an intensive care unit when no evidence of adverse events was apparent before discharge.
Methods A predictive cohort study of 300 patients from an adult intensive care unit was undertaken. An internationally accepted protocol for chart audit was used. Frequency of adverse events was calculated, and logistic regression was used to determine independent predictors of adverse events.
Results A total of 147 adverse events, 17 (11.6%) of which were defined as major, were incurred by 92 patients (30.7%). The 3 most common adverse events, hospital-incurred infection or sepsis (n = 32, 21.8%), hospital-incurred accident or injury (n = 17, 11.6%), and other complication such as deep vein thrombosis, pulmonary edema, or myocardial infarction (n = 17, 11.6%) accounted for 44.9% (n = 66) of all adverse events. Two predictors, respiratory rate less than 10/min or greater than or equal to 25/min and pulse rate exceeding 110/min, were significant independent predictors; requiring a high level of nursing care at the time of discharge was a significant predictor in univariate analysis but not in multivariate analysis.
Conclusion Taking, recording, and reporting vital signs are important. Nursing care requirements of patients at discharge from the intensive care unit may be worthy of further investigation in studies of patients after discharge.
Blockade of N-Glycosylation Promotes Antitumor Immune Response of T Cells
Authors: Sasawatari Shigemi , Okamoto Yuki , Kumanogoh Atsushi , Toyofuku Toshihiko 
Published: January 2020

Abstract
Adoptive cellular therapy and its derivative, chimeric AgR T cell therapy, have achieved significant progress against cancer. Major barriers persist, however, including insufficient induction of cytotoxic T cells and exhaustion of tumor-infiltrating lymphocytes. In this study, we discovered a new role for 2-deoxy-d-glucose (2DG) in enhancing the antitumor activity of human T cells against NKG2D ligand-expressing tumor cells. Human T cells treated with 2DG upregulated the NK-specific transcription factors TOX2 and EOMES, thereby acquiring NK cell properties, including high levels of perforin/granzyme and increased sensitivity to IL-2. Notably, rather than inhibiting glycolysis, 2DG modified N-glycosylation, which augmented antitumor activity and cell surface retention of IL-2R of T cells. Moreover, 2DG treatment prevented T cells from binding to galectin-3, a potent tumor Ag associated with T cell anergy. Our results, therefore, suggest that modifying N-glycosylation of T cells with 2DG could improve the efficacy of T cell–based immunotherapies against cancer.