bluuebunny/crossref_metadata_2025_split huggingface dataset:
Christ's Love as the Basis of the Church's Faith Witness to Muslims
Authors: Wrogemann Henning 
Published: November 2020

AbstractAccording to the Christian view, the essence of the triune God is revealed in the relational event between God the Father, the Son Jesus Christ, and the Holy Spirit. The Bible says of this God, “God is love” (1 John 4:8, 16). By way of example, the article explores “God's love” to show that the Qur'an's conception of God is incompatible with key tenets of the New Testament. Thus, when keeping both conceptions of God in view, we cannot speak of one and the same God. Now what does this mean for the pursuit of conciliatory relations between Christians and Muslims? Which relational paradigms need to be kept in mind?After reflecting on the concepts of neighbourliness, companionship, and hospitality, the article goes on to trace the conceptual outlines of Christian mission as a mission of God's love (missio amoris Dei). Its hypothesis is that a characteristically Christian conception of God can supply useful motifs for appreciative and conciliatory actions by Christians toward Muslims. Finally, the author proposes a theology of interreligious relations (which he has elaborated upon elsewhere) as an alternative approach to conventional theologies of religion.
Quantifying individual and interactive effects of elevated temperature and drought stress on cotton yield and fibre quality
Authors: Gao Min , Xu Bingjie , Wang Youhua , Zhou Zhiguo , Hu Wei 
Published: November 2020

AbstractThe individual effect of high temperatures or water‐deficit stress on cotton has been studied extensively; however, their combined effects were less studied. To that end, an experiment was imposed with a heat‐sensitive (Sumian 15) and a heat‐tolerant (PHY370WR) cultivar in 2016–2018 and two temperature regimes including ambient temperature (AT, 31.0/26.4°C) and elevated temperature (ET, 33.4/28.9°C), and three soil relative water content (SRWC) levels including (75 ± 5)%, (60 ± 5)% and (45 ± 5)% were performed. Results showed that the decline in boll number was the primary driver of yield loss, while the decreases in boll weight minimally impacted yield under drought and combined treatments. Besides, elevated temperature and drought stress performed significant interactions on boll weight (except in 2018) and seed cotton yield (except for Sumian 15 in 2017). Specifically, seed cotton yield was reduced by 23%–35% in Sumian 15 and by 8%–13% in PHY370WR under ET60(ET with SRWC (60 ± 5)%), while the reduction was 44%–54% in Sumian 15 and 37%–43% in PHY370WR under ET45(ET with SRWC (45 ± 5)%), which produced lower yields than any other treatment combination or any single abiotic stress factor. Furthermore, significant interactions between the two stresses were observed in fibre length of Sumian 15 and strength (except for PHY370WR in 2018) and micronaire (except for Sumian 15 in 2017 and for PHY370WR in 2018) of both cultivars. Elevated temperature exacerbated the negative impacts of drought on fibre length but offset them on fibre strength and micronaire. Finally, the economic benefit among different treatments was evaluated. Compared to the control, ET45suffered the biggest economic loss by 2,536.7 USD ha−2in Sumian 15 and by 2,167.8 USD ha−2in PHY370WR, respectively. Quantifying the interactive effects of drought and elevated temperature on cotton yield and fibre quality should allow researchers to better understand the economic implications of these two stresses which often occur concurrently under field conditions.
Feeling of grief and loss in parental caregivers of adults diagnosed with intellectual disability
Authors: Fernández‐Ávalos María Inmaculada , Pérez‐Marfil María Nieves , Ferrer‐Cascales Rosario , Cruz‐Quintana Francisco , Fernández‐Alcántara Manuel 
Published: November 2020

AbstractBackgroundThe diagnosis of intellectual disability in children can produce complex grief‐related feelings in their parents. Previous studies have focused on the moment of the diagnosis or the early life of the children, and little research has been conducted on their feelings of grief in adulthood. The objective was to analyse the process of grief/loss in parents of adult offspring with intellectual disability.MethodThe intentional sampling included sixteen parents who responded to semi‐structured interviews. A qualitative study was conducted based on grounded theory.ResultsFive categories were identified: “Reception of the diagnosis”, “Emotional bonds with the child”, “Experience of loss and feelings in response to intellectual disability diagnosis”, “Recurrent grief” and “Coping strategies”.ConclusionsRecurring feelings of loss experienced by parents in relation to their child's diagnosis persist over time. Specialized emotional interventions are needed to help parents to reduce the intensity of their feelings of grief.
Kids helping kids: The lived experience of adolescents who support friends with mental health needs
Authors: Roach Ashley , Thomas Sandra P. , Abdoli Samereh , Wright Megan , Yates Andria L. 
Published: November 2020

AbstractProblemAdolescent mental health is a significant health care issue. Friends play an important role in the lives of adolescents with mental health concerns and help to improve outcomes related to depression and suicide. However, little is known about the experiences of adolescents who help their friends with these concerns.MethodsA phenomenological research design involving unstructured interviews was used to answer the question: what is the lived experience of adolescents who provide support to friends with anxiety, depression, or who express suicidal ideation?” Participants for this study were aged 16–17 and included both males (n = 2) and females (n = 3).FindingsParticipants described their experience as “Kids Helping Kids” which is defined by the following themes: Being Fearful, Maintaining Vigilance, Seeking Knowledge, Keeping Secrets, Involving Others, Setting Boundaries, and Feeling Honored.ConclusionHelping a friend with mental health concerns can be challenging yet rewarding. Nurses should be aware of this role that some adolescents undertake and include the friends of adolescents with mental health concerns as part of plans of care.
Analysis of the development and structural drivers of raw‐material use in Germany
Authors: Pfaff Matthias , Walz Rainer 
Published: November 2020

AbstractIn orderto reduce the negative consequences of raw‐material extraction, it is necessary to accurately report raw‐material use and to understand its drivers in society. In this study, we conduct a multi‐regional environmentally extended input–output analysis of Germany's past raw‐material use. We then perform a two‐stage structural decomposition analysis (SDA) of the development of material use in order to identify the main drivers. Although input‐based indicators of Germany's raw‐material use, which also include the material footprint of exports, show slight upward trends between 1995 and 2011, consumption‐based indicators have remained relatively steady in that time frame. On the one hand, this suggests a relative decoupling of Germany's domestic consumption from material use. On the other hand, exports, which contribute significantly to Germany's value‐added creation, have driven up input‐based indicators. The first stage of the SDA reveals that the material intensity of raw‐material provision would have by itself decreased Germany's raw‐material consumption (RMC), whereas changes in the structure of the global economy and in Germany's final demand would have increased it. The second stage of the decomposition reveals that the positive contributions to Germany's RMC are in large part due to shifts toward internationally sourced intermediate and final goods and an overall increase in the level of final demand in Germany.
Vertical or horizontal scalp mobility: What to assess
Authors: Mohmand Mohammad Humayun , Ahmad Muhammad 
Published: November 2020

AbstractBackgroundScalp is comprised of five layers namely skin, connective tissue, aponeurosis, loose areolar tissue, and periosteum, each having distinct characteristics. The scalp mobility plays an important role in scalp wound closure. Thus, the estimation of scalp mobility is necessary to obtain a tension‐free closure and fine scar in hair restoration surgery.AimsTo know the difference of available number of FUs while using two different scalp mobility methods, that is, horizontal vs vertical methods.Patients/MethodsThe study was conducted in a private hair restoration clinic in the patients undergoing surgery after taking informed consent from all the patients. Any patient with a previous scalp surgery was excluded. The horizontal mobility was calculated using Mayer’s method, and the vertical mobility was calculated using Mohmand 7 Ahmad’s method on the same areas. All the data were recorded and analyzed statistically using Mann‐Whitney test.ResultsA total of 15 patients were included in the study. The average length of the strip was 24.7 cm (range; 20‐29 cm) with hair density of 138.1 cm2 (range; 114‐195.7 cm2). The average strip width was found to be 17.1 mm by using horizontal mobility scale and 19.6 mm by using vertical scalp mobility. The horizontal scale resulted in average strip area of 42.0 cm2 as compared to average area of 49.1 cm2 by using vertical scale. The average number of hair by horizontal scale was calculated to be 5792.8 hairs and 6762.5 hairs by using vertical mobility scale (P < .05). The average number of more hair to be available by using vertical scale was 969.7.ConclusionThe vertical scale resulted in more number of hair from the donor strip in the same patient.
Cervical Carotid Artery Dolichoectasia as a Marker of Increased Vascular Risk
Authors: Khasiyev Farid , Gutierrez Jose 
Published: November 2020

ABSTRACTCervical carotid artery (cCA) dolichoectasia (DE) is characterized by elongation, tortuosity, and/or dilatation. The prevalence of cCA DE has been reported 13‐31% in population‐based and 14‐58% in hospital‐based studies. The exact mechanisms of this aberrant arterial remodeling are unknown. Although atherosclerosis has often been implicated, the evidence has conflicting results that would support atherosclerosis as the underlying pathology. Actually, other nonatherosclerotic mechanisms related to connective tissue remodeling may play a role. Such mechanism is supported by epidemiological evidence that cCA DE is associated with carotid dissections. Similarly, cCA DE has been associated with vascular risk factors, but inconsistently. Fewer studies have evaluated the risk of vascular events in people with cCA DE. Cross‐sectionally, cCA DE is associated with cerebrovascular disease, including white matter hyperintensities, lacunar stroke, and stroke overall. The often‐conflicting results may in part be due to the heterogeneity of the population studies and variable definitions used. Preferential use of objective measure of cCA DE, such as carotid length, is advisable, and may help comparing result among different studies. Prospectively, people with cCA DE have a higher risk of vascular events, although it is uncertain if the risk of stroke is also higher in this population. In the absence of alternative stroke etiologies, stroke patients with cCA DE should be considered to have had a cryptogenic stroke and treated with daily antiplatelet therapy. Further population‐based studies are needed to clarify whether specific therapies may be implement to reduce the risk of events among people with cCA DE.
Melanocytic tumours of the nasal planum in cats: 10 cases (2004–2019)
Authors: Reck A. , Kessler M. 
Published: November 2020

ObjectivesTo better characterise signalment, biologic behaviour, and treatment outcome in melanocytic tumours of the nasal planum in cats.Materials and MethodsRetrospective study in cats diagnosed with histopathologically confirmed melanocytic tumours on the nasal planum.ResultsTen cats were identified with melanocytic tumours of the nasal planum. Pigmentation of the nasal planum seemed to be a predisposing factor. Seven cats were diagnosed histopathologically with a malignant melanoma, three with a benign melanocytoma. One of the cats developed a lymph node metastasis despite diagnosis of a well‐differentiated melanocytic neoplasia. In four cases, a pigmented mass, which was initially stable over a long time, showed a sudden rapid progression suggesting malignant transformation. Treatments included hypofractionated radiation therapy (n = 6) and surgical resection (n = 1). In three cats no further treatment was pursued. Complete (n = 3) and partial (n = 3) remissions were observed in cats treated with radiation therapy; however, all experienced tumour progression or recurrence after a short period of time. Most of the cats (n = 7) had to be euthanased due to tumour progression (median survival time: 265 days).Clinical SignificanceThe present case series provides insights in clinical presentation and clinical outcomes of cats with melanocytic tumours of the nasal planum.
Identifying Children with Persistent Developmental Dyscalculia from a 2‐min Test of Symbolic and Nonsymbolic Numerical Magnitude Processing
Authors: Bugden S. , Peters L. , Nosworthy N. , Archibald L. , Ansari D. 
Published: November 2020

ABSTRACTDevelopmental dyscalculia (DD) is a mathematical learning disability that occurs in around 5%–7% of the population. At present, there are only a handful of screening tools to identify children that might be at risk of developing DD. The present study evaluated the classification accuracy of one such tool: The Numeracy Screener, a 2‐min test of symbolic (Arabic numerals) and nonsymbolic (dot arrays) discrimination ability. A sample of 222 children who demonstrated persistent deficits (n = 55), inconsistent deficits (n = 51), or typical performance (n = 116) on standardized tests of math achievement over multiple observations was tested. The Numeracy Screener correctly classified children in all three groups. Notably, the symbolic condition has greater sensitivity in discriminating children with persistent DD from the other two groups. Screening tools that assess early numeracy skills may be promising for identifying children at risk for developing severe mathematical difficulties.
The conserved aromatic residue W122 is a determinant of potyviral coat protein stability, replication, and cell‐to‐cell movement in plants
Authors: Yan Zhi‐Yong , Cheng De‐Jie , Liu Ling‐Zhi , Geng Chao , Tian Yan‐Ping , Li Xiang‐Dong , Valkonen Jari P. T. 
Published: November 2020

AbstractCoat proteins (CPs) play critical roles in potyvirus cell‐to‐cell movement. However, the underlying mechanism controlling them remains unclear. Here, we show that substitutions of alanine, glutamic acid, or lysine for the conserved residue tryptophan at position 122 (W122) in tobacco vein banding mosaic virus (TVBMV) CP abolished virus cell‐to‐cell movement in Nicotiana benthamiana plants. In agroinfiltrated N. benthamiana leaf patches, both the CP and RNA accumulation levels of three W122 mutant viruses were significantly reduced compared with those of wild‐type TVBMV, and CP accumulated to a low level similar to that of a replication‐deficient mutant. The results of polyprotein transient expression experiments indicated that CP instability was responsible for the significantly low CP accumulation levels of the three W122 mutant viruses. The substitution of W122 did not affect CP plasmodesmata localization or virus particle formation; however, the substitution significantly reduced the number of virus particles. The wild‐type TVBMV CP could complement the reduced replication and abolished cell‐to‐cell movement of the mutant viruses. When the codon for W122 was mutated to that for a different aromatic residue, phenylalanine or tyrosine, the resultant mutant viruses moved systemically and accumulated up to 80% of the wild‐type TVBMV level. Similar results were obtained for the corresponding amino acids of W122 in the watermelon mosaic virus and potato virus Y CPs. Therefore, we conclude that the aromatic ring in W122 in the core domain of the potyviral CP is critical for cell‐to‐cell movement through the effects on CP stability and viral replication.
miR169c‐NFYA‐C‐ENOD40 modulates nitrogen inhibitory effects in soybean nodulation
Authors: Xu Hanyu , Li Yanjun , Zhang Kefei , Li Mingjia , Fu Siyuan , Tian Yingzhe , Qin Tongfei , Li Xinxin , Zhong Yongjia , Liao Hong 
Published: November 2020

Summary

Legume crops contribute a great portion of clean nitrogen (N) to agro‐ecosystems through symbiotic N2 fixation in the nodule; however, the nodulation is always inhibited by high N availability which is known as the N inhibitory effect through largely unknown mechanisms.

We functionally investigated miR169c‐GmNFYA‐C‐GmENOD40 under multiple N conditions in soybean (Glycine max) (ENOD, Early Nodulin; NFYA, Nuclear Factor‐Y Subunit A). We elucidated their regulatory roles in soybean nodulation through analyzing expression patterns, micro–messenger RNA (miRNA–mRNA) interactions, phenotypes of transgenic soybean plants and genetic interactions.

We found that miR169c expression was induced by high N, whereas its target GmNFYA‐C was preferentially expressed in nodules and induced by rhizobium inoculation. Overexpression of miR169c inhibited nodulation through targeting 3′‐UTR of GmNFYA‐C, whereas knockout miR169c through CRISPR‐cas9 promoted nodulation. However, overexpression of GmNFYA‐C promoted soybean nodulation through facilitating rhizobium infection and increasing the expression of symbiotic signaling gene GmENOD40. Besides, GmNFYA‐C directly induced the expression of GmENOD40. In addition, overexpression of GmNFYA‐C without the target site of miR169c partially attenuated the inhibitory effect of high N on soybean nodulation.

We discovered a new regulatory pathway involving the miR169c‐NFYA‐C‐ENOD40 module that regulates soybean nodulation in response to N availability. This pathway provides substantial new insights into the mechanisms underlying the N inhibitory effect on nodulation.
Cycling and how to study it: Looking at the New Zealand case
Authors: Latham Alan 
Published: November 2020

AbstractCycling has the potential to play a key role in developing environmentally and socially sustainable cities and neighbourhoods in New Zealand. Realising this potential requires understanding how different groups within New Zealand society relate to existing patterns of cycling, and how they might respond to the introduction of a range of new cycling oriented infrastructures. Commenting on articles from the special issue “New research on cycling in New Zealand,” this article argues that human geographers and other social scientists have much to offer policy makers and planners in understanding how a transition to more people oriented, sustainable, urban mobility systems might be fostered.
Adaptive variation and plasticity in non‐structural carbohydrate storage in a temperate tree species
Authors: Blumstein Meghan , Hopkins Robin 
Published: November 2020

AbstractTrees' total amount of non‐structural carbohydrate (NSC) stores and the proportion of these stores residing as insoluble starch are vital traits for individuals living in variable environments. However, our understanding of how stores vary in response to environmental stress is poorly understood as the genetic component of storage is rarely accounted for in studies. Here, we quantified variation in NSC traits in branch samples taken from over 600 clonally transplanted black cottonwood (Populus trichocarpa) trees grown in two common gardens. We found heritable variation in both total NSC stores and the proportion of stores in starch (H2TNC = 0.19, H2PropStarch = 0.31), indicating a substantial genetic component of variation. In addition, we found high amounts of plasticity in both traits in response to cold temperatures and significant genotype‐by‐environment (GxE) interactions in the total amount of NSC stored (54% of P is GxE). This finding of high GxE indicates extensive variation across trees in their response to environment, which may explain why previous studies of carbohydrate stores' responses to stress have failed to converge on a consistent pattern. Overall, we found high amounts of environmental and genetic variation in NSC storage concentrations, which may bolster species against future climate change.
The impact of HIV on hepatocellular cancer survival in Nigeria
Authors: Okeke E. , Mark Davwar P. , Mullen B. , Duguru M. , Agbaji O. , Sagay A. , Murphy R. , Hawkins C. 
Published: November 2020

AbstractBackgroundHepatocellular carcinoma (HCC) is an increasing cause of mortality in HIV‐infected individuals. We compared host and tumour characteristics between HIV‐infected and HIV‐uninfected Nigerians with HCC and examined the impact of HIV on survival.MethodsThis prospective observational study was conducted at Jos University Teaching Hospital in Jos, Nigeria, among adults (>18 years) with HCC enrolled between September 2015 and September 2017 and followed until April 2019. Demographics, tumour characteristics and survival were compared between HCC subjects with and without HIV.Results101 (10 HIV‐infected and 91 HIV‐uninfected) subjects were enrolled [male 72%; median age 48 (IQR 35–60)]. 60% HIV‐infected subjects were receiving ART; 90% had CD4 counts ≥ 200/mm3 at HCC diagnosis, and 20% had HIV RNA levels < 20 copies/mL. 57.4% were infected with chronic HBV (HBsAg+). The duration of symptoms was shorter in HIV‐infected vs. HIV‐uninfected subjects [93 (IQR 54–132) vs. 155 (93–248] days; p = 0.02]. At the end of follow‐up, 99 of 101 (98.0%) subjects were confirmed to have died: 9 of 10 (90.0%) HIV‐infected and 90 of 91 (98.9%) HIV‐uninfected. The probability of survival at three months was 22% and 47% in HIV‐infected and HIV‐uninfected subjects, respectively (P = 0.02). Median time to death was significantly shorter in HIV‐infected vs. HIV‐uninfected subjects [24 days (IQR 16–88) vs. 85 days (IQR 34–178), respectively (P = 0.03)].ConclusionsHigh early mortality was observed in this cohort of Nigerian adults with HCC. HIV infection was associated with a faster clinical presentation and shorter survival. More aggressive HCC surveillance may be warranted in HIV‐infected subjects, particularly if they are co‐infected with chronic HBV.
Mobilization characteristics, blood graft composition, and outcome in diffuse large B‐cell lymphoma after autologous stem cell transplantation: Results from the prospective multicenter GOA study
Authors: Partanen Anu , Turunen Antti , Valtola Jaakko , Pyörälä Marja , Vasala Kaija , Kuittinen Outi , Kuitunen Hanne , Penttilä Karri , Keskinen Leena , Kuittinen Taru , Mäntymaa Pentti , Pelkonen Jukka , Varmavuo Ville , Jantunen Esa 
Published: November 2020

AbstractBackgroundDiffuse large B‐cell lymphoma (DLBCL) is a common indication for autologous stem cell transplantation (auto‐SCT).Study Design and MethodsThis prospective noninterventional study aimed to evaluate the impact of mobilization characteristics and graft cellular content on hematologic recovery and outcome after auto‐SCT among 68 patients with DLBCL.ResultsBetter mobilization capacity as manifested by blood CD34+ cell count >32 × 106/L and CD34+ cell yield of the first apheresis >2.75 × 106/kg correlated with faster neutrophil (P = .005 and P = .017) and platelet (P = .002 and P < .001) recovery. A higher number of infused CD34+ cells (> 2.65 × 106/kg) was associated with better 5‐year overall survival (OS; 95% vs 67%, P = .012). The graft CD34+CD133+CD38− cell count >0.07 × 106/kg was predictive of better 5‐year OS (87% vs 63%; P = .008) and higher graft CD3+ cell count (>23.1 × 106/kg) correlated also with better 5‐year OS (80% vs 40%, P = .008). In multivariate analysis only disease status of CR I at auto‐SCT was associated with better progression‐free survival (P = .014) and OS (P = .039).ConclusionThe mobilization capacity of CD34+ cells impacted on early hematologic recovery in patients with DLBCL after auto‐SCT. Higher graft CD34+ cell count and both CD34+CD133+CD38− and CD3+ cells were also associated with better OS. The effect of optimal graft cellular composition on outcome in DLBCL should be evaluated in a randomized study.