bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance-approach goals: the operationalization makes the difference
Authors: Wirthwein Linda , Steinmayr Ricarda 
Published: December 2020

AbstractThe operationalization of performance-approach goals (PAGs) was found to be an important moderator of the associations between different PAGs and several educational outcomes. To explore this aspect in more detail, we conducted two studies with school students (N1 = 425, mean age = 16.6 years, SD = 0.61; N2 = 310, mean age = 14.91, SD = 1.72). In study 1, we mainly focused on the associations between achievement goals and school grades. In study 2, we additionally assessed several motivational variables (academic self-concept, school values), as well as test anxiety and school well-being. All variables were assessed for school in general, mathematics, and German (mother tongue). The results of confirmatory factor analyses replicated and extended the finding on the different facets of PAGs. Besides a normative-based PAG component (the aim is to perform better than others) and an appearance-based PAG component (the aim is to demonstrate one’s ability), an additional proving PAG component (the aim is to demonstrate one’s ability toward significant others) was found. Contrary to earlier findings, both normative and appearance-based PAGs were positively correlated with school grades, whereas the proving component showed smaller associations. Moreover, differential associations with self-concept, school values, and school well-being emerged regarding the different facets of PAGs. The results are discussed with regard to the operationalization of PAGs.
Plant invasion as an emerging challenge for the conservation of heritage sites: the spread of ornamental trees on ancient monuments in Rome, Italy
Authors: Celesti-Grapow Laura , Ricotta Carlo 
Published: December 2020

AbstractCultural heritage sites such as historical or sacred areas provide suitable habitats for plants and play an important role in nature conservation, particularly in human-modified contexts such as urban environments. However, such sites also provide opportunities for the spread of invasive species, whose impact on monuments has been raising growing concerns. The aim of this study was to investigate the patterns of distribution and spread of invasive plants in heritage areas, taking the city of Rome as an example. We focused on woody species as they pose the greatest threat to the conservation of monuments, owing to the detrimental effects of their root system. We analysed changes in the diversity and traits of native and non-native flora growing on the walls of 26 ancient sites that have been surveyed repeatedly since the 1940s. We found that the diversity of the native flora has steadily decreased, while there has been an increase in non-native, larger and more damaging species. The introduced species that have expanded most are ornamental wind- or bird-dispersed trees, which represent a major management problem as their propagules can reach the upper sections of the monuments, where they become more difficult to control. The most widespread and damaging of such species is Ailanthus altissima, which has recently been included among the invasive species of European Union concern (EU Regulation 2019/1262). Our findings show that plant invasion is an emerging challenge for the conservation of heritage sites and needs to be prioritized for management to prevent future expansion.
Pemafibrate prevents retinal neuronal cell death in NMDA-induced excitotoxicity via inhibition of p-c-Jun expression
Authors: Fujita Naoki , Sase Kana , Tsukahara Chihiro , Arizono Ibuki , Takagi Hitoshi , Kitaoka Yasushi 
Published: December 2020

AbstractExcitotoxicity is involved in the retinal neuronal cell death in diabetic retinopathy. Although fenofibrate has been shown to ameliorate the progression of diabetic retinopathy, the effect of pemafibrate, which is highly selective for peroxisome proliferator-activated receptor α on retinal neuronal cell death has not been documented. Here, we investigated whether pemafibrate exerts a beneficial effect against retinal ganglion cell (RGC) death induced by N-methyl-D-aspartate (NMDA) in rats. Experiments were performed on adult male Wistar rats that received an intravitreal injection of 20 nmol NMDA. Fluoro-Gold labeled RGC morphometry showed that oral intake of pemafibrate once a day for 7 days resulted in significant protection on RGC death induced by NMDA. Phosphorylated c-Jun protein, which is involved in apoptosis, was upregulated after NMDA exposure, and this increase was significantly lessened by the systemic pemafibrate treatment. Phosphorylated c-Jun immunopositive cells were colocalized with Thy-1 immunopositive cells, and the increased these cells were ameliorated by the pemafibrate treatment. An increase in TUNEL-positive cells was significantly suppressed by the pemafibrate treatment. Phosphorylated c-Jun immunopositive cells were colocalized with TUNEL-positive cells, and they were decreased by pemafibrate treatment. These results suggest that the RGC protection achieved with pemafibrate appears to be associated with inhibition of phosphorylated c-Jun and its anti-apoptotic effect.
High-Temperature Oxidation in Dry and Humid Atmospheres of the Equiatomic CrMnFeCoNi and CrCoNi High- and Medium-Entropy Alloys
Authors: Stephan-Scherb Christiane , Schulz Wencke , Schneider Mike , Karafiludis Stephanos , Laplanche Guillaume 
Published: December 2020

Abstract
Surface degradation phenomena of two model equiatomic alloys from the CrMnFeCoNi alloy system were investigated in 2% O2 and 10% H2O (pO2 = 0.02 and 10−7 atm, respectively) at 800 °C for times up to 96 h. The crystallographic structures, morphologies, and chemical compositions of the corrosion layers developing on CrMnFeCoNi and CrCoNi were comparatively analyzed by mass gain analysis, X-ray diffraction, and scanning electron microscopy combined with energy-dispersive X-ray spectroscopy and electron backscatter diffraction. The oxidation resistance of CrMnFeCoNi is relatively poor due to the fast growth of porous Mn-oxide(s). CrCoNi forms an external chromia layer that is dense and continuous in a dry 2% O2 atmosphere. This layer buckles and spalls off after exposure to 10% H2O atmosphere. Beneath the chromia layer, a Cr-depleted zone forms in the CrCoNi alloy in both environments. As the oxide scale spalls off in the H2O-containing atmosphere, a secondary chromia layer was observed and correspondingly enlarges the Cr-depleted zone. In contrast, as the chromia layer remains without significant spallation when CrCoNi is exposed to a dry oxidizing atmosphere, the region depleted in Cr is narrower.

Graphic Abstract
Space Invaders: Pedestrian Proxemic Utility Functions and Trust Zones for Autonomous Vehicle Interactions
Authors: Camara Fanta , Fox Charles 
Published: December 2020

AbstractUnderstanding pedestrian proxemic utility and trust will help autonomous vehicles to plan and control interactions with pedestrians more safely and efficiently. When pedestrians cross the road in front of human-driven vehicles, the two agents use knowledge of each other’s preferences to negotiate and to determine who will yield to the other. Autonomous vehicles will require similar understandings, but previous work has shown a need for them to be provided in the form of continuous proxemic utility functions, which are not available from previous proxemics studies based on Hall’s discrete zones. To fill this gap, a new Bayesian method to infer continuous pedestrian proxemic utility functions is proposed, and related to a new definition of ‘physical trust requirement’ (PTR) for road-crossing scenarios. The method is validated on simulation data then its parameters are inferred empirically from two public datasets. Results show that pedestrian proxemic utility is best described by a hyperbolic function, and that trust by the pedestrian is required in a discrete ‘trust zone’ which emerges naturally from simple physics. The PTR concept is then shown to be capable of generating and explaining the empirically observed zone sizes of Hall’s discrete theory of proxemics.
Source of strontium in archaeological mobility studies—marine diet contribution to the isotopic composition
Authors: Lahtinen Maria , Arppe Laura , Nowell Geoff 
Published: December 2020

AbstractThe strontium isotope composition of human tissues is widely used in archaeological mobility studies. However, little attention is paid to the relative contributions of terrestrial versus marine sources of strontium in these studies. There is some debate over the role of a solid diet versus drinking water as the most important source of strontium for the human body, with related possibilities of misinterpretation of the archaeological record if only strontium isotope compositions of the biosphere are studied. However, there is a third component, marine strontium, which is commonly not assumed to contribute towards the strontium isotope composition of archaeological skeletal remains, especially in locations that are not directly coastal. To illustrate the potentially obfuscating effects of mixed Sr sources in a human population, we present a case study of twelve individuals from the medieval Finnish site Iin Hamina with a known dietary history. Our study shows that marine consumption is a significant factor explaining the strontium isotope composition of the Iin Hamina human remains, with implication of erroneous conclusions about immigration without prior knowledge of diet composition. Thus, future studies should always incorporate a rigorous analysis of dietary history, with special regard to potential consumption of aquatic resources, when strontium isotope analysis is used as a method in the study of palaeomobility.
Winter activity unrelated to introgression in British bumblebee Bombus terrestris audax
Authors: Hart Alex F. , Maebe Kevin , Brown Gordon , Smagghe Guy , Ings Thomas 
Published: December 2020

AbstractBombus terrestrisis a bumblebee with a wide geographic range, with subspecies showing a variety of local adaptations. Global export of commercially-rearedB. terrestrisstarted in the 1980s; the bees are a mixture of subspecies bred for ease of rearing, bivoltinism and large nests. This paper investigated whether the increase in bivoltinism in UK residentB. terrestris audaxpopulations was related to introgression with imported foreign subspecies. Workers were collected from wild populations in London and Bristol, as well as two commercial suppliers. Fourteen microsatellite loci were used to study population structure, hybridisation and introgression. No introgression with commercialB. t. dalmatinuswas detected in wild populations. Hence, the increase in winter activity appears unrelated to introgression.
The impact of dental caries and its treatment under general anaesthetic on children and their families
Authors: Knapp R. , Marshman Z. , Gilchrist F. , Rodd H. 
Published: December 2020

AbstractObjectiveTo assess the impact of dental caries and treatment under general anaesthetic (GA) on the everyday lives of children and their families, using child-reported measures of quality of life (QoL) and oral health-related quality of life (OHRQoL).MethodParticipants, aged 5–16 years old having treatment for dental caries under GA, were recruited from new patient clinics at Charles Clifford Dental Hospital, Sheffield. OHRQoL was measured before and 3-months after treatment using the Caries Impacts and Experiences Questionnaire for Children (CARIES-QC). Overall QoL was measured using the Child Health Utility 9D (CHU9D). Parents/caregivers completed the Family Impact Scale (FIS).ResultsEighty five parent–child dyads completed the study. There was statistically significant improvement in OHRQoL (mean interval score difference in CARIES-QC = 4.43,p < 0.001) and QoL (mean score difference in CHU9D = 2.48,p < 0.001) following treatment, with moderate to large effect sizes. There was statistically significant improvement in FIS scores (mean score difference = 5.48,p = 0.03).ConclusionsTreatment under GA was associated with improvement in QoL and OHRQoL as reported by children, and reduced impacts on the family. This work highlights the importance of GA services in reducing the caries-related impacts experienced by children. Further work is needed investigate the impact of clinical, environmental and individual factors.
Body appreciation and appearance evaluation in individuals with obesity compared to individuals with normal-weight: findings from a representative German population sample
Authors: Weinberger Natascha-Alexandra , Luck-Sikorski Claudia 
Published: December 2020

Abstract
Purpose
Body image has been identified as an important factor in mental health in individuals with obesity. Previous studies have focused on negative body image and research of positive body image—particularly in obesity—is still in its infancy. The current study explored the positive body image facet body appreciation and the negative facet appearance evaluation in different BMI groups as well as men and women.

Methods
A total of 1003 participants of the general German public above the age of 18 years completed measures on body appreciation and appearance evaluation.

Results
Significantly lower body appreciation was observed in male participants with obesity compared to normal-weight participants. In women, the BMI groups did not differ significantly in body appreciation. BMI was negatively associated with appearance evaluation in both genders. While men and women did not differ in body appreciation, men reported lower appearance evaluation scores compared to women.

Conclusion
The present study is one of few that investigated positive body image in individuals with obesity compared to individuals with normal weight. The findings underscore the potential of body appreciation as a resource in treatment of body image concerns in individuals with obesity. Further implications for future research are discussed.

Level of evidence
III, case–control analytic study.
Development and Evaluation of Inexpensive Ultrasound Using A-Mode and M-Mode Signals to Identify Lung Depth and Avoid Risk of Pneumothorax in Acupuncture
Authors: Chen Ying-Ling , Hou Mark C. , Chang Shun-Chang , Chuang Kai-Wen , Lee Po-Yang , Huang Chih-Chung 
Published: December 2020

Abstract
Purpose
To increase patient safety, ultrasound detection acupuncture (UDA) has been developed, which can detect a safe depth for acupuncturists to avoid causing pneumothorax. This study aims to develop and evaluate a single-transducer ultrasound for acupuncture (UFA) to promote UDA.

Methods
Special A-mode and M-mode signals were analyzed to identify the depth of the lung. Six subjects were recruited to test the reliability and validity of UFA on GB21, LV14 and BL43 acupuncture points.

Results
The result showed UFA’s coefficient of variation was less than 0.2 and no difference in age, gender, and BMI of the subjects statistically, demonstrating excellent reliability. However, the content validity index of 0.51 did not meet expectations. UFA has good reliability, but it cannot reach the level of medical ultrasound. UFA uses A-mode and the seashore sign of M-mode to make a good identification of the lung, and it would be useful in the promotion of UDA.
Extracting Densely Covered Areas Within Floating Car Datasets Using Inductive Loop Detector Data
Authors: Röger Christian , Kalinic Maja , Krisp Jukka M. 
Published: December 2020

AbstractWe present an approach to use static traffic count data to find relatively representative areas within Floating Car Data (FCD) datasets. We perform a case study within the state of Nordrhein-Westfalen, Germany using enviroCar FCD and traffic count data obtained from Inductive Loop Detectors (ILD). Findings indicate that our approach combining FCD and traffic count data is capable of assessing suitable subsets within FCD datasets that contain a relatively high ratio of FCD records and ILD readings. We face challenges concerning the correct choice of traffic count data, counting individual FCD trajectories and defining a threshold by which an area can be considered as representative.
Revealing hidden drivers of macrofungal species richness by analyzing fungal guilds in temperate forests, West Hungary
Authors: Kutszegi Gergely , Siller Irén , Dima Bálint , Merényi Zsolt , Varga Torda , Takács Katalin , Turcsányi Gábor , Bidló András , Ódor Péter 
Published: December 2020

AbstractWe explored the most influential stand-scaled drivers of ectomycorrhizal, terricolous saprotrophic, and wood-inhabiting (main functional groups) macrofungal species richness in mixed forests by applying regression models. We tested 67 potential explanatory variables representing tree species composition, stand structure, soil and litter conditions, microclimate, landscape structure, and management history. Within the main functional groups, we formed and modeled guilds and used their drivers to more objectively interpret the drivers of the main functional groups. Terricolous saprotrophic fungi were supported by air humidity and litter mass. Ectomycorrhizal fungi were suppressed by high soil nitrogen content and high air temperature. Wood saprotrophs were enhanced by litter pH (deciduous habitats), deadwood cover, and beech proportion. Wood saprotrophic guilds were determined often by drivers with hidden effects on all wood saprotrophs: non-parasites: total deadwood cover; parasites: beech proportion; white rotters: litter pH; brown rotters: air temperature (negatively); endophytes: beech proportion; early ruderals: deciduous stands that were formerly meadows; combative invaders: deciduous tree taxa; heart rotters: coarse woody debris; late stage specialists: deciduous deadwood. Terricolous saprotrophic cord formers positively responded to litter mass. Studying the drivers of guilds simultaneously, beech was a keystone species to maintain fungal diversity in the region, and coniferous stands would be more diverse by introducing deciduous tree species. Guilds were determined by drivers different from each other underlining their different functional roles and segregated substrate preferences. Modeling guilds of fungal species with concordant response to the environment would be powerful to explore and understand the functioning of fungal communities.
Attitudes Toward Transgender People Among Medical Students in South Korea
Authors: Lee Sa Ra , Kim Min-A , Choi Mun Nyeong , Park Suyeon , Cho Jaehyun , Lee Chulmin , Lee Eun Sil 
Published: December 2020

Abstract

Introduction
Interventions aimed at changing knowledge, attitudes, and beliefs of resident physicians and medical students have been made to incite a significant positive increase in attitudes, comfort, and knowledge toward the lesbian, gay, bisexual, and transgender (LGBT) community, as well as increased levels of competency among participants.

Aim
To use insights from the attitudes of medical students toward transgender people and demonstrate that adding lectures on transgenderism would make the medical school curricula more comprehensive and trans-inclusive by improving overall attitudes toward the LGBT community.

Methods
A total of 49 medical students completed the preintervention survey with the Genderism and Transphobia Scale and Attitudes Toward Transgendered Individuals Scale, and then took a class on transgenderism, whereas 39 individuals completed the 4-week postintervention survey following the same measures.

Main Outcome Measure
Three items of survey were demographic characteristics, the Genderism and Transphobia Scale, and the Attitude Toward Transgender Individuals Scale.

Results
Although there was no significant difference in mean score between the preintervention and postintervention surveys, those who had minority individuals as peers and those who had previous LGBT-related education showed significantly positive attitudes than those without after the lecture. As a result of analyzing all the data from the pre/postintervention surveys, being of the female gender and having minority individuals as peers positively affected attitude.

Conclusion
Although there was no significant attitude change after the lecture, those who had previous LGBT-related education showed significantly positive attitudes at pre/postintervention surveys than those without. These findings suggest that raising awareness and education should be continued for a positive attitude toward more vulnerable groups such as the LGBT. Given the lack of studies on transgenderism that involve students in the medical profession in South Korea, this study shows the necessity of curricula creation of transgenderism education. This study aims to serve as a basis for curricula creation and student guidance that will help creating more positive attitudes toward sexual and gender minorities.
Tolerability and Optimal Therapeutic Dosage of Clomipramine for Premature Ejaculation: A Systematic Review and Meta-Analysis
Authors: Wu Po-Chien , Hung Chun-Shan , Kang Yi-No , Wu Chien-Chih 
Published: December 2020

Abstract

Introduction
Clomipramine is effective in treating premature ejaculation, a common form of male sexual dysfunction that affects individual's mental health and quality of life, but its optimal dosage remains controversial.

Aim
In this systematic review and meta-analysis, we aimed to evaluate the efficacy, safety, and optimal dose of clomipramine for treating premature ejaculation among men.

Methods
Eligible studies of PubMed, Embase, and Web of Science were identified from the date of inception to June 21, 2020. We conducted the study according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data of the study characteristics, intravaginal latency ejaculatory time (IELT), adverse events, success rate, and satisfaction rate of clomipramine vs placebo were extracted and analyzed. The risk ratio and mean difference were used for quantitatively analyzing binary outcomes and continuous outcomes. The standardized mean difference was applied to the outcome of satisfaction rate. The Mantel–Haenszel method was used for meta-analysis under random-effects model. To assess dose effect of clomipramine, a meta-regression analysis was performed.

Main Outcome Measures
The primary outcomes were the IELT and adverse events, and the secondary outcomes were the success rate and satisfaction rate of clomipramine treatment relative to the placebo.

Results
A total 14 randomized controlled trials with 710 patients were included for quantitative analysis. Clomipramine significantly increased the IELT compared with the placebo (mean difference: 1.47, 95% CI: 0.73–2.21). However, clomipramine was associated with higher risks of overall adverse events and adverse events in the nervous and respiratory systems. Significant dosage effects on the IELT (estimate: 0.0637, 95% CI: 0.0074–0.12) and a slightly increasing slope on adverse events were revealed.

Conclusion
Clomipramine increased the IELT and yielded greater satisfaction than the placebo, and the higher dose results in a superior IELT without leading to higher risk of adverse events under a dosage of 50-mg clomipramine.