bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 PANDEMIC AS A FORCE MAJEURE FOR MASSIVE LAYOFFS
Authors: Mustakim Mustakim , Syafrida Syafrida 
Published: May 2020

The fact of Corona Virus Disease 2019 (Covid-19) pandemics was often made as a reason by a lot of companies to conduct massive layoffs (PHK) in Indonesia. The regulation about force majeure to do massive layoffs (PHK) could only be found in Article 164 Act No. 13 Year 2003 about employment and it is not that specific about what kind of condition which could be categorized as force majeure that enables companies to conduct massive layoffs PHK. The statement of problem of this research is the spread of Covid-19 a condition categorized as force majeure that could become the reason to do a massive layoffs and how is the legal protection of worker toward the layoffs during the Covid-19 pandemics? This is normative research with constitutional and conceptual approach. The result from the observation and analysis indicated that the Covid-19 pandemics could be qualified as a force majeure but to conduct massive layoffs the companies need to experience loss or disadvantage and already closed permanently or massive layoffs is conducted for efficiency as what has been regulated by Article 164 point (1) and (3) Act No. 13 Year 2003 about employment by doing some steps in advance as stated in Minister Hand-outs No. SE-907/MEN/PHI-PPHI/X/2004, 28th October 2004 and the decision of the Supreme Court No. 19/PUU-IX/2011, 20th June 2012.
A Damping Modification Factor for Horizontal Acceleration Spectrum from Subduction Slab Earthquakes in Japan Accounting for Site Conditions
Authors: Zhao John X. , Jiang Mingxiu , Zhang Xiaonan , Kang Lili 
Published: May 2020

ABSTRACTWe present a damping modification factor (DMF) model for the total acceleration spectrum from subduction slab earthquakes. The model can be used for scaling a 5% damped design spectrum not associated with a particular earthquake that occurred in a subduction slab. The DMF model uses site-period-based site classes as the site-effect proxy. DMF models were constructed based on the spectrum for 13 damping ratios and 34 spectral periods; the DMF values can be calculated for any damping ratio between 1% and 30% and at any spectral period between 0.03 and 5.0 s. At moderately long and long spectral periods, the DMF values for acceleration spectrum are similar to or less than those for the displacement spectrum for a damping ratio of less than 5%, whereas the DMF values for the acceleration spectrum are similar to or larger than those for the displacement spectrum when the damping ratio is more than 5%. The standard deviations for acceleration and displacement spectra are similar at short or moderately short spectral periods, but those for the acceleration spectrum are about twice those for the displacement spectrum at long spectral periods. All standard deviations decrease linearly with increasing damping ratios in the logarithm scale when the damping ratio is less than 5% and increase linearly with increasing damping ratios in a logarithm scale for the other damping ratios. A set of simple functions for calculating various standard deviations is presented. The spectra from the Zhao, Jiang, et al. (2016) study for slab events scaled by the DMF values for other damping ratios vary smoothly with spectral period and have a trough at short spectral periods for a large event, a short distance, and high damping ratios. The relatively large between-event and within-site standard deviations are from the source and path effects.
Stress-Drop and Source Scaling of the 2019 Ridgecrest, California, Earthquake Sequence
Authors: Trugman Daniel T. 
Published: May 2020

ABSTRACTStress drop, while difficult to measure reliably and at scale, is a key source parameter for understanding the earthquake rupture process and its relationship to strong ground motion. Here, we use a P-wave spectral decomposition approach, designed for large and densely sampled datasets, to measure earthquake stress drop in the region surrounding the 2019 Ridgecrest, California, earthquake sequence. With more than 11,000 measurements of earthquake stress drop in the 20-yr time period from 2000 through 2019, this dataset provides an opportunity to understand how coseismic stress changes and how other geophysical factors relate to the distribution of stress drop and its evolution in space and time. We observe a mild but persistent deviation from self-similar scaling, with larger events having systematically higher stress drops, though this trend depends on the assumption of an omega-square source spectral model. Earthquake stress drop increases with hypocentral depth in this study region, and the Ridgecrest aftershocks tend to have higher stress drops than the pre-event seismicity. This is in part due to their deeper hypocenters. Coherent spatial patterns of stress drop in the aftershock sequence correlate with the slip distribution of the M 7.1 mainshock, whose northwest rupture tip terminated in a long-lived zone of enervated stress drop. Although physical interpretation of these results is complicated by the trade-offs between the timing, depth, and location of these earthquakes, the observations provide new insight into the physics of the earthquake source in an area of renewed seismic activity in southern California.
Clinical and radiological features of fahr’s disease: a mimicker of varied neurological manifestations
Authors: Mohapatra Suvendu Kumar , Nayak Rashmita Binod 
Published: May 2020

Fahr’s disease is a disorder characterized clinically by a wide spectrum of varied clinical-neurological and psychiatric manifestations occurring secondary to intracranial calcifications with subsequent neuronal cell loss. Though the disease can present in early childhood or adolescence the usual age of manifestation is around 4th-5th decades of life. We report a series of 6 Fahr’s disease cases with respect to different clinical and radiological manifestations. The details of different clinical manifestations with respect to the disease were studied. The frequency of symptoms, the radiological pattern of intracranial calcifications and the association of different parameters were studied. Progressive cognitive decline and Parkinsonism was detected in all the patients but in none of them it was the chief presenting feature. Seizure was presenting symptoms in 3 patients. Chorea was encountered in 2 patients as the presenting complaint. Mild wide-based cerebellar ataxic gait was found in only one patient but other cerebellar signs were absent. Athetosis, dyskinesia, or dystonia was present in none of our patient. CT scan revealed symmetric basal nuclei and cerebellar calcification in all patients. The disease needs a high index of suspicion and CT brain scanning should always be performed in patients younger than 50 years who present with refractory seizures, Parkinsonism and cognitive decline. However radiological findings did not predict the presentation and outcome.
Patients' and Nurses' Perceptions of What Constitutes Good Nursing Care: An Integrative Review
Authors: Lee Kyungmi , Kim Su Hyun 
Published: May 2020

BackgroundDifferences between patients' and nurses' perceptions of good nursing might be one of the barriers to optimal nursing care that matches the preferences of patients. A better understanding of the attributes of Good Nursing Care across different settings, circumstances, and patient populations will provide an integrated idea about Good Nursing Care, which can contribute to nursing theory development and future research.PurposeThis study aimed to integrate the literature on patients' and nurses' perceptions of what constitutes Good Nursing Care and thereby identify the similarities and differences in patients' and nurses' perceptions of Good Nursing Care.MethodsA literature search of PubMed, CINAHL, and MEDLINE was conducted for article published between January 2000 and June 2017. A total of 18 studies were identified and assessed using the Mixed Method Appraisal Tool. The studies were analyzed and synthesized using Swanson's theory of caring as the theoretical framework.ResultsSome dissents and agreements were found between patients and nurses regarding the crucial attributes of Good Nursing Care. While “enabling,” such as providing information, coaching, and guidance, was more emphasized by patients, “being with” (being present at the bedside) was more emphasized by nurses. “Doing for,” especially expert performance and enhancing physical comfort, was the most frequently mentioned attribute of Good Nursing Care by both patients and nurses.Implications for PracticeTheoretical developments regarding Good Nursing Care—characterized by a balance between sufficient nursing knowledge and competent technical skills on one hand and patient empowerment based on trusting relationships on the other hand—would promote the provision of Good Nursing Care in clinical practice.
Analisis Nilai Karakter Religius dan Nilai Karakter Tanggung Jawab Pada Tembang Dolanan Lir-ilir dan Sluku-Sluku Bathok
Authors: Dewi Tyass Puspita , Purwadi Purwadi , Mudzanatun Mudzanatun 
Published: May 2020

<p>Negara Indonesia adalah bangsa yang mempunyai berbagai macam seni budaya. Sekarang ini kita telah masuk dalam arus modernisasi yang membawa kemajuan dalam berbagai hal dan tak jarang pula membawa dampak negatif bagi identitas dan jati diri suatu bangsa jika kita tidak bisa menyikapinya dengan baik. Salah satu cara untuk memperbaiki penurunan kualitas karakter adalah dengan mengenalkan kembali budaya-budaya bangsa. Tembang dolanan anak Jawa merupakan salah satu sarana budaya yang mampu mengubah karakter generasi penerus bangsa Indonesia.</p><p>Tembang dolanan Jawa khususnya Lir-ilir dan Sluku-sluku Bathok memiliki makna, yang mengajarkan tentang pesan moral. Nilai karakter yang sering muncul dalam lirik lagu dapat dijadikan sarana bagi tenaga pendidik dan masyarakat dalam pembentukan kepribadian seseorang sesuai dengan nilai-nilai karakter yang ada di negara Indonesia.</p>
Constrained Liners Implanted Simultaneously at the Time of Acetabular Shell Revision with a Highly Porous Implant
Authors: Bedard Nicholas A. , Brown Timothy S. , Lewallen David G. , Trousdale Robert T. , Berry Daniel J. , Abdel Matthew P. 
Published: May 2020

Background:
Many surgeons are reluctant to use a constrained liner at the time of acetabular component revision because of concerns that doing so might result in early acetabular component loosening related to high bone-implant interface stresses transmitted from the constrained liner. We hypothesized that, with appropriate initial implant stabilization using highly porous acetabular components with robust supplemental screw fixation, constrained liners could be safely used at the time of acetabular revision.

Methods:
We retrospectively identified 148 revision total hip arthroplasties (THAs) in which a constrained liner of 1 design was cemented into a newly placed highly porous acetabular component fixed with supplemental screws (mean, 5 screws). The mean age at the time of revision THA was 69 years, and 68% of the patients were female. The most common indications for revision were 2-stage reimplantation (33%), recurrent dislocation (30%), and aseptic loosening of the acetabular component (22%) or both the acetabular and femoral components (9%). The mean duration of follow-up was 7 years.

Results:
There were no failures at the bone-implant interface. No cases of acetabular metal shell loosening were identified on radiographic analysis. The 10-year survival rates with acetabular revision and any reoperation as the end points were 75% and 67%, respectively. Overall, 33 hips (22%) required revision or reoperation because of infection or wound complications (n = 12), dislocation or mechanical failure of the constrained liner (n = 11), periprosthetic femoral fracture (n = 4), femoral loosening (n = 3), or other reasons (n = 3). The 10-year survival rate with re-revision for instability as the end point was 88% overall, which was similar to the 85% 10-year survival rate with re-revision for instability as the end point among hips that were specifically revised because of instability during index revision THA (p = 0.9).

Conclusions:
Implanting a constrained liner at the time of acetabular revision in high-risk patients resulted in no cases of aseptic metal acetabular component loosening in this large series. This finding is likely related to the fact that a highly porous acetabular component was utilized with robust supplemental screw fixation in each case. Such information is valuable as these data favor a paradigm shift when compared with some traditionally held tenets.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Volar Locked Plating Versus Closed Reduction and Casting for Acute, Displaced Distal Radial Fractures in the Elderly
Authors: Stephens Andrew R. , Presson Angela P. , McFarland Mary M. , Zhang Chong , Sirniö Kai , Mulders Marjolein A.M. , Schep Niels W.L. , Tyser Andrew R. , Kazmers Nikolas H. 
Published: May 2020

Background:
It remains unclear whether volar locked plating (VLP) yields a better functional outcome than closed reduction and casting (CRC) for elderly patients with an acute, displaced distal radial fracture. Our purpose was to conduct a systematic review and meta-analysis of randomized controlled trials comparing outcomes of VLP and CRC for elderly patients (age, ≥60 years).

Methods:
Multiple databases, including MEDLINE, were searched for randomized controlled trials evaluating outcomes following distal radial fracture treatment. Raw data were obtained for studies that included patients of all ages, and the elderly subgroup was included for analysis. The primary outcome was the Disabilities of the Arm, Shoulder and Hand (DASH) score at ≥1 year of follow-up. Secondary outcomes included the 3-month DASH score, range of motion, final radiographic alignment, and complications. Effect sizes for the comparison of each outcome between groups were pooled across studies using random-effects models with the inverse variance weighting method. Changes in DASH score were compared with a minimal clinically important difference (MCID) estimate of 10 to assess clinical relevance.

Results:
Of 2,152 screened articles, 6 were included. Demographics were similar for the 274 VLP and 287 CRC patients. DASH scores were significantly better following VLP than CRC at the time of final follow-up (12 to 24 months postoperatively; score difference, −5.9; 95% confidence interval [CI], −8.7 to −3.1) and at 3 months (−8.9; 95% CI, −13.0 to −4.8). VLP yielded significantly better palmar tilt, radial inclination, and supination, with no differences in ulnar variance, flexion-extension, pronation, or total complication rates.

Conclusions:
Functional outcome was significantly better following VLP than CRC 3 months into the treatment of acute, displaced distal radial fractures in an elderly population and up to 2 years after injury. However, the observed differences in the final DASH score did not exceed published estimates of the MCID, suggesting that clinical outcomes are similar for both treatment options.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Pediatric Tenosynovial Giant Cell Tumor of the Flexor Hallucis Longus Tendon Sheath
Authors: Williams Richard D. , Honeycutt M. Wesley , Manci Elizabeth A. , Nimityongskul Prasit 
Published: May 2020

Case:
An otherwise healthy 13-year-old girl presented with a firm nodule on the plantar right forefoot that was tender after cheerleading. Initial workup was unremarkable, but magnetic resonance imaging revealed a multilobulated mass surrounding the flexor hallucis longus tendon. Surgical resection revealed a tenosynovial mass without tendon infiltration. Pathologic examination was consistent with tenosynovial giant cell tumor. The patient resumed cheerleading and remained asymptomatic after 1 year.

Conclusion:
As far as we know, this is the first report of a tenosynovial giant cell tumor of the flexor hallucis longus in a pediatric patient; it illustrates the importance of considering this lesion when diagnosing a pediatric plantar mass.
Osteogenic activity of lactoferrin and its application in contemporary dentistry
Authors: Trybek Grzegorz , Misiakiewicz-Has Kamila , Preuss Olga , Szumilas Kamila , Szumilas Paweł , Aniko-Włodarczyk Magda , Grocholewicz Katarzyna 
Published: May 2020

AbstractIntroduction: Lactoferrin (Lf) is a protein in the transfer-rin family with many biological functions. One novel activity of lactoferrin described recently is its regulatory function in bone morphogenesis. Lactoferrin has been shown to promote the growth, development, and differentiation of osteoblasts as well as to decrease osteoclast survival. Lactoferrin receptors (LfRs) mediate the multiple functions of lactoferrin. This review focuses on LfRs associated with bone and the intestines. The best known LfR is small intestine LfR (intelectin), which facilitates iron absorption and iron metabolism in humans. Many data fromin vitroandin vivostudies have indicated that lactoferrin promotes bone formation by increasing the proliferation of osteoblasts and the ability of cells to synthesize and mineralize the bone matrix. Lactoferrin additionally inhibits osteoclastogenesis, reducing the number of osteoclasts and thus bone resorption. Lactoferrin, with its numerous antimicrobial, anti-inflammatory, and also osteogenic properties has found a number of applications in contemporary dentistry, especially in dental surgery, in periodontology, and in pedodontics.Summary: This review presents andin vivo in vitrostudies demonstrating the osteogenic and anti-inflammatory activity of Lf and its practical application in oral surgery and dentistry.
Navigating complexity through intuition and evidence-based guidelines: a mix-methods study among child and youth healthcare professionals
Authors: Erisman Jetske Charlotte , de Sabbata Kevin , Zuiderent-Jerak Teun , Syurina Elena V 
Published: May 2020

Abstract
Background: Dutch child and youth health care (CYHC) professionals monitor and assess the well-being of children. One of their main concerns is identifying cases of child abuse, which is an arduous and sensitive task. In these contexts, CYHC-professionals use both evidence-based guidelines aimed at increasing the quality of care through rationalised decision-making, and intuition. These two practices are seen as being at odds with each other, yet empirical research has shown that both are needed in healthcare. This study aims to unravel how intuition is perceived and used by Dutch CYHC-professionals when identifying and working with cases of child abuse, and how this relates to their evidence-based guidelines.Methods: A sequential exploratory mixed-methods design: in-depth semi-structured interviews with CYHC-practitioners focused on perceptions on intuition, which were followed by a survey amongst CYHC-professionals on the recognition and use of the concept.Results: The majority of CYHC-professionals recognise and use intuition in their daily work, stating that it is necessary in their profession. CYHC-professionals use intuition to: 1) sense that something is off, 2) differentiate between ‘normal’ and ‘abnormal’, 3) assess risks, 4) weigh secondary information and 5) communicate with parents. At the same time, they warn for its dangers as it may lead to ‘tunnel vision’ and false accusations. Conclusion: Intuition is experienced as an integral part of the work of CYHC-professionals. It is stated to be particularly useful in the case of child abuse, which is inherently complex as signs and evidence of abuse are hidden, subtle and unique in each case. CYHC- professionals use intuition to manage and navigate this complexity. There is an opportunity for guidelines to support reflection and intuition as a ‘good care’ practice.
Genome-wide identification and characterization of multiple C2 domains and transmembrane region proteins in Gossypium hirsutum
Authors: Hao Pengbo , Wang Hantao , Ma Liang , Wu Aimin , Chen Pengyun , Cheng Shuaishuai , Wei Hengling , Yu Shuxun 
Published: May 2020

Abstract
Background: Multiple C2 domains and transmembrane region proteins (MCTPs) may act as transport mediators of other regulators. Although increased number of MCTPs in higher plants implies their diverse and specific functions in plant growth and development, only a few plant MCTPs have been studied and no study on the MCTPs in cotton has been reported.Results: In this study, we identified 31 MCTPs in G. hirsutum, which were classified into five subfamilies according to the phylogenetic analysis. GhMCTPs from subfamily V exhibited isoelectric points (pIs) less than 7, whereas GhMCTPs from subfamily I, II, III and IV exhibited pIs more than 7.5, implying their distinct biological functions. In addition, GhMCTPs within subfamily III, IV and V exhibited more diverse physicochemical properties, domain architectures and expression patterns than GhMCTPs within subfamily I and II, suggesting that GhMCTPs within subfamily III, IV and V diverged to perform more diverse and specific functions. Analyses of conserved motifs and pIs indicated that the N-terminus was more divergent than the C-terminus and GhMCTPs’ functional divergence might be mainly contributed by the N-terminus. Furthermore, yeast two-hybrid assay indicated that the N-terminus was responsible to interact with target proteins. Phylogenetic analysis classified multiple N-terminal C2 domains into four subclades, suggesting that these C2 domains performed different molecular functions in mediating the transport of target proteins.Conclusions: Our systematic characterization of MCTPs in G. hirsutum will provide helpful information to further research GhMCTPs’ molecular roles in mediating other regulators’ transport to coordinate growth and development of various cotton tissues.
Synthesis and Antiproliferative Activity of Chlorinated Maprotiline Analogues&nbsp;
Authors: Sultan Mujeeb A. , Karama Usama , Almansour Abdulrahman I. , El-Taher Kamal Eldin , Elnakady Yasser A. , Mohaya Talal Abdulaziz , Galil Mansour S. A. 
Published: May 2020

Abstract
A novel chlorinated tetracyclic compound 13 of the class ethanoanthracene, as analogue of maprotiline, was prepared via multistep syntheses. The tetracyclic key intermediates 4 and 5 with its [2.2.2] system were built via a Diels-Alder reaction between acrolein and 1,8-dichloroanthracene.The synthesized chlorinated maprotiline analogues 6, 7 and 13 as well intermediates 4 and 5 exerted antiproliferative activity against cancer cell lines A549 and HepG2 at low micromolar concentrations. In addition, the intermediates 4 and 5 were also exerted high antiproliferative activity against HCT cell line. Interestingly, the intermediate 4 was the most active against all treated cell lines.