bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Perfect Storm: A Rheumatologist's Point of View on COVID-19 Infection
Authors: Kobak Senol 
Published: October 2020

:The new coronavirus infection (Covid-19) is a pandemic that has affected the whole world and progresses with high morbidity and mortality. It has a high contagion rate and a course capable of rapid lung involvement with severe acute respiratory distress syndrome (ARDS) and pulmonary insufficiency. A severe clinical picture develops as a result of a “perfect cytokine storm” which results from possible immunological mechanisms triggered by the viral infection. Immune system dysregulation and possible autoinflammatory and autoimmune mechanisms are responsible for a higher amount of cytokines release from immune cells. Although no clear treatment of Covid-19 infection has emerged yet, it is argued that some disease-modifying anti-rheumatic drugs (DMARDs) may be effective in addition to anti-viral treatments. These drugs (anti-malarial drugs, colchicum dispert, biologics) have been well known to rheumatologists for years because they are used in the treatment of many inflammatory rheumatologic diseases. Another important issue is whether DMARDs, which can cause severe immunosuppression, pose a risk for Covid-19 infection and whether they have been discontinued beforehand. Although there are insufficient data on this subject, considering the risk of disease reactivation, patients may continue their DMARDs treatment under the supervision of a rheumatologist. In this article, the possible immunological mechanisms in the pathogenesis of Covid-19 infection and the efficacy and safety of various DMARDs used in the treatment are discussed from a rheumatologist’s perspective in the light of recent literature data.
Withdrawal Notice: Recent Developments in Anti-Cancer Activity of Compounds Containing the Thioether Group
Authors: Han Muhammad İ. , Küçükgüzel Şükriye G. 
Published: October 2020

The article has been withdrawn by the Editorial office of the journal Anti-Cancer Agents in Medicinal
Chemistry; because of the lack of clarity and obscurity in the content regarding language.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

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Modeling and Study of Various Types of Inertial Mass Suspensions in the Sensitive Elements of Micromechanical Devices
Authors:   National Research University of Electronic Technology, Moscow, Russia, Aung Ye Ko Ko , Simonov B.M. ,   National Research University of Electronic Technology, Moscow, Russia, Timoshenkov S.P. ,   National Research University of Electronic Technology, Moscow, Russia
Published: October 2020

In microelectromechanical devices and systems (MEMS), capacitive micromechanical accelerometers (MMA) are used in airbag systems, machine vibration monitoring, navigation, seismology, microgravity measurements, etc. The most important structural elements of the sensing element are suspensions, through which the inertial mass is connected to a fixed frame. To ensure reliable operation and stability of sensor parameters, it is necessary to take into account the results of external factors already at the design stage of the sensor structure, especially its sensitive element, and at subsequent stages of the life cycle. In this work, the characteristic structures of suspension elements, which are made of silicon with different crystallographic orientations, are investigated and the results of modeling their most important parameters are presented. The simulation has been performed using the ANSYS program. The natural frequencies of inertial mass oscillations, residual mechanical stresses in the structural elements of silicon sensitive element with different crystallographic orientations have been calculated upon impact (up to 10 000 g). The natural vibration frequency changes and the dynamics of the change in the residual mechanical stress in the suspension elements with a temperature change in the range from +150 to –150 °C for a short time interval of 10 s, which corresponds to thermal shock, investigated. The results of studies of residual mechanical stresses arising upon impact and natural frequencies of inertial mass oscillations have been made it possible to develop recommendations on the choice of the design of suspension elements made of silicon, providing high sensitivity and stability of MMA parameters. It has been established that the use of folded springs with a rectangular or round cross-sectional shape with a suspension element thickness of 40 μm provides the highest temperature stability of the parameters. The results obtained are useful for developing real designs of MMA and other micromechanical devices
Model Pembelajaran Means-Ends Analysis dalam Menumbuhkembangkan Kemampuan Problem Solving dan Productive Disposition
Authors: Aras Andi 
Published: October 2020

Abstract:The problem solving and productive disposition ability of students is still low due to the inaccuracy of the learning model used by teachers in learning mathematics. This study aims to determine the effectiveness of the Means-Ends Analysis (MEA) learning model in developing students' problem solving and productive disposition abilities. This type of research is pre-experimental research with One-Group Pretest-Posttest Design. The data analyzed are the results of students' mathematical problem solving and productive disposition data of students after learning using the Means-Ends Analysis (MEA) learning model. From the results of this study, it can be seen that the Means-Ends Analysis (MEA) learning model is effective in developing students' problem solving and productive disposition abilities with the effectiveness criteria: (1) The results of students' problem-solving abilities are categorized to be effective both descriptively and inferentially in terms of posttest scores, normalized gain, and classical completeness. (2) The productive disposition of students is categorized effectively both descriptively and inferentially in terms of the score of productive disposition and increase in productive disposition. Abstrak:Rendahnya kemampuan problem solving dan productive disposition peserta didik disebabkan oleh ketidaktepatan model pembelajaran yang digunakan oleh guru dalam pembelajaran matematika. Penelitian ini bertujuan mengetahui keefektifan model pembelajaran Means-Ends Analysis (MEA) dalam menumbuhkembangkan kemampuan problem solving dan productive disposition peserta didik. Jenis penelitian yang digunakan adalah pre-experimental dengan desain One-Group Pretest-Posttest Design. Data yang dianalisis adalah hasil problem solving dan productive disposition peserta didik setelah pembelajaran matematika dengan menggunakan Means-Ends Analysis (MEA). Dari hasil penelitian ini diperoleh bahwa Means-Ends Analysis (MEA) efektif dalam menumbuhkembangkan kemampuan problem solving dan productive disposition peserta didik dengan kriteria keefektifan: (1) Hasil kemampuan problem solving peserta didik dikategorikan efektif baik secara deskriptif maupun secara inferensial yang ditinjau dari: skor posttest, gain ternormalisasi, dan ketuntasan klasikal. (2) Productive disposition peserta didik dikategorikan efektif baik secara deskriptif maupun secara inferensial yang ditinjau dari: skor productive disposition dan peningkatan productive disposition.
On Constraint Manifolds of Lorentz Sphere
Authors: Aktaş Buşra , Durmaz Olgun , Gündoğan Hal˙t 
Published: October 2020

Abstract
The expression of the structure equation of a mechanism is significant to present the last position of the mechanism. Moreover, in order to attain the constraint manifold of a chain, we need to constitute the structure equation. In this paper, we determine the structure equations and the constraint manifolds of a spherical open-chain in the Lorentz space. The structure equations of spherical open chain with reference to the causal character of the first link are obtained. Later, the constraint manifolds of the mechanism are determined by means of these equations. The geometric constructions corresponding to these manifolds are studied.
Iterative Solution of Weighted Linear Least Squares Problems
Authors: Carp Doina , Popa Constantin , Preclik Tobias , Rüde Ulrich 
Published: October 2020

Abstract
In this report we show that the iterated regularization scheme due to Riley and Golub, sometimes also called the iterated Tikhonov regularization, can be generalized to damped least squares problems where the weights matrix D is not necessarily the identity but a general symmetric and positive definite matrix. We show that the iterative scheme approaches the same point as the unique solutions of the regularized problem, when the regularization parameter goes to 0. Furthermore this point can be characterized as the solution of a weighted minimum Euclidean norm problem. Finally several numerical experiments were performed in the field of rigid multibody dynamics supporting the theoretical claims.
On a free boundary value problem for the anisotropic N-Laplace operator on an N−dimensional ring domain
Authors: Nicolescu A. E. , Vlase S. 
Published: October 2020

Abstract
In this paper we are going to investigate a free boundary value problem for the anisotropic N-Laplace operator on a ring domain

Ω
:
=

Ω

0

\

Ω
¯

1

⊂

𝕉

N

\Omega : = {\Omega _0}\backslash {\bar \Omega _1} \subset {\mathbb{R}^N}

, N ≥ 2. Our aim is to show that if the problem admits a solution in a suitable weak sense, then the underlying domain Ω is a Wulff shaped ring. The proof makes use of a maximum principle for an appropriate P-function, in the sense of L.E. Payne and some geometric arguments involving the anisotropic mean curvature of the free boundary.
Successful Repair of Coarctation of the Aorta and Obstructive Total Anomalous Pulmonary Veins Connection in a One-Day-Old Newborn
Authors: Teplov P.V. , Miller A.Yu. , Titov A.M. , Sakovich V.A. 
Published: October 2020

Abstract
A clinical case of successful repair of a combination of total anomalous pulmonary venous connection (TAPVC) with collector stenosis in one-day-old newborn. Only one case of successful correction of such a pathology is reported previously. The operation was performed with cardiopulmonary bypass and temporary antegrade brain perfusion. The narrowed aortic area was resected, the integrity of the aortic arch was restored using an extended anastomosis, and TAPVC correction was performed using a “sutureless technique”. The postoperative period was uneventful. The newborn was discharged from hospital on the 12th day.
Changes in Coagulation Parameters After Permanent Pacemaker Implantation
Authors: Yoncheva I.D. , Biserov D.E. , Negreva M.N. 
Published: October 2020

Abstract
The connection between venous thrombotic events in patients with implanted pacemakers and changes in coagulation factors has been the basis of numerous scientific studies for years. Results show that the effect on the coagulation system is a long-term and dynamic process, as well as presence of a significant dependence with many concomitant cardiovascular diseases.
Advances in medicine in recent decades and increase in life expectancy of patients with implanted cardiac devices (ICD) increase the risk of a variety of complications. These adverse events may be associated with development of thrombosis, change in the stimulation threshold, need for ablation due to concomitant rhythm pathology and others. Analysis of data from literature shows unequivocally that placement of endocardial electrodes leads to activation of the coagulation system in the body. On the one hand, this is a result of the direct traumatic moment and endothelial damage in the early post-procedure period, and subsequently, the presence of electrodes of the foreign body type in some individuals can provoke a procoagulation state.
More in-depth research is needed in this area to clarify the answers to these questions, namely: in which phase of the coagulation cascade are the changes most significant; is there a way to anticipate these changes and prevent them accordingly; is disturbed homeostasis of coagulation temporary or persistent.
These questions will be answered after sufficient data have been accumulated on these changes and how to modulate them.
A comparative analysis of urban development and the tram line network in Lviv in 1932−2016
Authors: Cegiełko Szczepan , Karsznia Izabela 
Published: October 2020

Abstract
This article presents a comprehensive analysis of changes in urban development (including certain types of public buildings) and changes in the routes of Lviv’s tram lines over the last 80 years, related to the territorial and demographic development of the city. For this purpose, maps comparing these elements of urban infrastructure between 1932 and 2016 were developed. The analysis was carried out based on a plan of Lviv from 1932, contemporary vector data taken from OpenStreetMap, ArcGIS basemaps, Google Street View panoramic images, information contained in interwar Lviv guides, and supplementary information from other sources.
Disseminated Superficial Actinic Porokeratosis in the Elderly: A Case Report
Authors: Nišavić Miloš , Jovanović Marina , Golušin Zoran , Vučković Nada , Vujanović Ljuba , Roš Tatjana 
Published: October 2020

Abstract
Currently, most authors believe that disseminated superficial actinic porokeratosis (DSAP) is an inherited or acquired dermatologic disorder of keratinization that occurs in genetically predisposed individuals after adequate exposure to ultraviolet (UV) rays, or immunosuppression. Lesions in DSAP start in sun-exposed areas most commonly in the third or fourth decade of life. The lesions are pink to brownish papules and plaques with a raised scaling ridge, histologically seen as a column of parakeratotic keratinocytes, the cornoid lamella. DSAP is not only the most common, but also the most often overlooked form of porokeratosis (P). Here we present a 77-year-old male with DSAP, who sporadically developed initial skin lesions at the age of 67, at the time when his personal and medical history were significantly long for chronic intensive sun exposure and type 1 insulin dependent diabetes mellitus. We established the diagnosis of DSAP based on personal and medical history, clinical presentation, auxiliary methods such as dermoscopy, and confirmed with pathohistological findings. We advised the patient to avoid sun exposure and to apply photo-protective sunscreens, emollients and keratolytics. After five years of monitoring his changes, we continue to control his lesions for any possible alteration. Although mutations in several genes and data on sun exposure may be responsible for the onset of the disease, most cases of DSPA occur sporadically and without involving the facial skin, as in our case. Lesions usually begin in the third or fourth decade of life. In the elderly, an additional trigger may be present, such as e.g. age-related decreased immune competence. Diabetes mellitus may also be associated with immunodeficiency in the elderly. Recently, DSPA has been a special subtype of DSPA in the elderly. Malignant alteration can occur in DSPA, most commonly in lesions that are long lasting, large, in the elderly, or in lesions in immunocompromised individuals. In conclusion, this is the case of a 77-year-old male person, who sporadically developed the so-called subtype DSPA in the elderly. In addition to UV radiation, the relevant suggestive trigger factors were the immunosuppressive effects of diabetes mellitus and chronological aging.
A Rare Case of Acute Generalized Exanthematous Pustulosis with Drug-Induced Liver Injury caused by Pyrazinamide
Authors: Nurul St. , Wahyuni Reski , Djawad Khairuddin , Ilyas Faridha S , Dewiyanti Wiwiek , Rahma St Nur , Herlina Irma 
Published: October 2020

Abstract
Acute Generalized Exanthemataous Pustulosis (AGEP) is a rare acute pustular eruption that is mostly induced by drugs. Aside from cutaneous eruptions, systemic symptoms such as leukocytosis, neutrophilia, and internal organ involvement such as liver, kidney, respiratory system, and bone marrow, may occur, although uncommon. Liver involvement usually results in a two- or three-fold increase of liver enzymes and rarely exceeds that. Pyrazinamide is the first-line anti-tuberculosis drug that is potentially hepatotoxic, but rarely shows dermatologic manifestations. We report a rare case of AGEP with drug induced liver injury due to pyrazinamide in a young patient with tuberculosis.
‘To look until your head starts spinning’
Authors: Franaszek Andrzej 
Published: October 2020

Abstract
The article describes what kind of meaning the Polish poet Zbigniew Herbert drew from his many encounters with the Netherlands, its 17th-century painting, its history and a specific form of social norms. It provides the reader with a closer look at the subjective vision of Dutch culture presented by Herbert in the volume of essays, Still Life with a Bridle. It indicates that the poet has constructed a kind of utopia here, describing, among other things, the role of the artist and his commitment to society, and it confronts the poet’s vision with the opinions of contemporary art historians. Finally, it discusses two of Herbert’s unfulfilled intentions: books devoted to the works of Vermeer and Rembrandt, as well as reconstructing the chronology of Herbert’s subsequent journeys to the Netherlands: from 1967 to 1994.
Prediction of an Optimum Total Resistance Coefficient on Catamaran using Design of Experiment (DOE) Incorporated with CFD Approach
Authors: Fitriadhy Ahmad , Lim Sun Yin , Maimun Adi 
Published: October 2020

In presence of complex hydrodynamic interferences between two demihulls on a catamaran ship has been prone to have a reliable prediction to her optimum total resistance. To achieve this, the author presents a Computational Fluid Dynamic (CFD) modelling incorporated with Design of Experiment (DOE) approach. Several parameters such as effect of Froude number ( ) with respect to various lateral separation ratios (S/L) of the catamaran have been taken into account. Here, the optimum total resistance coefficient (CT) has been mainly set within the range of S/L ratio 0.2 ≤ S/L ≤ 0.4 associated with Froude number 0.56 ≤ ≤ 0.66. The primary objective function of this optimization model has led towards minimizing a drag force and increased a lift force with respect to the above S/L ratios. In general, the simulation results had seemed quantitative similarity values for the optimum of 0.6589, 0.6599 and 0.6596 with S/L ratios of 0.2, 0.3 and 0.4, respectively. In the case of = 0.56, the optimum S/L ratios of 0.2993 and 0.3988 have resulted in insignificant reduction of CT by 0.62% and 0.32% as compared to S/L of 0.3 and 0.4, respectively. Similarly, the optimum S/L ratios of 0.2750 and 0.3750 with = 0.66 have led to reduce by 0.14% and 0.46% as compared to S/L of 0.3 and 0.4, respectively. This CFD simulation results are very useful as preliminary data for the optimised ship resistance, which is mainly required to predict a ship powering in the early design stage.
Analisis Produktivitas Bongkar Muat pada Pelabuhan Soekarno
Authors: Yusuf Yusrifah Indahsari , Idrus Misliah , Chairunnisa Andi 
Published: October 2020

Abstrak
Jumlah arus bongkar muat di pelabuhan Makassar mengalami kecenderungan peningkatan volume setiap tahunnya. Dari data arus bongkar muat barang di pelabuhan Soekarno (2007 – 2015) berkembang secara fluktuatif (tidak Stabil) dari tahun 2011 hingga 2013 terjadi peningkatan pesat hingga mencapai 1.631.895 namun tidak di dukung oleh fasilitas bongkar muat sehingga kemacetan truk di sekitar dermaga baik dalam maupun luar dermaga. Penelitian ini bertujuan menentukan produktivitas dan kebutuhan alat bongkar muat dimasa yang akan datang dengan menggunakan metode efektivtas dan time series. Analisis kenaikan/penurunan poduktivitas bongkar dalam tiga tahun terakhir pada pelabuhan Soekarno dengan data ditahun 2017 sebesar 30287,46 ton, 2018 mengalami kenaikan barang yang dibongkar sebesar 61662,59 ton dan 2020 barang yang dibongkar mengalami penurunan sebesar 45686,57 ton. Dari data di atas dapat dilihat bahwa produktivitas bongkar di pelabuhan Soekrano tahun 2017, 2018, 2020 beruturut-turut yaitu sebesar 4,509 TGJ, 15,241 TGJ, 14,642 TGJ. Sedangkan produktivitas muat pada tiga tahun terakhir sebesar 32603 ton ditahun 2017, 2018 terjadi peningkatan muatan sebesar 61485,4 ton dan 2020 jumlah muatan sebesar 87133,6 ton. Dari data diatas dapat dilihat bahwa produktivitas muat di Pelabuhan Soekarno tahun 2017, 2018, 2020 berturut-turut adalah 32,860 TGJ, 61,980 TGJ, 84,560 TGJ. Metode peramalan untuk Arus barang dari tahun 2020 – 2035 (Jangka pendek, jangka menengah dan jangka Panjang), dari hasil peramalan arus barang didapatkan pada tahun 2025 arus barang di pelabuhan Soekarno sebesar 404368 Ton, tahun 2030 sebesar 657098 Ton, dan tahun 2035 sebesar 909828 Ton . Berdasarkan hasil peramalan jumlah arus barang yang dibongkar dan dimuat di Pelabuhan Soekarno, mengalami kenaikan setiap tahunnya. Kebutuhan bongkar muat di pelabuhan Soekarno menunjukkan bahwa 1 Unit Crane Kapasitas 25 Ton masih mencukupi untuk melayani barang umum sampai pada Tahun 2035, dengan arus barang sebesar 758190 Ton, Akan tetapi pada tahun 2033,2034,2035 kapasitas bongkar muat sudah tidak mencukupi yaitu lebih besar dari 804000 Ton. Oleh karena itu disarankan untuk melakukan penambahan alat bongkar muat pada tahun 2035.
COVID-19 recovery rate and its association with development
Authors: Singh Akancha , Chattopadhyay Aparajita 
Published: October 2020

Objectives:
The recovery rate is important to determine a country’s development towards controlling coronavirus. It is a function of myriad factors – death rate, cases requiring hospitalization, quality of care, and discharge policies, among others. India’s recovery rate is growing steadily from an earlier low of 10% to 11%. It is imperative to understand the determinants of recovery rate in a country to enable improvements in the same.

Material and Methods:
COVID-19 data have been compiled from several sources, including the Ministry of Health and Family Welfare, National Disaster Management Authority, and Indian Council of Medical Research and demographic and health data from Census of India, 2011, National Health Profile, 2019, and were used. The study uses linear regression to understand the relationship between recovery rate and development indicators in India.

Results:
Our analysis emphasizes the beneficial impacts of the health system and better economy on the recovery rate. Investment in health, urban stay, non-slum and non-poor population, and effective governance is instrumental in improving recovery rate.

Conclusion:
Scaling up health facilities and medical infrastructure, slum decongestion, focus on economically weaker sections, capacity building of health workers and ameliorating long-term investments in health, health research, and better quality of living are also essential to address recovery of COVID-19.