bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regulating Charge Separation Via Periodic Array Nanostructures for Plasmon‐Enhanced Water Oxidation
Authors: Gao Yuying , Zhu Qianhong , Zhao Jianfeng , Xie Yuxin , Fan Fengtao , Li Can 
Published: December 2024

AbstractPlasmonic resonance intensity in metallic nanostructures plays a crucial role in charge generation and separation, directly affecting plasmon‐induced photocatalytic activity. Engineering strategies to enhance plasmonic effects involve designing specific nanostructures, such as triangular nanoplates with sharp corners or dimer nanostructures with hot spots. However, these approaches often lead to a trade‐off between enhanced plasmonic intensity and resonance energy, which ultimately determines local charge density and photocatalytic performance. Here, inspired by theoretical predications, it is shown that a flexibly controlled plasmonic photocatalyst, consisting of an ordered array of Au nanoparticles on a SrTiO3 surface, exhibits an enhanced surface plasmon resonance (SPR) intensity while maintaining a constant SPR resonant energy, due to the presence of surface lattice resonance. This trade‐off results in improved charge separation efficiency and an increase in local charge density at catalytically active sites, as verified by theoretical simulations, surface photovoltage microscopy, and ultrafast transient absorption spectroscopy. Moreover, the optimized periodic photocatalyst shows a 7‐fold increase in water oxidation activity over disordered nanostructures. This work provides a novel approach for balancing the intensity and energy of SPR, which will contribute to optimizing photocatalytic activity on plasmonic platforms.
Substrate‐Free Inorganic‐Based Films for Thermoelectric Applications
Authors: Liang Zhongxin , Shu Rui , Xu Congcong , Wang Yu , Shang Hongjing , Mao Jun , Ren Zhifeng 
Published: December 2024

AbstractThe development of highly integrated electronic components and the Internet of Things demands efficient thermal management and uninterrupted energy harvesting, which provides exciting opportunities for thermoelectric (TE) technology since it allows direct conversion between electricity and thermal energy. The improved output performance of TE devices has traditionally been driven by advancements in inorganic materials. Recently, there has been growing interest in studying substrate‐free inorganic‐based TE thin films because they provide improved adherence to curved surfaces and offer a more compact size compared to the corresponding rigid form of these materials. This review begins by summarizing various methods for fabricating freestanding inorganic‐based TE films, including leveraging the intrinsic plasticity of certain materials, exfoliating layered‐structure materials, using sacrificial substrates, and creating composites with flexible components such as polymers and carbon‐based materials. A key challenge in achieving high device performance is determining how to maintain the favorable TE properties of inorganic materials. This can be addressed through strategies such as high inorganic content loading, multicomponent engineering, and interfacial structure design. The review also discusses the applications of substrate‐free inorganic‐based TE devices in both power generation and solid‐state cooling. Finally, it outlines current challenges and proposes potential research directions to further advance the field.
Amylopectin‐based Hydrogel Probes for Brain‐machine Interfaces
Authors: Qin Yanxia , Zhao Hao , Chang Qi , Liu Yan , Jing Zhen , Yu Dehai , Mugo Samuel M. , Wang Hongda , Zhang Qiang 
Published: December 2024

AbstractImplantable neural probes hold promise for acquiring brain data, modulating neural circuits, and treating various brain disorders. However, traditional implantable probes face significant challenges in practical applications, such as balancing sensitivity with biocompatibility and the difficulties of in situ neural information monitoring and neuromodulation. To address these challenges, this study developed an implantable hydrogel probe capable of recording neural signals, modulating neural circuits, and treating stroke. Amylopectin is integrated into the hydrogels, which can induce reorientation of the poly(3,4‐ethylenedioxythiophene) (PEDOT) chain and create compliant interfaces with brain tissues, enhancing both sensitivity and biocompatibility. The hydrogel probe shows the capability of continuously recording deep brain signals for 8 weeks. The hydrogel probe is effectively utilized to study deep brain signals associated with various physiological activities. Neuromodulation and neural signal monitoring are performed directly in the primary motor cortex of rats, enabling control over their limb behaviors through evoked signals. When applied to the primary motor cortex of stroke‐affected rats, neuromodulation significantly reduced the brain infarct area, promoted synaptic reorganization, and restored motor functions and balance. This research represents a significant scientific breakthrough in the design of neural probes for brain monitoring, neural circuit modulation, and the development of brain disease therapies.
Implantable Ultrasound‐Powered MXene/PVA Hydrogel‐Based Generator for Treatment of Glioblastoma
Authors: Hu Xiaoping , Qiu Ziyi , Yang Yilin , Xu Ting , Sheng Kai , Lu Weicheng , Xie Jingdun , Xu Bingzhe 
Published: December 2024

AbstractGlioblastoma (GBM) is a lethal disease with a poor prognosis due to its strong infiltration, which makes it difficult to remove completely. In this study, an implantable, modulus‐tunable, and ultrasound‐powered MXene/PVA hydrogel‐based tumor treatment device (UP‐MPH‐TTD), which generates specific electromagnetic alternating fields that disrupt the mitosis of cancer cells without adversely affecting normal neurons is developed. The MXene/PVA hydrogel is used to form a tumor treatment field due to its high biocompatibility, excellent flexibility, and high conductivity, which improves ultrasonic electrical conversion efficiency and significantly reduces the size of the equipment. The implantable UP‐MPH‐TTD is wirelessly ultrasound‐powered, small‐sized, lightweight, and simply structured, significantly boosting therapeutic efficiency and reducing restrictions on patient movement. In vitro and in vivo experiments confirmed the device's therapeutic effect, demonstrating a ≈92% inhibition rate in the growth of clinical tumor cells and a 73% reduction in tumor area in tumor‐bearing mice. The promising results indicate the broad application potential of the device in the treatment and prognostic improvement of GBM.
Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity‐Switching, Self‐Immobilizing, Near‐Infrared Fluorogenic β‐Lactamase Probe Enriched within Bacteria
Authors: Chen Fangfang , Li Yuyao , Peng Yan , Zhu Yifan , He Gao , Zhang Zhengwei , Xie Hexin 
Published: December 2024

AbstractThe emergence of antibiotic resistance, particularly bacterial resistance to β‐lactam antibiotics, the most widely prescribed therapeutic agents for infectious diseases, poses a significant threat to public health worldwide. The discovery of effective therapies against antibiotic‐resistant pathogens has become an urgent need, necessitating innovative approaches to accelerate the identification and development of novel antibacterial agents. On the other hand, the expression of the β‐lactam‐hydrolyzing enzyme (β‐lactamase), the major cause of bacterial resistance to β‐lactam antibiotics, provides a distinctive opportunity to visualize bacterial infection, evaluate the efficacy of existing antibiotics, screen for novel antibacterial agents, and optimize drug dosing regimens in live animals. Herein, a hydrophilicity‐switching, self‐immobilizing, near‐Infrared fluorogenic β‐lactamase probe for the highly sensitive imaging of bacterial infection in live mice is reported. This probe, in addition to a significant increase in fluorescence upon selective hydrolysis by β‐lactamases as conventional β‐lactamase probes, also massively enriches within β‐lactamase‐expressing bacteria (over 1500‐folds compared to the incubation medium), which renders excellent sensitivity in the imaging of bacterial infections in living animals. This agent has proven to enable the assessment of antibiotic therapeutic efficacy and potency of β‐lactamase inhibitors in living animals in a non‐invasive and much more convenient manner.
Polyester Upcycling to Glycine via Tandem Thermochemical–Electrochemical Catalysis
Authors: Ma Yingxin , Chen Wenxuan , Yuan Wenfang , Chen Zhuan , Du Mengmeng , Cai Lejuan , Wang Wenlong , Xing Mingyang , Qiu Bocheng 
Published: December 2024

AbstractDeconstruction of polyethylene terephthalate (PET) plastics into commodity chemicals such as glycine presents a promising route for waste valorization. However, directly upcycling PET into glycine via thermocatalysis typically requires harsh conditions (e.g., high H2 pressure and elevated temperature) while suffering from limited selectivity and high carbon footprint. Herein, a cascade thermochemical–electrochemical catalysis is developed to exploit glycine from end‐of‐life PET plastics with high selectivity and yield, without the use of hydrogen gas in the entire process. PET is first degraded into oxalic acid via thermochemical oxidative depolymerization using an active and robust HY‐zeolite‐supported Au catalyst under a low O2 pressure (0.3 MPa), and then valorize oxalic acid intermediate into glycine via a two‐step electroreduction over an earth‐abundant TiO2 catalyst. The proposed cascade catalysis approach is resilient to impurities from realistic PET waste streams, and enables a continuous conversion of various PET goods into glycine with an overall yield of 75%. Techno‐economic analysis and life cycle assessment demonstrate that the cascade approach is a cost‐effective and low‐carbon route for PET upcycling. This hybrid thermochemical–electrochemical technology paves a way to leverage cascade catalysis for mitigating plastic pollution while producing high‐value chemicals.
SAHA inhibits lung fibroblast activation by increasing p66Shc expression epigenetically
Authors: Dong Yiheng , Peng Jieting , Zhang Xiangyu , Wang Qiong , Lyu Xing 
Published: December 2024

AbstractObjectivesTo investigate the effects of suberoylanilide hydroxamic acid (SAHA) on lung fibroblast activation and to examine the role of p66Shc in this process.MethodsAn in vitro pulmonary fibrosis model was established using transforming growth factor‐β (TGF‐β)‐induced MRC‐5 lung fibroblasts. The proliferation and migration capacities of MRC‐5 cells, along with the expression of fibrosis‐related genes, were assessed following treatment with SAHA and/or silence of p66Shc.ResultsIn TGF‐β‐induced MRC‐5 lung fibroblasts, SAHA treatment significantly inhibited cell proliferation and migration, as well as the expression of fibrosis‐related genes, including collagen I and α‐smooth muscle actin (SMA). Western blot and immunofluorescence assays revealed that SAHA increased p66Shc expression in both whole cells and mitochondria. Additionally, mito‐SOX assay confirmed that SAHA treatment led to a marked accumulation of mitochondrial reactive oxygen species (ROS). However, silencing of p66Shc significantly reversed the aforementioned effects of SAHA on MRC‐5 cells. Furthermore, chromatin immunoprecipitation (ChIP) assays demonstrated that SAHA enhanced active histone markers, H3K9Ac and H3K4Me3, in the p66Shc gene region.ConclusionsSAHA alleviates lung fibroblast activation and migration by increasing p66Shc expression and mitochondrial ROS generation through epigenetic modifications of histone 3.
Relationships Between Mechanical Behavior and Structure/Properties for Macroscopically Homogeneous Porous Composites Containing Randomly Shaped Filler
Authors: Černý Miroslav , Menčík Přemysl 
Published: December 2024

ABSTRACTThe work focuses on researching relationships between structure/properties and mechanical behavior of porous composites. The primary data comes from tensile testing. The observed properties include elastic modulus, ultimate strength, ultimate strain, and energy need for ultimate strength achievement. The studied materials include composites based on different polyurethane matrices and one rubber filler with various filler and porosity contents. Presented work expands the possibilities of an approach based on measured data fitting by a suitable function followed by obtained parameters interpolation. The utilization of new structural parameters leads to a spatial linear function shape instead of spatial exponential. The newly introduced equation is z

c
= z

m
+ z

m
· (b · p
1 + c · p
2), where z

c
/z

m
is generally labeled mechanical property value for composite/nonporous matrix, p
1/p
2 are suitable structural parameters, and b/c are fitting parameters subjected to interpolations by logarithmic function containing values of properties typical for matrices. The work focuses on studying the case of different matrices and one kind of filler. The work includes all potentially valuable interpolations for earlier mentioned properties with the most interesting results in cases of pairs p
1/p
2 containing two from three parameters: n (porosity), 1 − v

m
(v

f
+ porosity), and v

f
(filler volume fraction).
Noncovalent Cross‐Linked Network‐Reinforced High‐Toughness Polyvinyl Alcohol/Hyperbranched Polyester Films Obtained Through Solution Blending
Authors: Wang Yaomin , Zou Kaijuan , Wang Jun , Kang Jun , Yu Wenxia , Tian Huafeng , Ouyang Yuge , Jin Yujuan , Kumar Rajesh , Luo Xiaogang 
Published: December 2024

ABSTRACTPolyvinyl alcohol (PVA) exhibits good water solubility, biocompatibility, and gas barrier properties. It is an important renewable and biodegradable polymeric material and is widely used in drug delivery, food packaging, tissue engineering, etc. However, its application is limited by insufficient mechanical performance. Hyperbranched polymers are a class of highly branched, structured macromolecular polymers with multiple branching sites and rich end functional groups. In this work, blend films were prepared by mixing PVA with water‐soluble hyperbranched polyester (HBPE) using the solution casting method. The results showed that the hydroxyl groups of HBPE could form a hydrogen‐bond‐based cross‐linking network with the hydroxyl groups of PVA. This, in turn, will effectively improve the mechanical properties, water absorption, thermal stability, etc. of the blend film. When the mass ratio of HBPE to PVA is 1:4, the elongation at break of the blend film was 404.23% with a tensile strength of 39.97 MPa. The prepared PVA/HBPE blend material is expected to be more widely applied in fields such as tissue engineering, packaging materials, etc.
Effects of 6FAP on the Electrical Properties of Al2O3/Epoxy Resin Composites
Authors: Zheng Huan , Zhang Jinyu , Jiao Shuqing , Han Yongsen , Wang Xinyu , Li Zhonghua 
Published: December 2024

ABSTRACTThe fluorination of Al2O3/epoxy composites is achieved through the grafting of 2,2‐bis(3‐amino‐4‐hydroxyphenyl) hexafluoro propane (6FAP) onto the epoxy molecule via ring‐opening reactions. The microstructures, Fourier infrared spectra, and water contact angle of the untreated and fluorinated Al2O3/epoxy composites are characterized. The composites' dielectric properties and DC conductivity, DC breakdown, surface flashover, and surface potential decay are also measured. The results demonstrate that 6FAP has been successfully grafted onto the epoxy molecules, and Al2O3 particles are uniformly distributed in the composite. The hydrophilicity of the fluorinated Al2O3/epoxy composite is enhanced. The fluorinated Al2O3/epoxy composite exhibits more favorable electrical properties than the untreated composite. The breakdown strength and surface flashover voltage of the fluorinated Al2O3/epoxy composite increased by 12.98% and 11.10%, respectively. Compared to the untreated composite, the deep trap density of the fluorinated Al2O3/epoxy composite increases, which contributes to the reduction in carrier mobility and to the enhancement of breakdown strength and surface flashover voltage. This work suggests that fluorination via 6FAP has potential applications in the improvement of electrically insulating materials.
Glucopyranosylamine‐Derived Dinuclear Mo(VI) Complex: An Efficient Catalyst for the Oxidation of Thiols into Uronium Aryl/Alkyl Sulfonates
Authors: Parikh Anuvasita , Parikh Parmeshthi , Kumar Madduluri Vimal , Sah Ajay K. 
Published: December 2024

AbstractA combination of dinuclear molybdenum complex of bis‐(4,6‐O‐ethylidene‐β‐D‐glucopyranosylamine)‐1,4‐dihydroxy‐2,5‐dibenzylidene with urea hydrogen peroxide (UHP) has been used as an efficient catalyst for the selective oxidation of thiols into corresponding uronium sulfonate salts (Ur+R/ArSO₃−). The reaction was carried out in ethanol at room temperature using sixteen different aliphatic and aromatic thiols, which afforded an excellent isolated yield of products (89–98 %). We have established the evolution of hydrogen gas during the oxidation process by gas chromatography, however no such reports are available for similar reactions in the past. The products have been characterized by several analytical techniques like FTIR, NMR, HRMS, etc., and the molecular structure of two compounds has been established by single crystal X‐ray diffraction studies. The mechanistic insights of the catalytic process have also been explored, and during this process, the formation of disulfides, sulfinothioates, and sulfinic acids has been noticed. Two representative reactions have also been reported where (i) uronium p‐chlorobenzene sulfonate has been converted to corresponding sulfonic acid and (ii) diphenyl diselenide has been oxidized to corresponding selenonate salt.
Polybenzimidazole Based Porous Organic Polymers with Dipyridine Units for Iodine Capture
Authors: Du Ziwei , Wang Zhixuan , Wang Ruoting , Liu Chao 
Published: December 2024

AbstractClean energy nuclear power generation is always accompanied by the release of harmful radioactive iodine. Therefore, developing efficient adsorbents has become a universal strategy to deal with this problem. Two distinct porous organic polymers (BTM‐POP and DAB‐POP) containing dipyridine units and benzimidazole structure were synthesized by 5,5′‐([2,2′‐bipyridine]‐5,5′‐diyl) diisophthalaldehyde with 1,2,4,5‐benzenetetramine (BTM) or 3,3′‐diaminobenzidine (DAB), respectively. The structures and morphologies of BTM‐POP and DAB‐POP were confirmed through Fourier transform infrared (FT‐IR) spectroscopy, N2 sorption isotherm measurement and scanning electron microscopy (SEM). Furthermore, iodine vapor capture of BTM‐POP and DAB‐POP reach 3.26 g g−1 and 3.58 g g−1, respectively. Mechanism study reveals that the adsorbed iodine in the material mainly exists in the form of I3− and I5− and the adsorption sites are mainly bipyridine and benzimidazole units. The results show that two POPs exhibit good thermal/chemical stability, high pore properties, and offer more adsorption sites. In combination with rich N atom content, large conjugated structure, synergistically influences the iodine vapor capture capacity of POPs.
Exploring the Multifaceted Health Benefits of Tripolium pannonicum: Antimicrobial, Antioxidant, and Prebiotic Properties With Phytochemical Insights
Authors: Aydın Betül 
Published: December 2024

ABSTRACTThis study investigates the multifaceted potential of Tripolium pannonicum methanolic extract, focusing on its antimicrobial, antioxidant, and prebiotic properties alongside a comprehensive phytochemical analysis. The antioxidant capacity of the methanolic extract was demonstrated through 2,2‐diphenyl‐1‐picrylhydrazyl radical scavenging and iron ion chelating assays, revealing an IC50 value of 0.073 mg/mL and 5.79 ± 0.04 mg/mL, respectively. Furthermore, the prebiotic activity of T. pannonicum was evaluated, showing enhanced growth of probiotic strains Lactobacillus plantarum and L. fermentum, compared to standard prebiotics, inulin, and fructooligosaccharides. The study also identified 27 bioactive phytochemical compounds in the methanolic extract, including 5‐hydroxymethylfurfural and palmitic acid, which were further explored through molecular docking analyses, revealing significant interactions with the human pregnane X receptor. These findings underscore the potential of T. pannonicum as a sustainable health solution in both agricultural and medicinal contexts, warranting further exploration of its therapeutic applications and mechanisms of action.
Microstructure Optimization of Nickel–Nitrogen‐Doped Porous Nanofibers for Enhanced Electrochemical CO2 Reduction
Authors: Wang Yicheng , Zhang Qiyu , Wen Shuo , Wang Chenxu , Ayeza  , Zhang Yating , Hu Chao 
Published: December 2024

AbstractThe utilization of renewable energy for electrocatalytic CO2 reduction (CO2RR) represents a significant advancement in green carbon conversion technologies. Single atom catalysts (SACs) featuring a transition metal‐nitride‐carbon (M‐Nx‐C) architecture exhibit catalytic activity for the reduction of CO2 to CO. However, the impact of the morphology of carbon supports, particularly their pore structure, on the electrocatalytic performance of CO2RR warrants further investigation. In this study, we fabricated a series of Ni‐based SACs supported by porous carbon nanofibers through electrospinning and sacrificial template method. We examined variations in microstructure of these porous carbon nanofiber carriers at different pyrolysis temperatures and elucidated their effects on CO2RR catalytic performance. The catalyst obtained at 1000 °C demonstrated efficient electrocatalysis for converting CO2 to CO due to its large specific surface area, abundant hierarchical pore structure, and high content of Ni‐Nx species resulting from both the sacrificial template method and high‐temperature pyrolysis. A Faradaic efficiency exceeding 90% was sustained across potentials ranging from −0.7 V to −1.3 V (versus RHE), with a peak efficiency reaching 96.1% at −1.0 V (versus RHE). Kinetic analysis indicated that this sample exhibited the highest reaction kinetics alongside minimal charge transfer resistance.
The Designs and Applications of Tetraphenylethylene Macrocycles and Cages
Authors: Li Dong‐Mi , Zuo Ruhai , Wang Jinhua , Le Zhiping 
Published: December 2024

AbstractMacrocycles and cages are very attractive for the development of functional materials due to their unique inner cavities. Building blocks with interesting functions and synthetic conveniences are especially attractive. Tetraphenylethylene (TPE) is such an entity with C2 symmetry and tetrakis‐functional groups easily modifiable. As a typical aggregation‐induced emission (AIE) active compound, TPE perfectly unites the functions of fluorescence and structural building blocks together. The unique marriage of the two roles into one component makes TPE an ideal platform for the development of functional molecular systems including macrocycles and cages. The TPE macrocycles and cages are not merely a simple combination of those two but also generate added values unseen in either component alone. The fluorescence properties of TPE in macrocycles/cages are greatly improved or modulated, which makes them more suitable for various applications compared to their linear counterparts. In this review, the chemistry and design principles of TPE macrocycles/cages are surveyed first. The unique properties of those compounds are also discussed to provide general guidance for their functionalization. A brief discussion of their applications focusing on the utilization of their unique fluorescence is also presented. In the last, outlooks and future perspectives of TPE macrocycles/cages are provided for further developments.