bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case study of an influenza vaccination program for health care workers in Vietnam
Authors: Ha Nga , Nguyen Thoa Thi Minh , Nguyen Tung Xuan , Tran Phu Dac , Nguyen Hang Minh , Ha Van Thi Cam , Lafond Kathryn E. , Seward Jane F. , McFarland Jeffrey W. , Chu Susan Y. 
Published: August 2020

Abstract
Background: In 2017, the Vietnam Ministry of Health conducted a demonstration project to introduce seasonal influenza vaccination to health care workers. A total of 11,000 doses of influenza vaccine, single-dose prefilled syringes, were provided free to HCWs at 29 selected hospitals, clinics, and research institutes in four provinces: Hanoi, Khanh Hoa, Dak Lak and Ho Chi Minh City. Methods: Before the campaign, a workshop was organized to discuss an implementation plan including technical requirements, cold chain, uptake reporting, and surveillance for adverse events following immunization. All sites distributed communication materials and encouraged their staff to register for vaccination. Following immunization sessions, sites sent reports on uptake and adverse events following immunization. Left-over vaccine was transferred to other sites to maximize vaccine use. Results: The average uptake was 57% for all health care workers, with 11 sites achieving 90% and above. These 11 sites were small with less than 500 staff, including 5 primary hospitals, 3 preventive medicine units, and 2 referral hospitals. Among the six biggest sites with over 1,000 staff, four sites had the lowest uptake (14%-47%). Most of the high-uptake sites were from the central to the south; only one site, a referral hospital, was from the north. After redistribution of left-over vaccine, only 130 vaccine doses (1.2%) were not used and destroyed. Based on factors that affected uptake, including registration levels, differing communication strategies, availability of vaccination, and commitment by health facility leaders, we recommended ways to increase health care worker coverage; recommendations to improve reporting adverse events following immunization were also made.Conclusions: The project demonstrated that it was feasible to conduct influenza vaccination campaigns among health care workers in Vietnam. Improvements in promotion of registration, more intense pre-planning, especially at larger facilities, and wider, more consistent availability of communication materials will result in increased efficiency and coverage in this program’s future expansion.
Toe flexor strength is associated with mobility in older adults with pronated and supinated feet but not with neutral feet
Authors: Kusagawa Yuki , Kurihara Toshiyuki , Imai Aiko , Maeo Sumiaki , Sugiyama Takashi , Kanehisa Hiroaki , Isaka Tadao 
Published: August 2020

Abstract
Background: Older adults are known to have more pronated foot posture and decreased toe flexor strength (TFS), as well as decreased mobility in daily life compared to young adults. Although foot posture is reported to be an influential factor for walking biomechanics in young adults, there is less information on this subject in older adults. Age-related reduction in TFS is shown to be associated with impairments of functional performance, but it is poorly understood whether foot posture influences the relationships between TFS and functional performances. Therefore, the present study aimed to elucidate this concern by examining older women. Methods: Seventy community-dwelling older women (76.8 ± 4.4 years) voluntarily participated in this study. Foot posture was evaluated by the 6-item foot posture index (FPI). Based on the FPI score, participants were allocated to pronated, neutral, or supinated group (n = 33, 26, and 11, respectively). TFS was assessed using a toe grip dynamometer in a seated position. Scores of 30-second chair stand, timed up-and-go, 5-m comfortable-speed walking, and static balance tests were determined to evaluate functional performances. Pearson’s correlation coefficients were computed to examine the relationships between TFS and functional performances in each group. Results: TFS positively correlated with comfortable walking speed in the pronated (r = 0.37, p = 0.03) and supinated (r = 0.76, p < 0.001) groups, but not in the neutral group (r = 0.17, p = 0.42). For the two significant relationships, an analysis of covariance showed that there was no significant difference between the pronated and supinated groups in the slopes of the regression lines, suggesting a similar relative contribution of TFS to comfortable walking speed between the two groups. In addition, TFS tended to negatively correlate with timed up-and-go time in the pronated (r = -0.32, p = 0.07) and supinated (r = -0.56, p = 0.08) groups, and positively correlate with 30-second chair stand score in the pronated group (r = 0.31, p = 0.08). Conclusions: The present study indicates that TFS would be associated with mobility, walking performance in particular, in older women with pronated and supinated feet but not with neutral feet.
Psychological impact of an epidemic/pandemic on the mental health of healthcare professionals: a rapid review
Authors: Stuijfzand Suzannah , Deforges Camille , Sandoz Vania , Sajin Consuela-Thais Consuela-Thais , Jaques Cécile , Elmers Jolanda , Horsch Antje 
Published: August 2020

Abstract
Background: Epidemics or pandemics, such as the current Coronavirus Disease 2019 (COVID-19) crisis, pose unique challenges to healthcare professionals (HCPs). Caring for patients during an epidemic/pandemic may impact negatively on the mental health of HCPs. There is a lack of evidence-based advice on what would be effective in mitigating this impact. Objectives: This rapid review synthesizes the evidence on the psychological impact of pandemics/epidemics on the mental health of HCPs, what factors predict this impact, and the evidence of prevention/intervention strategies to reduce this impact. Method: According to rapid review guidelines, systematic searches were carried out in Embase.com, PubMed, APA PsycINFO-Ovid SP, and Web of Science (core collection). Searches were restricted to the years 2003 or later to ensure inclusion of the most recent epidemic/pandemics, such as Severe Acute Respiratory Syndrome (SARS). Papers written in French or English, published in peer-reviewed journals, and of quantitative design using validated measures of mental health outcomes were included. Of 1308 papers found, 50 were included. The full protocol for this rapid review was registered with Prospero ( reg.no. CRD42020175985). Results: Results show that exposed HCPs working with patients during an epidemic/pandemic are at heightened risk of mental health problems in the short and longer term, particularly: psychological distress, insomnia, alcohol/drug misuse, and symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, burnout, anger, and higher perceived stress. These mental health problems are predicted by organizational, social, personal, and psychological factors and may interfere with the quality of patient care. Few evidence-based early interventions exist so far. Discussion: HCPs need to be provided with psychosocial support to protect their mental wellbeing if they are to continue to provide high quality patient care. Several recommendations relevant during and after an epidemic/pandemic, such as COVID-19, and in preparation for a future outbreak, are proposed.
Probability Bankruptcy Using Support Vector Regression Machines
Authors: Manurung Adler Haymans , Suhartono Derwin , Hutahayan Benny , Halimawan Noptovius 
Published: August 2020

Abstract
Bankruptcy is a decision made by a court after examining the assets and liabilities of individuals even businesses in which they are not able to pay their bills. Due to the importance of prevent bankruptcy to be happened in such business, a calculation which can predict probability bankruptcy is necessary. This paper aims to investigate probability bankruptcy using Support Vector Regression. There are 6 variables for 2016 to 2018 period coming from 17 coal mining companies from Indonesia. The model built by using Support Vector Regression indicates a good performance because it has the highest coefficient of determination.
Ceramic bricks containing Ni ions from contaminated biomass used as an adsorbent
Authors: Simón Daiana , Quaranta Nancy , Gass Sebastián , Procaccini Raúl , Cristóbal Adrián 
Published: August 2020

Abstract
This article shows how pine sawdust residues can be used to adsorb nickel ions from synthetic solutions and then to produce porous bricks for civil construction using a mixture of natural clay and biomass containing the adsorbed metals. The adsorption tests were performed by mixing NiCl2 solutions with pine sawdust during a fixed stirring period of 24 h. The set was filtered and the filtrate was analysed. Highest efficiency adsorbate/adsorbent ratio was 1 mol L-1 of NiCl2 solution and 20 g L-1 of pine sawdust. This was the contaminated biomass sample used in the manufacture of the bricks. This paper analyses the properties of the bricks achieved and compares them with bricks without added biomass, porous bricks containing zinc and commercial bricks. The obtained values ​​of bulk density (apD), apparent specific weight (aspW), apparent porosity (apP), water absorption (H2OAbs), apparent volume (apV), weight loss on ignition (LOI), compression fracture stress (σstr), flexural modulus of rupture (MOR) and retention efficiency (RE), demonstrate that the ceramic pieces obtained are optimal for construction.
Development of a national survey on foot involvement among people with psoriatic arthritis in Australia using a best practice approach: A survey development protocol
Authors: Carter Kate , Walmsley Steven , Rome Keith , Turner Deborah E. 
Published: August 2020

Abstract
Background Limited research to date has defined the nature and extent of foot involvement in a psoriatic arthritis-specific population in Australia and the scale of the problem remains unclear. Survey research provides the ideal opportunity to sample a large population over a wide geographical area. Although quality criteria for survey research have been developed, research shows that adherence is low and that survey studies are poorly reported in peer-reviewed survey articles, which limits the ability to inform future survey design. The objective of this paper was to develop a national survey about foot involvement in people with psoriatic arthritis using a best practice approach. This is a methods paper for the development of survey research.Methods A systematic, multi-stage process of survey development was undertaken, which comprised 3 phases: 1) the generation of the conceptual framework and survey content; 2) the development of the survey and pre-testing and 3) development of the survey dissemination strategy. A survey best practice approach was adopted using iterative pre-testing techniques, which included; cognitive debriefing, cultural sensitivity review, survey design expert validation, subject expert validation and pilot testing. Targeted postal and online survey dissemination strategies were developed a priori to optimise the response rates anticipated.Results A 59-item survey with 8 sections was developed. Findings demonstrated a high survey response (n=649), high data completeness (83% of respondents reached the end of the survey) and low rates of missing data (below 5% for 95% of respondents). Extensive survey pre-testing among the target population, health professionals and experts improved the overall quality, content validity, functioning and representativeness of the survey instrument, which optimised potential response rates. Clear audit trails that mapped the analytical process at each stage substantiated the rigour of the survey development methods. Robust strategies for sampling, survey dissemination and community engagement were deemed to have made a powerful contribution to response rates and the scale of information collected.Conclusions Robust patient-centred methods in survey design were used to create a novel, high-quality survey to comprehensively evaluate psoriatic arthritis-related foot involvement. Transparent and precise description of the survey design and dissemination methods provides useful information to other researchers embarking on survey design in healthcare.
Effects of Ferula assa-foetida on clinical, hormonal and ultrasound parameters in young girls with polycystic ovary syndrome: a randomized, placebo controlled, triple-blinded
Authors: Ghavi Fatemeh , abdolahian somayeh , Shakeri Fatemeh , Taebi Mahboubeh 
Published: August 2020

Abstract
Background: Polycystic ovarian syndrome is the most common endocrine disorder in reproductive aged women. As a result of side effect of pharmaceutical medications women are interested in using alternative medicines to treat. To determine the comparative effects of Ferula assa-foetida on androgenic hormone levels and ovarian features in patient with polycystic ovarian syndrome (PCOS). Methods: In this triple-blinded controlled clinical trial, 34 student participants were randomly divided in two groups. Intervention group received 100 mg of oleo-gum resin of Ferula assa- foetida, control group received oral paraffin (Placebo) twice daily for 3 months. The efficacy of this herbal medicines was measured after the 3-month intervention. Hormonal assay for evaluating Testosterone, DEHAS, Prolactin, TSH, FSH, LH levels and also trans abdominal ultrasound for evaluating ovarian volumes, number of follicles of both ovaries, and endometrial thickness. Were measured before and after the study. Results: In this study, significant changes in DEHAS and TSH level were observed (p value<0.03). The greatest reduction in the number of ovarian follicles was reported in the Ferula group (p value <0.00). Conclusion: Use of Ferula assa-foetida can be effected in decrease of DHEAS, TSH levels, and ovarian follicles number in young girls with PCOS.Trial registration: the Iranian Randomized Clinical Trial (IRCT2016040427207N1).url: https://www.irct.ir/trial/22343
The experiences of individuals with cervical spinal cord injury and their family during post-injury care in non-specialised and specialised units in UK
Authors: McRae Jackie , Smith Christina , Emmanuel Anton , Beeke Suzanne 
Published: August 2020

Abstract
Background Individuals with acute cervical spinal cord injury require specialised interventions to ensure optimal clinical outcomes especially for respiratory, swallowing and communication impairments. This study explores the experiences of post-injury care for individuals with cervical spinal cord injury and their family members during admissions in specialised and non-specialised units in the United Kingdom.Methods Semi-structured interviews were undertaken with individuals with a cervical spinal cord injury and their family member, focussing on the experience of care across units. Eight people with spinal cord injury levels from C2 to C6, were interviewed in their current care settings. Six participants had family members present to support them. Interviews were audio-recorded and transcribed with data inputted into NVivo for thematic analysis.Results The study identified six themes from the participant interviews that highlighted different experiences of care in non-specialised and specialised settings. A number of these were related to challenges with the system, whilst others were about the personal journey of recovery. The themes were titled as: adjustment, transitions, “the golden opportunity”, “when you can’t eat”, communication, and “in the hands of the nurses and doctors”.Conclusions Whilst participants reported being well cared for in non-specialised units, they felt that they did not receive specialist care and this delayed their rehabilitation. Participants were dependent on healthcare professionals for information and care and at times lost hope for recovery. Staff in non-specialised units require training and guidance to help provide support for those with dysphagia and communication difficulties, as well as reassurance to patients and families whilst they wait for transfer to specialised units.
Analysis of the Effect of Prognosis Factors for Breast Cancer
Authors: Deka Mrinal , Bhattacharjee Dibyojyoti 
Published: August 2020

Abstract
Background: The idea of Prognosis factor is based on the variables that can be used to assess the chance of recovery from a disease. It is also considered as the prior knowledge about any disease before treatment. The concept is applied to the cancer patients to get an idea of how cancer will affect the body and how it will respond to the therapies. Method: In this paper, selective prognostic factors (Age, Node and Tumour size) are analysed by logistic regression in patients who are suffering from Breast cancer based on data collected from Cachar Cancer Hospital and Research Centre, Silchar, Assam, India. Results: The study claims that there are 50.1 percent and 65.8 percent chance of remission of cancer for patients of age above 50 in case of breast cancer with below poverty line and above poverty line respectively. The present study has focused on this cut-off value of 2 cm as the determining prognostic factor in relation to tumour size. Thus, the chance of remission from cancer is 22.3 percent and 34.7 percent for below poverty line and above poverty line patients respectively, if tumour size is greater than 2 cm.It also endeavours to ascertain that there are 10.9 percent and 18.1 percent chances of remission of cancer, if the disease has metastasized to regional lymph nodes, with below poverty line and above poverty line respectively.Conclusion: The parameters viz. Tumour size and Node status, which measure the stage of the cancer patients, are significant prognostic factors that help in predicting tumour behaviour and survival outcomes for breast cancer patients.
Imbalanced Sensory Eye Dominance of Surgically Aligned Late-onset Acute Acquired Concomitant Esotropes with normal stereopsis
Authors: Yao Zhimo , Yu Huanyun , Zhang Junxiao , Chen Bo , Yu Xinping 
Published: August 2020

Abstract
Background: Adults with late-onset acute acquired concomitant esotropia (AACE) have chance to develop normal binocular functions including a balanced ocular dominance before the onset of esotropia. For most patients, strabismus surgery re-establishing the ocular alignment indeed effectively restore stereopsis and visual acuity to the normal level. However, it is unclear whether they have already acquired balanced two eyes.Methods: 11 surgically aligned patients with AACE (24.3 ± 1.5 years; mean ± SE) and 14 adults with normal vision (26.1±1.2 years) participated in our experiments. All patients had normal binocularity and stereopsis. Using binocular phase combination paradigm, sensory eye dominance was quantified as the interocular contrast ratio, termed balance point, at which the contribution of each eye to the perception of cyclopean grating were equal.Results: Normal controls had a mean balance point value close to unity (0.95±0.01), while AACE group exhibited evident binocular imbalance (0.76±0.05), which was significantly different from control group (t (10.45) = -3.485, p = 0.006) . The balance point value didn’t depend on the interval from AACE onset to strabismus surgery (r = -0.357, p = 0.281) or the interval from the surgery to examination of sensory eye dominance (r = -0.105, p = 0.759).Conclusions: Although strabismus surgery effectively straightened AACE patients’ ocular alignment and even conferred them normal stereopsis, late-onset AACE patients’ two eyes were still not balanced. These results indicated that binocular imbalance might be a risk factor for adult AACE.
Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice
Authors: Hashikawa-Hobara Narumi , Mishima Shuta , Okujima Chihiro , Shitanishi Youdai , Hashikawa Naoya 
Published: August 2020

Abstract
The relationships among neuropeptide, calcitonin gene-related peptide (CGRP), and memory formation remain unclear. Here, we showed that the intracerebroventricular administration of CGRP impaired the traumatic fear memories, in a widely studied animal model of post-traumatic stress disorder. We found that CGRP administration suppressed fear memory by increasing neuronal PAS domain protein 4 (Npas4), phosphorylated histone deacetylase 5 (HDAC5), and protein kinase D (PKD). We also discovered that Npas4 knockdown inhibited CGRP-mediated fear memory. CGRP decreased the binding between HDAC5 and the Npas4 enhancer site and increased the binding between acetylated histone H3 and the Npas4 enhancer site. The pharmacological inhibition or knockdown of PKD attenuated the CGRP-mediated impairment of fear memory and the increased phosphorylation of HDAC5 and Npas4 expression. Our findings demonstrated that the CGRP-PKD pathway was associated with the histone H3 acetylation-Npas4 pathway. These results suggested a novel function for CGRP on fear memory, through epigenetic regulation.
Newly Modified Descemetopexy Method in Descemet’s Membrane Detachment and Prognostic Analysis: A Systematic Review
Authors: Shen Zhan , Peng Rongmei , Xiao Gege , Hong Jing 
Published: August 2020

Abstract
BackgroundTo present a newly modified descemetopexy method and investigate the most determinative factor in the prognosis of Descemet’s membrane detachment (DMD). MethodsThis was a retrospective review of 37 patients (38 eyes) treated with the newly modified descemetopexy method. This surgical method was combined with the vacuum technique to pump supra-Descemet’s fluid. After reviewing and screening, we enrolled 31 patients (32eyes). We evaluated outcomes using the anatomical reattachment of DM [anatomical success (AS)] and the resolution of corneal oedema [functional success (FS)]. Donor characteristics, including sex, age, the presence of diabetes, ocular history, DMD duration, DMD grade, were analysed. Patients were divided into two groups according to whether FS was achieved. Univariate and multi-factor logistic regression analyses were adopted to evaluate factors contributing to the prognosis of DMD. ResultsAS was achieved in 31 eyes (96.9%), and FS was achieved in 21 eyes (65.6%). The univariate analysis showed that both the DMD grade (P=0.029) and DMD duration (P=0.004) affect the prognosis of DMD. The multiple logistic regression analysis indicated that the DMD duration was the dominant factor (P=0.006). No significant difference was found in the DMD grade, sex, age, presence of diabetes, presence of glaucoma or DMD-originating surgery between the two groups.ConclusionsDescemetopexy combined with the vacuum technique can be used to deal with DMD. The DMD duration is the dominant factor affecting the activity of endothelial cells and the final prognosis.