bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards a translationally-independent RNA-based synthetic oscillator using deactivated CRISPR-Cas
Authors: Kuo James , Yuan Ruoshi , Sánchez Carlos , Paulsson Johan , Silver Pamela A. 
Published: May 2020

AbstractIn synthetic circuits, CRISPR-Cas systems have been used effectively for endpoint changes from an initial state to a final state, such as in logic gates. Here, we use deactivated Cas9 (dCas9) and deactivated Cas12a (dCas12a) to construct dynamic RNA ring oscillators that cycle continuously between states over time in bacterial cells. While our dCas9 circuits using 103-nucleotide guide RNAs showed irregular fluctuations with a wide distribution of peak-to-peak period lengths averaging ∼9 generations, a dCas12a oscillator design with 40-nucleotide CRISPR RNAs performed much better, having a strongly repressed off-state, distinct autocorrelation function peaks, and an average peak-to-peak period length of ∼7.5 generations. Along with free-running oscillator circuits, we measure repression response times in open-loop systems with inducible RNA steps to compare with oscillator period times. We track thousands of cells for 24+ hours at the single-cell level using a microfluidic device. In creating a circuit with nearly translationally-independent behavior, as the RNAs control each others’ transcription, we present the possibility for a synthetic oscillator generalizable across many organisms and readily linkable for transcriptional control.
Landscaping health-care system using functional records management activities
Authors: Marutha Ngoako Solomon 
Published: May 2020

Purpose
The paper sought to investigate the landscaping of electronic system through the use of the functional patient’s records management activities. The rationale is to share views and guide organisations that are struggling with providing specification for a functional records management system.

Design/methodology/approach
The study used qualitative approach to apply the literature in supporting the views about landscaping electronic system using functional patient’s records management activities.

Findings
The study revealed that without consideration of records management activities the likelihood is that the system may be not properly functional. The best way to landscape electronic system for records management is using records management activities. This will assist in avoiding critical omission for inclusion of all records management system operational activities.

Originality/value
The paper is proposing a new way of landscaping the electronic system by using the records management functional activities. It also provides a framework to guide the implementers or electronic system developers. The paper was partially extracted from the author’s Ph.D. thesis completed in 2016, to develop a framework for landscaping the electronic system by using the records management functional activities.
Exploring strategic CSR communication on UAE banks' corporate websites
Authors: Georgiadou Effrosyni , Nickerson Catherine 
Published: May 2020

PurposeCommunicating CSR through corporate websites is one of the most effective ways for organizations to inform and engage stakeholders, earn legitimacy and reap the intangible and tangible benefits of practicing CSR. However, in emerging economies in the Middle East, online CSR disclosure remains limited while corporate websites are not used effectively as strategic tools. This study explores online CSR communication (CSRC) by banks in the dynamic, emerging economy of the United Arab Emirates.Design/methodology/approachThe study uses an adaptation of the analytical framework used by Chaudhri and Wang (2007) to examine the prominence and extent of the CSR information on the corporate websites of domestic and global banks in the UAE. It further compares domestic and global banks' CSRC patterns as well as domestic/government-owned versus private banks and conventional versus Islamic banks.FindingsAbout 70% of the domestic banks in the UAE provide information about their CSR activities. CSR information is moderately to highly prominent for the majority of the domestic banks, but the extent of the information presented is minimal (1–2 pages). Domestic/government-owned and conventional banks communicate their CSR more prominently and extensively than private and Islamic banks. Domestic/government-owned banks tend to follow the CSRC patterns observed in global banks.Originality/valueDespite the increasingly important role of the United Arab Emirates within the Middle East as well as on the global business arena, very little is known about whether and how companies in the country approach CSR. This is the first study focusing on CSRC within the entirety of a single business sector within the United Arab Emirates.
Invention commercialization among Russian scientists: bridging the gap between ideational and material realms
Authors: Sadigov Turkhan 
Published: May 2020

PurposeThe purpose of this paper is twofold. First, the article explores an understudied side of invention commercialization–the rejection of business as something “dirty” among Russian scientists. As such, the paper contributes to the individual-level explanations of innovation promotion, hence balancing extant literature's excessive focus on institutional explanations. Second, the article suggests that Russian scientists' rejection of business is rooted in broader Russian work ethics rift between “material” and “ideational” aspects of life. As such, the paper shows how dominant collective values refract in the management practice of specific social class, i.e. of scientists.Design/methodology/approachTo analyze the rift between material and ideational aspects of Russian scientists' work, the article employs directed content analysis (DCA) of in-depth interviews with 45 Russian scholars. To address credibility bias of the research findings stemming from DCA, I further draw on the survey of existing studies, researches and polls highlighting Russian population attitudes toward the dichotomy between “material” and “ideal” realms.FindingsThis study argues that Russian scientists' likelihood of invention commercialization is positively associated with their ability to integrate in a personal psyche business and science as equally valuable facets of life.Originality/valueThe article identifies the three groups of scientists – opportunity-seekers, idealists and integrators – with different attitudes to invention commercialization. The article shows how policymakers should apply institutional incentives differently to each group of scientists to achieve higher rates of invention commercialization.
Competitive capabilities in knowledge-intensive services firms: strategic advantages of born globals in a peripheral region
Authors: Muñoz Guarasa Marta , Fischer Bruno Brandão 
Published: May 2020

Purpose
While the born global (BG) phenomenon has been well established in the literature, studies on accelerated internationalization of firms in the service sector have been scarce, particularly for the specific case of knowledge-intensive services (KIS). The purpose of this paper is to explore which competitive characteristics differentiate KIS BGs from other KIS firms in the context of a peripheral region.

Design/methodology/approach
The empirical focus of this study comprehends primary survey data from 250 Spanish KIS firms (Andalusia) that have been internationalized and analyzed through ordinal and ordinary least squares regressions. The authors address the “born-global effect” on five features of interest, namely, entry mode, technological capabilities, qualification of staff, external resources and quality of services.

Findings
Results suggest that KIS BGs in Andalusia perceive exports as a more relevant form of internationalization than its non-BG peers. Also, KIS BGs in Andalusia present higher levels of technological intensity. Differences in terms of staff qualification, access to extramural R&D resources and the quality of services could not be identified.

Research limitations/implications
The main limitation of this research concerns its cross-sectional character, thus hindering the evaluation of developmental trajectories taking place in the cohort under scrutiny. Such an approach would allow a better comprehension of the competitiveness dynamics in internationalized KIS firms. Also, because this assessment is geographically restricted to Andalusia, Spain, the authors recommend caution in establishing direct comparisons and appropriation of results for other regional/national contexts.

Practical implications
Recommendations for public policy include establishing the necessary infrastructures to encourage the technological development of KIS companies and provide support – through export promotion agencies, for instance – for early approximation with foreign markets. Taking into account the contributions of KIS firms for the development of a peripheral economy, this involves the need to establish instruments that provide strategic information to internationalize, as well as lines of funding for these companies.

Originality/value
Empirical evidence on KIS BGs is needed to fully grasp its differences to other internationalized service firms. The analysis within this specific domain represents an advance in the literature on this subject. Also, the context of peripheral regions – considering their economic differences to core areas – has been understudied. The elaboration and application of the survey have allowed the authors to have access to primary in-depth data and, therefore, to build a better understanding of KIS BGs in Andalusia, Spain.
Relationship between personality traits and digital literacy skills: a study of university librarians
Authors: Ahmed Shamshad , Rasheed Tariq 
Published: May 2020

Purpose
This study aims to examine the relationship between personality traits and digital literacy skills among university librarians of Punjab, Pakistan.

Design/methodology/approach
Five research hypotheses were established to achieve the study objectives. Two instruments; namely, “big five inventory (BFI)” scale of personality traits and a structured questionnaire of digital literacy skills (library literacy, computer literacy, tool literacy, information retrieval literacy and research support literacy) were used to collect the data. Pearson correlation test and correlation research design were used to examine the relationship between digital literacy skills and personality traits of university librarians.

Findings
The findings of the study revealed significant relationships between personality traits and all digital literacy skills. The study concluded that librarians having the extraversion trait are more inclined toward digital literacy skills and they can perform well in the libraries as compared to professionals with other traits.

Research limitations/implications
This study measures the digital literacy skills among the librarians of “higher education commission” recognized universities of Punjab, Pakistan. The study conclusions and findings are limited in scope to only the librarians of these universities. Such topic has no previous research.

Practical implications
This study has practical implication for university libraries, library associations, librarians and library professionals. The results of the study are also useful for librarians to acquire digital literacy skills, which are necessary in the current digital environment to manage the libraries.

Social implications
Library professionals can get digital literacy skills to face the challenges of digital age.

Originality/value
Some researchers examined the relationship of personality traits with the social networking sites, internet addiction, knowledge sharing behavior, information seeking behavior and academic performance. This study in particular identified the relationship of personality traits with the digital literacy skills, which are essential for managing the libraries. It helps libraries to find suitable library professionals and also help managers in assigning the duties based on these personality traits and digital literacy skills.
Age-specific survival in prostate cancer using machine learning
Authors: Doja M.N. , Kaur Ishleen , Ahmad Tanvir 
Published: May 2020

PurposeThe incidence of prostate cancer is increasing from the past few decades. Various studies have tried to determine the survival of patients, but metastatic prostate cancer is still not extensively explored. The survival rate of metastatic prostate cancer is very less compared to the earlier stages. The study aims to investigate the survivability of metastatic prostate cancer based on the age group to which a patient belongs, and the difference between the significance of the attributes for different age groups.Design/methodology/approachData of metastatic prostate cancer patients was collected from a cancer hospital in India. Two predictive models were built for the analysis-one for the complete dataset, and the other for separate age groups. Machine learning was applied to both the models and their accuracies were compared for the analysis. Also, information gain for each model has been evaluated to determine the significant predictors for each age group.FindingsThe ensemble approach gave the best results of 81.4% for the complete dataset, and thus was used for the age-specific models. The results concluded that the age-specific model had the direct average accuracy of 83.74% and weighted average accuracy of 79.9%, with the highest accuracy levels for age less than 60.Originality/valueThe study developed a model that predicts the survival of metastatic prostate cancer based on age. The study will be able to assist the clinicians in determining the best course of treatment for each patient based on ECOG, age and comorbidities.
Automatic evaluation of online learning interaction content using domain concepts
Authors: Wu Di , Wu Lei , Palmer Alexis , Kinshuk Dr , Zhou Peng 
Published: May 2020

PurposeInteraction content is created during online learning interaction for the exchanged information to convey experience and share knowledge. Prior studies have mainly focused on the quantity of online learning interaction content (OLIC) from the perspective of types or frequency, resulting in a limited analysis of the quality of OLIC. Domain concepts as the highest form of interaction are shown as entities or things that are particularly relevant to the educational domain of an online course. The purpose of this paper is to explore a new method to evaluate the quality of OLIC using domain concepts.Design/methodology/approachThis paper proposes a novel approach to automatically evaluate the quality of OLIC regarding relevance, completeness and usefulness. A sample of OLIC corpus is classified and evaluated based on domain concepts and textual features.FindingsExperimental results show that random forest classifiers not only outperform logistic regression and support vector machines but also their performance is improved by considering the quality dimensions of relevance and completeness. In addition, domain concepts contribute to improving the performance of evaluating OLIC.Research limitations/implicationsThis paper adopts a limited sample to train the classification models. It has great benefits in monitoring students’ knowledge performance, supporting teachers’ decision-making and even enhancing the efficiency of school management.Originality/valueThis study extends the research of domain concepts in quality evaluation, especially in the online learning domain. It also has great potential for other domains.
An integrated understanding of academics knowledge sharing behaviour
Authors: Rahman Muhammad Sabbir , Abdel Fattah Fadi Abdel Muniem , Hassan Hasliza , Haque Tayeenul 
Published: May 2020

Purpose
The purpose of this study is to examine the underlying functions of sense of spirituality (SS), emotional intelligence (EI) and perceived work environment (PWE) towards knowledge sharing behaviour (KSB) among the academic staff of higher learning institutions (HLIs) through a comparative investigation. This study extends the investigation by examining the relationship between SS and KSB through the mediating role of EI. The moderating role of PWE between SS and KSB was also tested.

Design/methodology/approach
The sample comprised 300 responses from 150 Bangladeshi and 150 Malaysian academic staff of public and private HLIs. Convenient sampling tools were used. Structural equation modelling (SEM) was used to analyse the proposed model and hypotheses. The study explains the differences and similarities in KSB practices concerning SS, EI and PWE of the academic staff from the two countries’ HLIs.

Findings
The results support the direct positive effects of SS on KSB. The two data sets also support the indirect effects of SS on KSB through the mediation of EI. However, the results indicate that SS only promoted KSB among individuals with high levels of PWE in their respective institutions. For individuals with low levels of PWE, SS did not affect KSB.

Practical implications
The management of HLIs should engage their experiences and those of newly hired academic staff in the KSB process. However, in facilitating KSB culture among the academic staff, HLIs need to foster the staff’s SS, which ultimately improvises the EI to strongly influence KSB. The management of HLIs understands that SS may be inefficient in promoting KSB among employees with low PWE. Authorities of HLIs need to facilitate a quality work environment to enhance the association between SS and KSB.

Originality/value
This study is one of the initial attempts to investigate KSB by considering SS, EI and PWE in the context of Bangladesh and Malaysia HLIs. The findings of the study can serve as inputs to HLIs in developing best practices across KSB dimensions and improving academic staff performance.
Magnus effect for roll-decoupled canards on a spinning body of revolution
Authors: Klatt Daniel , Mielke Alina , Mundt Christian 
Published: May 2020

Purpose
Spinning slender bodies are affected by lateral Magnus forces and moments when exposed to cross-flow. The effects occurring for spinning bodies of revolution in combination with stabilising or control surfaces such as canards are not yet fully explained. Therefore the present work aims to investigate the phenomena arising from the interactions of a roll-decoupled guidance unit with a spinning rear body are investigated.

Design/methodology/approach
A generic tangential-ogive-cylinder projectile equipped with deflectable canards on a roll-decoupled nose is investigated by means of 3D Reynolds-averaged Navier–Stokes simulations at Mach number 2 for angles of attack up to 22 degrees. Different canard deflection angles up to 9 degrees are considered. Global aerodynamic coefficients as well as local flow fields are analysed to explain the interactions occurring between the roll-decoupled guidance unit and the spinning rear body.

Findings
The deflected canards lead to flow interactions resulting in lateral forces and moments even without a spinning motion of the rear part. Depending on the canard deflection angles, these forces act in or against the direction of the classical Magnus effect. For angles of attack smaller than 10 degrees it is possible for the current body geometry to directly superpose the lateral effects resulting from the fins for the non-spinning model with those occurring for the non-finned but spinning model to obtain the total forces and moments acting on a spinning model with canted canards. However, the lateral effects generated on the guidance unit itself are insignificant compared to the canard-induced effects on the rear body.

Originality/value
A detailed analysis of the interaction effects arising from a decoupled guidance unit containing canards with a non-spinning/spinning rear body is performed and the underlying phenomena are revealed.
A statistical approach to identify asynchronous extreme events for multi-regional energy system models
Authors: Minh Khuong Phuong , Ü. Yilmaz Hasan , McKenna Russell , Keles Dogan 
Published: May 2020

Purpose
With the growing deployment of variable renewable energy sources, such as wind and PV and the increasing interconnection of the power grid, multi-regional energy system models (ESMs) are increasingly challenged by the growth of model complexity. Therefore, the need for developing ESMs, which are realistic but also solvable with acceptable computational resources without losing output accuracy, arises. The purpose of this study is to propose a statistical approach to investigate asynchronous extreme events for different regions and then assess their ability to keep the output accuracy at the level of the full-resolution case.

Design/methodology/approach
To extract the extreme events from the residual demands, the paper focuses on analyzing the tail of the residual demand distributions by using statistical approaches. The extreme events then are implemented in an ESM to assess the effect of them in protecting the accuracy of the output compared with the full-resolution output.

Findings
The results show that extreme-high and fluctuation events are the most important events to be included in data input to maintain the flexibility output of the model when reducing the resolution. By including these events into the reduced data input, the output's accuracy reaches the level of 99.1% compared to full resolution case, while reducing the execution time by 20 times.

Originality/value
Moreover, including extreme-fluctuation along with extreme-high in the reduced data input helps the ESM to avoid misleading investment in conventional and low-efficient generators.
Leading with humility in tumultuous times: evidence from the United States
Authors: McClellan Sara 
Published: May 2020

PurposeWicked problems, cross-sectoral and transregional collaborations, emerging technologies and calls for innovation generate exciting but unpredictable transformations in governance. Emerging research suggests humility, rather than certitude, represents a promising ethos for public leaders working to solve problems in tumultuous times. This study examines the nature, value and practice of humility in public administration (PA) leadership.Design/methodology/approachThis study reviews cross-disciplinary research on the nature and value of humility and emerging findings and debates on humility assessment measures. It analyzes discourse among graduate students in US PA classes and uses ethnographic analysis from workshops with local government leaders to identify institutional dynamics that may influence leaders' willingness to act with humility.FindingsFindings suggest that although PA students and leaders may value humility, they encounter institutional constraints related to public sector legitimacy and narratives about expertise and risk. The author proposes a framework to guide future research and practice in humility and public leadership.Research limitations/implicationsPotential constraints emerged from a modest study of courses and workshops; further research is required to test the prevalence of themes across public leadership environments.Practical implicationsPublic leaders, teachers and coaches may apply these practices and assessment measures to cultivate humility in PA classes and organizations.Originality/valueThis study is among the first to explore leadership humility with attention to how PA context may influence practice.