bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of chipping and impregnation of Scots pine heartwood with sulfite cooking liquor
Authors: Gard Timmerfors Jessica , Gandla Madhavi Latha , Sjölund Torbjörn , Jönsson Leif J. 
Published: November 2020

AbstractHeartwood and sapwood of Scots pine were procured and chipped using a newly developed pilot drum chipper, which for the heartwood resulted in a combined fraction of pin chips and fines of ~ 3%. Heartwood wood chips were processed using a set of 15 different reaction conditions that differed with respect to impregnation and cooking procedures. The result was evaluated with regard to absorption of impregnation liquid, pulp yield, fraction of reject, viscosity, kappa number, brightness, fiber properties, and chemical composition measured using two different techniques (compositional analysis using two-step hydrolysis with sulfuric acid and Py-GC/MS). The chemical analyses provided detailed information about how all main organic constituents of the wood, cellulose, hemicelluloses, and lignin, were affected by operational parameters. Inclusion of a pressurized (9 bar) impregnation step resulted in a more efficient cook, but the duration of the impregnation step (five minutes and four hours were compared) was not decisive for the outcome. Omission of the impregnation step or using low-pressure impregnation resulted in high fractions of reject, poor delignification, and, with a cooking time of two hours, no advantages with regard to fiber length and fraction of fines. The results indicate that the conditions used during impregnation, such as pressure, temperature, and acidity of impregnation liquid, warrant further attention in future studies.
The great Millennials’ trouble: leading or confused green generation? An Italian insight
Authors: Bonera Michelle , Codini Anna Paola , Miniero Giulia 
Published: November 2020

AbstractThe paper purpose is to investigate the green consumption behaviour of the Millennials generation. The paper aims to understand if all Italian Millennials are similar in terms of green consumption and if there are differences in adopting and consuming green products. As Millennials are considered the driving generation of the sustainable movement, thanks to their lifestyle and behaviours, our study tries to comprehend whether these consumers can be considered the leading “Green Generation”. We performed a cluster analysis, using the non-hierarchical method by applying the k-medium algorithm, segmenting Millennials. The segmentation was performed according to the reasons underlying and against green consumption. Then, green values and green consumer behaviour of the segments were analyzed. The results of our research reveal the existence of different clusters of Millennial consumers in terms of green attitude. Some confusion about green issues in the Millennials generation emerges, contrasting with the literature. Our results do not necessarily imply a negative attitude towards green values by Millennials, but different green attitudes among the clusters.
Do spatial interactions fuel the climate-conflict vicious cycle? The case of the African continent
Authors: Cappelli Federica , Conigliani Caterina , Costantini Valeria , Lelo Keti , Markandya Anil , Paglialunga Elena , Sforna Giorgia 
Published: November 2020

AbstractWe propose an analysis of the multiple linkages between violent conflicts, weather-related variables and socio-economic conditions based on an original geo-referenced database covering the entire African continent with a grid resolution of 1° × 1° for the period 1990–2016. We implement a dynamic spatial panel Durbin model that allows us: (1) confirming well-known mechanisms in violent conflicts analysis; (2) assessing the relevance of persistency of violence over time; (3) adding new insights related to the role of spatial relations associated to contagion. In particular, the spatial specification allows us quantifying the contagious effect across space, that persists in a radius of more than 300 km. Weather-related variables seem to play a prominent role in shaping contagion with different strength depending on the temporal horizon adopted. The main implications we derive are twofold: (1) adaptation policies designed for reducing vulnerability of local communities to climate change must be integrated with direct actions for peacekeeping in order to break the persistency of violence over time that is responsible for failures of the adaptation actions themselves; (2) synergies from simultaneous actions developed for different local communities must drive geographical coordination of integrated policies in order to capture the positive elements of cooperation associated to geographical spillovers while breaking violence contagion across neighbours.
Drastic decline in the endemic brown shrike subspecies Lanius cristatus superciliosus in Japan
Authors: KITAZAWA MUNEHIRO , SENZAKI MASAYUKI , MATSUMIYA HIROAKI , HARA SEIICHI , MIZUMURA HARUKA 
Published: November 2020

SummaryThe Brown Shrike Lanius cristatus breeds across a large portion of eastern Asia. One subspecies, L. c. superciliosus, is primarily endemic to Japan and was historically abundant throughout its breeding range. However, both local- and broad-scale studies documented a drastic population decline between the 1970s and 1990s, and the status of the taxon is currently unavailable in Japan. We conducted a nationwide survey to estimate the current population size and breeding range of this subspecies within Japan. We further compared our findings to the historical breeding ranges through a literature review. The total population size was estimated at 149 breeding pairs, and the current breeding range was estimated at 6,800 km2, indicating a 90.9% range contraction over the past century. Our study highlights the urgency of protecting remaining breeding habitats and establishing effective conservation strategies for L. c. superciliosus.
Aortic atresia with interrupted aortic arch and bilateral arterial ductus: a successful initial palliation
Authors: Rahmath Muhammed Riyas K. , Boudjemline Younes , Kamal Reema Y. 
Published: November 2020

AbstractA combination of aortic valve atresia and an interrupted aortic arch is a unique disease in which perfusion to the brain and myocardium depends on coexisting lesions or type of interruption. We report a case of aortic valve atresia with type B interrupted arch, bilateral arterial ductus in a neonate who was successfully palliated using a hybrid approach by placing stents in both arterial ductus and banding of branch pulmonary arteries.
Opportunities for intervention and innovation in school food within UK schools
Authors: Woodside JV , Adamson A , Spence S , Baker T , McKinley MC 
Published: November 2020

Abstract
We have recently been funded by the UK Prevention Research Partnership (UKPRP) to develop a UK school food network. The overarching aim is to build a community working towards a more health-promoting food and nutrition system in UK schools (primary and secondary). Here we describe the current status of school food research, including a review of the literature supporting the health-promoting schools approach and outline the opportunities for intervention and innovation establishment of the network present. Key potential school food research themes are described, and their prioritisation within the network, as well as network activities that have been planned, with the ultimate ambition of reducing socio-economic diet-related inequalities, and, consequently, non-communicable disease risk.
Evolution of the Southwest Australian Rifted Continental Margin During Breakup of East Gondwana: Results From International Ocean Discovery Program Expedition 369
Authors: Harry D. L. , Tejada M. L. G. , Lee E. Y. , Wolfgring E. , Wainman C. C. , Brumsack H.‐J. , Schnetger B. , Kimura J.‐I. , Riquier L. , Borissova I. , Hobbs R. W. , Jiang T. , Li Y‐X. , Maritati A. , Martinez M. , Richter C. , Tagliaro G. , White L. T. 
Published: November 2020

AbstractInternational Ocean Discovery Program Expedition 369 drilled four sites on the southwestern Australian continental margin, in the deep water Mentelle Basin (MB) and on the neighboring Naturaliste Plateau (NP). The drillsites are located on continental crust that continued rifting after seafloor spreading began further north on the Perth Abyssal Plain (PAP) between magnetochrons M11r and M11n (133–132 Ma), ending when spreading began west of the NP between chrons M5n and M3n (126–124 Ma). Drilling recovered the first in situ samples of basalt flows overlying the breakup unconformity on the NP, establishing a magnetostratigraphically constrained eruption age of >131–133 Ma, and confirming a minimal late Valanginian age for the breakup unconformity (coeval with the onset of PAP seafloor spreading). Petrogenetic modeling indicates the basalts were generated by 25% melting at 1.5 GPa and a potential temperature of 1380°C–1410°C, consistent with proximity of the Kerguelen plume during breakup. Benthic foraminiferal fossils indicate that the NP remained at upper bathyal or shallower depths during the last 6 Myr of rifting and for 3–5 Myr after breakup between India and Australia. The limited subsidence is attributed to heat from the nearby Kerguelen plume and PAP spreading ridge. The margin subsided to middle bathyal depths by Albian time and to lower bathyal (NP) or greater (MB) depths by late Paleogene time. Periods of rapid sedimentation accompanied a westward jump of the PAP spreading ridge (108 Ma), rifting on the southern margin (100–84 Ma), and opening of the southern seaway between Australia and Antarctica (60–47 Ma).
Two‐Point Mixing, Buoyancy Sorting, and Updraft Dilution in the RACORO Campaign
Authors: Wei Xin , Chan Pak Wah , Kuang Zhiming 
Published: November 2020

AbstractAircraft measurements of shallow cumulus cases from the Routine Atmospheric Radiation Measurement (ARM) Aerial Facility (AAF) Clouds with Low Optical Water Depths (CLOWD) Optical Radiative Observations (RACORO) campaign are studied in a transformed Paluch diagram. Previous studies have interpreted samples in Paluch diagrams in terms of two‐point mixing and buoyancy sorting. The two‐point mixing behavior is frequently seen in the RACORO observations and can be unambiguously distinguished from buoyancy sorting. The latter is not found in the RACORO observations and is also rare in a large‐eddy simulation (LES) of a RACORO case. As opposed to often assumed gradual dilution of updrafts, around half of the instances of two‐point mixing show no clear evidence of updraft dilution. We also find substantial spread in the properties of parcels that have adjusted to their level of neutral buoyancy and that a LES with horizontally homogeneous surface underestimates this spread. The inclusion of surface heterogeneity in the LES improves the agreement of its horizontal moisture variations with the aircraft measurements.
SABER Observations of Gravity Wave Responses to the Madden‐Julian Oscillation From the Stratosphere to the Lower Thermosphere in Tropics and Extratropics
Authors: Li Jintai , Lu Xian 
Published: November 2020

AbstractThe 17‐year SABER‐observed gravity wave (GW) temperature variances reveal significant responses of GWs to the Madden‐Julian Oscillation (MJO) over the middle atmosphere (30–100 km) in tropics and extratropics (45°S to 45°N) for boreal winter. The responses vary significantly with latitude but barely with altitude. From 20°S to 45°N, strong positive anomalies are found for MJO Phases 3–5, while negative anomalies for Phases 7–8. From 45–20°S, these patterns are reversed. The peak‐to‐peak differences (positive‐to‐negative anomalies) are ~6–16% relative to the seasonal mean. Comparison with MJO modulations on tropical convection and polar vortex suggests that GW responses in tropics may result from the modulation of GW source, while responses in northern extratropics may result from the modulation of polar vortex, which in turn modulates GW activities. These results highlight the importance of GWs to imprint the tropical MJO signals vertically to the middle atmosphere and horizontally to extratropical regions.
Benchmark Calculations of Radiative Forcing by Greenhouse Gases
Authors: Pincus Robert , Buehler Stefan A. , Brath Manfred , Crevoisier Cyril , Jamil Omar , Franklin Evans K. , Manners James , Menzel Raymond L. , Mlawer Eli J. , Paynter David , Pernak Rick L. , Tellier Yoann 
Published: November 2020

AbstractChanges in concentrations of greenhouse gases lead to changes in radiative fluxes throughout the atmosphere. The value of this change, the instantaneous radiative forcing, varies across climate models, due partly to differences in the distribution of clouds, humidity, and temperature across models and partly due to errors introduced by approximate treatments of radiative transfer. This paper describes an experiment within the Radiative Forcing Model Intercomparision Project that uses benchmark calculations made with line‐by‐line models to identify parameterization error in the representation of absorption and emission by greenhouse gases. Clear‐sky instantaneous forcing by greenhouse gases is computed using a set of 100 profiles, selected from a reanalysis of present‐day conditions, that represent the global annual mean forcing from preindustrial times to the present day with sampling errors of less than 0.01 W m−2. Six contributing line‐by‐line models agree in their estimate of this forcing to within 0.025 W m−2 while even recently developed parameterizations have typical errors 4 or more times larger, suggesting both that the samples reveal true differences among line‐by‐line models and that parameterization error will be readily identifiable. Agreement among line‐by‐line models is better in the longwave than in the shortwave where differing treatments of the water vapor continuum affect estimates of forcing by carbon dioxide and methane. The impacts of clouds on instantaneous radiative forcing are estimated from climate model simulations, and the adjustment due to stratospheric temperature changes estimated by assuming fixed dynamical heating. Adjustments are large only for ozone and for carbon dioxide, for which stratospheric cooling introduces modest nonlinearity.
Sensing the allosteric force
Authors: Bozovic Olga , Jankovic Brankica , Hamm Peter 
Published: November 2020

AbstractAllosteric regulation is an innate control in most metabolic and signalling cascades that enables living organisms to adapt to the changing environment by tuning the affinity and regulating the activity of target proteins. For a microscopic understanding of this process, a protein system has been designed in such a way that allosteric communication between the binding and allosteric site can be observed in both directions. To that end, an azobenzene-derived photoswitch has been linked to the α3-helix of the PDZ3 domain, arguably the smallest allosteric protein with a clearly identifiable binding and allosteric site. Photo-induced trans-to-cis isomerisation of the photoswitch increases the binding affinity of a small peptide ligand to the protein up to 120-fold, depending on temperature. At the same time, ligand binding speeds up the thermal cis-to-trans back-isomerisation rate of the photoswitch. Based on the energetics of the four states of the system (cis vs trans and ligand-bound vs free), the concept of an allosteric force is introduced, which can be used to drive chemical reactions.
RETRACTED ARTICLE: The association between early career informal mentorship in academic collaborations and junior author performance
Authors: AlShebli Bedoor , Makovi Kinga , Rahwan Talal 
Published: November 2020

AbstractWe study mentorship in scientific collaborations, where a junior scientist is supported by potentially multiple senior collaborators, without them necessarily having formal supervisory roles. We identify 3 million mentor–protégé pairs and survey a random sample, verifying that their relationship involved some form of mentorship. We find that mentorship quality predicts the scientific impact of the papers written by protégés post mentorship without their mentors. We also find that increasing the proportion of female mentors is associated not only with a reduction in post-mentorship impact of female protégés, but also a reduction in the gain of female mentors. While current diversity policies encourage same-gender mentorships to retain women in academia, our findings raise the possibility that opposite-gender mentorship may actually increase the impact of women who pursue a scientific career. These findings add a new perspective to the policy debate on how to best elevate the status of women in science.
Involvement of neutrophils in machineries underlying the rupture of intracranial aneurysms in rats
Authors: Kushamae Mika , Miyata Haruka , Shirai Manabu , Shimizu Kampei , Oka Mieko , Koseki Hirokazu , Abekura Yu , Ono Isao , Nozaki Kazuhiko , Mizutani Tohru , Aoki Tomohiro 
Published: November 2020

AbstractSubarachnoid hemorrhage due to rupture of an intracranial aneurysm has a quite poor prognosis after the onset of symptoms, despite the modern technical advances. Thus, the mechanisms underlying the rupture of lesions should be clarified. To this end, we obtained gene expression profile data and identified the neutrophil-related enriched terms in rupture-prone lesions using Gene Ontology analysis. Next, to validate the role of neutrophils in the rupture of lesions, granulocyte-colony stimulating factor (G-CSF) was administered to a rat model, in which more than half of induced lesions spontaneously ruptured, leading to subarachnoid hemorrhage. As a result, G-CSF treatment not only increased the number of infiltrating neutrophils, but also significantly facilitated the rupture of lesions. To clarify the mechanisms of how neutrophils facilitate this rupture, we used HL-60 cell line and found an enhanced collagenolytic activity, corresponding to matrix metalloproteinase 9 (MMP9), upon inflammatory stimuli. The immunohistochemical analyses revealed the accumulation of neutrophils around the site of rupture and the production of MMP9 from these cells in situ. Consistently, the collagenolytic activity of MMP9 could be detected in the lysate of ruptured lesions. These results suggest the crucial role of neutrophils to the rupture of intracranial aneurysms; implying neutrophils as a therapeutic or diagnostic target candidate.
Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort
Authors: Prasov Lev , Guan Bin , Ullah Ehsan , Archer Steven M. , Ayres Bernadete M. , Besirli Cagri G. , Wiinikka-Buesser Laurel , Comer Grant M. , Del Monte Monte A. , Elner Susan G. , Garnai Sarah J. , Huryn Laryssa A. , Johnson Kayla , Kamat Shivani S. , Lieu Philip , Mian Shahzad I. , Rygiel Christine A. , Serpen Jasmine Y. , Pawar Hemant S. , Brooks Brian P. , Moroi Sayoko E. , Richards Julia E. , Hufnagel Robert B. 
Published: November 2020

AbstractNanophthalmos is a rare condition defined by a small, structurally normal eye with resultant high hyperopia. While six genes have been implicated in this hereditary condition (MFRP, PRSS56, MYRF, TMEM98, CRB1,VMD2/BEST1), the relative contribution of these to nanophthalmos or to less severe high hyperopia (≥ + 5.50 spherical equivalent) has not been fully elucidated. We collected probands and families (n = 56) with high hyperopia or nanophthalmos (≤ 21.0 mm axial length). Of 53 families that passed quality control, plausible genetic diagnoses were identified in 10/53 (18.8%) by high-throughput panel or pooled exome sequencing. These include 1 TMEM98 family (1.9%), 5 MFRP families (9.4%), and 4 PRSS56 families (7.5%), with 4 additional families having single allelic hits in MFRP or PRSS56 (7.5%). A novel deleterious TMEM98 variant (NM_015544.3, c.602G>C, p.(Arg201Pro)) segregated with disease in 4 affected members of a family. Multiple novel missense and frameshift variants in MFRP and PRSS56 were identified. PRSS56 families were more likely to have choroidal folds than other solved families, while MFRP families were more likely to have retinal degeneration. Together, this study defines the prevalence of nanophthalmos gene variants in high hyperopia and nanophthalmos and indicates that a large fraction of cases remain outside of single gene coding sequences.
Strip width ratio expansion with lowered N fertilizer rate enhances N complementary use between intercropped pea and maize
Authors: Hu Falong , Tan Yan , Yu Aizhong , Zhao Cai , Fan Zhilong , Yin Wen , Chai Qiang , Cao Weidong 
Published: November 2020

AbstractMaize (Zea mays L.)/pea (Pisum sativum L.) strip intercropping is considered a promising cropping system to boost crop productivity. The 3-year (2009–2011) field experiment was conducted at Wuwei, northwest China, with two maize to pea strip width ratios (80:80 cm and 120:80 cm), each under three N fertilizer rates (0, 90 and 135 kg N ha−1 for pea, and 0, 300, and 450 kg N ha−1 for maize). The results showed that expanding maize to pea strip width ratio from 80:80 cm to 120:80 cm coupled with a reduction of N fertilizer rate intensified N competition and improved N compensation. The apparent N recovery and N utilization efficiency of intercropped pea with strip width ratio of 120:80 cm were increased by 8.0% and 8.9% compared to strip width ratio of 80:80 cm. Compared to high N rate, the two indicators of intercropped pea with lowered N rate were increased by 10.0% and 6.0%. For intercropped maize, the two indicators were increased by 6.8% and 5.1%, with strip width ratio of 120:80 cm compared to 80:80 cm. Also, they were improved by 9.7% and 11.5%, with lowered N rate compared to high N rate. Consequently, the grain yield of pea and maize in the 120:80 cm pattern was improved by 11.9% and 7.7% compared to 80:80 cm. We concluded that expanding maize to pea strip ratio coupled with N fertilizer reduction can optimize N complementary use.
Convolutional neuronal networks combined with X-ray phase-contrast imaging for a fast and observer-independent discrimination of cartilage and liver diseases stages
Authors: Stroebel Johannes , Horng Annie , Armbruster Marco , Mittone Alberto , Reiser Maximilian , Bravin Alberto , Coan Paola 
Published: November 2020

AbstractWe applied transfer learning using Convolutional Neuronal Networks to high resolution X-ray phase contrast computed tomography datasets and tested the potential of the systems to accurately classify Computed Tomography images of different stages of two diseases, i.e. osteoarthritis and liver fibrosis. The purpose is to identify a time-effective and observer-independent methodology to identify pathological conditions. Propagation-based X-ray phase contrast imaging WAS used with polychromatic X-rays to obtain a 3D visualization of 4 human cartilage plugs and 6 rat liver samples with a voxel size of 0.7 × 0.7 × 0.7 µm3 and 2.2 × 2.2 × 2.2 µm3, respectively. Images with a size of 224 × 224 pixels are used to train three pre-trained convolutional neuronal networks for data classification, which are the VGG16, the Inception V3, and the Xception networks. We evaluated the performance of the three systems in terms of classification accuracy and studied the effect of the variation of the number of inputs, training images and of iterations. The VGG16 network provides the highest classification accuracy when the training and the validation-test of the network are performed using data from the same samples for both the cartilage (99.8%) and the liver (95.5%) datasets. The Inception V3 and Xception networks achieve an accuracy of 84.7% (43.1%) and of 72.6% (53.7%), respectively, for the cartilage (liver) images. By using data from different samples for the training and validation-test processes, the Xception network provided the highest test accuracy for the cartilage dataset (75.7%), while for the liver dataset the VGG16 network gave the best results (75.4%). By using convolutional neuronal networks we show that it is possible to classify large datasets of biomedical images in less than 25 min on a 8 CPU processor machine providing a precise, robust, fast and observer-independent method for the discrimination/classification of different stages of osteoarthritis and liver diseases.