bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technofunctional quality assessment of soymilk fermented with Lactobacillus acidophilus and Lactobacillus casei
Authors: Ahsan Samreen , Khaliq Adnan , Chughtai Muhammad Farhan Jahangir , Nadeem Muhammad , Tahir Assam Bin , Din Amir Alaud , Ntsefong Godswill Ntsomboh , Shariati Mohammad Ali , Rebezov Maksim , Yessimbekov Zhanibek , Thiruvengadam Muthu 
Published: January 2021

AbstractThe current research work was carried out to evaluate the effect of three different varieties (NARC‐II, Williams 82, Ajmeri) of soybean along with single and coculture impact of Lactobacillus acidophilus and Lactobacillus casei on fermented soymilk. The periodically microbial and antioxidative activities of fermented soymilk were analyzed during the storage of 24 days. Moreover, the effect of fermentation on rheological and structural changes was examined along with isoflavone contents in fermented soymilk. Viability of cells and antioxidative activities were found to be significantly (P < 0.05) higher in fermented soymilk using mixed cultures. The rheological attributes demonstrated higher viscosity in coculture fermented soymilk. Scanning electron microscopic examination indicated that the growth characteristic of L. casei has a relatively more uniform texture and smaller pore size in comparison to L. acidophilus. Nevertheless, the combination of cultures exhibited precise pore formation with stronger cross‐links of soybean protein throughout the structure. Assessment of isoflavones exhibited higher values, for daidzein (20.87 ppm) in comparison to genistein (6.57 ppm), in Ajmeri‐based coculture soymilk. Conclusively, L. casei and L. acidophilous exhibited considerable antioxidant potential in the development of viscous, less porous, and rich in bioactive metabolites fermented soymilk, when used in combination and among varieties Ajmeri results it was the top of all. This suggests that the process evidence in this study could be recommended for high‐quality soymilk production.
Father involvement in infancy predicts behavior and response to chronic stress in middle childhood in a low‐income Latinx sample
Authors: Roby Erin , Piccolo Luciane R. , Gutierrez Juliana , Kesoglides Nicole M. , Raak Caroline D. , Mendelsohn Alan L. , Canfield Caitlin F. 
Published: January 2021

AbstractFathers’ involvement in early childhood is important for children's physical, emotional, and cognitive development, particularly in low‐income families. However, little is known about the longitudinal relations between early father involvement and children's later physiological responses to chronic stress and behaviors impacted by stress in the context of poverty. These issues are particularly important among Latinx immigrant families who face significant psychosocial and poverty‐related risk. In the current study, we examined the relationship between father involvement in infancy and physiological chronic stress in the middle childhood period, as measured through hair cortisol concentration (HCC), and several behavioral measures (attention problems, working memory) in a Latinx immigrant sample with low income. Father involvement in infancy predicted children's later HCC, and working memory in second to third grade. Father involvement also moderated the effect of HCC on working memory, such that increased HCC predicted better working memory when fathers were not involved. These findings suggest that the fathers’ involvement in infancy has lasting impacts on health and behavior and that associations between physiological and behavioral measures of stress may be moderated by differences in early father involvement.
Understand funding liquidity and market liquidity in a regime‐switching model
Authors: Chen Louisa , Shen Liya , Zhou Zhiping 
Published: January 2021

AbstractWe investigate the time‐varying relationship of funding liquidity (FL) and market liquidity (ML) in a Markov regime‐switching model. By using a comprehensive U.S. TRACE dataset, we provide strong evidence that FL and corporate bond ML are interlinked, and their impact on each other is highly regime‐dependent. We find that FL and ML exhibit a large‐and‐positive mutual impact when money market is tight and equity market is volatile. But in normal regimes, FL is found to have a negative impact on ML with a much smaller magnitude than those in stressed regimes. Furthermore, FL is more stable than ML with less regime changes. Our article offers insight on the important mechanism by which central banks can improve ML through the funding market.
Differences in susceptibility of HT‐29 and A549 cells to statin‐induced toxicity: An investigation using high content screening
Authors: Wei Guilin , Xue Lijuan , Zhu Yadi , Qian Xingkai , Zou Liwei , Jin Qiang , Wang Dandan , Ge Guangbo 
Published: January 2021

AbstractStatins are a group of hydroxymethylglutaryl coenzyme A reductase inhibitors that are used in the treatment of cardiovascular diseases. However, statins have been found to be cytotoxic, and many unexpected side effects have been reported in clinical applications. The susceptibilities of different cell lines toward statins are diverse, and the mechanisms of cytotoxicity remain unknown. Therefore, the present study aimed to investigate differences in the susceptibility to and mechanisms of statin‐induced cytotoxicity in two cell lines, HT‐29 and A549, using a high content screening‐based multiparametric toxicity assay panel. We found that the two cell types exhibited differing susceptibilities to the cytotoxic effects of the different statins. Additionally, the cytotoxicity was inconsistent between different statins in the two cell lines. Four statins with strong cytotoxicity decreased the viability of HT‐29 cells via the mitochondrial pathway, as evidenced by decreased mitochondrial membrane potential, and elevated mitochondrial mass, calcium release and cell apoptosis, and reactive oxygen species. In contrast, these four statins only induced a decrease in the mitochondrial membrane potential in A549 cells. The above results provide an objective reason for future evaluations of cytotoxic differences in cell types and the underlying mechanisms of cytotoxicity in different statins, and provide a good scientific basis for further research on countermeasures against statin‐induced cell injuries.
Thin submental artery perforator flap for upper lip reconstruction: A case report
Authors: Habibi Koohyar , Ganry Laurent , Luca‐Pozner Vlad , Atlan Michael , Qassemyar Quentin 
Published: January 2021

AbstractReconstruction of upper lip defects can be challenging even for experienced surgeons. In order to restore both function and morphology, the use of quality soft tissue is essential. To this effect, the most common solution is the use of local flaps, or, in extreme situations, a free flap. However, a thin cutaneous upper lip defect may require a different approach. Perforator flaps are versatile and may allow an efficient reconstruction of soft tissue defects using adjacent similar tissues, providing the benefit of “like with like” coverage. We present the case of a 41‐year‐old female with a 1 × 1.5 cm basal cell carcinoma of the right‐side upper lip, initially treated with a full thickness skin graft. Due to poor aesthetic and functional result, a thin submental artery perforator (SMAP) flap reconstruction was performed. Flaps' dimensions were 6 cm long and 4 cm wide and it was based on a perforator arising from the submental artery. Dissection was conducted above the platysma muscle, and the SMAP flap was transferred into the defect through a subcutaneous tunnel created below the mandible and posterior to the anterior belly of digastric muscle. The pedicle length of 6.5 cm was adequate for a tension free inset of the flap. Postoperative course was uneventful and the patient was discharged after 2 days. The 4‐month follow‐up showed a satisfying functional and aesthetic outcome with a concealed donor site scar. This report points out the coverage potential of the thin SMAP flap, which can be successfully used for a harmonious reconstruction in both color and texture of the upper lip.
Preparation of multifunctional hydrogels with pore channels using agarose sacrificial templates and its applications
Authors: Mao Jie , Yu Qi Jian , Wang Sui 
Published: January 2021

AbstractSmart hydrogel has been widely studied due to their unique response characteristics. Although many smart hydrogels have been developed, the preparation of high‐performance and multi‐responsive smart hydrogels remains a challenge. The application of developing new materials is also the valuable embodiment of materials, such as temperature sensors, thermal switches and anionic dye adsorption. In this study, poly(N‐isopropylacrylamide) (PNIPAM) hydrogel with pore channels was prepared using agarose as a sacrificial template, and a polyaniline network structure was introduced into hydrogel pore channels to endow the hydrogels with stable conductivity. This point can be confirmed by the Fourier transform infrared spectroscopy and scanning electron microscopy images of hydrogels. The decomposition temperature of hydrogels characterized by thermogravimetric analysis. Thermal response analysis and electrical performance testing found that PNIPAM hydrogel with pore channels exhibited enhanced temperature‐responsive swelling‐shrinkage properties and high conductivity (1.83 S m−1). Based on this unique property, we demonstrated the application of materials in thermal switching (response temperature ~33°C) and can be potentially applied to the temperature sensor and anionic dye adsorption.
Taking vision 20/20 to new heights
Authors: Bardin Billy B. , Kas Kathleen A. 
Published: January 2021

AbstractVision 20/20 was developed by the Center for Chemical Process Safety (CCPS) in 2013 as a forward‐looking initiative describing the characteristics of organizations with exceptional process safety performance. The CCPS Vision 20/20 incorporated five basic tenets: Committed Culture, Vibrant Management Systems, Disciplined Adherence to Standards, Intentional Competency Development, and Enhanced Applications of Lessons Learned. These tenets represent foundational elements that are essential for excellence in process safety and have been the basis for improved process safety performance in many companies, including Dow. As we end the year 2020, it is time to reflect on Vision 20/20 and the future of process safety over the next decade. Certainly, the five tenets of Vision 20/20 remain critical for sustained process safety performance. However, now is an appropriate time to consider how developing technology can drive new advances in process safety over the next decade. At Dow, the utilization of digital technologies is helping to take Vision 20/20 to new heights by providing tools, insights, and applications that improve process and personal safety as well as drive value delivery. Through the application of analytics, robotics, mobile tools, and overall data connectivity, Dow is driving improvements in inspections, reductions in confined space entries, greater unplanned event prevention, and improved reliability. The application of these emerging and applied digital tools sets the standard for beyond Vision 20/20 performance in operational safety and reliability.
Digitalization of Russian Education: Changing Actors and Spaces of Governance
Authors: Piattoeva Nelli , Gurova Galina 
Published: January 2021

AbstractThis chapter discusses the operation of digital education in relation to the changing governance of education in Russia. It examines how digitalization changes the character of traditional actors and enables new actors and actor assemblages to enter the scene of education governance and provision. It then looks at how datafication extends spaces of governance in both a topographical and a topological manner. Topographically, some practices of datafication follow established administrative structures enabling tighter vertical control over regions and education institutions by the federal authorities. But datafication also generates spaces that overcome topographical distance through relationality and connectedness. These manifest, first, in intensifying proximities to the global level of education governance bypassing the national authority, and, second, in the possibilities of intimate governance reaching into individual subjectivities.
Digital Art: A Sourcebook of Ideas for Conceptualizing New Practices, Networks and Modes of Self-Expression
Authors: Strukov Vlad 
Published: January 2021

AbstractThe chapter traces the evolution of digital art produced in the Russian Federation and in the Russian language by critically considering a number of case studies and re-conceptualizing historical periods. It takes into account technologies, institutions, individual artists and artistic networks, and modes of presentation, appreciation and re-contextualization. It contributes to the debates about the nature and focus of art in the digital era by assessing historical, economic and creative factors. It showcases how digital art might be understood as a particular medium, platform, network, aesthetic and function, and it also argues that digital art does not fit into those categories. Instead notions of transformation, scope and duration are used to account for new forms of artistic expression.
Topic Modeling in Russia: Current Approaches and Issues in Methodology
Authors: Bodrunova Svetlana S. 
Published: January 2021

AbstractTopic modeling as an instrument of probabilistic clustering for text collections has gained particular attention within the computational social science in Russia. This chapter looks at how topic modeling techniques have been developed and employed by the Russian scholars, both for Russian and other languages. We divide the works on topic modeling into methodological, applied, relational, and those dedicated to modeling quality assessment. While the methodological studies are the most developed, the works explaining the substance of the Russian-language discussions cover an important niche in political and social science. However, there is a gap between method-oriented works that treat Russian as “language as such” and the works by computational linguists who focus on Russian but treat topic modeling as a method of secondary importance.
Topic Modeling Russian History
Authors: Oiva Mila 
Published: January 2021

AbstractTopic modeling is a highly useful method that can provide new ways to understand the past. In order to reach the full potential of the method, the researcher needs to understand the context, the specifics of the data, and how the algorithm works and know the research literature. This chapter demonstrates how topic modeling can be applied in the studies of Russian and East European history. It illustrates the choices a researcher will face and the needed steps for preparing a data set for topic modeling, and shows how the interpretation of topic modeling results works in practice. The chapter also addresses the question of the scattered nature of digitized collections of Russian history sources, and the associated challenges and opportunities in this context.
Digital Journalism: Toward a Theory of Journalistic Practice in the Twenty-First Century
Authors: Strukov Vlad 
Published: January 2021

AbstractThe chapter explores transformations in journalism caused by the spread of digital technologies. These include collecting and displaying information, collaboration, carrying out journalistic investigation, entrepreneurship and regimes of exploitation. The chapter pays attention to the role of the government, private media companies, technology companies, cultural institutions and other organizations that advance and regulate journalistic work in Russia in new ways. It ultimately discusses new opportunities and new challenges available to journalists. The chapter conceptualizes digital journalism vis-à-vis alternative journalism and vis-à-vis grassroots journalism. In the final section of the chapter, I define digital journalism as a world-building process, thus contributing to theories of transmedia storytelling and cross-platform collaboration.
Balancing of Individual Rights and Research Interests in Danish Biobank Regulation
Authors: Hartlev Mette 
Published: January 2021

AbstractDenmark offers very good opportunities for biobank research. There is a vast number of well-structured and comprehensive collections of biological material, which in combination with a ‘research generous’ legislation provides an excellent environment for biobank research. However, both the Danish biobank landscape and the regulatory environment is rather complex. In contrast to a number of other countries, there is no specific biobank act in Denmark. Instead, various regulatory regimes interact, which makes it challenging to navigate in the legal landscape. It is also rather non-transparent for the individuals, from whom samples have been collected, what samples are used for, and how they can influence the use of samples for research. With the GDPR and the Danish Data Protection Act it seems that research participants’ rights have been slightly weakened in Danish law. However, it is argued, that the GDPR has the potential to ensure more awareness of research participants right against the societal and scientific interest in research.
Regulatory Environment for Biobanking in Estonia
Authors: Pormeister Kärt 
Published: January 2021

AbstractThe regulatory framework for biobanking in Estonia is fragmented. Whilst a specific law applies to the population-wide biobank, other entities engaged in biobanking are subject to rules stemming from various legal sources. In the case of the population biobank, participants give open consent for their data and tissue to be used in genetic research. Most other entities do not have the possibility to obtain open research consent for the use of personal data. However, national data protection law enables the use of personal data in research without the consent of individuals.In contrast, since no stricter requirements are set, open consent can be used when tissue is obtained directly from individuals for research purposes. However, if tissue is initially obtained for other (research) purposes, further research use requires written consent in the case of blood, while due notification will suffice for most other types of tissue.
Setting the Foundations: Individual Rights, Public Interest, Scientific Research and Biobanking
Authors: Slokenberga Santa 
Published: January 2021

AbstractThe principle of conferral tames the EU competence to regulate research in a comprehensive manner, yet furthering research is one of its aspirations. Data protection, however, is an area within which the EU has legislated extensively. During the development of the General Data Protection Regulation (GDPR), an important issue to tackle was how to balance the ambitious EU aspirations and differing stakeholder interests, on the one hand, with limited competences in research regulation, on the other, and how to determine the extent to which data protection could be used as a means to further scientific research in the EU legal order. The outcome is the GDPR multifaceted research regime that sets forth EU policy and opens up for further regulations from the Member States as well as the EU.The research regime that the GDPR has created poses numerous questions. Key among these is, what are the implications of the operationalisation of Article 89 GDPR in biobanking? This chapter sets out some of the underlying tensions in the area and pins down key conceptual foundations for the book. It provides insights into the EU’s interests in the area of biobanking and maps out central elements of the research regime that has been built within the GDPR. Thereafter, it analyses the key concepts used in the book, including biobank and biobanking, scientific research as undertaken under the GDPR, individual rights and public interest. Lastly, it shares some preliminary reflections as starting points for the analysis to come.
Swedish Law on Personal Data in Biobank Research: Permissible But Complex
Authors: Stenbeck Magnus , Fält Sonja Eaker , Reichel Jane 
Published: January 2021

AbstractThis chapter describes the regulatory and organisational infrastructure of biobank research in Sweden, and how the introduction of the GDPR affects the possibilities to use biobank material in future research. The Swedish legislator has chosen a rather minimalistic approach in relation to the research exception in Article 89 GDPR and has only enacted limited general exceptions to the data protection rules. This may be partly explained by the comprehensive right to public access to official documents which gives researchers vast access to information held in registries, albeit conditioned on abiding by secrecy and confidentiality rules. The Swedish legislation implementing the GDPR includes a general exception from the data protection rules in relation to the right to access to official documents, which researchers also benefit from. However, confidentiality rules for different categories of information differ between sectors, which hinders an effective use of the registries in research. The regulatory regime for using biobank and registry data in Sweden thus involves both data protection and secrecy rules, which makes the legal landscape permissible but complex. The operationalisation of the research exception in Article 89 GDPR is analysed against this background. Special attention is given to the possibility to link personal information derived from biobanks with personal information from other data sources, including large national population based statistical registries as well as information from national clinical registers.
Individual Rights in Biobank Research Under the GDPR
Authors: Staunton Ciara 
Published: January 2021

AbstractThe coming into force of the General Data Protection Regulation (GDPR) on 25 May 2018 has brought about considerable changes in how data may collected, stored and used. Biobanks, which require the collection, use and re-use of large quantities of biological samples and data, will be affected by the proposed changes. In seeking to require ‘data protection by design’, the GDPR provides data subjects with certain individual rights. They are, the right to be informed, the right of access, the right to rectification, the right to erasure, the right to restrict processing, the right to data portability, the right to object and rights in relation to automated decision making and profiling.This chapter will consider each of these individual rights in turn and discuss the impact on biobank research. In particular, it will discuss the challenges that are now facing biobanks in upholding the individual rights, the limits of these rights in light of the technical realities of biobanks, and the potential impact that they may have on the collection, sharing, use and re-use of biological data and material.
Digital Transformation in Learning Organizations
Authors: Helbig Christian , Hofhues Sandra , Egloffstein Marc , Ifenthaler Dirk 
Published: January 2021

AbstractThis concluding chapter takes a summarizing look at the contributions of the anthology, guided by two overarching questions: What dimensions are involved in the digital transformation of learning organizations? Which design perspectives can be used for digital transformation in learning organizations? In conclusion, this chapter leads back to the starting point of the anthology: the project #ko.vernetzt and the question of what significance the dimensions and design perspectives of digital transformation have in learning organizations.