bluuebunny/crossref_metadata_2025_split huggingface dataset:
A multi‐phase study for the development of a self‐efficacy measuring scale for ostomy care nursing management
Authors: Dellafiore Federica , Pittella Francesco , Arrigoni Cristina , Baroni Irene , Conte Gianluca , Di Pasquale Cristina , Casole Lorenzo , Villa Giulia , Caruso Rosario 
Published: October 2019

AbstractAimTo develop and psychometrically test a self‐efficacy scale for ostomy care nursing management.DesignThis study adopted a multi‐method and multi‐phase design.MethodPhase 1 of the study was comprised of the developmental tasks, where items were generated based on the emergent themes from literature. The items were then discussed with a panel of experts. Phase 2 focused on the validation process of the scale, where its content validity, construct and concurrent validity, and its internal consistency were assessed. The validation process was conducted between January 2018 ‐ January 2019.ResultsThe final version of the self‐efficacy scale in ostomy care nursing management encompasses 24 items in three domains, namely the clinical assessment domain, the education and relationship domain, and the teamwork domain. The scale showed the evidence of face and content validity, adequate construct and concurrent validity, and adequate internal consistency.ConclusionThe developed scale can be used in clinical and educational research.ImpactThis study presents the development and validation of the first valid and reliable self‐reporting measurement for nurses’ self‐efficacy in ostomy care nursing management. Self‐efficacy ostomy care nursing management encompasses 24 items and three domains, which are clinical assessment, education and relationship, and teamwork. This research will have an impact on nursing education, as it addresses the need for a specific self‐efficacy assessment of ostomy care nursing management. Self‐efficacy ostomy care nursing management will have an impact on nurses and patients, as it can be used to improve nurses’ self‐efficacy and clinical outcomes for patients in ostomy care.
Role of Post‐Acute Care in Readmissions for Preexisting Healthcare‐Associated Infections
Authors: Hoffman Geoffrey J. , Min Lillian C. , Liu Haiyin , Marciniak Dan J. , Mody Lona 
Published: October 2019

OBJECTIVESAlthough preventable, healthcare‐associated infections (HAIs) are commonly observed in post‐acute care settings for at‐risk older adults and are a leading cause of hospital readmissions. However, whether HAIs resulting in avoidable readmissions for preexisting HAIs (the same HAI as at the index admission) are more common for patients discharged to post‐acute care as opposed to home is unknown. We examined the risk of preexisting HAI readmissions according to patient discharge disposition and comorbidity level.DESIGNWe used 2013‐2014 national hospital discharge data to estimate the likelihood of readmissions for preexisting HAIs according to patients' discharge disposition and whether the likelihood varies according to patient comorbidity level, across four common types of HAIs (not including respiratory infections).PARTICIPANTSA total of 702 304 hospital discharges for Medicare beneficiaries 65 years or older.MEASUREMENTSOur outcome was a 30‐day preexisting, or “linked,” HAI readmission (readmission involving the same HAI diagnosis as at the index admission). Patient discharge disposition was skilled nursing facility (SNF), home health care, and home care without home health care (“home”).RESULTSOf 702 304 index admissions involving HAI treatment, 353 073 (50%) were discharged to a SNF, 179 490 (26%) to home health care, and 169 872 (24%) to home. Overall, 17 523 (2.5%) of preexisting HAIs resulted in linked HAI readmissions, which were more common for Clostridioides difficile infections (4.0%) and urinary tract infections (2.4%) than surgical site infections (1.1%; P < .001). Being discharged to a SNF compared to home or to home health care was associated with a 1.15 percentage point (95% confidence interval = −1.29 to −1.00), or 38%, lower risk of a linked HAI readmission. This risk difference was observed to increase with greater patient comorbidity.CONCLUSIONSSNF discharges were associated with fewer avoidable readmissions for preexisting HAIs compared with home discharges. Further research to identify modifiable mechanisms that improve posthospital infection care at home is needed. J Am Geriatr Soc 68:370–378, 2020
The Biogeographic Importance of Buoyancy in Macroalgae: A Case Study of the Southern Bull‐Kelp Genus Durvillaea (Phaeophyceae), Including Descriptions of Two New Species1
Authors: Fraser Ceridwen I. , Velásquez Marcel , Nelson Wendy A. , Macaya Erasmo C. , Hay Cameron H. 
Published: October 2019

Long‐distance dispersal plays a key role in evolution, facilitating allopatric divergence, range expansions, and species movement in response to environmental change. Even species that seem poorly suited to dispersal can sometimes travel long distances, for example via hitchhiking with other, more intrinsically dispersive species. In marine macroalgae, buoyancy can enable adults—and diverse hitchhikers—to drift long distances, but the evolution and role of this trait are poorly understood. The southern bull‐kelp genus Durvillaea includes several non‐buoyant and buoyant species, including some that have only recently been recognized. In revising the genus, we not only provide updated identification tools and describe two new species (D. incurvata comb. nov. from Chile and D. fenestrata sp. nov. from the Antipodes Islands), but also carry out biogeographic analyses to determine the evolutionary history of buoyancy in the genus. Although the ancestral state was resolved as non‐buoyant, the distribution of species suggests that this trait has been both gained and lost, possibly more than once. We conclude that although buoyancy is a trait that can be useful for dispersal (creating evolutionary pressure for its gain), there is also evolutionary pressure for its loss as it restricts species to narrow environmental ranges (i.e., shallow depths).
Convergent evolution of the UbiA prenyltransferase family underlies the independent acquisition of furanocoumarins in plants
Authors: Munakata Ryosuke , Kitajima Sakihito , Nuttens Andréïna , Tatsumi Kanade , Takemura Tomoya , Ichino Takuji , Galati Gianni , Vautrin Sonia , Bergès Hélène , Grosjean Jérémy , Bourgaud Frédéric , Sugiyama Akifumi , Hehn Alain , Yazaki Kazufumi 
Published: October 2019

Summary

Furanocoumarins (FCs) are plant‐specialized metabolites with potent allelochemical properties. The distribution of FCs is scattered with a chemotaxonomical tendency towards four distant families with highly similar FC pathways. The mechanism by which this pathway emerged and spread in plants has not been elucidated.

Furanocoumarin biosynthesis was investigated in Ficus carica (fig, Moraceae), focusing on the first committed reaction catalysed by an umbelliferone dimethylallyltransferase (UDT). Comparative RNA‐seq analysis among latexes of different fig organs led to the identification of a UDT. The phylogenetic relationship of this UDT to previously reported Apiaceae UDTs was evaluated.

The expression pattern of F. carica prenyltransferase 1 (FcPT1) was related to the FC contents in different latexes. Enzymatic characterization demonstrated that one of the main functions of FcPT1 is UDT activity. Phylogenetic analysis suggested that FcPT1 and Apiaceae UDTs are derived from distinct ancestors, although they both belong to the UbiA superfamily. These findings are supported by significant differences in the related gene structures.

This report describes the identification of FcPT1 involved in FC biosynthesis in fig and provides new insights into multiple origins of the FC pathway and, more broadly, into the adaptation of plants to their environments.
The effect of anthropogenic and environmental factors in coupled human‐natural systems: Evidence from Lake Zürich
Authors: Baggio Michele , Chavas Jean‐Paul , Di Falco Salvatore , Hertig Andreas , Pomati Francesco 
Published: October 2019

AbstractExploiting a rich data set including both individual fishing activities and ecology, we study how eutrophication and climate warming influence plankton biodiversity in Lake Zürich and the consequent effects on fishers’ behavior and fishery yield. Our analysis indicates that changes in the fishery of Lake Zürich were driven by complex dynamic interactions between fishing efforts, environmental conditions, and lake ecosystem ecology. Results show that nutrient levels and climate warming have both direct and indirect dynamic and nonlinear effects on both fishers’ behavior and lake productivity. Ecological factors such as plankton abundance and diversity affect the dynamics of the fish population, which, in turn, influences fishing effort. The analysis highlights the importance and the interdependence of ecological‐human linkages in aquatic ecosystems.Recommendations for Resource Managers

This model estimates and simulates the effects of temperature and nutrients on the ecology and the management of a commercial lake fishery.
Natural and anthropogenic factors have both direct and indirect effects on fishing intensity and the dynamics of lake productivity.
In the long term, increasing phosphorus has negative impacts on the plankton of the lake; higher nitrogen has a positive impact on zoo‐abundance, but a negative impact on zoo‐richness; higher temperatures have positive effects on phytoplankton.
Considerable heterogeneity exists in both in lake ecology at different habitats (top vs. bottom of the lake) and behavioral response (pelagic nets vs. demersal nets) to environmental fluctuations.
The neural substrates responsible for how trait anxiety affects delay discounting: Right hippocampal and cerebellar connectivity with bistable right inferior parietal lobule
Authors: Zhang Rong , Chen Zhiyi , Liu Peiwei , Feng Tingyong 
Published: October 2019

AbstractDelay discounting, an indicator of impulsivity, refers to the extent of devaluing future rewards. Studies have found that individuals with trait anxiety generally depreciate the later larger rewards, showing steeper delay discounting rates. However, little is known about the neural substrates responsible for how trait anxiety affects individuals' delay discounting. To address this question, we employed the voxel‐based morphometry (VBM) and resting‐state functional connectivity (RSFC) methods to explore the neural substrates of trait anxiety responsible for delay discounting. Behavioral results showed that trait anxiety was significantly positively correlated with delay discounting rates. The VBM analysis revealed that gray matter volumes of the right hippocampus (RHPC) and right cerebellum (RCere) were significantly positively correlated with trait anxiety. Moreover, the RSFC results showed that bistable right inferior parietal lobule (RIPL) connectivity with the RHPC and RCere were all inversely associated with trait anxiety. More importantly, mediation analysis indicated that trait anxiety played a completely mediating role in the relation between functional connectivity of RHPC‐RIPL and RCere‐RIPL and delay discounting. These results suggested that bistable RIPL connectivity with RHPC and RCere could be neural substrates underlying the effect of trait anxiety on delay discounting. On the whole, the current study yields insights into how trait anxiety affects delay discounting and provides a novel account from a neural basis perspective.
Aggression in toddlerhood: The roles of parental beliefs, parenting behavior and precursors of theory of mind
Authors: van Adrichem Dide S. , Huijbregts Stephan C. J. , van der Heijden Kristiaan B. , van Goozen Stephanie H. M. , Swaab Hanna 
Published: October 2019

AbstractParental beliefs, parenting behavior, and precursors of theory of mind have been related uniquely to each other and to early aggression, but have not yet been studied simultaneously. The present study combined these risk factors in the prediction of aggression during toddlerhood using a sample of 152 mother–child dyads. At 20 months, mothers' parental beliefs (parental self‐efficacy and perceived parental impact) were examined with the Parental Cognitions and Conduct Toward the Infant Scale. Maternal parenting behavior (sensitivity, intrusiveness, and successful positive engagement) was observed during free play and teaching tasks, and children's precursors of theory of mind were assessed using a visual perspectives task and an imitation task. At 30 months, child aggression was examined using the Child Behavior Checklist. A regression analysis indicated that lower parental self‐efficacy and lower imitation skills predicted more aggressive behavior. When estimating the indirect effects using bootstrapping, a final model was found indicating that lower perceived parental impact was related to less successful positive engagement, which, in turn, was associated with children's poorer imitation abilities which predicted more aggressive behavior. It can be concluded that aggression during toddlerhood is predicted significantly by interrelated parental beliefs, parenting behavior, and children's early social cognitive abilities.
Transfer of Hexon‐ and Penton‐selected adenovirus‐specific T cells for refractory adenovirus infection after haploidentical stem cell transplantation
Authors: Schultze‐Florey Rebecca E. , Tischer‐Zimmermann Sabine , Heuft Hans‐Gert , Priesner Christoph , Lamottke Britta , Heim Albert , Sauer Martin , Sykora Karl‐Walter , Blasczyk Rainer , Eiz‐Vesper Britta , Maecker‐Kolhoff Britta 
Published: October 2019

AbstractAdenovirus (HAdV) infections confer a high risk of morbidity and mortality for immunocompromised patients after stem cell transplantation (SCT). Treatment with standard antiviral drugs is of limited efficacy and associated with a high rate of adverse effects. HAdV‐specific T cells are crucial for sustained viral elimination and the efficacy of adoptive T‐cell therapy with donor‐derived HAdV‐specific T cells has been reported by several investigators. Here, we report our experience with the transfer of HAdV‐specific T cells specific for penton, which was recently identified as an immunodominant target of T cells, and hexon in a 14‐year‐old boy after T‐cell‐depleted haploidentical SCT for myelodysplastic syndrome (MDS). He developed severe HAdV‐associated enteritis complicated by acute graft‐versus‐host disease (GvHD). The patient received ten infusions of allogeneic HAdV‐specific T cells manufactured from the haploidentical stem cell donor using the CliniMacs Interferon‐γ (IFN‐γ) cytokine capture and immunomagnetic selection. Initially, T cells were generated against the immunodominant target hexon and in subsequent transfers dual antigen‐specific T cells against hexon and penton were applied. T‐cell transfers were scheduled individually tailored to current immunosuppressive treatment. Each transfer was followed by reduction of HAdV load in peripheral blood and clinical improvement. Importantly, T‐cell responses to both penton and hexon pools emerged in patient blood after repetitive transfers. Unfortunately, the patient experienced bacterial sepsis, and in this context, severe GvHD requiring intensive immunosuppression followed by secondary progression of HAdV infection. The patient succumbed to multiorgan failure 283 days after SCT. This case demonstrates the feasibility of HAdV‐specific T‐cell transfer even in the presence of immunosuppressive treatment. Targeting of multiple immunodominant viral proteins may prove valuable in patients with complicated HAdV infections.
Erreurs fossilisables de prononciation du français chez des apprenants hispanophones
Authors: Deswarte Chloé , Baquero Fanny Janneth , Reyes-Rincón Javier Hernando , Plata-Peñafort Carolina 
Published: October 2019

L'article présente les erreurs fossilisables que les étudiants de Licence en Langues Modernes de l'Université Pontificale Javeriana commettent en phonétique et phonologie dans les niveaux intermédiaires (B2) de français.
À partir des concepts clés (phonétique, phonologie, fossilisation et erreur fossilisable), nous analyserons un corpus de productions orales, les réponses à un questionnaire adressé aux étudiants et des entretiens semi-directifs réalisés aux professeurs des cours.
Nous démontrons que les erreurs caractéristiques des hispanophones persistent dans ces niveaux et risqueraient de ne pas être corrigées à moins que des stratégies pédagogiques soient mises en place à fin d'empêcher leur fossilisation.
Diagnosis and treatment of peripheral exudative haemorrhagic chorioretinopathy
Authors: Vandefonteyne Sarah , Caujolle Jean-Pierre , Rosier Laurence , Conrath John , Quentel Gabriel , Tadayoni Ramin , Maschi Celia , Le Mer Yannick , Dot Corinne , Aknin Isabelle , Thariat Juliette , Baillif Stephanie 
Published: October 2019

PurposePeripheral exudative haemorrhagic chorioretinopathy (PEHCR) is a rare disorder that is often misdiagnosed. The aim of this study was to better characterise PEHCR and to assess treatment options.Material and methodsRetrospective multicentric chart review.ResultsOf 84 eyes (69 patients) with PEHCR referred between 2005 and 2017, the most common referral diagnosis was choroidal melanoma (41.3%). Bilateral involvement was found in 21.7% of cases. Haemorrhagic retinal pigment epithelium detachment was the most common peripheral lesion (53.6%). Maculopathy was associated with peripheral lesions in 65.8% of cases. PEHCR lesions were mostly heterogeneous (58.8%) on B-scan ultrasonography. Choroidal neovascularisation was found in 10 eyes (26.3%) out of 38 eyes that underwent fluorescein angiography. Polyps were observed in 14 eyes (58.3%) out of 24 eyes that underwent indocyanine green angiography. Fifty-one eyes were treated (62.2%). Intravitreal injections (IVTI) of antivascular endothelial growth factor (VEGF) were the most used treatment (36.6%) before laser photocoagulation, photodynamic therapy, vitrectomy and cryotherapy. Only vitrectomy improved visual acuity. Most lesions (65.6%) regressed at the last follow-up visit.ConclusionIn case of PEHCR, multimodal imaging is useful to avoid misdiagnosis, to characterise PEHCR lesions and to guide treatment strategies. Regression of PEHCR lesions was observed in two-thirds of the patients. Vitrectomy improved visual acuity. More than a third of patients underwent anti-VEGF IVTI. Further studies are needed to assess IVTI’s efficacy.
Outcomes in children evaluated but not transported by ambulance personnel: retrospective cohort study
Authors: Oulasvirta Jelena , Salmi Heli , Kuisma Markku , Rahiala Eero , Lääperi Mitja , Harve-Rytsälä Heini 
Published: October 2019

BackgroundNot all children with an out-of-hospital emergency medical contact are transported by ambulance to the emergency department (ED). Non-transport means that after on-scene evaluation and possible treatment, ambulance personnel may advise the patient to monitor the situation at home or may refer the patient to seek medical attention by other means of transport. As selecting the right patients for ambulance transport is critical for optimising patient safety and resource use, we studied outcomes in non-transported children to identify possible risk groups that could benefit from ambulance transport.MethodsIn a population-based retrospective cohort study of all children aged 0–15 years encountered but not transported by ambulance in Helsinki, Finland, between 1 January 2014 and 31 December 2016, we evaluated (1) 12-month mortality, (2) intensive care admissions, (3) unscheduled ED contacts within the following 96 hours after the non-transport decision and (4) the clinical status of the child on presentation to ED in the case of a secondary ED visit.ResultsOf all children encountered by out-of-hospital emergency medical services, 3579/7765 (46%) were not transported to ED by ambulance. There was no mortality or intensive care admissions related to the non-transport. The risk factors for an unscheduled secondary ED visit after a non-transport decision were young age (p=0.001), non-transport decision during the early morning hours (p<0.001) and certain dispatch codes, including ‘dyspnoea’ (p<0.001), ‘vomiting/diarrhoea’ (p=0.030) and ‘mental illness’ (p=0.019). We did not detect deterioration in patients’ clinical presentation at ED traceable to non-transport decisions.ConclusionsNot transporting all children by ambulance after an out-of-hospital emergency medical contact was not associated with deaths, intensive care admissions or significant deterioration in general condition in our study population and healthcare system. Special attention and a formal non-transport protocol are warranted in certain subgroups, including infants.
Principal component analysis of collective flow in relativistic heavy-ion collisions
Authors: Liu Ziming , Zhao Wenbin , Song Huichao 
Published: October 2019

Abstract
In this paper, we implement principal component analysis (PCA) to study the single particle distributions generated from thousands of $$\mathtt {VISH2+1}$$VISH2+1 hydrodynamic simulations with an aim to explore if a machine could directly discover flow from the huge amount of data without explicit instructions from human-beings. We found that the obtained PCA eigenvectors are similar to but not identical with the traditional Fourier bases. Correspondingly, the PCA defined flow harmonics $$v_n^\prime $$vn′ are also similar to the traditional $$v_n$$vn for $$n=2$$n=2 and 3, but largely deviated from the Fourier ones for $$n\ge 4$$n≥4. A further study on the symmetric cumulants and the Pearson coefficients indicates that mode-coupling effects are reduced for these flow harmonics defined by PCA.
High latitude meteoric
δ
18
O compositions from the Cenomanian Bastion Ridge Formation, Axel Heiberg Island, Canadian Arctic Archipelago: a palaeoclimate proxy from the Sverdrup Basin
Authors: Ross Jeffrey B. , Ludvigson G. A. , Schröder-Adams C. J. , Suarez M. B. 
Published: October 2019

Abstract

Stable isotope analyses of a siderite-cemented siltstone from the Cenomanian Bastion Ridge Formation, Axel Heiberg Island, Canada, produce a range of
δ
18
O values from −21.9 to −18.4‰ Vienna Pee Dee Belemnite (VPDB), and
δ
13
C values ranging from 2.0 to 4.4‰ VPDB. A meteoric siderite line of −18.95 ± 0.33‰ VPDB is calculated from siderite cements of the authigenic component. At estimated palaeolatitude of 68–72° N and palaeotemperature range from 12.6 to 13.7°C, the calculated
δ
18
O range of palaeoprecipitation is −23.3 to −23.0‰ Vienna Standard Mean Ocean Water (VSMOW). This result is compatible with other published meteoric water
δ
18
O datasets from Cretaceous Arctic studies, but is near the lower end of the range of estimated
δ
18
O values. The modern
δ
18
O empirical relationship of Dansgaard and Earth System models simulating meteoric
δ
18
O values does not yield results for palaeopolar regions that match proxy
δ
18
O datasets. Orographic effects of contemporaneous mountain belts and seasonal biases in groundwater recharge have been proposed to explain this paradox regarding depleted meteoric water
δ
18
O values from proxy data in greenhouse worlds. Evidence for local to regional orographic effects and alpine snowmelt biasing groundwater recharge is lacking for the Sverdrup Basin deposits, further indicating that the Dansgaard relationship does not apply to ancient greenhouse worlds.