bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Case of Neurosarcoidosis Mimicking Brain Tumor
Authors: Sari Lutfullah , Peker Abdusselim A. , Cesme Dilek H. , Alkan Alpay 
Published: November 2020

Background:
Neurosarcoidosis manifests symptomatically in 5% of patients with sarcoidosis
and diagnosis can be challenging if not clinically suspected. Cerebral mass-like presentation
of neurosarcoidosis rarely reported in the literature. We presented a woman with neurosarcoidosis
who had a cerebral mass-like lesion which completely disappeared after medical treatment.

Discussion:
A 37-year-old woman with history of pulmonary sarcoidosis referred to the emergency
service of our hospital with a one-month history of progressive dizziness, nausea and seeing
flashing lights. At neurologic examination, numbness and weakness on the left side of the body, deviation
of uvula toward the right side was seen. Cranial MRI demonstrated a 2.5x2 cm in size mass
lesion which hypointense on T1 WI, heterogeneous hyperintense on T2 and FLAIR sequence with
peripheral vasogenic edema and heterogeneous, irregular contrast enhancement simulating brain tumor.
Also, leptomeningeal and nodular contrast enhancement was seen on brainstem, cerebellar
vermis, perimesencephalic cistern and left frontal, bilateral parietooccipital sulcus. In laboratory
tests; The level of serum angiotensin-converting enzyme (ACE) was 53 IU/mL (N:8-52 IU/mL)
and cerebrospinal fluid (CSF) ACE was 23 IU/mL (N:0-2.6 IU/mL). CSF cytology analysis was
normal. Pattern 2 oligoclonal bands were present. With these clinical, laboratory and radiological
findings, cerebral involvement of sarcoidosis was suspected. Biopsy was not performed due to the
high risk of morbidity caused by the deep location of the lesion.Patient was treated with methylprednisolone
and Azathioprine for a month.On post-treatment control imaging; lesion disappeared
completely without residual leptomeningeal and nodular contrast enhancement.Also, neurologic
symptoms were decreased remarkably.

Conclusion:
Multi-system inflammatory disorders like sarcoidosis, can present with mass-like lesion
in the brain parenchyma. While early diagnosis is important to prevent unnecessary interventions
like biopsy and surgery, it is crucial to initiate the necessary treatment with the aim of recovery
without sequelae. Radiological and clinical follow-up are fundamental in differential diagnosis.
Denoising Medical Images Using Machine Learning, Deep Learning Approaches: A Survey
Authors: Arshaghi Ali , Ashourian Mohsen , Ghabeli Leila 
Published: November 2020

Objective:
Several de-noising methods for medical images have been applied such as Wavelet Transform,
CNN, linear and Non-linear method.

Methods:
In this paper, a median filter algorithm will be modified and explain the image de-noising to wavelet transform
and Non-local means (NLM), deep convolutional neural network (DnCNN) and Gaussian noise and Salt and pepper noise
used in the medical skin image.

Results:
PSNR values of CNN methods is higher and better than to others filters (Adaptive Wiener filter, Median filter
and Adaptive Median filter, Wiener filter).

Conclusion:
Denoising methods performance with indices SSIM, PSNR, and MSE have been tested,
and the results of simulation image denoising are also presented in this article.
Frequency of Pathological Types of Hyperthyroidism in Thyroid Scan Patients
Authors: Pooria Ali , Pourya Afsoun , Gheini Alireza 
Published: November 2020

Background:
Hyperthyroidism is a common systemic disorder where Graves’ disease is known as the leading
cause of the disease. Thyroid stimulating hormone, T4 and T3 antibody assay are usually performed for the diagnosis of
the pathology. However, with uncertainty in the results and in order to estimate the magnitude and the exact cause of the
disease, radioactive iodine uptake (RAIU) test is recommended. The aim of this study is to evaluate underlying pathology
in the patients presenting hyperthyroidism using RAIU test results.

Methods:
This is a cross-sectional retrospective study conducted on the patients with hyperthyroidism referred to Shahid
Madani Hospital in Khorramabad. Data regarding the biochemical analysis and RAIU test was collected from the records
and a questionnaire based on demographic and clinical information was completed for each patient.

Results:
Of 137 patients presenting hyperthyroidism, 62.04% were presented with Graves’ disease, 24.08% with toxic
multinodular goiter and 13.86% with toxic adenoma. 24-hour RAIU test showed that the percent of radioiodine uptake
was most in toxic adenoma 67.7%, Graves’ disease 53.5% and multinodular goiter 39%, respectively. From the age-based
analysis, we found that Graves’ was most common in 20-30 years old individuals 34%, multinodular goiter in 50+ aged
individuals 36.3% and toxic adenoma was most prevalent in 30-40 and 50+ aged patients, 26.3% each. In our population
of interest, 81.8% toxic multinodular goiter patients were females.

Conclusions:
Our study presents the outcome of RAIU tests in hyperthyroidism based on the underlying pathologies. We
also conclude, in light of other findings, Graves’ disease is the most common cause of hyperthyroidism in our population.
A Perspective on Client-Psychologist Relationships in Videoconferencing Psychotherapy: Literature Review
Authors: Cataldo Francesco , Chang Shanton , Mendoza Antonette , Buchanan George 
Published: November 2020

BackgroundDuring the COVID-19 pandemic, people have been encouraged to maintain social distance. Technology helps people schedule meetings as remote videoconferencing sessions rather than face-to-face interactions. Psychologists are in high demand because of an increase in stress as a result of COVID-19, and videoconferencing provides an opportunity for mental health clinicians to treat current and new referrals. However, shifting treatment from face-to-face to videoconferencing is not simple: both psychologists and clients miss in-person information cues, including body language.ObjectiveThis review proposes a new theoretical framework to guide the design of future studies examining the impact of a computer as a mediator of psychologist-client relationships and the influence of videoconferencing on the relationship process.MethodsWe conducted a literature review including studies focused on communication and key concepts of the therapeutic relationship and therapeutic alliance.ResultsStudies have reported that clients are generally satisfied with videoconference therapy in terms of the relationship with their therapists and the establishment of the therapeutic alliance. Conversely, studies indicate that psychologists continue to highlight difficulties in establishing the same quality of therapeutic relationship and therapeutic alliance. The contrasting experiences might underlie the differences in the type of emotional and cognitive work required by both actors in any therapy session; furthermore, the computer seems to take part in their interaction not only as a vehicle to transmit messages but also as an active part of the communication. A new model of interaction and relationship is proposed, taking into account the presence of the computer, along with further hypotheses.ConclusionsIt is important to consider the computer as having an active role in the client-psychologist relationship; thus, it is a third party to the communication that either assists or interferes with the interaction between psychologists and clients.
Mobile App-Based Intervention for Pregnant Women With Stress Urinary Incontinence: Protocol for a Hybrid Effectiveness-Implementation Trial
Authors: Li Tiantian , Chen Xiaomin , Wang Jia , Chen Ling , Cai Wenzhi 
Published: November 2020

Background
Stress urinary incontinence (SUI) is a common source of distress among women during and after pregnancy. It has a negative effect on quality of life but with poor care-seeking. Mobile health (mHealth) may be a promising solution with potential advantages. However, there is uncertainty whether a mobile app is effective for SUI symptom improvement during and after pregnancy. The implementation is also unclear. We developed an app named UIW (Urinary Incontinence for Women) aimed at improving perinatal incontinence.

Objective
The objective of this study is to evaluate the effectiveness of the UIW app-based intervention in improving SUI symptoms among pregnant women and explore the facilitators and barriers to using the UIW app to help refine and optimize the intervention.

Methods
This study is a hybrid effectiveness-implementation trial with a randomized controlled trial alongside a mixed-methods process evaluation according to the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. Pregnant women with SUI (n=336) will be recruited from a university-affiliated hospital in China. They will be randomly allocated (1:1) to either the intervention group that receive usual care plus UIW app or control group that receive usual care alone. The intervention period will last 2 months. The 5 dimensions of the RE-AIM framework will be evaluated at recruitment (-T1), baseline (T0), immediately after intervention (T1), 42 days after delivery (T2), 3 months after delivery (T3), and 6 months after delivery (T4) through project documents, online questionnaires and a pelvic floor muscle training diary, surface electromyography, log data in the background management system, and qualitative interviews. Data analysis will follow the intention-to-treat principle. Descriptive statistics, t tests, chi-square tests, and a linear mixed model will be used to analyze the quantitative data. Deductive and inductive content analysis will be used to analyze the qualitative data.

Results
The effectiveness-implementation trial started in June 2020, trial recruitment was completed in October 2020, and the intervention will last for a 2-month period. Completion of the 6-month follow-up will be in July 2021, and we anticipate that the results of this study will be published in December 2021.

Conclusions
This study will evaluate both effectiveness and implementation of the UIW app-based intervention among pregnant women. The hybrid effectiveness-implementation trial design according to the RE-AIM framework with a mixed-methods approach will give valuable insights into the effects as well as facilitators and barriers to the implementation that will influence the effects of the UIW app-based intervention.

Trial Registration
Chinese Clinical Trial Registry ChiCTR1800016171; http://www.chictr.org.cn/showproj.aspx?proj=27455

International Registered Report Identifier (IRRID)
PRR1-10.2196/22771
Integrated Digital Patient Education at the Bedside for Patients with Chronic Conditions: Observational Study
Authors: Schooley Benjamin , Singh Akanksha , Hikmet Neşet , Brookshire Robert , Patel Nitin 
Published: November 2020

Background
Patient education delivered by a health care provider increases patients’ understanding and adherence to medical instructions, which helps to improve patient health. Multiple challenges exist to delivering effective patient education to patients with multiple chronic conditions, including giving the necessary time, range, and types of learning materials, and assessing the level of understanding. To help overcome these challenges, it is important to study new electronic means to assist in patient education, such as the use of mobile devices, interactive media, 3-dimensional images, and multimedia educational content at the bedside.

Objective
The goal of this study was to address the need for blended learning strategies combining technical and workflow integration of digital patient education systems for patients with chronic conditions within and across the regular process of care. Studies are needed to evaluate the utility and benefits of these technologies for providers and patients alike.

Methods
A mixed-methods approach was employed including survey administration to 178 patients after they received digital patient education in person with a health care provider, and qualitative interviews with 16 nurse educators who used the mobile digital health education technology to deliver instruction to patients. Patient survey data were analyzed using chi-square statistical tests. Qualitative interviews were analyzed for user acceptance and perceived value themes.

Results
Patients who were counseled using a blended digital health education approach reported improved understanding of educational content (P=.034) and chronic health conditions (P<.001), were more motivated to care for themselves at home (P<.001), were more likely to say that they felt capable of making health care decisions with their doctors (P<.001) and on their own (P=.001), and were more likely to report their intention to follow their doctor’s instructions (P<.001) than were patients whose education was not computer-based. Nurse educators felt that the digital education system and content enhanced their education efforts and could be easily integrated into the outpatient clinical workflow.

Conclusions
Patient education for individuals with chronic conditions may be more effective than traditional formats when provided in blended digital formats supervised by a health care provider.
Los parámetros magnéticos como indicadores de contaminación por elementos mayores y plomo en suelos urbanos del Valle de Aburrá, Colombia
Authors: Sánchez-Duque Alexander , Bautista Francisco , Cejudo Rubén , Goguitchaichvili Avto , Cervantes-Solano Miguel 
Published: November 2020

Presentamos un estudio de magnetismo ambiental con el objetivo de determinar la relación entre metales pesados y los parámetros magnéticos en suelos urbano del Área Metropolitana de Valle de Aburrá (AMVA), Colombia, con la finalidad de establecer indicadores magnéticos que permitan estimar la concentración de minerales magnéticos, elementos mayores, concentración de Pb y sus áreas de mayor acumulación en la zona urbana del Área Metropolitana del Valle de Aburrá AMVA (Colombia). El estudio se realizó a partir de 83 muestras de suelo urbano, las cuales fueron sujetas a un análisis magnético, se determinó la concentración de los elementos mayores (Al2O3, Fe2O3 y MnO) y concentración de Pb por medio de fluorescencia de Rayos X de energía dispersa. Se encontró una variación en la distribución del material magnético en el suelo urbano, el cual contiene una mezcla de minerales magnéticos de baja coercitividad o magnetita de origen natural y antrópico. Se detectaron partículas de tamaño superparamagnético en concentraciones medias y bajas en los suelos de baja actividad antrópica lo que sugiere un origen natural. Por otra parte, mediante la combinación de los parámetros magnéticos y a partir de curvas termomagnéticas se encontraron suelos con concentración alta de mineral magnético de origen antrópico. Las concentraciones de Al2O3 y Fe2O3 son altas y similares en la mayor parte de los suelos urbanos en comparación del contenido de MnO. Los usos de suelo que mostraron baja actividad antrópica presentaron un contenido bajo de Pb, mientras que, para los usos de suelo con mayor carga antrópica, se observó que la concentración de Pb se incrementa.
El suelo de los espacios públicos con baja actividad antrópica fue empleado para determinar el valor de referencia para cada elemento y parámetro magnético. El análisis estadístico mostró que, los suelos de AMVA tienen una relación directamente proporcional entre el material magnético y el contenido de Pb e inversamente proporcional con el contenido de Al2O3, Fe2O3 y MnO. Se estableció que el modelo matemático que predice la concentración de elementos a partir de parámetros magnéticos tiene una eficacia de 62 % y que el área que ocupan las zonas de acumulación de material magnético y contenido de Pb es de alrededor de 46 km2, lo cual representa el 25 % de la zona urbana y que es el área probable de riesgo por acumulación de material contaminante.
K.P. Pobedonostsev and V.V. Rozanov: “Fathers and Sons” of Russian Conservatism
Authors: Polunov Alexander Yu. 
Published: November 2020

The article is devoted to the analysis of the relations of two major representatives of Russian conservatism of the 19th–20th centuries, – the Ober-Procurator of the Most Hole Synod K.P. Pobedonostsev and publicist V.V. Rozanov. According to the author of the article, those relations revealed not just the personal specifics of both conservatives who initially sympathized with each other both personally and conceptually, but more the principle separation in the conservative camp that happened at the turn of the 19th and 20th centuries. It reflected both the generational and ideological contradictions in the views. In particular, the young conservatives of the turn of the century challenged the “protective” position of K.P Pobedonostsev demanding more efficient activity of the Church and the State in defending the basics of the existing order. Ideologically the new generation of conservatives believed that under the conditions of the ideological struggle aggravations at the turn of the century the conservative fundamentals need to be more clearly formulated and substantiated, while the Ober-Procurator definitely opposed such steps. In the long run those contradictions resulted in tragic consequences for both the conservatism as social and political trend in Russia, and for the destiny of Russian state system in the 20th century.
V.V. Rozanov on the Determinants and Specifics of Russian Consciousness (Relevance in the Context of the Problem of Echoing Epochs)
Authors: Tyapin Igor N. 
Published: November 2020

The article reconstructs V.V. Rozanov’s concepts of the essential characteristics of the Russian individual and social consciousness based on analytical review of the problems of foreign influence, and opposition to appearances and materialities, national civil infantilism and others in his works of various years. Conclusions are made on V.V. Rozanov’s methodology as the combination of idealistic and naturalistic approaches and reliance on the concept of the various trends of “Russian Idea” philosophy, on the gradual strengthening of his ideas on the evolution of Russian consciousness as the degradation of the family-patriotic-religious feeling, not based on the mind.
Sura: Ethnographer’s Views
Authors: Tutorsky Andrey V. 
Published: November 2020

The article gives a concise ethnographic characteristic of Sura village and its surroundings. The first part of the article is devoted to the issue of passageways in the vicinity of the village. The author utilizes M.V. Vitov’s approach to the problem of river traffic in the North. Furthermore, the reindeer-raising passageways are shown and the connection of those passageways with the Chuprov Bor landmark, on the Pinega side opposite to Sura, is described. The second part of the article offers a concise characteristic of two rituals: wedding ritual and “metishche” (specially selected place for festivals). The wedding ritual differs substantially from the Pinezh urban wedding ritual. The “Metishche” ritual on St. Peter’s Day is characterized on the basis of the literary description by S.G. Pisakhov. The third part of the article is devoted to the description of the events of 1920–1930 in Sura on the basis of the memories of L.A. Kychina (Malkina). Such issues as pre-kolkhoz life, collectivization and stratification in kolkhoz are touched upon.
“The Actual Population of Kiev… Stays Neutral”: Russian Monarchists and Bolshevistic-Ukrainian Confrontation (January of 1918)
Authors: Chemakin Anton A. 
Published: November 2020

The article is devoted to the viewpoint of Russian monarchists in Kiev who were caught in the crossfire of the Ukrainians and the Bolsheviks fighting with each other. One of the leaders of the “Russian Party” in Kiev V.V. Shulgin tried to enter into a tactical alliance with the Ukrainians in the person of S.V. Petliura in order to resist the advancing Bolshevist forces, but the negotiations collapsed. In the long run the main structures of the Russian movement, as well as the majority of the Russians in Kiev did not participate in the conflict of the Ukrainians and the Bolsheviks. And though the myth of the Black Hundreders participating in the Bolshevistic uprising at “Arsenal” plant was not confirmed, a certain part of the former members of workers’ monarchist unions most probably joined the rebels. The author comes to the conclusion that in the beginning of 1918 in Kiev the political groups that later confronted each other in the Civil War, were not finally formed, so there occurred certain tactical unions that were hardly imaginable in the later years.
Historiosophy of N.E. Markov: the Biblical Foundations and Conceptual Discoveries
Authors: Darenskiy Vitaliy Yu. 
Published: November 2020

The article examines the historiosophy of N.E. Markov (1866–1945) in the context of its biblical foundations and its conceptual discoveries, that allow us to reveal the “mechanisms” of the revolutions organization and Christian civilization destruction. It is shown that the return to the biblical and patristic understanding of history makes it possible to conceptualize the main spiritual forces of the world-historical process. The “mechanism” of revolutions organizing consists in creating organizational structures that are parallel to the state structures and are capable of paralyzing their functioning at the proper moment. The basis of the “dark forces” activity in history lies first in the elite consciousness manipulation and then – in the broad masses of population consciousness manipulation, which destroys the Christian worldview. According to N.E. Markov, the revival of Russia is possible only within the framework of real monarchy, since all other forms of government are manipulative forms of the “dark forces” dictatorship.
Embolization of the Renal Artery in Combined Treatment of Stage IV Kidney Cancer
Authors: Gantsev Sh. Kh. , Yun V. , Zhumagulova A. K. , Arybzhanov D. T. , Tursumetov D. S. 
Published: November 2020

Introduction. Kidney cancer remains an urgent problem in modern oncology. More than 200 thousand new cases of kidney cancer are diagnosed globally every year, with about 100 thousand patients dying. 15–17% of patients are diagnosed with stage IV kidney cancer. Arterial tumour embolization and nephrectomy are used as a palliative treatment.Aim. To evaluate the results of renal artery embolization in combined treatment of stage IV kidney cancer.Material and methods. The treatment results of 22 patients with stage IV kidney cancer are presented: 6 patients had metastases in the skeletal bones; 15 — metastases in the lungs; 1 — bilateral kidney damage. At the first stage, all patients underwent renal artery embolization. Subsequently, 6 patients received bisphosphonates and radiation therapy for metastases in the skeletal bones, 15 patients underwent operation followed by a targeted therapy with Sunitinib and Sorafenib), 1 patient with bilateral kidney damage underwent operation followed by a 2-year targeted therapy with Sorafenib.Results and discussion. Renal artery embolization was performed successfully without technical difficulties in all the patients. After embolization, hemostasis was achieved in all patients with hematuria (n = 14). Postembolization syndrome was noted in 13 patients with total renal artery embolization. 6 patients with metastases in the skeletal bones lived for 16.4 ± 2.1 months, the survival time of 15 patients who received renal artery embolization, nephrectomy and targeted therapy was 41.7 ± 15.3 months. Only one patient (bilateral kidney damage) has been under dynamic observation for the period of 10 years.Conclusion. Renal artery embolization is an effective and minimally invasive technical procedure that should be used in the combined treatment of patients with kidney cancer. The combined use of renal artery embolization and subsequent targeted therapy for kidney cancer provide new opportunities for stage IV combined treatment.