bluuebunny/crossref_metadata_2025_split huggingface dataset:
CÂNCER DE BOCA: AVALIAÇÃO DO CONHECIMENTO DE CIRURGIÕES-DENTISTAS DA ESTRATÉGIA DE SAÚDE DA FAMÍLIA DE MOSSORÓ (RN)
Authors: Samara Raquel Sousa de Oliveira  , Amanda Katarinny Goes Gonzaga  
Published: October 2020

Introdução: O câncer de boca é uma neoplasia maligna que representa um sério problema de saúde pública devido à alta incidência, prevalência e mortalidade e o cirurgião-dentista deve estar apto a diagnosticar essa doença. Objetivo: O presente estudo visou avaliar o conhecimento dos cirurgiões-dentistas da Estratégia de Saúde da Família de Mossoró (RN) sobre o câncer bucal. Metodologia: Para a coleta de dados, o pesquisador se deslocou à Unidade Básica de Saúde para convidar o profissional a participar da pesquisa e aplicou um questionário estruturado. Após a análise dos questionários, foi atribuído um conceito a cada entrevistado para avaliação do seu conhecimento sobre o câncer de boca. Para tabulação e análise dos dados, foi utilizado o programa estatístico Statiscal Package Social Sciences (SPSS) versão 23.0. Resultados: Em relação a autoavaliação, apenas 7% da amostra considerou-se com nível ótimo de conhecimento sobre a doença. Uma minoria (4,7%) participou de cursos com essa temática no ano passado. Observou-se, ainda, que 81,4% dos cirurgiões-dentistas apresentaram baixo nível de confiança para realizar procedimentos de diagnóstico do câncer bucal. Ao atribuir conceitos de acordo com as respostas dadas pelos profissionais sobre o conhecimento do câncer bucal, constatou-se que a maior parte dos cirurgiões-dentistas entrevistados obtiveram conceito regular (C) e bom (B) sobre o câncer de boca. Conclusões: A maior parte dos cirurgiões-dentistas de Mossoró apresentaram conhecimento entre regular e bom sobre o câncer de boca, entretanto uma parcela expressiva se autodeclara insegura para realizar o diagnóstico, sendo necessários treinamentos sobre o câncer de boca e atualizações que também contribuam com a elevação da autoconfiança desses profissionais.
HÁBITOS DE COMPRA E CONSUMO DE ALIMENTOS EM FAMÍLIAS COM MENORES DE CINCO ANOS EM UM MUNICÍPIO DO NORDESTE BRASILEIRO
Authors: Cristina Batista Costa Amanda , Silva Bezerra Mariana , Dantas Pinheiro Dandara , Rejane Siqueira Garcia Lígia , Cristini Martin Sousa Layanne , Araújo de Goes Pryscila 
Published: October 2020

Introdução: O ambiente alimentar pode influenciar nas decisões sobre os hábitos e modificar a aquisição e consumo de alimentos ao considerar que as escolhas alimentares são determinadas pelo acesso, disponibilidade, propaganda, conveniência e preço. Isso pode ocasionar consideráveis transformações no comportamento alimentar desde a infância. Objetivo: Avaliar os hábitos de compra e de consumo de alimentos em famílias com crianças menores de cinco anos em um município do Nordeste Brasileiro. Metodologia: Trata-se de uma pesquisa transversal, de abordagem quantitativa, realizada com 138 indivíduos nas seis unidades básicas de saúde urbanas do município. Foi realizada entrevista estruturada com aplicação de questionários sobre informações socioeconômicas, hábitos de compra e consumo de alimentos, segurança alimentar, peso e altura auto referidos. Os dados foram analisados no software Statistical Package for the Social Science Statistics (SPSS) versão 23.0. Foi realizado teste de associação entre os hábitos de compra e consumo de alimentos com dados socioeconômicos, estado nutricional antropométrico e segurança alimentar. Resultados: Dentre os hábitos de consumo avaliado, foi verificado que o consumo de salada crua (83,8%), frutas (95,9%) e suco de fruta ou de polpa (93,8%) em pelo menos um dia na semana, foram associados a uma maior escolaridade. Enquanto que a maior frequência de compra e consumo em restaurantes e lanchonetes foi associada a uma maior renda, possuir emprego e não participar de programas sociais. Conclusão: Hábitos de compra e de consumo de alimentos mais saudáveis foram associados com maior escolaridade e condições de trabalho e renda. Assim como acesso à restaurantes e lanchonetes em indivíduos com melhor poder aquisitivo.
Palavras-Chave: Consumo de alimentos; promoção da saúde; hábitos alimentares.
SOLUÇÃO ESTÉTICA MULTIDISCIPLINAR EM DENTES ANTERIORES: RELATO DE CASO
Authors: Dias Joselúcia , Mainny Diógenes Veras Iasmim , Castillo Dutra Borges Boniek , Karine Cardoso Guimarães de Carvalho Lilian , Vieira de Assunção Isauremi 
Published: October 2020

Introdução: Pacientes com dentes curtos e ameias abertas, relatam muita insatisfação com seu sorriso. A gengivoplastia, quando bem indicada, permite o aumento no tamanho da coroa dentária de forma a reduzir a necessidade de aumento incisal com resina composta. A reanatomização com resinas compostas para fechamento de ameias e aumentos incisais representa uma alternativa conservadora, pois trata-se de uma técnica adesiva direta que pode ser realizada sem nenhum desgaste dentário. Além disso é uma técnica reversível preferível para pacientes jovens. Objetivo: Apresentar um relato de caso clínico de paciente do sexo masculino, 22 anos, insatisfeito com o tamanho, cor e a forma dos seus dentes anteriores. Descrição do Caso: Ao exame clínico foi observado coroa curta, escurecimento fisiológico, espaços interdentais e desalinhamento das bordas incisais. O plano de tratamento proposto foi encaminhar para a gengivoplastia, clareamento dental pela técnica associada e reanatomização estética dos dentes anteriores com resina composta direta estratificada com diferentes camadas e cores, e posterior texturização superficial durante as fases de acabamento e polimento finais. Conclusões: Com a gengivoplastia e as restaurações, obtivemos dentes reanatomizados, reproduzindo naturalidade de forma, textura e cor. Com planejamento e técnica adequada, foi possível restabelecer o sorriso com proporções, forma e naturalidade satisfatórias.
Breakfast Location Effect on Breakfast Quality and Obesity Risk in Saudi Female College Students
Authors: Jalloun Rola A. , Alfadhli Eman M. 
Published: October 2020

Background:
There is a lack of data regarding breakfast consumption and quality
among college students in the Kingdom of Saudi Arabia.

Objective:
The objective of this study was to assess the prevalence of breakfast consumption and
examine the effect of breakfast location on breakfast nutritional quality and obesity risk among female
college students at Taibah University.

Methods:
A total of 658 students participated in this cross-sectional study. Based on the Child and Adult Care Food
Program (CACFP) recommendations, breakfast quality scores were computed by summing the individual food
components and categorizing participants according to tertiles of the breakfast score distribution. Mixed-effects repeatedmeasures models were used to examine BMI categories with increasing tertiles of breakfast quality scores, stratified by
breakfast location.

Results and Discussion:
Approximately 68% of the participants reported having breakfast regularly.
The mean breakfast quality score was determined for students who had breakfast at home (12.5
± 0.11), at college (10.41± 0.06), and in other places (8.19± 0.48). Obesity was associated with lower
average breakfast quality scores based on breakfast location [mean quintile 3 compared with 1
difference: home 13.6 (P < 0.001), college 9.1 (P < 0.001), other 8.6 (P < 0.001)].

Conclusion:
The findings presented here indicated that a high percentage of students consume
breakfast regularly. Students who had breakfast at home had high scores, which indicated good
breakfast quality and a decreased risk of obesity. Further research on breakfast quality is needed in
this area, as it affects the nutritional status and quality of life of the younger population.
Characteristic Imaging Features of Merkel Cell Carcinoma: A Case Report
Authors: Kim Hyun Jin , Lee Kyu-Chong , Kang Chang Ho , Ahn Kyung-Sik , Kim Chul Hwan 
Published: October 2020

Background:
Merkel cell carcinoma (MCC) is a rare primary cutaneous tumor. The standardized
imaging guidelines for the diagnosis of MCC have not been established. We report the
multimodality imaging features of MCC, including CT, MRI, and ultrasound with grayscale and
color Doppler mode as well as the elastography and even a histopathologic confirmation.

Case Report:
We report the case of a 76-year old male patient with MCC on the elbow that was
treated by excision. On MRI, prominent T2 low signal voiding was noted with branching or chaotic
pattern and marked, branching, or chaotic vascularity was also seen on color doppler ultrasound.
Those findings corresponded to histology that showed increased vascularity in stromal tissues of
the tumor and in between the tumor cells.

Conclusion:
A mass in the dermal and subcutaneous layer with marked and branching or chaotic
vascularity may be the unique characteristic that may contribute to early diagnosis of MCC.
Antiviral Activity of Benzotriazole Based Derivatives
Authors: Corona Paola , Piras Sandra , Ibba Roberta , Riu Federico , Murineddu Gabriele , Sanna Giuseppina , Madeddu Silvia , Delogu Ilenia , Loddo Roberta , Carta Antonio 
Published: October 2020

Background:
For the last thirty years, the benzotriazole scaffold has been the object of our group interest and we have already presented some results on the antiviral activity of our compounds.

Objective:
In this article, we conclude the exploration of N-(4-(R-2H-benzo[d][1,2,3]triazol-2-yl)phenyl)-4-R’-benzamides and 1-(4-(R-2H-benzo[d][1,2,3]triazol-2-yl)phenyl)-3-R’-ureas by synthesizing further modified derivatives, in order to have more elements for SARs evaluation.

Methods:
Here, we reported the synthesis and the antiviral screening results of 38 newly synthesized benzotriazole derivatives against a panel of DNA and RNA viruses. We also analyse SARs in comparing these compounds with previously published benzotriazole analogues, taking stock of the situation.

Results:
Among the newly presented derivatives, compounds 17 and 18 were the most active with EC50 6.9 and 5.5 µM, respectively against Coxsackievirus B5 (CV-B5) and 20.5 and 17.5 µM against Poliovirus (Sb-1).

Conclusion:
we can conclude that N-(4-(2H-benzo[d] [1 - 3] triazol-2-yl)phenyl-R-amide is a good chemical scaffold for the development of new antiviral molecules.
Integrated Empirical-mechanical Seismic Vulnerability Analysis Method for Masonry Buildings in Timișoara: Validation based on the 2009 Italian Earthquake
Authors: Chieffo Nicola , Onescu Iasmina , Formisano Antonio , Mosoarca Marius , Palade Marius 
Published: October 2020

Background:
Timisoara is one of the most important Romanina cities, located in the Banat area and characterised by shallow earthquakes with high ground motion vertical component. The seismicity of the area, in accordance with the P-100 Romanian Code, is affected by medium-high hazard level with an expected maximum PGA of 0.20 g.
From a historical-artistic point of view, the city of Timisoara is full of monumental buildings of inestimable values and it was declared as the European Capital of Culture for 2021.

Aims:
The present work aims to investigate the seismic vulnerability of masonry buildings located in the districts of Fabric and Iosefin, which were grouped in typology classes based on the EMS-98 scale according to their geometrical and structural characteristics.

Methods:
The performed vulnerability analysis is based on a combined empirical-mechanical procedure to estimate the propensity at the damage of the buildings surveyed.

Results:
A specific formulation was proposed for typological vulnerability curves of building classes of the examined area, which were calibrated on the basis of the damages detected after occurred earthquakes.

Conclusion:
The proposed formulation was validated from the application to an urban sector of the municipality of San Pio delle Camere (Italy), which was damaged after the 2009 Abruzzo earthquake.
Attitudes of Pregnant Women Towards Antenatal Care Services Provided in Primary Health Care Facilities of Mbombela Municipality, Mpumalanga Province, South Africa
Authors: Drigo Lucia , Luvhengo Masane , Lebese Rachel T. , Makhado Lufuno 
Published: October 2020

Background:
Pregnant woman’s personal experience of antenatal care services can either be positive or negative; however, knowledge and experience appear to be of paramount importance in shaping their attitudes towards any healthcare-related services. This implies that women's experience of antenatal care services may affect their decision for seeking antenatal care in their present pregnancy, which can lead them to delay seeking care.

Purpose:
This study sought to explore the attitudes of pregnant women towards antenatal care services provided in primary health care facilities of Mbombela Municipality, Mpumalanga Province, South Africa.

Methods:
A qualitative exploratory descriptive study design was used for this study. Purposive sampling technique was used to sample pregnant women who fail to attend antenatal services as expected. Data were collected through face to face unstructured in-depth interview. A total of eighteen pregnant women participated in the study until data saturation. Data were analysed using Tech’s method of analysis.

Results:
Results revealed the following theme and sub-themes: Attitudes of pregnant women related to individual perceptions, perceived barriers to utilizing antenatal care services,’ attitudes of healthcare providers, long waiting times in healthcare facilities, lack privacy and confidentiality in healthcare facilities and attitudes of pregnant women related to attendance of antenatal services.

Conclusion:
Attitudes of pregnant women about antenatal care are shaped by their knowledge and previous encounters with the health care services that they had previously received. It is therefore important to provide women-friendly services. It is recommended that health education regarding the importance of antenatal care services must be given to all women daily in the waiting areas of each primary health care facilities, thus, the healthcare providers should promote the active participation of pregnant women during the health education sessions and provide opportunities to ask questions.
Alteration of Activation Energy of a Reaction in the Catalase of Human Erythrocyte by Cimetidine, an In vitro Thermokinetic Study
Authors: Minai-Tehrani Dariush 
Published: October 2020

Background:
Hydrogen peroxide is normally formed during the metabolic pathway of the
body. It is a toxic compound for vital cells, which can oxidize many macromolecules and cause damage
in cells. Catalase can degrade H2O2 in cells and prevent cell injury. Cimetidine is a histamine H2 receptor
blocker which decreases the release of stomach acid and is used for gastrointestinal diseases. Cimetidine
inhibited catalase by mixed inhibition.

Objective:
In this study, the effect of temperature on the binding of cimetidine to human erythrocyte
catalase was investigated and kinetic factors of the binding were determined.

Results:
Dixon plot confirmed the mixed type of inhibition and determined the Ki of the drug. The maximum
activity of the enzyme was observed at 30°C. Arrhenius plot demonstrated that the activation
energy of the enzyme reaction in the absence and presence of cimetidine was about 4.7 and 8.13 kJ/mol,
respectively. The temperature coefficient (Q30-40) was determined as about 1.11 and 1.09 in the absence
and presence of cimetidine.

Conclusion:
Cimetidine was able to increase the activation energy of the reaction of catalase, which
confirmed the inhibition of the enzyme based on the kinetic results.
A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development
Authors: Husted Karina Louise Skov , Fogelstrøm Mathilde , Hulst Pernille , Brink-Kjær Andreas , Henneberg Kaj-Åge , Sorensen Helge Bjarup Dissing , Dela Flemming , Helge Jørn Wulff 
Published: October 2020

Background
Actions to improve healthy aging and delay morbidity are crucial, given the global aging population. We believe that biological age estimation can help promote the health of the general population. Biological age reflects the heterogeneity in functional status and vulnerability to disease that chronological age cannot. Thus, biological age assessment is a tool that provides an intuitively meaningful outcome for the general population, and as such, facilitates our understanding of the extent to which lifestyle can increase health span.

Objective
This interdisciplinary study intends to develop a biological age model and explore its usefulness.

Methods
The model development comprised three consecutive phases: (1) conducting a cross-sectional study to gather candidate biomarkers from 100 individuals representing normal healthy aging people (the derivation cohort); (2) estimating the biological age using principal component analysis; and (3) testing the clinical use of the model in a validation cohort of overweight adults attending a lifestyle intervention course.

Results
We completed the data collection and analysis of the cross-sectional study, and the initial results of the principal component analysis are ready. Interpretation and refinement of the model is ongoing. Recruitment to the validation cohort is forthcoming. We expect the results to be published by December 2021.

Conclusions
We expect the biological age model to be a useful indicator of disease risk and metabolic risk, and further research should focus on validating the model on a larger scale.

Trial Registration
ClinicalTrials.gov NCT03680768, https://clinicaltrials.gov/ct2/show/NCT03680768 (Phase 1 study); NCT04279366 https://clinicaltrials.gov/ct2/show/NCT04279366 (Phase 3 study).

International Registered Report Identifier (IRRID)
DERR1-10.2196/19209
Development of a Web-Based Mindfulness Program for People With Multiple Sclerosis: Qualitative Co-Design Study
Authors: Sesel Amy-Lee , Sharpe Louise , Beadnall Heidi N , Barnett Michael H , Szabo Marianna , Naismith Sharon L 
Published: October 2020

Background
Mindfulness-based stress reduction is an efficacious treatment for people with chronic health problems; however, it is highly intensive and time-consuming, which is a barrier for service provision.

Objective
This study aims to develop an internet-delivered adapted version of mindfulness-based stress reduction for people with multiple sclerosis to make the intervention more accessible.

Methods
We co-designed a web-based mindfulness program with end users, that is, people with multiple sclerosis (N=19). Iterative feedback was also collected from a subsample of the initial group of end users (n=11), and the program was reviewed by experts (n=8).

Results
We identified three main themes common to people with multiple sclerosis: dealing with uncertainty and fears for the future, grief and loss, and social isolation. These themes were incorporated into narratives throughout the program. People with multiple sclerosis who reviewed the program gave feedback that the program was relatable, feasible, and acceptable. Experts agreed that the program appropriately represented the main tenets of mindfulness. Iterative feedback was used to further refine the program.

Conclusions
The web-based mindfulness program that we developed was viewed positively by both experts and end users. The program reflects common concerns for people with multiple sclerosis and has the potential to meet important unmet psychological needs. A randomized controlled trial was planned to determine the efficacy of the program.
Screening for Depression in Daily Life: Development and External Validation of a Prediction Model Based on Actigraphy and Experience Sampling Method
Authors: Minaeva Olga , Riese Harriëtte , Lamers Femke , Antypa Niki , Wichers Marieke , Booij Sanne H 
Published: October 2020

Background
In many countries, depressed individuals often first visit primary care settings for consultation, but a considerable number of clinically depressed patients remain unidentified. Introducing additional screening tools may facilitate the diagnostic process.

Objective
This study aimed to examine whether experience sampling method (ESM)-based measures of depressive affect and behaviors can discriminate depressed from nondepressed individuals. In addition, the added value of actigraphy-based measures was examined.

Methods
We used data from 2 samples to develop and validate prediction models. The development data set included 14 days of ESM and continuous actigraphy of currently depressed (n=43) and nondepressed individuals (n=82). The validation data set included 30 days of ESM and continuous actigraphy of currently depressed (n=27) and nondepressed individuals (n=27). Backward stepwise logistic regression analysis was applied to build the prediction models. Performance of the models was assessed with goodness-of-fit indices, calibration curves, and discriminative ability (area under the receiver operating characteristic curve [AUC]).

Results
In the development data set, the discriminative ability was good for the actigraphy model (AUC=0.790) and excellent for both the ESM (AUC=0.991) and the combined-domains model (AUC=0.993). In the validation data set, the discriminative ability was reasonable for the actigraphy model (AUC=0.648) and excellent for both the ESM (AUC=0.891) and the combined-domains model (AUC=0.892).

Conclusions
ESM is a good diagnostic predictor and is easy to calculate, and it therefore holds promise for implementation in clinical practice. Actigraphy shows no added value to ESM as a diagnostic predictor but might still be useful when ESM use is restricted.
Transisi Sosial Budaya Adat Pernikahan Suku Bugis Di Makassar 1960
Authors: R. A. Fadhilah Utami Ilmi 
Published: October 2020

Berkembangnya pendidikan di Kota Makasar pada tahun 1960 mampu merubah budaya adat pernikahan Suku Bugis yang sangat mahal dan tatacara yang rumit menjadi lebih sederhana. Tata cara pernikahan yang rumit dan mahal tersebut dipengaruhi oleh ideologi adat pernikahan yang sangat memperhatikan “Siri” yang berarti harga diri dan “Messe” yang berarti peduli pada orang lain.
Pernikahan Adat Bugis harus melalui berbagai tahapan yaitu Mammanu ‘manu’ yaitu mencarikan jodoh untuk anak laki-laki, Mappese ‘pese’ yaitu menyelidiki calon pengantin perempuan, Massaro yaitu meminang, Mappetu Ada yaitu menentukan hari pernikahan, uang belanja serta mahar, Mappare Boting yaitu mengantarkan pengantin laki-laki ke pengantin perempuan dan Mapparola yaitu mengantarkan pengantin perempuan ke keluarga pengantin laki-laki. Proses ini dilakukan dalam jangka waktu yang lama dan membutuhkan biaya besar. Di samping biaya tersebut pengantin laki-laki juga dibebani uang ‘Panai’ (mahar) yang sangat mahal tergantung kondisi sosial ekonomi pengantin perempuan.
Studi Pustaka yang dilakukan menunjukkan majunya pendidikan di Kota Makasar yang ditandai dengan berdirinya Universitas Negeri Makasar (UNHAS) pada tahun 1956 dan Universitas Negeri Makasar (UNM) pada tahun 1961 berdampak pada majunya pendidikan masyarakat setempat dan mampu merubah pola pikir masyarakat tentang adat pernikahan. Perubahan yang terjadi adalah penyederhanaan tatacara pernikahan dan penentuan uang panai yang semakin murah.