bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renewables‐based decarbonization and relocation of iron and steel making: A case study
Authors: Gielen Dolf , Saygin Deger , Taibi Emanuele , Birat Jean‐Pierre 
Published: March 2020

AbstractThe article assesses the future role of hydrogen‐based iron and steel making and its potential impact on global material flows, based on a combination of technology assessment, material flow analysis, and microeconomic analysis. Renewable hydrogen‐based iron production can become the least‐cost supply option at a carbon dioxide (CO2) price of around United States dollars (USD) 67 per tonne. Availability of low‐cost renewable electricity is a precondition. Australia is the world's largest producer of iron ore and at the same time a country with significant low‐cost renewable electricity potential. A shift to direct reduced iron (DRI) exports could reduce global CO2 emissions substantially and at the same time increase value added in Australia, while maintaining steel production in countries that are currently processing ore into iron and steel, such as China, South Korea, and Japan. The approach could be expanded to other parts of the world and other energy‐intensive industry sectors. Such relocation analysis in a climate context can become a new industrial ecology research area. Iron and steel industry CO2 emissions can be reduced by nearly a third, around 0.7 gigatonnes (Gt) CO2 per year. To achieve these emission reductions, investment of USD 0.9 trillion, or 0.7% of the total energy sector investment needs, would be required, global DRI production would have to increase seven‐fold from today's level, and the hydrogen energy used would equal 1% of global primary energy supply. Such a shift could develop from 2025 onward at scale, if the right policies are put in place.
Attenuation correction for confocal laser scanning microscopy and its application in chromatography
Authors: OHSER J. , HAAS P. , FAHRBACH F. , MENSTELL P. , SCHWÄMMLE A. , OSTERROTH S. , DOBROVOLSKIJ D. 
Published: March 2020

SummaryThe applicability of confocal laser scanning microscopy is limited, e.g. by attenuation of the excitation and the fluorescence emission beam. As a prerequisite for further processing and analysis of the obtained microscopic images, a new method is presented for correcting this attenuation. The correction is based on beam modelling and on a differential form of the modified Beer–Lambert law. It turns out that the intensity decay can be modelled as a double convolution of the microscopic image with the intensities of the excitation semibeam and the emission beam. Under weak assumptions made for the intensities of the fluorescent radiation and the detected signal, formulas for the attenuation correction and the attenuation simulation are derived. The method traces back to that one published by Roerdink which is modified concerning a more realistic beam modelling, avoiding the so‐called weak attenuation expansion and considering fluorescence excitation throughout the light cone of the excitation beam. The applicability of the method is demonstrated for synthetic examples as well as microscopic images of chromatographic beads. It is shown that the new method can be successfully applied for reconstructing the true fluorophore distribution in specimens even if the microscopic images are affected by strong attenuation.Lay DescriptionThe applicability of confocal laser scanning microscopy is limited by attenuation of the excitation and the fluorescence emission beam. As a prerequisite for further processing and analysis of the obtained microscopic images, a new method is presented for correcting this attenuation. The correction is based on modeling the excitation as well as the emission beam and on a modified Beer‐Lambert law for beam attenuation. The applicability of the method is demonstrated for synthetic examples as well as microscopic images of chromatographic beads. It is shown that the new method can be successfully applied for reconstructing the true fluorophore distribution in specimens even if the microscopic images are affected by strong attenuation.
Examining subacute nurses’ roles in a changing healthcare context
Authors: Digby Robin , Bolster Danielle , Hughes Leanne , Perta Andrew , Bucknall Tracey K. 
Published: March 2020

AbstractAims and objectivesTo explore and describe nurses' role in the rehabilitation and care of patients in one subacute care facility in Melbourne, Australia.BackgroundThe role of nurses in subacute care and within the rehabilitation team is evolving and remains unclear.DesignMixed methods.MethodsFourteen nurses from seven rehabilitation and geriatric evaluation and management wards in one subacute facility in Melbourne, Australia, were observed in practice for two hours and then interviewed. Activities were recorded electronically. Interviews were audio‐recorded and transcribed. Data were analysed using content analysis. The study complied with the Consolidated Criteria for Reporting Qualitative Research (COREQ).ResultsThree main themes are as follows: (a) Nurses as rehabilitators; (b) Teamwork in rehabilitation; and (c) The changing context of subacute care. Nurses prioritised patient personal and clinical care above other responsibilities. They were largely excluded from team decision‐making because clinical responsibilities precluded them from attending team meetings. Unsuitable buildings, increased patient acuity and time constraints were further challenges.ConclusionsNurses have a multifaceted role in patient rehabilitation that is poorly understood. An evaluation of the nursing role within the interdisciplinary team, skills and processes of care may increase understanding, and improve communication and relationships between disciplines potentially benefiting patients. Role clarity and differentiation in nursing skills are required within the nursing workforce.Relevance to clinical practice

Nurses have a unique role in both clinical care and rehabilitation of patients, and as part of the interdisciplinary team.

Respectful professional relationships need fostering within the interdisciplinary team to achieve optimal patient outcomes.

The way that team meetings and decision‐making occur in the subacute wards requires adjustment to ensure that the valuable contribution of nurses, both to the interdisciplinary team and to the rehabilitation of patients, is used and acknowledged to improve patient care.
Clinical outcomes of transarterial chemotherapy and embolization for vaginal cancer
Authors: Bi Yonghua , Yi Mengfei , Yu Zepeng , Han Xinwei , Ren Jianzhuang 
Published: March 2020

AbstractAimWe report clinical outcomes of transarterial embolization in 19 cases of vaginal cancer.MethodsFrom August 2011 to October 2019, 19 patients with histologically diagnosed vaginal cancer were identified in our department. Transarterial chemotherapy and embolization was performed for all patients. Patient characteristics, treatment plans and the clinical outcomes, were recorded.ResultsAmong 19 identified cases, nine of them are squamous cell carcinoma, five of adenocarcinoma, one of adenosquamous carcinoma, two of vaginal malignant melanoma, one leiomyosarcoma and one of stromal sarcoma. Transarterial chemotherapy and embolization was successfully performed in all patients. No related complication was found after intervention treatment. Besides, eight patients received adjuvant chemotherapy, four received both adjuvant chemotherapy and radiotherapy and seven received no therapies. Four patients were cured and seven were stable during follow‐up.ConclusionTransarterial embolization appears safe and effective for vaginal cancer, with a currently acceptable prognosis.
Digitally Created 3‐Piece Additive Manufactured Index for Direct Esthetic Treatment
Authors: Park So Hyeon , Piedra‐Cascón Wenceslao , Zandinejad Amirali , Revilla‐León Marta 
Published: March 2020

AbstractFacial and intraoral scanners as well as additive manufacturing (AM) technologies can be integrated to virtually plan restorative procedures. The present article describes a digital workflow protocol for treatment planning an esthetic rehabilitation using direct composite restorations. The combination of facial digitalization and intraoral scans allowed a facially driven diagnostic waxing, while additive manufacturing technologies facilitate the translation of the digital waxing into the patient´s mouth through an AM 3‐piece silicone index which was designed into a buccal and a lingual clear flexible silicone indices that were fitted into a clear and rigid custom tray. This procedure facilitated the treatment planning procedures as well as assisted the direct composite restoration procedures, providing several advantages compared with conventional procedures such as precise translation of the digital diagnostic waxing into the patient´s mouth, horizontal path of insertion of the silicone index, and minimized time of the clinical intervention.
Being fun: An overlooked indicator of childhood social status
Authors: Laursen Brett , Altman Robert L. , Bukowski William M. , Wei Li 
Published: March 2020

AbstractObjectiveThe present study concerns an overlooked trait indicator of childhood peer status: Being fun. The study is designed to identify the degree to which being fun is uniquely associated with the peer status variables of likeability and popularity.MethodTwo studies of children in grades 4 to 6 (ages 9 to 12) are reported. The first involved 306 girls and 305 boys attending school in northern Colombia. The second involved 363 girls and 299 boys attending school in southern Florida. Students completed similar peer nomination inventories, once in the first study and twice (8 weeks apart) in the second.ResultsIn both studies, being fun was positively correlated with likeability and popularity. In the second study, being fun predicted subsequent changes in likeability and popularity, after controlling for factors known to be related to each. Initial likeability and popularity also predicted subsequent changes in perceptions of being fun.ConclusionsAnecdotal evidence suggests that children are intensely focused on having fun. The findings indicate that this focus extends beyond the immediate rewards that fun experiences provide; some portion of peer status is uniquely derived from the perception that one is fun to be around.
RIASEC interests and the Big Five personality traits matter for life success—But do they already matter for educational track choices?
Authors: Usslepp Nele , Hübner Nicolas , Stoll Gundula , Spengler Marion , Trautwein Ulrich , Nagengast Benjamin 
Published: March 2020

AbstractObjectiveEducational track choices have far‐reaching consequences because they are associated with long‐term life success. Theoretical approaches and previous empirical research have nearly exclusively identified family background and achievement as determinants of these choices. Although students’ educational track choices might fit their personality, individual differences in personality have not been explored. We investigated the effects of two personality aspects—RIASEC interests and Big Five traits—on hierarchically ranked track choices (vocational vs. general educational track), alongside family background and achievement.MethodWe used two German data sets (TOSCA 10 study: N = 473; TOSCA study: N = 4,218) focusing on choices between the general educational track (leading to higher educational attainment) and the vocational track (leading to work life) at two different stages in educational careers. We ran several multiple (logistic) regressions.ResultsThe results showed that certain aspects of students’ personality matter for educational track choices. Accordingly, across both studies, students with high Investigative or Enterprising interests more often chose the general educational track, whereas students with high Social or Conventional interests more often chose the vocational track—after the Big Five personality traits, achievement, and family background were controlled for. The Big Five traits showed no or only small significant associations with educational track choices.ConclusionThese findings underscore the importance of considering individual differences when investigating important life outcomes such as track choices.
Clomipramine, a tricyclic antidepressant, and selegiline, a monoamine oxidase-B inhibitor, modulate the activity of phagocytic cells after oral administration in mice
Authors: Sobieszczańska Anna , Lis Magdalena , Suszko-Pawłowska Agnieszka , Szczypka Marianna 
Published: March 2020

Abstract

Objectives
Our aim was to find out whether clomipramine, a tricyclic antidepressant, and selegiline, a monoamine oxidase-B inhibitor, influence the activity of phagocytic cells after in-vivo administration in mice.

Methods
Clomipramine and selegiline were administered to Balb/c mice orally at a dose of 1 mg/kg, 7 or 14 times. IL-1β and nitric oxide (NO) levels were measured in supernatants of the peritoneal macrophage cultures stimulated in vitro with lipopolysaccharide from Escherichia coli. The phagocytic activity of the granulocytes and monocytes was determined using a commercial Phagotest 24 and 72 h after the last dose of the investigated drugs.

Key findings
Seven doses of clomipramine or selegiline decreased IL-1β production, while a rise in its synthesis was observed after 14 doses of selegiline. Clomipramine administered 14 times increased NO production. Clomipramine and selegiline administered seven times reduced the percentage of phagocytosing granulocytes. The drugs administered 14 times increased the percentage of phagocytosing granulocytes and decreased the percentage of phagocytosing monocytes.

Conclusions
Both clomipramine and selegiline administered in vivo changed the phagocytic activity of blood cells and IL-1β and NO production by murine peritoneal macrophages. This effect depended on the drug, the number of doses and the type of phagocytic cells.
Addition of magnesium sulfate to intraperitoneal ropivacaine for perioperative analgesia in canine ovariohysterectomy
Authors: Gomes Denis R. , Nicácio Isabela P. G. A. , Cerazo Letícia M. L. , Dourado Larissa , Teixeira‐Neto Francisco J. , Cassu Renata N. 
Published: March 2020

AbstractMagnesium may be used as an adjunctive analgesic for perioperative pain management because of its antinociceptive properties. This study investigated the analgesic efficacy of intraperitoneal ropivacaine combined with magnesium sulfate in canine ovariohysterectomy. Forty‐five dogs sedated with acepromazine/meperidine and anesthetized with propofol/isoflurane were randomly distributed into three treatments, administered intraperitoneally (n = 15 per group): saline solution (group S), 0.25% ropivacaine (3 mg/kg) alone (group R), or in combination with magnesium sulfate (20 mg/kg, group R‐Mg). Intravenous fentanyl was given to control cardiovascular responses to surgical stimulation. Postoperative pain was assessed using an Interactive Visual Analog Scale (IVAS), the short form of the Glasgow Composite Pain Scale, and mechanical nociceptive thresholds. Morphine/meloxicam was administered as rescue analgesia. Intraoperatively, the R‐Mg group required less fentanyl (p = .02) and exhibited higher incidence of hypotension (systolic arterial pressure <90 mm Hg, p = .006) compared with the S group. Lower IVAS pain scores were recorded during the first hour in the R‐Mg group than the other groups (p = .007–.045). Postoperative rescue analgesia did not differ between groups. Intraperitoneal magnesium sulfate administration, in spite of decreasing intraoperative opioid requirements, increased the incidence of hypotension with minimal evidence of postoperative analgesic benefits.
Diagnostic Performance of CT/MRI Liver Imaging Reporting and Data System v2017 for Hepatocellular Carcinoma: A Systematic Review and Meta‐Analysis
Authors: Lee Sunyoung , Kim Seung‐Seob , Roh Yun Ho , Choi Jin‐Young , Park Mi‐Suk , Kim Myeong‐Jin 
Published: March 2020

AbstractBackground & AimsThe liver Imaging Reporting and Data System (LI‐RADS) is a comprehensive system for standardizing liver imaging in patients at high risk for hepatocellular carcinoma (HCC). We performed a meta‐analysis to determine the diagnostic performance of the LR‐5 category for HCC and the pooled proportions of HCCs in each LI‐RADS category using CT/MRI LI‐RADS v2017.MethodsWe searched multiple databases for original studies reporting on the diagnostic accuracy of CT/MRI LI‐RADS v2017. Random‐effects models were used to determine the summary estimates of the diagnostic performance of the LR‐5 category and the pooled proportions of HCCs for each LI‐RADS category. Risk of bias and concerns regarding applicability were evaluated with the Quality Assessment of Diagnostic Accuracy Studies‐2 tool.ResultsFourteen studies (3 prospective studies and 11 retrospective studies) were included in the final analysis, consisting of 2056 patients, 2589 observations, and 1693 HCCs. The pooled per‐observation sensitivity was 67% (95% confidence interval [CI], 62%‐72%) with specificity of 92% (95% CI, 88%‐95%) in the LR‐5 category of CT/MRI LI‐RADS v2017 for diagnosing HCC. The pooled proportions of HCCs were 0% (95% CI, 0%‐0%) for LR‐1, 4% (95% CI, 0%‐8%) for LR‐2, 34% (95% CI, 23%‐44%) for LR‐3, 67% (95% CI, 53%‐81%) for LR‐4, and 92% (95% CI, 87%‐96%) for LR‐5. The proportions of HCCs were significantly different among LI‐RADS categories 1‐5 (P = .034).ConclusionsThe LR‐5 category of CT/MRI LI‐RADS v2017 shows moderate sensitivity and high specificity for diagnosing HCC. Higher LI‐RADS categories contained higher proportions of HCCs.
Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
Authors: Isanaka Sheila , Andersen Christopher T. , Hanson Kerstin E. , Berthé Fatou , Grais Rebecca F. , Briend André 
Published: March 2020

AbstractOutpatient therapeutic feeding protocols for the treatment of uncomplicated severe acute malnutrition in children were initially based on weight gain data from inpatient settings and expert knowledge of the physiological requirements during recovery. However, weight gain and energy requirements from historic inpatient settings may differ from modern outpatient settings and therefore may not be appropriate to guide current therapeutic feeding protocols. We calculated the weight gain and average estimated total daily energy requirement of children successfully treated for uncomplicated severe acute malnutrition as outpatients in Niger (n = 790). Mean energy provided by six therapeutic feeding protocols was calculated and compared with average estimated energy requirements in the study population. Overall weight gain was 5.5 g·kg−1·day−1 among recovered children. Average energy requirements ranged from 92 to 110 kcal·kg−1·day−1 depending on the estimation approach. Two current therapeutic feeding protocols were found to provide an excess of energy after the first week of treatment in our study population, whereas four research protocols tended to provide less energy than the estimated requirement after the first week of treatment. Alternative feeding protocols have the potential to simplify and lead to important savings for programmes but should be evaluated to show adequacy to meet the energy needs of children under treatment, as well as feasibility and cost efficiency. Our findings rely on theoretical calculations based on several assumptions and should be confirmed in field studies.
Contrasting genomic and phenotypic outcomes of hybridization between pairs of mimetic butterfly taxa across a suture zone
Authors: Gauthier Jérémy , de Silva Donna Lisa , Gompert Zachariah , Whibley Annabel , Houssin Céline , Le Poul Yann , McClure Melanie , Lemaitre Claire , Legeai Fabrice , Mallet James , Elias Marianne 
Published: March 2020

AbstractHybrid zones, whereby divergent lineages come into contact and eventually hybridize, can provide insights on the mechanisms involved in population differentiation and reproductive isolation, and ultimately speciation. Suture zones offer the opportunity to compare these processes across multiple species. In this paper we use reduced‐complexity genomic data to compare the genetic and phenotypic structure and hybridization patterns of two mimetic butterfly species, Ithomia salapia and Oleria onega (Nymphalidae: Ithomiini), each consisting of a pair of lineages differentiated for their wing colour pattern and that come into contact in the Andean foothills of Peru. Despite similarities in their life history, we highlight major differences, both at the genomic and phenotypic level, between the two species. These differences include the presence of hybrids, variations in wing phenotype, and genomic patterns of introgression and differentiation. In I. salapia, the two lineages appear to hybridize only rarely, whereas in O. onega the hybrids are not only more common, but also genetically and phenotypically more variable. We also detected loci statistically associated with wing colour pattern variation, but in both species these loci were not over‐represented among the candidate barrier loci, suggesting that traits other than wing colour pattern may be important for reproductive isolation. Our results contrast with the genomic patterns observed between hybridizing lineages in the mimetic Heliconius butterflies, and call for a broader investigation into the genomics of speciation in Ithomiini ‐ the largest radiation of mimetic butterflies.
Age structure of strandings and growth of Lahille's bottlenose dolphin (Tursiops truncatusgephyreus)
Authors: Venuto Rihel , Botta Silvina , Barreto André S. , Secchi Eduardo R. , Fruet Pedro F. 
Published: March 2020

AbstractThis study describes the age structure and sex‐specific growth patterns of Lahille's bottlenose dolphins (Tursiops truncatus gephyreus), a subspecies endemic to the Southwest Atlantic Ocean (SWAO). The ages of 120 animals collected in southern Brazil between 1976 and 2017 were determined. We found high frequencies of young animals, mostly males, with no sex bias among adults. A temporal change in the age structure of strandings was observed, and we conclude it is a consequence of increased bycatch rates of young dolphins after 2000. The oldest male and female were 27 and 44 years old, respectively, suggesting that females live longer than males in southern Brazil. Growth curve analysis using Gompertz and Laird‐Gompertz growth models estimated asymptotic lengths of 316.5 cm for females and 351.6 cm for males, (reached around 13 and 18 years old, respectively), supporting sexual size dimorphism for the subspecies. A second growth pulse was identified for males. Our work highlights the benefit of long‐term studies and contributes valuable information toward understanding the life history of Lahille's bottlenose dolphin. It will serve as baseline for future studies that seek to understand mortality patterns of bottlenose dolphins elsewhere and the effects of anthropogenic actions on the survival of these animals.