bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experience in endoscopic treatment of patients with adrenal neoplasms
Authors: Stegniy K. V. , Kulakova T. A. , Dvoinikova E. R. , Goncharuk R. A. , Morozova A. M. , Tsygankova O. G. , Krekoten A. A. , Dmitriev M. O. , Soroka A. K. , Morgun A. A. 
Published: November 2020

Objective: To summarize the experience of endoscopic surgical treatment of patients with adrenal neoplasms.Methods: The results of treatment of 80 patients (64 women and 16 men) with adrenal neoplasm were retrospectively analyzed in Medical Center, Far Eastern Federal University, from 2014 to 2019.Results: Andrenalectomies were performed via three accesses: laparoscopic (49 cases), retroperitoneoscopic (22 cases) and laparoscopy-assisted (6 cases). Three cases required conversion. 70 benign and 10 malignant neoplasms were removed. Complications, including one death, developed in four cases.Conclusions: Minimally invasive andrenalectomy is safer and more preferable than open surgery due to reduced duration of hospital stay, decreased rate of complications, degree of pain syndrome, extent of blood loss and need for opioid analgesics.
The dynamics of chorioretinal hemodynamics after courses of preventive care in women at risk for the formation of vascular retinal pathology
Authors: Kolenko O. V. , Sorokin E. L. , Fil A. A. 
Published: November 2020

Objective:Clinical assessment of chorioretinal hemodynamics in women at risk for vascular retinal pathology before and after long-term courses of preventive care.Methods: 60 women having undergone preeclampsia during pregnancy were exam‑ ined. The 1st group of patients (30 people) got courses of medicamentous correction of endothelial dysfunction: sulodexide, ginkgo biloba (Tanakan), ascorbic acid. The 2nd group (30 women) did not get preventive care. The control group included 30 women having undergone physiological pregnancy (vaginal delivery, without complications). Parameters of chorioretinal hemodynamics were determined 6–8 months later and 3–4.5 years later after delivery.Results: By the end of the follow-up, in the 1st group, the blood flow velocity in the posterior short ciliary arteries statistically significantly increased; the density of the retinal vessels and subfoveolar thickness of the choroid and the area of the avascular zone of the retina decreased.Conclusions: The long-term medicamentous correction of endothelial dysfunction reduces the risk of vascular pathology development in women having undergone preeclampsia during the pregnancy.
Evaluation of the efficacy of neural network technology in the analysis of the condition of the optic nerve disc and peripapillary retina in healthy individuals examined for glaucoma
Authors: Movsisyan A. B. , Kuroyedov A. V. , Gorodnichy V. V. , Ostapenko G. A. , Podvigin S. V. , Rachinsky Yu. A. , Lanin S. N. 
Published: November 2020

Objective: Evaluation of efficacy of the application of artificial intelligence technology and neural networks in the analysis of the condition of the optic disc and the peripapillary retina in healthy individuals.Methods: Prospective analysis of the condition of visual organs in 54 patients aged from 49 to 71 years (100 eyes) was conducted. The examination included autorefractometry, visometry, tonometry, automated perimetry, spectral domain optical coherence tomography, Heidelberg retina tomography. A pre-trained neural network evaluated only a photograph of the optic nerve disc and the peripapillary retina.Results: Neural network identified twelve images with suspected glaucoma, five of which were selected by medical experts. The comparison of all study groups has demonstrated the presence of statistically significant differences between them according to a range of visiometric indicators.Conclusions: The study results showed high efficiency of artificial intelligence and the prospects of its use for the diagnosis of glaucoma.
C-reactive protein and procalcitonin in biological liquids in men with normal and reduced fertility
Authors: Sosnin D. Yu. , Galkovich K. R. , Krivtsov A. V. 
Published: November 2020

Objective:A comparative analysis of C-reactive protein (CRP) and procalcitonin concentration in blood serum and seminal plasma of healthy men and men with reduced concentration of sperm cells.Methods: 73 fertile men were examined. The experimental group included 36 patients with a reduced fertility; the comparison group (control) included 37 men with normal indicators of ejaculate composition. The concentrations of CRP and procalcitonin were determined by the method of enzyme-linked immunosorbent assay.Results: Differences in level of CRP between blood serum and seminal plasma in experimental and control groups occurred to be statistically significant in both groups. There was no correlation between these parameters. The concentration of procalcitonin was almost ten times higher in the seminal plasma than in the blood serum. In the experimen‑ tal group, it was significantly higher in ejaculate than in the comparison group. The concentration of CRP and procalcitonin did not correlate neither with the ejaculate volume nor with concentration or amount of sperm cells in it.Conclusions: The levels of CRP and procalcitonin in seminal plasma can indicate the fertility status of the ejaculate.
Emergence agitation after ophthalmic surgery in preschool age children: Causes, prevention options
Authors: Utkin S. I. , Bachinin E. A. , Stolyarov M. V. , Ignatenko D. Yu. , Khalfin R. N. 
Published: November 2020

Objective: Analysis of the frequency and clinical manifestations of emergence agitation in children with background psycho‑ neurological disorders after general inhalational anesthesia during ophthalmic surgery.Methods: 1155 children aged 2–6 years having undergone different ophthalmic surgeries were examined. Children were conventionally divided into two groups: a main one (n=516) – children with different psychoneurological disorders; a comparison one (n=639) – children without psy‑ choneurological disorders. All patients got the general inhalational anesthesia with sevoflurane. The induction was performed intravenously with propofol.
Key factors of inflammation and long-term prognosis in patients with myocardial infarction and visceral obesity
Authors: Uchasova E. G. , Belik E. V. , Gruzdeva O. V. , Dileva Y. A. , Kuzmina A. A. 
Published: November 2020

Objective: To assess the relation between key factors of inflammation and myocardial infarction complications in different stages of the diseases in patients with visceral obesity.Methods: Men with the diagnosed myocardial infarction were examined: 64 of them with visceral obesity (the first group) and 30 of them without visceral obesity (the second group). On the 1s t and 12th day of hospitalization, the serum concentrations of interleukins (IL) 1β, 6, 8, 10 and 12, tumor necrosis factor α (TNFα) and C-reactive protein (CRP) were determined. The control group included 30 healthy men.Results: The cytokine profile in visceral obesity was characterized by the increase in concentration of proinflammatory ILs and the decrease in concentration of IL-10. The concentration increase was: 1.3 times for IL-1 and TNFα, 2 times for IL-12, 6 times for IL-6 and 24 times for IL-8 and CRP. The increase in IL-6 and CPR levels in blood serum was associated with the obesity.Conclusions: The development of adverse cardio‑ vascular complications a year later after the previous myocardial infarction is typical for patients with visceral obesity and is followed by the activation of proinflammatory cytokines and deficiency of IL-10.
Radiation therapy and breast reconstruction
Authors: Apanasevich V. I. , Gulian I. S. , Nikiforova N. O. , Petukhova Y. Y. , Korshunova O. V. , Kustov V. N. , Temchenco V. V. 
Published: November 2020

Radiation therapy is an integral component of the treatment of breast cancer. Although its implementing after breast reconstruction sufficiently increases the number of complications, particularly capsular contractures. After having analyzed published materials and meta-analysis research the authors made a conclusion – if a patient is planned to have a breast reconstruction, it’s better to make it with her own tissue. On the other hand the risk of capsular contractures development significantly decreases when using acellular matrix and polyurethane shell to cover the implant. This fact gives hope that conflict between breast reconstruction and the necessity of the radiation therapy can be solved.
Cancer patients having COVID-19 in Primorsky region: Morbidity and mortality
Authors: Fateeva A. V. , Gurina L. I. 
Published: November 2020

In the end of the year 2019 there was an outbreak of the new coronavirus infection with the epicenter in China, Wuhan (Hubei province). On 11th of February WHO defined an official name of the infection generated by new coronavirus – COVID-19 (COronaVIrus Disease 2019). On the 11th of February the International Committee on Virus Taxonomy assigned the name to the causative agent – SARS-CoV-2. The emergence of the COVID-19 set the task to the medical specialists connected with the fast diagnostics and providing medical treatment to the patients. Currently the intensive study of the clinical and epidemiological peculiarities of the disease, the development of new ways of prevention and treatment is the ongoing process. In this article the results of the morbidity and death rates connected with COVID-19 of the patients having cancer in Primorskiy region from 31st of March to 31st of August 2020 are introduced.
Antitumor activity of pectins of various molecular weights
Authors: Leonteva E. A. , Vikhareva V. V. , Kalitnik A. A. , Khotimchenko M. Yu. 
Published: November 2020

Objective: Comparative analysis of the antitumor characteristics of different pectins and the dependency of their biological effects on the structural features and the molecular weight.Methods: Cell lines of the murine adenocarcinoma of the mammary gland C127, carcinoma of the cervix HeLa, adenocarcinoma of the colon SW620, adenocarcinoma of the mammary gland HTB-30 and the normal cells of the retina RPE were used to study the antitumor activity of the polysaccharides. The assessment of the antitumor and cytotoxic actions of the pectins was made by testing metabolic activity through MTT-assay and by making intravital fluorescent coloring of the live and dead cells using DNA-connecting color Hoechst and propidium iodide.Results: The samples of the citrus pectins in the selected concentration range had a sufficient antitumor effect on the adenocarcinoma C127 cell line by decreasing metabolic activity and the cell proliferation, and also by providing cilinically important cytotoxic effect.Conclusions: The data got in this study demonstrates that the reaction of the cancer cells on pectins depends on the type of the connection used and also on the sensitivity of the cells to pectins.
Evaluation of molecular changes in the mucous membrane close to the resection margin after surgical treatment for gastric cancer
Authors: Reshetov I. V. , Bykov I. I. , Mikerova M. S. , Nemtsova M. V. 
Published: November 2020

Objective: Secretion of the changes characterizing genetic instability of the gastric mucosa when having esophagus cancer.Methods: 64 patients having esophagus cancer (main group) and 50 patients having gallstone disease were examined. They were undergoing treatment in the hospital No. 1 of the I.M. Sechenov First Moscow State Medical University. In all cases molecular tumor markers in the gastric mucosa after operation and biopsy were examined.Results: Esophagus cancer turned out to be characterized by high frequency of RASSF1А and MLH1 genes methylation and high hTERT, MMP7 and BIRC5 genes expression, and also by high telomerase activity. There was also high frequency of TUSC3, CDH1 and DAPK genes methylation inside gastric mucosa approached to the edge of resection.Conclusions: The study of the frequency of TUSC3, CDH1, DAPK, RASSF1А and MLH1 genes methylation and telomerase activity can be used as clinical markers defining changes in gastric mucosa after its resection concerning cancer.
The possibility of using tantalum oxide microparticles in phosphate glass for radiation therapy of malignant neoplasms
Authors: Plotnikova O. S. , Apanasevich V. I. , Medkov M. A. , Polezhaev A. A. , Nevozhai V. I. , Argishev O. A. 
Published: November 2020

Objective: The creation of the medicine for a local radiomodification of tumors.Methods: The level of the secondary radiation on the surface of the phosphate glass powder with the inclusion of tantalum oxide processed by 6 MeV deceleration emission was studied. Medical linear accelerator TrueBeam (Varian, USA), and Semiconductor diode detector PDI 2.0 (Sun Nuclear Corp., USA) having the system of moving in vertical plane and the system of position video recording were used.Results: The presence of the phosphate glass (containing 20% Та2О5) on the surface gave a 63.7% increase to the secondary radiation. It’s around two thirds of the overall level.Conclusion: An opportunity to create a medicine on the basis of phosphate glass, containing tantalum oxide, for local radiomodification of malignant tumors.
PENERAPAN METODE EXTREME PROGRAMMING SMARTSCHOOL PADA SMK NUSANTARA 1 KOTABUMI
Authors: Parida Merri , Ali Ahmad Basori 
Published: November 2020

Proses belajar-mengajar yang sedang berjalan pada sekolah SMK Nusantara 1 Kotabumi masih bersifat konvensional yaitu guru menyampaikan materi pelajaran, tugas, kuis, pengumpulan tugas di kelas dan setiap mata pelajaran hanya dilakukan beberapa kali pertemuan seminggu dengan waktu yang terbatas. Tujuan penelitian ini adalah penerapan metode extreme programming smartschool pada SMK Nusantara 1 Kotabumi untuk mengatasi berbagai persoalan yang dihadapi oleh sekolah SMK Nusantara 1 Kotabumi.
Rancang bangun software smartschool pada SMK Nusantara 1 Kotabumi menggunakan metode extreme programming yang meliputi empat tahapan yaitu: (1) planning (perencanaan); (2) design (perancangan); (3) coding (pengkodean); dan (4) testing (pengujian). Desain sistem smartschool menggunakan bahasa pemodelan berorientasi objek yaitu UML (Unified Modeling Language).
Hasil penelitian ini adalah terciptanya model sistem pembelajaran online sehingga interaksi antara guru dan siswa dapat dilakukan kapanpun dan dimanapun untuk meningkatkan kualitas pendidikan dan mempercepat penyampaian informasi kepada siswa dan orang tua siswa tentang perkembangan dan capaian setiap siswa. Hal ini dapat mendukung pembelajaran di sekolah dan menciptakan budaya/lingkungan belajar yang efektif dan efisien serta paperless.
Burladores e Convitati a Napoli tra Sei e Settecento, da Perrucci ad Abri (e oltre)
Authors: Cotticelli Francesco 
Published: November 2020

This essay provides a comparison of select testimonies of the enduring tradition of Convitato di pietra (The Stone Guest) in Central and Southern Italy from the late 17th to the early 19th century. The text by Perrucci, the scenario from the Casamarciano collection, the anonymous revision located in the Italian Castle Archive at the Beinecke Library at Yale, and Abri’s opera tragica (which relies significantly on Perrucci’s setting) testify to the longevity of this plot – as well as of the Spanish repertoire – on the stage, in spite of notable changes, which reveal dramatic transformations in taste and sensitivity on the part of theatre practitioners and the audience.
Djuren i den rurala livsstilsmigrationen
Authors: Peker Gurbet 
Published: November 2020

Animals and Rural Lifestyle Migration

Gurbet Peker

Keywords: Lifestyle migration, rural idyll, animal husbandry, interspecies relationships

This article examines the role of animals and animal husbandry in rural lifestyle migration to the Gotlandic countryside. One area of interest is the significance of animals and animal husbandry as part of migrants’ notions of the rural idyll and the place they seek. The article also describes and analyses animal-related everyday practices and interspecies relationships that are developed between migrants and animals.

The empirical material has been collected using ethnographic methods based on observations and qualitative interviews. The researcher also emerged herself in aspects of the rural lifestyle migration being studied. The informants have all left the city of Stockholm in favour of life in the Gotlandic countryside, where they devote themselves to small-scale animal husbandry and keep sheep, horses, chickens and other animals.

The theoretical foundation is that humans and other animals are in a state of constant becoming-with and, thus, create each other’s lifeworlds. The focus is on analysing everyday practices and how interspecies relationships shape the migrants and their lifestyles. At the same time, the researcher also looks at the way in which discourses affect the migrants’ rural lifestyle migration, both as cultural preconceptions and everyday practices.

The results show that animals and animal husbandry play a central role in the rural idyll and the place that migrants seek. The interspecies relationships are also important for the informants’ socialisation and establishment processes in the Gotlandic countryside. The migrants find their relationships with the animals meaningful and crucial for the established lifestyle. These close everyday relationships lead the informants to renegotiate aspects of their view of animals as well as their view of eating meat. This lifestyle with animals also involves emotional challenges related to slaughter, an aspect of animal husbandry that the migrants find stressful. The interspecies relationships documented in the material are consistently characterised by ambivalence and constant renegotiations. In summary, the article shows that the animals and the animal-related practices are crucial for the lifestyle to which the migrants aspire, the everyday life they establish, as well as for the migration project as a whole.
Odla tillsammans
Authors: Sherfey Paul 
Published: November 2020

Grow Together: Save the World While Building a Meaningful ‘Bee-lationship’
Paul Sherfey

Keywords: insects; interspecies relationships; human-animal studies; community gardens
Collective gardens – in which individuals work collectively to cultivate and care for a common gardening area – have become a growing phenomenon in recent years. At these sites, the cultivation of community is often as important as the cultivation of organic, local produce. However, observation and digital research carried out in the context of a transnational study of such gardens demonstrates that this community is not limited to human participants, but instead also includes other animal species at these sites. The article investigates the relationships cultivated with one such group – insects. How might we understand the interest shown by gardeners in building hotels and cafés, sowing meadows and arranging festivals for insects? Do participants only see insects for their use-value, or is there something more occurring in the relationship they cultivate, and how it is represented and discussed? Beginning with a discussion of the built environment of the studied collective gardens, the article analyses how certain design choices are specifically oriented towards the use and benefit of insects – especially bees. Progressing from physical space to digital space, the empirical discussion then investigates this interest in bees and their welfare further through several paradigmatic examples. In so doing, discourses communicated in manifestos, social media and news interviews are analysed. This is done in order to explore the worldviews from which individuals and groups understand the importance of bees, as well as the backgrounds that influence their actions and the fantasies for the future that provide a focal point towards which to orient their efforts. Finally, I contrast the discourses about bees with the lack of similar discourse about another group of insects which are readily observable at many sites – wasps. I discuss how differing cultural heritages related to each affect how they are valued and reflect on the possibilities available to us as humans to see ourselves and our future as being dependent on one species, while being comparably indifferent to the presence and important contributions of the other.
KÜLTÜREL DEĞERLERE DUYARLI PEDAGOJİNİN TEMEL EĞİTİME YANSIMALARI
Authors: KARATAŞ Kasım 
Published: November 2020

Bu araştırmada temel eğitim paydaşlarından sınıf öğretmen adaylarının kültürel değerlere duyarlı pedagojinin öğretmen ve öğrenciye yansımaları bakımından görüşleri incelenmiştir. Araştırma deseni olarak nitel araştırma desenlerinden fenomenolojik desen tercih edilmiştir. Araştırma katılımcıları, Türkiye’nin coğrafi olarak farklı bölgelerinde yer alan 4 farklı üniversitenin sınıf öğretmenliği lisans programında öğrenim gören 4’ü erkek 5’i kadın olmak üzere toplam 9 son sınıf öğrencisidir. Veriler yarı-yaplandırılmış görüşme tekniğiyle toplanmıştır. Verilerin analizinde betimsel analiz yöntemi kullanılmış ve veriler iki ayrı tema halinde kategorize edilmiştir. Araştırmadan elde edilen bulgularda kültürel değerlere duyarlı pedagojinin sınıf öğretmenine yansımaları; kültürel uyumunun hızlı olmasına katkı, okula aidiyetinin gelişmesi, mesleki verimliliğinin artması ve güçlü bir öğretim becerisinin gelişmesi şeklindedir. Öğrenciye yansıması ise öğretim sürecine hızlı uyum, okula aidiyeti güçlendirme ve akademik başarısının artması biçimindedir. Sonuç olarak genel anlamda, kültürel değerlere duyarlı pedagojinin hem öğrenci hem sınıf öğretmenine birçok açıdan olumlu yansımaları bulunmaktadır.
Simulação da produção utilizando técnica de dinâmica de sistemas em uma indústria de vidro: estudo de caso em uma processadora de vidro
Authors: Gallegos Raphael Augusto 
Published: November 2020

As empresas cada vez mais buscam por melhorias em seus processos produtivos. A identificação de gargalos ou perdas em processos produtivos é muitas vezes complexo para ser identificado ou solucionado sem ajuda de softwares de simulação. Os processos muitas vezes não são lineares, o que dificulta o gestor a trabalhar com formas convencionais de Estudos de Tempo, Balanceamento de Linha, Balanceamento de Fluxo ou Carga, ou qualquer outra técnica que ele não possa utilizar softwares para simulação. A simulação é um processo de criar e experimentar um sistema por meio de modelos matemáticos. O sistema é composto por entradas (imputs) e saídas (outputs) e as mesmas oferecem um resultado para alguma finalidade. O presente artigo apresenta um estudo de caso para uma indústria do ramo vidreiro, utilizando técnicas de simulação por meio da Dinâmica de Sistemas. Foram simulados 07 cenários que contemplam o aumento gradual na produtividade de cada setor. Dentre todos os cenários analisados o que apresentou melhor resultado para produção no setor do Forno, foi o último cenário. Esse aumento foi de 9,22% com utilização da mesma mão de obra e dentro do horário de trabalho da organização que é de oito horas diárias.