bluuebunny/crossref_metadata_2025_split huggingface dataset:
SURGICAL TREATMENT OF CAROTID STENOSIS IN PATIENTS WITH CORONARY HEAR+T DISEASE IN ORDER TO PREVENT ISCHEMIC STROKE
Authors: Pulyaeva I. S. , Prasol V. A. 
Published: July 2020

Summary. Goal. To analyze the results of surgical treatment of carotid stenosis in patients with coronary heart disease in order to prevent ischemic stroke.
Materials and methods. The analysis included 18 patients treated in the SI «V. T. Zaitseva IGUS of NAMNU» from 2017 to 2019 in combined atherosclerotic lesions of the coronary and carotid arteries which evaluated the reserve brain.
Results and discussion. All patients with two-stage treatment of the first and second groups were discharged in a stable state, one had a clinic of transient ischemic attack in the postoperative period.
Conclusions. Simultaneous operations are advisable in patients with a reduced reserve of both coronary and cerebral circulation. The risk of developing cerebral and cardiac postoperative complications is comparable with the results of phased operations, reducing the length of hospital stay of the patient. The results of the hypoxic test serve as an additional criterion for the decision to impose an internal intra-arterial shunt. This allows you to reduce the time of the main stage of carotid endarterectomy and to avoid additional possible complications in the early postoperative period.
EPIGENOMIC FACTORS FOR THE DEVELOPMENT OF PERITONEAL ADHESIONS
Authors: Boyko V. V. , Yevtushenko D. O. , Kryvorotko I. V. , Taraban I. A. , Minukhin D. V. , Voskresenska N. M. 
Published: July 2020

Summary. The etiology of the development of adhesive disease — the most common postoperative complication — can be determined by epigenomic disorders related to various links of resistance and immunogenetic control.
Purpose of the study. To study the epigenomic factors in the development of adhesive disease, the immune status of patients operated on in the abdominal cavity was studied. The comparison group included 55 patients with a complicated course of peritoneal commissural disease, the main group consisted of 59 patients operated on on the abdominal organs on the background of peritoneal commissural disease, the course of which was asymptomatic.
Results and its discussion. The revealed epigenomic factors associated with the risk of developing adhesive disease: belongs to an increase in the concentration of acute phase proteins - ceruloplasmin, haptoglobin, C-reactive protein, C3 fragment of the complement system proteins, changes in the expression of adhesion molecule genes (CD31 increased by 10 %, CD54 increased to 24.1 % in comparison with the comparison group — 13.25 %).
Conclusions. The results of our studies showed that patients with adhesive disease have a wide range of epigenome trigger factors. Epigenomic factors associated with the risk of developing adhesive disease include an increase in the concentration of acute phase proteins - ceruloplasmin, haptoglobin, C-reactive protein, C3 fragment of the complement system proteins, changes in the expression of adhesion molecule genes (CD31 increased by 10 %, CD54 increased to 24, 1 % compared with the comparison group - 13.25 %)
THE USE OF ENDOTHERMICTRE AT MENT OF THE MOUTH OF THE LARGE SUBCUTANEOUS VEIN IN PATIENTS IN THE ACUTE PERIOD OF VARICOTROMBOPHLEBITIS
Authors: Prasol V. A. , Myasoyedov K. V. , Guyvan I. V. 
Published: July 2020

Summary. One of the most common complications of varicose veins is lower varicotrombophlebitis, which occurs in 30-59 % of cases and is an em bolo genic risk.
Aim. The aim of our study is to evaluate the effectiveness of using the method of endothermic treatment of the mouth of a large subcutaneous vein in patients in the acute period of varicotrombophlebitis.
Materials and methods of research. The data of 58 patients treated for acute varicotrombophlebitis in State Institution “Institute of Generaland Emergency Surgery”. V. T. Zaitseva NAMS of Ukraine”, Kharkov in 2018-2020.
Research results. With ultra sound control in the main group on the 1st post operative day in 100 % of cases, obliteration of the proximal segment of the large subcutaneous veins with the saphenofemoral mouth. After 1 month on ultrasound in the comparison group complete recanalization o VPV trunk, and in the comparison group obliteration of the proximal segment of the VPV in the p/3 thighs, distally was noted recanalization of the VPV.
Conclusions. We consider endothermic treatment of a large saphenous vein in patients with acute varicotrombophlebitis to avoid complications such as deep vein thrombosis or pulmonary.
ORGANIZATION OF DIAGNOSTIC AND DYNAMIC OBSERVATION DURING RECONSTRUCTIVE RESTORATION OF GUNSHIRTING SOFT TISSUES
Authors: Khomenko I. P. , Tsema Ye. V. , Gumenuk К. V. , Tertyshnyi S. V. , Shapovalov V. Yu. 
Published: July 2020

Summary. Damage to the soft tissues of the human body is found both in peacetime and during the war, but the firearms nature has become relevant for Ukraine. Despite the experience gained surgery from previous wars in the treatment of gunshot injuries, there is still no generally accepted diagnostic scheme and classification for reconstructive closure of such specific injuries.
The aim. Demonstrate the features of various methods for diagnosing gunshot wounds of soft tissues proposed for reconstruction of a damaged area.
Results. In order to improve the quality of surgical care at the stages of medical evacuation, it is always necessary to carry out diagnostic procedures and treatment together. Sometimes it is impossible to implement medical care — it is on the front line, sometimes there is a lack of material resources — in the CDL, but it must be understood that the amount of diagnosis and treatment of a gunshot wound with soft tissue damage is always a difficult process.
Conclusions. A multimodal approach to diagnostics and dynamic observation in the reconstruction of soft tissue gunshot injury not only restores the integrity of the damaged anatomical structure but also increases the percentage of functional capacity.
COMPARISON OF TREATMENT OF INTRAABDOMINAL POST-OPERATIVE ABSCESSES WITH THE LAPAROTOMIC AND MINI-INVASIVE INVASIVE ACCESS
Authors: Boyko V. V. , Riga A. S. , Krasnoyaruzhsky A. G. , Myroshnichenko D. O. , Tymchenko M. E. 
Published: July 2020

Summary. The aim of the work was to compare the results of surgical treatment of patients for postoperative abdominal abscesses using different tactics.
Materials and methods. The study included data from 63 patients with postoperative abdominal abscesses. Laparotomy access and use of percutaneous puncture / drainage were compared. Kaplan-Meier survival analysis was used to compare hospitalization duration.
Results. Laparotomic access was performed according to classical methods. After the application of general anesthesia and treatment of the surgical field was performed opening the anterior abdominal wall. The abscess was opened and the contents were aspirated, after treatment of the cavity site with aqueous solutions of antiseptics, the wound was closed and the drainage system was established. Further stages of treatment of intra-abdominal abscess after routine surgery were: aspiration of abscess in the postoperative period through established drainage; diagnostic control of abscess resolution; effective antimicrobial and detoxification therapy. Percutaneous puncture / abscess drainage was performed under ultrasound control using special puncture needles of size F8 - F12. The needle or drainage stlet-catheter was inserted into the abscess cavity, followed by aspiration of the abscess contents and leaving the drainage system. Kaplan-Maier has reduced hospitalizations in patients who have used mini-invasive technologies.
Conclusions. Treatment of postoperative abdominal abscesses involves a surgical approach. Patients with postoperative abscesses who underwent laparotomy access were likely to have an increased total hospitalization duration of 5 days compared with the use of mini-invasive technologies.
THE USE OF CYTOLOGICAL STUDIES TO DETERMINE THE READINESS OF BURN WOUNDS FOR AUTODERMOPLASTY
Authors: Kravtsov O. V. , Shapoval O. V. , Kozin Yu. I. , Isaev Yu. I. , Tsogoev A. A. , Kurbanov T. A. , Beresnyev S. A. , Gopko A. O. 
Published: July 2020

Summary. For an objective assessment of the readiness of burn wounds for autodermoplasty, a cytological technique was used, which allowed to improve the healing of skin flaps, the number of surgical interventions and the treatment time of patients were reduced.
Objective. To improve the results of skin grafting in connection with the use of an objective cytological method for studying the wound process, which allows you to determine the readiness of the wound bed for autodermoplasty.
Materials and methods. In 2019, 29 victims of the main group with deep burns, the cytological method of studying wound prints was used, the comparison group consisted of 32 patients with burns of the same depth and area in which indications for autodermoplasty were determined based on visual criteria.
The results of the study and their discussion. The goal of local preoperative treatment was to achieve an inflammatory-regenerative type of cytograms with a significant decrease in leukocytes, degenerative-destructive forms of neutrophils and the number of bacterial cells. At the same time, the number of polyblasts, macrophages and fibroblasts increased significantly, and there was also a tendency to increase the percentage of lymphocytes. In the main group, autodermoplasty operations were performed only when the indicated type of cytograms was achieved, which allowed to improve the percentage of engraftment of skin flaps, reduce the number of surgical interventions and the treatment time.
Conclusion. For the prognostic assessment of the readiness of deep burns for skin grafting, the cytological method of wound prints was applied. Determination of regenerative types of wound prints gives rise to autodermoplasty.
ETHIOPATHOGENETIC BIOMARKERS FOR THE FORMATION OF HEPATOSPLENOMEGAL SYNDROME AND THE CHOICE OF TREATMENT OF PATIENTS WITH ESOPHAGEAL PHLEBECTASIS BLEEDING
Authors: Klimova O. M. , Sushkov S. V. , Kordon T. I. , Drozdova L. A. , Smachilo R. M. , Lazirsky V. A. , Bychenko K. O. 
Published: July 2020

Summary. A range of specific biomarkers to evaluate the severity of the condition, the choice of tactics, effectiveness and prognosis of treatment are used.
Goal. Evaluation of biomarkers characterizing the etiopathogenetic disorders in hepatosplenomegaly syndrome complicated by recurrent bleeding from esophageal phlebectasis to select individual treatment tactics.
Materials and methods. The digestive function of phagocytes is investigated, the concentration of opsonizing, membranotropic cytotoxic factors and the degree of endogenous intoxication in 3 groups of patients with different etiological factors of hepatosplenomegaly, complicated by bleeding are evaluated.
Results. The presence of specific trigger factors (viral hepatitis, herpes viruses, hereditary-related disorders of lysosomal enzymes) made it possible to classify patients into three groups. In the first group of patients with viral hepatitis B and C the induction of phagocytic activity of neutrophils, a significant increase in lymphocytotoxicity on the background of disorders of protein and lipid metabolism showed. In the second group of patients with the presence of herpes group viruses and autoimmune component an imbalance of opsonizing factors revealed, in particular proteins of the complement system, which caused impaired clearance of low molecular weight immune complexes and products of their degradation. In the third group of patients with hepatitis a significant decrease in the activity of lysosomal enzymes of phagocytic cells are found. The identified pathogenetic biomarkers indicate the presence in this group of patients with congenital enzymopathy characteristic of accumulation diseases. For patients with a pronounced manifestation of intercellular interactions disorders, as an effective alternative to liver transplantation the use of transfusions of mesenchymal stem cells, which are capable of trans differentiation under the influence of mediator microenvironment factors may be.
<p><strong>CONTRIBUTION TO THE KNOWLEDGE ON CICADOMORPHA</strong><strong> </strong><strong>(HEMIPTERA: AUCHENORRHYNCHA) OF MONTENEGRO</strong><strong></strong></p>
Authors: Radović Marina , Pešić Vladimir 
Published: July 2020

In the framework of a master thesis of the first author we conducted the field studies on leafhoppers and planthoppers of Montenegro. In total 3541 specimens belonging to 73 species from 52 genera of leafhoppers and planthoppers were collected. Aphrophora salicina (Goeze, 1778), Philaenus signatus (Melichar, 1896), Idiodonus cruentatus (Panzer, 1799) and Hesium domino (Reuter, 1880) are new for fauna of Montenegro.
Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 Pivotal Studies
Authors: Kiltz Uta , Wei James Cheng-Chung , van der Heijde Désirée , van den Bosch Filip , Walsh Jessica A. , Boonen Annelies , Gensler Lianne S. , Hunter Theresa , Carlier Hilde , Dong Yan , Li Xiaoqi , Bolce Rebecca , Strand Vibeke , Braun Juergen 
Published: July 2020

Objective.This study evaluated the effect of ixekizumab (IXE) on self-reported functioning and health in patients with radiographic axial spondyloarthritis (r-axSpA) who were either biological disease-modifying antirheumatic drug (bDMARD)–naïve or failed at least 1 tumor necrosis factor inhibitor (TNFi).Methods.In 2 multicenter, randomized, double-blind, placebo-controlled, and active-controlled (bDMARD-naïve only) trials, patients with r-axSpA were randomly assigned to receive 80 mg of IXE [every 2 weeks (Q2W) or every 4 weeks (Q4W)], placebo (PBO), or adalimumab (ADA; bDMARD-naïve only). After 16 weeks, patients who received PBO or ADA were rerandomized to receive IXE (Q2W or Q4W) up to Week 52. Functioning and health were measured by the generic 36-item Short Form Health Survey (SF-36) and the disease-specific Assessment of Spondyloarthritis international Society Health Index (ASAS HI). Societal health utility was assessed by the 5-level EuroQol-5 Dimension (EQ-5D-5L).Results.At Week 16, both doses of IXE in bDMARD-naïve and TNFi-experienced patients resulted in larger improvement in SF-36, ASAS HI, and EQ-5D-5L versus placebo. For SF-36, the largest improvements were seen for the domains of bodily pain, physical function, and role physical. A larger proportion of patients reaching improvement in ASAS HI ≥ 3 as well as an achievement of ASAS HI good health status was reported in patients treated with IXE. Improvements were maintained through Week 52.Conclusion.IXE significantly improved functioning and health as assessed by both generic and disease-specific measures, as well as societal health utility values in patients with r-axSpA, as measured by SF-36, ASAS HI, and EQ-5D-5L at Week 16, and improvements were sustained through 52 weeks.
Généalogie, héraldique et filiation en France au XVII e siècle
Authors: Nassiet Michel 
Published: July 2020

Cet article passe en revue les types de généalogies pratiquées au xvii e siècle ainsi que les fonctions sociales qui les motivaient. La généalogie patrilinéaire descendante, qui était pratiquée dès la fin du Moyen Âge, mais oralement, est restée en France pendant cinq siècles le moyen de prouver la noblesse. Par ailleurs, des recherches cognatiques étaient nécessaires dans diverses situations sociales, notamment, en cas de succession collatérale, pour identifier le plus proche consanguin. La généalogie cognatique ascendante, quant à elle, est venue à la mode en France au début du xvii e siècle. À ces pratiques de la généalogie correspondent étroitement l’héraldique et ses évolutions. C’est seulement en tenant compte de cette diversité qu’il est possible de questionner ces productions pour discuter de la nature de la filiation dans la noblesse, ce qui exige de la penser avec souplesse.
Filiations familiales et spirituelles dans les « Vies » religieuses féminines (France, XVII e siècle)
Authors: Duyck Clément 
Published: July 2020

Les personnages des « Vies » religieuses féminines du xvii e siècle apparaissent tributaires de deux origines, familiale et spirituelle. Examinant la thèse de la continuité providentielle qui ferait de ces Vies, héritières des anciennes hagiographies, des parcours narratifs écrits d’avance (Certeau, Le Brun), cet article montre pour sa part combien la rupture avec le premier type de filiation est constitutive du second. Cette rupture assure en effet dans le récit la bascule d’une existence déduite du passé d’une généalogie familiale vers une existence capable de produire de nouvelles filiations, à travers un héritage spirituel appelé à se refonder pour se transmettre au sein d’une institution religieuse.
Zebrafish phd3 Negatively Regulates Antiviral Responses via Suppression of Irf7 Transactivity Independent of Its Prolyl Hydroxylase Activity
Authors: Yu Guangqing , Li Xiong , Zhou Ziwen , Tang Jinhua , Wang Jing , Liu Xing , Fan Sijia , Ouyang Gang , Xiao Wuhan 
Published: July 2020

Abstract
Prolyl hydroxylase domain (PHD)–containing enzyme 3 belongs to the Caenorhabditis elegans gene egl-9 family of prolyl hydroxylases, which has initially been revealed to hydroxylate hypoxia-inducible factor α (HIF-α) and mediate HIF-α degradation. In addition to modulating its target function by hydroxylation, PHD3 has been also shown to influence its binding partners’ function independent of its prolyl hydroxylase activity. In this study, we report that overexpression of zebrafish phd3 suppresses cellular antiviral response. Moreover, disruption of phd3 in zebrafish increases the survival rate upon spring viremia of carp virus exposure. Further assays indicate that phd3 interacts with irf7 through the C-terminal IRF association domain of irf7 and diminishes K63-linked ubiquitination of irf7. However, the enzymatic activity of phd3 is not required for phd3 to inhibit irf7 transactivity. This study provides novel insights into phd3 function and sheds new light on the regulation of irf7 in retinoic acid–inducible gene I–like receptor signaling.
L'ATTUALITÀ DELLE SCELTE ISTITUZIONALI, FINANZIARIE E DI POLITICHE DELLE COMUNITÀ EUROPEE PRIMA DEI TRATTATI DI ROMA
Authors: Ziller Jacques 
Published: July 2020

Les traités de Paris instituant la CECA et la CED, ainsi que le projet de statut de la Communauté politique européenne, qui sont antérieurs aux traités de Rome et ne sont pas actuellement en vigueur, constituent la source la plus importante du dispositif institutionnel de l’Union européenne actuelle et méritent donc d’être étudiés à nouveau, y compris en vue de la poursuite de la réforme de l’UE. Il en va de même pour le droit dérivé et les politiques qui en sont issues, principalement la politique industrielle, et la protection des travailleurs et de l’environnement incluses dans le traité CECA. À cet égard, il convient d’accorder une attention particulière aux Mémoires de Jean Monnet.
Use of ICTS for socio-economic development of marginalised communities in rural areas: Proposals for establishment of sectoral Rural Entrepreneurial Networks
Authors: Nyika Geraldine Taponeswa 
Published: July 2020

Information, Communication, Technology and Services (ICTS) is increasingly being used in various fields that include agriculture, education, medicine, tourism and business. However, due to challenges caused by the digital divide and other factors, the use of ICTS and its contribution to socio-economic development is generally more intense in developed countries than in developing countries, and also more in urban areas than in rural areas. This article gives an overview of ICTS, the extent of its adoption in different fields, factors that hinder ICTS driven socio-economic development in developing countries and rural areas, and various possible ways of maximizing potential benefits that marginalised communities can derive from the limited ICTS that is accessible to them.
Keywords: ICTS, development, marginalised, rural, networks
Prioritising employee-organisation relationships in non-profit organisations in Kenya: Antecedents, queries and contradictions
Authors: Gitau Julie Gathoni , Chebii Stella Jerop 
Published: July 2020

Although employees are the most critical of organisation publics, it is unclear whether employee-organisation relationships (EORs) in non-profit organisations (NPOs) in Kenya are prioritised. To investigate this question further, the study explored relationship antecedents in two non-profit organisations. The study was informed by relationship management theory and the symmetrical communication framework. Semi-structured, indepth interviews were carried out among 24 purposively sampled management and nonmanagement employees. The data was manually analysed and requisite a priori and in vivo codes and themes identified. The study findings suggest a lack of understanding about the strategic role of public relations in the organisation. Further, technician oriented PRdepartments mediate the perceptions of and effort expended on internal relationships. Managing employee-organisation relationships was perceived more as a human resource rather than a PR function which precludes more robust forms of PR practice. The researchers recommend a clear demarcation between the public relations and human resource function and to build strategic PR departments that embrace internal relationship management.
Keywords: Relationship management, employee-organisation relationships, public relations, organisation-public relationships, relationship antecedents
Media Power and Nigeria's Consolidating Democracy
Authors: Jatula Victor 
Published: July 2020

In emerging democracies with weak public institutions, low literacy level, deep-seated ethnic rivalry, and history of centralized, authoritarian rule; to what extent does media agenda-setting influence the political process? The press/politics nexus in consolidating democracies is critical to understanding intricate yet overlapping connexion between politics and development in the Third World. This study examined if media-power shape elections and regime outcomes in Nigeria? Using semi-structured interviews (and incorporating News-Game research tool), findings indicate that Nigeria's two-decade-old democracy remains volatile, fragile, and vulnerable. This vulnerability is complicated by long-standing religious, ethno-regional political suspicions; and overburdened with shifting media ecology, particularly social media disinformation and propaganda. These complexities allow a politics of privilege, class, and power that not only ensures its preservation but also insulates the political elite from public outcry and media pressure. In conclusion, evidence indicates that media power exerts limited influence on elections and regime outcomes. The study recommends renewed effort to investigate power.
Keywords: Nigerian politics, agenda-setting, mass media, democracy, underdevelopment