bluuebunny/crossref_metadata_2025_split huggingface dataset:
An integrative influence of saline water irrigation and fertilization on the structure of soil bacterial communities
Authors: Chen L. J. , Li C. S. , Feng Q. , Wei Y. P. , Zhao Y. , Zhu M. , Deo R. C. 
Published: March 2020

AbstractAlthough numerous studies have investigated the individual effects of salinity, irrigation and fertilization on soil microbial communities, relatively less attention has been paid to their combined influences, especially using molecular techniques. Based on the field of orthogonal designed test and deoxyribonucleic acid sequencing technology, the effects of saline water irrigation amount, salinity level of irrigation water and nitrogen (N) fertilizer rate on soil bacterial community structure were investigated. The results showed that the irrigation amount was the most dominant factor in determining the bacterial richness and diversity, followed by the irrigation water salinity and N fertilizer rate. The values of Chao1 estimator, abundance-based coverage estimator and Shannon indices decreased with an increase in irrigation amount while increased and then decreased with an increase in irrigation water salinity and N fertilizer rate. The highest soil bacterial richness and diversity were obtained under the least irrigation amount (25 mm), medium irrigation water salinity (4.75 dS/m) and medium N fertilizer rate (350 kg/ha). However, different bacterial phyla were found to respond distinctively to these three factors: irrigation amount significantly affected the relative abundances of Proteobacteria and Chloroflexi; irrigation water salinity mostly affected the members of Actinobacteria, Gemmatimonadetes and Acidobacteria; and N fertilizer rate mainly influenced the Bacteroidetes' abundance. The results presented here revealed that the assessment of soil microbial processes under combined irrigation and fertilization treatments needed to be more careful as more variable consequences would be established by comparing with the influences based on an individual factor, such as irrigation amount or N fertilizer rate.
Morphological borrowing from English to Norwegian: The enigmatic non-possessive -s
Authors: Andersen Gisle , Graedler Anne-Line 
Published: March 2020

AbstractWith increased lexical influence and general English competence among Norwegian language users, the association of the suffix -swith the category of plural appears to be expanding. This article explores the occurrence and productivity of non-possessive -sin contemporary Norwegian, a feature which incorporates several phenomena. Our aim is to chart the lexico-grammatical categories instantiated by this morpho-phonological segment in light of the previous literature on Anglicisms in Norwegian and on the basis of empirical evidence from present-day language use. The article presents a corpus-based survey of categories where non-possessive -soccurs (i) as the plural marker of Anglicisms, e.g.drinks; (ii) in colloquialisms such asdritings‘dead drunk’ – a combination of a domestic noun and English (or Norwegian) -ing+ non-possessive -sreanalysed into an adjectival stem; (iii) in nouns likeen caps‘a (baseball) cap’, where it has lost its plurality marking function and become part of the lexical stem; and (iv) sporadically as a plurality marker of domestic or non-English words, e.g.temas. The variability in presence vs. absence of -sis further explored in four case studies dedicated to different stages of borrowing.
Competition, production efficiency and yield stability of finger millet and legume additive design intercropping
Authors: Bitew Yayeh , Alemayehu Getachew , Adgo Enyew , Assefa Alemayehu 
Published: March 2020

AbstractCurrently, the unchecked increase in human population results in increased demand for agricultural lands. Growing two or more crops simultaneously is one of the mechanisms to reduce this problem. A field experiment was conducted in northwestern Ethiopia during 2017 and 2018 cropping seasons. Two legume crops [haricot bean (Phaseolus vulgaris) and lupine (Lupinus angustifolius)] were intercropped with finger millet (Eleusine coracana) using two intercrop planting methods (row and mixture) and three finger millet-legume planting ratios (100.0%:75.0%, 100.0%:50.0% and 100.0%:25.0% of the respective recommended seed rate of sole crops). Two sole crop finger millets (planted in rows and broadcast) and two sole legume crops (haricot bean and lupine) were included as checks. The experiment comprised a randomized complete block design with three replications. Results indicated intercropped finger millet and total land output yield from finger millet-haricot bean row intercropping at a 100:50 planting ratio and sole finger millet planted in a row improved better yield stability. Finger millet-haricot bean row intercropping at a 100:50 planting ratio also resulted in higher grain yields of the component crops, area time equivalent ratio (1.34), relative production (38.1%) and economic (314.0%) efficiencies with a relatively lower component crop competitive ratio. Thus, this cropping system offered increased productivity and economic return and is a viable option for increasing household food security.
A Library of Elastic Tensors for Lowermost Mantle Seismic Anisotropy Studies and Comparison With Seismic Observations
Authors: Creasy Neala , Miyagi Lowell , Long Maureen D. 
Published: March 2020

AbstractThe exact mechanism for lowermost mantle seismic anisotropy remains unknown; however, work on the elasticity and deformation of lower mantle materials has constrained a few possible options. The most probable minerals producing anisotropy are bridgmanite, postperovskite, and ferropericlase. While there is an extensive literature on the elasticity and deformation of lower mantle minerals, we create a comprehensive uniform database of D″ anisotropy scenarios. In order to characterize a range of the possible fabrics for D″ anisotropy, we carry out VPSC (visco‐plastic self‐consistent modeling) to predict textures for each proposed mineral and dominant slip system. We numerically deform each mineral under different geometrical scenarios: simple shear, pure shear, and extension. By using published single crystal elasticity values, we produce a library of 336 candidate elastic tensors. We used the elastic tensor library to revisit previously published D″‐associated seismic anisotropy studies for crossing raypaths (Siberia, North America, the Afar region of Africa, and Australia). While we cannot identify a single, unique mechanism that explains all of these data sets, we find that postperovskite (dominant slip on [100](010) or [100](001)) and periclase (dominant slip on {100}<011>) provide the best fit to the observations and suggest reasonable shear directions for each region of interest. Bridgmanite generally provides a poor fit to the observations; however, we cannot completely rule out any particular model. As the number of anisotropy observations for D″ increases, this elastic tensor library will be helpful for observational seismologists in identifying possible mechanisms of anisotropy and shear directions at in the lowermost mantle.
Preterm white matter injury: ultrasound diagnosis and classification
Authors:   eurUS.brain group, Agut Thais , Alarcon Ana , Cabañas Fernando , Bartocci Marco , Martinez-Biarge Miriam , Horsch Sandra 
Published: March 2020

AbstractWhite matter injury (WMI) is the most frequent form of preterm brain injury. Cranial ultrasound (CUS) remains the preferred modality for initial and sequential neuroimaging in preterm infants, and is reliable for the diagnosis of cystic periventricular leukomalacia. Although magnetic resonance imaging is superior to CUS in detecting the diffuse and more subtle forms of WMI that prevail in very premature infants surviving nowadays, recent improvement in the quality of neonatal CUS imaging has broadened the spectrum of preterm white matter abnormalities that can be detected with this technique. We propose a structured CUS assessment of WMI of prematurity that seeks to account for both cystic and non-cystic changes, as well as signs of white matter loss and impaired brain growth and maturation, at or near term equivalent age. This novel assessment system aims to improve disease description in both routine clinical practice and clinical research. Whether this systematic assessment will improve prediction of outcome in preterm infants with WMI still needs to be evaluated in prospective studies.
Deviations in early hippocampus development contribute to visual hallucinations in schizophrenia
Authors: Cachia Arnaud , Cury Claire , Brunelin Jérôme , Plaze Marion , Delmaire Christine , Oppenheim Catherine , Medjkane François , Thomas Pierre , Jardri Renaud 
Published: March 2020

AbstractAuditory hallucinations (AHs) are certainly the most emblematic experiences in schizophrenia, but visual hallucinations (VHs) are also commonly observed in this developmental psychiatric disorder. Notably, several studies have suggested a possible relationship between the clinical variability in hallucinations′ phenomenology and differences in brain development/maturation. In schizophrenia, impairments of the hippocampus, a medial temporal structure involved in mnesic and neuroplastic processes, have been repeatedly associated with hallucinations, particularly in the visual modality. However, the possible neurodevelopmental origin of hippocampal impairments in VHs has never been directly investigated. A classic marker of early atypical hippocampal development is incomplete hippocampal inversion (IHI). In this study, we compared IHI patterns in healthy volunteers, and two subgroups of carefully selected schizophrenia patients experiencing frequent hallucinations: (a) those with pure AHs and (b) those with audio–visual hallucinations (A+VH). We found that VHs were associated with a specific IHI pattern. Schizophrenia patients with A+VH exhibited flatter left hippocampi than patients with pure AHs or healthy controls. This result first confirms that the greater clinical impairment observed in A+VH patients may relate to an increased neurodevelopmental weight in this subpopulation. More importantly, these findings bring crucial hints to better specify the sensitivity period of A+VH-related IHI during early brain development.
Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction
Authors: Sakaue Saori , Hirata Jun , Kanai Masahiro , Suzuki Ken , Akiyama Masato , Lai Too Chun , Arayssi Thurayya , Hammoudeh Mohammed , Al Emadi Samar , Masri Basel K. , Halabi Hussein , Badsha Humeira , Uthman Imad W. , Saxena Richa , Padyukov Leonid , Hirata Makoto , Matsuda Koichi , Murakami Yoshinori , Kamatani Yoichiro , Okada Yukinori 
Published: March 2020

AbstractThe diversity in our genome is crucial to understanding the demographic history of worldwide populations. However, we have yet to know whether subtle genetic differences within a population can be disentangled, or whether they have an impact on complex traits. Here we apply dimensionality reduction methods (PCA,t-SNE, PCA-t-SNE, UMAP, and PCA-UMAP) to biobank-derived genomic data of a Japanese population (n = 169,719). Dimensionality reduction reveals fine-scale population structure, conspicuously differentiating adjacent insular subpopulations. We further enluciate the demographic landscape of these Japanese subpopulations using population genetics analyses. Finally, we perform phenome-wide polygenic risk score (PRS) analyses on 67 complex traits. Differences in PRS between the deconvoluted subpopulations are not always concordant with those in the observed phenotypes, suggesting that the PRS differences might reflect biases from the uncorrected structure, in a trait-dependent manner. This study suggests that such an uncorrected structure can be a potential pitfall in the clinical application of PRS.
The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche
Authors: Ataca Dalya , Aouad Patrick , Constantin Céline , Laszlo Csaba , Beleut Manfred , Shamseddin Marie , Rajaram Renuga Devi , Jeitziner Rachel , Mead Timothy J. , Caikovski Marian , Bucher Philipp , Ambrosini Giovanna , Apte Suneel S. , Brisken Cathrin 
Published: March 2020

AbstractEstrogens and progesterone control breast development and carcinogenesis via their cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How they control the extracellular matrix, important to breast physiology and tumorigenesis, remains unclear. Here we report that both hormones induce the secreted protease Adamts18 in myoepithelial cells by controlling Wnt4 expression with consequent paracrine canonical Wnt signaling activation. Adamts18 is required for stem cell activation, has multiple binding partners in the basement membrane and interacts genetically with the basal membrane-specific proteoglycan, Col18a1, pointing to the basement membrane as part of the stem cell niche. In vitro, ADAMTS18 cleaves fibronectin; in vivo, Adamts18 deletion causes increased collagen deposition during puberty, which results in impaired Hippo signaling and reduced Fgfr2 expression both of which control stem cell function. Thus, Adamts18 links luminal hormone receptor signaling to basement membrane remodeling and stem cell activation.
Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity
Authors: Seo Wooseok , Shimizu Kanako , Kojo Satoshi , Okeke Arinze , Kohwi-Shigematsu Terumi , Fujii Shin-ichiro , Taniuchi Ichiro 
Published: March 2020

AbstractCCL5 is a unique chemokine with distinct stage and cell-type specificities for regulating inflammation, but how these specificities are achieved and how CCL5 modulates immune responses is not well understood. Here we identify two stage-specific enhancers: the proximal enhancer mediates the constitutive CCL5 expression during the steady state, while the distal enhancer located 1.35 Mb from the promoter induces CCL5 expression in activated cells. Both enhancers are antagonized by RUNX/CBFβ complexes, and SATB1 further mediates the long-distance interaction of the distal enhancer with the promoter. Deletion of the proximal enhancer decreases CCL5 expression and augments the cytotoxic activity of tissue-resident T and NK cells, which coincides with reduced melanoma metastasis in mouse models. By contrast, increased CCL5 expression resulting from RUNX3 mutation is associated with more tumor metastasis in the lung. Collectively, our results suggest that RUNX3-mediated CCL5 repression is critical for modulating anti-tumor immunity.
Ionic amplifying circuits inspired by electronics and biology
Authors: Lucas Rachel A. , Lin Chih-Yuan , Baker Lane A. , Siwy Zuzanna S. 
Published: March 2020

AbstractIntegrated circuits are present in all electronic devices, and enable signal amplification, modulation, and relay. Nature uses another type of circuits composed of channels in a cell membrane, which regulate and amplify transport of ions, not electrons and holes as is done in electronic systems. Here we show an abiotic ionic circuit that is inspired by concepts from electronics and biology. The circuit amplifies small ionic signals into ionic outputs, and its operation mimics the electronic Darlington amplifier composed of transistors. The individual transistors are pores equipped with three terminals including a gate that is able to enrich or deplete ions in the pore. The circuits we report function at gate voltages < 1 V, respond to sub-nA gate currents, and offer ion current amplification with a gain up to ~300. Ionic amplifiers are a logical step toward improving chemical and biochemical sensing, separations and amplification, among others.
High-quality photonic entanglement out of a stand-alone silicon chip
Authors: Oser Dorian , Tanzilli Sébastien , Mazeas Florent , Alonso-Ramos Carlos , Le Roux Xavier , Sauder Grégory , Hua Xin , Alibart Oliver , Vivien Laurent , Cassan Éric , Labonté Laurent 
Published: March 2020

AbstractThe fruitful association of quantum and integrated photonics holds the promise to produce, manipulate, and detect quantum states of light using compact and scalable systems. Integrating all the building blocks necessary to produce high-quality photonic entanglement in the telecom-wavelength range out of a single chip remains a major challenge, mainly due to the limited performance of on-chip light rejection filters. We report a stand-alone, telecom-compliant device that integrates, on a single substrate, a nonlinear photon-pair generator and a passive pump-rejection filter. Using standard channel-grid fiber demultiplexers, we demonstrate the first entanglement qualification of such an integrated circuit, showing the highest raw quantum interference visibility for time-energy entangled photons over two telecom-wavelength bands. Genuinely pure, maximally entangled states can therefore be generated thanks to the high-level of noise suppression obtained with the pump filter. These results will certainly further promote the development of more advanced and scalable photonic-integrated quantum systems compliant with telecommunication standards.
A global database of soil nematode abundance and functional group composition
Authors: van den Hoogen Johan , Geisen Stefan , Wall Diana H. , Wardle David A. , Traunspurger Walter , de Goede Ron G. M. , Adams Byron J. , Ahmad Wasim , Ferris Howard , Bardgett Richard D. , Bonkowski Michael , Campos-Herrera Raquel , Cares Juvenil E. , Caruso Tancredi , de Brito Caixeta Larissa , Chen Xiaoyun , Costa Sofia R. , Creamer Rachel , da Cunha e Castro José Mauro , Dam Marie , Djigal Djibril , Escuer Miguel , Griffiths Bryan S. , Gutiérrez Carmen , Hohberg Karin , Kalinkina Daria , Kardol Paul , Kergunteuil Alan , Korthals Gerard , Krashevska Valentyna , Kudrin Alexey A. , Li Qi , Liang Wenju , Magilton Matthew , Marais Mariette , Martín José Antonio Rodríguez , Matveeva Elizaveta , Mayad El Hassan , Mzough E. , Mulder Christian , Mullin Peter , Neilson Roy , Nguyen T. A. Duong , Nielsen Uffe N. , Okada Hiroaki , Rius Juan Emilio Palomares , Pan Kaiwen , Peneva Vlada , Pellissier Loïc , da Silva Julio Carlos Pereira , Pitteloud Camille , Powers Thomas O. , Powers Kirsten , Quist Casper W. , Rasmann Sergio , Moreno Sara Sánchez , Scheu Stefan , Setälä Heikki , Sushchuk Anna , Tiunov Alexei V. , Trap Jean , Vestergård Mette , Villenave Cecile , Waeyenberge Lieven , Wilschut Rutger A. , Wright Daniel G. , Keith Aidan M. , Yang Jiue-in , Schmidt Olaf , Bouharroud R. , Ferji Z. , van der Putten Wim H. , Routh Devin , Crowther Thomas W. 
Published: March 2020

AbstractAs the most abundant animals on earth, nematodes are a dominant component of the soil community. They play critical roles in regulating biogeochemical cycles and vegetation dynamics within and across landscapes and are an indicator of soil biological activity. Here, we present a comprehensive global dataset of soil nematode abundance and functional group composition. This dataset includes 6,825 georeferenced soil samples from all continents and biomes. For geospatial mapping purposes these samples are aggregated into 1,933 unique 1-km pixels, each of which is linked to 73 global environmental covariate data layers. Altogether, this dataset can help to gain insight into the spatial distribution patterns of soil nematode abundance and community composition, and the environmental drivers shaping these patterns.
Generation of a murine SWATH-MS spectral library to quantify more than 11,000 proteins
Authors: Zhong Chuan-Qi , Wu Jianfeng , Qiu Xingfeng , Chen Xi , Xie Changchuan , Han Jiahuai 
Published: March 2020

AbstractTargeted SWATH-MS data analysis is critically dependent on the spectral library. Comprehensive spectral libraries of human or several other organisms have been published, but the extensive spectral library for mouse, a widely used model organism is not available. Here, we present a large murine spectral library covering more than 11,000 proteins and 240,000 proteotypic peptides, which included proteins derived from 9 murine tissue samples and one murine L929 cell line. This resource supports the quantification of 67% of all murine proteins annotated by UniProtKB/Swiss-Prot. Furthermore, we applied the spectral library to SWATH-MS data from murine tissue samples. Data are available via SWATHAtlas (PASS01441).
Comparative genomic analysis and mosquito larvicidal activity of four Bacillus thuringiensis serovar israelensis strains
Authors: Alves Giselly B. , Melo Fernando L. , Oliveira Eugenio E. , Haddi Khalid , Costa Lara T. M. , Dias Marcelo L. , Campos Fabrício S. , Pereira Eliseu J. G. , Corrêa Roberto F. T. , Ascêncio Sergio D. , Santos Gil R. , Smagghe Guy , Ribeiro Bergmann M. , Aguiar Raimundo W. S. 
Published: March 2020

AbstractBacillus thuringiensis serovar israelensis (Bti) is used to control insect vectors of human and animal diseases. In the present study, the toxicity of four strains of Bti, named T0124, T0131, T0137, and T0139, toward Aedes aegypti and Culex quinquefasciatus larvae was analyzed. The T0131 strain showed the highest larvicidal activity against A. aegypti (LC50 = 0.015 µg/ml) and C. quinquefasciatus larvae (LC50 = 0.035 µg/ml) when compared to the other strains. Furthermore, the genomic sequences of the four strains were obtained and compared. These Bti strains had chromosomes sizes of approximately 5.4 Mb with GC contents of ~35% and 5472–5477 putative coding regions. Three small plasmids (5.4, 6.8, and 7.6 kb) and three large plasmids (127, 235, and 359 kb) were found in the extrachromosomal content of all four strains. The SNP-based phylogeny revealed close relationship among isolates from this study and other Bti isolates, and SNPs analysis of the plasmids 127 kb did not reveal any mutations in δ-endotoxins genes. This newly acquired sequence data for these Bti strains may be useful in the search for novel insecticidal toxins to improve existing ones or develop new strategies for the biological control of important insect vectors of human and animal diseases.
Acute Restraint Stress Evokes Anxiety-Like Behavior Mediated by Telencephalic Inactivation and GabAergic Dysfunction in Zebrafish Brains
Authors: Assad Nadyme , Luz Waldo Lucas , Santos-Silva Mateus , Carvalho Tayana , Moraes Suellen , Picanço-Diniz Domingos Luiz Wanderley , Bahia Carlomagno Pacheco , Oliveira Batista Evander de Jesus , da Conceição Passos Adelaide , Oliveira Karen Renata Herculano Matos , Herculano Anderson Manoel 
Published: March 2020

AbstractAcute stress is an important factor in the development of anxiety disorders. Zebrafish are an organism model widely used by studies that aim to describe the events in the brain that control stress-elicited anxiety. The goal of the current study was to evaluate the pattern of cell activation in the telencephalon of adult zebrafish and the role of the GABAergic system on the modulation of anxiety-like behavior evoked by acute restraint stress. Zebrafish that underwent acute restraint stress presented decreased expression of the c-fos protein in their telencephalon as well as a significant decrease in GABA release. The data also supports that decreased GABA levels in zebrafish brains have diminished the activation of GABAA receptors eliciting anxiety-like behavior. Taken together these findings have helped clarify a neurochemical pathway controlling anxiety-like behavior evoked by acute stress in zebrafish while also opening the possibility of new perspective opportunities to use zebrafish as an animal model to test anxyolitic drugs that target the GABAergic system.