bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-cleanable, waterproof, transparent, and flexible Ag networks covered by hydrophobic polytetrafluoroethylene for multi-functional flexible thin film heaters
Authors: Lee Ji-Eun , Kim Han-Ki 
Published: November 2019

AbstractWe demonstrate a self-cleanable, waterproof, highly transparent, and flexible Ag network covered by a very thin transparent polytetrafluoroethylene (PTFE) layer using typical magnetron sputtering for multi-functional flexible thin film heaters used in smart windows. By passivation of the self-assembled Ag network with very thin PTFE films, we fabricated a multi-functional Ag network suitable for flexible thin film heaters. At a PTFE thickness of 10 nm, the Ag network passivated by hydrophobic PTFE layer showed a low sheet resistance of 11.64 Ohm/square, high optical transmittance of 80.20% at a wavelength of 550 nm, and high contact angle of 102.42°. In addition, sputtering of the PTFE layer on the Ag network improved the mechanical flexibility and reliability of the Ag network electrode. The flexible and transparent thin film heater (TTFH) with Ag network electrode covered by PTFE layer showed a saturation temperature of 120 °C at low voltage of 4.5 V and power of 2.45 W, as well as a hydrophobic surface suited for self-cleaning smart windows. These multi-functional performances of TTFH indicate that the Ag network/PTFE film-based flexible TTFH could be used as self-cleanable, waterproof TTFHs for curved smart windows in smart buildings and automobiles.
Identification of high-risk patients for ADR induced by traditional Chinese medicine injection: a nested case-control study
Authors: Jiang Cheng , Shen Jie , Shou Dan , Wang Nani , Jing Jing , Zhang Guodi , Gu Jing , Tian Yunlong , Sun Caihua , He Jiaqi , Ma Jiaqi , Wang Xiaojun , Li Gonghua 
Published: November 2019

AbstractThe adverse drug reaction (ADR) of traditional Chinese medicine injection (TCMI) has become one of the major concerns of public health in China. There are significant advantages for developing methods to improve the use of TCMI in routine clinical practice. The method of predicting TCMI-induced ADR was illustrated using a nested case-control study in 123 cases and 123 controls. The partial least squares regression (PLSR) models, which mapped the influence of basic characteristics and routine examinations to ADR, were established to predict the risk of ADR. The software was devised to provide an easy-to-use tool for clinic application. The effectiveness of the method was evaluated through its application to new patients with 95.7% accuracy of cases and 91.3% accuracy of controls. By using the method, the patients at high-risk could be conveniently, efficiently and economically recognized without any extra financial burden for additional examination. This study provides a novel insight into individualized management of the patients who will use TCMI.
Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum
Authors: Bui Hai T. N. , Niederwieser Igor , Bird Megan J. , Dai Weiwen , Brancucci Nicolas M. B. , Moes Suzette , Jenoe Paul , Lucet Isabelle S. , Doerig Christian , Voss Till S. 
Published: November 2019

AbstractPrevious studies in model eukaryotes have demonstrated that phosphorylation of heterochromatin protein 1 (HP1) is important for dynamically regulating its various functions. However, in the malaria parasitePlasmodium falciparumboth the function of HP1 phosphorylation and the identity of the protein kinases targeting HP1 are still elusive. In order to functionally analyze phosphorylation ofP. falciparumHP1 (PfHP1), we first mapped PfHP1 phosphorylation sites by liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis of native PfHP1, which identified motifs from which potential kinases could be predicted; in particular, several phosphorylated residues were embedded in motifs rich in acidic residues, reminiscent of targets forP. falciparumcasein kinase 2 (PfCK2). Secondly, we tested recombinant PfCK2 and a number of additional protein kinases for their ability to phosphorylate PfHP1 inin vitrokinase assays. These experiments validated our prediction that PfHP1 acts as a substrate for PfCK2. Furthermore, LC-MS/MS analysis showed that PfCK2 phosphorylates three clustered serine residues in an acidic motif within the central hinge region of PfHP1. To study the role of PfHP1 phosphorylation in live parasites we used CRISPR/Cas9-mediated genome editing to generate a number of conditional PfHP1 phosphomutants based on the DiCre/LoxP system. Our studies revealed that neither PfCK2-dependent phosphorylation of PfHP1, nor phosphorylation of the hinge domain in general, affect PfHP1′s ability to localize to heterochromatin, and that PfHP1 phosphorylation in this region is dispensable for the proliferation ofP. falciparumblood stage parasites.
Sex difference in fatigability of knee extensor muscles during sustained low-level contractions
Authors: Akagi Ryota , Sato Shinya , Yoshihara Kana , Ishimatsu Hideki , Ema Ryoichi 
Published: November 2019

AbstractThis study investigated whether the sex difference in fatigability of the knee extensors (KE) is explained by the sex difference in fatigue-induced changes in the shear modulus of one or more muscles of KE in 18 young men and 23 young women. The shear moduli of the resting rectus femoris and medial and lateral vastus muscles (VL) were measured before and after a sustained contraction at 20% peak torque during a maximal voluntary isometric contraction of KE until the endurance limit, in addition to evoked torque and voluntary activation (VA%). The fatigue-induced decrease in maximal muscle strength was more prominent in men than in women. Only the VL shear modulus for men increased after the fatiguing task, and a sex difference was observed in the percentage change in the VL shear modulus before and after the fatiguing task. The fatigue-induced decreased ratio was greater for men than for women in evoked torque, but not in VA%. These results suggest that although peripheral and central fatigue both influenced the fatigue-induced decrease in maximal muscle strength regardless of sex, the sex difference in KE fatigability is explained by that in peripheral fatigue, particularly the degree of peripheral VL fatigue.
Efficient Sn Recovery from SnO2 by Alkane (CxHy=2x+2, 0 ≤ x ≤ 4) Reduction
Authors: An Hyesung , Yoo Mi , Ha Hyunwoo , Choi Hyuk , Kang Eunji , Kim Hyun You 
Published: November 2019

AbstractWe study the mechanism of alkane reduction of SnO2 for efficient low-temperature recovery of Sn from SnO2. Based on thermodynamic simulation results, we comparatively analyze the reduction behavior and the efficiency of SnO2 reduction by H2 and alkanes (CxHy=2x+2, 0 ≤ x ≤ 4). We found that alkanes (n·CxHy) with the higher nx generally complete the reduction of SnO2 (T100) at the lower temperature. Moreover, the T100 of the SnO2 reduction by alkanes (n·CxHy) was decreased from the T100 of pure hydrogen with the same amount of hydrogen atoms (n·Hy). We found that the concentration of a gas phase product mixture, the amount of the produced solid carbon, and the T100 complementary vary as a function of the nx and ny, the total amount of carbon and hydrogen atoms in the reducing gas phase molecules. Our results demonstrate a viability of the low temperature reduction method of SnO2 by alkanes for efficient recovery of Sn from SnO2, which can be applied for Sn recovery from Sn containing industrial wastes or Sn ores with economic value added that is held by the co-produced H2.
The Vitamin D status is associated with serum C-reactive protein and adhesion molecules in patients with renal cell carcinoma
Authors: Xu Shen , Song Jin , Zhang Zhi-Hui , Fu Lin , Gao Lan , Xie Dong-Dong , Yu De-Xin , Xu De-Xiang , Sun Guo-Ping 
Published: November 2019

AbstractLow vitamin D status is associated with an increased risk of renal cell carcinoma (RCC). This study investigated the association of vitamin D status with serum C-reactive protein (CRP) and adhesion molecules among RCC patients. Fifty newly diagnosed RCC patients and 100 age- and sex-matched controls were recruited. As expected, serum 25(OH)D level was lower in RCC patients than in controls. By contrast, serum levels of CRP, an inflammatory molecule, and ICAM, LAMA4 and EpCAM, three adhesion molecules, were higher in RCC patients than in controls. All RCC patients were divided into two groups: H-VitD (>20 ng/ml) or L-VitD (<20 ng/ml). Interestingly, the levels of serum CRP and all adhesion molecules were higher in RCC patients with L-VitD than those with H-VitD. Nuclear vitamin D receptor (VDR) was downregulated and nuclear factor kappa B (NF-κB) was activated in cancerous tissues. The in vitro experiments found that VitD3 suppressed NF-κB activation and adhesion molecules in RCC cells. Moreover, VitD3 suppressed NF-κB through reinforcing physical interaction between VDR and NF-κB p65 subunit in RCC cells. These results provide a mechanistic explanation for the association among low vitamin D status, local inflammation and increased expression of adhesion molecules among RCC patients.
Plant poisoning leads to alpha-synucleinopathy and neuromelanopathy in kangaroos
Authors: Tayebi Mourad , El-Hage Charles M. , Pinczowski Pedro , Whiteley Pam , David Monique , Li Qiao-Xin , Varghese Shiji , Mikhael Meena , Habiba Umma , Harman David , Tatarczuch Liliana , Bogeski Mirjana , Birchall Ian , Ferguson Kirsty , Walker Larry , Masters Colin , Summers Brian A. 
Published: November 2019

AbstractThe pathogenesis of synucleinopathies, common neuropathological lesions normally associated with some human neurodegenerative disorders such as Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy, remains poorly understood. In animals, ingestion of the tryptamine-alkaloid-rich phalaris pastures plants causes a disorder called Phalaris staggers, a neurological syndrome reported in kangaroos. The aim of the study was to characterise the clinical and neuropathological changes associated with spontaneous cases of Phalaris staggers in kangaroos. Gross, histological, ultrastructural and Immunohistochemical studies were performed to demonstrate neuronal accumulation of neuromelanin and aggregated α-synuclein. ELISA and mass spectrometry were used to detect serum-borne α-synuclein and tryptamine alkaloids respectively. We report that neurons in the central and enteric nervous systems of affected kangaroos display extensive accumulation of neuromelanin in the perikaryon without affecting neuronal morphology. Ultrastructural studies confirmed the typical structure of neuromelanin. While we demonstrated strong staining of α-synuclein, restricted to neurons, intracytoplasmic Lewy bodies inclusions were not observed. α-synuclein aggregates levels were shown to be lower in sera of the affected kangaroos compared to unaffected herd mate kangaroos. Finally, mass spectrometry failed to detect the alkaloid toxins in the sera derived from the affected kangaroos. Our preliminary findings warrant further investigation of Phalaris staggers in kangaroos, potentially a valuable large animal model for environmentally-acquired toxic synucleinopathy.
An innovative magnetic state generator using machine learning techniques
Authors: Kwon H. Y. , Kim N. J. , Lee C. K. , Yoon H. G. , Choi J. W. , Won C. 
Published: November 2019

AbstractWe propose a new efficient algorithm to simulate magnetic structures numerically. It contains a generative model using a complex-valued neural network to generate k-space information. The output information is hermitized and transformed into real-space spin configurations through an inverse fast Fourier transform. The Adam version of stochastic gradient descent is used to minimize the magnetic energy, which is the cost of our algorithm. The algorithm provides the proper ground spin configurations with outstanding performance. In model cases, the algorithm was successfully applied to solve the spin configurations of magnetic chiral structures. The results also showed that a magnetic long-range order could be obtained regardless of the total simulation system size.
Isolation and characterization of cellulose nanocrystals from jackfruit peel
Authors: Trilokesh C. , Uppuluri Kiran Babu 
Published: November 2019

AbstractIn the present work, sustainable nanomaterials, cellulose, and spherical cellulose nanocrystals (SCNCs) were isolated from the non-edible parts of jackfruit (Artocarpus heterophyllus). Of the three different methods tested, sodium chlorite treatment produced the highest yield of cellulose, 20.08 ± 0.05% w/w (dry weight). Peaks observed in CP/MAS 13C NMR spectrum and FTIR frequencies revealed the presence of α-cellulose and absence of other biomass fractions like hemicellulose and lignin. XRD analysis showed a high crystallinity of 83.42%. An appearance of a sharp endothermal peak at 323 °C in DSC and decomposition patterns between 310–420 °C of TGA confirms the presence of cellulose. Further, Sulphuric acid hydrolysis was employed to produce SCNCs and examined by TEM for the morphology and by HPLC for the presence of glucose.
Bifurcation of self-assembly pathways to sheet or cage controlled by kinetic template effect
Authors: Foianesi-Takeshige Leonardo Hayato , Takahashi Satoshi , Tateishi Tomoki , Sekine Ryosuke , Okazawa Atsushi , Zhu Wenchao , Kojima Tatsuo , Harano Koji , Nakamura Eiichi , Sato Hirofumi , Hiraoka Shuichi 
Published: November 2019

AbstractThe template effect is a key feature to control the arrangement of building blocks in assemblies, but its kinetic nature remains elusive compared to the thermodynamic aspects, with the exception of very simple reactions. Here we report a kinetic template effect in a self-assembled cage composed of flexible ditopic ligands and Pd(II) ions. Without template anion, a micrometer-sized sheet is kinetically trapped (off-pathway), which is converted into the thermodynamically most stable cage by the template anion. When the template anion is present from the start, the cage is selectively produced by the preferential cyclization of a dinuclear intermediate (on-pathway). Quantitative and numerical analyses of the self-assembly of the cage on the on-pathway revealed that the accelerating effect of the template is stronger for the early stage reactions of the self-assembly than for the final cage formation step itself, indicating the kinetic template effect.
Determination of whole-body tumour burden on [68Ga]PSMA-11 PET/CT for response assessment of [177Lu]PSMA-617 radioligand therapy: a retrospective analysis of serum PSA level and imaging derived parameters before and after two cycles of therapy
Authors: Michalski Kerstin , Mix Michael , Meyer Philipp T. , Ruf Juri 
Published: November 2019

Abstract
Aim In patients with metastasized castration-resistant prostate cancer a reliable imaging-based therapy response assessment in addition to PSA kinetics is desirable. Recently, measurements of whole-body tumour burden by [68Ga]PSMA-11 PET/CT have been reported for response assessment in oligometastasic patients. The present study investigated the association of PSMA PET derived parameters and serum PSA level before and after [177Lu]PSMA-617 radioligand therapy (RLT).
Methods This retrospective study assessed whole-body PSMA tumour volume (PSMA-TV) in 10 patients with multifocal to diffuse metastases before and after 2 cycles of RLT using volume of interest (VOI) analysis. A standardized uptake value (SUV) threshold-based approach was used to semi-automatically delineate all voxels with a SUV ≥ 2.0 g/ml using the software ROVER® (ABX Radeberg, Germany). Voxels with physiological tracer uptake (e. g. kidneys) were excluded manually. Correlations between PSMA-TV and serum PSA level before and after two cycles of RLT as well as changes thereof (ΔPSMA-TV and ΔPSA, respectively) were calculated.
Results Changes of ΔPSMA-TV and ΔPSA were concordant in 7 of 10 patients. Whereas a good correlation was found between PSMA-TV and PSA before RLT (ρ = 0.81, p = 0.0049), this correlation was attenuated after RLT (ρ = 0.64, p = 0.0479). Consequently, no association was found between ΔPSMA-TV and ΔPSA (ρ = 0.39, p = 0.26).
Conclusion The attenuation of the correlation of PSA and PSMA-TV after RLT suggests that in patients with advanced disease the comparison of imaging based parameters such as PSMA-TV and PSA level might be useful for an adequate monitoring of treatment response.
Étale monodromy and rational equivalence for -cycles on cubic hypersurfaces in
Authors: Banerjee K. , Guletskiĭ V. 
Published: November 2019

AbstractLetbe an uncountable algebraically closed field of characteristic, and letbe a smooth projective connected variety of dimension, embedded intoover. Letbe a hyperplane section of, and letandbe the groups of algebraically trivial algebraic cycles of codimensionandmodulo rational equivalence onand, respectively. Assume that, wheneveris smooth, the groupis regularly parametrized by an abelian varietyand coincides with the subgroup of degreeclasses in the Chow group. We prove that the kernel of the push-forward homomorphism fromtois the union of a countable collection of shifts of a certain abelian subvarietyinside. For a very general hyperplane sectioneitherorcoincides with an abelian subvarietyinwhose tangent space is the group of vanishing cycles. Then we apply these general results to sections of a smooth cubic fourfold in.Bibliography: 33 titles.
The statistical properties of 3D Klein polyhedra
Authors: Illarionov A. A. 
Published: November 2019

Abstract
Let

be a rank-

lattice in

. The convex hulls of the nonzero lattice points lying in orthants are called the Klein polyhedra of

. This construction was introduced by Klein in 1895, in connection with generalizing the classical continued-fraction algorithm to the multidimensional case. Arnold stated a number of problems on the statistical and geometric properties of Klein polyhedra. In two dimensions the corresponding results follow from the theory of continued fractions. An asymptotic formula for the mean value of the

-vectors (the numbers of facets, edges and vertices) of 3D Klein polyhedra is derived. This mean value is taken over the Klein polyhedra of integer 3D lattices with determinants in

, where

is an increasing parameter.
Bibliography: 27 titles.
Determination of borders between objects on satellite images using a two-proof doubly stochastic filtration
Authors: Andriyanov N A , Dementyiev V E 
Published: November 2019

Abstract
The text deals with the possibility of using a random process of the algorithm based on the two-pass application of the Kalman filter modification to determine the instant of disorder. A technique is proposed for generalizing this algorithm to the case of processing a random process with slowly varying statistical and correlation properties based on the application of a doubly stochastic filter. The consistency of the approach for determining the borders between objects on two-dimensional digital images is shown.
Performance evaluation of 4-stroke gasoline engine using Bio fuel (Ethanol)
Authors: Rafeh A , Obaidullah K , Masih A , Rehman A 
Published: November 2019

Abstract
The article examines the performance of a 4-stroke gasoline engine using Bio-fuel (Ethanol). The research work was carried out on a SOLTEQ engine test bed available in university in Thermodynamics laboratory. In this study an ordinary gasoline engine was fixed on test bed. Several modifications to external parts of the engine were made to fix it on the bed such as base frame, suction port, exhaust port and oil temperature indicators. To asses engine performance the experiment setting used gasoline with 5 different blends of ethanol such as E0 (100% gasoline), E5 (95% gasoline, 5% ethanol), E10 (90% gasoline, 10% ethanol), E15 (85% gasoline, 15% ethanol) and E20 (80% gasoline, 20% ethanol). While the engine performance was evaluated at operating parameter called wide open throttle (WOT). Different charts were established to compare results. The results obtained from analysis showed significant deviations in performance curves at different fuel grades. These results were quite useful especially for utilizing ethanol additives with gasoline in ordinary gasoline engines.
Adaptive vibration absorbing method of torsional vibrations for processing equipment
Authors: Bashmur K A , Petrovsky E A , Mazurov I A , Bukhtoyarov V V , Tynchenko S V , Gorodov A A 
Published: November 2019

Abstract
This article describes issues relating to monitoring vibrations affecting the processing equipment. Especially, the problem of negative influence from the increased vibration background in well drilling, where the issue is the most acute, is being described. The urgency of creating methods to monitor vibration condition, due to which it becomes possible to design reliable and efficient structures with the required characteristics and purpose, is shown. Particular attention is paid to passive methods for monitoring torsional vibrations of pipe columns. In this case, the developed method for monitoring the vibration condition of torsional vibrations is presented, and its effectiveness is shown. In addition, a new device for monitoring torsional vibrations to the developed method, which is distinguished by its simplicity as well as high potential of reliability and efficiency, is shown.
Architecture, algorithmic support and software development of aviation synthetic vision system for perspective transport civil aircraft
Authors: Neretin E S , Dyachenko S A 
Published: November 2019

Abstract
The paper considers the aviation onboard synthetic vision system that generates and outputs a three-dimensional (3D) external environment images to the cockpit multifunctional displays (MFD). Particularly, the system architecture, algorithmic support and software are designed. The synthesized images present 3D earth surface areas with high informativity in the real time scale. The example of generated 3D models of real geographic objects is provided.
Development of human gingiva phantom material for minimally invasive robotic-assisted surgery
Authors: Buinov M A , Vorotnikov A A , Klimov D D , Poduraev Y V 
Published: November 2019

Abstract
The article describes the technological process of manufacturing the material for the phantom of human gingiva for subsequent use as a part of a prototype of a robotic system for laser maxillofacial surgery. The prototype of the experimental setup is presented, which allows automating the process of manufacturing the material for this phantom. A preliminary comparison of cuts on the phantom material of gingiva with the biological material of a pig gingiva was made. It has been experimentally proven that the material is well suited for creating gingiva phantoms with complex geometric surface shapes in ways similar to the molding of plastics into silicone molds.
Assurance of complex pressure control system operability in high-temperature media
Authors: Terasmes K S , Petrovsky E A , Bashmur K A , Tynchenko S V , Bukhtoyarov V V , Shepeta N A 
Published: November 2019

Abstract
For the purpose of control and overpressure protection in pipeline systems of power industry and pressure vessels, indirect-action valves consisting of a main valve and a pilot valve are often used. Such devices are characterized by smaller reliability due to complication of their structure depending on operability of these two valves. A pilot valve controlling the whole safety system is the weakest element of the system. It is especially typical of machines operated in severe conditions, since life of sensing elements quickly decreases during work with high-temperature and polluted media. The authors considered the ways for improving reliability of pressure control systems operated in severe conditions by redundancy of the sensing element of the valve with a system equipped with a metal bellows. The authors analyzed reliability of initial systems and redundant systems at various operating temperatures.