bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative Expression Analysis of Circulating miRNAs Reveals Significant Association with Cardiovascular Pathogenesis in Women
Authors: Lakkireddy Chandrakala , Rout Siddharth , Ahmed Shaik Iqbal , Owaisi Nooruddin , Bardia Avinash , Raju Nagarapu , Vishwakarma Sandeep Kumar , Khan Aleem Ahmed 
Published: February 2020

Abstract
Background Cardiovascular disease (CVD) represents a complex pathophysiological condition with continuous increasing mortality and poor treatment outcome. Troponin is the only standard biochemical indication of CVD, which fails to exactly determine the diagnostic and prognostic indications of CVD. Circulating microribonucleic acids (miRNAs) represent crucial molecular targets to determine the pathophysiology of CVD. Hence, in the present study quantitative estimation of three miRNAs (miRNA-133, miRNA-155, and miRNA-222) targeting different pathways of CVD pathogenesis has been performed to find their role.
Methods and Materials A total of 50 female subjects including 25 CVD patients and 25 controls with age range of 18 to 65 years were included in this study. The extraction of circulating miRNAs was done in all the serum samples separated through centrifugation. Relative expression of all three miRNAs was performed using SYBR green–based real-time polymerase chain reaction (RT-PCR) in comparison to internal control.
Results Significantly upregulated expression levels were observed for miRNA-133 and miRNA-222 in CVD women patients as compared with control subjects. Age-wise analysis revealed highly upregulated expression of miRNA-133 in patients having age group <45 years. While comparing with troponin levels, miRNA-222 was found significantly upregulated in patients having troponin levels <250 ng/L whereas miRNA-133 was found significantly higher in >250 ng/L troponin group.
Conclusion Circulating miRNAs specifically miRNA-133 and miRNA-222 have essential role in pathogenesis of CVD in women patients.
Treatable Movement Disorders of Infancy and Early Childhood
Authors: Aravamuthan Bhooma R. , Pearson Toni S. 
Published: February 2020

AbstractMovement disorders in childhood can be difficult to diagnose early. Disease processes present variably and can mimic each other. It is particularly important to remain vigilant for the subset of these movement disorders that are treatable. These disorders can be managed with (1) treatments specific to the disease that substantially reduce symptoms; (2) treatments that can prevent progression; (3) treatments that can hasten recovery; or (4) surveillance and management of the associated, sometimes life-threatening, comorbidities. Here, we present a practical and phenomenology-oriented framework for diagnosing and managing these treatable movement disorders of infancy and early childhood.
INFLUENCE OF THE TOTAL ANTIOXIDANT CONTENT OF SALIVA ON DENTAL CARIES.
Authors: Shetty A. Veena , Kumari Suchetha , A. Geethashri , N. Sneha ,   Darshana
Published: February 2020

Abstract
Objective: The aim of the study was to evaluate the Total Antioxidant level in saliva of caries patients with and without smoking habit.
Methods: A total of 80 individuals were included in the study. Unstimulated saliva was colleced. Samples of smoking and non smoking caries patients showing only Streptococcus mutans growth were analysed for Total Antioxidant level and smokers and nonsmokeres without any caries were considered as control groups. Caries isolates were confirmed as Streptococcus mutans by grams staining and biochemical tests. Total Antioxidant level was determined by spectrophotometric method.
Result: Non smokers with caries showed significantly(P <0.0001) higher TAC level to Smokers with caries. Smokers without caries showed
significantly (P=0.0005)lower level of antioxidants than nonsmokers without caries.
Conclusion: This invasive study shows that smoke adversely effects the Total Antioxidant Level in caries patients.
NECROBIOTIC XANTHOGRANULOMA PRESENTING AS A CLINICAL VARIANT WITHOUT PARAPROTEINEMIA
Authors: Mathias Michelle , Permi Harish S , Shetty Padma , K. Jayaprakash Shetty , Girish B. S. 
Published: February 2020

AbstractNecrobiotic xanthogranuloma is a rare granulomatous disease involving skin and subcutaneous tissues. A 61 year old woman presented with a 5 year history of enlarging plaques around both eyelids.it was associated with diminished vision in both eyes. The lesions are often bilateral,symmetrical and ophthalmologic complications are observed. A histopathological examination showed features of necrobiotic xanthogranuloma. Necrobiotic xanthogranuloma is usually associated with paraproteinemia which was not seen in our case.The pathogenesis remains unclear. Although there is no first line of treatment, reports have shown variable benefits with chemotherapeutic agent and steroids.
Frame-Constructional Verb Classes
Authors: Dux Ryan 
Published: February 2020

While verb classes are a mainstay of linguistic research, the field lacks consensus on precisely what constitutes a verb class. This book presents a novel approach to verb classes, employing a bottom-up, corpus-based methodology and combining key insights from Frame Semantics, Construction Grammar, and Valency Grammar.

On this approach, verb classes are formulated at varying granularity levels to adequately capture both the shared semantic and syntactic properties unifying verbs of a class and the idiosyncratic properties unique to individual verbs. In-depth analyses based on this approach shed light on the interrelations between verbs, frame-semantics, and constructions, and on the semantic richness and network organization of grammatical constructions.
This approach is extended to a comparison of Change and Theft verbs, revealing unexpected lexical and syntactic differences across semantically distinct classes. Finally, a range of contrastive (German–English) analyses demonstrate how verb classes can inform the cross-linguistic comparison of verbs and constructions.
A study of the development of the Chinese correlative comparative construction from the perspective of constructionalization
Authors: Zhan Fangqiong , Traugott Elizabeth Closs 
Published: February 2020

AbstractThe paper addresses the emergence and development of the Chinese correlative comparative construction (CrCC) from the perspective of constructionalization. Most previous historical studies of the CrCC take a grammaticalization approach (e.g.,Long 2013), focusing mainly on morphosyntax alone rather than investigating syntax and semantics in an integrated way. However, the architecture of construction grammar requires approaching linguistic analysis with both form and meaning equally in mind. This approach suggests that what have sometimes been considered to be merely different formal expressions of the CrCC are in fact two different constructions, one correlative, and the other a simple incremental. We identify the critical contexts (seeDiewald & Smirnova 2010) that by hypothesis enabled the constructionalization of the CrCC, and point to the importance of considering network reorganization and multiple sources in the development of the simple incremental construction (see e.g.,Boas 2008;Van de Velde et al. 2013).
Hermione and the Secretary: how gendered task division in introductory physics labs can disrupt equitable learning
Authors: Doucette Danny , Clark Russell , Singh Chandralekha 
Published: February 2020

AbstractPhysics labs provide a unique opportunity for students to grow their physics identity and science identity in general since they provide students with an opportunity to tinker with experiments and analyze data in a low-stakes environment. However, it is important to ensure that all students are benefiting from the labs equally and have a positive growth trajectory. Through interviews and reflexive ethnographic observations, we identify and analyze two common modes of work that may disadvantage female students in introductory physics labs. Students who adopt the Secretary archetype are relegated to recording and analyzing data, and thus may miss out on much of the opportunity to grow their physics and science identities by engaging fully in the experimental work. Meanwhile, students in the Hermione archetype shoulder a disproportionate amount of managerial work, and also may not get an adequate opportunity to engage with different aspects of the experimental work that is essential for helping them develop their physics and science identities. We use a physics identity framework to investigate how students under these modes of work may experience stunted growth in their physics and science identity trajectories in their physics lab course. This stunted growth can then perpetuate and reinforce societal stereotypes and biases about who does physics. Our categorization not only gives a vocabulary to discussions about equity in the physics lab, but may also serve as a useful touchstone for those who seek to center equity in efforts to transform physics instruction.
Noise resilience of variational quantum compiling
Authors: Sharma Kunal , Khatri Sumeet , Cerezo M , Coles Patrick J 
Published: February 2020

Abstract
Variational hybrid quantum-classical algorithms (VHQCAs) are near-term algorithms that leverage classical optimization to minimize a cost function, which is efficiently evaluated on a quantum computer. Recently VHQCAs have been proposed for quantum compiling, where a target unitary U is compiled into a short-depth gate sequence V. In this work, we report on a surprising form of noise resilience for these algorithms. Namely, we find one often learns the correct gate sequence V (i.e. the correct variational parameters) despite various sources of incoherent noise acting during the cost-evaluation circuit. Our main results are rigorous theorems stating that the optimal variational parameters are unaffected by a broad class of noise models, such as measurement noise, gate noise, and Pauli channel noise. Furthermore, our numerical implementations on IBM’s noisy simulator demonstrate resilience when compiling the quantum Fourier transform, Toffoli gate, and W-state preparation. Hence, variational quantum compiling, due to its robustness, could be practically useful for noisy intermediate-scale quantum devices. Finally, we speculate that this noise resilience may be a general phenomenon that applies to other VHQCAs such as the variational quantum eigensolver.
Coastal margins and backshores represent a major sink for marine debris: insights from a continental-scale analysis
Authors: Olivelli Arianna , Hardesty Britta Denise , Wilcox Chris 
Published: February 2020

Abstract
Marine debris represents a major threat for the environment. Plastic production is increasing exponentially and causing an unprecedented growth of plastic pollution entering the marine environment. Hence, a thorough assessment of debris accumulation areas is required to address the longstanding question about where is all the missing plastic. Most research on marine debris sinks to date has focused on oceanic gyres, the water column, seabeds and wildlife. Relatively little has focused on the potential of coastal areas as debris sinks. To address this knowledge gap, the spatial distribution of debris from the waterline to the backshore was modelled from a continental-scale dataset of coastal debris distribution from 635 surveys across Australia. Results showed that the distribution of debris is significantly correlated with oceanic and atmospheric processes (i.e. onshore Stokes drift and wind), and coastal usage for recreational activities (i.e. regional population and distance to the nearest road). Debris density and size increased from the waterline to the backshore, indicating that the backshore area represents an important debris sink, especially for larger sized items.
Comparison of zooplankton community structure in sea grass ecosystems of Panggang and Semak Daun Islands, Kepulauan Seribu, Indonesia
Authors: Baihaqi F , Krisanti M , Simanjuntak C P H 
Published: February 2020

Abstract
Research on zooplankton assemblage is indispensable for understanding food web dynamics in marine ecosystems. In this study, we elucidated the composition, spatio-temporal distributions and community structure of zooplankton on the sea grass ecosystem of Panggang and Semak Daun Islands, Kepulauan Seribu National Park. Sampling was conducted monthly at fixed stations by vertical tows of 53 μm plankton net from February 2018 to March 2019. During the study period, a total of 52 genera belonging to 38 families of zooplankton were collected. Copepods and protozoans dominated in the zooplankton communities in both sea grass areas. No significant difference was observed in abundance of zooplankton between two sea grass areas of both islands (p > 0.05), however there were a relatively few significant differences of between day and night time catches of zooplankton (p < 0.05). Day time zooplankton was less abundant than night time. Canonical correspondence analysis underlines that zooplankton assemblages were significantly affected by environmental parameters such as salinity, dissolved oxygen, turbidity, and the percentage of sea grass cover. Moreover, the abundance and zooplankton assemblages were well matched with chlorophyll-a concentrations. Since early stage of fishes feeds directly on the zooplankton assemblage, our findings support that sea grass ecosystem plays an important role as a nursery ground for marine fishes.
Marine mini- and micro-shells from some coastal areas, Ao Plao, Ao Yai and Laem Tein Beach, Koh Kut, Trat province, Eastern Thailand
Authors: Bu-on S , Dumgrongrojwattana P 
Published: February 2020

Abstract
Marine minishells and microcells diversity from coastal areas, Ao Plao, Ao Yai and Laem Tein beach, Koh Kut, Trat province, Eastern Thailand have been investigated.From the 3rd to 9th of June, 2019. Specimens were randomly collected from sand sediment and debris in the sandy beach and rocky shore by handpicking. A total of 39 families and 81 species were recorded. At least 35 taxa are enlisted as a new record of the Gulf of Thailand.
Coastal vulnerability index aftermath tsunami in Palu Bay, Indonesia
Authors: Imran Z , Sugiarto S W , Muhammad A N 
Published: February 2020

Abstract
A significant impact of the disaster has influenced a rapid growth of economics for the Palu City 2030 framework. Discovering coastal vulnerability index value is needed to measure tsunami affecting the vulnerability risk and evaluate development plan in 2010-2030. This paper used spatial analysis to estimate coastal vulnerability index (CVI) before and aftermath of the earthquake and tsunami. An assessment of CVI was carried out using seven physical parameters and integrated with the Analytical Hierarchy Process (AHP) to build into five categorized. The result has shown that there was an increased vulnerability risk from moderate to very high rank, where the total amount of area under pressure was 12.8 km2 (56.53%) and rose to 14,367 km2 (63.72%) after the tsunami hit. A coastal area of Ulujati-Mantikulore could be categorized into the very low risk-moderate class; meanwhile, along the region of West Palu, East Palu, North Palu, and Tawaili were indicated into the high-very high-risk class of vulnerability. This paper finding shows that it is needed a decision of policymaker on making a mid/long-term plan, and it should prioritize a precision disaster-based calculation to minimize the loss and damage by the disaster in the future.
Secondary productivity of small Crustacea, Neosesarma sp. in Bintan Island waters, Riau Islands
Authors: Krisanti M , Sofirma A , Hakim A A , Farajallah A , Wardiatno Y , Mashar A 
Published: February 2020

AbstractNeosesarmasp. is a species of Decapods from a family of Sesarmidae.Neosesarmasp. that has an important role in a food chain. The research aimed to estimate secondary productivity ofNeosesarmasp. based on ratio of production and biomass. The research was conducted in 3 stations in Bintan Bay, Bintan Island, Riau Islands. Preliminary research was conducted in August, and the main research was conducted in September, October, and November 2018.Neosesarmasp. was obtained by using modification of artificial substrate. Length and weight were measured and were analyzed to obtain length frequency distribution, length-weight relationship, and estimation of secondary productivity. The length frequency distribution ofNeosesarmasp. ranged from 1.2 to 5.2 mm; both males and female had growth pattern of negative allometric; and the highest secondary productivity (1.5392 gm-2y-1) was in Station 2 located near mangrove ecosystem as original habitat. The lowest secondary productivity (0.0730 gm-2y-1) was in Station 3 (offshore ecosystem). The conclusion of this study isNeosesarmasp. that found in mangrove ecosystem has the highest secondary productivity of another coastal ecosystem in Bintan Island waters.
Diversity of coral reef fish in the coastal water of Spelman Straits, Southeast Sulawesi
Authors: Muis  , Kurnia R , Sulistiono  , Taryono  
Published: February 2020

Abstract
Spelman Strait is one of the potential reef fisheries. This study aims to examine the potential of reef fisheries in the Spelman Strait. The data used in this study are primary data to determine the abundance of reef fish and the use of PaST (Paleontological Statistics) tools to assess diversity, Evenness, wealth, and dominance indices. The results showed that live coral cover from all observation stations was 37.71%. The abundance of reef fish has been under pressure, the diversity index still has good but some families experience threats, the Evenness index value also still shows an even distribution but there are several families threatened, the wealth index still describes good species wealth, but the distribution is uneven, while the dominance index value illustrates that the condition of the coral reef ecosystem is under pressure. This condition is caused by destructive fishing so that the existence of some economically important targeted fish is threatened.
Study of giant clam resources for potential marine tourism in Morella Waters, Central Maluku
Authors: Rabiyanti I , Yulianda F , Imran Z 
Published: February 2020

Abstract
The giant clam is marine mollusk that lives in the coral reef ecosystem and is protected by CITES Appendix II has the high potential object as marine tourism. This study aimed to analyze the potency of clams, which are part of the coral reef ecosystem for the use of diving and snorkeling ecotourism with clams, as the main object in Morella. The parameters used for the analysis of the clam population are 1) density of clams; 2) diversity index and Tourism Suitability Index. There were five species of clams in Morella, such as Tridacna maxima, T. squamosa, T. gigas, T. crocea, and Hippopus hippopus. The widest distribution was shown by T. maxima. The highest population of clam in Lettang Beach was T. squamosa. The highest percentage of coral reef coverage was found at Lubang Buaya Beach at 81.10%, and the lowest was at Hallasy Beach at 55.53%. The highest diversity of reef fish species was found in Lettang Beach, with 197 species. All areas were suitable to be used as tourist attractions for snorkeling activities of clams and reefs. Whereas, Hallasy Beach, Lubang Buaya Beach, and Lettang Beach were suitable to be used for clam and coral attractive object of diving activities.
Seagrass existence after Sunda Strait tsunami 2018: Evidence in Tanjung Lesung region
Authors: Rahmawati A , Khalifa M A , Indaryanto F R , Adrianto L , Agus S B , Kurniawan F 
Published: February 2020

Abstract
The volcanic tsunami occurred at the Sunda strait at the end of 2018. Tanjung Lesung is one of the affected areas, and the seagrass ecosystem allegedly affected too. This research aims to determine seagrass existence in Tanjung Lesung after the tsunami 2018. This research was conducted from June until July 2019 with the same area as the previous study (before tsunami). Observation method using 20 × 0.5 m belt transect sized 50 × 50 cm quadrat. The transect was made perpendicular to the beach line. Seagrass species that were found outside transect also noted. This research found six seagrass species in Tanjung Lesung after tsunami 2018; there were Enhalus acoroides, Cymodocea rotundata, C. serrulata, Syringodium isoetifolium, Halophila ovalis, and Thalassia hemprichii. The most significant impact of tsunami 2018 for seagrass existence sighted in the west part of the cape. Seagrass in the previous observation point has already disappeared and replaced with rock, dead coral, and macro-algae.
Macroplastic distribution, abundance, and composition which flows to Cimandiri estuary, West Java
Authors: Taryono  , Pe E O L , Wardiatno Y , Mashar A 
Published: February 2020

Abstract
Mapping of macro-plastic distribution in the water bodies is important due to the potential of its chemical particle decomposition. Macro-plastic abundance is constituted by population activities which is not accompanied by adequate waste management systems. This study aims to assess the distribution, abundance, and composition of macro-plastic in the water stream of the Cimandiri River from the upper stream to the estuary area. This research was conducted from August to December 2018 using the garbage trap method, with monthly sampling. The results show that the average abundance of macro-plastic is 3.62 x 10-4 items/m3/second with the highest number is in Parung Kuda Station, and the average density is 3.17 x 10-3 kg/m3/second with the highest number is in the coastal area of Palabuhanratu Station. The research shows that plastic packaging is the most portions (42%) of all types of macro-plastic collected which is constructed of low-density polyethylene polymer.
Extraction and microencapsulation of tuna virgin fish oil with mangrove fruit extract fortified into extrusion cereals
Authors: Trilaksani W , Riyanto B , Syifa A L 
Published: February 2020

Abstract
Long-chain omega-3 fatty acids (LCn-3FA) originally from fish have been recognized plays an important role in improving health status. Fortification these LCn-3FAs into foodstuffs will enhance their nutritional and functional value, however, their vulnerability, particularly to oxidation, requires extra protection. The goals of the research were to produce tuna eyes extra virgin fish oil (EVFO) microcapsules rich in DHA protected by mangrove fruit extract as a natural antioxidant and to obtain an extruded cereal with EVFO microcapsules. EVFO was extracted using cool centrifugation, microencapsulated by maltodextrin and arabic gum, and the cereal was formulated as extrusion flake products. The proportion of EVFO extracted from tuna eyes was 10.3596±0.73%. Mangrove fruit extract had a strong antioxidant activity with IC50 of 53.28 ppm. The best microcapsules were gained from arabic gum-maltodextrin coating material and the addition of 4000 ppm of mangrove fruit extract, which had an efficiency value of 93.71%, and round shape with size 6.26 μAm. Cereal with 35 g serving sizes and the addition of 3.6% EVFO microcapsules contributed approximately 134 kcal, 100 mg DHA, and 125 mg omega-3 increasing the great nutritional value.