bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on the Effect of Reduction Distribution in Universal Stands on the Process of Metal Transition from Sides to the Center Line of Transfer Bar
Authors: Polyakov A V , Mazur I P 
Published: January 2020

Abstract
The edge defects formed on the continuously cast slab before entering the hot rolling mill in the roughing group of the broadband mill are moved from the side faces and edges of the slab to the upper and lower surface of the slab. This process is facilitated by alternating compression in vertical and horizontal rolls. This article describes the transition of a metal from the edges and side faces of the slab at the top and bottom surfaces of the slab sheet during rolling in universal stands of the roughing stands of the hot rolling mill. The amount of movement of the defects on the surface of the slab directly affects the amount of lateral trim is necessary for assured removal of marginal defects in subsequent processing. The presented mathematical model based on the finite element method includes compression of continuously cast slab in three separate stands consisting of vertical and horizontal rolls. The influence of a number of technological parameters and modes of adjustment of the vertical rolls on the value of the metal displacement to the center line of the transfer bar is studied.
Algorithm and Design Methodology for Energy-Efficient Sheet Products Production Technology
Authors: Shalaevskiy D L , Kozhevnikov A V 
Published: January 2020

Abstract
The work presents a calculation method for technology parameters of the continuous cold rolling process of wide steel strips, based on the determination of such reductions by stands and interstand tension, at which the technological process will be ensured with maximum productivity and minimum energy consumption. A method for calculating the rolling parameters is proposed, which will provide the minimum level of energy consumption by the main drives’ motors of the rolling stands at the maximum productivity of the continuous mill by eliminating vibrations in the working stands. The created methodology can be used as a base for the software of continuous mills.
Formation of the Structure and Decarburized Layer During Hot Screw Rolling of Vessels
Authors: Shatalov R L , Medvedev V A 
Published: January 2020

Abstract
We studied the influence of temperature and soaking time on rod billets made of steel 50. The development of the decarburized layer after induction heating and soaking in the resistance furnace was taken into account. When analyzing cooled down rod billets subjected to heat treatment, a continuous and stable development of a ferritic layer on the entire surface of rod billets was detected. Rod billets heated in a similar way as those on which the size of the outer decarburized layer had been defined were hot rolled. Experimental rolling was performed in a 3-high stand of the rolling-press line of JSC Scientific Production Association (SPA) “Pribor”. After cooling it was found that the sizes of a ferrite ring on the outer surface of steel vessels had changed. The analysis of the obtained data allowed us to find a relationship between the change in the structure of a ferrite ring formation and a draw ratio λ. A regression equation was obtained for determining the influence of drawing during screw rolling on the size of a decarburized layer.
Aeroacoustics of Jet Streams Used in Metallurgy
Authors: Shlik O 
Published: January 2020

Abstract
The supersonic jets of gas which is expiring into the melt from nozzle of BOF lance have a powerful acoustic radiation. The sound intensity of the jets is up to 200 dB and it is the most powerful natural source of sound. The jets invasion into heterogeneous unstable and gas saturated liquid melt-solution is the cause of the cavitation phenomena into the liquid. This explains the spontaneity of the gas formation and the speed of the decarburization process throughout the entire volume of the liquid metal volume. Using sound intensity changes, in the 60-th years of the last century, was developed the acoustic monitoring and control system of slag process into the BOF furnace.
Nanomodification of Refractories with Finely-Dispersed Additives with the Use of a Vortex Electromagnetic Homogenizer
Authors: Suvorov D S , Khaidarov B B , Lysov D V , Kuznetsov D V , Zhukova P A , Kazakov V I , Gorchakov V V 
Published: January 2020

Abstract
The article presents the laboratory and industrial research and the analysis of the impact of modification of refractory concretes and products with finely-dispersed nanomaterials. The dependence of the structural and physical-mechanical characteristics of mullite-corundum refractories of different types (for ladle furnace lances and for supporting blocks of rolling mill carriages) on nanomodification by electromagnetic homogenization is shown. The possibility of using a vortex electromagnetic homogenizer to significantly improve the performance of refractories is shown. In addition, the efficiency of using nanodispersed silicon dioxide is established and its optimal concentration is determined.
Effective Materials from Recycled Aluminum Waste for Steel Ladle Treatment
Authors: Tribushevskiy L V , Rumyantseva G A , Nemenenok B M 
Published: January 2020

Abstract
The paper presents the results of research on the use of recycled aluminum waste (RAW) for steel ladle treatment. It has been established that simultaneously with the deoxidation of refining slags before desulfurization of steel, their liquid mobility increases, which eliminates the need for using fluorspar for these purposes. A thermodynamic analysis of possible reactions of formation of aluminates and calcium aluminosilicates in the refining slag has been carried out. The composition of briquettes based on RAW for liquefaction of refining slags is proposed.
2020 Technology and Operation of a Hot Rolling Mill
Authors: Vanderschueren D 
Published: January 2020

Abstract
The state-of-the-art of both technology and operational practice of a hot rolling mill are discussed. The focus is first on the control of entry temperature in the finish mill. Transfer bar cooling and induction heating are presented. Next, the safe keeping in the finishing mill of surface quality, crown and flatness are discussed. Important tools to achieve these properties are lubrication, friction measurement, roll cooling, inter stand and skin cooling, bending, shifting and prediction of roll forces. The third and final topic is the run- out table cooling. Ultra-fast cooling is compared with laminar cooling. The cooling strategies and their importance to realise the required micro-structure and properties are discussed for hot rolled Dual Phase steel, pipe line grades and rebar.
Experimental Investigations of Physical Properties of Iron-Copper Alloy
Authors: Vdovin K N , Dubskiy G A , Egorova L G , Nefedyev A A 
Published: January 2020

Abstract
The paper describes the results of experiments aimed at obtaining iron-copper alloys with different iron content using electroslag remelting method. The obtained alloys of iron and copper were carefully examined to study their mechanical and physical properties. The article shows the results of the research work investigating the influence of iron on crystallization characteristics of the copper alloy. It was found, that iron-copper alloys can compete successfully with expensive copper-silver alloys, which are used to manufacture mold walls. The article offers the results of the experiments investigating hardness, wear resistance, thermal conductivity and temperature conductivity of the obtained iron-copper alloys; their casting characteristics were also studied.
On Capabilities of People with Health Limitations in Terms of Industrial Business
Authors: Denisova O A , Lekhanova O L 
Published: January 2020

Abstract
The Resource Training and Methodical Center (RTMC) for training people with disabilities, based at the Cherepovets State University, presents its experience and research results in terms of identifying the capabilities of people with disabilities as a human resource for industrial business. The authors demonstrate that over the past few years the number of people with disabilities focused on inclusive employment in industry has been increasing. The specifics of careers chosen by people with disabilities and their special needs prove that cooperation between industrial business and a network of Resource Training and Methodical Center for training people with disabilities is a must.
Printability study of metal ion crosslinked PEG-catechol based inks
Authors: Włodarczyk-Biegun Małgorzata K , Paez Julieta I , Villiou Maria , Feng Jun , del Campo Aranzazu 
Published: January 2020

Abstract
In this paper we explore the printability of reversible networks formed by catechol functionalized PEG solutions and metal cations (Al3+, Fe3+ or V3+). The printability and shape fidelity were dependent on the ink composition (metal ion type, pH, PEG molecular weight) and printing parameters (extrusion pressure and printing speed). The relaxation time, recovery rate and viscosity of the inks were analyzed in rheology studies and correlated with thermodynamic and ligand exchange kinetic constants of the dynamic bonds and the printing performance (i.e. shape fidelity of the printed structures). The relevance of the relaxation time and ligand exchange kinetics for printability was demonstrated. Cells seeded on the materials crosslinked with Al3+, Fe3+ ions were viable and revealed well-spread morphologies during 7 day culture, indicating the potential of the formulations to be used as inks for cell encapsulation. The proposed dynamic ink design offers significant flexibility for 3D bioprinting, and enables straightforward adjustment of the printable formulation to meet application-specific needs.
Magneto-optical Kerr effect in spin split two-dimensional massive Dirac materials
Authors: Catarina G , Peres N M R , Fernández-Rossier J 
Published: January 2020

Abstract
Two-dimensional (2D) massive Dirac electrons possess a finite Berry curvature, with Chern number

1/2, that entails both a quantized dc Hall response and a subgap full-quarter Kerr rotation. The observation of these effects in 2D massive Dirac materials such as gapped graphene, hexagonal boron nitride or transition metal dichalcogenides (TMDs) is obscured by the fact that Dirac cones come in pairs with opposite sign Berry curvatures, leading to a vanishing Chern number. Here, we show that the presence of spin–orbit interactions, combined with an exchange spin splitting induced either by diluted magnetic impurities or by proximity to a ferromagnetic insulator, gives origin to a net magneto-optical Kerr effect in such systems. We focus on the case of TMD monolayers and study the dependence of Kerr rotation on frequency and exchange spin splitting. The role of the substrate is included in the theory and found to critically affect the results. Our calculations indicate that state-of-the-art magneto-optical Kerr spectroscopy can detect a single magnetic impurity in diluted magnetic TMDs.
Theoretical investigation of thioguanine isomers anticancer drug adsorption treatment on B12N12 nanocage
Authors: Noormohammadbeigi Motahareh , Kamalinahad Saeedeh , Izadi Farhad , Adimi Maryam , Ghasemkhani Alireza 
Published: January 2020

Abstract
Density functional theory (DFT) method used to investigate the interaction of thioguanine isomers with B12N12 nanocage in several media to earn electronics properties. To achieve this purpose, adsorption of thioguanine isomers on the exterior surface of B12N12 investigated in the gas phase and water media. Optical structures, electronic properties, and natural bond orbitals (NBO) analysis display that the adsorption of thioguanine on B12N12 nanocage is a strong chemisorption in the gas phase as well as water media. Besides, the electronic conductance of nanocage is significantly altered once the thioguanine isomers molecules are adsorbed. Thus, the energy gap between HOMO and LUMO orbitals is reduced which could be applied as a chemical signal to confirm chemical adsorption. Moreover, the relative dipole moments calculated for obtained configurations suggest that these structures could be solubilized or dispersed in polar mediums like water. Based on results, B12N12 nanocage could be a potential carrier for delivering thioguanine isomers in nanomedicine applications.
Nanostructured polycrystalline Ni3S2 as electrode material for lithium ion batteries
Authors: Khan I A , Medwal R , Fareed S , Farid A , Vas J V , Reddy M V , Rawat R S 
Published: January 2020

Abstract
We report the facile synthesis of nanostructured polycrystalline nickel sulphide (NP-Ni3S2) on Ni foil at 750 and 800 °C by employing powder vapor transport technique. X-ray diffraction patterns (XRD) confirms the formation of polycrystalline Ni3S2 phase with rhombohedral structure. Raman spectroscopy and x-ray photo-electron spectroscopy (XPS) further confirms the formation of Ni3S2 phase. Scanning electron microscopy (SEM) reveals the formation of flower shaped nanostructures of NP-Ni3S2 material. As an electrode material of Li+ batteries, the initial discharge capacities for NP-Ni3S2 materials deposited at 750 and 800 °C are found to be ∼2649 mAh g−1 and ∼1347 mAh g−1, respectively with initial capacity loss of ∼1067 mAh g−1 and ∼363 mAh g−1 after first cycle and capacities of ∼931 mAh g−1 and ∼818 mAh g−1 after 30 cycles for a current density of 60 mA g−1. An excellent capacity retention for NP-Ni3S2 material synthesized at 800 °C is due to its larger surface area and shorter diffusion length for mass and charge transport brought about by the flower-like porous nanostructures showing that the NP-Ni3S2 material synthesized at higher temperatures is more suitable as electrode material for Li+ batteries.
Development of BSA conjugated on modified surface of quercetin- loaded lipid nanocarriers for breast cancer treatment
Authors: Kumar Rahul , Choudhary Dhiraj Kumar , Debnath M 
Published: January 2020

Abstract
Multiple drug resistance is a key limitation for the clinical administration of chemotherapeutic drugs, apart from this their major limitations with free drugs are poor solubility, physiochemical and pharmaceutical behavior. These limitations with free drugs can be overcome by nanoformulations using natural biopolymer. In this study, successful utilization of P-glycoprotein receptor for the delivery of anticancer drug quercetin (Q), encapsulated inside the lipid nanocarriers (LNs) was introduced for the treatment of breast cancer. Bovine serum albumin (BSA) was conjugated on the Q-loaded LNs( BSA-Q-LNs) for targeting to receptor. Q-loaded LNs were prepared using a single emulsion solvent evaporation method, followed by surface modification of Q-loaded LNs using charge interaction. Finally, surface modified Q-loaded LNs were conjugated with BSA using thiol reaction. The formulated nano construct was a spherical structure with a shell size of 530 nm. Encapsulation of Q inside the matrix of LNs is confirmed from shift in FT-IR, XRD peak. The release kinetic of Q- loaded LNs formulation was best fitted in a first-order kinetic model suggesting early burst of Q followed by slow release. The entrapment efficiency and drug loading efficiency were found to be 76 ± 0.3% and 15.72 ± 0.7% respectively. The Q-loaded LNs and BSA-Q-LNs displayed the improved cytotoxicity in drug resistance human breast cancer cell line (MCF-7) as compared to free Q.
The effect of rare earth elements on the work softening behavior of as-cast Mg-4Al-2Sn
Authors: Jalali M S , Zarei-Hanzaki A , Jamili A M , Abedi H R , Mosayebi M , Vakili S M 
Published: January 2020

Abstract
This work explores the addition of 1% Rear Earth (RE) elements on the Mg–4Al–2Sn magnesium alloy, with an emphasis laid on the microstructural evolution during solidification and subsequent hot deformation behavior. The morphology of the α-Mg dendrites changes from the butterfly-like (growth at the non-basal planes) to the snow-flake like (growth at the basal planes) due to the addition of RE elements. Dendrite morphology transition (orientation transition) lead to the formation of the various macro-texture at the solidification interval. Subsequently, an appropriate correlation was established between the dendrite orientation selection, solidification texture and deformation behavior of the as-cast microstructure. The workability increases due to the addition of RE elements, which is related to the initial solidification texture and the morphology of the α-Mg dendrites. The results indicated that the dendrites which have snow-flake like morphology in the RE bearing alloys was more favorable for breaking of as-cast microstructure and occurrence of dynamic recrystallization.
Structure and optical properties of polycrystalline ZnSe thin films: validity of Swanepol’s approach for calculating the optical parameters
Authors: Hasaneen M F , Alrowaili Z A , Mohamed W S 
Published: January 2020

Abstract
Ultrasonically cleaned glass slides are used as substrates for receiving the different thickness of Zinc selenide (ZnSe) films. The deposition processes of our investigated films were done at room temperature using physical thermal evaporation mechanism under vacuum ≈2 × 105 mbar. We investigated the optical and structural parameters of ZnSe thin films in correlation with film thickness (200–650 nm). Various techniques such as UV–vis-NIR spectrophotometer, x-ray diffraction lines and field emission scanning electron microscope were used to investigate aforementioned parameters. Structural analysis indicate that the films exhibited cubic preferred orientation along the plane (111) and the crystallinity and crystallite size of films increases linearly with film thickness. The optical band gap ranges from 2.69 to 2.81 eV and it is founded that it increases with film thickness. According to the applied Swanepoel’s approach, it is possible to estimate the optical parameters and average thickness of the ZnSe thin films of different thicknesses with higher accuracy.
An investigation on the synergistic effect of Cu2O-Ag nanoparticle on its bactericidal and anticancerous properties
Authors: Karle Ashish , E Deepa , Kapur Ibani , Therese Helen Annal 
Published: January 2020

Abstract
Copper and silver are known to have good antibacterial and anti- fungal properties at nanoscale. Cu2O-Ag synthesis was attempted using hydrazine hydrate reduction method. The formation of Cu2O-Ag nanoparticles was confirmed using powder x-ray diffraction technique. Further the morphology and elemental compositions were analyzed by FESEM, HRTEM and XRF techniques. The antibacterial activity of the formed nanoparticles exhibited an excellent zone of inhibition compared to the existing antibiotics. The microbial broth curve obtained against Pseudomonas aeruginosa further confirmed the remarkable inhibiting property of the nanoparticle in a short span of 6 h post treatment (HPT). The synthesized nanoparticle showed very good activity against HCT-15 colon cancer cells by inhibiting their viability up to 27% when treated at higher concentration. Thus the synthesized nanoparticles seem to be a good candidate for various biological applications.
Haemoglobin causes neuronal damage in vivo which is preventable by haptoglobin
Authors: Garland Patrick , Morton Matthew J , Haskins William , Zolnourian Ardalan , Durnford Andrew , Gaastra Ben , Toombs Jamie , Heslegrave Amanda J , More John , Okemefuna Azubuike I , Teeling Jessica L , Graversen Jonas H , Zetterberg Henrik , Moestrup Soren K , Bulters Diederik O , Galea Ian 
Published: January 2020

AbstractAfter subarachnoid haemorrhage, prolonged exposure to toxic extracellular haemoglobin occurs in the brain. Here, we investigate the role of haemoglobin neurotoxicity in vivo and its prevention. In humans after subarachnoid haemorrhage, haemoglobin in cerebrospinal fluid was associated with neurofilament light chain, a marker of neuronal damage. Most haemoglobin was not complexed with haptoglobin, an endogenous haemoglobin scavenger present at very low concentration in the brain. Exogenously added haptoglobin bound most uncomplexed haemoglobin, in the first 2 weeks after human subarachnoid haemorrhage, indicating a wide therapeutic window. In mice, the behavioural, vascular, cellular and molecular changes seen after human subarachnoid haemorrhage were recapitulated by modelling a single aspect of subarachnoid haemorrhage: prolonged intrathecal exposure to haemoglobin. Haemoglobin-induced behavioural deficits and astrocytic, microglial and synaptic changes were attenuated by haptoglobin. Haptoglobin treatment did not attenuate large-vessel vasospasm, yet improved clinical outcome by restricting diffusion of haemoglobin into the parenchyma and reducing small-vessel vasospasm. In summary, haemoglobin toxicity is of clinical importance and preventable by haptoglobin, independent of large-vessel vasospasm.
Easy One-Step Amplification and Labeling Procedure for Copy Number Variation Detection
Authors: Blesa Sebastián , Olivares María D , Alic Andy S , Serrano Alicia , Lendinez Verónica , González-Albert Verónica , Olivares Laura , Martínez-Hervás Sergio , Juanes José M , Marín Pablo , Real Jose T , Navarro Blanca , García-García Ana B , Chaves Felipe J , Ivorra Carmen 
Published: January 2020

Abstract

Background
The specific characteristics of copy number variations (CNVs) require specific methods of detection and characterization. We developed the Easy One-Step Amplification and Labeling procedure for CNV detection (EOSAL-CNV), a new method based on proportional amplification and labeling of amplicons in 1 PCR.

Methods
We used tailed primers for specific amplification and a pair of labeling probes (only 1 labeled) for amplification and labeling of all amplicons in just 1 reaction. Products were loaded directly onto a capillary DNA sequencer for fragment sizing and quantification. Data obtained could be analyzed by Microsoft Excel spreadsheet or EOSAL-CNV analysis software. We developed the protocol using the LDLR (low density lipoprotein receptor) gene including 23 samples with 8 different CNVs. After optimizing the protocol, it was used for genes in the following multiplexes: BRCA1 (BRCA1 DNA repair associated), BRCA2 (BRCA2 DNA repair associated), CHEK2 (checkpoint kinase 2), MLH1 (mutL homolog 1) plus MSH6 (mutS homolog 6), MSH2 (mutS homolog 2) plus EPCAM (epithelial cell adhesion molecule) and chromosome 17 (especially the TP53 [tumor protein 53] gene). We compared our procedure with multiplex ligation-dependent probe amplification (MLPA).

Results
The simple procedure for CNV detection required 150 min, with &lt;10 min of handwork. After analyzing &gt;240 samples, EOSAL-CNV excluded the presence of CNVs in all controls, and in all cases, results were identical using MLPA and EOSAL-CNV. Analysis of the 17p region in tumor samples showed 100% similarity between fluorescent in situ hybridization and EOSAL-CNV.

Conclusions
EOSAL-CNV allowed reliable, fast, easy detection and characterization of CNVs. It provides an alternative to targeted analysis methods such as MLPA.
Are We Ready for Proactive Therapeutic Drug Monitoring of Anti-TNF to Optimize Care of Patients With Inflammatory Bowel Disease?
Authors: Charabaty Aline 
Published: January 2020

Lay Summary
Some patients with inflammatory bowel disease clear anti-TNF drugs out of their blood faster than others, and if there is not enough drug in the body, then the drug cannot control the bowel inflammation properly. Therapeutic drug monitoring is checking the drug level in the blood of patients to help adjust the treatment and make it more effective.