bluuebunny/crossref_metadata_2025_split huggingface dataset:
Micromorphological variation forage crops of Loliinae subtribe (Poaceae)
Authors: Keshavarzi Maryam , Tabaripour Raheleh 
Published: April 2020

Abstract
Background: Loliinae subtribe (Poaceae) composed of famous temperate grasses with forage and ornamental importance worldwide. Some elements as Lolium, Festuca and Vulpia are widely used as fodder and ornamental in gardens. In present project micromorphological characters of lemmas and paleas using scanning electron microscopy for 56 taxa of 32 species of Loliinae, have been investigated. In present project micromorphological characters of lemmas and paleas using scanning electron microscopy for 56 taxa of 32 species of Loliinae, have been investigated. By evaluating these set of features in abaxial lemma and palea, we aimed to clarify the taxonomic value in this subtribe for the first time. Other purpose of present study was to assess the impact of silica bodies and epicuticular wax in species for livestock palatability.Results: Features studied including long cells length, long cells shape, periclinal wall of long cells, short cells, silica cells, prickles, prostration of crown cells thin layer of crown cells, macroharis and wax shape. Two new types of lemma and palea micromorphological traits were introduced here. Multivariate data analysis was obtained using PAST software.Conclusions: Lolium temulentum is a toxic weed and recorded as dangerous for livestock because of having increased amount of wax and silica bodies at the vegetative parts. Taxa relationships were discussed based on micromorphological characters and the results were in concordance with the previous molecular findings. Although some genera studied, were not grouped properly.
A Comparative Study of the Status of Supportive-Palliative Care Provision in Iran and Selected Countries: Strengths and Weaknesses
Authors: raeissi pouran , salimi mohammad , Hashemi Seyed-Masoud , Reisi nahid , ahmadi seyed ahmad 
Published: April 2020

Abstract

Background: Terminally illnesses such as cancer, AIDS, dementia, and advanced heart disease will require special supportive and palliative care, although a few numbers of these patients are provided with these services.Objective: The present study was conducted aiming to perform a comparative study of supportive-palliative care provision in selected countries.Methods: This research was a descriptive-comparative study that its research population was the frameworks of palliative and supportive care provision in Egypt, Turkey, America, Australia, Canada, the Netherlands, and China. These frameworks were compared across 6 dimensions of service receivers, financing, providers, service provider centers, type of services provided and training. Data collection tool has included checklist and information sources, documents, evidence, articles, books and journals collected through the internet and organizations related to the health information of selected countries and by library search. Data was investigated and analyzed using data collection tool and checklists.Findings: The findings showed that the developed countries having decentralized trusteeship structure had a more favorable status in palliative and supportive care provision. The type of services provided was a combination of mental, psychological, social, spiritual, financial, and physical and communication services. Provider centers included hospital, the elderly, and cancer, and charity centers.Conclusion: Regarding the investigation and recognition of the status of supportive-palliative care provision, it was observed that the provision of these services was a concern of the selected countries, but they did not have a defined model or pattern to provide these services. Therefore, it is suggested that each country takes a step to redesign and define frameworks and structures in the evolution of supportive-palliative cares in accordance with the particular conditions, indigenous culture, religion and other effective cases of that country and pays special attention to the role and position of supportive-palliative cares.
Low-density lipoprotein cholesterol within the normal range and nonalcoholic fatty liver disease in the non-obese Chinese population: a secondary analysis based on a cross-sectional study
Authors: Xu Zhigang (N/A) , Xu Baohong 
Published: April 2020

Abstract
Background

Evidence regarding the relationship between normal low-density lipoprotein cholesterol (LDL-c) levels and non-alcoholic fatty liver disease (NAFLD) was limited. Therefore, this dissertation seeks to investigate the relationship between LDL-c and NAFLD in the non-obese Chinese population after adjusting for other covariates.
Methods

The present study was a cross-sectional study. A total of 183903 non-obese participants were involved in a Wenzhou Medical Center of Wenzhou People’s Hospital from 2010 to 2014. The target independent variable and the dependent variable were LDL-c measured at baseline and NAFLD respectively. Covariates involved in this study included SEX, AGE, BMI, SBP, DBP, FPG, ALB, ALT, AST, BUN, Cr, TG, TC, HDL-c, UA. It was noted that the entire study was completed by Dan-Qin Sun et al., and uploaded the data to the DATADRYAD website. The author only used this data for secondary analysis.
Results

The average age of 183903 selected participants was 41.0 ± 14.1 years old,and about 49.6% of them was male. After adjusting potential confounders (SEX, AGE, BMI, FPG, ALB, GLB, ALT, AST, GGT, BUN, Cr, TG, TC, HDL-c, UA), non-linear relationship was detected between normal LDL-c levels and NAFLD, whose point was 1.51. The effect sizes and the confidence intervals on the left and right sides of inflection point were 0.87 (0.64, 1.18) and 1.79 (1.67, 1.92), respectively.
Conclusion

The relationship between normal LDL-c levels and NAFLD is non-linear. Normal LDL-c levels was positively correlated with NAFLD when LDL-c was more than 1.51.
Association of potato and other starchy vegetable consumption with cardiovascular diseases risk factors in Iranian elderly men
Authors: Basiry Mursal , Daneshzad Elnaz , Mozaffari Hadis , Azadbakht Leila 
Published: April 2020

Abstract
Objectives.

Given the limited research on potato and other starchy vegetable consumption with cardiovascular diseases (CVD), we examined the association of potato and other starchy vegetable intakes in association with cardiovascular risk factors and inflammatory biomarkers among elderly men.
Study Design.
A cross-sectional study.
Methods.

In this study, 357 elderly men were participated. Dietary intake was assessed using food a valid and reliable frequency questionnaires. Two separated groups were considered. 1. Potato, 2. Other Starchy vegetables including corn, squash, green pea, and green lima beans. CVD risk factors including HDL, LDL, FBS, TG, TC, Alkaline phosphatase, Fibrinogen, Insulin, IL-6, TNF-α, SGOT and SGPT were measured.
Results.

Participants in the highest tertile of potato consumption had a 45% lower serum level of fasting blood sugar (OR: 0.55; 95%CI: 0.31, 1.97; P trend: 0.041). However, this significant association disappeared after controlling for confounders. The participants in the highest tertile of potato consumption had higher serum level of triglyceride (OR: 4.52 95%CI: 1.10, 18.56; P trend: 0.030). Moreover, participants in the highest tertiles of other starchy vegetable consumption had an 84% lower serum level of alanine aminotransferase (OR: 0.16 95%CI: 0.03, 0.90; P trend: 0.040).
Conclusion.

Overall, more consumption of potato may be related to developing CVD risk factors. Future research is needed to elucidate the association between potato and other starchy vegetable consumption with cardiovascular diseases risk factors in both genders.
Re-examining the Impact of Financial Development on the Economic Growth of North Cyprus Through the Moderating Role of the Education Sector
Authors: Giritli Nuru , Kalmaz Demet Beton 
Published: April 2020

Abstract
This study examines the impact of financial development on economic growth with the multiplier effect of the higher education by employing yearly data covering the years between 1990 and 2018 measured in TL. The results reached could shape the policies in achieving sustainable economic growth. Co-integration between the series are tested with ARDL based bounds test; since Zivot-Andrews structural unit root test results showed that variables are integrated at different orders. Furthermore, FMOLS and DOLS are applied to check for robustness. Moreover, Toda-Yamamoto Causality test is employed to test for the causal relationship between the series. Results show that there is a bidirectional causal relationship between financial depth and economic growth; and unidirectional causal relationships from money supply to financial depth, from economic growth and financial depth to education sector. Diagnostic and stability tests results confirm the reliability and stability of the parameters of the model employed.
Determinants of Rural Households’ Vulnerability to Food Insecurity in Gamo Gofa Zone, Southern Ethiopia
Authors: Eshetu Fassil 
Published: April 2020

Abstract
The aim of this study was to measure the level and determinants of rural households’ vulnerability to food insecurity using a sample of 574 households and feasible generalized least square method. Results showed that the mean level of food insecurity at high land, low land and middle land areas are 73.12, 77.11 and 52.24 percent respectively. But mean level of vulnerability to food insecurity at high land, low land and middle land areas are 76.87, 84.32 and 55.62 percent respectively. The overall level of food insecurity and vulnerability to food insecurity in the study area are 68.31 and 73.34 perecent respectively. Thus, vulnerability to food insecurity is more wide spread in the study areas particularly in moisture stress low land area. Logistic regression showed that age of household, family size, off farm income, safety net programs, distance from health, death of household members and death of animals significantly increase rural households’ vulnerability to food insecurity. But, farm income, irrigation use and credit uses significantly decrease rural households’ vulnerability to food insecurity. Hence, government may help rural households to gather more resources and reduce vulnerability to food insecurity via better access to credit, infrastructure, irrigation uses and population control.
The Median Survival Recovery Time and Associated Factors Among Admitted Neonate in Intensive Care Units of Dire Dawa Public Hospitals, East Ethiopia, 2019.
Authors: Derese Tariku , Belay Yalelet , Tariku Zerihun 
Published: April 2020

Abstract
Background

Neonate is any infants from the birth to 28 days. Most of the neonatal deaths occur in developing countries particularly in sub-Saharan African and south central Asian countries. The ability to predict Length of stay would be valuable to parents and families, clinicians and service providers. Timely Management and treatment of birth complication are important factors in reducing new born mortality.
Objective

The median Survival Recovery time and associated factors among admitted neonate in intensive care units of Dire Dawa Governmental Hospitals, East Ethiopia, 2019.
Methods

Facility based retrospective cohort study design was employed to assess recovery time and associated factors of neonate among a total of 499 selected 0–28 days of neonates from two public Hospitals and validated Checklist were used to assess data. Data were entered in to Epi-data version 3.1 and exported to SPSS window version 21.0. Descriptive data were presented by table and graph. To determine the associated factors, Cox regression model was computed with 95% CI and P-value < 0.05 level of significance. Ethical clearance was taken from Dire Dawa University research and technology interchange office and given for all concerned body.
Result

The overall median survival recovery time of neonates admitted in neonatal intensive care units of Dire Dawa public hospital was 7 Days with 95% CI (6.525–7.475). Among the neonates that admitted in neonatal intensive care units, neonates those who have weight < 2500 g had 1.648 times higher hazard risks to recovery compared to that neonates who have weight greater than or equal to 4000 g with [AHR 1.648 95% CI (1.246–2.179)]. Those neonates who were none intubated had 6.725 higher hazard risks compared to that of intubates neonates [AHR 6.725 95% CI (1.616–27.978)], and those neonates who were not supply oxygen continuously had 1.336 times low probability to for recovery [AHR 1.336 95% CI (1.030–1.733)]. But, the neonates admitted between 1–6 days after birth had 0.521 times higher probability for recovery compared to the neonate with those neonate admitted between 7–28 days of after birth [AHR 0.521 95% CI (0.355–0.763)].
Conclusion

Overall median survival recovery time was 7 Days and Birth weight of neonates, Oxygen supply, and Intubation and admission time of neonate between 1–6 days of after birth were factors that significantly associated with recovery time of neonates. Compared to the other study the recovery time of neonates in this study were short and better.
Correlation of MET and PD-L1 expression in malignant melanoma
Authors: Song Kyu Young , Desar Sabina , Pengo Thomas , Shanley Ryan , Giubellino Alessio 
Published: April 2020

Abstract
Background: The proto-oncogene MET, the hepatocyte growth factor (HGF) receptor, is a transmembrane receptor tyrosine kinase (RTK) with a prominent role in tumor metastasis and resistance to anti-cancer therapies. Melanoma demonstrates relatively frequent MET aberrations, including MET gene amplification. Concurrently, PD-L1, with its ability to evade anti-tumor immune responses, has emerged as a prominent therapeutic target in melanoma and other malignancies and its expression is used as a predictive biomarker of response to immunotherapy. Methods: We performed immunohistochemistry analysis of MET and PD-L1 in 18 human melanoma cell lines derived from both primary and metastatic lesions; we then performed the same analysis in a human melanoma tissue microarray (TMA) containing 100 melanocytic lesions, including 42 cutaneous malignant melanomas, 20 mucosal melanoma, 21 metastatic melanomas and 17 benign melanocytic nevi as controls. After color deconvolution, TMA cores were identified and segmented to isolate staining and calculate the percentage of positive cells in each core. Results: Overall, MET expression was higher in metastatic lesions and it was higher in tumors with increased PD-L1 expression. Moreover, a positive correlation between MET and PD-L1 expression was found in metastatic melanoma. Conclusions: These data suggest that testing for expression of these markers should be conducted in patients with melanoma with metastatic disease and selective therapies targeting these proteins should be considered for advanced disease.
Early histologic findings of pulmonary SARS-CoV-2 infection detected in a surgical specimen.
Authors: Angelina Pernazza , Mancini Massimiliano , Rullo Emma , Bassi Massimiliano , Giacomo Tiziano De , Rocca Carlo Della , d'Amati Giulia 
Published: April 2020

Abstract
Despite the current pandemic season, reports on pathologic features of Coronavirus disease 19 (COVID-19) are exceedingly rare at the present time. Here we describe the pathologic features of early lung involvement by COVID-19 in a surgical sample resected for carcinoma from a patient who developed SARS-CoV-2 infection soon after surgery. The main histologic findings observed were pneumocyte damage, alveolar hemorrhages with clustering of macrophages, prominent and diffuse neutrophilic margination within septal vessels and interstitial inflammatory infiltrates, mainly represented by CD8+ T lymphocytes. These features are similar to those previously described in SARS-CoV infection. Subtle histologic changes suggestive pulmonary involvement by Covid-19 may be accidentally encountered in routine pathology practice, especially when extensive sampling is performed for histology. These findings should be carefully interpreted in light of the clinical context of the patient and could prompt a pharyngeal swab PCR test to rule out the possibility of SARS-CoV-2 infection in asymptomatic patients.
Effective adsorbents for removal Cd(II) ion in solution from activated carbon of palm oil shell coated with magnetite particles
Authors: . Buhani , . Suharso , Rilyanti Mita , Sari Miranda , . Sumadi 
Published: April 2020

Abstract
Investigation of the ability of activated carbon (AC) adsorption from modification of palm oil shells by coating magnetite (Fe3O4) particles to Cd(II) ions in solution was studied through a series of adsorption experiments with a bacth method. The activated carbon adsorbents (PPAC-P) and the activated carbon-magnetite (PPAC-MnPs) were characterized by Fourier transform spectrometer to identify the functional groups, X-ray diffraction to study the level of material crystallization, scanning electron microscopy-energy-dispersive X-ray analysis to analyze the surface morphology of material and element constituents, as well as Brunauer-Emmett-Teller analyzer to analyze the surface areas of the adsorbents. The concentrations of Cd(II) ions in the solution were determined using atomic absorption spectrophotometer. The adsorption process of Cd(II) ions by PPAC-P and PPAC-MnPs was optimum at pH 6 and 7 with contact time of 90 minutes, respectively. The adsorption kinetics of Cd(II) ions in PPAC-P and PPAC-MnPs have a tendency to follow the pseudo second-order kinetics model and the Freundlich adsorption isotherm model with a value of R2 > 0.99. These suggested that the adsorption process of the Cd(II) ions on PPAC-P and PPAC-PMnPs were described as heterogeneous adsorption. PPAC-PMnPs adsorbents can be used repeatedly with % Cd(II) ions adsorbed almost constant for 4 cycles with adsorption efficiency > 80%.
BbNCPD-Bayesian belief Network Based Contextual Polarity Disambiguation in Sentiment Analysis
Authors: Singh Tajinder , Kumari Madhu 
Published: April 2020

Abstract
Sentiment analysis has enormous contributions and vivid utility in many areas of natural language processing, e-commerce and social network analysis. Although there are several methods designated for this task but major thrust of this domain to develop machine learning based polarity classification of user generated text, review and post. It is even tougher to classify the text containing multi-polarity words. In the meantime, several studies have discussed and focused on contextual information of word in Natural Language Processing. But, due to lack of methodologies, it becomes challenging for contextual polarity disambiguation because no evidence is available which proves that whether the sentiment expressed by the context is correctly identified. Therefore, in this work an effort to compute the quantified amount of polarity of terms/words in a given text, based on its local as well as global contexts. The proposed work contains two major parts, firstly it extracts the local and global features from semantic dependency parsing and co-occurrences with which association of the designated word to be disambiguated with previous polarities. Then, the second part computes a Bayesian belief network of these features along with their conditional probabilities which are used to disambiguate and compute sentiments. The performance of the proposed scheme is exhaustively tested on standard datasets and results clearly show the efficacy of the proposed scheme.
SPIO-Loaded Nanostructured Lipid Carriers for T2-weighted Magnetic Resonance Imaging of Hepatocarcinoma
Authors: Lu Chen-ying , Zhang Nan-Nan , Shu Gao-feng , Zhu Xiu-liang , Chen Min-jiang , Weng Qiao-you , Lin Xian-yao , Du Yong-zhong , Ji Jian-song , Yu Risheng 
Published: April 2020

Abstract
Background

The development of sensitive and specific MRI contrast agents for early diagnosis of hepatocellular carcinoma is highly demanded. Here, a peptide A54 (sequence: AGKGTPSLETTP) functionalized superparamagnetic iron oxide nanoparticles (SPIONs)-based magnetic nanostructured lipid carrier(A54-MNLC)as a hepatoma targeting negative magnetic resonance imaging (MRI) contrast agent was developed.
Results

Firstly, the A54 peptide functionalized PEGylated SA (A54-PEG-SA) was synthesized by the coupling reaction between A54 and NH2-PEG-SA. Then SPIONs-loaded MNLC(MNLC and A54-MNLC)were prepared by the solvent diffusion method. The A54-MNLC with a diameter of about 50 nm, and in vitro cell viability study revealed that the prepared A54-MNLC was cytocompatible in the given particles’ concentration ranges. The cellular uptake results indicated that A54-MNLC was able to be uptaken specifically by human hepatoma cell line (Bel-7402 cells) and also can be used as efficient probe for targeted MR imaging of cancer cells in vitro. The in vivo MR imaging experiments using an orthotopic implantation model further validated the hepatoma-targeting ability of A54-MNLC with a more remarkable MR imaging contrast effect compared to MNLC.
Conclusions

These results demonstrate that the A54-MNLC is a promising nanoplatform as a targeted MR imaging contrast agent for the diagnosis of hepatocellular carcinoma.
Expression characteristics of exosomal long non-coding RNA in abdominal aortic aneurysm
Authors: Li Chuang , Zhao Yubo , Wan Shuwei , Guo Yaming , Han Mingli , Zhang Shuai , Jiao Zhouyang , Xu Peng , Hua Zhaohui , Liu Shirui , Cao Hui , Li Zhen 
Published: April 2020

Abstract
Background and objective:Abdominal aortic aneurysm(AAA) is one of the important causes of morbidity and mortality in middle-aged and elderly people. Although the understanding of the physiology and pathology of AAA has been improved, the potential molecular mechanism of AAA is still unclear. The existing evidence confirms that exosomal lncRNAs have a wide range of biological functions, and its regulatory disorders are related to the occurrence of diseases such as AAA, but the internal mechanism is not clear. The main purpose of this study is to screen the differentially expressed lncRNAs in exosomes between normal people and patients with AAA and to understand its internal mechanism.Materials and methods:The plasma of a healthy control group and patients with abdominal aortic aneurysm was collected, and the lncRNAs of exosomes were extracted and sequenced. Differential expression was assessed by DEseq using read counts as input and chosen according to the criteria of |log2(fold change)| > 1 and adjusted p-value < 0.05. Based on the Kyoto encyclopedia of genes and genomes (KEGG) and biological pathway and gene ontology (GO) functional enrichment analysis, the target genes were analyzed, and the correlation between lncRNA and target genes was analyzed.Result:We screened 45 species differentially expressed lncRNAs and found pathway significantly related to these genes, namely metabolic pathways, calcium signaling pathways and protein processing in endoplasmic reticulum and They play a significant and important role in the metabolic process and the cell signaling.Conclusion:There was significant difference in expression of exosomal lncRNAs between normal subjects and AAA patients. LncRNAs in exosomes regulate in the progress of AAA by activating metabolic pathway and calcium signaling pathway, but the specific mechanism is not clear and needs to be further explored.