bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Process of Injection Drug Use Among Homeless Women:A Qualitative Study
Authors: Kitson Cynthia , O'Byrne Patrick 
Published: April 2020

Abstract
Background: The literature on women who use injection drugs (WUID) is antiquated and diluted by data from men. Due to the higher rates of morbidity and mortality among WUID, we undertook a qualitative study to better understand their drug use practices. Methods: We adopted a Deleuzo-Guattarian lens and engaged in semi-structured interviews with 35 women. Data were analyzed applied thematic analysis. Results: We divided these themes into (1) how WUID obtain resources to acquire drug, and (2) the steps involved in preparing, using, and discarding drugs. From our Deleuzo-Guattarian perspective, these findings highlighted that participants stratified their worlds according to rules of cleanliness to create hierarchies of appropriateness and acceptability. Conclusions: These findings, overall, highlight the importance of understanding the constructed world of women who use injection drugs, particularly regarding the ways by which nurses interact with these women to provide care.
Patient with COVID-19 who has no specific onset symptoms and progresses rapidly to death: a case report
Authors: Fang Lei , Zhang Shuaipan , Cheng Wei , Zhan Chao , Fang Xiaoming 
Published: April 2020

Abstract

BackgroundSince its outbreak, COVID-19 has continued to spread rapidly more than 3 months, which constituted a public health emergence worldwide.The onset symptoms of patients with COVID-19 are not specific, especially in non-respiratory symptoms, it is easy to be ignored, which can cause widespread infection. For critically ill patients, glucocorticoids are used for anti-inflammatory treatment. However, after the application cycle recommended by the guidelines, the deterioration of the patient's condition and treatment to suppress cytokine storms is more critical.Case presentationA previous patient was admitted to the hospital due to abdominal pain and diarrhea, and accidentally was confirmed with positive SARS-CoV-2. The patient progressed rapidly from mild to severe within 2 days of admission. With timely anti-viral and anti-inflammatory drugs and early ventilator respiratory support, the patient's condition improved temporarily, and subsequently accompanied by a decrease in glucocorticoids, the patient's condition worsened and eventually died. Her family members were also hospitalized due to close contact.ConclusionThis case highlights that even if glucocorticoids are discontinued in accordance with the guidelines, deterioration of the patient's condition is inevitable attribute to the cytokine storms. And related Chinese and western medicines that suppress cytokine storms should be applied in time. In addition, more systematic epidemiological surveillance and stool tests are necessary due to potential lethal risk and route of transmission.
Therapeutic targeting of coronavirus spike glycoprotein priming
Authors: Pellecchia Maurizio , Barile Elisa , Baggio Carlo , Gambini Luca , Shiryaev Sergey A. , Strongin Alex Y. 
Published: April 2020

Abstract

Processing of certain viral proteins and bacterial toxins by host serine proteases is a frequent and critical step in virulence. The coronavirus spike glycoprotein contains three (S1, S2, and S2’) cleavage sites that are processed by human host proteases. The exact nature of these cleavage sites, and their respective processing proteases, can determine whether the virus can cross species, and the level of pathogenicity. Recent comparisons of the genomes of the highly pathogenic SARS-CoV2 and MERS-CoV, with less pathogenic strains (e.g., Bat-RaTG13, the bat homologue of SARS-CoV2) identified possible mutations in the receptor binding domain and in the S1 and S2’ cleavage sites of their spike glycoprotein. However there remains some confusion on the relative roles of the possible serine-proteases involved for priming. Using anthrax toxin as a model system, we show that in vivo inhibition of priming by pan-active serine protease inhibitors can be effective at suppressing virulence. Hence, our studies should encourage further efforts in developing either pan-serine protease inhibitors or inhibitor cocktails to target SARS-CoV2 and potentially ward off future pandemics that could develop because of the additional mutations in the S-protein priming sequence in coronaviruses.
NiFe2O4@SiO2 @amino Glucose Magnetic Nanoparticle under Solvent-free Condition: A New, mild, Simple and Effective Avenue for the Synthesis of Quinazolinone, Imidazo[1,2-a]Pyrimidinone and Novel Derivatives of Amides
Authors: Fekri Leila Z. 
Published: April 2020

Background:
Imidazo[1,2-a]pyrimidinone, quinazolinone and amide derivatives have attracted a lot
of interest because of their broad scope of biological and pharmacological activities. There are a lot of methods
reported in the literature for their synthesis. Therefore, we became interested in developing a convenient
synthetic method for the preparation of imidazoquinazolinone and amide derivatives.

Objective:
NiFe2O4@SiO2 @glucose amine were synthesized, characterized and have been used for the green,
effective and mild multicomponent synthesis of quinazolinones, benzoimidazo[1,2-a]pyrimidinones and
amides under solvent-free conditions in short reaction times and excellent yields. To expand of the scope of
this avenue, multicomponent synthesis of mono and bis novel amides was tested for the first time. All of the
products were characterized by mp, FT-IR, NMR and elemental analysis.

Methods:
Aldehyde (1mmol), 2-amino benzimidazole (1 mmol), dimedone (1mmol) or indane-1,3-dione (1
mmol) for the synthesis of quinazoline or imidazopyrimidinones and arene (1mmol), anhydride (1mmol), 2-
aminobenzimidazole (1mmol) for the synthesis of amides in the nanocatalyst NiFe2O4@SiO2@glucose amine
(0.15mol%: 0.05g) were stirred by a magnet for the required reaction time. After completion of the reaction, as
indicated by TLC, the products were collected and recrystallized from ethanol if necessary.

Results:
We present a novel avenue for the synthesis of benzimidazo[1,2-a] pyrimidinones, quinazolinones and
amides in the presence of NiFe2O4@SiO2@glucose amine under solvent-free conditions.

Conclusion:
In conclusion, we developed NiFe2O4@SiO2 @glucose amine-catalysed multicomponent
synthesis of quinazolinones and imidazo[1,2-a]pyrimidinones using the reaction of benzaldehyde, dimedone or
indane-dione and 2-aminobenzimidazole and multicomponent synthesis of amides using arenes, cyclic
anhydrides and 2-aminobenzimidazole by a solvent-free technique. This method proves to be a robust and
innovative approach for the synthesis of a biologically important structure. The operational simplicity, the
excellent yields of products, ease of separation and recyclability of the magnetic catalyst, waste reduction and
high selectivity are the main advantages of this method. Furthermore, this new avenue is cheap and
environmentally benign.
Penerapan Metode Learning Vector Quantization2 (LVQ 2) Untuk Menentukan Gangguan Kehamilan Trimester I
Authors: Budianita Elvia Budianita 
Published: April 2020

Trimester I adalah masa dimana 3 bulan pertama kehamilan yakni 0 sampai 12 minggu awal kehamilan. Pada masa ini tubuh ibu akan banyak mengalami perubahan seiring berkembangnya janin. Pada ibu-ibu hamil pada fase trimester I terkadang ditemukan beberapa gangguan kehamilan yaitu, Abortus, Anemia Kehamilan, Hiperemesis Gravidarum tingkat I, Hiperemesis Gravidarum tingkat II, Kehamilan Ektopik, dan Mola hidatidosa. Untuk membantu pasien dalam mengenali gangguan kehamilan pada trimester I ini maka peneliti berinisiatif merancang suatu sistem yang menerapkan konsep jaringan syaraf tiruan dengan metode LVQ 2 (Learning Vector Quantization) dalam mengenali gangguan kehamilan trimester I berdasarkan gejala gangguan kehamilan trimester I. Ada 41 gejala penyakit, dan 6 penyakit sebagai data masukan. Sistem akan mengklasifikasikan penyakit dengan proses pembelajaran dan pengujian ke dalam 6 jenis penyakit, berdasarkan pengujian metode LVQ2 cukup baik di terapkan dalam pengenalan pola gejala gangguan kehamilan, di buktikan dari hasil pengujian yang di lakukan menggunakan window 0.1, 0.3, 0.5, dan 0, data latih 90 dan data uji 18 didapat akurasi terbaik 100% dan rata-rata akurasi 97.68% dengan nilai parameter pembelajaran algoritma learning rate = 0.02, 0.04, 0.06, pengurangan learning rate = 0.1, minimal learning rate = 0.01 dan nilai window (ε) =0.1, 0.3, 0.5, dan 0. Nilai w juga mempengaruhi akurasi. Kata Kunci: Gangguan Kehamilan Trimester I, Learning Vector Quantization 2, Window
Morir por lo divino: Jan Patocka
Authors: Garrido-Maturano Ángel E. 
Published: April 2020

RESUMENEl artículo se ocupa de la cuestión de Dios y la muerte en el pensamiento de Patocka. Comienza analizando los dos primeros movimientos del mundo de la vida, para centrarse en el tercero: «el descubrimiento del sí». Luego procura mostrar cómo, a través de la divinización del tiempo al cual debemos sacrificar la propia vida, la filosofía de Patocka consuma la subordinación de la problemática ética al renovarse de la temporalidad como sentido del ser. En este contexto se analiza la relación entre la muerte como sacrificio por un lado y el ser, lo Divino y la temporalidad por el otro. PALABRAS CLAVE PATOCKA-DIOS-MUERTE-TIEMPO.ABSTRACTThe article is about God's question and death in Patocka's thought. It starts analysing the first two movements in the world of life, to focus on the third one: «the discovery of oneself». Then, it sets out to show how, throught time divinity, to wich we have to sacifice our own life, Patocka's philosophy consummates the subordination of the ethic problem when renewing the temporality as sense of being. In this context it is analysed the relationship between death and sacrifice, on one side, and divinity and temporality, on the otherKEYWORDSPATOCKA-GOD-DEATH-TIME
The Effect of The Aggregate Abrasion Value on The Aggregate Pore Content in The Base Layer above Base B
Authors: Putri Lusi Dwi , Soehardi Fitridawati 
Published: April 2020

Campuran lapisan pondasi bawah base B yang baik mempunyai persyaratan untuk agregat yang digunakan yaitu nilai abrasi kecil dari 40%, nilai berat jenis agregat minimum 2,5 dan penyerapan air agregat maksimum 3%. Hal ini sebagai syarat untuk menghindari degradasi dan disintegrasi agregat serta penyerapan air yang baik pada saat pencampuran, penghamparan, pemadatan maupun pada saat melayani lalu lintas selama umur rencana. Penelitian bertujuan untuk mengetahui pengaruh nilai abrasi terhadap nilai penyerapan air rongga pada campuran lapisan pondasi bawah base B dengan menggunakan 3 jenis quarry agregat. Penelitian ini menggunakan alat Los Angeles dan analisa saringan. Berdasarkan hasil pengujian diperoleh nilai abrasi paling baik adalah agregat quarry Solok yaitu 17,5 %, kemudian agregat quarry Pangkalan yaitu 23,7 % dan nilai abrasi yang kurang baik agregat quarry Bangkinang yaitu 34,58. Nilai penyerapan air agregat quarry paling tinggi adalah quarry Bangkinang kemudian quarry Pangkalan, dan nilai penyerapan paling kecil adalah quarry Solok. Hasil dari penelitian ini diharapkan dapat membantu pihak yang berkompeten dalam memberikan rekomendasi penggunaan material berdasarkan nilai abrasi dan nilai penyerapan air agregat.
Assessment of the phytoavailability of Cu and Ni using various extraction procedures
Authors: Chowdhury MTA , Nesa L , Huq SM Imamul 
Published: April 2020

The phytoavailability of copper (Cu) and nickel (Ni) in soils from Bangladesh was assessed. The uptake by Ipomoea aquatica and Oryza sativa L. was measured and a range of extractants tested on soils and plant tissue samples. Extractants tested were distilled water, 1 M NH4Cl, 0.01 M CaCl2, 0.005 M diethylenetriamine penta‐acetic acid (DTPA), 0.1 M ethylenediamine tetraacetic acid (EDTA), 0.1 M HCl and 1 M HCl. The extractability of the metals varied depending on the metal species, the crop and the extractant used. The best extractant was 1 M HCl, which extracted the highest amount of the heavy metals and correlated most strongly with their plant uptake measures. The use of 1 M HCl is, therefore, recommended for first‐level screening of soils contaminated with heavy metals if only one extractant is to be used. Sequential extraction showed that Cu was associated mostly with the 0.005 M DTPA and 0.1 M EDTA extractable fractions, while Ni was associated with the 0.1 M HCl and 1 M HCl fractions in most cases. The fractions of metals extracted using the sequential extraction procedure varied compared to single extractions for all soil types.
Dhaka Univ. J. Biol. Sci. 24(1): 1-16, 2015 (January)
Depression of married women: Exploring the role of employment status, marital satisfaction and psychological well-being
Authors: Islam Md Azharul , Efat Sayeda Amina , Yousuf Ayesha Binte , Islam Shaheen 
Published: April 2020

This study was carried out to explore the level of depression among married women. Additionally, the role of employment status, academic qualification, marital satisfaction and psychological well-being on depression was examined. Depression, marital satisfaction and psychological well-being of 200 married women were assessed. Results showed 15% of the study participants scored above the cut-off point of depression and are at the risk of depression. Employment and academic status, marital satisfaction and psychological wellbeing (GHQ-28) jointly accounted for 56.2% variability in the depression with psychological well-being (β = 0.515, p < 0.001) and marital satisfaction (β = –0.276, p < 0.001) appeared as the most influential predictors. Lower education and unemployment also associated with the higher level of depression. The model indicated if a married woman with poorer psychological well-being, lower marital satisfaction and lower educational qualification is unemployed, she is more likely to be diagnosed as depressed. Implications and future direction are discussed.
Dhaka Univ. J. Biol. Sci. 25(2): 113-121, 2016 (July)
16S rRNA sequence based identification of pathogenic gut microbiota of rohu Labeo rohita (Hamilton-Buchanan 1822) and silver carp Hypophthalmichthys molitrix (Valenciennes 1844)
Authors: Punom Nusrat Jahan , Hasan AKM Mahbub , Haque Wahida , Begum Mst Khadiza , Rahman Mohammad Shamsur 
Published: April 2020

Rohu (Labeo rohita) and Silver carp (Hypophthalmichthys molitrix) are the most common, popular and commercially important fish of Bangladesh. Pathogenic gastrointestinal bacteria indicate the acceptability or quality hence it influences the economic status of these fish. To investigate the pathogenic gastrointestinal bacteria of these economically important fish of Bangladesh was carried out. Gut microbiota of indigenous Rohu and exotic Silver carp of three different markets of Dhaka metropolitan city were studied using various selective agar media, classical biochemical tests and 16S rRNA sequencing. Antibiotic susceptibility of selected isolates was also carried out against 14 antibiotics. Firstly, 216 colonies were differentiated morphologically and among them, 18 isolates were characterized by biochemical properties. Finally, the identification of 10 isolates were confirmed by sequencing the 16S rRNA gene. Total bacterial count (TBC), total Salmonella-Shigella and total Staphylococcal count exhibited significant difference (p < 0.05) between the species but not among markets. TBC of Rohu samples was 5.27 ± 2.01 × 107 cfu/g and in Silver carp was 3.02 ± 1.42 × 107 cfu/g, total Salmonella and Shigella was 6.94 ± 7.15 × 106 cfu/g from Rohu and 1.11 ± 0.97 × 106 cfu/g from Silver carp. Total Staphylococcal count was found 1.03 ± 0.52 × 107 cfu/g in Rohu and 5.48 ± 3.98 × 106 cfu/g in Silver carp. Biochemical assays provisionally determined 7 different bacterial genera from Rohu and 7 from Silver carp. Six different genera of Gram-negative bacteria (4 genera from Rohu and 2 from Silver carp) were identified as Aeromonas, Proteus, Pseudomonas, Enterobacter, Citrobacter, Klebsiella sp. by 16S rRNA sequencing. The results revealed that all the 18 representative isolates including reference strain (E. coli DH5α) were sensitive to ciprofloxacin and resistant to sulphamethoxazole. These findings might be due to the poor quality of the aqueous environment and reflects fish as the potential reservoir of pathogenic bacteria causing fish-borne disease outbreaks.
Dhaka Univ. J. Biol. Sci. 25(2): 169-184, 2016 (July)
Growth performance and fatty acid profile of Nile tilapia Oreochromis niloticus (Linnaeus, 1758) fed with different phytoplankton
Authors: Hossain Md Babul , Sultana Nahid , Noor Parvin , Khan Selina , Lisa Sharmin Akter , Begum Mahmuda , Punom Nusrat Jahan , Begum Mst Khadiza , Hasan Md Rakibul , Rahman Mohammad Shamsur 
Published: April 2020

The effect of different phytoplankton species on growth, survival and fatty acids composition of Nile tilapia (Oreochromis niloticus) was evaluated for 24 weeks. Treatment-1 was fed with commercial feed as Control, treatment-2 was fed with Spirulina platensis, treatment-3 was fed with Chlorella vulgaris and treatment-4 was fed with mixed phytoplankton (Chlorella vulgaris, Spirulina platensis, Azolla pinnata and Pistia stratiotes). The condition factor of fish found in treatment-3 with Chlorella vulgaris (1.73 ± 0.02) was significantly higher than that of treatment-1 as control (1.56 ± 0.02) at 24 weeks culture period. The specific growth rate of treatment-4 with mixed phytoplankton diet (2.00 ± 0.10) was significantly higher than treatment-3 with Chlorella vulgaris (1.13 ± 0.05) after 24 weeks of rearing. There was no significant difference among the four treatments in case of average daily gain, feed conversion ration and survival rate. The use of different phytoplankton such as Spirulina platensis, Chlorella vulgaris and Azolla pinnata influence the fatty acid profiles of Nile tilapia. Findings also showed that the amount of eicosapentaenoic acid (EPA) in treatment-3 fed with Chlorella vulgaris (1.83 ± 0.22) was highly significant than the other treatments. The highest amount of docosahexaenoic acid (DHA) was found in treatment-1 fed with commercial feed (2.70 ± 0.53%) and lowest in treatment-2 with Spirulina platensis (0.06 ± 0.02%). Among 19 unsaturated fatty acid, the highest concentration of PUFAs were recorded in treatment-3 (42.55 ± 3.46%) fed with Chlorella vulgaris. The findings of this study suggest that raising Nile tilapia with Chlorella vulgaris and Spirulina platensis in ponds may improve the growth and fatty acid profile of the fish.
Dhaka Univ. J. Biol. Sci. 26(1): 13-27, 2017 (January)
Mycoflora associated with infected fruits of different varieties of Musa sapientum L. and their pathogenic potentiality
Authors: Ameen Md Al , Shamsi S , Bashar MA 
Published: April 2020

A total of 11 fungal species were isolated from the 25 infected fruit samples of three varieties (Sabri, Champa and Sagor) of Musa sapientum. The isolated fungi were Aspergillus flavus Link, A. fumigatus Fresenius, A. niger van Tiegh., Colletotrichum musae (Berk. & Curt.) Arx, Curvularia brachyspora Boedijn., Fusarium semitectum Berk. & Rav. Fusarium sp. Link, Penicillium sp., Pestalotiopsis disseminata (Thum) Steyaert, Rhizopus sp. Ehrenb. and Trichoderma viride Pers. ex Gray. Fusarium semitectum showed the highest (28.61) per cent association frequency in Sabri variety whereas Fusarium sp. showed the lowest (3.33). Curvularia brachyspora showed the highest (21.11) per cent frequency in Champa variety whereas A. fumigatus showed the lowest (2.78). Fusarium sp. showed the highest (41.67) per cent frequency in Sagor variety whereas T. viride showed the lowest (3.34). Among the isolated fungi C. musae, C. brachyspora, F. semitectum, Fusarium sp. and P. disseminata were found to be pathogenic to three banana varieties. The presence of Pestalotiopsis disseminata (Thum) Steyaert in Sabri variety of banana is the first record in Bangladesh.
Dhaka Univ. J. Biol. Sci. 26(1): 101-110, 2017 (January)
Living arrangements and social support as predictors of mental health and life satisfaction of older adults
Authors: Karmaker Chhanda , Hossain Afroza , Bakul Fariea , Raisa Sumaia Ali 
Published: April 2020

The aim of the present study was to investigate whether living arrangement and social support are significant predictors of mental health and life satisfaction among older adults. Data were collected by using convenience sampling technique from 300 older adults (100 living in old home and 200 living in their own home with spouse or children) of Dhaka and Gazipur districts. The instruments used for collecting data were: (1) Demographic and personal information questionnaire, (2) Bangla version of Social Support Scale, (3) Bangla version of General Health Questionnaire (GHQ-12) and (4) Bangla version of Satisfaction with life scale. The results of the current study indicated that the type of living arrangement has the most influence towards mental health (29.05%) and life satisfaction (30.91%) than social support. Older adults who live in own home have higher life satisfaction (M = 25.86) and less mental health problems (M = 32.55) than those living in old home (M = 17.78) and (M = 39.80). The result also revealed that older people living in old homes have higher social support (M = 51.73) than those who are living with children, spouses or other family relatives (M = 48.02)).
Dhaka Univ. J. Biol. Sci. 27(1): 17-25, 2018 (January)
Bacterial load and multi‐drug resistance patterns of some ready‐to‐eat street foods of Dhaka city
Authors: Saha Mihir Lal , Akter Mist Dilara , Khan Tahsin , Ansari Aneesa , Islam Mohammad Nurul 
Published: April 2020

Bacterial load and drug resistance pattern associated with some ready-to-eat (RTE) street foods such as Chatpoti, Fuchka, Singara, Panipuri, Ghugni-muri, Chola and water of Dhaka South City Corporation were investigated. Most of the samples were found to be contaminated and the bacterial load ranged from 2.4 × 104 - 9.2 × 106, 1.2 × 103 - 7.3 × 105 and 1.1 × 103 - 1.6 × 106 cfu/g of aerobic heterotrophic, coliform bacteria and Staphylococcus, respectively. The highest coliform load (7.3 × 105 cfu/ml) was found in the water of Gulistan. The highest aerobic heterotrophic bacteria (9.2 × 106 cfu/g) and Staphylococcus (1.6 × 106 cfu/g) were observed in the Chatpoti of Nilkhet. Among the isolated 100 different bacterial colonies, 20 Gram-positive and 8 Gram-negative isolates were studied in details. Based on the morphological and biochemical analysis, the Grampositive isolates were identified as Staphylococcus (9), Bacillus (4), Kurthia (3), Planococcus (1), Micrococcus (1), Listeria (1) and Renibacterium (1). Gram-negative isolates were identified as Klebsiella pneumoniae (3), Yersinia pestis (1), Y. pseudotuberculosis (1), Escherichia coli (1), Enterobacter aerogenes (1) and Plesiomonas shigelloides (1). The multi-drug resistance (MDR) pattern was found to be diverse. Among the MDR bacteria, Enterobacter aerogenes was found to be resistant against six common antibiotics. Plesiomonas shigelloides and Yersinia pestis were found to be resistant against five antibiotics. The multiple antibiotic resistant (MAR) indices of Gram-negative isolates ranged in between 22.22 and 66.67%. Conventionally identified five bacterial isolates with significant MAR indices were further identified with 16S rDNA sequencing and found to be as Enterobacter cloaceae Ecl1, Plesiomonas shigelloides CIFRI, Aeromonas sp. TIL_WAK_4, Aeromonas sp. 280 and Klebsiella pneumoniae KPS77. Conventional identification was found to be accurate for three isolates but the two Yersinia sp. were identified to be as Aeromonas sp. in 16S rDNA sequencing.
Dhaka Univ. J. Biol. Sci. 27(1): 27-36, 2018 (January)