bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Health Technologies in Multicomponent Primary Care Interventions: Systematic Review
Authors: Jimenez Geronimo , Matchar David , Koh Choon Huat Gerald , van der Kleij Rianne , Chavannes Niels H , Car Josip 
Published: November 2020

Background
Several countries around the world have implemented multicomponent interventions to enhance primary care, as a way of strengthening their health systems to cope with an aging chronically ill population and rising costs. Some of these efforts have included technology-based enhancements as one of the features to support the overall intervention, but their details and impacts have not been explored.

Objective
This study aimed to identify the role of digital/health technologies within wider multifeature interventions that are aimed at enhancing primary care, and to describe their aims and stakeholders, types of technologies used, and potential impacts.

Methods
A systematic review was performed following Cochrane guidelines. An electronic search, conducted on May 30, 2019, was supplemented with manual and grey literature searches in December 2019, to identify multicomponent interventions that included at least one technology-based enhancement. After title/abstract and full text screening, selected articles were assessed for quality based on their study design. A descriptive narrative synthesis was used for analysis and presentation of the results.

Results
Of 37 articles, 14 (38%) described the inclusion of a technology-based innovation as part of their multicomponent interventions to enhance primary care. The most commonly identified technologies were the use of electronic health records, data monitoring technologies, and online portals with messaging platforms. The most common aim of these technologies was to improve continuity of care and comprehensiveness, which resulted in increased patient satisfaction, increased primary care visits compared to specialist visits, and the provision of more health prevention education and improved prescribing practices. Technologies seem also to increase costs and utilization for some parameters, such as increased consultation costs and increased number of drugs prescribed.

Conclusions
Technologies and digital health have not played a major role within comprehensive innovation efforts aimed at enhancing primary care, reflecting that these technologies have not yet reached maturity or wider acceptance as a means for improving primary care. Stronger policy and financial support, and advocacy of key stakeholders are needed to encourage the introduction of efficient technological innovations, which are backed by evidence-based research, so that digital technologies can fulfill the promise of supporting strong sustainable primary care.
Analysis of 2D and 3D GPR responses in the Federal University of Paraná Forensic Geophysics Controlled Site – a Case Study
Authors: Canata Rafael Espindola , Fonseca Ferreira Francisco José , Rodrigues Borges Welitom , Salvador Fábio Augusto Da Silva 
Published: November 2020

ABSTRACT. In 2016, the Laboratory for Research in Applied Geophysics (LPGA), at the Federal University of Paraná, in partnership with the Federal Police of the State of Paraná and the University of Brasília built a Forensic Geophysics Controlled Site (FGCS-UFPR) to calibration of the applied geophysical method and strengthen forensic sciences in the State of Paraná. In the FGCS, several objects that simulate forensic, archaeological and paleontological targets were installed at extremely shallow depths. The materials were covered with clayey soil, typical of the region, and in some pits, fine sandy sediments were deposited. This study aims to verify the 2D and 3D responses of the ground penetrating radar (GPR) method applied to targets installed in the FGCS, in a post-precipitation period. In the acquisition of GPR data, a 700 MHz shielded antenna was used, with parallel 2D profiles and spaced 0.1 meters. The results indicated that the high clay content present in the soil, below 0.5 meters deep, caused a high attenuation of the electromagnetic signal and defined patterns of reflectors associated with the targets, excavations and the investigated environment. Thus, only targets with high electrical impedance were visualized in 2D and 3D GPR images.Keywords: ground penetrating radar, clay soil, targets, forensic sciences, archaeogeophysics. Análise dos resultados 2D e 3D de GPR no Sitio Controlado de Geofísica Forense da UFPRRESUMO. Em 2016, o Laboratório de Pesquisas em Geofísica Aplicada (LPGA), da Universidade Federal do Paraná, em parceria com a Polícia Federal do Paraná e a Universidade de Brasília, instalou um Sítio Controlado de Geofísica Forense (SCGF-UFPR) para a calibração do método geofísico aplicado e o fortalecimento das ciências forenses no Estado do Paraná. No SCGF foram instalados, em profundidades extremamente rasas, diversos objetos que simulam alvos forenses, arqueológicos e paleontológicos. Os materiais foram recobertos com solos argilosos, típicos da região, e em algumas cavas foram depositados sedimentos arenosos finos. Este estudo objetiva a verificação das respostas 2D e 3D do método radar de penetração no solo (GPR) aplicada aos alvos instalados no SCG, em um período pós-precipitação pluviométrica. Nas aquisições de dados de GPR foi aplicada a antena blindada de 700 MHz, com perfis 2D paralelos e equiespaçados em 0,1 metro. Os resultados indicaram que o alto teor de argila presente no solo, abaixo de 0,5 metro de profundidade, causou uma elevada atenuação do sinal eletromagnético e definiu-se padrões de refletores associados aos alvos, as escavações e ao meio investigado. Assim, apenas os alvos com alta impedância elétrica foram visualizados nas imagens GPR 2D e 3D.Palavras-chave: ground penetrating radar, solo argiloso, artefatos, ciência forense, arqueogeofísica.
Regression to the Mean Contributes to the Apparent Improvement in Glycemia 3.8 Years After Screening: The ELSA-Brasil Study
Authors: Schmidt Maria Inês , Bracco Paula , Canhada Scheine , Guimarães Joanna M.N. , Barreto Sandhi Maria , Chor Dora , Griep Rosane , Yudkin John S. , Duncan Bruce B. 
Published: November 2020

OBJECTIVE
Glycemic regression is common in real-world settings, but the contribution of regression to the mean (RTM) has been little investigated. We aimed to estimate glycemic regression before and after adjusting for RTM in a free-living cohort of adults with newly ascertained diabetes and intermediate hyperglycemia (IH).

RESEARCH DESIGN AND METHODS
The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a cohort study of 15,105 adults screened between 2008 and 2010 with standardized oral glucose tolerance test and HbA1c, repeated after 3.84 ± 0.42 years. After excluding those receiving medical treatment for diabetes, we calculated partial or complete regression before and after adjusting baseline values for RTM.

RESULTS
Regarding newly ascertained diabetes, partial or complete regression was seen in 49.4% (95% CI 45.2–53.7); after adjustment for RTM, in 20.2% (95% CI 12.1–28.3). Regarding IH, regression to normal levels was seen in 39.5% (95% CI 37.9–41.3) or in 23.7% (95% CI 22.6–24.3), depending on use of the World Health Organization (WHO) or the American Diabetes Association (ADA) definition, respectively; after adjustment, corresponding frequencies were 26.1% (95% CI 22.4–28.1) and 19.4% (95% CI 18.4–20.5). Adjustment for RTM reduced the number of cases detected at screening: 526 to 94 cases of diabetes, 3,118 to 1,986 cases of WHO-defined IH, and 6,182 to 5,711 cases of ADA-defined IH. Weight loss ≥2.6% was associated with greater regression from diabetes (relative risk 1.52, 95% CI 1.26–1.84) and IH (relative risk 1.30, 95% CI 1.17–1.45).

CONCLUSIONS
In this quasi–real-world setting, regression from diabetes at ∼4 years was common, less so for IH. Regression was frequently explained by RTM but, in part, also related to improved weight loss and homeostasis over the follow-up.
Los senderos del cardo
Authors: Valbuena Jorge 
Published: November 2020

Jorge Valbuena (Facatativá, 1985) es magister en estudios de la cultura (Universidad Andina Simón Bolívar). Forma parte de La Raíz Invertida. Revista Latinoamericana de Poesía. Es autor de los poemarios La danza del caído, Pasajera de agua y Árbol del navío.
La fracasada búsqueda de El Dorado, origen de Nueva Granada
Authors: Camargo Cortés Vivian 
Published: November 2020

En Elegías de varones ilustres de Indias (1589), Juan de Castellanos deconstruye el mito de El Dorado y realiza una crítica tanto a la avaricia de los españoles como a su falta de criterio para adentrarse en un territorio que no fue previamente estudiado. Las elegías se centran en la propuesta de pacificación ejercida por Don Gonzalo para instaurar la Nueva Granada, decisión que iba a permitir la consolidación de ciudades y reinos. Además, Castellanos cuestiona el origen del mito por no ser comprobable y por haberse propagado y deformado a lo largo del tiempo.
Serial changes in serum phosphorylated neurofilament and value for prediction of clinical outcome after traumatic brain injury
Authors: Otani Naoki , Morimoto Yuji , Kinoshita Manabu , Ogata Toru , Mori Kentaro , Kobayashi Masato , Maeda Takeshi , Yoshino Atsuo 
Published: November 2020

Background:
Phosphorylated neurofilament heavy subunit (pNF-H) is a constituent protein of the nerve axon, which leaks into the peripheral blood in various central nervous disorders. This study examined the time course of pNF-H value up to 1 month after injury and investigated the correlation with clinical outcome.

Methods:
Serum pNF-H concentration was measured on admission, and at 24 h, 72 h, 1 week, 2 weeks, and 1 month after injury in 20 patients, 15 males and 5 females aged 35–68 years (mean 52 years), with traumatic brain injury (TBI) transported to our hospital between April 2016 and March 2017. The clinical outcome at discharge was evaluated by Glasgow Outcome Scale.

Results:
The pNF-H value showed no increase in patients without brain parenchymal injury, but pNF-H value increased depending on the severity of brain damage. pNF-H value peaked at 2 weeks after injury. Two patients with peak value exceeding 10,000 unit had very severe injury and died during hospitalization. Peak pNF-H value was 3210 ± 1073 unit in 12 patients with good outcome and 9884 ± 2353 unit in 8 patients with poor outcome (P = 0.0119).

Conclusion:
Serum pNF-H level tended to increase and peak at 2 weeks after injury, and the peak pNF-H value was correlated with clinical outcome after TBI. The temporal profile of blood pNF-H seems to be useful to predict the clinical outcome after TBI.
PROFESSIONAL SELF-DETERMINATION OF GRADUATES OF AN EDUCATIONAL ORGANIZATION AS A FACTOR OF PERSONAL DEVELOPMENT
Authors: Сетраков Александр Николаевич 
Published: November 2020

Рассматриваются особенности профессиональных ценностных ориентаций современных старшеклассников на этапе профессионального самоопределения. Определена сущность профессионального самоопределения, проблема и способы ее разрешения, факторы успешного осуществления. Раскрыты современные требования к процессу профессиональной ориентации старшеклассников в школе. Представлены основные подходы профессиональной ориентации школьников. Определена сущность профессионального самоопределения, проблема и способы ее разрешения, факторы успешного осуществления профессионального роста.
The features of professional value orientations of modern high school students at the stage of professional self-determination are considered. The essence of professional self-determination, the problem and ways of its solution, factors of successful implementation are determined. The modern requirements for the process of vocational guidance of high school students are revealed. The main approaches to vocational guidance of schoolchildren are presented. The essence of professional self-determination, the problem and ways of its solution, factors of successful implementation of professional growth are determined.
Seasonal habitat selection of cougars Puma concolor by sex and reproductive state in west‐central Alberta, Canada
Authors: Smereka Corey A. , Frame Paul F. , Edwards Mark A. , Frame Delaney D. , Slater Owen M. , Derocher Andrew E. 
Published: November 2020

Resource selection studies are commonly used to assess the landscape features that animals select or avoid in their environment. Selection for certain landscape features and landcover types may vary by sex and reproductive status of an individual, and habitat selection studies should incorporate these factors. Cougars Puma concolor are a wide‐ranging species that live in a diversity of habitats with varying levels of human disturbance. Geographic positioning satellite telemetry collars were deployed on 55 males, single females and females with kittens. We used a two‐stage resource selection function to assess the seasonal habitat characteristics used by adult cougars in west‐central, Alberta, Canada, near the northern extent of the species range, from 2016 to 2018. A latent selection difference function was used to compare differences in habitat selction between groups. All groups selected for similar habitat types including edge habitat, close proximity to water, sloped terrain, forested habitat and avoided roads. During the summer, close proximity to water and wetland land cover were among the most selected features for all groups. Forest and edge habitats also were important for single females and males. During the winter, forested habitat was one of the most important covariates for all groups along with close proximity to water, edge habitat and slope for single females and males. Selection for slope and avoidance of open agricultural land were among the most important for females with kittens. Our results provide insights into those landscape variables that are important for cougars at the northern extent of their geographical range.
Terapi Obat pada Pasien Diabetes Mellitus dengan Komplikasi di Rumah Sakit
Authors: Totong Julia , Ningsih Desi Wahyu 
Published: November 2020

Pengendalian Diabetes mellitus dilakukan dengan memperbaiki pola makan , kebiasaan aktivitas fisik/olahraga, konumsi obat dan edukasi. Terdapat hubungan yang erat antara hiperglikemia, resistensi insulin dan gangguan availabilitas nitritoksida endotel vaskuler. Kerusakan endotel akan menyebabkan terbentuknya lesi aterosklerosis koroner yang kemudian berujung pada penyakit kardiovaskuler (CVD). Hampir 50% total kematian pada DM tipe 2 karena CVD meningkatkan resiko kematian .
Metformin merupakan terapi lini pertama pada pasien diabetes melitus dengan CVD. Kombinasi metformin dengan obat golongan lainnya untuk mencapai kontrol glikemik dapat dilakukan dengan memperhatikan efek samping obat dan komorbiditas. Terapi yang efektif diperlukan untuk menurunkan resiko kejadian kardiovaskular, terutama infark miokard, CAD, stroke , CVD, CHF.
Aspirin tidak direkomendasikan pada pasien diabetes tanpa CVD atau kerusakan organ lainnya (resiko kardiovaskular rendah), terapi antiplatelet diberikann secara personalized pada pasien diabetes dengan risiko kardiovaskular tinggi. Stratifikasi risiko kardiovaskuler pada pasien diabetes ( rendah, tinggi atau sedang) tidak begitu penting , karena bila diagnosis diabetes sudah ditegakkan, sebab sudah terdapat risiko kardiovaskuler yang tinggi , sehingga sebaiknya pasien diabetes tanpa CAD juga mendapatkan terapi yang sama dengan pasien yang diabetes dengan CAD.
Terapi statin bertujuan menurunkan kadar LDL pada pasien diabetes dengan CVD.
Identifikasi dan Penetapan Kadar Rhodamin B pada Eye Shadow secara Kromatografi Lapis Tipis dan Spektrofotometri Ultraviolet-Visible
Authors: Fauziah Siva , Komarudin Dede , Dewi Citra 
Published: November 2020

Abstract
Based on BPOM findings in 2016 there is still the presence of Rhodamin B which is used as one of the dyes in cosmetics. It causes irritation to the skin, respiratory tract and is carcinogenic. The purpose of this study to conduct an examination and determination of Rhodamin B in eye shadow in the Kalideres traditional market. The sample used for the research is eye shadow that is bought from cosmetics stores and cosmetic kiosks, which circulated in the Kalideres traditional market. The sample consist of five different brands based on three criteria is eye shadow which does not include the ingredients used, the writing in the packaging used a language other than Indonesia and does not have a permit number from BPOM. This research was conducted to identify the presence of Rhodamin B in eye shadow with KLT method ( thin layer chromatography), the eluent used is N-butanol, etil asetat, amoniac 25% (10 : 4 : 5) then detected with UV light 254 nm and determination of the content using UV-Vis spectrophotometry method at maximum wavelength 553 nm using as blank is methanol. The resulted was presence of Rhodamine B in sample code A and sample code D with the average value of Rhodamine B levels in the sample examined, the sample code A is 1,3063 mg/g and sample code D is 1,2564 mg/g.

Keywords: Rhodamine B, Eye Shadow, KLT, Uv-Vis Spectrophotometry
Pengaruh Peran Orang Tua, Peran Program Generasi Berencana, Pertahanan Diri dan Sumber Informasi terhadap Perilaku Pencegahan Seks Pranikah pada Remaja
Authors: Sisilia Sisilia , Rindu Rindu 
Published: November 2020

Keberhasilan sebuah bangsa di masa yang akan datang sangat ditentukan oleh kualitas remaja pada masa sekarang, oleh karena itu masa remaja perlu mendapatkan perhatian dan pengawasan khusus, agar remaja memiliki kualitas yang optimal. Tujuan penelitian ini adalah untuk mengetahui pengaruh peran orang tua, peran program GenRe (Generasi Berencana), pertahanan diri dan sumber informasi terhadap perilaku pencegahan seks pranikah pada remaja di SMAN 02 Dedai Kabupaten Sintang 2019. Metode penelitian menggunakan analisis pendekatan cross sectional. Populasi pada penelitian ini adalah siswa/i SMAN 02 Dedai Kabupaten Sintang yang berjumlah 90 orang. Data yang dikumpulan adalah data primer, pengambilan sampel dengan teknik accidental sampling. Dari hasil analisis didapatkan nilai peran orang tua (0,020<0,05), peran program GenRe (0,006<0,05), pertahanan diri (0,013<0,05), dan sumber informasi (0,012<0,05), dapat disimpulkan dari hasil analisis ada hubungan yang signifikan antara peran orang tua, peran program GenRe, pertahanan diri dan sumber informasi dengan perilaku pencegahan seks pranikah pada remaja. Hasil uji multivariat didapatkan dari hasil uji regresi logistik peran orang tua (0,010 <0,05), peran program GenRe (0,003<0,05), pertahanan diri (0,007<0,05) dan sumber informasi (0,006<0,05) berpengaruh terhadap perilaku pencegahan seks pranikah pada remaja. Dari penelitian ini dapat disimpulkan bahwa memberikan bimbingan sejak dini kepada anak sangat penting tidak hanya tugas orang tua tetapi pihak yang memahami akan kesehatan reproduksi juga harus turut berkontribusi agar para remaja memilki kualitas yang optimal.

Kata kunci : Remaja, Perilaku, Pencegahan Seks Pranikah
Contributing Factors and Evolution of Impulse Control Disorder in the Luxembourg Parkinson Cohort
Authors: Binck Sylvia , Pauly Claire , Vaillant Michel , Hipp Geraldine , Gantenbein Manon , Krueger Rejko , Diederich Nico J 
Published: November 2020

Background: To establish the frequency of impulse control disorder (ICD) in Parkinson's disease (PD).Methods: Within the Luxembourg Parkinson's Study, PD patients were evaluated for ICD presence (score ≥ 1 on MDS-UPDRS I item 1.6), use of dopamine agonists (DA) and other medications.Results: 470 patients were enrolled. Among 217 patients without DA use, 6.9% scored positive for ICD, vs. 15.4% among 253 patients with DA use (p = 0.005). The regression analysis showed that age at PD diagnosis had only a minor impact on ICD occurrence, while there was no influence by gender or co-medications. The longitudinal study over 2 years in 156 patients demonstrated increasing ICD frequency in DA users (p = 0.005).Conclusion: This large and non-interventional study confirms that PD patients with DA treatment show higher frequency of ICD than patients without DA use. It newly demonstrates that ICD can develop independently from age, gender, or co-medications.
Teoría del delito en el sistema procesal penal acusatorio
Authors: Villacis Londoño Henry 
Published: November 2020

Se tiene por objetivo analizar cómo aplicar la teoría del delito en el sistema procesal penal acusatorio. Se trabajó con una metodología de tipo descriptiva documental con un diseño bibliográfico, lo que permitió investigar en fuentes bibliográficas y jurídicas, permitiendo articular un cuerpo reflexivo teórico como aporte al fortalecimiento del estado del arte del derecho. Entre los principales aportes se presenta que todo lo manifestado en líneas precedentes, podremos colegir que en el sistema adversarial en el campo del litigio del juicio-, si no se tiene una estrategia previamente elaborada, no se podrá llegar a un objetivo específico; pues el improvisar la defensa en el momento, nos llevaría a la mediocridad, desnaturalizando nuestra misión de abogado. Es muy difícil, en audiencia de juicio, poder escoger en ese momento la dogmática penal a implementar; interrogar sin conocer las respuestas y plantear alegatos sin saber que queremos demostrar.
Una mirada a la culpabilidad de las personas naturales en el Código Orgánico Integral Penal
Authors: Muñoa Vidal Tania 
Published: November 2020

Se realiza una revisión sobre la culpabilidad, como categoría dogmática que se funde en la Teoría del Delito; y, que se asume por la codificación penal ecuatoriana, sobre los escenarios de la responsabilidad penal, de la imputabilidad y del conocimiento de la antijuridicidad; lo que se contextualiza a partir de las causas de inculpabilidad que se prevén y determinan como el trastorno mental, la edad en personas menores de 18 años de edad, y la responsabilidad en caso de embriaguez o intoxicación.
Opening Pandora’s Box: Peeking inside Psychology’s data sharing practices, and seven recommendations for change
Authors: Towse John N. , Ellis David A , Towse Andrea S 
Published: November 2020

AbstractOpen data-sharing is a valuable practice that ought to enhance the impact, reach, and transparency of a research project. While widely advocated by many researchers and mandated by some journals and funding agencies, little is known about detailed practices across psychological science. In a pre-registered study, we show that overall, few research papers directly link to available data in many, though not all, journals. Most importantly, even where open data can be identified, the majority of these lacked completeness and reusability—conclusions that closely mirror those reported outside of Psychology. Exploring the reasons behind these findings, we offer seven specific recommendations for engineering and incentivizing improved practices, so that the potential of open data can be better realized across psychology and social science more generally.