bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic Value of 6-Minute Walk Distance in Patients Undergoing Percutaneous Coronary Intervention: a Veterans Affairs Prospective Study
Authors: Dasari Tarun W. , Patel Bhavin , Wayangankar Siddharth A. , Alexander David , Zhao Yan D. , Schlegel JoAnn , Leung Cheuk , Lozano Pedro , Latif Faisal , Thadani Udho 
Published: February 2020

The 6-minute walk distance (6MWD) test is a useful prognostic tool in chronic heart failure. Its usefulness after percutaneous coronary intervention is unknown.
In a prospective observational study, patients underwent a 6MWD test within 2 weeks after percutaneous coronary intervention. The primary endpoint was major adverse cardiovascular events (MACE) (death, acute coronary syndrome, and heart failure admission) at one year. Receiver operating characteristic curves and area under the curve were used to determine the 6MWD test's predictive power, and the Youden index was used to measure its effectiveness.
A total of 212 patients were enrolled (98% men; mean age, 65 ± 9 yr). Major comorbidities were hypertension in 187 patients (88%), dyslipidemia in 186 (88%), and diabetes mellitus in 95 (45%). Among the 176 patients (83%) who completed the 6MWD test, the incidence of MACE at one year was 22% (acute coronary syndrome in 17%; heart failure admission in 4%; and death in 3%). The area under the curve for MACE was 0.59, and 6MWD was shorter for patients with MACE than for those without (290 vs 326 m; P=0.03). For 39 patients with previous heart failure who completed the 6MWD test, the area under the curve was 0.64 for MACE and 0.78 for heart failure admission.
The 6MWD test predicted reasonably well the incidence of MACE one year after percutaneous coronary intervention. In a subgroup of patients with previous heart failure, it fared even better in predicting heart failure admission. Larger studies are needed to confirm these findings.
Modified Pull-Through Technique for Cardiac Resynchronization Therapy Upgrades in Patients with Occluded Access Veins
Authors: Imnadze Guram , Awad Khaled , Kranig Wolfgang , Giorgberidze Irakli 
Published: February 2020

The number of procedures for upgrading implantable devices for cardiac resynchronization therapy has increased considerably during the last decade. A major challenge that operators face in these circumstances is occlusion of the access vein. We have modified a pull-through method to overcome this obstacle.
Six consecutive patients with occluded access veins and well-developed collateral networks underwent a procedure in which the occluded vein was recanalized by snaring the existing atrial lead via transfemoral access. Upgrading the device was successful in all patients; none had intraprocedural complications. Our experience shows that our modified pull-through technique may be a feasible alternative for upgrading cardiac resynchronization therapy in patients with venous occlusion.
Molecular dynamics simulation of sI methane hydrate under compression and tension
Authors: Wang Qiang , Tang Qizhong , Tian Sen 
Published: February 2020

AbstractMolecular dynamics (MD) analysis of methane hydrate is important for the application of methane hydrate technology. This study investigated the microstructure changes of sI methane hydrate and the laws of stress–strain evolution under the condition of compression and tension by using MD simulation. This study further explored the mechanical property and stability of sI methane hydrate under different stress states. Results showed that tensile and compressive failures produced an obvious size effect under a certain condition. At low temperature and high pressure, most of the clathrate hydrate maintained a stable structure in the tensile fracture process, during which only a small amount of unstable methane broke the structure, thereby, presenting a free-motion state. The methane hydrate cracked when the system reached the maximum stress in the loading process, in which the maximum compressive stress is larger than the tensile stress under the same experimental condition. This study provides a basis for understanding the microscopic stress characteristics of methane hydrate.
Questions of Space in Contemporary Hollywood Cinema
Authors: Trinder Stephen 
Published: February 2020

AbstractSpatial fixing was an integral part of maintaining imperial power structures throughout the colonial period, and like other discourses, it later found itself reproduced in cinema. As such, the physical and mental use of space has become key to the dissemination of ideological messages in many films. Confronting this tendency, this study applies theories of postcolonialism to selected examples of contemporary Hollywood film to examine how far it reconstructs traditional binaries of space. This investigation finds that despite attempts to disseminate more culturally sensitive and globally-minded portrayals of the Other, space remains particularly problematic. It also remains vital to storytelling narratives of race, gender, class and society in consideration of the film cases analysed in this study. While Fanonian notions of space continue to permeate cinema—with Total Recall and Avatar in particular drawing upon stereotypical motifs, it is possible to observe developments upon these discourses. Elysium and District 9 exemplify this, with each feature employing space to address increased questioning of US cultural superiority since the failed Iraq and Afghanistan invasions and the 2008 global economic crash.
Co-design with Children: Using Participatory Design for Design Thinking and Social and Emotional Learning
Authors: Paracha Samiullah , Hall Lynne , Clawson Kathy , Mitsche Nicole , Jamil Fatima 
Published: February 2020

Abstract
This paper discusses leveraging design thinking techniques for involving children in serious game design in Japanese elementary schools. Our action research project approach accomplished two different goals: (1) to inculcate design thinking in pupils, and (2) to sensitize children on bullying victimization. Our approach uses a range of participatory design methods to distil design ideas from children and to support their design thinking aiming to boost children’s creative confidence and develop social and emotional skills. Key findings from our project are: (1) children made valuable design contributions including realistic bullying scenarios, language content, user interface design, storyline progression, character profiles, coping strategies etc., and (2) participatory design and design thinking stimulated ethical reasoning, reflection and empathy in children on bullying victimization. Our approach is unique in the current design thinking landscape, because it moves from designing “thing” (object) to designing “think” (bullying sensitization). Future research should focus on highlighting ways how participatory design and design thinking enrich and complement each other. The significance of our paper stems from the simple standpoint that those participating in a design should gain from participating in the design process. Takeaways for practitioners are: (1) building relationships with stakeholders, especially children, (2) empathy and user research techniques, (2) translating field data into usable insights, (3) idea-generation and rapid concept development, (4) product co-prototyping, (5) user engagement and co-creation, (6) multiple perspectives on effective communication.
Undiagnosed pheochromocytoma presenting as a pancreatic tumor: A case report
Authors: Legocka Malgorzata Emilia , Toutounchi Sadegh , Pogorzelski Ryszard , Krajewska Ewa , Celejewski Krzysztof , Galazka Zbigniew 
Published: February 2020

AbstractPheochromocytoma is a rare catecholamine-producing tumor of the adrenal gland. Patients with known pheochromocytoma undergoing surgery require preoperative treatment with alpha-blockers to reduce the risk of intraoperative complications related to catecholamine release. If undiagnosed, pheochromocytoma can lead to life-threatening surgical complications. We report the case of a patient with a suspected solid pseudopapillary neoplasm in the pancreatic tail, for whom pancreatoduodenectomy was scheduled. However, shortly after abdominal incision, hypertensive crisis developed and was followed by severe hypotension requiring intravenous vasopressors, which prompted discontinuation of the operation. Further diagnostic evaluation revealed marked elevations in urinary excretion of methylated catecholamines and suggested that the tumor was in fact a pheochromocytoma extending from the left adrenal gland. After preoperative treatment with doxazosin, the patient underwent lateral transperitoneal laparoscopic adrenalectomy, with no major complications and an uneventful postoperative course. The pathological report confirmed a diagnosis of pheochromocytoma. Due to the potential for life-threatening surgical complications in patients with pheochromocytoma not treated preoperatively with alpha-blockers, this tumor type should be included in the differential diagnosis of abdominal tumors of unknown origin.
Ultralow power demand in fluorescence nanoscopy with digitally enhanced stimulated emission depletion
Authors: Wang Luwei , Chen Yue , Peng Xiao , Zhang Jia , Wang Jialin , Liu Liwei , Yang Zhigang , Yan Wei , Qu Junle 
Published: February 2020

Abstract
Stimulated emission depletion (STED) microscopy breaks the optical diffraction barrier and has become a powerful tool for biological study. However, its application for in vivo study is limited because of its high demand for depletion power. Here, we propose digitally enhanced STED (DE-STED) as a method for reducing the depletion power that is required for STED superresolution imaging. A donut image is the key in this approach, which is composed of the depleted photons by STED laser and represents the intensity difference between confocal and STED images from the same imaging position. The depletion efficiency is digitally enhanced by multiplying the intensity of the donut image with a factor greater than 1, and then the photons from the periphery of the diffraction-limited spot are fully depleted by subtracting the enhanced donut image from the original confocal image. Finally, DE-STED achieves a resolution of ~λ/8 in biological samples with a depletion power that is an order of magnitude lower than that in traditional STED imaging. Furthermore, the proposed method helps to relax the restrictions on the fluorophore because of its low phototoxicity and photobleaching.
Energy Demands in Well-Trained Alpine Ski Racers During Different Duration of Slalom and Giant Slalom Runs
Authors: Bottollier Valentin , Coulmy Nicolas , Le Quellec Loïc , Prioux Jacques 
Published: February 2020

Abstract
Bottollier, V, Coulmy, N, Le Quellec, L, and Prioux, J. Energy demands in well-trained alpine ski racers during different duration of slalom and giant slalom runs. J Strength Cond Res 34(8): 2156–2164, 2020—The purpose of this study was to investigate the energy demands of different duration slalom (SL) and giant slalom (GS) events in well-trained alpine ski racers. Eight well-trained alpine ski racers (age: 18.2 ± 0.8 years; stature: 1.72 ± 0.10 m; body mass: 65.8 ± 12.0 kg) performed an incremental laboratory test on cycle ergometer and 4 standardized alpine ski runs: short (ST) and long (LG) versions of SL and GS (SLST, SLLG, GSST, and GSLG). Oxygen uptake (V̇o
2) and heart rate (HR) were recorded continuously in all conditions. Blood lactate ([La]) was determined immediately before run and 3 and 5 minutes after run ([La]peak). The contribution of aerobic, glycolytic, and phosphagen energy systems was estimated. The aerobic system was the primary energy system involved in GSST (43.9 ± 5.7%) and GSLG (48.5 ± 2.5%). No significant difference in the contribution of aerobic and glycolytic systems was observed in SLST and SLLG. [La]peak was higher in SLLG (11.10 ± 2.41 mmol·L−1) than in GSST (8.01 ± 2.01 mmol·L−1). There was no difference in oxygen uptake peak between GSST and GSLG. Energetic training goals should focus on the improvement of both aerobic, glycolytic, and phosphagen systems for alpine ski racers who perform SL and GS. Giant slalom specialists might benefit from emphasizing the improvement of the aerobic system, without neglecting other systems.
Hyperventilation-Aided Recovery for Extra Repetitions on Bench Press and Leg Press
Authors: Sakamoto Akihiro , Naito Hisashi , Chow Chin Moi 
Published: February 2020

Abstract
Sakamoto, A, Naito, H, and Chow, CM. Hyperventilation-aided recovery for extra repetitions on bench press and leg press. J Strength Cond Res 34(5): 1274–1284, 2020—Hyperventilation (HV)-induced alkalosis, an ergogenic strategy, improved repeated pedaling sprint performance through enhanced H+ removal. However, it did not confer beneficial effects on other forms of exercises. This study investigated the benefits of HV-aided recovery on lifting repetitions and joint velocity during resistance training involving multiple joints and both concentric and eccentric contractions. Eleven power-trained men (mean ± SD age: 22.5 ± 4.3 years, training experience: 8.3 ± 3.6 years) performed 6 sets each of bench press and leg press at 80% 1 repetition maximum. Each set was continued until failure, with a 5-minute recovery between sets. In protocol A, HV was implemented for 30 seconds before the first, third, and fifth sets of each exercise (HV-aided recovery), whereas spontaneous breathing continued throughout the recovery before the second, fourth, and sixth sets (control recovery). In protocol B, the order of the HV and control recoveries was reversed. For both protocols, reductions in repetitions (range: −4.7% to −22.5%) and velocity (range: −23.1% to −37.7%) were consistently observed after control recovery (p < 0.05), whereas HV-aided recovery resulted in increased repetitions (range: +21.3% to +55.7%) and velocity (range: +6.3% to +15.3%) (p < 0.05) or no reductions in these measures from the previous set. The total repetitions performed across 6 sets (protocols A and B combined) were greater after the HV-aided than control recovery (p ≤ 0.001) in bench press (44 ± 10 vs. 36 ± 10 reps, increased by 27.1 ± 24.1%) and leg press (64 ± 9 vs. 50 ± 15 reps, increased by 35.2 ± 29.5%). Hyperventilation-aided recovery may boost the effectiveness of resistance training through increased training volume and lifting velocity.
Privacy-Preserving Data Mining for Smart Manufacturing
Authors: Hu Qianyu , Chen Ruimin , Yang Hui , Kumara Soundar 
Published: February 2020

Abstract
Internet of Things (IoT) and data mining techniques have laid the foundation for the next generation of smart and secure manufacturing systems where big data are leveraged to extract useful information about the manufacturing processes and further help optimize decisions. The threat of data breach exists especially for nonpersonal, yet sensitive data, which are pertinent to every aspect of manufacturing. Data breach and privacy leakages can significantly impede the manufacturer’s business and lead to damaging a company’s reputation. With a comprehensive case study in the manufacturing setting, we show that adversaries can utilize accessible shop floor predictive models and other available background information to make inferences about sensitive attributes that were used as inputs to the original model and use that information for their own purposes. From this view, this article presents a privacy-preserving data mining framework to build a smart and secure manufacturing system. First, we introduce differential privacy (DP), an emerging approach to preserve the individual’s privacy in the data mining process. Second, we present a privacy-preserving system where DP mechanisms and queries are enforced to obtain differentially private results. Third, we propose to optimize the selection of DP mechanisms and privacy parameters by balancing the model utility and the robustness to attack. Further, we evaluate and validate the proposed privacy-preserving data mining framework with a real-world case study on the modeling of cutting power consumption in computer numerical control turning processes. Experimental results show that the performance gain, i.e., the trade-off between model utility and the robustness to attack, is improved from the nonprivate model by 5.6, 9.4, and 13.1 % for privacy-preserving Laplace, Gaussian, and sensitive mechanisms, respectively. This article is among the first to investigate and present a privacy-preserving data mining framework for smart manufacturing. The proposed methodology shows great potential to be generally applicable in industry for data-enabled smart and sustainable manufacturing.
ВЗАИМОДЕЙСТВИЕ УДАРНЫХ ВОЛН С ГОРНЫМИ ВЫРАБОТКАМИ
Authors: Луговoй П. З. , Гребенюк Т. В. 
Published: February 2020

Теоретическое моделирование взаимодействия ударных волн с горными выработками весьма актуально в горном деле. Особая роль в задачах исследования действия ударных волн, вызванных технологическими взрывами или горными ударами, принадлежит лучевому методу. С его помощью исследовано напряженное состояние горных выработок при воздействии на них взрывных волн. Предложен динамический критерий прочности для определения устойчивости горных выработок. На конкретном примере показана эффективность разработанной методики.
<i>New Age in Norway</i>, edited by Ingvild Sælid Gilhus, Siv Ellen Kraft and James R. Lewis. 2017
Authors: Swartz Karen 
Published: February 2020

New Age in Norway, edited by Ingvild Sælid Gilhus, Siv Ellen Kraft and
James R. Lewis. 2017. Equinox Publishing. Hb. £75.00/$100.00, ISBN-13:
9781781794166; Pb. £30.00 / $40.00, ISBN-13: 9781781794173; eBook
£30.00 / $40.00, ISBN-13: 9781781795101.
Postoperative Radiotherapy in Pathological T2–3N0M0 Thoracic Esophageal Squamous Cell Carcinoma: Interim Report of a Prospective, Phase III, Randomized Controlled Study
Authors: Deng Wei , Yang Jinsong , Ni Wenjie , Li Chen , Chang Xiao , Han Weiming , Zhou Zongmei , Chen Dongfu , Feng Qinfu , Liang Jun , Lv Jima , Wang Xiaozhen , Wang Xin , Deng Lei , Wang Wenqing , Bi Nan , Zhang Tao , Li Yexiong , Gao Shugeng , Xue Qi , Mao Yousheng , Sun Kelin , Liu Xiangyang , Fang Dekang , Wang Dali , Li Jian , Zhao Jun , Shao Kang , Li Zhishan , Chen Xinjie , Han Lei , Wang Lifang , He Jie , Xiao Zefen 
Published: February 2020

Abstract

Background
The role of postoperative radiotherapy in pathological T2–3N0M0 esophageal squamous cell carcinoma is unknown. We aimed to evaluate the efficacy and safety of postoperative radiotherapy in patients with pathological T2–3N0M0 thoracic esophageal squamous cell carcinoma.

Materials and Methods
Patients aged 18–72 years with pathological stage T2–3N0M0 esophageal squamous cell carcinoma after radical surgery and without neoadjuvant therapy were eligible. Patients were randomly assigned to surgery alone or to receive postoperative radiotherapy of 50.4 Gy in supraclavicular field and 56 Gy in mediastinal field in 28 fractions over 6 weeks. The primary endpoint was disease-free survival. The secondary endpoints were local-regional recurrence rate, overall survival, and radiation-related toxicities.

Results
From October 2012 to February 2018, 167 patients were enrolled in this study. We analyzed 157 patients whose follow-up time was more than 1 year or who had died. The median follow-up time was 45.6 months. The 3-year disease-free survival rates were 75.1% (95% confidence interval [CI] 65.9–85.5) in the postoperative radiotherapy group and 58.7% (95% CI 48.2–71.5) in the surgery group (hazard ratio 0.53, 95% CI 0.30–0.94, p = .030). Local-regional recurrence rate decreased significantly in the radiotherapy group (10.0% vs. 32.5% in the surgery group, p = .001). The overall survival and distant metastasis rates were not significantly different between two groups. Grade 3 toxicity rate related to radiotherapy was 12.5%.

Conclusion
Postoperative radiotherapy significantly increased disease-free survival and decreased local regional recurrence rate in patients with pathological T2–3N0M0 thoracic esophageal squamous cell carcinoma with acceptable toxicities in this interim analysis. Further enrollment and follow-up are warranted to validate these findings in this ongoing trial.
Karst hydrogeology of Lamprechtsofen (Leoganger Steinberge, Salzburg)
Authors: Gröbner Katharina , Gadermayr Wolfgang , Höfer-Öllinger Giorgio , Huemer Harald , Spötl Christoph 
Published: February 2020

Abstract
The Leoganger Steinberge are a heavily karstified massif largely composed of Dachstein dolomite and limestone hosting the deepest through-trip cave in the world, Lamprechtsofen, whose frontal parts are developed as a show cave. Many parts of this 60 km-long and 1724 m-deep system are hydrologically active. 1.5 km behind the lower cave entrance Grüntopf stream and Kneippklamm stream merge to form the main cave stream. Another underground stream, Stainerhallen stream, flows through the eponymous hall of the show cave. Since 2007 water temperature, electrical conductivity and water level have been monitored in the Grüntopf and Kneippklamm stream. Water temperature and water level in the Stainerhallen and main cave stream have been measured since 2016.
The long-term dataset (2013–2017) shows that the water temperature of the cave streams (Grüntopf stream: 3.7–5.2°C; Kneippklamm stream: 5.1–5.9°C) is largely invariant, but the electrical conductivity varies strongly (Grüntopf stream: 107–210 µS/cm; Kneippklamm stream: 131–248 µS/cm) in response to snowmelt and precipitation events. The event water of the Kneippklamm stream is characterized by a low electrical conductivity and is then followed by slightly warmer and higher mineralized water derived from the phreatic zone. This dual flow pattern also explains the asymmetrical changes of the water level during snowmelt: the fast event water flows directly through vadose pathways to the measurement site, whereas the hydraulic (phreatic) response is delayed. The Grüntopf stream reacts to precipitation and snowmelt events by changes in the karst-water table, which can be explained by a piston flow-model. The Kneippklamm stream reveals evidence of a lifter system.
The altitude of the catchments was calculated using δ18O values of water samples from the underground streams and from surface precipitation. The Grüntopf stream shows the highest mean catchment (2280 m a.s.l.), which is in agreement with its daily fluctuations of the water level until August caused by long-lasting snowmelt. The Stainerhallen stream has the lowest catchment (average 1400 m a.s.l.). The catchments of the other two streams are at intermediate elevations (1770–1920 m a.s.l.). The integration of the catchment analyses and observations from tracer tests conducted in the 1970s showed that the latter reflected only one aspect of the karst water regime in this massif. During times of high recharge the water level rises, new flow paths are activated and the karst watershed shifts.