bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinación de los parámetros de productividad de cepas de Pleurotus ostreatus y P. opuntiae cultivadas en paja de trigo y pencas de maguey combinadas con sustratos agrícolas
Authors: Portilla Segura Alejandro , Romero-Arenas Omar , Valencia de Ita Maria De los Ángeles , Hernández Espinosa Miguel Ángel , Lanteta Cortés Gerardo , Rivera-Tapia José Antonio 
Published: May 2020

Antecedentes: La seta silvestre de maguey (Pleurotus opuntiae) es un alimento importante de las zonas semi-áridas del centro de México, apreciado por campesinos e indígenas desde tiempos antiguos, de sabor deseable y aprovechado en épocas de lluvias; sin embargo, hay pocos estudios acerca de su cultivo.
Objetivos: Comparar la producción y calidad nutritiva de basidiomas de P. opuntiae y P. ostreatus cultivados en paja de trigo, así como evaluar la combinación de diferentes residuos agrícolas combinados con penca de maguey para el cultivo de P. opuntiae, en condiciones controladas.
Métodos: Pleurotus opuntiae y P. ostreatus se cultivaron en pencas de maguey y residuos agrícolas pasteurizados a 80 °C/2 h. Se cuantificó la producción total, eficiencia biológica y tasa de producción. Se realizó un estudio químico proximal de los basidiomas obtenidos en los diferentes sustratos. El diseño estadístico fue por bloques al azar, además se realizó un análisis de componentes principales para determinar la correlación entre los rendimientos.
Resultados y conclusiones: Los mejores parámetros productivos se obtuvieron en paja de trigo con la cepa de P. ostreatus, pero P. opuntiae presentó un mayor contenido de proteína cruda y cenizas en la combinación de dos residuos agrícolas con penca de maguey.
Lupus Eritematoso Sistêmico: Novos Paradigmas e Manejo no Atendimento Emergencial – Revisão de Literatura
Authors: Mira Rita , Guanais Soriano Luan , Bittencourt Cunha Catharine , Campos Nascimento Ramon 
Published: May 2020

O lupus eritematoso sistêmico é uma doença autoimune heterogênea, resultante de desregulação complexa do sistema imunológico inato e adaptativo, afetando potencialmente qualquer órgão e / ou tecido. O lupus eritematoso sistêmico é uma doença imunemediada cuja patogênese originária resulta em exposição a autoantígeno, dando origem a numerosos anticorpos auto-reativos de especificidades antigênicas variadas que, juntamente com uma infinidade de citocinas, são consideradas efetoras da atividade da doença. Os regimes de tratamento existentes estão associados a vários efeitos colaterais debilitantes, com pacientes mais jovens em risco aumentado devido à duração do tratamento. Este trabalho teve como objetivo revisar e resumir sistematicamente a literatura disponível sobre a temática do lupus eritematoso sistêmico na população pediatrica através da revisão sistemática por meio de artigos disponibilizados atraves do PubMed e contextualizar a temática por meio de um relato de caso clínico.

Systemic lupus erythematosus is a heterogeneous autoimmune disease, resulting from complex dysregulation of the innate and adaptive immune systems, potentially affecting any organ and/or tissue.Systemic lupus erythematosus is an immunemediated disease whose originating pathogenesis results in autoantigen exposure giving rise to numerous autoreactive antibodies of varying antigenic specificities that along with a myriad of cytokines are thought to be effectors of disease activity.Existing treatment regimens are associated with numerous debilitating side effects, with younger patients at increased risk due to the duration of their disease. This study aimed reviewing and summarizing the available literature of juvenile-onset systemic lupus erythematosus by using articles on PubMed and a case report was related to elucidate the disease.
EFEK KEBISINGAN PADA IBU RUMAH TANGGA SEKITAR BANDARA ADI SUCIPTO YOGYAKARTA
Authors: Nugraha Isnawan Prahardika , Sukismanto Sukismanto , Budiyono Hendarto 
Published: May 2020

Background: The increase of aircraft activities that causes the increase of noise intensity which were suffered by residents around Adi Sucipto airport, especially housewives. Objective: Aimed of the research to know the effect of noise on housewives living near Adi Sucipto airport Yogyakarta, in Jagalan Hamlet, Tegaltirto village, Berbah Sleman district. Method: This is a quantitative descriptive research with a cross sectional approach. This research involved by 32 housewives who live in Jagalan Hamlet, Tegaltirto village, Berbah Sleman district. Results: The results of noise measurement when a plane passing by, show as followed: The result of Lsm (night and day) measurement at point 1 showed 50.02 dB, at point 2 showed 50.05 dB. Noise intensity of a passing airplane during 6 seconds showed between 94 dB to 100 dB. Respon of housewives showed that 32 respondents (100%) disturbed when they were communicating, 26 respondents (81.3%) suffered of stress, 6 respondents (18.8%) did not stressed. Conclusion: Thirty (93.8%) respondents experienced sleep problem, 2 respondents (6.3%) did not. The noise level caused by passing airplanes in Jagalan hamlet during 6 seconds reaches 94 dB up to 100 dB, the results of Lsm measurement at point 1 50.02 dB and point 2 showed 50.05 dB. Communication disturbance were suffered by 32 respondents, stress were suffered by 26 respondents and sleeping problem were suffered by 30 respondents.
Menentukan Batas Kestabilan Steady State Sistem Jawa Bali 500 kV menggunakan Pendekatan Model Single Machine to Infinite Bus
Authors: Rusilawati  
Published: May 2020

The indicator of the power system operation stability can be seen from the power balance between the load demand and the generator output power. The Single Machine to Infinite Bus (SMIB) system that can actually represent the operation of a single machine system in a multimachine system can be used to analyze each generator unit stability. This paper present a fairly simple method to determine the generator steady state stability limit on the Jawa Bali 500 kV system using an SMIB system approach consider the load configuration changes in the system. The Radial Basis Function Neural Network (RBFNN) is applied to simplify the determination of the generator steady state stability limit that changes every time a load configuration changes. The simulation results carried out on the Java Bali system 500 kV 29 bus 10 generators can be seen that the steady state stability limit of each generator unit tends to decrease with the increasing of loading value and the further of load distance from the generator.
Keseimbangan daya antara kebutuhan beban dengan pembangkitan generator merupakan salah satu ukuran kestabilan operasi sistem tenaga listrik., Untuk menganalisis kestabilan setiap unit generator dalam sistem multimachine harus dilakukan pada sistem Single Machine to Infinite Bus (SMIB) yang secara aktual dapat mewakili keadaan sistem single machine tersebut dalam sebuah sistem multimachine. Dalam paper ini digunakan suatu metode sederhana untuk menentukan batas kestabilan steady state setiap unit generator pada sistem multimachine Jawa Bali 500 kV menggunakan pendekatan model sistem SMIB dengan memperhatikan perubahan konfigurasi peletakan beban dalam sistem. Untuk memudahkan penentuan batas kestabilan steady state generator yang selalu berubah setiap saat terjadi perubahan peletakan beban, diaplikasikan salah satu model jaring syaraf tiruan yaitu Radial Basis Function Neural Network (RBFNN). Dari hasil simulasi yang dilakukan pada sistem Jawa Bali 500 kV 29 bus 10 generator dapat diketahui bahwa batas kestabilan steady state setiap unit generator cenderung menurun dengan semakin meningkatnya nilai pembebanan dan semakin jauhnya jarak beban dari pembangkit.
Study Abroad Reentry: Behavior, Affect, and Cultural Distance
Authors: Gray Kelsey M. , Savicki Victor 
Published: May 2020

Reentry has become a more focused aspect of study abroad in recent years as the field has moved away from a laissez-faire approach and toward an emphasis on intervention and support of study abroad students in their efforts to make sense of their experiences (Vande Berg, Paige & Lou, 2012). Although not a new concept (Brathurst & La Brack, 2012), reentry in its more recent incarnation can be seen as an opportunity for students to ratify and reconstrue their encounters with a foreign culture in a way that enhances a sense of self in an intercultural world (Selby, 2008). Despite its history and current popularity, many concepts and ideas about reentry rely on anecdotal, non-research based theorizing. The current study attempts to quantify two important aspects of reentry (behavioral readaptation and emotional response) in the context of measured factors that might impact the intensity of reentry challenges.
Instructor Influence on Student Intercultural Gains and Learning during Instructor-Led, Short-Term Study Abroad
Authors: Anderson Christine L. , Lorenz Karl , White Michael 
Published: May 2020

Short-term study abroad, often in the instructor-led model, is growing with 60% of students enrolling in programs of this length in 2012-13 (IIE, 2014). Higher education institutions’ mission statements often state that creating individuals who have an “international and global understanding” is a goal (Meacham & Gaff. 2006, p. 9). Study abroad is viewed as a premier vehicle to guide students to achieve this expanded worldview. Current education abroad research is not clear on whether intercultural sensitivity can be increased through a short-term, instructor-led program (instructor-led). Previous studies often use metrics focused solely on duration. This comparative focus has led to very little research on interventions that may enhance intercultural learning on instructor-led programs. This study examines 105 students on eight instructor-led programs and aims to demonstrate if intercultural learning can occur on an instructor-led program and what influence the instructor may have on this learning.
TRAJETÓRIA CRONOLÓGICA DO PROFISSIONAL DE EDUCAÇÃO FÍSICA
Authors: Hartmann Cassio , César Dias Lopes Gabriel , Da Silva Ferreira Vieira Fábio , V Samuel Bensson 
Published: May 2020

O presente estudo teve como objetivo, apresentar a trajetória dos profissionais de Educação Física, desde a década de 1977 até o período de 2020, aonde a categoria conquista permanentemente através da CBO Classificação Brasileira de Ocupações, a inserção o rofissional de Educação Física na Saúde, que ocorreu em 17 de fevereiro de 2020 com o código 2241-40. A referida pesquisa aracteriza-se como documental parecida com a pesquisa bibliográfica. Diante das considerações finais dessa pesquisa, o profissional e Educação Física, deverá e conseguirá desenvolver ações que propiciem a melhoria da qualidade de vida da população, fim de reduzir os agravos e danos decorrentes das doenças não-transmissíveis, que favoreçam a redução do consumo e medicamentos e principalmente trabalhar em equipe multidisciplinar do SUS Sistema Único de Saúde.
Hydroxychloroquine in Patients with Rheumatic Disease Complicated by COVID-19: Clarifying Target Exposures and the Need for Clinical Trials
Authors: Balevic Stephen J. , Hornik Christoph P. , Green Thomas P. , Clowse Megan E.B. , Gonzalez Daniel , Maharaj Anil R. , Schanberg Laura E. , Eudy Amanda M. , Swamy Geeta K. , Hughes Brenna L. , Cohen-Wolkowiez Michael 
Published: May 2020

Objective.To characterize hydroxychloroquine (HCQ) exposure in patients with rheumatic disease receiving longterm HCQ compared to target concentrations with reported antiviral activity against the coronavirus disease 2019 caused by SARS-CoV-2 (COVID-19).Method.We evaluated total HCQ concentrations in serum and plasma from published literature values, frozen serum samples from a pediatric systemic lupus erythematosus trial, and simulated concentrations using a published pharmacokinetic model during pregnancy. For each source, we compared observed or predicted HCQ concentrations to target concentrations with reported antiviral activity against SARS-CoV-2.Results.The average total serum/plasma HCQ concentrations were below the lowest SARS-CoV-2 target of 0.48 mg/l in all studies. Assuming the highest antiviral target exposure (total plasma concentration of 4.1 mg/l), all studies had about one-tenth the necessary concentration for in vitro viral inhibition. Pharmacokinetic model simulations confirmed that pregnant adults receiving common dosing for rheumatic diseases did not achieve target exposures; however, the models predict that a dosage of 600 mg once a day during pregnancy would obtain the lowest median target exposure for most patients after the first dose.Conclusion.We found that the average patient receiving treatment with HCQ for rheumatic diseases, including children and non-pregnant/pregnant adults, are unlikely to achieve total serum or plasma concentrations shown to inhibit SARS-CoV-2 in vitro. Nevertheless, patients receiving HCQ long term may have tissue concentrations far exceeding that of serum/plasma. Because the therapeutic window for HCQ in the setting of SARS-CoV-2 is unknown, well-designed clinical trials that include patients with rheumatic disease are urgently needed to characterize the efficacy, safety, and target exposures for HCQ.
Intravenous Infusion of Cortisol, Adrenaline, or Noradrenaline Alters Porcine Immune Cell Numbers and Promotes Innate over Adaptive Immune Functionality
Authors: Reiske Lena , Schmucker Sonja , Pfaffinger Birgit , Weiler Ulrike , Steuber Julia , Stefanski Volker 
Published: May 2020

Abstract
Despite the importance of pigs (Sus scrofa domestica) in livestock production and their increasing role as a model organism for human physiology, knowledge about the porcine immune system under the influence of stress hormones is fragmentary. Exceptionally little is known about the effects of catecholamines. Therefore, the aim of this study was to examine the in vivo effects of adrenaline, noradrenaline, and cortisol on number and functionality of porcine blood immune cells. Castrated male pigs (n = 34) were treated with physiological doses of either adrenaline, noradrenaline, or cortisol via i.v. infusion for 48 h. Blood samples were collected before treatment (−24 h, −22 h, 0 h), during treatment (+2 h, +24 h, +48 h), and at 72 h postinfusion. Immune cell numbers and phagocytic activity were evaluated by flow cytometry and lymphocyte proliferation by 3H-thymidine incorporation. Total IgG and IgM Ab levels were determined via ELISA. Pigs receiving cortisol showed strongly decreased adaptive immune cell numbers and increased neutrophils, accompanied by hampered lymphocyte proliferation but increased monocyte phagocytosis. Catecholamine effects on immune cell numbers were mostly similar to cortisol in direction but smaller in intensity and duration. Lymphocyte proliferation was inhibited after 2 h of noradrenaline infusion, and both catecholamines promoted monocyte and neutrophil phagocytosis. These findings indicate a shift from adaptive to innate immunity in stressful situations. This study is the first (to our knowledge) to systematically investigate specific glucocorticoid and catecholamine actions on the porcine immune system in this level of detail and confirms many similarities to humans, thus strengthening the pig as a human model in psychoneuroimmunology.
Integrating palaeoclimate time series with rich metadata for uncertainty modelling: strategy and documentation of the PalMod 130k marine palaeoclimate data synthesis
Authors: Jonkers Lukas , Cartapanis Olivier , Langner Michael , McKay Nick , Mulitza Stefan , Strack Anne , Kucera Michal 
Published: May 2020

Abstract. Palaeoclimate data hold the unique promise of providing a long-term
perspective on climate change and as such can serve as an important
benchmark for climate models. However, palaeoclimate data have generally
been archived with insufficient standardisation and metadata to allow for
transparent and consistent uncertainty assessment in an automated way.
Thanks to improved computation capacity, transient palaeoclimate simulations
are now possible, calling for data products containing multi-parameter time
series rather than information on a single parameter for a single time
slice. Efforts are underway to simulate a complete glacial–interglacial
cycle using general circulation models (https://www.palmod.de/, last access: 6 May 2020), and to confront these
simulations with palaeoclimate data, we have compiled a multi-parameter
marine palaeoclimate data synthesis that contains time series spanning 0 to
130 000 years ago. We present the first version of the data product that
focuses exclusively on time series for which a robust chronology based on
benthic foraminifera δ18O and radiocarbon dating is available.
The product contains 896 time series of eight palaeoclimate parameters from
143 individual sites, each associated with rich metadata, age–depth model
ensembles, and information to refine and update the chronologies. This
version contains 205 time series of benthic foraminifera δ18O;
169 of benthic foraminifera δ13C; 131 of seawater temperature;
174 and 119 of planktonic foraminifera δ18O and δ13C; and 44, 38 and 16 of carbonate, organic carbon and biogenic silica
content, respectively. The data product is available in three formats (R,
LiPD and netCDF) facilitating use across different software and operating
systems and can be downloaded at https://doi.org/10.1594/PANGAEA.908831 (Jonkers et al., 2019). This
data descriptor presents our data synthesis strategy and describes the
contents and format of the data product in detail. It ends with a set of
recommendations for data archiving.
Modeling inorganic carbon dynamics in the Seine River continuum in France
Authors: Marescaux Audrey , Thieu Vincent , Gypens Nathalie , Silvestre Marie , Garnier Josette 
Published: May 2020

Abstract. Inland waters are an active component of the carbon cycle where
transformations and transports are associated with carbon dioxide (CO2) outgassing. This study estimated CO2 emissions from the human-impacted Seine River (France) and provided a detailed budget of aquatic carbon transfers for organic and inorganic forms, including the in-stream metabolism along the whole Seine River network. The existing process-based biogeochemical pyNuts-Riverstrahler model was supplemented with a newly developed inorganic carbon module and simulations were performed for the recent time period 2010–2013. New input constraints for the modeling of riverine inorganic carbon were documented by field measurements and complemented by analysis of existing databases. The resulting dissolved inorganic carbon (DIC) concentrations in the Seine aquifers ranged from 25 to 92 mg C L−1, while in wastewater treatment plant (WWTP) effluents our DIC measurements averaged 70 mg C L−1. Along the main stem of the Seine River, simulations of DIC, total alkalinity, pH and CO2 concentrations were of the same order of
magnitude as the observations, but seasonal variability was not always well
reproduced. Our simulations demonstrated the CO2 supersaturation with respect to atmospheric concentrations over the entire Seine River network. The most significant outgassing was in lower-order streams while peaks were simulated downstream of the major WWTP effluent. For the period studied (2010–2013), the annual average of simulated CO2 emissions from the Seine drainage network were estimated at 364±99 Gg C yr−1. Results from metabolism analysis in the Seine hydrographic network
highlighted the importance of benthic activities in headwaters while
planktonic activities occurred mainly downstream in larger rivers. The net
ecosystem productivity remained negative throughout the 4 simulated years
and over the entire drainage network, highlighting the heterotrophy of the
basin. Highlights
CO2 emission from the Seine River was estimated at 364±99 Gg C yr−1 with the Riverstrahler model. CO2 riverine concentrations are modulated by groundwater discharge and instream metabolism. CO2 emissions account for 31 % of inorganic carbon exports, the rest being exported as DIC.
‘A Person’s a Person, No Matter How Small’: enige literaire intermezzi
Authors: Gaakeer A.M.P. (Jeanne) 
Published: May 2020

‘A Person’s a Person, No Matter How Small’: enige literaire intermezzi
De ontwikkeling van de rechten van het kind valt behalve in het recht ook in de (kinder)literatuur te traceren. Literaire werken met juridische thema’s zijn daarom een spiegel voor zowel juristen als minderjarigen in de manier waarop zij in het verhaal dat wordt verteld rechten en plichten in het concrete geval aanschouwelijk maken. Een kleine staalkaart van literaire fragmenten toont de positie van het kind in het recht.
De strafwetgever en kinderrechten: nog te veel een opgedrongen ideaal?
Authors: uit Beijerse J. (Jolande) 
Published: May 2020

De strafwetgever en kinderrechten: nog te veel een opgedrongen ideaal?
In het kader van de modernisering van het Wetboek van Strafvordering wordt ook beoogd het hele jeugdstrafprocesrecht te herzien. De vraag is echter of de strafwetgever bij die gelegenheden, conform artikel 4 IVRK, passende wettelijke maatregelen heeft genomen om de in het verdrag opgenomen minimumstandaard aan kinderrechten te verwezenlijken.
De rechtspositie van aangehouden minderjarige verdachten in de eerste fase van het strafrechtelijk onderzoek
Authors: Jeltes M. (Marije) 
Published: May 2020

De rechtspositie van aangehouden minderjarige verdachten in de eerste fase van het strafrechtelijk onderzoek
In deze bijdrage wordt de rechtspositie van aangehouden minderjarige verdachten vanaf het moment van aanhouding tot en met de voorgeleiding onderzocht en naast de lat van Europese en internationale kinderrechten gelegd. Welke rechten en plichten hebben minderjarige verdachten in het Nederlandse rechtssysteem tijdens de eerste fase van het strafrechtelijk onderzoek, welke rol hebben Europese regelgeving en internationale kinderrechten in de totstandkoming van deze rechten en plichten gespeeld en voldoet Nederland aan dit internationale kader van kinderrechten?
Kindvriendelijke rechtspraak – wat valt te verwachten voor het jeugdstrafrecht?
Authors: van Kalveen E.A.A. (Ellen) 
Published: May 2020

Kindvriendelijke rechtspraak – wat valt te verwachten voor het jeugdstrafrecht?
In Nederland is in de laatste jaren de aandacht voor kindvriendelijke rechtspraak vooral gericht op het jeugdbeschermingsrecht en op familiezaken. In deze bijdrage wordt nagaan welke praktische aspecten in het jeugdstrafrecht aandacht behoeven in het licht van kindvriendelijke rechtspraak.
Kinderrechten en de positie van jongvolwassenen
Authors: Schmidt E.P. (Eva) 
Published: May 2020

Kinderrechten en de positie van jongvolwassenen
Internationale kinderrechten genieten enerzijds vrijwel universele erkenning maar worden anderzijds ook stevig bekritiseerd. Vooral kinderrechten binnen het strafrecht worden als controversieel gezien. Tegelijkertijd is op dit gebied sprake van toenemende aandacht voor de ontwikkeling gedurende de adolescentie die door lijkt te lopen na de dominante leeftijdgrens van achttien jaar, alsmede de implicaties daarvan voor de positie van jongvolwassenen in het strafrecht. Deze bijdrage gaat nader in op de toepasselijkheid, en toegevoegde waarde, van het kinderrechtenperspectief voor jongvolwassenen in het strafrecht.
DE RÁDIOS A REDES COMUNITÁRIAS? REFLEXÕES SOBRE OS NOVOS CAMINHOS TECNOPOLÍTICOS DA COMUNICAÇÃO COMUNITÁRIA
Authors: Malerba João Paulo 
Published: May 2020

O artigo analisa as mudanças tecnológicas e políticas que têm afetado as mídias comunitárias no contexto dos desafios da convergência midiática e da hegemonia de um novo modo de ação política que contrasta com o modo como originalmente se conformaram tais atores. Tendo como objeto de estudo as transformações nos modos de ser das rádios comunitárias, são discutidos os descompassos, desafios e adaptações tecnopolíticas do encontro desses antigos atores sociais com a comunicação em rede. O artigo se vale de pesquisas bibliográfica, documental e conceitual; observação-participante; entrevistas semiestruturadas; além de duas pesquisas empíricas interdependentes no intuito de contribuir para o campo da Comunicação Comunitária desde a análise do desenvolvimento político e tecnológico de seu objeto.