bluuebunny/crossref_metadata_2025_split huggingface dataset:
Twee heren (in één transactie) dienen, mag dat nu wel of (soms) toch niet?
Authors: Oostwouder W.J. , Spronk T. 
Published: October 2019

Twee heren (in één transactie) dienen, mag dat nu wel of (soms) toch niet?
De wet bevat geen duidelijke definitie voor het begrip ‘tegenstrijdig belang’. Ook de wetsgeschiedenis biedt onvoldoende aanknopingspunten voor een eenduidige interpretatie van dit begrip en zijn toepassing. De minister verwijst wel naar het in 2007 gewezen Bruil-arrest. Hieruit blijkt dat ook in het sinds 2013 geldende recht moet worden uitgegaan van de in dit arrest aangenomen verschuiving van de abstracte leer naar de materiële leer. Dit neemt niet weg dat er twijfels ontstaan over de ex-antetoepassing van de ex post geformuleerde Bruil-norm, de specifieke invulling van het materiële begrip en de verhouding tussen de tegenstrijdig-belangregeling en de Linders/Hofstee-regels. Deze onduidelijkheid wordt versterkt door de verschillende interpretaties van dit begrip in de governancecodes en recente uitspraken van de Ondernemingskamer en de Governancecommissie Gezondheidszorg. Een verheldering van dit begrip door de wetgever in het kader van de behandeling van het wetsvoorstel Wet bestuur en toezicht rechtspersonen zou derhalve gewenst zijn.
Van WCAM naar WAMCA: class actions in Nederland?
Authors: van der Krans A. 
Published: October 2019

Van WCAM naar WAMCA: class actions in Nederland?
Op 19 maart 2019 is de wet afwikkeling massaschade in collectieve actie (WAMCA) door de Eerste Kamer aangenomen. Inwerkingtreding wordt verwacht voor 1 oktober 2019. Na de inwerkingtreding van de WAMCA zal het collectief vorderen van schadevergoeding mogelijk zijn. De WAMCA is een belangrijke ontwikkeling op het gebied van het collectief schadevergoedingsrecht in Europa, maar is vatbaar voor verbetering, vooral op het terrein van finaliteit, governance-eisen, financiering en hoger beroep.
BCR-ABL1–like B-Acute Lymphoblastic Leukemia/Lymphoma: A Comprehensive Review
Authors: Jain Sarika , Abraham Anu 
Published: October 2019

Context.—
In the 2016 update of the World Health Organization (WHO) classification of hematopoietic neoplasms, BCR-ABL1–like B-acute lymphoblastic leukemia/lymphoma (B-ALL) is added as a new provisional entity that lacks the BCR-ABL1 translocation but shows a pattern of gene expression very similar to that seen in B-ALL with BCR-ABL1.

Objective.—
To review the kinase-activating alterations and the diagnostic approach for BCR-ABL1–like B-ALL.

Data Sources.—
We provide a comprehensive review of BCR-ABL1–like B-ALL based on recent literature and the 2016 update of the World Health Organization classification of hematopoietic neoplasms.

Conclusions.—
Several types of kinase-activating alterations (fusions or mutations) are identified in BCR-ABL1–like B-ALL. The main categories are alterations in the ABL class family of genes, encompassing ABL1, ABL2, PDGFRB, PDGFRA (rare), and colony-stimulating factor 1 receptor (CSF1R) fusions, or the JAK2 class family of genes, encompassing alterations in JAK2, CRLF2, EPOR, and other genes in this pathway. These alterations determine the sensitivity to tyrosine kinase inhibitors. As a wide variety of genomic alterations are included in this category, the diagnosis of BCR-ABL1–like B-ALL is extremely complex. Stepwise algorithms and comprehensive unbiased testing are the 2 ways to approach the diagnosis of BCR-ABL1–like B-ALL.
Morphologic Spectrum of Neuroendocrine Tumors of the Prostate: An Updated Review
Authors: Hu Jing , Han Bo , Huang Jiaoti 
Published: October 2019

Context.—The incidence of neuroendocrine tumors of the prostate increases after hormonal therapy. Neuroendocrine tumors possess a broad spectrum of morphologic features and pose challenges in the pathologic diagnosis and clinical management of patients.Objective.—To present a brief updated summary of neuroendocrine tumors of the prostate with an overview of their histopathologic and immunohistochemical profiles and differential diagnoses.Data Sources.—Literature review, personal experience in the daily practice of pathologic diagnosis, and laboratory research.Conclusions.—Our understanding of neuroendocrine tumors of the prostate classification and diagnosis continues to evolve. These advances benefit the risk stratification and management of prostate cancer.
Índices de qualidade da paisagem no campo petrolífero de Carmópolis, Sergipe
Authors: Sobral Ivana Silva , Silva Gicélia Mendes , Menezes Daniela Monique Guimarães 
Published: October 2019

O campo petrolífero de Carmópolis, um dos maiores produtores de petróleo onshore do país, é importante economicamente para o Estado de Sergipe; contudo causa impactos ambientais significativos. A fim de subsidiar o processo de licenciamento, esta pesquisa objetivou analisar a qualidade da paisagem nos municípios de Carmópolis e Japaratuba, por meio de índices. Constatou-se que: os índices de qualidade da paisagem do município de Carmópolis e Japaratuba são, respectivamente, 0,54 e 0,55, classificado como regular; a pecuária é matriz das paisagens de ambos os municípios; os poços, as estradas e os dutos de gás e petróleo fragmentam as paisagem, comprometendo as resiliências dos ecossistemas naturais. Assim, as hipóteses de que as paisagens dos municípios de Carmópolis e Japaratuba estão sendo degradadas pela atividade petrolífera e de que os impactos ambientais não estão sendo mitigados adequadamente foram confirmadas. Para revertem o processo de degradação, torna-se mister a implantação de ações de manejo prioritárias para cessar, minimizar e compensar os impactos ambientais; assegurar a proteção dos ecossistemas naturais e a qualidade de vida da população. Dentro desse contexto, a fiscalização, a recuperação ambiental, a implantação de corredores ecológicos por meio do reflorestamento com espécies nativas são ferramentas importantes para planejamento ambiental da mineração no Campo Petrolífero de Carmópolis.
Diagnóstico da mudança na configuração espacial de produtividade da fruticultura no Espírito Santo, Brasil, nos anos 2011 e 2016
Authors: Galeano Edileuza Vital , Ventura José Aires , Souza Renzo Caliman , Silva Bruce Francisco Pontes da 
Published: October 2019

No estado do Espírito Santo, recentemente a fruticultura foi afetada negativamente pelas adversidades climáticas e um novo rearranjo produtivo tem sido verificado. Neste contexto, procurou-se explorar a produtividade média da fruticultura entre os anos de 2011 e 2016, identificando padrões de localização espacial. Corroborou-se a hipótese de dependência espacial e em 2011 foi identificado um cluster de alta produtividade (HH), o qual compreende sete municípios no Extremo Norte do estado. O estudo mostrou que houve uma mudança na configuração e localização dos clusters em 2016. Apesar dos avanços obtidos no setor, o estudo evidenciou que a fruticultura capixaba se mostrou pouco preparada para situações de adversidades climáticas. Estes resultados podem auxiliar nas tomadas de decisões técnicas e políticas futuras para o setor.PALAVRAS-CHAVE: Produtividade, fruticultura, cluster, dependência espacial. ABSTRACTIn the state of Espírito Santo, Brazil, recently the fruit crops was negatively affected by the climatic adversities and one new productive rearrangement has been verified. In this context, we tried to explore the average productivity of the fruit crops between the years 2011 and 2016, identifying patterns of spatial location. The hypothesis of spatial dependence was corroborated and in 2011 a high productivity cluster (HH) was identified, which comprises seven municipalities in the extreme North of the state. The study showed that there was a significant change in the configuration and location of the clusters in 2016. Despite the advances obtained in the sector, the study evidenced that the fruticulture in Espírito Santo showed to be poorly prepared for situations of climatic adversity. These results can aid in making technical decisions and future policies for the sector.KEYWORDS: Productivity, fruticulture, cluster, spatial dependence.
Logística e comércio internacional da fruticultura no estado de Minas Gerais - Brasil
Authors: Oliveira Igor Martins , Pereira Luiz Andrei Gonçalves 
Published: October 2019

Na era globalização, a economia mundial tem vivenciado um processo de reestruturação produtiva, intensificando os fluxos nos territórios inerentes às interações espaciais de recursos, de bens e de serviços que circulam entre os mercados nacionais e internacionais. O objetivo deste trabalho é analisar as dinâmicas socioespaciais dos fluxos de comércio internacional do estado de Minas Gerais por meio da logística das redes de importações e de exportações de frutas, no período de 2000 a 2017. Como resultado, identificou-se que, no mercado externo de frutas, Minas Gerais se relaciona comercialmente com 88 países, sendo 52 nas redes de exportação e 36 na rede de importação. Na operacionalização dos fluxos no comércio global, a logística de transportes foi realizada através dos modais rodoviário, marítimo e aéreo, configurando-se como um elemento geográfico, visto que as transações comerciais demandam o gerenciamento da fluidez, do planejamento e da organização dos diferentes territórios.PALAVRAS-CHAVE: Logística, Comércio Internacional, Fruticultura. ABSTRACTIn the era of globalization, the world economy has undergone a process of productive restructuring, intensifying flows in the territories inherent to the spatial interactions of resources, goods and services that circulate between national and international markets. The objective of this work is to analyze the sociospatial dynamics of the international trade flows of the state of Minas Gerais through the logistics of import and export fruit networks, from 2000 to 2017. As a result, it was identified that in the market Minas Gerais has a commercial relationship with 88 countries, 52 in export networks and 36 in the import network. In the operationalization of flows in global trade, transport logistics was carried out through the road, sea and air modalities, being configured as a geographic element, since commercial transactions demand the management of the fluidity, planning and organization of the different territories.KEYWORDS: Logistic, International Trade, Fruticulture.
A relação entre Estado e territórios estigmatizados no Rio de Janeiro
Authors: De Abreu André Almeida 
Published: October 2019

O presente artigo tem o intuito discutir a relação estabelecida entre o Estado e as favelas do Rio de Janeiro ao longo do tempo e até os dias atuais. Tomando como referência a territorialização de políticas públicas e a ação de instituições estatais e da sociedade civil, busca-se compreender de que forma a estigmatização do favelado e de seu território influencia as relações de poder construídas no contato entre agentes públicos e moradores de favela. O artigo consiste, metodologicamente, em uma pesquisa bibliográfica e documental, com base principalmente na literatura sobre o tema. Os resultados indicam que a estigmatização das favelas tem contaminado diversas políticas públicas formuladas para esses territórios, e que a falta de diálogo entre diferentes órgãos públicos envolvidos em tais políticas gera o que chamamos de atrofia burocrática, perdendo-se potencial de atuação da esfera pública.PALAVRAS-CHAVE: Políticas Públicas, Favela, Territorialização. ABSTRACTThis article aims to discuss the relationship established between the State and the favelas of Rio de Janeiro over time and up to the present day. Taking as a reference the territorialization of public policies and the action of state institutions and civil society, it is sought to understand how the stigmatization of the favela and its territory influences the relations of power built in the contact between public agents and residents of favela. The article consists, methodologically, of a bibliographical and documentary research, based mainly on the literature on the subject. The results indicate that the stigmatization of favelas has contaminated several public policies formulated for these territories, and that the lack of dialogue between different public agencies involved in such policies generates what we call bureaucratic atrophy, losing the potential of the public sphere.KEYWORDS: Public Policies, Favela, Territorialization.
Women’s Musical Agency and Experiences in Vernon Lee’s Music and its Lovers
Authors: Franseen Kristin 
Published: October 2019

Among the case studies included in Vernon Lee’s last book, Music and its Lovers (1933) one finds an intriguing alliance between gender and the experience of listening to instrumental music. A respondent identified only as “The Suffragette” directly ties her feelings about music to her activism, noting that “I recognize in music some definite emotions pertaining to a crowd…the growl I have heard in crowds at suffrage meetings” and later writing about Brahms that “I think I can distinguish in music secondary sex attributes.” Lee notes that the Suffragette, while untrained in music, appears perceptive in linking instrumental music to her personal experiences.
While prior research on Music and its Lovers (Towheed 2010 and 2013; Mahoney 2015) has focused primarily on Lee’s sources and questionable scientific practices, this article examines the repertoire and accounts of listening submitted by some of Lee’s female participants. Although Lee’s respondents and ultimate theories of musical emotion cut across gender, her lengthy excerpts from her own experiments center women’s experiences as listeners with valuable observations into the musical experience. In collecting case studies from within her own social circle of women artists and intellectuals, Lee preserved an important archive of early twentieth-century women’s thoughts about specific types of music, especially when it comes to composers traditionally associated with masculinity (Brahms and Beethoven) and sexuality (Tchaikovsky and Wagner).
« Rip It Up and Start Again » : reconfigurations de l’audible sous le régime esthétique des arts*
Authors: Frappier Daniel 
Published: October 2019

Ce texte propose de repenser l’intégration du bruit en musique, un phénomène trop souvent confiné aux seuls xxe et xxie siècles, à partir des réflexions de Jacques Rancière sur ce qu’il nomme le « régime esthétique » : révolution dans les manières de penser et de sentir qui, propulsée par le romantisme et toujours en cours, dérègle les conceptions de la société et de l’art héritées de la Grèce antique. En matière de création et d’appréciation des oeuvres, l’ère nouvelle se caractérise par un recul de l’idéal classique de l’éloquence, de la forme animée par un contenu à transmettre, au profit du modèle de la « parole muette », de la signification qui échappe au contrôle du maître. Cette dernière, explique Rancière, peut être pensée de deux façons. Comme immanence du logos dans le pathos, elle est le pouvoir expressif des choses muettes elles-mêmes : la signification ou la poésie secrètes des détails sans importance, offertes à qui sait regarder. Comme immanence du pathos dans le logos, à l’inverse, elle est la part de non-sens qui se cache derrière le discours le plus rigoureusement articulé comme dans toute autre construction rationnelle : puissance obscure à laquelle les artistes métaphysiciens ou psychanalystes tentent, tant bien que mal, de donner corps. Si la parole muette et ses deux formes contradictoires peuvent déloger l’éloquence comme principe de la création, c’est parce que le régime esthétique est tout déployé autour de l’idée de l’égalité des contraires : du noble et du vulgaire, de l’actif et du passif, du conscient et de l’inconscient etc. En prenant appui sur ces réflexions, donc, ce texte propose de retracer quelques-uns des discours et des pratiques qui, du romantisme à aujourd’hui, brouillent les frontières entre le sens et le non-sens, l’art et le non-art, la musique et le bruit.
Professional Activities (1930–1981) of Latvian-Born Lithuanian Architect and Engineer Karolis Reisonas (1894–1981) in Kaunas, Panevėžys and Adelaide Cities
Authors: Saladžinskas Sigitas Vladas , Vaisvalavičienė Kristina 
Published: October 2019

The article introduces the professional activities of Latvian-born Lithuanian architect and engineer Karolis Reisonas (in Latvian: Kārlis Reisons; 1894–1981) in the second half of his life – from 1930 in Kaunas, Panevėžys and Adelaide cities – and his role in the history of Lithuanian architecture. K. Reisonas was one of the most prominent creators of modern 20th-century interwar Lithuanian architecture and together with other famous Lithuanian architects formed a special style of Kaunas modern architecture in interwar period. K. Reisonas is the author or co-author of representative buildings in Šiauliai, Kaunas and other Lithuanian cities, as well as in Riga and Adelaide cities. Architect and engineer K. Reisonas worked as Šiauliai City Engineer and Head of Municipal Construction Department (1922–1930), Director of Šiauliai Vocational School (1926), Consultant of Lithuanian Chamber of Agriculture (1927–1928), Head of Construction Department of Kaunas Municipality (1930– 1938), Panevėžys City Engineer (1940) and Burgomaster (1941–1944). From 1949, the Reisonas family lived in Adelaide city, Australia. To his projects three monuments of independence were built in Lithuania – Monument of Independence in Šiauliai city, Podium of the Freedom Monument of Kaunas city and Roman Catholic Christ’s Resurrection Church in Kaunas city. Fourteen of buildings in Lithuania (in Kaunas and Šiauliai cities) designed by him are included in the list of cultural values of Lithuania. Early K. Reisonas’ projects are characterized by historism, elements of eclecticism and «brick style», later projects are characterized by austere rationalism, functionalism, adaptation to urban construction and cultural and historical context.
Effectiveness of Probiotics, Metformin and Their Combination Therapy in Ameliorating Dyslipidemia Associated With PCOS
Authors: Zafar Urooj , Hassan Jahan Ara , Ismail Kauser , Agha Shanza , Memon Zahida , Bhatty Shaheen 
Published: October 2019

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous metabolic disorder affecting women of the child-bearing age. Alteration in lipid profile is one of the troublesome features faced by PCOS patients that need to be treated.
Aim: The purpose of this study was to compare the effects of Probiotics, Metformin and their Combination therapy on lipid profile in women suffering from PCOS.
Study Design: Single-Centered Randomized Controlled Trial.
Setting: Gynecological clinic of Karachi at Tertiary care Hospital from December 2018 to May 2019.
Patients and Methods: Total 78 PCOS patients of age between 18 to 40 years were involved in this trial rendering to Rotterdam criteria. After taking written and informed consent they were randomly allocated to three groups and were received: Metformin 500 mg B.D (n = 26), Probiotic Capsule 180 mg B.D (n = 26) and Combination of Metformin 500 mg B.D / Probiotic Capsule 180 mg B.D for 12-weeks. Lipid profile was measured at baseline and after 12-weeks of intervention along with the body weight. In the end, pre versus post therapy and comparison of different group’s results were analyzed.
Results: Metformin and Met/Pro Combination groups resulted in a significant reduction in Total Cholesterol (TC) as compared to Probiotic group. Fall in Low-Density Lipoprotein Cholesterol (LDL-C) levels were noteworthy after Probiotics and Met/Pro treatment. Serum TG concentrations were significantly reduced in all the groups. High-Density Lipoprotein Cholesterol (HDL-C) levels were slightly elevated after Probiotics treatment, which was not statistically significant but Metformin and Met/Pro group increases it to the significant value. No substantial change was found in the Very Low-Density Lipoprotein Cholesterol VLDL-C levels in any of the three groups.
Conclusion: Overall, Probiotics treatment in PCOS women for 12 weeks exhibited noteworthy changes in TG, and LDL-C levels. Metformin markedly improve Cholesterol, TG and HDL-C. However, Met/Pro improved all the lipid changes to the significant value except for VLDL-C.
Using statistics to design and estimate vital rates in matrix population models for a perennial herb
Authors: Ramula Satu , Kerr Natalie Z. , Crone Elizabeth E. 
Published: October 2019

AbstractMatrix population models are widely used to assess population status and to inform management decisions. Despite existing theories for building such models, model construction is often partially based on expert opinion. So far, model structure has received relatively little attention, although it may affect estimates of population dynamics. Here, we assessed the consequences of two published matrix structures (a 4 × 4 matrix based on expert opinion and a 10 × 10 matrix based on statistical modeling) for estimates of vital rates and stochastic population dynamics of the long‐lived herb Astragalus scaphoides. We explored the ways in which choice of model structure alters the accuracy (i.e., mean) and precision (i.e., variance) of predicted population dynamics. We found that model structure had a negligible effect on the accuracy and precision of vital rates and stochastic stage distribution. However, the 10 × 10 matrix produced lower estimates of stochastic population growth rates than the 4 × 4 matrix, and more accurately predicted the observed trends in population abundance for three out of four study populations. Moreover, estimates of realized variation in population growth rate due to fluctuations in population stage structure over time were occasionally sensitive to matrix structure, suggesting differential roles of transient dynamics. Our study indicates that statistical modeling for choosing categories in matrix models might be preferable over expert opinion to accurately predict population trends and can provide a more objective way for model construction when the biological knowledge of the species is limited.
Borreliella
Authors: Barbour Alan G. , Qiu Weigang 
Published: October 2019

AbstractBor.rel.i.el'la. N.L. fem. dim. n.Borreliellanamed after Amédée Borrel (1867–1936).Spirochaetes / Spirochaetes / Spirochaetales / Borreliaceae / BorreliellaCells are helical, 0.2–0.3 µm in diameter, 15–30 µm in length, and do not have hooked ends. Coils are regular or irregular in spacing and amplitude. Motile. Inner and outer membranes with overlapping periplasmic flagella; 7–11 subterminal insertion points in most species. Aniline‐stain‐positive. Microaerophilic. Ferments glucose. Most species are cultivable in complex, serum‐containing media that includeN‐acetylglucosamine. Optimum growth is between 33 and 38°C. Cells are polyploid, with each genome comprising a linear chromosome and one or more linear and circular plasmids. All known species are host‐associated organisms that are transmitted among mammalian, avian, and reptile reservoirs by a tick of the prostriate genusIxodes. In unfed ticks, the organisms are located in the midgut and only travel to the salivary glands once the next blood meal commences. Transovarial transmission in tick vector does not occur. Members of this genus include all known agents of Lyme disease (Lyme borreliosis) as well as several species not associated with human disease.DNA G + C content (mol%): 28–29.Type species:Borreliella burgdorferi(Adeolu and Gupta 2014, VL163) (basonym:Borrelia burgdorferiJohnson et al. 1984bVP).