bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hydrosonographic Assessment of the Effect of Two Different Suture
Materials on Healing of the Uterine Scar after Cesarean Delivery: A Prospective
Randomized Controlled Trial
Authors: Sevket Osman , Takmaz Taha , Ozcan Pinar , Halici Belfin Nur Arici , Islek Sevde Havva 
Published: June 2020

Abstract
Purpose This study aimed to compare the effects of two different suture
materials, monofilament synthetic absorbable sutures versus multifilament
synthetic absorbable sutures, on healing the uterine scar after a cesarean
delivery.
Methods A total of 95 women between the ages of 18 and 40 who had
undergone a primary cesarean section (CS) after the 38th week of
gestation. In Group I (n=48), continuous double-layer unlocked closure
of the low transverse uterine incision was performed using monofilament
synthetic absorbable sutures. In Group II (n=47), continuous
double-layer unlocked closure of the low transverse uterine incision was
performed using multifilament synthetic absorbable sutures. Six months after the
operation, the integrity of the cesarean scar at the uterine incision site was
assessed using hydrosonography. The healing ratio and the thickness of the
residual myometrium covering the defect were calculated as markers of uterine
scar healing.
Results No statistically significant differences were observed between
the groups with regard to the preoperative hemoglobin concentrations, the change
in the hemoglobin concentrations, operating time, and the number of
intraoperative additional hemostatic uterine sutures. Mean thickness of the
residual myometrium covering the defect was thicker in the monofilament suture
group in comparison to the multifilament suture group (7.76±2.11 vs.
5.96±1.69, respectively; p<0.01). The mean healing ratio was
significantly higher in the monofilament suture group in comparison to the
multifilament suture group (0.76±0.13 vs. 0.60±0.12,
respectively; p<0.01)
Conclusion Continuous double-layer unlocked closure of the uterine
incision at cesarean delivery using monofilament synthetic absorbable sutures
decreases the risk of CS scar defect.
Epidemiology of Injuries in Elite Female Futsal Players: A
Prospective Cohort Study
Authors: Lago-Fuentes Carlos , Jiménez-Loaisa Alejandro , Padrón-Cabo Alexis , Calvo Marcos Mecías , García-Pinillos Felipe , Rey Ezequiel 
Published: June 2020

AbstractInjuries are one of the worst case scenarios for an athlete and a team. The aim
of this study was to analyze the injury incidence, characteristics and burden
among a cohort of elite female futsal players. A prospective cohort study was
designed over a season. Eighty-nine players from seven elite female futsal teams
were monitored during the whole season. Eight different variables were recorded
when an injury happened, as well as exposure time. A total of 90 injuries were
recorded so that 54 out of 89 players (60.6%) sustained an injury. The
overall injury incidence was 5 injuries per 1000 h of futsal play exposure.
Moderate injuries were the most frequent (1.7 injuries per 1000 h of futsal play
exposure). The quadriceps and ankle were the regions where most injuries
occurred. Contact injuries were more common during matches than training, and
usually happened at the end of the season. Elite female futsal players are
exposed to a substantial injury risk, especially on ankle and quadriceps with
moderate severity, occurring at the end of the sessions, especially during
matches. These results highlight the need of new preventive strategies to reduce
the high injury incidence in female futsal players.
Evidenz für TCM/Akupunktur bei SARS-CoV-2-Infektionen
Authors: Fleckenstein Johannes , Füzeki Eszter , Banzer Winfried 
Published: June 2020

SummaryDerzeit existiert keine spezifische Therapie zur Prävention und Behandlung von SARS-CoV-2-Infektionen, weder in der konventionellen westlichen noch in der Traditionellen Chinesischen Medizin. Die aktuelle Studienlage zur Anwendung der chinesischen Arzneitherapie bei SARS-CoV-2-Infektionen beruht überwiegend auf klinischen Beobachtungen und entspricht einem niedrigen Evidenzniveau (IV) mit Empfehlungsgrad C. Somit wäre ein additiver Einsatzchinesischer Arzneimittel zur Symptombesserung zwar zu rechtfertigen, dies jedoch nur unter konsequenter Einhaltung etablierter Erstmaßnahmen mit konventionellen Methoden der Intensiv- und Notfallmedizin und weiterer Verfahren der klassischen Medizin.
Indikationen für chinesische Arzneimitteltherapie bei Covid-19-Erkrankungen
Authors: Thede Christian 
Published: June 2020

SummaryIn Reaktion auf den massiven Ausbruch von Covid-19-Erkrankungen in der Region Wuhan wurde von staatlicher Seite bereits Ende Januar 2020 eine Expertenkommission namhafter chinesischer TCM-Fachleute berufen. Nach der Sichtung einer größeren Anzahl von Patienten in Wuhan wurdenTherapieprotokolle für verschiedene Krankheitsstadien formuliert, die in den „Guidance for Corona Virus Disease 2019“ des Generalbüros der Nationalen Hygiene und Gesundheitskommission und des Büros der staatlichen Verwaltung für traditionelle chinesische Medizin aufgenommen wurden.
5.2.30 Product Subclass 30: Stannoles
Authors: Ramirez y Medina I.-M. , Kipke W. , Makow J. , Staubitz A. 
Published: June 2020

AbstractThis chapter gives an overview of different methods for the synthesis of classical stannoles and related compounds such as ring-fused stannoles and stannoles containing further heteroatoms. It represents a review of the literature from 1959 to 2019.
32.3.4.2 1-Nitrogen-Functionalized 2-Haloalkenes (Update 2020)
Authors: Tong M. L. , Kunz K. , Jaschinski M. , Holzschneider K. , Celik I. E. , Kirsch S. F. 
Published: June 2020

AbstractThis chapter is an update to the earlier Science of Synthesis contribution (Section 32.3.4) describing general synthetic methods to access 1-nitrogen-functionalized 2-haloalkenes. It puts a new focus on recent synthetic developments for this rather broad class of compounds, covering the literature from 2008 until 2018. The contents are broadly categorized by discussing methods of synthesis first, followed by specific reactivities. The synthetic methods section is arranged according to the number of substituents attached to the alkene core. Due to the vast number of examples in the literature, the current overview represents a selection of methods. In particular, when describing reactivities with 1-nitrogen-functionalized 2-haloalkenes, only archetypical examples are shown, while explicit variants are omitted.
Whey protein supplementation in muscle hypertrophy
Authors: Sobral C , Gomes D , Silva M , Martins P , Baltazar A 
Published: June 2020

Abstract
Introduction The nutritional intake in the context of a hypertrophy training can affect body composition, the increase of muscle mass and strength. Whey protein seems to promote a reduction in body fat, improve hypertrophy, and other potential health benefits. This protein is one of the highest quality proteins due to its amino acid content (especially leucine) and to the rapid digestibility. Whey protein consumption has a robust ability to stimulate muscle protein synthesis. There are 3 types of whey protein: controlled, insulated and hydrolysed.
Objectives The goal of this research is verifying the efficacy of the use of whey protein supplementation in athletes seeking muscle strength and mass gain.
Methodology *
We analysed scientific articles from 2014 to 2019, based on Pubmed and Google scholar. Keywords such as whey protein, supplement, hypertrophy, muscle mass and nutrition were used.
Results From scientific research, six articles were analysed. Thus, it is estimated the analysis of 13 men under the age of 18 years and under 30 years of age. Only men with a percentage of fat mass less than or equal to 23% were selected. Two groups were created: the control group that consumed carbohydrate supplements and the experimental group that consumed 36g/day whey protein. Both groups performed 3 sessions/week of resistance training, and the used dose of protein derived from the diet was 1.4g/Kg/day. Both groups experienced gains in strength, 1 maxi (RM) and fat-free mass (FFM). However, the experimental group had an extra 9% and 27% in 1RM and FFM respectively compared to the control group.
Conclusion In short, supplementation with whey protein contributes to the increase of muscle mass and strength in athletes whose training (frequency, volume and duration) and diet are suitable for this purpose.
Assessment of Health Literacy Levels: HLS-EU-PT versus METER
Authors: Luís J , Rocha C , Balteiro J 
Published: June 2020

Abstract
Introduction The definition of this concept and its domains, as well as its measurement, will allow to identify health inequalities. And therefore focus the focus of professional intervention to ensure equitable access to health. The health literacy assessment tool should be based on the defined literacy concept and address the domains of the underlying theory, considering public health behaviours and outcomes. According to the European Consortium for Health Literacy, three dimensions of literacy are distinguished: functional literacy, interactive literacy and critical literacy.
Objectives To compare the health literacy levels obtained by applying two different measurement tools.
Methodology To assess Health Literacy levels were applied two tests: HLS-EU-PT (European Health Literacy Survey Questionnaire - Portugal) and METER (Medical Term Recognition Test). The first, quite comprehensive and previously used at European level, of self-perception, and the second more objective. These validated instruments were applied in a pharmacy in the municipality of Mealhada, to 377 individuals resident there.
Results HLS-EU-PT presents 40.8% of individuals with adequate literacy, while METER classifies 49.1% of the sample. There is a difference of 8.3% in the results. However, there is a statistically significant relationship between them (p = 0.001). METER is limited to the assessment of functional literacy levels. Too narrow a perspective for a concept as broad as health literacy. In this context, when measuring literacy is based on word recognition, limited levels of health literacy are found in 50.9% of individuals.
Conclusion Statistically, the two tests used present a significant correlation. Although METER misclassifies some individuals with adequate literacy who actually have inadequate literacy, this happens more often when the scores obtained are reduced. When the score on one test is high, on the other test, it also happens.
The immediate effect of vocal technique associated with virtual reality game in people with Parkinsons disease
Authors: Cruz T , Coriolano M , Silva H , Gomes A , Lira Z 
Published: June 2020

Abstract
Introduction People with Parkinson’s Disease (PD) have difficult motor hearing calibration, which affects the monitoring of vocal production. Therefore, employing visual stimulus associated with vocal therapy may benefit the voice of this population. For this purpose, some techniques favour the competence of the glottis, such as pushing, which consists of movements of the arms with a simultaneous effort to phonation and, associated with virtual reality games, provide playful therapeutic intervention through the simulation of experiences that can foster glottal adjustments and generate changes in the voice.
Objectives To determine the immediate effect of the technique of pushing with plosive sounds associated with the use of a virtual reality game in the voice of people with Parkinson's disease.
Methodology The participants were 17 men and 14 women, mean age of 62.61 (± 11.24) years, meantime of diagnosis 6.93 years, distributed in stages I (32.5%), II (22.59%), III (45.16%) of Hoehn and Yahr. scale. The vocal evaluation pre and post pushing technique with plosive sounds associated with virtual reality game consisted of analysing vocal, acoustic parameters from the record of the issuance of the vowel /ε/. The parameters extracted were Jitter, Shimmer, corresponding to signs of disturbance of the sound source and Glottal-to Noise Excitation (GNE), corresponding to the energy of the glottis on the noise. The satisfaction questionnaire on the implementation of this technique associated with virtual reality was used.
Results The values of disturbance of the sound wave decreased, and the glottal energy on the noise increased, respectively, Jitter (p = 0.0075); Shimmer (p = 0.0048); GNE (p = 0.0008). Regarding the satisfaction questionnaire, 74.20% of them felt very satisfied and 25.80%, satisfied.
Conclusion The vocal technique associated with virtual reality game improved the acoustic parameters of the participants' voice and the majority felt great satisfaction with the intervention.
Cross-cultural adaptation and validation of the VISA-A questionnaire for Portuguese-speaking (Portugal) patients with Achilles tendinopathy
Authors: Paço M , Rodrigues A , Oliveira C , Carvalho D , Ferreira J , Simões M , Araújo FA , Chaves P 
Published: June 2020

Abstract
Introduction Achilles tendinopathy is considered one of the most frequent injuries in individuals who practice regular physical activity, thus the existence of an instrument that allows the evaluation of the degree of severity of the lesion is important. The VISA-A was developed for English-speaking population to evaluate patients with this condition, and there is a need to adapt this tool to Portuguese (Portugal).
Objectives To cross-cultural adapt and validate the VISA-A questionnaire for Portuguese-speaking (Portugal) Achilles tendinopathy patients.
Methodology The VISA-A questionnaire was translated and cross-culturally adapted into Portuguese (VISA-A-Por) according to specific guidelines, using six steps: Translation, synthesis, back translation, expert committee review, pretesting (n = 10), and appraisal of the adaptation process. The resulting VISA-A-Por was then subjected to an analysis of the psychometric properties (construct validity, reproducibility [agreement and reliability], internal consistency and floor and ceiling effects) in 57 Achilles tendinopathy patients and 58 asymptomatic people. Participants completed the questionnaire at baseline and after a minimum interval of 48 hours.
Results The Visa-A-Por semantic and content validity was considered good by the expert committee and has construct validity shown by the differences between groups (p &lt; 0,001). The questionnaire presented good internal consistency, with a Cronbach α of 0,88. Concerning reproducibility, agreement levels were considered optimal which can be verified in the Bland Altman graph, the standard error measurement (6,49) and the minimally important change (17,99 points), as well as the excellent ICC value (0,88). No ceiling-floor effect was found.
Conclusion The VISA-A-Por questionnaire has been shown to be equivalent to the original questionnaire, which indicates that it is a valid and reliable measure for the evaluation of the severity and functional impact of patellar tendinopathy in Portuguese-speaking (Portugal) patients.
Wearable Sensor-Based Exercise Biofeedback for Supporting Fall Prevention at Physiotherapy
Authors: Martins A C , Guia D 
Published: June 2020

Abstract
Introduction Exercise interventions focused on strength and balance are effective for falls prevention in older people. Several fall prevention programs were developed with this intent, however there is often a lack of personalization in these solutions. Technological interventions namely biofeedback systems have been shown recently to have the ability to objectively assess therapeutic exercise in real time to improve quality performance.
Objectives To describe a technological solution with biofeedback system to be used by physiotherapists at the clinic, to assist the learning process of a personalized and progressive strength and balance exercise program.
Methodology The exercises are monitored by two wearable inertial sensors and a pressure platform for mobility, strength and balance measurements. In order to validate the system, a set of five exercises, from the Otago Exercise Program, were tested with a group of 16 older adults during several sessions. Spatial, temporal and balance metrics were extracted during the exercises, providing quantitative biofeedback during the exercise.
Results Inertial and pressure sensors are suitable for exercise tracking during fall prevention exercises. Range of motion, weight distribution and shifting, balance and cycle identification were successfully monitored for all exercises. This system successfully automated the process of creating individualized and personalized exercise biofeedback systems to fall prevention programs.
Conclusion This study demonstrates this technological solution holds promise in falls prevention. FallSensing Clinic is a feasible monitor and biofeedback tool that can be applied to clinical practice allowing people to better perform the exercise program.
Accessible communication in the transport of non-urgent people with communication impairments
Authors: Soares EM , Granjo T , Monteiro S , Bemposta S , Salvador A 
Published: June 2020

Abstract
Introduction Paramedics may find innumerous circumstances that require careful consideration of the patient’s clinical condition. Because of that, communication between paramedics and patients in a critical condition must be as clear and effective as possible.
Objectives This study aims to identify the communicative needs of ambulance’s crew members when transporting non-urgent people with communicative impairments and to create a tool that facilitates the communicative process.
Methodology A brainstorming was held at Associação de São Jorge to gather information regarding the needs and difficulties experienced by the ambulance’s crew members. An audio record of this meeting was collected and a qualitative analysis was carried out. Additionally, a questionnaire was fulfilled. Based on these results, a first version of the communicative tool was developed. A pluridisciplinary focus group was held to discuss it, regarding content, form and utility. After this focus group, the second version of the communicative tool was elaborated to be tested by the crew members of this association. As so, a dynamic of three hours was implemented to empower these professionals to use this tool and other communicative strategies.
Results The qualitative analysis of the first meeting collected data recognize as crew member’s needs: communicating basic and immediate needs at clinical level and at colloquial discourse. This data allowed to establish parameters for the construction of the first version of the communicative tool. The referred focus group identified the need to improve it, considering: format, content and also the need to complement this tool with other communicative facilitators (e.g. braille; gestures).
Conclusion This study shows the need of facilitating the communication in non-urgent transportation. Despite the modifications that have to be done, the communicative tool that was developed already shows a positive impact in the ambulance crew and in the community.
Cannabis Therapeutic Applications - Review
Authors: Faim J , Balteiro J 
Published: June 2020

Abstract
Introduction Medical cannabis refers to the use of cannabis or cannabinoids as medical therapy to treat disease or alleviate symptoms. Cannabinoids can be given orally, sublingually or topically, can be smoked, inhaled, mixed with food or made into tea.
Objectives Elaboration of a systematic literature review about cannabis’s medicinal and therapeutic properties. It is intended to characterize the plant and its properties, highlighting the proven therapeutic evidence published in the area of oncology and diseases of the central nervous system.
Methodology The selection of articles was based on the reading and analysis of the title and the abstract; only articles published in the last 15 years have been considered. After full analysis of the selected articles, it was concluded that 64 scientific articles were relevant to the study.
Results With this systematic review, we can conclude that its therapeutic application in areas such as epilepsy, multiple sclerosis and in the relief of some cancer patient’s symptoms is promising. Its apparent anti-tumour activity in various types of cancer is of increasing scientific interest as current treatments in these situations are scarce.
Conclusion The future of cannabis therapy is getting closer. It is therefore necessary to study and develop new synthetic analogues of THC, with better separation between therapeutic and side effects. Scientific advances show that Cannabis sativa is a treatment option for many conditions. With this systematic review we can conclude that its therapeutic application in areas such as epilepsy, multiple sclerosis and in the relief of some symptoms in cancer patients is promising. Its apparent anti-tumour activity in various types of cancer is also of increasing scientific interest.
Comparison between two databases regarding the classification of Drug Interactions and their mechanism of action
Authors: Fernandes D , Jesus A 
Published: June 2020

Abstract
Introduction Many drug-related problems are caused by drug interactions (DIs) that result from the pharmacological influence of one drug on another when taken together. DIs may have beneficial and predictable effects, but may also cause undesirable results, such as treatment ineffectiveness or serious adverse effects. There are a number of available databases with information about DIs. Although the information they provide is not always consensual, it is a useful tool in analysing the occurrence of potential drug interactions (PDIs) and in preventing unwanted or even fatal consequences for patients.
Objectives To compare the convergence of two databases (Micromedex/Drugs.com) regarding the classification of DIs and their mechanism of action.
Methodology A cross-sectional, descriptive and exploratory observational study was carried out using prescriptions from users with diabetes, dyslipidaemia or both pathologies from pharmacies in two districts, Porto and Braga. Information from each sample group was further analysed using two databases, Micromedex/Drugs.com.
Results Of the 57 pairs whose interaction potential was analysed, 64.3% converged on the classifications in both databases. Micromedex assigns moderate potential interaction to 36 drug pairs, and of these, 28 get the same rating on Drugs.com. Regarding the major PDIs, the degree of agreement was 40%. There are 4 drug pairs with potential for major interaction at Micromedex to which Drugs.com assigns moderate PDI. Minor PDIs were found on Drugs.com in 4 drug pairs, which Micromedex rated as major or moderate. For the remaining twelve divergent rating pairs, Drugs.com does not assign them potential for interaction while Micromedex gives them potential for major or moderate PDIs. Regarding the consequences of the occurrence of PDIs, there is agreement between Micromedex and Drugs.com, except for pair AAS/Loop Diuretics.
Conclusion Micromedex identifies a higher number of PDIs and assigns higher severity to a higher number.