bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical impact of leakage in patients with handsewn vs stapled anastomosis after right hemicolectomy: a retrospective study
Authors: Espin E. , Vallribera F. , Kreisler E. , Biondo S. 
Published: April 2020

AbstractAimAnastomotic leakage is a major complication after right hemicolectomy leading to increased morbidity, mortality, length of stay and hospital costs. Previous studies have shown that the type of anastomosis (handsewn or stapled) is a major risk factor for anastomotic leakage. The purpose of this study was to evaluate the clinical impact of anastomotic leakage depending on the type of anastomotic technique (handsewn vs stapled).MethodThis was an observational, retrospective, cross‐sectional study. Data were collected at two major hospitals in Spain from January 2010 to December 2016. Patients had elective right colectomy for cancer with handsewn or stapled ileocolic anastomosis. The main outcome was the grading of postoperative treatments needed to manage anastomotic leakage according to two major classification systems. The other outcomes were demographics, time of hospitalization and death rate.ResultsPatients (n = 961) underwent elective surgery for neoplasia of the right colon. Anastomotic leakage was diagnosed in 116 patients (12.07%). Patients with handsewn anastomosis had more Type IIIA surgical complications and received milder treatments than patients with stapled anastomosis (SA) who had more Type IIIB complications and more re‐laparotomies (P = 0.004). The clinical impact of anastomotic leakage was significantly more severe (Grade C) in patients with SA than in patients with a handsewn anastomosis (P = 0.007). No differences were found for hospital stay of patients with anastomotic leakage depending on the type of anastomosis (P = 0.275). Death due to anastomotic leakage was similar in both groups.ConclusionsThe clinical impact of anastomotic leakage in patients with handsewn anastomosis is lower than in patients with SA.
Niche partitioning among three montane ground‐dwelling pheasant species along multiple ecological dimensions
Authors: Wang Bin , Xu Yu , Price Megan , Yang Nan , Liu Wei , Zhu Bowei , Zhong Xue , Ran Jianghong 
Published: April 2020

Pheasants (order Galliformes) are typical ground‐dwelling birds, having a large body size and weak flight abilities. Sympatric pheasants are expected to share narrower niche space and face more extensive interspecific competition. However, little work has been undertaken simultaneously to investigate niche partitioning among sympatric pheasant species across multiple ecological dimensions. We compared microhabitat use, activity pattern and foraging strategy of sympatric Blood Pheasant Ithaginis cruentus, Buff‐throated Partridge Tetraophasis szechenyii and White Eared‐pheasant Crossoptilon crossoptilon on the Qinghai‐Tibet Plateau, China, to identify potential interspecific niche partitioning along different ecological dimensions in the breeding season. We found that the Buff‐throated Partridge differed significantly from the other two species in microhabitat use, and the three species showed different foraging strategies. It is likely that niche partitioning reduced potential interspecific competition, thus facilitating the species’ stable coexistence. Our study provides practical evidence of multidimensional niche theory within sympatric ground‐dwelling pheasant species, emphasizing that species interactions and coexistence within a guild are often not uni‐dimensional. Given global conservation concern for maintaining bird diversity, we recommend further restriction of yak grazing in these species’ habitat.
Sources of parasitic features in the visible range of oxide transparent ceramics absorption spectra
Authors: Goldstein Adrian , Katz Michael , Boulesteix Rémy , Shames Alexander I. , Coureau Christope , Raethel Jan , Mateos‐Ferre Xavier , Loiko Pavel 
Published: April 2020

AbstractThis research focused on the identification of parasitic signal sources introduced by sintering under reductive atmospheres of oxide transparent ceramics. The examination encompassed a wide set of materials, like Mg‐spinel, magnesia, alumina. YAG, yttria, zirconia and titania, so as to allow one to detect general rules if operating. The main finding is the dependence between the ability of such ceramics to generate, under reductive conditions, intrinsic parasitic light‐absorbing centers and their composition and structure. Thus it was determined that oxides based on transition element cations have ,in this sense, abilities not present in the case of oxides of elements from the main periodic table groups. The reason is the possibility of non‐absorbing transition cations to be reduced to oxidation states that absorb light. Drive toward reduced oxidation states is motivated by the stabilization energy associated with the ligand fields acting upon the such cations. It has been also found out that YAG lattice distortion, by dopants like tetravalent silicon or zirconium facilitates reduction of Y 3+ to Y 2 + (a light absorbing, d1, cation).Oxygen vacancies do not significantly influence visible light absorption. Carbon atoms penetrate inside ceramics, even dense ones and cause achromatic tints formation.
Multi‐centre retrospective study of the long‐term outcome following suspected traumatic elbow luxation in 32 cats
Authors: Williams H. , Calvo I. , Gaines A. , Kalff S. , Sajik D. , Kulendra N. J. , Meeson R. L. , Parsons K. , Farrell M. , Kulendra E. R. 
Published: April 2020

ObjectivesTo describe reduction techniques and clinical outcome in a series of traumatic elbow luxations in cats.Materials and MethodsRetrospective review of unilateral elbow luxations treated at five specialist referral centres. Data included signalment, aetiology, concurrent injuries, luxation direction, time to reduction, primary reduction technique, surgical procedure and complications. Cases were excluded if reduction technique was unknown. Telephone owner questionnaire follow‐up was completed using a Feline Musculoskeletal Pain Index.ResultsThirty‐two cats were included. Lateral luxations were most common (n = 21). Time (hours) until attempted initial closed reduction was <24 (n = 12), 24–48 (n = 13), >48 (n = 3) or unrecorded (n = 4). Luxation was treated by closed reduction alone (n = 7) or by surgery (n = 25); 14 of 25 cases underwent primary surgical reduction and 11 of 25 were secondary procedures following failure of closed reduction. Transcondylar bone tunnels and circumferential suture (n = 19) was the most commonly used surgical technique. Catastrophic (n = 1), major (n = 11) and minor complications (n = 5) were recorded; reluxation occurred more frequently after closed reduction (n = 8) than after open reduction with fixation (n = 0). Feline Musculoskeletal Pain Index data were available for 12 cats; outcome was good‐excellent in all 12, with a median function score of 64.5/68 (range: 55–68) and a median pain score of 0/15 (range: 0–5). Outcome was not associated with reduction technique.Clinical SignificanceElbow reluxation occurred in 61% of cats following primary closed reduction but did not occur in any open reduction cases. Reluxation rate increased with duration from injury. Most cats had good‐excellent owner‐assessed outcome, regardless of reduction technique.
Lymphocytosis and lymphadenopathy in a dog arising from two distinct lymphoid neoplasms
Authors: Long Mackenzie E. , Evans Brittany , Avery Anne C. , Wellman Maxey L. 
Published: April 2020

AbstractA 10‐year‐old intact male Golden Retriever was presented to The Ohio State University Veterinary Medical Center for acute, non‐painful facial swelling of the right mandibular region. On physical examination, the right mandibular swelling was found to represent marked lymphadenopathy of the submandibular lymph node. At this time, marked lymphadenopathy of the prescapular and popliteal lymph nodes was also appreciated. The CBC showed a moderate leukocytosis (38.4 × 109 cells/L, reference interval [RI] 4.8‐13.9 × 109 cells/L) characterized by a moderate lymphocytosis (28.4 × 109 cells/L, RI 1.0‐4.6 × 109 cells/L). Evaluation of peripheral blood and enlarged prescapular and popliteal lymph nodes revealed two morphologically different populations of homogeneous lymphocytes, with the lymphocyte population in the lymph nodes being distinct from that in the blood smear. Flow cytometry of peripheral blood revealed CD45‐, CD5+, CD4‐, CD8‐, variably CD21+ neoplastic lymphocytes compatible with T‐zone lymphocytes due to the absence of CD45 expression. Flow cytometry of the lymph node aspirate indicated a distinct population of CD21+ lymphocytes consistent with a B‐cell phenotype along with a smaller proportion of the T‐zone lymphocytes observed in the blood confirming the presence of two distinct populations of neoplastic lymphocytes, one involving T cells, and the other involving B cells.
Reliability testing of the Matching Assessment using Photographs of Scars App
Authors: Klotz Tanja , Kurmis Rochelle 
Published: April 2020

AbstractThe Matching Assessment using Photographs with Scars assessment tool, published in 2005, enables accurate relocation and reassessment of scars. While used in Australia, uptake has been hampered by its paper manual format. With electronic records and increasing use of smart devices in health, here we report the development of the Matching Assessment using Photographs with Scars manual into a mobile application format: ClinMAPSTM Pro. At the time of development, no other digital scar assessment applications were available. For clinical validation, the digitized Matching Assessment using Photographs with Scars module within ClinMAPSTM Pro was used for intra‐ and inter‐rater reliability testing. Convenience sampling was utilized to recruit burns patients representing 44 scars, based on predetermined power calculations. Three therapists, one experienced and two novice, acted as the assessors. Each therapist assessed preselected scars with the digitized Matching Assessment using Photographs with Scars. Re‐assessment of the same scar sites occurred 3 to 7 days later. Inter‐rater reliability testing scores of the new electronic assessment application showed fair to moderate agreement (combined Fleiss Kappa = 0.38‐0.49, P < .0001). Intra‐rater reliability scores between initial and repeat measures showed moderate to almost perfect agreement (Cohen's Kappa = 0.43‐0.90, P < .0001). It was noted that for an experienced rater, intra‐rater agreement demonstrated substantial to almost perfect agreement. Intraclass correlation coefficients calculated to allow for comparison between other published scar assessment tools demonstrated excellent reliability for all scar assessment parameters for both intra‐ (=0.76‐0.91) and inter‐ (=0.76‐0.98) reliability. Notably, reliability testing results confirm its intra‐ and inter‐rater reliability. Our findings validate this novel concept for digitization of the previously paper‐based scar assessment manual and prove that the Matching Assessment using Photographs with Scars within the ClinMAPSTM Pro application is now readily available for clinicians and researchers internationally.
Reviewer Acknowledgements
Authors: Young James 
Published: April 2020

International Journal of Social Science Studies (IJSSS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether IJSSS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 8, Number 3Agboola O. Paul, Universiti Teknologi Malaysia, MalaysiaAna Uka, Beder University, AlbaniaAntónio Calha, Polytechnic Institute of Portalegre, PortugalAslan,Yasin, Sinop University, TurkeyBegoña Montero-Fleta, Universitat Politécnica de València, SpainEmilio Greco, Sapienza University of Rome, ItalyEncarnación ABAD ARENAS, National University of Distance Education (UNED), SpainHao Liu, Beijing Normal University, ChinaJehu Onyekwere Nnaji, University of Naples II,Italy and Globe Visions Network Italy, ItalyJuanita GOICOVICI, University Babeș-Bolyai of Cluj-Napoca, RomaniaK.O. Aramide, The Polytechnic Ibadan, NigeriaLaura Diaconu Maxim, "Alexandru Ioan Cuza University" of Iasi, RomaniaMei-Ling Lin, National Open University, TaiwanMickey Langlais, University of Nebraska – Kearney, USAQingzhi Huan, Peking University, ChinaRachita Shrivastava Roy, Department of Higher Education, Chhatisgarh-India, IndiaRonaldo R. Larioque, NUEVA ECIJA UNIVERSITY OF SCIENCE AND TECHNOLOGY, PhilippinesUğur DEMİRCİ, Turkish National Police, TurkeyYusramizza Md Isa, Universiti Utara Malaysia, MalaysiaZlatan Begić, University of Tuzla, Bosnia and Herzegovina James YoungEditorial AssistantOn behalf of,The Editorial Board of International Journal of Social Science StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://ijsss.redfame.com
Limitations to Freedom of Religion or Belief in Georgia: Legislation and State Policy
Authors: Chitanava Ekaterine , Gavtadze Mariam 
Published: April 2020

Abstract
This article demonstrates legal and non-legal limitations of freedom of religion or belief (FoRB) in Georgia, characterized by an absence of relevant case law of common courts about restrictions to FoRB with legitimate aims. Instead, the State is using various instruments for interference, such as administrative barriers and artificial obstacles for religious communities. In certain occasions, its policy and practice do not comply with the constitutional principles and international human rights commitments of the country. The State’s preferential treatment of the dominant and influential religious institution, the Georgian Orthodox Church, ostracises other religious communities. This is further aggravated by the attempts of securitising and weaponising FoRB.
Opinion on Current Use of Non-Blinded Versus Blinded Histopathologic Evaluation in Animal Toxicity Studies
Authors: Bolon Brad , Caverly Rae Jessica M. , Colman Karyn , Francke Sabine , Jensen Karl , Keane Kevin , McInnes Elizabeth F. , Nakano-Ito Kyoko , Perry Rick , Polack Evelyne , Regan Karen S. , Romeike Annette , Young Jamie K. , Galbreath Elizabeth J. 
Published: April 2020

The Society of Toxicologic Pathology (STP) explored current institutional practices for selecting between non-blinded versus blinded histopathologic evaluation during Good Laboratory Practice (GLP)-compliant, regulatory-type animal toxicity studies using a multi-question survey and STP-wide discussion (held at the 2019 STP annual meeting). Survey responses were received from 107 individuals representing 83 institutions that collectively employ 589 toxicologic pathologists. Most responses came from industry (N = 46, mainly biopharmaceutical or contract research organizations) and consultants (N = 24). For GLP-compliant animal toxicity studies, histopathologic evaluation usually involves initial (primary) non-blinded analysis, with post hoc informal blinded re-examination at the study pathologist’s discretion to confirm subtle findings or establish thresholds. Initial blinded histopathologic evaluation sometimes is chosen by study pathologists to test formal hypotheses and/or by sponsors to address non-pathologist expectations about histopathology data objectivity. Current practice is that a blinded histopathologic evaluation is documented only if formal blinding (ie, using slides with coded labels) is employed, using simple statements without detailed methodology in the study protocol (or an amendment) and/or pathology report. Blinding is not an appropriate strategy for the initial histopathologic evaluation performed during pathology peer reviews of GLP-compliant animal toxicity studies. [Box: see text]
One-year outcomes of the Polish treatment program for the wet form of age-related macular degeneration using intravitreal therapy
Authors: Figurska Małgorzata , Matysik-Wożniak Anna , Adamiec-Mroczek Joanna , Dolar-Szczasny Joanna , Misiuk-Hojło Marta , Teper Sławomir , Święch-Zubilewicz Anna , Ulińska Magdalena , Rejdak Robert , Rękas Marek 
Published: April 2020

Purpose: To report 12-month outcomes of a Polish National Treatment Program using aflibercept and ranibizumab in eyes with wet, age-related macular degeneration in routine clinical practice. Material and Methods: This was a non-randomized, retrospective, observational multicenter study. Anonymous data contained in the electronic Therapeutic Program Monitoring System were utilized in this study. Results: The study population consisted of 2828 eyes from 2718 patients. The median age was 76.0 [70.0, 81.0] years; 61.7% were female. Best corrected visual acuity increased from 58.86 [50.05, 69.95] letters to 65.1 [50.1, 73.9] letters (p < 0.001). The median change in best corrected visual acuity was 0.0 [−4.0, 12.2] letters: 2.9 [−2.9, 15.1] letters for treatment-naïve eyes and 0.0 [−4.0, 8.8] letters for those continuing treatment (p < 0.001). The median central retinal thickness was significantly reduced from 341.0 [281.0, 422.0] to 275.0 [221.0, 344.0] μm (p < 0.001). The median number of visits was 9.0 [8.0, 9.0]. The median number of injections was 7.0 [6.0, 8.0]: 8.0 [7.0, 8.0] for treatment-naïve eyes and 6.0 [5.0, 7.0] for those continuing treatment (p < 0.001). Conclusion: Eyes treated as part of the Polish therapeutic program gained functional stability and morphological improvement. Treatment-naïve eyes showed the greatest functional benefit.
Non-invasive estimation of stroke volume during exercise from oxygen in heart failure patients
Authors: Accalai Emanuele , Vignati Carlo , Salvioni Elisabetta , Pezzuto Beatrice , Contini Mauro , Cadeddu Christian , Meloni Luigi , Agostoni Piergiuseppe 
Published: April 2020

Abstract

Aims
In heart failure, oxygen uptake and cardiac output measurements at peak and during exercise are important in defining heart failure severity and prognosis. Several cardiopulmonary exercise test-derived parameters have been proposed to estimate stroke volume during exercise, including the oxygen pulse (oxygen uptake/heart rate). Data comparing measured stroke volume and the oxygen pulse or stroke volume estimates from the oxygen pulse at different stages of exercise in a sizeable population of healthy individuals and heart failure patients are lacking.

Methods
We analysed 1007 subjects, including 500 healthy and 507 heart failure patients, who underwent cardiopulmonary exercise testing with stroke volume determination by the inert gas rebreathing technique. Stroke volume measurements were made at rest, submaximal (∼50% of exercise) and peak exercise. At each stage of exercise, stroke volume estimates were obtained considering measured haemoglobin at rest, predicted exercise-induced haemoconcentration and peripheral oxygen extraction according to heart failure severity.

Results
A strong relationship between oxygen pulse and measured stroke volume was observed in healthy and heart failure subjects at submaximal (R2 = 0.6437 and R2 = 0.6723, respectively), and peak exercise (R2 = 0.6614 and R2 = 0.5662) but not at rest. In healthy and heart failure subjects, agreement between estimated and measured stroke volume was observed at submaximal (–3 ± 37 and –11 ± 72 ml, respectively) and peak exercise (1 ± 31 and 6 ± 29 ml, respectively) but not at rest.

Conclusion
In heart failure patients, stroke volume estimation and oxygen pulse during exercise represent stroke volume, albeit with a relevant individual data dispersion so that both can be used for population studies but cannot be reliably applied to a single subject. Accordingly, whenever needed stroke volume must be measured directly.
Evaluation of Nottingham Hip Fracture Score, Age-Adjusted Charlson Comorbidity Index and the Physiological and Operative Severity Score for the enumeration of Mortality and morbidity as predictors of mortality in elderly neck of femur fracture patients
Authors: Nelson Michael James , Scott Justin , Sivalingam Palvannan 
Published: April 2020

Background: This study evaluated the use of several risk prediction models in estimating short- and long-term mortality following hip fracture in an Australian population. Methods: Data from 195 patients were retrospectively analysed and applied to three models of interest: the Nottingham Hip Fracture Score, the Age-Adjusted Charlson Comorbidity Index and the Physiological and Operative Severity Score for enUmeration of Mortality and Morbidity. The performance of these models was assessed with receiver operating characteristic curve as well as logistic regression modelling. Results: The median age of participants was 83 years and 69% were women. Ten percent of patients were deceased by 30 days, 25% at 6 months and 31% at 12 months post-operatively. While there was no statistically significant difference between the models, the Age-Adjusted Charlson Comorbidity Index had the largest area under the receiver operating characteristic curve for within 30 day and 12 month mortality, while the Nottingham Hip Fracture Score was largest for 6-month mortality. There was no evidence to suggest that the models were selecting a specific subgroup of our population, therefore, no indication was present to suggest that using multiple models would improve mortality prediction. Conclusions: While there was no statistically significant difference in mortality prediction, the Nottingham Hip Fracture Score is perhaps the best suited clinically, due to its ease of implementation. Larger prospective data collection across a variety of sites and its role in guiding clinical management remains an area of interest.
From transformation to chronification of migraine: pathophysiological and clinical aspects
Authors:   On behalf of School of Advanced Studies of European Headache Federation (EHF-SAS), Torres-Ferrús M. , Ursitti F. , Alpuente A. , Brunello F. , Chiappino D. , de Vries T. , Di Marco S. , Ferlisi S. , Guerritore L. , Gonzalez-Garcia N. , Gonzalez-Martinez A. , Khutorov D. , Kritsilis M. , Kyrou A. , Makeeva T. , Minguez-Olaondo A. , Pilati L. , Serrien A. , Tsurkalenko O. , Van den Abbeele D. , van Hoogstraten W. S. , Lampl C. 
Published: April 2020

AbstractChronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chronification. Ample studies have attempted to identify factors associated with migraine transformation from different perspectives. Understanding CM as a pathological brain state with trigeminovascular participation where biological changes occur, we have completed a comprehensive review on the clinical, epidemiological, genetic, molecular, structural, functional, physiological and preclinical evidence available.