bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergency surgeries for rectal cancer complicated by intestinal obstruction: long-term outcomes and prognostic factors
Authors: Shchaeva S. N. , Kazantseva E. A. , Gordeeva E. V. 
Published: August 2020

The aim of the study: to examine the indicators of relapse-free survival and evaluate prognostic factors that had the greatest impact on relapse- free survival in patients with rectal cancer complicated by obstructive obstruction and undergoing emergency surgery.Materials and methods. The analysis of the immediate and long-term results of treatment – relapse-free survival of patients undergoing emergency surgery for rectal cancer complicated by obstructive obstruction in general surgical and specialized hospitals in Smolensk from 2001 to 2017 is presented. Relapse-free survival was analyzed by the Kaplan–Meier method. To determine the influence of potential risk factors on the rate of occurrence of the studied event, Cox regression was used.Results. Postoperative complications of the III–IV degree according to Clavien–Dindo were more common in patients undergoing emergency surgery for complicated rectal cancer in general surgical hospitals (p = 0.0056). In specialized hospitals, anastomosis leakage in 5.3 % (1 of 19 cases), in general surgical hospitals – 16.3 % (9 of 55 cases). Five-year relapse-free survival in general surgical hospitals at the IIB stage was 18.3 %, median survival – 32 months; in specialized hospitals at stage IIB 5‑year relapse-free was 45.8 %, median survival – 52 months (p = 0.028 and 0.011, respectively). A multivariate analysis confirmed the influence of the following factors on the performance of a 5‑year relapse-free survival: hospital specialization (risk ratio (RR) 1.35; 95 % confidence interval (CI) 1.18–1.55; p <0.001), type of surgery – one-stage operations (RR 1.13; 95 % CI 1.05–1.22; p = 0.001), the presence of metastases in the lymph nodes (RR 0.77; 95 % CI 0.71–0.84; p <0.0001), the number of examined lymph nodes (RR 0.79; 95 % CI 0.72–0.87; p <0.001).Conclusions. It is advisable to carry out two-stage surgical treatment with the formation of a colostomy at the first stage; the main stage of radical intervention should be performed in a specialized hospital.
Treatment monitoring of locally advanced rectal cancer based on multiparametric magnetic resonance tomography
Authors: Grishko P. Yu. , Mishchenko A. V. , Ivko O. V. , Samsonov D. V. , Karachun A. M. 
Published: August 2020

Objective: to determine the predicting factors for the effectiveness of neoadjuvant treatment in colorectal cancer based on the analysis of overall and relapse-free survival, as well as the possibility of multiparametric magnetic resonance imaging (MRI) in stratifying patients into groups with favorable and unfavorable clinical course.Materials and methods. 112 patients who received preoperative chemoradiotherapy (n = 85) and chemoradiotherapy supplemented with neoadjuvant polychemotherapy (n = 27) followed by surgery were enrolled in retrospective study. To determine the most significant predicting factors and criteria for evaluating the effectiveness of treatment that affect overall and relapse-free survival, Kaplan–Meier estimator and Cox regression were used.Results. The relapse-free survival was significantly affected by the presence or absence of extramural venous invasion according to MRI (mrEMVI) (p = 0.0001), circumferential resection margin status according to pathomorphological data (pCRM) (p = 0.031), change in volume of tumor (mrVolumetric analysis) (p = 0.015), tumor regression grade according to MRI (mrTRG) (p = 0.017) and pathomorphological data (pTRG) (p = 0.038). Independent predictors of overall survival were: extramural venous invasion according to MRI (mrEMVI) (p = 0.0001), posttreatment N staging (p = 0.047) and tumor regression grade according to MRI (mrTRG) (p = 0.059). Based on the most significant MR criteria, a mathematical model was developed to predict the risk of relapse after neoadjuvant treatment.Conclusions. MRI allows stratifying patients into groups with a favorable and unfavorable prognosis at the preoperative stage and optimizing the management of patients after surgery taking into account pathomorphological data.
Advanced distal rectal cancer: possibilities of sphincter-sparing surgeries in combination with neoadjuvant therapy
Authors: Barsukov Yu. A. , Tkachev S. I. , Mamedli Z. Z. , Vlasov O. A. , Aliev V. A. , Perevoshchikov A. G. , Goncharov S. V. 
Published: August 2020

Objective: to analyze the outcomes of sphincter-sparing surgeries in patients with advanced distal rectal cancer depending on the therapy they receive.Materials and methods. This study included 289 patients with advanced (stage T3N0–2M0) distal rectal cancer who have undergone sphincter-sparing surgeries. Patients were divided into three groups according to their treatment scheme. In group 1, we used combination treatment that included a short course of neoadjuvant radiotherapy supplemented by 3 multidirectional radiomodifiers (local microwave hyperthermia, rectal administration of a biopolymer composition containing metronidazole, and chemotherapy with capecitabine). Patients in group 2 received combination treatment that included neoadjuvant radiotherapy alone. Treatment outcomes in patients receiving combination therapy was compared to those of patients with similar characteristics and location of rectal tumors who have undergone surgery alone in N. N. Blokhin National Medical Research Center of Oncology (group 3).Results. We observed a significant decrease in the incidence of locoregional cancer metastasis in patients from group 1 compared to those from groups 2 and 3 (0.8 % vs 7.9 % and 18.2 % respectively). Moreover, patients in group 1 demonstrated better relapse-free survival than participants in groups 2 and 3 (79.6 % vs 52.6 % and 51 % respectively). The new scheme of combination therapy developed by our team (used in group 1) did not increase the incidence of postoperative complications. The best local disease control in group 1 was achieved in patients with middle rectal cancer who have undergone sphincter-sparing surgeries: none of 81 patients developed relapses, whereas the relapse-free survival rate reached 83 % compared to 56.9 % in group 1 and 41.7 % in group 3.Conclusions. The new treatment scheme that includes neoadjuvant radiotherapy supplemented by 3 multidirectional radiomodifiers can be used as one of the options increasing efficacy of radiotherapy and, therefore, efficacy of combination treatment in patients with advanced rectal cancer who undergo sphincter-sparing surgeries.
The safety of intracorporeal anastomoses after right colectomy during the learning curve
Authors: Melnikov P. V. , Chernikovskiy I. I. , Kanner D. Yu. , Savanovich N. V. , Gavrilyukov A. V. , Chernikov D. A. , Markushin L. I. 
Published: August 2020

Objective: to asses safety of installation intracorporeal anastomosis (ICA) in routine practice at learning curve period.Materials and methods. The results of treatment of 102 patients during 2019 were retrospectively analyzed, of which 64 were operated by an expert and 38 passing the ICA learning curve.Results. The operation time was shorter for the expert (145 minutes versus 210 minutes, p <0.05), there was no statistical difference in pathomorphological measurements, the number of lymph nodes removed was oncologically acceptable and did not differ significantly in the two groups. The total number of complications was 25.2 % for all patients, and Clavien–Dindo class IIIB complication rate was also the same (3.2 % vs 2.6 %, p >0.05).Conclusions. The introduction of ICA in right colectomy into routine practice at the stage of passing the learning curve is safe and applicable.
The liver-first approach in treatment of rectal cancer patients with synchronous liver metastases
Authors: Aliev V. A. , Dudaev Z. A. , Mamedli Z. Z. , Podluzhnyy D. V. , Tikhonov P. A. , Kononets P. V. 
Published: August 2020

Objective: to evaluate feasibility and short-term results of the liver-first approach in our center.Materials and methods. Retrospective study of prospectively gathered group of patients who were treated in N. N. Blokhin National Medical Research Center of Oncology between 2017 and 2019. Patients with asymptomatic primary tumor located in rectum and rectosigmoid junction with synchronous resectable / borderline resectable metastasis in liver. 22 patients were planned to undergo the liver-first approach. Post-operative morbidity and mortality (Clavien–Dindo) as well as tumor regression grading (Dworak) were evaluated.Results. Of the 17 patients planned to undergo the liver-first strategy, the approach was completed in 15 (88,2 %) patients. The main reason for treatment failure was disease progression. Post-operative morbidity and mortality were 13,3 % and 0 %, respectively.Conclusions. Liver-first approach is justified in two cases: during waiting period after last day of chemoradiotherapy in patients with locally advanced (invasion depth T4a, positive circumferential resection margin, N+ status) mid-to-low rectal cancer and in patients with multiple borderline resectable bilobar liver damage.
role of telehealth services in the treatment of rare disease: analysis of 1 year of work on the example of anal cancer
Authors: Gordeev S. S. , Fedyanin M. Yu. , Glazkova E. V. , Amosova V. A. , Petrovskiy A. V. 
Published: August 2020

Objective: to assess the potential need for telehealth consultations in regions for the treatment of patients diagnosed with anal cancer and to analyze the most common treatment errors. Materials and methods. We analyzed telehealth consultations provided for 3 Federal districts between April 2019 and April 2020. The following parameters were evaluated: the ratio between the predicted need for telehealth consultations and the real number of requests, the number of medical errors in patients who had already undergone first and / or subsequent treatment stages (according to relevant clinical guidelines). Results. Fifteen telehealth consultations were provided during this year: 13 of them (86.7 %) for disease progression or complications and 2 of them (13.3 %) to determine the initial treatment strategy. Treatment errors were registered in 11 out of 13 cases (84.6 %). The predicted need based on the population size was 565 consultations per year; the predicted need based on the real number of patients visited cancer clinics was 81 consultations. Conclusions. We found many significant errors in treatment regimens of patients with squamous cell anal carcinoma. Wider use of telehealth consultations with Federal centers will ensure the correct choice of the initial treatment strategy.
Colorectal cancer metastases to the lungs: outcomes of surgical treatment and prognostic factors
Authors: Akhmedov B. B. , Kononets P. V. , Fedyanin M. Yu. , Mamedli Z. Z. , Gordeev S. S. , Aliev V. A. , Stilidi I. S. 
Published: August 2020

Objective: to evaluate short-term and long-term outcomes of surgical treatment for colorectal cancer metastases to the lungs and to analyze factors affecting the efficacy of surgery. Materials and methods. This study included 211 patients with colorectal cancer metastases to the lungs treated between 1994 and 2014. We enrolled patients with resectable or conventionally resectable metastases (according to chest computed tomography evaluated by a thoracic surgeon); the exclusion criteria were as follows: multiple primary tumors and age more than 85 years. We assessed the type of surgeries, frequency of R0 resections, incidence of postoperative complications, overall survival, and progression-free survival. Results. One hundred and sixty-two patients out of 211 (76.8 %) have undergone atypical lung resection. Forty-nine patients (23.2 %) have undergone pneumonectomy, bilobectomy, or lobectomy. The majority of patients (96.2 %) have had R0 resection, whereas 2.9 % of study participants have had R1 or R2 resections. One patient has undergone a trial surgery. Clinically significant postoperative complications were observed in 4 (2 %) patients; postoperative mortality was 0.5 % (1 case). The five-year overall survival rate was 52.7 %; the 5-year progression-free survival rate was 45.8 %. Development of metastases within 24 months after primary surgery was found to be a significant factor negatively affecting overall survival (hazard ratio 0.347; 95 % confidence interval 0.227–0.53; р <0.0001). Conclusions. Surgical treatment is currently the only truly effective treatment, which can improve long-term survival of patients with colorectal cancer metastases to the lungs; the best treatment results are achieved in patients with a relapse-free interval of more than 24 months.
𝒃𝟐 Metrik Uzayında Çok Değişkenli Operatörler için Sabit Nokta Sonuçları Üzerine
Authors: AYDIN AKGÜN FATMA 
Published: August 2020

Bu çalışmanın amacı, 𝑏2 -metrik uzayında çok değişkenli operatörler için sabit nokta teoremi oluşturmak ve Chifu ve Petruşel (2017) ve Yihao, Ren ve Zhong (2018) sonuçlarını genelleştirmektir. Ayrıca, ana teoremi göstermek için bir örnek verilmiştir. Bu çalışmanın amacı, 𝑏2 -metrik uzayında çok değişkenli operatörler için sabit nokta teoremi oluşturmak ve Chifu ve Petruşel (2017) ve Yihao, Ren ve Zhong (2018) sonuçlarını genelleştirmektir. Ayrıca, ana teoremi göstermek için bir örnek verilmiştir.
Nilpotent Product of Parafree Lie Algebras and A Basis of This Product
Authors: VELİOGLU Zehra 
Published: August 2020

In this work, n-th nilpotent and
minimal nilpotent products of parafree Lie algebras are examined and it is
shown that these products are parafree. Also, a base set is obtained for the
n-th nilpotent products of two abelian Lie
algebras that are nilpotent of class n.In this work, n-th nilpotent and minimal nilpotent products of parafree Lie algebras are examined and it is shown that these products are parafree. Also, a base set is obtained for the n-th nilpotent products of two abelian Lie algebras that are nilpotent of class n. In this work, n-th nilpotent and minimal nilpotent products of parafree Lie algebras are examined and it is shown that these products are parafree. Also, a base set is obtained for the n-th nilpotent products of two abelian Lie algebras that are nilpotent of class n.
Işıklı Gölü ve Gökgöl Sulak Alanlarında Avrupa Doğa Bilgi Sistemi (EUNIS) Habitat Sınıflandırmasının Değerlendirilmesi
Authors: ÜRKER Okan , ÖZEN Arda 
Published: August 2020

Biyolojik çeşitliliği koruma çalışmaları
insanların barınma ve beslenme ihtiyaçlarına ve ekonomik gelişmelere genellikle
zıt düşmektedir. Ancak var olan kaynaklardan verimli ve sürdürülebilir bir
şekilde yararlanmayı sağlamak için her ülke kendi koşullarına göre, biyolojik
çeşitliliğinin belirlenmesine yönelik çalışmalarını tamamlamalıdır. Bu amaçla
Avrupa Birliği ülkeleri kolay ve anlaşılır bir sınıflandırma sistemi olan
Avrupa Doğa Bilgi Sistemi (EUNIS)’ni geliştirmişlerdir. Özellikle bitki
örtüsünün hâkim olduğu karasal ve iç su habitatların sınıflandırmasında temel
olarak bitki sosyolojisi, karasal küçük omurgalılar ve büyük omurgasızlara ait
verilerden faydalanılmaktadır. Bu çalışma Türkiye’nin önemli sulak alanlarından
biri olan ve su içi bitkileri bakımından zengin bir göl sistemi olan Denizli
İli, Çivril İlçesi’ndeki Işıklı gölü ve Gökgöl ve sulak alanlarında arazi
gözlemleri ve uydu görüntülerine
dayanılarak gerçekleştirilen örnek bir çalışmadır. Çalışma sonucunda Işıklı
Gölü ve Gökgöl sulak alanları ve yakın çevreleri EUNIS’e göre kodlanarak
sınıflandırılmıştır. Ayrıca bu çalışma özelinde; sulak alanlara yönelik yönetim
planları hazırlanma aşamalarında gerçekleştirilen habitat sınıflandırmalarının
hem koruma biyolojisi açısından hem de sulak alanın sürdürülebilir açıdan uzun
vadeli koruma-kullanma dengesini sağlamada önemli katkılar sunduğu da ortaya
konmuştur.
Black Music is American Music: Learning Underrepresented Aspects of Black History in College through Critical Race Media Literacy
Authors: Mitchell Patterson Tiffany , McWhorter Christine 
Published: August 2020

The New York Times 1619 Project materials on American popular culture were presented to college students at a Historically Black University & College (HBCU) and Predominantly White Institution (PWI). Guided by Critical Race Media Literacy, we employed quantitative and qualitative analysis to explore the knowledge-based and emotional responses to Black historical media. The findings suggest that HBCU and PWI students had similar levels of prior knowledge. HBCU and PWI students experienced disparate emotional responses to the material. Overall, both HBCU and PWI students’ knowledge increased on this topic following the study as the content is underrepresented in education and popular culture.
Pengelolaan Ekosistem Lamun untuk Keberlanjutan Populasi Kuda Laut di Desa Sebong Pereh, Kabupaten Bintan
Authors: Munandar Rizqan Khairan , Sulistiono Sulistiono , Setyobudiandi Isdrajad 
Published: August 2020

This research is about studying ecosystems that was designed to analyze the relationship between seagrass ecosystem, environmental competition, and seahorse participation to analyze the distribution of seagrass ecosystems and the abundance of sea horses, and to analyze seahorse-based ecosystem management strategies. This research was conducted in March–June 2017. The determination of the research station was based on purposive sampling technique. Retrieval of seagrass ecosystem data was conducted using a quadrant with the size of 50 x 50 cm transect. Seahorse data were collected using visual census on seagrass transect with a plot of 100 x 100 cm. The relationships between environmental parameters, seagrass ecosystems, and seahorses were calculated using XL Starting 2015. Management of seagrass ecosystems was analyzed using SWOT. Analysis of seagrass included type, density, and INP. Seahorse analysis calculated the abundance of seahorse. The results found 6 species of seagrasses, namely Enhalus acoraides (Ea), Thalassia hemprichii (Th), Halophila ovalis (Ho), Syringodium isoetifolium (Si), Cymodocea serrulata (Cs), and Thalassodendron ciliatum (Tc) with a density that covered sea horse abundance, and INP which had several types of roles in the research location. The management is carried out with the objectives of sustainable resources.

Keywords: seagrass ecosystem, seahorse, Sebong Pereh Village
Praktik Higiene Sanitasi dalam Pengelolaan Pangan di Sepuluh Industri Jasa Boga di Kota Bogor
Authors: Purnawita Widiati , Rahayu Winiati Pudji , Nurjanah Siti 
Published: August 2020

Catering industry is a food business which produces ready-to-eat food or food that will not be cooked or reheated before serving. Therefore, the safety of food produced by catering industry becomes very important. During period of 2015–2017, the food produced by catering industry was the third largest cause of food borne outbreak in Indonesia. This showed poor compliance level of food hygiene and sanitation in the catering industry, especially during food production. This study was aimed to measure the compliance level of sanitation and hygiene practices during food production in catering industries. This study was carried out in 10 catering industries located in Bogor City, consisting of 2 catering industries in class A2, 4 catering industries in class A3, and 4 catering industries in class B. Data collection was carried out by observation using checklist which was developed from Regulation of The Minister of Health Number 1096 Year 2011. Result showed that catering industries in class A2, A3, and B had an average compliance level of hygiene and sanitation practices during food production. The stage of raw material procurement in class A2 and stage of food processing in class A2, A3, and B were still in poor compliance level of hygiene and sanitation practices that should be more improved.

Keywords: catering industries, compliance level, hygiene and sanitation, food production
Penataan Rancangan Lokasi Instalasi Pengolahan Air Limbah Terpadu Kampus Institut Pertanian Bogor
Authors: Hariyadi Sigid , Tunjung Murti Pratiwi Niken , Krisanti Majariana , Panji Adham , Yuni Wulandari Dwi 
Published: August 2020

Until now there has not been a centralized Wastewater Treatment Plant (WWTP) in IPB, even though there are wastewater treatments in several locations that are scattered in the campus area. Various activities on the Dramaga IPB campus have the potential to produce wastewater, such as laboratory activities, especially chemical and biological laboratories, canteens, offices, and dormitories. The existence of scattered laboratories requires a centralized and integrated WWTP. For this reason, mapping of wastewater distribution is needed to arrange the location of the wastewater treatment plant, within the campus. Interviews with the perpetrators of activities, measurement of wastewater quality, and sampling, were carried out at the work units producing wastewater on the campus of IPB. The distribution of wastewater was grouped according to the location of the work units producing waste and identified the types of waste produced (B3-dangerous and toxic and non-B3), then presented in a map. The map was used as a reference in determining the location of wastewater treatment plants. The results showed that each work unit contributes organic waste that was not too different, the source of inorganic and B3 wastewater distribution followed the location of the laboratory which was also quite scattered in the Dramaga IPB campus area. Based on the distribution of available waste, the presence of wastewater in the campus environment of IPB was divided into two regional groups. Therefore, the location of the wastewater treatment plant was directed at two locations, namely on the Northeast side (IPAL I) and the West side (IPAL II) of IPB campus.

Keywords: wastewater characteristics, wastewater distribution, wastewater treatment plant
Land Value Potential Zonation : Implication Towards Urban Planning
Authors: Mainaki Revi , Putri Anita Eka , Utomo Dwiyono Hari 
Published: August 2020

Potential land prices are strongly influenced by various factors, Cimahi City has three sub-districts displaying unique characteristics, since it is located between two districts and one large city, which affects the potential price of land. The potential price of land is crucial to identify, especially in determining the policies of related agencies, the purpose of this research was to zoning potential land prices in Cimahi City. This study engaged a quantitative approach utilizing data collection technique in the form of observation, literature, documentation, and interviews, then analysis was conducted using a GIS which composed of assessment, weighting, coating, and buffering. The study population was all sub-districts in Cimahi. The research samples were taken from several sub-districts which were influenced by districts and cities characteristics indicators such as accessibility, land usage, and land ownership status. The results showed land prices potential was classified as low, medium, and high which was derived by several indicators. It could be concluded that the potential land price is strongly influenced by the surrounding area features, especially urban and district infrastructure.
Keywords: Land Value Potential; Zonation; Urban Planing
Copyright (c) 2020 Geosfera Indonesia Journal and Department of Geography Education, University of Jember
This work is licensed under a Creative Commons Attribution-Share A like 4.0 International License