bluuebunny/crossref_metadata_2025_split huggingface dataset:
MEMORIAS DE LA V REUNIóN ECUATORIANA DE ORNITOLOGíA
Authors: Ordóñez-Delgado Leonardo , Freile Juan F. , Guevara Esteban A. , Cisneros-Heredia Diego , Santander Tatiana 
Published: June 2020

Presentamos las memorias de la V Reunión Ecuatoriana de Ornitología (V REO), desarrollada en Zamora, en 11-14 Agosto 2016. La V REO contó con cinco charlas magistrales, un simposio sobre aves, café y cacao, 46 presentaciones orales y pósters, conversatorios sobre el Festival Mundial de las Aves, conteos navideños y Global Big Day, un taller de escritura científica, un taller de ilustración de aves en acuarela y una discusión abierta sobre la conformación de la Red Aves Ecuador. Contó con casi 150 participantes, entre expositores y asistentes.Palabras clave: Investigación, difusión, ornitología, conservación, Ecuador. Abstracts of the V Ecuadorian Ornithology MeetingAbstractWe present the abstracts of the V Ecuadorian Ornithology Meeting (V REO), held in Zamora, on 11-14 August 2016. The V REO included five plenary talks, a symposium on birds, coffee and cacao, 46 oral and poster presentations, round tables about the World Birds Festival, the Christmas bird counts and Global Big Days, a workshop on scientific writing, a workshop on bird illustration in watercolor, and an open discussion session about the creation of Red Aves Ecuador. Nearly 150 contributors and assistants participated in the V REO.Keywords: Conservation, divulgation, Ecuador, ornithology, research.
ANIDACIÓN DEL GORRIÓN CRIOLLO ZONOTRICHIA CAPENSIS (EMBERIZIDAE) EN QUITO, ECUADOR
Authors: Cadena-Ortiz Héctor 
Published: June 2020

Incrementar información sobre la biología reproductiva siempre es útil para evidenciar patrones. En este trabajo presento los detalles de un nido del Gorrión Criollo Zonotrichia capensis en forma de taza abierta, construido principalmente con fibras vegetales y una cubierta interior de pelos de mamífero, observado entre noviembre 2015 y julio 2016. El nido fue construido en un macetero colgante en una casa de un barrio céntrico de la ciudad de Quito. Dos huevos de color celeste pálido con manchas pardas fueron incubados durante 14 días. Estimé un periodo de 11 días de construcción del nido, 2 días de puesta y 14 de empollamiento.Palabras clave: Chingolo, huevos, incubación, nido, pichones, Quito, reproducción. Nesting of Rufous-collared Sparrow Zonotrichia capensis (Emberizidae) in Quito, EcuadorAbstractIncreasing information about the breeding biology of bird species is useful for evidencing patterns. In this study, I present observations of an open cup nest of Rufous-collared Sparrow Zonotrichia capensis, built primarily with plant fibers and an inner lining mammalian hair, which was observed from November 2015 through July 2016. The nest was built in a pendant flowerpot at a house located in the downtown of Quito. Two pale bluish eggs speckled with brown were incubated. I estimated a period of 11 days for nest building, 2 days for egg laying, 14 days for incubation, and 14 days for brooding.Keywords: breeding, eggs, incubation, nest, nestlings, Quito, Rufous-collared Sparrow.
NUEVO REGISTRO DE ANIDACIÓN Y DESCRIPCION DE NIDO DEL MOSQUERO REAL DEL PACÍFICO ONYCHORHYNCHUS OCCIDENTALIS (PASSERIFORMES: TYRANNIDAE) EN EL ORO, ECUADOR
Authors: Pezo Yaguana Karla Vanessa 
Published: June 2020

El Mosquero Real del Pacífico se encuentra distribuido en el Ecuador en los bosques húmedos y semideciduos del sur occidente de los Andes, estos bosques actualmente se encuentran bajo presión por actividades antrópicas, principalmente debido a la ampliación de la frontera agrícola, lo cual hace que esta especie esté considerada como vulnerable a la extinción a escala global y local. Existe además limitada información sobre su comportamiento, ecología y especialmente sobre su biología reproductiva, es por esto que en esta nota se detalla información sobre su etología reproductiva, se describe el cuidado parental y se da una descripción de su nido por primera vez en la provincia de El Oro. Esperando que esta nueva información contribuya al conocimiento de esta especie y pueda ser incorporada en futuros planes de conservación. New record of nesting and nest description of Pacific Royal Flycatcher Onychorhynchus occidentalis (Passeriformes: Tyrannidae) in El Oro, EcuadorThe Pacific royal flycatcher is distributed in Ecuador in the humid and semi-deciduous forests of the southwestern Andes, these forests are currently under pressure from anthropic activities, mainly the expansion of the agricultural frontier, which makes this species to be considered as vulnerable to extinction on a global and local scale. There is also limited information about its behavior, ecology and especially about its reproductive biology, in this note I give information about its reproductive ethology, describing parental care and gives a description of its nest for the first time in the province El Oro. I hope this new information will contribute to the knowledge of this species and can be incorporated into future conservation plans.
La construcción de los edificios escolares: confluencia de los discursos pedagógicos y políticos a fines del siglo XIX
Authors: Hernández Ortiz Francisco 
Published: June 2020

RESUMEN
Este trabajo da a conocer las condiciones en las que surgen los primeros edificios escolares a fines del siglo XIX en las ciudades de Buenos Aires, Argentina y San Luis Potosí, México respectivamente. La metodología, analítico- sintético, ayudó a la reconstrucción histórica complementada con técnicas del método comparativo, permitió identificar rasgos comunes y diferenciados en el origen de los primeros edificios escolares en las dos ciudades latinoamericanas. Los conceptos teóricos bajo los cuales se hace la argumentación son: pedagogía, educación moderna, higiene escolar, modernidad, patrimonio histórico educativo y Estado. El estudio muestra el paralelismo del surgimiento de los primeros edificios escolares, espacios para la educación escolarizada bajo la tutela del Estado, con una infraestructura específica, como resultado de los avances de la pedagogía, la medicina, la arquitectura e ingeniería, como evidencia de la modernidad de fines del siglo XIX en estas dos regiones del continente americano.
Palabras clave: Higiene. Modernización. Pedagogía. Educación. Espacio. Edificio escolar. Patrimonio histórico educativo.
DAMPAK EKONOMI DAN KEBERLANJUTAN PENERAPAN PENGELOLAAN KELAPA TERPADU DI KABUPATEN MINAHASA UTARA
Authors: T.P. HUTAPEA RONALD , T. TENDA ELSJE 
Published: June 2020

<p>ABSTRAK</p><p>Akselerasi adopsi teknologi pengelolaan kelapa terpadu merupakankegiatan yang dilakukan untuk mempercepat diseminasi teknologi danmengevaluasi model yang telah dikembangkan oleh Balitka di DesaKaleosan, Kabupaten Minahasa Utara pada tahun 2004-2006.Pengumpulan data menggunakan metode survei dan dilaksanakan padabulan November 2006. Data yang dikumpulkan meliputi karakteristikpetani, tingkat penerapan teknologi, serta usahatani. Penelitian inibertujuan untuk memperoleh informasi (1) tingkat adopsi dan difusiteknologi anjuran, (2) dampak teknologi terhadap pendapatan petani, dan(3) keberlanjutan organisasi kelompok tani. Hasil penelitian menunjukkanbahwa tingkat adopsi dan difusi teknologi pembibitan kelapa dan tanamansela jagung direspon cukup baik, dengan kisaran tingkat adopsi dan difusiteknologi sebesar 57,33-70,33. Kegiatan integrasi kelapa dengan ternakbabi serta pengolahan VCO tidak terjadi proses difusi, walaupun tingkatadopsi pada kelompok tani cukup tinggi dengan kisaran 60,00 – 85,33.Dampak ekonomi dari penerapan teknologi anjuran tanaman sela danpengaruhnya terhadap produktivitas kelapa menunjukkan dampak yangpositif, dengan nilai kelayakan finansial BCR dan MBCR &gt;1. Dampakkeberlanjutan organisasi kedua kelompok tani berada pada kelompokberkembang.</p><p>Kata kunci : Kelapa, sistem usahatani, adopsi teknologi, percepatan</p><p>ABSTRACT</p><p>Acceleration of management technology adoption ofintegrated coconut in North Minahasa regionIntegrated coconut management technology is a disseminationmodel to accelerate technology adoption in Kaleosan Village, NorthMinahasa in year 2004 – 2006. The research used survey method and wasconducted in November 2006. The data collected included farmers’characteristic, level of technology implementation, and farming systemanalysis. The purpose of this research was to gather information about (1)adoption and diffusion level of recommended technology, (2) impact oftechnology toward farmers’ income, (3) and the continuation of farmers’organization. The research result showed that the adoption stage ofcoconut seedling technology and corn intercropping was responded fairlywith the adoption stage and technologi diffusion of 57.33 – 70.33. Thediffusion process did not happen in the activity of coconut integration withpig cattle and VCO processing, eventhough the adoption stage of farmersgroup was relatively high, about 60.00 – 85.33. Economic impact ofrecommended intercropping technology application and the effect oncoconut productivity showed a positive result, with the BCR and MBCRvalues of &gt; 1. The continuity of both farmers groups has been still indeveloping level.</p><p>Key words : Coconut, farming system, technology adoption, integration</p>
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy
Authors: Feng Qingyuan , Bian Xuzhao , Liu Xuan , Wang Ying , Zhou Huiting , Ma Xiaojing , Quan Chunju , Yao Yi , Zheng Zhongliang 
Published: June 2020

Abstract
Background：Based on its low toxicity, arginine starvation therapy has the potential to cure malignant tumors that cannot be treated surgically. The Arginine deiminase (ADI) gene has been identified to be an ideal cancer-suppressor gene. ADI expressed in the cytosol displays higher oncolytic efficiency than ADI-PEG20 (Pegylated Arginine Deiminase by PEG 20,000). However, it is still unknown whether cytosolic ADI has the same mechanism of action as ADI-PEG20 or other underlying cellular mechanisms.Methods: The interactions of ADI with other protein factors were screened by yeast hybrids, and verified by co-immunoprecipitation and immunofluorescent staining. The effect of ADI inhibiting the ferritin light-chain domain (FTL) in mitochondrial damage was evaluated by site-directed mutation and flow cytometry. Control of the mitochondrial apoptosis pathway was analyzed by Western Blotting and real-time PCR experiments. The effect of p53 expression on cancer cells death was assessed by siTP53 transfection. Chromatin autophagy was explored by immunofluorescent staining and Western Blotting.Results: ADI expressed in the cytosol inhibited the activity of cytosolic ferritin by interacting with FTL. The inactive mutant of ADI still induced apoptosis in certain cell lines of ASS- through mitochondrial damage. Arginine starvation also generated an increase in the expression of p53 and p53AIP1, which aggravated the cellular mitochondrial damage. Chromatin autophagy appeared at a later stage of arginine starvation. DNA damage occurred along with the entire arginine starvation process. Histone 3 (H3) was found in autophagosomes, which implies that cancer cells attempted to utilize the arginine present in histones to survive during arginine starvation. Conclusions: Mitochondrial damage is the major mechanism of cell death induced by cytosolic ADI. The process of Chromatophagy does not only stimulate cancer cells to utilize histone arginine but also speeds up cancer cell death at a later stage of arginine starvation.
Measuring productivity of healthcare services under environmental constraints: Evidence from China
Authors: Yu Jinna , liu zhen , Zhang Tingting , Hatab Assem Abu , Lan Jing 
Published: June 2020

Abstract
Background: Despite the growing literature on the efficiency and productivity of the Chinese healthcare system, less attention has been given to examining the undesirable outputs linked to healthcare services, including environmental pollution. Taking the atmospheric environmental pollution resulting from the incineration of medical waste as an undesirable output of the healthcare system, this study analyzed the growth and decomposition of Total Factor Productivity (TFP) of healthcare services across 31 Chinese provinces during the period 2005-2016. Methods: The Meta-frontier undesirable super-efficiency slack-based measure (SBM) model and the Global Malmquist-Luenberger (GML) Index were employed to analyze the growth and decomposition of TFP using the Max DEA software. Results: The results revealed that the years 2009 and 2015 marked significant changes in TFP of healthcare services in Chinese provinces. During the study period, the rate of technological change (TC) slowly declined, whereas the rate of efficiency change (EC) steadily increased. With the national average being the benchmark, the results indicated that: the TFP of 17 provinces and cities exceeded the average, the EC changes of 16 provinces and cities exceeded the average, the TC changes of 9 provinces and cities exceeded the average, and the in the Technology Gap Ratio (TGR) changes of 13 provinces and cities were above the national average. Conclusions: (1) The TFP of the healthcare services across China continued to decline slowly during the study period. (2) The effect of technical catch-up in the eastern, central, and western regions of China was significant across the three regions, whereas the effect of technical innovation was negative. (3) The TFP varied considerably among the Chinese provinces. These findings suggest that, under existing environmental constraints, relevant government departments should improve technical innovation in the supply of healthcare services and medical waste treatment, increase technical efficiency in the factor of healthcare production, strengthen regional health planning, and balance the development of regional healthcare.
Single-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and the risk of pre- and postmenopausal breast cancer
Authors: Cao Shang , Zhu Zheng , Zhou Jinyi , Li Wei , Dong Yunqiu , Qian Yun , Wei Pingmin , Wu Ming 
Published: June 2020

Abstract
Background: One-carbon metabolism pathway could interfere with the carcinogenesis of breast cancer (BC). Dietary pattern plays an important role in one-carbon metabolism linking the combination of dietary micronutrients. Methods: We assessed associations between single-nucleotide polymorphisms (SNPs) of one-carbon metabolism, adherence to Mediterranean dietary pattern (MDP) and BC risk from a case-control study (818 cases, 935 controls) among Chinese female population. The genotyping of 10 SNPs in seven one-carbon metabolism-related genes (MTHFD1, MTRR, MAT2B, CDO1, FOLR1, UNG2, ADA) were performed. Dietary intake measurements were assessed by a validated food-frequency questionnaire. Gene-diet interactions were analyzed. Results: No evidence demonstrated SNPs of one-carbon metabolism or their haplotypes were associated with BC risk. High adherence to the Mediterranean dietary pattern decreased the risk of breast cancer among post- but not premenopausal women and the association was influenced by the SNPs genotype, with the increasing number of variant allele in MTHFD1 (rs11627387), MTHFD1 (rs2281603), MTRR (rs16879334), MTRR (rs2287780), MAT2B (rs4869087), FOLR1 (rs10501409), UNG2 (rs231622) and ADA (rs244072). The protective effect against BC risk from high adherence to the MDP was gradually weakened and disappeared. For MTHFD1 (rs8003567) and CDO1 (rs34869) genotypes, women with homozygous were less affected by adherence to the MDP than to women who with heterozygotes. No significant gene-diet interactions were observed.Conclusions: SNPs of one-carbon metabolism genes modify the effect of high adherence to MDP against BC risk in Chinese women, as potential effect modifiers. Genetic variants may influence the association between diet and BC risk.
The effect of total flavonoids from Saussurea involucrata on the secretion of pro-inflammatory mediators in lipopolysaccharide stimulated RAW264.7 macrophages
Authors: Yan Li-Shan , Wang Li , Cheng Brian Chi-Yan , Ding Yu , Kong Jing , Wang Qing Gao , Fu Xiu-Qiong , Zhang Shuo-Feng , Luo Gan , Zhang Yi 
Published: June 2020

Abstract
The authors have withdrawn this preprint due to author disagreement.
Impact of Covid-19 on General Surgical Practice in India
Authors: Nasta Amrit Manik , Goel Ramen , Manickavasagam Kanagavel , Sundaram Easwaramoorthy 
Published: June 2020

Abstract
Introduction: The Coronavirus disease—2019 (COVID‐19) pandemic is a global health crisis and surgeons are at increased occupational risk of contracting COVID‐19. The impact of the disease on prevalent general surgical practice is uncertain and continues to evolve.Aims/Objectives: To study the impact of COVID-19 on general surgical practice in India and the future implications of the pandemic.Methods: A survey questionnaire was designed and electronically circulated one month after India entered a national lockdown during covid-19 pandemic, among members of Indian Association of Gastro-intestinal Endo-surgeons (IAGES), a surgical association with nearly eight thousand members. Survey questions pertaining to pre-COVID era surgical practices, impact on current practice and financial implications were asked. Responses were collected and statistically analyzed.Results: 153 surgeons completed the survey, of which only 9.2% were females. 41% surgeons were more than 20 years into practice. 36.6% were into private practice at multiple hospitals (free-lancers). 41.8% had mainly laparoscopic practice with mean outpatient consultation of 26 patients/day and elective surgeries of 43 cases /month prior to lockdown. Post lock-down, daily outpatient consults reduced to 4 patients/day and 77% had not performed even a single elective procedure. 52% were taking hydroxychloroquine (HCQ) as chemoprophylaxis. 56.9% stated they are using personal protective equipment for all cases while 71.5% stated there are insufficient guidelines for future surgical practice in terms of safety. 52% surgeons stated a drop of more than 75% of their monthly income while 22% faced 50-75% reduction. 33% of respondents own a hospital and are expecting a monthly financial liability of 2.25 Million rupees (nearly 30,000 US dollars).Conclusion: COVID 19 has led to a drastic reduction in outpatient and elective surgical practices. There is a definite need for guidelines regarding safety for future surgical practices and solutions to overcome the financial liabilities in the near future.
A nomogram model assessing prognostic factors in patients with chemo/radiotherapy of small-cell lung cancer
Authors: Tan Shuzhen , Huang Yongmei , Kong Ying , Zhang Ming , Leng Shuilong , Zhu Xiao 
Published: June 2020

Abstract
Background: Small-cell lung cancer (SCLC) is difficult to cure. In this study, the SEER database was used to construct a nomogram model and explore the potential prognostic factors of SCLC patients who treated with chemo/radiotherapy. Methods: The data were sorted out and randomly divided into training cohort and verification cohort. Univariate and multivariate Cox regression were used in the training cohort to analyze the independent prognostic factors, then they be incorporated into the Nomogram model. Using the C-index, calibration algorithm and ROC in conjunction with the risk scores, the model was verified with the verification cohort. Finally, the overall survivals of those factors were evaluated in the total cases.Results: In the training cohort, we found that age, race, sex, total stage and extension were independent factors which were included in the nomogram model. C-index(s) that obtained from the training and verification cohorts showed that the model has predictive power. Moreover, the calibration curves and AUC results proved that the model is of great consistency not only in the training cohort but also in the verification cohort. Finally, significant differences in survival were observed among the above-mentioned factors and the overall survivals decreased over time.Conclusions: Age, race, sex, total stage and extension degree are independent factors for overall survival of patients. The nomogram model can better predict the 1-year, 3-year and 5-year survival probabilities, providing accurate reference for clinical individualized treatment.
Outcome and Predictive Factors in Rapid Progressive Cervical Spondylotic Myelopathy: A Retrospective Case-Control Study
Authors: Abuduaini Haimiti , Liu Hao , Wang Beiyu , Meng Yang , Yang Yi , Ding Chen , Wu Tingkui , Huang Chengyi 
Published: June 2020

Abstract
Background: To evaluate epidemiological, clinical and radiographic features in the development and prognosis of rapid progressive cervical spondylotic myelopathy (rp-CSM).Methods: A retrospective study of 175 patient records was performed between March 2011 and January 2017. Patients were divided into rp-CSM group and chronic CSM (c-CSM) group according to the deterioration time and severity of preoperative neurological dysfunction. After selection, 25 rp-CSM patients were matched to a control group of 75 patients with c-CSM. The clinical outcomes were assessed by the Modified Japanese Orthopaedic Association (mJOA) score at six different follow-up time points. The imaging parameters including Torg-Pavlov Ratio (TPR) on conventional lateral x-ray and magnetic resonance images (MRI), intervertebral disc level compression ratio and increased signal intensity (ISI) on T2W1 were analyzed between the two groups, and predictors for rapid neurological dysfunction in CSM patients were evaluated using multivariate analysis.Results: Twenty-five patients experienced rp-CSM (18 males; median age 59.04 ± 12.81 years) and were matched with Seventy-five control subjects that with CSM without rapid progression (54 males; median age 56.88 ± 12.31 years). The average time to develop severe neurological deterioration was 0.8 month in rp-CSM group and 24 month in c-CSM group (p=0.001), preoperative mJOA were 6 in rp-CSM patients and 12 in c-CSM patients (p=0.014) and rp-CSM patients demonstrated worse outcomes than the controls in one year after surgery (mJOA improvement rate 54.5% and 80%, p=0.021). There were no differences between the two groups except the history of diabetes and the long-term smoking in basic condition, radiographic measurements signified that TPR MRI, intervertebral disc level compression ratio and increased signal intensity (ISI) on T2W1 were inferior in patients with rp-CSM than patients with c-CSM. Regression analysis verified that the history of diabetes, TPR MRI < 0.4, compression ratio ≥50%, the sagittal diameter of ISI ≥50% of spinal canal diameter on T2W1 have significant correlations with the rapid progressive neurological dysfunction in patients with CSM. Conclusion: The prognosis of rapid progressive CSM is worse than that of common chronic CSM. The rapid neurological deterioration can be identified by TPR MRI (< 0.4), compression ratio (≥50%), sagittal diameter of ISI (≥50% of spinal canal diameter). Besides, a history of diabetes was also a negative factor for these patients.