bluuebunny/crossref_metadata_2025_split huggingface dataset:
Service quality factors: Web navigation on online transportation in Indonesia
Authors: Mulyana T , Susilawati W , Wufron W , Mardani N 
Published: December 2019

Abstract
The purpose of this research to analyse the service quality of online transportation an area in Indonesia, seen from consumer perceptions, and map service quality attributes based on consumer perceptions. The research method used in this research is Service Quality Analysis (SERVQUAL) and Importance Performance Analysis (IPA). The population in this research is online transportation consumers, who have used a go ride service at least 1 time. The sampling used in this research was sampling quota of 200 respondents. The results of this research indicate that overall there is a gap between performance values with consumer expectations of -0.5, so it can be assumed that the service quality of Gojek in the region according to consumer perceptions is quite good. Based on the results of the mapping it was found that the factor of ease of web navigation became one of the factors of the services quality of online transportation. So that these factors must be a concern of the company.
DOMI KALI: Elementary school multiplication learning media
Authors: Yuniasih N , Putri R E N , Nita C I R , Findawati Y 
Published: December 2019

Abstract
The purpose of this study is 1) to develop DOMI KALI media, 2) to describe the feasibility of the DOMI KALI media, 3) to describe the practicality of the DOMI KALI media. The method used is adapted from the ADDIE model with four stages, namely: analysis, design, development and implementation. The subjects of the trial were the third grade students of Sumbersari Elementary School 2. The instruments of data collection used validation sheets, questionnaires, unstructured interviews. The results showed that the DOMI KALI media is feasible to use. It obtained a percentage of 90.69% of the experts so that it was included in the feasible category. DOMI KALI is right to understand multiplication and more pleasant learning atmosphere. It is suggested to the teacher to use the DOMI KALI Media as a tool in learning activities so that the multiplication counting operation material is more fun.
Implementation of Multivariate Exponentially Weighted Mean Square (MEWMS) control chart for quality control of wing parts of Airbus aircraft at PT Dirgantara Indonesia
Authors: Enjang E , Nurdin F S , Setiawan W , Subekti E , Rahmawati D 
Published: December 2019

Abstract
Quality control must be carried out very tightly for the production of single wing multivariate dispersion aircraft manufacturing. This research was conducted at PT. Dirgantara Indonesia in producing components of Airbus aircraft wings centered in Germany and France. The method used includes three stages, namely determining the single observation MEWMS diagram, determining the algorithm for determining L, and implementing MEWMS. The data used are L simulation data for p = 2 and p = 3, ARL = 370, and various values, key characteristic data from 31 wing component components of the aircraft fly with. The results showed that the more variables, the L value as the determinant of the width of the MEWMS control limit was smaller, and the greater the value of ω, the value of L as the width of the MEWMS control border width is wider.
Experiences of analysis ToolPak in Matrix Algebra
Authors: Maryati I , Sumartini T S , Noordyana M A , Sofyan D , Madio S S 
Published: December 2019

Abstract
Analysis toolpak is very useful for a problem related with matrix material the purpose of this research article is to analyze the effectiveness of using the ToolPak analysis on matrix algebra. The method of this study is an experimental method with quasi-experimental design. The sample in this study took 27 students at the first years of the one at a private college in Indonesia. The results of processing data show that the value tcount equal to 9,207 and then the value (2-tailed) equal to 0,000 smaller than alpha 0.05 so that Ho is rejected. As the implication from this study the use of effective ToolPak analysis to improve students mathematical reasoning abilities in matrix algebraic material
The analysis of mathematics with ATLAS.ti
Authors: Afriansyah E A , Puspitasari N , Luritawaty I P , Mardiani D , Sundayana R 
Published: December 2019

Abstract
The teacher is one of the important factors in a good teaching and learning process. A teacher is required to have qualified cognitive and pedagogical abilities, so that he/she is creative in everything, including problem posing. Many studies discussed the problem of students’ ability but not many discussed the problem of teachers’ ability itself. This study used ATLAS.ti software as a tool for data analysis. ATLAS.ti software assisted researchers to manage all various data. The research was conducted on prospective teachers in one private institution. Observations and tests were conducted on 40 respondents, while only 6 respondents were involved at the time of the phase, namely interviews. Through ATLAS.ti software, the result showed that the problem posing skill of prospective teachers was still far from enough. What is needed is the right action to overcome the problem.
Cho—Maison magnetic monopole: BPS limit and lower mass bound
Authors: Beneš Petr , Blaschke Filip 
Published: December 2019

Abstract
We construct a class of effective extensions of the Standard Model that support finite-mass Cho–Maison magnetic monopole in the Bogomol’nyi–Prasad–Sommerfield (BPS) limit. We present an example of exact analytic monopole solution and derive a universal lower mass bound M ⩾ 2πυ/g ≈ 2.37 TeV of the Cho–Maison magnetic monopole.
Operator-algebraic construction of the deformed Sine-Gordon model
Authors: Cadamuro Daniela 
Published: December 2019

Abstract
We consider the construction of integrable quantum field theories in the operator-algebraic approach, which is based on quantum fields localized in infinitely extended wedge regions. This approach has been successful for the construction of a class of models with scalar S-matrices and without bound states. In extension of these results, we apply similar methods to S-matrices with poles in the physical strip (“bound states”). Specifically, we consider a deformed version of the Sine-Gordon model, containing only breathers. We exhibit wedge-local fields in this model, which differ from those in non-bound state models by an additive term, the so called “bound state operator”.
On calculation of quadrupole operator in orthogonal Bargmann-Moshinsky basis of SU(3) group
Authors: Deveikis A. , Gusev A.A. , Vinitsky S.I. , Pe¸drak A. , Burdík Č , Góźdź A. , Krassovitskiy P.M. 
Published: December 2019

Abstract
Construction of orthonormal states of the noncanonical Bargmann-Moshinsky basis in a nonmultiplicity-free case is presented. It is implemented by means of the both Gram-Schmidt procedure and solving eigenvalue problem of the Hermitian labeling operator of an envelope algebra of the SU(3) group. Calculations of the quadrupole and Bargmann-Moshinsky operators and its matrix elements needed for construction of the nuclear models are tested. Comparison of results in the integer and floating point calculations with help of the proposed procedures implemented in Wolfram Mathematica is given.
Supersymmetric Calogero and Calogero-Sutherland models from gauging
Authors: Ivanov Evgeny 
Published: December 2019

Abstract
We describe how the new kinds of N = 2 and N = 4 supersymmetric extensions of the rational and hyperbolic Calogero models can be derived by gauging U(n) symmetry of the appropriate superfield matrix models. These systems feature non-standard numbers N n
2 of physical fermionic variables as compared with N n in the standard case. An essential ingredient of N = 4 models is the necessary presence of semi-dynamical spin variables described by d = 1 Wess-Zumino terms. The bosonic cores of N = 4 models are U(2) spin Calogero and Calogero-Sutherland models. In the hyperbolic case two non-equivalent N = 4 extensions exist, with and without the interacting center-of-mass coordinate in the bosonic sector. The talk is based on joint works with Sergey Fedoruk and Olaf Lechtenfeld.
Towards a Z3-graded approach to quarks’ symmetries
Authors: Kerner Richard , Lukierski Jerzy 
Published: December 2019

Abstract
Colour SU(3) group is an exact symmetry of Quantum Chromodynamics, which describes strong interactions between quarks and gluons. Supplemented by two internal symmetries, SU(2) and U(1), it serves as the internal symmetry of the Standard Model, describing as well the electroweak interactions of quarks and leptons. The colour SU(3) symmetry is exact, while two other symmetries are broken by means of the Higgs-Kibble mechanism. The three colours and fractional quarks charges with values 1/3 and 2/3 suggest that the cyclic group Z
3 may play a crucial role in quark field dynamics.
In this paper we consequently apply the Z
3 symmetry to field multiplets describing colour quark fields. Generalized Dirac equation for coloured 12-component spinors is introduced and its properties are discussed. Imposing Z
3-graded Lorentz and Poincaré covariance leads to enlargement of quark fields multiplets and incorporates additional Z
2
× Z
3 symmetry which leads to the appearance of three generations (families) of distinct quark doublets.
Features of the twistor formulation of the massless superparticle on AdS5 × S5 superbackground
Authors: Uvarov D V 
Published: December 2019

Abstract
We study supertwistor formulations of the D = 10 massless superparticle model on AdS
5
× S
5 superbackground of IIB supergravity. Product structure of the background suggests using Spin(1, 4) variables to express momentum components tangent to AdS
5 and Spin(5) variables to express momentum components tangent to S
5 that yields eight-supertwistor formulation of the superparticle’s Lagrangian. We find incidence relations connecting supertwistor components with the AdS
5
× S
5 superspace coordinates and the set of the constraints that supertwistors satisfy. Solving the constraints for the Spin(1, 4) and Spin(5) variables it is possible to reduce eight-supertwistor formulation to the four-supertwistor one. Respective supertwistors agree with those introduced previously in other models. The advantage of the four-supertwistor formulation is the presence only of the first-class constraints that facilitates analysis of the superparticle model.
On modeling neutrinos oscillations by geometry methods in the frames of the theory for a fermion with three mass parameters
Authors: Voynova Ya.A. , Ovsiyuk E A , Kisel V V , Pletyukhov V A , Gilewsky V V , Red’kov V M 
Published: December 2019

Abstract
Starting from the general Gel’fand-Yaglom approach, we develop the theory of a new wave equation for a spin 1/2 fermion, which is characterized by three mass parameters. On the base of a 20-component wave function, three auxiliary bispinors are introduced, in absence of external fields these bispinors obey three separate Dirac-like equations with different masses. In presence of external electromagnetic fields or gravitational non-Euclidean background with a non-vanishing Ricci scalar curvature, the main equation is not split into separated three equations, instead a quite definite mixing of three Dirac-like equations arises. It is shown that for neutral Majorana particle, a generalized equation with three mass parameters exists as well. Such a generalized Majorana equation is not split into three separated equations in the curved space-time background, if the Ricci scalar of that space-time does not vanish. We have studied in detail the Majorana case, assuming approximation when an external cosmological background is taken into account by a constant Ricci parameter, R = const, and the Cartesian coordinates are used. With the help of a special linear transformation, the system of three linked Majorana equations transforms into three separate ones, with modified mass parameters, the last are solvable in the usual way. The spectrum of arising mass parameters is studied analytically and numerically.
A Quantum Electromagnetic Theory of the Pions, Muons and Their Emitting Particles (I)
Authors: Zheng-Johansson J X 
Published: December 2019

Abstract
In direct accordance to the overall relevant experimental demonstrations, we represent the charged pion π- as a heavy electron h
- in precessional-orbital (P-O) motion at essentially the light speed c about

υ
¯

e

-orbit of a normal at quantised angle π − θ1/2 = − arccos

(

1
/

3

)

to the z axis. h
- is the level N = 1 oscillation of charge −e and its electromagnetic radiation originally generated in the weak potential field of another particle. The P-O kinetic energy current and two additional opposite ones created upon π- decay represent confined neutrinos

υ
¯

e

,

υ
¯

μ

,

υ
μ

. The muon µ- is a xy-projected h
- in two superposing P-O motions along

υ
¯

e
−

,

υ
μ

- orbits of normals at angles π − θ1/2, θ1/2 to z. The µ- (rest) mass is a geometric projection of the reduced π- mass,

M
μ

=
(

M
π

−

M

υ
μ

)

cos

θ

1
/
2

=
105.86
MeV

. The µ- mass is fundamentally predetermined by the mixed two states ml
= −1, +1 of level n = 2 of a double heavy positronium in the CM frame produced in a relativistic e
-, e
+ collision, and is ab initio predicted to be

M

μ
−

=

(

3
4

2
α

+
1

)

M
e

=
105.549
MeV

, where

α
=

e
2

/

4
π

∈
0

ℏ
c

. The un-projected n = 2 level gives the bound π- mass containing a friction term

O
η

,

M
π

+

O
η

=

(

2
α

+
1

)

M
e

=
140.525
MeV

. Their antiparticles π+, µ+ and the tauons τ∓ can be similarly represented. The remaining unstable elementary particles can be constructed as composites of two or more single charged ones in certain spatial quantised P-O motions.
3O A pre-existing inflammatory immune microenvironment predicts the clinical and immunological response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 peptide vaccination
Authors: Abdulrahman Z , de Miranda N F C C , van Poelgeest M I E , van der Burg S H 
Published: December 2019

Abstract

Background
Vulvar High-grade Squamous Intraepithelial Lesion (vHSIL) is predominantly induced by high-risk Human Papilloma Virus type 16 (HPV16). In two independent trials, therapeutic vaccination against the oncoproteins of HPV16 with synthetic long peptides (SLP) resulted in vHSIL regression in about half of the patients after 12 months. Several studies have shown that the immune microenvironment influences therapy outcome. Therefore, a thorough investigation of the vHSIL immune microenvironment before and after SLP vaccination was performed, and its impact on clinical response was studied.

Methods
Two novel multiplex immunofluorescence panels were designed for formalin-fixed paraffin-embedded tissue, one for T cells (CD3, CD8, FoxP3, Tim3, Tbet, PD-1, DAPI) and one for myeloid cells (CD14, CD33, CD68, CD163, CD11c, PD-L1, DAPI). Pre- and 3 months post-vaccination biopsies of 29 patients and 27 healthy vulva excisions were stained, scanned with the Vectra multispectral imaging system, and automatically phenotyped and counted with inForm advanced image analysis software.

Results
A pre-existing pro-inflammatory TME, marked by high numbers of CD4 and CD8 T cells expressing Tbet and/or PD-1 as well as CD14+ inflammatory macrophages, is a strong predictor for good clinical response. A clear stepwise increase in pre-vaccination infiltrating Tbet+, CD4+, CD8+ T cells and CD14+ macrophages, and decrease in Foxp3+ Tregs was observed as response increased from non to partial to complete response. Moreover, the pre-vaccination immune microenvironment of complete responders resembled healthy vulva. Vaccination further increased infiltrating CD4+ and Tbet+ T cells and CD14+ macrophages and decreased FoxP3+ Tregs in the complete and partial responders, but not in the non responders.

Conclusion
Clinical responsiveness to therapeutic HPV16 SLP vaccination requires a pre-existing inflamed type 1 immune contexture in vHSIL. Hence, only patients with an inflamed TME should be selected for monotherapy by therapeutic vaccination, since this strategy is incapable of creating an inflamed TME in patients where this is absent.

Legal entity responsible for the study
The authors.

Funding
Leiden University Medical Center.

Disclosure
S.H. van der Burg: Advisory / Consultancy: ISA Pharmaceuticals. All other authors have declared no conflicts of interest.
Cleavage of SPACA1 regulates assembly of sperm–egg membrane fusion machinery in mature spermatozoa†
Authors: Yamatoya Kenji , Kousaka Marika , Ito Chizuru , Nakata Kazuya , Hatano Masahiko , Araki Yoshihiko , Toshimori Kiyotaka 
Published: December 2019

AbstractThe acrosome reaction is a multi-step event essential for physiological fertilization. During the acrosome reaction, gamete fusion-related factor IZUMO1 translocates from the anterior acrosome to the equatorial segment and assembles the gamete fusion machinery. The morphological changes in the acrosome reaction process have been well studied, but little is known about the molecular mechanisms of acrosome reorganization essential for physiological gamete membrane fusion. To elucidate the molecular mechanisms of IZUMO1 translocation, the steps of the acrosome reaction during that process must be clarified. In this study, we established a method to detect the early steps of the acrosome reaction and subdivided the process into seven populations through the use of two epitope-defined antibodies, anti-IZUMO1 and anti-SPACA1, a fertilization-inhibiting antibody. We found that part of the SPACA1 C-terminus in the periacrosomal space was cleaved and had begun to disappear when the vesiculation of the anterior acrosome occurred. The IZUMO1 epitope externalized from the acrosomal lumen before acrosomal vesiculation and phosphorylation of IZUMO1 occurred during the translocation to the equatorial segment. IZUMO1 circumvented the area of the equatorial segment where the SPACA1C-terminus was still localized. We therefore propose an IZUMO1 translocation model and involvement of SPACA1.
Cyclophosphamide has Long-Term Effects on Proliferation in Olfactory Epithelia
Authors: Awadallah Nora , Proctor Kara , Joseph Kyle B , Delay Eugene R , Delay Rona J 
Published: December 2019

AbstractChemotherapy patients often experience chemosensory changes during and after drug therapy. The chemotherapy drug, cyclophosphamide (CYP), has known cytotoxic effects on sensory and proliferating cells of the taste system. Like the taste system, cells in the olfactory epithelia undergo continuous renewal. Therefore, we asked if a single injection of 75 mg/kg CYP would affect cell proliferation in the anterior dorsomedial region of the main olfactory epithelium (MOE) and the vomeronasal organ (VNO) from 0 to 125 days after injection. Both epithelia showed a decrease in Ki67-labeled cells compared to controls at day 1 and no Ki67+ cells at day 2 postinjection. In the sensory layer of the MOE, cell proliferation began to recover 4 days after CYP injection and by 6 days, the rate of proliferation was significantly greater than controls. Ki67+ cells peaked 30 days postinjection, then declined to control levels at day 45. Similar temporal sequences of initial CYP-induced suppression of cell proliferation followed by elevated rates peaking 30–45 days postinjection were seen in the sustentacular layer of the MOE and all 3 areas (sensory, sustentacular, marginal) of the VNO. CYP affected proliferation in the sensory layer of the MOE more than the sustentacular layer and all 3 areas of the VNO. These findings suggest that chemotherapy involving CYP is capable of affecting cell renewal of the olfactory system and likely contributes to clinical loss of function during and after chemotherapy.
Crustal anisotropy beneath northeastern Tibetan Plateau from the harmonic decomposition of receiver functions
Authors: Xie Zhenxin , Levin Vadim , Wu Qingju 
Published: December 2019

SUMMARY
A uniformly spaced linear transect through the northeastern Tibetan Plateau was constructed using 54 stations from ChinaArray Phase II. We used a set of colocated earthquakes to form receiver function beams that were then used to construct a 2-D image of main converting boundaries in our region and to investigate lateral changes in main impedance contrasts along the transect. The image revealed obvious mid-crustal low-velocity zones beneath the Qilian Orogen and the Alxa Block. We developed a new procedure that uses harmonically decomposed receiver functions to characterize seismic anisotropy, and that can determine both the orientations of symmetry axes and their type (fast or slow). We tested our technique on a number of synthetic models, and subsequently applied it to the data from the transect. We found that: (1) within the upper crust the orientations of slow symmetry axes are nearly orthogonal to the strike directions of faults, and thus anisotropy is likely caused by the shape preferred orientation of fluid-saturated cracks or fractures and (2) together with the low-velocity zones revealed from receiver functions stacks, anisotropic layers in the middle-to-lower crust could be explained by the crustal channel flow that was proposed for this region by previous studies. The shear within the boundary layers of crustal flow forms anisotropy with symmetry axes parallel to the flow direction.
Application of a gut-immune co-culture system for the study of N-glycan-dependent host–pathogen interactions of Campylobacter jejuni
Authors: Zamora Cristina Y , Ward Elizabeth M , Kester Jemila C , Chen Wen Li Kelly , Velazquez Jason G , Griffith Linda G , Imperiali Barbara 
Published: December 2019

Abstract
An in vitro gut-immune co-culture model with apical and basal accessibility, designed to more closely resemble a human intestinal microenvironment, was employed to study the role of the N-linked protein glycosylation pathway in Campylobacter jejuni pathogenicity. The gut-immune co-culture (GIC) was developed to model important aspects of the human small intestine by the inclusion of mucin-producing goblet cells, human enterocytes and dendritic cells, bringing together a mucus-containing epithelial monolayer with elements of the innate immune system. The utility of the system was demonstrated by characterizing host–pathogen interactions facilitated by N-linked glycosylation, such as host epithelial barrier functions, bacterial invasion and immunogenicity. Changes in human intestinal barrier functions in the presence of 11168 C. jejuni (wildtype) strains were quantified using GICs. The glycosylation-impaired strain 11168 ΔpglE was 100-fold less capable of adhering to and invading this intestinal model in cell infectivity assays. Quantification of inflammatory signaling revealed that 11168ΔpglE differentially modulated inflammatory responses in different intestinal microenvironments, suppressive in some but activating in others. Virulence-associated outer membrane vesicles produced by wildtype and 11168ΔpglE C. jejuni were shown to have differential composition and function, with both leading to immune system activation when provided to the gut-immune co-culture model. This analysis of aspects of C. jejuni infectivity in the presence and absence of its N-linked glycome is enabled by application of the gut-immune model, and we anticipate that this system will be applicable to further studies of C. jejuni and other enteropathogens of interest.