bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data science: developing theoretical contributions in information systems via text analytics
Authors: Rizk Aya , Elragal Ahmed 
Published: January 2020

AbstractScholars have been increasingly calling for innovative research in the organizational sciences in general, and the information systems (IS) field in specific, one that breaks from the dominance of gap-spotting and specific methodical confinements. Hence, pushing the boundaries of information systems is needed, and one way to do so is by relying more on data and less on a priori theory. Data, being considered one of the most important resources in research, and society at large, requires the application of scientific methods to extract valuable knowledge towards theoretical development. However, the nature of knowledge varies from a scientific discipline to another, and the views on data science (DS) studies are substantially diverse. These views vary from being seen as a new scientific (fourth) paradigm, to an extension of existing paradigms with new tools and methods, to a phenomenon or object of study. In this paper, we review these perspectives and expand on the view of data science as a methodology for scientific inquiry. Motivated by the IS discipline’s history and accumulated knowledge in using DS methods for understanding organizational and societal phenomena, IS theory and theoretical contributions are given particular attention as the key outcome of adopting such methodology. Exemplar studies are analyzed to show how rigor can be achieved, and an illustrative example using text analytics to study digital innovation is provided to guide researchers.
Sedimentation process of ashfall during a Vulcanian eruption as revealed by high-temporal-resolution grain size analysis and high-speed camera imaging
Authors: Miwa T. , Iriyama Y. , Nagai M. , Nanayama F. 
Published: January 2020

AbstractWe here examined the sedimentation process of falling ash particles during a short-lived Vulcanian eruption at Sakurajima volcano, Japan, using high-speed camera imaging of airborne ash particles, as well as grain size analyses of ash samples collected at high temporal resolution. Ashfalls from a sequence of two Vulcanian eruptions at 10:44 and 11:26 JST (Japan Standard Time) on 26 March 2016 were investigated. The field site for imaging and sampling was located approximately 3.5 km from the vent. The ash particles collected exhibit bimodal grain size distributions (GSDs). The median particle size of the main subpopulation decreased throughout the ashfall owing to size-dependent segregation of ash particles from a single source released from a constant height. The volume fraction of the subordinate subpopulation is interpreted to represent a component of ash aggregates and shows an increase in its volume fraction after the eruption onset. High-speed camera imaging reveals that the mean particle density decreased over time as the ashfall continued. These data suggest an increasing contribution of low-density aggregates during the course of the ashfall. The temporal changes in the density of airborne ash particles and in the GSD of ash samples demonstrate that the sedimentation process during a Vulcanian eruption at Sakurajima volcano is characterized by sedimentation of ash particles from transient eruption plumes at constant height, in which ash aggregation increases over time. Moreover, time series analysis of the ash falling rate shows that secondary thickening occurred during these Vulcanian eruptions and that this can be triggered by the settling of ash aggregates.
Disentangling the genetic bases of Saccharomyces cerevisiae nitrogen consumption and adaptation to low nitrogen environments in wine fermentation
Authors: Kessi-Pérez Eduardo I. , Molinet Jennifer , Martínez Claudio 
Published: January 2020

AbstractThe budding yeast Saccharomyces cerevisiae has been considered for more than 20 years as a premier model organism for biological sciences, also being the main microorganism used in wide industrial applications, like alcoholic fermentation in the winemaking process. Grape juice is a challenging environment for S. cerevisiae, with nitrogen deficiencies impairing fermentation rate and yeast biomass production, causing stuck or sluggish fermentations, thus generating sizeable economic losses for wine industry. In the present review, we summarize some recent efforts in the search of causative genes that account for yeast adaptation to low nitrogen environments, specially focused in wine fermentation conditions. We start presenting a brief perspective of yeast nitrogen utilization under wine fermentative conditions, highlighting yeast preference for some nitrogen sources above others. Then, we give an outlook of S. cerevisiae genetic diversity studies, paying special attention to efforts in genome sequencing for population structure determination and presenting QTL mapping as a powerful tool for phenotype–genotype correlations. Finally, we do a recapitulation of S. cerevisiae natural diversity related to low nitrogen adaptation, specially showing how different studies have left in evidence the central role of the TORC1 signalling pathway in nitrogen utilization and positioned wild S. cerevisiae strains as a reservoir of beneficial alleles with potential industrial applications (e.g. improvement of industrial yeasts for wine production). More studies focused in disentangling the genetic bases of S. cerevisiae adaptation in wine fermentation will be key to determine the domestication effects over low nitrogen adaptation, as well as to definitely proof that wild S. cerevisiae strains have potential genetic determinants for better adaptation to low nitrogen conditions.
Assessment of drivers and dynamics of gully erosion in case of Tabota Koromo and Koromo Danshe watersheds, South Central Ethiopia
Authors: Hassen Getahun , Bantider Amare 
Published: January 2020

AbstractGlobally erosion has been considered as an environmental and agricultural problem since the first agricultural revolution. In Ethiopia gully erosion has been recorded as a very serious and common socio-economic and environmental problem of several watersheds. Therefore, the objective of this research was to assess the drivers, dynamics and impacts of gully erosion in case of Tabota Koromo and Koromo Danshe watersheds, South-Central Ethiopia. The intended objectives were achieved by triangulating the image analysis with the data obtained from GPS, group discussion, interview, house hold survey, field observation and field measurement. The result of the study indicated that gully erosion was initiated in the steep slope following the 1970s and 1980s land cover change and other anthropogenic factors. In addition, the soil properties and steep slope (gravity) of the land have contributed in exacerbating the problems. Gully erosion caused physical, social and economic impacts in the area. According to the participants on group discussion and interview, the socio-economic impacts of gully erosion were loss of life for a 12 year boy, injuries of five live stocks, and decline of yields throughout the year. Result from field measurement and observation depicted that loss of soil (1,080,782.6m3) and loss of biodiversity are the major physical impacts of gully erosion. Yet there are promising conditions to rehabilitate the gullied area for sustainable ecosystem services in the watersheds. These promising conditions are the availability of high labour forces, access of transportation, civic societies working on natural resource conservation and the green economy development policy of the country. Therefore, concerned government bodies and the local communities at different level need to set plan and work for implementation in a way to use the existing opportunities.
Performance of the counter-torque technique in the explantation of nonmobile dental implants
Authors: Anitua Eduardo , Fernandez-de-Retana Sofia , Alkhraisat Mohammad H. 
Published: January 2020

Abstract
Background
The application of the counter-torque technique has been proposed as a conservative and atraumatic alternative for the explantation of nonmobile dental implants. The objective of this report is to assess the performance of this technique in a large number of patients.

Results
Three hundred and fifty-five patients were treated for the explantation of 749 nonmobile dental implants. The explantations were performed by the application of counter-torque to break the bone-implant interface. Successful implant explantation was achieved in 98.4% of the implants. The frequency of complications was 1.3%, most commonly related to the appearance of fissure lines at the implant neck.

Conclusions
The counter-torque technique has a high success rate but is not exempt from complications, although at a very low rate.
Patient-reported outcome measures in the interaction between patient and clinician – a multi-perspective qualitative study
Authors: Mejdahl Caroline Trillingsgaard , Schougaard Liv Marit Valen , Hjollund Niels Henrik , Riiskjær Erik , Lomborg Kirsten 
Published: January 2020

Abstract
Background
This article addresses patient-reported outcome (PRO)-based follow-up used as a substitute for regularly scheduled follow-ups. In PRO-based follow-up, patients’ PRO data filled in by the patients at home are used by clinicians as a decision aid to identify those who need clinical attention based on an automated PRO algorithm, clinical attention being either a phone call or a physical consultation. A physical consultation in the outpatient clinic prompted by the patient’s PRO is termed a “PRO consultation.”
In this multi-perspective qualitative study, we explored the influence of patients’ self-reported data on patient-clinician interaction during PRO consultations in epilepsy outpatient clinics. Interpretive description was the methodological approach, applying data from participant observations, informal interviews with clinicians, and semi-structured interviews with clinicians and patients.

Results
We found that application and deliberate use of patients’ PRO measures can affect patient-clinician interaction, promoting patient involvement in terms of improved communication and increased patient activation. These findings reflect the general patterns that have been reported in the literature. In addition, we found that PRO measures also may induce unmet expectations among some patients that can have a negative effect on patients’ experiences of the interaction and their follow-up experience in general. We extracted two thematic patterns that represent PRO measures’ potential for patient involvement in the patient-clinician interaction. The first pattern represents enablers, and the second pattern represents barriers for PRO measures to affect patient involvement.

Conclusions
Applying PRO measures in clinical practice does not automatically enhance the patient-clinician interaction. To strengthen the benefits of PRO measures, the following supplementary clinical initiatives are suggested: summarizing and reporting the PRO measures back to the patient, considering carefully which PRO measures to include, training clinicians and assuring that the patients’ introduction to PRO-based follow-up clarifies expectations.
Synthesis of silver nanoparticles using marine macroalgae Padina sp. and its antibacterial activity towards pathogenic bacteria
Authors: Bhuyar Prakash , Rahim Mohd Hasbi Ab. , Sundararaju Sathyavathi , Ramaraj Rameshprabu , Maniam Gaanty Pragas , Govindan Natanamurugaraj 
Published: January 2020

AbstractBackgroundMarine algae used as a food source for ocean life and range in color from red to green to brown grow along rocky shorelines around the world. The synthesis of silver nanoparticles by marine algaPadinasp. and its characterization were fulfilled by using UV-visible spectrophotometer, Fourier transform infrared spectroscopy, scanning electron microscopy and field emission scanning electron microscopy, and energy-dispersive X-ray spectroscopy.ResultsUV-visible absorption spectrum revealed that the formation of Ag nanoparticles was increased by the addition of marine algae and the spectral peak observed between a wavelength of ~ 420 nm and 445 nm. In addition, SEM and FESEM images examined the surface morphology and the size of the synthesized NPs was relatively uniform in size ~ 25–60 nm. Energy-dispersive X-ray spectroscopy analysis confirmed the purity of Ag NPs with atomic percentage of 48.34% Ag. The synthesized Ag NPs showed highly potent antibacterial activity. TheStaphylococcus aureusandPseudomonas aeruginosawere found to be more susceptible to silver nanoparticles by forming 15.17 ± 0.58 mm and 13.33 ± 0.76 mm of diameter of the inhibition zone, respectively.ConclusionsThe study suggested that marine algaPadinasp. could be an alternative source for the production of Ag nanoparticles and are efficient antimicrobial compounds against both gram-negative and gram-positive bacteria which can be a promising material against infectious bacteria.
Cardiac structure and function in schizophrenia: cardiac magnetic resonance imaging study
Authors: Osimo Emanuele F. , Brugger Stefan P. , de Marvao Antonio , Pillinger Toby , Whitehurst Thomas , Statton Ben , Quinlan Marina , Berry Alaine , Cook Stuart A. , O'Regan Declan P. , Howes Oliver D. 
Published: January 2020

BackgroundHeart disease is the leading cause of death in schizophrenia. However, there has been little research directly examining cardiac function in schizophrenia.AimsTo investigate cardiac structure and function in individuals with schizophrenia using cardiac magnetic resonance imaging (CMR) after excluding medical and metabolic comorbidity.MethodIn total, 80 participants underwent CMR to determine biventricular volumes and function and measures of blood pressure, physical activity and glycated haemoglobin levels. Individuals with schizophrenia (‘patients’) and controls were matched for age, gender, ethnicity and body surface area.ResultsPatients had significantly smaller indexed left ventricular (LV) end-diastolic volume (effect size d = −0.82, P = 0.001), LV end-systolic volume (d = −0.58, P = 0.02), LV stroke volume (d = −0.85, P = 0.001), right ventricular (RV) end-diastolic volume (d = −0.79, P = 0.002), RV end-systolic volume (d = −0.58, P = 0.02), and RV stroke volume (d = −0.87, P = 0.001) but unaltered ejection fractions relative to controls. LV concentricity (d = 0.73, P = 0.003) and septal thickness (d = 1.13, P < 0.001) were significantly larger in the patients. Mean concentricity in patients was above the reference range. The findings were largely unchanged after adjusting for smoking and/or exercise levels and were independent of medication dose and duration.ConclusionsIndividuals with schizophrenia show evidence of concentric cardiac remodelling compared with healthy controls of a similar age, gender, ethnicity, body surface area and blood pressure, and independent of smoking and activity levels. This could be contributing to the excess cardiovascular mortality observed in schizophrenia. Future studies should investigate the contribution of antipsychotic medication to these changes.
Prognostic Significance of Patient-Reported Outcomes in Cancer
Authors: Kerrigan Kathleen , Patel Shiven B. , Haaland Benjamin , Ose Dominik , Weinberg Chalmers Anna , Haydell Tyler , Meropol Neal J. , Akerley Wallace 
Published: January 2020

PURPOSE: Performance status (PS), an established prognostic surrogate of cancer survival, is a physician-synthesized metric of patient symptoms and mobility that is prone to bias and subjectivity. The National Cancer Institute (NCI) Patient-Reported Outcomes Measurement Information System–Cancer (PROMIS-Ca) Bank, a patient-centric patient-reported outcome (PRO) evaluation of physical function (PF), fatigue, depression, anxiety, and pain, shares subject matter with PS and, therefore, may also be prognostic while eliminating physician interpretation. METHODS: Patients at Huntsman Cancer Institute were assessed using the NCI PROMIS-Ca Bank. Using tablets at routine office visits, PF, fatigue, depression, anxiety, and pain scores were collected from patients with advanced melanoma, non–small-cell lung cancer, colorectal cancer, and breast cancer. A PRO score collected at a single time point within 6 months of metastatic diagnosis for each patient was merged with curated clinical outcome data. The association of PROs, overall survival (OS), and hospitalization-free survival (HFS) were assessed in multivariable analysis that included sex and cancer type. RESULTS: Two hundred eighty-two complete sets of patient data were available for analysis. All 5 PRO domains were strongly prognostic of OS and HFS. While the PRO domains were interrelated with moderate to strong correlations (0.40-0.79), multivariable regression suggested that PF was most strongly associated with the clinical outcomes of OS ( P < .001) and HFS ( P < .001). CONCLUSION: NCI PROMIS-Ca PROs may be prognostic of both cancer survival and likelihood of hospitalization. Future prospective studies are needed for all major prognostic factors to fully understand the independent prognostic value of PROs.
Bariatric Surgery vs Lifestyle Intervention for Diabetes Treatment: 5-Year Outcomes From a Randomized Trial
Authors: Courcoulas Anita P , Gallagher James W , Neiberg Rebecca H , Eagleton Emily B , DeLany James P , Lang Wei , Punchai Suriya , Gourash William , Jakicic John M 
Published: January 2020

Abstract

Context
Questions remain about bariatric surgery for type 2 diabetes mellitus (T2DM) treatment.

Objective
Compare the remission of T2DM following surgical or nonsurgical treatments.

Design, setting, and participants
Randomized controlled trial at the University of Pittsburgh, in the United States. Five-year follow-up from February 2015 until June 2016.

Interventions
61 participants with obesity and T2DM who were initially randomized to either bariatric surgical treatments (Roux-en-Y gastric bypass [RYGB] or laparoscopic adjustable gastric banding [LAGB]) or an intensive lifestyle weight loss intervention (LWLI) program for 1 year. Lower level lifestyle weight loss interventions (LLLIs) were then delivered for 4 years.

Main Outcomes and Measures
Diabetes remission assessed at 5 years.

Results
The mean age of the patients was 47 ± 6.6 years, 82% were women, and 21% African American. Mean hemoglobin A1c level 7.8% ± 1.9%, body mass index (BMI) 35.7 ± 3.1 kg/m2, and 26 participants (43%) had BMI &lt; 35 kg/m2. Partial or complete T2DM remission was achieved by 30% (n = 6) of RYGB, 19% (n = 4) of LAGB, and no LWLI participants (P = .0208). At 5 years those in the RYGB group had the largest percentage of individuals (56%) not requiring any medications for T2DM compared with those in the LAGB (45%) and LWLI (0%) groups (P = .0065). Mean reductions in percent body weight at 5 years was the greatest after RYGB 25.2% ± 2.1%, followed by LAGB 12.7% ± 2.0% and lifestyle treatment 5.1% ± 2.5% (all pairwise P &lt; .01).

Conclusions
Surgical treatments are more effective than lifestyle intervention alone for T2DM treatment.
Polycystic Ovary Syndrome Signs and Metabolic Syndrome in Premenopausal Hispanic/Latina Women: the HCHS/SOL Study
Authors: Meyer Michelle L , Sotres-Alvarez Daniela , Steiner Anne Z , Cousins Larry , Talavera Gregory A , Cai Jianwen , Daviglus Martha L , Loehr Laura R 
Published: January 2020

Abstract

Context
Polycystic ovary syndrome (PCOS), a condition of androgen excess in women, is associated with cardiometabolic risk factors; however, this association is not fully characterized in a population-based sample of premenopausal women and high-risk groups such as Hispanics/Latinas.

Objective
We examined the association of PCOS signs and metabolic syndrome (MetS) in premenopausal Hispanic/Latina women.

Methods
This cross-sectional analysis includes 1427 women age 24 to 44 years from the Hispanic Community Health Study/Study of Latinos. PCOS signs included menstrual cycle greater than 35 days or irregular, self-reported PCOS, and oral contraceptive use to regulate periods or acne, and a composite of 1 or more PCOS signs. We calculated odds ratios (OR) and 95% CI for MetS, accounting for sociodemographic factors and the complex survey design; an additional model included body mass index (BMI).

Results
The mean age was 34 years and 30% reported any PCOS sign. The odds of MetS were higher in women reporting cycles greater than 35 days or irregular (OR 1.63; CI: 1.07-2.49) vs cycles 24 to 35 days, self-reported PCOS (OR 2.49; CI: 1.38-4.50) vs no PCOS, and any PCOS sign (OR 1.58; CI: 1.10-2.26) vs none. We found no association between OC use to regulate periods or acne and MetS (OR 1.1; CI: 0.6-1.8). When adjusting for BMI, only the association of self-reported PCOS and MetS was attenuated (OR 1.78; CI: 0.92-3.44).

Conclusions
In Hispanic/Latina women, irregular menstrual cycles, self-reported PCOS, and any PCOS sign were associated with MetS and could indicate women at metabolic disease risk.
Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice
Authors: Deol Poonamjot , Kozlova Elena , Valdez Matthew , Ho Catherine , Yang Ei-Wen , Richardson Holly , Gonzalez Gwendolyn , Truong Edward , Reid Jack , Valdez Joseph , Deans Jonathan R , Martinez-Lomeli Jose , Evans Jane R , Jiang Tao , Sladek Frances M , Curras-Collazo Margarita C 
Published: January 2020

Abstract
Soybean oil consumption has increased greatly in the past half-century and is linked to obesity and diabetes. To test the hypothesis that soybean oil diet alters hypothalamic gene expression in conjunction with metabolic phenotype, we performed RNA sequencing analysis using male mice fed isocaloric, high-fat diets based on conventional soybean oil (high in linoleic acid, LA), a genetically modified, low-LA soybean oil (Plenish), and coconut oil (high in saturated fat, containing no LA). The 2 soybean oil diets had similar but nonidentical effects on the hypothalamic transcriptome, whereas the coconut oil diet had a negligible effect compared to a low-fat control diet. Dysregulated genes were associated with inflammation, neuroendocrine, neurochemical, and insulin signaling. Oxt was the only gene with metabolic, inflammation, and neurological relevance upregulated by both soybean oil diets compared to both control diets. Oxytocin immunoreactivity in the supraoptic and paraventricular nuclei of the hypothalamus was reduced, whereas plasma oxytocin and hypothalamic Oxt were increased. These central and peripheral effects of soybean oil diets were correlated with glucose intolerance but not body weight. Alterations in hypothalamic Oxt and plasma oxytocin were not observed in the coconut oil diet enriched in stigmasterol, a phytosterol found in soybean oil. We postulate that neither stigmasterol nor LA is responsible for effects of soybean oil diets on oxytocin and that Oxt messenger RNA levels could be associated with the diabetic state. Given the ubiquitous presence of soybean oil in the American diet, its observed effects on hypothalamic gene expression could have important public health ramifications.