bluuebunny/crossref_metadata_2025_split huggingface dataset:
China’s fight against COVID-19: What we have done and what we should do next?
Authors: Cheng Sixiang , Zhao Yuxin , Kaminga Atipatsa Chiwanda , Zhang Pingxin , Xu Huilan 
Published: March 2020

AbstractBackgroundOn 12 March, the World Health Organization Director-General declared that “the threat of a global pandemic has become a reality”, and the disease caused by the novel coronavirus, known as COVID-19, has become a global concern. Chinese efforts in curbing the virus have widely been recognized. Even the WHO has lauded the efforts of the Chinese government and advised the world to learn from China in fighting the disease. Since the outbreak of COVID-19, to curb the spread of the epidemic, the Chinese government has implemented unprecedented prevention interventions at the nationwide level. Currently, the outbreak in Wuhan is changing in a positive direction and has been effectively controlled. However, it is not clear what these measures were and how these measures changed to curb the outbreak of COVID-19 quickly. This study explored the characteristics and identified that China’s control strategies have changed the epidemiological curve of rapidly rising new confirmed cases of COVID-19. This study also seeks to expand the experiences and lessons from this outbreak.MethodsWe collected public health interventions measures from Jan 20, 2020, to 5 March 2020, and data from COVID-19 daily newly confirmed cases and daily cumulates cases to compare the control effects and changing trends. We performed a retrospective description of these intervention strategies from three stages. Besides, from the perspective of public health, the experiences and lessons exposed by this outbreak were roughly summarized.ResultsThese non-pharmacology interventions measures adopted by the Chinese government by the instruction and spirit of President Xi Jinping were timely and efficient.ConclusionsThe present study was conducted to comprehensively analyze from a social epidemiology context. The results confirmed that these radical interventions taken by the Chinese government were effective, ambitious, and agile. However, we must be aware that the epidemic situation in Wuhan is still challenging.
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Authors: Prakash Priya , Jethava Krupal P. , Korte Nils , Izquierdo Pablo , Favuzzi Emilia , Rose Indigo , Guttenplan Kevin , Dutta Sayan , Rochet Jean-Christophe , Fishell Gordon , Liddelow Shane , Attwell David , Chopra Gaurav 
Published: March 2020

ABSTRACTPhagocytosis by glial cells is essential to regulate brain function during development and disease. Given recent interest in using amyloid β (Aβ)-targeted antibodies as a therapy for patients with Alzheimer’s disease, removal of Aβ by phagocytosis is likely protective early in Alzheimer’s disease, but remains poorly understood. Impaired phagocytic function of glial cells surrounding Aβ plaques during later stages in Alzheimer’s disease likely contributes to worsened disease outcomes, but the underlying mechanisms of how this occurs remain unknown. We have developed a human Aβ1-42analogue (AβpH) that exhibits green fluorescence upon internalization into the acidic phagosomes of cells but is non-fluorescent at physiological pH. This allowed us to image, for the first time, glial uptake of AβpHin real time in live animals. Microglia phagocytose more AβpHthan astrocytes in culture, in brain slices andin vivo. AβpHcan be used to investigate the phagocytic mechanisms removing Aβ from the extracellular space, and thus could become a useful tool to study Aβ clearance at different stages of Alzheimer’s disease.
Predicting cell-type-specific non-coding RNA transcription from genome sequence
Authors: Koido Masaru , Hon Chung-Chau , Koyama Satoshi , Kawaji Hideya , Murakawa Yasuhiro , Ishigaki Kazuyoshi , Ito Kaoru , Sese Jun , Kamatani Yoichiro , Carninci Piero , Terao Chikashi 
Published: March 2020

SUMMARYTranscription is regulated through complex mechanisms involving non-coding RNAs (ncRNAs). However, because transcription of ncRNAs, especially enhancer RNAs, is often low and cell type-specific, its dependency on genotype remains largely unexplored. Here, we developedmutationeffect prediction onncRNAtranscription (MENTR), a quantitative machine learning framework reliably connecting genetic associations with expression of ncRNAs, resolved to the level of cell type. MENTR-predicted mutation effects on ncRNA transcription were concordant with estimates from previous genetic studies in a cell type-dependent manner. We inferred reliable causal variants from 41,223 GWAS variants, and proposed 7,775 enhancers and 3,548 long-ncRNAs as complex trait-associated ncRNAs in 348 major human primary cells and tissues, including plausible enhancer-mediated functional alterations in single-variant resolution in Crohn’s disease. In summary, we present new resources for discovering causal variants, the biological mechanisms driving complex traits, and the sequence-dependency of ncRNA regulation in relevant cell types.
SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission
Authors: Corman Victor M. , Rabenau Holger F. , Adams Ortwin , Oberle Doris , Funk Markus B. , Keller-Stanislawski Brigitte , Timm Jörg , Drosten Christian , Ciesek Sandra 
Published: March 2020

AbstractOral swabs, sputum and blood samples from 18 patients with SARS-CoV-2 infection were examined using real-time reverse transcription polymerase chain reaction (RT-PCR) testing. Whereas oral swabs or sputum from the lower respiratory tract were tested RT-PCR positive in all patients, RNAemia was neither detected in 3 patients without symptoms nor in 14 patients with flu-like symptoms, fever or pneumonia. The only patient with RNAemia suffered from acute respiratory distress syndrome (ARDS) and was artificially ventilated in an intensive care unit. Risk for SARS-CoV-2 transmission through blood components in asymptomatic SARS-CoV-2 infected individuals therefore seems negligible but further studies are needed.
How to evaluate the success of the COVID-19 measures implemented by the Norwegian government by analyzing changes in doubling time
Authors: Stangeland Biljana 
Published: March 2020

AbstractDoubling Time (DT) is typically calculated for growth curves that show exponential growth, such as the cumulative number of COVID-19 cases day by day. DT represents the time it takes before the number of COVID-19 cases, in a certain country or area, doubles.Throughout the ongoing COVID-19 outbreak, DT values are continually changing. These changes are influenced by the measures that are recommended by the health authorities and implemented by governments.After the government-imposed shutdowns of Nordic Countries that were announced around the 12th of March 2020, we followed the development of the DT in the region. Governments put in place measures never before experienced during peace time; working from home, closed schools and kindergartens, travel bans and social distancing. We conducted analyses to evaluate the effectiveness of these measures. Does it work? The initial set of results following the shutdown are encouraging, demonstrating a trend towards slower growth; however, this could be reversed if the measures that are in place now are abandoned too early. Premature optimism can be very costly. In this report we describe a method for monitoring the epidemic in real time and evaluating the effectiveness of the implemented measures.
COVID-19 Modelling: the Effects of Social Distancing
Authors: Bendtsen Cano Oliva , Cano Morales Sabrina , Bendtsen Claus 
Published: March 2020

AbstractThe purpose of this article is to reach all those who find it difficult to become well informed about the repercussions of a lockdown strategy to tackle the COVID-19 pandemic and to spark discussion and thought. Here we use simple stochastic simulations to evaluate different approaches taken to tackle the crisis, along with the efficiency they will hold and the number of casualties they may incur. It is clear that the less strict the social distancing the more time it will take for life to return to normal, and the more lives will be at risk. This is shown through simulations formed by an open sourced code, which allows evaluation of the outcomes from different intervention scenarios or conditions.
MinION-in-ARMS: Nanopore Sequencing To Expedite Barcoding Of Specimen-Rich Macrofaunal Samples From Autonomous Reef Monitoring Structures
Authors: Chang Jia Jin Marc , Ip Yin Cheong Aden , Bauman Andrew G. , Huang Danwei 
Published: March 2020

AbstractAutonomous Reef Monitoring Structure (ARMS) are standardised devices for sampling biodiversity in complex marine benthic habitats such as coral reefs. When coupled with DNA sequencing, these devices greatly expand our ability to document marine biodiversity. Unfortunately, the existing workflow for processing macrofaunal samples (>2-mm) in the ARMS pipeline—which involves Sanger sequencing—is expensive, laborious, and thus prohibitive for ARMS researchers. Here, we propose a faster, more cost-effective alternative by demonstrating a successful application of the MinION-based barcoding approach on the >2mm-size fraction of ARMS samples. All data were available within 3.5–4 h, and sequencing costs relatively low at approximately US$3 per MinION barcode. We sequenced the 313-bp fragment of the cytochrome c oxidase subunit I (COI) for 725 samples on both MinION and Illumina platforms, and retrieved 507–584 overlapping barcodes. MinION barcodes were highly accurate (~99.9%) when compared with Illumina reference barcodes. Molecular operational taxonomic units inferred between MinION and Illumina barcodes were consistently stable, and match ratios demonstrated highly congruent clustering patterns (≥0.96). Our method would make ARMS more accessible to researchers, and greatly expedite the processing of macrofaunal samples; it can also be easily applied to other small-to-moderate DNA barcoding projects (<10,000 specimens) for rapid species identification and discovery.
Physical interventions to interrupt or reduce the spread of respiratory viruses. Part 1 - Face masks, eye protection and person distancing: systematic review and meta-analysis
Authors: Jefferson T , Jones MA , Al-Ansary L , Bawazeer GA , Beller EM , Clark J , Conly JM , Del Mar C , Dooley E , Ferroni E , Glasziou P , Hoffmann T , Thorning S , van Driel ML 
Published: March 2020

AbstractOBJECTIVETo examine the effectiveness of eye protection, face masks, or person distancing on interrupting or reducing the spread of respiratory viruses.DESIGNUpdate of a Cochrane review that included a meta-analysis of observational studies during the SARS outbreak of 2003.DATA SOURCESEligible trials from the previous review; search of Cochrane Central Register of Controlled Trials, PubMed, Embase and CINAHL from October 2010 up to 1 April 2020; and forwardand backward citation analysis.DATA SELECTIONRandomised and cluster-randomised trials of people of any age, testing the use ofeye protection, face masks, or person distancing against standard practice, or a similar physical barrier. Outcomes included any acute respiratory illness and its related consequences.DATA EXTRACTION AND ANALYSISSix authors independently assessed risk of bias using the Cochrane tool and extracted data. We used a generalised inverse variance method for pooling using a random-effects model and reported results with risk ratios and 95% Confidence Intervals (CI).RESULTSWe included 15 randomised trials investigating the effect of masks (14 trials) in healthcare workers and the general population and of quarantine (1 trial). We found no trials testing eye protection. Compared to no masks there was no reduction of influenza-like illness (ILI) cases (Risk Ratio 0.93, 95%CI 0.83 to 1.05) or influenza (Risk Ratio 0.84, 95%CI 0.61-1.17) for masks in the general population, nor in healthcare workers (Risk Ratio 0.37, 95%CI 0.05 to 2.50). There was no difference between surgical masks and N95 respirators: for ILI (Risk Ratio 0.83, 95%CI 0.63 to 1.08), for influenza (Risk Ratio 1.02, 95%CI 0.73 to 1.43). Harms were poorly reported and limited to discomfort with lower compliance. The only trial testing quarantining workers with household ILI contacts found a reduction in ILI cases, but increased risk of quarantined workers contracting influenza. All trials were conducted during seasonal ILI activity.CONCLUSIONSMost included trials had poor design, reporting and sparse events. There was insufficient evidence to provide a recommendation on the use of facial barriers without other measures. We found insufficient evidence for a difference between surgical masks and N95 respirators and limited evidence to support effectiveness of quarantine. Based on observational evidence from the previous SARS epidemic included in the previous version of our Cochrane review we recommend the use of masks combined with other measures.
Determinants of customers' choice of dining-related services: the case of Taipei City
Authors: Cheng Ching-Chan , Wu Hung-Che , Tsai Ming-Chun , Chang Yu-Yuan , Chen Cheng-Ta 
Published: March 2020

PurposeThis study aims to extract determinants of customers' choice of dining-related services (CDS) to understand their attitudes and habits for dining-related services. Moreover, it classifies restaurant customers into several clusters based on their CDS factors and further analyzes the differences in the preferences and habits for dining-related services among various clusters.Design/methodology/approachThis study extracts the CDS factors using principal component analysis and identifies construct validity of the CDS factors through the results of confirmatory factor analysis. Then, it divides the restaurant customers in Taipei City into different clusters through cluster analysis to explore the habits and preferences for dining-related services in each cluster.FindingsThe study results show that the extracted six CDS factors, including service commitment, dietary preferences, design styles, additional value, delicate information collection, and dining environments. Dietary preferences, service commitment and additional value factor are the most important CDS factors for restaurant customers in Taipei City. This study divides 1,029 restaurant customers in Taipei City into three clusters based on the CDS factors through cluster analysis. The differences in the preferences and habits for dining services among three clusters have been discussed in the context in detail. Finally, this study develops eight service strategies and determines the order of execution of the eight service strategies for each cluster of customers.Originality/valueThe findings will help restaurant operators segment the market, target market customers, carry out service positioning and develop marketing strategies to respond to the highly competitive restaurant market and achieve sustainable restaurant operations.
Entrepreneurial aspirations: economic development, inequalities and cultural values
Authors: Morales-Alonso Gustavo , Núñez Guerrero Yilsy , Aguilera Juan Francisco , Rodríguez-Monroy Carlos 
Published: March 2020

PurposeThis study aims at shedding light on entrepreneurial aspirations on both developed and developing economies, in terms of contextual and individual values. Among the former, economic development and inequalities are sought after, while among the latter national culture is the variable under study.Design/methodology/approachThe data used are extracted from the Global Entrepreneurship Monitor for a panel of countries, where the entrepreneurial aspirations of individuals of each country are measured through the Total early-stage Entrepreneurial Activity (TEA). The influence of cultural values as defined by Hofstede (individualism-collectivism (IDV), masculinity–femininity (MAS) and uncertainty avoidance (UAI)), moderated by the development level of the country and the existing inequalities are analyzed through artificial neural network (ANN) and multilayer perceptron (MLP) techniques.FindingsResults show that in the post-crisis era, entrepreneurial aspirations are negatively linked to individualism in developing countries. In developed countries, however, entrepreneurship is not linked to individualism but to inequalities.Originality/valueEntrepreneurial aspirations have not been thoroughly studied in the post-crisis era. We prove that entrepreneurial orientations have changed, together with the world, in the last decade. Cultural differences between countries tend to moderate, especially among developed ones, which speak of homogenization of national cultures. In this regard, inequalities are the determining factor. Contrarily, in developing countries, the differences in individualism are noticeable when it comes to analyzing entrepreneurial aspirations.
Conundrum of resource sharing in Zimbabwe: a case of academic libraries
Authors: Chisita Collence Takaingenmhamo , Fombad Madeleine C. 
Published: March 2020

Purpose
The purpose of this paper is to explore the challenges and opportunities for Zimbabwe’s academic libraries in their endeavour to provide quality services. It will examine how library consortia, namely, the Zimbabwe University Library Consortium (ZULC) and the College and Research Libraries Consortium (CARLC), have been able to provide for the information needs of their users at a time when budgets are inadequate and subscription costs to journals remain unaffordable. It will examine how academic libraries, through resource sharing platforms, have been able to exploit ubiquitous technologies and build on from the traditional interlibrary loan (ILL). The paper will recommend a strategy based on a model to strengthen access to scholarship through resource sharing.

Design/methodology/approach
The researcher opted for a qualitative research design. A purposive sample of 32 participants drawn from ten academic librarians located in Zimbabwe was used to collect the information. The participants were chosen because of their involvement in resource-sharing activities. The participants were drawn from the two library consortia, namely, CARLC and ZULC. Data for the study was collected using structured interviews.

Findings
The findings revealed that resource sharing was critical for the survival of academic libraries in Zimbabwe. The study found out that resource sharing was the only option to overcome the challenges of the paywall. It highlighted the need for a concerted effort of all academic institutions in adapting a model that provides for the diverse needs of members with regard to widening access to scholarship. However, in spite of the success of library consortia in enhancing resource sharing in Zimbabwe, there are challenges that require the concerted effort of all academic institutions in coming up with a model that best provides for the diverse needs of members with regard to resource sharing.

Practical implications
The results of the study will be useful in providing a long-term strategy for enhancing resource sharing among academic libraries in Zimbabwe in their endeavor to support teaching, learning and research.

Originality/value
There is a scarcity of scholarly studies on resource sharing initiatives among academic libraries in Zimbabwe. This study is unique because it tackles the experiences of the academic libraries in overcoming the challenges of the paywall.
What drives the boom in outward FDI from India?
Authors: Saikia Munmi , Das Khanindra Ch. , Borbora Saundarjya 
Published: March 2020

PurposeThe Indian economy has experienced a boom in outward FDI (OFDI) in 2006. The study aims at exploring the factors that drive the boom in OFDI of Indian firms.Design/methodology/approachThe participation of a firm in OFDI is a two-stage process -first, the decision to internationalization and second, how much to invest. We employ a two-stage model to decompose the effects on the decision to internationalization from effects on how much to invest. The two-stage model has the advantage of allowing us to estimate separately the probability of internationalization by a firm – Pr(OFDI > 0) – and the expected volume of investment, E(OFDI|OFDI > 0). The former is estimated by the probit model and the latter is estimated by the ordinary least square model.FindingsThe study finds that prior experience and institutional advantage can strongly drive the internationalization of Indian multinationals. The study also examines the relative importance of two aspects of prior knowledge – length of prior knowledge and depth of prior knowledge on OFDI of Indian firms. The study finds that the depth of prior knowledge is a must influential driver of OFDI in comparison to its length.Originality/valueThe present study is a novel attempt to investigate, ‘What drives the boom in OFDI from India?’
Project manager roles in a public change project: the case of a municipal merger
Authors: Karlsen Jan Terje , Farid Parinaz , Torvatn Tim 
Published: March 2020

PurposeThis paper investigates the emphasis placed on different managerial roles by the project manager in a public merger and change project.Design/methodology/approachA research model was designed based on six management roles: leader, resource allocator, spokesman, entrepreneur, liaison and monitor. Empirical data were collected using in-depth interviews. The studied case concerns a large public merger and change project between two municipalities in Norway.FindingsThe paper reveals that the project manager emphasized the externally oriented entrepreneur role mostly. The internally oriented resource allocator role that focuses on managing the project was least emphasized. The research identifies a gap between needed and actual competence in basic project management as a barrier to exercise the resource allocator role more thoroughly.Research limitations/implicationsFuture research should investigate other public merger and change projects so that these findings may be generalized.Practical implicationsThis research concludes that project managers in public change projects should be more internally oriented towards the resource allocator role. Furthermore, public project managers need to make sure that they possess the necessary technical project management competence to practice the resource allocator role effectively.Originality/valueRather than stressing the importance of leadership in general to manage a project, this paper is original as it applies a set of management roles to empirically study what a public project manager practice.
Family-friendly practices in the organization: a citation analysis
Authors: Garg Shalini , Agrawal Punam 
Published: March 2020

PurposeThe objective of the study is to identify the themes of “family friendly practices” and to perform a literature review. The research aims to identify the emerging trends in the area of “family friendly practices” by carrying out an exhaustive literature review.Design/methodology/approachThe study synthesizes the literature between the years 2010 and 2019. First of all, 150 research articles were identified by keyword search, bibliography and citation search, out of which 57 research articles were selected on the basis of the most sound theoretical background and maximum literature contribution. The citation analysis method was performed on these studies in order to study the journals, authors by using Google Scholar, ResearchGate, the international database Science Citation Index and SCImago Journal Ranking.FindingsThe author citation count shows that the research topic is still getting recognition and the research in this area is increasing. The finding of the research is that the current research in family-friendly practices has focused mainly on seven topics: availability and usability of family-friendly policy, job satisfaction, organizational performance, supervisor or manager support, work–life conflict, employee turnover employee retention and women’s employment.Originality/valueThe study may provide valuable inputs to the HRD practitioners, managers, research scholars, to understand the recent trends in the field of family-friendly policy. As per the best knowledge of the author, this is the first study on family-friendly practices using citation analysis.