num_pages: 488
description: Designed to provide a comprehensive step-by-step approach to organic process research and development in the pharmaceutical fine chemical and agricultural chemical industries this book describes the steps taken following synthesis and evaluation to bring key compounds to market in a cost-effective manner. It describes hands-on step-by-step approaches to solving process development problems including route reagent and solvent selection; optimising catalytic reactions; chiral syntheses; and green chemistry. Second Edition  Reflects the current thinking in chemical process R&amp;D for small molecules  Retains similar structure and orientation to the first edition.  Contains approx. 85% new material  Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)  Some new/expanded topics (e.g. green chemistry genotoxins enzymatic processes)  Replaces the first edition although the first edition contains useful older examples that readers may refer to
language: English
title: Practical Process Research and Development: A guide for Organic Chemists
publisher: Academic Press