description: This important volume is mainly concerned with the development of methods for "sequencing" -- that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.
language: English
title: Selected Papers of Frederick Sanger: (With Commentaries)
titlecomplete: Selected Papers of Frederick Sanger: (With Commentaries) (Series in 20th Century Biology)
publisher: World Scientific Pub Co Inc