BACKGROUND: It is quite common that @entity1 suffering from @entity73 only visit a doctor when the symptoms have already reached an advanced stage. This is often due to a fear of @entity195 or a dread of exhausting diagnostic procedures and exposure of personal details; however, an early diagnosis and therapy increases the chance of preserving the quality of life for a longer period of time. OBJECTIVES: Evaluation of a risk assessment for @entity195 by magnetic resonance imaging (MRI) with respect to the acceptance and value by @entity1 . METHODS: In this prospective preventive study 106 subjects between the age of 39 and 89 years (median age 68 years) with general risk factors were included and underwent a risk assessment for @entity195 by standard MRI of the brain using a 1  T open MRI with subsequent hippocampal volumetry. @entity1 were stratified into two distinct subgroups according to the individual hippocampal @entity194 status, one with elevated and the other with reduced risk. All @entity1 were thoroughly interviewed regarding anxieties and mental well-being before and after the risk assessment. RESULTS: As expected, @entity1 with a reduced risk had a significant improvement in well-being and a reduction of fears and worries after the examination. Neither a significant deterioration of the mental situation nor an increase of fears and worries was found for @entity1 with an elevated risk. Of the @entity1 90   % stated that MRI-based risk stratification generated positive perspectives for the future. The assessment revealed a high acceptance by most of the @entity1 (94   %). CONCLUSION: An MRI-based risk assessment is beneficial to the @entity1 's quality of life and as a low threshold approach may induce more individuals with concerns to take advantage of an early diagnosis of @entity195 .

[Value and acceptance of risk assessment for XXXX ].

@entity1 :: ('9606', 'Species') :: ['participants', 'patient', 'Participants', 'people'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment'] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy'] @entity195 :: ('MESH:D000544', 'Disease') :: ["Alzheimer's disease"]
@entity195 :: (MESH:D000544,Disease) :: ['Alzheimer's disease']
