OBJECTIVE: To assess the frequency and characteristics of hilar and mediastinal involvement in @entity1 with @entity2883 ( @entity2883 ). METHODS: A @entity1 with @entity2883 presented with the unusual finding of a mediastinal mass, prompting a comprehensive review of 302 @entity1 records from 2 @entity2883 registries to obtain evidence of @entity3018 or mediastinal masses. Clinic progress notes and findings of chest imaging studies (routine imaging and computed tomography) were reviewed for the presence of @entity3329 , mediastinal masses, or mediastinal @entity3329 . All radiographs and surgical pathology specimens from these lesions were reviewed. RESULTS: Six examples of mediastinal or hilar involvement (2.0%) were identified among 302 @entity1 with @entity2883 . Three of these 6 @entity1 had mediastinal masses. One @entity1 with a mediastinal mass also had mediastinal @entity3329 . Two of the @entity1 with mediastinal masses had lung parenchymal lesions. The remaining 3 @entity1 had enlarged hilar lymph nodes in addition to pulmonary parenchymal lesions. All of the @entity1 were treated with @entity288 and cytotoxic drugs. Followup information was available on all @entity1 . Two @entity1 died. In the remaining 4 @entity1 , the mediastinal mass or @entity3329 decreased in size or resolved after 2 months of immunosuppressive therapy. CONCLUSION: In the past, @entity3018 and/or mediastinal mass have been considered unlikely features of @entity2883 , and their presence has prompted consideration of an alternative diagnosis. Although this caution remains valuable, the present retrospective review of data from 2 large @entity2883 registries illustrates that such findings may rarely be a part of the spectrum of @entity2883 . Because these findings are uncommon, they necessitate consideration of a primary or concurrent @entity5 in the diagnostic evaluation.

Mediastinal mass and XXXX : rare thoracic manifestations of @entity2883 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['lymphadenopathy', 'hilar lymphadenopathy'] @entity3018 :: ('MESH:D009377', 'Disease') :: ['hilar adenopathy'] @entity5 :: ('MESH:D009369', 'Disease') :: ['infection or malignancy'] @entity2883 :: ('MESH:D014890', 'Disease') :: ['WG', "Wegener's granulomatosis", 'WG chest disease'] @entity288 :: ('MESH:D000305', 'Chemical') :: ['corticosteroids']
@entity3018 :: (MESH:D009377,Disease) :: ['hilar adenopathy']
