Internal radiation therapy selectively targets beta- or alpha-emitting radionuclides to the area of the @entity5 tissue, and is therefore capable of treating disease regardless of the location and number of foci. The biological effect of internal radiation therapy is thought to be different from that of conventional external beam radiation. @entity259 : The local recurrence and metastatic lesions from differentiated @entity259 can be controlled with 131I administration. Even though the @entity1 does not have macroscopic disease, 131I is also utilized for thyroid remnant ablation in locally advanced cases. Recently, the maximum tolerable dose can be calculated based on the dosimetry of each @entity1 , and safely administered. The therapeutic effect of this method is superior to the fixed dose method. 131I-MIBG: 131I-MIBG is taken up by sympathetic neurons as well as a group of @entity5 originating in the neural crest, especially phecromocytomas and @entity521 . The various symptoms caused by the hypersecretions of hormone-producing @entity5 can be improved. @entity158 palliation of bone @entity3 : @entity158 palliation using 89Sr is a very promising option in treating @entity1 with painful bone @entity3 . The @entity158 palliation mechanism of 89Sr is different from other drugs; therefore, complimentary usage is reasonable. The symptomatical improvement can last for several months, thus helping to maintain the quality of life of the @entity1 .

[Internal radiation therapy for malignant XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain'] @entity521 :: ('MESH:D009447', 'Disease') :: ['neuroblastomas'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity259 :: ('MESH:D013964', 'Disease') :: ['Thyroid cancer', 'thyroid cancers']
@entity5 :: (MESH:D009369,Disease) :: ['neoplasm']
