OBJECTIVE: To gain a broader appreciation of the clinical presentation, operative treatment, and outcome of @entity1 with @entity82 involving the skull base. DESIGN: Retrospective review of a clinical case series. SETTING: A single tertiary academic medical center. @entity1 : Twenty-one @entity1 with histopathologically confirmed @entity82 involving the skull base cared for over a 15-year-period (1983-1998). MAIN OUTCOME MEASURES: Clinical and radiographic location of the @entity82 lesions within the skull base, clinical presentation, surgical intervention, and clinical outcome were tabulated for each @entity1 . RESULTS: The ethmoids were most commonly involved (71%), followed by the sphenoid (43%), frontal (33%), maxilla (29%), temporal (24%), parietal (14%), and occipital (5%) bones. The most common presenting features included atypical @entity158 and @entity10 , complaints referable to the sinuses, proptosis and @entity892 , @entity393 , and @entity1183 . Surgical treatment, guided by clinical presentation, ranged from simple biopsy with conservative follow-up to craniofacial resection. CONCLUSIONS: @entity82 can present in myriad ways within the skull base. Modern imaging modalities and histopathologic analysis have made diagnosis relatively straightforward. Surgery, particularly in such a challenging region as the skull base, should be reserved for @entity1 with functional impairment or a @entity85 . Because of the benign nature of the condition, the surgery itself should be relatively conservative, with the primary goal being preservation of existing function.

XXXX involving the skull base and temporal bone.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrous dysplasia', 'Fibrous dysplasia'] @entity1183 :: ('MESH:D006987', 'Disease') :: ['facial numbness'] @entity158 :: ('MESH:D010146', 'Disease') :: ['facial pain'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss'] @entity892 :: ('MESH:D004172', 'Disease') :: ['diplopia'] @entity85 :: ('MESH:D009140', 'Disease') :: ['cosmetic deformity'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache']
@entity82 :: (MESH:D005355,Disease) :: ['Fibrous dysplasia']
