BACKGROUND: @entity1 with @entity101 (BP) often exhibit @entity1112 , an aggregation of abnormalities in @entity1735 and lipoprotein metabolism associated with increased risk of @entity301 ( @entity301 ). The present study evaluated the effects of a 6-month intervention involving either aerobic exercise training alone (EX only) or exercise combined with a structured @entity353 program (EX + WL) on @entity301 risk factors associated with @entity1112 . METHODS: A total of 53 @entity1 and @entity1 were selected from a larger behavioral intervention trial, who showed the @entity3190 , @entity2299 , and high BP characteristic of @entity1112 . @entity1 were randomly assigned to EX only (n = 21), EX + WL (n = 21), or a waiting list control group (n = 11). Before and following treatment, @entity1 underwent measurement of @entity413 tolerance, lipid levels, and clinical BP. RESULTS: @entity1717 responses to @entity413 challenge were significantly reduced in both the EX + WL group (P<.001) and the EX-only group (P =.003). @entity1 who showed the largest amount of @entity353 showed the most robust improvements in abnormal insulin responses (EX + WL group, 47% reduction; EX-only group, 27% reduction). Diastolic BP was significantly reduced in the EX + WL group (96 +/- 4 to 87 +/- 5 mm Hg [mean +/- SD]; P =.01), but not in the EX-only group (93 +/- 4 to 89 +/- 5 mm Hg [mean +/- SD]; P =.08). Lipid profile was not significantly improved by either intervention. CONCLUSION: These results suggest that EX + WL is an effective treatment for @entity3190 and lowering of diastolic BP in @entity1 with the @entity1112 .

Effects of exercise and @entity353 on cardiac risk factors associated with XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Patients', 'patients', 'Participants', 'men'] @entity101 :: ('MESH:D006973', 'Disease') :: ['high blood pressure'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity301 :: ('MESH:D003327', 'Disease') :: ['CHD', 'coronary heart disease'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity1112 :: ('MESH:D040181', 'Disease') :: ['syndrome X'] @entity1735 :: ('CHEBI:16646', 'Chemical') :: ['carbohydrate'] @entity1717 :: ('MESH:D044903', 'Disease') :: ['Hyperinsulinemic'] @entity3190 :: ('MESH:D006946', 'Disease') :: ['hyperinsulinemia'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity1112 :: (MESH:D040181,Disease) :: ['syndrome X']
