BACKGROUND: In a previous study, we demonstrated that @entity1 with early onset @entity1714 had greater instability of accommodation than a group of emmetropic @entity1 . Since that study was correlational, we were unable to determine the causal relationship between this and @entity2789 . To address this, we examined the @entity1 two years later. We predicted that if accommodative instability was causing the @entity2789 , instability at Visit 1 should predict the @entity2516 at Visit 2. Additionally, instability at Visit 1 should predict @entity2789 . METHODS: Thirteen myopic and 16 emmetropic @entity1 were included in the analysis. Dynamic measures of accommodation were made using eccentric photorefraction (PowerRefractor) while @entity1 viewed targets set at three distances (accommodative demands), namely, 0.25 metres (4.00 D demand), 0.5 metres (2.00 D demand) and 4.00 metres (0.25 D demand). RESULTS: Both @entity2516 and accommodative instability at Visit 1 were highly correlated with the same measures at Visit 2. @entity1 with @entity1714 showed greater instability of accommodation (0.38 D) than @entity1 with emmetropia (0.26 D) at the 4.00 D target on Visit 1 and this instability of accommodation weakly predicted @entity2789 . CONCLUSIONS: The results presented in the present study suggest that instability of accommodation accompanies @entity2789 , although a casual relationship cannot be established.

Accommodative instability: relationship to progression of early onset XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Children'] @entity2789 :: ('MESH:D018450', 'Disease') :: ['myopic progression'] @entity1714 :: ('MESH:D009216', 'Disease') :: ['myopia'] @entity2516 :: ('MESH:D012030', 'Disease') :: ['refractive error']
@entity1714 :: (MESH:D009216,Disease) :: ['myopia']
