OBJECTIVE: To examine the factors affecting outcome in @entity1 with advanced @entity354 . DESIGN: Retrospective analysis. SETTING: University tertiary referral center. @entity1 : Thirty-seven @entity1 with advanced @entity354 and no previous antireflux surgery. INTERVENTIONS: Thirty @entity1 underwent Collis gastroplasty for esophageal lengthening and Belsey partial fundoplication. Seven @entity1 with @entity3332 and global loss of esophageal body motility who underwent primary esophagectomy and reconstruction were used as a comparison group. OUTCOME MEASURES: Symptomatic outcome in all 37 @entity1 was assessed by questionnaire at a median of 25 months (range, 5-156 months) after surgery. In a subset of 11 @entity1 undergoing the Collis-Belsey procedure, outcome was measured using 24-hour pH and results of motility studies. RESULTS: The Collis-Belsey procedure was successful in relieving symptoms of @entity354 in 21 (70%) of the 30 @entity1 . The outcome was excellent or good in 16 (89%) of 18 @entity1 who presented with symptoms other than @entity1282 , but only in 5 (42%) of 12 @entity1 with @entity1282 (P = .01). The outcome was particularly poor if @entity1282 was associated with a previously dilated @entity3332 . Persistent or induced @entity1282 was the reason for failure in all but 1 @entity1 . Results of 24-hour esophageal pH studies were returned to normal in 8 (73%) of 11 @entity1 undergoing postoperative evaluation. Contraction amplitudes in the distal esophagus and the prevalence of simultaneous contractions in these segments did not change after the operation. All 7 @entity1 who underwent primary esophagectomy were classified as having an excellent or good outcome and were relieved of their reflux symptoms, including @entity1282 . Six of these could eat 3 meals per day and enjoyed an unrestricted diet. CONCLUSIONS: The outcome of the Collis-Belsey procedure in @entity1 with advanced @entity354 without @entity1282 is excellent. It is less so in @entity1 with @entity1282 as a preoperative symptom. Esophagectomy can provide a good outcome in @entity1 who have a combination of @entity1282 stricture and a profound loss of esophageal motility.

Treatment of advanced XXXX with Collis gastroplasty and Belsey partial fundoplication.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity3332 :: ('MESH:D004940', 'Disease') :: ['esophageal stricture'] @entity1282 :: ('MESH:D003680', 'Disease') :: ['dysphagia'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux', 'gastroesophageal reflux disease']
@entity354 :: (MESH:D005764,Disease) :: ['gastroesophageal reflux disease']
