BACKGROUND: Anomalous junction of the pancreaticobiliary ductal system (AJPBDS) is a @entity154 in which the junction is located outside the duodenal wall. Recently, attention has been focused on the high incidence of @entity5 in this @entity154 . The purpose of this study was to clarify the clinicopathological features of this @entity154 and to determine the appropriate surgical approach for @entity1125 associated with AJPBDS. METHODS: The data for 38 @entity1 with AJPBDS, including 14 who had been treated for @entity1125 (2 with @entity1126 and 12 with @entity1086 ), were retrospectively reviewed. We assessed the clinical features, characteristics of the @entity5 , operative procedure, and outcome for each @entity1 . RESULTS: The incidence of @entity5 in AJPBDS was 17.8% (2 @entity1 with @entity1126 and 3 with @entity1086 ) in the bile duct dilatation group (n = 28) and 90% (9 @entity1 with @entity1086 ) in the no-dilatation group (n = 10) . The mean length of the common channel was 24.7 mm (range 20 to 35 mm) . Resection with lymphadenectomy was performed in 9 (64.3%) of 14 @entity1 , and curative resection in 5 of these 9 @entity1 . Ten (71%) of the 14 @entity1 had lymph node involvement noted either at the time of initial diagnosis or at surgery. The incidence of lymph node @entity3 was closely related to the depth of @entity5 involvement. Ten @entity1 died of recurrence or primary @entity5 , from 3 to 30 months after operation. Four @entity1 are still alive without recurrent disease from 2.5 to 13 years after operation. CONCLUSION: For @entity1 with AJPBDS without bile duct dilatation, prophylactic cholecystectomy is recommended even if no malignant lesion is found in the gallbladder because of the high incidence of @entity1086 and the poor prognosis. Both early detection and curative resection of the @entity5 are essential for successful treatment of @entity1125 .

Biliary tract XXXX accompanied by anomalous junction of pancreaticobiliary ductal system in adults.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity154 :: ('MESH:D000013', 'Disease') :: ['anomaly', 'congenital anomaly'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer', 'malignancy'] @entity1126 :: ('MESH:D001650', 'Disease') :: ['bile duct cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity1086 :: ('MESH:D005706', 'Disease') :: ['gallbladder cancer'] @entity1125 :: ('MESH:D001661', 'Disease') :: ['biliary tract cancer']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
