Seventeen @entity235 were trained in a three-choice auditory spatial delayed response task, guided by auditory stimulus, at a 10 s delay to a criterion of 90% correct responses in 90 consecutive trials. Four @entity235 then received bilateral anterior @entity75 ( @entity1129 ), 6 @entity235 received hippocampal lesions (H), and 7 @entity235 served as controls ( @entity20844 reached postoperative criterion immediately while groups @entity1129 and H needed additional training. When subsequently tested at longer delays and with distractions, the group H animals performed more poorly than either the @entity1129 or C animals. Further, the group H @entity235 were again impaired when they retrained at a 10 s delay. In the second phase, the group H and @entity1129 animals received a second lesion forming a group (HAT) with bilateral lesions to both the hippocampus and the anterior temporal lobe. Unexpectedly, @entity235 from group HAT were unimpaired in either postoperative retraining or during performance task and distractions. The results emphasize the importance of the hippocampus in spatial delayed response with an acoustic cue. Effect of combined lesions after extensive training is discussed. Data might support the view, that the hippocampus plays time limited role in memory storage.

Effects of the anterior XXXX , separate or combined with hippocampal damage, on spatial delayed responses guided by auditory stimulus.

@entity235 :: ('9615', 'Species') :: ['dogs'] @entity20844 :: ('158899', 'Species') :: ['C). Group C'] @entity75 :: ('MESH:D001927', 'Disease') :: ['temporal lobe lesions'] @entity1129 :: ('MESH:D001260', 'Disease') :: ['AT']
@entity75 :: (MESH:D001927,Disease) :: ['temporal lobe lesions']
