AIM: Transanal endoscopic microsurgery (TEM) was originally invented by Buess (1) for the treatment of @entity652 . Its indications have progressively expanded to include larger and more @entity1442 . The aim of the study was to report the results of TEM used for the treatment of circumferential rectal lesions. METHOD: We retrospectively reviewed the medical records of 17 consecutive @entity1 (median age 69 (32-89) years; 9 male) who underwent TEM for a circumferential @entity75 in our department between September 2010 and January 2015. RESULTS: The median distance from the anal verge was 4 (3-11) cm, the median longitudinal extent was 7 (3-10) cm and the median surface area was 75 (40-255) cm(2) . An end-to-end @entity254 without proximal bowel mobilization was completed endoscopically in all cases. The median operating time was 120 (40-240) min. Persistent, endoscopically uncontrollable endoluminal bleeding in one @entity1 was successfully treated with a second TEM procedure. One @entity1 underwent preoperative radiotherapy for @entity420 detected at the preoperative assessment. Surgical histology showed a pT3 @entity5 in one @entity1 who refused further surgery, a pT2 @entity5 in two who subsequently underwent abdominoperineal resection, a pT1 @entity5 in four and a ypT0 in one @entity1 . All are presently free of disease. No @entity1 developed @entity322 or @entity250 was observed. Four @entity1 required @entity384 for @entity850 . CONCLUSION: TEM is a feasible and safe technique for large circumferential lesions with a satisfactory outcome. Preoperative staging may be inaccurate. This article is protected by copyright. All rights reserved.

Transanal endoscopic microsurgery for giant circumferential XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity322 :: ('MESH:D014549', 'Disease') :: ['faecal incontinence'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['rectal lesion'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity384 :: ('MESH:D002311', 'Disease') :: ['endoscopic balloon dilatation'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['advanced lesions'] @entity652 :: ('MESH:D000236', 'Disease') :: ['infraperitoneal rectal adenomas'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity250 :: ('MESH:D012735', 'Disease') :: ['urinary or sexual dysfunction']
@entity652 :: (MESH:D000236,Disease) :: ['rectal adenomas']
