A diagnostic tool to detect early @entity8 before it becomes irreversible would be useful in @entity82 . This study was carried out to evaluate the role of Doppler sonography and Tc-99m DTPA renography in the detection of early @entity8 in @entity1 with different grades of @entity1575 . Renal arteries of 43 @entity1 with @entity82 and normal renal function tests were compared with 15 age and gender matched normal subjects as a control group using colour Doppler sonography and Tc-99m DTPA scintigraphy. The @entity1 were categorized into three groups, A (14), B (14) and C (15), according to a modified @entity1 's classification that assesses the severity of @entity1575 . Doppler results revealed a highly significant increase in both the @entity392 and resistive indices in groups B and C compared with either group A @entity1 or control subjects and in group C compared with group B (P < 0.001) in the main renal arteries as well as in the interlobar and arcuate arteries. Insignificant differences were observed between group A and controls (PI: control 0.96+/-0.08, group A 0.95+/-0.07, group B 1.26+/-0.06, group C 1.48+/-0.06; RI: control 0.57+/-0.02, group A 0.58+/-0.02, group B 0.66+/-0.01, group C 0.72+/-0.02). Abnormal renograms in the form of delayed appearance (34+/-14.6 s), diminished blood flow bilaterally with prolonged secretory (12+/-4.5 min) and excretory phases (> 30 min) and poor response to intravenous @entity1483 were only observed in group C @entity1 . Radionuclide computed glomerular filtration rate was within the normal range in @entity1 of group A (81+/-9.5 ml/min) and group B (78+/-8.4 ml/min) and reduced only in @entity1 of group C (34+/-14.5 ml/min). Thus Doppler sonography can detect an increase in renal vascular resistance in @entity1 with moderately severe @entity82 ( @entity1 grade B) when renography was normal. We conclude that Doppler sonography can be used for earlier identification of cirrhotic @entity1 with a higher risk of impending @entity177 earlier than renography and may also be used to guide therapeutic approaches.

XXXX in @entity1575 : renal duplex Doppler US vs. scintigraphy for early identification.

@entity1 :: ('9606', 'Species') :: ['Child', 'patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal dysfunction'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity1483 :: ('MESH:D005665', 'Chemical') :: ['frusemide'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity392 :: ('MESH:D014012', 'Disease') :: ['pulsatility'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['liver cirrhosis']
@entity8 :: (MESH:D007674,Disease) :: ['Renal dysfunction']
