INTRODUCTION: Treatment of early @entity418 depends on the extent of the @entity5 and presence of regional lymph node @entity3 .(RNM). Short axis diameter>10mm is typically used to detect RNM. However, clinical determination of RNM is inaccurate and can result in inappropriate treatment. Purpose of this study is to evaluate the accuracy of a single linear measurement ( @entity851 >10mm) of regional nodes on CT in predicting nodal @entity3 , in @entity1 with early @entity418 and whether using a mean diameter value ( @entity851 +long axis/2) as well as nodal shape improves cN designation. METHODS: CTs of 49 @entity1 with @entity7487 @entity420 treated with surgical resection alone were reviewed retrospectively. Regional nodes were considered positive for @entity5 when round or ovoid and mean size>5mm adjacent to the @entity5 and>7mm when not adjacent. Results were compared with pN status after esophagectomy. RESULTS: 18/49 @entity1 had pN+ at resection. Using a single @entity851 diameter>10mm on CT, nodal @entity3 (cN) was positive in 7/49. Only 1 of these @entity1 was pN+ at resection (sensitivity 5%, specificity 80%, accuracy 53%). Using mean size and morphologic criteria, cN was positive in 28/49. 11 of these @entity1 were pN+ at resection (sensitivity 61%, specificity 45%, accuracy 51%). EUS with limited FNA of regional nodes resulted in 16/49 @entity1 with pN+ being inappropriately designated as cN0. CONCLUSIONS: Evaluation of size, shape and location of regional lymph nodes on CT improves the sensitivity of cN determination compared with a @entity851 measurement alone in @entity1 with @entity7487 @entity418 , although clinical utility is limited.

Early clinical esophageal XXXX ( @entity7487 ): Utility of CT in regional nodal @entity3 detection and can the clinical accuracy be improved?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity851 :: ('MESH:D006130', 'Disease') :: ['short axis'] @entity7487 :: ('1489', 'Gene') :: ['cT1'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumor', 'malignancy'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma']
@entity420 :: (MESH:D000230,Disease) :: ['adenocarcinoma']
