BACKGROUND: Endoscopic management of @entity850 has not been systemically studied. The aim was to evaluate endoscopic balloon therapy of pouch strictures in @entity29 ( @entity29 ) @entity1 with @entity4628 and to identify risk factors for pouch failure for those @entity1 . METHODS: Consecutive @entity29 @entity1 with pouches from the @entity5042 Clinic who underwent nonfluoroscopy-guided outpatient endoscopic therapy were studied. The location, number, degree (range 0-3), and length of strictures and balloon size were documented. Efficacy and safety were evaluated with univariate and multivariate analyses. RESULTS: A total of 150 @entity1 with pouch strictures were studied. Stricture locations were at the pouch inlet (n = 96), outlet (n = 73), afferent limb (n = 33), and pouch body (n = 2). A cumulative of 646 strictures were endoscopically dilated, with a total of 406 pouchoscopies. The median stricture score was 1 (interquartile range [IQR] 1-2); the median stricture length was 1 (IQR 0.5-1.25) cm, and the median balloon size was 20 (IQR 18-20) mm. Of 406 therapeutic endoscopies performed, there were two perforations (0.46%) and four transfusion-required bleeding (0.98%). The 5-, 10-, and 25-year pouch retention rates were 97%, 90.6%, and 85.9%, respectively. In a median follow-up of 9.6 (IQR 6-17) years, 131 @entity1 (87.3%) were able to retain their pouches. The number of strictures and underlying diagnosis were independent risk factors for pouch failure in the Cox regression model. CONCLUSIONS: Endoscopic treatment of pouch stricture appears to be efficacious and generally safe to perform in experienced hands. Underlying diagnosis of @entity30 of the pouch and surgery-related strictures and multiple strictures were the risk factors for pouch failure.

Efficacy and safety of endoscopic treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4628 :: ('MESH:D007077', 'Disease') :: ['ileal pouches'] @entity5042 :: ('MESH:D019449', 'Disease') :: ['Pouchitis'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease', 'IBD'] @entity850 :: ('MESH:D003251', 'Disease') :: ['ileal pouch strictures'] @entity30 :: ('MESH:D003424', 'Disease') :: ["Crohn's disease"]
@entity850 :: (MESH:D003251,Disease) :: ['ileal pouch strictures']
