A review of 1,236 @entity1 admitted to The Mount Sinai Hospital with @entity29 between 1960 and 1979 yielded 75 cases (6%) with @entity137 of the colon. There were 61 cases among 613 @entity1 (10%) with @entity31 ( @entity31 ), and 14 of 623 (2.3%) with @entity30 ( @entity30 ). Fifty-nine of the 75 @entity1 (79%) underwent surgery during their hospitalization with @entity137 . Twelve of the 75 @entity1 (16%) died. Both @entity31 and @entity30 groups had similar mean ages at onset of @entity1960 (32 years and 31 years, respectively) and at development of @entity137 (37 years); similar durations of @entity66 (4.8 and 5.9 years) and of @entity137 prior to surgery (11 days and 13 days); and similar anatomic distributions of disease. Both @entity31 and @entity30 also had similar mortality rates (16% and 14%). Mean duration of presenting attack up to onset of toxic megacolon was longer in @entity30 than in @entity31 (62 days versus 31 days) and in unoperated versus operated cases (64 days versus 37 days), but was not significantly different between survivors and mortalities (43 days versus 39 days). Mortality rates were also unaffected by total duration of @entity29 , first attack versus relapse (14% versus 18%), or medical versus surgical therapy (13% versus 17%). Factors which affected mortality included age (30% for @entity1 over 40 years old, versus 5% for those younger than 40), sex (21% in @entity1 versus 13% in @entity1 ), and especially the occurrence of @entity694 (44% for cases with perforation versus only 2% in those without). Of the 12 @entity1 who died, 11 had suffered @entity694 .(ABSTRACT TRUNCATED AT 250 WORDS)

Outcome of @entity137 in ulcerative and XXXX .

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxic dilatation'] @entity66 :: ('MESH:D004194', 'Disease') :: ['overall disease'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease'] @entity1960 :: ('MESH:D003092', 'Disease') :: ['colitis'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colonic perforation'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"]
@entity30 :: (MESH:D003424,Disease) :: ['Crohn's colitis']
