BACKGROUND AND OBJECTIVE:: to evaluate the impact of a solid nutritional supplement on the weight gain of institutionalised older adults >70 years with @entity7493 . The innovation of these high-protein and high-energy cookies was the texture adapted to edentulous @entity1 (Protibis(  ), Solidages, France). DESIGN:: an open, multicentre, randomised controlled trial. SETTING: seven nursing homes. @entity1 : one hundred and seventy-five malnourished older adults, aged 86    8 years. INTERVENTION: all @entity1 received the standard institutional diet. In addition, Intervention group @entity1 received eight cookies daily (11.5 g protein; 244 kcal) for 6 weeks (w0-w6). MEASUREMENTS: five visits (w-4, w0, w6, w10 and w18). Main outcome: percentage of weight gain from w0 to w6 (body mass in kg). Secondary outcomes: appetite, rated using a numerical scale (0: no appetite to 10: extremely good appetite); current episodes of pressure @entity1066 and @entity294 . RESULTS: average weight increased in Intervention group (n = 88) compared with Control group (n = 87) without cookies supplementation (+1.6 versus -0.7%, P = 0.038). @entity1017 persisted 1 month (+3.0 versus -0.2%, P = 0.025) and 3 months after the end of cookies consumption (+3.9 versus -0.9%, P = 0.003), with @entity294 reduction (P = 0.027). There was a synergistic effect with liquid/creamy dietary supplements. Subgroup analysis confirmed the positive impact of cookies supplementation alone on weight increase (P = 0.024), appetite increase (P = 0.009) and pressure @entity1066 reduction (P = 0.031). CONCLUSION: the trial suggested that, to fight against @entity448 , the stimulation of touch (finger food; chewing, even on edentulous gums) and hearing (intra-oral sounds) could be valuable alternatives to sight, smell and taste alterations.

An innovative solid oral nutritional supplement to fight weight loss and XXXX : open, randomised controlled trial of efficacy in institutionalised, malnourished older adults.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'PARTICIPANTS'] @entity7493 :: ('MESH:D011502', 'Disease') :: ['protein-energy malnutrition'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcers'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity448 :: ('MESH:D000855', 'Disease') :: ['anorexia'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['Weight gain']
@entity448 :: (MESH:D000855,Disease) :: ['anorexia']
