BACKGROUND: The influence of bile reflux in the development of @entity420 remains controversial. This was tested in a cohort of @entity1 who had undergone gastrectomy, a procedure often entailed by substantial bile reflux. METHODS: A population-based cohort study of @entity1 who had undergone gastrectomy for peptic @entity1066 in 1964-2008 in Sweden. Follow-up for @entity5 and censoring for death were achieved through linkages to nationwide registries of @entity5 and Population, respectively. The number of observed @entity5 cases in the gastrectomy cohort was divided by the expected number, calculated from the incidence of the entire Swedish population of corresponding age, sex and calendar year. Relative risks were thus presented as standardised incidence ratios with 95% confidence intervals. RESULTS: After exclusion of all @entity1 -years the first year after surgery, the final gastrectomy cohort comprised of 19,767 @entity1 . These @entity1 were followed up for a median of 17 years, and contributed with a total of 348,231 @entity1 -years at risk. The observed number of @entity1 with @entity420 (n=7) was not higher than the expected (n=11.6), providing a standardised incidence ratio of 0.6 (95%CI 0.2-1.2). There were no clear differences between sexes, age groups or latency intervals after gastrectomy. CONCLUSIONS: Gastrectomy for peptic @entity1066 does not appear to increase the risk of @entity420 .

The risk of @entity420 after gastrectomy for peptic XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'person'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer disease'] @entity420 :: ('MESH:D000230', 'Disease') :: ['oesophageal adenocarcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'Cancer']
@entity1066 :: (MESH:D014456,Disease) :: ['ulcer disease']
