AIM: To assess the utility of repetitive nerve stimulation (RNS) in facial and hypothenar muscles in the clinical groups of @entity1737 ( @entity1737 ). @entity1 AND METHODS: We performed RNS study in the orbicularis oculi (O.O.), nasalis and abductor digiti quinti (ADQ) in 115 consecutive @entity8491 @entity1 and classified them according to the classifications of the @entity1737 Foundation of America. @entity1 were classified into three groups: group 1, group 2 (IIa, IIIa and IVa) and group 3 (IIb, IIIb and IVb). RESULTS: RNS was abnormal in 95 @entity1 (82.6%): 78.3% in the O.O., 66.1% in the nasalis and 19.1% in the ADQ. Both facial muscles were statistically more sensitive than the ADQ in all groups of @entity1 . RNS in the O.O. was more frequently abnormal than in the nasalis only in group 1. Sensitivity to @entity934 antibodies in @entity8491 @entity1 was 84%. @entity934 receptor (AChR) and muscle-specific @entity669 kinase antibodies were present in 96.7% of the @entity1 with abnormal RNS in both facial muscles. Single-fiber electromyogram (SFEMG) was abnormal in 91.3% of the tested @entity1 . One of the three tests used for the diagnosis of @entity1737 (AChR antibodies, SFEMG, RNS) was abnormal in 99.1% of the @entity1 . DISCUSSION: O.O. is the most sensitive muscle in all groups of @entity1737 followed by nasalis, while the ADQ is the muscle with the lowest sensitivity. Facial muscles, especially the O.O., should be the first to be tested in @entity1737 . The negativity of all tests (RNS, AChR antibodies, SFEMG) should question the diagnosis of @entity1737 , even in the presence of symptoms consistent with @entity1737 .

Repetitive nerve stimulation of facial and hypothenar muscles: relative sensitivity in different XXXX subgroups.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity1737 :: ('MESH:D009157', 'Disease') :: ['MG', 'myasthenia gravis', 'Myasthenia Gravis'] @entity8491 :: ('MESH:D020294', 'Disease') :: ['myasthenic'] @entity669 :: ('CHEBI:18186', 'Chemical') :: ['tyrosine'] @entity934 :: ('MESH:D000109', 'Chemical') :: ['acetylcholine', 'Acetylcholine']
@entity1737 :: (MESH:D009157,Disease) :: ['myasthenia gravis']
