OBJECTIVE: Very few studies have been conducted in this part of world to identify relation between maternal serum @entity1255 levels and @entity299 in their offsprings. With this perspective in mind, this study was carried out. METHODS: Fifty @entity1 were enrolled in this study. Thirty of these had delivered neonates who were diagnosed to have congenital @entity299 . These were treated as cases. Twenty of these @entity1 had delivered neonates who did not have any congenital @entity299 and were treated as controls. For estimating the levels of plasma @entity1255 , fasting blood samples were taken from the @entity1 in both groups. RESULTS: Out of 30 cases, 14 (46.6%) had a tHcy level more than 15 mol/l and all these @entity1 had delivered babies who were found to have congenital @entity299 . Out of controls, only 3 (15%) had a tHcy level more than 15 mol/l. In babies with @entity1757 , the mean maternal plasma tHcy level was 13.30 mol/l. In babies with Tetralogy of Fallot, the mean maternal plasma tHcy level was 40.07 mol/l. In babies with @entity3886 , the mean maternal plasma tHcy level was 40.93 mol/l. In babies with @entity1145 , the mean maternal plasma tHcy level was 24.89 mol/l. CONCLUSIONS: Increased levels of maternal serum @entity1255 are associated with increased risk of occurrence of @entity4297 in their offsprings, suggesting that maternal @entity3562 is an independent risk factor for @entity4297 .

Maternal @entity3562 and XXXX : A prospective case control study in Indian population.

@entity1 :: ('9606', 'Species') :: ['women'] @entity1255 :: ('MESH:D006710', 'Chemical') :: ['homocysteine'] @entity1145 :: ('MESH:D018785', 'Disease') :: ['Tricuspid atresia'] @entity3886 :: ('MESH:D014188', 'Disease') :: ['Transposition of Great Vessels'] @entity1757 :: ('MESH:D006345', 'Disease') :: ['ventricular septal defects'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart diseases', 'congenital heart disease'] @entity3562 :: ('MESH:D020138', 'Disease') :: ['hyperhomocysteinemia'] @entity4297 :: ('MESH:D006330', 'Disease') :: ['congenital heart defects']
@entity4297 :: (MESH:D006330,Disease) :: ['congenital heart defects']
