OBJECTIVE: To observe the efficacy of a traditional Chinese medicine, Shenzhuo formula, on @entity1 with @entity2316 ( @entity2316 ). METHODS: Eighty-eight outpatients with @entity2316 were enrolled. Changes in estimated glomerular filtration rate (eGFR), @entity1011 clearance, serum @entity1011 , @entity68603 , @entity633 , glycosylated hemoglobin (HbA1C), blood pressure, and lipid profile were measured and analyzed before and after intervention with Shenzhuo formula for 1, 3, 6, 9, 12, and 18 months. RESULTS: Compared with the baseline amounts, serum @entity1011 decreased, and eGFR and @entity1011 clearance increased, significantly after intervention for 1, 3, 6, 9, 12, and 18 months (all P < 0.05). Mean eGFR increased by 2.11 mL/min per 1.73 m  /y after 18-month treatment. Urinary protein at 24 h decreased significantly after 1, 3, 9, and 12 months (P < 0.05). @entity4051 C decreased significantly (P < 0.05) after 3, 6, 9, 12, and 18 months, and systolic blood pressure decreased significantly (P < 0.05) after 1, 3, and 6 months. Total @entity165 decreased significantly (P < 0.05) after 1, 3, 6, and 18 months. @entity412 and low-density lipoprotein- @entity165 decreased significantly (P < 0.05) after 1 and 3 months. CONCLUSION: Shenzhuo formula can improve eGFR and possibly slow @entity2316 progression. Shenzhuo formula can also lower HbA1C, lipid levels and blood pressure.

Efficacy of Shenzhuo formula on XXXX : a retrospective study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4051 :: ('3039', 'Gene') :: ['HbA1'] @entity2316 :: ('MESH:D003928', 'Disease') :: ['DKD', 'diabetic kidney disease'] @entity68603 :: ('D001806', 'Chemical') :: ['blood-urea-nitrogen'] @entity633 :: ('MESH:D000419', 'Disease') :: ['albuminuria'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['Triglyceride'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity2316 :: (MESH:D003928,Disease) :: ['diabetic kidney disease']
