INTRODUCTION: @entity1593 ( @entity1593 ) is an autoimmunological @entity1593 occuring to genetically predisposed individuals. Active @entity1593 is accompanied by presence of multiple antibodies. Anti alpha enolase antibodies were reported in @entity146 like @entity309 , @entity991 . Data about its presence and role in @entity1593 is avaricious. AIM: The aim of this study was to determine presence of anti alpha enolase antibodies in @entity1593 , correlation with gluten exposure, presence of anti tranglutaminase antibodies and Marsh scale. METHODS: Sera from 31 @entity1 with @entity1593 (21 females, 10 males) and 6 healthy subjects were collected. Evaluation of @entity1593 activity and adherence to gluten free diet were obtained by serology tests (presence of endomyslum antibodies and/or anti transglutamineses in IgA or IgG classes) and histological hallmarks. Anti alpha enolase antibodies were identified in sera using ELISA kit. Titres of anti alpha enolase antibodies were identified among @entity1 with newly diagnosed @entity1593 , @entity1593 @entity1 non adhering to gluten free diet (GFD), adhering to GFD and among healthy subjects. RESULTS: Mean titre of anti alpha enolase antibodies was higher in @entity1593 @entity1 (both treated and non treated) in comparison to control group, respectively 1.1 ng/mL, and 0.795 ngl mL. Among @entity1593 @entity1 non adhering to gluten free diet mean titre was 1.4 ng/mL. CONCLUSIONS: Higher anti alpha enolase antibodies titres in non treated @entity1593 suggest usefulness of its measurement. These antibodies might be a novel marker of @entity32 among @entity1593 @entity1 non adhering to GFD.

[Antibodies against alfa-enolase as an indication of inflammatory process in XXXX with celiac disease--preliminary results].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['chronic inflammation'] @entity1593 :: ('MESH:D002446', 'Disease') :: ['Celiac disease', 'CD', 'gluten sensitive enteropathy'] @entity146 :: ('MESH:D001523', 'Disease') :: ['several autoimmunological disorders'] @entity991 :: ('MESH:D015209', 'Disease') :: ['primary sclerosing cholangitis'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis']
@entity1 :: (9606,Species) :: ['patients']
