UNASSIGNED: e19698 Background: Pts with @entity5 frequently suffer from uncontrolled @entity158 . Response rate is an important clinical and quality of care outcome in most guidelines. The primary aim of this study is to determine frequency and predictors associated with @entity158 response to state of the art palliative care. METHODS: Consecutive pts with @entity5 with moderate to severe @entity158 presenting in the Supportive care clinic with a complete Edmonton symptom assessment scale (ESAS) at initial and subsequent visit were reviewed. All pts received interdisciplinary care led by palliative care specialists (IDT) following common care pathways. A logistic regression model to determine if baseline demographics, primary @entity5 type, ESAS, Memorial Delirium assessment scale, and @entity8877 (screening for @entity988 ), were associated with response (defined as >= 2 points reduction in @entity158 intensity). RESULTS: 1150 pts (median age 60; male/female ratio 0.98) were included. Median time between initial and follow-up visit 15 days. The mean (SD), median baseline @entity158 was 6.8 (1.9) and 7. Overall 598/1150 @entity1 (52%) had a response. 411/639 (64%) of pts with @entity158 >= 7/10 (severe @entity158 group) at baseline had response compared to 187/511 (37%) of pts with moderate @entity158 (4-6/10), (p<0.0001), however 217/639(34%) of the severe @entity158 group had @entity158 improved to <=  3/10 (mild @entity158 ) as compared to 170/511(33%) in moderate @entity158 group (p=0.07). Fatigue (r=0.22, p<0.01), @entity308 (r=0.14, <0.01), @entity148 (r=0.16, p<0.01), sleep (r=0.15, p<0.01), and feeling of wellbeing (r=0.14, p<0.01), appetite (r=0.14, p<0.01), @entity390 (r=0.18, p<0.01) are associated with @entity158 at initial consult. Factors associated with response to @entity158 were baseline @entity158 (OR, 1.4 per point; p<0.01), fatigue (OR, 1.01 per point; p=0.014) and ESAS symptom burden (OR, 1.01 per point; p=0.039). However, @entity933 (p=0.50), @entity988 (p=0.19), @entity308 (p=0.35), @entity148 (p=0.25), sleep (p=0.16) did not show significant association with @entity158 response. CONCLUSIONS: Current response criteria have more false positive results in severe @entity158 group. Pts with severe @entity158 needs more frequent and @entity146 IDT. Further studies are warranted.

Frequency and predictors of response to outpatient palliative care in XXXX with moderate to severe @entity5 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8877 :: ('168400', 'Gene') :: ['CAGE'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'advanced cancer'] @entity988 :: ('MESH:D000437', 'Disease') :: ['alcoholism'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity933 :: ('MESH:D003693', 'Disease') :: ['delirium']
@entity1 :: (9606,Species) :: ['patients']
