Insulin-like growth factor II mRNA-binding protein ( @entity21526 ) is an oncofetal protein involved in embryogenesis, which is expressed in a variety of @entity5 . It is rarely expressed in normal adult tissue and @entity5 . The aim of this study was to evaluate the expression of @entity21526 in benign and @entity5 of the ovary. Seventy-nine @entity43 were examined for @entity21526 expression by immunohistochemical analysis, comprising 16 @entity5 , 19 borderline @entity5 . Positive staining was defined as brown staining in the cytoplasm. Negative staining was defined as absent staining or staining of <5% of @entity5 cells. The intensity of staining (weak, moderate, and strong) and percentage (0% to 100%) of neoplastic cells staining positive for cytoplasmic @entity21526 staining were recorded in each case. Moderate to strong cytoplasmic staining for @entity21526 was observed in 30 of 44 (68%) serous @entity189 of the ovary; in contrast, <5% of the borderline and @entity5 expressed @entity21526 ranging from weak to strong cytoplasmic staining. Statistically, the difference in @entity21526 expression between these groups of @entity5 was highly significant (P<0.0001). Our findings demonstrate moderate to strong expression of @entity21526 in the majority of @entity43 as compared with benign/borderline @entity5 , which demonstrated weak to strong expression in a small minority (<5%) of the @entity5 . Thus, @entity21526 may be a useful adjunctive tool in the pathologic evaluation of @entity43 .

XXXX Expression in Serous Tumors of the Ovary.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignant serous tumors', 'benign serous tumors', 'benign tumors', 'serous tumors, and 44 serous carcinomas', 'malignant neoplasms', 'serous tumors', 'tumors'] @entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian tumors', 'ovarian serous carcinomas', 'ovarian serous tumors'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas'] @entity21526 :: ('55272', 'Gene') :: ['IMP3']
@entity21526 :: (55272,Gene) :: ['IMP3']
