This study concerns the effects of @entity1286 in tissues on the rate of development of @entity4058 (Diptera: Calliphoridae) using those tissues as a food source. @entity4058 is a species of @entity238 commonly found on @entity1 corpses in Europe during the early stages of decomposition and thus of forensic interest. Three @entity95 were administered 12.5, 25.0 and 50.0 mg/h of @entity33483 via ear perfusion over a period of 3 h. These dosages and duration of perfusion were calculated to give tissue concentrations of @entity1286 similar to those encountered in fatal @entity1 @entity1445 . A fourth @entity95 was used as a control. Following administration of the drug, @entity95 were sacrificed and 400 eggs of @entity4058 , all of the same age, were placed in the eyes, nostrils and mouth of each @entity95 . Developing larvae were sampled daily to determine growth rate and weight. Puparia and emerging adult flies were also sampled. Data were analyzed using analysis of variance (ANOVA) and Student's T-test. Results of this study show that an underestimation of the postmortem interval of 24 h is possible if the presence of @entity1286 in tissues is not considered. This study demonstrates again the necessity of considering the possible effects of drugs in tissues on insect growth rates when estimating the postmortem interval using entomological techniques.

Effects of @entity1286 in decomposing bodies on the development of XXXX (Diptera: Calliphoridae).

@entity1 :: ('9606', 'Species') :: ['human'] @entity95 :: ('9986', 'Species') :: ['rabbits', 'rabbit'] @entity33483 :: ('CHEBI:55340', 'Chemical') :: ['morphine chlorhydrate'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity1445 :: ('MESH:D062787', 'Disease') :: ['overdoses'] @entity238 :: ('7227', 'Species') :: ['fly'] @entity4058 :: ('13632', 'Species') :: ['Lucilia sericata']
@entity4058 :: (13632,Species) :: ['Lucilia sericata']
