BACKGROUND: There is wide variability in reported locoregional recurrence rates after curative resection of @entity420 of the intraperitoneal colon, and there is no universally accepted surgical technique regarding length of the resected specimen or extent of lymphadenectomy. The aim of this study was to determine the disease-free survival, locoregional failure, and perioperative morbidity of @entity1 undergoing curative resection of @entity694 . STUDY DESIGN: The records of 316 consecutive @entity1 undergoing curative resection for primary @entity420 of the intraperitoneal colon between 1990 and 1995 were reviewed. Locoregional recurrence was defined as disease at the @entity254 or in the adjacent mesentery, peritoneum, retroperitoneum, or @entity189 . The product-limit method (Kaplan-Meier) was used to analyze survival and @entity5 recurrence. RESULTS: The study population comprised 167 @entity1 and 149 @entity1 , mean age 70+/-12 years (range 22 to 95 years). Median followup was 63+/-25 months. Five-year disease-free survival was 84% overall. Disease-free survival @entity5 stage: stage I, 99% (n = 73); stage II, 87% (n = 151); stage III, 72% (n = 92). The predominant pattern of @entity5 recurrence was distant failure only. Overall locoregional recurrence (locoregional and locoregional plus distant) at 5 years was 4%. Locoregional recurrence @entity5 stage: stage I, 0%; stage II, 2%; stage III, 10%. Of the 12 @entity1 who suffered locoregional recurrence, 9 (75%) had T4 @entity5 , @entity66 , or both. Major and minor complications occurred in 93 @entity1 (29%) including: @entity834 or intraabdominal abscess (n = 4, 1%); @entity548 (n = 8, 3%); @entity299 (n= 17, 5%); @entity1151 (n=4, 10%); @entity204 (n=2, 1%). Multivariate analysis (Cox proportional hazards) revealed that the only independent predictor of disease-free survival and locoregional control was @entity5 stage. CONCLUSION: Longterm survival and locoregional control can be achieved for @entity1 with @entity694 , with low morbidity. In the absence of adjacent organ invasion and @entity66 , locoregional recurrence should be a rare event. Just as for @entity5 , the technical aspects of colectomy for @entity694 deserve renewed attention.

Locoregional recurrence and survival after curative resection of XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity834 :: ('MESH:D057868', 'Disease') :: ['anastomotic leak'] @entity66 :: ('MESH:D004194', 'Disease') :: ['N2 nodal disease'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'paralleled tumor', 'primary tumors', 'rectal cancer'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomatosis'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['pulmonary embolism'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac complications'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon adenocarcinoma', 'colon cancer'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity694 :: (MESH:D003110,Disease) :: ['adenocarcinoma of the colon']
