BACKGROUND: The ventrolateral thalamus (ventral intermediate nucleus [ @entity2277 ]) is the traditional target for neurosurgical treatment of essential @entity400 . The target, however, has varied substantially among different neurosurgeons. OBJECTIVE: To evaluate the effect of deep brain stimulation in the thalamus and posterior subthalamic area (PSA) in relation to electrode location. METHODS: Thirty-six (17 @entity2277 /19 PSA) @entity1 with 44 deep brain stimulation electrodes were included in this retrospective study. The effect of stimulation was evaluated with standardized settings for each contact using items from the Essential Tremor Rating Scale. RESULTS: When each contact was evaluated in terms of the treated hand with standardized stimulation, the electrode contact providing the best effect in the individual @entity1 was located in the zona incerta or radiation prelemniscalis in 54% and the @entity2277 in 12%. Forty contacts provided a @entity400 reduction of > 90%. Of these, 43% were located in the PSA and 18% in the @entity2277 according to the Schaltenbrand atlas. Of these 40 contacts, 37 were found in the PSA group. CONCLUSION: More contacts yielding an optimal effect were found in the PSA group than in the @entity2277 . Many @entity1 operated on in the @entity2277 got the best effect from a contact located in the PSA. This might suggest that the PSA is a more efficient target than the @entity2277 .

Thalamic and subthalamic deep brain stimulation for essential XXXX : where is the optimal target?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity2277 :: ('7431', 'Gene') :: ['Vim']
@entity400 :: (MESH:D014202,Disease) :: ['tremor']
