@entity715 is a common pathology underlying @entity299 , @entity1211 ( @entity1211 ). The Global Burden of Disease Study 2010 (GBD 2010) documented that @entity299 and @entity64 collectively caused one in four @entity204 worldwide. GBD 2010 did not report data for @entity1211 as a cause of @entity204 and disability. We performed a systematic review of the literature on the global disease burden due to @entity1211 in low, middle and high income countries. Studies from Western Europe, North America, Australia, and Southern Latin America (Argentina) yielded consistent results with annual incidences ranging from 0.75 to 2.69 per 1,000 individuals in the population. The incidence increased to between 2 and 7 per 1,000 among those 70 years of age or more. Although the incidence is lower in individuals of Chinese and Korean ethnicity, their disease burden is not low because of population aging. @entity1211 associated with hospitalisation was the leading cause of disability-adjusted-life-years (DALYs) lost in low and middle income countries, and second in high income countries, responsible for more DALYs lost than @entity55 , @entity1212 , and adverse drug events. @entity1211 causes a major @entity66 across low, middle, and high income countries. More detailed data on the global burden of @entity1211 should be obtained to inform policy and resource allocation in health systems, and to evaluate if improved utilisation of preventive measures will reduce the burden.

XXXX : A major contributor to global disease burden.

@entity1212 :: ('MESH:D055499', 'Disease') :: ['catheter-related blood stream infections'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity66 :: ('MESH:D004194', 'Disease') :: ['burden of disease'] @entity55 :: ('MESH:D011014', 'Disease') :: ['nosocomial pneumonia'] @entity299 :: ('MESH:D006331', 'Disease') :: ['ischaemic heart disease'] @entity715 :: ('MESH:D013927', 'Disease') :: ['Thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['ischaemic stroke, and venous thromboembolism', 'VTE'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'deaths']
@entity715 :: (MESH:D013927,Disease) :: ['Thrombosis']
