@entity162 presents particular challenges with regard to assessing response to therapy. Criteria for determining remission and recovery have been suggested for @entity1316 , but the clinical usefulness of these terms in @entity162 is elusive. Formal psychological rating scales may be impractical in a routine medical practice setting. As an alternative, clinicians might probe for information about particular "signal events," such as @entity25 , that may herald mood fluctuations. The ultimate goal of bipolar management should be complete and sustained remission, whenever possible, although most @entity1 will not achieve this status for any significant length of time. Furthermore, overaggressive management might entail pushing medication doses to intolerable levels. Individual treatment goals should always take into account @entity1 acceptance of side effect burden, allowing for trade-offs between treatment effect and quality of life. Noncompliance with therapy, notoriously common among @entity1 suffering from @entity162 , can stem from @entity137 , treatment ineffectiveness, or even treatment success if the @entity1 misses the @entity162 . Despite effective treatment, relapse is common. Realistic treatment goals should strive for sustained symptom abatement while maximizing @entity1 quality of life from visit to visit.

Response, remission, and XXXX : what are the realistic treatment goals?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity162 :: ('MESH:D001714', 'Disease') :: ['bipolar disorder', 'manic symptoms', 'Bipolar disorder'] @entity137 :: ('MESH:D064420', 'Disease') :: ['drug side effects'] @entity1316 :: ('MESH:D019964', 'Disease') :: ['mood disorders'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep disturbances']
@entity162 :: (MESH:D001714,Disease) :: ['recovery in bipolar disorders']
