BACKGROUND: Arteriovenous shunt in the @entity35 is an extremely useful experimental animal model for investigating @entity1283 as well as the hemodynamics and endocrine aspects of @entity712 . AIMS: The present study was to develop 2 pre-tricuspid and 1 post-tricuspid models of @entity2758 to induce @entity8158 and increase pulmonary blood flow in growing @entity35 . METHODS: In the first model, an @entity2758 was created from the common iliac artery to the inferior vena cava (ICS). The second model was shunted from the common carotid artery to the external jugular vein (CJS). A post-tricuspid shunt (the third model) was made by introducing the right common carotid artery into the right ventricular outflow tract (CVS). RESULTS: Four weeks after the shunt surgery, the pulmonary artery pressure was 14.4 +/- 0.5 mmHg in the control group, 15.8 +/- 0.8 mmHg in the ICS group, 21.2 +/- 0.7 mmHg in the CJS group, and 20.2 +/- 1.1 mmHg in the CVS group. The percentage of increasing pulmonary blood flow was 33.0 +/- 1.0% in the CJS group and 26.9 +/- 1.3% in the ICS group four weeks after shunt operation. The @entity26 partial pressure of pulmonary artery blood was 30.9 +/- 0.7 mmHg in the control group, 33.6 +/- 1.0 mmHg in the ICS group, 43.7 +/- 1.4 mmHg in the CJS group and 41.1 +/- 2.5 mmHg in the CVS group. The CJS and CVS groups had significant right ventricle @entity1184 . CONCLUSIONS: These three models can provide for study of the flow-pressure effect of the right heart and pulmonary circulation.

Simple methods to elevate pulmonary arterial pressure by pre- and post-tricuspid shunts in XXXX .

@entity712 :: ('MESH:D006333', 'Disease') :: ['chronic heart failure'] @entity2758 :: ('MESH:D001165', 'Disease') :: ['arteriovenous shunt'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['hypertrophy'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['cardiac hypertrophy'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity8158 :: ('MESH:D017380', 'Disease') :: ['right ventricular hypertrophy'] @entity35 :: ('10116', 'Species') :: ['rat', 'rats']
@entity35 :: (10116,Species) :: ['rats']
