OBJECTIVES: To report the initial clinical experience with a novel @entity118 ( @entity118 ) closure device, the GORE(  ) CARDIOFORM @entity118 Occluder (GCO). BACKGROUND: Transcatheter closure has become the treatment of choice for secundum @entity118 . A wide range of occluder devices are available, but concern has been raised about the risk of @entity299 associated with rigid devices and future access to the left atrium METHODS: Retrospective chart review of @entity1 treated with the GCO at three Canadian centers. Primary outcomes were procedural success and residual shunting at follow-up, as well as 30-day major adverse events. Secondary outcomes included new onset @entity943 , @entity174 ( @entity174 ), and all cause mortality. Clinical, echocardiographic, procedural data, and follow-up outcome variables were collected in each participating hospital. RESULTS: Between February and December 2015, 26 @entity1 (5 @entity1 and 21 adults) underwent transcatheter @entity118 closure with the GCO and were included in the study cohort. Procedural success was achieved in 22 of 26 @entity1 (85%) and no major procedural complications were observed. Two @entity1 (8%) presented new onset @entity4710 during early follow-up (0-30 days). Follow-up echocardiography (median of 119 days [IQR: 92-146]) demonstrated no residual shunt in all implanted @entity1 . After a median clinical follow-up of 174 days (IQR: 135-239), one @entity1 died of an unrelated cause, there were no documented major adverse cardiovascular events. Fluoroscopic imaging of the device was performed in 20 @entity1 (91%), and @entity174 was noted in five cases. No clinical consequence or device dysfunction was observed in these @entity1 . CONCLUSIONS: In this first-in- @entity1 multicenter study, the GCO was safe and effective for @entity118 closure, with no major adverse events or residual shunt at follow-up.    2017 Wiley Periodicals, Inc.

Initial clinical experience with the GORE(  ) CARDIOFORM XXXX occluder for transcatheter @entity118 closure.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient', 'man'] @entity4710 :: ('MESH:D013617', 'Disease') :: ['atrial tachyarrhythmia'] @entity174 :: ('MESH:D050723', 'Disease') :: ['wire frame fractures', 'WFF'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac erosion'] @entity118 :: ('MESH:D006344', 'Disease') :: ['atrial septal defect', 'ASD'] @entity943 :: ('MESH:D001145', 'Disease') :: ['atrial arrhythmias']
@entity118 :: (MESH:D006344,Disease) :: ['ASD']
