INTRODUCTION: @entity5 ( @entity5 ) are the leading cause of late death among liver transplant recipients with an incidence of 5% to 15%, which is significantly greater than the general population. In this retrospective study, we compared this complication in liver transplant recipients to sex- and age-matched controls. @entity1 : Among 410 @entity1 who received liver allografts between March 1986 and December 2000, 32 (7.8%) developed a @entity18961 . @entity5 were the most frequent histologic lineage. A complete response was observed in 19 @entity1 (59.4%), a partial response in eight (25%), and no response in five (15%). Survival was lower among liver transplant recipients than controls, a difference that was statistically significant. Treatment consisted of surgery in 76.7%, radiotherapy in 16.7%, chemotherapy in 13.3%, and reduction of immunosuppression in 10%. RESULTS: The mean survival time in transplant @entity1 of 122.97 months (95% CI; range 98-147 months) was significantly shorter than controls, 156.5 months (95% CI; range 141-171 months). About 50% of @entity1 were smokers (active or ex-smokers), compared to 20.7% of controls (P=.049). Significant differences were also found when the three subgroups (smokers, previous smokers, and nonsmokers) were analyzed separately (P=.013). @entity1 were smokers (active or nonactive) among 45% of cases of @entity1489 ; 60% of @entity5 ; 71.4% of epidermoids; and 33% of @entity242 . CONCLUSIONS: @entity5 , a complication of long-term immunosuppression in @entity1 after liver transplantation, most frequently presented as @entity1489 and PTLD. Occurrence of a @entity18961 was an adverse prognostic factor for survival. Smoking represents an independent risk factor for these @entity5 .

De novo XXXX and liver transplantation.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Epidermoid tumors', 'hematological tumors', 'DNTs', 'De novo tumors', 'tumors'] @entity1489 :: ('MESH:D012878', 'Disease') :: ['skin tumors'] @entity18961 :: ('30833', 'Gene') :: ['DNT']
@entity5 :: (MESH:D009369,Disease) :: ['malignancies']
