PURPOSE: According to current treatment guidelines, surgical @entity157 ( @entity157 ) is mostly restricted to a limited subgroup of @entity1 . Due to improved surgical techniques and perioperative management, liver resections may also be performed more extendedly and also in cirrhotic livers with clinical signs of @entity101 in selected @entity1 . In this study, the clinical and long-term outcomes of liver resection in @entity157 @entity1 with or without @entity1575 were evaluated. METHODS: One hundred fifty-eight @entity1 undergoing liver resection for primary @entity157 at our institution were identified. Logistic and Cox regression analyses were used to identify prognostic parameters for @entity260 and survival. RESULTS: In our cohort of @entity1 , there was no association between clinical parameters or extent of surgical resection and postoperative morbidity. Only @entity96 ( @entity96 ) stage C @entity1 were at significantly higher risk for major complications (OR 5.27, P   =   0.009). Risk factors influencing long-term survival were @entity1 age (HR 1.026, P   =   0.027) and @entity96 stage C (HR 3.47, P   =   0.002). Compared to @entity1 without @entity1575 , @entity96 stage A and B @entity1 undergoing resection were at similar risk for the development of severe complications and long-term mortality. CONCLUSION: Liver resection as potentially curative therapy can be performed in selected @entity1 in @entity96 stage B, as well as in @entity1 with clinical signs of @entity101 . The resection of @entity157 -classified @entity96 stage C is feasible but associated with significant morbidity and mortality.

Morbidity of hepatic resection for intermediate and advanced XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity101 :: ('MESH:D006973', 'Disease') :: ['portal hypertension'] @entity96 :: ('MESH:D008113', 'Disease') :: ['Barcelona Clinic Liver Cancer', 'BCLC'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['liver cirrhosis'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'resection of hepatocellular carcinoma']
@entity157 :: (MESH:D006528,Disease) :: ['hepatocellular carcinoma']
