OBJECTIVE: To evaluate the characteristics of @entity259 cases treated at a reference hospital for @entity5 between 2008 and 2010. METHODS: we studied 807 cases and analyzed the following clinicopathologic variables: symptoms, risk factors, diagnostic tests, staging, histological type, treatment performed and complications. RESULTS: Females were more affected, with 660 cases (82%). The average age at diagnosis was 44.5 years. Prior exposure to ionizing @entity1161 was reported by 22 (3%) @entity1 , a family history of @entity259 by 89 (11%), and 289 (36%) individuals reported other types of @entity5 in the family. The fine needle aspiration biopsy was the main parameter for surgical indication and was suggestive of @entity189 in 463 @entity1 (57%). @entity1377 was the most common histological type, with 780 cases (96.6%). There were 728 (90%) total thyroidectomies, 43 (5.3%) reoperations or partial thyroidectomies followed by totalization, 23 (2.8%) extended thyroidectomies and only 13 (1.6%) partial thyroidectomies (lobectomy with isthmectomy). Neck dissection associated with thyroidectomy was done in 158 @entity1 (19.5%). We observed a predominance of @entity5 classified as T1 in 602 (74.6%) @entity1 . Transient @entity3747 was the most frequent complication. CONCLUSION: The results show that the worldwide increase in the incidence of @entity259 has changed the profile of @entity1 seen at a referral service. In addition, there were changes in the type of surgical treatment used, with increased use of total thyroidectomy in relation to partial and subtotal ones, and decreased use of elective neck dissections.

Evolution in the profile of XXXX cases treated in an oncology reference service: what changed in the last 20 years.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1377 :: ('MESH:D002291', 'Disease') :: ['Papillary carcinoma'] @entity3747 :: ('MESH:D006996', 'Disease') :: ['hypocalcemia'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'tumors'] @entity1161 :: ('MESH:D011832', 'Disease') :: ['radiation'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity259 :: ('MESH:D013964', 'Disease') :: ['thyroid cancer', 'thyroid carcinoma']
@entity259 :: (MESH:D013964,Disease) :: ['thyroid cancer']
