PURPOSE: The aim of this retrospective study was to evaluate @entity231 incidence in a homogeneously-treated group of @entity1 after @entity348 ( @entity348 ) followed by autologous bone marrow transplantation or peripheral blood stem cell transplantation. METHODS AND MATERIALS: Between 1982 and 1994, a total of 260 @entity1 received either autologous bone marrow or blood stem cell transplantation for @entity1583 at the University of Heidelberg. Two hundred nine of these @entity1 received @entity348 in our hospital. Radiotherapy was applied as hyperfractionated @entity348 , with a median dose of 14.4 Gy in 12 fractions over 4 days. Minimum time between fractions was 4 h. Photons with an energy of 23 MeV were used with a dose rate of 7-18 cGy/min. Ninety-six of the 209 irradiated @entity1 were still alive in 1996; 86 of these @entity1 (52 @entity1 , 33 @entity1 ) answered a questionnaire and could be examined ophthalmologically. The median age at time of @entity348 was 38.5 years, with a range of 15-59 years. RESULTS: The median follow-up is now 5.8 years, with a range of 1.7-13 years. @entity231 occurred in 28/85 @entity1 (32.9%) after a median of 47 months (1-104 months). In 6 of 28 @entity1 who developed a @entity231 , surgery of the @entity231 was performed. Whole-brain irradiation prior to @entity348 had been performed more often in the group of @entity1 developing @entity231 (14.3%) versus 10.7% in the group of @entity1 without @entity231 . However, there was no statistical difference (Chi-square, p>0.05). CONCLUSION: @entity231 is a common side effect of @entity348 . @entity231 incidence found in our @entity1 is comparable to results of other centers using a fractionated regimen for @entity348 . To assess the incidence of @entity231 after @entity348 , a long-term follow-up is required.

@entity231 incidence after XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity348 :: ('MESH:C535338', 'Disease') :: ['total-body irradiation', 'TBI'] @entity1583 :: ('MESH:D019337', 'Disease') :: ['hematological malignancy'] @entity231 :: ('MESH:D002386', 'Disease') :: ['Cataract', 'cataract']
@entity348 :: (MESH:C535338,Disease) :: ['total-body irradiation']
