OBJECTIVES: Previously preeclamptic @entity1 may express @entity73 , which have largely been unappreciated or attributed to stresses of a complicated pregnancy. This study aimed to explore the scope of perceived neurocognitive and psychosocial problems as well as quality of @entity1468 . STUDY DESIGN: Observational study. Through website promotion and e-mail, registrants of the USA-based Preeclampsia Foundation who experienced @entity1468 in the past 20years were invited to complete a web-based survey. @entity1 were requested to ask an acquaintance that had a normotensive pregnancy to also complete the survey (controls). MAIN OUTCOME MEASURES: The Cognitive Failures Questionnaire (CFQ), abbreviated WHO Quality Of Life questionnaire (WHOQOL-BREF), Social Functioning Questionnaire (SFQ) and Breslau Short Screening Scale for DSM-IV @entity1005 were used in the survey. Analysis was performed using Mann-Whitney U tests and linear regression. RESULTS: 966 cases and 342 controls completed the survey (median age 34, median time since first pregnancy 4 vs. 5years). Cases scored significantly worse on CFQ (median 35 vs. 27), WHOQOL-BREF domains physical health (15 vs. 17), psychological (13 vs. 15), social relationships (13 vs. 15) and environment (15 vs. 16), and SFQ (8 vs. 7). All p<0.001. Multivariable analysis showed an independent significant effect of @entity3036 on CFQ and of @entity2704 on all questionnaires and the effect of @entity1468 was still present after adjustment for confounders. Posttraumatic stress symptoms accounted for part of the relationships. CONCLUSIONS: Previously preeclamptic @entity1 appear to perceive more cognitive and social problems, and report poorer quality of life compared to a group of @entity1 with normotensive pregnancies. Research relating to the origin and management of these issues is needed.

The brain study: Cognition, quality of life and social functioning following XXXX ; An observational study.

@entity1 :: ('9606', 'Species') :: ['women', 'Participants'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive difficulties'] @entity1005 :: ('MESH:D013313', 'Disease') :: ['Posttraumatic Stress Disorder'] @entity2704 :: ('MESH:D008881', 'Disease') :: ['migraine'] @entity3036 :: ('MESH:D004461', 'Disease') :: ['eclampsia'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['life following preeclampsia', 'preeclampsia']
@entity1468 :: (MESH:D011225,Disease) :: ['preeclampsia']
