BACKGROUND: The impact of wiping in laser skin resurfacing has not been systematically studied. METHODS: We examined the effects of wiping during single- and multiple-pass high energy pulsed @entity515 laser skin resurfacing in a farm @entity1707 . Consequences of wiping were evaluated with regard to depth of residual thermal damage, tissue @entity39 , and @entity3385 . Also, the impact of wiping on gross wound healing was observed. Wounds were followed for 21 days and biopsies were obtained on postoperative days 0, 1, and 21. RESULTS: Immediate postoperative biopsies of single-pass wounds showed equivalent residual thermal damage regardless of wiping; in contrast, biopsies from multiple-pass sites without wiping showed more extensive and variable residual thermal damage than wiped sites. On postoperative day one, single pass sites without wiping were grossly less erythematous than wiped sites, and biopsies showed less extensive @entity39 and @entity32 . In contrast, multiple pass sites without wiping were grossly more erythematous than corresponding wiped sites, and biopsies revealed significantly increased and variable @entity39 . After 21 days, multiple pass sites without wiping were grossly more erythematous and showed a thicker band of @entity3385 microscopy. CONCLUSIONS: For single pass wounds, not wiping decreased the level of wounding. In contrast, not wiping in multiple pass wounds significantly increased the depth and variability of residual thermal damage and @entity39 , resulting in prolonged healing.

The effect of wiping on skin resurfacing in a @entity1707 model using a high energy pulsed XXXX laser system.

@entity1707 :: ('9823', 'Species') :: ['pig'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity515 :: ('CHEBI:29334', 'Chemical') :: ['CO2'] @entity3385 :: ('MESH:D012178', 'Disease') :: ['fibroplasia']
@entity515 :: (CHEBI:29334,Chemical) :: ['CO2']
