UNASSIGNED: @entity1 skin allografts are one of the best temporary biological coverings for severely burned @entity1 . Cryopreserved ( @entity15082 ) and @entity653 -preserved (GPA) allografts are the most widely used types. This study compared the allograft efficiency of both preservation methods under the same conditions. To simulate actual clinical conditions, we used a porcine wound model. In addition, we evaluated the macroscopic and microscopic scoring of graft performance for each method. Porcine cadaver skin 1  mm thick was obtained from one @entity1707 . Cryopreserved skin cell viability was 20.8  %, @entity653 -preserved skin was 9.08  %, and fresh skin was 58.6  %. We made ten partial-thickness wounds each in two @entity1707 . The take rates on day 2 were 96.23 and 82.65  % in the GPA and @entity15082 group (both n  =  9), respectively. After 1  week, the take rates of both groups were nearly equal. The removal rate at week 5 was 98.87 and 94.41  % in the GPA and @entity15082 group, respectively. On microscopic findings at week 2, @entity32 was greater in the @entity15082 group. Other findings such as fibroblast @entity1373 and neovascularization were not significantly different between both groups. At week 5, the score of collagen fiber synthesis was 2.67      0.47 and 2.33      0.47 in the GPA and @entity15082 group, respectively. The epidermal-dermal junction was 2.22      0.79 and 2.00      0.47 in the GPA and @entity15082 group, respectively. These findings suggest that wound healing takes longer in the @entity15082 group. The preservation method of allografts is not a absolute factor in the wound healing process in this wound model.

Comparison between cryopreserved and XXXX -preserved allografts in a partial-thickness porcine wound model.

@entity1 :: ('9606', 'Species') :: ['patients', 'Human'] @entity1707 :: ('9823', 'Species') :: ['pigs', 'pig'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['hyperplasia'] @entity653 :: ('MESH:D005990', 'Chemical') :: ['glycerol'] @entity15082 :: ('C048599', 'Chemical') :: ['CPA']
@entity653 :: (MESH:D005990,Chemical) :: ['glycerol']
