Exercise can have anti-inflammatory effects in @entity28 , but the optimal @entity164 and intensity of exercise are not clear. This study compared short-term @entity2101 ( @entity2101 ) with moderate-intensity continuous training (MICT) in terms of improvement in @entity410 , markers of @entity32 , and @entity413 control in previously inactive adults at elevated risk of developing @entity164 2 @entity6 . Thirty-nine inactive, overweight/obese adults (32 @entity1 ) were randomly assigned to 10 sessions over 2 wk of progressive @entity2101 (n = 20, four to ten 1-min sessions at    90% peak heart rate, 1-min rest periods) or MICT (n = 19, 20-50 min at    65% peak heart rate). Before and 3 days after training, @entity1 performed a peak @entity3612 uptake test, and fasting blood samples were obtained. Both @entity2101 (1.8    0.4 vs. 1.9    0.4 l/min, pre vs. post) and MICT (1.8    0.5 vs. 1.9    0.5 l/min, pre vs. post) improved peak @entity3612 uptake (P < 0.001) and lowered plasma @entity9208 (P < 0.05). @entity2939 ( @entity2939 ) expression was reduced on lymphocytes and monocytes after both @entity2101 and MICT (P < 0.05) and on neutrophils after MICT (P < 0.01). @entity2938 on lymphocytes was reduced after @entity2101 and MICT (P < 0.05). Plasma inflammatory cytokines were unchanged after training in both groups, but MICT led to a reduction in fasting plasma @entity413 (P < 0.05, 5.9    1.0 vs. 5.6    1.0 mmol/l, pre vs. post). Ten days of either @entity2101 or MICT can improve @entity410 and @entity413 control and lead to reductions in @entity2938 and @entity2939 expression. MICT, which involved a longer duration of exercise, may be superior for reducing fasting @entity413 .

Short-term high-intensity interval and moderate-intensity continuous training reduce leukocyte @entity2939 in inactive adults at elevated risk of @entity164 2 XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity410 :: ('MESH:D012640', 'Disease') :: ['cardiorespiratory fitness'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity9208 :: ('MESH:D019270', 'Chemical') :: ['fructosamine'] @entity2938 :: ('7097', 'Gene') :: ['TLR2'] @entity2101 :: ('MESH:C538394', 'Disease') :: ['HIIT', 'high-intensity interval training'] @entity164 :: ('MESH:D017827', 'Disease') :: ['type'] @entity3612 :: ('D013481', 'Chemical') :: ['O2'] @entity2939 :: ('7099', 'Gene') :: ['TLR4', 'Toll-like receptor (TLR) 4'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes']
