BACKGROUND: In @entity1 with more complex @entity1713 ( @entity1713 ) not complicated by proliferative @entity1715 (PVR), the most appropriate operating method is controversial, and different surgeons use different techniques. The Scleral Buckling Versus Primary Vitrectomy in Rhegmatogenous @entity1713 Study ( @entity29552 Study) is designed to compare primary vitrectomy and scleral buckling techniques in these @entity1 . METHODS: The @entity29552 Study is a multicentre, randomised, controlled clinical trial stratified by lens status. @entity1 with @entity1713 which is not complicated by PVR grade B or C and which cannot be treated with a single meridional sponge are randomised to either scleral buckling or pars plana vitrectomy as first surgical intervention. Four hundred consecutive @entity1 are to be recruited per subtrial (phakic and aphakic/pseudophakic @entity1 ), and followed up for 1 year. The primary endpoint (functional outcome) is the change in visual acuity. Secondary endpoints (anatomical outcome) include @entity86 , retinal reattachment and the number of reoperations necessary to achieve retinal reattachment. Twenty-seven institutions (49 surgeons) in six European countries have been recruited for participation in the study. CONCLUSION: The @entity29552 Study is the first randomised prospective clinical trial to compare scleral buckling and primary vitrectomy in @entity1 with @entity1713 . The results of this study should enable vitreoretinal surgeons to improve the surgical therapy of @entity1 with the more complicated manifestations of @entity1713 .

Scleral buckling versus primary vitrectomy in @entity1713 ( @entity29552 Study): design issues and implications. XXXX Study report no. 1.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1715 :: ('MESH:D018630', 'Disease') :: ['vitreoretinopathy'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['rhegmatogenous retinal detachments', 'RRD', 'Retinal Detachments'] @entity29552 :: ('6697', 'Gene') :: ['SPR'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative PVR']
@entity29552 :: (6697,Gene) :: ['SPR']
