The results of a case series of 51 consecutively treated, @entity737 implants in 38 @entity1 with follow-up measurements from 3 to 7.5 years are presented. Each implant displayed @entity548 on probing, probing depths >=  6 mm, and @entity604 >=  4 mm prior to surgery. A successful regenerative approach including surface decontamination, use of enamel matrix derivative, a combination of platelet-derived growth factor with anorganic @entity291 bone or mineralized freeze-dried bone, and coverage with a collagen membrane or a subepithelial connective tissue graft was employed in all cases. @entity1 were divided into two groups. Group 1 included @entity1 in which the greatest defect depth was visible on radiographs; group 2 included @entity1 in which the greatest loss of bone was on the facial or oral aspect of the implant. Bone level changes in @entity1 in group 2 were determined by probe sounding under local anesthesia. Probing depth reductions at 3 to 7.5 years of follow-up were 5.4 and 5.1 mm in groups 1 and 2, respectively. Concomitant bone level gain was 3.75 mm in group 1 and 3.0 mm in group 2. No implant in either group lost bone throughout the duration of the study. The results to date with this regenerative approach for the treatment of @entity737 appear to be encouraging.

Successful management of XXXX with a regenerative approach: a consecutive series of 51 treated implants with 3- to 7.5-year follow-up.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity604 :: ('MESH:D016301', 'Disease') :: ['bone loss'] @entity737 :: ('MESH:D057873', 'Disease') :: ['peri-implantitis-affected', 'peri-implantitis'] @entity291 :: ('9913', 'Species') :: ['bovine']
@entity737 :: (MESH:D057873,Disease) :: ['peri-implantitis']
