BACKGROUND: Wound healing is a complex process leading to regeneration of damaged skin tissue. Arnebia euchroma (AE) have many effective activities such as anti-inflammatory, antimicrobial, antioxidative, and anti-tumoral effects. The extract of AE has positive effects on burn wounds. This study is designed to investigate the healing effects of AE on excisional wounds in @entity35 . MATERIALS AND METHODS: Thirty six @entity35 with the age of 8 weeks divided into three groups. One group (E1) was treated with AE gel at a concentration of 10%. Control group (C1) received normal saline and the vehicle group (C2) was treated with @entity5070 cellulose gel as the vehicle for 14 days. Stereological analysis was done to investigate the collagen bundle and hair follicale synthesis, vascularization, fibroblast proliferation. Pathological evaluation was also conducted. RESULTS: In this study, pathological evaluation showed severe acute @entity32 in C2 group, chronic and acute @entity32 in C1 and also more wound contraction in E1 in comparison with other groups. There was a meaningful difference between E1 and C1 regarding fibroblast proliferation (P < 0.05). CONCLUSION: Results of this study revealed the healing effect of AE on excisional wounds and recommend its administration after further clinical investigations.

Wound Healing Effect of Arnebia euchroma gel on Excisional Wounds in XXXX .

@entity35 :: ('10116', 'Species') :: ['rats'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity5070 :: ('CHEBI:41402', 'Chemical') :: ['carboxymethyl']
@entity35 :: (10116,Species) :: ['Rats']
