Objective. This systematic review aimed to assess current evidence from randomized controlled trials (RCTs) on the effects of acupuncture for @entity1 with @entity11157 ( @entity11157 ). Methods. We searched twelve databases to identify relevant studies published before July 2014. The outcomes were serum follicle-stimulating hormone (FSH) levels and resumption of menstruation. Two reviewers independently assessed the risk of bias using the Cochrane's tool, extracted the results, and evaluated the overall level of the evidence using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. Results. Eight RCTs were selected. Acupuncture significantly lowered serum FSH levels and more @entity1 receiving acupuncture reported resumption of menses. However, the results should be interpreted with caution due to a small number of @entity1 , high risk of bias for blinding, and likely publication bias. The level of evidence for FSH level and resumption of menses were assessed as "low" using GRADE. Conclusion. The current evidence on acupuncture for @entity11157 is insufficient to draw a firm conclusion due to scarcity of studies with a low risk of bias and likely publication bias. Further rigorously designed and conducted studies are needed to confirm the effectiveness and safety of acupuncture in @entity1 with @entity11157 .

Effectiveness of Acupuncture for XXXX : A Systematic Review and Meta-Analysis.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients'] @entity11157 :: ('MESH:D016649', 'Disease') :: ['POI', 'primary ovarian insufficiency']
@entity11157 :: (MESH:D016649,Disease) :: ['Primary Ovarian Insufficiency']
