OBJECTIVE: To carry out a prospective evaluation of @entity927 ( @entity928 ) use in @entity130 @entity1 . @entity1 AND METHODS: @entity928 was introduced to all emergency ambulances and emergency departments in the South West, UK, on 1 December 2011. We carried out a prospective evaluation of @entity928 use in @entity130 @entity1 in the South West Peninsula between December 2011 and December 2012. We collected prehospital and hospital data on @entity928 administration using the Trauma Audit Research Network database. Data on prehospital administration of @entity928 were cross-checked with the South Western Ambulance Service Trust. Data were analysed using SPSS (version 20). RESULTS: Altogether, 82 @entity1 were administered @entity928 during the study period. The median age of the @entity1 was 49 years (IQR 30, 66), and 72% were @entity1 . One-third of the @entity1 arrived at hospital by air ambulance. During the first 3 months, administration of @entity928 was limited to one @entity1 each month receiving the drug. However, an upward trend was observed after June until October 2012, with the increment being more than 10 fold in July, September and October 2012. CONCLUSION: This is the first study to evaluate the use of @entity928 in civilian practice in the UK. Our study shows that ambulance service personnel and emergency departments can effectively administer @entity928 .

@entity927 in major XXXX : implementation and evaluation across South West England.

@entity130 :: ('MESH:D014947', 'Disease') :: ['trauma'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS', 'men'] @entity928 :: ('CHEBI:36088', 'Chemical') :: ['TXA'] @entity927 :: ('MESH:D014148', 'Chemical') :: ['tranexamic acid']
@entity130 :: (MESH:D014947,Disease) :: ['trauma']
