OBJECTIVE: To evaluate the effects of environmental @entity286 smoke (ETS) on perinatal outcomes. DESIGN: Retrospective cohort study. SETTING: Newfoundland and Labrador, Canada. POPULATION: Nonsmoking @entity1 with singleton gestations who delivered 1 April 2001-31 March 2009, identified through the Newfoundland and Labrador Provincial Perinatal Database. METHODS: @entity1 who self-reported exposure to ETS were compared with those who reported no exposure. Univariate analyses and multivariate linear and logistic regression analyses (adjusting for maternal age, parity, partnered status, work status, level of education, body mass index, @entity167 use, illicit drug use and gestational age) were performed and odds ratios(OR; or adjusted differences) with 95% confidence intervals were calculated. MAIN OUTCOME MEASURES: Birthweight, birth length, head circumference and stillbirth. Secondary outcomes included gestational age at delivery, preterm birth <37 and <34 weeks of gestation, prelabour @entity397 of membranes, Apgar score, endotracheal intubation for resuscitation, neonatal intensive care unit admission, @entity154 , @entity649 , @entity548 , neonatal @entity2348 , @entity1087 and neonatal @entity209 . RESULTS: A total of 11,852 @entity1 were included: 1202(11.1%) exposed to ETS and 10,650 (89.9%) not exposed. Exposure to ETS was an independent risk factor for lower mean birthweight (-53.7 g, 95% CI -98.4 to -8.9 g), smaller head circumference (-0.24 cm, 95% CI -0.39 to -0.08 cm), shorter birth length (-0.29 cm, 95% CI -0.51 to -0.07 cm), stillbirth (OR 3.35, 95% CI 1.16-9.72, P = 0.026), and trends towards preterm birth <34 weeks (OR 1.87, 95% CI 1.00-3.53, P = 0.05) and @entity295 (OR 2.96, 95% CI 0.99-8.86). CONCLUSIONS: Exposure of nonsmoking pregnant @entity1 to ETS is associated with a number of adverse perinatal outcomes including lower birthweight, smaller head circumference and stillbirth, as well as shorter birth length. This information is important for @entity1 , their families and healthcare providers, and reinforces the continued need for increased public policy and education on prevention of exposure to ETS.

Effects of environmental XXXX smoke on perinatal outcomes: a retrospective cohort study.

@entity1 :: ('9606', 'Species') :: ['women', 'Women'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity154 :: ('MESH:D000013', 'Disease') :: ['congenital anomalies'] @entity295 :: ('MESH:D018805', 'Disease') :: ['neonatal sepsis'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity548 :: ('MESH:D006470', 'Disease') :: ['intraventricular haemorrhage'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity649 :: ('MESH:D012128', 'Disease') :: ['respiratory distress syndrome'] @entity2348 :: ('MESH:D001424', 'Disease') :: ['bacterial sepsis'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic abnormalities']
@entity286 :: (4097,Species) :: ['tobacco']
