PURPOSE: To evaluate the vascular structure of eyes with macular @entity8721 type 2 (MacTel2) using volume-rendered optical coherence tomography angiography (OCTA). DESIGN: Retrospective cross-sectional study. @entity1 : A total of 14 consecutive @entity1 (20 eyes) with MacTel2 who had a signal strength score >= 55 and could maintain fixation during the scan process. METHODS: The eyes were scanned using optical coherence tomography with split-spectrum amplitude decorrelation techniques to derive flow information. Data were extracted and used to create volume-rendered images of the retinal vasculature that could be rotated about 3 different axes for evaluation. MAIN OUTCOME MEASURES: Descriptive appraisal of the @entity455 associated with MacTel2. RESULTS: Vessels posterior to the outer boundary of the deep retinal plexus were secondary to retinal thinning, vascular invasion, or a combination of both. These vessels had the same shape and distribution as the late staining seen during conventional @entity941 angiography. Lateral contraction in the temporal macula in 5 eyes created an appearance of vessels radiating from a central locus, which was the site of a right angle vein. Loss of macular tissue as part of the disease process led to a central amalgamation of the inner vascular plexus and the deep vascular plexus, which appeared to be in a state of decline. Subretinal neovascularization originated from the retinal circulation but involved not only the subretinal space but also could infiltrate the remaining, thinned, retina. CONCLUSIONS: Volume rendering of OCTA information preserves the 3-dimensional relationships among @entity989 and provides opportunities to visualize @entity989 in unprecedented detail. The @entity989 and invasion in MacTel2 may arise as a consequence of loss of control with depletion of M  ller cells and exposure of the remaining retinal vessels to the more @entity519 environment near the inner segments of the photoreceptors.

Volume-Rendering Optical Coherence Tomography Angiography of Macular XXXX Type 2.

@entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular abnormalities'] @entity8721 :: ('MESH:D013684', 'Disease') :: ['telangiectasia'] @entity519 :: ('MESH:D000860', 'Disease') :: ['hypoxic'] @entity941 :: ('MESH:D019793', 'Chemical') :: ['fluorescein'] @entity989 :: ('MESH:D012164', 'Disease') :: ['retinal vascular layers', 'retinal vascular abnormalities', 'retinal vascular leakage']
@entity8721 :: (MESH:D013684,Disease) :: ['Telangiectasia']
