OBJECTIVE: The purpose of this study was to evaluate the prognostic criteria of early fetal @entity14873 . DESIGN: A prospective, transvaginal ultrasound, cross-sectional study at 11-15 weeks of gestation at a tertiary referral fetal medicine unit. SUBJECTS AND METHODS: Sixteen pregnancies out of a total of 5240 were identified with early fetal @entity14873 . Fetal biometry, morphology, amniotic fluid, bladder size and volume were also evaluated. The karyotype was available in 15 cases. Vesicocentesis was performed in six fetuses and three had concomitant cystoscopies. RESULTS: In six fetuses, the @entity14873 was isolated. In the remaining ten, we detected associated @entity3609 (n = 5), nuchal translucency (n = 3), omphalocele (n = 1), mild @entity11689 (n = 1) and bilateral talipes (n = 1). In three cases the fetuses demonstrated renal hyperechogenicity with cysts, and in two cases @entity2906 was found; four cases (25%) had @entity2008 ; 47, XY + 13 (two cases), 47, XY + 18 and 47, XY + 21. Only one fetus from this study survived. In the remaining 13 cases, termination was proposed after counselling of the @entity1 on the poor prognosis. The mean gestational age at termination was 15.5 +/- 2.4 weeks (range 12-20). Three fetal transabdominal cystoscopies did not allow us to view the valves; one @entity6369 was suspected, and confirmed postnatally. CONCLUSIONS: We found a high rate of associated @entity600 , especially intestinal @entity600 . The systematic evaluation of the intestinal enzymes in the amniotic fluid and urine samples might be an important aid in the diagnosis of multiple @entity600 , such as @entity16490 .

Early fetal XXXX between 11 and 15 weeks of gestation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3609 :: ('MESH:D018191', 'Disease') :: ['hygroma'] @entity6369 :: ('MESH:D014526', 'Disease') :: ['urethral atresia'] @entity16490 :: ('MESH:D050033', 'Disease') :: ['cloacal dysgenesis'] @entity11689 :: ('MESH:D058536', 'Disease') :: ['pyelectasis'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity2906 :: ('MESH:D016104', 'Disease') :: ['oligohydramnios'] @entity14873 :: ('MESH:C536139', 'Disease') :: ['megacystis'] @entity2008 :: ('MESH:D002869', 'Disease') :: ['chromosomal abnormalities']
@entity14873 :: (MESH:C536139,Disease) :: ['megacystis']
