BACKGROUND: Diffusion tensor imaging (DTI) is based upon the phenomenon of water diffusion known as " @entity11535 ." DTI can detect changes in compressed spinal cord earlier than magnetic resonance imaging and is more sensitive to subtle pathological changes of the spinal cord. DTI observation in compressed and noncompressed spinal cord in @entity378 ( @entity378 ) spine is not described. This study presents observations in Pott's spine @entity1 with or without @entity51 . MATERIALS AND METHODS: Thirty consecutive cases of @entity378 spine with mean age of 32.1 years of either sexes with @entity75 , with/without @entity451 divided into two groups: Group A: (n = 15) without @entity451 and group B: (n = 15) with @entity451 were evaluated by DTI. The average fractional anisotropy (FA) and @entity1893 ( @entity1893 ) values were calculated at 3 different sites, above the lesion (SOL)/normal, at the lesion and below SOL for both groups and mean was compared. Visual impression of tractography was done to document changes in spinal tracts. RESULTS: The mean canal encroachment in group A was 39.60% and group B 44.4% (insignificant). Group A mean FA values above SOL, at the lesion and below SOL were 0.608    0.09, 0.554    0.14, and 0.501    0.16 respectively. For group B mean FA values above SOL, at the lesion and below SOL were 0.628    0.09, 0.614    0.12 and 0.487    0.15 respectively. There was a significant difference in mean FA above the SOL as compared to the mean FA at and below SOL. P value above versus below the SOL was statistically significant for both groups (0.04), but P value for at versus below the SOL (0.01) was statistically significant only in group B. On tractography, disruption of fiber tract at SOL was found in 14/15 (93.3%) cases of group A and 14/15 cases (93.3%) of group B (6/6 grade 4, 3/3 grade 3 and 5/6 grade 2 paraplegic cases). CONCLUSION: The FA and @entity1893 above the lesion were same as reported for healthy volunteer hence can be taken as control. FA increases, and @entity1893 decreases at SOL in severe grade of @entity451 because of epidural collection while in milder grade, both decrease. In group A (without @entity51 ), mean FA and @entity1893 in @entity1 with and without canal encroachment was similar. On tractography, both groups A and B (with or without @entity51 ) showed disruption of fiber tract at SOL and thickness of distally traced spinal cord was appreciably less than the upper cord. FA and @entity1893 could not differentiate between various grades of @entity451 . Although the number of @entity1 in each group are small.

Diffusion tensor imaging observation in Pott's spine with or without XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity75 :: ('MESH:D001927', 'Disease') :: ['paradiscal lesion'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficit', 'neural deficit'] @entity11535 :: ('MESH:D009041', 'Disease') :: ['Brownian motion'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['MD', 'mean diffusivity'] @entity451 :: ('MESH:C536857', 'Disease') :: ['paraplegia'] @entity378 :: ('MESH:D014376', 'Disease') :: ['TB', 'tuberculosis']
@entity51 :: (MESH:D009461,Disease) :: ['neurological deficit']
