Occult @entity0 presenting with axillary lymph node @entity3 is uncommon, and @entity0 ( @entity0 ), as a subtype, is quite rare. Here we describe a case of @entity0 , which arose as an unknown primary @entity189 ; the @entity1 presented with axillary lymph node @entity3 , and was successfully treated with trastuzumab and @entity1206 . Specifically, a 55-year-old @entity1 presented with right @entity3329 . Although she underwent various examinations, the primary site of the disease was not revealed. Axillary lymph node dissection was performed, and the lesion was diagnosed as a poorly differentiated @entity420 . The @entity1 chose to be treated by alternative medicine. About 6 months later, she was referred to our hospital, due to marked bilateral neck and axillary lymph node swelling. She presented with diffuse right breast enlargement, redness, and peau d'orange. Computed tomography (CT) of the breast showed skin thickening and swelling of the right breast.F-18 Fluorodeoxyglucose positron emission tomography (FDG-PET) showed FDG uptake in the right breast. The @entity1 was clinically diagnosed with @entity0 . Because overexpression of the @entity1 @entity1722 ( @entity1722 ) was found in the specimen from her right axillary lymph node, she was treated with trastuzumab and @entity1206 . Two months after the start of chemotherapy, CT revealed a complete response in the lymph nodes, and the skin thickening and parenchymal @entity4 of the right breast had improved. FDG-PET was also performed at this time, and revealed no FDG uptake in either the right breast or the lymph nodes.

Unknown primary @entity189 , diagnosed as XXXX ,and successfully treated with trastuzumab and @entity1206 .

@entity1 :: ('9606', 'Species') :: ['woman', 'human', 'patient'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['axillary lymphadenopathy'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer', 'IBC', 'inflammatory breast cancer'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity1206 :: ('MESH:C030852', 'Chemical') :: ['vinorelbine'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity1722 :: ('2064', 'Gene') :: ['epidermal growth factor receptor 2', 'HER2']
@entity0 :: (MESH:D001943,Disease) :: ['inflammatory breast cancer']
