BACKGROUND: @entity31 ( @entity31 ) is typically a continuous and diffuse @entity32 extending proximally from the rectum. However, @entity75 in the appendiceal region has been reported recently. Although appendectomy has been shown to reduce the risk of @entity31 , the clinical significance of @entity75 remains unclear. The present study examined the relationship between the continuous distal lesion of @entity31 and the @entity75 by observing colonoscopic changes in both lesions. METHODS: Among 279 @entity1 with @entity31 who underwent total colonoscopy from January 1994 to December 2000, 54 @entity1 (19.4%) had @entity75 . Serial colonoscopic examinations were performed in 35 of the 54 @entity1 to determine the activities in the @entity31 and @entity75 during the course of disease. RESULTS: @entity1 with @entity75 were younger and had a longer history of @entity31 than those without them, but no differences in sex ratio and treatment modality were observed between the two groups. In 28 of 35 @entity1 (80%), the activity in the distal lesion correlated well with that in the @entity75 . Both lesions were improved in 17 @entity1 , unchanged in 5 @entity1 and worsened in 6 @entity1 . Linear regression analysis showed a significant correlation between the changes in colonoscopic activity index in the two lesions. CONCLUSION: A close association is found between disease activity in the @entity75 and that in the distal lesion of @entity31 .

Clinical and colonoscopic investigation of XXXX in @entity31 .

@entity75 :: ('MESH:D001927', 'Disease') :: ['skipped periappendiceal lesion', 'skipped lesion', 'skipped periappendiceal lesions'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity31 :: ('MESH:D003093', 'Disease') :: ['UC', 'Ulcerative colitis', 'distal UC lesion']
@entity75 :: (MESH:D001927,Disease) :: ['skipped periappendiceal lesions']
