BACKGROUND: To clarify the implications and limitations of external beam radiation monotherapy for localized @entity263 , the long-term outcomes and prognostic factors were investigated. METHODS: Between 1976 and 1994, 91 @entity1 with @entity263 were treated with external beam radiation therapy alone. Thirty-two were classified as T1b, eight were T2a, four were T2b and 47 were T3. Pelvic lymphadenectomy was carried out in 69 cases; 57 were staged as pN0, eight were @entity3121 , four were @entity477 and 22 were pNX. Linac X-rays were used in 55 cases, fast neutron in 15 and a combination of the two in 21. No other therapy was given until relapse and when relapse was evident endocrine therapy was started. RESULTS: The observation period ranged from 3 to 206 months with a median of 78 months. Local control rate and disease-free, cause-specific and overall survivals at 10 years were 74.0, 49.6, 74.2 and 39.2%, respectively. By univariate analysis, T category, pN category and histologic grade were significant prognostic indicators for disease-free survival. Multivariate analysis revealed that T category was an independent prognostic factor. In T2b and T3 diseases, pN0/1 @entity1 demonstrated significantly better disease-free survival than pNX. CONCLUSIONS: A favorable long-term outcome was achieved by external beam radiation monotherapy in @entity1 with minimally extended @entity263 (T1b and T2a). For locally advanced disease (T2b and T3), staging pelvic lymphadenectomy would be useful for the selection of @entity1 .

External beam radiation monotherapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3121 :: ('5270', 'Gene') :: ['pN1'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer', 'untreated prostate cancer'] @entity477 :: ('351', 'Gene') :: ['pN2']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
