PURPOSE: To compare the intraocular pressure-lowering effect and safety of viscocanalostomy and trabeculectomy with @entity1138 . METHODS: Twenty-five @entity1 with bilateral primary @entity1538 were enrolled in a prospective clinical study. The eyes of each @entity1 were randomly assigned to receive viscocanalostomy in one eye and trabeculectomy with @entity1138 in the other eye. The @entity1 were followed up for 12 months. At each visit, best-corrected visual acuity, intraocular pressure, and the appearance of the surgical wound, anterior chamber, and indirect ophthalmoscopy were recorded. RESULTS: The mean baseline intraocular pressure was 25.0+/-2.2 mmHg in @entity735 and 24.8+/-2.6 mmHg in trabeculectomy-treated eyes. The mean postoperative intraocular pressure was 15.3+/-1.7 mmHg, 17.1+/-1.5 mmHg, and 17.1+/-1.5 mmHg in @entity735 and 11.7+/-4.4 mmHg, 11.8+/-4.6 mmHg, and 12.6+/-4.3 mmHg in trabeculectomy-treated eyes at 3-, 6- and 12-month intervals, respectively. The mean intraocular pressure in @entity735 was significantly higher than that in trabeculectomy-treated eyes at every visit (P<0.0001). At 12 months, 16 @entity735 (64%) and 22 trabeculectomy-treated eyes (88%) achieved an intraocular pressure of less than or equal to 20 mmHg without medication; there was a significant difference between the two groups (P=0.0240). There were fewer complications in @entity735 . Complications included four cases of @entity8707 (16%) and five of @entity8814 (20%) in trabeculectomy-treated eyes, against intraoperative microperforation of Descemet's membrane in one of @entity735 (4%). CONCLUSION: Trabeculectomy with @entity1138 may be more effective than viscocanalostomy in lowering intraocular pressure in @entity1 with primary @entity1538 , while eyes undergoing viscocanalostomy experience a lower incidence of complications. Further investigation of more cases is needed.

A comparison of the intraocular pressure-lowering effect and safety of viscocanalostomy and trabeculectomy with @entity1138 in bilateral XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open-angle glaucoma'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin C'] @entity8707 :: ('MESH:C535679', 'Disease') :: ['shallow anterior chamber'] @entity8814 :: ('MESH:D015814', 'Disease') :: ['hypotony'] @entity735 :: ('MESH:D005124', 'Disease') :: ['viscocanalostomy-treated eye', 'viscocanalostomy-treated eyes']
@entity1538 :: (MESH:D005902,Disease) :: ['open-angle glaucoma']
