BACKGROUND: Obesity is prevalent in @entity1 with @entity73 , but the risks and benefits in this complex group are unknown. OBJECTIVES: The aim of this study was to assess outcomes in a small cohort of @entity1 with lifelong @entity73 who underwent bariatric surgery and to introduce important concepts when considering surgery in this complex group. SETTING: Academic institution, United States. METHODS: We retrospectively analyzed all @entity1 with an objective psychological and/or neuropsychological diagnosis of lifelong, nonacquired @entity73 who had bariatric surgery at our center. RESULTS: We identified 6 @entity1 with a diagnosis of nonacquired @entity73 who underwent a bariatric procedure. The cohort (3 male, 3 female) had a mean age of 33.3 years and a mean body mass index (BMI) of 49.4 kg/m(2). Two of the @entity1 had a diagnosis of trisomy 21, and the other 4 @entity1 had lifelong @entity73 from unknown causes. The distribution of surgical approaches was 2 laparoscopic Roux-en-Y gastric bypasses (LRYGBs), 3 laparoscopic sleeve gastrectomies (SGs), and 1 laparoscopic adjustable gastric band (LAGB). There were no complications and no mortality. At a mean follow-up of 33.7 months, the cohort had a mean percent excess @entity353 (%EWL) of 31.1% (range -1.8%-72.2%). Two @entity1 achieved a %EWL>50%. CONCLUSIONS: This case series suggests that bariatric surgery can be performed with minimal morbidity in @entity1 with nonacquired @entity73 after intensive multidisciplinary management. However, it appears this population may lose less weight than what is reported for @entity1 without cognitive delay.

Bariatric surgery in the XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss']
@entity73 :: (MESH:D003072,Disease) :: ['cognitively impaired']
