Thirty-eight cases clinically diagnosed as @entity1442 were subject to splenectomy in Dongzhi County Special Hospital for Schistosomiasis because of portal @entity101 , @entity381 and/or @entity6118 . Liver biopsy was undertaken in all cases during surgical intervention. Before operation, ultrasonography on the liver and spleen was carried out. Also done was biochemical assay on several indices related to @entity409 and @entity82 . Among the 38 cases, 24 were diagnosed as @entity2040 by the finding of eggs in feces, 13 were diagnosed by positive serological test with IHA or COPT, and only in one case, the diagnosis of @entity2040 was doubtful before operation. However, the eggs were found in the liver section upon histological examination. All the 38 cases had symptoms and signs of portal @entity101 and most of them had general symptoms. Histories of hematemesis and melena were recorded in three cases. The causes of hospitalization were mainly @entity381 and @entity1661 , and two were suffering from @entity360 . Upon histopathological examination, schistosome eggs were found in 33 out of 38 cases. Advanced schistosomaiasis was shown in 18 cases and @entity2040 associated with @entity99 or @entity82 was seen in other 20 @entity1 . The main pathological changes were egg @entity738 with different degrees of @entity82 and some differences in the pathological changes between @entity1575 ( @entity1575 ) and mixed @entity1575 (both schistosome and @entity99 in origin) were seen. Compared with normal ultrasonography, in all the 38 cases, the length of the left and right liver, and the spleen, and the thickness of the left liver, the width of portal trunk, were all out of normal ranges. The differences between the @entity1 and normal records were significant. However, there were no statistically significant differences in terms of above-mentioned indices as well as liver parenchyma changes on ultrasound between advanced schistosomaiasis and @entity2040 complicated with @entity99 or @entity82 (all P>0.5). According to WHO classification criteria on ultrasonography for @entity2040 , among 20 cases combined with @entity99 or @entity82 , 11 cases fell in Grade II, and nine cases in @entity1575 , whereas among 18 cases with @entity2040 @entity82 , 12 and six were in Grade II and III, respectively. The mean value of serum MAO, PIIIP, IVC and HA in the 38 cases were all significantly higher than normal range. However, no significant differences (all P>0.1) were seen between advanced @entity2040 and those complicated with @entity99 or @entity82 in terms of the levels of the four indices. The results showed that ultrasonography has its importance in the diagnosis and evaluation of liver @entity82 . However, in differentiation of the two types of @entity409 , ultrasound does not provide important information. Histopathological examination, on the other hand, can provide useful information to identify the @entity99 .

Study on histopathology, ultrasonography and some special serum enzymes and collagens for 38 advanced XXXX of @entity2040 japonica.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis', 'cirrhosis'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity738 :: ('MESH:D006099', 'Disease') :: ['granulomas'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver damage'] @entity1661 :: ('MESH:D000008', 'Disease') :: ['abdominal distension'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['advanced schistosomiaisis'] @entity381 :: ('MESH:D013163', 'Disease') :: ['splenomegaly'] @entity2040 :: ('MESH:D012552', 'Disease') :: ['schistosomiasis'] @entity6118 :: ('MESH:D006971', 'Disease') :: ['hypersplenism'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['SLF', 'Grade III hepatic fibrosis', 'schistosomal liver fibrosis', 'liver cirrhosis'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic diseases', 'hepatitis'] @entity360 :: ('MESH:D006471', 'Disease') :: ['upper gastrointestinal bleeding']
@entity1 :: (9606,Species) :: ['patients']
