UNASSIGNED: @entity4876 modulates intestinal epithelial cell structure and function. Three hundred and sixty Lohmann LSL-Classic layer cockerels were used to investigate the effect of @entity4876 on @entity8291 -induced @entity1944 and intestinal integrity. The experiment was conducted from day 85 to 105 of age. The birds were divided randomly into three treatments: control, @entity8291 ( @entity8291 ), and @entity8291 provided with @entity4876 (HSB) at a level of 0.35  g/kg of diet. The control was reared at 21      1    C throughout the experiment. The @entity8291 and HSB treatments were exposed to a cyclic @entity8291 (35      1    C from 09:00 to 13:00 and 21      1    C from 13:00 to 09:00). Intestinal and mucosal weights, villus height, villus surface area (VSA), absorptive epithelial cell area and intestinal beneficial bacteria were lower in the @entity8291 treatment than in the other two treatments (p  <  0.05). Heat-stressed cockerels exhibited the highest (p  <  0.05) villi injury scores and serum endotoxin levels compared with the other treatments. Dietary inclusion of @entity4876 increased (p  <  0.05) intestinal and mucosal weights, villus height, VSA, absorptive epithelial cell area and intestinal beneficial bacteria counts and reduced (p  <  0.05) @entity8291 -induced @entity1944 as well as intestinal permeability to endotoxin. In conclusion, dietary @entity4876 exerted protective effects against @entity16 induced by @entity8291 and improved intestinal health and integrity.

Effects of dietary XXXX supplementation on intestinal integrity of heat-stressed cockerels.

@entity1944 :: ('MESH:D007410', 'Disease') :: ['injury in intestinal epithelia', 'intestinal injury'] @entity4876 :: ('MESH:D002087', 'Chemical') :: ['Butyrate', 'butyrate'] @entity8291 :: ('MESH:D018882', 'Disease') :: ['heat stress', 'HS'] @entity16 :: ('MESH:D009422', 'Disease') :: ['intestinal damage']
@entity4876 :: (MESH:D002087,Chemical) :: ['butyrate']
