There are many studies supporting the family history in @entity2 . The study included 213 subjects with new and former diagnoses of @entity2 . @entity1 were enrolled from the Department of @entity764 Ankara University Faculty of Medicine and Atat  rk @entity764 and Chest Surgery Training and Research Hospital between January-June 2005. For the control group, 200 healthy subjects were gathered. We aimed to investigate the family predisposition for lung and other @entity5 , additionally the relationship of this predisposition to age, gender, smoking habits and cell types. The number of first degree relatives of @entity1 and control group were 2058 and 2045, respectively. In conclusion, positive family history for @entity5 estimated in 38% of 213 individuals with @entity2 . In these individuals, 41.9% had @entity2 , 19% had @entity1820 , 7.6% had @entity0 , 5.7% had @entity263 , 25.7% had other @entity5 (larinx, skin, bone, hematologic system, central nervous system). Besides, 4.6% of 213 @entity1 had accompanying other @entity5 (urinary bladder, kidney, lung, head-neck). In control group, positive family history for the @entity5 was 21.5% and this was statistically significant (p< 0.001). In the family members of @entity1 with @entity2 , the risks of lung, gastrointestinal system and @entity0 development were increased. Besides, the @entity2 (except prostate and @entity1820 ) were significantly increased at the brothers of @entity1 with @entity2 , supporting the genetical transition hypothesis. The presence of head-neck, @entity263 in the history of the @entity1 increase the risk of @entity2 , supporting the genetic transition.

[Lung XXXX and family history of @entity5 ].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['bladder, prostate, lung and kidney cancers', 'prostate cancer'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'cancer', 'system cancers'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer', 'lung and other system cancers'] @entity764 :: ('MESH:D013898', 'Disease') :: ['Chest Diseases'] @entity1820 :: ('MESH:D005770', 'Disease') :: ['gastrointestinal system cancers', 'gastrointestinal system cancer']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
