UNASSIGNED: The depletion of three banned @entity9110 drugs - @entity5801 (DMZ), @entity868 (MNZ) and @entity5802 (RNZ) - was investigated in @entity12429 ( @entity12429 ) following in-water medication. The highest concentrations of residues were measured immediately after the 24-h immersion (d0). At this time, MNZ and MNZ- @entity2145 residues were measured in shrimp tissue samples at concentrations ranging from 361 to 4189 and from 0.28 to 6.6   g  kg(-1), respectively. DMZ and its metabolites HMMNI ranged in concentration between 31  509 and 37  780 and between 15.0 and 31.9   g  kg(-1), respectively. RNZ and HMMNI concentrations ranged from 14  530 to 24  206 and from 25.0 to 55   g  kg(-1), respectively. MNZ, DMZ and RNZ were the more persistent marker residues and can be detected for at least 8 days post-treatment. MNZ-OH was only detectable on d0 following treatment with MNZ. HMMNI residues were only detectable up to d1 (0.97-3.2   g  kg(-1)) or d2 (1.2-4.5   g  kg(-1)) following DMZ and RNZ treatment, respectively. The parent drugs MNZ, DMZ and RNZ were still measureable on d8 at 0.12-1.0, 40.5-55 and 8.8-18.7   g  kg(-1), respectively. The study also investigated the stability of @entity9110 residues under various cooking procedures (frying, grilling, boiling, and boiling followed by microwaving). The experiments were carried out in shrimp muscle tissue containing both high and low concentrations of these residues. Different cooking procedures showed the impact on @entity9110 residue concentration in shrimp tissue. Residue concentration depleted significantly, but partially, by boiling and/or microwaving, but the compounds were largely resistant to conventional grilling or frying. Cooking cannot therefore be considered as a safeguard against harmful @entity9110 residues in shrimp.

Determination of the persistence of XXXX , @entity868 and @entity5802 residues in @entity12429 ( @entity12429 ) tissue and their stability during cooking.

@entity12429 :: ('6687', 'Species') :: ['black tiger shrimp', 'Penaeus monodon'] @entity868 :: ('MESH:D008795', 'Chemical') :: ['metronidazole'] @entity9110 :: ('CHEBI:67135', 'Chemical') :: ['nitroimidazole'] @entity5801 :: ('MESH:D004131', 'Chemical') :: ['dimetridazole'] @entity5802 :: ('MESH:D012385', 'Chemical') :: ['ronidazole'] @entity2145 :: ('MESH:C031356', 'Chemical') :: ['OH']
@entity5801 :: (MESH:D004131,Chemical) :: ['dimetridazole']
