BACKGROUND: To investigate the impact of prolonged length of stay (LoS) on long-term mortality in @entity1 who have undergone curative resection for @entity418 ( @entity418 ). METHODS: Between January 2001 and December 2009, @entity1 who underwent an esophagectomy for @entity418 at Fudan University Shanghai Cancer Center were enrolled in this study. We retrospectively analyzed the medical charts of all of the enrolled @entity1 . To determine the effect of postoperative LoS on long-term survival, we separated the @entity1 into three groups based on the lengths of their postoperative LoS, including an LoS of less than 2 weeks (Group 1,  <=2 W), an LoS between 2 and 3 weeks (Group 2,  <=3 W) and an LoS of more than 3 weeks (Group 3, >3 W). Perioperative and long-term outcomes were compared between the groups. RESULTS: In total, 348 @entity1 were included in this study. All of the @entity1 underwent an esophagectomy with 3-field lymph node dissection (3FLND). The median postoperative hospital stay was 14 days (range: 8-153 days). Complications were observed in 123 @entity1 (15.9% in Group 1 vs. 73.2% in Group 2 vs. 96.6% in Group 3, P<0.001). The median duration of follow-up was 39 months (range: 3-120 months). There were significant reductions in preventive adjuvant therapy (P=0.003) and postoperative salvage therapy (P<0.001) among the three groups. The 5-year survival rate was significantly different among the groups (43% vs. 36% vs. 29%, respectively, P=0.006). There was no difference in the 5-year disease-free survival rate among the three groups (23% vs. 21% vs. 19%, P=0.238). CONCLUSIONS: Prolonged LoS was significantly associated with reduced rates of overall survival (OS). The insufficient administration of adjuvant therapy may partly account for these findings.

Prolonged postoperative length of stay is associated with poor overall survival after an esophagectomy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal cancer', 'EC']
@entity418 :: (MESH:D004938,Disease) :: ['esophageal cancer']
