BACKGROUND AND OBJECTIVES: Over the last two decades, both the incidence of @entity580 and the proportion of blood stream infection due to Candida spp. other than @entity5132 have increased. The aims of this study was to identify different species of Candida and risk factors associated with @entity281 and detection of biofilm production. MATERIALS AND METHODS: This study was conducted in an 840 bedded tertiary care hospital, over a period of one year. All blood isolates received from @entity1 during this period were screened for @entity4963 prospectively. Speciation was carried out by standard microbiological method. Biofilm production detection was done by Brachini et al method. RESULT: A total of 80 cases of @entity4963 were identified. Most important risk factor was placement of vascular access devices in all the age groups. @entity5132 accounted for 22 isolates (27.5%) whereas non-albicans Candida spp. accounted for 58 isolates (72.5%). Biofilm production was found in 31 strains (38.75%). Biofilm production was seen more in non-albicans Candidaspp. (83.87%) especially in @entity9841 (66.67%, 8 of 12). CONCLUSIONS: Non-albicansspecies of Candida were most frequently recovered in our study. So, the epidemiology of @entity6923 is changing. Non-albicans Candida spp have the capacity to produce significant amount of biofilm which may be the cause of their reduced susceptibility to antifungal agents.

Clinico-microbiological study of XXXX in a tertiary care hospital of southern part of India.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity9841 :: ('5482', 'Species') :: ['C. tropicalis'] @entity6923 :: ('MESH:C536777', 'Disease') :: ['Candida infection'] @entity4963 :: ('MESH:D058387', 'Disease') :: ['candidemia'] @entity5132 :: ('5476', 'Species') :: ['Candida albicans'] @entity281 :: ('MESH:D007239', 'Disease') :: ['bloodstream infection'] @entity580 :: ('MESH:D003428', 'Disease') :: ['nosocomial candidaemia']
@entity4963 :: (MESH:D058387,Disease) :: ['candidemia']
