BACKGROUND: There is extensive and consistent evidence that high fruit and vegetable intakes are associated with decreased risks of many @entity5 , but results for @entity263 risk have been inconsistent. We studied the associations of fruit and vegetable intakes with @entity263 risk in a population-based, case-control study of @entity1 under 65 years of age. METHODS: Case @entity1 were 628 @entity1 from King County (Seattle area), WA, who were newly diagnosed with @entity263 . Control @entity1 were 602 @entity1 recruited from the same underlying population and frequency matched to case @entity1 by age. Self-administered food-frequency questionnaires were used to assess diet over the 3- to 5-year period before diagnosis or recruitment. Daily nutrient intakes were calculated by use of a nutrient database with recently updated analytic values for carotenoids. Odds ratios for @entity263 risk associated with foods and nutrients were calculated by use of unconditional logistic regression. RESULTS: No associations were found between fruit intake and @entity263 risk. The adjusted odds ratio (ORs) for the comparison of 28 or more servings of vegetables per week with fewer than 14 servings per week was 0.65 (95% confidence interval [CI] = 0.45-0.94), with a two-sided P for trend =.01. For cruciferous vegetable consumption, adjusted for covariates and total vegetable intake, the OR for comparison of three or more servings per week with less than one serving per week was 0.59 (95% CI = 0.39-0.90), with a two-sided P for trend =.02. The OR for daily intake of 2000 microg or more @entity8665 plus @entity7695 compared with an intake of less than 800 microg was 0.68 (95% CI = 0.45-1.00). CONCLUSION: These results suggest that high consumption of vegetables, particularly cruciferous vegetables, is associated with a reduced risk of @entity263 .

Fruit and vegetable intakes and XXXX risk.

@entity1 :: ('9606', 'Species') :: ['participants', 'men'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers'] @entity7695 :: ('MESH:C005881', 'Chemical') :: ['zeaxanthin'] @entity8665 :: ('MESH:D014975', 'Chemical') :: ['lutein']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
