OBJECTIVE To evaluate how age affects functional outcome and quality of life after ileal pouch anal @entity254 (IPAA). SUMMARY BACKGROUND DATA Because of the limited number of older @entity1 undergoing IPAA, it has been difficult to assess functional outcome and quality of life stratified by age. METHODS IPAA was performed in 1895 @entity1 . @entity1 were stratified by age into <45 (n = 1410), 46-55 (n = 289), 56-65 (n = 154), and more than 65 years (n = 42). Outcome was assessed prospectively. Results are presented at 1, 3, 5, and 10 years after surgery.RESULTS @entity1 were followed for 4.6 +/- 3.7 years (maximum, 17 years). Pouch failure occurred in 4.1% (pouch excision or permanent diversion). @entity322 and night time seepage were more common in older @entity1 . There were minor differences in the quality of life, health, energy and happiness between age groups, with a slight benefit for those under 45 years. Fourteen percent or fewer @entity1 experienced social, @entity458 . Overall, 96% of @entity1 were happy to have undergone their surgery, and 98% recommended it to others. Although the respective figures were 89% and 96% in the over-65 age group, the difference was not significant. CONCLUSIONS These data provide a unique assessment of outcome after IPAA at multiple time points. Although functional outcome after IPAA is not as good in older @entity1 , appropriate case selection confers acceptable function and quality of life to @entity1 of all ages.

Prospective, age-related analysis of surgical results, functional outcome, and quality of life after ileal pouch-anal XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity322 :: ('MESH:D014549', 'Disease') :: ['Incontinence'] @entity458 :: ('MESH:D020018', 'Disease') :: ['sexual or work restrictions']
@entity254 :: (MESH:C563598,Disease) :: ['anastomosis']
