BACKGROUND: Acute @entity1778 and bone marrow transplantation (BMT) as a method of its treatment are great psychological stressors, which are responsible for @entity148 and @entity308 in the group of @entity1 . The aim of the study was to assess the @entity1 ' mental state and its psychophysical predictors before and after BMT. SUBJECT AND METHOD: The study was of a longitudinal and self-descriptive character. The questionnaires: LOT-R, AIS, Mini-Mac, CECS, RSCL and HADS were filled by 60 @entity1 with @entity1778 before and after BMT. RESULTS: There were no essential statistical differences between the severity of @entity148 and @entity308 before and after BMT but the pattern and the power of various mental state predictors changed in the course of the hospitalization. @entity148 before transplantation was greater when the psychological stress and the strategy of "anxious preoccupation" were stronger and the strategy of "fighting spirit" and the level of generalized optimism were weaker. The factors explained 51% variations of @entity148 before transplantation. After BMT 77% variations of @entity148 were explained, which were associated with a high level of distress at the end of the hospitalization, higher level of @entity148 before transplantation, weaker strategy of "fighting spirit" before transplantation and stronger strategy of "anxious preoccupation" after BMT. Before transplantation 36% variations of @entity308 were explained and estimated as weaker "fighting @entity2026 ". The essential predictors of @entity308 after transplantation, explained by 81% variations of @entity308 , were weaker "fighting spirit" before transplantation, stronger "anxious preoccupation" after transplantation, worse "global life quality" after transplantation and higher level of anxious and @entity308 on admission to hospital. CONCLUSION: The psychological and pharmacological interventions, which reduce @entity148 , @entity308 and "anxious preoccupation" as well as enhance "fighting spirit", should be introduced before BMT to improve the @entity1 ' mental state.

Mental state and its psychophysical conditions in @entity1 with XXXX treated with bone marrow transplantation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive symptoms', 'depression'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['leukaemia', 'acute leukaemia'] @entity148 :: ('MESH:D001008', 'Disease') :: ['Anxiety', 'anxiety'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['spirit" and worse "global life quality']
@entity1778 :: (MESH:D007938,Disease) :: ['acute leukaemia']
