BACKGROUND: Epidemiological surveillance in Uganda has consistently shown declining @entity645 prevalence particularly among young antenatal @entity1 since the early 1990s, correlated with increased uptake of protective @entity458 . OBJECTIVE: To describe trends in @entity458 nationwide and antenatal @entity645 prevalence from urban sentinel sites in Uganda (1989-2002). METHODS: Review of antenatal @entity645 seroprevalence data from the sentinel surveillance system (1989-2002) and data on sexual behavioural indicators from the AIDS module of the National Demographic and Health Surveys (1989, 1995 and 2000/01). Trends in biological and behavioural indicators assessed. RESULTS: Antenatal @entity645 seroprevalence in seven urban clinics peaked around 1992 (15-30%) followed by a steady decline by 2002 (5-12%), most markedly among @entity1 aged 15-19 and 20-24 years. This coincided with increased primary and secondary abstinence among young @entity1 nationwide. Median age at sexual debut increased from 16.5 in 1989 to 17.3 in 2000 for @entity1 and from 17.6 in 1995 to 18.3 in 2000 for @entity1 . Premarital sex among @entity1 and multiple partnerships decreased between 1995 and 2000. There were no significant changes in reporting of extramarital sex among @entity1 . Ever use of condoms increased from 1% among @entity1 in 1989 and 16% among @entity1 in 1995 to 16% and 40% in 2000, respectively. Between 1995 and 2000, condom use at last sex with a non-regular partner increased from 35% to 59% and 20% to 39% among @entity1 and @entity1 , respectively. CONCLUSION: The ecological correlation between the trends in @entity645 prevalence and incidence and the increase in protective @entity458 during the 1990s makes a compelling case for continuing prevention efforts in Uganda.

Trends in antenatal @entity645 prevalence in urban Uganda associated with uptake of preventive XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'people', 'men'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity458 :: ('MESH:D020018', 'Disease') :: ['sexual behaviour']
@entity458 :: (MESH:D020018,Disease) :: ['sexual behaviour']
