This study was designed to analyze the flow and distribution of @entity4625 ( @entity4625 ) in vertebral body through computer simulation. Cadaveric lumbar vertebrae were scanned through electron beam tomography (EBT). The data was imported into Mimics software to build computational model. Vertebral body center and junction of pedicle and vertebral body were chosen as injection points. @entity1346 oil with viscosity of 100,000   cSt matching with @entity4625 bone cement was chosen for injection. The flow and distribution of @entity1346 oil were analyzed using Fluent software. In vertebral body, @entity1346 oil formed a circle-like shape centered by injection point on transverse and longitudinal sections, finally forming a sphere-like shape as a whole. @entity1346 oil diffused along lateral and posterior walls forming a circle-like shape on transverse section centered by injection point in pedicle, eventually forming a sphere-like shape as a whole. This study demonstrated that @entity1346 oil flowed and diffused into a circle-like shape centered by injection point and finally formed a sphere-like shape as a whole in both vertebral body and pedicle. The flow and distribution of @entity6619 oil in computational model could simulate @entity4625 distribution in vertebral body. It may provide theoretical evidence to reduce @entity4625 leakage risk during percutaneous vertebroplasty.

Computer Simulation and Analysis on Flow Characteristics and Distribution Patterns of XXXX in Lumbar Vertebral Body and Vertebral Pedicle.

@entity4625 :: ('MESH:D019904', 'Chemical') :: ['polymethylmethacrylate', 'PMMA'] @entity1346 :: ('MESH:D012828', 'Chemical') :: ['Silicone', 'silicone'] @entity6619 :: ('MESH:D012825', 'Chemical') :: ['silicon']
@entity4625 :: (MESH:D019904,Chemical) :: ['Polymethylmethacrylate']
