UNASSIGNED: In @entity1 , invalid visual targets that mismatch spatial expectations induced by attentional cues are considered to selectively engage a right hemispheric "reorienting" network that includes the temporal parietal junction (TPJ), the inferior frontal gyrus (IFG), and the medial frontal gyrus (MFG). However, recent findings suggest that this hemispheric dominance is not absolute and that it is rather observed because the TPJ and IFG areas in the left hemisphere are engaged both by invalid and valid cued targets. Because of this, the BOLD response of the left hemisphere to invalid targets is usually cancelled out by the standard "invalid versus valid" contrast used in functional magnetic resonance imaging investigations of spatial attention. Here, we used multivariate pattern recognition analysis (MVPA) to gain finer insight into the role played by the left TPJ and IFG in reorienting to invalid targets. We found that in left TPJ and IFG blood @entity26 level-dependent (BOLD) responses to invalid and valid targets were associated to different patterns of neural activity, possibly reflecting the presence of functionally distinct neuronal populations. Pattern segregation was significant at group level, it was present in almost all of the @entity1 to the study and was observed both for targets in the left and right side of space. A control whole-brain MVPA ("Searchlight" analysis) confirmed the results obtained in predefined regions of interest and highlighted that also other areas, that is, superior @entity550 , show different patterns of BOLD response to valid and invalid targets. These results confirm and expand previous evidence highlighting the involvement of the left hemisphere in reorienting of visual attention (Doricchi et al. 2010; Dragone et al. 2015). These findings suggest that asymmetrical reorienting deficits suffered by right brain damaged @entity1 with left @entity1057 , who have @entity73 in contralesional reorienting and less @entity73 in ipsilesional reorienting, are due to preserved reorienting abilities in the intact left hemisphere.

The Response of the Left Ventral Attentional System to Invalid Targets and its Implication for the XXXX : a Multivariate fMRI Investigation.

@entity1 :: ('9606', 'Species') :: ['participants', 'humans', 'patients'] @entity550 :: ('MESH:D000303', 'Disease') :: ['parietal and frontal-polar cortex'] @entity73 :: ('MESH:D003072', 'Disease') :: ['severe impairments'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1057 :: ('MESH:D058069', 'Disease') :: ['spatial neglect']
@entity1057 :: (MESH:D058069,Disease) :: ['Spatial Neglect Syndrome']
