UNASSIGNED: Abnormalities in total @entity4612 (tMg) concentration in plasma and/or serum are common in @entity3124 @entity1 , and the association with increased mortality has been documented in several clinical studies in adults and newborns with @entity2806 . Abnormalities in tMg were studied in hospitalized @entity235 , @entity468 , and adult @entity1641 . Newborn foals were scarcely studied with regard to @entity4612 concentration. The aims of the present study were: (1) to compare two analytical methods for the determination of tMg in plasma: the automated colorimetric method and the atomic absorption spectrometry; (2) to measure plasma tMg in healthy foals during the first 72  hours after birth and in sick foals during the first 72  hours of hospitalization; (3) to compare total plasma @entity4612 concentration among healthy foals, foals affected by @entity1763 ( @entity1763 ), prematurity and/or dismaturity, and @entity295 ; (4) to evaluate tMg plasma concentration in surviving and non-surviving foals. One hundred seventeen foals were included in the study: 20 healthy and 97 sick foals. The automated method used in clinical practice probably overestimates plasma tMg. Due to its higher sensitivity and specificity, the atomic absorption spectrometry should be considered the method of choice from an analytical point of view, but requires an instrumentation not easily available in any laboratory and specific technical skills and competencies. Plasma tMg in healthy foals were included in the range 0.52 to 1.01  mmol/L and did not show any time-dependent change during the first 72  hours of life. In sick foals, tMg evaluated at T0 was statistically higher than tMg measured at subsequent times. Foals affected by @entity1763 had a tMg at T0 significantly higher (P  <  0.01) than healthy, septic, and premature and/or dysmature foals. The t test found significantly higher (P  <  0.01) plasma tMg measured at T0 in non-surviving than in surviving foals. Plasma tMg could be a useful parameter for the diagnosis of @entity1763 and the formulation of the prognosis in @entity3124 foals.

Total plasma magnesium in healthy and XXXX foals.

@entity1 :: ('9606', 'Species') :: ['humans'] @entity4612 :: ('D008274', 'Chemical') :: ['Mg'] @entity1641 :: ('9796', 'Species') :: ['horses'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['hypoxic-ischemic encephalopathy'] @entity235 :: ('9615', 'Species') :: ['dogs'] @entity3124 :: ('MESH:D016638', 'Disease') :: ['critically ill'] @entity1763 :: ('MESH:D001237', 'Disease') :: ['perinatal asphyxia syndrome', 'PAS'] @entity468 :: ('9685', 'Species') :: ['cats']
@entity3124 :: (MESH:D016638,Disease) :: ['critically ill']
