UNASSIGNED: Recently, a new glomerular filtration rate (GFR) equation for the Japanese population was proposed using measured inulin clearance. To expand its applicability to other Asian populations, we performed a comparative study in the Korean population. Inulin clearance was measured in 166 @entity1 from seven participating medical centers in Korea. @entity1 's sera and urine were collected, and baseline clinical characteristics were measured to provide an estimated GFR (eGFR) by the Japanese GFR equation using inulin clearance (Japanese-GFR equation), the @entity8 ( @entity8 ) study equation, and the @entity740 - Epidemiology Collaboration (CKD-EPI) equation. We compared the results to determine which equation best estimated the measured GFR (mGFR). Accuracy (95% CI) within 30% of mGFR by the Japanese-GFR equation, the CKD-EPI equation and the @entity8 study equation were 66 (58 - 72), 51 (43 - 58), and 55 (47 - 62)%, respectively. Bias (mGFR minus eGFR) were 3.4    22.4, -12.0    22.1, and -9.7    23.8 mL/min/1.73 m2, respectively. The accuracy of the Japanese-GFR equation was significantly better than @entity8 study equation in subjects with mGFR < 60 mL/min/1.73 m2 and in total subjects. The bias of the Japanese-GFR equation was significantly smaller compared with other two equations in total subjects. The Japanese-GFR equation has a higher accuracy with less bias than the other equations in estimating GFR in Korean populations. Further studies are required to determine if the current Japanese-GFR equation could represent the standard eGFR for other Asian populations.

Is the new GFR equation using inulin clearance a more accurate method for Asian XXXX ?

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity8 :: ('MESH:D007674', 'Disease') :: ['MDRD', 'Modification of Diet in Renal Disease'] @entity740 :: ('MESH:D051436', 'Disease') :: ['Chronic Kidney Disease']
@entity1 :: (9606,Species) :: ['patients']
