OBJECTIVES: We sought to find out whether @entity452 echocardiography (DbE) could provide independent prediction of total and cardiac mortality, incremental to clinical and angiographic variables. BACKGROUND: Existing outcome studies with DbE have examined composite end points, rather than @entity204 , over a relatively short follow-up. Clinical and stress data were collected in 3,156 @entity1 (age 63 +/- 12 years, 1,801 @entity1 ) undergoing DbE. Significant stenoses (>50% diameter) were identified in 70% of 1,073 @entity1 undergoing coronary angiography. Total and cardiac mortality were identified over nine years of follow-up (mean 3.8 +/- 1.9). Cox models were used to analyze the effect of @entity63 and other variables, independent of other determinants of mortality. RESULTS: The @entity452 echocardiogram was abnormal in 1,575 @entity1 (50%). @entity204 occurred in 716 @entity1 (23%), 259 of whom (8%) were thought to have died from cardiac causes. @entity1 with normal DbE had a total mortality of 8% per year and a cardiac mortality of 1% per year over the first four years of follow-up. @entity63 and the extent of abnormal wall motion were independent predictors of @entity204 , together with age and @entity712 . In sequential Cox models, the predictive power of clinical data alone (model chi-square 115) was strengthened by adding the resting left ventricular function (model chi-square 138) and the results of DbE (model chi-square 181). In the subgroup undergoing coronary angiography, the power of the model was increased to a minor degree by the addition of coronary anatomy data. CONCLUSIONS: @entity452 echocardiography is an independent predictor of @entity204 , incremental to other data. While a normal @entity452 echocardiogram predicts low risk of @entity204 (on the order of 1% per year), this risk increases with the extent of abnormal wall motion at rest and stress.

Prediction of mortality using XXXX echocardiography.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['Dobutamine', 'dobutamine'] @entity63 :: ('MESH:D007511', 'Disease') :: ['Ischemia', 'ischemia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['Death', 'cardiac death', 'death']
@entity452 :: (MESH:D004280,Chemical) :: ['dobutamine']
