@entity1068 is one of the most widely used and abused drugs, increasing lipid levels in @entity1 and experimental animals. Heating of oil rich in @entity1474 ( @entity5204 ) produces various lipid peroxidative end products that can aggravate the pathological changes produced by @entity1068 . In the present communication, the effect of Cuminum cyminum was investigated on @entity167 and thermally oxidized oil induced hyperlipidaemia. The results showed increased activity of @entity492 transaminase (AST), alkaline phosphatase (ALP) and @entity5428 transferase (GGT) and increased levels of @entity165 , @entity1674 and phospholipids in the plasma of @entity35 given @entity167 , thermally oxidized oil and @entity167 +thermally oxidized oil when compared with the normal control group. The levels of tissue (liver and kidney) @entity165 and @entity1674 were increased significantly in @entity35 groups given @entity167 , thermally oxidized oil and @entity167 +thermally oxidized oil when compared with the normal control @entity35 . The levels were decreased when cumin was given along with @entity167 and thermally oxidized oil. The level of phospholipids decreased significantly in the liver and kidney of groups given @entity167 , thermally oxidized oil and @entity167 +thermally oridized oil when compared with the normal control @entity35 . The level increased when cumin was administered along with @entity167 and thermally oxidized oil. The activity of @entity36316 and C increased significantly in the liver of groups given @entity167 , thermally oxidized oil and @entity167 +thermally oxidized oil when compared with the normal control @entity35 , whereas the activity was decreased with the cumin treatment. The results obtained indicate that cumin can decrease the lipid levels in @entity167 and thermally oxidized oil induced hepatotoxicity.

Therapeutic role of Cuminum cyminum on XXXX and thermally oxidized sunflower oil induced toxicity.

@entity1 :: ('9606', 'Species') :: ['humans'] @entity5204 :: ('CHEBI:26208', 'Chemical') :: ['PUFA'] @entity5428 :: ('CHEBI:24190', 'Chemical') :: ['gamma glutamyl'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity1474 :: ('MESH:D005231', 'Chemical') :: ['polyunsaturated fatty acids'] @entity492 :: ('CHEBI:29995', 'Chemical') :: ['aspartate'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity36316 :: ('288025(Tax:10116)', 'Gene') :: ['phospholipase A'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['Ethanol', 'ethanol'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity1068 :: (MESH:D000431,Chemical) :: ['ethanol']
