Radio frequency (RF) current has been used successfully to ablate normal @entity1 tissue. To further investigate the clinical application of this modality in @entity5 we studied the potential of using RF percutaneously to destroy experimental @entity96 . Thirty five outbred albino @entity95 underwent liver VX2 @entity5 direct-implantation during open surgery. After 21 days ultrasonography was performed revealing @entity5 presence and size. A shielded RF needle was designed so that it could be inserted percutaneously through an introducing needle, and an electrical insulation shield covering the RF needle could be retracted to control the length of the exposed RF needle inside the tissue. Twenty two days after @entity5 implantation RF was applied via the aforementioned needle using a ZoMed International RF generator. In one group of @entity95 the procedure was performed under direct vision during open surgery and on the other group treatment was applied percutaneously, guiding the needle by @entity5 palpation. @entity95 were killed 3 days later and pathology revealed 4 to 25 mm intratumoral RF induced lesions. A direct relation was found between lesion size, power and duration of RF application (At 7.5 W, r = 0.48, p = 0.032). Based on our preliminary results we may conclude that RF may have clinical application in the near future for percutaneous @entity5 control in parenchymal organs.

Percutaneous ablation of @entity96 in XXXX using low radio frequency energy.

@entity1 :: ('9606', 'Species') :: ['human'] @entity95 :: ('9986', 'Species') :: ['Rabbits', 'rabbits'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'local tumor', 'tumors'] @entity96 :: ('MESH:D008113', 'Disease') :: ['liver tumors']
@entity95 :: (9986,Species) :: ['rabbits']
