UNASSIGNED: Numerous studies have reported an association between fine particulate matter (PM2.5) and @entity1 health. Often these relationships are influenced by environmental factor that varies spatially and/or temporally. To our knowledge, there are no studies in Canada that have considered energy generation and fuel sales as PM2.5 effects modifiers. Determining exposure and disease-specific risk factors over space and time is crucial for disease prevention and control. In this study, we evaluated the association of PM2.5 with @entity6 , @entity565 , and @entity101 ( @entity101 ) incidence in Canada. Then we explored the impact of the energy generation and fuel sales on association changes. We fit an age-period-cohort as the study design, and we applied an over-dispersed Poisson regression model to estimate the risk. We conducted a sensitivity analysis to explore the impact of variation in clean energy rates and fuel sales on outcomes changes. The study included 117 health regions in Canada between 2007 and 2014. Our findings showed strong association of PM2.5 with @entity6 , @entity565 , and @entity101 incidence. A two-year increase of 10 g/m(3) in PM2.5 was associated with an increased risk of 5.34% (95% CI: 2.28%; 12.53%) in @entity6 incidence, 2.24% (95% CI: 0.93%; 5.38%) in @entity565 incidence, and 8.29% (95% CI: 3.44%; 19.98%) in @entity101 incidence. Our sensitivity analysis findings suggest higher risks of @entity6 , @entity565 and @entity101 incidence when there is low clean energy generation. On the other hand, we found lower risk when we considered high rate of clean energy generation. For example, considering only @entity6 incidence, we found that the risk in health regions with low rates of clean electricity is approximately 700% higher than the risk in health regions with high rates of clean electricity. Furthermore, our analysis suggested that the risk in regions with low fuel sales is 66% lower than the risk is health regions with low rates of clean electricity. Our study provides support for the creation of effective environmental health public policies that take into account the risk factors present in Canadians health regions.

Association of PM2.5 with XXXX , @entity565 , and high blood pressure incidence in Canada: A spatiotemporal analysis of the impacts of the energy generation and fuel sales.

@entity1 :: ('9606', 'Species') :: ['human'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity101 :: ('MESH:D006973', 'Disease') :: ['High Blood Pressure', 'HBP'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes']
