Object The presentation for @entity1 with @entity2758 ( @entity2758 ) is often @entity932 ; for @entity1 , this frequently occurs during the prime childbearing years. Although previous studies have addressed the risk for @entity548 during pregnancy, such studies have not assessed the risk for @entity548 among @entity1 who become pregnant during the latency interval between stereotactic radiosurgery (SRS) and documented obliteration of the lesion. The authors sought to evaluate the risk for @entity548 in @entity1 who become pregnant during the latency interval after SRS. Methods This single-institution retrospective analysis reviewed the authors' experience with Gamma Knife SRS during 1987-2012. During this time, 253 @entity1 of childbearing age (median age 30 years, range 15-40 years) underwent SRS for @entity7026 . The median target volume was 3.9 cm(3) (range 0.1-27.1 cm(3)), and the median marginal dose was 20 Gy (range 14-38 Gy). For all @entity1 , the date of @entity7026 was recorded and the latency interval was calculated. Information about subsequent pregnancies and/or @entity548 events during the latency interval was retrieved from the medical records and supplemented by telephone contact. Results @entity7026 was confirmed by MRI or angiography at a median follow-up time of 39.3 months (range 10-174 months). There were 828.7 @entity1 -years of follow-up within the latency interval between SRS and the date of confirmed @entity7026 . Among nonpregnant @entity1 , 20 @entity548 occurred before @entity7026 , yielding an annual @entity548 rate of 2.5% for nonpregnant @entity1 during the latency interval. Among @entity1 who became pregnant during the latency interval, 2 @entity548 occurred over the course of 18 pregnancies, yielding an annual @entity548 rate of 11.1% for @entity1 who become pregnant during the latency interval. For the 2 pregnant @entity1 who experienced @entity548 , the @entity548 occurred during the first trimester of pregnancy. Conclusions The authors present the first series of data for @entity1 with @entity7026 who became pregnant during the latency interval after SRS. @entity548 during the latency interval occurred at an annual rate of 2.5% for nonpregnant @entity1 and 11.1% for pregnant @entity1 . The data suggest that pregnancy might be a risk factor for @entity548 during the interval between SRS and @entity7026 . However, this suggestion is not statistically significant because only 18 @entity1 in the study population became pregnant during the latency interval. To mitigate any increased risk for @entity548 , @entity1 should consider deferring pregnancy until treatment conclusion and @entity7026 .

@entity548 during pregnancy in the latency interval after stereotactic radiosurgery for XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity7026 :: ('MESH:D002538', 'Disease') :: ['intracranial AVM', 'intracranial AVMs', 'AVM obliteration'] @entity932 :: ('MESH:D020300', 'Disease') :: ['intracranial hemorrhage'] @entity2758 :: ('MESH:D001165', 'Disease') :: ['arteriovenous malformations', 'AVMs'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage', 'bleeding', 'Hemorrhage', 'AVM hemorrhage', 'hemorrhages']
@entity2758 :: (MESH:D001165,Disease) :: ['arteriovenous malformations']
