@entity56 to a variety of sensory stimuli is a feature of persistent @entity74 ( @entity74 ). However, little is known about sensory disturbances from the time of injury until transition to either recovery or symptom persistence. Quantitative sensory testing (pressure and thermal @entity158 thresholds, the brachial plexus provocation test), the sympathetic vasoconstrictor reflex and @entity458 (GHQ-28) were prospectively measured in 76 @entity7125 subjects within 1 month of @entity130 , 3 and 6 months @entity130 . Subjects were classified at 6 months @entity130 using scores on the Neck Disability Index: recovered (<8), mild @entity158 and disability (10-28) or moderate/severe @entity158 and disability (>30). Sensory and sympathetic nervous system tests were also measured in 20 control subjects. All @entity7125 groups demonstrated local mechanical @entity1931 in the cervical spine at 1 month @entity130 . This @entity1931 persisted in those with moderate/severe symptoms at 6 months but resolved by 2 months in those who had recovered or reported persistent mild symptoms. Only those with persistent moderate/severe symptoms at 6 months demonstrated generalised @entity56 to all sensory tests. These changes occurred within 1 month of injury and remained unchanged throughout the study period. Whilst no significant group differences were evident for the sympathetic vasoconstrictor response, the moderate/severe group showed a tendency for diminished sympathetic reactivity. GHQ-28 scores of the moderate/severe group were higher than those of the other two groups. The differences in GHQ-28 did not impact on any of the sensory measures. These findings suggest that those with persistent moderate/severe symptoms at 6 months display, soon after injury, generalised @entity56 suggestive of changes in central @entity158 processing mechanisms. This phenomenon did not occur in those who recover or those with persistent mild symptoms.

Sensory @entity56 occurs soon after XXXX and is associated with poor recovery.

@entity1931 :: ('MESH:D006930', 'Disease') :: ['hyperalgesia'] @entity458 :: ('MESH:D020018', 'Disease') :: ['psychological distress'] @entity7125 :: ('MESH:D014911', 'Disease') :: ['whiplash'] @entity56 :: ('MESH:D004342', 'Disease') :: ['Hypersensitivity', 'hypersensitivity'] @entity74 :: ('MESH:D030342', 'Disease') :: ['WAD', 'whiplash associated disorders'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity130 :: ('MESH:D014947', 'Disease') :: ['injury and then 2', 'post-injury']
@entity7125 :: (MESH:D014911,Disease) :: ['whiplash injury']
