UNASSIGNED: The @entity1641 gamma herpesviruses 2 and 5 ( @entity13444 and -5) have frequently been observed in the @entity1641 population and until recently presumed low to nonpathogenic. However, recent reports linking presence of @entity1641 gamma herpesviruses with clinical signs of mild to severe @entity358 , suggest that the role of these viruses in @entity1576 and poor performance syndrome is still unclear. Moreover, baseline data regarding the temporal pattern of shedding of @entity13444 and @entity13444 within stables and within individual actively racing @entity1641 have been lacking. In a prospective longitudinal study, we followed elite racing Standardbred trotters at monthly intervals for 13 months, to investigate whether the amount of @entity13444 and @entity13444 shedded in nasal secretions varied over time within and between individual @entity1641 . Sixty-six elite @entity1641 were investigated by analyzing nasal swabs and serum samples, a health check and evaluation of athletic performance monthly during the study period. Nasal swabs were analyzed with two newly developed qPCR assays for @entity13444 and @entity13444 , respectively. Of 663 samples, 197 (30%) were positive for @entity13444 and 492 (74%) positive for @entity13444 . Furthermore, 176 (27%) of the samples were positive for both @entity13444 and @entity13444 simultaneously. There was considerable variation in the amount and frequency of shedding of @entity13444 and @entity13444 within and between individual @entity1641 . Viral load varied seasonally, but neither @entity13444 nor @entity13444 viral peaks were associated with clinical @entity1576 and/or poor performance in racing Standardbred trotters.

Viral load of XXXX herpesviruses 2 and 5 in nasal swabs of actively racing Standardbred trotters: Temporal relationship of shedding to clinical findings and poor performance.

@entity1641 :: ('9796', 'Species') :: ['horses', 'equine'] @entity13444 :: ('12657', 'Species') :: ['EHV-2', 'EHV-5'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory disease'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung disease']
@entity1641 :: (9796,Species) :: ['equine']
