OBJECTIVE: To determine the incidence of @entity154 of the urinary tract in Colombia and study their association with maternal risk factors. METHODS: We performed a register based, case control study using the data from the ECLAMC (Colaborative latinoamerican Study for @entity600 ) in Colombia, between June, 2001 and December, 2004. Positive Registries for any @entity5450 were selected. Calculations for the incidence of each abnormality were done. Odds ratio were estimated for 11 maternal variables. RESULTS: 83 positive registries were found. The established incidence was 0.43%. These anomalies accounted for 9.4% of the @entity600 . The obtained rate (x 10,000 births) for @entity154 was: @entity2650 17.7; chryptorchidism 13.3; @entity3041 2.6; @entity8 .6; undeterminate sex 2.6; unilateral renal agenesis 1.3; micropenis 1.9; bilateral renal agenesis 0.7; patent urachus 0.3. The risk for @entity8 increased with @entity600 , odds ratio OR= 3.66; 95% IC [1.13 - 13.82] and maternal chronic disease OR = 6, 18; 95% CI [1.09 - 34.98]. A deterministic association was found with consanguinity between the parents. The positive associations for @entity790 were: low birth weight OR = 4.07; 95% CI [2.00 - 8.25], @entity600 OR= 3.80; 95% CI [1.87 - 7.72], presence of malformated individuals in the family OR = 2.30; 95% CI [1.02 - 5.25], and smoking during pregnancy OR = 5.36; CI [1.01 - 28.51]. A deterministic association was found with @entity167 ingestion during pregnancy. CONCLUSIONS: The prevalence of anomalies of the urinary tract in Colombia is considerably lower in comparison with European and North American statistics. The birth weight is the most important risk factor for anomalies like @entity2650 and chriptorchidism. Consanguinity between the parents and @entity167 ingestion during the pregnancy are determinant on the risk for @entity8 , respectively. Variables like smoking during pregnancy and chronic maternal disease must be deeply explored in the future to determine their role in the etiology of these defects.

[ XXXX : epidemiological description and associated risk factors in Colombia 2001-2004].

@entity154 :: ('MESH:D000013', 'Disease') :: ['congenital anomalies', 'each anomaly'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal defects', 'cystic renal disease 2', 'renal and genital anomalies'] @entity2650 :: ('MESH:D007021', 'Disease') :: ['hypospadias'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity5450 :: ('MESH:D014570', 'Disease') :: ['urological anomaly'] @entity3041 :: ('MESH:D006869', 'Disease') :: ['hydronephrosis'] @entity600 :: ('MESH:D000014', 'Disease') :: ['preterm birth', 'total of malformations', 'Congenital Malformations'] @entity790 :: ('MESH:D014564', 'Disease') :: ['genital defects']
@entity154 :: (MESH:D000013,Disease) :: ['Congenital urological anomalies']
