OBJECTIVE: @entity979 ( @entity979 ) in adults are rare, and knowledge regarding their optimal management and treatment outcome is limited. Herein, we present the clinical results of our series of @entity979 other than @entity979 managed by stereotactic radiosurgery (SRS) at upfront setting. METHODS: Between 1997 and 2014, nine consecutive adult @entity1 with the diagnosis of @entity979 , either @entity979 or @entity979 of intermediate differentiation, were treated with SRS. There were 6 @entity1 and 3 @entity1 . The median age was 39 years (range, 31-53 years). All of the @entity1 presented with symptoms of @entity1276 . Endoscopic third ventriculostomy and biopsy was done for initial management. After histologic diagnosis, @entity1 were treated with Gamma Knife with the mean dose of 13.3 Gy (n=3) or fractionated Cyberknife with 32 Gy (n=6). RESULTS: After a mean follow-up of 78.6 months (range, 14-223 months), all @entity1 were alive and all of their @entity5 were locally controlled except for one instance of cerebrospinal fluid seeding metastasis. On magnetic resonance images, @entity5 size decreased in all @entity1 , resulting in complete response in 3 @entity1 and partial response in 6. One @entity1 had experienced temporary @entity2414 after SRS, which improved spontaneously. CONCLUSION: SRS is effective and safe for @entity979 in adults and can be considered as a useful alternative to surgical resection at upfront setting.

Upfront Stereotactic Radiosurgery for XXXX in Adults.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity1276 :: ('MESH:D006849', 'Disease') :: ['hydrocephalus'] @entity979 :: ('MESH:D010871', 'Disease') :: ['pineoblastomas', 'pineal parenchymal tumor', 'PPTs', 'Pineal parenchymal tumors', 'pineocytoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity2414 :: ('MESH:D008569', 'Disease') :: ['memory impairment']
@entity979 :: (MESH:D010871,Disease) :: ['Pineal Parenchymal Tumors']
