OBJECTIVE: To determine the impact of multispectral digital @entity272 analysis on German dermatologist biopsy decisions of atypical @entity272 . DESIGN: @entity1 were shown high-resolution clinical images of 12 atypical @entity272 previously analyzed by multispectral digital @entity272 analysis. @entity1 were asked if they would biopsy the lesion based on clinical images and high-resolution dermoscopy images and again when subsequently shown multispectral digital @entity272 analysis probability information. SETTING/ @entity1 : Forty-one dermatologists at a @entity1489 conference in Germany in September 2014. MEASUREMENTS: Sensitivity, specificity, diagnostic accuracy, percent biopsying all @entity320 , and overall biopsy rates. RESULTS: Sensitivity for the detection of @entity320 following clinical evaluation was 64 percent. After receipt of multispectral digital @entity272 analysis probability information, sensitivity decreased nonsignificantly to 62 percent. Specificity with clinical evaluation was 57 percent and increased to 73 percent using multispectral digital @entity272 analysis. Overall biopsy accuracy increased from 60 percent with clinical evaluation to 68 percent with multispectral digital @entity272 analysis. The percentage of low-grade @entity6349 chosen for biopsy decreased from 43 percent after clinical evaluation to 27 percent with multispectral digital @entity272 analysis. Finally, the overall percentage of lesions biopsied decreased from 52 percent with clinical evaluation to 42 percent after multispectral digital @entity272 analysis. CONCLUSION: Multispectral digital @entity272 analysis can be used reliably to detect @entity320 as well as clinical evaluation. Dermatologists can confidently use multispectral digital @entity272 analysis to significantly improve specificity and reduce their overall number of biopsies while increasing overall diagnostic accuracy.

The Impact of Multispectral Digital Skin Lesion Analysis on German Dermatologist Decisions to Biopsy Atypical Pigmented Lesions with Clinical Characteristics of XXXX .

@entity1 :: ('9606', 'Species') :: ['Participants', 'PARTICIPANTS'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma', 'melanomas'] @entity1489 :: ('MESH:D012878', 'Disease') :: ['skin cancer'] @entity272 :: ('MESH:D012871', 'Disease') :: ['pigmented skin lesions', 'skin lesion'] @entity6349 :: ('MESH:D004416', 'Disease') :: ['dysplastic nevi']
@entity320 :: (MESH:D008545,Disease) :: ['Melanoma']
