@entity1851 is the prototype marker of @entity32 and has been shown to predict mortality in hemodialysis @entity1 . However, it remains uncertain as to whether a single @entity1851 level has similar prognostic significance in peritoneal dialysis @entity1 . A single high-sensitivity @entity1851 (hs-CRP) level was measured in 246 continuous ambulatory peritoneal dialysis @entity1 without active infections at study baseline together with indices of dialysis adequacy, echocardiographic parameters (left ventricular mass index, left ventricular dimensions, and ejection fraction), nutrition markers (serum albumin, dietary intake, and subjective global assessment) and biochemical parameters (hemoglobin, lipids, @entity460 , and @entity1391 ). The cohort was then followed-up prospectively for a median of 24 mo (range, 2 to 34 mo), and outcomes were studied in relation to these parameters. Fifty-nine @entity1 died (36 from cardiovascular causes) during the follow-up period. The median hs-CRP level was 2.84 mg/L (range, 0.20 to 94.24 mg/L). @entity1 were stratified into tertiles according to baseline hs-CRP, namely those with hs-CRP < or = 1.26 mg/L, 1.27 to 5.54 mg/L, and > or = 5.55 mg/L. Those with higher hs-CRP were significantly older (P < 0.001), had greater body mass index (P < 0.001), higher prevalence of @entity453 (P = 0.003), and greater left ventricular mass index (P < 0.001). One-year overall mortality was 3.9% (lower) versus 8.8% (middle) versus 21.3% (upper tertile) (P < 0.0001). @entity65 rate was 2.7% (lower) versus 5.2% (middle) versus 16.2% (upper tertile) (P < 0.0001). Multivariable Cox regression analysis showed that every 1 mg/L increase in hs-CRP was independently predictive of higher all-cause mortality (hazard ratio [ @entity712 ], 1.02; 95% CI, 1.01 to 1.04; P = 0.002) and @entity65 ( @entity712 , 1.03; 95% CI, 1.01 to 1.05; P = 0.001) in peritoneal dialysis @entity1 . Other significant predictors for all-cause mortality included age ( @entity712 , 1.07; 95% CI, 1.04 to 1.10), gender ( @entity712 , 0.49; 95% CI, 0.27 to 0.90), @entity731 ( @entity712 , 2.65; 95% CI, 1.46 to 4.80), left ventricular mass index ( @entity712 , 1.01; 95% CI, 1.00 to 1.01) and residual GFR ( @entity712 , 0.53; 95% CI, 0.38 to 0.75). Age ( @entity712 , 1.06; 95% CI, 1.02 to 1.10), history of @entity712 ( @entity712 , 3.31; 95% CI, 1.36 to 8.08), @entity731 ( @entity712 , 3.20; 95% CI, 1.43 to 7.13), and residual GFR ( @entity712 , 0.57; 95% CI, 0.38 to 0.86) were also independently predictive of @entity65 . In conclusion, a single, random hs-CRP level has significant and independent prognostic value in @entity1726 @entity1 .

Is a single time point @entity1851 predictive of outcome in peritoneal dialysis XXXX ?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity712 :: ('MESH:D006333', 'Disease') :: ['HR', 'heart failure'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic vascular disease'] @entity1726 :: ('OMIM:168600', 'Disease') :: ['PD'] @entity1391 :: ('CHEBI:26020', 'Chemical') :: ['phosphate'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular mortality', 'Cardiovascular death'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein']
@entity1 :: (9606,Species) :: ['patients']
