Acquired and inherited @entity49 are associated with @entity393 ( @entity393 ). Antithrombotic therapy could restore hemostatic balance and improve early placentation and gestational outcome. We evaluated the efficacy of @entity2120 adapted to the fertility program for prevention of @entity393 in 35 @entity1 (W) with early @entity393 and @entity49 . Previous to the diagnosis of @entity49 , they had had a total of 105 gestations of which 89 (85%) ended in early @entity393 . After diagnosis of @entity49 , 35 subsequent pregnancies were treated with @entity2120 . In 5 cases assisted reproductive techniques were necessary to achieve pregnancy due to @entity249 . In 17 W who had had at least one preclinical @entity393 , @entity2120 (20 mg/d/s.c.) was started previous to conception and adapted to the fertility program. All the @entity1 continued with the gestational regime. Eighteen W with only clinical @entity393 started @entity2120 (20 mg twice per day s.c.) after biochemical pregnancy diagnosis. During gestations heparin dose was adjusted with anti Xa test, maintaining a range between 0.3 at 0.6 u/ml. With antithrombotic therapy, 30/35 (85%) of the pregnancies ended in live birth versus 16/105 (15%) of the pregnancies without treatment (p < 0.001). These results suggest that @entity2120 adapted to the fertility program can be effective in the prevention of preclinical and clinical abortion in @entity1 with @entity49 .

[Treatment with XXXX adapted to the fertility programs in @entity1 with recurrent abortion and @entity49 ].

@entity1 :: ('9606', 'Species') :: ['women'] @entity249 :: ('MESH:D007246', 'Disease') :: ['couple infertility'] @entity49 :: ('MESH:D019851', 'Disease') :: ['thrombophilia'] @entity393 :: ('MESH:D034381', 'Disease') :: ['pregnancy loss', 'recurrent pregnancy loss', 'RPL'] @entity2120 :: ('MESH:D017984', 'Chemical') :: ['enoxaparin']
@entity2120 :: (MESH:D017984,Chemical) :: ['enoxaparin']
