@entity1011 clearance, daily urinary protein excretion, serum concentrations of thyroid hormones (TT4, TT3, fT4, fT3), TSH and @entity461 ( @entity461 ), have been measured before and after 2 or 6 months of a low protein diet supplemented with @entity1522 and ketoanalogues in 18 @entity1 affected by chronic @entity1985 without significant @entity8 . Mean @entity1011 clearance and mean serum protein concentration (79.5 +/- 13.8 ml/min and 5.4 +/- 0.6 g/dl, mean +/- S.D., respectively) did not significantly change (79.1 +/- 17.3 ml/min and 5.5 +/- 0.6 g/dl) after the diet. Mean daily urinary protein excretion (7.1 +/- 2.2 g/day basally) significantly decreased (5.5 +/- 1.9 g/day) after the diet (p less than 0.05). Mean serum TT4 concentration (5.6 +/- 1.8 micrograms/dl basally) significantly increased (6.7 +/- 2 micrograms/dl, p less than 0.05) after the diet. Mean serum TT3 concentration (106.7 +/- 28.5 ng/dl, basally) significantly increased (126.7 +/- 22.6 ng/dl) after the diet (p less than 0.01). Mean serum fT4 and fT3 concentrations (8.0 +/- 2.9 pg/ml and 4.5 +/- 1.6 pg/ml, respectively) did not significantly change (9.4 +/- 2.7 pg/ml, and 4.9 +/- 1.9 pg/ml, respectively) after the diet. In some @entity1 low basal serum concentration values of TT4, TT3, fT4, fT3 became normal after the diet. Mean serum TSH concentration (3.1 +/- 2.3 microU/ml basally), significantly decreased (1.5 +/- 1.3 microU/ml) after the diet (p less than 0.05). Mean serum @entity461 concentration (0.7 +/- 0.3 ng/ml basally) significantly decreased (0.4 +/- 0.2 ng/ml) after the diet (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Low protein supplemented diet corrects altered serum thyroid hormone and TSH concentrations in @entity1 with chronic XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1522 :: ('CHEBI:33709', 'Chemical') :: ['aminoacids'] @entity1985 :: ('MESH:D009404', 'Disease') :: ['nephrotic syndrome'] @entity8 :: ('MESH:D007674', 'Disease') :: ['impairment of renal function'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine', 'Creatinine'] @entity461 :: ('5741', 'Gene') :: ['PTH', 'parathyroid hormone']
@entity1985 :: (MESH:D009404,Disease) :: ['nephrotic syndrome']
