OBJECTIVE: Pelvic organ prolapse is often co-existant with @entity194 of the genital tract in older @entity1 who tend to prefer vaginal pessaries for prolapse. Vaginal @entity2931 therapy is used by some along with a support pessary for prolapse with no robust evidence to back this practice. We aimed to evaluate differences in complications of support pessaries for vaginal prolapse in postmenopausal @entity1 , with and without vaginal @entity172 use. STUDY DESIGN: We prospectively assessed postmenopausal @entity1 attending the urogynaecology clinic for a pessary change. We asked them about the level of discomfort during pessary change (visual analogue scale for @entity158 ), discharge, @entity548 and @entity281 . Ethics approval was not required as this was a service evaluation project. Statistical analysis for relative risk was performed, including sub-group analysis for 'ring pessary' and 'non-ring group' (Shelf, Gellhorn, Shaatz). RESULTS: Between July 2013 and December 2014, we assessed 120 postmenopausal @entity1 using support pessaries for prolapse. The mean age was 70 years; 45% of the @entity1 used vaginal @entity172 . There were no statistically significant differences in complications with or without vaginal @entity172 use, although the trend was higher amongst non-users. The 'non-ring' sub-group not using vaginal @entity172 had a higher risk of vaginal ulceration, @entity548 and discharge. CONCLUSION: Postmenopausal @entity1 may have lesser complications when using vaginal @entity172 with a support pessary for prolapse, particularly with pessaries other than the ring. An adequately powered randomised controlled trial is needed to assess conclusively whether vaginal @entity172 enhances comfort and reduces complications of support pessaries for prolapse.

Does vaginal XXXX treatment with support pessaries in vaginal prolapse reduce complications?

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity2931 :: ('CHEBI:50114', 'Chemical') :: ['oestrogen'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity172 :: (MESH:D004967,Chemical) :: ['estrogen']
