BACKGROUND AND PURPOSE: Several retrospective studies suggested that contrast extravasation on CT angiography predicts @entity1410 expansion, poor outcome, and mortality in primary @entity1779 . We aimed to determine the predictive value of contrast extravasation on multidetector CT angiography for clinical outcome in a prospective study. METHODS: In 160 consecutive @entity1 with spontaneous @entity1779 admitted within 6 hours of symptom onset, noncontrast CT and multidetector CT angiography were performed on admission. A follow-up noncontrast CT was done at 24 hours. Multidetector CT angiography images were analyzed to identify the presence of contrast extravasation. Clinical outcome was assessed by modified Rankin Scale on discharge and at 90 days. RESULTS: A total of 139 @entity1 with primary @entity1779 were included in the final analysis. Contrast extravasation occurred in 30 (21.6%) @entity1 . The presence of contrast extravasation was associated with increased @entity1410 expansion (P<0.0001), in-hospital mortality (P=0.008), prolonged hospital stay (P=0.006), poor outcome on discharge (P=0.025), increased 3-month mortality (P=0.009), and poor clinical outcome (P<0.0001). In multivariate analysis, contrast extravasation was a promising independent predictor (OR, 10.5; 95% CI, 3.2-34.7; P<0.0001) for 90-day poor clinical outcome followed by the presence of @entity548 (OR, 3.4; 95% CI, 1.5-7.7; P=0.003) and initial @entity1410 volume (OR, 1.0; 95% CI, 1.0-1.1; P=0.013). CONCLUSIONS: The presence of contrast extravasation on multidetector CT angiography in @entity1 with hyperacute-stage @entity1779 is an independent and strong factor associated with poor outcome. Any @entity1 with @entity1779 with such sign on multidetector CT angiography should be monitored intensely and treated accordingly.

Contrast extravasation on computed tomography angiography predicts clinical outcome in primary XXXX : a prospective study of 139 cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['intracerebral hemorrhage'] @entity548 :: ('MESH:D006470', 'Disease') :: ['intraventricular hemorrhage']
@entity1779 :: (MESH:D002543,Disease) :: ['intracerebral hemorrhage']
