BACKGROUND: @entity957 (SCC) is a rare complication of @entity3179 . So far, little is known about its pathophysiology and clinical behavior. Initiated by the working group " @entity130 " (AGW) of the German Society of Dermatology (DDG), it is the objective of the current Marjolin registry to collect cases of SCC arising in @entity3179 , in order to evaluate diagnostic characteristics. @entity1 AND METHODS: All members of the AGW received questionnaires inquiring about basic @entity1 data, @entity1066 characteristics, and therapy conducted. RESULTS: From 2010 to 2013, 30 @entity1 (20 @entity1 , 10 @entity1 ) from six tertiary wound care centers were registered. Mean age was 76.17 years. The average duration of @entity3179 prior to SCC diagnosis was 15.93 years. Suspicious wound characteristics primarily included: @entity158 (n = 3), therapy resistance (n = 27), and fetor (n = 12) as well as clinical appearance (n = 10) with atypical morphology, nodular wound bed, and hypergranulation. CONCLUSIONS: Atypical morphology or changes in appearance as well as therapy resistance despite optimal care (6-12 weeks) should prompt physicians to take spindle-shaped, if necessary multiple and serial, biopsies. Primary risk factors for @entity5 @entity1 age and @entity1066 duration.

XXXX in @entity3179 . Data of the German Marjolin Registry and review.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients', 'patient', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant transformation include'] @entity957 :: ('MESH:D002294', 'Disease') :: ['Secondary squamous cell carcinoma'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer'] @entity3179 :: ('MESH:D014647', 'Disease') :: ['venous ulcers', 'venous leg ulcers', 'chronic venous leg ulcers'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity130 :: ('MESH:D014947', 'Disease') :: ['Wound Healing']
@entity957 :: (MESH:D002294,Disease) :: ['Squamous cell carcinomas']
