PURPOSE: @entity3575 was compared with @entity3810 / @entity2614 as an adjuvant anesthesia to @entity1875 during induction. METHODS: Two-hundred sixty-three @entity1 of American Society of Anesthesiologists physical status 1 or 2 undergoing minor surgery were randomly divided into two groups. Group F @entity1 (n = 125) received 2 microg x kg(-1) @entity3575 and 1.8 mg x kg(-1) @entity1875 , and were ventilated by mask with @entity26 . Group S @entity1 (n = 138) received 1.8 mg x kg(-1) @entity1875 , followed by inhalation of 4% @entity2614 in @entity3727 (41 x @entity1009 )) and @entity26 (21 @entity1009 )) by mask. The @entity825 was intubated exactly 2, 3, 4, or 5 min after injection of 0.1 mg x kg(-1) @entity3369 , and the conditions of endotracheal intubation were scored according to the @entity1 ' responses to laryngoscopy and endotracheal intubation. Systolic blood pressure (SBP) and heart rate (HR) were measured before and after endotracheal intubation. The cost of anesthetics was also calculated. RESULTS: No significant differences in SBP were observed between the groups throughout the induction period. HR did not change from preanesthetic values in group F. In contrast, HR in group S @entity1 increased by 9-18 beats x @entity1009 ) (bpm) after inhalation of @entity3727 / @entity2614 and further increased by 17-21 bpm following endotracheal intubation. Significant differences in HR were noticed between the groups (P < 0.001). The conditions of endotracheal intubation were similar in the two groups and were satisfactory when mask ventilation exceeded 3 min. @entity3575 was less expensive than @entity2614 / @entity3727 anesthesia when mask ventilation exceeded 3 min. CONCLUSION: From the standpoints of hemodynamics and drug cost, @entity3575 is preferable to @entity3727 / @entity2614 inhalation as an adjuvant to @entity1875 during induction, because mask ventilation for more than 3 min was required for satisfactory endotracheal intubation.

Comparison of adjuvant anesthetics for XXXX induction.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity825 :: ('MESH:D055090', 'Disease') :: ['trachea'] @entity3727 :: ('CHEBI:17045', 'Chemical') :: ['N2O'] @entity1009 :: ('966', 'Gene') :: ['min(-1'] @entity3369 :: ('MESH:D014673', 'Chemical') :: ['vecuronium'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity3810 :: ('MESH:D009609', 'Chemical') :: ['nitrous oxide'] @entity2614 :: ('MESH:C009250', 'Chemical') :: ['sevoflurane'] @entity3575 :: ('MESH:D005283', 'Chemical') :: ['fentanyl', 'Fentanyl']
@entity1875 :: (MESH:D015742,Chemical) :: ['propofol']
