PURPOSE: To evaluate the accuracy of residual microcalcifications on mammogram (MG) in predicting the extent of the @entity41 after neoadjuvant systemic treatment (NST) in @entity1 with locally advanced @entity0 and to evaluate factors affecting the accuracy of MG microcalcifications using magnetic resonance imaging (MRI) as a reference. METHODS: The @entity1 who underwent NST and showed suspicious microcalcifications on MG comprised our study population. Clinicopathologic and imaging (MG, MRI) findings were investigated. Agreement between image findings and pathology was assessed and factors affecting the discrepancy were analyzed. RESULTS: Among 207 @entity1 , 196 had @entity513 or @entity513 -in-situ (mean size, 3.78  cm). The overall agreement of residual microcalcifications on MG predicting @entity41 extents was lower than MRI in all @entity5 subtypes (intraclass correlation coefficient [ICC]  =  0.368 and 0.723, p  <  0.0001). The agreement of residual MG microcalcifications and pathology was highest in HR(+)/ @entity1722 (+) @entity5 and lowest in the @entity5 (ICC  =  0.417 and 0.205, respectively). Multivariate linear regression analysis revealed that a size discrepancy between microcalcifications and histopathology was correlated with molecular subtype (p  =  0.005). In HR(+)/ @entity1722 (-) and triple-negative subtypes, the mean extents of residual microcalcification @entity5 , and overestimation of @entity5 extent was more frequent in HR(+)/ @entity1722 (+) and HR(-)/ @entity1722 (+) @entity5 . CONCLUSIONS: The extent of microcalcifications on MG after NST showed an overall lower correlation with the extent of the pathologic @entity41 than enhancing lesions on MRI. The accuracy of @entity41 evaluation after NST with MG and MRI is affected by their molecular subtype.

Residual Mammographic Microcalcifications and Enhancing Lesions on MRI After Neoadjuvant Systemic Chemotherapy for Locally Advanced XXXX : Correlation with Histopathologic @entity41 Size.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity41 :: ('MESH:D018365', 'Disease') :: ['residual tumor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'triple-negative tumors', 'tumors', 'were smaller than residual cancer'] @entity513 :: ('MESH:D044584', 'Disease') :: ['residual invasive ductal carcinoma', 'ductal carcinoma'] @entity1722 :: ('2064', 'Gene') :: ['HER2']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Cancer']
