Our previous study identified @entity33760 as an invasion and @entity3 marker in @entity157 @entity1 . Recent document suggested RhoGTPase is required for autocrine motility factor signaling. In this study, we questioned whether there is a correlation between expression of autocrine motility factor receptor and @entity33760 . Furthermore, we questioned whether elevated expression of autocrine motility factor correlates with @entity3 and poor prognosis of @entity157 . The mRNA expression level of @entity6181 and @entity33760 were examined by RT-PCR in 25 cases of @entity409 tissues (PCLT). In addition, the correlation between the expression level of @entity6181 and clinical pathologic parameters was analyzed. Furthermore, follow-up information was collected to evaluate the prognostic value of @entity6181 for @entity157 @entity1 . Our results showed that the expression of @entity6181 and @entity33760 significantly increased in @entity157 compared with PCLT; extrahepatic metastatic lesions expressed significantly higher levels of @entity6181 and @entity33760 than corresponding intrahepatic @entity157 tissues. There is a highly significant correlation of @entity6181 expression levels with @entity5 vein invasion, number of @entity5 nodes, and @entity5 stage. Anticipatively, positive correlation was observed between mRNA expression of @entity6181 and @entity33760 gene. Furthermore, the @entity157 @entity1 with high-expression of @entity6181 had significant high recurrence/ @entity3 and shorter survival than those with low-expression of @entity6181 . Together, our findings suggested a strong correlation between the expression of @entity6181 and @entity33760 and also a correlation between overexpression of them and invasion and @entity3 of @entity157 . Furthermore, our data indicated @entity6181 as a potential prognosis for @entity157 .

Elevated expression of autocrine motility factor receptor correlates with overexpression of XXXX and indicates poor prognosis in @entity157 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6181 :: ('267', 'Gene') :: ['AMFR'] @entity33760 :: ('389', 'Gene') :: ['RhoC'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity409 :: ('MESH:D008107', 'Disease') :: ['HCC and pericarcinomatous liver'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma']
@entity33760 :: (389,Gene) :: ['RhoC']
