PURPOSE: To investigate the presence of matrix metalloproteinases (MMPs) in vitreous of @entity1 with proliferative @entity1715 (PVR). To study MMPs involved in the pathogenesis of the PVR. METHODS: Twenty-one PVR vitreous samples were from @entity1 who were performed pars plana vitrectomy ( @entity2286 ). Twenty vitreous liquid samples were from @entity1 with postoperative recurrent PVR after @entity2286 . Ten vitreous samples were normal group. The activities of @entity1476 and @entity1495 were determined by quantitative gelatinase zymography. RESULTS: @entity1476 was detected in all of PVR and normal group. Vitreous samples were obtained, whereas @entity1495 was found in 13 of 21 vitreous with preoperative PVR, average (171.52 +/- 13.17)scanning units. @entity1495 was detected in 19 of 20 vitreous with postoperative recurrent PVR, average(156.01 +/- 37.21)scanning units. CONCLUSION: @entity1476 and @entity1495 were found in the vitreous of PVR. Elevated levels of @entity1495 may play a role in the development of postoperative PVR.

[A quantitative study of matrix metalloproteinases in proliferative XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1715 :: ('MESH:D018630', 'Disease') :: ['vitreoretinopathy'] @entity1476 :: ('4313', 'Gene') :: ['MMP-2'] @entity2286 :: ('12211', 'Species') :: ['PPV'] @entity1495 :: ('4318', 'Gene') :: ['MMP-9']
@entity1715 :: (MESH:D018630,Disease) :: ['vitreoretinopathy']
