UNASSIGNED: BACKGROUND Sex differences, which may be an important variable for determining anesthetic requirements, have not been well investigated in the aspect of local anesthetic. This investigation aimed to compare the minimum local analgesic concentration (MLAC) of @entity1342 for ultrasound-guided supraclavicular brachial plexus block (US-SCB) between @entity1 and @entity1 . MATERIAL AND METHODS @entity1 aged 18-45 years undergoing elective forearm, wrist, or hand surgeries under US-SCB were divided into 2 groups according to sex. The initial concentration was 0.375% @entity1342 20 mL and the concentration for the next @entity1 was determined by the up-down technique at 0.025% intervals. Success was defined as the absence of any @entity158 in response to a pinprick in the region of all 4 terminal nerves and the skin incision within 45 min. The primary outcome was the MLAC of @entity1342 , which was estimated by the Dixon and Massey method. The analgesia duration, which was defined as the time from the end of the US-SCB injection to the time of feeling discomfort and need for additional analgesics, was observed for each @entity1 . RESULTS The MLAC of @entity1342 20 mL for US-SCB was 0.2675% (95% confidence interval [CI], 0.2512-0.2838%) in @entity1 and 0.2675% (95% CI, 0.2524-0.2826%) in @entity1 . There was no significant difference in MLAC or the analgesia duration between the 2 groups (P>0.05). CONCLUSIONS We found no significant sex-related differences in MLAC or analgesia duration of @entity1342 for US-SCB.

Lack of Sex Difference in Minimum Local Analgesic Concentration of XXXX for Ultrasound-Guided Supraclavicular Brachial Plexus Block.

@entity1342 :: ('MESH:C037663', 'Chemical') :: ['ropivacaine'] @entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patient', 'men'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity1342 :: (MESH:C037663,Chemical) :: ['Ropivacaine']
