BACKGROUND: @entity418 is the 7th most common @entity5 in Iran. The northern part of the country shows the highest incidence for this @entity5 . In this study we present some epidemiological and clinicopathological characteristics of @entity1 with @entity418 in this region. METHODS: In a cross sectional study, 238 @entity418 @entity1 were enrolled in a prospective study of neoadjuvant chemo-radiation treatment in a 4-year period (2006- 2009). In an oncology clinic their epidemiologic characteristics and clinicopathological findings were registered in a preplanned file. Data consisted of age, sex, race, occupation, residential location, smoking, addiction history, signs and symptoms, blood biochemistry profile, imaging and endoscopic findings. The data were analyzed with the SPSS software. RESULTS: The mean age of the @entity1 was (55% female) 59 years. They were mostly Fars (63%) and Turkmen (13%). Seventy two percent were residents of rural area, 20% were smokers and 22.3% were opium addict and its analogues. Only 1.3% of @entity1 consumed @entity285 . The most common presenting symptom was @entity1282 (93.7%), mainly grade III @entity1282 (53%). Location of @entity5 in esophagus was in the middle third in 53.4% and lower segment in 44.5%.Sixty five percent of the @entity1 had an abnormal esophagogram. On endoscopic evaluation the most common types of @entity5 were polypoid, vegetative and fungoid, respectively. Mean @entity5 length was 5.7 cm. The most common histology type was squamus cell @entity189 (99.1%) which was moderately differentiated in 51.3% of these @entity1 . No significant relationship was found between the grade of @entity1282 with the macroscopic type and the pathologic grade of the @entity5 in this study. CONCLUSION: @entity957 comprised more than 99% of all @entity418 in our @entity1 and this histological type is the prominent type in the Northeast of Iran. Middle esophageal segment is the major site for this type of @entity5 which unfortunately most @entity1 present with grade III. @entity2026 reflects the advanced stage of the disease.

XXXX in Northeast of Iran.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer', 'malignancy', 'tumors'] @entity957 :: ('MESH:D002294', 'Disease') :: ['Squamous cell carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['Dysphasia'] @entity418 :: ('MESH:D004938', 'Disease') :: ['Esophageal cancer', 'esophageal cancers', 'esophageal carcinoma'] @entity1282 :: ('MESH:D003680', 'Disease') :: ['dysphagia'] @entity285 :: ('D000431', 'Chemical') :: ['alcohol']
@entity418 :: (MESH:D004938,Disease) :: ['Esophageal Cancer']
