Postoperative radiotherapy (PRT) is widely advocated for @entity1 with @entity957 of the head and neck that are considered to be at high risk of recurrence after surgical resection. The aims of this study were to evaluate the treatment outcomes of PRT for @entity1 with @entity189 and to identify the value of several prognostic factors. We reviewed the records of 256 @entity1 treated for @entity957 between January 1993 and December 2005. Disease-free survival (DFS) and @entity1349 ( @entity1349 ) were estimated using the Kaplan-Meier method. Log-rank test was employed to identify significant prognostic factors for DFS and @entity1349 . The Cox proportional hazards model was applied to identify covariates significantly associated with the aforementioned endpoints. Our results showed the 3-, 5-, and 10-year DFS for all @entity1 were 69.9%, 59.5%, and 34.9%, respectively. The 3-, 5-, and 10-year @entity1349 rates were 80.8%, 68.6%, and 38.8%, respectively. Significant prognostic factors for both DFS and @entity1349 on univariate analysis were grade, primary site, T stage, N stage, overall stage, @entity1600 , overall treatment times of radiation, the interval between surgery and radiotherapy, and radiotherapy equipment. Favorable prognostic factors for both DFS and @entity1349 on multivariate analysis were lower overall stage, no cervical @entity1600 , and using 60Co as radiotherapy equipment. In conclusion, our data suggest that lower overall stage, no cervical @entity1600 , and using 60Co as radiotherapy equipment are favorable prognostic factors for DFS and @entity1349 and that reducing the overall treatment times of radiation to 6 weeks or less and the interval between surgery and radiotherapy to less than 3 weeks are simple measures to remarkably improve treatment outcome.

Treatment results and prognostic factors of XXXX undergoing postoperative radiotherapy for @entity957 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity957 :: ('MESH:D002294', 'Disease') :: ['laryngeal squamous cell carcinoma', 'squamous cell carcinomas'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['lymph node metastasis'] @entity189 :: ('MESH:D002277', 'Disease') :: ['laryngeal carcinoma'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity1 :: (9606,Species) :: ['patients']
