BACKGROUND: Endoscopic resection with the submucosal saline injection technique has been used to treat early duodenal @entity5 and @entity652 . However, indications for endoscopic treatment of these @entity5 have not been established. METHODS: We used the submucosal saline injection method to treat 14 early duodenal @entity5 and @entity652 to evaluate its safety and effectiveness. A 0.9% @entity1219 solution was injected into the submucosal layer near the @entity5 through needle forceps to elevate the @entity5 , which was then resected with electrocoagulation. Resected specimens were examined to assess depth of involvement, completeness of resection, and histologic type. Reports of early duodenal @entity5 in the Japanese literature were reviewed to analyze the relationship among @entity1600 , submucosal invasion, and @entity5 size. RESULTS: All @entity5 were completely removed "en bloc" (12 @entity5 ) or in a "piecemeal" fashion (two @entity5 ). The @entity5 was 20 mm in diameter. No serious complications occurred during or after treatment. Review of Japanese literature showed that @entity1600 did not occur when protruding or @entity5 were less than 50 mm in diameter but did occur when @entity308 , with or without marginal elevation, were more than 10 mm in diameter. CONCLUSIONS: Endoscopic resection with the submucosal saline injection technique is a safe and effective treatment for early duodenal @entity5 and @entity652 . Protruding or @entity5 less than 50 mm in diameter can be removed completely. However, because of possible @entity1600 , @entity308 with or without marginal elevation should be removed surgically.

Clinicopathologic features and endoscopic resection of duodenal adenocarcinomas and XXXX with the submucosal saline injection technique.

@entity308 :: ('MESH:D003866', 'Disease') :: ['depressed tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancers', 'largest tumor', 'elevated tumors', 'tumors'] @entity1219 :: ('CHEBI:26710', 'Chemical') :: ['NaCl'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['lymph node metastasis'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas']
@entity652 :: (MESH:D000236,Disease) :: ['adenomas']
