AIM: To analyze the efficacy and safety of dose ranges of abobotulinum toxin A (BTA) for multilevel injections into upper and lower extremity muscles in @entity1 with @entity508 forms of @entity306 ( @entity306 ). MATERIAL AND METHODS: We analyzed retrospectively multilevel BTA injections for 216 @entity1 , aged from 2 to 17 years. @entity1 received 1-6 repeated injections and complex physiotherapy. @entity1 were classified according to the GMFCS. Treatment results were evaluated with the modified Ashworth and Tardieu scales. RESULTS: Multilevel BTA injections were indicated for the most (89/8%) of the @entity1 with @entity306 , and in most of them the total dosage exceeded 30 U/kg. In the bilateral forms of @entity306 , the total dosage (U and U/kg) was higher compared to the unilateral forms. Doses for each muscle in U/kg were similar in all @entity306 forms. The total doses of BTA and the intervals between the repeated injections were stable for each @entity1 . CONCLUSION: The dose ranges suggested for @entity306 are effective and safe for the reduction of @entity508 in several functional segments of upper and lower extremities in one treatment session.

[Selection of a dose of the botulinum toxin A in XXXX forms of @entity306 ].

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'Children', 'patient'] @entity508 :: ('MESH:D009128', 'Disease') :: ['spasticity', 'spastic'] @entity306 :: ('MESH:D002547', 'Disease') :: ['spastic forms of CP', 'cerebral palsy', 'CP']
@entity508 :: (MESH:D009128,Disease) :: ['spastic']
