OBJECTIVE: To characterize the clinical, EEG, and brain imaging findings in an adult case series of @entity1 with de novo @entity159 ( @entity159 ) occurring after a @entity221 . METHODS: A retrospective study (2010-2013) was undertaken with the following inclusion criteria: (1) previously healthy adults with refractory @entity159 ; (2) @entity410 onset 0-21 days after a @entity221 ; (3) lacking evidence of infectious agents in @entity2841 ) no history of @entity410 (febrile or afebrile) or previous or concomitant @entity16 . RESULTS: Among 155 refractory @entity159 cases observed in the study period, 6 @entity1 (17-35 years old) fulfilled the inclusion criteria. @entity911 and stupor were the most common symptoms at disease onset, followed after a few days by acute repeated @entity410 that were uncountable in all but one. @entity410 consisted of focal motor/ @entity2045 with subsequent generalization. Antiepileptic drugs failed in every @entity1 to control @entity410 , with all @entity1 requiring intensive care unit admission. Barbiturate coma with burst-suppression pattern was applied in 4 out of 6 @entity1 for 5-14 days. One @entity1 died in the acute phase. In each @entity1 , we observed a reversible bilateral claustrum MRI hyperintensity on T2-weighted sequences, without restricted diffusion, time-related with @entity159 . All @entity1 had negative multiple neural antibodies testing. Four out of 5 surviving @entity1 developed @entity302 . CONCLUSIONS: This is a hypothesis-generating study of a preliminary nature supporting the role of the claustrum in postfebrile de novo @entity159 ; future prospective studies are needed to delineate the specificity of this condition, its pathogenesis, and the etiology.

@entity16 and XXXX following @entity221 .

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'participant', 'patient'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'Seizures', 'seizures'] @entity2045 :: ('MESH:D009207', 'Disease') :: ['myoclonic phenomena'] @entity221 :: ('MESH:D005334', 'Disease') :: ['febrile illness'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic disorder'] @entity911 :: ('MESH:D003221', 'Disease') :: ['Confusion'] @entity302 :: ('MESH:D004827', 'Disease') :: ['chronic epilepsy'] @entity2841 :: ('1437', 'Gene') :: ['CSF; (4'] @entity159 :: ('MESH:D013226', 'Disease') :: ['refractory status epilepticus', 'SE']
@entity159 :: (MESH:D013226,Disease) :: ['refractory status epilepticus']
