BACKGROUND: We analyzed the @entity137 and cosmetic outcomes for @entity1 who had undergone 3-dimensional conformal radiotherapy with a hypofractionated @entity1442 and identified the risk factors associated with such a @entity1442 . MATERIALS AND METHODS: A total of 143 @entity1 were treated for @entity0 (stage 0-III) with a hypofractionated radiation @entity1442 after breast-conserving surgery from 2006 to 2011. Most @entity1 received 42.4 Gy in 16 daily fractions, 2.65 Gy per fraction to the whole breast plus an additional simultaneous integrated or sequential boost to the @entity5 bed. RESULTS: The median follow-up period was 36 months. Mild @entity137 was observed in 62%; 7% of the @entity1 developed moderate @entity137 , but no grade 4 @entity137 was observed. The prevalence of @entity82 within the boost area was 5%, but no grade  >=  2 was observed. The prevalence of @entity82 of any grade was greater in the nonboost (23%) than in the boost area. Of all the @entity1 , 91% had good or excellent cosmetic outcomes. From the multivariate analysis, the incidence of epithelitis correlated with the @entity1 's treated volume (P  =  .044). The incidence of acute @entity137 correlated with the boost type to the @entity5 bed and the total treatment dose (P  = .012 and P  = .002, respectively). Also, a poor to fair cosmetic outcome was significantly associated statistically with the surgery type (P  = .05), boost type (P  = .004), and total dose (P  = .001). CONCLUSION: Delivering whole-breast irradiation with a hypofractionated @entity1442 of 42.4 Gy plus a simultaneous integrated boost to the @entity5 bed appears to be a safe and effective technique, with good cosmetic results and lower @entity137 .

Hypofractionated Breast Radiation: Shorter Scheme, Lower XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity', 'skin toxicity', 'acute skin toxicity'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['schedule']
@entity137 :: (MESH:D064420,Disease) :: ['Toxicity']
