OBJECTIVE: To study health-related quality of life responses to marked @entity353 in WHO Class II-III (body mass index (BMI) > or = 35 kg/m2) obese @entity1 . DESIGN: An 8 month randomised clinical trial with a 4 month @entity353 programme (10 weeks on a very-low-energy diet (VLED) and 17 behaviour modification visits) in the treatment group and no intervention in the control group. SUBJECTS: Nineteen @entity1 (mean age 45.9 y, mean BMI 39.3 kg/m2) in the treatment group and 19 @entity1 (47.2 y, 39.4 kg/m2) in the control group. MEASUREMENTS: Weight and questionnaires measuring health-related quality of life (RAND 36-Item Health Survey 1.0 and @entity28 -related psychosocial problems scale). RESULTS: In the treatment group, the mean (s.d.) @entity353 was 17.0 (7.4)% at the end of the 4 month therapy. At the end of follow-up, nearly 6 months after the end of VLED in the treatment group, the average maintained @entity353 was 13.9 (7.8)% of baseline weight. The control group was weight stable throughout the study. During treatment, there was only transient improvement in general health, bodily @entity158 , mental health, emotional role functioning and vitality (all increases in the scores were not statistically significant). Improvements in physical functioning, social functioning and @entity28 -related psychosocial problems were maintained until the end of follow-up. The treatment group also reported improvement in perceived health in the past year. There was only minor fluctuation in questionnaire scores in the control group. CONCLUSION: The short-term and maintained health-related quality of life effects of @entity353 may differ. Marked @entity353 in WHO Class II-III obese @entity1 leads to improvements in physical functioning, social functioning, @entity28 -related psychosocial problems, and perceived health; these improvements were maintained at 4 month post-intervention follow-up.

Health-related quality of life in WHO class II-III obese XXXX losing weight with very-low-energy diet and behaviour modification: a randomised clinical trial.

@entity1 :: ('9606', 'Species') :: ['men'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity']
@entity1 :: (9606,Species) :: ['men']
