Strenuous exercise is a potent inducer of oxidative stress, which has been suggested to be associated with disturbances in muscle homeostasis, @entity130 . There is no comprehensive or uniform view of the antioxidant status in @entity1641 . We have previously shown that moderate exercise induces protein oxidation in trotters. The aim of this study was to measure the antioxidative capacity of the @entity1641 in relation to different antioxidant components and oxidative stress markers after a single bout of moderate exercise to elucidate the mechanisms of antioxidant protection in @entity1641 . Eight clinically normal and regularly trained standard-bred trotters were treadmill-exercised for 53 min at moderate intensity. Blood samples were collected prior to and immediately after exercise and at 4 and 24 h of recovery. Muscle biopsies from the middle gluteal muscle were taken before exercise and after 4 h of recovery. Acute induction of @entity26 radical absorbance capacity (ORAC) did not prevent exercise-induced oxidative stress, which was demonstrated by increased lipid @entity8415 (LPO). Pre-exercise ORAC levels were, however, a determinant of total @entity2041 content of the blood after 4 and 24 h of recovery. Furthermore, baseline ORAC level correlated negatively with 4-h recovery LPO levels. Our results imply that @entity1641 are susceptible to oxidative stress, but a stronger antioxidant capacity may improve coping with exercise-induced oxidative stress.

XXXX radical absorbance capacity (ORAC) and exercise-induced oxidative stress in trotters.

@entity8415 :: ('CHEBI:35924', 'Chemical') :: ['hydroperoxides'] @entity1641 :: ('9796', 'Species') :: ['horse', 'horses'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity2041 :: ('MESH:D005978', 'Chemical') :: ['glutathione'] @entity130 :: ('MESH:D014947', 'Disease') :: ['fatigue and injury']
@entity26 :: (MESH:D010100,Chemical) :: ['Oxygen']
