AIM: We investigated the association between platelet indices and the severity of @entity453 ( @entity453 ) in @entity1 with @entity583 ( @entity583 ) who underwent primary percutaneous coronary intervention (PPCI). METHODS: A total of 484 consecutive @entity1 who were routinely referred to coronary angiography for @entity583 and 81 age- and gender-matched @entity1 with normal coronary arteries were included in the present study. We analyzed the relation between the platelet distribution width (PDW) and the angiographic severity of @entity453 . The SYNTAX score was used for assessing the severity of @entity453 . RESULTS: The mean platelet volume ( @entity6688 ), the plateletcrit (PCT) and the neutrophil levels were significantly higher in the @entity583 group than in the control group. @entity1 with an elevated SYNTAX score (>32) had higher PDW values. The levels of plateletcrit and the estimated glomerular filtration rate (eGFR) were lower in the high SYNTAX score group compared to the moderate-to-low SYNTAX score group. The PDW was positively correlated with age (r = 0.128, p=0.004) and SYNTAX score (r = 0.209, p<0.001). There was a mild, significant inverse association between the PDW level and the eGFR (r = -0.101, p=0.049), the mean platelet volume ( @entity6688 ) (r = -290, p<0.001) and the PCT (r = -345, p<001). Using multivariate logistic regression analysis, we found that age (OR = 1.046, 95% CI 1.013-1.079, p=0.005), @entity6 (OR = 4.779, 95% CI 2.339-9.767, p<0.001) and PDW (OR = 1.229, 95% CI 1.072-1409, p=0.003) were independent correlates of high SYNTAX score. CONCLUSION: Platelet distribution width, an inexpensive and easily measurable laboratory variable, is independently associated with high SYNTAX score.

Relation of platelet indices to severity of XXXX in @entity1 undergoing primary percutaneous coronary intervention.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST-segment-elevation myocardial infarction'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'coronary artery disease', 'coronary atherosclerosis'] @entity6688 :: ('10244', 'Species') :: ['MPV']
@entity453 :: (MESH:D003324,Disease) :: ['coronary artery disease']
