PURPOSE: To investigate blood oxygenation level-dependent (BOLD) MRI and diffusion-weighted imaging (DWI) at 3T for assessment of early @entity8 . MATERIALS AND METHODS: 34 @entity1 with a renal allograft ( @entity409 , 24; normal, 10) were prospectively enrolled. BOLD MRI and DWI were performed at 3T. R2* and apparent diffusion coefficient (ADC) values were measured in cortex and medulla of the allografts. Correlation between R2* or ADC values and estimated glomerular filtration rate (eGFR) was investigated. R2* or ADC values were compared among acute rejection (AR), @entity4295 ( @entity4295 ) and normal function. RESULTS: In all renal allografts, cortical or medullary R2* and ADC values were moderately correlated with eGFR (P<0.05). Early dysfunction group showed lower R2* and ADC values than normal function group (P<0.05). AR or @entity4295 had lower R2* values than normal allografts (P<0.05), and ARs had lower cortical ADC values than normal allografts (P<0.05). No significant difference of R2* or ADC values was found between AR and @entity4295 (P>0.05). CONCLUSION: BOLD MRI and DWI at 3T may demonstrate early functional state of renal allografts, but may be limited in characterizing a cause of early @entity8 . Further studies are needed.

Assessment of early XXXX with blood oxygenation level-dependent MRI and diffusion-weighted imaging.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal allograft dysfunction'] @entity409 :: ('MESH:D008107', 'Disease') :: ['early dysfunction'] @entity4295 :: ('MESH:D007683', 'Disease') :: ['acute tubular necrosis', 'ATN']
@entity8 :: (MESH:D007674,Disease) :: ['renal allograft dysfunction']
