@entity2647 , a strong alpha-adrenergic receptor-stimulating agent, was compared with @entity1425 in 65 @entity1 with out-of-hospital @entity1167 , in a double-blind study. The resuscitation was performed by the physician-staffed Prehospital Emergency Care Unit of Helsinki University Central Hospital. The @entity1 received either 1.0 mg of @entity2647 or 0.5 mg of @entity1425 i.v. in the treatment of fine @entity2224 , @entity1167 or electromechanical dissociation. If two doses of either drug did not restore circulation, 0.5 mg of known 0.01% @entity1425 was given i.v., maximally twice. In the @entity1425 group, which consisted of 36 @entity1 with a mean age of 61 years, 10 @entity1 (28%) were successfully resuscitated. The @entity2647 group consisted of 29 @entity1 with a mean age of 62 years. In this group nine @entity1 (31%) were successfully resuscitated. The two groups were comparable regarding their apnoea-times, and there was no difference in the need for extra @entity1425 between the groups. No adverse effects, such as @entity101 or @entity1168 , were noted in the @entity1 treated with either @entity1425 or @entity2647 , nor did the overall rate of successful resuscitation fall during the test period. It is concluded that @entity2647 seems as effective as @entity1425 in the treatment of @entity1167 , but further studies seem warranted.

Comparison of @entity1425 and XXXX in out-of-hospital cardiopulmonary resuscitation. A double-blind study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1425 :: ('MESH:D004837', 'Chemical') :: ['adrenaline'] @entity2647 :: ('MESH:D010656', 'Chemical') :: ['phenylephrine', 'Phenylephrine'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['ventricular fibrillation'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['cardiac arrest', 'asystole'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['bradycardia']
@entity2647 :: (MESH:D010656,Chemical) :: ['phenylephrine']
