Of 105 cases seen over 12 years with mean 4 years followup, there were 69 with @entity6558 ( @entity6558 ) and 36 with @entity6017 ( @entity6017 ). and in 43 this complicated another @entity2597 ( @entity2597 ). Primary @entity6558 had onset a decade later than others and most severe @entity121 occurred in @entity6017 . Earliest symptoms were @entity625 and @entity2407 with frequent @entity10632 (51%). The less than universal prevalence of elevated muscle enzymes (68%), myopathic electromyography (86%). and abnormal muscle biopsy (78%) emphasizes the need for complete evaluation in all cases. Improvement occurred in 69% overall, including all 23 given no therapy or low dose @entity288 and 59% of the remainder who received high dose @entity288 with added cytotoxics in one-quarter. Outcome was worse in older @entity1 and in those where @entity425 exceeded 4 months before diagnosis. Eight of 19 @entity204 were due to @entity5442 or its therapy which also caused considerable morbidity. Malignancy in 16 cases was temporally related to @entity5442 in half of these cases.

XXXX and other connective tissue diseases: a review of 105 cases.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2597 :: ('MESH:D003240', 'Disease') :: ['connective tissue disease', 'CTD'] @entity6017 :: ('MESH:D003882', 'Disease') :: ['dermatomyositis', 'DM'] @entity625 :: ('MESH:D001168', 'Disease') :: ['polyarthritis'] @entity5442 :: ('MESH:D009220', 'Disease') :: ['myositis'] @entity2407 :: ('MESH:D011928', 'Disease') :: ["Raynaud's phenomenon"] @entity425 :: ('MESH:D018908', 'Disease') :: ['weakness'] @entity288 :: ('MESH:D000305', 'Chemical') :: ['corticosteroids'] @entity10632 :: ('MESH:D012859', 'Disease') :: ['sicca syndrome'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths'] @entity121 :: ('MESH:D009135', 'Disease') :: ['myopathy'] @entity6558 :: ('MESH:D017285', 'Disease') :: ['PM', 'polymyositis']
@entity6017 :: (MESH:D003882,Disease) :: ['Dermatopolymyositis']
