BACKGROUND AND PURPOSE: @entity3038 are rare biphasic neoplasms of the central nervous system composed of a @entity463 ( @entity463 ) admixed with a sarcomatous component. There are conflicting reports regarding their clinical @entity146 . Four hundred and twenty-two consecutive @entity1 with @entity463 were treated at our hospital between 1980 and 1999, among them 12 @entity3038 . The goal of this study was to examine clinical features, treatment, survival and patterns of failure of @entity3038 @entity1 and to compare them with the entire group of @entity463 @entity1 . This comparison was refined by a matched pair analysis with a group of 12 @entity463 @entity1 selected for age, Karnofsky performance status, resection status, fractionation scheme and total dose (control @entity463 group). MATERIALS AND METHODS: Seven @entity3038 @entity1 were male, five female, with a median age of 56 years (range 37-76 years). The median @entity5 size was 4.5 cm (range 3-8 cm). The locations, all supratentorial, included temporal in six, parietal in five, frontal in four and occipital in one @entity1 . All @entity1 underwent @entity5 resection followed by postoperative radiation therapy. RESULTS: Median survival was 11.5 months for the @entity3038 group, 8.1 months for the entire @entity463 group (log rank test, P=0.16) and 11.0 months for the control @entity463 group (log rank test, P=0.36). All @entity3038 @entity1 had @entity5 recurrences and died due to neurologic causes within 19.3 months after radiation therapy. CONCLUSIONS: With regard to clinical features, survival and patterns of failure, @entity3038 and @entity463 cannot be distinguished clinically. Therefore, the same principles should be applied for the treatment of these @entity5 .

XXXX : a clinical study.

@entity3038 :: ('MESH:D018316', 'Disease') :: ['Gliosarcomas', 'gliosarcomas', 'gliosarcoma'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressiveness'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'local tumor', 'tumors'] @entity463 :: ('MESH:D005909', 'Disease') :: ['glioblastoma multiforme', 'GBM']
@entity3038 :: (MESH:D018316,Disease) :: ['Gliosarcoma']
