BACKGROUND: @entity161 has been associated with limited abilities to interact effectively in social situations. Face perception and ability to recognise familiar faces are critical for social interaction. @entity1 with chronic @entity161 are known to show @entity73 . Studying first-episode (FE) @entity1 allows the exclusion of confounding effects of chronicity, medication and institutionalisation in this deficit. OBJECTIVE: To determine brain (dys)functions during a face encoding and recognition paradigm in FE @entity161 . METHODS: Thirteen antipsychotic-na  ve FE @entity161 @entity1 and 13 age- and sex-matched healthy controls underwent functional magnetic resonance imaging during a face encoding and recognition paradigm. Behavioural responses were recorded on line. RESULTS: @entity1 recognised significantly fewer of previously presented faces than the controls (p = 0.008). At the neural level, both groups activated a network of regions including the fusiform area, occipital, temporal and frontal regions. In brain activity, the two groups did not differ in any region during encoding or recognition conditions (p > 0.05, corrected or uncorrected). CONCLUSIONS: Our findings show @entity73 without a significant alteration of related brain activity in FE @entity161 @entity1 . It is possible that neural changes become more strongly evident with progression of the illness, and manifest themselves as behavioural impairments during the early course.

An fMRI study of face encoding and recognition in first-episode XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impaired face recognition'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia', 'Schizophrenia']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
