In a 12-month period, metastatic @entity5 was diagnosed in eight @entity1 . Six of them presented with @entity158 mimicking toothache, @entity2956 or @entity4254 , while two showed @entity79 in the panoramic radiography, and perimandibular swelling. Anesthesia of the lower lip was the only common clinical feature. In seven of the eight @entity1 , a whole body bone scintigraphy and single photon emission computed tomography (SPECT) of the skull in combination with a whole body and SPECT anti-granulocyte (Tc-99m MAK 250/183) bone marrow scintigraphy was performed. One @entity1 did not have combined scintigraphy performed secondary to severe @entity262 . In six of the seven, the results were conclusive for a metastatic @entity79 . Biopsies confirmed three @entity1 to have a previously unrecognized primary @entity5 , one @entity1 to have previously unrecognized recurrent @entity5 , and three @entity1 to exhibit new metastatic spread of an already diagnosed @entity5 . Histology revealed @entity0 and a @entity5 of inconclusive origin. In the remaining @entity1 , combined scintigraphy suggested @entity4034 , yet biopsy revealed a prostate @entity5 @entity3 with acute inflammatory cell infiltration. Thus, the scintigraphy pattern of a hot spot in the bone scan and a @entity75 in the bone marrow scintigraphy is highly suggestive of a mandibular @entity3 , if accompanied by anesthesia of the lower lip.

Clinical manifestations and diagnostic approach to metastatic XXXX of the mandible.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast, lung, renal cancer'] @entity2956 :: ('MESH:D013705', 'Disease') :: ['temporomandibular joint disorders'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'malignancy'] @entity75 :: ('MESH:D001927', 'Disease') :: ['cold lesion'] @entity4254 :: ('MESH:D014277', 'Disease') :: ['trigeminal neuralgia'] @entity4034 :: ('MESH:D010019', 'Disease') :: ['osteomyelitis'] @entity262 :: ('MESH:D034721', 'Disease') :: ['systemic illness'] @entity79 :: ('MESH:D001847', 'Disease') :: ['osteopenic bone lesions', 'bone lesion'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
