BACKGROUND: @entity4877 , one of the key products formed when b-glucans are degraded by the microbiota in the colon, has been proposed to be important for @entity694 . @entity1160 bound to the fibre may have similar effects once it has been liberated from the fibre in the colon. Both b-glucans and @entity1160 are found in high amounts in malted @entity2247 . @entity10263 together with malt has been shown to increase the formation of @entity4877 further in @entity35 . OBJECTIVE: To investigate whether @entity10263 271, @entity6983 87002, @entity1336 HEAL 9 and 19, and Bifidobacterium infantis CURE 21 affect the levels of short-chain @entity1718 and @entity1160 in caecum and portal blood of @entity35 fed @entity2247 malt. DESIGN: The experimental diets were fed for 12 days. The daily dose of the probiotic strain was 1 10(9) colony forming units and the intake of fibre 0.82 g/day. RESULTS: The malt mostly contained insoluble fibre polymers (93%), consisting of @entity413 and @entity6122 (38-41 g/kg) and some @entity4583 (21 g/kg). The fibre polysaccharides were quite resistant to fermentation in the @entity35 , regardless of whether or not probiotics were added (25-30% were fermented). Caecal and portal levels of @entity1543 decreased in the @entity35 after the addition of @entity1336 HEAL 9 and @entity10263 271, and also the levels of @entity4877 . Viable counts of @entity10263 , Bifidobacterium and Enterobacteriaceae were unaffected, while the caecal composition of Lactobacilli was influenced by the type of strain administrated. Portal levels of @entity1160 were unchanged, but @entity2228 levels increased with @entity1336 HEAL 9 and 19 and @entity815 with @entity10263 271. CONCLUSIONS: Although the probiotic strains survived and reached the caecum, except B. infantis CURE 21, there were no effects on viable counts or in the fermentation of different fibre components, but the formation of some bacterial metabolites decreased. This may be due to the high proportion of insoluble fibres in the malt.

Prebiotic and synbiotic effects on XXXX fed malted @entity2247 with selected bacteria strains.

@entity6122 :: ('MESH:D014994', 'Chemical') :: ['xylose'] @entity2247 :: ('4513', 'Species') :: ['barley'] @entity1718 :: ('MESH:D005227', 'Chemical') :: ['fatty acids'] @entity1160 :: ('CHEBI:28300', 'Chemical') :: ['Glutamine', 'glutamine'] @entity1336 :: ('1590', 'Species') :: ['L. plantarum', 'Lactobacillus plantarum'] @entity2228 :: ('CHEBI:57305', 'Chemical') :: ['glycine'] @entity10263 :: ('47715', 'Species') :: ['Lactobacillus', 'Lactobacillus rhamnosus', 'L. rhamnosus'] @entity4583 :: ('MESH:D001089', 'Chemical') :: ['arabinose'] @entity4877 :: ('MESH:D020148', 'Chemical') :: ['Butyric acid', 'butyric acid'] @entity815 :: ('CHEBI:28044', 'Chemical') :: ['phenylalanine'] @entity6983 :: ('1597', 'Species') :: ['Lactobacillus paracasei'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity1543 :: ('MESH:D019342', 'Chemical') :: ['acetic acid'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colonic health'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity35 :: (10116,Species) :: ['rats']
