PURPOSE: The purpose of this study was to assess the influence of @entity1496 concentration on diagnostic efficacy in multi-detector-row computed tomography (MDCT) angiography of the abdominal aorta and abdominal arteries. METHODS: IRB approval and informed consent were obtained. In this double-blind trial, @entity1 were randomised to undergo MDCT angiography of the abdominal arteries during administration of @entity61846 (350 mgI/ml) or @entity23280 (400 mgI/ml). Each centre applied its own technique for delivery of contrast medium, regardless of @entity1496 concentration. Diagnostic efficacy, image quality, visualisation of the arterial wall and arterial enhancement were evaluated. A total of 153 @entity1 received @entity61846 and 154 received @entity23280 . RESULTS: The ability to reach a diagnosis was "satisfactory" to "totally satisfactory" in 152 (99.3%) and 153 (99.4%) @entity1 respectively. Image quality was rated as being "good" to "excellent" in 94.7 and 94.8% segments respectively. Similar results were observed for image quality of arterial walls (84.3 vs. 83.2%). The mean relative changes in arterial enhancement between baseline and arterial phase images showed no statistically significant differences. CONCLUSION: This study demonstrated the non-inferiority of the 350 versus 400 mgI/ml @entity1496 concentration, in terms of diagnostic efficacy, in abdominal MDCT angiography. It also confirmed the high robustness and reliability of this technique across multi-national practices.

64-Slice CT angiography of the abdominal aorta and abdominal arteries: comparison of the diagnostic efficacy of XXXX 350 mgI/ml versus @entity23280 400 mgI/ml in a prospective, randomised, double-blind multi-centre trial.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1496 :: ('MESH:D007455', 'Chemical') :: ['iodine'] @entity23280 :: ('MESH:C057937', 'Chemical') :: ['iomeprol'] @entity61846 :: ('MESH:C093233', 'Chemical') :: ['iobitridol']
@entity61846 :: (MESH:C093233,Chemical) :: ['iobitridol']
