The present study was performed to evaluate the role of neovascularization on the behavior of @entity976 as well as the contribution of endothelial cell proliferation and migration in the remodeling and expansion of the vascular network associated with angiogenesis. Fourteen @entity5 were studied, all of the adamantinomatous type. @entity2280 immunostaining, an endothelial cell marker, localized vessels within the connective tissue stroma. @entity1758 immunopositivity was apparent in the nuclei of neoplastic cells, few endothelial cells, and stromal elements. @entity1758 counts were higher in epithelial than connective tissue cells. A positive correlation was found between the number of @entity1758 immunopositive cells and microvessel density (MVD). Immunohistochemistry demonstrated that @entity9615 expression was restricted to @entity5 vasculature; the @entity5 cells were immunonegative. Only 2.5% of vessels detected with @entity2280 were immunopositive for @entity9615 . At present, no therapeutic implications can be drawn from our observations. More studies are needed to assess whether @entity9615 antagonists or drugs that arrest the cell cycle of endothelial cells can inhibit angiogenesis in @entity976 .

Angiogenesis and the growth potential of XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumors'] @entity1758 :: ('57534', 'Gene') :: ['MIB-1'] @entity976 :: ('MESH:D003397', 'Disease') :: ['craniopharyngiomas'] @entity2280 :: ('947', 'Gene') :: ['CD34'] @entity9615 :: ('3685', 'Gene') :: ['integrin alphavbeta3']
@entity976 :: (MESH:D003397,Disease) :: ['craniopharyngiomas']
