OBJECTIVES: Aim of this clinical study was to evaluate the angiosome concept with regard to the microcirculation of the foot in @entity1 with @entity63 and to evaluate its relevance by means of combined laser Doppler flowmetrie and white-light tissue spectrophotometry. . METHODS: 28 @entity1 who underwent leg revascularization in the stage of @entity63 were prospectively examined. The micro-perfusion was assessed by light guided spectrophotometry.. The measuring points were set according to the angiosome concept into direct and indirect revascularized areas of the foot. Investigations were performed pre- and post-interventionally and after 4 and 12 weeks in baseline-position as well as in an elevated position of the leg. RESULTS: Microcirculation parameters ( @entity26 saturation, blood flow, velocity) of the revascularized leg showed a significant increase in elevation and baseline position compared to the preoperative values in most analyses. No significant differences between the direct and indirect revascularized angiosome were apparent. CONCLUSION: The light guided spectrophotometry measurement proved to be feasible in terms of measuring changes in the microcirculation after leg revascularization. However our data do not support the value of the "angiosome concept" concerning the individual changes in micro-perfusion of the foot in @entity1 with @entity63 . This article is protected by copyright. All rights reserved.

The angiosome concept evaluated on the base of micro-perfusion in CLI XXXX - an O2C guided study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity63 :: ('MESH:D007511', 'Disease') :: ['critical limb ischemia']
@entity1 :: (9606,Species) :: ['patients']
