Background: @entity5 is a rare malignancy that accounts for <1% of @entity150 . There is currently no consensus on the diagnosis and management of @entity5 and there are very few reports on palliative chemotherapy for unresectable disease. We delineate the clinical features and treatment outcome of @entity5 , in particular the relevance of palliative chemotherapy in recurrent, @entity3 . Methods: The clinicopathologic variables and treatment outcome of @entity1 who were treated for @entity5 were retrospectively reviewed. Results: Among 28 eligible @entity1 , 25 had localized disease and 3 had @entity3 at initial diagnosis. All @entity1 with localized disease underwent curative resection and there was disease recurrence in 10. Out of 13 @entity1 with @entity3 either at initial diagnosis or during follow-up, the lung was the most common metastatic site (n = 5), followed by the liver, bone and peritoneum. Ten @entity1 received palliative chemotherapy. A total of 24 chemotherapeutic regimens were administered; regimens with a base of fluoropyrimidine ( @entity1487 ), @entity3907 and @entity136 were the most common. The overall response rate of all chemotherapeutic regimens was 16.7%. The @entity1487 -based regimens showed a good response, with 2 of 4 @entity1 who received these showing a partial response. One @entity5 with a partial small-cell component showed a partial response to both an etoposide-based regimen and a @entity3907 -based regimen. Conclusions: In @entity5 , curative surgery is still the recommended treatment with respect to overall survival. A @entity1487 -based chemotherapy regimen could be considered for metastatic recurrent disease.    2014 S. Karger AG, Basel.

Treatment Outcome and Relevance of Palliative Chemotherapy in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Urachal cancer', 'tumor', 'urachal cancer'] @entity3907 :: ('MESH:C080625', 'Chemical') :: ['taxane'] @entity150 :: ('MESH:D001749', 'Disease') :: ['bladder cancers'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic disease'] @entity136 :: ('MESH:C056507', 'Chemical') :: ['gemcitabine'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-FU']
@entity5 :: (MESH:D009369,Disease) :: ['Urachal Cancer']
