Normoxic and @entity519 respiration has been measured in awake @entity35 after denervation procedures designed to eliminate the regulatory input from the carotid bodies, from all chemosensory tissue supplied by the glossopharyngeal nerve (n. IX), and from abdominal chemoreceptors. Studies were made 1 day after section of the carotid sinus nerve (c.s.n.), n. IX (at a level including c.s.n.), the abdominal vagus (n. Xa) and combinations of these nerves. Results were compared with those found in normal controls. C.s.n. section led to @entity3316 in both normoxia and @entity519 , reductions in respiratory frequency being consistent and substantial, and reductions in tidal volume varying with the degree of @entity519 . By comparison, section of n. IX produced significantly greater reductions of both normoxic and @entity519 ventilation. Section of n. Xa produced no significant change in normoxic ventilation but in @entity519 produced a significant small reduction in ventilation, mostly from an effect on tidal volume. Denervation of all the associated chemosensory tissue by combined section of n. IX and n. Xa demonstrated a summation of effects but left two distinct residual responses, one to mild @entity519 , and one to severe @entity519 , both associated mainly with increases of tidal volume. The experiments demonstrate that glomus tissues at different sites in the @entity35 produce significant and distinct contributions to respiratory regulation. Denervation of all known receptors shows that significant ventilatory responses to @entity519 are still produced, either by unrevealed peripheral chemoreceptors, or by central neural mechanisms.

Respiratory effects of sectioning the carotid sinus glossopharyngeal and abdominal vagal nerves in the awake XXXX .

@entity35 :: ('10116', 'Species') :: ['rat', 'rats'] @entity519 :: ('MESH:D000860', 'Disease') :: ['hypoxic', 'hypoxia'] @entity3316 :: ('MESH:D007040', 'Disease') :: ['hypoventilation']
@entity35 :: (10116,Species) :: ['rat']
