AIM: To compare the pregnancy outcome, in particular gestational age and birth weight in @entity1 with @entity1252 ( @entity1252 ) diagnosed before and after pregnancy, and to review data on presence or absence of the antiphospholipid (aPL) antibody and flares of disease activity. METHOD: Case histories were reviewed of @entity1 with a diagnosis of @entity1252 and an obstetric event attending Monash Medical Centre (MMC) over an eight year period (1988-96). Fifty-four pregnancies in 28 @entity1 were studied, with 44 occurring after the diagnosis of @entity1252 (Group 1) and ten prior to the diagnosis of @entity1252 (Group 2). RESULTS: In Group 1 there were 25 live births (63%) with 16 full term and nine premature deliveries, 12 @entity2208 , three foetal deaths in utero and four elective terminations. In Group 2 there were seven live births (70%), two @entity2208 and one @entity204 in utero. The mean gestational age of live births was 35.8 weeks and 39.2 weeks respectively (p < 0.001). The mean birth weight of live births was 2448 g and 3030 g respectively (p < 0.023). a PL antibodies were positive in eight of 26 @entity1 tested with three live births and were negative in 18 of 26 @entity1 with 12 live births. Flares of disease activity occurred in 17 of 28 pregnancies. CONCLUSION: Pregnancy in @entity1 with a predisposition to @entity1252 have a high risk of an adverse outcome. @entity922 confers an additional risk. The mean gestational age and birth weight were significantly less in @entity1 with @entity66 . Mild flares in disease activity resulted in a favourable outcome while renal flares had a worse outcome.

Pregnancy outcome in @entity1252 ( XXXX ): a review of 54 cases.

@entity1 :: ('9606', 'Species') :: ['women'] @entity2208 :: ('MESH:D000022', 'Disease') :: ['spontaneous abortions'] @entity66 :: ('MESH:D004194', 'Disease') :: ['established disease'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE', 'systemic lupus erythematosus'] @entity204 :: ('MESH:D003643', 'Disease') :: ['foetal death'] @entity922 :: ('MESH:D013568', 'Disease') :: ['Clinical disease']
@entity1252 :: (MESH:D008180,Disease) :: ['SLE']
