The purpose of this study was to assess the results of the treatment of malignant @entity1165 guided by electrophysiologic studies. Thirty @entity1 with @entity943 , aged 56.6 +/- 14.1 years, were submitted to EP testing. The clinical presentation of @entity943 was sustained monomorphic @entity1165 in 24 (80%), non-sustained @entity1165 in three and another three were survivors of sudden @entity204 . Twenty five @entity1 (83%) had evidence of structural @entity299 and left ventricular ejection fraction was less than 40% in 16 (53%). Antiarrhythmic drugs were considered effective when sustained monomorphic @entity1165 was noninducible or significantly slowed in serial EP testing. Sustained monomorphic VT was induced in 19 @entity1 (63%) and an effective drug therapy was found in 13 (68%). In the other 11 @entity1 sustained @entity943 were not induced, although in six of them the study was done already under antiarrhythmic drugs, that were continued in the follow-up. In the six @entity1 in which an effective drug regimen could not be found and in two @entity944 survivors with primary @entity2224 and negative EP testing, an Implantable Cardioverter-Defibrillator was implanted. After 17.8 +/- 10.5 months, there was recurrence of the @entity943 in 4 (18%) of the 22 patients on antiarrhythmic drugs and half of the @entity1 with ICDs received appropriate therapy from the device. Three @entity1 (10%) died in the follow-up, of which only one due to @entity944 . We conclude that selection of optimal antiarrhythmic treatment based on the results of EP testing, is associated with @entity388 and @entity944 .

[Treatment of malignant XXXX guided by electrophysiologic study].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachyarrhythmias', 'ventricular tachycardia'] @entity944 :: ('MESH:D003645', 'Disease') :: ['sudden death'] @entity388 :: ('MESH:D020338', 'Disease') :: ['decreased episode recurrence'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['ventricular fibrillation'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart disease'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmias', 'arrhythmias', 'arrhythmia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['cardiac death']
@entity943 :: (MESH:D001145,Disease) :: ['ventricular arrhythmia']
