BACKGROUND: Many individuals with @entity161 experience remission of prominent positive symptoms but continue to experience impairments in real world functioning. Residual negative and @entity308 may have a direct impact on functioning and impair @entity1 ' ability to use the @entity73 that they possess (competence) in the real world (functional performance). METHODS: 136 individuals (100 @entity1 , 36 @entity1 ) with @entity161 were classified as having primarily positive symptoms, primarily negative symptoms, primarily @entity308 , or undifferentiated symptom profiles. Performance based measures of cognition and adaptive and interpersonal functional competence were used, along with ratings of real world behavior by high contact clinicians. Assessments were performed at baseline and at an 18-month follow-up. RESULTS: The relationships between neurocognition and capacity / performance were not moderated by symptom group ps > .091; neurocognition predicted capacity and performance for all groups ps < .001. The relationship between adaptive competence and adaptive performance was moderated by symptom group, ps < .01, such that baseline competence only predicted future performance ratings for @entity1 with primarily positive or undifferentiated symptoms, and not for individuals with primarily negative or @entity308 . This same moderation effect was found on the relationship between interpersonal competence and interpersonal performance, ps < .002. CONCLUSIONS: Residual negative and @entity308 are distinct constructs that impede the use of functional skills in the real world. @entity308 are often overlooked in @entity161 but appear to be an important factor that limits the use of functional ability in real world environments.

A Longitudinal Examination of the Moderating Effects of Symptoms on the Relationship between Functional Competence and Real World Functional Performance in XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients', 'men'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive and functional skills'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive symptoms', 'Depressive symptoms'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia']
@entity161 :: (MESH:D012559,Disease) :: ['Schizophrenia']
