OBJECTIVE: To describe the management of and outcomes in @entity1 with newly diagnosed @entity43 during 1993, 1994 and 1995 in Victoria. DESIGN AND SETTING: Retrospective cohort study conducted by surveying doctors involved in managing incident @entity43 cases identified from the population-based Victorian Cancer Registry. The survey was conducted in 1997 and the cohort was followed up until the end of 1999 to obtain at least four years of follow-up data on all @entity1 . @entity1 : All @entity1 with @entity43 diagnosed during 1993, 1994 and 1995. MAIN OUTCOME MEASURES: Reported management in terms of staging, treatment and survival. RESULTS: Management details were obtained for 84.5% (562/665) of eligible @entity1 . Median age at diagnosis was 66 years (range, 22-98 years). Surgery was the primary therapy in 77.2% of @entity1 (434/562). Only one in three @entity1 had adequate surgery, which was less likely to be performed by general gynaecologists and general surgeons than gynaecological oncologists (21.3% [35/164] v 13.3% [8/60] v 52% [105/202]). After surgery 78.6% of @entity1 (341/434) received chemotherapy, usually with @entity902 -based regimens. The overall five-year relative survival was 46% for @entity1 treated surgically; poor survival was related to increasing age, later @entity5 stage, presence of @entity843 , residual disease > 2 cm and poorer histological differentiation of the @entity5 . CONCLUSIONS: For optimal care a preoperative @entity189 antigen (CA)-125 assay, chest x-ray and pelvic ultrasound should be performed, and early referral to a multi-disciplinary unit for definitive surgery is advised. Every effort should be made to adequately stage or debulk the @entity5 . @entity1 with high-risk early-stage and advanced disease should be considered for @entity902 -based chemotherapy.

XXXX : patterns of care in Victoria during 1993-1995.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'Women', 'PATIENTS'] @entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian cancer', 'invasive epithelial ovarian cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity902 :: ('MESH:D010984', 'Chemical') :: ['platinum']
@entity43 :: (MESH:D010051,Disease) :: ['Ovarian cancer']
