OBJECTIVE: One-stage @entity2133 ( @entity2133 ) has been introduced to avoid cross-contamination between the treated and untreated regions between treatment sessions. Considering the role of inflammatory mediators in @entity2521 , the aim of the present study was to compare the effects of @entity2133 with the quadrant-wise scaling and root planing (Q-SRP) on serum levels of @entity4155 and @entity1356 in @entity1 with moderate-to-severe @entity7278 . MATERIALS AND METHODS: Twenty @entity1 with @entity7278 were selected randomly and based on inclusion criteria in each group. In order to evaluate the periodontal status, the clinical parameters of @entity548 on probing (BOP), clinical attachment level (CAL), @entity92 ( @entity92 ) and modified gingival index (MGI) were measured and recorded before treatment and at 2- and 4-month intervals after treatment. Immunologic parameters of the study such as @entity4155 and @entity1356 serum levels were determined by special laboratory kits at the same intervals. Data were analyzed by SPSS 15 statistical software. Statistical significance was defined at p<0.05. RESULTS: The results showed a decrease in the means of @entity4155 and @entity1356 serum levels in both treatment modalities, with no statistically significant differences between the two study groups at the two time intervals (p>0.05). In the evaluation of periodontal parameters, all parameters exhibited clinical improvements in both groups, with no statistically significant differences between the two study groups (p>0.05). CONCLUSION: Based on the results of the present study it was concluded that both @entity2133 and Q-SRP techniques result in improvements in periodontal indexes and decreases in the serum levels of @entity4155 and @entity1356 inflammatory mediators.

The Effects of One-Stage Full-Mouth Disinfection and Qua-drant-Wise Scaling and Root Planing on Serum Levels of XXXX and @entity1356 and Clinical Parameters (A randomized Controlled Trial Study).

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity1356 :: ('3553', 'Gene') :: ['IL-1b'] @entity7278 :: ('MESH:D055113', 'Disease') :: ['chronic periodontitis'] @entity2133 :: ('MESH:D014987', 'Disease') :: ['full-mouth disinfection technique', 'FMD'] @entity4155 :: ('3605', 'Gene') :: ['IL-17'] @entity92 :: ('MESH:D007222', 'Disease') :: ['PD', 'probing depth'] @entity2521 :: ('MESH:D010518', 'Disease') :: ['periodontitis']
@entity4155 :: (3605,Gene) :: ['IL-17']
