A new @entity16 in the @entity1573 , congenital quiver (CQ), is characterized by a continuous @entity400 . At hatching, affected chicks show a rapid @entity400 , while adult expression varies from a slight quiver to pronounced shaking. Genetic analysis showed the defect to be inherited as an autosomal recessive gene (cq) with complete penetrance. Livability of CQ birds is equivalent to that of their normal sibs. Affected females lay eggs and produce chicks; however, males are essentially sterile. Histologically, their testes show considerable cellular disorganization and a marked reduction in spermatogenic elements. Semen quality evaluations showed CQ males to be significantly inferior in respect to semen volume, sperm concentration, initial motility, and percent normal sperm. Histological examination of CQ brains revealed a number of pathological changes, including extensive @entity528 . There also is a diffuse loss of Purkinje cells in the cerebellar cortex with the remaining cell somas becoming extremely eosinophilic. In addition, many of the blood vessels throughout the white matter showed perivascular cuffing.

Congenital quiver, an inherited XXXX in the @entity1573 .

@entity1573 :: ('9031', 'Species') :: ['chicken'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological defect'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity528 :: ('MESH:D009410', 'Disease') :: ['degeneration of fiber tracts and neurons across the neuroaxis']
@entity16 :: (MESH:D009422,Disease) :: ['neurological defect']
