BACKGROUND: Morphological changes that accompany aging, such as wrinkles and @entity272 , are particularly prominent on facial skin. Recently, facial rejuvenation using the hydrofilling effect of hyaluronic acid (HA) filler has been employed for improvement of skin texture. In this study, we studied rejuvenating effects of stabilized HA ( @entity17343 Vital) through direct intradermal injections. METHODS: A total of 30 female @entity1 underwent a series of procedures on face, including three sessions at intervals of four weeks. A total of 2 mL of @entity17343 Vital was injected along the whole face using an automatic injector. Improvement of skin surface roughness, elasticity, brightness, moisture, and fine wrinkles was evaluated. @entity1 satisfaction was evaluated, and pictures of @entity1 were taken at each visit and 6 months after last treatment session. Scoring for each @entity1 was performed by three doctors according in five subjects. Moisture, oil and elasticity were measured before the procedure and before the last treatment in 10 @entity1 . RESULTS: The majority of @entity1 (77%) were satisfied with the therapeutic outcomes. Approximately 66% of @entity1 responded that the effects of this procedure persisted for longer than four months, and the majority of @entity1 (77%) wanted to undergo this procedure again and would recommend this procedure to acquaintances. Regarding doctors' evaluation, scores for improvement of skin surface roughness, elasticity, and brightness were significantly higher than those for improvement of moisture and fine wrinkle. CONCLUSIONS: Intradermal injection of HA can have a rejuvenating effect on dry and tired facial skin, especially in improvement of skin surface roughness.

Rejuvenating Effects of Facial Hydrofilling using XXXX Vital.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patient'] @entity17343 :: ('MESH:C445361', 'Chemical') :: ['Restylane'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin laxity']
@entity17343 :: (MESH:C445361,Chemical) :: ['Restylane']
