BACKGROUND: It is observed that combined liver and colon surgery especially when this includes major liver resection with Pringle maneuver (PM) performance does not have a favorable outcome. Aim of our experimental study is to investigate the impact of portal triad occlusion on the large bowel and @entity32 and potent protective effects of the variants of (PM) in the combined surgical cases. MATERIALS AND METHODS: Forty-four @entity35 were divided into four groups. In group A (control group), 1cm of the left partial colon was resected and then an end-to-end @entity254 was performed. In group B, a continuous PM for 30 minutes was performed followed by resection of 1cm of the left colon and an end-to-end @entity254 . In group C, the left colonic resection and @entity254 was performed after intermittent PM (IPM), which was 10 minutes PM followed by 5 minutes reperfusion repeated for three circles. In group D, an @entity63 preconditioning for 10 minutes was initially performed followed by 5 minutes reperfusion and then continuous PM for 30 minutes. Finally the @entity35 in group D underwent a 1cm left colonic resection and an end-to-end @entity254 . RESULTS: The percentage of @entity1960 was higher in the B group (P = 0,19). The percentage of @entity32 was not significantly higher even when we compared all "occlusion" groups (B+C+D) with the sham group. No evidence of @entity788 was found in the sham group whereas amylase and @entity9112 levels were higher in Groups B, C and D together (P = 0,0267). The comparison of group A to group B showed a significant difference (P = 0,0014) caused by continuous PM for 30 minutes, but there was no such result after IPM. CONCLUSIONS: Major liver resections are performed with PM in order to minimize intra-operative @entity190 . In the combined cases of colon surgery and major liver resections where PM is needed our results showed that IPM presents with better outcome and could be preferred compared with the other PM variants.

Variable Pringle Maneuvers and Effect on Intestinal Epithelium in XXXX . A Pilot Experimental Study in @entity35 .

@entity32 :: ('MESH:D007249', 'Disease') :: ['intra-abdominal inflammation', 'inflammation'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatitis'] @entity9112 :: ('291437(Tax:10116)', 'Gene') :: ['lipase'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity1960 :: ('MESH:D003092', 'Disease') :: ['colitis'] @entity35 :: ('10116', 'Species') :: ['rats']
@entity35 :: (10116,Species) :: ['Rats']
