PURPOSE: To investigate the incidence of @entity2118 induced by latanoprost ophthalmic solution in Japanese @entity726 @entity1 by a prospective and observer-masked study. @entity1 AND METHODS: Sixty-nine eyes of 69 @entity726 @entity1 were included. @entity1 who had undergone intraocular surgery, laser trabeculoplasty, and laser iridotomy within 12 months before enrollment, and @entity1 with history of @entity1596 and any changes in antiglaucoma drugs within 6 months before enrollment were excluded. Iridial photographs were taken by one examiner under the same conditions at 1, 3, and 6 months after the initiation of latanoprost treatment. Three @entity726 specialists, masked of @entity1 information, independently assessed the @entity2118 . Cases with @entity2118 diagnosed by three specialists were categorized as showing a definite increase in @entity2118 . RESULTS: A definite increase in @entity2118 occurred in 3.5%, 9.7%, and 35.0% of eyes within 1, 3, and 6 months of treatment, respectively. Age, gender, or concomitantly used eyedrops did not significantly influence the incidence of @entity2118 within 6 months of instillation. A reduction of intraocular pressure by latanoprost did not differ significantly between @entity1 with and without @entity2118 . CONCLUSION: The incidence of @entity2118 by latanoprost ophthalmic solution in Japanese @entity1 was higher than previously reported values in pigmented races.

Iridial pigmentation induced by latanoprost ophthalmic solution in Japanese XXXX @entity1 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'PATIENTS'] @entity1596 :: ('MESH:D014605', 'Disease') :: ['uveitis'] @entity2118 :: ('MESH:D010859', 'Disease') :: ['iridial pigmentation'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma']
@entity726 :: (MESH:D005901,Disease) :: ['glaucoma']
