OBJECTIVE: To analyze the effect of serum levels of high molecular weight @entity1254 (HMWA) on the occurrence of @entity3036 during subsequent pregnancy in @entity1 with primary pregnancy-induced @entity101 ( @entity5029 ). @entity1 AND METHODS: Thirty @entity1 with primary @entity5029 (observation group) and sixty @entity1 without primary @entity5029 (control group) were consecutively selected. ELISA was used to measure the serum levels of HMWA. The differences in the occurrence of @entity3036 during subsequent pregnancy between the two groups were compared. RESULTS: The serum levels of HMWA in the observation group were significantly lower than in the control group, and they decreased with increased severity of @entity5029 (p < 0.05). In the observation group, the gestational age was lower than that of the control group, and the occurrence of cesarean section and maternal complications were increased. The neonatal weight and Apgar scores were lower than those of the control group, and the occurrence of neonatal complications was increased. The difference was statistically significant (p < 0.05). There were no differences in the time intervals between pregnancies in the two groups. The occurrence of @entity5029 and @entity3036 during subsequent pregnancy in the observation group was significantly higher than that in the control group (p < 0.05). According to receiver operating curve analysis, the sensitivity, specificity, and accuracy of serum HMWA level in predicting the occurrence of @entity3036 during subsequent pregnancy were 85.6%, 74.8%, and 0.824 (95% CI = 0.811-0.936, p = 0.015), respectively. The critical value was 2.4 mg/l. CONCLUSIONS: Decreases of serum levels of HMWA in @entity1 with primary @entity5029 are closely related to the severity of @entity5029 and the outcome of pregnancy, which has important predictive value for the occurrence of @entity3036 during subsequent pregnancy.

Effect of serum high molecular weight XXXX level on the occurrence of @entity3036 during subsequent pregnancy in @entity1 with primary pregnancy induced @entity101 .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity5029 :: ('5177', 'Gene') :: ['PIH'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1254 :: ('9370', 'Gene') :: ['adiponectin'] @entity3036 :: ('MESH:D004461', 'Disease') :: ['eclampsia']
@entity1254 :: (9370,Gene) :: ['adiponectin']
