BACKGROUND: Subclinical @entity409 after laparoscopic cholecystectomy (LC) has been described in the literature. However, this alteration is not encountered in all @entity1 . In order to address this situation, a prospective study was conducted to investigate the effect of abdominal perfusion pressure (APP) on liver function tests after LC performed under constant intra-abdominal pressure (IAP). @entity1 AND METHODS: Of 78 @entity1 who underwent LC between May 2007 and October 2007, 40 @entity1 were eligible for the study. In all the @entity1 , six parameters of liver function ( @entity492 aminotransferase, @entity493 aminotransferase, direct @entity648 , indirect @entity648 , alkaline phosphatase, and gamma-glutamyltransferase) were assessed before and 24 hours after surgery. @entity1 who showed more than a 100% increase in at least one parameter (group 1) were compared to those who did not (group 2) regarding age, sex, body weight, body height, operation time, @entity516 time, IAP, preoperative, and intraoperative APP. RESULTS: Of the @entity1 , 37.5% showed more than a 100% increase in at least one parameter of liver function. No significant difference was found between the two groups with regard to age, sex, body weight, body height, operation time, @entity516 time, and IAP. There were significant increase in @entity6571 and ALT at 24 hours postoperatively in group 1, as compared with group 2 (P = 0.000, P = 0.001). In comparison of preoperative APP with intraoperative APP values, group 1 showed a statistically significant decrease (P = 0.000), while no difference was found in group 2. CONCLUSION: Subclinical @entity409 after LC could mostly be attributed to the negative effects of the @entity516 on hepatic blood flow. For the evaluation of @entity99 , APP may be a new criterion as a determinant of interaction with mean arterial pressure (MAP) and IAP.

What is the role of the abdominal perfusion pressure for subclinical XXXX in laparoscopic cholecystectomy?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity6571 :: ('26503', 'Gene') :: ['AST'] @entity648 :: ('MESH:D001663', 'Chemical') :: ['bilirubin'] @entity409 :: ('MESH:D008107', 'Disease') :: ['hepatic dysfunction'] @entity492 :: ('CHEBI:29995', 'Chemical') :: ['aspartate'] @entity516 :: ('MESH:D011027', 'Disease') :: ['pneumoperitoneum'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic hypoperfusion'] @entity493 :: ('CHEBI:16449', 'Chemical') :: ['alanine']
@entity409 :: (MESH:D008107,Disease) :: ['hepatic dysfunction']
