UNASSIGNED: It is unclear whether changes in mean platelet volume ( @entity6688 ) are associated with total mortality in @entity1187 . We investigated whether the change in @entity6688 predicts total mortality in @entity1 with @entity583 ( @entity583 ). We retrospectively analyzed 419 consecutive @entity1 (19 @entity1 were excluded). The remaining @entity1 were categorized as survivors (n = 351) or nonsurvivors (n = 49). Measurements of @entity6688 were performed at admission and after 24 hours. The difference between the 2 measurements was considered as the @entity6688 change (  @entity6688 ). The end point of the study was total mortality at 1-year follow-up. During the follow-up, there were 49 deaths (12.2%). Admission @entity6688 was comparable in the 2 groups. However, both @entity6688 (9.6    1.4 fL vs 9.2    1.0 fL, P = .044) and   @entity6688 (0.40 [0.10-0.70] fL vs 0.70 [0.40-1.20] fL, P < .001) at the first 24 hours were higher in nonsurvivors than survivors. In multivariate analysis,   @entity6688 was an independent predictor of total mortality (odds ratio: 1.84, 95% confidence interval: 1.28-2.65, P = .001). An early increase in @entity6688 after admission was independently associated with total mortality in @entity1 with @entity583 . Such @entity1 may need more effective antiplatelet therapy.

The Prognostic Impact of In-Hospital Change in Mean Platelet Volume in @entity1 With Non-ST-Segment Elevation XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6688 :: ('10244', 'Species') :: ['MPV'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndromes'] @entity583 :: ('MESH:D009203', 'Disease') :: ['NSTEMI', 'non-ST-segment elevation myocardial infarction']
@entity583 :: (MESH:D009203,Disease) :: ['Myocardial Infarction']
