The roles of oropharyngeal and gastric factors in satiation and @entity5463 ( @entity1831 ) secretion were examined in water-deprived @entity235 . @entity235 were prepared with chronic @entity11541 and received six treatments after 24 h of @entity1949 : rehydration with @entity2507 or extracellular fluid (ECF) with the @entity292 closed; rehydration with @entity2507 or ECF with the @entity292 open; gastric administration of @entity2507 or ECF via the @entity292 . Drinking occurred immediately after presentation and was always completed by 6 min. At the end of the 60-min period of observation, water was offered in order to assess the degree of satiety. No differences were observed between the volumes of @entity2507 or ECF consumed. However, only absorption of the water drunk produced complete satiety assessed 60 min later. Drinking @entity2507 caused a fall in plasma AVP 6 min before a detectable decline in osmolality and reached water-replete levels by 15 min after drinking. Drinking @entity2507 or ECF plus removal via the @entity292 and drinking ECF also brought about a rapid decline in plasma AVP without any change in plasma osmolality. Gastric administration of @entity2507 caused a fall in plasma AVP that coincided with the fall in osmolality, and gastric administration of ECF had no effect on plasma AVP. We conclude that oropharyngeal factors account for temporary satiety and the rapid inhibition of vasopressin secretion.

Satiety and inhibition of vasopressin secretion after drinking in dehydrated XXXX .

@entity1831 :: ('CHEBI:34543', 'Chemical') :: ['AVP'] @entity1949 :: ('MESH:D012892', 'Disease') :: ['water deprivation'] @entity5463 :: ('MESH:D001127', 'Chemical') :: ['arginine vasopressin'] @entity235 :: ('9615', 'Species') :: ['Dogs', 'dogs'] @entity2507 :: ('CHEBI:33813', 'Chemical') :: ['H2O'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula'] @entity11541 :: ('MESH:D005747', 'Disease') :: ['gastric fistulas']
@entity235 :: (9615,Species) :: ['dogs']
