AIM: To evaluate current insulin pump settings in an optimally regulated paediatric population using bolus wizard. METHODS: We used a retrospective study design to analyse data from 124 @entity1 on insulin pump therapy who had optimum HbA1c levels [<59 mmol/mol (<7.5%)] and no history of severe hypoglycaemic events. Bolus wizard settings were used to calculate the insulin to @entity1735 factors and insulin sensitivity factors. Multiple regression analysis was used to analyse the variables associated with the calculation factors. RESULTS: Insulin to @entity1735 factor varied from 276 in the youngest group to 424 in the oldest group, and increased according to age. Insulin sensitivity factor was highest in the group aged 6 to <12 years, with a value of 125. Age, amount of @entity3363 , number of boluses per day and insulin per kg were all significantly associated with both calculation factors. Furthermore, duration of insulin pump treatment was significantly associated with insulin sensitivity factor and percentage bolus/basal was significantly associated with insulin to @entity1735 factor. Gender, @entity6 duration and BMI were not associated with any of the calculation factors. CONCLUSION: Optimum insulin pump settings at pump initiation depend on both insulin requirements and use of the pump. Settings need to be individualized because the standardized calculation factors are not constant for @entity1 . There is a need to develop specific age- and insulin dose-dependent calculation factors. This article is protected by copyright. All rights reserved.

Optimum bolus wizard settings in insulin pumps in @entity1 with Type 1 XXXX .

@entity1 :: ('9606', 'Species') :: ['children'] @entity3363 :: ('MESH:D002241', 'Chemical') :: ['carbohydrates'] @entity1735 :: ('CHEBI:16646', 'Chemical') :: ['carbohydrate'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes']
