UNASSIGNED: Background and study aims: The transnasal endosheath endoscope is a new disposable technology with potential applicability to the primary care setting. The aim of this study was to evaluate the efficacy of transnasal endosheath endoscopy (TEE) for the detection of @entity355 , by comparing the diagnostic accuracy of TEE with that of standard endoscopy. @entity1 and methods: This was a prospective, randomized, crossover study performed in a single tertiary referral center. Consecutive @entity1 undergoing surveillance for @entity355 or referred for diagnostic assessment were recruited. All @entity1 were randomized to undergo TEE followed by standard endoscopy or the reverse. Endoscopy experiences and @entity1 preferences were evaluated using a questionnaire. Endoscopic and histologic diagnosis of @entity355 , and optical image quality of both endoscopic procedures, were compared. Results: A total of 21 of 25 @entity1 completed the study. TEE had sensitivity and specificity of 100% for an endoscopic diagnosis of @entity355 , and of 66.7% and 100%, respectively, for the histologic diagnosis of @entity355 . The mean optical quality of standard endoscopy was significantly better than that of TEE (7.11  0.42 vs. 4.06  0.27; P<0.0001). However, following endoscopy, @entity1 reported a significantly better experience with TEE compared with standard endoscopy (7.05  0.49 vs. 4.35  0.53; P=0.0006), with 60% preferring TEE and 25% preferring sedated standard endoscopy. Conclusions: In this study, TEE had equal accuracy for an endoscopic diagnosis of @entity355 compared with standard endoscopy, at the expense of reduced image quality and a lower yield of intestinal metaplasia on biopsy. TEE was better tolerated and preferred by @entity1 . Hence, TEE needs further evaluation in primary care as an initial diagnostic tool.

Pilot randomized crossover study comparing the efficacy of transnasal disposable endosheath with standard endoscopy to detect XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patient', 'patients'] @entity355 :: ('MESH:D001471', 'Disease') :: ["Barrett's esophagus"]
@entity355 :: (MESH:D001471,Disease) :: ['Barrett's esophagus']
