AIMS: The primary objective was to assess the occurrence rate of Medication-Related @entity2530 of the Jaw (MRONJ) after dental extraction in @entity1 treated with @entity734 ( @entity734 ) for @entity170 ( @entity170 ) or for oncological reasons. The secondary objective was to compare the extraction techniques regarding the occurrence of MRONJ. MATERIALS AND METHODS: A systematic search in PubMed/MEDLINE, EMBASE and LILACS databases was performed. Prospective studies considering @entity1 @entity1 treated with @entity734 and providing information regarding the occurrence of MRONJ after dental extraction were selected. Meta-analysis for incidence of MRONJ at the @entity1 level was performed. The effect of administration route and surgical technique on MRONJ was evaluated. RESULTS: The risk of MRONJ after dental extraction was significantly higher in @entity1 treated with @entity734 for oncological reasons (3.2%) than in those treated with per os @entity734 for @entity170 (0.15%) (p<0.0001). Dental extraction performed with adjusted extraction protocols decreased significantly MRONJ development. Potential risk indicators such as concomitant medications and pre-existing @entity4034 were identified. CONCLUSION: The risk of MRONJ after dental extraction in @entity1 treated with @entity734 exists, especially in @entity1 treated for oncologic reasons. This risk tends to decrease with adjusted extraction protocols. This article is protected by copyright. All rights reserved.

Occurrence and risk indicators of medication-related XXXX of the jaw after dental extraction: a systematic review and meta-analysis.

@entity1 :: ('9606', 'Species') :: ['human', 'patients', 'patient'] @entity4034 :: ('MESH:D010019', 'Disease') :: ['osteomyelitis'] @entity170 :: ('MESH:D010024', 'Disease') :: ['OsteoPorosis', 'OP'] @entity734 :: ('MESH:D019966', 'Disease') :: ['Anti-Resorptive Drugs', 'ARD'] @entity2530 :: ('MESH:D010020', 'Disease') :: ['OsteoNecrosis']
@entity2530 :: (MESH:D010020,Disease) :: ['osteonecrosis']
