In @entity0 , single-photon emission computed tomography/computed tomography (SPECT/CT) shows the exact anatomical location of sentinel nodes (SN). SPECT/CT mainly exposes axilla and partly exposes atypical sites of extra-axillary lymphatic drainage. The mechanism of how the atypical hot nodes are involved in lymphatic @entity3 was retrospectively investigated in the present study, particularly at the level II/III region. SPECT/CT was performed in 92 clinical stage 0-IIA @entity0 @entity1 . Sentinel lymph nodes are depicted as hot nodes in SPECT/CT. @entity1 were divided into two groups: With or without hot node in level II/III on SPECT/CT. The existence of @entity3 in level II/III was investigated and the risk factors were identified. A total of 12 @entity1 were sentinel lymph node biopsy @entity3 positive and @entity1600 ( @entity1600 ) was performed. These @entity1 were divided into two groups: With and without SN in level II/III, and nodes in level II/III were pathologically proven. In 11 of the 92 @entity1 , hot nodes were detected in level II/III. There was a significant difference in node @entity3 depending on whether there were hot nodes in level II/III (P=0.0319). Multivariate analysis indicated that the hot nodes in level II/III and lymphatic invasion were independent factors associated with node @entity3 . There were 12 SN-positive @entity1 followed by @entity1600 . In four of the 12 @entity1 , hot nodes were observed in level II/III. Two of the four @entity1 with hot nodes depicted by SPECT/CT and metastatic nodes were pathologically evident in the same lesion. Therefore, the present study indicated that the hot node in level II/III as depicted by SPECT/CT may be a risk of SN @entity3 , including deeper nodes.

Risk of node XXXX of sentinel lymph nodes detected in level II/III of the axilla by single-photon emission computed tomography/computed tomography.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['axillary lymph node dissection', 'ALND'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity3 :: (MESH:D009362,Disease) :: ['metastasis']
