OBJECTIVE: It is debated whether the @entity1316 Questionnaire (MDQ) can generate false positives by screening other disorders as @entity162 , or identify sub-threshold bipolarity. The aim is to verify if Quality of @entity73 in MQD positives in the community is due to MDQ positivity itself, or to @entity146 diagnosis associated with MDQ positivity (supporting the former hypothesis). METHOD: Community survey. Sample randomized after stratification of the adult population in the records of seven Italian regions. TOOLS: MDQ; Short Form Health Survey (SF-12); semi-structured clinical interview carried out by clinicians. RESULTS: Positives at MDQ show worsening QoL with an attributable burden of 2.8    1.8 lower than in @entity4696 (5.6    3.6, p < 0.001) or Eating Disorders (4.4    6.6, p < 0.03) and similar to @entity4697 (2.9    0.9, p = 0.44). The burden is lower in the middle-aged (25-59 years) than in the young (18-24) (4.65    4.5 vs 2.58    2.0, p=0.007) or in the elderly (>= 60) (4.12    3.2; p = 0.024). In the elderly the burden is independent from comorbid @entity146 . LIMITATIONS: This is a preliminary study based on one survey not designed to test this specific hypothesis, thus its results have a heuristic value only. CONCLUSIONS: The worsening of QoL due to positivity at MDQ is largely independent from comorbid conditions, supporting the hypothesis that MDQ positivity identifies a specific area of suffering that is "subthreshold" to the @entity146 diagnosis, and relevant for public health.

Does XXXX Questionnaire identify sub-threshold bipolarity? Evidence studying worsening of quality of life.

@entity162 :: ('MESH:D001714', 'Disease') :: ['bipolar'] @entity4697 :: ('MESH:D016584', 'Disease') :: ['Panic Disorder'] @entity146 :: ('MESH:D001523', 'Disease') :: ['psychiatric', 'psychiatric disorders'] @entity73 :: ('MESH:D003072', 'Disease') :: ['Life (QoL) impairment'] @entity1316 :: ('MESH:D019964', 'Disease') :: ['Mood Disorder'] @entity4696 :: ('MESH:D003865', 'Disease') :: ['MDD']
@entity1316 :: (MESH:D019964,Disease) :: ['Mood Disorder']
