To investigate left ventricular function and the prognosis of @entity1 with @entity384 ( @entity384 ), regional wall motion of the left ventricle of 38 @entity1 with @entity384 was observed before and during @entity452 infusion (8 micrograms/kg X min) by two-dimensional echocardiography (2DE). The left ventricle was divided into 11 segments and the severity of @entity854 ( @entity854 ) was classified into 4 grades, i.e. akinesis or dyskinesis (A), severe hypokinesis (SH), hypokinesis (H) and normokinesis (N), and numerical scores were assigned to each grade of @entity854 as follow; A: 3, SH: 2, H: 1, and N: 0. In the 38 @entity1 with @entity384 , the number of segments with @entity854 was 8.3 +/- 2.9 (mean +/- SD). Among 418 segments in the 38 @entity1 , we observed A in 71 segments, SH in 104 segments, H in 140 segments, and N in 103 segments. The @entity854 was not uniform in the left ventricle, and severe @entity854 was observed in the apex ( @entity854 score: 2.0 +/- 1.0), while the grades of @entity854 in the lateral and posterior walls were mild ( @entity854 score: 0.8 +/- 1.1) compared with those of other segments. The total sums of the @entity854 scores in 11 segments for each @entity1 (TWMAS) were significantly greater in @entity1 with severe @entity712 (New York Heart Association [NYHA] functional class III or IV) than in @entity1 with mild @entity712 (NYHA class I or II) (22.0 +/- 5.2 and 9.9 +/- 4.9, p less than 0.001). TWMAS correlated with the cardiac index (CI) (r = -0.58, p less than 0.005) and pulmonary capillary pressure (PCP) (r = 0.68, p less than 0.001). In 242 segments of 22 @entity1 , whose regional wall motion was observed before and during @entity452 administration, wall motion was improved by one grade in 82 of 170 segments with @entity854 before @entity452 infusion; i.e. regional wall motion changed from A to SH in six segments, from SH to H in 31 segments, and from H to N in 45 segments with @entity452 administration. According to the change in grade of TWMAS induced by @entity452 administration, 22 @entity1 with @entity384 were classified into two groups: a good response group (% change of TWMAS greater than or equal to 40%), and a poor response group (% change of TWMAS less than 40%). The poor response group had @entity1165 more frequently, more severe @entity712 , lower CI and higher @entity212 than the good response group.(ABSTRACT TRUNCATED AT 400 WORDS)

[Regional left ventricular function in XXXX : observation of regional left ventricular wall motion before and during @entity452 administration].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['dobutamine'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachycardia'] @entity384 :: ('MESH:D002311', 'Disease') :: ['DCM', 'dilated cardiomyopathy'] @entity212 :: ('CHEBI:8058', 'Chemical') :: ['PCP'] @entity854 :: ('MESH:D018376', 'Disease') :: ['wall motion abnormality', 'WMA']
@entity384 :: (MESH:D002311,Disease) :: ['dilated cardiomyopathy']
