Organogenesis occurs through cell division, expansion, and differentiation. How these cellular processes are coordinated remains elusive. The @entity2829 ( @entity2829 ) leaf provides a robust system to study cellular differentiation due to its distinct tissues and cell types. The narrow odd dwarf (nod) mutant displays defects at both the cellular and tissue level that increase in severity throughout growth. nod mutant leaves have reduced size due to fewer and smaller cells compared to wild type. The juvenile-to-adult transition is delayed and proximal distal-patterning is abnormal in this mutant. Differentiation of specialized cells such as those forming stomata and trichomes is incomplete. Analysis of nod-1 sectors suggests that @entity9719 plays a cell-autonomous function in the leaf. We cloned nod positionally and found that it encodes @entity69412 ( @entity69412 ), the @entity2829 MID-COMPLEMENTING ACTIVITY (MCA) homolog. @entity69412 / @entity9719 is localized to the membrane and is enriched in dividing tissues. Transcriptome analysis of nod mutants revealed overrepresentation of cell wall, hormone metabolism, and defense gene categories. We propose that @entity9719 coordinates cell activity in response to intrinsic and extrinsic cues.

The XXXX MID-COMPLEMENTING ACTIVITY Homolog @entity69412 /NARROW ODD DWARF Coordinates Organ Growth and Tissue Patterning.

@entity69412 :: ('100192784(Tax:4577)', 'Gene') :: ['CELL NUMBER REGULATOR13', 'CNR13'] @entity9719 :: ('MESH:D020191', 'Disease') :: ['NOD'] @entity2829 :: ('4577', 'Species') :: ['maize', 'Zea mays']
@entity2829 :: (4577,Species) :: ['Maize']
