BACKGROUND: A pretherapeutic staging system to design nonoperative or neoadjuvant treatments in @entity356 is required. In this study, a simple staging system based on laparoscopic findings to define a treatment algorithm was developed. METHODS: A retrospective cohort study was conducted of 151 @entity1 allocated into four stages based on laparoscopic findings. The depth of @entity5 invasion and the presence of @entity3 based on laparoscopic findings were used to construct these stages. Laparoscopic findings were compared with histopathology. RESULTS: An excellent agreement of the laparoscopy-defined depth of invasion and the surgical pathology standard was found (weighted kappa 0.85). The likelihood ratios for a positive and negative laparoscopic diagnosis of @entity3 were 40.4 and 0.015, respectively (98.5% sensitivity, 97.6% specificity). Those for positive and negative diagnosis of resectability were 2.6 and 0.03, respectively (98.4% sensitivity, 62% specificity). The laparoscopic stages presented significant prognostic value. Two-year survival was 93%, 69%, 60%, and 17%, respectively. Surgical resection was possible in 100%, 100%, 49%, and 12%, respectively. CONCLUSIONS: The proposed laparoscopic staging system is a simple and reproducibLe way for selection of a suitable therapy. It allows for adequate stratification of the main risk factors in the setting of clinical trials evaluating preoperative treatments.

The role of pretherapeutic laparoscopy in the selection of treatment for XXXX with @entity356 : a proposal for a laparoscopic staging system.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity1 :: (9606,Species) :: ['patients']
