BACKGROUND: Gaining insight in long-term health-related quality of life more than 1year after oesophagectomy will assist clinical decision-making and inform @entity1 about the long-term consequences of surgery. METHODS: In this cross-sectional study, all consecutive @entity1 who underwent oesophageal resection with gastric interposition for @entity5 at a tertiary referral centre between January 2007 and July 2012 were included. European Organization for Research and Treatment of @entity5 (EORTC) quality of life questionnaire (QLQ)-C30 and QLQ-OES18 were sent to all @entity1 alive without recurrence more than 1year after surgery. RESULTS: The questionnaires were completed by 92 of 100 @entity1 . Median duration of follow-up after surgery at completing the questionnaire was 36months (range: 12-75). Global quality of life scores were similar to a general population reference group (76  19 versus 78  17; p=0.26). However, @entity1 scored significantly worse compared to the general population reference group on physical-, role-, cognitive- and social functioning (p<0.001). Neoadjuvant therapy and minimally invasive oesophagectomy were associated with significantly better health-related quality of life (HRQL) and symptom scores (p<0.05). CONCLUSION: Global HRQL more than 1year after oesophagectomy with gastric tube reconstruction is comparable to the general Dutch background population, while specific functional and symptom scores are significantly worse. Neoadjuvant therapy and minimally invasive surgery are associated with quality of life benefits in long-term survivors.

Long-term quality of life after oesophagectomy with gastric conduit interposition for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cancer', 'cancer']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
