OBJECTIVE: To describe cognitive functions and functional outcome in young @entity1 with isolated @entity1188 . BACKGROUND: Contemporary knowledge implies a cerebellar contribution to @entity73 . Neuropsychological examination of @entity1 with selective @entity76 provides an opportunity to document the existence and nature of clinically relevant cognitive manifestations from lesions of the cerebellum. METHODS: Prospective case series. The @entity1 were assessed acutely and at 4 and 12 months after onset. Twenty-four @entity1 from a consecutive series of 105 @entity1 aged 18 to 44 years with @entity385 had a brain stem or @entity1188 . Fourteen age-matched controls were used for neuropsychological comparisons. Evaluation included MRI, angiography, and transesophageal echocardiography. @entity51 were assessed by the modified Rankin scale, NIH @entity64 scale, and maximal working capacity. A comprehensive neuropsychological battery was performed at baseline in 20 of the 24 @entity1 . RESULTS: Eighteen @entity1 had a @entity1188 . Two @entity1 had lateral medullary @entity1188 , and two isolated pontine @entity1188 . Twenty-two @entity1 had a favorable outcome according to the modified Rankin scale (grade 0-2) and the NIH scale. In contrast, 12 @entity1 were granted full or partial sick leave at the 4 months follow-up, and 10 @entity1 at 12 months. @entity1 generally performed worse than controls in various aspects of cognitive function, especially in tasks concerning working memory, the temporary storage of complex information, and @entity73 . Measures of verbal IQ (r = -0.74) and performance IQ (r = -0.78) were related to the size of the @entity1188 . The block design task performance in the early poststroke period predicted maximal working capacity at 12 months. CONCLUSIONS: @entity76 impairs central aspects of attention and visuospatial skills. In contrast, intelligence and episodic memory remain unchanged. When the lesion involves large portions of the cerebellar hemispheres, changes concerning broad areas of intelligence may occur. The prognosis is favorable for @entity51 , but @entity73 may prevent return to work.

@entity73 in young adults with XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive flexibility', 'cognitive deficits', 'cognitive behavior'] @entity51 :: ('MESH:D009461', 'Disease') :: ['Disability and neurologic dysfunction', 'neurologic dysfunction'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['cerebellar infarct', 'infratentorial infarcts', 'infarcts', 'cerebellar infarction', 'infarct'] @entity76 :: ('MESH:D002526', 'Disease') :: ['cerebellar lesions', 'Cerebellar damage'] @entity385 :: ('MESH:D002544', 'Disease') :: ['cerebral infarction']
@entity1188 :: (MESH:D007238,Disease) :: ['infratentorial infarcts']
