The aim of this study was to evaluate the effects of @entity50664 or @entity49283 on echocardiographic parameters, in @entity101 , type 2 diabetics with @entity4346 . One hundred and forty-four @entity1 were randomized to @entity50664 , 20   mg/day, or @entity49283 , 20   mg/day, in addition to @entity9886 , 100   mg/day, for 6 months. We evaluated: blood pressure, fasting plasma @entity413 (FPG), glycated hemoglobin (HbA(1c)), lipid profile, @entity1011 , estimated glomerular filtration rate (eGFR), @entity1372 , @entity972 , and acid uric. Echocardiography was performed at baseline and after 6 months. Both @entity50664 and @entity49283 decreased blood pressure. Left ventricular mass index was reduced to a greater extent with @entity49283 + @entity9886 . Interventricular septal thickness in diastole was reduced by @entity49283 + @entity9886 . Posterior wall thickness in diastole was decreased by both treatments, even if @entity49283 + @entity9886 were more effective. Ratio of peak early diastolic filling velocity to peak filling velocity at atrial contraction was increased by @entity49283 + @entity9886 , but not by @entity50664 + @entity9886 . Finally, isovolumetric relaxation and time and left atrial volume index were reduced by @entity49283 + @entity9886 , while @entity50664 + @entity9886 did not affect them. In conclusion, @entity49283 + @entity9886 provided a greater improvement of echocardiographic parameters compared to @entity50664 + @entity9886 .

XXXX or @entity50664 on Echocardiographic Parameters in @entity101 , Type 2 Diabetics with @entity4346 : A Randomized Clinical Trial.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity9886 :: ('MESH:D019808', 'Chemical') :: ['losartan'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['left ventricular hypertrophy'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity50664 :: ('MESH:C060343', 'Chemical') :: ['lercanidipine'] @entity49283 :: ('MESH:C050699', 'Chemical') :: ['barnidipine'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity49283 :: (MESH:C050699,Chemical) :: ['Barnidipine']
