UNASSIGNED: High systolic blood pressure (SBP) variability has been associated with higher risk for target-organ damage. In a cross-sectional study done in a tertiary outpatient @entity101 clinic, we compared short-term SBP variability among controlled and uncontrolled @entity101 @entity1 and evaluated the association between higher levels of SBP variability and diastolic function and @entity4346 ( @entity4346 ). @entity1 were evaluated by 24-h ambulatory blood pressure monitoring and transthoracic Doppler echocardiogram. Blood pressure (BP) variability was evaluated by the time-rate index and high variability corresponded to index values in the top quartile of distribution. Echocardiographic parameters were compared in @entity1 with and without higher BP variability within controlled and uncontrolled office BP (   140/90   mm   Hg). The analyses included 447 @entity1 with 58  12 years of age, 67% were @entity1 , 68% white, 43% current or previous smokers and 32% with @entity6 . Among the whole sample, 137 @entity1 had controlled and 310 uncontrolled BP. The 75th percentile cutoff points for the time-rate index were 0.502   mm   Hg   min(-1) and 0.576   mm   Hg   min(-1) for @entity1 with controlled and uncontrolled BP, respectively. After adjustment for confounders, the time-rate index did not differ between controlled and uncontrolled @entity1 . BP variability was not associated with @entity4346 or diastolic function in controlled and uncontrolled BP after adjustment for 24-h SBP and age. @entity1 with controlled and uncontrolled BP had similar SBP variability assessed by time-rate index, which was not associated with @entity4346 or diastolic function. These findings should be confirmed in studies with larger sample size.Journal of @entity1 @entity101 advance online publication, 15 October 2015; doi:10.1038/jhh.2015.106.

Blood pressure variability in controlled and uncontrolled blood pressure and its association with XXXX and diastolic function.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Patients', 'patients', 'Human'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['LVH', 'left ventricular hypertrophy'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'hypertensive', 'Hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus']
@entity4346 :: (MESH:D017379,Disease) :: ['left ventricular hypertrophy']
