OBJECTIVE. The purpose of this study was to assess the utility of (99m)Tc-human serum albumin @entity5531 ((99m)Tc-HSAD) SPECT in the detection of @entity1070 after @entity1028 repair. SUBJECTS AND METHODS. Fifteen @entity1 (11 @entity1 , four @entity1 ) with @entity439 sac expansion of 5 mm or greater after @entity1028 repair underwent three-phase CT, (99m)Tc-HSAD SPECT, and CT during aortography. Sensitivity calculations for three-phase CT and (99m)Tc-HSAD SPECT were performed with CT during aortography as the reference standard. The volume of each endoleak was measured with CT during aortography. Seven subjects underwent embolization with @entity7548 (NBCA)- @entity4831 (ethiodized oil, Guerbet and metallic coils. Three-phase CT and (99m)Tc-HSAD SPECT were repeated after embolization to assess their efficacy. RESULTS. Endoleaks were interpreted as perigraft radioisotope accumulation in 12 @entity1 (80.0%) on (99m)Tc-HSAD SPECT images, in 13 @entity1 (86.7%) on three-phase CT images, and in 15 @entity1 (100%) on CT during aortography. The mean endoleak volume visualized with (99m)Tc-HSAD SPECT was 8.37 cm(3) (range, 5.2-15.1 cm(3)), and the volume not visualized was 3.47 cm(3) (2.5-4.6 cm(3)), a statistically significant difference (p = 0.019). In two @entity1 , (99m)Tc-HSAD SPECT depicted @entity1070 evident at delayed phase CT during aortography but not at three-phase CT, suggesting they were slow-filling @entity1070 . Accumulation of (99m)Tc-HSAD corresponding to @entity1070 disappeared after embolization, but CT evaluation of embolization was impeded by artifacts of NBCA-Lipiodol and metallic coils. CONCLUSION. Technetium-99m-labeled HSAD SPECT proved less sensitive than three-phase CT but depicted @entity1070 with volumes 5.2 cm(3) or greater as perigraft radioisotope accumulation. Slow-filling @entity1070 can be visualized with (99m)Tc-HSAD SPECT, which can be used to evaluate the efficacy of embolization.

Utility of (99m)Tc-Human Serum Albumin Diethylenetriamine Pentaacetic Acid SPECT for Evaluating Endoleak After XXXX Repair.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity1070 :: ('MESH:D057867', 'Disease') :: ['endoleaks'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysm'] @entity7548 :: ('MESH:D004659', 'Chemical') :: ['N-butyl cyanoacrylate'] @entity4831 :: ('MESH:D004998', 'Chemical') :: ['Lipiodol'] @entity5531 :: ('MESH:D004369', 'Chemical') :: ['diethylenetriamine pentaacetic acid'] @entity1028 :: ('MESH:D017544', 'Disease') :: ['endovascular abdominal aortic aneurysm']
@entity1028 :: (MESH:D017544,Disease) :: ['Endovascular Abdominal Aortic Aneurysm']
