BACKGROUND: The aim of this study was to determine the relative role of @entity338 and right ventricular outflow tract damage in the genesis of late symptoms related to @entity1001 . METHODS: In a retrospective study we compared the late outcomes of @entity1 who had undergone operations known to generate @entity338 , namely, transventricular repair of @entity215 and pulmonary commissurotomy for isolated @entity849 . RESULTS: In our institution, between 1964 and 1984, a total of 44 @entity1 were found to have had an isolated pulmonary commissurotomy and 189 survived a transventricular repair of @entity215 . Of these @entity1 , 134 had patching of the right ventricle and 55 direct closure of a right ventriculotomy. Follow-up was 94% complete after a mean of 22 +/- 7 years. On echocardiography, @entity1 with isolated commissurotomy had similar degrees of moderate and severe @entity338 as @entity215 @entity1 who had a right ventricular patch (p > 0.2). However, freedom from adverse events related to @entity1001 was far better (log rank p < 0.001) in @entity1 with isolated commisurotomy. CONCLUSIONS: @entity338 is not the only determinant of late symptomatic @entity1001 after repair of @entity215 . @entity338 seems much more deleterious in @entity1 who have had right ventricular outflow tract patching. Long-term @entity338 alone is responsible for a slight degree of @entity1001 , but symptoms may develop much later if the contractility of the pulmonary infundibulum is preserved. The pulmonary infundibulum may be essential for right ventricular ejection, and for maintaining @entity338 .

Does right ventricular outflow tract damage play a role in the genesis of late XXXX after @entity215 repair?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity215 :: ('MESH:D013771', 'Disease') :: ['tetralogy of Fallot'] @entity338 :: ('MESH:D011665', 'Disease') :: ['pulmonary insufficiency', 'pulmonary valve competence', 'Pulmonary insufficiency'] @entity849 :: ('MESH:D011666', 'Disease') :: ['pulmonary stenosis'] @entity1001 :: ('MESH:C566255', 'Disease') :: ['right ventricular dilatation']
@entity1001 :: (MESH:C566255,Disease) :: ['right ventricular dilatation']
