OBJECTIVE: To determine the molecular epidemiology of @entity378 isolated from @entity1 cared for at eight hospitals scattered throughout New York City. MATERIALS AND METHODS: Cases of @entity378 occurring in 1996 and 1997 at collaborating hospitals were identified, and demographic data were extracted from @entity1 charts. All available isolates were analyzed by IS6110 for genetic relatedness. The molecular fingerprints were compared both to each other and to the larger repository of strains from New York City developed and maintained at the Public Health Research Institute. RESULTS: One hundred and eighty cases were fully characterized. Compared with New York City cases, study @entity1 were more likely to be Asian and less likely to be @entity7864 . Overall, 97 (54%) of the cases were clustered with respect to other study strains or with respect to the other New York City isolates. Clustered strains were significantly more likely to be from @entity7864 or @entity1 born in the United States. The largest cluster (n = 17) was the "W" strain previously associated with an outbreak of @entity6371 in New York City. In the current study, the majority of W strain isolates were fully drug-susceptible. CONCLUSIONS: High rates of genetically related @entity378 continue to occur among @entity1 in New York City, in spite of improved control of nosocomial outbreaks and dramatic decreases in the overall case rates. The use of molecular techniques to suggest patterns of transmission has become essential in developing and assessing routine @entity378 control strategies.

Molecular epidemiology of XXXX among eight hospitals in New York City, 1996-1997.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculosis'] @entity7864 :: ('MESH:D055008', 'Disease') :: ['non-Hispanic blacks'] @entity6371 :: ('MESH:D018088', 'Disease') :: ['multidrug-resistant tuberculosis']
@entity378 :: (MESH:D014376,Disease) :: ['tuberculosis']
