The goal of this study was to investigate the expression profiles of nuclear factor-kappa B (NF-kB) and @entity470 ( @entity470 ) in @entity418 and to determine their association with @entity5 prognosis. This study included 40 @entity418 @entity1 [22 @entity1 and 18 @entity1 ; average age = 62.7    3.9 years; @entity5 -node-metastasis (TNM) staging: 12 @entity1 with stage I, 13 @entity1 with stage II, and 15 @entity1 with @entity5 ]. Tumor tissues and @entity5 -adjacent tissue specimens were collected during radical resections at our hospital. Immunohistochemical staining was used to examine these tissues for NF-kB and @entity470 expression. Follow-up of all @entity1 included gathering information such as the 3-year survival rate. We found that NF-kB and @entity470 expression was significantly higher in @entity5 tissues compared to @entity5 -adjacent normal tissues. Expression was not related to gender or age, but was positively associated with the degree of @entity5 infiltration. NF-kB and @entity470 expression levels gradually increased with higher TNM stage, but this difference was not significant. Follow-up results showed that @entity1 with higher NF-kB and @entity470 levels had a lower survival rate and unfavorable prognosis. In conclusion, we found that NF-kB and @entity470 expression was significantly elevated during the occurrence and development of @entity418 , and expression of these factors appears to be correlated with @entity5 progression. Higher expression of both genes is associated with an unfavorable prognosis.

Expression and prognostic influence of NF-kB and XXXX in @entity418 .

@entity470 :: ('1956', 'Gene') :: ['EGFR', 'epidermal growth factor receptor'] @entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'stage III disease', 'cancer'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal cancer', 'esophageal carcinoma']
@entity470 :: (1956,Gene) :: ['EGFR']
