Angiogenesis is important in the pathogenesis of @entity5 and correlates with clinical outcome in certain @entity5 . Recent advances in staining techniques have raised doubts about the prognostic value of @entity1350 in muscle-invasive @entity150 , for which relatively few predictors for survival exist. Twenty-one radical cystectomy specimens from @entity1 with stage pT2-3NOMO transitional cell @entity5 were examined by staining with @entity1710 and @entity1711 (H_E). Factor VIII-related antigen (FVIII RAG) which is specific for vascular endothelium, and MOVAT which highlights large vessels. Angiogenesis, estimated by microvessel density, and presence of @entity1350 were then correlated with survival in the follow-up period which ranged from 3 to 141 months. Six of 21 @entity1 survived disease-free with follow-up ranging from 47 to 141 months. Twelve @entity1 had lower microvessel density than 178/mm2 and five of these survived, whereas only one of nine @entity1 having higher microvessel density survived. Twelve of 21 @entity1 had @entity1350 and three survived whereas three of nine @entity1 without @entity1350 survived. There was no correlation found between @entity1350 and survival in this study. Analysis by Kaplan-Meir survival curves demonstrated trends which were not statistically significant between high and low angiogenesis groups. The preliminary data suggest that further assessment of the prognostic role of angiogenesis and @entity1350 in muscle-invasive @entity150 is indicated.

Prognostic value of angiogenesis and @entity1350 in muscle-invasive XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors', 'malignancies'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['Eosin'] @entity1350 :: ('MESH:D019043', 'Disease') :: ['vascular invasion'] @entity150 :: ('MESH:D001749', 'Disease') :: ['bladder cancer'] @entity1710 :: ('MESH:D006416', 'Chemical') :: ['Hematoxylin']
@entity150 :: (MESH:D001749,Disease) :: ['bladder cancer']
