Skin and bone share a similar organic constituent (type I collagen) which decreases with time after menopause due to hypoestrogenism. The interdependence of skin and @entity604 has been reported. This study was conducted to assess the predictive value of an ultrasonographic measurement of skin thickness in the diagnosis of @entity2331 ( @entity1555 below -1.5 SD.) in perimenopausal and early postmenopausal @entity1 . All @entity1 had skin thickness measured by the same radiologist and had a dual-energy X-ray absorptiometry (DEXA) scan of the lumbar spine and the femoral neck. Of the 77 @entity1 studied, the mean age was 50.9 +/- 3.0 years. Thirty @entity1 were in perimenopause and 47 in early postmenopause. Mean skin thickness was 2.1 +/- 0.4 mm. @entity1 with a skin thickness of < or = 1.7 mm carried a higher risk for developing @entity2331 at the lumbar spine (odds ratio 8.41, 95% confidence interval 2.19-32.35) and the femoral neck (odds ratio 3.88, 95% CI 1.14-13.17). @entity1 with a skin thickness of > or = 2.4 mm had a lower probability of @entity2331 at the lumbar spines (odds ratio 0.17, 95% CI 0.035-0.845) and the femoral neck (odds ratio 0.22, 95% CI 0.055-0.899). In conclusion, a low skin thickness measurement by ultrasonography may be used as an indicator for @entity2331 in perimenopausal and early postmenopausal @entity1 .

The predictive value of skin thickness in the diagnosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'Women'] @entity1555 :: ('MESH:D020388', 'Disease') :: ['BMD'] @entity604 :: ('MESH:D016301', 'Disease') :: ['bone atrophy'] @entity2331 :: ('MESH:D001851', 'Disease') :: ['osteopenia']
@entity2331 :: (MESH:D001851,Disease) :: ['osteopenia']
