BACKGROUND AND OBJECTIVES: A single injection lumbar @entity616 for acute @entity158 management after hip surgery is usually limited to the immediate postoperative period. We conducted a randomized controlled trial to determine the effect of a continuous lumbar @entity616 on perioperative opioid requirements and @entity158 intensity. METHODS: Adult @entity1 undergoing elective hip arthroplasty under general anesthesia were randomized to continuous lumbar @entity616 combined with @entity1 -controlled analgesia ( @entity4901 ) or @entity4901 only for @entity282 . @entity1 allocated to the lumbar @entity616 had the catheter placed before surgery. @entity1 were followed for 36 hours. Perioperative opioid requirement was the primary outcome; secondary outcomes included assessment of @entity158 intensity, @entity1 and surgeon satisfaction with the analgesic technique, and occurrence of @entity390 and @entity391 . RESULTS: Seventeen @entity1 were randomized to each treatment group. Compared with @entity1 in the @entity4901 group, @entity1 in the continuous lumbar @entity616 group required less @entity1286 (12 mg) (95% CI, -12.9 to -3.9), had on average less @entity158 (-2.1 units on a 0 to 10 scale) (95% CI, -3.8 to -1.1), were more satisfied with their analgesic technique, and experienced less @entity390 and @entity391 . One @entity1 in the continuous lumbar @entity616 developed a delayed paresis and 1 @entity1 in the @entity4901 group developed @entity1576 . CONCLUSIONS: Continuous lumbar @entity616 combined with @entity4901 is superior to @entity4901 alone for @entity282 management following hip replacement. It reduces opioid requirements, opioid related side effects, and enhances @entity1 satisfaction. However, additional research is required to determine its safety in light of the @entity16 observed.

Continuous lumbar XXXX provides improved analgesia with fewer side effects compared with systemic opioids after hip arthroplasty: a randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic injury'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory depression'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity4901 :: ('CHEBI:36751', 'Chemical') :: ['PCA'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity616 :: ('MESH:D006327', 'Disease') :: ['plexus block']
@entity616 :: (MESH:D006327,Disease) :: ['plexus block']
