OBJECTIVE: To analyze all @entity1 with @entity11533 ( @entity11533 ) and @entity5 described in the literature and to discuss their relation to each other. METHOD: Demographic, clinical, and laboratory characteristics of one index @entity1 with @entity11533 seen in our institution who subsequently developed a @entity5 were compared with all other cases of @entity11533 and @entity5 identified by a PubMed literature research. Furthermore, characteristics of @entity11533 @entity1 with @entity5 were compared to those without @entity5 . RESULTS: We found 46 articles in English, French, Japanese, Korean, and Spanish language reporting 47 cases in addition to our own case. In 36 @entity1 , the diagnosis of @entity11533 could be confirmed by retrospectively applying classification criteria according to Yamaguchi, Fautrel, and Crispin. The median time between diagnosis of @entity11533 and subsequent detection of a @entity5 was 9 months, 50% had a @entity1503 and 50% a solid @entity5 . In 33%, the symptoms of @entity11533 resolved after successful therapy of the @entity5 . Red flags for paraneoplastic @entity11533 were onset of symptoms at higher age, atypical features of @entity1910 , highly elevated @entity880 dehydrogenase, atypical cells in the differential blood count, and high concentrations of the soluble interleukin-2 receptor. CONCLUSION: A disease resembling @entity11533 can precede the clinical appearance of a @entity1583 or a solid @entity5 . Thorough diagnostic work-up of @entity11533 to rule out @entity5 and awareness to conspicuous signs for @entity5 -associated @entity11533 are therefore essential in the clinical work-up of such @entity1 .

Adult onset Still's disease associated with XXXX -Cause or coincidence?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity11533 :: ('MESH:D016706', 'Disease') :: ["adult onset Still's disease", 'AOSD'] @entity1910 :: ('MESH:D005076', 'Disease') :: ['rash'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignant disease', 'neoplastic disease', 'malignancy'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['hematological disorder'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity1583 :: ('MESH:D019337', 'Disease') :: ['hematologic malignancy']
@entity5 :: (MESH:D009369,Disease) :: ['malignancy']
