BACKGROUND: Emerging yet separate literatures have highlighted @entity73 (i.e., mild @entity2055 ) and @entity73 in @entity1 with essential @entity400 (ET). However, the relationship between the two has not been studied. The goal of these analyses was to study the relationship between @entity73 and @entity73 in ET. One-hundred-twenty ET cases were enrolled in an epidemiological study at Columbia University Medical Center. A Telephone Interview for Cognitive Status (TICS, range   =   0-41 [no deficits]) was administered and a videotaped assessment of tandem gait was performed, during which the number of missteps during 10-steps was counted. RESULTS: The mean TICS score was 35.7 (range 25-39), and mean number of tandem mis-steps was 2.9 (range 0-10). The number of tandem mis-steps was correlated with the TICS score (Spearman's r   =   -0.245, p   =   0.011, i.e., individuals who had more tandem gait difficulty also had more @entity73 ). In a multivariate analysis, tandem mis-steps were associated with TICS score (p   =   0.04) independent of age and other factors. CONCLUSIONS: More @entity73 was associated with more tandem gait difficulty in ET. Ambulation often requires the concurrent use of both cognitive and motor neural systems; hence it is possible that the cognitive and gait problems in ET reflect an underlying @entity72 affecting both @entity73 .

Tandem gait performance in essential XXXX @entity1 correlates with cognitive function.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive difficulty', 'cognitive problems', 'cognitive and motor circuits', 'gait/balance impairments'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity72 :: ('MESH:D002659', 'Disease') :: ['pervasive disorder'] @entity2055 :: ('MESH:D001259', 'Disease') :: ['ataxia']
@entity400 :: (MESH:D014202,Disease) :: ['tremor']
