OBJECTIVE: @entity740 ( @entity740 ) might be a potential independent risk factor for increased carotid @entity121 ( @entity121 ). Our aim is to determine whether mild to moderate @entity8 is associated with increased carotid @entity121 . METHODS: We employed 3629 subjects free from clinical @entity65 at the baseline visit of the Asymptomatic @entity854 in Community Study. Kidney function was evaluated in terms of estimated glomerular filtration rate (eGFR) calculated by the @entity740 Epidemiology Collaboration China equation. The mean of the maximal internal and common carotid @entity121 was measured by means of high-resolution B-mode ultrasound. Univariable linear regressions and multivariate logistic regressions were used to evaluate the independent association between kidney function and carotid @entity121 . RESULTS: In the unadjusted linear analysis, carotid @entity121 showed a significant negative correlation with eGFR in both male (r   =   -.346, P   <   .001) and female (r   =   -.253, P   <   .001) subjects. After adjustment for age, traditional vascular risk factors (smoking, @entity551 , diastolic blood pressure, @entity1674 , high-density lipoprotein @entity165 , low-density lipoprotein @entity165 , total @entity165 , and antihypertensive drug use), and nontraditional risk factors (C-reactive protein and @entity1255 ), the association remained significant. The odds ratio for increased @entity121 was 1.299 (95% confidence interval [CI], 1.062-1.588) in the group with an eGFR of 60-89   mL/minute/1.73   m(2) and 1.789 (95% CI, 1.203-2.660) in the group with an eGFR of 30-59   mL/minute/1.73   m(2). CONCLUSIONS: Increased @entity121 is associated with early-stage @entity740 . This association is independent of traditional and nontraditional cardiovascular risk factors. Early detection of @entity8 is important to improve risk stratification of @entity731 .

Correlation between Carotid Intima-Media Thickness and Early-Stage XXXX : Results from Asymptomatic @entity854 in Community Study.

@entity8 :: ('MESH:D007674', 'Disease') :: ['kidney dysfunction'] @entity1255 :: ('MESH:D006710', 'Chemical') :: ['homocysteine'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity740 :: ('MESH:D051436', 'Disease') :: ['Chronic kidney disease', 'CKD', 'Chronic Kidney Disease'] @entity854 :: ('MESH:D018376', 'Disease') :: ['Polyvascular Abnormalities'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic disease'] @entity551 :: ('MESH:D007022', 'Disease') :: ['diabetes, systolic blood pressure'] @entity121 :: ('MESH:D009135', 'Disease') :: ['IMT', 'intima-media thickness'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular diseases'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity740 :: (MESH:D051436,Disease) :: ['Chronic Kidney Disease']
