BACKGROUND: The introduction of @entity16 units and of thrombolysis with the intravenous (IV) administration of recombinant tissue-type plasminogen activator (tPA) have markedly improved the treatment of @entity64 . Five randomized trials of catheter-based interventional treatment of @entity64 with special stents were published in 2015. METHODS: Recently published randomized trials of mechanical thrombectomy are selectively reviewed. RESULTS: These trials documented the clinical efficacy of mechanical thrombectomy (MT) in the treatment of occlusion of a major cerebral artery in the distribution of the internal carotid artery (evidence level 1a, recommendation grade A). Roughly 4-10% of all @entity64 @entity1 could benefit from such an intervention. In the trials, 85% of the @entity1 were first treated with IV-tPA. A recanalization of the occluded vessel was achieved by MT in 59-88% of @entity1 . The percentage of @entity1 with no deficit or only a mild deficit was 33-71% among those who received the intervention, compared to 19-40% in the control groups. The trial data indicate that MT is effective for elderly @entity1 as well (age over 80). Thrombectomy did not increase the rate of secondary, symptomatic @entity932 . CONCLUSION: MT can only be used to treat the occlusion of major cerebral arteries. In appropriate @entity1 , it expands the spectrum of treatment options for @entity64 . Long-term data are not yet available.

Mechanical Thrombectomy in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological stroke'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity932 :: ('MESH:D020300', 'Disease') :: ['intracranial hemorrhage']
@entity64 :: (MESH:D020521,Disease) :: ['Stroke']
