OBJECTIVES: Aortic valve bypass (AVB) (apico-aortic conduit) remains an effective surgical alternative for @entity1 in whom surgical aortic valve replacement or transcatheter aortic valve implantation is not feasible. However, specific complications include @entity715 formation, possibly caused by stagnation arising from flow competition between the antegrade and retrograde flow, but this has not been fully investigated. The aim of this study was to analyse flow characteristics after AVB and to elucidate mechanisms of intra-aortic @entity715 using @entity5173 ( @entity5173 ). METHODS: Flow simulation was performed on data obtained from a 73-year-old postoperative AVB @entity1 . Three-dimensional cine phase-contrast magnetic resonance imaging at 3 Tesla was used to acquire flow data and to set up the simulation. The vascular geometry was reconstructed using computed tomography angiograms. Flow simulations were implemented at various ratios of the flow rate between the ascending aorta and the graft. Results were visualized by streamline and particle tracing. RESULTS: @entity5173 demonstrated stagnation in the ascending aorta-arch when retrograde flow was dominant, indicating that the risk of @entity715 formation exists in the ascending arch in cases with severe @entity472 and/or poor left ventricular function. Meanwhile, stagnation was observed in the proximal descending aorta when the antegrade and retrograde flow were equivalent, suggesting that the descending aorta is critical when @entity472 is not severe. CONCLUSIONS: Flow stagnation in the aorta which may cause @entity715 was observed when retrograde flow was dominant and antegrade/retrograde flows were equivalent. Our results suggest that anticoagulants might be recommended even in @entity1 who receive biological valves.

Blood flow competition after aortic valve bypass: an evaluation using XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus'] @entity472 :: ('MESH:D001024', 'Disease') :: ['aortic stenosis'] @entity5173 :: ('MESH:D065634', 'Disease') :: ['CFD', 'computational fluid dynamics']
@entity5173 :: (MESH:D065634,Disease) :: ['computational fluid dynamics']
