The global burden of @entity157 ( @entity157 ; primary @entity96 ) is increasing. @entity157 is often unaccompanied by clear symptomatology, causing @entity1 to be unaware of their disease. Moreover, effective treatment for those with @entity1442 is lacking. As such, effective surveillance and early detection of @entity157 are essential. However, current screening and surveillance guidelines are not being fully implemented. Some at-risk populations fall outside of the guidelines, and @entity1 who are screened are often not diagnosed at an early enough stage for treatment to be effective. From March 17 to 19, 2015, the @entity1956 Foundation sponsored a workshop to identify gaps and limitations in current approaches to the detection and treatment of @entity157 and to define research priorities and opportunities for advocacy. In this Commentary, we summarize areas for further research and action that were discussed throughout the workshop to improve the recognition of @entity409 generally, improve the recognition of @entity96 risk, and improve the recognition that screening for @entity157 makes a life-saving difference. @entity1 agreed that primary prevention of @entity157 relies on prevention and treatment of @entity99 and other underlying etiologies. Earlier diagnosis (secondary prevention) needs to be substantially improved. Areas for attention include increasing practitioner awareness, better definition of at-risk populations, and improved performance of screening approaches (ultrasound, biomarkers for detection, risk stratification, targeted therapies). The heterogeneous nature of @entity157 makes it unlikely that a single therapeutic agent will be universally effective. Medical management will benefit from the development of new, targeted treatment approaches.

XXXX : Gaps and Opportunities to Improve Care.

@entity1 :: ('9606', 'Species') :: ['patients', 'Participants'] @entity1956 :: ('MESH:D006509', 'Disease') :: ['Hepatitis B'] @entity96 :: ('MESH:D008113', 'Disease') :: ['liver cancer'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver disease'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['advanced disease'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma'] @entity99 :: ('MESH:D056486', 'Disease') :: ['viral hepatitis']
@entity96 :: (MESH:D008113,Disease) :: ['Hepatitis-Associated Liver Cancer']
