OBJECTIVE: Our objective was to perform an updated systematic review to compare the efficacy and short- and long-term mortality of surgical myectomy (SM) and @entity285 septal ablation (ASA) by including most recent and largest cohort studies published in last few years. BACKGROUND: SM and ASA are the two invasive strategies used to relieve @entity3585 ( @entity3585 ) in @entity1 with drug refractory symptomatic @entity1121 ( @entity1121 ). In the absence of a randomized trial, we tried to compare the pros and cons of the two procedures using a systematic review and meta-analysis. METHOD: A comprehensive search of three major databases was performed. We included original research studies comparing data on ASA and SM. Of 1,143 citations, 10 studies were included in the analysis. RESULTS: A total of 805 @entity1 underwent ASA and 1,019 underwent SM. @entity1 undergoing SM were younger ( @entity601 6.3, P   =   0.0001) and had higher reduction in the LVOT gradient ( @entity601 -9.56, P   =   0.05). However, there was similar resolution of class III and IV symptoms between the two groups (P   =   0.56). There was no difference in @entity1164 ( @entity1164 ) (P   =   0.93), short-term (P   =   0.36), long-term all cause (P   =   0.27), and long-term cardiac mortality (P   =   0.58). @entity1 undergoing ASA had higher incidence of post procedure device implantation (OR 3.09, P   <   0.00001). CONCLUSION: No significant difference in symptom relief was noted between the two approaches. ASA was as safe a myectomy with regards to @entity1164 , short-term, and long-term mortality.    2015 Wiley Periodicals, Inc.

A meta analysis of current status of @entity285 septal ablation and surgical myectomy for obstructive XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1164 :: ('MESH:D016757', 'Disease') :: ['sudden cardiac death', 'SCD'] @entity3585 :: ('MESH:D014694', 'Disease') :: ['left ventricular outflow tract obstruction', 'LVOTO'] @entity601 :: ('MESH:D009436', 'Disease') :: ['MD'] @entity285 :: ('D000431', 'Chemical') :: ['alcohol'] @entity1121 :: ('MESH:D002312', 'Disease') :: ['HCM', 'hypertrophic cardiomyopathy']
@entity1121 :: (MESH:D002312,Disease) :: ['hypertrophic cardiomyopathy']
