BACKGROUND: Efficacy of topical @entity230 in @entity1665 areata is still discussed. OBJECTIVE: The purpose of this study was to evaluate the efficacy of @entity6914 0.05% ointment under occlusion in 28 @entity1 with @entity1665 @entity1663 ( @entity1663 ) or @entity1663 / @entity1665 universalis. METHODS: A total of 28 @entity1 were instructed to apply 2.5 g of @entity6914 to the right side of the scalp every night under occlusion with a plastic film. Treatment was performed 6 days a week for 6 months. When regrowth of terminal hair occurred, treatment was extended over the entire scalp. All @entity1 were followed up for another 6 months. RESULTS: Of the 28 @entity1 included in the study, 8 were treated successfully (28.5%). Regrowth of terminal hair began on the treated side 6 to 14 weeks after the start of treatment. Of these 8 @entity1 , 3 had a relapse and were not able to maintain hair regrowth. CONCLUSION: Our study shows that @entity6914 0.05% under occlusion is effective in inducing hair regrowth in @entity1 with @entity1663 or @entity1663 / @entity1665 universalis. Occurrence of hair regrowth only on the treated half of the scalp clearly shows that efficacy of treatment is a result of a local and not systemic effect of the drug. Although only 17.8% of @entity1 had long-term benefit by treatment, our results were obtained in a population of @entity1 with severe and refractory forms of the disease.

XXXX 0.05% under occlusion in the treatment of @entity1665 /universalis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1665 :: ('MESH:D000505', 'Disease') :: ['alopecia'] @entity6914 :: ('MESH:D002990', 'Chemical') :: ['clobetasol propionate'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity1663 :: ('MESH:D000506', 'Disease') :: ['areata totalis', 'AT']
@entity6914 :: (MESH:D002990,Chemical) :: ['Clobetasol propionate']
