BACKGROUND: Live commensal intestinal bacteria are present in the peripheral blood where they can induce @entity32 . OBJECTIVE: To evaluate the intestinal bacteria composition and translocation of bacteria in @entity8787 . METHODS: Both blood and tissue biopsy samples were collected from adult @entity1 with active/inactive @entity30 ( @entity30 ), active/inactive @entity31 ( @entity31 ) and healthy individuals. Most of the @entity1 were newly diagnosed and none of them received antibiotics. Using a reverse transcription-quantitative real-time PCR (RT-qPCR) method, we determined the composition of microbiota. @entity6820 / @entity6820 genotyping was also studied. RESULTS: Total bacterial DNA concentration was increased in tissue and blood samples of @entity8787 @entity1 compared to healthy controls. Furthermore, the active @entity8787 cases had higher total bacterial DNA concentration levels compared to the inactive cases. Three species characterized @entity6636 in @entity8787 , namely an increase of Bacteroides spp in active and inactive @entity8787 samples, and a decrease in Clostridium leptum group (IV), and Faecalibacterium prausnitzi in both active and inactive @entity8787 @entity1 . No significant association between bacterial translocation and @entity6820 / @entity6820 mutations was found. CONCLUSIONS: The composition of the microbiota in @entity8787 @entity1 differs from that of healthy controls. The high rate of bacterial DNA in the blood samples indicates translocation in @entity29 .

Intestinal Bacteria Composition and Translocation of Bacteria in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity6636 :: ('MESH:D064806', 'Disease') :: ['dysbiosis'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease'] @entity6820 :: ('64127', 'Gene') :: ['CARD15', 'NOD2'] @entity8787 :: ('MESH:C535541', 'Disease') :: ['IBD'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"]
@entity29 :: (MESH:D015212,Disease) :: ['Inflammatory Bowel Disease']
