PURPOSE: Local control for @entity2828 ( @entity2828 ) has improved in modern studies. However, it is unclear if these gains have also been achieved for @entity5 . The purpose of this study is to evaluate local control and survival in pelvis @entity2828 @entity1 treated in the modern @entity7971 . METHODS: All pelvis @entity2828 @entity1 diagnosed from 1990 to 2012 and seen at Mayo Clinic were identified. Factors relevant to survival and local control were analyzed. RESULTS: The cohort consisted of 48 @entity1 . Fifty-two percent had metastatic disease at diagnosis. The 5-year overall survival and event-free survival was 73% and 65%, respectively, for @entity66 . The 5-year cumulative incidence of local recurrence was 19%, with a 26% incidence for radiation, 13% for surgery, and 0% for surgery + radiation (P = 0.54). All local failures occurred in-field. Sacral involvement by @entity5 trended toward a higher incidence of local recurrence (hazard ratio 3.06, P = 0.09). @entity1 treated with definitive radiation doses >= 5,600 cGy had a lower incidence of local recurrence (17% vs. 28%, P = 0.61). CONCLUSIONS: Our study demonstrates excellent survival for localized @entity5 in the modern @entity7971 . Anatomical localization within the pelvis likely correlates with outcomes. Local control remains problematic, especially for @entity1 treated with definitive radiation. Though statistically not significant, surgery + radiation and definitive radiation dose >= 5,600 cGy were associated with the lowest incidence of local failure, suggesting treatment intensification may improve local control for pelvis @entity2828 .

Pelvis XXXX : Local control and survival in the modern @entity7971 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2828 :: ('MESH:D012512', 'Disease') :: ['ES', 'Ewing sarcoma'] @entity7971 :: ('26284', 'Gene') :: ['era'] @entity66 :: ('MESH:D004194', 'Disease') :: ['localized disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'pelvis tumors', 'tumors']
@entity2828 :: (MESH:D012512,Disease) :: ['Ewing sarcoma']
