Antineutrophil cytoplasmic antibody-associated @entity13571 (AASV) frequently leads to @entity454 ( @entity454 ). Potentially fatal disease activity can continue after the onset of @entity454 in both dialysis and transplant @entity1 , despite the immunosuppressive effects of @entity5507 and rejection prophylaxis, leading to concerns that such @entity1 have greater morbidity and mortality. To assess the outcome of AASV @entity1 receiving renal replacement therapy, a retrospective analysis of 59 @entity1 from our unit who received chronic dialysis, renal transplantation, or both, was performed. The survival of AASV @entity1 with @entity454 was comparable to national registry controls, as were both graft and @entity1 survival after renal transplantation. Ther is no evidence that standard immunosuppressive protocols should be altered for AASV @entity1 receiving renal transplants. The rate of relapse of @entity1333 for @entity1 on chronic dialysis and after transplantation was 0.09 and 0.02 per @entity1 per year, respectively. These rates are lower than those of other series and support the contention that continued immunosuppression after @entity454 , as practiced in our unit, is warranted. Relapses usually responded to @entity786 and high-dose @entity617 treatment. Significantly, vasculitic flare-ups in dialysis @entity1 were sometimes initially misdiagnosed as dialysis complications, leading to fatal delays in effective treatment. Follow-up by physicians experienced in the diagnosis and treatment of @entity1333 activity should continue in these @entity1 .

Outcome of renal replacement therapy in antineutrophil cytoplasmic antibody-associated XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity13571 :: ('MESH:D056647', 'Disease') :: ['systemic vasculitis'] @entity1333 :: ('MESH:D014657', 'Disease') :: ['vasculitis'] @entity5507 :: ('MESH:D014511', 'Disease') :: ['uremia'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide'] @entity617 :: ('MESH:D011239', 'Chemical') :: ['prednisolone'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal disease', 'ESRD']
@entity13571 :: (MESH:D056647,Disease) :: ['systemic vasculitis']
