A selection experiment utilizing @entity5872 was initiated to study the genetic relationship of growth and reproduction traits. In this study, lines were selected for increased ( @entity4306 line) and decreased (LP line) total plasma @entity3151 at the beginning of lay. The @entity4306 and LP lines were derived from a randombred control population (R1 line) that was maintained with the selected lines to remove environmental variation over generations. During the course of selection, it was observed that blood from @entity4306 line females was more viscous than that of the LP and R1 females. In later generations of selection, mortality of females during a 120-d egg production period was higher in the @entity4306 line than in the LP and R1 lines. The purpose of this experiment was to identify possible factors contributing to the increased mortality in the @entity4306 line. Fearfulness, as measured by tonic immobility, was greater in the @entity4306 and LP lines than in the R1 line. Indirect blood pressure measurements were made near the beginning and near the end of the 120-d egg production period. No significant line differences were observed in either measurement. Weight of the heart at the end of the laying period was higher in the @entity4306 and LP lines than in the R1 line. Histological study of the hearts of the @entity4306 and R1 lines indicated significant @entity4306 line in collagen content of the coronary arteries and in @entity296 . The data suggest that the increased mortality of females of the @entity4306 line relative to the R1 line during the laying period may be related to increased fearfulness and changes in the coronary structure leading to @entity299 .

The effect of divergent selection for total plasma XXXX in @entity5872 on fearfulness and selected blood and heart parameters.

@entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial fibrosis'] @entity4306 :: ('MESH:C537262', 'Disease') :: ['increases in the HP', 'HP'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart abnormalities'] @entity5872 :: ('93934', 'Species') :: ['Japanese quail'] @entity3151 :: ('MESH:D010758', 'Chemical') :: ['phosphorus']
@entity3151 :: (MESH:D010758,Chemical) :: ['phosphorus']
