BACKGROUND: Whole body cardiovascular MR (WB CVMR) combines whole body angiography and cardiac MR assessment. It is accepted that there is a high disease burden in @entity1 with @entity6 , however the quantification of the whole body @entity1856 burden in both arterial and @entity299 has not been previously reported. In this study we compare the quantified @entity1856 burden in those individuals with and without @entity6 by clinical @entity65 ( @entity65 ) status. METHODS: 158 @entity1 underwent WB CVMR, and were categorised into one of four groups: (1) @entity6 ( @entity6 ) with @entity65 ; (2) @entity6 without @entity65 ; (3) @entity65 without @entity6 ; (4) healthy controls. The arterial tree was subdivided into 31 segments and each scored according to the degree of @entity850 . From this a standardised @entity1856 score (SAS) was calculated. Cardiac MR and late @entity2287 enhancement images of the left ventricle were obtained for assessment of mass, volume and myocardial scar assessment. RESULTS: 148 @entity1 completed the study protocol--61% male, with mean age of 64    8.2 years. SAS was highest in those with @entity65 without @entity6 [10.1 (0-39.5)], followed by those with @entity6 and @entity65 [4 (0-41.1)], then those with @entity6 only [3.23 (0-19.4)] with healthy controls having the lowest @entity1856 score [2.4 (0-19.4)]. Both groups with a prior history of @entity65 had a higher SAS and left ventricular mass than those without (p < 0.001 for both). However after accounting for known cardiovascular risk factors, only the SAS in the group with @entity65 without @entity6 remained significantly elevated. 6% of the @entity6 group had evidence of silent @entity583 , with this subcohort having a higher SAS than the remainder of the @entity6 group [7.7 (4-19) vs. 2.8 (0-17), p = 0.024]. CONCLUSIONS: Global @entity1856 burden was significantly higher in those with known @entity65 and without @entity6 but not in those with @entity6 and @entity65 suggesting that @entity65 may occur at a lower @entity1856 burden in @entity6 .

Cohort comparison study of XXXX and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes', 'T2DM', 'type 2 diabetes mellitus'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac disease'] @entity1856 :: ('MESH:D058226', 'Disease') :: ['atheroma'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarct'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease', 'cardiovascular events']
@entity299 :: (MESH:D006331,Disease) :: ['cardiac disease']
