BACKGROUND: @entity24732 ( @entity24732 ) allows for the study of @entity296 (  ), a marker of early and @entity67 . @entity299 may be present in @entity1 with @entity2012 ; however, @entity24732 has never been used to evaluate these @entity1 . OBJECTIVE: To evaluate left @entity1002 in @entity1 with active @entity2012 with normal LV systolic function. DESIGN: Cross-sectional clinical study. METHODS: @entity1 with active @entity2012 with no detectable @entity299 and a control group were matched for age, gender, arterial @entity101 and @entity6 underwent @entity24732 . @entity1002    (GLS), left ventricular mass index (LVMi), left ventricular ejection fraction (LVEF) and @entity121 ( @entity121 ) were obtained via two-dimensional (2D) echocardiography using @entity24732 . RESULTS: Thirty-seven @entity1 with active @entity2012 (mean age 45.6        13.8; 48.6% were males) and 48 controls were included. The mean GLS was not significantly different between the @entity2012 group and the control group (in %, -20.1        3.1 vs. -19.4        2.2, p   =   0.256). Mean LVMi was increased in the @entity2012 group (in g/m(2), 101.6        27.1 vs. 73.2        18.6, p   <   0.01). There was a negative correlation between LVMi and GLS (r   =   -0.39, p   =   0.01). CONCLUSIONS: @entity2012 @entity1 , despite presenting with a higher LVMi when analyzed by 2D echocardiography, did not present with impairment in the strain when compared to a control group; this finding indicates a low chance of evolution to @entity299 and agrees with recent studies that show a lower frequency of @entity299 in these @entity1 .

Two-dimensional speckle tracking echocardiography demonstrates no effect of active XXXX on left ventricular strain.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial strain'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity2012 :: ('MESH:D000172', 'Disease') :: ['acromegaly', 'Acromegaly'] @entity24732 :: ('MESH:C563256', 'Disease') :: ['Speckle tracking echocardiography', 'STE'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac disease', 'Cardiac disease', 'systolic dysfunction', 'heart disease'] @entity67 :: ('MESH:D018754', 'Disease') :: ['subclinical ventricular systolic dysfunction'] @entity121 :: ('MESH:D009135', 'Disease') :: ['relative wall thickness', 'RWT'] @entity1002 :: ('MESH:D018487', 'Disease') :: ['Global LV longitudinal', 'ventricular (LV) global longitudinal strain']
@entity2012 :: (MESH:D000172,Disease) :: ['acromegaly']
