PURPOSE: @entity303 has several different etiologies, and @entity1294 ( @entity1294 ) is considered the second leading cause of @entity303 after @entity195 ( @entity195 ). Various studies used blink reflex in different spectrum of @entity16 as a complementary diagnostic test. We performed blink test in @entity195 , @entity1294 , and mixed @entity303 to investigate different usefulness of blink reflex in differentiating these types of @entity303 . METHODS: Blink reflex was performed for @entity1 with @entity195 (n = 18), @entity1294 (n = 17), mixed @entity303 (n = 19), and normal subjects (n = 20). The absolute latency of R1, @entity16071 (R2c) was determined and then compared with normal values. We used ROC curve to determine the screening cut-off value for R2 and R2c to discriminate @entity303 with vascular component and @entity195 . RESULTS: The mean age    SD of @entity1 was 71.61    8.23, 66.71    11.48, 75.26    8.32, and 66.60    3.91 years in 4 groups of @entity195 , @entity1294 , mixed @entity303 , and normal, respectively. R2 and R2c were recorded in fewer number of subjects with @entity1294 or mixed @entity303 than @entity195 and normal subjects. For mean R2 latency higher than 45 milliseconds, the sensitivity and specificity were 42% and 100%, respectively, and for latency higher than 45 milliseconds, the sensitivity and specificity were 72% and 89%, respectively. CONCLUSIONS: R2 and R2c components of blink reflex could specifically discriminate between Alzheimer and @entity303 with vascular component. The interruption of descending corticoreticular pathways by small @entity1188 could explain it.

Blink Reflex May Help Discriminate XXXX From @entity1294 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity303 :: ('MESH:D003704', 'Disease') :: ['Dementia', 'dementia'] @entity1294 :: ('MESH:D015140', 'Disease') :: ['vascular dementia', 'VaD'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological diseases'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarcts'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', 'Alzheimer disease'] @entity16071 :: ('6241', 'Gene') :: ['R2, and contralateral R2']
@entity195 :: (MESH:D000544,Disease) :: ['Alzheimer Disease']
