BACKGROUND: Two severe cases of @entity5441 with @entity1109 , @entity5406 , @entity1712 and @entity809 are reported. Definition, etiology, pathophysiological mechanisms, types, complications and therapeutic approaches of this relatively rare clinical disorder are discussed on the basis of these two cases. The distinction between @entity1712 and @entity5441 is clearly defined. DIFFERENTIAL DIAGNOSIS: The 2 cases of @entity5441 demonstrate the difficulty to decide whether they represent the idiopathic or the reactive type of @entity5441 . If the assumption is made in favor of the reactive type of @entity5441 the assumed prognosis could eventually be too promising. In case of an assumed idiopathic type of @entity5441 the search for causing factors like allergens could be left out. The decision concerning the type of @entity5441 cases reported was made with high probability. In the case of @entity5441 , @entity1778 was excluded by bone marrow biopsy. CONCLUSION: In order to be able to make a diagnosis it is necessary to search carefully for causing and influencing factors of the @entity5441 such as allergens or medicaments and to eliminate them. The @entity5441 must be put under frequent control in order to avoid complications or to start with therapeutic approaches in time.

[Spectrum of XXXX syndrome based on 2 clinical case reports].

@entity1712 :: ('MESH:D004802', 'Disease') :: ['eosinophilia', 'eosinophilic ileocolitis'] @entity809 :: ('MESH:D010292', 'Disease') :: ['paresthesia'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['cardiopulmonary symptoms'] @entity5441 :: ('MESH:D017681', 'Disease') :: ['hypereosinophilic syndrome', 'hypereosinophilic syndrome of the 2', 'idiopathic hypereosinophilic syndrome'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['eosinophilic leukemia'] @entity5406 :: ('MESH:D004893', 'Disease') :: ['erythema nodosum']
@entity1712 :: (MESH:D004802,Disease) :: ['hypereosinophilia']
