OBJECTIVE: The study aims to evaluate all @entity1 who underwent liver resection for metastatic disease for demographics, characteristics of the @entity5 and metastasis, volume of liver resection specimens per pathology laboratory and to describe trends in surgical treatment. METHODS: Data were prospectively collected using the Dutch nationwide pathology network. All pathology reports containing details on liver resections for metastatic disease between January 2001 and December 2010 were evaluated. RESULTS: A total of 3,916 liver resections were performed in 3,699 @entity1 with a median age of 63 years (range 1-91). The @entity5 was mainly colorectal (n = 3,256; 88.0%). The number of 'high volume liver centers' increased from 2 to 12 in the study period, whereas the number of 'low volume centers' decreased. The number of liver resections increased from 224 to 596 per year (p  <= 0.0001). A significant increase was demonstrated in elderly @entity1 , @entity1 with multiple @entity3 , liver resections for smaller @entity3 and minor liver resections. CONCLUSION: Although the majority of @entity1 were young and had solitary metastasis, indications for liver resection are expanding as indicated by increasing numbers of elderly and @entity1 with multiple liver @entity3 . @entity1 with non-colorectal liver @entity3 were seldom candidates for resection.

Liver Resection for XXXX ; A Population-Based Analysis of Trends.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity3 :: (MESH:D009362,Disease) :: ['Metastatic Disease']
