PURPOSE: To assess whether magnetic resonance (MR) spectroscopic imaging with MR imaging can improve @entity263 localization in postbiopsy @entity548 cases. MATERIALS AND METHODS: Records of 175 @entity1 with @entity263 were retrospectively reviewed; 42 @entity1 (135 @entity548 sites) had spatially correlated biopsy data. @entity1 underwent both phased-array coil-endorectal coil MR imaging and three-dimensional MR spectroscopic imaging within 180 days after transrectal ultrasound (US)-guided biopsy. High-signal-intensity @entity548 on T1-weighted images and corresponding high- or low-signal-intensity areas on T2-weighted images and the metabolic ratio ( @entity1877 + @entity908 )/ @entity1792 were recorded. @entity5 was identified as a low-signal-intensity area at T2-weighted MR imaging or a metabolite ratio greater than 3 standard deviations above normal at MR spectroscopic imaging. MR imaging, spectroscopic, and biopsy findings were compared. RESULTS: Forty-nine @entity1 had postbiopsy @entity548 . On T2-weighted images, a higher (P < .01) percentage of @entity548 sites demonstrated low signal intensity (80% [108 of 135 sites]), which is similar to the signal intensity seen with @entity5 . The addition of MR spectroscopic imaging to MR imaging resulted in a significant increase (P < .01) in the accuracy (52% to 75%) and specificity (26% to 66%) of @entity5 detection. CONCLUSION: The addition of MR spectroscopic imaging to MR imaging significantly improves the ability to determine the presence of @entity263 and spatial extent when postbiopsy changes hinder interpretation with MR imaging alone.

XXXX in the presence of postbiopsy changes on MR images: role of proton MR spectroscopic imaging.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhagic', 'hemorrhage'] @entity1792 :: ('MESH:D019343', 'Chemical') :: ['citrate'] @entity908 :: ('MESH:D003401', 'Chemical') :: ['creatine'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer', 'Cancer'] @entity1877 :: ('MESH:D002794', 'Chemical') :: ['choline']
@entity263 :: (MESH:D011471,Disease) :: ['Localizing prostate cancer']
