OBJECTIVE: Cone margin status has been reported to be the most important predictor of recurrent disease in @entity1 with @entity3146 ( @entity3146 ) undergoing cervical conization. Our purpose was to evaluate the conservative management of selected @entity1 with microinvasive (FIGO stage @entity9216 ) @entity957 who have been treated by cervical conization with positive margins. METHODS: Twenty-seven @entity1 underwent KTP laser conization and vaporization for stage @entity9216 @entity957 followed by careful observation. Involved margins were diagnosed if @entity3146 or more was present at the ectocervical or endocervical margin and 7 @entity1 formed the basis of the present study. Follow-up consisted of cytology, histology, and pelvic examination. Disease recurrence was defined as a histology diagnosis of @entity3146 or more on colposcopically directed biopsy or endocervical curettage. RESULTS: The endocervical margins were involved by @entity189 in situ in seven (26%) @entity1 . No ectocervical margin involvement was detected. No lymph-vascular space involvement (LVSI) and confluent invasion were seen. All seven @entity1 were free of recurrent disease during median follow-up of 4.0 (range 2.3-7.6) years. CONCLUSION: These results suggest that laser conization and vaporization may be a reasonable treatment option in @entity1 with microinvasive (FIGO Stage @entity9216 ) @entity957 despite positive cone margins without invasive disease when LVSI is not demonstrated.

Stage @entity9216 XXXX : conservative management after laser conization with positive margins.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity9216 :: ('3642', 'Gene') :: ['Ia1'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity3146 :: ('MESH:D018290', 'Disease') :: ['cervical intraepithelial neoplasia', 'CIN III', 'CIN']
@entity957 :: (MESH:D002294,Disease) :: ['cervical squamous cell carcinoma']
