BACKGROUND: @entity5746 of the aorta and adjacent arteries is rare, but life-threatening. There is an increasing number of @entity281 caused by antimicrobial drug resistant @entity5746 . This study sought to assess the association between antimicrobial drug resistance and clinical outcomes of @entity1 with @entity5880 . METHODS: Data were collected by retrospective chart review. Between October 1995 and October 2004, 34 @entity1 with @entity5880 were included. @entity204 were defined as hospital deaths and late deaths due to prosthetic graft infection. Analysis was performed using the chi2 test, Fisher's exact test, and Mann-Whitney test. RESULTS: Nineteen @entity1 had a suprarenal and 15 @entity1 had an @entity281 . The most common responsible pathogen was group C @entity5746 (47%). @entity2177 -resistant @entity5746 occurred since March 2001 and the rate increased from 0 per 15 in the years before March 2001 to 5 per 19 in the years after March 2001 (p = 0.005 by Fisher's exact test). Among the 26 @entity1 who had combined medical and surgical therapy, 4 died in the hospital and 4 died of late prosthetic graft infection 3 to 6 months after operation, whereas 4 of the 8 who had medical therapy alone died of @entity1756 during hospitalization. The actuarial survival rates by the Kaplan-Meier method were 64% at 6 months, 61% at 1 year, and 56% at 5 years. The risk factors for @entity204 were old age (78.5 +/- 9.7 years vs 63.5 +/- 11.4 years; p < 0.001) and @entity2177 -resistant @entity5746 (4 of 5 vs 8 of 29; p = 0.042). CONCLUSIONS: There was an increased mortality associated with @entity2177 resistance in infected @entity449 with @entity5746 . With an increasing incidence of @entity2177 resistant @entity5746 , third generation @entity5898 is the antibiotic of @entity5880 .

Antimicrobial drug resistance in salmonella-infected XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5880 :: ('MESH:D000785', 'Disease') :: ['Salmonella-infected aortic aneurysm', 'choice for Salmonella-infected aneurysm'] @entity449 :: ('MESH:D001014', 'Disease') :: ['aortic aneurysms'] @entity2177 :: ('MESH:D002939', 'Chemical') :: ['Ciprofloxacin', 'ciprofloxacin'] @entity5898 :: ('CHEBI:23066', 'Chemical') :: ['cephalosporin'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infrarenal aortic infection', 'infections'] @entity5746 :: ('MESH:D012480', 'Disease') :: ['Salmonella infection', 'Salmonella'] @entity204 :: ('MESH:D003643', 'Disease') :: ['Aneurysm-related deaths', 'aneurysm-related death'] @entity1756 :: ('MESH:D017542', 'Disease') :: ['aneurysm rupture']
@entity449 :: (MESH:D001014,Disease) :: ['aortic aneurysms']
