OBJECTIVE: Contradictory reports have been published on gastric emptying in @entity1 with @entity1575 . The differences have been attributed to differences in the innervation of the stomach or in the behaviour of the gastric wall. The type of test meal used may, however, have its importance. We looked for the role of the test meal in the assessment of gastric emptying in @entity82 . DESIGN: In a prospective study, we included 15 @entity1 with @entity1575 who had no symptoms of @entity4148 , portal hypertensive gastropathy or @entity19789 and 15 controls. In these subjects we estimated the gastric emptying and varied the type of test meals. METHODS: An ultrasonographic method was used for the estimation of gastric emptying. Antral area was monitored in the aorto-mesenteric plane in the fasting condition and at 0, 15, 30, 45, 60 min after a test meal. Each @entity1 was tested twice on 2 consecutive days in randomized order with a liquid meal (220 kJ) and a semisolid meal (1472 kJ). RESULTS: Fasting antral areas (mean +/- SD) had similar size in both groups with both meals. Gastric emptying (expressed by the area under the curve and half-time (T1/2)) of the semisolid meal was not different in @entity82 (2347 +/- 1648) compared to controls (2840 +/- 1983). @entity4053 was also similar in both groups (312.2 +/- 133.6% in @entity82 vs. 397.9 +/- 155.6% in controls). But emptying of the liquid meal was accelerated in the cirrhotic @entity1 with respect to the area under the curve (AUC: 882 +/- 548) and half-time (12 +/- 2 min) vs. controls (AUC: 1863 +/- 1088, P<0.01; T1/2: 18 +/- 7 min, P<0.05). @entity4053 with the liquid meal was decreased (299.4 +/- 76.5% vs. 431.5 +/-154.0%, P<0.01, in controls). CONCLUSION: These data suggest that in @entity1 with @entity1575 free of @entity4148 and without portal hypertensive gastropathy or @entity19789 , gastric emptying of liquid low calorie meals is accelerated. The gastric emptying of a semisolid meal richer in calories is normal. Thus, the physical and chemical properties of a meal are major determinants of gastric emptying and may account for the large divergence of results hitherto published on this topic.

Gastric emptying in XXXX . The effect of the type of meal.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity19789 :: ('MESH:D020252', 'Disease') :: ['antral vascular ectasia', 'vascular antral ectasia'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity4053 :: ('MESH:D007003', 'Disease') :: ['Postprandial antral distension'] @entity4148 :: ('MESH:D001342', 'Disease') :: ['autonomic neuropathy'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['liver cirrhosis']
@entity1575 :: (MESH:D008103,Disease) :: ['liver cirrhosis']
