The complete @entity377 sequence of the mitochondrial (mt) DNA molecule of the liverfluke, @entity8072 (phylum Platyhelminthes, class Trematoda, family Fasciolidae), was determined. It comprises 14462 bp, contains 12 protein-encoding, 2 ribosomal and 22 transfer RNA genes, and is the second complete flatworm (and the first trematode) mitochondrial sequence to be described in detail. All of the genes are transcribed from the same strand. Of the genes typically found in mitochondrial genomes of eumetazoans, only atp8 is absent. The nad4L and nad4 genes overlap by 40 nt. Most intergenic sequences are very short. Two larger non-coding regions are present. The longer one (817 nt) is located between trnG and @entity69621 and consists of 8 identical tandem repeats of 85 nt, rich in G and C, followed by 1 imperfect repeat. The shorter non-coding region (187 nt) exhibits no special features and is separated from the longer region by trnG. The gene arrangement resembles that of some other @entity2439 including the eastern Asian @entity380 species (and cyclophyllidean cestode species) but it is strikingly different from that of the African schistosomes, represented by @entity380 . The genetic code is as inferred previously for flatworms. Transfer RNA genes range in length from 58 to 70 nt, their products producing characteristic 'clover leaf' structures, except for tRNA(S(UNC)) and tRNA(S(AGN)) lacking the DHU arm.

Complete DNA sequence and gene organization of the mitochondrial genome of the liverfluke, XXXX L. (Platyhelminthes; Trematoda).

@entity69621 :: ('800035(Tax:6192)', 'Gene') :: ['cox3'] @entity377 :: ('CHEBI:36976', 'Chemical') :: ['nucleotide'] @entity2439 :: ('MESH:D014201', 'Disease') :: ['trematodes'] @entity380 :: ('6183', 'Species') :: ['Schistosoma mansoni', 'Schistosoma'] @entity8072 :: ('6192', 'Species') :: ['Fasciola hepatica']
@entity8072 :: (6192,Species) :: ['Fasciola hepatica']
