Occurrence of reduced @entity79 among adolescent @entity1 and young @entity1 due to certain specific @entity2589 or @entity2588 ( @entity448 nervosa, excessive sport or ballet, etc.) is well known. However the prevalence of @entity2331 among 16-18 years old @entity1 with the cycle disorders mentioned above--caused by "pure" hypothalamo- @entity11157 --is not yet sufficiently examined. The hormonal (FSH, LH, prolactin, LH/FSH, @entity53 . @entity251 , @entity1420 ) and ion (Ca++,PO4(3-),Na+,K+,Cl-) parameters and the @entity79 ( @entity79 ) of the lumbar spine of 19 @entity1 age 16-18 with @entity2589 or secondary @entity2588 , @entity11157 were investigated, and correlation were searched for among them. In 3 of the case significant @entity79 reduction was found with a value lower than the -2 SD. compared to the age, sex and race matched control values, showing definite @entity170 . The @entity79 of 10 @entity1 was between the -2.SD. and -1 SD.: they had @entity2331 . Only 6 of them had normal @entity79 ranging from the -1 SD. to the +1 SD. Neither the ion or hormonal values, nor the clinical parameters (height, weight age, age at menarche, duration of amenorrheic period) showed correlation with the @entity79 values, except of the body mass index (BMI), which showed a loose positive linear correlation. The measured low @entity79 values have a significance, referring to a possible reduction in the peak @entity79 . @entity1 having low peak @entity79 have an inclination for earlier, and more sever @entity170 and @entity174 in the climacteric decades. These results emphasize the need of effective and early treatment of adolescent bleeding disorders from the point of view of prevention of @entity170 as well.

[Lower bone density ( @entity2331 ) in adolescent @entity1 with @entity2589 and secondary XXXX ].

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'girls'] @entity251 :: ('MESH:D013739', 'Chemical') :: ['testosterone'] @entity11157 :: ('MESH:D016649', 'Disease') :: ['pituitary-ovarian insufficiency', 'due to hypothalamo-pituitary-ovarian axis insufficiency'] @entity1420 :: ('MESH:D011374', 'Chemical') :: ['progesterone'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures'] @entity170 :: ('MESH:D010024', 'Disease') :: ['osteoporosis'] @entity448 :: ('MESH:D000855', 'Disease') :: ['anorexia'] @entity53 :: ('MESH:D004958', 'Chemical') :: ['estradiol'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity2331 :: ('MESH:D001851', 'Disease') :: ['osteopenia'] @entity2589 :: ('MESH:D009839', 'Disease') :: ['oligomenorrhea'] @entity2588 :: ('MESH:D000568', 'Disease') :: ['amenorrhea']
@entity2588 :: (MESH:D000568,Disease) :: ['amenorrhea']
