UNASSIGNED: Plants use cell-surface-resident receptor-like kinases (RLKs) to sense diverse extrinsic and intrinsic cues and elicit distinct biological responses. In @entity958 , ERECTA family RLKs recognize EPIDERMAL PATTERNING FACTORS (EPFs) to specify stomatal patterning. However, little is known about the molecular link between ERECTA activation and intracellular signaling. We report here that  the SOMATIC EMBRYOGENESIS RECEPTOR KINASE (SERK) family RLKs regulate stomatal patterning downstream of EPF ligands and upstream of a MAP kinase cascade. EPF ligands induce the heteromerization of ERECTA and SERK family RLKs. SERK and ERECTA family RLKs transphosphorylate each other. In addition, SERKs associate with the receptor-like protein (RLP) TMM, a signal modulator of stomata development, in a ligand-independent manner, suggesting that ERECTA, SERKs, and TMM form a multiprotein receptorsome consisting of different RLKs and RLP perceiving peptide ligands to regulate stomatal  patterning. In contrast to the differential requirement of individual SERK members in plant immunity, cell-death control, and brassinosteroid (BR) signaling, all four functional SERKs are essential but have unequal genetic contributions to stomatal patterning, with descending order of importance from @entity22434 / @entity22434 to @entity68287 to @entity68288 to @entity68289 . Although BR signaling connects stomatal  development via multiple components, the function of SERKs in stomatal patterning is uncoupled from their involvement in BR signaling. Our results reveal that the SERK family is a shared  key module in diverse @entity958 signaling receptorsomes and that different combinatorial codes of individual SERK members regulate distinct functions.

Differential Function of XXXX SERK Family Receptor-like Kinases in Stomatal Patterning.

@entity68289 :: ('815862(Tax:3702)', 'Gene') :: ['SERK4'] @entity68288 :: ('843513(Tax:3702)', 'Gene') :: ['SERK1'] @entity958 :: ('3702', 'Species') :: ['Arabidopsis'] @entity68287 :: ('840320(Tax:3702)', 'Gene') :: ['SERK2'] @entity22434 :: ('829480(Tax:3702)', 'Gene') :: ['BAK1', 'SERK3']
@entity958 :: (3702,Species) :: ['Arabidopsis']
