The goal of the present work was to investigate possible risk factors for the poor response of some cases of chronic @entity1244 to endoscopic sinus surgery in spite of the precision of the surgical technique. Eleven adult @entity1 who were scheduled for revision endoscopic sinus surgery underwent a complete @entity566 workup. At the time of surgery, a tiny biopsy was taken from the maxillary sinus mucosa close to the middle turbinate. The specimens were processed for histochemical and transmission electron microscopic examination. Six @entity1 (55 per cent) proved to be @entity56 . Their sinus mucosa showed @entity1712 (6.1 cells/mm(2)), and mast cell degranulation. This proves that allergens can reach the sinus mucosa and have a direct impact on it. Another three @entity1 (27 per cent) were non- @entity56 but exhibited @entity33 (5.0 cells/mm(2)), and two of them showed mast cell degranulation. These @entity1 were diagnosed as having nonallergic rhinosinusitis with @entity1712 (NARSE). The nasal mucosa of the remaining two @entity1 did not reveal any characteristic pathological findings, and no pathologic diagnosis could be established for them. None of the @entity1 showed electron microscopic evidence of purulent inflammatory changes, and the bacterial cultures recovered normal respiratory flora in nine @entity1 (82 per cent). The present research spotlights the importance of @entity566 and nonallergic @entity1712 of the mucosa as possible risk factors that may degrade the results of endoscopic sinus procedures and discusses some pertinent pathological and clinical aspects.

Some risk factors for refractory chronic XXXX : an immunohistochemical and electron microscopic study.

@entity1244 :: ('MESH:D012852', 'Disease') :: ['sinusitis'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity1712 :: ('MESH:D004802', 'Disease') :: ['eosinophilic infiltration', 'eosinophilia'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergy'] @entity33 :: ('MESH:D052016', 'Disease') :: ['mucosal eosinophilia'] @entity56 :: ('MESH:D004342', 'Disease') :: ['allergic']
@entity1244 :: (MESH:D012852,Disease) :: ['sinusitis']
