BACKGROUND: The extended time window and theoretic reduction in @entity548 make mechanical strategies an attractive approach for the treatment of @entity1 with @entity385 . However, a limited availability of suitable animal models of @entity715 has hampered the study of novel endovascular interventions. The aim of the present study was to develop a new technique for site-specific placement of a @entity715 in a @entity235 model that would allow for the evaluation of mechanical thrombectomy and clot retrieval methods and the visualization of @entity715 dislocation or @entity1949 during angiographic manipulation. METHODS: Angiography and embolization with a preformed @entity715 were performed in 12 @entity235 . Under fluoroscopic guidance, an @entity887 ( @entity887 ) was anchored to the middle segment of the left vertebral artery (VA) via the left femoral arterial sheath. A preformed radiopaque clot was injected through the guide catheter into the left VA, via the contralateral femoral artery, proximal to the @entity887 . After 15 min of occlusion, the @entity887 was removed and persistent occlusion of the VA was documented angiographically. RESULTS: Angiography performed during the observation period confirmed the persistence of VA occlusion in each case, and displacement of the radiopaque clots did not occur during the 3-hour observation period. The technique allowed selective embolization of targeted vessels without @entity715 @entity1949 . CONCLUSION: This study demonstrates, for the first time, a @entity235 model of post-circulation @entity887 induced by autologous blood clot placement. This model can be rapidly formed and easily operated, and the site of @entity715 can be readily controlled.

A Novel XXXX Model of Acute Vertebral Artery Occlusion.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1949 :: ('MESH:D012892', 'Disease') :: ['fragmentation'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity235 :: ('9615', 'Species') :: ['canine', 'canines'] @entity887 :: ('MESH:D004617', 'Disease') :: ['embolism protection device', 'EPD', 'embolism'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus', 'thrombosis', 'cerebrovascular thrombosis'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity235 :: (9615,Species) :: ['Canine']
