PURPOSE: We describe first unprovoked @entity410 and newly diagnosed @entity302 at initial presentation, with a special emphasis on @entity302 , in a large cohort recruited in the mid-1990s in France. METHODS: The French Foundation for Research on @entity302 set up a network to conduct a prospective study of @entity1 with newly diagnosed unprovoked @entity410 . Information was provided by 243 @entity1 or adult neurologists. Four neurologists classified each case according to the International League Against @entity302 . First- @entity410 @entity1 and @entity1 with previously undiagnosed @entity410 were compared. RESULTS: Between May 1, 1995, and June 30, 1996, 1,942 @entity1 aged from 1 month to 95 years were identified: 926 (47.7%) with a single @entity410 and 1,016 (52.3%) with newly diagnosed @entity302 . All but 17 @entity1 had EEGs. In the first- @entity410 and newly-diagnosed- @entity302 groups, neuroimaging studies were performed in 78.2 and 68.3% of @entity1 , and medication prescribed in 54.1 and 89.6%, respectively. There were significant differences between the two groups with respect to age at onset and diagnosis, sex, etiology, several specific syndromes, as well as the type and presentation of initial @entity410 . In @entity1 for whom the first @entity410 was @entity410 , only sex, multiple @entity410 in a day or @entity159 , and cryptogenic localization-related syndrome differed between the two groups. CONCLUSIONS: Approximately half of @entity1 who first came to attention for an unprovoked @entity410 already met epidemiologic criteria for @entity302 . There were significant differences between the types of @entity1 with a first @entity410 and those with newly diagnosed @entity302 . One or several @entity410 at diagnosis did not influence the diagnostic assessment of the @entity1 but had a strong influence on the initiation of treatment.

Newly diagnosed unprovoked XXXX : presentation at diagnosis in CAROLE study. Coordination Active du R  seau Observatoire Longitudinal de l' Epilepsie.

@entity1 :: ('9606', 'Species') :: ['patients', 'child'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'convulsive', 'seizures'] @entity159 :: ('MESH:D013226', 'Disease') :: ['status epilepticus'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy syndromes', 'epilepsies', 'Epilepsy (ILAE) criteria', 'epilepsy', 'Epilepsy']
@entity302 :: (MESH:D004827,Disease) :: ['epileptic seizures']
