OBJECTIVE: To investigate the effects of @entity3303 on the morphology of saphenous veins (SVs) harvested during coronary artery bypass graft (CABG) surgery. METHODS: This experimental study was conducted at the Cardiovascular Surgery Department, Gazi University, Ankara, @entity233 , between May and September 2007. The SVs from 11 @entity1 who underwent CABG surgery were divided into 3 segments. Each segment from the same location of the grafts was allocated into 3 groups as control group (group C), physiologic saline group (group PS), and @entity3303 group (group L). @entity842 synthase (NOS), @entity842 (NO) pool, @entity224 dismutase (SOD), and @entity4466 reactive substances (TBARS) levels were measured in the samples from the groups. Histologic specimens were evaluated according to previously defined criteria, and scored accordingly. RESULTS: Histological examination of the grafts in groups L and C were similar, but histological scoring of grafts in group PS were statistically higher than group C (p=0.008). @entity842 synthase activity and NO pool were higher in groups L and PS than in group C (p=0.010). Super @entity8369 dismutase activity was higher in group L than in group PS (p=0.008). Super @entity8369 dismutase activity was lower in group PS than in group C (p=0.047). There was no significant difference between TBARS level in all groups. CONCLUSION: Our results indicate that primary damage might occur during surgery due to traumatic handling of the graft, and succeeding injuries could occur due to @entity63 -reperfusion injury during the waiting period. Adding @entity3303 to the preservation solution will protect later injury.

Effects of XXXX on membrane stabilization in harvested vein graft storage.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity233 :: ('9103', 'Species') :: ['Turkey'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity842 :: ('MESH:D009569', 'Chemical') :: ['Nitric oxide', 'nitric oxide'] @entity4466 :: ('MESH:C029684', 'Chemical') :: ['thiobarbituric acid'] @entity224 :: ('MESH:D013481', 'Chemical') :: ['super oxide'] @entity8369 :: ('CHEBI:25741', 'Chemical') :: ['oxide']
@entity3303 :: (MESH:D008012,Chemical) :: ['lidocaine']
