OBJECTIVE: To assess role of some inflammatory mediators in @entity1 with primary and recurrent @entity890 . Expression of @entity650 , transforming growth factor (TGF)-1, @entity442 , and @entity589 have been shown to be more intense in the primary group than the recurrent goup, but this mediators may be important aspects prognostic. METHODS: 19 @entity1 underwent primary and revision operations between June 1, 2009 and June 1, 2014, and they were included in this study. The 19 @entity1 ' intervertebral disc specimens obtained from the primary procedures and reoperations were evaluated. Expression of @entity650 , TGF-1, @entity442 , and @entity589 were examined immunohistochemically in the 38 biopsy tissues obtained from the primary and recurrent herniated intervertebral discs during the operation. RESULTS: For @entity650 expression in the intervertebral disc specimens, there was no difference between the groups. The immunohistochemical study showed that the intervertebral disc specimens in the primary group were stained intensely by TGF-1 compared with the recurrent group. Expression of @entity442 in the primary group was found moderate. In contrast, in the recurrent group of @entity1 was mild expression of @entity442 . The primary group intervertebral disc specimens were stained moderately by @entity589 compared with the recurrent group. CONCLUSION: The results of our prognostic evaluation of @entity1 in the recurrent group who were operated due to disc herniation suggest that mediators may be important parameters.

Role of Expression of Inflammatory Mediators in Primary and Recurrent XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity650 :: ('3569', 'Gene') :: ['IL-6'] @entity589 :: ('581', 'Gene') :: ['BAX', 'Bcl-2-associated X protein (BAX)'] @entity442 :: ('3479', 'Gene') :: ['insulin-like growth factor (IGF)-1', 'IGF-1'] @entity890 :: ('MESH:D007405', 'Disease') :: ['lumbar disc herniation']
@entity890 :: (MESH:D007405,Disease) :: ['Lumbar Disc Herniation']
