BACKGROUND: Although elevated serum @entity1133 and low serum @entity1372 have been shown to be associated with increased short-term (30-day) mortality following an @entity583 ( @entity583 ), little is known about the role of these biochemical markers as predictors of intermediate-term (1-year) re-hospitalisation. METHODS: Case notes of 90 consecutively admitted @entity1 discharged with a primary diagnosis of an @entity583 were retrospectively investigated. Baseline parameters were recorded and @entity1 ' clinical course following hospital discharge was carefully reviewed up to 1-year post- @entity583 . Multivariate logistic regression analysis was performed to determine the independent association between baseline parameters and 1-year re-hospitalisation. RESULTS: The mean age of the @entity1 was 62.8+/-1.38 years. Thirty @entity1 (33.3%) were re-hospitalised for cardiac-related events and three @entity1 (3.3%) died within 1 year of index @entity583 . Using stepwise regression analysis, after adjusting for all independent variables, admission total @entity165 (p=0.013) and @entity1133 (p=0.04) were found to be the only significant independent predictors of re-hospitalisation or @entity204 . Admission serum @entity1372 was non-significant (p=0.065), but only just. For each mmol/L increase in total @entity165 , a @entity1 was 2.18 times more likely to be re-hospitalised, while for each mmol/L increase in serum @entity1133 , a @entity1 was 1.32 times more likely to be re-hospitalised or die. When data were categorised based on high @entity1133 (> 7 mmol/L), high total @entity165 (> 5.0 mmol/L) and low @entity1372 (< 135 mmol/L) at admission, none of these variables showed any significant increased risk of re-hospitalisation or @entity204 . This suggests that these biochemical parameters were continuously associated with risk of re-hospitalisation through the whole range of serum concentrations. CONCLUSION: In this retrospective study, independent predictors of 1-year re-hospitalisation following an @entity583 include high serum @entity1133 , raised @entity165 levels and, possibly, reduced @entity1372 levels. These simple biomarkers can be included in @entity1 ' risk stratification when following post- @entity583 @entity1 in out- @entity1 clinics.

Serum @entity1133 and total @entity165 independently predict re-hospitalisation with a cardiac-related event following an acute XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1133 :: ('MESH:D014508', 'Chemical') :: ['urea'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST-elevation myocardial infarction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity583 :: (MESH:D009203,Disease) :: ['ST-elevation myocardial infarction']
