BACKGROUND: Most reports regarding the treatment of @entity259 originate from university referral centers. In this article, we report our experience in managing @entity259 of follicular cell origin at a non-university institution over a 26-year period. STUDY DESIGN: We reviewed the medical records of all @entity1 treated for @entity259 at the Gundersen/Lutheran Medical Center from 1969 to 1995. Histologic types, demographic and clinical characteristics, laboratory results, treatment, complications, and followup observations were tabulated. Risk was assigned according to the age, presence of distant @entity3 , extent of the @entity5 , and site of the @entity5 (AMES) staging system. RESULTS: The histologic classification was as follows: papillary, 139; follicular, 24; H  rthle cell, 14; and anaplastic, 11. Low-risk lesions were identified in 96%, 79%, and 71% of the @entity1 with papillary, follicular, and H  rthle cell (collectively designated differentiated) @entity189 , respectively. We treated 60% of our @entity1 with @entity259 with near-total or total thyroidectomy. Clinically involved cervical lymph nodes were removed singly or by modified neck dissection. We frequently ablated thyroid remnants after operation with 29.9 mCi (1,110 MBq) of 131I, after which we treated the @entity1 with suppressive doses of @entity1955 . @entity1 were evaluated yearly with thyroglobulin measurements and, in some high-risk @entity1 , with total-body 131I scans. @entity5 recurred in 13%, 8%, and 7% of our @entity1 with papillary, follicular, and H  rthle cell @entity189 , respectively. Only three @entity1 died of @entity259 ; eight are alive with @entity5 . In @entity259 , cervical lymph node @entity3 , local invasion, and distant @entity3 were present in 18%, 64%, and 45% of @entity1 at the time of initial evaluation. Total or near-total thyroidectomy was possible in only four of nine @entity1 treated surgically. External radiation (11 @entity1 ) and chemotherapy (two @entity1 ) were used. Additional @entity3 developed in 45% of the @entity1 , and nine @entity1 died within a year. Permanent @entity261 or hoarseness complicated 2.7% of the thyroid operations. CONCLUSIONS: Although our followup was relatively short, the results of treating @entity259 by general surgeons at a nonuniversity hospital compare favorably with results obtained from university referral centers.

Management of XXXX of follicular cell origin: Gundersen/Lutheran Medical Center, 1969-1995.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumor', 'Cancer', 'malignancy'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity1955 :: ('MESH:D013974', 'Chemical') :: ['levothyroxine'] @entity261 :: ('MESH:D007011', 'Disease') :: ['hypoparathyroidism'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity259 :: ('MESH:D013964', 'Disease') :: ['anaplastic thyroid cancer', 'thyroid cancer', 'differentiated thyroid cancer']
@entity259 :: (MESH:D013964,Disease) :: ['thyroid cancer']
