CONTEXT: @entity31483 (EC) is a fast-acting vapo-coolant spray that provides rapid, transient, local analgesia for minor invasive procedures. Although the application of EC has decreased, it can be used as a cryoanalgesic agent in minor surgical procedures. OBJECTIVE: Despite the widespread use of EC as a local anesthetic, there are few reported cases of serious adverse side effects. MATERIAL AND METHODS: We report a 67-year old otherwise healthy @entity1 who underwent excision of a @entity1185 on his superior right eyelid by a general practitioner at a primary care center. The lesion was removed by curettage after slight freezing with EC spray. This chemical agent was applied without the adequate eye protection, and eight hours later the @entity1 presented an acute frost injury of ocular surface. RESULTS: Urgent treatment included copious irrigation of the affected eye, especially the conjunctival fornices, @entity228 ( @entity229 ) and antibiotic ( @entity5154 ) ointment. A week later, the eyelid lesion and keratoconjunctivitis had resolved but evidence of early cicatrization involving the inferior conjucntival fornix and symblepharon formation were present. DISCUSSION: To the best of our knowledge, this is the first reported case of an acute burn of the ocular surface following EC spray exposure. CONCLUSION: EC should be avoided for short-term local anesthesia in the periocular region to prevent this serious complication.

Ocular surface frostbite secondary to XXXX spray.

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity31483 :: ('MESH:D005018', 'Chemical') :: ['Ethyl chloride'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity1185 :: ('MESH:D010212', 'Disease') :: ['papilloma'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['corticosteroid'] @entity5154 :: ('MESH:D009355', 'Chemical') :: ['neomycin']
@entity31483 :: (MESH:D005018,Chemical) :: ['ethyl chloride']
