1. The swelling and solubilization of foetal and adult @entity291 ligament over a range of pH values has been investigated. 2. Maximum swelling occurs at pH2.7 and pH8.5 for both types of ligament. Abover pH13 complete solubilization occurs. 3. Considerably greater swelling and solubilization occurs with foetal ligament below pH12. 4. The presence of 2m- @entity2827 markedly suppresses both swelling and solubilization. Above 1n- @entity7159 actual dehydration occurs and little or no protein is extracted. 5. It is suggested that the intermolecular cross-links in a considerable proportion of foetal @entity37544 are weak and that extraction with aqueous salt solution at pH8.5 would provide optimum conditions for extracting soluble proteins, including soluble @entity37544 if this is present.

The swelling of XXXX ligamentum nuchae as a function of pH.

@entity37544 :: ('280781(Tax:9913)', 'Gene') :: ['elastin'] @entity2827 :: ('MESH:D012965', 'Chemical') :: ['sodium chloride'] @entity291 :: ('9913', 'Species') :: ['bovine'] @entity7159 :: ('MESH:D012972', 'Chemical') :: ['sodium hydroxide']
@entity291 :: (9913,Species) :: ['bovine']
