PURPOSE: Extracorporeal irradiation (ECI) has been used selectively in the management of primary @entity3478 since 1996. We report our techniques for ECI and the short-term oncologic and orthopedic outcomes. METHODS AND MATERIALS: Sixteen @entity1 with primary @entity3478 were treated with ECI from 1996 to 2000. The median age was 14 years. The histologic diagnoses were @entity2828 (11), @entity421 (4) and @entity511 (1). The treated sites were femur (7), tibia (4), humerus (2), ilium (2), and sacrum (1). Following induction chemotherapy in Ewing's @entity242 and @entity421 , en bloc resection of the @entity5 and @entity5 -bearing bone was performed. A single dose of 50 Gy was delivered to the bone extracorporeally using either a linear accelerator (9 cases) or a blood product irradiator (7 cases). The orthopedic outcome was recorded using a standard functional scale. RESULTS: At a median follow-up of 19.5 months, there were no cases of local recurrence or graft failure. One @entity1 required amputation due to @entity6275 . For the 10 @entity1 with follow-up greater than 18 months, the functional outcomes were graded good to excellent. CONCLUSION: The short-term oncologic and orthopedic results are encouraging and suggest that ECI provides a good alternative for reconstruction in limb conservative surgery in selected @entity1 . This technique should only be used in a multidisciplinary setting, where careful follow-up is available to assess the long-term outcomes.

Extracorporeal irradiation for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2828 :: ('MESH:D012512', 'Disease') :: ["Ewing's sarcoma"] @entity6275 :: ('MESH:C535456', 'Disease') :: ['chronic osteomyelitis'] @entity511 :: ('MESH:D002813', 'Disease') :: ['chondrosarcoma'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcomas'] @entity3478 :: ('MESH:D001859', 'Disease') :: ['malignant bone tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity421 :: ('MESH:D012516', 'Disease') :: ['osteosarcoma']
@entity3478 :: (MESH:D001859,Disease) :: ['malignant bone tumors']
