BACKGROUND: Coronary stenting in @entity1 has been associated with worse results in terms of morbidity, mortality, and restenosis rate in the bare-metal stent @entity7971 , possibly due to higher risk profile and smaller coronary vessels. Although drug-eluting stents have equalized clinical results, no data are available on long-term outcomes between sexes. OBJECTIVES: To evaluate the role of sex in acute, mid-term, and long-term clinical outcome after @entity3446 -eluting stent (SES) implantation. METHODS: We retrospectively evaluated 1186 @entity1 , 970 (81.8%) male and 216 (18.2%) female, treated with SES implantation between April 2002 and December 2005. RESULTS: @entity1 were older (P=0.049), more likely to have @entity101 (43.5 vs. 33.7%, P=0.006), @entity66 (63.9 vs. 42.5%, P=0.03), and @entity1459 (16.6% vs. 9.2%, P=0.001) and more frequently received small ( <= 2.75 mm) vessel stenting (39.3 vs. 28.2%, P=0.001). The two groups were similar for lesion and procedural characteristics. Overall, the stent @entity715 rate was 0.4% (0.5% in @entity1 vs. 0.3% in @entity1 , P=not significant). At 6-month follow-up, no significant difference in major adverse cardiac event was observed. Long-term follow-up (median time 33.2 months), available in 180 (83.3%) @entity1 and 720 (75%) @entity1 , showed higher angina recurrence rate (17.7 vs. 11%, P=0.013), percutaneous coronary re-intervention (16.1 vs. 8.7%, P=0.001) and target vessel revascularization (3.9 vs. 0.9%, P=0.001) in @entity1 compared with @entity1 . Late stent @entity715 , need for coronary artery bypass grafting, and mortality were similar in both groups. CONCLUSION: No sex difference was observed in acute and 6-month outcome after SES implantation despite older age, more unstable clinical presentation, and more frequent small vessel stenting in @entity1 . However, long-term clinical follow-up (up to 5 years) in @entity1 showed higher symptom recurrence and target vessel revascularization rate but no difference in overall major adverse @entity299 .

Sex difference in long-term clinical outcome after XXXX -eluting stent implantation.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients', 'Women'] @entity7971 :: ('26284', 'Gene') :: ['era'] @entity66 :: ('MESH:D004194', 'Disease') :: ['single-vessel disease'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity3446 :: ('MESH:D020123', 'Chemical') :: ['sirolimus'] @entity1459 :: ('MESH:D000789', 'Disease') :: ['unstable angina'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity3446 :: (MESH:D020123,Chemical) :: ['sirolimus']
