INTRODUCTION: In every 7th @entity1 with @entity14 has already spread beyond intestinal wall into surrounding organs. @entity1 AND METHODS: Between 01. 01. 1990 and 31. 12. 1998 763 @entity1 with @entity14 were treated at our surgical department. 166 @entity1 (23 %) presented with @entity5 contiguous or adherent to adjacent organs (cT4). RESULTS: In most cases @entity5 was localized in colon (109 @entity1 , 66 %), in 57 @entity1 (34 %) @entity5 was found in rectum. Potenzial curative resection (R0) was possible in 67 @entity1 (40 %). 66 @entity1 (40 %) had microscopic (R1) or gro beta residual disease (R2) and in 33 @entity1 only palliative surgery was possible. Extended resection of adjacent organs was performed in 97 % in the group with curative resection. 11 @entity1 (8 %) died after multivisceral resection. The 5-year survival for curative resection was 57 %, for @entity1 with microscopic or gro beta residual disease 9 months and for palliative surgery only 4 months. CONCLUSION: Optimistic longterm results in advanced @entity14 can only be achieved after curative resection. After incomplete resection or palliative surgery median life expectancy is extremely poor.

[Results of the surgical therapy in advanced XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer', 'colorectal cancer tumor']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal cancer']
