INTRODUCTION: Primary gastrointestinal tract @entity1073 is very rare. There is paucity of literature regarding natural history and outcome of this unusual entity. AIMS AND OBJECTIVES: The aim of the present study was to analyze clinical profile, epidemiological parameters, and outcome of primary @entity1073 @entity1 treated at our institute. MATERIALS AND METHODS: This was a retrospective observational study of consecutive @entity1 diagnosed with primary @entity1073 at our institute between 2001 and 2012. RESULTS: A total of seven @entity1 , all males with a median age of 67.7  years, were diagnosed with primary @entity1073 . Sites involved were the stomach, colon, and rectum. Blastoid and diffuse variants were observed in three @entity1 each, and one @entity1 had nodular pattern. Five @entity1 received @entity786 , @entity632 , @entity1891 , and @entity617 ( @entity3726 ) chemotherapy. Only one @entity1 achieved complete remission and remained disease free for 21  months before being lost to follow up. The remaining four @entity1 had inadequate response to @entity3726 chemotherapy with a median survival of 6  months. @entity786 , @entity1891 , @entity617 (CVP) was given to one @entity1 in view of poor performance status. He had progressive disease and died after first cycle of chemotherapy. One @entity1 is currently undergoing treatment and receiving rituximab with chemotherapy. CONCLUSIONS: Primary @entity1073 is highly aggressive with the Mantle Cell Lymphoma International Prognostic Index (MIPI) scores in high-risk group; survival is poor compared to nodal @entity1073 involving the gastrointestinal tract; @entity1 respond poorly to @entity3726 chemotherapy. As majority of @entity1 are elderly and not eligible for transplant, the use of rituximab in remission induction and maintenance should be considered to improve outcome of these @entity1 .

Primary XXXX : A Retrospective Study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity632 :: ('MESH:D004317', 'Chemical') :: ['adriamycin'] @entity3726 :: ('1649', 'Gene') :: ['CHOP'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide', 'Cyclophosphamide'] @entity1891 :: ('MESH:D014750', 'Chemical') :: ['vincristine'] @entity1073 :: ('MESH:D020522', 'Disease') :: ['mantle cell lymphoma', 'gastrointestinal mantle cell lymphoma'] @entity617 :: ('MESH:D011239', 'Chemical') :: ['prednisolone']
@entity1073 :: (MESH:D020522,Disease) :: ['Gastrointestinal Mantle Cell Lymphoma']
