BACKGROUND: @entity74 ( @entity74 ) critically impact social cognition in @entity1 with @entity161 . @entity74 can affect both relationships with @entity1 familiar to the @entity1 and the @entity1 's relationship with himself, in the case of a self-disorder. Skin conductance response (SCR) studies have shown that familiar and unknown faces elicit the same emotional response in @entity1 with @entity161 with @entity10751 . Moreover, in control subjects, one's own face and familiar faces have been shown to activate strongly overlapping neural networks, suggesting common processing. The aim of the present study was to determine whether the mechanisms involved in processing one's own and familiar faces are similarly impaired in @entity1 with @entity161 , suggesting a link between them. METHOD: Twenty-eight @entity1 with @entity161 were compared with twenty control subjects. Three face conditions were used: specific familiar, self and unknown. The task was to indicate the gender of the faces presented randomly on a screen during SCR recording. Face recognition was evaluated afterwards. RESULTS: Control subjects exhibited similar SCRs for the familiar and self-conditions, which were higher than the responses elicited by the unknown condition, whereas @entity1 with @entity161 exhibited no significant differences between the three conditions. CONCLUSION: @entity1 with @entity161 have a core defect of both self and familiarity that is emphasised by the lack of an increased SCR upon presentation with either self or familiar stimuli. Familiarity with specific familiar faces and one's own face may be driven by the same mechanism. This perturbation may predispose @entity1 with @entity161 to @entity8143 and, in particular, to general @entity74 .

What is more familiar than I? Self, other and familiarity in XXXX .

@entity1 :: ('9606', 'Species') :: ['Persons', 'patient', 'people', 'persons'] @entity10751 :: ('MESH:D004402', 'Disease') :: ['FD'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia'] @entity74 :: ('MESH:D030342', 'Disease') :: ['familiarity disorder', 'Familiarity disorders', 'FDs'] @entity8143 :: ('MESH:D063726', 'Disease') :: ['delusions']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
