Skin microcirculation and skin temperature of 10 healthy subjects (6 @entity1 and 4 @entity1 , 20-44 yr of age) without any @entity455 were registered when a thermoindifferent tap water iontophoresis was applied. The aim of this controlled study was to evaluate the development of @entity272 after the intake of 500 mg of @entity117 ( @entity1281 ). The measurement was conducted by laser-Doppler flowmetry on the proximal forearm. The skin temperature was measured before and after the treatment by an infrared thermometer. In all @entity1 there was an intense erythema on the side of the cathode and only a modest one on the side of the anode. Without ASA preliminary treatment, the cutaneous flow showed an increase of 106% at the anodal side and that of 834% at the cathodal side (P < 0.001). After ending tap water iontophoresis, the skin temperature increased more on the cathode side than on the anode side (P < 0.001). After the intake of 500 mg ASA, the increase of the flow was 78% at the anode and 88% at the cathode. The comparison of the skin microcirculation did not show any differences at the anodal side when @entity117 was taken before, but a strong suppression of the @entity5105 at the cathodal side was observed after the intake of ASA. There is a direct influence of @entity117 on the induction of the @entity13624 caused by a @entity5105 . The intensity of the induced erythema correlates with the analgesic effects of constant current treatment. An attenuation of the electrotherapeutic analgesia is possible.

Reduced @entity272 during tap water iontophoresis after intake of XXXX .

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'persons'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular diseases'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['acetylsalicylic acid'] @entity5105 :: ('MESH:D004890', 'Disease') :: ['galvanic erythema'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin hyperemia'] @entity1281 :: ('CHEBI:15365', 'Chemical') :: ['ASA'] @entity13624 :: ('MESH:D020078', 'Disease') :: ['neurogenic inflammation']
@entity117 :: (MESH:D001241,Chemical) :: ['acetylsalicylic acid']
