The rarity or the asymptomatic @entity5 results in a lack of epidemiological studies on their incidence and survival patterns. The aim of this study was to describe the incidence, prevalence and @entity5 using a large database, which includes @entity5 @entity1 diagnosed from 1978 to 2002, registered in 89 population-based @entity5 registries (CRs) with follow-up until 31st December 2003. These data give an unique overview of the @entity8703 in Europe. A list of @entity5 entities based on the third International Classification of Diseases for Oncology was provided by the project Surveillance of rare @entity5 in Europe (RARECARE) project. Over 33,594 cases of endocrine @entity189 were analysed in this study. Incidence rates increased with age and were highest in @entity1 65 years of age or older. In 2003, more than 315,000 @entity1 in the EU (27 countries) were alive with a past diagnosis of a @entity189 of endocrine organs. The incidence of @entity977 equalled four per 1,000,000 @entity1 years and showed the strongest decline in survival with increasing age. @entity259 showed the highest crude incidence rates (four per 100,000 @entity1 years) and was the only entity with a gender difference: (female-to-male ratio: 2:9). @entity3243 was the rarest endocrine entity with two new cases per 10,000,000 @entity1 years. For @entity4304 , the most remarkable observations were a higher survival for @entity1 compared to @entity1 (40% compared to 32%, respectively) and a particularly low relative survival of 24% in @entity1 65 years of age or older. More high quality studies on rare @entity5 , with additional information, e.g. on stage and therapeutic approach, are needed and may be of help in partly explaining the observed variation in survival.

XXXX of endocrine organs: results of the RARECARE project.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients', 'person', 'persons'] @entity5 :: ('MESH:D009369', 'Disease') :: ['character of endocrine tumours', 'cancers', 'cancer', 'survival of endocrine tumours', 'tumour'] @entity8703 :: ('MESH:D004701', 'Disease') :: ['burden of endocrine carcinomas'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas', 'carcinoma'] @entity977 :: ('MESH:D010911', 'Disease') :: ['pituitary carcinoma'] @entity3243 :: ('MESH:D010282', 'Disease') :: ['Parathyroid carcinoma'] @entity259 :: ('MESH:D013964', 'Disease') :: ['Thyroid cancer'] @entity4304 :: ('MESH:D000310', 'Disease') :: ['adrenal carcinoma']
@entity189 :: (MESH:D002277,Disease) :: ['Carcinoma']
