AIM: The aim of this study is to investigate premorbid sleep reactivity as a vulnerability to incident @entity1442 ( @entity1442 ), and related changes in @entity308 as well as @entity148 following a transition to a rotating shifts work schedule. METHODS: This is a longitudinal study with two waves of data collection. The community-based sample included normal sleeping non-shift workers (N   =   96; 62.5% female; 47.9        13.3 years) without a lifetime history of @entity22 or baseline excessive @entity25 who transitioned to rotating shift work one year later. @entity1 reported demographic characteristics, trait sleep reactivity on the Ford Insomnia Response to Stress Test, @entity308 symptoms on the Quick Inventory of @entity308 Symptomatology, and @entity148 on the Beck Anxiety Inventory. @entity1442 was determined based on significant @entity25 and/or excessive @entity25 in the context of working in a rotating-shift schedule. RESULTS: Analyses revealed that the odds were over five times greater for highly sleep-reactive individuals to develop @entity1442 after transitioning to rotating shifts (OR   =   5.59, p   =   0.04). Nearly 90% of @entity1 who suffered from @entity1442 were accurately identified as high risk at one year before disease onset. Furthermore, individuals who developed @entity1442 reported greater increases in symptoms of @entity308 and @entity148 . Finally, analyses revealed significant indirect effects wherein high sleep reactivity increased risk for @entity1442 , which led to greater severity of @entity148 and @entity308 symptoms. CONCLUSIONS: The Ford Insomnia Response to Stress Test (FIRST) accurately identifies a focused target population in which the premorbid psychobiological processes complicit in @entity1442 onset and progression, as well as shift work-related @entity308 and @entity148 changes, can be better investigated, thus improving future preventative efforts.

Shift work disorder, @entity308 , and XXXX in the transition to rotating shifts: the role of sleep reactivity.

@entity1 :: ('9606', 'Species') :: ['participants', 'Participants'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression', 'depression'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['shift work disorder', 'SWD'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety symptoms', 'anxiety'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleepiness', 'daytime sleepiness', 'sleep disturbance'] @entity22 :: ('MESH:D007319', 'Disease') :: ['insomnia']
@entity148 :: (MESH:D001008,Disease) :: ['anxiety']
