UNASSIGNED: @entity28 has been previously suggested as an adverse prognostic marker in @entity1 with @entity3052 . To evaluate the relationship between @entity28 and clinical outcome, disease-free survival (DFS) and @entity1349 ( @entity1349 ), in @entity1 with @entity3052 ( @entity3052 ), including @entity2799 ( @entity2799 ), we performed a pooled analysis of four CALGB (Alliance) clinical trials. Our study included 446 @entity1 with @entity2799 from CALGB 9710, and 1,648 @entity1 between 18 and 60 years of age with non- @entity2799 @entity3052 from CALGB 9621, 10503, and 19808. @entity28 was defined as BMI >= 30 kg/m(2) . Multivariate Cox proportional-hazard regression models were fitted for DFS and @entity1349 . @entity28 was seen in 50% and 38% of @entity2799 and non- @entity2799 @entity3052 @entity1 , respectively. In @entity2799 @entity1 , @entity28 was associated with worse DFS (HR 1.53, 95% CI 1.03-2.27; P = 0.04) and @entity1349 (HR 1.72, 95% CI 1.15-2.58; P = 0.01) after adjusting for age, sex, performance status, race, ethnicity, treatment arm and baseline white blood cell count. @entity28 was not significantly associated with DFS or @entity1349 in the non- @entity2799 @entity3052 @entity1 . In conclusion, our study indicates that @entity28 has significant prognostic value for DFS and @entity1349 in @entity2799 @entity1 , but not for non- @entity2799 @entity3052 @entity1 . Am. J. Hematol. 91:199-204, 2016.    2015 Wiley Periodicals, Inc.

Relationship between @entity28 and clinical outcome in adults with XXXX : A pooled analysis from four CALGB (alliance) clinical trials.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2799 :: ('MESH:D015473', 'Disease') :: ['APL', 'acute promyelocytic leukemia'] @entity28 :: ('MESH:D009765', 'Disease') :: ['Obesity', 'obesity'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['acute myelogenous leukemia', 'AML', 'acute leukemia'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity3052 :: (MESH:D015470,Disease) :: ['acute myeloid leukemia']
