OBJECTIVE: To determine the frequency and the characteristics of distal musculoskeletal manifestations in @entity2760 ( @entity2760 ). METHODS: Prospective followup study of 177 consecutive @entity1 meeting clinical criteria for @entity2760 , diagnosed over a 5-year period in 2 rheumatology secondary referral centers in Italy. RESULTS: Seventy-nine of the 177 @entity1 (45%) had distal musculoskeletal manifestations. @entity625 occurred in 45 @entity1 (25%), @entity923 in 24 (14%), distal extremity swelling with pitting @entity4 in 21 (12%), and distal @entity2762 in 5 (3%). These manifestations were usually associated with @entity2760 proximal symptoms (69%); however, 31% of the episodes represented isolated relapse/recurrence at distal sites. Distal symptoms responded promptly to corticosteroids. No evidence of @entity85 , @entity2681 , or development of @entity309 was observed during the followup. The group of @entity1 with @entity625 included a higher proportion of females, had a longer duration of therapy, and had more relapses/ recurrences. @entity1 who had distal extremity swelling with pitting @entity4 had a higher age at disease onset, a shorter duration of therapy, and lower initial and cumulative @entity229 doses. CONCLUSION: Inflammatory involvement of distal articular and/or tenosynovial structures occurs in approximately half of the cases of @entity2760 . @entity625 is associated with more severe disease, while distal extremity swelling with pitting @entity4 appears to identify a more benign disease subset.

Distal musculoskeletal manifestations in XXXX : a prospective followup study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity625 :: ('MESH:D001168', 'Disease') :: ['peripheral arthritis', 'Peripheral arthritis'] @entity2681 :: ('MESH:D014077', 'Disease') :: ['erosions'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity2760 :: ('MESH:D011111', 'Disease') :: ['polymyalgia rheumatica', 'PMR'] @entity923 :: ('MESH:D002349', 'Disease') :: ['carpal tunnel syndrome'] @entity85 :: ('MESH:D009140', 'Disease') :: ['joint deformities'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis'] @entity2762 :: ('MESH:D013717', 'Disease') :: ['tenosynovitis']
@entity2760 :: (MESH:D011111,Disease) :: ['polymyalgia rheumatica']
