BACKGROUND: The aim of this study was to investigate the correlation between @entity5433 in @entity15 ( @entity15 ) and @entity409 evaluated with the vestibular evoked myogenic potentials (VEMP) score and conventional MRI. METHODS: Forty-five @entity1 with the diagnosis of @entity922 ( @entity922 ) suggestive of @entity15 were enrolled. VEMP, heart rate, and blood pressure responses to the Valsalva maneuver, heart rate response to deep @entity1353 , and @entity158 provoked head-up tilt table test, as well as brain and spinal cord MRI were performed. RESULTS: There was no difference in the VEMP score between @entity1 with and without signs of sympathetic or parasympathetic dysfunction. However, @entity1 with @entity1163 had significantly lower VEMP score compared to @entity1 without @entity1163 (p<0.01). @entity1 with @entity551 ( @entity551 ) showed a trend of higher VEMP score compared to @entity1 without @entity551 (p=0.06). There was no difference in the presence of lesions in the brainstem or cervical spinal cord between @entity1 with or without any of the studied autonomic parameters. The model consisting of a VEMP score of  <=5 and normal MRI of the midbrain and cervical spinal cord has sensitivity and specificity of 83% for the possibility that the @entity1 with @entity15 can develop @entity1163 . CONCLUSIONS: Pathophysiological mechanisms underlying functional and structural @entity3002 in @entity15 differ significantly. While preserved brainstem function is needed for development of @entity2383 like @entity551 could be associated with @entity409 .

@entity409 protects against @entity1163 in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['breathing'] @entity409 :: ('MESH:D008107', 'Disease') :: ['brainstem dysfunction'] @entity3002 :: ('MESH:D009421', 'Disease') :: ['disorders of autonomic nervous system'] @entity1163 :: ('MESH:D013575', 'Disease') :: ['syncope'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity5433 :: ('MESH:C563939', 'Disease') :: ['autonomic dysfunction'] @entity551 :: ('MESH:D007022', 'Disease') :: ['OH', 'orthostatic hypotension'] @entity15 :: ('MESH:D009103', 'Disease') :: ['MS', 'multiple sclerosis'] @entity922 :: ('MESH:D013568', 'Disease') :: ['clinically isolated syndrome', 'CIS'] @entity2383 :: ('MESH:D028361', 'Disease') :: ['syncope, structural disorders']
@entity15 :: (MESH:D009103,Disease) :: ['multiple sclerosis']
