OBJECTIVES: Our study was designed to visually represent recurrence patterns after surgery for @entity1149 ( @entity1149 ) with the use of event dynamics and to clarify postoperative follow-up methods based on the times of recurrence. METHODS: A total of 829 @entity1 with @entity1149 who underwent complete pulmonary resection from 2005 to 2007 in 9 hospitals affiliated with the Yokohama Consortium of Thoracic Surgeons were studied. Event dynamics, based on the hazard rate, were evaluated. Only first events involving the development of distant @entity3 , local recurrence or both were considered. The effects of sex, histological type, pathological stage and age were studied. RESULTS: The hazard rate curve displayed an initial surge that peaked about 6-8 months after surgery. The next distinct peak was noted at the end of the second year of follow-up. On non-parametric kernel smoothing, the maximum peak was found 6-8 months after surgery in @entity1 . In @entity1 , the highest peak occurred 22-24 months after surgery, which was about 16 months later than the peak in @entity1 . The peak timing of the hazard curve was not affected by histological type, pathological stage or age in either sex. CONCLUSIONS: Our results suggest that the timing of recurrence after surgery for @entity2 is characterized by a bimodal pattern, and the times with the highest risk of recurrence were suggested to differ between @entity1 and @entity1 . Postoperative follow-up strategies should be based on currently recommended follow-up programmes, take into account the recurrence patterns of @entity2 , and be modified as required to meet the needs of individual @entity1 .

Postoperative follow-up strategy based on recurrence dynamics for XXXX   .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small-cell lung cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer']
@entity1149 :: (MESH:D002289,Disease) :: ['non-small-cell lung cancer']
