UNASSIGNED: Even though the pathophysiology is not completely understood, @entity76 has been invoked in essential @entity400 (ET). We evaluated @entity76 in ET with the presence of perverted head-shaking (pHSN) and positional downbeat nystagmus (pDBN) which are known to reflect @entity76 . First, we reviewed the videooculography (VOG) of 185 @entity1 with ET from March 2007 to April 2010. Seventeen of 28 @entity1 with pHSN and pDBN were followed up for at least a 1.8-year interval from baseline to determine the clinical course. And then, we recruited 52 consecutive @entity1 with ET and compared their ocular motor findings with 51 normal controls using VOG. Among the 185 @entity1 with ET, 28 (15.1  %) showed pHSN (n   =   23, 12.4  %) or pDBN (n   =   8, 4.3  %). Seventeen of them who were followed up did not develop @entity304 or other @entity51 during the observation period. The subsequent case-control study showed a higher prevalence of pHSN or pDBN (11/52, 21.2  %, pHSN in nine and pDBN in five) in @entity1 with ET than in the normal controls (2/51, 3.9  %, pHSN only, P   =   0.015). The @entity400 rating scale or involved body sites did not differ between the @entity1 with and without pHSN/pDBN. pHSN and pDBN were more common in @entity1 with ET than in the normal controls. This result supports that @entity76 is associated with ET.

Perverted Head-Shaking and Positional Downbeat Nystagmus in Essential XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity304 :: ('MESH:D010302', 'Disease') :: ['Parkinsonism'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurologic deficits'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity76 :: ('MESH:D002526', 'Disease') :: ['cerebellar dysfunction']
@entity400 :: (MESH:D014202,Disease) :: ['Tremor']
