BACKGROUND AND OBJECTIVES: @entity5572 ( @entity5572 ) is a well-described disease in the medical literature; however, information about its characteristics and outcome in the Middle East is lacking. We compared the mode of presentation, risk factors, management and outcome of @entity5572 @entity1 in Saudi Arabia with cases from the United Kingdom (UK). DESIGN AND SETTING: Retrospective review of @entity5572 @entity1 from three tertiary care centers (2 from Saudi Arabia and 1 from the UK) over a period of 10 years, from 1995 to 2005. @entity1 AND METHODS: Data collected included demographic characteristics; clinical presentation; biochemical, microbiological and radiological findings; treatment modalities; and outcome. RESULTS: A total of 83 @entity1 were diagnosed with @entity5572 , including 48 @entity1 from Saudi Arabia and 35 @entity1 from the UK. The mean (SD) age was 45.2 (20.3) years for those from Saudi Arabia and 55.4 (18.8) years for those from the UK (P=.022). The majority of the @entity1 were males (70% from Saudi Arabia and 80% from the UK). Upper @entity490 and @entity221 were the commonest symptoms, each reported in 87% of the cases. Alkaline phosphatase elevation was the commonest liver function abnormality, seen in 66 (80%) @entity1 . Organisms were isolated in 43 (52%) cases and the majority of these were coliforms (58%). @entity9111 occurred in 19 (23%) @entity1 and all of those @entity1 were either from or had traveled recently to the Indian subcontinent. Complete resolution of the abscesses was achieved in 66 (80%) @entity1 with @entity1173 and/or antibiotics, and 9 (10.8%) @entity1 died. On multivariate analysis, underlying @entity5 , @entity551 and chest signs at presentation were predictors of poor outcome (P=.008, .029 and .001, respectively). CONCLUSIONS: Successful resolution of @entity5572 is achievable in the majority of the cases, although underlying @entity5 is associated with poor outcome. @entity9111 must be considered in @entity1 with a history of travel to endemic areas.

XXXX presentation and management in Saudi Arabia and the United Kingdom.

@entity5572 :: ('MESH:D008100', 'Disease') :: ['Liver abscess', 'LA'] @entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancy'] @entity9111 :: ('MESH:D008101', 'Disease') :: ['Amebic liver abscesses'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity1173 :: ('MESH:D053120', 'Disease') :: ['aspiration']
@entity5572 :: (MESH:D008100,Disease) :: ['Liver abscess']
