BACKGROUND: Intra-articular @entity228 injection is a common therapy for @entity2585 , but there is a lack of prospective randomized controlled studies analyzing the efficacy of single injections applied blindly to accelerate improvement in @entity158 and function. HYPOTHESIS: In @entity1 with @entity2585 , a single intra-articular @entity228 injection without image control applied before the beginning of a physical therapy program will accelerate @entity158 relief and recovery of function compared with oral nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy. STUDY DESIGN: Randomized controlled trial; Level of evidence, 1. METHODS: A total of 74 @entity1 with primary @entity2585 in the freezing stage were randomized to receive either intra-articular injections with @entity5935 or oral NSAIDs. Clinical outcome was documented at baseline and after 2, 4, 8, and 12 weeks and comprised a visual analog scale (VAS) for @entity158 , the American Shoulder and Elbow Surgeons (ASES) Shoulder Score, the abbreviated Constant-Murley score, and the abbreviated Disabilities of the Arm, Shoulder and Hand (QuickDASH) score for function. Passive range of motion was measured with a goniometer. RESULTS: @entity1 treated with @entity228 injections achieved faster @entity158 relief compared with control @entity1 during the first 8 weeks after treatment (P < .001). However, no significant difference in @entity158 was observed among the groups at final follow-up. Likewise, shoulder function and motion improved significantly in both groups at all follow-up points. Shoulder function scores and most motion parameters improved faster in the injection group up to week 8 (P < .001). Again, no significant differences in function or motion were seen at final follow-up. CONCLUSION: In @entity1 with @entity2585 , a single @entity228 injection applied without image control provides faster @entity158 relief and earlier improvement of shoulder function and motion compared with oral NSAIDs.

@entity228 Injections Accelerate Pain Relief and Recovery of Function Compared With Oral NSAIDs in XXXX With @entity2585 : A Randomized Controlled Trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5935 :: ('MESH:D001623', 'Chemical') :: ['betamethasone'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['corticosteroid'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity2585 :: ('MESH:D002062', 'Disease') :: ['adhesive capsulitis']
@entity1 :: (9606,Species) :: ['Patients']
