CONTEXT: Thyroid @entity792 is a recognized disorder in pregnancy and is associated with a number of adverse pregnancy outcomes. AIM: This study set out to determine the relationship between pregnancy and @entity1669 in Nigerian @entity1 . SETTINGS AND DESIGN: This was an analytical cross-sectional study carried out in a tertiary hospital in South Western Nigeria with a total study population of 108 pregnant and 52 nonpregnant @entity1 . SUBJECTS AND METHODS: Serum thyroid stimulating hormone, free @entity1955 and thyroid peroxidase antibodies (TPO-Ab) were quantitatively determined using enzyme linked immuno-assays. Pregnant @entity1 were grouped into three categories (<14 weeks, 14-28 weeks and > 28 weeks). The relationship between pregnancy and @entity1669 was determined using Spearman correlation. Analysis of variance was used in comparison of means, Chi-square test used in analyzing proportions while P  <= 0.05 was considered as significant. RESULTS: The mean age of the pregnant @entity1 was 30.4    6.0 years while the mean gestational age of all pregnant @entity1 was 20.6    9.6 weeks. The mean TPO-Ab of 11.58 IU/ml in the pregnant was significantly higher than that of the controls of 7.23 IU/ml (P < 0.001). Out of 108 pregnant @entity1 , 27 (25%) had elevated TPO-Ab as against about 2% of the nonpregnant @entity1 levels P < 0.001. The number of pregnant @entity1 with elevated TPO-Ab levels decreased from 33.3% in the first group to 25.6% and 15.2% in the second and third groups. CONCLUSION: Thyroid @entity792 expressed by the presence of TPO-Ab is high among pregnant Nigerian @entity1 and the frequency of @entity792 appears to decline with advancing gestational age.

Thyroid XXXX in pregnant Nigerians.

@entity1669 :: ('MESH:D013967', 'Disease') :: ['thyroid autoimmunity'] @entity1 :: ('9606', 'Species') :: ['women'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmunity'] @entity1955 :: ('MESH:D013974', 'Chemical') :: ['thyroxine']
@entity792 :: (MESH:D001327,Disease) :: ['autoimmunity']
