Recent data indicate that in @entity1 with @entity548 ( @entity548 ), low @entity68 levels due to inadequate replacement after hemorrhagic @entity68 losses are associated with elevated factor-VIII plasma levels and consecutively increased risk of @entity1211 . Here, we report a @entity1 with @entity548 , low @entity68 levels, elevated factor-VIII, and recurrent @entity1211 . A 64-year-old multimorbid Serbian gipsy was diagnosed with @entity548 at age 62 years. He had a history of recurrent @entity1415 , teleangiectasias on the lips, @entity8 , and a family history positive for @entity548 . He had experienced recurrent @entity49 ( @entity715 , portal @entity49 , @entity1150 ), insufficiently treated with @entity3924 during 16 months and gastro-intestinal @entity548 . Blood tests revealed sideropenia and elevated plasma levels of @entity2801 . His history was positive for @entity6 , arterial @entity101 , @entity407 , smoking, @entity867 , recurrent @entity385 , recurrent ileus, peripheral @entity455 , @entity305 , mild @entity177 , and @entity302 . Following recent findings, @entity49 was attributed to the sideropenia-induced elevation of @entity2801 . In conclusion, @entity548 may be associated with @entity49 due to elevated factor-VIII associated with low serum @entity68 levels from recurrent @entity548 . @entity68 substitution may prevent @entity548 @entity1 from @entity49 .

XXXX in hereditary hemorrhagic telangiectasia with @entity302 .

@entity1 :: ('9606', 'Species') :: ['patient', 'patients'] @entity2801 :: ('2157', 'Gene') :: ['coagulation factor-VIII'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal and pulmonary arterio-venous malformations'] @entity407 :: ('MESH:D006949', 'Disease') :: ['hyperlipidemia'] @entity455 :: ('MESH:D014652', 'Disease') :: ['arterial occluding disease'] @entity3924 :: ('MESH:D010644', 'Chemical') :: ['phenprocoumon'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hereditary hemorrhagic teleangiectasia', 'bleeding', 'HHT'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1415 :: ('MESH:D004844', 'Disease') :: ['epistaxis'] @entity49 :: ('MESH:D019851', 'Disease') :: ['venous thrombosis', 'hypercoagulability'] @entity305 :: ('MESH:D011115', 'Disease') :: ['polyneuropathy'] @entity1150 :: ('MESH:D020246', 'Disease') :: ['deep venous thrombosis'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal insufficiency'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy'] @entity715 :: ('MESH:D013927', 'Disease') :: ['mesenteric vein thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thrombo-embolism'] @entity867 :: ('MESH:D001922', 'Disease') :: ['cerebral abscess'] @entity68 :: ('MESH:D007501', 'Chemical') :: ['iron', 'Iron'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity49 :: (MESH:D019851,Disease) :: ['Hypercoagulability']
