BACKGROUND: Smoking is well-known as a risk factor for @entity1721 . However, little is known about the effect of this factor on survival. METHODS: @entity418 @entity1 who underwent esophagectomy without any preoperative therapy were retrospectively reviewed. @entity1 ' postoperative overall and disease-free survivals were compared between 2 groups (non-heavy smokers and heavy smokers). RESULTS: A total of 109 cases were evaluated in this study. The 5-year @entity3012 rate of the non-heavy smokers was 53.2% and 32.3% for the heavy group. The 5-year DFS rate of the non-heavy smokers was 51.1% and 27.4% for the heavy group. Kaplan-Meier survival analysis revealed that heavy smokers had significantly poorer @entity3012 (P=0.018) and DFS (P=0.009) than non-heavy smokers. In multivariate analysis, smoking was found to be an independent prognostic factor for @entity3012 (P=0.003; HR: 2.186; 95% CI: 1.309-3.650) and DFS (P=0.001; HR: 2.471; 95% CI: 1.467-4.163). CONCLUSION: Smoking was associated with survival among @entity1 with ESCC, and it was recognized as an independent factor in both @entity3012 and DFS.

Prognostic influence of smoking on XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1721 :: ('MESH:C562729', 'Disease') :: ['esophageal squamous cell carcinoma'] @entity3012 :: ('MESH:C567932', 'Disease') :: ['OS'] @entity418 :: ('MESH:D004938', 'Disease') :: ['Esophageal cancer']
@entity1721 :: (MESH:C562729,Disease) :: ['esophageal squamous cell carcinoma']
