The intermediate and medial hyperstriatum ventrale (IMHV) is a forebrain region in the domestic @entity1573 that is a site of information storage for the learning process of imprinting. We enquired whether imprinting is associated with learning-related increases in @entity460 -dependent, @entity972 -stimulated release of neurotransmitter @entity1522 from the IMHV. Chicks were hatched and reared in darkness until 15-30 h after hatching. They then either remained in darkness or were trained for 2 h by exposure to an imprinting stimulus. One hour later, the chicks were given a preference test and a preference score was calculated from the results of this test, as a measure of imprinting. Chicks were killed 2 h after training. Slices from the left and right IMHV of trained and untrained chicks were superfused with Krebs' solution either with or without @entity460 and the superfusate assayed for @entity369 , @entity492 , @entity7792 , @entity1246 , @entity2227 , @entity2228 and @entity2226 using high-performance liquid chromatography. For @entity460 -containing superfusates from the left IMHV, preference score was significantly correlated with @entity972 -stimulated release of (i) @entity1246 (r=0.51, 23 d.f., P=0.008) and (ii) @entity2226 (r=0.77, 23 d.f., P<0.0001). There was no significant difference between the mean values of trained and untrained chicks for either compound. However, examination of the variance of the data indicated that release of both @entity1246 and @entity2226 increased as a result of learning. No significant correlation between preference score and release was found for any of the @entity1522 from the right IMHV, nor for control tissue from the left IMHV superfused with @entity460 -free solution. These results demonstrate that the learning process of imprinting is associated with increases in releasable pools of @entity1246 and @entity2226 and/or membrane excitability in the left IMHV.

@entity1246 , XXXX and learning: release of @entity1522 from slices of @entity1573 brain following filial imprinting.

@entity7792 :: ('CHEBI:16349', 'Chemical') :: ['citrulline'] @entity2226 :: ('MESH:D013654', 'Chemical') :: ['taurine'] @entity1522 :: ('CHEBI:33709', 'Chemical') :: ['amino acids'] @entity2227 :: ('CHEBI:29987', 'Chemical') :: ['glutamate'] @entity1246 :: ('MESH:D005680', 'Chemical') :: ['GABA'] @entity2228 :: ('CHEBI:57305', 'Chemical') :: ['glycine'] @entity1573 :: ('9031', 'Species') :: ['chick'] @entity492 :: ('CHEBI:29995', 'Chemical') :: ['aspartate'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity369 :: ('CHEBI:29016', 'Chemical') :: ['arginine']
@entity2226 :: (MESH:D013654,Chemical) :: ['taurine']
