BACKGROUND: A prospective, randomized trial was performed to evaluate the long-term outcome and @entity1 satisfaction of laparoscopic complete 360 degrees fundoplication compared with partial posterior 270 degrees fundoplication. Partial fundoplication is purported to have fewer side effects with a higher failure rate in controlling @entity354 ( @entity354 ), while complete fundoplication is thought to result in more @entity1282 and gas-related symptoms. METHODS: @entity1 were randomized to either laparoscopic Nissen (LN) or laparoscopic Toupet (LT) fundoplication. Esophageal manometry, 24-h pH studies, a detailed questionnaire, and a visual analog symptom (VAS) score were completed before and after surgery. A final global outcome questionnaire was performed. Failure was defined as recurrent @entity354 requiring revision surgery, maintenance proton pump inhibitor (PPI) therapy, or surgery for postoperative @entity1282 . RESULTS: One hundred @entity1 were randomized to LN (50) or LT (50). There were no differences between LN and LT with respect to postoperative symptoms and physiological variables except a higher wrap pressure in the LN group (15.2 vs. 12.0 mmHg). Dysmotility improved in 8/14 (57%) and 6/11 (54%) @entity1 in the LN group and the LT group, respectively, after surgery. There was no correlation between @entity4423 and @entity1282 both pre- and post surgery in the two groups. Recurrent symptoms of @entity354 occurred in 8/47 (17.0%) and 8/48 (16.6%) in the LN group and the LT group, respectively. Outcome of @entity1 with @entity4423 was similar to those with normal motility in both groups. At final follow-up (59.76 + or - 24.23 months), in the LN group, 33/37 (89.1%) would recommend surgery to others, 32/37 (86.4%) would have repeat surgery, and 34/37 (91.8%) felt they were better off than before surgery. The corresponding numbers for the LT group (follow-up = 55.18 + or - 25.97 months) were 35/36 (97.2%), 30/36 (83.3%), and 33/36 (91.6%). CONCLUSION: LN and LT are equally effective in restoring the lower esophageal sphincter function and provide similar long-term control of @entity354 with no difference in @entity1282 . @entity4423 had no influence on the outcome of either operation.

Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for XXXX : a prospective, randomized trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity4423 :: ('MESH:D015154', 'Disease') :: ['Esophageal dysmotility', 'dysmotility'] @entity1282 :: ('MESH:D003680', 'Disease') :: ['dysphagia'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux disease', 'GERD']
@entity354 :: (MESH:D005764,Disease) :: ['gastroesophageal reflux disease']
