BACKGROUND: The aim of this study was to compare the clinical profile, outcome and the prevalence and management of @entity417 between two cohorts of renal transplant @entity1 with @entity177 restarting dialysis in 2001 and 2009. METHODS: Cross-sectional, observational, retrospective and multicentre study of 397 @entity1 in the 2001 cohort and 222 in the 2009 cohort. Data were recorded at 0, 3, 6, 9 and 12 months before the onset of dialysis resumption and during the first 90 days after restarting dialysis (mortality and hospital admission). RESULTS: @entity1 in the 2009 cohort were older at the time of inclusion in the study and transplantation, and restarted dialysis therapy with a significantly better glomerular filtration rate. In both cohorts, there was a rapid deterioration of renal function with statistically significant differences in serum @entity1011 and glomerular filtration rate between the monthly intervals -12 and 0. The mean haemoglobin value at -12 months was 11.6 g/dL [7.2 mmol/L] in the 2001 cohort when compared with 12.3 g/dL [7.6 mmol/L] in the 2009 cohort, and at the time of restarting dialysis 9.6 g/dL [6.0 mmol/L] versus 10.6 g/ @entity69747 mmol/L]. The percentage of @entity1 treated with erythropoiesis-stimulating agents, at any time during the 12 months before readmission to dialysis, increased significantly from 61.5% in the 2001 cohort to 96% in the 2009 cohort. There were no significant differences between the 2001 and 2009 cohorts in mortality rate (8.8 versus 9.0%) or hospital admission (31.5 versus 31.1%) during the study time. CONCLUSIONS: At restarting dialysis, the proportion of @entity1 with @entity417 (and its severity) due to progressive graft @entity8 decreased over the past 8 years, increasing significantly the percentage of @entity1 treated with @entity1307 . Differences in morbimortality after dialysis resumption were not observed, this is probably due to an increase in the age of donors and recipients.

Clinical profile and post-transplant XXXX in renal transplant recipients restarting dialysis after a failed graft: changing trends between 2001 and 2009.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['nephropathy'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anaemia'] @entity1307 :: ('2056', 'Gene') :: ['erythropoietin'] @entity177 :: ('MESH:D051437', 'Disease') :: ['graft failure'] @entity69747 :: ('249401', 'Gene') :: ['dL [6.6'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity417 :: (MESH:D000740,Disease) :: ['anaemia']
