AIMS: The aim of the study was to verify in what proportion of @entity1 , device-detected @entity1168 ( @entity1168 ) episodes are indeed @entity943 ( @entity943 ). We investigated also the reasons for inappropriate @entity943 classification and assessed if @entity1 with misdiagnosed @entity943 have distinct characteristics that would help to identify them. METHODS AND RESULTS: The study population consisted of 304 consecutive @entity1 implanted with @entity299 ( @entity299 ) and subsequently monitored via remote monitoring for a median follow-up (FU) of 30.5 months. Intracardiac electrograms of every recorded @entity1168 episode were assessed and classified ( @entity5066 vs. no @entity5066 ) by two experienced cardiologists. During FU, 14 386 episodes of @entity1168 were recorded and classified in 176 (57.9%) @entity1 . In 89.2% of them, these episodes were true @entity5066 (94% @entity955 , 62% de novo). The reasons for @entity1168 misdiagnosis were @entity2194 (89.5%) and noise (10.5%). The mean per cent of day spent in @entity1168 (54.9 vs. 5.86%; P < 0.001) and the occurrence of periods with low CRT pacing (82.8 vs. 55%; P = 0.003) were significantly higher in @entity5066 subjects than in those with misdiagnosed @entity1168 . Episode duration of properly detected AHRs was longer than that of misdiagnosed AHRs. Higher per cent of time spent in @entity1168 was an independent marker of appropriate @entity943 detection [adjusted hazard ratio (HR) 1.04; P = 0.023]. CONCLUSION: Nearly two-thirds of CRT-D @entity1 had @entity1168 episodes within 2.5 years after implantation. Almost 90% of AHRs were indeed @entity5066 . Misdetections were caused by far-field sensing or noise. A two-step diagnostic algorithm (>9% of time spent in AHRs and episode duration >36 s) allowed for proper detection of @entity5066 with a high hit-rate and specificity.

Can we rely on machines? Device-detected atrial high rates correspond well with XXXX in cardiac resynchronization recipients   .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2194 :: ('MESH:D005128', 'Disease') :: ['atrial far-field signals'] @entity5066 :: ('MESH:C566236', 'Disease') :: ['AA'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation'] @entity299 :: ('MESH:D006331', 'Disease') :: ['CRT-Ds', 'cardiac resynchronization therapy defibrillators'] @entity943 :: ('MESH:D001145', 'Disease') :: ['atrial arrhythmias', 'AAs', 'arrhythmias', 'arrhythmia'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['AHR', 'atrial high rate']
@entity943 :: (MESH:D001145,Disease) :: ['atrial arrhythmias']
