BACKGROUND: Treatment of early superficial @entity153 (ESBC) is under debate, and no consensus has been achieved. Different therapeutic methods have been proposed, including surgical resection and endoscopic methods. STUDY OBJECTIVE: To assess the efficacy of cryotherapy in @entity1 with ESBC. @entity1 AND METHODS: @entity1 included in the study had histologically proven ESBC after fiberoptic bronchoscopy. Cryotherapy was performed through a rigid bronchoscope. Efficacy was assessed by endoscopy with multiple biopsies 1 month after treatment and during the follow-up period. Parameters studied were response to treatment, adverse effects, and survival. RESULTS: We included 35 @entity1 (34 @entity1 and 1 @entity1 ). The mean age was 61 +/- 9 years. Multiple locations of ESBC were observed in seven @entity1 (20%). Complete response rate at both 1 month and 1 year was 91% (32 @entity1 ). No severe adverse effects were noted. Local recurrence was observed within 4 years in 10 @entity1 (28%). A follow-up period of at least 4 years was available in 22 @entity1 ; of them, 11 @entity1 (50%) were long-term survivors. CONCLUSION: Our results suggest that cryotherapy is an effective method of treatment in @entity1 with ESBC. Due to its relative tolerance compared to surgery, cryotherapy could be proposed as a first-line therapy in this population with high carcinogenic risk.

Cryotherapy in early superficial XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'woman', 'patients', 'PATIENTS', 'men'] @entity153 :: ('MESH:D002283', 'Disease') :: ['bronchogenic carcinoma']
@entity153 :: (MESH:D002283,Disease) :: ['bronchogenic carcinoma']
