PURPOSE: To evaluate the safety and efficacy of trabeculectomy with or without @entity1138 ( @entity1139 ) in the management of @entity726 in @entity4118 and @entity6781 following congenital @entity231 surgery. @entity1 AND METHODS: All @entity1 of @entity726 with @entity4118 or @entity6781 who underwent trabeculectomy with or without @entity1139 from January 1989 to April 2000 were included. The medical records of 19 consecutive @entity1 (23 eyes) were reviewed. Data collected from a retrospective chart review were analysed. Outcome measures were evaluated using Kaplan-Meier survival analysis. Pre- and postoperative intraocular pressures (IOPs), visual acuities, success rate, @entity4530 characteristics, surgical failure and complications were the main outcome measures. Successful IOP control was defined as an IOP between 6 and 21 mmHg, without antiglaucoma medications, without further antiglaucoma surgery and without any sight-threatening complication. RESULTS: The mean age of @entity1 was 8.8+/-5.5 years at the time of trabeculectomy with @entity1139 compared to 11.0+/-12.4 years for trabeculectomy without @entity1139 . Eight @entity1 underwent trabeculectomy with @entity1139 and 11 @entity1 underwent trabeculectomy without @entity1139 . There was no statistically significant difference between the two groups in terms of visual acuity, IOP, antiglaucoma medications, age at @entity231 surgery and at trabeculectomy. The IOP reduced from a preoperative level of 34.2+/-8.9 mmHg (range: 20-52) to a postoperative level of 18.4+/-12.2 mmHg (range: 2-60) with a mean follow-up of 24.2+/-17.9 months. The mean reduction in IOP in the @entity1139 group was 15.5+/-17.3 and 16.3+/-13.8 mmHg in the other group (P = 0.967). Overall, complete success was achieved in 36.8%, qualified success in 21.1% and surgical failure in 42.1% of @entity1 with a mean follow-up of 24.2+/-17.9 months. There was no difference in the success between the two groups at the last follow-up. One @entity1 developed @entity4530 -related @entity735 following trabeculectomy with @entity1139 . CONCLUSIONS: The success rate of trabeculectomy in @entity726 following congenital @entity231 surgery was 36.8% at the end of 3 years. The present study proves a poor success rate of trabeculectomy in a small series of aphakic Asian Indian @entity1 even with the use of @entity1139 .

Trabeculectomy with or without @entity1138 for paediatric @entity726 in @entity4118 and XXXX following congenital @entity231 surgery.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity6781 :: ('MESH:D019591', 'Disease') :: ['pseudophakia'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract'] @entity4530 :: ('MESH:D001768', 'Disease') :: ['bleb'] @entity4118 :: ('MESH:D001035', 'Disease') :: ['aphakia'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin-C'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity1139 :: ('CHEBI:27504', 'Chemical') :: ['MMC'] @entity735 :: ('MESH:D005124', 'Disease') :: ['endophthalmitis in both eyes']
@entity6781 :: (MESH:D019591,Disease) :: ['pseudophakia']
