UNASSIGNED: OBJECT @entity976 are associated with a high rate of recurrence. The surgical management of recurrent lesions has been among the most challenging neurosurgical procedures because of the @entity976 's complex topographical relationship with surrounding structures. The aim of this study was to define the determinative role of the site of origin on the growth pattern and clinical features of recurrent @entity976 . METHODS The authors performed a retrospective analysis of 52 @entity1 who had undergone uniform treatment by a single surgeon. For each @entity1 , data concerning symptoms and signs, imaging features, @entity2339 , and recurrence-free survival rate were collected. RESULTS For @entity1 , delayed @entity1175 was more frequent in the group with Type I (infradiaphragmatic) @entity976 than in the group with Type @entity1804 ( @entity1804 ) lesions (p < 0.05). For adults, @entity1939 was more frequent in the Type I group than in the Type @entity1804 group (p < 0.05). @entity390 or @entity391 , delayed @entity1175 , and @entity851 were more frequent in @entity1 than in adults (p < 0.05). Overall clinical outcome was good in 48.07% of the @entity1 and poor in 51.92%. @entity1 with @entity5 had significantly worse functional outcomes and hypothalamic function than @entity1 with the @entity5 but better pituitary function especially in @entity1 . CONCLUSIONS The origin of recurrent @entity976 significantly affected the symptoms, signs, functional outcomes, and hypothalamic-pituitary functions of @entity1 undergoing repeated surgery. Differences in @entity5 growth patterns and site of origin should be considered when one is comparing outcomes and survival across treatment paradigms in @entity1 with recurrent @entity976 .

Origin of @entity976 : implications for growth pattern, clinical characteristics, and outcomes of XXXX recurrence.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'patient'] @entity851 :: ('MESH:D006130', 'Disease') :: ['growth retardation'] @entity390 :: ('MESH:D009325', 'Disease') :: ['Nausea'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Type TS recurrent tumors', 'Type I recurrent tumors', 'tumor'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity1804 :: ('MESH:D020863', 'Disease') :: ['TS', 'tuberoinfundibular and suprasellar extraventricular'] @entity1175 :: ('MESH:D011628', 'Disease') :: ['puberty'] @entity1939 :: ('MESH:D001766', 'Disease') :: ['blindness'] @entity2339 :: ('MESH:D007029', 'Disease') :: ['hypothalamic-pituitary function'] @entity976 :: ('MESH:D003397', 'Disease') :: ['craniopharyngiomas', 'craniopharyngioma', 'Craniopharyngiomas']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
