@entity3657 ( @entity3657 ) is a common complication of @entity6 ( @entity6 ) and often culminates in amputation of the affected foot. @entity796 @entity281 associated with @entity3657 are difficult to treat due to their multi-drug resistance. Herein we report a 38 year old male who reported with @entity6 , @entity740 ( @entity740 ) and @entity158 of the right second toe in October 2011. He underwent percutaneous transluminal angioplasty (PTA) which was unsuccessful. The gangrene of the toes worsened and amputation of the right second toe was done. Bacteriological examination showed presence of @entity796 which during the course of antibiotic therapy became multi-drug resistant. Gangrene and abscess of the foot worsened and amputation of the right third toe was performed. Then autologous peripheral blood mononuclear cell (PBMNC) therapy was performed but as @entity281 control could not still be achieved, the fourth toe was amputated. A protocol of foot bath using carbonic water, local usage of antibiotics ( @entity6414 ), and @entity540 ( @entity540 ) spray was then employed after which the @entity281 could be controlled and improvement in vascularity of the right foot could be observed in angiography. This combined approach after proper validation could be considered for similar cases.

Combining autologous peripheral blood mononuclear cells with fibroblast growth factor therapy along with stringent XXXX control leading to successful limb salvage in @entity6 patient with chronic renal failure and severe toe gangrene.

@entity796 :: ('287', 'Species') :: ['Pseudomonas aeruginosa', 'P. aeruginosa'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes Mellitus', 'DM'] @entity3657 :: ('MESH:D058729', 'Disease') :: ['Peripheral arterial disease', 'PAD'] @entity6414 :: ('MESH:D011112', 'Chemical') :: ['Polymyxin-B'] @entity740 :: ('MESH:D051436', 'Disease') :: ['CKD', 'chronic kidney disease'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'infections'] @entity540 :: ('2247', 'Gene') :: ['b-FGF', 'basic fibroblast growth factor'] @entity158 :: ('MESH:D010146', 'Disease') :: ['rest pain']
@entity281 :: (MESH:D007239,Disease) :: ['infection']
