OBJECTIVE: @entity933 is a common syndrome in older @entity1 after surgery. Although an @entity3202 change in the whole brain may be a potential risk factor for @entity260 , the anatomically specific change related to the vulnerability still remains a significant issue. DESIGN: Prospective study. SETTING: University hospital. @entity1 : 116 consecutive @entity1 who underwent elective cardiac operations. MEASUREMENTS: Before the surgery, magnetic resonance imaging (MRI) was evaluated. The MRI data were processed to calculate the absolute volumes of the predefined region of interest using Statistical Parametrical Mapping 8 with an atlas-based method. The evaluated volume was expressed as the fraction (%) of the total intracranial volume. @entity260 was diagnosed according to the DSM-IV criteria for @entity933 . RESULTS: @entity933 developed in 19 of 116 @entity1 (16.4%) with an age range from 58 to 84 years. Based on a comparison with the age-controlled non- @entity933 @entity1 (over 57 years; n   =   65), a statistically significant reduction in the gray matter volume of the @entity933 @entity1 was observed in the defined gyri of the temporal and limbic lobes. Moreover, a moderate value (>0.8) of area under the curve to predict @entity260 was revealed by receiver operating characteristic curve analysis of the gyri of temporal lobe. CONCLUSIONS: The decreased volume of gray matter could be associated with the vulnerability to @entity933 after surgery. The atlas-based method would be a potential tool to pre-screen the brain structure of individual @entity1 for the prediction of @entity260 .

A Decrease in the Volume of Gray Matter as a Risk Factor for XXXX Revealed by an Atlas-based Method.

@entity933 :: ('MESH:D003693', 'Disease') :: ['delirium', 'Delirium'] @entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative delirium', 'Postoperative delirium'] @entity3202 :: ('MESH:D016109', 'Disease') :: ['atrophic']
@entity260 :: (MESH:D011183,Disease) :: ['Postoperative Delirium']
