BACKGROUND: Cerebral protection during surgery for @entity697 relies on hypothermic @entity1167 , either alone or in conjunction with cerebral perfusion. METHODS AND RESULTS: The perioperative and intraoperative conditions of 1558 @entity1 submitted from 44 cardiac surgery centers in German-speaking countries were analyzed. Among @entity1 with @entity697 , 355 (22.8%) underwent surgery with hypothermic @entity1167 alone. In 1115 @entity1 (71.6%), cerebral perfusion was used: Unilateral @entity1779 ( @entity1779 ) in 628 (40.3%), bilateral @entity1779 in 453 (29.1%), and retrograde perfusion in 34 @entity1 (2.2%). For 88 @entity1 with @entity697 (5.6%), no @entity1167 and arch intervention were reported (cardiopulmonary bypass-only group). End points of the study were 30-day mortality (15.9% overall) and mortality-corrected permanent @entity51 (10.5% overall). The respective values for the cardiopulmonary bypass-only group were 11.4% and 9.1%. Hypothermic @entity1167 alone resulted in a 30-day mortality rate of 19.4% and a mortality-corrected permanent @entity51 rate of 11.5%, whereas the rates were 13.9% and 10.0%, respectively, for unilateral @entity1779 and 15.9% and 11.0%, respectively, for bilateral @entity1779 . In contrast with the @entity1779 groups, there was a profound increase in mortality when systemic @entity1167 times exceeded 30 minutes in the hypothermic @entity1167 group (P<0.001). Mortality-corrected permanent @entity51 correlated significantly with perfusion pressure in the @entity1779 groups. CONCLUSIONS: This study reflects current surgical practice for @entity697 in Central Europe. For arrest times less than 30 minutes, hypothermic @entity1167 and @entity1779 lead to similar results. For longer arrest periods, @entity1779 with sufficient pressure is advisable. Outcomes with unilateral and bilateral @entity1779 were equivalent.

Cerebral protection during surgery for XXXX : results of the German Registry for Acute Aortic Dissection Type A (GERAADA).

@entity1 :: ('9606', 'Species') :: ['patients'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute aortic dissection type A'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological dysfunction'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['circulatory arrest'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['ACP', 'antegrade cerebral perfusion']
@entity697 :: (MESH:D000208,Disease) :: ['acute aortic dissection type A']
