PURPOSE: Health-related quality of life (HRQOL) is a critical @entity6 outcome, yet differences between youth and parent-proxy ratings can make interpretation difficult. This study aims to explore potential differences between self- and parent-reports of Pediatric Quality of Life Inventory (PedsQL) scores from youth with type 1 (T1D) or @entity2175 ( @entity2175 ) and to evaluate associations between discrepancies, PedsQL scores, and glycemic control (HbA1c). METHODS: Youth and parents in the SEARCH for @entity6 in Youth Study (T1D: age 5-18, n  =  3402; @entity2175 : age 8-18, n  =  353) completed the PedsQL Generic and @entity6 Modules, and youth provided a blood sample to assess HbA1c. Discrepancies (youth minus parent PedsQL ratings) were calculated and examined by age and @entity6 , and associations with youth PedsQL scores and HbA1c were evaluated. RESULTS: Discrepancies existed between youth and parent-proxy reports of generic and @entity6 PedsQL scores in T1D and @entity2175 (all p values  <  0.01). Higher (more favorable) ratings were reported by youth except for those 5-7-years old, where parents' scores were higher. When parent-proxy scores were higher, discrepancies were largest when the @entity1 reported low PedsQL scores. Higher HbA1c was associated with larger discrepancies (youth scores higher) for adolescents with T1D. CONCLUSIONS: Discrepant PedsQL ratings suggest that parents may often underestimate youths' HRQOL except in the youngest @entity1 . Although examining both reports is optimal, the youth report should be prioritized, particularly for young @entity1 with T1D and for adolescents with either @entity2175 .

Whose quality of life is it anyway? Discrepancies between youth and parent health-related quality of life ratings in type 1 and XXXX .

@entity2175 :: ('MESH:D003924', 'Disease') :: ['type 2 diabetes', 'T2D', 'T1D or T2D'] @entity1 :: ('9606', 'Species') :: ['children', 'child'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetes type', 'diabetes']
@entity2175 :: (MESH:D003924,Disease) :: ['type 2 diabetes']
