BACKGROUND: To investigate @entity86 ( @entity86 ) prevention by @entity3477 prophylaxis. METHODS: After crystalline lens removal and @entity2790 ( @entity2790 ) implantation, 18 @entity95 eyes were injected intracameral with different coagulase negative staphylococci (CNS) inoculums in order to determine the minimum inoculum required for a reproducible @entity86 model. Another 28 similar eyes were divided into Group A, which was implanted with standard IOLs with intracameral injection of 100  g/0.1 ml @entity3477 , Group B implanted with @entity3477 presoaked IOLs, Group C treated as Groups A and B, and Group D (control) implanted with standard IOLs only. At the end of surgery, all eyes were injected with the minimal inoculum that had developed @entity86 , and treated with topical @entity3477 for 24 hours. They were then evaluated using 3 different @entity86 scores. RESULTS: The minimum CNS concentration that developed reproducible @entity86 was 5x10(5) CFUs/0.1 ml. Scores: 1. Clinical @entity3225 was judged in 5/7 (71%), 4/7 (57%), 2/7 (28%) and 7/7 (100%) of Groups A-D eyes, respectively, p=0.005 and 0.057 for Groups B and C compared to D, respectively. 2. @entity3225 Scores for Groups A-D were 14.5  6.8, 10.6  4.5, 12.0  3.9 and 18.6  1.7, respectively, p=0.015, and ~0.07 for Groups B and C compared to D, respectively. 3. Hypoyon was noted in 2/6 (33%), 2/7 (28%), 2/7 and 6/7 (86%) of the Group A-D eyes, respectively, p=0.053, 0.03 and 0.03 for Groups A-C compared to D, respectively. CONCLUSION: @entity86 can be best prevented by prophylactic @entity3477 by presoaked IOLs treatment.

Prevention of Staphylococcus EpidermidisEndophthalmitis by Different XXXX Prophylaxis Routes.

@entity3477 :: ('MESH:C104727', 'Chemical') :: ['moxifloxacin'] @entity95 :: ('9986', 'Species') :: ['rabbit'] @entity2790 :: ('MESH:D009798', 'Disease') :: ['IOL', 'intraocular lens'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative endophthalmitis', 'POE'] @entity3225 :: ('MESH:D009877', 'Disease') :: ['endophthalmitis', 'Endophthalmitis']
@entity3477 :: (MESH:C104727,Chemical) :: ['Moxifloxacin']
