@entity39 soft-tissue infections are usually polymicrobial, with greater than 90 per cent involving beta-hemolytic streptococci or coagulase-positive staphylococci. The remaining 10 per cent are usually due to Gram-negative enteric pathogens. We describe the case of a 46-year-old @entity1 with bilateral @entity9244 . She underwent multiple surgical debridements of extensive @entity39 of the skin and subcutaneous fat associated with severe acute @entity3468 . Histopathological examination revealed @entity11150 as the sole initial pathogen. Despite aggressive surgical debridement, allografts, and intravenous @entity2379 , her condition clinically deteriorated and she ultimately died of overwhelming infection. Treatment for soft-tissue infections include surgical debridement and intravenous antibiotics. More specifically, @entity11150 can be treated with intravenous @entity2379 , @entity4895 , and @entity1215 . Despite these treatment modalities, necrotizing @entity9156 is associated with a 60 per cent mortality rate. Primary fungal pathogens should be included in the differential diagnosis of soft-tissue infections.

XXXX : a rare primary organism in soft-tissue infections.

@entity1 :: ('9606', 'Species') :: ['woman'] @entity2379 :: ('MESH:D000666', 'Chemical') :: ['amphotericin B'] @entity39 :: ('MESH:D009336', 'Disease') :: ['Nonclostridial necrotizing', 'gangrenous necrosis'] @entity11150 :: ('5061', 'Species') :: ['Aspergillus niger', 'Aspergillus'] @entity4895 :: ('MESH:D005437', 'Chemical') :: ['5-fluorocytosine'] @entity3468 :: ('MESH:D001167', 'Disease') :: ['arteritis'] @entity1215 :: ('MESH:D012293', 'Chemical') :: ['rifampin'] @entity9244 :: ('MESH:D018461', 'Disease') :: ['lower extremity fungal soft tissue infections'] @entity9156 :: ('MESH:D005208', 'Disease') :: ['fascitis']
@entity11150 :: (5061,Species) :: ['Aspergillus']
