A defined agar medium (A agar) containing 15 @entity1522 in concentrations between 0.5 and 2 mm was developed for studying the fruiting cycle of @entity4986 FBa. Cells grew only vegetatively in this medium unless the initial concentration of one of nine required or stimulatory @entity1522 was lowered about 50-fold. In the latter circumstance, fruiting bodies developed after several days of vegetative growth. The conclusion was that fruiting occurred when any @entity535 required for normal growth became limiting in the environment. High concentrations (10 mm) of @entity815 , @entity2340 , or @entity1853 prevented fruiting without affecting growth. Mutants requiring @entity369 , @entity1014 , or @entity5536 could not be induced to fruit by limiting their unique requirement although they responded to the same deprivations which brought about fruiting of the wild type. A @entity3793 auxotroph formed fruiting bodies when @entity3793 was lowered to growth-limiting concentrations, provided that the medium was supplemented with purines. A @entity5537 auxotroph was isolated that, perhaps secondarily, had lost some of the mechanisms which control the formation of fruiting bodies; if @entity5537 was present, it formed fruits even when no @entity535 was limiting. No concentration of @entity5537 was sufficient to prevent fruiting. Fruiting bodies were formed when mixtures of the @entity5537 auxotroph and wild-type cells were inoculated on A agar plus @entity5537 , even when 75% of the cells were wild type. Microcysts of both strains were present in the fruiting bodies.

Nutritional induction and suppression of fruiting in XXXX FBa.

@entity1522 :: ('CHEBI:33709', 'Chemical') :: ['amino acids'] @entity535 :: ('CHEBI:33704', 'Chemical') :: ['amino acid'] @entity3793 :: ('CHEBI:27570', 'Chemical') :: ['histidine'] @entity1853 :: ('MESH:D008715', 'Chemical') :: ['methionine'] @entity4986 :: ('34', 'Species') :: ['Myxococcus xanthus'] @entity2340 :: ('CHEBI:27897', 'Chemical') :: ['tryptophan'] @entity5536 :: ('MESH:D000225', 'Chemical') :: ['adenine'] @entity1014 :: ('MESH:D013936', 'Chemical') :: ['thymidine'] @entity815 :: ('CHEBI:28044', 'Chemical') :: ['phenylalanine'] @entity5537 :: ('MESH:D014498', 'Chemical') :: ['uracil'] @entity369 :: ('CHEBI:29016', 'Chemical') :: ['arginine']
@entity4986 :: (34,Species) :: ['Myxococcus xanthus']
