INTRODUCTION: Meeting enteral nutrition goals is an ongoing challenge in the intensive care unit (ICU). Most hospitals use @entity1168 ( @entity1168 ) protocols for nutrient delivery. Previous studies have found that @entity1297 ( @entity1297 ) protocols improve delivery of prescribed calories. However, these studies did not assess clinical outcomes. We hypothesize that a @entity1297 method will improve the delivery of prescribed calories and lead to improved clinical outcomes. METHODS: A before-and-after study was performed following implementation of a @entity1297 feeding protocol in an adult mixed medical-surgical ICU. Formal institutional review board approval was obtained. The effect of @entity1168 and @entity1297 protocols on percentage of goal calories received, ICU length of stay (LOS), hospital LOS, mortality, days on the ventilator, and rates of @entity281 were investigated using the Kruskal-Wallis test of differences. Multivariate regression was used to identify independent predictors of outcome. Significance was defined as P < .05. RESULTS: A total of 77 @entity1 were included ( @entity1168 = 39, @entity1297 = 38). There were no differences in demographics between the 2 groups with the exception of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score, which was significantly higher in the @entity1297 group. @entity1297 @entity1 received significantly more prescribed calories (74% vs 57%, P < .001). @entity1297 @entity1 had significantly longer ICU LOS and duration of mechanical ventilation on univariate analysis. These differences did not persist after controlling for APACHE II score. CONCLUSION: @entity1297 enteral feeding allows for a significantly greater provision of prescribed calories but may not affect clinical outcomes. A larger sample size is needed for adequate power to corroborate these findings.

A Volume-Based Enteral Nutrition Support Regimen Improves Caloric Delivery but May Not Affect Clinical Outcomes in Critically Ill XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['rate-based', 'RB'] @entity1297 :: ('MESH:D019292', 'Disease') :: ['VB', 'volume-based']
@entity1 :: (9606,Species) :: ['Patients']
