OBJECTIVE: To correlate @entity79 ( @entity79 ) in @entity1 with primary hypoestrogenism caused by 46,XX pure @entity444 or @entity2689 with age, age at @entity172 therapy initiation, length of @entity172 use, and body mass index (BMI). DESIGN: Cross-sectional study. SETTING: Academic tertiary-care hospital. @entity1 (S): Thirty-eight @entity1 , aged 16 to 35 years (mean, 24.6 years), affected by these @entity74 . INTERVENTION(S): Measurement of lumbar spine and femoral neck @entity79 using double x-ray absorptiometry. The results were correlated with the control variables by using Pearson's coefficient of correlation. Variables associated with @entity79 were evaluated by multiple linear regression analysis. MAIN OUTCOME MEASURE(S): Bone mineral density. RESULT(S): Bone mineral density of the lumbar spine showed that 90% of the @entity1 presented @entity2331 or @entity170 . The femoral neck was affected in 55% of these @entity1 . The length of @entity172 therapy and the BMI showed a positive association with @entity79 at the lumbar spine and femoral neck, respectively. CONCLUSION(S): @entity1 affected by pure @entity444 or @entity2689 presented a marked decrease in @entity79 of the lumbar spine and femoral neck. Medical attention for their diagnosis and early hormone replacement therapy are advised.

Factors associated with the reduction of bone density in XXXX with @entity444 .

@entity1 :: ('9606', 'Species') :: ['women', 'Women', 'PATIENT'] @entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity170 :: ('MESH:D010024', 'Disease') :: ['osteoporosis'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity2331 :: ('MESH:D001851', 'Disease') :: ['osteopenia'] @entity2689 :: ('MESH:D014424', 'Disease') :: ["Turner's syndrome"] @entity74 :: ('MESH:D030342', 'Disease') :: ['genetic disorders'] @entity444 :: ('MESH:D006059', 'Disease') :: ['gonadal dysgenesis']
@entity1 :: (9606,Species) :: ['patients']
