BACKGROUND: Without specific symptoms, diagnosis of @entity221 in returning travelers is challenging. @entity779 , @entity311 , and @entity221 are common causes of @entity221 in returning travelers and timely and appropriate treatment is important. However, differentiation is difficult without specific diagnostic tests. METHODS: A retrospective study was conducted at the National Centre for Global Health and Medicine (NCGM) from April 2005 to March 2013. Febrile travelers returning from overseas who were diagnosed with @entity779 , @entity311 , or @entity221 were included in this study. Clinical characteristics and laboratory findings were compared for each diagnosis. RESULTS: During the study period, 86 @entity311 , 85 @entity779 , and 31 @entity221 were identified. The mean age of the study cohort was 33.1    12 years and 134 (66.3%) study @entity1 were male. Asia was the most common area visited by returning travelers with fevers (89% of @entity779 , 18.6% of @entity311 , and 100% of @entity221 ), followed by Africa (1.2% of @entity779 and 70.9% of @entity311 cases). Clinical characteristics and laboratory findings were significantly different among each group with each diagnosis. Decision tree models revealed that returning from Africa and CRP levels < 10 mg/L were factors specific for diagnosis of @entity311 and @entity779 , respectively. CONCLUSION: Clinical manifestations, simple laboratory test results, and regions of travel are helpful to distinguish between @entity779 , @entity311 , and @entity221 in febrile returning travelers with non-specific symptoms.

Comparison of clinical characteristics and laboratory findings of XXXX , @entity779 in returning travelers: 8-year experience at a referral center in Tokyo, Japan.

@entity1 :: ('9606', 'Species') :: ['participants'] @entity311 :: ('MESH:D008288', 'Disease') :: ['malaria'] @entity779 :: ('MESH:D003715', 'Disease') :: ['dengue', 'Dengue', 'dengue fever'] @entity221 :: ('MESH:D005334', 'Disease') :: ['enteric fever', 'enteric fever cases', 'febrile illness', 'fever']
@entity311 :: (MESH:D008288,Disease) :: ['malaria']
