BACKGROUND: Scoliosis fusion surgery is generally considered the only means to stop the progression of @entity2112 ( @entity2112 ), but for @entity1 refusing surgery there is lack of evidence in favour of conservative treatment. The aim of the present study was to verify the possible effectiveness of @entity1635 -specific exercises when facing @entity2112 progression. METHODS: We designed a retrospective cohort study. We included 34 @entity2112 @entity1 in treatment at our Institute (5 males and 29 females, mean age was 38.0        11.0), exclusively treated with specific Scoliosis Specific SEAS exercises. INSTRUMENTATION: SEAS exercises are @entity1635 -specific exercises. In adult @entity1 they are aimed to recover postural collapse, postural control and vertebral stability through an active self-correction. Postural integration is a key element, including the neuromotor integration of correct postures and an ergonomic education program. Therapy includes at least two weekly exercise sessions each lasting 45  min. OUTCOME MEASURES: Radiographic progression was the main outcome and it was analysed as a continuous variable. STATISTICS: One way ANOVA and paired t-test were applied for continuous data, while chi-square test was applied for categorical data. Alpha was set at 0.05. RESULTS: The mean Cobb angle of the @entity1 included into the present study, was 55.8        13.2     . Fifteen @entity1 had previous x-rays testifying @entity1635 progression: the average curve progression (worsening) was 9.8        6.6      at a median of 25 (range 17-48) years. The remaining were characterized by more severe curves, exceeding 40      Cobb (mean curvature 50.9        13.6) but it was not possible to prove that the curves had progressed in these cases. After an average period of 2  years of treatment (range 1-18y), 68  % of the @entity1 experienced an improvement in their @entity1635 . However in one @entity1 (3  %) the @entity1635 worsened by 5      in 18  years (progression rate reduced from 0.5      to 0.27      per year). @entity1 improved 4.6        5.0      Cobb (P   <   0.05), with no differences based on the localization of the curve, gender, age, length of treatment, Cobb degrees at the start of observation or treatment. CONCLUSIONS: Scoliosis Specific SEAS Exercises proved to be superior to natural history in @entity2112 , at least in individual cases and should be considered as a first line treatment especially in @entity1 refusing @entity1635 surgery.

Scoliosis-Specific exercises can reduce the progression of severe curves in XXXX : a long-term cohort study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity2112 :: ('MESH:C564593', 'Disease') :: ['adult idiopathic scoliosis', 'ADIS'] @entity1635 :: ('MESH:D012600', 'Disease') :: ['scoliosis']
@entity2112 :: (MESH:C564593,Disease) :: ['adult idiopathic scoliosis']
