OBJECTIVES: To estimate the relative risk of @entity301 ( @entity301 ) associated with exposure to environmental @entity286 smoke (ETS). DESIGN: Population-based case-control study. SUBJECTS: Cases were 953 @entity1 identified in a population register of coronary events, and controls were 3189 @entity1 in independent community-based risk factor prevalence surveys from the same study populations. SETTING: Newcastle, Australia and Auckland, New Zealand. MAIN OUTCOME MEASURES: Acute @entity583 or @entity204 . RESULTS: After adjusting for the effects of age, education, history of @entity299 , and body mass index, @entity1 had a statistically significant increased risk of a coronary event associated with exposure to ETS (relative risk (RR) = 1.99; 95% confidence interval (CI) = 1.40-2.81). There was little statistical evidence of increased risk found in @entity1 (RR = 1.02, 95% CI = 0.81-1.28). CONCLUSION: Our study found evidence for the adverse effects of exposure to ETS on risk of @entity301 among @entity1 , especially at home. For @entity1 the issue is unclear according to the data from our study. Additional studies with detailed information on possible confounders and adequate statistical power are needed. Most importantly, they should use methods for measuring exposure to ETS that are sufficiently accurate to permit the investigation of dose-response relationships.

Coronary events and exposure to environmental XXXX smoke: a case-control study from Australia and New Zealand.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'people', 'men'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity301 :: ('MESH:D003327', 'Disease') :: ['CHD', 'coronary heart disease'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart disease'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['coronary death']
@entity286 :: (4097,Species) :: ['tobacco']
