OBJECTIVE: To describe contemporary outcomes of @entity2333 ( @entity2333 ) performed in 22 US centers. BACKGROUND: @entity2333 constitutes first-line therapy for @entity472 ( @entity472 ) in many centers. METHODS: We used prospectively-collected data from two active, multi-institutional, pediatric cardiac catheterization registries. Acute procedural success was defined, for purposes of this review, as a residual peak systolic gradient    <=   35 mm Hg and no more than mild @entity337 ( @entity337 ) for @entity1 with isolated @entity472 . For @entity1 with mixed @entity886 , a residual peak systolic gradient    <=   35 mm Hg without worsening of @entity337 was considered successful outcome. RESULTS: In 373 @entity1 with a median age of 8 months (1 day to 40 years of age) peak systolic gradient had a median of 59 [50, 71] mm Hg pre- @entity2333 and 22 [15, 30] mm Hg post- @entity2333 (P   <   0.001). Procedural success was achieved in 160 @entity1 (71%). The factors independently associated with procedural success were: first time intervention (OR   =   2.0 (1.0, 4.0) P   =   0.04), not- @entity3009 dependent, (OR=3.5 (1.5, 8.1); P   =   0.003), and isolated @entity472 (absence of @entity337 ) (OR   =   2.1 (1.1-3.9); P   =   0.03). Twenty percent of @entity1 experienced adverse events, half of which were of high severity. There was no procedural mortality. Neonatal status was the only factor associated with increased risk of high severity adverse events (OR 3.7; 95% CI 1.5-9.0). CONCLUSION: In the current era, @entity2333 results in procedural success (gradient reduction with minimal increase in @entity337 ) in 71% of @entity1 treated at US centers where @entity2333 is considered first-line therapy relative to surgery.    2015 Wiley Periodicals, Inc.

Balloon valvuloplasty for XXXX : Multi-center safety and efficacy outcome assessment.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity886 :: ('MESH:C563178', 'Disease') :: ['aortic valve disease'] @entity3009 :: ('CHEBI:26333', 'Chemical') :: ['prostaglandin'] @entity337 :: ('MESH:D001022', 'Disease') :: ['AR', 'aortic regurgitation'] @entity2333 :: ('MESH:D001018', 'Disease') :: ['BAVP', 'balloon aortic valvuloplasty'] @entity472 :: ('MESH:D001024', 'Disease') :: ['congenital aortic stenosis', 'cAS']
@entity472 :: (MESH:D001024,Disease) :: ['congenital aortic stenosis']
