AIMS: Adipocyte and epidermal @entity844 -binding protein ( @entity5548 , @entity21034 ) are cytoplasmic proteins which may play an important role in @entity209 . In the present study, we investigated the different association of @entity5548 and @entity21034 with @entity209 ( @entity209 ) and @entity453 ( @entity453 ) in Chinese adults. METHODS: A total of 459 subjects (233 @entity209 and 226 non- @entity209 ) who had undergone coronary angiography were enrolled in the present study. Serum @entity5548 and @entity21034 levels, @entity413 , lipid profiles and other biochemical markers were measured. RESULTS: Both serum @entity5548 and @entity21034 levels were significantly higher in the @entity209 group than in the non- @entity209 group (P = 0.040 and 0.045, respectively). Only serum @entity5548 levels in the @entity453 group were significantly higher than in the non- @entity453 group (12.30    5.45 vs.10.94    4.94 ng/mL, P= 0.008), and significantly increased with the increasing of number of disease vessels (P=0.004). Serum @entity5548 levels were also associated with risk of @entity453 (odds ratio 2.956 [1.295-6.748]; P = 0.010). Adjusting for age, sex, and other conventional risk factors for @entity453 did not appreciably change the results. No difference was found in serum @entity21034 levels between @entity453 status. Serum @entity21034 levels were correlated with fasting and post load 2h plasma @entity413 , HbA1c, serum total @entity165 and LDL-C concentrations while serum @entity5548 levels were correlated with fasting and post load 2h serum insulin concentrations and HOMA-IR (different P<0.05). CONCLUSIONS: Our data indicated while both serum @entity5548 and @entity21034 levels had associations with @entity209 , only @entity5548 was significantly associated with increased risk of @entity453 in Chinese adults.

Different association of circulating levels of adipocyte and epidermal @entity844 -binding proteins with @entity209 and XXXX in Chinese adults.

@entity844 :: ('CHEBI:35366', 'Chemical') :: ['fatty acid'] @entity5548 :: ('2167', 'Gene') :: ['A-FABP'] @entity21034 :: ('2171', 'Gene') :: ['E-FABP'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic diseases', 'metabolic syndrome', 'MetS'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'coronary artery disease'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity453 :: (MESH:D003324,Disease) :: ['coronary atherosclerosis']
