OBJECTIVES: To determine the frequency of the use of proton-pump inhibitor therapy in @entity1 with typical symptoms of @entity354 and evaluate its risk factors. METHODS: The cross-sectional study was conducted between June 2010 and February 2011 across 10 cities of Pakistan. Adult @entity1 giving a current history of typical @entity354 were included. Information on @entity1 demography, medical history, family history, prescription patterns, lifestyle factors and dietary habits were collected. SPSS 18 was used for statistical analysis and descriptive statistics were used for the analysis of categorical and continuous variables. RESULTS: Of the 1010 @entity1 enrolled, 954 (94.45%) formed the study population. Of them, 520 (54.5%) were @entity1 . The overall mean age was 41.9 +/- 12.5 years, and 439 (46%) had body mass index > or = 25 kg/m2. Further, 805 (84.4%) reported history of @entity2210 while 692 (72.5%) had @entity354 during the preceding year. Family history of acid peptic disease was reported by 231 (24.2%) @entity1 . Prior to consultation, 505 (52.9%) @entity1 were on proton-pump inhibitors. Following consultation, 923 (96.8%) @entity1 were prescribed proton-pump inhibitors, with @entity4546 being the preferred choice in 577 (60.5%). Associated risk factors included regular use of nonsteroidal anti-inflammatory drugs in 355 (37.2%) and current smoking in 210 (22.0%). Consuming spicy meals was reported by 666 (70.0%). CONCLUSION: Nearly half the @entity1 with typical @entity354 were overweight, and a majority consumed spicy meals. Proton-pump inhibitors were widely prescribed, and @entity4546 was the preferred choice of drug.

Risk factors and prescription patterns of XXXX : HEAL study in Pakistan.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'men'] @entity2210 :: ('MESH:D004415', 'Disease') :: ['dyspepsia'] @entity4546 :: ('MESH:D009853', 'Chemical') :: ['omeprazole'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux disease', 'gastroesophageal reflux disease symptoms']
@entity354 :: (MESH:D005764,Disease) :: ['gastroesophageal reflux disease']
