BACKGROUND AND PURPOSE: Impairment of the cerebral autoregulation is an important predictor of @entity4905 and @entity64 in @entity1 with an @entity850 . The autoregulative status can be assessed directly by measuring the vasodilatory capacity of the cerebral arteries. The aim of our study was to investigate the vasodilatory capacity of the proximal and distal cerebral vasculature in @entity1 with an @entity850 and healthy control subjects by combining MRA with an @entity3791 provocation challenge. MATERIALS AND METHODS: Fourteen functionally independent @entity1 (mean age, 67.2    8.7 years) with a @entity850 and 19 healthy controls (mean age, 63.1    7.2 years) were included. MRA was performed before and 20 minutes after intravenous administration of @entity3791 . The vasodilatory capacity of 11 proximal and distal cerebral vessels was assessed by measuring the increase in vessel diameter after @entity3791 . RESULTS: In the hemisphere @entity850 , there was no increase in diameter after @entity3791 , whereas a significant increase was measured in the contralateral hemisphere for the A1 and A2 segments of the ACA, the pericallosal artery, and the BA. A significant diameter increase was measured in all except 1 vessel of the controls. The vasodilatory capacity was significantly lower @entity850 compared with the A1 segment of the ACA and the P2 segment of the PCA in the controls. CONCLUSIONS: MRA combined with an @entity3791 provocation challenge can measure normal and impaired vasodilatory capacity of the cerebral vasculature.

Vasodilatory capacity of the cerebral vasculature in XXXX with carotid artery stenosis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity3791 :: ('MESH:D000086', 'Chemical') :: ['acetazolamide'] @entity4905 :: ('MESH:D002546', 'Disease') :: ['TIA'] @entity850 :: ('MESH:D003251', 'Disease') :: ['ICA stenosis', 'symptomatic ICA stenosis', 'ipsilateral to the ICA stenosis']
@entity1 :: (9606,Species) :: ['patients']
