Local infiltration of adjacent anatomic structures and soft tissues of the neck from well-differentiated @entity259 is a relatively infrequent occurrence. We report our experience with 21 such cases seen in our department over the past 20 years. All @entity1 were treated by total thyroidectomy and total or partial excision of the infiltrated adjacent structures. @entity1377 was the most frequent type of @entity5 seen. Following the definitive surgery, all @entity1 were scanned with radioactive @entity1496 (131I). In case of isotope entrapment, a curative dose 131I was given. All @entity1 in our series were required to receive thyroid hormone replacement. Four @entity1 died as a result of their disease. Uncontrolled @entity66 and distant metastases were present at the time of @entity204 . Three @entity1 died of unrelated causes. Two-thirds of the @entity1 are still alive (from 1 to 19 years after the treatment).

Locally aggressive XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1377 :: ('MESH:D002291', 'Disease') :: ['Papillary carcinoma'] @entity1496 :: ('MESH:D007455', 'Chemical') :: ['iodine'] @entity66 :: ('MESH:D004194', 'Disease') :: ['local disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumor'] @entity259 :: ('MESH:D013964', 'Disease') :: ['carcinoma of the thyroid gland'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity259 :: (MESH:D013964,Disease) :: ['differentiated thyroid carcinoma']
