PURPOSE: We evaluated the patterns of failure, survival rate, prognostic factors and treatment related complication in postoperative radiation treatment of @entity1 with @entity424 . MATERIALS AND METHODS: We retrospectively analyzed 25 @entity1 with histologically confirmed @entity424 treated between @entity1178 . 1990 and @entity1178 . 2001 with postoperative radiotherapy at Asan Medical Center. The study group comprised of 16 @entity1 and 9 @entity1 , with a median age of 23 years; including 6 supratentorial, 15 infratentorial and 4 spinal cord lesions. The extents of resection were ranked as either: gross total, near total, subtotal, partial resection or biopsy, with these types of surgical resection being performed in 13, 3, 6, 1 and 2 @entity1 , respectively. Twelve of the @entity1 had low grade @entity424 , and the other 13 a high grade @entity5 . The postoperative irradiation was administered using 4 MV or 6 MV photons, up to median dose of 55.0 Gy (range, 45.0~59.4 Gy), with the radiation field encompassing the preoperative @entity5 volume plus a 2 cm margin. Only 8 of the @entity1 received either pre- or postoperative chemotherapy. The median follow-up period of survivors was 43 months. RESULTS: Ten of the 25 @entity1 (40%) developed a recurrence, and 5 died. Of the 10 recurred @entity1 , 6 showed an in-field recurrence, and one developed both an in-field and an out of field recurrence. The remaining 3 @entity1 showed an out of field recurrence, including one case with a leptomeningeal recurrence. The 5-year overall survival, and progression-free, survival rates were 74.0 and 56.1%, respectively. The histological grades were statistically significant prognostic factors of the overall and progression-free survival rates. There were no significant treatment related complications, with the exception of one case of @entity7961 , which occurred 30 months after completion of the radiotherapy. CONCLUSION: The main pattern of recurrence was due to local failure. In order to improve the local control, and to reduce complications, advanced radiation treatment techniques, such as 3 dimensional radiotherapy, may be needed.

XXXX : a Retrospective Analysis of 25 Cases.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity424 :: ('MESH:D004806', 'Disease') :: ['ependymoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1178 :: ('3725', 'Gene') :: ['Jun'] @entity7961 :: ('MESH:C580003', 'Disease') :: ['panhypopituitarism']
@entity424 :: (MESH:D004806,Disease) :: ['Ependymoma']
