BACKGROUND: The authors present a retrospective analysis of 308 computed tomography (CT)-guided stereotactic biopsies in 300 @entity1 in order to evaluate the reliability and efficacy of the stereotactic biopsy for @entity1504 . METHOD: All @entity1 were suffering from @entity1504 and treated at Seoul National University Hospital between January 1993 and December 1999. Age ranged from three to 79 years (mean 41); the male to female ratio was 180:120. All @entity1 underwent CT-guided stereotactic biopsy for the histological verification and/or evacuation of the cyst using Riechert-Mundinger stereotactic system. FINDINGS: Histological diagnosis was made in 275 @entity1 (diagnostic yield 91.7%). Diagnostic yield was better in group with frozen section examination during the stereotactic procedure than the group without it (p=0.01). @entity1313 were more likely to be diagnosed in stereotactic biopsy than non-neoplastic lesions (p=0.02). Among 30 @entity1 who underwent craniotomy after the stereotactic biopsy, the histological diagnoses after the craniotomy were identical to those of the stereotactic biopsy in 29 @entity1 (diagnostic accuracy 96.7%). Two @entity1 died within seven days after the stereotactic biopsy (mortality 0.6%). The postoperative new @entity51 or aggravation of the neurological status was found in 19 @entity1 , including transient cases of seven @entity1 (permanent morbidity rate 3.9%). Histologically @entity11 and deeply-located lesions were the significant risk factors for the development of complications. In 148 cases, histological diagnosis of the stereotactic biopsy was different from the preoperative clinical diagnosis. Among these cases, the treatment plan was changed after stereotactic biopsy in 81 cases. CONCLUSIONS: Stereotactic biopsy for @entity1504 is a reliable and relatively safe procedure. It is also a very efficacious method especially in @entity1 who need histological confirmation for the treatment.

Stereotactic biopsy for XXXX : reliability and its impact on the planning of treatment.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['Neoplastic lesions'] @entity1504 :: ('MESH:D002561', 'Disease') :: ['intracranial lesions', 'undetermined intracranial lesions'] @entity11 :: ('MESH:D005910', 'Disease') :: ['malignant gliomas'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficit']
@entity1504 :: (MESH:D002561,Disease) :: ['intracranial lesions']
