Previous research suggests that @entity1 with @entity161 demonstrate deficits in a range of parameters of motor cortical and cognitive inhibition. I-wave facilitation and long-interval cortical inhibition (LICI) are two paired pulse transcranial magnetic stimulation paradigms that appear to assess aspects of cortical inhibitory function that have not previously been assessed in this @entity1 group. Eighteen @entity1 with @entity161 (nine medication-free) were compared with eight control subjects. We assessed resting motor threshold (RMT) levels, LICI and I-wave facilitation. RMT levels did not differ between the three groups. There was a significant overall difference in I-wave facilitation levels. Both @entity1 groups as compared with the control group showed increased facilitation. There were no differences between the groups in the measure of LICI. @entity1 with @entity161 appear to have increased I-wave facilitation. Increased I-wave facilitation suggests deficient function of cortical inhibitory GABAergic activity. This is consistent with previous research that has found deficient cortical inhibition in @entity1 with @entity161 .

A transcranial magnetic stimulation study of abnormal cortical inhibition in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patients'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
