UNASSIGNED: @entity955 ( @entity955 ) @entity1 are at high risk for @entity715 and vascular events related to their @entity943 and underlying systemic @entity731 . Ankle-Brachial Index (ABI) is a non-invasive tool in evaluating systemic @entity731 , useful in predicting @entity65 in general population; no data are available in @entity955 @entity1 . ARAPACIS is a prospective multicentre observational study performed by the Italian Society of Internal Medicine, analysing association between low ABI ( <=   0.90) and vascular events in @entity955 out- or in- @entity1 , enrolled in 136 Italian centres. A total of 2,027 @entity955 ( @entity955 ) @entity1 aged >   18 years from both sexes followed for a median time of 34.7 (interquartile range: 22.0-36.0) months, yielding a total of 4,614 @entity1 -years of observation. Mean age was 73    10 years old with 55   % male @entity1 . A total of 176 @entity1 (8.7   %) experienced a vascular event, with a cumulative incidence of 3.81   %/ @entity1 -year. ABI <=   0.90 was more prevalent in @entity1 with a vascular event compared with @entity1 free of vascular events (32.2 vs 20.2   %, p<   0.05). On Cox proportional hazard analysis, ABI <=   0.90 was an independent predictor of vascular events (hazard ratio (HR): 1.394, 95   % confidence interval (CI): 1.042-1.866; p=0.02), @entity204 (HR: 2.047, 95   % CI: 1.255-3.338; p=0.004) and MI (HR: 2.709, 95   % CI: 1.485-5.083; p=0.001). This latter association was also confirmed after excluding @entity1 with previous MI (HR: 2.901, 95   % CI: 1.408-5.990, p=0.004). No association was observed between low ABI and @entity64 /transient ischaemic attack (p=0.91). In conclusion, low ABI is useful to predict @entity204 in @entity955 @entity1 and may independently facilitate cardiovascular risk assessment in @entity955 @entity1 .

Ankle-Brachial Index and @entity65 in XXXX . The ARAPACIS Study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity955 :: ('MESH:D001281', 'Disease') :: ['Atrial fibrillation', 'AF', 'non-valvular AF', 'NVAF'] @entity204 :: ('MESH:D003643', 'Disease') :: ['MI and vascular death', 'vascular death'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombotic'] @entity943 :: ('MESH:D001145', 'Disease') :: ['cardiac arrhythmia'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular events']
@entity955 :: (MESH:D001281,Disease) :: ['atrial fibrillation']
