PURPOSE: To evaluate re-treatment with an additional course of low-dose irradiation in @entity1 with progressive or recurrent @entity1940 ( @entity1940 ). MATERIALS AND METHODS: Ten @entity1 who had received 14 Gy of external-beam radiation therapy in seven fractions for subfoveal @entity1940 were found to have recurrent or persistent @entity2295 at follow-up. They received an additional 15 Gy of radiation therapy administered in five daily fractions with a standard lens-sparing technique. Before reirradiation, visual acuity ranged from 20/80 to counting fingers. The median time between radiation courses was 6.5 months (range, 2-16 months). After re-treatment, the @entity1 were followed up with angiography and visual field testing. The median follow-up was 18.5 months (range, 12-21 months). RESULTS: Eight of 10 @entity1 (80%) maintained their visual acuity at 1 year and three of seven (43%) at 18 months. Visual acuity was stabilized in five of the 10 @entity1 at their last follow-up. No acute or late side effects of irradiation were noted. CONCLUSION: Additional radiation therapy in selected @entity1 with @entity1940 who have failed to benefit from previous irradiation is well tolerated and appears to stabilize the disease process in a substantial proportion of these @entity1 .

XXXX : treatment with reirradiation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2295 :: ('MESH:D015861', 'Disease') :: ['neovascularization'] @entity1940 :: ('MESH:D020256', 'Disease') :: ['choroidal neovascular membranes', 'CNVMs']
@entity1940 :: (MESH:D020256,Disease) :: ['Choroidal neovascular membranes']
