BACKGROUND: Data about the outcome and prognostic factors in the group of @entity1 with non-squamous cell advanced or recurrent @entity189 of the uterine cervix are limited. We compared the outcome of @entity1 with non-squamous with that of @entity957 after @entity902 -based combination chemotherapy as first line therapy for stage IV or recurrent @entity2622 . @entity1 AND METHODS: A total of 200 @entity1 with stage IV or recurrent @entity189 of the cervix received @entity902 -based combination chemotherapy and were included in our analysis. RESULTS: There were 58 @entity1 with non-squamous and 142 @entity1 with @entity957 . Response to chemotherapy was 53.5% in non-squamous vs. 43.5% in @entity957 . Histology was not an independent predictor of @entity5 response (P = 0.797). Response rates were lower in @entity1 with relapse only in a previously irradiated area in both squamous (26.9% vs. 53.5%, P = 0.005) and @entity957 (47.1% vs. 65%, P = 0.270). Weight loss was the only significant predictor of survival in non-squamous histology @entity1 (P < 0.0001). There was no significant difference in median survival between squamous (11.57 months [95% CI 9.35-13.79]) and @entity957 (19.05 months [95% CI 13.63-24.47]) (P = 0.064). After adjustment for independent prognostic factors (ECOG performance status and @entity353 ), differences in survival remained not significant. CONCLUSION: Our study showed a similar outcome for both @entity1544 treated with @entity902 -based combination chemotherapy.

The outcome of advanced or recurrent XXXX of the uterine cervix after @entity902 -based combination chemotherapy.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous carcinomas', 'squamous cell carcinomas', 'non-squamous carcinomas'] @entity2622 :: ('MESH:D002583', 'Disease') :: ['cervical carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas'] @entity1544 :: ('MESH:D018307', 'Disease') :: ['squamous and non-squamous stage IV or recurrent cervical carcinomas'] @entity902 :: ('MESH:D010984', 'Chemical') :: ['platinum']
@entity957 :: (MESH:D002294,Disease) :: ['non-squamous carcinoma']
