@entity1988 is one of the most serious complications of @entity1252 ( @entity1252 ). In the kidney, immune complexes and autoantibodies activate mesangial cells that secrete cytokines that can further amplify inflammatory processes. We present the case of a 42-year-old @entity1 with @entity1988 accompanied by periods of exacerbation of @entity1252 , with @entity39 -like @entity272 , @entity5144 without @entity272 , @entity4125 of the lower limb, @entity1910 , joint @entity158 , @entity221 , @entity4 with bilateral @entity3169 and @entity111 . The @entity1 underwent a dialytic treatment of hemodiafiltration with endogenous reinfusion. The technique uses the super-high-flux membrane Synclear 02 (SUPRA treatment) coupled with an adsorbent cartridge that has affinity for many toxins and mediators. @entity221 and joint @entity158 were immediately reduced after treatment and, subsequently, there was a notable reduction of the skin damage. @entity229 and immunosuppressive drugs were gradually reduced until complete suspension. High-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometer was performed for identification of proteins captured by a resin bed during a dialysis session of the @entity1 . This technique identified several biomarkers of @entity8 , uremic toxins, fragments of immunoglobulins, antigens involved in @entity1701 and a new marker (a-defensin) that correlated significantly with disease activity. The removal of these different proteins could possibly provide an explanation of the improvement in the @entity1 's symptoms and the normalization of her @entity1252 . SUPRA coupled with an adsorption may be a promising new technique for the treatment of @entity1988 .

Radical improvement of signs and symptoms in XXXX when treated with hemodiafiltration with endogenous reinfusion dialysis.

@entity1 :: ('9606', 'Species') :: ['patient', 'woman'] @entity8 :: ('MESH:D007674', 'Disease') :: ['kidney injuries'] @entity1910 :: ('MESH:D005076', 'Disease') :: ['petechial rash'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrotic'] @entity4 :: ('MESH:D004487', 'Disease') :: ['eyelid edema'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['Prednisone'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE', 'systemic lupus erythematosus'] @entity5144 :: ('MESH:D015535', 'Disease') :: ['psoriatic arthritis'] @entity4125 :: ('MESH:D011693', 'Disease') :: ['purpura'] @entity1988 :: ('MESH:D008181', 'Disease') :: ['Lupus nephritis', 'lupus nephritis'] @entity111 :: ('MESH:D011537', 'Disease') :: ['itching'] @entity1701 :: ('MESH:D016736', 'Disease') :: ['antiphospholipid syndrome'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesions', 'skin psoriasis'] @entity3169 :: ('MESH:D003229', 'Disease') :: ['conjunctival hyperemia'] @entity221 :: ('MESH:D005334', 'Disease') :: ['Fever', 'fever']
@entity1252 :: (MESH:D008180,Disease) :: ['systemic lupus erythematosus']
