INTRODUCTION: @entity1082 ) has been associated with benign and malignant lesions in different epitheliums. The relationship between specific genotypes of high-risk HPV and some @entity1 @entity5 is well established. The aim of this work was to detect the HPV genotypes present in @entity213 ( @entity213 ). METHODS: We evaluated 71 samples of @entity1 with histopathological diagnosis of @entity213 . The DNA extraction was conducted with the QIAGEN commercial kit. HPV detection and genotyping were performed by reverse hybridisation (INNO- @entity9377 ) following the commercial specifications. RESULTS: The mean age of the @entity1 evaluated was 60.7    13.11 years. The distribution of the lesions included 25 (35.20%) cases of @entity957 ( @entity957 ) of the oral cavity, 23 (32.39%) of larynx, 16 (22.50%) of the oropharynx, 4 (5.63%) of paranasal sinus, and 2 (2. 80%) cases of @entity957 of the nostril. Of the @entity1 , 78.9% were males, and of these 76% were @entity286 users and 67.6% were @entity167 consumers. The viral DNA was detected in 67.6% of the samples. The oral cavity and the larynx were the highest HPV-positivity sites with 35.40% and 29.10% respectively. The most frequent genotype was 16 as single infection (18.70%), or in combination with another HPV types. In the oral cavity and larynx the genotypes 16 or the combination 6 and 51 were present in 11.76% and 14.28%, respectively; and in the oropharynx the most frequent genotype was 16 in 22.50% of the cases, and in the paranasal sinus 50% presented infection with HPV-6. We observed that @entity5 with most advanced size and stage presented greater HPV positivity. CONCLUSIONS: This study shows a high percentage of HPV positivity in @entity957 is mainly associated with high-risk HPV. It is important to highlight that @entity1800 , especially @entity1799 , could be a risk factor in @entity213 progression.

@entity1082 detection in XXXX .

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'tumours'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma', 'SCC'] @entity9377 :: ('3988', 'Gene') :: ['LiPA'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral infection'] @entity1799 :: ('333760', 'Species') :: ['HPV-16'] @entity1082 :: ('10566', 'Species') :: ['Human Papillomavirus (HPV'] @entity213 :: ('MESH:C535575', 'Disease') :: ['HNSCC', 'head and neck squamous cell carcinoma']
@entity213 :: (MESH:C535575,Disease) :: ['head and neck squamous cell carcinoma']
