Resting-state studies conducted with @entity64 @entity1 are scarce. The study of brain activity and connectivity at rest provides a unique opportunity for the investigation of brain rewiring after @entity64 and plasticity changes. This study sought to identify dynamic changes in the functional organization of the default mode network ( @entity1233 ) of @entity64 @entity1 at three months after @entity64 . Eleven @entity1 (eight male and three female; age range: 48-72) with right cortical and subcortical @entity1188 and 17 controls (eleven males and six females; age range: 57-69) were assessed by neurological and neuropsychological examinations and scanned with resting-state functional magnetic ressonance imaging. First, we explored group differences in functional activity within the @entity1233 by means of probabilistic independent component analysis followed by a dual regression approach. Second, we estimated functional connectivity between 11 @entity1233 nodes both locally by means of seed-based connectivity analysis, as well as globally by means of graph-computation analysis. We found that @entity1 had greater @entity1233 activity in the left precuneus and the left anterior cingulate gyrus when compared with healthy controls (P   <   0.05 family-wise error corrected). Seed-based connectivity analysis showed that @entity64 @entity1 had significant impairment (P   =   0.014; threshold   =   2.00) in the connectivity between the following five @entity1233 nodes: left superior frontal gyrus (lSFG) and posterior cingulate cortex (t   =   2.01); left parahippocampal gyrus and right superior frontal gyrus (t   =   2.11); left parahippocampal gyrus and lSFG (t   =   2.39); right parietal and lSFG (t   =   2.29). Finally, mean path length obtained from graph-computation analysis showed positive correlations with semantic fluency test (r s    =   0.454; P   =   0.023), phonetic fluency test (r s    =   0.523; P   =   0.007) and the mini mental state examination (r s    =   0.528; P   =   0.007). In conclusion, the ability to regulate activity of the @entity1233 appears to be a central part of normal brain function in @entity64 @entity1 . Our study expands the understanding of the changes occurring in the brain after @entity64 providing a new avenue for investigating lesion-induced network plasticity. Hum Brain Mapp, 2014.    2014 The Authors @entity1 Brain Mapping Published by Wiley Periodicals, Inc.

Impairment of functional integration of the default mode network correlates with cognitive outcome at three months after XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Human'] @entity1233 :: ('CHEBI:35807', 'Chemical') :: ['DMN'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['ischemic infarctions']
@entity64 :: (MESH:D020521,Disease) :: ['stroke']
