BACKGROUND: A syndrome variously combining @entity1897 , visceromegaly, @entity2744 , @entity1581 , and skin changes ( @entity7555 ) is a rare variant of @entity1581 with @entity66 manifestations. Acute @entity385 in @entity1 with @entity7555 have rarely been reported, and the pathophysiologic mechanism of this disease is unknown. @entity2002 is reported to be an independent risk factor for @entity66 and is correlated with the @entity650 level in the plasma. The serum level of @entity650 is high in the active stage of @entity7555 . OBJECTIVE: To describe the neuroimaging findings and @entity2002 levels in @entity1 with @entity7555 . DESIGN: Case series. SETTING: The neurology department of a tertiary referral center. METHODS: Three @entity1 with an acute @entity385 associated with @entity7555 underwent magnetic resonance imaging, diffusion-weighted imaging, magnetic resonance angiography, transcranial Doppler ultrasonography, and serum @entity2002 level and serum @entity1851 level analysis. The serum @entity2002 level before the @entity64 was collected retrospectively from the hospital medical records. RESULTS: There was an elevated @entity2002 level in all of the @entity1 . In 2 @entity1 , unilateral or bilateral end artery border-zone @entity1188 were observed on the brain magnetic resonance imaging scan. The serum @entity2002 level was high before the @entity64 in 2 @entity1 . CONCLUSIONS: The @entity7555 can be associated with @entity64 , particularly end artery border-zone @entity1188 . We suggest that an elevated @entity2002 level might play a role in the pathogenesis of @entity64 .

XXXX associated with @entity385 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity650 :: ('3569', 'Gene') :: ['interleukin 6'] @entity2002 :: ('2244', 'Gene') :: ['Fibrinogen', 'fibrinogen'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity66 :: ('MESH:D004194', 'Disease') :: ['cerebrovascular disease', 'multisystemic'] @entity1581 :: ('MESH:D010265', 'Disease') :: ['monoclonal gammopathy', 'plasma cell dyscrasia'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral neuropathy'] @entity2744 :: ('MESH:C567425', 'Disease') :: ['endocrinopathy'] @entity7555 :: ('MESH:D016878', 'Disease') :: ['POEMS syndrome'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarctions', 'infarcts'] @entity385 :: ('MESH:D002544', 'Disease') :: ['cerebral infarction', 'ischemic strokes']
@entity7555 :: (MESH:D016878,Disease) :: ['POEMS syndrome']
