OBJECTIVES: The purpose of this retrospective study was to evaluate the diagnostic performance of double-echo gradient chemical shift (GRE) magnetic resonance (MR) imaging for the differentiation of @entity359 with minimal fat (mfAML) from other homogeneous solid @entity703 . METHODS: Between 2005 and 2010 in two institutions, all histologically proven homogenous solid @entity703 imaged with computed tomography and MR imaging, including GRE sequences, have been retrospectively selected. A total of 118 @entity1 (mean age: 61 years; range: 20-87) with 119 @entity5 were included. Two readers measured independently the signal intensity (SI) on GRE images and calculated SI index (SII) and @entity5 -to-spleen ratio (TSR) on in-phase and opposed-phase images. Intra- and interreader agreement was obtained. Cut-off values were derived from the receiver operating characteristic (ROC) curve analysis. RESULTS: Twelve mfAMLs in 11 @entity1 were identified (mean size: 2.8cm; range: 1.2-3.5), and 107 @entity5 (3.2cm; 1-7.8) in 107 @entity1 . The intraobserver reproducibility of SII and TSR was excellent with an intraclass correlation coefficient equal to 0.99 [0.98-0.99]. The coefficient of correlation between the readers was 0.99. The mean values of TSR for mfAMLs and non-mfAMLs were -7.0  22.8 versus -8.2  21.2 for reader 1 and -6.7  22.8 versus -8.4  20.9 for reader 2 respectively. No significant difference was noticed between the two groups for SII (p=0.98) and TSR (p=0.86). Only 1 out of 12 mfAMLs and 11 of 107 @entity5 presented with a TSR inferior to -30% (p=0.83). CONCLUSION: In a routine practice, GRE sequences cannot be a confident tool to differentiate renal mfAMLs from other homogeneous solid @entity703 .

Double-echo gradient chemical shift MR imaging fails to differentiate minimal fat renal XXXX from other homogeneous solid @entity703 .

@entity359 :: ('MESH:D018207', 'Disease') :: ['angiomyolipomas'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'non-AML tumors', 'tumors'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal tumors']
@entity359 :: (MESH:D018207,Disease) :: ['angiomyolipomas']
