The objective of this study was to support our hypothesis that surgical resection of abdominal metastases of @entity320 , regardless of symptomatology, could provide prolonged palliation and improved survival. We performed a retrospective chart review at M.D. Anderson @entity5 Center. A series of 251 @entity320 @entity1 (stages I, II, or III at registration) who developed intraabdominal metastases during follow-up were studied. Altogether, 96 @entity1 underwent 119 laparotomies; 51 underwent endoscopic or percutaneous procedures; and 116 @entity1 were treated medically. Surgery was associated with a median survival of 11 months, significantly longer than that with other treatment (p < 0.001). @entity5 was extirpated during 37% of the first laparotomies, and in an additional 33% very good palliation was achieved with incomplete resection. @entity5 extirpation was associated with 10-month symptom-free survival (SFS), significantly longer than that with any other approach (p < 0.0001). In the nonsurgically treated @entity1 , good palliation was achieved in 8% to 17% of @entity1 with no complete response. The median SFS after surgery was 5 months, but 23% of @entity1 were symptom-free more than 12 months; 87 @entity1 with minimal symptoms; and 72 severely symptomatic @entity1 underwent surgery. Complete resection was feasible in 42% and 34%, respectively. Surgery was associated with 12 months median survival in both groups. There was a significant survival benefit from surgery in @entity1 with gastrointestinal (GI) tract metastases in contrast to those who had non-GI metastases. For the 96 surgically treated @entity1 , a time interval of more than 4 years between diagnosis of the @entity75 and the abdominal recurrence predicted decreased risk of @entity204 (p = 0.038). The 30-day postoperative complication and mortality rates were 19.0% and 3.3%, respectively. Complete surgical resection of @entity320 metastases in the abdomen is associated with median and symptom-free survival benefits. Symptomatic and asymptomatic @entity1 benefit equally, especially if abdominal metastases appear more than 4 years after the initial diagnosis and do not involve @entity344 . Less than complete resection can provide durable palliation.

Surgery for abdominal metastases of cutaneous XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Tumor', 'Cancer'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesion'] @entity344 :: ('MESH:D005767', 'Disease') :: ['non-GI viscera'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma']
@entity320 :: (MESH:D008545,Disease) :: ['melanoma']
