AIM: To compare the genomic variability and the multiple colonization of @entity1534 ( @entity1534 ) in @entity1 with chronic @entity3621 from two Colombian populations with contrast in the risk of developing @entity356 ( @entity356 ): T  querres-Nari  o (High risk) and Tumaco-Nari  o (Low risk). METHODS: Four hundred and nine @entity1 from both genders with @entity1109 were studied. Seventy-two @entity1 were included in whom @entity1534 was isolated from three anatomic regions of the gastric mucosa, (31/206) of the high risk population of @entity356 (T  querres) and (41/203) of the low risk population of @entity356 (Tumaco). The isolates were genotyped by PCR-RAPD. Genetic diversity between the isolates was evaluated by conglomerates analysis and multiple correspondence analyses. RESULTS: The proportion of virulent genotypes of @entity1534 was 99% in T  querres and 94% in Tumaco. The coefficient of similarity of Nei- @entity8357 showed greater genetic diversity among isolates of T  querres (0.13) than those of Tumaco (0.07). After adjusting by age, gender and type of @entity3621 , the multiple colonization was 1.7 times more frequent in T  querres than in Tumaco (P = 0.05). CONCLUSION: In T  querres, high risk of @entity356 there was a greater probability of multiple colonization by @entity1534 . From the analysis of the results of the PCR-RAPD, it was found higher genetic variability in the isolates of @entity1534 in the population of high risk for the development of @entity356 .

Genomic variability of XXXX isolates of gastric regions from two Colombian populations.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8357 :: ('D008094', 'Chemical') :: ['Li'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['dyspeptic symptoms'] @entity3621 :: ('MESH:D005756', 'Disease') :: ['gastritis'] @entity1534 :: ('210', 'Species') :: ['H. pylori', 'Helicobacter pylori'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'GC']
@entity1534 :: (210,Species) :: ['Helicobacter pylori']
