BACKGROUND: Soluble adhesion molecules are elevated in a number of inflammatory conditions. AIMS: To investigate the correlation of soluble intercellular adhesion molecule-1 (sICAM-1) and sE-selectin with the activity of @entity29 ( @entity29 ). METHODS: sICAM-1 and sE-selectin were measured by an enzyme-linked immunosorbent assay (ELISA) in 53 @entity1 with @entity31 ( @entity31 ) and 38 @entity1 with @entity30 ( @entity30 ). RESULTS: @entity1 with active @entity31 and @entity30 had significantly higher sICAM-1 than @entity1 with inactive disease and controls. @entity1 with pancolitis had significantly higher levels than @entity1 with @entity1960 . There was a significant difference in sE-selectin levels between @entity1 with active @entity30 and control sICAM-1. sE-selectin did not correlate with the Harvey Bradshaw index (HBI). @entity1851 (CRP) and microalbuminuria were better markers than sICAM-1 or sE-selectin which correlated with serum @entity5 @entity39 factor ( @entity310 . CONCLUSION: sICAM-1 and sE-selectin are elevated in the serum of @entity1 with @entity29 but CRP and microalbuminuria reflect clinical disease activity more accurately. This study does not support the routine use of soluble adhesion molecules as disease activity markers in @entity29 .

Soluble adhesion molecules in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity310 :: ('7124', 'Gene') :: ['TNF)-alpha'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease', 'IBD'] @entity1960 :: ('MESH:D003092', 'Disease') :: ['distal colitis'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein']
@entity29 :: (MESH:D015212,Disease) :: ['inflammatory bowel disease']
