OBJECTIVE: We aimed at developing and testing a Dutch health-related quality of life measure for @entity263 @entity1 . METHODS: Scales on urinary and bowel function and bother from the UCLA @entity263 Index (PCI) underwent formal linguistic and cultural translation. PCI sexual scales were replaced by an existing Dutch sexual activities module (SAc). After qualitative pilot testing 389 @entity1 with @entity263 (mean age 67 +/- 7 years) completed the measure before and at 2 time points after primary treatment. Psychometric properties (feasibility, score distribution, reliability, construct validity and responsiveness to change) of the new instrument were analyzed. RESULTS: Response rates ranged from 93% at baseline to 87% after treatment. Urinary and bowel function scales showed Cronbach's alphas >0.7. Urinary function and bother, and bowel function and bother were significantly correlated. Pre- vs. post-prostatectomy effect sizes were >0.9 only for urinary scales; while pre- vs. post-radiotherapy effect sizes were >0.75 only for bowel scales. Six months after baseline @entity323 was reported by 64% of respondents, either as a problem in sexual activity or as a reason for not being sexually active. CONCLUSION: The Dutch PCI and SAc performed well in @entity1 treated for early @entity5 .

Measuring disease specific quality of life in XXXX : the Dutch experience.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity323 :: ('MESH:D007172', 'Disease') :: ['erectile dysfunction'] @entity263 :: ('MESH:D011471', 'Disease') :: ['localized prostate cancer', 'Prostate Cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['stage prostate cancer']
@entity263 :: (MESH:D011471,Disease) :: ['localized prostate cancer']
