BACKGROUND: The effect of pulmonary rehabilitation (PR) on the EuroQol Group's 5-dimension questionnaire (EQ-5D) in @entity1030 has been poorly investigated. In addition, conflicting results were reported about the visual analog scale component of EQ-5D (EQ-VAS). The purpose of this study was to evaluate the responsiveness of EQ-VAS to PR and its relationship with clinical and functional parameters in subjects with @entity1030 , as well as to define the @entity922 ( @entity922 ) estimate for the EQ-VAS after PR. METHODS: A total of 468 in- @entity1 with stable moderate-to-severe @entity1030 , allocated to a 3-wk PR program, were retrospectively evaluated. EQ-VAS was assessed before and after PR, and its relationship with baseline pulmonary function, changes in 6-min walk test, and baseline, and transitional @entity1353 index (BDI/TDI) after PR were evaluated. Using an anchor-based approach and receiver operating characteristic curves, the EQ-VAS change cutoff that identified subjects achieving the known @entity922 for TDI after PR was identified. RESULTS: Four hundred and thirty-nine subjects (94%, mean FEV1 55.3% predicted) completed pre- and post-PR EQ-VAS scores. After PR, EQ-VAS increased from 58    17 to 72    15 (/\EQ-VAS 14    12, P < .001). /\EQ-VAS was negatively related to baseline FEV1 (r = -0.32, P < .001) and positively to TDI (r = 0.50, P < .001) and 6-min walk distance (r = 0.46, P < .001) changes. Receiver operating characteristic curves identified an EQ-VAS change cutoff of 8 as the best discriminating value to identify the @entity922 for TDI (0.78 sensitivity and 0.81 specificity; area under curve: 0.845, P < .001). CONCLUSIONS: Our study shows that, in in- @entity1 with stable moderate-to-severe @entity1030 , EQ-VAS is a valid and reliable tool to assess the responsiveness to PR, with an estimated @entity922 of 8 points. The EQ-VAS can be a practical alternative to more time-consuming measures of health-related quality of life.

Estimation of Minimal Clinically Important Difference in EQ-5D Visual Analog Scale Score After Pulmonary Rehabilitation in Subjects With XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity922 :: ('MESH:D013568', 'Disease') :: ['minimal clinically important difference', 'MCID'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['COPD']
@entity1030 :: (MESH:D029424,Disease) :: ['COPD']
