BACKGROUND: @entity4035 of childhood is a rare disease with an estimated prevalence of approximately 1/1,000,000. The disease manifests around the age of three to eight years and progresses with symptoms of early fatigue, @entity425 , @entity4 and @entity2693 . The resulting functional limitations are often described as having a waddling gait. Walking is difficult and can be managed with multilevel compensation movements only. Aims of this study were to determine typical malpositions that arise during walking and to identify preventive strategies to reduce @entity16 . METHODS: This study presents data of three-dimensional gait analysis of nine @entity1 with @entity4035 of childhood (   =2;    =7; 13.3y; 47.0kg; 1.39m; BMI: 24.2kg/m(2)) performed with eight infrared cameras and the Plug-in-Gait Model. For comparison of spatiotemporal and kinematic parameters with age-matched healthy controls (   =6;    =3; 13.4y; 49.0kg; 1.61m; BMI: 18.9kg/m(2)), the Mann-Whitney U-test was applied with a significance level of P<0.05. FINDINGS: The @entity1 had a significantly lower height, but higher BMI. Walking speed was reduced with wide, but short steps and significant @entity154 in the pelvis, hips, knees and ankles. Small ranges of motion in propulsion-supporting movements were typical, especially in the sagittal plane. The gait analysis revealed dominant compensatory movements in @entity530 and rotation. INTERPRETATION: The deficits can be attributed to pronounced @entity425 plus @entity73 and @entity158 . Therapeutic preventive strategies therefore should consider continuous muscle power exercises, stretching programmes and restrictive weight control.

Biomechanics of walking in adolescents with XXXX of childhood leads to physical activity recommendations as therapeutic focus.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4035 :: ('MESH:C535387', 'Disease') :: ['progressive pseudorheumatoid arthropathy', 'Progressive pseudorheumatoid arthropathy'] @entity154 :: ('MESH:D000013', 'Disease') :: ['motion anomalies'] @entity4 :: ('MESH:D004487', 'Disease') :: ['joint swelling'] @entity16 :: ('MESH:D009422', 'Disease') :: ['excessive joint damage'] @entity73 :: ('MESH:D003072', 'Disease') :: ['functional joint impairment'] @entity425 :: ('MESH:D018908', 'Disease') :: ['muscle weakness'] @entity530 :: ('MESH:D010386', 'Disease') :: ['pelvic obliquity'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity2693 :: ('MESH:C566112', 'Disease') :: ['stiffness']
@entity4035 :: (MESH:C535387,Disease) :: ['progressive pseudorheumatoid arthropathy']
