We report a case of chronic active @entity2025 (CAEBV) associated with skin @entity203 mimicking @entity54801 ( @entity54801 ) in a 4-year-old @entity1 . The @entity1 had repeated episodes of @entity39 on the face, scalp, and bilateral forearms one year before the first visit to our department. General symptoms including fever, @entity409 , and cervical lymph node swelling were noted three months before the first visit. At the first visit, small, bean-sized, erythemic papules with central @entity39 were observed on the face and anterior chest wall. Thumb-sized ulcers with crust were present on the bilateral forearms. Histopathological examination of an @entity75 in the submandibular area revealed @entity8286 with a thick crust, mild spongiosis in the epidermis, and a dense infiltration of lymphoid cells into the dermis and perivascular space. Laboratory examination showed EBNA x 40, EBV VCA IgG x 1,280, and EBV DNA (PCR) 8 x 10(4). EBV-encoded small nuclear RNA (EBER) positive cells were detected in the dermis by an in situ hybridization (ISH) method. Large granular lymphocytes (65%) with the NK cell phenotype were found in the peripheral blood. A real time PCR method showed 171,741 copies/ micro g DNA in CD 16 positive cells. Although latent EBV infection-associated @entity203 have been documented, detailed skin manifestations in CAEBV are less well known.

XXXX in a @entity1 with @entity2025 .

@entity1 :: ('9606', 'Species') :: ['patient', 'boy'] @entity54801 :: ('MESH:D006837', 'Disease') :: ['HV', 'hydroa vacciniforme'] @entity39 :: ('MESH:D009336', 'Disease') :: ['vesiculo-necrotic eruptions', 'necrosis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['erythematous lesion'] @entity203 :: ('MESH:D003875', 'Disease') :: ['eruptions'] @entity409 :: ('MESH:D008107', 'Disease') :: ['hepatosplenomegaly, abnormal liver function'] @entity8286 :: ('MESH:D010241', 'Disease') :: ['parakeratosis'] @entity2025 :: ('MESH:D020031', 'Disease') :: ['Epstein-Barr (EB) virus infection']
@entity54801 :: (MESH:D006837,Disease) :: ['Hydroa vacciniforme-like eruptions']
