BACKGROUND AND PURPOSE: Rehabilitation care after @entity64 is highly variable and increasingly shorter in duration. The effect of therapeutic exercise on @entity73 after @entity64 is not clear. The objective of this study was to determine whether a structured, progressive, physiologically based exercise program for subacute @entity64 produces gains greater than those attributable to spontaneous recovery and usual care. METHODS: This randomized, controlled, single-blind clinical trial was conducted in a metropolitan area and 17 participating healthcare institutions. We included @entity1 with @entity64 who were living in the community. One hundred @entity1 (mean age, 70 years; mean Orpington score, 3.4) consented and were randomized from a screened sample of 582. Ninety-two subjects completed the trial. Intervention was a structured, progressive, physiologically based, therapist-supervised, in-home program of thirty-six 90-minute sessions over 12 weeks targeting flexibility, strength, balance, endurance, and @entity2319 . Main outcome measures were postintervention strength (ankle and knee isometric peak torque, grip strength), upper- and lower-extremity motor control (Fugl Meyer), balance (Berg and functional reach), endurance (peak aerobic capacity and exercise duration), @entity2319 (Wolf Motor Function Test), and mobility (timed 10-m walk and 6-minute walk distance). RESULTS: In the intention-to-treat multivariate analysis of variance testing the overall effect, the intervention produced greater gains than usual care (Wilk's lambda=0.64, P=0.0056). Both intervention and usual care groups improved in strength, balance, upper- and lower-extremity motor control, @entity2319 , and gait velocity. Gains for the intervention group exceeded those in the usual care group in balance, endurance, peak aerobic capacity, and mobility. Upper-extremity gains exceeded those in the usual care group only in @entity1 with higher baseline function. CONCLUSIONS: This structured, progressive program of therapeutic exercise in @entity1 who had completed acute rehabilitation services produced gains in endurance, balance, and mobility beyond those attributable to spontaneous recovery and usual care.

Randomized clinical trial of therapeutic exercise in subacute XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'persons'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impairments and functional limitations'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity2319 :: ('MESH:D003638', 'Disease') :: ['upper-extremity function']
@entity64 :: (MESH:D020521,Disease) :: ['stroke']
