This is the case report of a 38-year-old @entity1 who presented with a mass of the right broad ligament that was diagnosed as a female @entity5 of probable Wollfian origin (FATWO). The @entity1 was treated with a simple mass excision. Three years after the excision, the @entity1 presented with uterine @entity548 . A total abdominal hysterectomy was advised. Intraoperative histologic consultation showed a poorly differentiated @entity5 on the surface of the left ovary. After extensive immunohistochemistry analysis and after reviewing the histology slides from the @entity5 , the final diagnosis was concluded to be recurrent FATWO on the surface of the ovary. @entity2467 immunohistochemistry was found to be strongly positive. Polymerase chain reaction amplification of @entity2467 genes on exons 9, 11, 13, and 17 and of @entity3820 gene on exons 12 and 18 showed no mutational changes. Owing to the limited options in treating recurrent disease and the lack of prognostic factors for recurrence or @entity3 , the @entity1 was started on 400 mg of @entity2213 mesylate therapy for 6 months. In addition, the @entity1 is undergoing continuous follow-up by computed tomographic imaging every 6 months. As chemotherapy and radiation therapy for recurrent or metastatic FATWO are most often unsuccessful, a molecular targeted therapy, such as @entity669 kinase inhibitor, could be considered. However, collective data are needed from multiple centers to determine its effectiveness in these @entity1 .

XXXX of probable Wolffian origin (FATWO) with recurrence 3 years postsurgery.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'patient'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'adnexal tumor', 'primary tumor'] @entity3820 :: ('5159', 'Gene') :: ['PDGFR'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity2467 :: ('3815', 'Gene') :: ['C-kit'] @entity669 :: ('CHEBI:18186', 'Chemical') :: ['tyrosine'] @entity2213 :: ('MESH:C097613', 'Chemical') :: ['imatinib']
@entity5 :: (MESH:D009369,Disease) :: ['Female adnexal tumor']
