The incidence rate of @entity3557 ( @entity3557 ) has increased over the past decades, but the pathogenesis remains unclear. @entity6992 , located in pre-miR-146a, has been studied in PTCs with different ethnicity, but the results were inconsistent. Here we evaluate the association between @entity6992 polymorphism and @entity3557 and investigate the effect of this polymorphism on @entity1 ' clinicopathological characteristics. 1238 @entity3557 @entity1 and 1275 controls, all Han population, from Northern China, were included in our study. @entity6992 was genotyped using Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS). Analysis of inheritance model was performed using the SNPStats program. Strength of association was assessed by odds ratio (OR) and 95% confidence interval (CI). Overall, no statistical difference in @entity6992 genotype distribution and allelic frequencies between cases and controls was found, and @entity1 with different genotypes had similar clinicopathological characteristics in terms of stage, location, concurrent of @entity5 , and @entity1374 , while, as the number of G alleles increased, proportion of @entity1 aged >= 45 years and those without @entity3 increased (P trend < 0.001 and P trend = 0.003, resp.). However, no association remained significant after Bonferroni correction under any model of inheritance. Our results suggest no association between @entity6992 polymorphism with @entity3557 and @entity1 ' clinicopathological characteristics.

Association of Pre-miR-146a @entity6992 Polymorphism with XXXX .

@entity3557 :: ('MESH:C536915', 'Disease') :: ['PTC', 'papillary thyroid cancer'] @entity6992 :: ('rs2910164', 'SNP') :: ['rs2910164'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['benign thyroid tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroiditis']
@entity3557 :: (MESH:C536915,Disease) :: ['Papillary Thyroid Cancer']
