INTRODUCTION: @entity1 with @entity792 may suffer from hoarseness and @entity1740 because of anatomical and functional alterations. OBJECTIVES: To assess the prevalence of @entity7364 in @entity627 @entity1 and its impact on their quality of life (QOL). To analyze the association of @entity1740 in @entity1 with @entity309 ( @entity309 ), @entity1252 ( @entity1252 ), and @entity751 ( @entity751 ). To determine if @entity1740 during the acute phase of these diseases are correlated with specific biochemical parameters. METHODS: Present an observational and transverse analytic study of 140 @entity1 selected from February 2009 to January 2010. The subjects (80) were diagnosed with @entity309 (44), @entity1252 (32), and @entity751 (4), and the control group (60) presented no @entity1740 or @entity627 . @entity1 were evaluated using the Voice Handicap Index (VHI) and a three items outcome scale (TIOS). A biochemical and C-reactive protein study was performed on 40 @entity1 with a disease outbreak, measuring their complement, sedimentation velocity (VSG), and anti-DNA antibodies. RESULTS: The prevalence of @entity7364 among the subjects was 32-38% as opposed to 5-8% in the control group. The @entity627 @entity1 presented an odds ratio (OR) for @entity7364 of 2.82 (VHI) and 5.04 (TIOS) when compared with healthy individuals (P<0.05). We found statistically significant differences in functional, physical, occupational, and emotional subscales of these tests. No significant differences were found when studying the biochemical parameters. A higher incidence of @entity1740 (OR=3.07) was associated with @entity1252 , followed by @entity309 (OR=2.8; 95% CI). CONCLUSIONS: @entity262 may associate @entity1740 . @entity1 with @entity1252 are those who develop these disorders more frequently. The biochemical parameters most affected during a crisis are VSG and anti-DNA antibodies.

The prevalence of XXXX , its association with immunomediated diseases and correlation with biochemical markers.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity627 :: ('MESH:D012216', 'Disease') :: ['rheumatic', 'rheumatic diseases'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE', 'systemic lupus erythematosus'] @entity262 :: ('MESH:D034721', 'Disease') :: ['Systemic immunomediated diseases'] @entity7364 :: ('MESH:D055154', 'Disease') :: ['dysphonia'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmune diseases'] @entity751 :: ('MESH:D013577', 'Disease') :: ['Sj  gren syndrome', 'SS'] @entity1740 :: ('MESH:D014832', 'Disease') :: ['voice disorders'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA']
@entity7364 :: (MESH:D055154,Disease) :: ['dysphonia']
