OBJECTIVE: To compare @entity282 relief and pulmonary function in @entity1 after thoracoabdominal esophagectomy treated by continuing perioperative @entity1514 epidural anesthesia or changing to parenteral opioids. DESIGN: Prospective, randomized study. SETTING: University teaching hospital. @entity1 : Thirty-three @entity1 undergoing thoracoabdominal esophagectomy. INTERVENTIONS: General anesthesia was combined with @entity1514 epidural anesthesia during surgery. The @entity1 either continued with @entity1337 (n = 18) or were switched to @entity1 -controlled analgesia with intravenous @entity1286 (n = 15) for 5 postoperative days. @entity158 scores were estimated twice daily, at rest and after mobilization. Peak expiratory flow, forced expiratory volume, and vital capacity were measured the day before surgery, postoperative day 2, and postoperative day 6. Adverse events and complications were recorded. MEASUREMENTS AND MAIN RESULTS: At rest, there were no differences in @entity158 relief between the groups. @entity158 scores at mobilization showed a significantly lower value in the epidural group (p < 0.027). No intergroup differences were found regarding pulmonary function, which decreased on postoperative day 2, but was improved on postoperative day 6. CONCLUSION: Continuation of intraoperative @entity1514 epidural anesthesia for 5 postoperative days provides @entity158 relief at mobilization compared with a switch to @entity1 -controlled analgesia with intravenous @entity1286 . There was no intergroup difference in the impact on measures of pulmonary function.

@entity158 relief after esophagectomy: XXXX is better than parenteral opioids.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PARTICIPANTS'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['thoracic epidural analgesia'] @entity1514 :: ('MESH:D013896', 'Disease') :: ['thoracic'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'better pain', 'pain'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain']
@entity1337 :: (MESH:D000699,Disease) :: ['Thoracic epidural analgesia']
