Three @entity1 aged 25, 34 and 22 years respectively, experienced high-altitude @entity4 during a climbing holiday. The first @entity1 presented with complaints arising from a fast ascent to high altitude and was treated with @entity3791 and rapid descent. She recovered without any complications. The second @entity1 developed symptoms during the night, which were not recognised as high-altitude @entity4 . The next morning she died while being transported down on a stretcher without having received any medication or @entity26 . The third case was not a specific presentation of high-altitude @entity4 but autopsy revealed @entity4 . This @entity1 had already been higher up on the mountain before she developed complications. The cases illustrate the seriousness of this avoidable form of high @entity221 . The current Dutch national guidelines advise against the use of medication by lay @entity1 . A revision is warranted: travellers to high altitude should be encouraged to carry @entity3791 , @entity594 and @entity288 on the trip. Travel guides ought to be trained to use these drugs. In addition climbing travellers should be encouraged to adopt appropriate preventive behaviour and to start descending as soon as signs of high-altitude @entity4 develop.

[Serious and sometimes fatal consequences of high-altitude XXXX ].

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'patient', 'people'] @entity4 :: ('MESH:D004487', 'Disease') :: ['pulmonary oedema'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity3791 :: ('MESH:D000086', 'Chemical') :: ['acetazolamide'] @entity594 :: ('MESH:D009543', 'Chemical') :: ['nifedipine'] @entity221 :: ('MESH:D005334', 'Disease') :: ['altitude illness'] @entity288 :: ('MESH:D000305', 'Chemical') :: ['corticosteroids']
@entity4 :: (MESH:D004487,Disease) :: ['pulmonary oedema']
