OBJECTIVE: To evaluate the performance of quantitative diffusion-weighted imaging (DWI) correlated with T2 signal in differentiating non-fatty benign from @entity5 . MATERIAL AND METHODS: A total of 76 @entity1 with a histologically confirmed @entity8650 (46 benign and 30 malignant) were prospectively included in this ethics committee approved study. All @entity1 signed an informed consent and underwent MRI with DWI with two b values (0 and 600). ADC values from the solid components of these @entity5 were obtained and were correlated with the lesion's signal intensity on T2-weighted fat-saturated sequences. ADC values were obtained from adjacent normal muscle to allow calculation of @entity5 /muscle ADC ratios. RESULTS: There were 58 hyperintense and 18 iso or hypointense lesions. All hypointense lesions were benign. The mean ADC values for benign and @entity5 were 1.47        0.54   *   10(-3) and 1.17        0.38   *   10(-3) mm(2)/s respectively (p   <   0.005). The mean ADC ratio in benign iso or hypointense @entity5 was significantly lower than that of hyperintense ones (0.76        0.21 versus 1.58        0.82 - p   <   0.0001). An ADC ratio lower than 0.915 was highly specific for @entity5 (96.4  %), whereas an ADC ratio higher than 1.32 was highly sensitive for benign lesions (90  %). CONCLUSION: ADC analysis can be useful in the initial characterization of T2 hyperintense non-fatty soft tissue masses, although this technique alone is not likely to change @entity1 management.

Diffusion-weighted magnetic resonance imaging for the initial characterization of XXXX : correlation between T2 signal intensity and ADC values.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignant tumors', 'malignancy', 'tumors'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity8650 :: ('MESH:D012983', 'Disease') :: ['non-fatty soft tissue tumors']
@entity8650 :: (MESH:D012983,Disease) :: ['non-fatty soft tissue tumors']
