UNASSIGNED: OBJECT @entity432 is a known complication after external ventricular drain (EVD) placement. There have been no prospective published series that primarily evaluate the incidence of and risk factors for @entity432 . These phenomena are investigated using a prospective database. METHODS An ongoing prospective study of all @entity1 undergoing frontal EVD placement in the Neurosurgery Intensive Care Unit at the University of Florida was accessed for the purposes of this analysis. Demographic, procedural, and radiographic data were recorded prospectively and retrospectively. The need for catheter irrigation or replacement was meticulously documented. Univariate and multivariate regression analyses were performed. RESULTS Ninety-eight of 101 total enrolled @entity1 had accessible data, amounting to 131 total catheters and 1076 total catheter days. Nineteen percent of @entity1 required at least 1 replacement. Forty-one percent of catheters developed at least 1 temporary occlusion, with an average of 2.4 irrigations per @entity1 . @entity932 occurred in 28% of @entity1 after the first EVD placement (2% resulting in new @entity51 ) and in 62% of @entity1 after 1 replacement. The cost of occlusion is estimated at  615 per enrolled patient. Therapeutic anticoagulation and use of small EVD catheters were statistically significant predictors of @entity432 (p = 0.01 and 0.04, respectively). CONCLUSIONS @entity432 is frequent and imparts a significant burden in terms of @entity1 morbidity, physician upkeep, and cost. This study suggests that developing strategies or devices to prevent @entity432 , such as the preferential use of larger diameter catheters, may be beneficial in reducing the burden associated with ventriculostomy malfunction.

The burden and risk factors of XXXX in a high-volume cerebrovascular practice: results of an ongoing prospective database.

@entity432 :: ('MESH:D001157', 'Disease') :: ['permanent occlusion', 'EVD occlusion', 'Ventriculostomy occlusion'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity932 :: ('MESH:D020300', 'Disease') :: ['Intracranial hemorrhage'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficit']
@entity432 :: (MESH:D001157,Disease) :: ['ventriculostomy occlusion']
