Three @entity5 @entity1 were treated with arterial infusion chemotherapy through the internal iliac artery. Two @entity1 with pelvic recurrences unresectable after APRA were treated with intensive chemotherapy and the other @entity1 with neoadjuvant chemotherapy. In all cases, @entity1487 (500 mg/ body/day) was administered continuously for 5 days or 14 days. We attempted three methods for this procedure which were a bilateral catheterization to the internal iliac artery, a single catheterization with an embolization to the other internal iliac artery and a single catheterization without the embolization. As the result of this treatment, in the resected specimen with neoadjuvant case, histological @entity39 was found in 50% in the main @entity5 and the metastatic lymph nodes. One @entity1 with pelvic recurrence showed a partial response in CT imaging, but died one year later of the recurrence around the external iliac artery. The other @entity1 with pelvic recurrence treated with the bilateral catheterization had no efficacy on CT imaging, but his @entity787 level has decreased at present. It was concluded that arterial infusion chemotherapy was effective for advanced @entity5 and the pelvic recurrences. However, the efficacy of this treatment is limited to the area to which the drugs are delivered. Thus, it is important that the method and the location of the catheterization are determined adequately for each case.

[Arterial infusion chemotherapy in pelvic space for advanced XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'rectal cancer'] @entity787 :: ('1084', 'Gene') :: ['CEA'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-FU']
@entity5 :: (MESH:D009369,Disease) :: ['rectal cancer']
