@entity1787 and @entity16425 are environmental pollutants especially present in smog. They are oxidants potent to cause @entity6587 , @entity82 , and @entity2415 . Other occupational hazards are mineral dust particles ( @entity1355 , @entity3440 ) which may cause the development of @entity32 and @entity82 in the lungs. Inflammatory cells (neutrophils, eosinophils, monocytes, macrophages) become activated during @entity32 and produce @entity224 anion radicals. Reactive @entity26 species developed e.g. in smog have been recognized--at least partly--to be responsible for the observed @entity3145 . Several mechanisms leading to @entity137 , including disbalance of vegetative nervous control, damage of bronchial epithelium, role of mediators of @entity32 and other issues are discussed. (Fig. 1, Ref. 32.)

[ XXXX radicals in the mechanism of lung injury caused by air pollutants].

@entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity82 :: ('MESH:D005355', 'Disease') :: ['lung fibrosis', 'fibrosis'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity3145 :: ('MESH:D017695', 'Disease') :: ['pulmonary tissue damage'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity2415 :: ('MESH:D004646', 'Disease') :: ['emphysema'] @entity3440 :: ('MESH:D012822', 'Chemical') :: ['silica'] @entity16425 :: ('MESH:D009589', 'Chemical') :: ['nitrogen oxides'] @entity6587 :: ('MESH:D016535', 'Disease') :: ['bronchial hyperreactivity'] @entity224 :: ('MESH:D013481', 'Chemical') :: ['superoxide'] @entity1787 :: ('MESH:D010126', 'Chemical') :: ['Ozone'] @entity1355 :: ('MESH:D001195', 'Disease') :: ['asbestos']
@entity26 :: (MESH:D010100,Chemical) :: ['Oxygen']
