BACKGROUND: To reduce the mortality associated to @entity1412 ( @entity1412 ), screening of close relatives of @entity1 with the disease is crucial. AIM: To analyze the results of the surgical treatment of @entity1 with @entity1412 , and to evaluate the family screening. @entity1 AND METHODS: Clinical records of @entity1 operated in our institution since 1977, were reviewed analyzing surgical and pathological results, and follow up. In their family members, we evaluated and analyzed the performance of screening tests, former surgeries, history of disease-related @entity5 and mortality, all due to @entity1412 . RESULTS: Between January 1977 and August 2002, 15 @entity1 were operated on. Of these, only 33% consulted on the setting of a familial screening. A proctocolectomy and terminal ileostomy was performed in 27% of @entity1 ; 20% had a proctocolectomy and ileal pouch, and 53% underwent a total colectomy with ileo-rectal anastomosis. Morbidity and mortality were 7% and 0%, respectively. Twenty percent had a @entity14 . During a median of 68 months follow-up, the disease-related survival was 92%; no @entity5 of the rectal stump was detected. Of the 122 family members identified, only 33% with clear indication of screening underwent a colonoscopy. Twenty-nine percent had a confirmed @entity1412 and were operated: in 61% of them a @entity14 was found, and 91% of these died. CONCLUSIONS: The results of the surgical treatment of @entity1412 are satisfactory. Nevertheless, family screening should be improved to reduce the high rates of mortality revealed in the study of other family members.

[Treatment of XXXX and family screening].

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity1412 :: ('MESH:D011125', 'Disease') :: ['Familial Adenomatous Polyposis', 'FAP'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer']
@entity1412 :: (MESH:D011125,Disease) :: ['Familial Adenomatous Polyposis']
