PURPOSE OF REVIEW: With the growing prevalence of dysglycemia, the increased frequency of hospitalizations in @entity6 @entity1 , and the notable effects of acute stress on @entity413 metabolism, it is not surprising that @entity4854 is frequently encountered in the inpatient setting. @entity4854 is associated with increased morbidity and mortality, as well as increased length of stay and costs. Accordingly, there has been intense interest in the optimal management of @entity413 levels in hospitalized @entity1 . However, overly stringent control may result in @entity4053 , which in itself is a risk factor for adverse clinical outcome. A fine balance in management is obviously important. RECENT FINDINGS: We herein review recent observational studies and randomized clinical trials regarding glycemic management in the hospital, both in the critical care and noncritical care settings. Though results are conflicting, a consensus has recently emerged that although @entity413 control is important, prior recommendations had become too aggressive. SUMMARY: Newly updated national guidelines call for a blood @entity413 target for critically ill @entity1 of 140-180 mg/dl, using a continuous insulin infusion if needed. In the noncritically ill, a value less than 140 mg/dl before meals and less than 180 on random checks is recommended. A regimen of basal insulin in conjunction with premeal and supplemental insulin is preferred, as opposed to simple sliding scale insulin. Importantly, these guidelines are merely recommendations and management of the @entity1602 inpatient must be tailored to suit the individual, considering their other comorbidities, risk factors for @entity4053 , availability and training of hospital staff, and overall prognosis.

Hospital management of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity4053 :: ('MESH:D007003', 'Disease') :: ['hypoglycemia'] @entity1602 :: ('MESH:D006944', 'Disease') :: ['hyperglycemic'] @entity4854 :: ('MESH:D006943', 'Disease') :: ['hyperglycemia', 'Hospital hyperglycemia'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity4854 :: (MESH:D006943,Disease) :: ['hyperglycemia']
