OBJECTIVE: Several national and international scoring systems are used to diagnose @entity3949 (PNP). The variety in these scores and the lack of data on validity and predictive value has led to a comparison and validation of the scores with clinical standards for PNP to determine the most powerful measurement for screening. RESEARCH DESIGN AND METHODS: Three matched groups were selected: 24 @entity6 @entity1 with @entity1411 , 24 @entity6 @entity1 without PNP or @entity1066 , and 21 control subjects without @entity6 . In all @entity1 the scores from the International Consensus on the @entity6 (ICDF) and the Dutch Nederlandse @entity6 Federatie-Centraal Beleids Orgaan ( @entity6536 /CBO) were tested. The @entity3949 Symptom score, the @entity3949 Examination score, Heart Rate Variability, the Nerve Conduction Sum score, and a San Antonio Consensus sum score were obtained as clinical standards. Reproducibility was tested in a separate study (13 @entity1 ). RESULTS: The construct validity and discriminative power of the ICDF and @entity6536 /CBO scores were comparable, although monofilaments ( @entity6536 /CBO) scored lower. The predictive value was good for all scores, with the best results being obtained for the tuning fork ( @entity6536 /CBO). Reproducibility of the @entity6536 /CBO scores (monofilaments and tuning fork) was high. CONCLUSIONS: The characteristics of the scores of tests recommended by ICDF and @entity6536 /CBO are comparable. The single use of the 128-Hz tuning fork produces results similar to the extended scores of the ICDF and much better than those of monofilaments on validation and for predictive value. For screening we therefore advise the use of the tuning fork alone.

Back to basics in diagnosing XXXX with the tuning fork!

@entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetic', 'diabetes', 'Diabetic Foot'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcers'] @entity3949 :: ('MESH:D003929', 'Disease') :: ['Diabetic Neuropathy', 'diabetic polyneuropathy'] @entity1411 :: ('MESH:D016523', 'Disease') :: ['neuropathic foot ulcers'] @entity6536 :: ('3084', 'Gene') :: ['NDF']
@entity3949 :: (MESH:D003929,Disease) :: ['diabetic polyneuropathy']
