INTRODUCTION: @entity21159 ( @entity21159 ) is a rare disorder involving the lumen of the @entity825 -bronchial tree and characterized by @entity33 in the @entity825 and bronchus, sparing the posterior wall. We here report two cases of @entity1 with @entity21159 osteochondroplastica and review the relevant literature briefly. CASE PRESENTATION: Case 1 was a 64-year-old @entity1 with a history of @entity1030 ( @entity1030 ) who presented with frequent non-productive cough for 2 years. Chest computed tomography (CT) showed signs consistent with @entity1030 and evident irregular narrowing of the tracheal and both main bronchial lumen caused by @entity730 foci. Fibre optic bronchoscope (FOB) was performed and showed dozens of sub-mucosal nodules protruding into the lumen of lower half of the @entity825 and both main bronchi. Histopathological exam demonstrated @entity33 and cartilage in the sample. Her follow-up has been uneventful for 3 years. Case 2 was a 37-year-old @entity1 presented with hoarseness, exertional @entity1353 , and intermittent dry cough for about 3 years. Chest CT scans showed irregular nodules around the entire circumference of the @entity825 extending from sub-glottic region to lower @entity825 . FOB showed @entity850 and diffused sub-mucosal calcified nodules protruding from the antero-lateral portion of the @entity825 in the subglottic region. Over the following 12 months, his disease is stable. CONCLUSIONS: @entity21159 is a rare, benign disease with slow progression, clinicians should be aware of @entity21159 and should consider it in @entity1 with chronic cough, recurrent @entity1729 and evolving exertional @entity1353 .

XXXX : two cases and a review of the literature.

@entity825 :: ('MESH:D055090', 'Disease') :: ['trachea'] @entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'man'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity33 :: ('MESH:D052016', 'Disease') :: ['sub-mucosal ossification', 'multiple sub-mucosal osseous and cartilaginous nodules'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcific'] @entity21159 :: ('MESH:C536977', 'Disease') :: ['tracheobronchopathia', 'TO', 'Tracheobronchopathia osteochondroplastica'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['respiratory infection'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['Chronic Obstructive Pulmonary Disease', 'COPD'] @entity850 :: ('MESH:D003251', 'Disease') :: ['glottic stenosis']
@entity21159 :: (MESH:C536977,Disease) :: ['Tracheobronchopathia osteochondroplastica']
