Objective. To evaluate the efficacy and safety of Rhubarb supplementation in @entity1 of @entity740 . Material and Methods. This study was a prospective comparative study conducted in @entity1 of @entity740 (stages 3 _ 4) attending Renal Clinic of Department of Medicine, JN Medical College _ Hospital, AMU, Aligarh. @entity1 were randomly divided into two interventional groups. Group I (Control) was given conservative management while Group II (Rhubarb) received conservative management along with Rhubarb capsule (350   mg, thrice daily) for 12 weeks. Haemogram and renal function tests were measured at 0, 4, 8, and 12 weeks of treatment. Results. There was progressive improvement in clinical features in both the groups after 12 weeks of treatment but Rhubarb group showed more marked improvement as compared to control group. Both groups showed gradual improvement in the biochemical parameters as compared to their pretreated values which was more marked in Rhubarb supplemented group. There was reduction in blood @entity413 , blood @entity1133 , serum @entity1011 , and 24 hour total urine protein (TUP). There was increase in haemoglobin, 24 hour total urine volume (TUV), and glomerular filtration rate (GFR). There was no statistical difference in two groups with respect to side effects (P > 0.05). Conclusion. Rhubarb supplementation improved the therapeutic effect of conservative management in stage 3 and stage 4 @entity1 of @entity740 .

Evaluation of Rhubarb Supplementation in Stages 3 and 4 of XXXX : A Randomized Clinical Trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1133 :: ('MESH:D014508', 'Chemical') :: ['urea'] @entity740 :: ('MESH:D051436', 'Disease') :: ['chronic kidney disease'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity740 :: (MESH:D051436,Disease) :: ['Chronic Kidney Disease']
