OBJECTIVE: To compare @entity1 with @entity195 ( @entity195 ) and @entity191 ( @entity191 ) with regard to their awareness of @entity73 , self-care, and motor-related @entity51 . BACKGROUND: Unawareness of deficits, a clinically important symptom, is found in @entity195 . It has been hypothesized to be associated with @entity952 but has been little studied in other @entity179 . Because @entity191 has a different anatomic-pathologic substrate, a comparison of impairment of awareness in @entity195 and @entity191 may shed light on the neural basis of this phenomenon. METHOD: Impairment of awareness was measured as the difference between @entity1 self-report and caregiver ratings of @entity1 abilities on questionnaires tapping @entity73 , self-care, and motor function. These "discrepancy scores" were then compared between the two diagnostic groups and examined in relation to selected neuropsychological test data. RESULTS: In general, both @entity195 and @entity191 @entity1 rate themselves as being less impaired than do their caregivers. The two diagnostic groups, @entity195 and @entity191 , differ significantly, however, on awareness discrepancy measures in the cognitive domain. In their ratings of @entity1 cognitive skills, @entity195 caregivers rate @entity1 as significantly more impaired than @entity1 rate themselves, whereas @entity191 caregivers and @entity1 do not differ significantly on these ratings. Impaired awareness in @entity191 but not in @entity195 is associated with poorer overall cognitive function and performance on tests measuring memory, attention, and constructional ability. CONCLUSIONS: Both @entity195 and @entity191 @entity1 display @entity73 in multiple domains, including motor-related neurologic function. @entity191 @entity1 with comparatively intact cognitive function display relatively preserved @entity51 .

Clinical and neuropsychological correlates of XXXX in @entity195 and @entity191 : a comparative study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impaired awareness of deficits', 'cognitive, emotional/social interaction'] @entity191 :: ('MESH:D010300', 'Disease') :: ['Parkinson disease', 'PD'] @entity51 :: ('MESH:D009461', 'Disease') :: ['awareness of motor and other deficits', 'neurologic deficits'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative disorders'] @entity952 :: ('MESH:D019958', 'Disease') :: ['disruption of frontal-subcortical circuits'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', 'Alzheimer disease']
@entity73 :: (MESH:D003072,Disease) :: ['impaired awareness of deficits']
