BACKGROUND: The purpose of this study was to explore the potential risk factors associated with the failure of an upper extremity replantation with a focus on cigarette or @entity286 use. @entity1 AND METHODS: A cohort of 102 @entity1 with 149 replants (6 extremities, 143 digits) and a mean age of 41 years (range 5 to 72 years) was enrolled in this study. The data collected included age, gender, @entity286 /cigarettes use, @entity130 mechanism, underlying disease (e.g., @entity101 ( @entity101 ), @entity6 ( @entity6 ), etc.), and vein graft use. An analysis with a multivariable regression was conducted to identify the risk factors of replant failure and their respective odds ratios (ORs). RESULTS: Multilevel generalized linear mixed models (GLMMs) with a binomial distribution and logit link showed that smoking did not increase the risk of replant failure (p = 0.234). In addition, the survival of replants was not affected by @entity6 or @entity101 (p = 0.285 and 0.938, respectively). However, the replantation results were significantly affected by the age of the @entity1 and the mechanism of injury. @entity1 older than 50 years and those with @entity155 or @entity130 tended to have a higher risk of replant failure (OR = 2.29, 6.45, and 5.42, respectively; p = 0.047, 0.028, and 0.032, respectively). CONCLUSIONS: This study showed that the use of cigarettes/ @entity286 did not affect the replantation outcome. The main risks for replant failure included being older than 50 years and the @entity130 mechanism ( @entity155 or @entity130 ).

The Risk Factors for Failure of an Upper Extremity Replantation: Is the Use of Cigarettes/ XXXX a Significant Factor?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'HTN'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus', 'DM'] @entity155 :: ('MESH:D014084', 'Disease') :: ['avulsion'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma', 'crush injuries']
@entity286 :: (4097,Species) :: ['Tobacco']
