PURPOSE: To evaluate the anterior keratoprosthesis-cornea interface in eyes with @entity20917 keratoprosthesis (Kpro). METHODS: In a prospective non-interventional study, @entity1 with @entity20917 Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images were used to measure and describe characteristics of the anterior keratoprosthesis-cornea interface, epithelial interaction at the keratoprosthesis edge and the keratoprosthesis-cornea interface gap. RESULTS: Ten @entity1 including 4 male and 6 female subjects with different preoperative diagnoses, i.e. 8 multiple corneal graft failures and 2 immunological ocular surface diseases, were studied. Mean age was 62.1    20.0 (range, 33.0-83.0) years and mean interval between surgery and UHR-OCT evaluation was 15.2    11.09 months. In eight @entity1 , 360   epithelial growth over the peripheral edge of the Kpro was documented. We detected keratoprosthesis-cornea interface gap in three @entity1 . One subject had developed @entity86 8 months after surgery and the other two cases were among the high risk group according to the preoperative diagnosis. In one @entity1 with severe @entity8814 , the Kpro edge was inserted into the anterior stroma and covered with epithelium. CONCLUSION: UHR-OCT showed that corneal epithelium covers the Kpro edge and seals the potential space between the Kpro and cornea in 80% of cases. The presence of a gap in the interface and lack of epithelial sealing around the Kpro edge might be associated with @entity3225 .

Ultra high resolution optical coherence tomography in XXXX keratoprosthesis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity8814 :: ('MESH:D015814', 'Disease') :: ['ocular hypotony'] @entity20917 :: ('MESH:C565753', 'Disease') :: ['Boston type I'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative endophthalmitis'] @entity3225 :: ('MESH:D009877', 'Disease') :: ['endophthalmitis']
@entity20917 :: (MESH:C565753,Disease) :: ['Boston type I']
