BACKGROUND: The @entity1600 ( @entity1600 ) is the first lymph node in the regional nodal basin to receive metastatic cells. In-transit nodes are found between the primary @entity320 site and regional nodal basins. To date, this is one of the first reports on micrometastasis to in-transit nodes. METHODS: Retrospective database and medical records were reviewed from October 21, 1993, to November 19. 1999. At the UCSF @entity320 Center, @entity1 with @entity5 thickness > 1 mm or < 1 mm with high-risk features are managed with preoperative lymphoscintigraphy, selective @entity1600 dissection, and wide local excision. RESULTS: Thirty (5%) out of 557 extremity and truncal @entity320 @entity1 had in-transit SLNs. Three @entity1 had positive in-transit SLNs and negative SLNs in the regional nodal basin. Two @entity1 had positive in-transit and regional SLNs. Three @entity1 had negative in-transit SLNs but positive regional SLNs. The remaining 22 @entity1 were negative for in-transit and regional SLNs. CONCLUSIONS: In-transit SLNs may harbor micrometastasis. About 10% of the time, micrometastasis may involve the in-transit and not the regional @entity1600 . Therefore, both in-transit and regional SLNs should be harvested.

Micrometastasis to in-transit lymph nodes from extremity and truncal XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['sentinel lymph node', 'SLN'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma', 'Melanoma']
@entity320 :: (MESH:D008545,Disease) :: ['malignant melanoma']
