Twenty-eight @entity1 with wide spectrum organ involvement of progressive @entity785 but without signs or symptoms suggestive of @entity299 were studied by non-invasive cardiac techniques. The 12-lead electrocardiogram showed abnormalities in 6 @entity1 : one had abnormal T waves and 5 had complete or incomplete @entity714 . Twenty-four hour ambulatory electrocardiography demonstrated higher average heart rates than in similar aged controls (82 +/- 9 vs 74 +/- 9 beats/min, P less than 0.05). In one @entity1 a short run of @entity1165 was recorded. No other significant @entity943 was documented. Echocardiographic measurements were within normal ranges but small pericardial effusions were observed in two @entity1 (7%). Resting first pass radionuclide angiography, utilizing 12 mCi of @entity1136 99m were performed in 23 @entity1 . Seven @entity1 (30%) had abnormal wall motion ( @entity2845 ), with a significant decrease in ejection fraction in comparison to those with normal wall motion (44 +/- 6% vs 60 +/- 6% P less than 0.01). Those with abnormal wall motion had suffered the disease longer than those with normal wall motion (13 +/- 4 vs 9.5 +/- 7 y). In conclusion, the heart is involved in half of the @entity1 in this series; non-invasive cardiac assessment is useful in disclosing the early @entity299 and may influence long-term management.

Non-invasive assessment of early @entity299 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1136 :: ('MESH:D013667', 'Chemical') :: ['technetium'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachycardia'] @entity714 :: ('MESH:D002037', 'Disease') :: ['right bundle branch block'] @entity2845 :: ('MESH:D018476', 'Disease') :: ['diffuse hypokinesia'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac involvement'] @entity943 :: ('MESH:D001145', 'Disease') :: ['arrhythmia'] @entity785 :: ('MESH:D012595', 'Disease') :: ['systemic sclerosis']
@entity785 :: (MESH:D012595,Disease) :: ['systemic sclerosis']
