BACKGROUND: @entity2023 is one of the most common @entity102 in @entity1 . Although it has a large impact on the @entity1 's quality of life, little is known about the factors associated with its severity. The aim of this study was to assess the factors associated with the severity of @entity7370 among @entity1 in the general population. METHODS: A survey was conducted using an online research panel in 2012. Parents were asked to answer an International Study of @entity566 in Childhood-based questionnaire to identify @entity1 with current @entity7370 and evaluate factors associated with the severity of its symptoms. Severity was rated according to the degree of impairment caused by the symptoms in the @entity1 's daily life. RESULTS: Among 26,725 @entity1 aged 6-12 years old, @entity7370 was defined in 5175 (19.4%), and of these, 688 @entity1 (13.3% of @entity1 with current @entity7370 ) presented severe symptoms. Living in areas with a high cedar and cypress pollen count and having concurrent @entity484 were associated with severe @entity7370 [adjusted OR (95% CI): 1.21 (1.00-1.46) and 1.45 (1.20-1.75), respectively]. Further, a maternal history of @entity565 and @entity2023 was a significant risk factor for severe @entity7370 [1.34 (1.04-1.74) and 1.30 (1.10-1.53), respectively]. However, living with fur-bearing animals (pets) before 1 year of age proved to be a protective factor against severe @entity7370 [0.70 (0.52-0.94)]. CONCLUSIONS: Environmental factors such as pets and pollen, together with comorbidities and a maternal history of @entity56 , play an important role in determining the severity of @entity7370 .

Factors associated with the severity of childhood XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patient'] @entity7370 :: ('OMIM:613207', 'Disease') :: ['rhinoconjunctivitis'] @entity2023 :: ('MESH:D006255', 'Disease') :: ['Allergic rhinitis', 'allergic rhinitis'] @entity566 :: ('MESH:D006967', 'Disease') :: ['Asthma and Allergies'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic diseases'] @entity56 :: ('MESH:D004342', 'Disease') :: ['allergic diseases'] @entity484 :: ('MESH:D004485', 'Disease') :: ['eczema']
@entity7370 :: (OMIM:613207,Disease) :: ['rhinoconjunctivitis']
