BACKGROUND: Sleep disordered @entity1353 (SDB) is associated with @entity1155 (hereafter "vigilance") in clinical settings, but this association has yet to be confirmed in the general population. The aim of this study is to determine the associations between SDB and vigilance in a large sample of community-based @entity1 . METHODS: The study sample consisted of 1508 community-dwelling Japanese @entity1 (age: 30-79 years, @entity1 : 62.7%, mean body mass index [BMI]: 23.1  kg/m(2)). Vigilance was measured by the psychomotor vigilance task (PVT), and SDB was measured by overnight pulse oximetry. We investigated odds ratios for "high mean @entity137 ( @entity137 )" and "high number of lapses," which we defined as the 75th percentile of each value, across categories of oximetry values (three percent @entity26 desaturation index [ODI], 4% ODI, average @entity26 saturation, minimum @entity26 saturation). RESULTS: Multivariable-adjusted odds ratios of high mean @entity137 and high number of lapses in severe SDB (3% ODI  >=   30.0 events/h) were 3.0 (95% confidence interval: 1.0-8.9; P for trend  =  0.03) and 3.3 (95% confidence interval: 1.2-9.2, P for trend  =  0.03), respectively, compared to @entity1 without SDB. Similar associations were observed between PVT metrics and four percent ODI. No significant associations between average @entity26 saturation and PVT metrics were observed. Minimum @entity26 saturation was significantly associated with the trend of high number of lapses (P for trend  =  0.007), but not with high mean @entity137 . CONCLUSIONS: The present study provides evidence that the intermittent @entity519 in SDB is significantly associated with the deterioration of PVT outcome metrics.

Sleep-related intermittent @entity519 is associated with XXXX in Japanese community residents.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'persons'] @entity137 :: ('MESH:D064420', 'Disease') :: ['reaction time', 'RT'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['breathing'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity519 :: ('MESH:D000860', 'Disease') :: ['hypoxia'] @entity1155 :: ('MESH:D011596', 'Disease') :: ['decreased psychomotor vigilance']
@entity1155 :: (MESH:D011596,Disease) :: ['decreased psychomotor vigilance']
