UNASSIGNED: OBJECTIVE @entity816 ( @entity816 ) are common @entity1313 in @entity1 . Optimal management of PA is gross-total resection (GTR), after which event-free survival (EFS) is excellent. The tempo of recurrences, when they do occur, is relatively sparsely reported, and there is no agreed upon surveillance recommendation for @entity1 in this category. It has been suggested that surveillance MRI is performed too frequently and could be safely reduced in both frequency and duration. The authors conducted a retrospective review of pediatric @entity1 with PA who underwent GTR at a single institution over an 18-year period and who had documented recurrences. METHODS All @entity1 under 18 years of age who had undergone GTR of a PA between 1996 and 2013 were included in the study. Clinical, radiological, and @entity5 characteristics were recorded. RESULTS Sixty-seven @entity1 met the criteria for GTR over the period studied. The 5-year EFS rate was 95% (95% CI 89%-100%) and overall survival was 100%. Recurrences showed a nonsignificant trend of occurring more commonly in @entity1 with persistent nonenhancing @entity854 after surgery, but there was no difference with regard to @entity5 location. All recurrences occurred before 3 years postresection, all were asymptomatic, and all @entity1 were observed for at least one additional scan after the initial detection during routine surveillance MRI before further therapy was undertaken. CONCLUSIONS EFS and overall survival are excellent after GTR in this population with @entity816 . Progression after recurrence occurs slowly and is asymptomatic. A less intensive schedule of MRI surveillance in this group of @entity1 would result in time and cost savings, without compromising safety. The authors suggest a schedule of 6 MRI scans to be obtained postoperatively, at 3-6 months, then at 1, 2, 3.5, and 5 years.

Low rates of recurrence and slow progression of pediatric XXXX after gross-total resection: justification for reducing surveillance imaging.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['brain tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity854 :: ('MESH:D018376', 'Disease') :: ['FLAIR abnormalities'] @entity816 :: ('MESH:D001254', 'Disease') :: ['Pilocytic astrocytomas', 'PAs']
@entity816 :: (MESH:D001254,Disease) :: ['pilocytic astrocytoma']
