PURPOSE: The atrial transseptal procedure is used in catheter ablation of left-sided @entity943 . Studies in adult @entity1 have shown the SafeSept    transseptal guidewire (SSTG) to be effective in atrial transseptal procedures. We analyzed our 5-year experience with SSTG use in @entity299 @entity1 undergoing catheter ablation. METHODS: This is a single-center retrospective analysis of @entity1 undergoing catheter ablation from 2009 to 2014. We identified all procedures where SSTG was used for atrial transseptal or trans-baffle access. Success of transseptal access and complications were recorded and compared to the standard transseptal approach without the SSTG. RESULTS: One hundred twenty-seven @entity1 underwent 132 attempted atrial transseptal or trans-baffle procedures using SSTG. Median age was 14 (1.2-38)   years. @entity943 substrates included @entity713 reentrant @entity591 (90.2%), @entity591 (4.5%), @entity1165 (2.3%), and @entity2917 reentrant @entity591 (2.3%). Transseptal or trans-baffle access was successful in 96.2% of the SSTG cases compared to 98.9% in the standard transseptal group without SSTG (p   =   NS). The youngest @entity1 with successful atrial transseptal procedure using SSTG was 4  years old. SSTG was used to successfully cross a surgically created atrial baffle in a @entity1 who had undergone the Mustard procedure. There was one major complication in both groups, 0.8% in the SSTG group compared to the standard transseptal group without SSTG, 1.1% (p   =   NS). The major complication in the SSTG group occurred when the SSTG crossed the aorta into the coronary artery system and mimicked placement in the left atrial appendage, with subsequent placement of a transseptal sheath into the aorta, requiring sternotomy and surgical intervention. CONCLUSIONS: SSTG is effective for use in atrial transseptal and surgical trans-baffle access in @entity299 @entity1 . Placement of the SSTG into the pulmonary vein is necessary to avoid major complications, and if not achieved requires additional methods to determine appropriate left atrial placement.

Utility and safety of the SafeSept    transseptal guidewire for electrophysiology studies with catheter ablation in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2917 :: ('MESH:D013611', 'Disease') :: ['AV nodal'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachycardia'] @entity713 :: ('MESH:D054537', 'Disease') :: ['AV'] @entity591 :: ('MESH:D013610', 'Disease') :: ['tachycardia', 'atrial tachycardia'] @entity299 :: ('MESH:D006331', 'Disease') :: ['pediatric and congenital heart disease'] @entity943 :: ('MESH:D001145', 'Disease') :: ['Arrhythmia', 'arrhythmias']
@entity299 :: (MESH:D006331,Disease) :: ['pediatric and congenital heart disease']
