BACKGROUND: The aim of this study was to evaluate the prognostic value of continuous electroencephalogram (cEEG) during the first 48  h following @entity1167 ( @entity1167 ) in @entity1 treated with targeted temperature management (TTM). METHODS: We reviewed data from 92 comatose post- @entity1167 @entity1 over a 6  year-period; cEEG recordings were performed during TTM and restoration of normothermia. EEG findings were divided into four time-periods: 0-8, 8-16, 16-24, and 24-48  h after @entity1167 . Background EEG findings were defined as moderate @entity75 (diffuse slowing with reactivity/variability), severe @entity75 (diffuse slowing without reactivity/variability), burst suppression or suppression, and dichotomized as malignant (suppression/burst suppression/severe @entity75 ) or benign (moderate @entity75 ). @entity302 was defined as the presence of @entity410 , @entity302 , or periodic discharges. Neurological outcome was assessed at 3  months using the cerebral performance categories (CPC) score (good outcome: CPC 1-2). RESULTS: 26/92 (28  %) @entity1 had a good outcome. Malignant patterns were associated with a poor outcome at all time-points, with a high positive predictive value (94-97  %) but a poor negative predictive value (44-56  %). @entity302 did not influence the prognostic value of EEG patterns. All @entity1 with moderate @entity75 and @entity410 or generalized periodic discharges had a poor outcome. CONCLUSIONS: cEEG can identify @entity1 with poor outcome from the first hours following @entity1167 , with limited predictive value for good outcome. @entity302 did not improve the prognostic accuracy of EEG, but @entity410 and generalized periodic discharges were associated with poor outcome even when developing on a benign EEG pattern.

The Prognostic Value of 48-h Continuous EEG During Therapeutic Hypothermia After XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity75 :: ('MESH:D001927', 'Disease') :: ['encephalopathy'] @entity302 :: ('MESH:D004827', 'Disease') :: ['Epileptiform activity', 'sporadic epileptiform discharges'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['cardiac arrest', 'CA']
@entity1167 :: (MESH:D006323,Disease) :: ['Cardiac Arrest']
