PURPOSE: To clarify the antimicrobial efficacy of @entity26410 ( @entity21482 ) and @entity4410 ( @entity4411 ) by testing their impact on the growth of seven bacterial strains known to be involved in the pathophysiology of both peri-implant disease and halitosis- @entity794 , @entity6586 , @entity2523 , @entity3288 , @entity8209 , @entity14148 , and @entity3289 . MATERIALS AND METHODS: A time-response growth curve was obtained. Commercial mouthrinses with @entity4411 , @entity21482 , or both were added to the media in a final concentration of 0.25% @entity4411 , 2.5% @entity21482 , and 2.5% @entity21482 with 0.25% @entity4411 . RESULTS: Both @entity4411 and @entity21482 effectively inhibited the growth of almost all bacterial strains tested except @entity14148 . @entity21482 was generally more effective in suppressing bacterial growth than @entity4411 . @entity21482 with @entity4411 showed the greatest inhibitory activities on almost all strains of bacterial growth except for @entity2523 and @entity14148 , followed by @entity21482 , then @entity4411 , thus suggesting the possibility of a synergistic effect of the two agents. @entity2523 exhibited a different pattern because @entity21482 showed the most significant inhibitory effect. @entity4411 did not show growth inhibitory effects on @entity14148 , but @entity21482 did. CONCLUSION: @entity219 and @entity4411 effectively inhibit bacterial growth that causes both @entity737 . The effect is even more powerful when applied in combination.

Antimicrobial Effectiveness of @entity4410 and @entity26410 -Containing Mouthrinses on Bacteria of XXXX .

@entity6586 :: ('1309', 'Species') :: ['Streptococcus mutans'] @entity8209 :: ('851', 'Species') :: ['Fusobacterium nucleatum'] @entity14148 :: ('158', 'Species') :: ['Treponema denticola', 'T denticola'] @entity219 :: ('MESH:D015032', 'Chemical') :: ['Zinc'] @entity794 :: ('1280', 'Species') :: ['Staphylococcus aureus'] @entity3288 :: ('28131', 'Species') :: ['Prevotella intermedia'] @entity21482 :: ('CHEBI:49976', 'Chemical') :: ['ZnCl2'] @entity737 :: ('MESH:D057873', 'Disease') :: ['halitosis and peri-implant disease'] @entity3289 :: ('28112', 'Species') :: ['Tannerella forsythia'] @entity4411 :: ('MESH:C015101', 'Chemical') :: ['CPC'] @entity4410 :: ('MESH:D002594', 'Chemical') :: ['cetylpyridinium chloride'] @entity26410 :: ('MESH:C016837', 'Chemical') :: ['zinc chloride'] @entity2523 :: ('837', 'Species') :: ['P gingivalis', 'Porphyromonas gingivalis']
@entity737 :: (MESH:D057873,Disease) :: ['Halitosis and Peri-implant Disease']
