OBJECTIVE: To study the relationship of @entity1534 , lower esophageal sphincter pressure and @entity8243 in @entity354 , to evaluate the effect of @entity1534 on @entity354 . METHODS: 20 @entity1 were underwent 24-hour ambulatory esophageal pH monitoring to confirm the diagnosis of @entity354 , and their lower esophageal sphincter pressure was measured by esophageal manometry. The @entity1 were diagnosed endoscope negative @entity354 and endoscope positive @entity354 by endoscopy, and 3 biopsy specimens obtained from the gastric antrum at the same time were used for @entity1534 culture, rapid urease test and Warthin-Starry stain. @entity281 was affirmed when at least two of the three tests were positive, then the @entity1 were divided into Hp-negative group and Hp-positive group. Fasting serum @entity8243 concentration was determined by radioimmunoassay in 13 @entity1 . RESULTS: Hp-positive @entity1 were 8 (male 4, endoscope negative @entity354 2, mean age 55 +/- 9), Hp-negative @entity1 were 12 (male 10, endoscope negative @entity354 3, mean age 55 +/- 10). 13 of these @entity1 were performed fasting serum @entity8243 measurement. The mean lower esophageal sphincter pressure, @entity8243 concentration and 24-hour pH monitoring DeMeester score in Hp-positive @entity1 group were 11.25 mm Hg, 87.437 pg/ml and 72.30 respectively, and those in Hp-negative @entity1 group were 13.75 mm Hg, 88.725 pg/ml and 55.64. Between the two groups, there was no significant difference in LESP, @entity8243 and DeMeester score (P = 0.193, P = 0.932 and P = 0.479); There was no correlation between LESP and @entity8243 , while serum @entity8243 level is associated strongly with DeMeester score (r = 0.902, P < 0.01). CONCLUSION: The study showed that @entity1534 had no effect on LESP by @entity8243 , however serum fasting @entity8243 concentration and DeMeester score were associated with each other.

[A study on the relationship of XXXX , @entity8243 and @entity354 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Hp infection'] @entity8243 :: ('2520', 'Gene') :: ['gastrin'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux disease', 'GERD'] @entity1534 :: ('210', 'Species') :: ['Helicobacter pylori']
@entity1534 :: (210,Species) :: ['Helicobacter pylori']
