We compared peripheral nerve fibers and muscle fibers in @entity3918 ( @entity3918 ) using a computer-assisted device for morphometry. In the 17 cases with @entity3918 studied, the sural nerves of 14 cases (82%) showed various degrees of @entity17 (MSA) per endoneurial area. Of these, 8 cases (47%) presented with a mild @entity17 , 5 cases (29.4%) with moderate reduction, and one case (6%) with severe reduction. The number of myelinated nerve fibers was not significantly reduced in @entity3918 when compared with control nerves, due to clusters of small regenerated nerve fibers. The mean diameter of the muscle fibers in 6 of the 17 cases was less than 40 microm. Of these 6 severely affected cases, 5 revealed a considerable @entity17 . Other cases, which appeared to be normal in respect to the diameter of muscle fibers, showed various degrees of @entity17 . Thus, there is usually, but not always a morphometric correlation of the severity of changes between peripheral nerves and muscle. The severity of the @entity1897 appears to depend largely on the @entity1 's age, the stage of the disorder, and the time of progression. Electron microscopic examination of sural nerves showed significant, though non-specific pathological changes.

Comparative morphometric evaluation of peripheral nerves and muscle fibers in XXXX .

@entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral neuropathy'] @entity3918 :: ('MESH:D009223', 'Disease') :: ['myotonic dystrophy', 'MD'] @entity17 :: ('MESH:D003711', 'Disease') :: ['reduction of the MSA', 'reduction of the myelin sheath area'] @entity1 :: ('9606', 'Species') :: ['patient']
@entity3918 :: (MESH:D009223,Disease) :: ['myotonic dystrophy']
