BACKGROUND/AIM: Mediastinoscopy is an invasive procedure that is used in the diagnosis of @entity3629 and in staging @entity2 . @entity5 cell seeding during mediastinoscopy along the mediastinum and the incision line is a very rare complication. This study aimed to test the safety of mediastinoscopy in terms of @entity5 seeding by cytological evaluation of mediastinal lavage samples taken before and after biopsy. MATERIALS AND METHODS: The @entity1 who underwent mediastinoscopy in our hospital between 2011 and 2014 were studied prospectively. Seventy-three @entity1 with a diagnosis of lung or mediastinal @entity5 were included in the study. All @entity1 underwent classical cervical mediastinoscopy and mediastinal lavages were taken before and after the biopsy. Both lavage samples were sent to the pathology department in syringes for malignant cell cytology screening. RESULTS: The results of the histopathological examinations of lymph node biopsies were reactive in 25 @entity1 and positive for @entity5 in 48 @entity1 . In 2 of 48 @entity1 whose lymph nodes were reported to be positive for @entity5 , the mediastinal lavage sample was reported to be positive for @entity5 after biopsy, although it was negative preoperatively. In two @entity1 , both the pre- and postbiopsy lavage samples were reported to be positive for @entity5 . CONCLUSION: While performing dissection and biopsy during mediastinoscopy, @entity5 seeding into the mediastinum may occur. Long follow-up periods and large @entity1 series are needed to determine how cytopathological examination of both fluids would affect the prognosis.

The risk of XXXX cell dissemination in mediastinoscopy: a cytological study.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumor', 'malignancy'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity3629 :: ('MESH:D008477', 'Disease') :: ['mediastinal diseases']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
