BACKGROUND: @entity1 with @entity326 are at increased risk of @entity296 . However, the left ventricular ejection fraction (EF) typically remains preserved in @entity326 . Strain measurement using speckle-tracking echocardiography may quantify abnormalities in myocardial function not detected by conventional echocardiography. To investigate whether @entity326 results in greater strain changes than @entity295 alone, we evaluated strain in @entity1 with @entity295 and @entity326 . METHODS: We prospectively identified 35 @entity1 with @entity326 and 15 with @entity295 . These @entity1 underwent serial transthoracic echocardiograms at enrollment and 24 hours later. Measurements included longitudinal, radial, and circumferential strain in addition to standard echocardiographic assessments of left ventricular function. RESULTS: Longitudinal strain worsened significantly over 24 hours in @entity1 with @entity326 (P < 0.0001) but did not change in @entity1 with @entity295 alone (P = 0.43). No significant changes in radial or circumferential strain or EF were observed in either group over the 24-hour measurement period. In @entity1 with @entity326 , the significant worsening in @entity6475 persisted after adjustment for left ventricular end-diastolic volume and vasopressor use (P < 0.0001). In @entity1 with @entity295 , adjustment for left ventricular end-diastolic volume and vasopressor use did not alter the finding of no significant differences in @entity6475 (P = 0.48) or EF (P = 0.96). CONCLUSIONS: In @entity1 with @entity326 , but not @entity295 , @entity296 imaging using speckle-tracking echocardiography identified @entity296 in the absence of changes in EF. These data suggest that strain imaging may play a role in cardiovascular assessment during @entity326 .

Detection of XXXX in Septic Shock: A Speckle-Tracking Echocardiography Study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial strain', 'myocardial dysfunction'] @entity326 :: ('MESH:D012772', 'Disease') :: ['septic shock'] @entity6475 :: ('MESH:D013180', 'Disease') :: ['longitudinal strain']
@entity296 :: (MESH:D009202,Disease) :: ['Myocardial Dysfunction']
