Biotransformation of fluorotelomer (FT) compounds, such as 8:2 FT alcohol (FTOH) is now recognized to be a source of @entity2206 ( @entity2207 ) as well as other perfluoroalkyl acids. In this study, microbially mediated hydrolysis of FT industrial intermediates 8:2 FT acrylate (8:2 FTAC) and 8:2 FT @entity11379 (8:2 FTMAC) was evaluated in aerobic soils for up to 105d. At designated times, triplicate microcosms were sacrificed by sampling the headspace for volatile FTOHs followed by sequential extraction of soil for the parent monomers as well as transient and terminal degradation products. Both FTAC and FTMAC were hydrolyzed at the @entity13507 linkage as evidenced by 8:2 FTOH production. 8:2 FTAC and FTMAC degraded rapidly with half-lives    5d and 15d, respectively. Maximum 8:2 FTOH levels were 6-13mol% within 3-6d. Consistent with the known biotransformation pathway of 8:2 FTOH, FT @entity7574 and perfluoroalkyl carboxylic acids were subsequently generated including up to 10.3mol% of @entity2207 (105d). A total mass balance (parent plus metabolites) of 50-75mol% was observed on the last sampling day. 7:2 sFTOH, a direct precursor to @entity2207 , unexpectedly increased throughout the incubation period. The likely, but unconfirmed, concomitant production of acrylic acids was proposed as altering expected degradation patterns. Biotransformation of 8:2 FTAC, 8:2 FTMAC, and previously reported 8:2 FT-stearate for the same soils revealed the effect of the non-fluorinated terminus group linked to the FT chain on the electronic differences that affect microbially-mediated ester cleavage rates.

Microbial transformation of 8:2 fluorotelomer acrylate and XXXX in aerobic soils.

@entity2206 :: ('MESH:C023036', 'Chemical') :: ['perfluorooctanoic acid'] @entity7574 :: ('MESH:D002264', 'Chemical') :: ['carboxylic acids'] @entity11379 :: ('CHEBI:25218', 'Chemical') :: ['methacrylate'] @entity2207 :: ('CHEBI:35549', 'Chemical') :: ['PFOA'] @entity13507 :: ('CHEBI:35701', 'Chemical') :: ['ester']
@entity11379 :: (CHEBI:25218,Chemical) :: ['methacrylate']
