Aims. To identify prevalence, severity, and environmental determinants of @entity353 in @entity29 ( @entity29 ) @entity1 just prior to time of formal diagnosis. Methodology. @entity29 @entity1 attending outpatient clinic were questioned about @entity353 prior to diagnosis and other environmental and demographic variables. The percentage BMI loss was calculated for each subject and factors associated with @entity353 were determined. Results. Four hundred and ninety-four subjects were recruited (237 cases of @entity30 ( @entity30 ) and 257 cases of @entity31 ( @entity31 )). Overall, 57% of subjects with @entity30 and 51% of subjects with @entity31 experienced significant @entity353 prior to diagnosis (>5% BMI loss). Younger age at diagnosis and history of previous @entity29 surgery were significantly associated with both lower BMI at diagnosis and increased @entity353 prior to diagnosis. In @entity30 @entity1 , increasing age at diagnosis was inversely associated with @entity353 prior to diagnosis. @entity4628 was a risk factor of @entity353 , whereas prior appendectomy was associated with reduced risk of @entity353 . Conclusions. Weight loss is a significant problem for many @entity29 @entity1 at presentation, especially in younger age and @entity30 with ileal involvement. Appendectomy is associated with diminished @entity353 .

Determinants of Weight Loss prior to Diagnosis in XXXX : A Retrospective Observational Study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity4628 :: ('MESH:D007077', 'Disease') :: ['Ileal disease'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease', 'IBD'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"]
@entity29 :: (MESH:D015212,Disease) :: ['Inflammatory Bowel Disease']
