We studied the effect of preoperative determinants on early outcomes of 1028 consecutive @entity1 heart operations in a limited-resource setting. Comprehensive data on pediatric heart surgery (January 2010-December 2012) were collected prospectively. Outcome measures included in-hospital mortality, prolonged ventilation (>48 hours), and @entity281 ( @entity281 ) after surgery. Preoperative variables that showed significant individual association with outcome measures were entered into a logistic regression model. Weight at birth was low in 224 @entity1 (21.8%), and @entity177 to thrive was common (mean-weight Z score at surgery was 2.72    1.7). Preoperatively, 525 @entity1 (51%) needed intensive care, 69 @entity1 (6.7%) were ventilated, and 80 @entity1 (7.8%) had @entity281 . In-hospital mortality (4.1%) was significantly associated with risk adjustment for congenital heart surgery-1 (RACHS-1) risk category (P < 0.001). Neonatal status, preoperative @entity281 , and requirement of preoperative intensive care and ventilation had significant individual association with adverse outcomes, whereas low birth weight, @entity3465 , and severe @entity177 to thrive (weight Z score <-3) were not associated with adverse outcomes. On multivariable logistic regression analysis, @entity295 (odds ratio = 2.86; 95% CI: 1.32-6.21; P = 0.008) was associated with mortality. Preoperative intensive care unit stay, ventilation, @entity281 , and RACHS-1 category were associated with @entity86 . Neonatal age group was additionally associated with @entity86 . Although severe @entity177 to thrive was common, it did not adversely affect outcomes. In conclusions, preoperative @entity281 , preoperative intensive care, and mechanical ventilation are strongly associated with adverse outcomes after @entity1 cardiac surgery in this large single-center experience from a developing country. @entity11360 and low birth weight do not appear to adversely affect surgical outcomes.

Preoperative Determinants of Outcomes of XXXX Heart Surgery in a Limited-Resource Setting.

@entity1 :: ('9606', 'Species') :: ['infants', 'infant'] @entity295 :: ('MESH:D018805', 'Disease') :: ['preoperative sepsis'] @entity3465 :: ('MESH:C536271', 'Disease') :: ['prematurity'] @entity11360 :: ('MESH:D005183', 'Disease') :: ['Failure to thrive'] @entity177 :: ('MESH:D051437', 'Disease') :: ['failure'] @entity281 :: ('MESH:D007239', 'Disease') :: ['bloodstream infection', 'BSI'] @entity86 :: ('MESH:D019106', 'Disease') :: ['prolonged postoperative ventilation and postoperative sepsis', 'postoperative sepsis']
@entity1 :: (9606,Species) :: ['Infant']
