BACKGROUND: Acute disseminated @entity1651 (ADEM) is a monophasic @entity17 of the central nervous system, typically occurring after @entity281 or vaccinations. To our knowledge, scrub typhus has not been described in association with ADEM. CASE REPORT: A 77-year-old @entity1 was admitted with fever, @entity410 and an altered level of consciousness. On neurological examination, the @entity1 was stuporous and had @entity2003 and @entity1269 . A generalized @entity410 was observed. Serum and cerebrospinal fluid samples were positive for anti-Orientia tsutsugamushi antibody. Despite a 10-day course of parenteral @entity1214 , his clinical condition deteriorated. Serial cranial magnetic resonance images demonstrated progressively extensive areas of signal hyperintensity on conventional T2-weighted and fluid attenuated inversion recovery sequence images, mainly affecting the periventricular white matter. After administration of intravenous high-dose corticosteroids, the @entity1 had limited improvement. CONCLUSIONS: This is the first identifiable case of ADEM temporally associated with @entity9556 .

Scrub typhus-associated acute disseminated XXXX .

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity17 :: ('MESH:D003711', 'Disease') :: ['demyelinating disease'] @entity410 :: ('MESH:D012640', 'Disease') :: ['convulsions', 'tonic-clonic seizure'] @entity2003 :: ('MESH:D009127', 'Disease') :: ['nuchal rigidity'] @entity1214 :: ('MESH:D008911', 'Chemical') :: ['minocycline'] @entity9556 :: ('MESH:D012612', 'Disease') :: ['scrub typhus alone'] @entity1269 :: ('MESH:D010291', 'Disease') :: ['left hemiparesis'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity1651 :: ('MESH:D004679', 'Disease') :: ['encephalomyelitis']
@entity1651 :: (MESH:D004679,Disease) :: ['encephalomyelitis']
