OBJECTIVE: To determine the cumulative incidence and clinical predictors of @entity410 and @entity302 after pediatric arterial @entity385 (AIS). METHODS: We performed a retrospective analysis of 218 @entity1 with neonatal AIS (NAIS), presumed perinatal AIS (PPAIS), and childhood AIS (CAIS) from a single-center prospective consecutive cohort enrolled from 2006 to 2014. Medical records were reviewed for timing, semiology, and treatment of acute symptomatic @entity410 , @entity410 ( @entity410 ), and @entity302 . Cumulative incidence of @entity410 and @entity302 were assessed using survival analysis. RESULTS: Acute symptomatic @entity410 occurred in 94% of NAIS (n = 70/74) and 17% of CAIS (n = 18/105). Younger @entity1 were more likely to present with @entity410 at @entity64 ictus, and acute symptomatic @entity410 were predictive of later @entity410 and @entity302 in CAIS. Median follow-up for the entire cohort was 34 months, interquartile range 44.9 months (16.3-61.2). Estimated cumulative incidence of @entity410 at 2 years was 19% in NAIS, 24% in PPAIS, and 7% in CAIS. Estimated cumulative incidence of @entity302 at 2 years was 11% in NAIS, 19% in PPAIS, and 7% in CAIS. The median time to these outcomes was <2 years in all @entity64 subtypes. Among @entity1 developing @entity302 (n = 34), @entity410 were often well-controlled at last follow-up with median Engel class of <= 2 (<1 @entity410 /month). CONCLUSIONS: @entity410 and @entity302 are important neurologic sequelae of pediatric AIS. @entity1 with perinatal @entity64 and CAIS with acute symptomatic @entity410 are at increased risk of these outcomes. These cohorts need further study to identify biomarkers and potential therapeutic targets for epileptogenesis.

Incidence and predictors of @entity302 after pediatric arterial XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'children', 'Children'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures', 'remote symptomatic seizures', 'RSS'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['ischemic stroke']
