OBJECTIVE: To investigate differences in MRI features between two etiologically distinct subtypes of @entity626 ( @entity571 ): one group with @entity209 and one lean group with frequent physical activity. METHODS: We included two groups of 50 subjects of the @entity571 ( @entity571 ) incidence subcohort, with KL  >=   2 in at least one knee at 48 months follow-up. Inclusion criteria for the @entity209 group were a body mass index (BMI)  >=   30  kg/m(2) and two out of three of the following criteria: @entity101 (RR  >  130/85  mm  Hg or @entity101 medication), @entity2690 resistance (high blood sugar or @entity6 medication) or @entity2299 (lipid lowering medication). Inclusion criteria for the active lean group were a BMI  <  25  kg/m(2) and a Physical Activity Scale for the Elderly (PASE) score  >=   2. MRI scans were scored using MR Imaging @entity571 Knee Score (MOAKS). Differences in MOAKS items between groups were tested using generalized linear models adjusted for sex and age. RESULTS: Scores for cartilage damage were significantly higher in the patella, trochlea and lateral femur in the @entity209 group. Osteophyte scores were higher for all compartments in the @entity209 group, though only significant for the patella, trochlea and medial tibia. @entity603 was significantly more prevalent in the active lean group while prepatellar bursa signal was more prevalent in the @entity209 group. CONCLUSION: @entity209 and @entity571 related to physical activity showed differences in MRI features, depending on knee compartment. These results show that different etiological processes in knee @entity571 can lead to differences in structural degradation.

Differences in MRI features between two different @entity571 subpopulations: data from the XXXX .

@entity626 :: ('MESH:D020370', 'Disease') :: ['knee osteoarthritis'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity571 :: ('MESH:D010003', 'Disease') :: ['Osteoarthritis Initiative', 'OA', 'Osteoarthritis', 'OAI'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity2690 :: ('3630', 'Gene') :: ['insulin'] @entity603 :: ('MESH:D013585', 'Disease') :: ['Hoffa synovitis'] @entity209 :: ('MESH:D008659', 'Disease') :: ['Metabolic OA', 'metabolic syndrome']
@entity571 :: (MESH:D010003,Disease) :: ['Osteoarthritis Initiative']
