Observational and experimentally induced @entity281 studies show that @entity1729 ( @entity1729 ) affect mood and cognition. This study tested the effects of naturally occurring @entity1729 on cognition, mood and emotional processing, using a prospective design, with a broader array of tests than previous research, and with well matched control @entity1 . Eighty @entity1 (42 younger, M age 20.3 years; 38 older, M age 64.3 years) underwent neuropsychological assessment at baseline. Once a @entity1 had @entity1729 symptoms, s/he and a healthy, matched @entity1 were retested. The Cognitive Drug Research computerised assessment battery was used to assess Power and Continuity of Attention, Quality of Episodic and Working Memory, Speed of Memory, and mood. Additionally, emotional processing was measured on matching of emotionally-negative faces with faces and faces with labels. Forty-two of 80 @entity1 were matched (21 well, 21 ill). Well @entity1 improved in Speed of Memory and face-label reaction time. Despite a lack of fever, ill @entity1 demonstrated significantly smaller improvements. Older @entity1 reported feeling less alert if ill, and less stressed if well, than at baseline. All ill @entity1 reported less contentment than at baseline than well @entity1 . Severity of @entity1729 symptoms correlated with changes in Speed of Memory and mood. Even without fever, @entity166 produces large disturbances in speed of cognitive processing, particularly that reflecting retrieval from memory, and these effects are more marked in older @entity1 . URTIs also affect mood. Future studies need to examine the role of inflammatory molecules and the brain regions implicated in mediating these findings.

Selective effects of upper respiratory tract XXXX on cognition, mood and emotion processing: a prospective study.

@entity1 :: ('9606', 'Species') :: ['participants', 'participant'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious disease'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['upper respiratory tract infections', 'URTI']
@entity281 :: (MESH:D007239,Disease) :: ['infection']
