BACKGROUND: @entity2101 ( @entity2101 ) has improved the accuracy of manometry in detecting @entity1318 and has helped distinguish between clinically relevant subtypes. This study investigated whether @entity2101 metrics correlate with the @entity1318 symptoms and symptomatic outcomes of peroral esophageal myotomy (POEM). METHODS: Of the 30 @entity1 who were enrolled, 25 were treated with POEM, 12 of who underwent @entity2101 after 3 months. All the @entity1 completed the Eckardt score questionnaires, and those who underwent POEM were followed up for about 6 months. Pearson correlation was used to assess the relationship between the @entity2101 metrics and symptoms and outcomes. KEY RESULTS: The integrated relaxation pressure (IRP) score positively correlated with the total Eckardt score, regurgitation score and weight loss score in all the @entity1 , and with the weight loss score in type I @entity1318 . In 25 @entity1 (10 @entity1 , type I; 15 @entity1 , type II) who underwent POEM, the total Eckardt scores and individual symptom scores significantly decreased after surgery. Changes in the Eckardt scores were similar between type I and type II. Further, the Eckardt scores and weight loss score changes were positively correlated with baseline IRP. Twelve @entity1 (4 @entity1 , type I; 8 @entity1 , type II) underwent @entity2101 again after POEM. IRP changed significantly after POEM, as did the DEP in type II. The IRP changes after POEM were positively correlated with the Eckardt score changes. CONCLUSIONS _ INFERENCES: IRP is correlated with the symptoms and outcomes of @entity1318 @entity1 . Thus, @entity2101 is effective for assessing the severity of @entity1318 and can predict the efficacy of POEM.

Association of High-Resolution Manometry Metrics with the Symptoms of XXXX and the Symptomatic Outcomes of Peroral Esophageal Myotomy.

@entity1318 :: ('MESH:D004931', 'Disease') :: ['achalasia'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity2101 :: ('MESH:C538394', 'Disease') :: ['HRM', 'High-resolution manometry']
@entity1318 :: (MESH:D004931,Disease) :: ['Achalasia']
