OBJECTIVE: The aim of this study was to use the Swedish National Registry of @entity150 (SNRUBC) to investigate changes in @entity1 and @entity5 characteristics, management and survival in @entity150 cases over a period of 15 years. MATERIALS AND METHODS: All @entity1 with newly detected @entity150 reported to the SNRUBC during 1997-2011 were included in the study. The cohort was divided into three groups, each representing 5 years of the 15 year study period. RESULTS: The study included 31,266 @entity1 (74% @entity1 , 26% @entity1 ) with a mean age of 72 years. Mean age was 71.7 years in the first subperiod (1997-2001) and 72.5 years in the last subperiod (2007-2011). Clinical T categorization changed from the first to the last subperiod: Ta from 45% to 48%, T1 from 21.6% to 22.4%, and T2-T4 from 27% to 25%. Also from the first to the last subperiod, intravesical treatment after transurethral resection for T1G2 and T1G3 @entity5 increased from 15% to 40% and from 30% to 50%, respectively, and cystectomy for @entity5 increased from 30% to 40%. No differences between the analysed subperiods were found regarding relative survival in @entity1 with T1 or @entity5 , or in the whole cohort. CONCLUSIONS: This investigation based on a national @entity150 registry showed that the age of the @entity1 at diagnosis increased, and the proportion of muscle-invasive @entity5 decreased. The treatment of all @entity5 stages became more @entity146 but relative survival showed no statistically significant change over time.

Swedish National Registry of @entity150 : No difference in relative survival over time despite more XXXX treatment.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients', 'patient'] @entity150 :: ('MESH:D001749', 'Disease') :: ['Urinary Bladder Cancer', 'bladder cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['T2-T4 tumours', 'tumours', 'tumour'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive']
@entity146 :: (MESH:D001523,Disease) :: ['aggressive']
