BACKGROUND: Matrix metalloproteinases (MMPs) and Tissue Inhibitor of Matrix Metalloproteinases (TIMPs) may be associated with atherogenesis and @entity397 . We evaluated the relationship between @entity3334 , @entity1495 , @entity2843 and @entity650 levels and risk factors, presentation, extent and severity of @entity453 ( @entity453 ). METHODS: Consecutive @entity1 who underwent coronary angiography were randomly included. The serum concentrations of @entity3334 , @entity1495 , @entity2843 and @entity650 were analyzed with ELISA method in 134 @entity1 . @entity1 were divided into 5 groups; @entity5749 ( @entity5749 ; n= 34), unstable @entity951 (USAP; n=29), @entity583 ( @entity583 ; n=16), @entity583 ( @entity583 ; n=25) and controls (n=30). Coronary angiographic Gensini score was calculated. RESULTS: @entity3334 levels were higher in @entity583 and @entity583 groups compared with USAP, @entity5749 and control groups ( @entity583 vs USAP p=0.005; @entity583 vs @entity5749 p=0.001; @entity583 vs control p<0.001; @entity583 vs USAP p=0.02; @entity583 vs @entity5749 p=0.027; @entity583 vs control p<0.001). In @entity583 group, @entity1495 levels were higher than USAP and control groups (p=0.002; p<0,001). @entity2843 levels were not significantly different within all 5 groups. @entity3334 levels were found to be elevated in @entity6 @entity1 (p=0.020); whereas @entity1495 levels were higher in smokers (p=0.043). Higher @entity3334 , @entity1495 and @entity650 levels were correlated with severe @entity6128 ( @entity6128 ) @entity850 and higher angiographic Gensini Score (for severe @entity6128 @entity850 ; r = 0.671, 0.363, 0.509 p<0.001; for Gensini score; r = 0.717, 0.371, 0.578 p<0.001). CONCLUSIONS: Serum levels of @entity3334 , @entity1495 , and @entity650 are elevated in @entity1 with @entity453 ; more so in @entity1187 . @entity3334 , @entity1495 and @entity650 are associated with more extensive and severe @entity453 (as represented by Gensini score).

Relationship Between @entity3334 , @entity1495 , @entity2843 , @entity650 and Risk Factors, Clinical Presentation, Extent and Severity of XXXX .

@entity1 :: ('9606', 'Species') :: ['Participants', 'patients'] @entity650 :: ('3569', 'Gene') :: ['IL-6'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndromes'] @entity3334 :: ('4312', 'Gene') :: ['MMP-1'] @entity583 :: ('MESH:D009203', 'Disease') :: ['NSTEMI', 'STEMI', 'acute ST elevation myocardial infarction', 'non-ST elevation myocardial infarction'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity5749 :: ('MESH:D060050', 'Disease') :: ['SAP', 'stable angina pectoris'] @entity6128 :: ('MESH:D020243', 'Disease') :: ['LAD', 'Left Anterior Descending artery'] @entity2843 :: ('7076', 'Gene') :: ['TIMP-1'] @entity397 :: ('MESH:D012421', 'Disease') :: ['plaque rupture'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina pectoris'] @entity1495 :: ('4318', 'Gene') :: ['MMP-9'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'atherosclerotic coronary artery disease'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis']
@entity453 :: (MESH:D003324,Disease) :: ['Atherosclerotic Coronary Artery Disease']
