Sentinel lymph node biopsy is an established way of predicting axillary nodal @entity3 in early @entity0 . Intraoperative @entity2585 ( @entity2585 ) of sentinel lymph nodes (SLNs) can be used to detect metastatic disease, allowing immediate axillary lymph node dissection. The purpose of this study was to evaluate the accuracy of intraoperative @entity2585 in evaluation of sentinel lymph nodes in cases of @entity0 . Between March 2006 and August 2010, a total of 164 @entity1 with clinically node-negative operable @entity0 were subjected to sentinel lymph node biopsy of axillary lymph nodes using preoperative peritumoral injection of radioactive colloid and @entity6693 . Intraoperative identification of sentinel nodes was done using a handheld gamma probe and identification of blue-stained nodes. The nodes were sent for frozen section examination. The results of frozen section were compared with the final histopathology. Out of the 164 cases, @entity3 were detected in @entity4298 by frozen section in 38 cases. There were three false-negative cases (all showing micrometastasis on final histopathology). @entity2585 had sensitivity of 92.6  %, specificity of 100  %, and overall accuracy of 98.1  %. The positive predictive value was 100  %, and the negative predictive value was 97.6  %. @entity2585 for diagnosis of @entity3 of SLNs is reliable. @entity1 with negative SLNs by the @entity2585 diagnosis can avoid reoperation for axillary lymph node dissection. However, @entity2585 may fail to detect micrometastases, especially in cases with small @entity5 .

Intraoperative Frozen Section Evaluation of Sentinel Lymph Nodes in XXXX : Single-Institution Indian Experience.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity6693 :: ('MESH:D008751', 'Chemical') :: ['methylene blue'] @entity4298 :: ('6588', 'Gene') :: ['SLN'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity2585 :: ('MESH:D002062', 'Disease') :: ['FS', 'frozen sections']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Carcinoma']
