OBJECTIVE: The aim of this prospective study was to detect minimal clinically important improvement (MCII) of oral health impact profile-14 (OHIP-14) for assessing the effect of treatments for @entity9645 in @entity195 ( @entity195 ). METHODS: @entity195 @entity1 with active @entity9645 (F/M:36/22) were selected. Baseline and follow-up data were collected by clinical examinations and questionnaires. @entity1 rated their global impression of change (PGIC) measured by a transitional question. MCII was defined as the difference in mean change from baseline in OHIP-14 between @entity1 with no response to therapy and @entity1 with next higher level of response. RESULTS: Approximately one third (29.3 %) of the @entity1 expressed an improvement during control examinations. A significant correlation was observed between raw change in OHIP-14 score and change in number of @entity9645 (r=0.69 p=0.017). Inactive @entity1 increased from 44.1% in baseline to 58.8% in follow-up examination. A trend towards decreased number of @entity9645 was observed in follow-up (0.64+/-0.93) compared to baseline (1.44+/-1.92) in the improved group (p=0.096). According to regression analysis, PGIC was a significant predictor of change in raw OHIP-14 score. The threshold levels generated from the ROC analyses in OHIP-14 score best associated with clinically important improvement were -3.5 points (sensitivity: 80%, specificity: 88.6%) and -38.1% (sensitivity: 86.7%, specificity: 97.1%) respectively. CONCLUSION: Changes in OHIP-14 scores seem to be a sensitive and valuable tool for the determination of MCII during follow-up of @entity195 @entity1 for oral disease assessment.

Assessment of minimal clinically important improvement by using Oral Health Impact Profile-14 in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity9645 :: ('MESH:D019226', 'Disease') :: ['oral ulcers'] @entity195 :: ('MESH:D000544', 'Disease') :: ["Beh  et's disease", 'BD']
@entity195 :: (MESH:D000544,Disease) :: ['Beh  et's disease']
