AIMS: The aims of this study were as follows: (i) To assess the prevalence of @entity2521 among @entity1 with primary @entity244 (pSS) and comparator groups of @entity1 with @entity309 ( @entity309 ) and @entity571 ( @entity571 ). (ii) To perform a pilot study to compare serum antibody responses to 10 oral/periodontal bacteria in these @entity1 groups and a historical comparator group of @entity1 with @entity2521 . MATERIALS AND METHODS: Standard clinical periodontal assessments were performed on 39 pSS, 36 @entity309 and 23 @entity571 @entity1 and "In-house" antibody ELISAs for serum antibodies against 10 oral/periodontal bacteria were performed in these groups. RESULTS: Forty-six percent of the pSS group, 64% of the @entity309 group and 48% of the @entity571 group had moderate/severe @entity2521 . These frequencies did not reach statistical significance between groups. Raised antibody levels to @entity14262 were found in the pSS, @entity309 and @entity2521 groups compared to the @entity571 group. Significant between group differences were seen for @entity3841 , @entity3288 and Campylobacter showae. None of these differences were specifically associated with pSS. CONCLUSION: This study showed no increase in @entity2521 in pSS @entity1 . Although the @entity14262 data are of interest, identifying bacterial triggering factors for pSS will likely require alternative strategies including modern techniques such as microbiome analysis.

@entity2521 prevalence and serum antibody reactivity to periodontal bacteria in primary XXXX : a pilot study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity571 :: ('MESH:D010003', 'Disease') :: ['OA', 'osteoarthritis'] @entity3288 :: ('28131', 'Species') :: ['Prevotella intermedia'] @entity244 :: ('MESH:D014899', 'Disease') :: ["Sj  gren's syndrome"] @entity2521 :: ('MESH:D010518', 'Disease') :: ['periodontitis'] @entity3841 :: ('714', 'Species') :: ['Aggregatibacter actinomycetemcomitans'] @entity14262 :: ('28129', 'Species') :: ['P.  denticola', 'Prevotella denticola'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA']
@entity244 :: (MESH:D014899,Disease) :: ['Sj  gren's syndrome']
