The @entity1 was a 73-year-old @entity1 . At 63 years of age, she had developed @entity706 that showed a complete response to R- @entity3726 therapy. Over the subsequent 8 years, she experienced 4 relapses and was administered rituximab monotherapy once, combined rituximab- @entity3118 therapy twice, and CHASE-R therapy once, achieving a complete response each time. Before her first therapy, @entity1956 virus (HBV) surface antigen was negative, while @entity1956 surface antibody (anti-HBs) and @entity1956 core antibody were not measured. Later, before her second salvage therapy, anti-HBs was negative, but then changed to positive before her third salvage therapy. @entity97 -DNA was negative before CHASE-R therapy. At 16 months after completing the CHASE-R therapy, she developed @entity99 and @entity97 -DNA had changed to positive. @entity99 did not become fulminant and @entity17705 administration was effective. It was surmised that @entity97 had resolved, but she became negative for anti-HBs following the rituximab-containing chemotherapy. Therefore, this is a rare case in which de novo @entity99 developed after the final chemotherapy. The prognosis of @entity1 with de novo @entity99 accompanying treatment of @entity1892 is poor. In those who undergo @entity706 salvage therapy, the risk for and clinical course of @entity97 reactivation might differ from those of treatment-na  ve @entity1 .

@entity1892 developing de novo XXXX after salvage therapies including rituximab through seroconversion of surface antibody.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'patient'] @entity97 :: ('10407', 'Species') :: ['HBV'] @entity1956 :: ('MESH:D006509', 'Disease') :: ['hepatitis B'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma', 'follicular lymphoma'] @entity3726 :: ('1649', 'Gene') :: ['CHOP'] @entity17705 :: ('MESH:C413685', 'Chemical') :: ['entecavir'] @entity3118 :: ('MESH:C024352', 'Chemical') :: ['fludarabine'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['B-cell lymphoma'] @entity99 :: ('MESH:D056486', 'Disease') :: ['Hepatitis', 'hepatitis']
@entity1956 :: (MESH:D006509,Disease) :: ['hepatitis B']
