BACKGROUND: Outbreaks of @entity281 occur in several parts of India with clockwork precision closely related to changing seasons. Most recent outbreak in Puducherry occurred between October 2012 and January 2013, affected a sizable pediatric population. A prospective study was done to characterize the demographic, diagnostic and clinical profile of pediatric @entity1 in a tertiary care center in Puducherry. MATERIALS AND METHODS: Data of @entity1 serologically positive for either dengue @entity8768 antigen or anti-dengue IgM antibodies were analyzed. Duration of @entity221 , platelet count, complications, risk factors, morbidity and mortality were analyzed. RESULTS: Among pediatric cases with @entity221 who were screened for @entity8768 /IgM antibody during the recent outbreak, 161 (37.5%) tested positive. @entity8768 was detected in 85% while 5.5% tested positive for IgM and 3% for IgG. Few (4.9%) tested positive for both @entity8768 and IgM and 1.2% were positive for both @entity8768 and IgG. The mean age was 6 years of which 9% were <1-year, the youngest being 1-month old @entity1 . Mean duration of @entity221 was 4 days. Vomiting was associated in 42% of cases. @entity882 (51%) and @entity382 (41%) were two major observations. Among the @entity8768 positive cases, 49% had @entity882 . IgM alone and @entity8768 with IgM were associated with @entity882 in 67% and 78% respectively. 14 @entity1 had complications of @entity7643 , and four had @entity7643 . Totally, 22 of the @entity1 had platelet transfusion. There was no mortality reported among any of these @entity1 . CONCLUSION: Combination of clinical findings and rapid @entity8768 , IgM detection helped in confirming the diagnosis for appropriate management of dengue in @entity1 .

Dengue virus infection: Need for appropriate laboratory tests for diagnosis and management of the condition in XXXX during an outbreak.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'infant'] @entity882 :: ('MESH:D013921', 'Disease') :: ['Thrombocytopenia', 'thrombocytopenia'] @entity7643 :: ('MESH:D019595', 'Disease') :: ['dengue hemorrhagic fever', 'dengue shock syndrome'] @entity281 :: ('MESH:D007239', 'Disease') :: ['dengue infection'] @entity382 :: ('MESH:D006529', 'Disease') :: ['hepatomegaly'] @entity8768 :: ('10625', 'Gene') :: ['NS1'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever']
@entity1 :: (9606,Species) :: ['children']
