BACKGROUND: The right ventricle is multicompartmental in orientation. OBJECTIVE: To assess the normal differential function of the right ventricular (RV) inflow, apical and outflow compartments, also their inter-relations and the response to @entity120 ( @entity120 ). METHODS: 45 @entity1 were studied--16 controls and 29 @entity1 with @entity712 , 15 without (group 1) and 14 with (group 2) secondary @entity120 , using two-dimensional (2D) and 3D echocardiography in addition to conventional Doppler techniques. RESULTS: There was a strong correlation between RV inlet diameter (2D) and end-diastolic volume (3D) (r=0.69, p<0.001) and between tricuspid annular plane systolic excursion and RV ejection fraction (3D) (r=0.71, p<0.001). In controls and @entity1 , the apical ejection fraction was less than the inflow and outflow (controls: p<0.01 and p<0.01, group 1: p<0.05 and p<0.01 and group 2: p<0.05 and p<0.01, respectively). Ejection fraction was reduced in @entity1 (inflow: p<0.001 for both, apical: p<0.01 for both and outflow tract: p<0.05 for both). In controls, the inflow compartment reached the minimum volume 20_emsp14;ms before the outflow and apex but in group 2 it was simultaneous. Isovolumic contraction and relaxation times were prolonged in @entity1 (Group 1: p=0.02 and p<0.01 and Group 2: p=0.01 for both). Peak RV ejection time correlated with the rate of outflow volume fall in controls but with the apex in group 2 (r=0.6, p<0.05). CONCLUSION: The right ventricle has distinct features for the inflow, apical and outflow tract compartments, with different extent of contribution to the overall systolic function. In @entity120 , the right ventricle becomes one dyssynchronous compartment, which itself may have perpetual effect on overall @entity299 .

Differential right ventricular regional function and the effect of XXXX : three-dimensional echo study.

@entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity712 :: ('MESH:D006333', 'Disease') :: ['left-sided heart failure'] @entity120 :: ('MESH:D006976', 'Disease') :: ['PAH', 'pulmonary arterial hypertension'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac dysfunction']
@entity120 :: (MESH:D006976,Disease) :: ['pulmonary hypertension']
