BACKGROUND: @entity12045 are infections with a high mortality rate. In last years the incidence of these infections has increased probably because of the growing population of immunocompromised @entity1 who undergo aggressive diagnostic and therapeutic techniques. OBJECTIVE: To know the epidemiologic characteristics, risk factors, clinical features and prognosis of @entity12045 . @entity1 AND METHODS: We prospectively evaluated all the @entity1 with proven @entity12045 in our center during a 5 year-period. After finishing antifungal treatment a minimum follow-up of 1 month was carried out. Fungal isolation and identification were performed by standard tests. RESULTS: During the period of study we evaluated 81 @entity1 with an episode of @entity12045 . Global incidence was 0,9 episodes per thousand admitted @entity1 . @entity5132 was the more frequently isolated species (n=53), followed by @entity7409 (n=11), @entity9841 (n=6) and @entity7408 (n=5). Most of the @entity1 had a central intravenous line and were on parenteral nutrition therapy. All of them previously received at least one course of broad-spectrum antibiotics. Overall mortality was 49,6%. A worst prognosis was significantly associated with: age over 65 years, surgical procedures during present admission, leucocytosis, shock, and delay in antifungal treatment. CONCLUSIONS: Fungal bloodstream infection incidence is high in our environment. It is associated with a high mortality rate, specially in @entity1 in whom the beginning of antifungal treatment was delayed. A higher clinical suspicion index may improve the poor outcome in these @entity1 .

[ XXXX in a general hospital. Epidemiology and prognostic factors. Prospective study 1993-1998].

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity9841 :: ('5482', 'Species') :: ['C. tropicalis'] @entity7408 :: ('5478', 'Species') :: ['C. glabrata'] @entity7409 :: ('5480', 'Species') :: ['C. parapsilosis'] @entity5132 :: ('5476', 'Species') :: ['Candida albicans'] @entity12045 :: ('MESH:D016469', 'Disease') :: ['nosocomial fungemia', 'fungemia', 'Nosocomial fungemias']
@entity12045 :: (MESH:D016469,Disease) :: ['Nosocomial fungemias']
