CONTEXT: Identification of @entity5 @entity1 with similar symptom profiles may facilitate targeted symptom management. OBJECTIVES: To identify subgroups of @entity0 survivors based on differential experience of symptoms, examine change in subgroup membership over time, and identify relevant characteristics and quality of life (QOL) among subgroups. METHODS: Secondary analyses of data from 653 @entity0 survivors recruited within eight months of diagnosis who completed questionnaires at five time points. @entity3628 was used to 1) formulate symptom profiles based on prevalence and severity of eight symptoms commonly associated with @entity0 and 2) estimate probabilities of changing subgroup membership over 18  months of follow-up. Ordinal repeated measures were used to 3) identify @entity1 characteristics related to subgroup membership and 4) evaluate the relationship between symptom subgroup and QOL. RESULTS: A seven-subgroup model provided the best fit: 1) low symptom burden, 2) mild @entity1295 , 3) mild @entity1295 and mild @entity158 , 4) moderate @entity1295 and moderate @entity158 , 5) moderate @entity1295 and moderate psychological, 6) moderate @entity1295 , mild @entity158 , mild psychological, and 7) high symptom burden. Seventy percent of survivors remained in the same subgroup over time. In multivariable analyses, chemotherapy and greater illness intrusiveness were significantly related to greater symptom burden, while not being married or partnered, no difficulty paying for basics, and greater social support were protective. Higher symptom burden was associated with lower QOL. Survivors who reported @entity1109 had significantly lower QOL than did survivors with @entity158 symptoms. CONCLUSION: @entity5 survivors can be differentiated by their symptom profiles.

Longitudinal Examination of Symptom Profiles Among XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'Cancer'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['psychological symptoms'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity3628 :: ('MESH:D004195', 'Disease') :: ['Hidden Markov modeling'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Cancer Survivors']
