PURPOSE: To evaluate clinical safety and effectiveness of a novel @entity460 -incorporated @entity702 implant surface (Xpeed, MegaGen Implant Co., Gyeongbuk, South Korea). MATERIALS AND METHODS: Sixty @entity1 were randomised to receive one to six implants in the maxilla with either @entity460 -incorporated (Xpeed) or control resorbable blasted media (RBM) surfaces, according to a parallel group design at two centres. Implants were submerged and exposed at three different endpoints in equal groups of 20 @entity1 , each at 12, 10 and 8 weeks, respectively. Within 2 weeks, implants were functionally loaded with provisional or definitive prostheses. Outcome measures were prosthesis failures, implant failures, any complications and peri-implant marginal bone level changes. RESULTS: Thirty @entity1 received 45 @entity460 -incorporated implants and 30 @entity1 received 42 control @entity702 implants. Three years after loading four @entity1 dropped-out from the Xpeed group and one from the RBM group. No prosthesis or implant failures occurred. There were no statistically significant differences between the groups for complications (P = 0.91; difference in proportions = 0.79 %; 95% CI -0.71 to 2.29) and mean marginal bone level changes (P = 0.88; mean difference = -0.02 mm; 95% CI -0.26 to 0.22). CONCLUSIONS: Both implant surfaces provided good clinical results and no significant difference was found when comparing @entity702 implants with a nanostructured @entity460 -incorporated surface versus implants with RBM surfaces.

Safety and effectiveness of early loaded maxillary XXXX implants with a novel nanostructured @entity460 -incorporated surface (Xpeed): 3-year results from a pilot multicenter randomised controlled trial.

@entity702 :: ('MESH:D014025', 'Chemical') :: ['titanium'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium']
@entity702 :: (MESH:D014025,Chemical) :: ['titanium']
