BACKGROUND: The optimal method of diminutive polypectomy (<6mm) is unknown. OBJECTIVE: To assess the rates of incomplete resection of diminutive @entity1127 of the colon using three standard polyp resection techniques (hot @entity24332 , cold @entity24332 , and cold biopsy forceps). DESIGN: Randomized, pilot study. SETTINGS: Single-center endoscopy center. @entity1 : @entity1 undergoing routine outpatient colonoscopies. INTERVENTIONS: Polypectomy was performed using the method to which the @entity1 was randomized. Following retrieval of the polyp, the polypectomy base was lifted by submucosal injection of normal saline and then excised using the cold @entity24332 device. If no tissue could be removed, then at least four cold biopsies using forceps of the remaining margin were obtained. MAIN OUTCOME MEASURES: Adequacy of resection of diminutive @entity1127 , which was defined as no visible @entity652 or @entity5072 tissue seen in the base tissue on histology. RESULTS: A total of 60 @entity1 were enrolled (57% male), the mean age was 60 (range 33-82), and 62 @entity1127 were randomized from 37 @entity1 . The mean polyp size was 3.6mm (range 2-5mm) and 37 @entity1127 (60%) were adenomatous. Overall incomplete polyp resection rate was 9% (95%CI 3-19%), 5 of 37 (14%) for @entity652 . By the study arm, the incomplete resection rates were 1 of 18 (6%) for hot @entity24332 , 2 of 21 (10%) for cold @entity24332 , and 2 of 18 (11%) for cold biopsy forceps. The majority of polyp bases were removed with cold biopsy forceps since most of the endoscopists did not feel that the saline lift cold @entity24332 method was feasible or appropriate. LIMITATIONS: Small sample size; endoscopic mucosal resection (EMR) of the polyp base tissue was not routinely performed. CONCLUSIONS: Recruiting @entity1 to a pilot study that randomized @entity1127 to one of three common methods of polypectomy for diminutive @entity1127 was feasible, and approximately 1 in 10 diminutive @entity1127 found on colonoscopy were incompletely resected by standard polypectomy methods.

Diminutive colorectal polyp resection comparing hot and cold XXXX and cold biopsy forceps polypectomy. Results of a pilot randomized, single-center study (with videos).

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity24332 :: ('100170220', 'Gene') :: ['snare'] @entity5072 :: ('MESH:D000796', 'Disease') :: ['hyperplastic'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas', 'adenoma']
@entity24332 :: (100170220,Gene) :: ['snare']
