BACKGROUND/AIM: Magnetic resonance imaging (MRI) is a key modality not only for lesion diagnosis, but also to evaluate the extension, type and grade of the @entity5 . Advanced MRI techniques provide physiologic information that complements the anatomic information available from conventional MRI. The aim of this study was to determine whether there is a correlation between apparent diffusion coefficient (ADC) maps of intracranial @entity5 and histopathologic findings and whether ADCs can reliably distinguish low-grade from high-grade @entity11 . METHODS: This retrospective study included 25 @entity1 with MRI examination up to seven days before surgery, according to the standard protocol with the following sequences: T1WI, T2WI, FLAIR, DWI and post contrast T1WI. Data obtained from DW MRI were presented by measuring the value of ADC. The ADC map was determined by utilizing Diffusion-Perfusion (DP) Tools software. All the @entity1 underwent surgical resection of the @entity5 . Histological diagnosis of @entity5 was determined according to the World Health Organization (WHO) classification. The ADC values were compared with the histopathologic findings according to the WHO criteria. RESULTS: The ADC values of @entity816 grades I (0.000614 +/- 0.000032 mm2/s) were significantly higher (< 0.001) than the ADC values of @entity816 (0.000436 +/- 0.000016 mm2/s) and the ADC values of @entity463 multiforme (0.000070 +/- 0.000008 mm2/s). The ADC values of @entity816 grades II (0.000530 +/- 0.000114 mm2/s) were significantly higher (< 0.001) than the ADC values of @entity816 (0.000436 +/- 0.000016 mm2/s) and @entity463 multiforme (0.000070 +/- 0.000008 mm2/s). The ADC values of anaplastic astrocy-omas (0.000436 +/- 0.000016 mm2/s) were significantly higher (< 0.001) than the ADC values of @entity463 multiforme (0.000070 +/- 0.000008 mm2/s). The ADC values in the cystic part of the @entity5 for @entity816 grades I (0.000775 +/- 0.000023 mm2/s) were significantly higher (< 0.001) than the ADC values of @entity816 (0.000119 +/- 0.000246 mm2/s) and @entity463 multiforme (0.000076 +/- 0.000004 mm2/s). The ADC values @entity816 grades II (0.000511 +/- 0.000421 mm2/s) were significantly higher (< 0.001) than the ADC values of @entity463 multiforme (0.000076 +/- 0.000004 mm2/s). CONCLUSION: DWI with calculation of ADC maps can be regarded as a reliable useful diagnostic tool, which indirectly reflects the proliferation and @entity11 . The ADCs maps can both predict the results of histopathological @entity5 and distinguish between low- and high-grade @entity11 , and provide significant information for presurgical planning, treatment and prognosis for @entity1 with high-grade @entity816 .

Apparent diffusion coefficient in the evaluation of cerebral XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['glial tumors', 'tumor', 'tumors'] @entity11 :: ('MESH:D005910', 'Disease') :: ['malignancy of gliomas', 'gliomas'] @entity816 :: ('MESH:D001254', 'Disease') :: ['anaplastic astrocytomas', 'astrocytomas'] @entity463 :: ('MESH:D005909', 'Disease') :: ['glioblastomas']
@entity11 :: (MESH:D005910,Disease) :: ['gliomas malignancy']
