PURPOSE: When not recognized and treated aggressively, @entity3854 may progress and cause debilitating symptoms. It also may result in significant morbidity in @entity1 undergoing treatment for @entity3832 because unrecognized, it may result in rapid and severe recurrence after surgical treatment. We present our experience treating @entity1 with @entity3854 in an equal access health care system. MATERIALS AND METHODS: We performed an institutional review board approved retrospective review of all adult @entity1 with @entity3854 treated at our institution during a 10-year period. We analyzed all @entity1 diagnosed with @entity3854 , and recorded @entity1 demographics and therapies. We recorded characteristics of the disease process including external and internal manifestations. We also recorded the various treatments, and whether the @entity1 experienced recurrence. RESULTS: A total of 43 @entity1 were diagnosed with @entity3854 during the review period. Of those @entity1 presenting with more severe (urethral) involvement and undergoing 1 or 2-stage urethroplasties, we noted 7 with recurrence. In the remainder of @entity1 presenting with less severe disease who were treated aggressively with @entity6914 and/or minor procedures, no recurrences were noted on followup examination, and all of these @entity1 had documented normal flow patterns on noninvasive urodynamics. CONCLUSIONS: Our data suggest that early aggressive topical therapy plus minimally invasive surgical therapy to relieve high pressure voiding may prevent the progression of @entity3854 in @entity1 who present with limited disease involving the skin and meatus.

Early aggressive treatment of XXXX may prevent disease progression.

@entity3854 :: ('MESH:D018459', 'Disease') :: ['lichen sclerosus'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'men'] @entity6914 :: ('MESH:D002990', 'Chemical') :: ['clobetasol'] @entity3832 :: ('MESH:D014525', 'Disease') :: ['urethral strictures']
@entity3854 :: (MESH:D018459,Disease) :: ['lichen sclerosus']
