BACKGROUND: The association between @entity73 and @entity65 ( @entity65 ) risk factors has been shown in adults. However, there is little evidence of such an association in young adults, particularly from South America, where the burden of @entity65 and @entity1030 ( @entity1030 ) is as high as that observed in more developed countries. We therefore investigated the relation between @entity65 risk factors including @entity209 ( @entity209 ), and lung function status in young adults from Chile. METHODS: 970 subjects from a sample of 998 adults born between 1974 and 1978 in Limache, Chile were studied. A Spanish translation of the European Community Respiratory Health Survey (ECRHS) questionnaire was used. Forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) were measured. Weight, height, waist circumference (WC), blood pressure, Homeostatic model assessment (HOMA-IR), @entity1674 , high density lipoprotein (HDL), glycaemia, and @entity209 ( @entity209 ) were also assessed. RESULTS: The prevalence of @entity209 was 11.8%. A lower FEV1 and lower FVC were associated with having @entity209 (beta-coefficient -0.13; 95% Confidence Interval [CI] -0.21 to -0.05, and beta-coefficient -0.18; 95% CI -0.27 to -0.09, respectively). Both spirometric measures were also negatively associated with having an elevated HOMA-IR (beta-coefficient for FEV1 -0.08; 95% CI -0.13 to -0.03, and beta-coefficient for FVC -0.11; 95% CI -0.17 to -0.05). In males only, a lower FEV1 and FVC were associated with having elevated @entity1674 (beta-coefficient highest vs. lowest tertile -0.13, 95% CI -0.24 to -0.03, and beta-coefficient -0.13, 95% CI -0.25 to -0.01, respectively). In @entity1 , a higher FEV1 and FVC were statistically significantly related to having higher levels of HDL. Ventilatory function was unrelated to @entity101 or WC in this population. CONCLUSION: Many @entity65 risk factors are associated with poorer ventilatory function in young adults. Endeavours to understand better causality issues of such associations are warranted.

XXXX risk factors and ventilatory function: a cross-sectional study in young adults.

@entity1 :: ('9606', 'Species') :: ['women'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impaired lung function'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease', 'COPD'] @entity209 :: ('MESH:D008659', 'Disease') :: ['MS', 'metabolic syndrome'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease']
@entity65 :: (MESH:D002318,Disease) :: ['Cardiovascular disease']
