Destruction and arthroplasties of the metatarsophalangeal (MTP)joints and @entity6520 ( @entity6520 ) joint of the big toe were evaluated in 103 @entity309 ( @entity309 ) @entity1 in a prospective follow-up study at onset and at 1, 3, 8, 15, and 20 years from entry. A total of 83 @entity1 attended the 15-year follow-up and 68 attended the 20-year follow-up. Data on the forefoot synovectomies and reconstructions performed were obtained from @entity1 documents and radiographs. The radiographs were assigned by the Larsen method; in the end point analysis the last or preoperative radiograph was used. Erosions of Larsen grade > or =2 were present in 6%/ of the investigated 1236 joints at onset and after 20 years in 62%, respectively. At the end point, 24% of the joints were severely damaged (Larsen grade 4-5). The MTP I and @entity6520 joints showed the lowest grade of destruction during follow-up, and MTP V the worst destruction. Synovectomies were performed in 24 MTP joints; a total of 75% of these joints were later resected. MTP II-V head resections were performed in 21% and the Keller procedure in 12% of the MTP I joints. Erosive changes occur early in the MTP joints, and their grade of destruction is high; therefore they should be included in radiographic criteria and scores. MTP synovectomies are insufficient treatments for @entity309 without concomitant immunosuppression of the disease.

Destruction and arthroplasties of the metatarsophalangeal joints in XXXX . A 20-year follow-up study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity6520 :: ('MESH:C536223', 'Disease') :: ['interphalangeal', 'IP'] @entity309 :: ('MESH:D001172', 'Disease') :: ['seropositive rheumatoid arthritis', 'RA']
@entity309 :: (MESH:D001172,Disease) :: ['seropositive rheumatoid arthritis']
