BACKGROUND:    Intermittent screening and treatment in pregnancy (ISTp) is a potential strategy for the control of @entity311 during pregnancy. However, the frequency and consequences of @entity281 missed by a @entity1062 ( @entity1062 ) for @entity311 are a concern. METHODS:    Primigravidae and secundigravidae who participated in the ISTp arm of a noninferiority trial in 4 West African countries were screened with an @entity15279 /pLDH @entity1062 on enrollment and, in Ghana, at subsequent antenatal clinic (ANC) visits. Blood samples were examined subsequently by microscopy and by a polymerase chain reaction (PCR) assay. RESULTS:    The sensitivity of the @entity1062 to detect peripheral blood @entity281 confirmed by microscopy and/or PCR at enrollment ranged from 91% (95% confidence interval [CI], 88%, 94%) in Burkina Faso to 59% (95% CI, 48%, 70% in The Gambia. In Ghana, @entity1062 sensitivity was 89% (95% CI, 85%, 92%), 83% (95% CI, 76%, 90%) and 77% (95% CI, 67%, 86%) at enrollment, second and third ANC visits respectively but only 49% (95% CI, 31%, 66%) at delivery. Screening at enrollment detected 56% of all @entity281 detected throughout pregnancy. Seventy-five @entity1062 negative PCR or microscopy positive @entity281 were detected in 540 @entity1 ; these were not associated with maternal @entity417 , @entity311 , or low birth weight. CONCLUSIONS:    The sensitivity of an @entity1062 to detect @entity311 in primigravidae and secundigravidae was high at enrollment in 3 of 4 countries and, in Ghana, at subsequent ANC visits. In Ghana, @entity1062 negative @entity281 were not associated with adverse birth outcomes but missed @entity281 were uncommon.

The Performance of a Rapid Diagnostic Test in Detecting @entity281 in Pregnant XXXX and the Impact of Missed Infections.

@entity1 :: ('9606', 'Species') :: ['women'] @entity15279 :: ('84717', 'Gene') :: ['HRP2'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anemia'] @entity281 :: ('MESH:D007239', 'Disease') :: ['malaria infections', 'infections'] @entity1062 :: ('MESH:D013736', 'Disease') :: ['RDT', 'rapid diagnostic test'] @entity311 :: ('MESH:D008288', 'Disease') :: ['malaria', 'placental malaria']
@entity1 :: (9606,Species) :: ['Women']
