Published literature on the @entity137 of a @entity1771 @entity1445 is limited to case reports. This retrospective study of poison center data was performed to examine the severity of @entity1771 @entity1445 . Data on single substance exposures to @entity1771 reported to the American Association of Poison Control Centers (AAPCC) Toxic Exposure Surveillance System (TESS) in 2000 and 2001 were retrospectively analysed. A total of 567 cases met the inclusion criteria, of which 39% occurred in adults over 19 years of age and 30.2% in @entity1 < or = 4 years old. The majority of @entity1 (62.1%) experienced no @entity137 . The most common clinical effects reported were drowsiness/lethargy (15.5%), dizziness/vertigo (4.9%), @entity2146 (4.9%), @entity911 (3.9%), @entity390 (2.6%) and @entity391 (2.5%). Symptomatic @entity1 were older than asymptomatic @entity1 and adults were more likely to be managed in a healthcare facility (P <0.0001). @entity1 who received gastrointestinal decontamination experienced less serious outcomes than those without decontamination (P <0.02). It is concluded that clinicians should expect relatively mild mental status changes in adults or @entity1 with @entity137 from @entity1771 @entity1445 . Serious toxic effects, such as @entity308 with @entity1576 or persistent non-anion gap @entity520 , are infrequent.

Evaluation of XXXX of @entity1771 exposures reported to poison centers.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity308 :: ('MESH:D003866', 'Disease') :: ['CNS depression'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity520 :: ('MESH:D000138', 'Disease') :: ['metabolic acidosis'] @entity1771 :: ('MESH:C052342', 'Chemical') :: ['topiramate'] @entity2146 :: ('MESH:D011595', 'Disease') :: ['agitation'] @entity911 :: ('MESH:D003221', 'Disease') :: ['confusion'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory depression'] @entity1445 :: ('MESH:D062787', 'Disease') :: ['overdoses', 'overdose']
@entity137 :: (MESH:D064420,Disease) :: ['toxicity']
