UNASSIGNED: The correct pathologic classification of @entity1636 ( @entity1636 ) is relevant to establish an early therapeutic strategy of this rare malignancy. The aim of the study was to assess the most frequent pitfalls in @entity1636 diagnosis reviewing a large consecutive series of 300 cases with an original diagnosis or a clinical suspect of @entity1636 , which were sent in consultation to our institution between 2004 and 2014. A major disagreement that significantly modified the clinical management of @entity1 was recorded in 26 cases (9%). The most common pitfall (10 cases) was to distinguish @entity1636 from @entity1911 . Seven other cases diagnosed as @entity1636 were reclassified as metastases from other primaries and primary @entity8650 (including 3 @entity5426 ). Finally, 5 @entity822 were reclassified into @entity189 , and 4 ACCs were converted into @entity652 . @entity2048 were mostly related to the identification of @entity1636 variants (up to 32% of cases of @entity16663 in the present series). Moreover, more than 50% of @entity1636 cases lacked Ki-67. In conclusion, our results indicate that, in the presence of a histologically suspected @entity1636 , a special attention should be devoted to exclude metastatic and soft tissue @entity5 and @entity1911 (in this latter case with special reference to the oncocytic variant of @entity16663 ). Moreover, pathologists should be aware of the major role of Ki-67 in determining prognosis and in selecting @entity1 to the most appropriate treatment.

Pitfalls in the diagnosis of XXXX : a lesson from 300 consultation cases.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8650 :: ('MESH:D012983', 'Disease') :: ['adrenal soft tissue tumors'] @entity1911 :: ('MESH:D010673', 'Disease') :: ['pheochromocytoma', 'pheochromocytoma and vice versa'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity5426 :: ('MESH:D006394', 'Disease') :: ['angiosarcomas'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas'] @entity16663 :: ('MESH:D000306', 'Disease') :: ['adrenocortical tumors'] @entity1636 :: ('MESH:D018268', 'Disease') :: ['ACC', 'adrenocortical carcinoma'] @entity2048 :: ('MESH:D004832', 'Disease') :: ['Minor disagreements'] @entity822 :: ('MESH:D018246', 'Disease') :: ['adrenocortical adenomas'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas']
@entity16663 :: (MESH:D000306,Disease) :: ['adrenocortical tumors']
