OBJECTIVES: The potential performance of apparent diffusion coefficient (ADC) values for distinguishing @entity358 , further characterizing the @entity2 was assessed. METHODS: PubMed, EMBASE, Cochrane Library, EBSCO, and three Chinese databases were searched to identify eligible studies on diffusion-weighted imaging (DWI) of focal @entity358 . ADC values of malignant and benign lesions were extracted by lesion type and statistically pooled based on a linear mixed model. Further analysis for @entity2 was also performed. The methodological quality was assessed using the quality assessment of diagnostic accuracy studies tool. RESULTS: Thirty-four articles involving 2086 @entity1 were included. @entity358 have significantly lower ADC values than benign lesions [1.21 (95  % CI, 1.19-1.22) mm(2)/s vs. 1.76 (95  % CI, 1.72-1.80) mm(2)/s; P   <   0.05]. There is a significant difference between ADC values of @entity151 and @entity1149 (P   <   0.05), while the differences were not significant among histological subtypes of @entity2 . The methodological quality was relatively high, and the data points from Begg's test indicated that there was probably no obvious publication bias. CONCLUSIONS: The ADC value is helpful for distinguishing @entity358 and provides a promising method for differentiation of @entity4153 from NSCLC. KEY POINTS:     This meta-analysis assesses the role of DWI in @entity358 .     Differentiation and classification @entity2 is essential for treatment decision-making.     ADC values can help distinguish between malignant and benign lesions.     ADC values might help characterize the @entity2 .

Apparent diffusion coefficient values of diffusion-weighted imaging for distinguishing XXXX : a meta-analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4153 :: ('MESH:D018288', 'Disease') :: ['SCLC'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['non-small cell lung cancer'] @entity2 :: ('MESH:D008175', 'Disease') :: ['subtype of lung cancer', 'lung cancer'] @entity358 :: ('MESH:D008171', 'Disease') :: ['Malignant pulmonary lesions', 'malignant and benign pulmonary lesions', 'pulmonary lesions'] @entity151 :: ('MESH:D055752', 'Disease') :: ['small cell lung cancer']
@entity2 :: (MESH:D008175,Disease) :: ['focal pulmonary lesions and characterizing the subtype of lung cancer']
