OBJECTIVE: To better delineate the spectrum of @entity16 of primary @entity244 ( @entity244 ). METHODS: A detailed neurological investigation was prospectively performed in a group of 25 consecutive @entity1 with @entity244 followed in an internal medicine department between June 1996 and December 1997 (Internal Medicine group). In addition, eleven @entity1 with @entity16 of @entity244 were identified in the Neurological Department of the same institution during the same period (Neurological group). RESULTS: In the Internal Medicine group, @entity16 were discovered in 10/25 (40%) @entity1 . Peripheral nervous system involvement was present in 4/25 @entity1 from the Internal Medicine group and in 10/11 @entity1 from the Neurological group and consisted mainly of axonal sensorimotor/sensory @entity305 . A motor neuron syndrome was identified in two @entity1 . CNS involvement occurred in 7/25 @entity1 from the Internal Medicine group and in 4/11 @entity1 from the Neurological group. Three @entity1 had @entity602 . @entity73 was the most frequent finding (5/25 in the Internal Medicine group, 3/11 in the Neurological group) characterized either by subcortical or @entity409 . @entity73 was not attributed to mood disturbance and was not associated with specific laboratory or radiological abnormalities. CONCLUSION: @entity16 of @entity244 are frequent since they were present in 40% (10/25) of @entity1 in a consecutive series of @entity1 from a department of Internal Medicine. Although PNS involvement predominates, complications of @entity244 affecting the brain or spinal cord are not rare, with @entity409 as the main finding.

XXXX of primary @entity244 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity73 :: ('MESH:D003072', 'Disease') :: ['Cognitive dysfunction', 'Cognitive impairment'] @entity16 :: ('MESH:D009422', 'Disease') :: ['Neurological complications', 'neurological complications'] @entity602 :: ('MESH:D013118', 'Disease') :: ['spinal cord involvement'] @entity409 :: ('MESH:D008107', 'Disease') :: ['subcortical dysfunction', 'corticosubcortical dysfunction'] @entity305 :: ('MESH:D011115', 'Disease') :: ['polyneuropathy'] @entity244 :: ('MESH:D014899', 'Disease') :: ["Sj  gren's syndrome", 'PSS']
@entity16 :: (MESH:D009422,Disease) :: ['Neurological complications']
