PURPOSE: To compare the effectiveness of @entity9940 and @entity2180 in relieving ureteral stents related symptoms. @entity1 AND METHODS: A randomized controlled trial was conducted between January 2013 and July 2014. Inclusion criteria were @entity1 aged 20-50  years who underwent temporary unilateral ureteral stent for drainage of calcular upper tract obstruction or after ureteroscopic lithotripsy. @entity1 with history of lower urinary tract symptoms before stent placement, stents that were fixed after open or laparoscopic procedures, and those who developed complications related to the primary procedure were not included. Eligible @entity1 were randomly assigned to 1 of 3 groups using computer-generated random tables. @entity1 in group 1 received placebo, @entity1 in group 2 received @entity9940 0.4  mg once daily, and those in group 3 received @entity2180 5  mg once daily. Ureteral Stent Symptom Questionnaire (USSQ) was answered by all @entity1 1-2  weeks after stent placement. The primary outcome was the comparison of total score of USSQ between all groups. RESULTS: The study included 131 @entity1 . All baseline characteristics (age, sex, side, indication, length, and duration of stent) were comparable for all groups. Total USSQ score was 61 in @entity2180 group, 76 in @entity9940 group, and 83 in control group (P  <  0.001). The total USSQ scores and all domains, except sexual index, were significantly better in @entity2180 than in @entity9940 group (P  <  0.05). CONCLUSION: The use of @entity9940 alone or @entity2180 alone in @entity1 with ureteral stents can improve the quality of life by decreasing ureteral stent-related symptoms. @entity2180 was better than @entity9940 . CLINICALTRIAL. GOV IDENTIFIER: NCT01880619.

A randomized controlled trial comparing alpha blocker ( @entity9940 ) and anticholinergic ( XXXX ) in treatment of ureteral stent-related symptoms.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity2180 :: ('MESH:C441209', 'Chemical') :: ['solifenacin', 'Solifenacin'] @entity9940 :: ('MESH:C088482', 'Chemical') :: ['tamsulosin']
@entity2180 :: (MESH:C441209,Chemical) :: ['solifenacin']
