The antimicrobial susceptibilities of 76 field isolates of @entity2127 from different states of Australia were tested in a newly developed broth dilution procedure. The antimicrobial agents used were tiamulin, @entity69508 , @entity8588 , @entity2929 , @entity6186 and @entity3402 . The results from the broth dilution susceptibility testing of 39 of the isolates were compared with results obtained for the same isolates using the agar dilution method. Amongst the isolates tested by broth dilution, 17 were from three farms and had been collected over a number of years. Their pulsed field gel electrophoresis pattern previously had been determined. The broth dilution technique was simple to use, less labor intensive than agar dilution, and gave clear end points. The results obtained using the two methods generally corresponded well, although in a few cases the MIC obtained by broth dilution were lower than those with agar dilution. For the 76 isolates tested by broth dilution, the MIC(90) (mg/l) was: tiamulin, 1; valnemulin, 0.5; @entity8588 >256; erythromycin>256; @entity6186 , 64 and @entity3402 , 16. Only minor differences in susceptibility patterns were found amongst isolates from different Australian states. Over all the isolates, and also amongst the isolates obtained from different years on the three farms, there was no trend for the susceptibility of the isolates to alter with time.

Antimicrobial susceptibility testing of Australian isolates of XXXX using a new broth dilution method.

@entity8588 :: ('MESH:D015645', 'Chemical') :: ['tylosin'] @entity2929 :: ('MESH:D004917', 'Chemical') :: ['erythromycin'] @entity6186 :: ('MESH:D008034', 'Chemical') :: ['lincomycin'] @entity2127 :: ('159', 'Species') :: ['Brachyspira hyodysenteriae'] @entity69508 :: ('MESH:C117845', 'Chemical') :: ['valnemulin'] @entity3402 :: ('MESH:D002981', 'Chemical') :: ['clindamycin']
@entity2127 :: (159,Species) :: ['Brachyspira hyodysenteriae']
