OBJECTIVE: To investigate the basis of disturbed moral judgment in @entity1 with @entity4943 ( @entity4943 ). BACKGROUND: @entity4943 is characterized by difficulty in modulating social behavior. @entity1 lack social propriety and may perform sociopathic acts. In addition, @entity4943 @entity1 often lack empathy for others. These findings suggest alterations in the nature of morality in @entity1 with @entity4943 . METHOD: We administered an inventory of moral knowledge and two moral dilemmas to 26 @entity1 with the frontal variant of @entity4943 , 26 @entity1 with @entity195 ( @entity195 ), and 26 normal control subjects. The @entity4943 @entity1 met Consensus Criteria for @entity4943 and had @entity2122 on functional neuroimaging. The @entity4943 and @entity195 @entity1 were comparably impaired on @entity303 measures. RESULTS: All these groups showed the retention of knowledge for moral behavior and the ability to make "impersonal" moral judgments. In contrast, the @entity4943 @entity1 were impaired in their ability to make immediate, emotionally based moral judgments compared with the @entity1 with @entity195 and the normal control subjects. CONCLUSIONS: These findings are consistent with an attenuation of the automatic emotional identification with others that is part of the innate moral sense. Such a disturbance may result from @entity179 affecting the ventromedial frontal cortex.

An investigation of moral judgement in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2122 :: ('MESH:D019465', 'Disease') :: ['corroborative frontal abnormalities'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative disease'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', 'Alzheimer disease'] @entity4943 :: ('MESH:D057180', 'Disease') :: ['FTD', 'frontotemporal dementia']
@entity4943 :: (MESH:D057180,Disease) :: ['frontotemporal dementia']
