BACKGROUND: Posteriorly fixed @entity5 is often considered incurable, but may be resectable using transsacral approaches. METHODS: We reviewed 45 @entity1 undergoing transsacral exenteration for this problem since 1983 to determine outcome of such surgery. RESULTS: The group consisted of 38 @entity1 and 7 @entity1 ; 17 had @entity5 , 28 had recurrent @entity5 : local excision, 1; low anterior resection, 11; or abdominoperineal resection, 16. Thirty-nine had prior XRT. Operative mortality was 4%. Severe @entity158 was relieved in 16 of 22 (72%) @entity1 . Crude recurrence rates are local 22%, local plus distant 11%, distant 16%. Five-year disease-free survival is 31% for @entity66 , 32% for recurrence. Median survival is abdominoperineal resection recurrence, 24 months; primary @entity5 , 30 months; low anterior resection recurrence, 37 months. CONCLUSIONS: Transsacral exenteration relieved @entity158 in 70% of @entity1 with fixed @entity5 , and led to long-term survival in 31% to 32%. Prognosis trended toward benefit for recurrence after low anterior resection.

Transsacral exenteration of fixed primary and recurrent XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['anorectal cancer', 'primary tumors', 'cancer'] @entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity66 :: ('MESH:D004194', 'Disease') :: ['primary disease'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity5 :: (MESH:D009369,Disease) :: ['anorectal cancer']
