AIM: The objective of this study was to determine whether the baseline estimated glomerular filtration rate (eGFR) level was independently associated with in-hospital mortality in generalized @entity1 with hospital-acquired @entity810 (HA-AKI) in China. METHODS: All of the @entity1 admitted to a tertiary medical center of Nanjing, China, between January 1, 2013, and December 31, 2013, were involved. Through the use of an electronic database and the @entity810 Network (AKIN) classification, the @entity1 with HA-AKI were indentified. We included the hospitalized adult @entity1 with HA-AKI. Epidemiological information and in-hospital outcomes were collected and were analyzed according to different baseline eGFR strata of the included individual @entity1 . RESULTS: Of the 42,664 admissions during the study period, 1327 @entity1 were identified as AKI. The incidence of HA-AKI was 3.1  %. HA-AKI @entity1 with a compromised baseline eGFR tended to be older and had a higher prevalence of various comorbid conditions. With the gradual deterioration of the baseline eGFR, the odds ratio of in-hospital mortality increased incrementally and a graded independent association between the baseline eGFR and in-hospital mortality was observed when the baseline eGFR dropped below 60  ml/min per 1.73  m(2). CONCLUSION: Baseline eGFR was a potential risk factor for in-hospital mortality in HA-AKI. Serum @entity1011 (SCr)-based definition of AKI needs to incorporate baseline eGFR to optimize or refine risk stratification.

Hospital-acquired XXXX : an analysis of baseline estimated glomerular filtration rate and in-hospital mortality.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute kidney injury', 'Acute Kidney Injury'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['Creatinine']
@entity810 :: (MESH:D058186,Disease) :: ['acute kidney injury']
