Low spatial frequency (SF) processing has been shown to be impaired in @entity1 with @entity161 , but it is not clear how this varies with clinical state or illness chronicity. We compared @entity161 @entity1 (SCZ, n=34), first @entity716 @entity1 (FEP, n=22), and healthy controls (CON, n=35) on a gender/facial discrimination task. Images were either unaltered (broadband spatial frequency, BSF), or had high or low SF information removed (LSF and @entity650 conditions, respectively). The task was performed at hospital admission and discharge for @entity1 , and at corresponding time points for controls. Groups were matched on visual acuity. At admission, compared to their BSF performance, each group was significantly worse with low SF stimuli, and most impaired with high SF stimuli. The level of impairment at each SF did not depend on group. At discharge, the SCZ group performed more poorly in the LSF condition than the other groups, and showed the greatest degree of performance decline collapsed over @entity650 and LSF conditions, although the latter finding was not significant when controlling for visual acuity. Performance did not change significantly over time for any group. @entity650 processing was strongly related to visual acuity at both time points for all groups. We conclude the following: 1) SF processing abilities in @entity161 are relatively stable across clinical state; 2) face processing abnormalities in SCZ are not secondary to problems processing specific SFs, but are due to other known difficulties constructing visual representations from degraded information; and 3) the relationship between @entity650 processing and visual acuity, along with known SCZ- and medication-related acuity reductions, and the elimination of a @entity73 after controlling for visual acuity in this study, all raise the possibility that some prior findings of @entity73 in SCZ may be secondary to acuity reductions.

Processing of spatial-frequency altered faces in XXXX : effects of illness phase and duration.

@entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity650 :: ('3569', 'Gene') :: ['HSF'] @entity73 :: ('MESH:D003072', 'Disease') :: ['SCZ-related impairment', 'impaired perception'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia'] @entity716 :: ('MESH:D011605', 'Disease') :: ['episode psychosis']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
