BACKGROUND: The authors attempted to determine the incidence of and risk factors for @entity1207 in @entity1 treated for @entity2 . They also sought to describe the corresponding posttreatment radiographic changes. METHODS: Between 1989-1993, 83 @entity1 received curative radiation therapy for @entity2 . Of these, 39 @entity1 were treated with definitive radiation therapy, and 44 @entity1 were treated with adjuvant radiation therapy after surgical resection. The median radiation therapy dose was 54 gray (Gy), and the median treatment area was 182 cm2. Chest radiographs obtained after radiation therapy were reviewed and scored for margin definition, @entity393 , and texture quality. RESULTS: A total of 17 @entity1 (20%) developed @entity1207 ( @entity1207 ). The median radiation therapy dose for the @entity1207 cohort was 54 Gy, and the median treatment volume was 193 cm2. The median time to onset of symptoms was 3 weeks after radiation therapy, and the median duration of symptoms was 10 weeks. Of the 15 evaluable @entity1 , symptoms resolved for 9 @entity1 , improved but persisted for 4 @entity1 , and @entity1207 was fatal for 2 @entity1 . The incidence of @entity1207 was increased for @entity1 with low performance status, comorbid lung disease, smoking history, low pulmonary function tests, and for those @entity1 who did not undergo a surgical resection. Posttreatment radiographic changes were common and progressed with time. Radiographic changes were more pronounced in the @entity1207 cohort, and extended outside the radiation therapy treatment field in the majority of @entity1 (67%). CONCLUSIONS: @entity1207 developed in 20% of @entity2 @entity1 . Risk factors included low performance status, comorbid lung disease, smoking history, low pulmonary function tests, and the absence of a surgical resection. Posttreatment radiograph changes were common and progressed with time, and typically were not confined to the radiation therapy treatment field.

@entity1207 and radiographic changes after thoracic radiation therapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity393 :: ('MESH:D034381', 'Disease') :: ['volume loss'] @entity1207 :: ('MESH:D017564', 'Disease') :: ['Clinical radiation pneumonitis', 'CRP', 'clinical radiation pneumonitis'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung carcinoma']
@entity2 :: (MESH:D008175,Disease) :: ['lung carcinoma']
