PURPOSE: The authors report a case of retinal pigment epithelial (RPE) tear following pars plana vitrectomy ( @entity2286 ), subretinal recombinant tissue plasminogen activator (rt-PA), and intravitreal gas administration for the displacement of large submacular @entity548 . METHODS: A @entity1 with a large submacular @entity548 secondary to neovascular @entity1020 ( @entity1020 ) received a subretinal rt-PA injection and intravitreal air installation after @entity2286 . Ophthalmic examination included standardized visual acuity testing and @entity941 angiography. @entity1 : One @entity1 from the authors' outpatient clinic. RESULTS: Baseline visual acuity of the eye was 20/160. Ophthalmoscopy showed a predominantly @entity548 in the macula. Ophthalmoscopy and @entity941 angiography 2 weeks after the surgery revealed a RPE tear. Postoperative visual acuity was 20/1000. CONCLUSIONS: This case demonstrates that a RPE tear is a possible complication of the procedure of subretinal rt-PA and intravitreal air tamponade after @entity2286 for the displacement of a large submacular @entity548 secondary to neovascular @entity1020 . The surgeon has to be aware about this complication and should inform the @entity1 before surgery.

Retinal pigment epithelial tear after subretinal rtpa and intravitreal air for the displacement of a large submacular XXXX .

@entity1 :: ('9606', 'Species') :: ['patient', 'PATIENTS'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhagic lesion', 'hemorrhage'] @entity2286 :: ('12211', 'Species') :: ['PPV'] @entity941 :: ('MESH:D019793', 'Chemical') :: ['fluorescein'] @entity1020 :: ('MESH:D008268', 'Disease') :: ['AMD', 'age-related macular degeneration']
@entity548 :: (MESH:D006470,Disease) :: ['hemorrhage']
