OBJECTIVE: To study a controversy that has been discussed for more than two decades: whether or not @entity1 with @entity2438 have abnormalities affecting the cochlear nerve or the auditory pathway in the brain stem and, if so, to describe these abnormalities. DESIGN: A group of 153 @entity1 and adolescents with @entity2438 were included in an investigation of auditory brain stem responses (ABR). Two thirds of this group, 101 individuals (75 @entity1 , 26 @entity1 ), had normal hearing and they were selected for an in-depth ABR study. The results from the study group were compared with those of an age-matched comparison group. RESULTS: The III-V interpeak latency (IPL) was significantly prolonged in both @entity1 and @entity1 with @entity2438 , compared with the controls. The latencies of ABR waves I and V were also significantly lengthened in the study groups. The individual test results showed that more than half of this normal-hearing @entity2438 group (58%) had abnormalities of one or more of eight ABR parameters studied. The most common abnormalities were prolongation of wave V (38%), and of I-V IPL (28%). A lengthening of the I-V IPL was also recorded in 27% of 49 @entity1 who were difficult to test or who had @entity393 . Abnormal left-right differences of ABR latencies were found in 18% of @entity2438 cases with normal hearing. CONCLUSIONS: Possible causes of the reported ABR abnormalities, observed here as well as in other studies, are discussed. Brain stem lesion, occult cochlear dysfunction, and involvement of the cochlear efferent system are probable factors that can explain the ABR findings

XXXX and auditory brain stem responses.

@entity1 :: ('9606', 'Species') :: ['children', 'girls', 'boys'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss'] @entity2438 :: ('MESH:D001321', 'Disease') :: ['autistic disorder', 'autism']
@entity2438 :: (MESH:D001321,Disease) :: ['Autism']
