PURPOSE: To study the symmetry in response to bilateral @entity6 ( @entity6 ) treated with bilateral intravitreal injections of ranibizumab (IVR). METHODS: The charts of 36 eyes of 18 @entity1 treated with a loading dose of three monthly IVR in both eyes were retrospectively reviewed. Favourable anatomical response was defined as a decrease by more than 10% in baseline @entity1020 ( @entity1020 ), and favourable functional response was defined as an increase in visual acuity (VA) >= 5 letters. A symmetric response was defined as a similar anatomical and/or functional response in the first (FE) and @entity1605 ( @entity1605 ) treated eyes. RESULTS: The VA improved significantly after ranibizumab treatment in both eyes (p  <  0.01). A statistically significant positive correlation was found for the functional response to ranibizumab between the FE and the @entity1605 (R(2)   =  0.26, p  =  0.03). The mean @entity1020 decreased significantly in both eyes (p  <  0.01). A strong positive correlation was observed between the anatomical response to ranibizumab in the FE and the @entity1605 (R(2)   =  0.37, p  =  0.01). Symmetric favourable anatomical and functional responses were observed in 13 @entity1 (72%). In two additional @entity1 , an asymmetric functional response was observed despite a @entity2479 . CONCLUSION: Symmetric anatomical and functional responses were observed in 72% of @entity1 with @entity6 after three initial IVR in each eye. This finding could be of clinical interest in the decision to treat the fellow eye, in a disease where a bilateral involvement is frequent.

Symmetry in early response to intravitreal ranibizumab in bilateral XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1605 :: ('OMIM:217000', 'Disease') :: ['SE', 'second'] @entity6 :: ('MESH:D003920', 'Disease') :: ['DME', 'diabetic macular oedema'] @entity2479 :: ('MESH:D012173', 'Disease') :: ['decrease in retinal thickness in both eyes'] @entity1020 :: ('MESH:D008268', 'Disease') :: ['CMT', 'central macular thickness']
@entity6 :: (MESH:D003920,Disease) :: ['diabetic macular oedema']
