Two postoperative cardiopulmonary bypass @entity1 who had @entity788 within a two week period provided the impetus for pursuing this study. Amylase- @entity1011 clearance ratios (ACCR) were measured in a series of ten thoracic surgery @entity1 : six coronary artery bypass @entity1 with cardiopulmonary bypass (cardiac group), and four exploratory thoracotomy @entity1 (pulmonary group). These ratios were obtained in the preoperative, recovery room, and postoperative periods. Comparisons were made among the following data: clinical history, pre- and postoperative medications, intraoperative vital signs, drugs, and anesthetics. The preoperative mean ACCR was 3.34 per cent. All cardiac @entity1 had a significantly elevated ACCR in the recovery room with a mean of 17.36 per cent (p less than 0.05). The ACCR had returned to preoperative levels by the second postoperative day in five of six cases. There were no elevated ACCR levels in the pulmonary group. All @entity1 were asymptomatic for @entity788 . The intraoperative course of the cardiac @entity1 involved four common factors, besides cardiopulmonary bypass, which were not present in the pulmonary group. These similarities included transfusion of citrated fresh whole blood activated by @entity12374 , @entity551 treated with @entity6358 , administration of @entity2656 , and intraoperative @entity1286 @entity1337 . The mechanisms of increased amylase secretion by @entity12374 or @entity6358 administration and transient sphincter of Oddi constriction by @entity1286 or the alpha-adrenergic response of @entity6358 are considered with the theoretical implications toward @entity788 . The background and significance of the ACCR are also analyzed, especially in association with the osmotic diuresis of @entity2656 and a subsequent low urine @entity1011 level.

Eelvated postoperative renal clearance of amylase without XXXX after cardiopulmonary bypass.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2656 :: ('MESH:D008353', 'Chemical') :: ['mannitol'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatitis'] @entity6358 :: ('MESH:D004809', 'Chemical') :: ['ephedrine'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity12374 :: ('MESH:D002122', 'Chemical') :: ['calcium chloride'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension']
@entity788 :: (MESH:D010190,Disease) :: ['pancreatitis']
