OBJECTIVE: To compare the clinical value of sacroiliac spectral CT and MRI in diagnosing @entity1691 (SpA). METHODS: 137 @entity1 with @entity1643 and suspected axial SpA were recruited. 76 @entity1 were diagnosed with axial SpA, and 49 @entity1 were diagnosed with non-specific @entity1643 ( @entity38899 ). Each @entity1 underwent spectral CT and MRI examinations of the @entity2720 . Water- and @entity460 -based material decomposition images were reconstructed for quantitative analysis. The marrow-to-muscle ratios of water and @entity460 concentrations and short tau inversion recovery (STIR) signal intensity, as well as Hounsfield units in the ilium and sacrum were compared between @entity38899 and @entity1 with axial SpA. RESULTS: Spectral CT is comparable with MRI for the detection of @entity236 , and it is superior to MRI for detection of @entity1463 and @entity2681 . MRI is superior to spectral CT in detecting enthesitis and @entity603 . There were statistically significant differences in STIR signal intensity, water concentration and @entity460 concentration ratios as well as CT values between @entity38899 and @entity1 with axial SpA (p   <   0.05) in the ilium. There was a statistically significant but weak correlation between ratios of water concentration and STIR signal intensity in both the ilium and sacrum (p   <   0.05). Overall, the iliac water concentration was most sensitive for detection of @entity1 with SpA. The positive likelihood ratio of the STIR signal intensity ratio was the highest. The diagnostic odds ratio of the @entity460 concentration ratio was the highest, and its negative likelihood ratio was the lowest. CONCLUSION: Spectral CT not only depicts findings of chronic @entity6592 (i.e. @entity79 and @entity1463 ), but also can detect and quantify the extent of @entity4 in @entity1 with SpA with activity @entity6592 . The sensitivity of MRI for diagnosis of @entity603 and enthesitis remains superior. The combination of spectral CT and MRI may thus improve diagnostic accuracy in the diagnosis of axial SpA. Advances in knowledge: Spectral CT can measure both @entity460 and water concentration of the @entity2720 . The combination of spectral CT and MRI may thus improve diagnostic accuracy in the diagnosis of axial SpA.

Comparing the diagnostic utility of sacroiliac spectral CT and MRI in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1643 :: ('MESH:D017116', 'Disease') :: ['low back pain'] @entity6592 :: ('MESH:D058566', 'Disease') :: ['sacroiliitis'] @entity38899 :: ('23376', 'Gene') :: ['nLBP'] @entity2681 :: ('MESH:D014077', 'Disease') :: ['erosions'] @entity4 :: ('MESH:D004487', 'Disease') :: ['marrow oedema'] @entity603 :: ('MESH:D013585', 'Disease') :: ['synovitis', 'early synovitis'] @entity1463 :: ('MESH:D012598', 'Disease') :: ['osseous sclerosis', 'sclerosis'] @entity1691 :: ('MESH:D013167', 'Disease') :: ['axial spondyloarthritis'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone erosion'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity2720 :: ('MESH:D007592', 'Disease') :: ['sacroiliac joints'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow oedema']
@entity1691 :: (MESH:D013167,Disease) :: ['axial spondyloarthritis']
