OBJECTIVE: The role of @entity66 in @entity303 in older @entity1 has been the subject of controversy. This study was undertaken to examine the prevalence of @entity455 in a prospective autopsy series of @entity1 with clinically diagnosed @entity303 . DESIGN: Structured review of clinical and neuropathological examinations. Clinical diagnoses were assigned in accordance with the recommendations of the NINCDS/ADRDA consensus panel. Neuropathological examinations were performed at an academic neuropathology service using published consensus criteria for the diagnosis of @entity195 and other forms of @entity303 . SETTING: A subspecialty, outpatient @entity303 clinic in a university-affiliated suburban American hospital. @entity1 : Eighty-seven unselected @entity1 coming to autopsy who had undergone clinical @entity303 evaluation. RESULTS: @entity303 could not be attributed to the effects of @entity66 alone in any of the 87 @entity1 coming to autopsy. Seventy-six (87%) of the @entity1 were found to have @entity195 ( @entity195 ), 44 had @entity195 alone, and 32 had @entity195 in combination with @entity66 ( @entity66 ). All of the @entity1 with signs of @entity66 at autopsy were also found to have some @entity179 . The absence of @entity1 in whom @entity1294 could be diagnosed at neuropathology was not the result of recruitment bias. CONCLUSION: Clinicians should maintain a high index of suspicion of @entity195 or other neurodegenerative process in older @entity1 whose presenting complaint is @entity303 , even in the presence of well documented @entity66 .

Absence of @entity1294 in an autopsy series from a XXXX clinic.

@entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS', 'people'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular disease'] @entity66 :: ('MESH:D004194', 'Disease') :: ['CVD', 'cerebrovascular disease'] @entity303 :: ('MESH:D003704', 'Disease') :: ['Dementia', 'dementia'] @entity1294 :: ('MESH:D015140', 'Disease') :: ['vascular dementia'] @entity179 :: ('MESH:D019636', 'Disease') :: ['concomitant neurodegenerative disease'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"]
@entity303 :: (MESH:D003704,Disease) :: ['dementia']
