BACKGROUND: @entity1 with @entity712 and reduced ejection fraction are at increased risk of @entity943 . @entity737 ( @entity737 ) is recommended to prevent @entity1164 in some of these @entity1 . @entity387 ( @entity387 ) is highly prevalent in this population and may impact arrhythmogenicity. We performed a systematic review and meta-analysis of prospective studies that assessed the impact of @entity387 on @entity737 therapy. METHODS AND RESULTS: Relevant prospective studies were identified in the Ovid MEDLINE, EMBASE, and Google Scholar databases. Weighted risk ratios of the association between @entity387 and appropriate @entity737 therapies were estimated using random effects meta-analysis. Nine prospective cohort studies (n=1274) were included in this analysis. @entity387 was present in 52% of the @entity1 . @entity387 was associated with a 55% higher risk of appropriate @entity737 therapies (45% versus 28%; risk ratio, 1.55; 95% confidence interval, 1.32-1.83). In a subgroup analysis based on the subtypes of @entity387 , the risk was higher in both central (risk ratio, 1.50; 95% confidence interval, 1.11-2.02) and obstructive (risk ratio, 1.43; 95% confidence interval, 1.01-2.03) sleep @entity386 . CONCLUSIONS: @entity387 is associated with an increased risk of appropriate @entity737 therapy in @entity1 with @entity712 and reduced ejection fraction.

Effect of Sleep-Disordered Breathing on Appropriate Implantable Cardioverter-Defibrillator Therapy in @entity1 With XXXX : A Systematic Review and Meta-Analysis.

@entity1 :: ('9606', 'Species') :: ['participants', 'Patients', 'patients'] @entity1164 :: ('MESH:D016757', 'Disease') :: ['sudden cardiac death'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity387 :: ('MESH:D012891', 'Disease') :: ['Sleep-disordered breathing', 'SDB'] @entity737 :: ('MESH:D057873', 'Disease') :: ['Implantable cardioverter-defibrillator', 'ICD'] @entity943 :: ('MESH:D001145', 'Disease') :: ['malignant ventricular arrhythmias'] @entity386 :: ('MESH:D001049', 'Disease') :: ['apnea']
@entity712 :: (MESH:D006333,Disease) :: ['Heart Failure']
