PURPOSE: This study was performed to evaluate the structure-function relationship between Bruch's membrane opening (BMO) parameters of the optic nerve head (ONH) and @entity227 ( @entity227 ) sensitivity. METHODS: Forty-six right eyes of 46 @entity1 with @entity1538 ( @entity1538 ) in the @entity1 group and 12 right eyes in the control group were included. Standard automated perimetry (SAP) and spectral-domain optical coherence tomography (SD-OCT) were assessed. Three BMO-based distances and two areas of the neuroretinal rim were used for correlation: the minimum rim width (MRW), the perpendicular rim width (PRW), the horizontal rim width (HRW), the minimum rim area (MRA) within the neuroretinal tissue defined by the MRW, and the perpendicular rim area (PRA) within the neuroretinal tissue defined by the PRW. These parameters were correlated with global and sectoral @entity227 sensitivities. Spearman's correlation coefficients between BMO parameters and global and sectoral @entity227 sensitivities were obtained. RESULTS: Within the @entity1 group, significant correlations could be observed between global and sectoral @entity227 sensitivities and BMO parameters, with PRW and PRA showing the highest values. In the sectoral analysis the highest correlations were found for the temporal-inferior @entity227 sector ( @entity601 ): PRW-TI (   = 0.72394; P < 0.00001) and PRA-TI (   = 0.77205; P < 0.00001). Minimum rim width and MRA performed more weakly than PRW and PRA. CONCLUSIONS: The BMO-based parameters PRW and PRA presented with a very good structure-function relationship in @entity726 @entity1 , statistically at least equal to MRW and MRA. Using new BMO-based parameters might allow early objective assessments of functional @entity73 .

Structure-Function Relationship Between Bruch's Membrane Opening-Based Optic Nerve Head Parameters and Visual Field Defects in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual field', 'VF'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open-angle glaucoma', 'OAG'] @entity73 :: ('MESH:D003072', 'Disease') :: ['glaucomatous impairments'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity601 :: ('MESH:D009436', 'Disease') :: ['MD-TI']
@entity726 :: (MESH:D005901,Disease) :: ['Glaucoma']
