We hypothesized that the change in aortic elastic properties could directly be shown with color Doppler tissue imaging (CDTI), that these findings could be related to @entity2333 and distensibility and that, through these, @entity453 ( @entity453 ) could be predicted. One hundred and twenty six @entity1 (group I: 83 with @entity453 , mean age 54+/-10 years, 18 female, 65 male; group II: 43 without @entity453 , mean age 53+/-10 years, 27 female, 16 male) having been evaluated for @entity453 by angiography were examined by echocardiography. Arterial pressure was measured immediately before echocardiographic evaluation. Internal aortic systolic and diastolic diameters by M-mode echocardiography and aortic upper wall tissue velocities (Aortic S, E, A, m/sec) by CDTI were measured 3 cm above the aortic valve. Lateral mitral annulus tissue velocities (Annulus S, E, A, m/sec) were also recorded. Aortic distensibility (cm2 x dynes(-1)) and @entity2333 index were calculated using formulas. In the statistical analyses, @entity453 risk factors and left ventricular ejection fraction were used for adjustment. @entity2333 (2.79+/-3.49 vs 1.62+/-1.31, P=0.03), distensibility (1.55+/-1.46 vs 2.37+/-3.08, P=0.04), and aortic S velocity (0.057+/-0.016 vs 0.064+/-0.015, P=0.02) differed significantly between groups I and II. After adjustment, while @entity2333 and S velocity were still statistically different (P=0.04; P=0.03 respectively), the significance of the difference in aortic distensibility disappeared (P=0.051). @entity2333 and aortic S velocity (0.06 m/sec<) were important @entity453 determinants (Odds ratio=1.4 P=0.03; Odds ratio=3.6 P=0.01, respectively), but aortic distensibility was not. @entity2333 was correlated only with aortic S velocity (r=-0.28, P=0.01), and aortic distensibility had a significantly positive correlation with aortic S velocity (r=0.20, P=0.02). The interobserver and intraobserver correlation coefficients for aortic S velocities were 0.65 and 0.71, respectively (P<0.05). Elastic properties of the aorta can directly be assessed by reproducibly measuring the movements in the upper wall of the aorta by CDTI. Reduced aortic S velocity is associated with increased @entity2333 . Increased @entity2333 and reduced aortic S velocity are important predictors of @entity453 .

Color Doppler tissue imaging in assessing the elastic properties of the aorta and in predicting XXXX .

@entity2333 :: ('MESH:D001018', 'Disease') :: ['aortic stiffness', 'Aortic stiffness'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'coronary artery disease'] @entity1 :: ('9606', 'Species') :: ['patients']
@entity453 :: (MESH:D003324,Disease) :: ['coronary artery disease']
