OBJECTIVES: To evaluate the efficacy of low-intensity shock wave therapy and to identify the predictive factors of its efficacy in Japanese @entity1 with @entity323 . METHODS: The present study included 57 @entity1 with @entity323 who satisfied all the following conditions: more than 6-months history of @entity323 , sexual health inventory for @entity1 score of <=  12 without phosphodiesterase type-5 inhibitor, erection @entity3358 score grade 1 or 2, mean penile circumferential change by erectometer assessing sleep related erection of < 25 mm and non-neurological pathology. @entity1 were treated by a low-energy shock waves generator (ED1000; Medispec, Gaithersburg, @entity601 , USA). A total of 12 shock wave treatments were applied. Sexual health inventory for @entity1 score, erection @entity3358 score with or without phosphodiesterase type-5 inhibitor, and mean penile circumferential change were assessed at baseline, 1, 3 and 6 months after the termination of low-intensity shock wave therapy. RESULTS: Of 57 @entity1 who were assigned for the low-intensity shock wave therapy trial, 56 @entity1 were analyzed. @entity1 had a median age of 64 years. The sexual health inventory for @entity1 and erection @entity3358 score (with and without phosphodiesterase type-5 inhibitor) were significantly increased (P < 0.001) at each time-point. The mean penile circumferential change was also increased from 13.1 to 20.2 mm after low-intensity shock wave therapy (P < 0.001). In the multivariate analysis, age and the number of concomitant comorbidities were statistically significant predictors for the efficacy. CONCLUSIONS: Low-intensity shock wave therapy seems to be an effective physical therapy for @entity323 . Age and comorbidities are negative predictive factors of therapeutic response.

Impact of aging and comorbidity on the efficacy of low-intensity shock wave therapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity323 :: ('MESH:D007172', 'Disease') :: ['erectile dysfunction'] @entity3358 :: ('MESH:D018804', 'Disease') :: ['hardness'] @entity601 :: ('MESH:D009436', 'Disease') :: ['MD']
@entity323 :: (MESH:D007172,Disease) :: ['erectile dysfunction']
