BACKGROUND AND OBJECTIVES: Limb-sparing surgery has become the preferred surgical treatment of @entity3478 . The objective of this study was to evaluate factors that influence the morbidity and outcome of prosthetic knee replacement after resection of @entity5 of the distal femur. METHODS: Eighty-two @entity1 who had a resection of @entity5 of the distal femur and implantation of a segmental knee prosthesis (minimum follow-up, 2 years) were retrospectively reviewed. RESULTS: Twenty-nine @entity1 (35%) underwent 32 prosthetic revisions, 6 from perioperative wound complications, 13 from @entity1349 , and 13 from other complications. The 3-, 5-, and 10-year Kaplan-Meier prosthetic survival rates were 82%, 71%, and 50%, respectively. On univariate analysis, @entity1 who had more than 40% resection of the distal femur (P = 0.010) and those who had all their vasti muscles resected (P = 0.011) had significantly worse prosthetic survivals than the others. On multivariate analysis, resection of more than 40% of the distal femur was a significant negative prognostic factor for prosthetic survival (P = 0.017). @entity1349 was the primary cause of late prosthetic failure. Differences in the magnitude of resection influenced prosthetic survivorship more than prosthetic design. CONCLUSIONS: In the distal femoral endoprosthetic replacement, higher short- and long-term complications were found after extensive resections. @entity1349 was the primary cause of prosthetic failure.

Relationship between magnitude of resection, complication, and prosthetic survival after prosthetic knee reconstructions for distal femoral XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['malignant tumors', 'malignant tumor'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['aseptic loosening', 'Aseptic loosening'] @entity3478 :: ('MESH:D001859', 'Disease') :: ['malignant bone tumors']
@entity5 :: (MESH:D009369,Disease) :: ['tumors']
