BACKGROUND: Although surgical resection of @entity420 or @entity957 of the esophagus is standard practice, the treatment strategy for other malignant rare @entity418 is still under debate. The aim of this study was to examine the treatment of rare @entity418 and to evaluate the survival of these @entity1 . METHODS: A retrospective review of all esophagectomies performed at Mayo Clinic from 1980 to 2014 (approximately 4,000 cases) identified 24 @entity1 with histologic features other than @entity420 or @entity957 . Their medical records were reviewed for demographics, presenting symptoms, evaluation, surgical management, pathologic features, and short-term and long-term outcome. RESULTS: Pathologic identifications included @entity4153 , @entity706 , and undifferentiated @entity189 in 4 (16.7%) @entity1 each and neuroendocrine, @entity320 , @entity1822 , sarcomatoid, @entity242 , and @entity674 in 2 (8.3%) @entity1 each. The most common presenting symptoms included @entity2026 in 91.7% @entity1 (22/24), @entity158 in 75.0% (18/24), and @entity353 in 62.5% (15/24). Preoperative evaluation included barium swallow in 91.7% (22/24), computed tomography in 91.7% (22/24), positron emission tomography in 54.2% (13/24), esophagogastroduodenoscopy in 100% (24/24), and endoscopic ultrasonography in 29.2% (7/24) @entity1 . The location of the @entity5 was at the gastroesophageal junction in 41.7% (10/24). There was no operative mortality, and 13 @entity1 (54.16%) had at least one postoperative adverse event. The 1-year survival after esophagectomy was 69.7%, the 5-year survival was 42.7%, and the 10-year survival was 37.4%. CONCLUSIONS: @entity418 with pathologic features other than @entity957 or @entity420 is rare. Esophagectomy for rare types of @entity418 should be considered part of the effective treatment paradigm.

Surgical Resection of Rare XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4153 :: ('MESH:D018288', 'Disease') :: ['small cell carcinoma'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity1822 :: ('MESH:D007890', 'Disease') :: ['leiomyosarcoma'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['dysphasia'] @entity418 :: ('MESH:D004938', 'Disease') :: ['malignant esophageal cancers', 'esophageal cancers', 'Esophageal cancer'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity674 :: ('MESH:D046152', 'Disease') :: ['gastrointestinal stromal tumor'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma']
@entity418 :: (MESH:D004938,Disease) :: ['Esophageal Cancers']
