We reviewed 33 @entity1 with 37 wounds treated between November of 1991 and December of 1995 in the Wound Care Center. A two-stage debridement and closure technique for @entity1411 was performed. @entity1 selected included those with obvious @entity4034 and those who had failed nonsurgical treatment. The approach included initial surgical excision of the @entity1066 with biopsy, bone resection with biopsy, and deep culture. The second-stage procedure 4 to 8 days later included debridement of the wound and delayed closure. Intravenous antibiotic treatment using a central line was given postoperatively in @entity1 with documented @entity4034 for at least 6 weeks and in @entity1 with infected soft tissues only for about 4 weeks. All @entity1 remained nonweightbearing for 4 weeks; this was felt necessary to prevent separation of the wound edges. Four wounds in four @entity1 failed to heal, and two of these went on to amputation. Satisfactory healing occurred in 29 of 33 @entity1 and in 33 of 37 wounds. The authors conclude that two-stage surgical debridement and closure is an acceptable treatment in selected nonhealing @entity4760 .

Treatment of XXXX with two-stage debridement and closure.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer'] @entity4034 :: ('MESH:D010019', 'Disease') :: ['osteomyelitis'] @entity1411 :: ('MESH:D016523', 'Disease') :: ['neuropathic foot ulcers'] @entity4760 :: ('MESH:D017719', 'Disease') :: ['diabetic (neuropathic) foot ulcers']
@entity4760 :: (MESH:D017719,Disease) :: ['diabetic (neuropathic) foot ulcers']
