Objective To analyze the survival rate of a nonselected pyriform sinus @entity5 population. Study Design Case series with chart review. Setting University hospital. Subjects and Methods A total of 122 @entity1 were included in this study covering the 2002-2008 period. All @entity1 had @entity957 originating from the pyriform sinus. Survival and prognostic factors were analyzed. Results The 3- and 5-year overall survival rates were 39.7% and 2.4%, respectively. The 3- and 5-year survival rates without recurrence were 34% and 27%, respectively. The median survival rates by UICC stage were as follows: stage 1 and 2 @entity1 , 60 months; stage 3, 40 months; stage 4, 19 months. Stage 4 @entity1 had a lower median survival rate than other stages ( P = .039). The 5-year survival rate was 46% for @entity1 having T3-T4 operable @entity5 treated by surgery vs 45% for @entity1 treated by laryngeal conservation protocol (not significant). The 5-year survival rate for @entity1 having nonoperable T4 @entity5 was 17.2%. The 3- and 5-year overall survival rates of N0 @entity1 was significantly higher than N1 @entity1 ( P = .042). N2 and N3 @entity1 had 100% 5-year mortality. Conclusion This study showed that overall survival and therapeutic management depend on the @entity5 , notably on the N status. In particular, nonoperable T4 pyriform sinus @entity5 and N2 and N3 @entity1 had a very poor prognosis. A laryngeal conservation protocol seemed as effective as surgical management in terms of survival.

Therapeutic Management of Pyriform XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'initial stage of pyriform sinus cancer', 'cancer'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['Sinus Cancer']
