BACKGROUND: Although @entity697 is the most common cause for abdominal surgery in @entity1 , its etiology is still largely unknown. The aim of this study was to evaluate the role of bacterial and viral pathogens for the etiology of @entity698 in @entity1 . METHODS: Between 2000 and 2010, 277 @entity1 underwent appendectomy in our institution. On this collective, a retrospective study was performed on to identify the presence of bacterial or viral pathogens. RESULTS: Intraoperatively, 39% of cases showed acute, 9% of cases chronic, and 41% of cases @entity32 . Bowel perforation was found in 7% of cases and four percent of the @entity1 had no @entity32 of the appendix at all. @entity526 was the predominant bacterium with an incidence of 27.4%, followed by streptococci (9.8%). Concerning viral pathogens, adenovirus was the most common with an incidence of 5.4% followed by rotavirus (4.7%). Significant correlations between histopathological findings and present pathogens were found: in cases of bowel perforation there were significantly more infections with @entity526 bacteria (32.2%, p < .001), streptococci (12.2%, p < 0.001), and @entity796 (6.7%, p < .001) whereas chronic @entity32 were accompanied with a significantly elevated rate of @entity2550 (2.5%, p = .016). Acute @entity32 were significantly more often associated with campylobacter (1.7%, p = .011) and oxyures infections (6.1%, p < .001). In relation to the @entity1 ' age, a significant accumulation of different pathogens was observed. CRP- and leukocyte counts showed differences between viral and bacterial @entity32 . CONCLUSIONS: Our data indicates that @entity698 in @entity1 might be triggered by bacterial and viral pathogens and that the type of pathogen directly correlates with @entity1 age, type of @entity32 , and level of @entity32 values. To confirm and further evaluate these findings, additional studies need to be conducted.

Etiology of @entity698 in XXXX : The Role of Bacterial and Viral Pathogens.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['ulcerous inflammation', 'inflammation', 'inflammations'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute appendicitis'] @entity796 :: ('287', 'Species') :: ['Pseudomonas aeruginosa'] @entity698 :: ('MESH:D001064', 'Disease') :: ['appendicitis'] @entity2550 :: ('MESH:D015009', 'Disease') :: ['yersinia infections'] @entity526 :: ('562', 'Species') :: ['Escherichia coli', 'E. coli']
@entity1 :: (9606,Species) :: ['Children']
