OBJECTIVE: Estimating the risk entailed by classical risk factors like blood pressure (BP) or serum @entity165 may be difficult because of their variability and the often unknown duration of exposure. Having variables integrating the impact of those classical risk factors on the cardiovascular system would probably aid the prediction of cardiovascular events. The present study aimed at determining whether @entity299 ( @entity4375 ), correlates with several risk factors and thus is a good candidate for being such an integrative variable. As a comparison, left ventricular mass (LVM), pulse wave velocity ( @entity122 ), and @entity1011 were also tested for association with risk factors. DESIGN: A total of 302 subjects referred for @entity101 , were considered. They had a 24-h BP recording and a determination of @entity4375 by two different methods (sequence and alpha coefficient), in two different positions (lying and standing). They were also tested for the presence of @entity4346 ( @entity4346 ) (by echocardiography and electrocardiogram) and had a @entity122 measurement. Biological testing included serum lipids, blood @entity413 , @entity1011 , @entity644 and urinary excretion of microalbumin. RESULTS: There was a strong correlation between the two methods of @entity4375 measurement in each position (P < 0.001). @entity4375 determined by the sequence method in the lying position was correlated significantly and independently with age, 24-h systolic BP, heart rate, and serum @entity165 with P values < 0.001, < 0.001, < 0.01, and < 0.05, respectively. In an univariate analysis, @entity4375 was also correlated with echocardiographic LVM index (r = -0.21, P < 0.05) and @entity122 (r = -0.27, P < 0.001), which possibly reflects its dependence on both vascular and @entity299 . CONCLUSION: The present study supports the hypothesis that @entity4375 could encompass the impact over time of several risk factors on the cardiovascular system. Thus, it may constitute a valuable parameter in assessing more precisely the risk of cardiovascular events.

Spontaneous baroreflex sensitivity: toward an ideal index of cardiovascular risk in XXXX ?

@entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity4375 :: ('11246', 'Species') :: ['BRS'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['LVH', 'left ventricular hypertrophy'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac baroreflex sensitivity', 'cardiac damages'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity122 :: ('31732', 'Species') :: ['PWV']
@entity101 :: (MESH:D006973,Disease) :: ['hypertension']
