UNASSIGNED: Due to their inherent @entity6337 and inevitable environmental release, @entity6701 nanoparticles (nano- @entity3759 ) are increasingly studied in the field of aquatic toxicology. One of the particular interests is the interactions between nano- @entity3759 and natural organic matter (NOM). In this study, a series of experiments was conducted to study the impacts of Suwannee River natural organic matter (SRNOM) on @entity6337 and particle behaviors of nano- @entity3759 . For Daphnia magna, after the addition of 5mg/L SRNOM, LC50 value decreased significantly from 1.03 (0.89-1.20) mg/L to 0.26 (0.22-0.31) mg/L. For @entity3392 larvae, phototoxic LC50 values were 39.9 (95% CI, 25.9-61.2) mg/L and 26.3 (95% CI, 18.3-37.8) mg/L, with or without the presence of 5mg/L SRNOM, respectively. There was no statistically significant change of these LC50 values. The impact of SRNOM on @entity6337 of nano- @entity3759 was highly dependent on test species, with D. magna being the more sensitive species. The impact on particle behavior was both qualitatively and quantitatively examined. A global predictive model for particle behavior was developed with a three-way interaction of SRNOM, @entity3759 concentration, and time and an additive effect of ionic strength. Based on power analyses, 96-h exposure in bioassays was recommended for nanoparticle-NOM interaction studies. The importance of reactive @entity26 species (ROS) quenching of SRNOM was also systematically studied using a novel exposure system that isolates the effects of environmental factors. These experiments were conducted with minimal impacts of other important interaction mechanisms (NOM particle stabilization, NOM UV attenuation, and NOM photosensitization). This study highlighted both the particle stabilization and ROS quenching effects of NOM on nano- @entity3759 in an aquatic system. There is an urgent need for representative test materials, together with key environmental factors, for future risk assessment and regulations of nanomaterials.

Impact of natural organic matter on particle behavior and @entity6337 of XXXX nanoparticles.

@entity6337 :: ('MESH:D017484', 'Disease') :: ['phototoxicity'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity3759 :: ('CHEBI:32234', 'Chemical') :: ['TiO2'] @entity6701 :: ('MESH:C009495', 'Chemical') :: ['titanium dioxide'] @entity3392 :: ('7955', 'Species') :: ['zebrafish']
@entity6701 :: (MESH:C009495,Chemical) :: ['titanium dioxide']
