BACKGROUND: The aims of this work were (a) to evaluate the prevalence of @entity66 ( @entity66 ) in a large sample of the Brazilian general population and (b) to compare @entity66 prevalence between @entity1 and adults. METHODS: The study group comprised 4405 subjects (2629 F and 1776 M). Age distributions were 2034 (1-14 years), 848 (15-29), 584 (30-44), 667 (45-59) and 272 above 60. The immunoglobulin A antiendomysial antibody (IgA-EMA) test was used as the serological screening tool. All sera were submitted to turbidimetric measurement of IgA levels and those with @entity7491 to the IgG antigliadin (IgG-AGA) test. The small intestinal biopsy was recommended for subjects showing either (a) IgA-EMA positivity or (b) selective @entity7491 (SigAD) and IgG-AGA positivity. RESULTS: There were 16 EMA positive out of 4405 sera tested. SigAD was found in five cases (one adult and four @entity1 ). Two of these @entity1 tested positive for IgG-AGA and underwent jejunal biopsy that, in both cases, disclosed a normal mucosa. Overall, 17 out of 18 eligible subjects performed the small intestinal biopsy. The prevalence of biopsy-proven @entity66 in this study group was 3.41 per 1000 individuals. If all 18 EMA-positive @entity1 were included, the overall prevalence would become 3.63 per 1000. The prevalence in adults and @entity1 was 2.11 per 1000 and 5.44 per 1000, respectively. CONCLUSION: This work supports previous findings showing that @entity66 is not a @entity395 in Brazil and that there is an unexplained difference in the prevalence of @entity66 between adults and @entity1 .

Prevalence of XXXX : unexplained age-related variation in the same population.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity7491 :: ('MESH:D017098', 'Disease') :: ['IgA deficiency'] @entity395 :: ('MESH:D035583', 'Disease') :: ['rare disorder'] @entity66 :: ('MESH:D004194', 'Disease') :: ['coeliac disease', 'CD']
@entity66 :: (MESH:D004194,Disease) :: ['coeliac disease']
