OBJECTIVES: This study investigated whether @entity583 @entity1 with @entity6 had lower heart rate reserve to exercise by measuring the increment in heart rate (HR) divided by the increment of @entity1063 (NE) concentration from rest to peak exercise (delta HR/log delta NE). The difference in exercise training effects was also investigated. METHODS: The 148 @entity1 after @entity583 were divided into two groups, the @entity3918 group (n = 34) and the non- @entity3918 group (n = 114). Cardiopulmonary exercise testing was performed in each subject at 1 and 3 months after the onset. Blood samples were taken at rest and immediately after peak exercise, rest brain natriuretic peptide, rest and peak @entity1063 were analyzed. Exercise training was performed from 1 to 3 months after the onset. RESULTS: Resting heart rates were significantly higher in the @entity3918 group than in the non- @entity3918 group both at 1 and 3 months although peak heart rates were not significantly different. Peak @entity26 uptake were lower in the @entity3918 group both at 1 and 3 months after onset of @entity583 compared to the non- @entity3918 group. End-tidal @entity544 pressure was lower and the rate of increase of minute ventilation to @entity544 output was higher in the @entity3918 group. Plasma brain natriuretic peptide was higher in the @entity3918 group. delta HR/log delta NE was 19.4 +/- 4.0 in the @entity3918 group and 22.2 +/- 5.6 in the non- @entity3918 group (p < 0.01), and increased in only the non- @entity3918 group. delta HR/log delta NE was more closely correlated with peak @entity26 uptake in the @entity3918 group than in the non- @entity3918 group. CONCLUSIONS: Impaired response to exercise training may be caused, in part, by impaired heart rate reserve to exercise in @entity1 with @entity6 .

[Different effects of exercise training in @entity1 with XXXX with or without @entity6 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3918 :: ('MESH:D009223', 'Disease') :: ['DM'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity544 :: ('MESH:D002245', 'Chemical') :: ['carbon dioxide'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity1063 :: ('MESH:D009638', 'Chemical') :: ['norepinephrine']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
