We retrospectively reviewed 27 cases diagnosed as idiopathic @entity7995 between 1992 and 2001 at Kaohsiung Veterans General Hospital to assess the clinical features, visual prognosis, neuroimaging, laboratory studies, and development of @entity15 in Chinese @entity1 with @entity7995 . @entity1 age ranged from 13 to 54 years (mean, 35.8 +/- 11.3 years). Five cases presented as bilateral @entity7995 and 22 as unilateral. Visual function improved gradually from 2 weeks after treatment. Twelve (44.4%) cases showed disc swelling and @entity3856 was also noted in 44.4% of @entity1 . All cases that underwent visual field and visual evoked potential tests showed @entity66 . Of the 23 cases that underwent neuroimaging studies, including computerized tomography (17 @entity1 ) and magnetic resonance imaging (6 @entity1 ), 10 revealed optic nerve thickening. Four cases (14.8%) developed @entity15 during follow-up (mean, 4.3 years). The incidence of disc swelling was higher than that reported by the @entity7995 Treatment Trial, but the incidence of @entity3856 , the presence of periventricular plaques, and the development of @entity15 were lower in our study. The unilateral group had significantly better visual outcome than the bilateral group.

XXXX : clinical analysis of 27 cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['abnormality in lesion eyes'] @entity7995 :: ('MESH:D009902', 'Disease') :: ['optic neuritis', 'Optic Neuritis'] @entity3856 :: ('MESH:D058447', 'Disease') :: ['ocular pain', 'initial ocular pain'] @entity15 :: ('MESH:D009103', 'Disease') :: ['multiple sclerosis']
@entity7995 :: (MESH:D009902,Disease) :: ['Optic neuritis']
