The aim of the present study was to investigate the correlation between @entity2204 ( @entity2204 ) gene polymorphisms and the occurrence of @entity1791 and @entity2299 . A total of 180 Uyghur individuals, including 90 @entity1791 @entity1 and 90 healthy controls, were enrolled in this study. The blood lipid profiles of the @entity1 and controls were investigated and compared, and the composition of the urinary calculi was determined. The polymorphisms of the @entity2204 alleles were analyzed using polymerase chain reaction-restriction fragment length polymorphism analysis. Three common genotypes of the @entity2204 gene, @entity68442 , were detected in the @entity1791 @entity1 and control group. In the @entity1 group, 28 @entity1 with the E3/3 genotype (30.1%), 58 @entity1 with the E3/4 genotype (64.4%) and four @entity1 with the E4/4 genotype (4.5%) were identified. By contrast, in the control group, 52 @entity1 with the E3/3 genotype (57.8%), 35 @entity1 with the E3/4 genotype (38.9%) and three @entity1 with the E4/4 genotype (3.3%) were identified. The frequency of the E3/4 genotype was found to be significantly higher in the @entity1 group when compared with the control group (  (2)=12.96; P<0.001). In addition, the frequency of the E4 allele was significantly higher in the @entity1 group when compared with the control group (  (2)= 6.61; P=0.025). In conclusion, the occurrence of @entity1791 was found to be associated with @entity2204 gene polymorphisms, and the E4 allele may be a potential susceptibility factor for @entity1791 .

Correlation between @entity2204 gene polymorphisms and the occurrence of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity2204 :: ('348', 'Gene') :: ['apolipoprotein E', 'ApoE'] @entity1791 :: ('MESH:D052878', 'Disease') :: ['urolithiasis'] @entity68442 :: ('25915;9354', 'Gene') :: ['E3/3, E3/4 and E4/4']
@entity1791 :: (MESH:D052878,Disease) :: ['urolithiasis']
