PURPOSE: To assess the clinical utility of a new method for real-time estimation of T1 during the first pass of contrast agent by using this method to examine @entity1313 . MATERIALS AND METHODS: The multi-phase spoiled gradient-echo pulse sequence using the double-echo magnetic resonance (MR) technique was modified. In the first half of the pulse sequence, the flip angle was varied systematically. Then, static T1 values were calculated using differences in MR signal intensities between different flip angles. In the latter half of this sequence, changes in absolute T1 were calculated using differences in signal intensities before and after injection of contrast agent. The double-echo MR data were used to minimize the T2* effect. Five cases of @entity808 and seven cases of @entity1653 were examined. Changes in T1 during the first pass of contrast agent were compared between @entity808 and @entity1653 . RESULTS: Changes in absolute T1 were clearly demonstrated on the parametric map. Although the changes in absolute T1 during the first pass of contrast agent did not allow differentiation between the two types of @entity5 , the mean gradient after the first pass was statistically higher for @entity808 than for @entity1653 (P < 0.05; @entity1653 , 0.011 +/- 0.012 second(-1)/second; @entity808 , 0.034 +/- 0.020 second(-1)/second). CONCLUSION: The present method appears to be useful for estimation of dynamic T1 changes in @entity1313 in clinical settings.

Dynamic T1 estimation of XXXX using double-echo dynamic MR imaging.

@entity808 :: ('MESH:D009442', 'Disease') :: ['neurinoma'] @entity1653 :: ('MESH:D008579', 'Disease') :: ['meningioma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['brain tumors']
@entity1313 :: (MESH:D001932,Disease) :: ['brain tumors']
