BACKGROUND: @entity887 ( @entity887 ) for endovascular treatment of @entity438 was developed to reduce the risk of @entity439 recurrence and the rate of retreatment. The aim of this systematic review was to verify the efficacy of @entity887 , also in comparison to bare @entity902 coils (BPC). MATERIAL AND METHODS: A systematic literature search was performed by two independent reviewers for articles published until January 31st, 2013 on the follow-up recurrence rate of @entity438 with hydrogel-coated coils. RESULTS: Thirteen articles on the use of @entity887 for embolization of @entity438 were included in this study, for a total of 1683 embolized @entity439 . Significant heterogeneity was found regarding @entity1 populations, methods of @entity439 coiling, follow-up schedules, and recurrence definitions. The pooled rate of @entity439 was 55% (95%CI, 38-70%); 59% (95%CI, 43-74%) in the subgroup of @entity439 treated with the use of @entity887 . The pooled total recurrence rate was 19% (95%CI, 15-24%); 17% (95%CI, 14-22%) in the @entity887 -treated subgroup. The pooled major recurrence rate was 12% (95%CI, 8-18%); 11% (95%CI, 7-16%) in the @entity887 -treated subgroup. Comparing both types of coils, the pooled odds ratio for total recurrence was 0.63 (95%CI, 0.45-0.88; p=0.008) in favor of @entity887 . CONCLUSIONS: Embolization of @entity438 using @entity887 seems to result in a lower rate of recurrence than that obtained using BPC, which is in line with the only randomized controlled trial. High-quality prospective studies are needed to define specific indications for the use of hydrogel-coated coils.

Follow-up of XXXX with hydrogel embolic system: Systematic review and meta-analysis.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity887 :: ('MESH:D004617', 'Disease') :: ['HES', 'Hydrogel embolic system'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms', 'aneurysm', 'initial complete aneurysm occlusion'] @entity902 :: ('MESH:D010984', 'Chemical') :: ['platinum'] @entity438 :: ('MESH:D002532', 'Disease') :: ['cerebral aneurysms', 'intracranial aneurysm embolization']
@entity438 :: (MESH:D002532,Disease) :: ['cerebral aneurysm embolization']
