OBJECTIVE: The purpose of this study was to evaluate the frequency of maternal @entity455 and to determine the usefulness of placental examination in correlation with clinical manifestation of pregnancy-induced @entity101 . STUDY DESIGN: We investigated 350 pregnancy-induced @entity101 placentas over a 2.5-year period (January 2002-June 2004) to identify the potential usefulness of the maternal @entity455 in histologic diagnosis and corroboration of clinical @entity1468 . This study was carried out at West Virginia University Ruby Memorial Hospital, where 1271 placentas were examined macroscopically and microscopically for the period. The presence or absence of vascular changes, @entity1188 , @entity715 , @entity5869 , and @entity5870 were investigated for each placenta with the clinical diagnosis of @entity1468 or pregnancy-induced @entity101 . RESULTS: Two types of vascular changes that are characteristic of pregnancy-induced @entity101 , namely maternal atherosis and fibrinoid medial necrosis, were found in 21.4% of the placentas (75/350 placentas). These vascular changes were found mainly in the decidua capsularis of the membrane rolls, not on the decidua basalis of the maternal floor. There were more placental @entity1188 within these placentas (32.3%; 113/350 placentas). Intervillous @entity715 was 18.9% (66/350 placentas); microscopic abruption was 6.3% (22/350 placentas); chorangiosis was 10.9% (38/350 placentas), and @entity5870 was 8.6% (30/350 placentas). CONCLUSION: These findings demonstrate that the maternal vascular changes that are characteristic of pregnancy-induced @entity101 are found in approximately 1 of 5 pregnancy-induced @entity101 placentas. Examination of pregnancy-induced @entity101 placentas should be based on a combination of a number of histologic changes. Furthermore, the decidua capsularis of the fetal membrane roll, rather than the decidua basalis of the maternal floor, of the placenta should be examined for these maternal vascular changes.

Maternal XXXX and histologic diagnosis of @entity1468 : poor correlation of histologic changes and clinical manifestation.

@entity455 :: ('MESH:D014652', 'Disease') :: ['vasculopathy'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity5870 :: ('MESH:D002821', 'Disease') :: ['chorioamnionitis'] @entity5869 :: ('MESH:D000037', 'Disease') :: ['abruption, chorangiosis'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarctions'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['preeclampsia'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity455 :: (MESH:D014652,Disease) :: ['vasculopathy']
