UNASSIGNED: Although @entity25 is common in @entity1030 ( @entity1030 ), relatively little is known on the effect of the exacerbation on sleep quality. Accordingly, we longitudinally assessed sleep variables during exacerbations and clinical stability. This is a sub-study of a larger observational analysis. Inclusion criteria were clinically stable @entity1030 and two or more clinical exacerbations in the preceding 12 months. @entity1 were followed for approximately 6 months and during this time the following were recorded daily: (1) @entity1030 exacerbations, which were determined in two ways, clinically and symptom defined using the exacerbations of chronic @entity358 tool (EXACT); (2) @entity25 , which was measured using the Stanford Sleepiness Scale; (3) subjective awakenings, which was measured from a sleep diary; and (4) sleep duration, efficiency, and objective awakenings, which was measured from actigraphy. These variables for exacerbation and non-exacerbation days were compared. Seventeen @entity1 (9 male, age 63    12 years, forced expiratory volume in 1 second 52    20%) entered data over 135    18 days. During this time, 15 @entity1 had 27 symptom-defined exacerbations and 8 had 9 clinically reported exacerbations. Symptom-defined exacerbation days were 26% of the total study days. More @entity25 , @entity25 ( @entity25 ), and decreased @entity25 ( @entity25 ) were present during exacerbations compared with clinical stability (p < 0.001). These disturbances tended to be greater during clinically reported exacerbations than during unreported events (p < 0.05). Increased @entity25 , less @entity25 , and poorer @entity25 are present during @entity1030 exacerbations.

A longitudinal assessment of sleep variables during exacerbations of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary disease'] @entity25 :: ('MESH:D012893', 'Disease') :: ['decreased total sleep time', 'TST', 'daytime sleepiness', 'sleep efficiency', 'SE', 'sleep disturbance'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease', 'COPD']
@entity1030 :: (MESH:D029424,Disease) :: ['chronic obstructive pulmonary disease']
