BACKGROUND: Arthroplasty @entity1 with complications may be sensitized to implant components. OBJECTIVES: To quantify patch test reactions to implant materials in @entity27760 @entity1 with complications, and to evaluate the benefit of late patch test reading at D6. METHODS: Analyses of patch test reactions to baseline series and bone cement components and of the questionnaire-aided histories of 250 consecutive @entity1 with suspected implant @entity566 were performed. Patch tests were read at D2, D3, and D6. RESULTS: There were 187 positive reactions to the 29 allergens of the baseline series, and 52 to the seven allergens of the bone cement series. Forty-nine of 250 @entity1 reacted to the bone cement series. In contrast to 'early allergens' such as fragrance mix, late reading at D6 increased the number of positive reactions by 11/32 for @entity3406 , 1/5 for @entity1953 , and 2/4 for @entity3407 . With bone cement components, most reactions were to @entity801 (25 of 250 @entity1 ), and 17 of 25 appeared only at D6. CONCLUSION: Late reading is useful for patch tests with metals and bone cement components. With only D2/D3 readings, 32 reactions to @entity3406 , @entity1953 , @entity3407 and bone cement components would have been missed. This underlines the utility of late reading in general and in complicated cemented arthroplasty @entity1 , given the unexpectedly high number of @entity801 reactions.

High frequency of contact @entity566 to implant and bone cement components, in particular XXXX , in cemented arthroplasty with complications: usefulness of late patch test reading.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3406 :: ('MESH:D009532', 'Chemical') :: ['nickel'] @entity801 :: ('MESH:D005839', 'Chemical') :: ['gentamicin'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergy'] @entity27760 :: ('MESH:C563017', 'Disease') :: ['aseptic cemented arthroplasty'] @entity3407 :: ('MESH:D002857', 'Chemical') :: ['chromium'] @entity1953 :: ('MESH:D003035', 'Chemical') :: ['cobalt']
@entity801 :: (MESH:D005839,Chemical) :: ['gentamicin']
