OBJECTIVE: To investigate the value of coronary pressure derived fractional flow reserve (FFR) measurements in supporting decisions about medical or surgical treatment in @entity1 with angiographically equivocal left main @entity3979 . DESIGN: A two centre prospective single cohort follow up study. INTERVENTIONS: FFR of the left main coronary artery was determined in 54 consecutive @entity1 with angiographically equivocal @entity453 . If FFR was >/= 0.75, medical treatment was chosen; if FFR was < 0.75, surgical treatment was chosen. MAIN OUTCOME MEASURES: Freedom from death, @entity583 , or any coronary revascularisation procedure. RESULTS: In 24 @entity1 (44%), FFR was >/= 0.75 and medical treatment was chosen (medical group). In the remaining 30 @entity1 (56%), FFR was < 0.75 and bypass surgery was performed (surgical group). Mean (SD) follow up was 29 (15) months (range 12-65 months). Survival among @entity1 at three years of follow up was 100% in the medical group and 97% in the surgical group. Event-free survival was 76% in the medical group and 83% in the surgical group. CONCLUSIONS: FFR supports decision making in equivocal @entity453 . If FFR is below 0.75, the decision for bypass surgery is supported. If FFR is above 0.75, a conservative approach is justified.

Value of fractional flow reserve in making decisions about bypass surgery for equivocal XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity453 :: ('MESH:D003324', 'Disease') :: ['left main coronary artery disease'] @entity3979 :: ('MESH:D023921', 'Disease') :: ['coronary artery stenosis'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction']
@entity453 :: (MESH:D003324,Disease) :: ['left main coronary artery disease']
