PURPOSE: To present a propensity score matching analysis comparing the 1-year outcomes of de novo femoropopliteal lesions treated with drug-eluting stents (DES) or bare @entity5648 stents (BNS). METHODS: A retrospective review was conducted of 452 limbs in 389 @entity1 (mean age 74  8 years; 284 @entity1 ) treated with DES implantation and 1808 limbs in 1441 @entity1 (mean age 72  9 years; 1023 @entity1 ) implanted with BNS for de novo femoropopliteal lesions. One-year follow-up data were available on all @entity1 . The primary endpoint was 12-month @entity256 assessed by duplex ultrasonography or follow-up angiography within   2 months. Secondary endpoint was major adverse limb events (MALE) including major amputation, any reintervention, and @entity256 . RESULTS: The BNS group was more likely to have current smoking, chronic total occlusion, and poor below-the-knee runoff. The stratification analysis demonstrated that @entity6 ( @entity6 ) and reference vessel diameter (RVD) had a significant interaction on the association of DES vs BNS implantation with @entity256 (interaction p<0.05). Thus, the population was stratified into 4 subgroups (1: - @entity6 , RVD >= 5 mm, 2: + @entity6 , RVD >= 5 mm, 3: - @entity6 , RVD <5 mm, and 4: + @entity6 , RVD <5 mm); the RVD threshold was empirically determined. There were no significant intergroup differences in baseline variables after matching. There was no significant difference in @entity256 risk between DES and BNS in the RVD >= 5 mm subgroup regardless of the presence of @entity6 . The DES group had a significantly higher @entity256 risk in the RVD <5 mm subgroup regardless of the presence of @entity6 . No significant difference was observed in the risk of major amputation, reintervention, or MALE in any subgroup. CONCLUSION: These results suggest that a first-generation DES was not superior to a conventional BNS for femoropopliteal lesions.

Propensity Score Analysis Comparing Clinical Outcomes of Drug-Eluting vs Bare XXXX Stents in Femoropopliteal Lesions.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity6 :: ('MESH:D003920', 'Disease') :: ['DM', 'diabetes mellitus'] @entity256 :: ('MESH:D023903', 'Disease') :: ['restenosis'] @entity5648 :: ('MESH:C013616', 'Chemical') :: ['nitinol']
@entity5648 :: (MESH:C013616,Chemical) :: ['Nitinol']
