BACKGROUND: The relation between left ventricular (LV) remodeling and @entity943 after @entity583 is poorly documented. We investigated the relations between LV size, @entity1184 , and function and @entity943 in 263 @entity1 from the Survival and Ventricular Enlargement (SAVE) study, using quantitative 2D echocardiography and ambulatory ECG monitoring after @entity583 . METHODS AND RESULTS: Transthoracic 2D echocardiograms and @entity943 monitoring were performed at baseline (mean, 11 days) and 1 and 2 years after @entity1188 . LV size, short-axis muscle (mass) area (LVMA), and function were quantified from 2D echocardiograms. The prevalence of @entity1165 ( @entity1165 ) and frequent @entity1540 ( @entity1540 [ @entity1540 ] >10/h) was assessed from ambulatory ECG. @entity1165 and @entity1540 >10/h occurred in 20% and 29% of @entity1 at baseline, in 22% and 35% at 1 year and 23% and 39% at 2 years, respectively. @entity1165 and @entity1540 >10/h at baseline and 1 and 2 years were significantly related to LV size, LVMA, and function. Furthermore, changes in LV size and function from baseline to 2 years predicted both @entity1165 and @entity1540 >10/h. The study was underpowered to detect treatment effect of ACE inhibitors and beta-adrenergic receptor blockers but did not alter the relations between @entity943 , LV size, and function. CONCLUSIONS: Quantitative echocardiographic assessment of LV size, LVMA, and function and changes in these measurements over time predict @entity943 after @entity1188 . Altered LV architecture and function during postinfarction LV remodeling provide an important substrate for triggering high-grade @entity943 .

Left ventricular remodeling and @entity943 after XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['VT', 'ventricular tachycardia'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['hypertrophy'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarction'] @entity1540 :: ('MESH:D018879', 'Disease') :: ['ventricular ectopy', 'premature ventricular contractions', 'PVCs'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmias', 'arrhythmia']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
