UNASSIGNED: Purpose To assess predictors of reverse remodeling by using cardiac magnetic resonance (MR) imaging soon after @entity583 ( @entity583 ). Materials and Methods Written informed consent was obtained from all @entity1 , and the study protocol was approved by the institutional committee on @entity1 research, ensuring that it conformed to the ethical guidelines of the 1975 Declaration of Helsinki. Five hundred seven @entity1 (mean age, 58 years; age range, 24-89 years) with a first @entity583 were prospectively studied. @entity1188 size and @entity3885 ( @entity3885 ) were quantified at late @entity2287 -enhanced imaging. Reverse remodeling was defined as a decrease in left ventricular (LV) end-systolic volume index (LVESVI) of more than 10% from 1 week to 6 months after @entity583 . For statistical analysis, a simple (from a clinical perspective) multiple regression model preanalyzing @entity1188 size and @entity3885 were applied via univariate receiver operating characteristic techniques. Results @entity1 with reverse remodeling (n = 211, 42%) had a lesser extent (percentage of LV mass) of 1-week @entity1188 size (mean    standard deviation: 18%    13 vs 23%    14) and @entity3885 (median, 0% vs 0%; interquartile range, 0%-1% vs 0%-4%) than those without reverse remodeling (n = 296, 58%) (P < .001 in pairwise comparisons). The independent predictors of reverse remodeling were @entity1188 size (odds ratio, 0.98; 95% confidence interval [CI]: 0.97, 0.99; P = .04) and @entity3885 (odds ratio, 0.92; 95% CI: 0.86, 0.99; P = .03). Once @entity1188 size and @entity3885 were dichotomized by using univariate receiver operating characteristic techniques, the only independent predictor of reverse remodeling was the presence of simultaneous nonextensive @entity1188 ( @entity1188 size < 30% of LV mass and @entity3885 < 2.5% of LV mass) (odds ratio, 3.2; 95% CI: 1.8, 5.7; P < .001). Conclusion Assessment of @entity1188 size and @entity3885 with cardiac MR imaging soon after @entity583 enables one to make a decision in the prediction of reverse remodeling. (  ) RSNA, 2015 Online supplemental material is available for this article.

Prediction of Reverse Remodeling at Cardiac MR Imaging Soon after First ST-Segment-Elevation XXXX : Results of a Large Prospective Registry.

@entity1 :: ('9606', 'Species') :: ['Patients', 'human', 'patients'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['microvascular obstruction', 'MVO'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct-size MVO', 'Infarct', 'infarct'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST-segment-elevation myocardial infarction'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium']
@entity583 :: (MESH:D009203,Disease) :: ['Myocardial Infarction']
