OBJECTIVE: To investigate the follow-up results of the prophylactic laser treatment to macular soft drusen in age-related @entity1020 . METHODS: Prospective, 10 @entity1 with bilateral soft drusen and with good visual acuity were observed for 8 years. 10 eyes were treated. The fellow eyes were as control group. @entity941 angiography and Amsler test were studied after 8 years. Scanning laser ophthalmoscope was performed after 2 years. Some of them were performed multifocal ERG to test the macular function after 3 years. RESULTS: There is no @entity1940 in both the laser group and the control group. There is no differences in the best corrected visual acuity after 8 years. All eyes had good fovea fixation. Light sensitivity of both eyes had no significant difference to be found by scanning laser ophthalmoscope. The latencies and amplitude densities of the @entity3881 waves in the central first ring remained unchanged at 3 years post-treatment (before treatment t = -0.779, 0.722, -0.491, 0.286; after treatment t = 1.342, 0.043, 0.937, 0.350; P > 0.05) compared with the fellow eyes. CONCLUSIONS: There is no impairment to be found in the macula after preventive laser treatment. The treatment did not demonstrate a clinically significant benefit for @entity1940 in eyes of @entity1 with bilateral large drusen.

[Prophylactic laser treatment to macular soft drusen in age-related XXXX of updated results].

@entity1 :: ('9606', 'Species') :: ['persons', 'people'] @entity3881 :: ('1423', 'Gene') :: ['N1 and P1'] @entity1940 :: ('MESH:D020256', 'Disease') :: ['choroidal neovascularization'] @entity941 :: ('MESH:D019793', 'Chemical') :: ['Fluorescein'] @entity1020 :: ('MESH:D008268', 'Disease') :: ['macular degeneration']
@entity1020 :: (MESH:D008268,Disease) :: ['maculopathy']
