BACKGROUND: @entity10409 ( @entity10409 ) is a @entity8053 defined by an exaggerated increase in heart rate upon changing posture. It is associated with disturbances involving multiple organ systems, including neurologic, dermatologic, and @entity344 . Previous studies identified GI complaints in these @entity1 and showed @entity356 and electrical activity abnormalities. However, the full spectrum of @entity344 and their impact on quality of life remains unclear. METHODS: A 30-question survey of @entity344 was collected from 28 @entity1 with @entity10409 seen in the Boston Medical Center Autonomic Clinic. Answers were recorded on a Likert rating scale. Symptoms were positive if @entity1 answered "strongly agree" or "agree" and negative if they answered "strongly disagree" or "disagree." Responses were collected and analyzed. RESULTS: The most commonly reported @entity344 were @entity390 (86%), irregular bowel movements (71%), @entity490 (70%), and @entity1142 (70%). Additionally, 82% of @entity1 reported having @entity344 more than once per week, and 71% reported having seen a GI specialist, and symptoms did not improve with changes in position. Twelve @entity1 had undergone a @entity356 study, and six of these @entity1 reported receiving a diagnosis of @entity7623 or delayed @entity356 . CONCLUSIONS: @entity344 are common, frequent, and prolonged in @entity1 with @entity10409 , likely impacting quality of life. Given the importance of the enteric nervous system to normal GI functioning, the same autonomic impairment leading to @entity10409 may result in abnormal gut motility and ultimately subjective GI discomfort.

@entity344 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity10409 :: ('MESH:D054972', 'Disease') :: ['Postural tachycardia syndrome', 'POTS'] @entity344 :: ('MESH:D005767', 'Disease') :: ['GI symptoms', 'gastrointestinal (GI) symptoms', 'GI disturbances'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity7623 :: ('MESH:D018589', 'Disease') :: ['gastroparesis'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation'] @entity8053 :: ('MESH:D054969', 'Disease') :: ['dysautonomia'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric emptying']
@entity10409 :: (MESH:D054972,Disease) :: ['postural tachycardia syndrome']
