BACKGROUND AND AIMS: The literature on @entity14 ( @entity14 ) screening and ethnic diversity is dominated by studies from the USA. There are no such published data from the UK @entity5 screening programme (BCSP) population. The Wolverhampton Bowel Cancer Screening Centre serves a population of 900   000 in the Black Country and South Staffordshire. South Asians (SA) comprise 9% of the population. We aimed to determine the effects of ethnicity and sex on the risk for @entity5 or @entity652 detected by colonoscopy following a positive @entity1503 test over a 5-year period (2007-2011). METHODS: Data were collected from the prospectively maintained BCSP cohort. South Asian @entity1 were identified and compared with those of non-South Asian ethnicity, and colonoscopy outcomes were determined. RESULTS: A total of 3552 @entity1 underwent BCSP colonoscopy (non-South Asian=3363; SA=189). There were 271 @entity5 (7.6%) detected within the non-South Asian group and seven @entity5 (0.2%) in the South Asian population (P<0.05). The probability of @entity694 is higher [odds ratio (OR)=3.84, P<0.05] in non-South Asians compared with South Asians. @entity1 in the 65-70-year age group have the highest risk (OR=1.60; P<0.05) for @entity14 . During the study 1313 @entity652 were detected. A total of 771 high-risk and intermediate-risk @entity652 were detected in the non-South Asian group, and 14 were detected in the South Asian group. The risk of @entity652 in non-South Asians is six times higher than in South Asians (OR=5.99, P<0.001) following positive @entity1503 testing. CONCLUSION: There are fewer @entity14 in South Asians compared with the non-South Asian population in this regional study. This is the first such study in the BCSP population.

Ethnic variation in @entity14 risk following a positive @entity1503 test in an English XXXX screening programme centre.

@entity1 :: ('9606', 'Species') :: ['participants', 'Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['bowel cancer', 'cancers', 'cancer'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['faecal occult blood'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancers', 'CRC', 'colorectal cancer'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas', 'adenoma'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer']
@entity5 :: (MESH:D009369,Disease) :: ['bowel cancer']
