In @entity35 , axons of external urethral sphincter (EUS) motoneurons travel through the anastomotic branch of the @entity3815 (ABPD) and anastomotic branch of the lumbosacral trunk (ABLT) and converge in the motor branch of the sacral plexus ( @entity12221 ). The aim of the present study was to determine in female @entity35 the contribution of these somatomotor pathways and urethral sensory innervation from the dorsal nerve of the clitoris on urinary continence and voiding. EUS electromyographic (EMG) activity during cystometry, leak point pressure (LPP), and voiding efficiency (VE) were assessed in anesthetized virgin Sprague-Dawley female @entity35 before and after transection of the above nerve branches. Transection of the @entity12221 eliminated EUS EMG, decreased LPP by 50%, and significantly reduced @entity1494 duration, peak pressure, intercontraction interval, and VE. Transection of the ABPD or ABLT decreased EUS EMG discharge and LPP by 25% but did not affect VE. Transection of the dorsal nerve of the clitoris did not affect LPP but reduced contraction duration, peak pressure, intercontraction interval, and VE. We conclude that somatomotor control of micturition is provided by the @entity12221 with axons travelling through the ABPD and ABLT. Partial somatomotor urethral denervation induces mild @entity322 , whereas partial afferent denervation induces @entity409 . ABPD and ABLT pathways could represent a safeguard ensuring innervation to the EUS in case of @entity16 . Detailed knowledge of neuroanatomy and functional innervation of the urethra will enable more accurate animal models of neural development, disease, and dysfunction in the future.

Somatomotor and sensory urethral control of micturition in female XXXX .

@entity322 :: ('MESH:D014549', 'Disease') :: ['urinary incontinence'] @entity1494 :: ('MESH:D001745', 'Disease') :: ['bladder contraction'] @entity16 :: ('MESH:D009422', 'Disease') :: ['upper nerve damage'] @entity409 :: ('MESH:D008107', 'Disease') :: ['voiding dysfunction'] @entity3815 :: ('MESH:D060545', 'Disease') :: ['pudendal nerve'] @entity12221 :: ('116670(Tax:10116)', 'Gene') :: ['MBSP'] @entity35 :: ('10116', 'Species') :: ['rats']
@entity35 :: (10116,Species) :: ['rats']
