OBJECTIVES: In light of current FDA guidelines on opioid use in @entity1 , we sought to determine the risk of post-tonsillectomy @entity548 (PTH) in @entity1 who received @entity5018 with @entity1443 versus those who received narcotic with @entity1443 for @entity282 control. METHODS: This was an IRB-approved retrospective chart review of @entity1 at a tertiary-care pediatric center. The medical records of 449 @entity1 who received @entity1443 and @entity5018 following intracapsular tonsillectomy with or without adenoidectomy were reviewed (NSAID group) and compared with medical records of 1731 @entity1 who underwent intracapsular tonsillectomy and received @entity1443 with @entity10425 or @entity1287 with @entity1443 postoperatively (narcotic group). Main outcome measure was the incidence of PTH requiring return to the operating room. Secondary outcome measures included incidence of primary PTH, secondary PTH, and postoperative evaluation in the emergency department or readmission for @entity158 . RESULTS: Incidence of PTH requiring return to the operating room was higher in the NSAID group (1.6%) compared with the narcotic group (0.5%), P=0.01. Incidence of primary PTH was significantly higher in the NSAID group (2%) versus the narcotic group (0.12%), P<0.0001. Incidence of secondary PTH was 3.8% in the NSAID group and 1.1% in the narcotic group (P<0.0001). CONCLUSION: Use of @entity5018 after intracapsular tonsillectomy in @entity1 is associated with statistically significant increase in PTH requiring return to the operating room, as well as an increase in overall rates of both primary and secondary PTH. @entity5018 provides pain control that is at least equivalent to narcotic and is not associated with @entity1576 . Further study of @entity5018 use in the post-tonsillectomy @entity1 is warranted.

Postoperative nonsteroidal anti-inflammatory drugs and risk of XXXX in pediatric intracapsular tonsillectomy.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity5018 :: ('MESH:D007052', 'Chemical') :: ['Ibuprofen', 'ibuprofen'] @entity1287 :: ('MESH:D006853', 'Chemical') :: ['hydrocodone'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory depression'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain and/or dehydration'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['acetaminophen'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity10425 :: ('MESH:D003061', 'Chemical') :: ['codeine']
@entity548 :: (MESH:D006470,Disease) :: ['bleeding']
