The aim of this study was to evaluate the possible favorable effect of @entity14295 - @entity5203 combination on salivary glands (SG) function in @entity1 with @entity2023 ( @entity2023 ) using SG scintigraphy. The study population consisted of 64 @entity1 with @entity2023 and 28 healthy controls: 14 males and 14 females, with mean age 32.3  8.6 years. The @entity1 were divided into two groups: the untreated @entity1 group of 32 @entity1 , 16 males and 16 females, mean age 28.5  5.4 years and the treated group, who received the standard clinically recommended oral dose of @entity5203 10mg/d and @entity14295 5mg/d for 6 weeks. This group consisted of 32 @entity1 , 16 males and 16 females, mean age 38.3  8.4 years. All @entity1 and healthy controls underwent SG scintigraphy. After the intravenous injection of technetium-99m pertechnetate, ((99m)Tc-P), dynamic SG scintigraphy was performed for 25min. Using the time-activity curves, the following glandular function parameters were calculated for the parotid and the submandibular SG: uptake ratio, maximum accumulation and ejection fraction. Results showed @entity1887 . All functional parameters obtained for the untreated @entity1 and for the @entity14295 - @entity5203 treated @entity1 were significantly lower than those in healthy controls (P<0.05). There was no statistically significant difference between treated and untreated @entity1 (P>0.05). In conclusion, our study showed that hypofunction of SG was present in all @entity1 with @entity2023 . This hypofunction, as tested by semi-quantitative SG scintigraphy, and also the quality of life did not improve after treatment with @entity5203 and @entity14295 .

The effect of antiallergic treatment with XXXX - @entity5203 on salivary glands function in @entity2023 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2023 :: ('MESH:D006255', 'Disease') :: ['AR', 'allergic rhinitis'] @entity1887 :: ('MESH:D000309', 'Disease') :: ['SG hypofunction'] @entity5203 :: ('MESH:C093875', 'Chemical') :: ['montelukast'] @entity14295 :: ('MESH:C121345', 'Chemical') :: ['desloratadine']
@entity14295 :: (MESH:C121345,Chemical) :: ['desloratadine']
