PURPOSE: To evaluate the long-term efficacy and safety of deep sclerectomy (DS) augmented with @entity1138 ( @entity1139 ) and injectable cross-linked hyaluronic acid implant (Healaflow) in medically refractory @entity726 @entity1 . MATERIALS AND METHODS: Our study included 96 eyes of 83 consecutive @entity1 with @entity1538 undergoing @entity1139 -DS with injectable cross-linked hyaluronic acid implant. Mean follow-up was 28.6  20.0 months. Variables analyzed were: intraocular pressure (IOP), best-corrected visual acuity, mean number of antiglaucomatous drugs, execution of postoperative maneuvres (goniopuncture, @entity4530 needling, and laser lysis of scleral flap sutures). Tonometric success was defined by 2 different thresholds, specifically IOP <=21 mm Hg (criterion A) and  <=15 mm Hg (criterion B). The procedure was defined as a qualified success if reached with medication and as a complete success if reached without. RESULTS: For criterion A, qualified and complete success rates were 96% and 94%, respectively, at 12 months, 95% and 92% at 24 months, and 92% and 89% at 36 months. For criterion B, qualified and complete success rates were 75% and 75%, respectively, at 12 months, 62% and 60% at 24 months, and 59% and 58% at 36 months. Goniopuncture was performed in 56 eyes (58%), @entity4530 needling with @entity1487 injection in 4 eyes (5.1%), and laser release of scleral flap sutures in 4 eyes (4%). Six eyes required additional filtering surgery. CONCLUSION: DS with Healaflow and @entity1139 seems to be an effective and safe technique to lower IOP in @entity1 affected by @entity1538 , with few @entity260 .

Deep Sclerectomy With XXXX and Injectable Cross-linked Hyaluronic Acid Implant: Long-term Results.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open-angle glaucoma'] @entity4530 :: ('MESH:D001768', 'Disease') :: ['bleb'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin C'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity1139 :: ('CHEBI:27504', 'Chemical') :: ['MMC'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-fluorouracil']
@entity1138 :: (MESH:D016685,Chemical) :: ['Mitomycin C']
