BACKGROUND AND OBJECTIVES: Stem cell technology offers a new hope for many @entity102 @entity1 . The types of stem cells are different with many differences existing between each type. Mesenchymal stem cells (MSCs) represent one type of adult stem cells that can be easily isolated, then re-transplanted to the @entity1 . This offers potential for their future application in treating @entity74 without fear of rejection possibility. MSCs can be isolated from different sources e.g. bone marrow (BMSCs) and adipose tissue (ADSCs). In the present study we compared BMSCs and ADSCs isolated from @entity35 . METHODS AND RESULTS: For this comparison, immunophenotyping, the analysis of growth rates, proliferation by colony forming unit-fibroblast assay, population doubling time, and trilineage differentiation assays were performed for both BMSCs and ADSCs. The findings revealed that despite no difference in immunphenotypic character between BMSC and ADSC, a better proliferative capacity was observed for ADSCs which would advocate their better use in regenerative applications. On the other hand, BMSCs showed more potential for osteogenic and chondrogenic differentiation. CONCLUSIONS: Our study showed that, despite many similarities between both types of cells, there are differences existing which can offer assistance on choosing type of cell to be used in specific diseases. Although ADSCs seem more promising for regenerative application generally, BMSCs may represent a better choice for treating @entity79 .

Characterization of mesenchymal stem cells derived from XXXX bone marrow and adipose tissue: a comparative study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic disorders'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone disorders'] @entity74 :: ('MESH:D030342', 'Disease') :: ['many disorders'] @entity35 :: ('10116', 'Species') :: ['Sprague-Dawley rats']
@entity35 :: (10116,Species) :: ['rat']
