BACKGROUND: @entity697 represent @entity395 which can lead to life threatening complications. Immunosuppressed @entity1 are affected primarily. The expansion of transplantation medicine and the progress in therapy of malignant diseases of the lymphatic system are associated with an increase of opportunistic systemic @entity364 . Therefore the otorhinolaryngologist is confronted increasingly with these problems and questions for surgery, especially if the symptom of a periorbital @entity32 occurs as a sign for a beginning orbital complication and radiological signs of involvement of the paranasal sinuses exist. @entity1 : We report exemplary about two immunosuppressed @entity1 with an invasive and fulminant @entity364 of the paranasal sinuses. In spite of systemic antifungal therapy and surgical intervention, @entity75 caused a lethal course. CONCLUSIONS: In immunosuppressed @entity1 with clinical and radiological signs for a @entity1244 and a periorbital @entity32 an invasive @entity364 should be considered. Pathogenic aspergillus species are the most common identified in @entity364 . The disease with often lethal outcome requires a careful and fast diagnostic and therapy as well as interdisciplinary co-operation. If and when limited or extensive surgery should be performed remains, because of the rarity and the lacking experience with this disease, still a controversially discussed issue and depends on several factors: the kind of disease, the immunity, the @entity364 and the degree of tissue invasion.

[Acute and fulminant fungal sinusitis in immunosuppressed XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity1244 :: ('MESH:D012852', 'Disease') :: ['sinusitis'] @entity697 :: ('MESH:D000208', 'Disease') :: ['Acute and invasive fungal sinusitis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['intracranial and systemic complications'] @entity364 :: ('MESH:D009181', 'Disease') :: ['mycoses', 'fungal aspergillosis', 'subtype of invasive fungal sinusitis', 'fungal sinusitis'] @entity395 :: ('MESH:D035583', 'Disease') :: ['rare diseases']
@entity1 :: (9606,Species) :: ['patients']
