UNASSIGNED: @entity3814 ( @entity3814 ) occurs after stereotactic body radiation therapy (SBRT) for spine @entity3 . Recently, single fraction radiosurgery (sfSRS) is used more frequently. The aim of this study is to determine the clinical outcome of @entity3814 after sfSRS. Spinal instability neoplastic score (SINS) criteria were used to retrospectively score 143 consecutive vertebral segments in 79 @entity1 treated with @entity6815 . Follow-up MRI, @entity158 , and neurologic assessments obtained every 3-6  months. @entity158 also scored at 7, 14, and 30  days after sfSRS. Follow up was 16      18  months   SD, range 3-78. Long-term radiographic control occurred in 94  % of cases. @entity158 improvement resulted within 7  days in 100  % of cases with severe @entity158 and sustained long-term in 95  %. @entity3814 occurred in 21  % of segments: 30  % were de novo @entity3814 . The overall 1  year @entity174 free probability (1yFFP) was 76  %. Pre-existing @entity3814 resulted in higher probability to progress: 1yFFP 90 versus 60  %. Symptoms presented in 6  % of cases with de novo @entity3814 and 39  % with progressive. The former were treated with vertebral augmentation (VA), the latter with open surgery. Surgery/VA prior to @entity6815 did not change risk of progressive @entity3814 . Univariate but not multivariate analysis identified histology (colorectal), pre-existing @entity3814 , and @entity158 (severe) as significant predictors of @entity3814 . In conclusion, sfSRS compares favourably to SBRT for radiographic and @entity158 control with similar @entity3814 risk. @entity1 with pre-existing @entity3814 have a higher probability to progress, become symptomatic, and require surgery. These results may help discussing risk and benefits with @entity1 undergoing sfSRS for spinal @entity3 and developing new treatment algorithms.

Clinical outcome of vertebral compression XXXX after single fraction spine radiosurgery for spinal metastases.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity3814 :: ('MESH:D050815', 'Disease') :: ['Vertebral compression fracture', 'VCF'] @entity6815 :: ('MESH:D056730', 'Disease') :: ['SRS'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity174 :: (MESH:D050723,Disease) :: ['fracture']
