This paper reports the results of the " @entity11168 " (" @entity6 REinforcement of Adequate Management") study performed among 42 general practitioners. A treatment algorithm was proposed to intensify the management of type 2 @entity6 @entity1 in case of poor control (HbA1C > 7.5% and fasting blood @entity413 > 140 mg/dl) before asking for an advice from a diabetologist. A total of 163 @entity1 participated in the study: 84 @entity1 and 79 @entity1 , 59 +/- 10 years old; 5.2 +/- 6.1 years of known duration of @entity6 ; BMI: 30.7 +/- 5.8 kg/m2. Almost two thirds of @entity1 received an antihypertensive agent, one third a lipid-lowering drug, and three quarters at least one antidiabetic agent: 22% a @entity5736 , 18% @entity2449 , 25% a combined oral therapy, 10% insulin (alone or in combination). At baseline, mean @entity4051 C averaged 7.1 +/- 2.2% (N: 4-6%), and 34% of @entity1 had HbA1C > 7.5%. From these 163 @entity1 , 100 were evaluated after 12 months, 57% being well controlled vs 36% at baseline. Among the 32 @entity1 whose hypoglycaemic treatment was intensified, @entity4051 C level significantly decreased by almost 0.8% (p < 0.05). Despite precise guidelines, 55% of @entity1 with HbA1C > 7.5% had no treatment adjustment, essentially in the group already on oral bitherapy or on insulin. Among the 65 @entity1 evaluated after 24 months, the percentage of well controlled @entity1 decreased to 44% (vs 51% after 12 months). The decision of switching to insulin was often delayed (no @entity1 after 1 year and 2 @entity1 only after 2 years). In conclusion, the " @entity11168 " study demonstrates the feasibility, but also the difficulty, of optimising the management of type 2 @entity6 @entity1 in general practice.

[Optimizing the management of type 2 diabetics: results of the " XXXX " study in general practice].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity4051 :: ('3039', 'Gene') :: ['HbA1'] @entity11168 :: ('30818', 'Gene') :: ['DREAM'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetic', 'diabetes'] @entity5736 :: ('D013453', 'Chemical') :: ['sulfonylurea'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity2449 :: ('MESH:D008687', 'Chemical') :: ['metformin']
@entity11168 :: (30818,Gene) :: ['DREAM']
