OBJECTIVE: Many @entity1 with @entity449 ( @entity2334 ). Because open repair is associated with a high morbidity and mortality, hybrid approaches to @entity2334 repair are emerging. In this study, we evaluated the midterm outcomes and aortic remodeling of a hybrid technique that combines proximal @entity439 repair (TEVAR), followed by staged distal open thoracoabdominal repair for @entity1 with Crawford extent I or II TAAAs secondary to chronic @entity1580 . METHODS: We identified 19 @entity1 with Crawford extent I (n  = 1) or extent II (n  = 18) TAAAs secondary to chronic @entity1580 who underwent a staged hybrid repair from 2007 to 2014 at our institution. Nine @entity1 had previous open ascending aortic surgery for type I @entity1580 . Stage 1 TEVAR was performed via percutaneous (n  = 8), femoral cutdown (n  = 8), or iliac exposure (n  = 3). The left subclavian artery was covered in nine @entity1 and revascularized in eight @entity1 using carotid-subclavian bypass (n  = 7) or laser fenestration (n  = 1). Stage 2 open repair was performed a median of 18  weeks later with partial cardiopulmonary bypass via left femoral arterial and venous cannulation for visceral and lower body perfusion. The open thoracoabdominal graft was anastomosed proximally in an end to end fashion with the endograft. We then assessed surgical morbidity and mortality, midterm survival, and freedom from reintervention. Aortic remodeling was measured and change in maximum aortic and false lumen diameter at last follow-up (median, 3  years) from baseline was assessed. RESULTS: There were no deaths, @entity64 , or @entity177 in this cohort. After stage 1 TEVAR, three @entity1 required repeat intervention for endoleak (type IA, n  = 1; type IB, n  = 1; type II, n  = 1) before open repair. After stage 2 open repair, there was a single delayed permanent @entity912 2  weeks after discharge. At a median 3-year follow-up (range, 6 months-6.2  years), there were no deaths, neurologic events, @entity1070 , or @entity2334 reinterventions. Complete false lumen @entity715 occurred in 100% of the @entity1 , with maximum false lumen diameter decreasing from 34.3     15.3  mm to 13.2     12.0  mm  (P  < .01) and total aortic diameter decreasing from 60.2     9.0  mm to 49.4     9.6  mm  (P  <  .01). CONCLUSIONS: Staged hybrid @entity2334 repair, using a combination of proximal TEVAR with open distal repair, can be performed using established endovascular skills and technology coupled with traditional open aortic surgical techniques, with low surgical morbidity and mortality. In the midterm, staged hybrid @entity2334 repair was associated favorable survival, aortic remodeling, and freedom from reintervention.

Staged hybrid repair of extensive XXXX secondary to chronic @entity1580 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['strokes'] @entity449 :: ('MESH:D001014', 'Disease') :: ['aortic dissection develop Crawford extent I or II thoracoabdominal aortic aneurysms'] @entity912 :: ('MESH:D010243', 'Disease') :: ['paralysis'] @entity1070 :: ('MESH:D057867', 'Disease') :: ['endoleaks'] @entity177 :: ('MESH:D051437', 'Disease') :: ['chronic renal failure'] @entity2334 :: ('MESH:D017545', 'Disease') :: ['TAAA'] @entity439 :: ('MESH:D000783', 'Disease') :: ['thoracic endovascular aneurysm'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity1580 :: ('MESH:C562834', 'Disease') :: ['aortic dissection']
@entity2334 :: (MESH:D017545,Disease) :: ['thoracoabdominal aortic aneurysms']
