BACKGROUND: Can the application of local anesthetics (Neural Therapy, NT) alone durably improve @entity158 symptoms in referred @entity1 with chronic and refractory @entity158 ? If the application of local anesthetics does lead to an improvement that far exceeds the duration of action of local anesthetics, we will postulate that a vicious circle of @entity158 in the reflex arcs has been disrupted (hypothesis). METHODS: Case series design. We exclusively used @entity8162 or @entity3303 . The inclusion criteria were severe @entity158 and chronic duration of more than three months, @entity158 unresponsive to conventional medical measures, written referral from physicians or doctors of chiropractic explicitly to NT. @entity1 with improvement of @entity158 who started on additional therapy during the study period for a reason other than @entity158 were excluded in order to avoid a potential bias. Treatment success was measured after one year follow-up using the outcome measures of @entity158 and analgesics intake. RESULTS: 280 @entity1118 @entity1 were included; the most common reason for referral was @entity615 . The average number of consultations per @entity1 was 9.2 in the first year (median 8.0). After one year, in 60 @entity1 @entity158 was unchanged, 52 @entity1 reported a slight improvement, 126 were considerably better, and 41 @entity158 -free. At the same time, 74.1  % of the @entity1 who took analgesics before starting NT needed less or no more analgesics at all. No adverse effects or complications were observed. CONCLUSIONS: The good long-term results of the targeted therapeutic local anesthesia (NT) in the most problematic group of @entity1118 @entity1 (unresponsive to all evidence based conventional treatment options) indicate that a vicious circle has been broken. The specific contribution of the intervention to these results cannot be determined. The low costs of local anesthetics, the small number of consultations needed, the reduced intake of analgesics, and the lack of adverse effects also suggest the practicality and cost-effectiveness of this kind of treatment. Controlled trials to evaluate the true effect of NT are needed.

Long-term results of therapeutic local anesthesia (neural therapy) in 280 referred refractory @entity1118 XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity8162 :: ('MESH:D011343', 'Chemical') :: ['procaine'] @entity615 :: ('MESH:D001416', 'Disease') :: ['back pain'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1118 :: ('MESH:D059350', 'Disease') :: ['chronic pain']
@entity1 :: (9606,Species) :: ['patients']
