UNASSIGNED: Plant @entity15586 and its metazoan ortholog @entity53150 are @entity563 / @entity369 -rich (SR)-like RNA binding proteins that function in splicing/postsplicing events and regulate diverse processes in eukaryotes. Interactions of @entity15586 with both RNAs and proteins are crucial for regulating RNA processing. However, in vivo RNA targets of @entity15586 are currently unclear. Using RNA immunoprecipitation followed by high-throughput sequencing, we identified over 4000 @entity958 RNAs that directly or indirectly associate with @entity15586 , designated as @entity15586 -associated RNAs ( @entity6723 ). Comprehensive analyses of these @entity6723 revealed several roles for @entity15586 . First, @entity15586 associates with and regulates the expression of 30% of @entity2271 ( @entity2272 ) signaling genes at the postsplicing level. Second, although most @entity6723 are derived from intron-containing genes, surprisingly, 340 @entity6723 are derived from intronless genes. Expression analysis of the @entity6723 suggests that @entity15586 differentially regulates intronless and intron-containing @entity6723 . Finally, we identified four overrepresented RNA motifs in @entity6723 that likely mediate @entity15586 's recognition of its targets. Therefore, @entity15586 plays an unexpected role in mRNA processing of intronless genes, and numerous @entity2272 signaling genes are targeted for regulation at the posttranscriptional level. The diverse molecular functions of @entity15586 uncovered in this study are likely applicable to other species in view of its conservation across eukaryotes.

Transcriptome-Wide Identification of RNA Targets of XXXX SERINE/ARGININE-RICH45 Uncovers the Unexpected Roles of This RNA Binding Protein in RNA Processing.

@entity2272 :: ('CHEBI:2365', 'Chemical') :: ['ABA'] @entity2271 :: ('MESH:D000040', 'Chemical') :: ['abscisic acid'] @entity6723 :: ('227859', 'Species') :: ['SARs'] @entity958 :: ('3702', 'Species') :: ['Arabidopsis thaliana'] @entity15586 :: ('838230(Tax:3702)', 'Gene') :: ['SR45'] @entity563 :: ('CHEBI:17822', 'Chemical') :: ['serine'] @entity53150 :: ('10921', 'Gene') :: ['RNPS1'] @entity369 :: ('CHEBI:29016', 'Chemical') :: ['arginine']
@entity958 :: (3702,Species) :: ['Arabidopsis']
