OBJECTIVE: Pregnancy-induced @entity604 may be further exacerbated by @entity3457 ( @entity3457 ). The authors compared the bone status of @entity3457 hospitalized (>= 7 days) pregnant @entity1 in the third trimester to ambulatory (AM) @entity1 at the same gestational age, using a prospective cross-sectional design. METHOD: @entity3457 was quantified in @entity3457 @entity1 by daily step counts using a pedometer for 7 consecutive days. Bone status was evaluated in the left and right calcaneus bones of both @entity3457 (n = 13) and AM (n = 20) @entity1 using quantitative ultrasound (QUS). RESULTS: @entity3457 @entity1 took an average of 1,504    1,377 steps/day. Speed of sound scores (1,543.05    41.97 m/s vs. 1,569.60    46.12 m/s) and broadband ultrasound attenuation (BUA) scores (107.93    9.59 dB/MHz vs. 114.69    17.06 dB/MHz) were not different between the @entity3457 and AM groups, respectively (p > .05). However, bone stiffness index (SI) scores (84.0    16.2 vs. 95.8    22.1, respectively, p < .05) were different between groups, indicating a greater relative risk of future @entity174 in the @entity3457 @entity1 . CONCLUSION: Increased @entity174 risk appears to be a negative side effect incurred through an average of 16 days of hospitalized @entity3457 in late pregnancy. Further investigations using a larger sample size are necessary to evaluate the effect of antepartum @entity3457 on bone status in the postpartum period to determine if bone status is further attenuated by breastfeeding or if recovery occurs with resumption of ambulation and return of menses and to assess future risk in these @entity1 as they age. Prenatal care providers should be made aware of these risks.

Bone status in activity-restricted pregnant XXXX assessed using calcaneal quantitative ultrasound.

@entity1 :: ('9606', 'Species') :: ['women'] @entity604 :: ('MESH:D016301', 'Disease') :: ['bone loss'] @entity3457 :: ('OMIM:612348', 'Disease') :: ['AR', 'activity restriction'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture']
@entity1 :: (9606,Species) :: ['women']
