PURPOSE: In conformal radiotherapy of @entity2 , penumbra broadening in lung tissue necessitates the use of larger field sizes to achieve the same target coverage as in a homogeneous environment. In an idealized model configuration, some fundamental aspects of field size reduction were investigated, both for the static situation and for a moving @entity5 , while maintaining the dose homogeneity in the target volume by employing a simple beam-intensity modulation technique. METHODS AND MATERIALS: An inhomogeneous phantom, consisting of @entity852 , cork, and @entity852 layers, with a 6 x 6 x 6 cm3 @entity852 cube inside the cork representing the @entity5 , was used to simulate a @entity2 treatment. Film dosimetry experiments were performed for an AP-PA irradiation technique with 8-MV or 18-MV beams. Dose distributions were compared for large square fields, small square fields, and intensity-modulated fields in which additional segments increase the dose at the edge of the field. The effect of target motion was studied by measuring the dose distribution for the solid cube, displaced with respect to the beams. RESULTS: For the 18-MV beam, the field sizes required to establish a sufficient target coverage are larger than for the 8-MV beam. For each beam energy, the mean dose in cork can significantly be reduced (at least a factor of 1.6) by decreasing the field size with 2 cm, while keeping the mean target dose constant. Target dose inhomogeneity for these smaller fields is limited if the additional edge segments are applied for 8% of the number of monitor units given with the open fields. The target dose distribution averaged over a motion cycle is hardly affected if the target edge does not approach the field edge to within 3 mm. CONCLUSIONS: For @entity2 treatment, a beam energy of 8 MV is more suitable than 18 MV. The mean lung dose can be significantly reduced by decreasing the field sizes of conformal fields. The smaller fields result in the same biological effect to the @entity5 if the mean target dose is kept constant. Intensity modulation can be employed to maintain the same target dose homogeneity for these smaller fields. As long as the target (with a 3 mm margin) stays within the field portal, application of a margin for target motion is not necessary.

Beam intensity modulation to reduce the field sizes for conformal XXXX : a dosimetric study.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity852 :: ('MESH:D011137', 'Chemical') :: ['polystyrene'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer', 'lung tumors']
@entity2 :: (MESH:D008175,Disease) :: ['irradiation of lung tumors']
