To compare the safety profiles of TheraSphere(  ) (glass) and SIR-Spheres(  ) (resin) Y90 microspheres for the treatment of @entity157 . A systematic review was conducted using the databases MEDLINE, Embase, and Cochrane Trials Register to identify all relevant studies. Baseline characteristics and adverse events of all grades related to @entity344 were collected along with commonly reported outcomes related to @entity887 . For all outcomes, data from each study were tabulated for each intervention. Adverse events and @entity1 were summed across studies on TheraSphere(  ) and SIR-Spheres(  ), respectively, and the resulting proportion of @entity1 experiencing an outcome for both interventions was calculated. Thirty-one observational studies were included in the review. In the adverse events of all grades, more @entity1 treated with resin microspheres reported @entity2275 , @entity99 , @entity2679 , @entity1578 , and @entity1143 . @entity1 treated with resin microspheres also had more hepatobiliary adverse events of grade 3 or higher. In the events related to @entity887 , glass microspheres exhibited a similar safety profile compared to resin microspheres. Ascites and @entity390 grade 3 or higher were recorded more frequently with glass microsphere treatment. Based on this review of the published literature, glass microspheres exhibit a safety profile with fewer gastrointestinal and pulmonary adverse events compared to resin microspheres in the treatment of @entity157 .

Comparison of the Adverse Event Profile of TheraSphere(  ) with SIR-Spheres(  ) for the Treatment of Unresectable XXXX : A Systematic Review.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1143 :: ('MESH:D010996', 'Disease') :: ['pleural effusion'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal, hepatobiliary, and respiratory systems'] @entity1578 :: ('MESH:D017093', 'Disease') :: ['hepatic failure'] @entity887 :: ('MESH:D004617', 'Disease') :: ['post-embolization syndrome'] @entity2679 :: ('MESH:D002764', 'Disease') :: ['cholecystitis'] @entity157 :: ('MESH:D006528', 'Disease') :: ['hepatocellular carcinoma'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic encephalopathy'] @entity2275 :: ('MESH:D013276', 'Disease') :: ['gastric ulcers']
@entity157 :: (MESH:D006528,Disease) :: ['Hepatocellular Carcinoma']
