BACKGROUND: The decision to take @entity34 ( @entity34 ) is a choice many @entity1 encounter when entering menopause. The purpose of this study was to examine the choice to take @entity34 while participating in a lifestyle intervention to reduce cardiovascular risk through the menopause. METHODS: The @entity1 's Healthy Lifestyle Project is a randomized clinical trial designed to examine whether a behavioral lifestyle intervention can decrease the expected rise in cardiovascular risk through the menopause. @entity1 (N = 535) completed questionnaires and were interviewed regarding menopausal symptoms, menopausal status, hot flashes, and @entity34 use at baseline and 54 months. RESULTS: The intervention was successful in preventing risk elevation through the 54-month visit. At the final visit, there was no difference between the intervention and control groups in the percentage who had become postmenopausal (32.9% vs 35.0%, respectively), there was no difference between control and intervention with @entity34 use, with 31.2% reporting use of @entity34 , and there was no difference between groups with menopausal symptoms. The @entity1 started @entity34 an average of 6 months after they missed a period. Baseline risk factors did not predict @entity34 use at the 54-month visit. CONCLUSIONS: A sizable number of @entity1 reported @entity34 use. The decision to use @entity34 was not influenced by the lifestyle intervention or their baseline cardiovascular risk, and these @entity1 started @entity34 very early in the peri- to postmenopause. Further, weight loss in the perimenopause did not affect menopausal symptoms.

Hormone replacement therapy use and menopausal symptoms among XXXX participating in a behavioral lifestyle intervention.

@entity1 :: ('9606', 'Species') :: ['women', 'Women', 'Participants'] @entity34 :: ('MESH:D016609', 'Disease') :: ['HRT', 'hormone replacement therapy']
@entity1 :: (9606,Species) :: ['women']
