BACKGROUND: Few studies have examined samples of @entity1 with cannabis-induced @entity716 . AIMS: To establish whether cannabis-induced @entity914 are followed by development of persistent @entity716 conditions, and the timing of their onset. METHOD: Data on @entity1 treated for cannabis-induced @entity716 between 1994 and 1999 were extracted from the Danish Psychiatric Central Register. Those previously treated for any @entity716 were excluded. The remaining 535 @entity1 were followed for at least 3 years. In a separate analysis, the sample was compared with @entity1 referred for @entity161 -spectrum disorders for the first time, but who had no history of cannabis-induced @entity716 . RESULTS: @entity161 -spectrum disorders were diagnosed in 44.5% of the sample. New @entity716 episodes of any type were diagnosed in 77.2%. Male gender and young age were associated with increased risk. Development of @entity161 -spectrum disorders was often delayed, and 47.1% of @entity1 received a diagnosis more than a year after seeking treatment for a cannabis-induced @entity716 . The @entity1 developed @entity161 at an earlier age than @entity1 in the comparison group (males, 24.6 v. 30.7 years, females, 28.9 v. 33.1 years). CONCLUSIONS: Cannabis-induced @entity914 are of great clinical and prognostic importance.

Cannabis-induced @entity716 and subsequent XXXX -spectrum disorders: follow-up study of 535 incident cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia', 'Schizophrenia'] @entity716 :: ('MESH:D011605', 'Disease') :: ['psychotic', 'psychosis', 'psychotic symptoms'] @entity914 :: ('MESH:D011618', 'Disease') :: ['psychotic disorders']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
