The ability of a @entity5 to grow and eventually to infiltrate adjacent tissues requires a sufficient blood supply. Many @entity5 have been shown to induce @entity2295 . We asked whether it is possible to characterize @entity43 on the basis of vascularization and whether vascularization can be used to differentiate between benign and @entity5 . We examined 14 cases of benign @entity9296 and 18 @entity189 . The microvessels were identified by immunohistochemical staining of endothelial cells for factor VIII. They were counted within the most vascular area of a @entity5 (neovascular "hot spot") on a x 100 and a x 400 field. Mean vessel counts were 51.64 [ @entity2246 ( @entity2246 ), 5.7] in the benign @entity9296 and 131.05 ( @entity2246 , 6.7) in the group of @entity189 at a x 100 magnification. The mean microvessel counts per x 400 field were 14.4 ( @entity2246 , 1.9) in the benign and 33.7 ( @entity2246 , 3.45) in the @entity5 investigated. These differences were significant (t test for independent samples, P < 0.001). Since our study shows significantly fewer small blood vessels in the benign @entity9296 than in the @entity5 , the histologically determinable vascular density may be the basis for imaging blood flow by means of color ultrasound.

The relevance of angiogenesis in benign and XXXX of the ovary: a quantitative histologic study.

@entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian epithelial tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignant tumors', 'malignant neoplasms'] @entity2295 :: ('MESH:D015861', 'Disease') :: ['neovascularization'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas'] @entity9296 :: ('MESH:D003537', 'Disease') :: ['cystadenomas'] @entity2246 :: ('MESH:D008661', 'Disease') :: ['standard error of the mean', 'SEM']
@entity189 :: (MESH:D002277,Disease) :: ['malignant epithelial tumors']
