BACKGROUND: Post-coronary artery bypass grafting @entity955 ( @entity3995 ) is associated with increased morbidity, mortality, and system costs. Few studies have @entity27 ( @entity27 ) as a risk factor for @entity3995 . We aimed to systematically review and synthesize the evidence associating @entity27 with @entity3995 . METHODS: We conducted a search of MEDLINE, EMBASE, Google Scholar, and Web of Science, as well as abstracts, conference proceedings, and reference lists until June 2014. Eligible studies were in English, were conducted in @entity1 , and assessed @entity27 with polysomnography (PSG) or a validated questionnaire. Two reviewers independently selected studies, with disagreement resolved by consensus. Piloted forms were used to extract data and assess risk of bias. RESULTS: Five prospective cohort studies were included (n  = 642). There was agreement in study selection (k statistic, 0.89; 95% confidence interval [CI], 0.75-1.00). @entity27 was associated with a higher risk of @entity3995 (odds ratio [OR], 1.86; 95% CI 1.24-2.80; P  = 0.003; I(2)  = 35%). We conducted 3 subgroup analyses. The associations increased for data that used PSG to assess @entity27 (OR, 2.34; 95% CI, 1.48-3.70), when severe @entity27 was included from 1 study (OR, 2.59; 95% CI, 1.63-4.11), and when adjusted analyses were pooled (OR, 2.38; 95% CI, 1.57-3.62; P < 0.001 in all), with no heterogeneity detected in any subgroup analysis (I(2) < 0.01% in all). CONCLUSIONS: @entity27 was shown to be a strong predictor of @entity3995 .

Obstructive Sleep Apnea as a Predictor of XXXX After Coronary Artery Bypass Grafting: A Systematic Review and Meta-analysis.

@entity1 :: ('9606', 'Species') :: ['humans'] @entity3995 :: ('8850', 'Gene') :: ['PCAF'] @entity27 :: ('MESH:D020181', 'Disease') :: ['explored obstructive sleep apnea', 'OSA'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation']
@entity955 :: (MESH:D001281,Disease) :: ['Atrial Fibrillation']
