OBJECTIVE: Awake craniotomy (AC) in @entity75 has allowed an improvement of both oncologic and functional results. However, intraoperative @entity410 (IOSs) were reported as a cause of failure of AC. Here, we analyze the incidence, risk factors, and consequences of IOSs in a prospective cohort of 374 ACs without electrocorticography (ECoG). METHODS: We performed a prospective study including all @entity1 who underwent AC for an intra-axial supratentorial cerebral lesion from 2009-2014 in our department. Occurrence of IOS was analyzed with respect to medical and @entity302 history, @entity5 characteristics, operative technique, and postoperative outcomes. RESULTS: The study comprised 374 @entity1 with a major incidence of @entity11 (86%). Most of the @entity1 (83%) had @entity302 history before surgery (20% had intractable @entity410 ). Preoperative mean Karnofsky performance scale (KPS) score was 91. IOSs occurred in 13 @entity1 (3.4%). All IOSs were partial @entity410 , which quickly resolved by irrigation with cold Ringer @entity880 . No procedure failed because of IOS, and the rate of aborted AC whatever the cause was nil. Mean stimulation current intensity for cortical and subcortical mapping was 2.25      0.6 mA. Presurgical @entity302 was not associated with a higher incidence of IOS. Three months after surgery, no @entity1 had severe or disabling permanent worsening, even within the IOS group (mean KPS score of 93.7). CONCLUSIONS: AC for intra-axial @entity75 can be safely and reproducibly achieved without ECoG, with a low rate of IOS and excellent functional results, even in @entity1 with preoperative @entity302 .

Low Rate of Intraoperative XXXX During Awake Craniotomy in a Prospective Cohort with 374 @entity75 : Electrocorticography Is Not Mandatory.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity75 :: ('MESH:D001927', 'Disease') :: ['brain lesion', 'brain lesions'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity11 :: ('MESH:D005910', 'Disease') :: ['low-grade glioma'] @entity302 :: ('MESH:D004827', 'Disease') :: ['refractory epilepsy', 'epilepsy', 'intractable epilepsy'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate']
@entity410 :: (MESH:D012640,Disease) :: ['Seizures']
