@entity43 screening in the general population has been performed using ultrasound examination of the female pelvis and serum @entity5 marker determinations. Ultrasound examinations, particularly transvaginal sonography (TVS), have been advocated as potentially useful modalities. Investigators from the University of Kentucky (Lexington, KY) and Hirosaki University (Hirosaki, Japan) have recently published results from ultrasound-based @entity43 screening studies. The Kentucky trial screened 14,469 @entity1 using TVS on an annual basis. One hundred eighty @entity1 underwent surgery, and 17 @entity43 were detected, 11 of which were invasive epithelial lesions. The Hirosaki trial reported the results of an ultrasound-based screening study among 51,550 @entity1 who were first-time @entity1 . Three hundred twenty-four @entity1 underwent surgery, and 22 @entity43 were detected. In each of these trials, the positive predictive value of gray-scale sonography was low. Morphologic @entity5 indexing and Doppler examinations have both been proposed as potential second-line studies, which could increase the positive predictive value of gray-scale ultrasound. A review of these techniques is presented. At present, @entity43 screening in the general population using ultrasound examinations is an experimental technique. Further studies are needed to determine whether second-line testing can improve the positive predictive value of gray-scale sonography such that asymptomatic @entity1 do not undergo unnecessary surgery for benign masses.

Ultrasound screening for the early detection of XXXX .

@entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian cancers', 'ovarian cancer', 'Ovarian cancer'] @entity1 :: ('9606', 'Species') :: ['participants', 'women'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor']
@entity43 :: (MESH:D010051,Disease) :: ['ovarian cancer']
