UNASSIGNED: The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to @entity1 seen in their own clinical practice.A 46-year-old premenopausal @entity1 with a body mass index of 21 was found on screening mammography to have a new, approximately 1-cm spiculated mass with associated @entity730 in the upper outer quadrant of the left breast. Stereotactic core biopsy showed a focus of invasive @entity189 , strongly positive for @entity172 and @entity1420 receptors and negative for @entity1 @entity1722 , with associated @entity513 in situ. Clinical examination revealed no palpable mass or @entity3329 . She underwent a left lumpectomy with seed localization and sentinel lymph node biopsy. Final pathology revealed an 8-mm well-differentiated @entity189 without @entity3 and intermediate grade @entity513 in situ. The margins were clear, and three sentinel lymph nodes were negative for @entity3 . The 21-gene recurrence score was 10, suggesting a 7% risk of 10-year distant recurrence with adjuvant endocrine treatment. After the completion of adjuvant radiotherapy (42.50 Gy in 16 fractions to the breast), the @entity1 has returned for a follow-up visit. She is a professional violinist and would like to know what she can do to prevent @entity4269 on her upcoming flight to Vienna.

XXXX Precautions: Time to Abandon Old Practices?

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'human', 'patient'] @entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['axillary lymphadenopathy'] @entity1420 :: ('MESH:D011374', 'Chemical') :: ['progesterone'] @entity4269 :: ('MESH:D008209', 'Disease') :: ['lymphedema'] @entity189 :: ('MESH:D002277', 'Disease') :: ['duct carcinoma', 'invasive carcinoma'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcifications'] @entity513 :: ('MESH:D044584', 'Disease') :: ['ductal carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'lymphovascular invasion'] @entity1722 :: ('2064', 'Gene') :: ['epidermal growth factor receptor 2']
@entity4269 :: (MESH:D008209,Disease) :: ['Lymphedema']
