BACKGROUND/OBJECTIVE: Advanced @entity191 is often associated with @entity73 and frequent falls. We describe a suggestive case report of @entity191 associated with @entity73 ( @entity73 ) and falls. The aim of our study was to test alteration in balance potentially related to use of acetylcholinesterase inhibitor (AchEI). We address this hypothesis after keeping the @entity1 in stable dosage of @entity935 agonist. METHODS/MEASUREMENTS: We describe an initial pharmacological management in a 78-year-old @entity1 affected by @entity191 ( @entity191 ) associated with @entity73 ( @entity73 ) and history of falls. The diagnosis of @entity191 was also confirmed by SPECT with DATSCAN, after CT-brain exclusion of potential other causes of the symptoms. Cognitive and motor performances of the @entity1 were initially evaluated by Mini Mental Examination State Examination (MMSE), Short Physical Performance Battery (SPPB) and Romberg test. We also recorded gait parameters using an accelerometer, while balance and stability were assessed by stabilometric platform with open and closed eyes. We repeated cognitive and motor tests and gait and balance evaluation after stable dosage of @entity935 agonist before and after introduction of AchEI. RESULTS: After starting @entity935 agonist therapy, there was a significant improvement in gait parameters (speed, stride/min, stride length, swing duration, and decrease in gait cycle duration and rolling duration). When stable dosage of @entity935 agonist was reached, AchEI was introduced obtaining not only a significant improvement of cognitive performance, but also a significant positive change in balance. CONCLUSION AND RELEVANCE: We hypothesize that AchEI could improve stability, balance and postural instability in addition to cognitive performance in @entity191 with @entity73 .

XXXX ( @entity191 ) with dementia and falls is improved by AChEI? A preliminary study report.

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment', 'MCI', 'MCI and balance deficits', 'mild cognitive impairment'] @entity935 :: ('MESH:D004298', 'Chemical') :: ['dopamine'] @entity191 :: ('MESH:D010300', 'Disease') :: ['Parkinson disease', 'PD']
@entity191 :: (MESH:D010300,Disease) :: ['Parkinson's disease']
