SETTING: Thirteen @entity284 maintenance treatment (MMT) clinics across Yunnan, the province with the highest @entity1 @entity465 virus (HIV) burden in China. OBJECTIVES: To determine, among @entity645 -negative @entity1 on MMT, the proportion lost to follow-up (defined as those who missed the 6-monthly follow-up examination), factors associated with loss to follow-up (LFU), @entity645 seroconversion rate and factors associated with seroconversion. DESIGN: Prospective cohort study from October 2008 to April 2011. All @entity1 were administered a pre-tested structured questionnaire to capture associated factors and offered @entity645 testing every 6 months.   (2) test and log-binomial regression were used for data analysis. RESULTS: Of 1146 @entity1 , 541 (47%) were lost to follow-up in 2.5 years. Factors associated with higher LFU proportion include <6 months of previous MMT, inconvenient location of the MMT clinic and average @entity284 dose    60 mg/day, with adjusted relative risks (RRs) of respectively 1.4 (95%CI 1.2-1.5), 1.2 (95%CI 1.0-1.4) and 1.1 (95%CI 1.0-1.3). The overall @entity645 seroconversion rate was 6.6 (95%CI 3.7-11.0) per 1000 @entity1 -years. Not living with a partner contributed to higher @entity645 rates, with an adjusted RR of 3.6 (95%CI 1.0-12.8). CONCLUSION: The retention rate of MMT @entity1 in Yunnan was not satisfactory. Decentralising service delivery in the community and making directly observed treatment more convenient has the potential to improve retention.

Retention and XXXX seroconversion among drug users on @entity284 maintenance treatment in Yunnan, China.

@entity1 :: ('9606', 'Species') :: ['participants', 'human', 'person'] @entity465 :: ('MESH:D007153', 'Disease') :: ['immunodeficiency'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity284 :: ('MESH:D008691', 'Chemical') :: ['methadone']
@entity645 :: (57667,Species) :: ['HIV']
