OBJECTIVES: To perform an analysis of oral baclofen dosage in @entity1 with traumatic @entity1566 over time and to ascertain the clinical determinants of long-term baclofen dosage trends. STUDY DESIGN: Retrospective cohort study of @entity1 records from the PM_R units at the Johns Hopkins Bayview Medical Center and the Johns Hopkins Hospital. SUBJECTS: A total of 115 PM_R @entity1 suffering @entity1566 due to @entity130 leading to either complete or incomplete @entity912 . The modes of injury included were @entity64 ( @entity64 ) (n=39), gunshot wounds (GSW) (n=55), falls (n=17), diving (n=2), workplace (n=1) and swimming (n=1) accidents. The location of injury in the spinal cord was categorized into either cervical (n=52), thoracic (n=59), lumbar (n=2), or unspecified (n=2). RESULTS: From time of injury, an aggregate of all dosage assignments for each @entity1 demonstrated a significant yearly increase in baclofen dosage (1.26mg/year, p  <0.01). Baclofen dosage for @entity64 cases were seen to rise at 4.99mg/year (p  <0.0001). Kaplan-Meier analysis revealed that GSW @entity1 received their first baclofen dosage earlier than @entity64 @entity1 (log-rank p  <0.05, unadjusted). CONCLUSIONS: We observed a marginal increase in baclofen dosage over nearly 25 years in a single provider's @entity1 database and observed different timings of first dose between two causes of traumatic SCI. These results provide an estimate of baclofen dosage trends over time after @entity1566 and may be useful for @entity1 counseling or as a method to assess costs of providing SCI @entity1 care.

Baclofen dosage after traumatic XXXX : A multi-decade retrospective analysis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['MVA', 'motor vehicle accidents'] @entity1566 :: ('MESH:D013119', 'Disease') :: ['spinal cord injuries', 'spinal cord injury'] @entity912 :: ('MESH:D010243', 'Disease') :: ['paralysis'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity1566 :: (MESH:D013119,Disease) :: ['spinal cord injury']
