BACKGROUND: Resistance to commonly used antibiotics by Enterococci causing @entity580 is of concern, which necessitates judicious, responsible and evidence-based use of antibiotics. The present study was conducted to review the prevalence and identify therapeutic options for nosocomial @entity281 in our tertiary care hospital. MATERIALS AND METHODS: Isolates identified by morphological and biochemical characteristics were tested for antibiotic susceptibility using Kirby-Bauer method. RESULT: 153 of 2096 culture positive clinical samples comprised of 101 urine, 30 wound swab/pus, 13 blood and 09 high vaginal swab isolates were identified as @entity797 (90.85%), @entity6375 (8.50%) and @entity797 gallinarum (0.65%). Enterococci accounted for 8.45%, 4.53%, 4.23%, 4.43% of urinary, wound swab or pus, blood, high vaginal swab isolates respectively, causing 7.3% of all @entity580 . Significant number of Enterococci isolated from nosocomial urinary tract infection (66.01%) and wound infections (19.6%) were multidrug resistant (MDR). Although all isolates were sensitive to @entity2176 and @entity5136 , resistance to @entity2929 (71.24%) and @entity2177 (49.67%) was frequently observed. High-level @entity801 resistance was observed in 43.88%, and 61.53% of @entity797 and @entity6375 isolates respectively. Minimal inhibitory concentration of @entity2176 of all the isolates were  <=1  g/ml. 7% of the Enterococcal isolates were MDR strains and @entity2176 or @entity5136 were the only effective antibiotics. CONCLUSION: A combination of @entity2176 and/or @entity5136 were effective against Enterococci causing @entity580 in our tertiary care facility, nevertheless continuous and frequent surveillance for resistance patterns are necessary for judicious and evidence based use of antibiotics.

Antibiotic resistance pattern of Enterococci isolates from XXXX in a tertiary care hospital in Eastern India.

@entity801 :: ('MESH:D005839', 'Chemical') :: ['gentamicin'] @entity2176 :: ('MESH:D014640', 'Chemical') :: ['vancomycin'] @entity2929 :: ('MESH:D004917', 'Chemical') :: ['erythromycin'] @entity2177 :: ('MESH:D002939', 'Chemical') :: ['ciprofloxacin'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Enterococcal infections'] @entity797 :: ('1351', 'Species') :: ['Enterococcus faecalis', 'E. faecalis', 'Enterococcus'] @entity6375 :: ('1352', 'Species') :: ['E. faecium', 'Enterococcus faecium'] @entity580 :: ('MESH:D003428', 'Disease') :: ['nosocomial infections'] @entity5136 :: ('MESH:C098010', 'Chemical') :: ['linezolid']
@entity580 :: (MESH:D003428,Disease) :: ['nosocomial infections']
