SUMMARY: Plastic and cosmetic surgery is often performed as an ambulatory procedure, and @entity158 is often mild to moderate. @entity158 relief is central to @entity1 comfort and satisfaction. Analgesics used should ensure rapid onset and adequate @entity158 relief lasting a sufficiently long duration with minimal or no side effects. @entity1443 is well tolerated by @entity1 , efficacious, and associated with only minor side effects, when used in the minimal effective doses. @entity32 ( @entity32 ) are more efficacious, having lower numbers needed to treat compared with @entity1443 , but have several side effects and contraindications. However, when used in the correct doses in healthy @entity1 , @entity32 are excellent for @entity158 management with one caveat that there is an increased risk for oozing or @entity548 . In contrast, cyclooxygenase inhibitors (Coxibs) are equally efficacious as @entity32 but have the added advantage that they have minimal or no effect on platelet function, and therefore, the risk for @entity548 complications is minimal. However, there has been some concern about the risk of vascular events in @entity1 with @entity741 , specifically when using Coxibs, but even some @entity32 , for example, diclofenac. In conclusion, @entity1443 should be given postoperatively to all @entity1 undergoing plastic surgical procedures. For @entity1 undergoing moderately invasive surgery, the addition of Coxibs to @entity1443 would be an advantage except in the @entity1 with @entity741 where @entity32 could have a place in management of @entity158 . Side effects and contraindications of @entity32 , however, restrict their use to the healthy @entity1 with mild comorbidities.

XXXX , nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 selective inhibitors: an update.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['NSAIDs', 'Nonsteroidal anti-inflammatory drugs'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Good pain', 'pain'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['acetaminophen', 'Acetaminophen']
@entity1443 :: (MESH:D000082,Chemical) :: ['Acetaminophen']
