STUDY OBJECTIVES: To define the clinical profile of young adults with optimal low-density lipoprotein (LDL) @entity165 levels who present with acute @entity583 ( @entity583 ); to compare and contrast differences in the clinical profiles of young adults admitted to the hospital with @entity583 who have LDL @entity165 levels < or = 100 mg/dL and those with LDL @entity165 values > or = 160 mg/dL; and to evaluate the clinical outcomes for the two groups at 1 year. DESIGN: A retrospective chart review was conducted on all young @entity1 (55 years) and @entity1 (65 years) admitted to the hospital for @entity583 within a 2-year period (n = 232). A history of cardiovascular risk factors and 1-year outcomes were obtained. SETTING: Rural community medical center serving a tri-state area in the midwestern United States. @entity1 : @entity1 were included in this analysis if (1) a lipid profile was drawn within 24 h of hospital admission and (2) the @entity1 was not receiving a statin medication on hospital admission. MEASUREMENTS AND RESULTS: Of the 183 @entity1 who met the inclusion criteria, as many as 68% (124 @entity1 ) had LDL @entity165 levels of < or = 130 mg/dL, 29% (53 @entity1 ) had LDL @entity165 level of < or = 100 mg/dL, and only 14% (26 @entity1 ) had LDL @entity165 levels of > or = 160 mg/dL. @entity1 were categorized into group 1 if their LDL @entity165 level was < or = 100 mg/dL and were categorized into group 2 if their LDL @entity165 level was > or = 160 mg/dL. In group 2, 92% of @entity1 were placed on a statin medication. By 1 year, the mean LDL @entity165 level had decreased from 188 to 106 mg/dL. The rate of coronary artery bypass graft and percutaneous coronary intervention procedures was similar between groups. Hospital readmission rates (43.4% vs 50%, respectively) and 1-year mortality rates (9% vs 8%, respectively) were not different between groups group 1 and 2. CONCLUSIONS: Young adults experiencing acute @entity583 typically have acceptable @entity165 levels (ie, < or = 130 mg/dL) or optimal values (ie, < or = 100 mg/dL). In those @entity1 with abnormal @entity165 levels, a combined strategy of aggressive intervention and adherence to secondary prevention protocols including lipid control is successful in improving outcomes.

XXXX in young adults with low-density lipoprotein @entity165 levels < or = 100 mg/dL: clinical profile and 1-year outcomes.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'patient', 'PATIENTS', 'men'] @entity583 :: ('MESH:D009203', 'Disease') :: ['MIs', 'myocardial infarctions'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity583 :: (MESH:D009203,Disease) :: ['Myocardial infarction']
