UNASSIGNED: Suboptimal uptake of the measles, mumps and @entity2462 (MMR) vaccine by certain socioeconomic groups may have contributed to recent large measles outbreaks in the UK. We investigated whether socioeconomic deprivation was associated with MMR vaccine uptake over 16 years. Using immunization data for 72 351 @entity1 born between 1995 and 2012 in Liverpool, UK, we examined trends in vaccination uptake. Generalized linear models were constructed to examine the relative effect of socioeconomic deprivation and year of birth on MMR uptake. Uptake of @entity60697 by age 24 months ranged between 82  5% in 2003 [95% confidence interval (CI) 81  2-83  7] and 93  4% in 2012 (95% CI 92  7-94  2). Uptake of @entity54810 by age 60 months ranged between 65  3% (95% CI 64  4-67  4) in 2006 and 90  3% (95% CI 89  4-91  2) in 2012. In analysis adjusted for year of birth and sex, @entity1 in the most deprived communities were at significantly greater risk of not receiving @entity60697 [risk ratio (RR) 1  70, 95% CI 1  45-1  99] and @entity54810 (RR 1  36, 95% CI 1  22-1  52). Higher unemployment and lower household income were significantly associated with low uptake. Contrary to concerns about lower MMR uptake in affluent families, over 16 years, @entity1 from the most socioeconomically deprived communities have consistently had the lowest MMR uptake. Targeted catch-up campaigns and strategies to improve routine immunization uptake in deprived areas are needed to minimize the risk of future measles outbreaks.

Effect of socioeconomic deprivation on uptake of measles, mumps and XXXX vaccination in Liverpool, UK over 16 years: a longitudinal ecological study.

@entity1 :: ('9606', 'Species') :: ['children'] @entity2462 :: ('MESH:D012409', 'Disease') :: ['rubella'] @entity54810 :: ('54842', 'Gene') :: ['MMR2'] @entity60697 :: ('374868', 'Gene') :: ['MMR1']
@entity2462 :: (MESH:D012409,Disease) :: ['rubella']
