BACKGROUND/PURPOSE: Endoscopic submucosal dissection (ESD) is an advanced endoscopic procedure to resect early @entity1820 . It is technically more difficult and risky when used to treat early @entity5 . We report our experiences related to performing ESD for early esophageal @entity5 . The efficacy, complications, and outcome were also analyzed. METHODS: From December 2007 to April 2010, 22 @entity1 with documented early esophageal @entity5 underwent ESD. All @entity1 completed a meticulous endoscopic examination using conventional endoscopy followed by narrow-band imaging. Lugol's staining was performed to identify the margin of the suspicious lesion. Insulation-tipped diathermic knife 2 was used for ESD. RESULTS: A total of 26 @entity1313 (including 13 @entity5 with high-grade @entity1141 , 12 @entity5 with @entity957 , and one @entity5 with @entity420 ) in 22 @entity1 were enrolled. All @entity1 were @entity1 . The mean age was 47.6    8.6 years (range, 30-68 years). The mean size of @entity5 was 33.7    21.7 mm (range, 8-80 mm). ESD was performed for 24 lesions in 20 @entity1 . The mean size of resected specimens was 43.1    19.2 mm (range, 15-90 mm). The mean operation time was 92.7    69 minutes (range, 30-310 minutes). There were three ESD-related complications, including one with delayed @entity548 , one with @entity9285 , and one with perforation. Two @entity1 received additional operations after ESD due to deep submucosal invasion by @entity5 . Three lesions in two @entity1 (12.5%) developed post-ESD esophageal stricture that needed repeated endoscopic bougination. There was no procedure-related mortality. No local recurrence was found during the follow-up period. CONCLUSION: ESD is a promising local curative treatment option for early esophageal @entity5 in Taiwan. However, this procedure may result in complications that are worth noting, especially post-ESD esophageal stricture. Education regarding this procedure and more hands-on training will facilitate endoscopists to improve the outcomes of @entity1 undergoing this procedure.

Endoscopic submucosal dissection for early esophageal XXXX : a single center experience in South Taiwan.

@entity1 :: ('9606', 'Species') :: ['men', 'patients'] @entity9285 :: ('MESH:D013352', 'Disease') :: ['subcutaneous emphysema'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['neoplastic lesions'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors', 'cancer', 'esophageal tumors', 'neoplasia', 'neoplasm'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity1820 :: ('MESH:D005770', 'Disease') :: ['gastrointestinal neoplasm'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasia']
@entity5 :: (MESH:D009369,Disease) :: ['neoplasia']
