BACKGROUND: The aim of this study was to assess whether laparoscopic appendectomy (LA) for @entity532 ( @entity532 ) effectively reduces the incidence of @entity260 and improves various measurements of postoperative recovery in adults compared with @entity1538 ( @entity1538 ). METHODS: This single-center, randomized controlled trial was performed in the Nagoya Daini Red Cross Hospital. @entity1 diagnosed as having @entity532 with @entity298 or @entity733 formation were eligible to participate and were randomly assigned to an LA group or an @entity1538 group. The primary study outcome was development of @entity166 , especially @entity281 ( @entity281 ), within 30  days of surgery. RESULTS: Between October 2008 and August 2014, 81 @entity1 were enrolled and randomly assigned with a 1:1 allocation ratio (42, LA; 39, @entity1538 ). All were eligible for study of the primary endpoint. Groups were well balanced in terms of @entity1 characteristics and preoperative levels of C-reactive protein. @entity281 occurred in 14 LA group @entity1 (33.3  %) and in 10 @entity1538 group @entity1 (25.6  %) (OR 1.450, 95  % CI 0.553-3.800; p  =  0.476). Overall, the rate of @entity260 , including incisional or organ/space @entity281 and stump leakage, did not differ significantly between groups. No significant differences between groups were found in hospital stay, duration of drainage, analgesic use, or parameters for postoperative recovery except days to walking. CONCLUSION: These results suggested that LA for @entity532 is safe and feasible, while the distinguishing benefit of LA was not validated in this clinical trial.

Laparoscopic versus open surgery for XXXX in adults: a randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open appendectomy', 'OA'] @entity532 :: ('MESH:D003925', 'Disease') :: ['CA', 'complicated appendicitis'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity281 :: ('MESH:D007239', 'Disease') :: ['surgical site infection', 'SSI'] @entity733 :: ('MESH:D000038', 'Disease') :: ['abscess'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious complications'] @entity298 :: ('MESH:D010538', 'Disease') :: ['peritonitis']
@entity532 :: (MESH:D003925,Disease) :: ['complicated appendicitis']
