UNASSIGNED: This cross-sectional study was to evaluate the levels of urinary liver-type @entity844 binding protein (u- @entity20506 pg/mg urine @entity1011 ratio) at different stages of @entity2316 and to see its correlation with other clinical parameters in South Indian @entity1 with @entity6 ( @entity6 ). A total of 65 (M: F; 42:23) @entity6 subjects were divided into three groups, and were compared with 13 (M: F; 3:10) nondiabetic controls. The study groups were as follows: normoalbuminuric (n = 22), microalbuminuric (n = 22) and macroalbuminuric (n = 21). Estimated glomerular filtration rate (eGFR) was calculated using Cockcroft and Gault formula. u- @entity20506 levels in spot urine samples were measured with a solid phase enzyme linked immunosorbent assay. This study showed that u- @entity20506 levels were undetectable in healthy controls and was very low in the normoalbuminuric subjects. Elevated levels of u- @entity20506 are evident from the microalbuminuric stage indicating @entity8 . The levels of u- @entity20506 increased gradually with declining renal function. Geometric mean (95% confidence interval) for normoalbuminuria was 0.65 (0.47-0.97), microalbuminuria was 0.99 (0.55-1.97) and macroalbuminuria was 5.16 (1.8-14.5), (P = 0.005). In conclusion, u- @entity20506 levels were elevated in @entity1 with reduced eGFR and showed a positive correlation with systolic blood pressure and protein to @entity1011 ratio in the total study subjects.

Clinical significance of urinary liver-type @entity844 binding protein at various stages of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity844 :: ('CHEBI:35366', 'Chemical') :: ['fatty acid'] @entity8 :: ('MESH:D007674', 'Disease') :: ['tubular damage'] @entity6 :: ('MESH:D003920', 'Disease') :: ['T2DM', 'type 2 diabetes mellitus'] @entity2316 :: ('MESH:D003928', 'Disease') :: ['diabetic nephropathy'] @entity20506 :: ('2168', 'Gene') :: ['LFABP'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity8 :: (MESH:D007674,Disease) :: ['nephropathy']
