AIMS: @entity1534 ( @entity1534 ) eradication rate varies according to the treatment regimen used and other factors, e.g. antimicrobial resistance and @entity1 compliance. The aim of the present study was to evaluate the influence of @entity1 counselling and follow-up on @entity1534 eradication rates and to document the effectiveness of a 1 week eradication regimen consisting of @entity10042 (30 mg once daily), @entity115 (1 g twice daily) and @entity4581 (500 mg twice daily). METHODS: Seventy-six dyspeptic @entity1 , who at endoscopy were found to have @entity3621 , @entity9317 or @entity1066 , and a positive @entity1534 urease test, were recruited. @entity1 were randomly assigned to an intervention group (n = 38) or a control group (n = 38). Intervention @entity1 received their medicines via the hospital pharmacy and were counselled (and followed up) by a hospital pharmacist. Control @entity1 were given a standard advice sheet and referred to their GP who prescribed the same therapy. RESULTS: Intervention @entity1 exhibited a statistically significant improvement in the @entity1534 eradication rate (94.7% vs 73.7%; P = 0.02) and compliance (92.1% vs 23.7; P < 0.001). Of the 64 @entity1534 eradicated @entity1 , 62 were able to eliminate their antisecretory medication compared with only 12 of the @entity1534 persistent @entity1 (P < 0.001). A pharmacoeconomic evaluation indicated that counselling and follow-up reduced the direct costs of eradication by approximately 30 UK pounds per @entity1 . CONCLUSIONS: Structured @entity1 counselling and follow-up can have a significant effect on @entity1534 eradication rates and should be a routine part of therapy.

Management of XXXX eradication--the influence of structured counselling and follow-up.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity115 :: ('MESH:D000658', 'Chemical') :: ['amoxicillin'] @entity4581 :: ('MESH:D017291', 'Chemical') :: ['clarithromycin'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulceration'] @entity10042 :: ('MESH:C058687', 'Chemical') :: ['lansoprazole'] @entity3621 :: ('MESH:D005756', 'Disease') :: ['gastritis'] @entity1534 :: ('210', 'Species') :: ['H. pylori', 'Helicobacter pylori'] @entity9317 :: ('MESH:D004382', 'Disease') :: ['duodenitis']
@entity1534 :: (210,Species) :: ['Helicobacter pylori']
