BACKGROUND AND OBJECTIVES: The aim of this study was to test the effects of individual schema therapy (ST) for @entity1 with @entity308 . METHODS: Using a multiple-baseline single case series design, @entity1 with chronic @entity308 (N  =  25) first entered a 6-24 weeks baseline phase; this phase functioned as a no-treatment control condition. Then, @entity1 started a 12 week exploration phase during which symptoms and underlying schemas were explored; this phase functioned as an attention control condition. Next, @entity1 received up to 65 sessions of individual ST. The Beck Depression Inventory II (BDI-II) and the Quick Inventory of Depressive Symptomatology (QIDS) were the primary outcome measures. The BDI-II was assessed once a week during all phases of the study resulting in 100 repeated assessments per @entity1 on average. Mixed regression analysis was used to contrast change in symptoms during the intervention with change in symptoms during the baseline and exploration control phases. RESULTS: When compared to the no-treatment control period, the intervention had a significant, large effect on @entity308 (Cohen's d BDI-II  =  1.30; Cohen's d QIDS  =  1.22). Effects on secondary continuous outcomes were moderate to large. LIMITATIONS: The small sample size and lack of a control group. CONCLUSIONS: These findings provide evidence that ST might be an effective treatment for @entity1 with @entity308 .

Schema therapy for XXXX : Results of a multiple single case series.

@entity1 :: ('9606', 'Species') :: ['patients', 'participant'] @entity308 :: ('MESH:D003866', 'Disease') :: ['chronic depression', 'depressive symptoms', 'major depressive disorder']
@entity308 :: (MESH:D003866,Disease) :: ['chronic depression']
