OBJECTIVE: To determine the effect of instillation of normal saline before suctioning on @entity26 saturation, heart rate, and blood pressure in @entity1 with @entity358 . METHODS: A prospective randomized controlled trial was conducted in the surgical, medical, and burn/ @entity130 ICUs of an academic medical center. Eighteen @entity1 and 11 @entity1 (mean age = 60 years) receiving mechanical ventilation who met the criteria for @entity358 were randomly assigned to 2 groups. One group had instillation of a 5-mL bolus of normal saline before suctioning; the other did not. Suctioning was done as needed during an 8-to 12-hour period. @entity26 saturation, heart rate, and blood pressure were measured noninvasively immediately before and after suctioning, at 1-minute intervals for 5 minutes after suctioning, and at 10 minutes after suctioning. RESULTS: Instillation of normal saline had an adverse effect on @entity26 saturation, which worsened over time. Differences in saturation between the 2 groups were significant at 4, 5, and 10 minutes after suctioning. Differences in heart rate and blood pressure were not significant. CONCLUSION: Instillation of normal saline before suctioning has an adverse effect on @entity26 saturation and should not be used routinely in @entity1 receiving mechanical ventilation who have @entity358 .

Instillation of normal saline before suctioning in @entity1 with XXXX : a prospective randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen', 'Oxygen'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary infections', 'pulmonary infection'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity358 :: (MESH:D008171,Disease) :: ['pulmonary infections']
