PURPOSE: To report on the incidence of @entity174 in @entity1 treated with Intensity Modulated Radiotherapy (IMRT) for locally advanced @entity1149 ( @entity1149 ) and to analyse the association with clinical and dosimetric parameters. @entity1 AND METHODS: Between 2007 and 2012, 524 @entity1 treated with    51Gy were retrospectively analysed for the incidence of @entity174 ( @entity174 ). Clinical parameters were assessed. In addition, a case control study in 50 @entity1 was performed to study the association between the radiotherapy dose and fractured vertebrae. RESULTS: Three hundred and thirty-six @entity1 were eligible for analyses. Twenty-eight @entity1 (8%) were observed with @entity174 at a median follow up of 12months. Age was significantly higher in the group with @entity174 (p<0.01). After balancing age, the mean vertebrae dose was most significantly associated with @entity174 of the vertebrae (p<0.01). CONCLUSION: @entity174 was observed in 8% of the @entity1 with locally advanced @entity1149 . @entity138 dose was associated with the occurrence of @entity174 .

Fractures of thoracic vertebrae in @entity1 with locally advanced XXXX treated with intensity modulated radiotherapy.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small cell lung carcinoma'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures', 'vertebral fractures', 'thoracic vertebral fractures', 'VF'] @entity138 :: ('MESH:C563738', 'Disease') :: ['RT']
@entity1149 :: (MESH:D002289,Disease) :: ['non-small cell lung carcinoma']
