AIMS: Few researchers have studied whether @entity6 itself is responsible for high rates of disability or mortality, or if factors associated with @entity6 contribute importantly. We estimated associations of @entity6 , @entity299 , @entity28 , and physical inactivity with life expectancy (LE), the proportion of life with disability (DLE), and disability in the last year of life. METHODS: Data were from the Panel Study of Income Dynamics (1999-2011 and 1986, African American and white @entity1 and @entity1 ages 55+, n=1,980, 17,352 @entity1 -years). Activities of daily living defined disability. Multinomial logistic Markov models estimated disability transition probabilities adjusted for age, sex, race/ethnicity, education, and the health factors. Microsimulation measured outcomes. RESULTS: White @entity1 and @entity1 exemplify results. LE was, for @entity1 : 3.5 years less with @entity6 than without (95% confidence interval, 3.1-4.0), 11.1 less (10.3-12.0) adding @entity299 , 21.9 less with all factors (15.3-28.5), all p<0.001. Corresponding results for @entity1 : 1.7 years (0.9-2.3, not significant), 8.2 (6.8-9.5) and 18.1 (15.6-20.6), both p<0.001. DLE was, for @entity1 : 23.5% (21.7-25.4) with no risk factors, 27.1% (25.7-28.6) with @entity6 alone, 34.6% (33.1-36.1) adding @entity299 , 52.9% (38.9-66.8) with all factors, all p<0.001; for @entity1 : 13.2% (11.7-14.6), 16.3% (14.8-17.8, p<0.01); and 22.1% (20.5-23.7), 36.4% (25.0-47.8), both p<.001. Among @entity1 with @entity6 , those with other conditions were much less likely to have no disability in the final year of life. CONCLUSIONS: Much of the disability and mortality with @entity6 was due to @entity299 , @entity28 , and inactivity, risks that can be modified by health behaviors and medical care.

Active life expectancy of Americans with @entity6 : Risks of @entity299 , XXXX , and inactivity.

@entity1 :: ('9606', 'Species') :: ['women', 'person', 'people', 'men'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart disease']
@entity28 :: (MESH:D009765,Disease) :: ['obesity']
