OBJECTIVES: Describe the methodologies and study population of the @entity6 Outcomes in Veterans Study (DOVES). RESEARCH DESIGN AND METHODS: Prospective, multicenter, observational study of Southwestern veterans with stable, @entity2690 -treated @entity164 2 @entity6 . Subjects were randomly selected from pharmacy records and were required to be using at least one long-acting @entity2690 preparation daily. Baseline psychosocial evaluations included @entity159 , social and cultural barriers to care, self-care behaviors, and @entity455 risk factors. Clinical measurements included self-reported @entity455 , hemoglobin A1c (HbA1c), blood pressure, blood lipids, and body mass index (BMI). A subset of subjects completed a protocol of four times daily self-monitored blood @entity413 testing for 8 weeks. Subjects were followed for 12 months. Principal endpoints included glycemic control, the occurrence of @entity4053 , and control of @entity455 risk factors. RESULTS: We enrolled 338 subjects. The mean (+/-S.D.) age was 65.1+/-9.7 years and 3.8% were @entity1 . At baseline, over two-thirds of subjects reported @entity455 . Nearly three-quarters had limited physical activity. Among subjects younger than 65 years, 53% considered themselves disabled for work. Despite the high prevalence of @entity455 , 43.8% had an HbA1c >/=8.0%. Many subjects were sedentary, 62.1% had a BMI of 30 kg/m(2) or above, and 22.2% were still smoking. CONCLUSIONS: Detailed measurements of @entity159 , self-care behaviors, and risk factor control are feasible in this elderly, debilitated population. Although the prevalence of complications and self-rated disability was high, @entity455 risk factors were poorly controlled in a substantial proportion of subjects.

Risk factor management in stable, XXXX -treated @entity1 with @entity164 2 @entity6 : the @entity6 Outcomes in Veterans Study.

@entity1 :: ('9606', 'Species') :: ['women'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular disease', 'vascular disease complications'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetes'] @entity2690 :: ('3630', 'Gene') :: ['insulin'] @entity4053 :: ('MESH:D007003', 'Disease') :: ['hypoglycemia'] @entity164 :: ('MESH:D017827', 'Disease') :: ['Type'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity159 :: ('MESH:D013226', 'Disease') :: ['psychological status']
@entity2690 :: (3630,Gene) :: ['insulin']
