BACKGROUND AND PURPOSE: Silent @entity4798 are commonly seen on @entity2996 ( @entity2996 ) both in @entity1 with a first @entity64 and in healthy elderly @entity1 . These @entity1188 seem associated with an increased risk of @entity64 . It is unclear whether risk factors for silent @entity1188 differ from those for symptomatic @entity64 . We investigated the prevalence of, and cardiovascular risk factors for, silent @entity4798 . METHODS: The Rotterdam Scan Study is a population-based cohort study among 1077 @entity1 60 to 90 years of age. @entity1 underwent cerebral @entity2996 . We assessed cardiovascular risk factors by interview and physical examination. Associations between risk factors and presence of @entity1188 were analyzed by logistic regression and adjusted for age, sex, and relevant confounders. RESULTS: For 259 @entity1 (24%) 1 or more @entity1188 on @entity2996 were seen; 217 @entity1 had only silent and 42 had symptomatic @entity1188 . The prevalence odds ratio (OR) of both silent and symptomatic @entity1188 increased with age by 8% per year (95% CI, 1.06 to 1.10 and 1.04 to 1.13, respectively). Silent @entity1188 were more frequent in @entity1 (age-adjusted OR, 1.4; 95% CI, 1.0 to 1.8). @entity101 was associated with silent @entity1188 (age- and sex-adjusted OR, 2.4; 95% CI, 1.7 to 3.3), but @entity6 and smoking were not. CONCLUSIONS: Silent @entity4798 are 5 times as prevalent as symptomatic @entity4798 in the general population. Their prevalence increases with age and seems higher in @entity1 . @entity101 is associated with silent @entity1188 , but other cardiovascular risk factors are not.

Prevalence and risk factors of silent XXXX in the population-based Rotterdam Scan Study.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients', 'Participants', 'persons'] @entity4798 :: ('MESH:D020520', 'Disease') :: ['brain infarcts'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity101 :: ('MESH:D006973', 'Disease') :: ['Hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity2996 :: ('MESH:C564543', 'Disease') :: ['MRI', 'magnetic resonance imaging'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarcts']
@entity4798 :: (MESH:D020520,Disease) :: ['brain infarcts']
