BACKGROUND: @entity3528 ( @entity3528 ) is a common @entity74 in @entity1 with @entity177 . Despite the development of new therapeutic agents, a majority of @entity1 will require parathyroidectomy. The aim of this study was to evaluate total parathyroidectomy with auto-transplantation of trace amounts of parathyroid tissue as a surgical option in @entity5507 @entity3528 treatment. METHODS: Clinical data of 50 @entity3528 @entity1 who underwent total parathyroidectomy with auto-transplantation between January 2011 and December 2013 were reviewed retrospectively. Symptoms such as @entity158 and @entity174 , concentrations of intact parathyroid hormone (iPTH), levels of ionized @entity460 and serum @entity3151 , and activity of alkaline phosphatase were recorded before and after parathyroidectomy. RESULTS: After operation, signs of @entity111 , @entity158 and @entity425 was disappeared, iPTH level and serum @entity4613 concentration were declined markedly. No @entity260 were observed. Follow-up observation was around 28 months. One female @entity1 (2%) died 3 months after surgery due to @entity712 , and another @entity1 (2%) had persistent disease. All other @entity1 recovered during the follow-up period. CONCLUSIONS: Total parathyroidectomy with auto-transplantation of trace amounts of parathyroid tissue was considered to be a feasible, safe and effective surgical option for the treatment of @entity3528 .

Application of total parathyroidectomy with auto-transplantation for XXXX secondary hyperparathyroidism treatment.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures'] @entity5507 :: ('MESH:D014511', 'Disease') :: ['uremia'] @entity4613 :: ('D010710', 'Chemical') :: ['phosphate'] @entity3528 :: ('MESH:D006962', 'Disease') :: ['Secondary hyperparathyroidism', 'sHPT'] @entity425 :: ('MESH:D018908', 'Disease') :: ['muscle weakness'] @entity260 :: ('MESH:D011183', 'Disease') :: ['serious postoperative complications'] @entity177 :: ('MESH:D051437', 'Disease') :: ['chronic renal failure'] @entity111 :: ('MESH:D011537', 'Disease') :: ['pruritus'] @entity74 :: ('MESH:D030342', 'Disease') :: ['acquired disorder'] @entity158 :: ('MESH:D010146', 'Disease') :: ['bone pain'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity3151 :: ('MESH:D010758', 'Chemical') :: ['phosphorus']
@entity5507 :: (MESH:D014511,Disease) :: ['uremia']
