The purpose of @entity571 treatment is to improve @entity1 's @entity158 and quality of life. Non-steroidal anti-inflammatory drugs are the first choice but their effectiveness is questionable due to the risk of secondary @entity1819 and @entity177 . Intra-articular drugs are a safe and effective alternative to improve symptoms and function; they may delay surgery but we don't know if they are disease modifying. Our objective was to compare knee function and @entity158 in @entity1 with @entity571 until treatment is finished. Our hypothesis is that there is no difference in the results of both groups. MATERIAL AND METHODS: A prospective, simple, randomized non blinded trial where we studied two groups of @entity1 with knee @entity571 . Group 1 was treated with Collagen PVP and Group 2 received hylan GF-20. We gave @entity1 a subjective questionnaire of the International Knee Committee IKDC and @entity158 was measured using the visual analog scale at the beginning of treatment, after one month and after three months. RESULTS: Decrease in @entity158 measured with the visual analog scale is statistically significant in both groups, however, when comparing both groups we did not find differences. The results of the IKDC were the same in both groups, there was no difference except in baseline measurements and in the final result.

[Effectiveness of two intraarticular drugs in XXXX with knee arthrosis. Polymerized collagen versus hylan].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity571 :: ('MESH:D010003', 'Disease') :: ['osteoarthrosis'] @entity1819 :: ('MESH:D013272', 'Disease') :: ['gastric disease'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity1 :: (9606,Species) :: ['patients']
