OBJECTIVE: To determine the characteristics of @entity1642 ( @entity1642 ) lesions and their relative associations with the risk of clinical progression. MATERIALS AND METHODS: This HIPAA-compliant retrospective study was approved by our Institutional Review Board. Seventy-three @entity1 (age range, 19-95) were included after excluding @entity1 with post-traumatic @entity174 , @entity236 , @entity1843 , or underlying @entity5 . Two board-certified musculoskeletal radiologists classified morphologic findings including lesion diameter, associated @entity236 pattern, and associated cartilage/meniscus damage. Electronic medical charts were evaluated for symptoms, risk factors, and longitudinal outcomes, including total knee arthroplasty (TKA). Imaging characteristics were correlated with clinical findings, and comparison of outcome groups was performed using a regression model adjusted for age. RESULTS: The majority of @entity1 with @entity1642 were @entity1 (64.4%, 47/73), on average 10 years older than @entity1 (66.28        15.86 years vs. 56.54        10.39 years, p   =   0.005). The most common location for @entity1642 was the central weight-bearing surface of the medial femoral condyle; overlying full thickness cartilage loss (75.7%, 53/70) and @entity130 (94.1%, 64/68) were frequently associated. Clinical outcomes were variable, with 23.9% (11/46) requiring TKA. Cartilage WORMS score, adjacent cartilage loss, and @entity130 , in addition to decreased knee range of motion at presentation, were significantly associated with progression to TKA (p   <   0.05). CONCLUSIONS: @entity1642 are frequently associated with overlying cartilage loss and @entity130 . The extent of cartilage loss and @entity16 , in addition to loss of knee range of motion at the time of presentation, are significantly associated with clinical progression.

XXXX : associated clinical and morphological findings and impact on outcome.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity16 :: ('MESH:D009422', 'Disease') :: ['meniscal damage'] @entity1843 :: ('MESH:D010008', 'Disease') :: ['osteochondritis dissecans'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow infarct', 'bone marrow edema'] @entity1642 :: ('MESH:D015775', 'Disease') :: ['femoral condyle insufficiency fracture', 'FCIF'] @entity130 :: ('MESH:D014947', 'Disease') :: ['ipsilateral meniscal injury', 'contralateral meniscal injury']
@entity1642 :: (MESH:D015775,Disease) :: ['Femoral condyle insufficiency fractures']
