BACKGROUND: Left atrial (LA) size has been associated with adverse outcome in @entity1 after @entity583 . However, data about the occurrence of late LA enlargement and changes in LA function during follow-up are scarce. The purpose of the current study was to evaluate changes in LA size and function during 1-year follow-up. METHODS: The study population comprised 407 @entity1 with @entity583 who were treated with primary percutaneous coronary intervention. At baseline and 12 months, two-dimensional echocardiography was performed to assess LA volumes and function using speckle-tracking strain and strain rate. RESULTS: The mean age was 60    11 years, and most @entity1 were @entity1 (78%). LA maximal volume increased from 25    8 to 28    8 mL/m(2) (P < .001) from baseline to 1 year. Echocardiographic assessment at 1-year follow-up showed that 92 @entity1 (25%) had developed LA remodeling (defined as an increase of >= 8 mL/m(2) in LA maximal volume). On multivariate analysis, only LA maximal volume at baseline (odds ratio, 0.95; 95% confidence interval, 0.91-0.98; P = .003) and LA strain at baseline (odds ratio, 0.94; 95% confidence interval, 0.92-0.97; P < .001) were independent predictors of LA remodeling during follow-up. Interestingly in @entity1 without LA remodeling, no changes were observed in LA function during follow-up. However, in @entity1 with LA remodeling, LA function significantly worsened during follow-up. In line, LA strain and strain rate were significantly lower at 12 months compared with baseline (24    7% vs 27    6%, P < .001, and 1.8    0.5 vs 2.4    0.7 sec(-1), P < .001, respectively). CONCLUSIONS: LA remodeling occurred in 22% of @entity1 after @entity583 . In @entity1 without LA remodeling, no changes in LA function were observed, but in @entity1 with LA remodeling, LA function deteriorated significantly.

Comprehensive assessment of changes in left atrial volumes and function after ST-segment elevation XXXX : role of two-dimensional speckle-tracking strain imaging.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity583 :: ('MESH:D009203', 'Disease') :: ['acute myocardial infarction']
@entity583 :: (MESH:D009203,Disease) :: ['acute myocardial infarction']
