Background/Aims: Brain and bone @entity3 are common in @entity1 with @entity2 . The development of @entity3 is associated with poor survival in @entity2 @entity1 . Although @entity5 morphologic features on radiographs are routinely assessed for differentiation between benign and malignant lung nodules, they are not used to predict @entity3 . We assessed morphologic features of @entity420 with @entity79 on computed tomography (CT) to identify related factors for @entity3 . Methods: We performed a retrospective analysis of initial chest CT findings (size, type of contour, percentage of @entity39 , enhancement, presence or absence of @entity730 , and air cavity) from 2009 to 2010 of @entity1 with brain or bone @entity3 and compared the findings with those of @entity1 without @entity3 . Results: In total, 128 @entity1 were included (78 @entity1 , 52 @entity1 ; mean age 69 years; range, 36 to 87). Nineteen @entity1 had brain @entity3 and 32 had bone @entity3 . Morphologic features associated with brain @entity3 included size >=  50 mm (odds ratio [OR], 3.37; 95% confidence interval [CI], 1.24 to 9.17; p = 0.013), @entity39 >=  30% (OR, 4.51; 95% CI, 1.62 to 12.55; p =0.002), and presence of @entity730 (OR, 3.97; 95% CI, 1.16 to 13.55; p = 0.035). Morphologic features associated with bone @entity3 included @entity39 >=  30% (OR, 4.639; 95% CI, 1.98 to 10.82; p < 0.001) and T 3 to 4 stage (OR, 2.53; 95% CI, 1.07 to 6.00; p = 0.031). Conclusions: We found that @entity39 >=  30% was associated with @entity420 with @entity79 at initial chest CT morphologic feature. To validate these results, further research should be conducted.

Computed tomography morphologic features of @entity420 with XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcification'] @entity79 :: ('MESH:D001847', 'Disease') :: ['brain/bone metastasis', 'brain and bone metastasis'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity420 :: ('MESH:D000230', 'Disease') :: ['pulmonary adenocarcinomas', 'pulmonary adenocarcinoma']
@entity79 :: (MESH:D001847,Disease) :: ['brain/bone metastasis']
