A noninvasive test to prove @entity1690 is desired, because endoscopic manometry is technically demanding and not without risks. METHODS: 40 consecutive @entity1 (n = 20 @entity1 with, and n = 20 @entity1 without enzymatic @entity1448 ) with suspected SOD were investigated both by ultrasonography (US; 3.5 MHz) and by endoscopic manometry. SOD was suspected at US if the extrahepatic bile duct diameter was > or = 9 mm and a further increase (at least > 0.5 mm) was observed after intravenous ceruletide (0.3 micrograms/kg b.w.). SOD was verified manometrically by a sphincter of Oddi basal pressure > or = 40 mmHg. Endoscopic sphincterotomy was performed if SOD was diagnosed by manometry. Thereafter, all @entity1 were enrolled in a prospective follow-up (median: one year). RESULTS: At US SOD was suspected in eleven of 20 @entity1 with @entity1448 . SOD was confirmed manometrically in all of them but also in two further @entity1 (13 of 20 @entity1 with proven SOD). After EST twelve of 13 @entity1 remained free from biliary symptoms. In the 20 @entity1 without @entity1448 SOD was suspected at US in five @entity1 only. However, endoscopic manometry revealed SOD in eleven of 20 @entity1 and proved sonographically presumed SOD in only three of five @entity1 . After EST only three of eleven @entity1 remained asymptomatic during follow-up (p < 0.05 vs. @entity1 with @entity1448 ). Clinically important side effects were not observed after ceruletide administration, whereas postmanometry @entity788 was observed in three of 40 @entity1 . CONCLUSION: In @entity1 with recurrent symptoms after cholecystectomy and enzymatic @entity1448 SOD was reliably diagnosed by ultrasonography (sensitivity: 85%, specificity: 100%), and this finding may guide endoscopic sphincterotomy.

[Do ultrasound parameters allow diagnosis of biliary XXXX ?].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1690 :: ('MESH:D046628', 'Disease') :: ['sphincter of Oddi dysfunction'] @entity1448 :: ('MESH:D002779', 'Disease') :: ['cholestasis'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatitis']
@entity1690 :: (MESH:D046628,Disease) :: ['sphincter of Oddi dysfunction']
