BACKGROUND In the past decades, a large number of @entity23 ( @entity23 ) on the efficacy of @entity19316 injection combined with conventional antianginal drugs for @entity951 have been reported. However, these @entity23 have not been evaluated in accordance with PRISMA systematic review standards. The aim of this study was to evaluate the efficacy of @entity19316 injection as adjunctive therapy for @entity951 . MATERIAL AND METHODS The databases PubMed, Medline, Cochrane Library, Embase, Sino-Med, Wanfang Databases, Chinese Scientific Journal Database, Google Scholar, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, and the Chinese Science Citation Database were searched for published @entity23 . Meta-analysis was performed on the primary outcome measures, including the improvements of electrocardiography (ECG) and the @entity951 . Sensitivity and subgroup analysis based on the M score (the refined Jadad scores) were also used to evaluate the effect of quality, sample size, and publication year of the included @entity23 on the overall effect of @entity19316 injection. RESULTS Eleven @entity23 involving 870 @entity1 with @entity951 were selected in this study. Compared with conventional antianginal drugs alone, @entity19316 injection combined with antianginal drugs significantly increased the efficacy in symptom improvement (odds ratio [OR], 3.59; 95% confidence interval [CI]: 2.39 to 5.40) and in ECG improvement (OR, 3.42; 95% CI: 2.33 to 5.01). Sensitivity and subgroup analysis also confirmed that @entity19316 injection had better effect in the treatment of @entity951 as adjunctive therapy. CONCLUSIONS The 11 eligible @entity23 indicated that @entity19316 injection as adjunctive therapy was more effective than antianginal drugs alone. However, due to the low quality of included @entity23 , more rigorously designed @entity23 were still needed to verify the effects of @entity19316 injection as adjunctive therapy for @entity951 .

Efficacy of XXXX Injection as Adjunctive Therapy for Angina Pectoris: A Systematic Review and Meta-Analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity23 :: ('MESH:D007174', 'Disease') :: ['randomized controlled trials', 'RCTs'] @entity951 :: ('MESH:D000787', 'Disease') :: ['reductions in angina symptoms', 'angina pectoris'] @entity19316 :: ('MESH:C017953', 'Chemical') :: ['ligustrazine']
@entity19316 :: (MESH:C017953,Chemical) :: ['Ligustrazine']
