OBJECTIVE: This article describes our initial clinical experience with time-resolved MR angiography (MRA) of the legs using the time-resolved imaging with stochastic trajectories (TWIST) technique with a half dose of @entity2287 . MATERIALS AND METHODS: Thirty-four @entity1 underwent a TWIST examination of the legs at 3 T. Thirty-three @entity1 also underwent a bolus-chase MRA examination in the same setting. Times elapsed between the start of contrast injection and the appearance of contrast material (t(A)) and peak enhancement of the arteries in the legs (t(B)) were analyzed. The number of @entity1 with examinations affected by venous contamination was determined. The differences in t(A) and t(B) between cases in which venous contamination was present or absent were evaluated using a two-tailed Student t test. RESULTS: The TWIST technique using a half dose of @entity2287 provided diagnostic-quality images of all @entity1 . The mean t(A) was 35.5    8.8 (SD) seconds (range, 17.8-60.4 seconds), and the mean t(B) was 59.1    15.1 seconds (range, 31-98.8 seconds). Venous contamination was observed in bolus-chase MRA images of 52.9% of @entity1 . The relationship between venous contamination and t(A) was not statistically significant (p = 0.13). The incidence of venous contamination was higher in @entity1 with lower values of t(B) (p = 0.01). CONCLUSION: The described low-dose clinical experience with TWIST and the contrast dynamics information gained from this study could aid radiologists in planning protocols for leg MRA examinations.

Time-resolved MR angiography of the legs at 3 T using a low dose of XXXX : initial experience and contrast dynamics.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium']
@entity2287 :: (MESH:D005682,Chemical) :: ['gadolinium']
