BACKGROUND: Alcoholism is a health problem not only in developed countries but also in developing countries. @entity82 due to @entity167 is a common cause of @entity204 among individuals abusing @entity167 . A better knowledge of the spectrum of @entity5881 , its clinical, biochemical and histopathological features could result in early detection and prevention of @entity5881 before it's catastrophic and life threatening effects. MATERIALS AND METHODS: A total of 200 @entity1 with @entity5881 were studied with respect to @entity167 consumption, clinical features, biochemical and histopathological changes. The clinical features, biochemical parameters, and histopathology of liver including Ishak's modified @entity15803 ( @entity15803 ) were correlated with the amount and duration of @entity167 consumed. RESULT: Majority of the @entity1 were in the age group of 40-49 years and all the cases were males. Majority consumed @entity167 of about 75-90 grams per day for a duration of 10-12 years. @entity448 and @entity1087 were the most common symptom and clinical finding respectively. @entity3638 and @entity4988 were the most common abnormalities observed in liver function tests. Advanced @entity15803 stages with features of @entity82 were most frequent histo-pathological finding noted in this study. Clinico-biochemical profile was significantly correlated with degree of @entity167 ingestion as well as with liver histopathology. CONCLUSION: The wide prevalence of @entity5881 including @entity82 among Indian males was noted with significantly lower quantity and duration of @entity167 ingestion. The severity of @entity409 is directly proportional to the quantity and duration of @entity167 consumed. Clinical features and biochemical changes may forecast the liver histopathology among the @entity1 of @entity5881 .

Clinico-biochemical correlation to histological findings in XXXX : a single centre study from eastern India.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis', 'Cirrhosis'] @entity5881 :: ('MESH:D008108', 'Disease') :: ['alcoholic liver diseases', 'alcoholic liver disease'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity4988 :: ('MESH:D034141', 'Disease') :: ['hypoalbuminemia'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity15803 :: ('MESH:D009370', 'Disease') :: ['HAI', 'histological activity index'] @entity448 :: ('MESH:D000855', 'Disease') :: ['Anorexia'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver damage'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity3638 :: ('MESH:D006932', 'Disease') :: ['Hyperbilirubinemia']
@entity5881 :: (MESH:D008108,Disease) :: ['alcoholic liver disease']
