OBJECTIVE: To compare the results of femtosecond-assisted laser in situ keratomileusis (femto-LASIK) and photorefractive keratectomy with @entity1138 (PRK- @entity1139 ) for the correction of @entity1714 more than 7.0 diopters (D). METHODS: In this comparative nonrandomized trial, 60 eyes (30 eyes in each group) were enrolled. @entity1 were tested for uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent, ocular and corneal aberrations, and contrast sensitivity (CS) before surgery and at 3 and 6 months postoperatively. RESULTS: Mean preoperative @entity1714 was -8.65  1.51 and -8.04  1.70 D in the femto-LASIK and PRK- @entity1139 groups, respectively (P=0.149). Intergroup differences in baseline indices were not statistically significant. At 6 months after surgery, UDVA showed an improving trend, but it was better in the femto-LASIK group (P=0.026). CDVA in the two groups remained similarly unchanged (P=0.170). For the femto-LASIK and PRK- @entity1139 groups, the safety indices were 1.01  0.05 and 1.01  0.14 (P=0.949), respectively, and the efficacy indices were 0.99  0.07 and 0.93  0.22 (P=0.192), respectively. Comparing CS, only CS18 showed a significantly greater decrease in the femto-LASIK group compared with the PRK- @entity1139 group (P=0.016). Intergroup differences were not statistically significant in other spatial frequencies. Changes in the ocular and corneal higher order aberrations were not statistically different between the two groups except @entity772 , which increased in the femto-LASIK group (P=0.041). CONCLUSION: Femto-LASIK improves UDVA better than PRK- @entity1139 in high @entity1714 . However, because of increased @entity772 , the quality of vision is reduced. In other words, visual acuity outcome is better with femto-LASIK and visual quality outcome is better with PRK- @entity1139 .

Femtosecond-Assisted LASIK Versus PRK: Comparison of 6-Month Visual Acuity and Quality Outcome for XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin C'] @entity772 :: ('MESH:D003128', 'Disease') :: ['coma', 'ocular coma'] @entity1139 :: ('CHEBI:27504', 'Chemical') :: ['MMC'] @entity1714 :: ('MESH:D009216', 'Disease') :: ['myopia']
@entity1714 :: (MESH:D009216,Disease) :: ['High Myopia']
