We characterized the clinico-neurophysiological features of @entity302 , particularly focusing on high-voltage slow waves during ictal EEG. We studied 22 @entity1 with @entity302 recorded during digital video-scalp EEG, including five individuals who still had persistent @entity2473 after callosotomy. We analysed the duration, amplitude, latency to onset of electromyographic bursts, and distribution of the highest positive and negative peaks of slow waves in 352 @entity2473 . High-voltage positive slow waves preceded the identifiable muscle contractions of @entity2473 . The mean duration of these positive waves was 569  228  m, and the mean latency to electromyographic onset was 182  127  m. These parameters varied markedly even within a @entity1 . The highest peak of the positive component was distributed in variable regions, which was not consistent with the location of lesions on MRI. The peak of the negative component following the positivity was distributed in the neighbouring or opposite areas of the positive peak distribution. No changes were evident in the pre- or post-surgical distributions of the positive peak, or in the interhemispheric delay between both hemispheres, in individuals with callosotomy. Our data imply that ictal positive slow waves are the most common EEG changes during @entity2473 associated with a massive motor component. Plausible explanations for these widespread positive slow waves include the notion that EEG changes possibly reflect involvement of both cortical and subcortical structures.

Characterization of ictal slow waves in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2473 :: ('MESH:D013035', 'Disease') :: ['spasms'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epileptic spasms']
@entity302 :: (MESH:D004827,Disease) :: ['epileptic spasms']
