BACKGROUND: Skills such as empathy and emotion recognition rely on a multi-dimensional socio-emotional system. Increasingly, evidence suggests that socio-emotional cognition is affected in @entity4943 and @entity195 ( @entity195 ), to varying degrees. However, the specific dimensions of socio-emotional behavior and their neuroanatomical correlates have been relatively unexplored. OBJECTIVE: The current study aimed to: (i) determine how different dimensions of socio-emotional cognition are affected in @entity146 ( @entity146 ), @entity4943 ( @entity4943 ), and @entity195 ; (ii) investigate insight into socio-emotional cognition; (iii) identify the neural correlates subserving dimensions of socio-emotional cognition. METHODS: Sixteen @entity146 , 15 @entity4943 , 10 @entity195 @entity1 , and 17 controls were included. Each @entity1 and a nominated 'informant' completed the socio-emotional questionnaire; a 30-item rating scale assessing five dimensions of socio-emotional cognition (empathy, emotion recognition, social conformity, @entity146 , sociability). RESULTS: @entity4943 and @entity146 @entity1 were rated lower on measures of empathy and emotion recognition compared to @entity195 @entity1 and Controls, while other dimensions were relatively intact. In contrast, @entity1 with @entity195 were rated similarly to Controls across all dimensions. @entity4943 and @entity146 groups demonstrated reduced insight into @entity409 . Grey matter intensity in the temporal regions correlated with empathy and emotion recognition. Social conformity was associated with the orbitofrontal cortex and amygdala. CONCLUSION: Distinct profiles in typically presenting @entity146 , @entity4943 , and @entity195 illustrate preliminary evidence of the utility of socio-emotional cognition in diagnostic clarification. This is an important starting point in understanding socio-emotional functioning in younger-onset @entity303 , paving the way for targeted management and interventions.

Why Should I Care? Dimensions of  Socio-Emotional Cognition in  Younger-Onset XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'participant'] @entity146 :: ('MESH:D001523', 'Disease') :: ['antisocial behavior', 'bvFTD', 'behavioral-variant frontotemporal dementia'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity409 :: ('MESH:D008107', 'Disease') :: ['socio-emotional dysfunction'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"] @entity4943 :: ('MESH:D057180', 'Disease') :: ['frontotemporal dementia', 'SD', 'semantic dementia']
@entity303 :: (MESH:D003704,Disease) :: ['Dementia']
