BACKGROUND: @entity3124 following heart transplantation can include @entity810 ( @entity810 ). Study objectives were to define the epidemiology of, risk factors for, or impact on outcomes of @entity810 after pediatric heart transplant. METHODS: Using data from a prospective study of 66 young @entity1 , we evaluated: (1) post-operative @entity810 rate (by pediatric modified RIFLE criteria); (2) pre, intra, and early post-operative @entity810 risk factors using stepwise logistic regression (3) effect of @entity810 on short-term outcomes (ventilation and length of pediatric intensive care unit (PICU) stay) using stepwise multiple regression. RESULTS: @entity810 occurred in 73  % of @entity1 . Pre-transplant ventilation and higher baseline estimated @entity1011 clearance (eCCl) were independent risk factors for @entity810 . Pre-operative inotrope use was associated with reduced risk of @entity810 . @entity1140 level emerged as important in multivariable risk prediction. @entity1 with @entity810 had a longer duration of ventilation and length of pediatric intensive care unit (PICU) stay, with @entity810 being an independent predictor. CONCLUSIONS: @entity810 was common after heart transplant and associated with more complicated early post-transplant course. Lower baseline eCCl was associated with lower incidence of @entity810 ; this merits further investigation. The association of pre-operative inotropes with less @entity810 may reflect a pathophysiological mechanism or be a surrogate for clinical factors and management prior to transplant.  Avoiding high @entity1140 levels may be a modifiable risk factor for @entity810 .

Acute kidney injury after heart transplant in young XXXX : risk factors and outcomes.

@entity1 :: ('9606', 'Species') :: ['children', 'Children'] @entity3124 :: ('MESH:D016638', 'Disease') :: ['Critical illness'] @entity810 :: ('MESH:D058186', 'Disease') :: ['AKI', 'acute kidney injury'] @entity1140 :: ('MESH:D016559', 'Chemical') :: ['Tacrolimus', 'tacrolimus'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity1 :: (9606,Species) :: ['children']
