UNASSIGNED: We prospectively examined the relation of @entity3656 ( @entity3656 ), a marker of biological aging, to phobic @entity148 in later-life. @entity3656 in peripheral blood leukocytes were measured among 3194 @entity1 in the Nurses' Health Study who provided blood samples in 1989/90. The Crown-Crisp Phobic Index (CCI, range=0-16) was assessed in 1988 and 2004. Only @entity1 with CCI <=3 (consistent with no meaningful @entity148 ) in 1988 were included. We related baseline @entity3656 to odds ratios (ORs) of incident high @entity148 (CCI>= 6). To enhance clinical relevance, we used finite mixture modeling (FMM) to relate baseline @entity3656 to latent classes of CCI in 2004. @entity3656 were not significantly associated with high @entity148 after 16 years of follow-up. However, FMM identified 3 groups of phobic symptoms in later-life: severe, minimal/intermediate, and non-anxious. The severe group had non-significantly shorter multivariable-adjusted mean @entity3656 than the minimal/intermediate and non-anxious groups. @entity1 with shorter telomeres vs. longest telomeres had non-significantly higher likelihood of being in the severe vs. non-anxious group. Overall, there was no significant association between @entity3656 and incident @entity148 . Further work is required to explore potential connections of telomere length and emergence of severe @entity148 during later-life.

A prospective study of leukocyte telomere length and risk of phobic XXXX among @entity1 .

@entity3656 :: ('MESH:D007870', 'Disease') :: ['relative telomere lengths', 'RTLs'] @entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Women'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety symptoms', 'phobic anxiety symptoms', 'anxiety']
@entity148 :: (MESH:D001008,Disease) :: ['anxiety']
