A 66-year-old @entity1 developed paresthesia of the distal parts of the bilateral lower limbs a week after his upper @entity1729 , followed by the weakness with the legs and paresthesia with the lip area, tongue and finger tips. Those symptoms gradually became worse to the point that he was unable to walk 10 days later. Although @entity2118 , @entity4 , and lymph node swelling were not found, we made a diagnosis of @entity7555 ( @entity7555 ) because of clinical features of @entity305 , @entity12587 , @entity854 , elevated plasma level of @entity7 ( @entity7 ) and @entity8709 in his abdomen. Following intravenous immunoglobulin therapy (IVIg), he showed marked improvement. However, his neurologic symptoms deteriorated acutely just after open biopsy together with the elevation of @entity7 level, and a few days later he was in the state of flaccid @entity1688 . We tried IVIg therapy again and his neurologic symptoms were markedly improved. We speculated that an elevated @entity7 , released from plasma cells induced by the bioprocedure, might have caused an increase in microvascular permeability and affected the blood-nerve-barrier, thereby his neurologic symptoms deteriorated. It is thought that this case may support the hypothesis that a significant role is played by @entity7 in the pathomechanism of the development of @entity7555 . Additionally we experienced that IVIg was very effective to the neurologic symptoms, and we think that IVIg will be able to be one of the future therapy of the @entity7555 . To our knowledge, there has been no report of @entity7555 which manifested acute deterioration of his neurologic symptoms just after open biopsy with acute onset with @entity5011 like symptoms.

[A case of XXXX with @entity8709 : marked clinical deterioration following a biopsy to plasmacytoma].

@entity1 :: ('9606', 'Species') :: ['man'] @entity1688 :: ('MESH:D011782', 'Disease') :: ['quadriparesis'] @entity12587 :: ('MESH:D017099', 'Disease') :: ['IgG-lambda type M proteinemia'] @entity7 :: ('7422', 'Gene') :: ['vascular endothelial growth factor', 'VEGF'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity305 :: ('MESH:D011115', 'Disease') :: ['polyneuropathy'] @entity854 :: ('MESH:D018376', 'Disease') :: ['endocrinological abnormality'] @entity7555 :: ('MESH:D016878', 'Disease') :: ['Crow-Fukase syndrome', 'CFS'] @entity2118 :: ('MESH:D010859', 'Disease') :: ['skin pigmentation'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['respiratory infection'] @entity5011 :: ('MESH:D020275', 'Disease') :: ['Guillain-Barr   syndrome'] @entity8709 :: ('MESH:C537514', 'Disease') :: ['extramedullary plasmacytoma']
@entity7555 :: (MESH:D016878,Disease) :: ['Crow-Fukase syndrome']
