OBJECTIVE: To summarize the experiences of using continuous renal replacement therapy in the treatment of @entity209 caused by acute @entity63 . METHODS: Retrospective study of @entity1 diagnosed acute @entity63 with surgical treatment between January 2008 and December 2013, among which 22 @entity1 with @entity209 received continuous renal replacement therapy. Summarize the change tendency of @entity5632 , urine volume and serum creatinine levels during treatment and analysis the condition changes and prognosis of the @entity1 . RESULTS: Among them, 2 @entity1 were amputated and two died after surgery. The major causes of @entity204 were @entity810 , @entity520 , circulation failure and @entity1578 , etc. @entity5632 was significantly higher at Day 1 after surgery than that was before surgery (P < 0.05). Urine volume was significantly lower at Day 1 after surgery than that on the day of surgery (P < 0.05). CK was significantly lower at Day 2 after surgery than the day before (P < 0.05). Hemoglobin was significantly lower at Day 1 after surgery than that before surgery (P < 0.05). Serum creatinine levels remained steady. CONCLUSION: In @entity1 of acute @entity63 with @entity209 , early targeted continuous renal replacement therapy may decrease the serum concentrations of @entity5632 and CK, improve urine volume, maintain homeostasis, prevent @entity177 and improve the prognosis of @entity1 . And it is highly recommended.

[Application of continuous renal replacement therapy in the treatment of @entity209 caused by acute lower extremity XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity63 :: ('MESH:D007511', 'Disease') :: ['lower limb ischemia'] @entity5632 :: ('4151', 'Gene') :: ['Myoglobin', 'myoglobin'] @entity520 :: ('MESH:D000138', 'Disease') :: ['metabolic acidosis'] @entity1578 :: ('MESH:D017093', 'Disease') :: ['liver failure'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal function deterioration'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute renal failure'] @entity209 :: ('MESH:D008659', 'Disease') :: ['myonephropathic metabolic syndrome'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity63 :: (MESH:D007511,Disease) :: ['ischemia']
