Clinical and pathologic data from 51 @entity1 with primary @entity242 of the gastrointestinal tract treated from 1951 through 1984 were reviewed to determine clinical presentation, histologic features, treatment, and prognostic factors. The most common signs and symptoms were @entity490 (62%), @entity360 (40%), and/or abdominal mass (38%). The primary site was stomach in 50%, small bowel in 30%, colorectum in 15%, and esophagus in 5%. Virtually all the @entity242 were @entity1822 . Distribution was uniform among the three histologic grades; although 88% of Grade 1 @entity5 could be completely excised, only 35% of Grade 3 @entity5 could be completely resected. The 5-year survival rate was 75% for Grade 1 @entity5 , 16% for Grade 2 @entity5 , and 28% for Grade 3 @entity5 (p = 0.0013, Grade 1 vs. 2 and 3). Thirty of the 51 @entity1 (59%) had curative resection with an operative morbidity rate of 24% and an operative mortality rate of 12%; at 5 years the disease-free survival rate was 58% and the overall survival rate was 63% (48% at 10 years). Eleven @entity1 (42%) had recurrent disease develop at a median interval of 2 years after complete @entity5 excision. Twenty-one @entity1 (41%) had partial excision or biopsy only of their @entity5 with an operative morbidity rate of 28%, operative mortality rate of 8%, and median survival of only 9 months. Overall, @entity1 whose @entity5 were confined to the site of origin had a 58% 5-year survival rate compared with 20% for those whose @entity5 had invaded adjacent organs (p less than 0.05). If the @entity5 was less than 10 cm in size, the 5-year survival rate was 78%, significantly better than the 38% for @entity5 greater than 10 cm (p = 0.03). These data suggest that histologic grade, local invasiveness, size, and extent of resection are the most important prognostic factors for @entity1 with primary @entity344 . @entity1 who have resection of all gross @entity5 , especially if it is well differentiated and localized, have a good prognosis.

XXXX . Analysis of prognostic factors.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal sarcomas'] @entity1822 :: ('MESH:D007890', 'Disease') :: ['leiomyosarcomas'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity360 :: ('MESH:D006471', 'Disease') :: ['gastrointestinal bleeding']
@entity344 :: (MESH:D005767,Disease) :: ['Gastrointestinal sarcomas']
