UNASSIGNED: @entity1 value rewards less when these are delivered in the future as opposed to immediately, a phenomenon referred to as delay discounting. While delay discounting has been studied during the anticipation of rewards and in the context of intertemporal decision-making, little is known about its neural correlates in the outcome phase (during reward delivery) and their relation to @entity1314 . Personality traits that have been associated with increased delay discounting include @entity23 and, potentially, @entity308 . Here we performed functional magnetic resonance imaging (fMRI) in 72 healthy @entity1 while they carried out a @entity245 ( @entity245 ) task with a delay manipulation. In sixty percent of the experimental trials, @entity1 won rewards that differed in magnitude (0.05   , 0.50    or 1   ) and delay until delivery (immediately, 10 days, or 100 days). A factor analysis on questionnaires yielded two factors reflecting Impulsivity and @entity308 , which we used to examine potential relationships between @entity1314 and delay discounting. When winning a reward, medial prefrontal cortex (mPFC) activation was higher for immediate compared to delayed rewards. Moreover, amygdala activation correlated with reward magnitude for immediate but not for delayed rewards. Amygdala activation to winning immediate rewards was higher in more impulsive @entity1 , while mPFC activation to winning immediate rewards was higher in more anxious-depressed @entity1 . Our results uncover neural correlates of delay discounting during reward delivery, and suggest that @entity23 and subclinical @entity308 are related to stronger neural responses for winning immediate relative to delayed rewards.

XXXX without decision-making: medial prefrontal cortex and amygdala activations reflect immediacy processing and correlate with @entity23 and @entity308 .

@entity1 :: ('9606', 'Species') :: ['participants', 'Humans'] @entity308 :: ('MESH:D003866', 'Disease') :: ['anxious-depressive traits', 'Anxiety/Depression'] @entity245 :: ('MESH:D002658', 'Disease') :: ['MID', 'monetary incentive delay'] @entity23 :: ('MESH:D007174', 'Disease') :: ['impulsivity'] @entity1314 :: ('MESH:D010554', 'Disease') :: ['personality']
@entity245 :: (MESH:D002658,Disease) :: ['Delay discounting']
