OBJECTIVE: To evaluate the incidence, outcome and predictive value of cytology showing @entity2785 . @entity1 : Fifty-seven @entity1 with a smear diagnosis of @entity2785 registered between January 1997 and December 2001. SETTING: Colposcopy and cytopathology units in a large district general hospital. RESULTS: Sixty smears in 57 @entity1 showing @entity2785 were identified from a cohort of 135,120 smears, giving an incidence of 0.05%. Hospital records were available for 50 @entity1 . Final diagnosis included 13 cases of cervical @entity5436 (CGIN), 4 microinvasive cervical @entity420 , 2 undifferentiated @entity5 , 1 microinvasive @entity957 , 21 cases of @entity8046 and 13 cases of endometrial pathology (8 @entity1204 ). Twelve @entity1 had coexistent @entity1544 . Forty-five out of 50 @entity1 had significant pathology (positive predictive value 90%). Colposcopy was seen to be of limited value in assessment of smears showing @entity2785 . Only 1 out of 13 glandular lesions was diagnosed by colposcopy. CONCLUSION: Smears showing @entity2785 are associated with significant pathology in 90% of cases and @entity5 in 32% of cases. Hence, @entity1 with a @entity8544 should be referred urgently to a colposcopy clinic and flagged up as suspected @entity5 . @entity2785 should be included in the national referral criteria for suspected gynaecological @entity5 .

How significant is a cervical XXXX ?

@entity1 :: ('9606', 'Species') :: ['women', 'PARTICIPANTS'] @entity1204 :: ('MESH:D016889', 'Disease') :: ['endometrial cancers'] @entity2785 :: ('MESH:D009375', 'Disease') :: ['Glandular dyskaryosis', 'glandular dyskaryosis'] @entity8046 :: ('57026', 'Gene') :: ['CIN'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'tumours', 'malignancy'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous carcinoma'] @entity1544 :: ('MESH:D018307', 'Disease') :: ['squamous and glandular disease'] @entity8544 :: ('MESH:D005254', 'Disease') :: ['smear showing glandular dyskaryosis'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas'] @entity5436 :: ('MESH:D019048', 'Disease') :: ['glandular intraepithelial neoplasia']
@entity8544 :: (MESH:D005254,Disease) :: ['smear showing glandular dyskaryosis']
