OBJECTIVE: To explore the relationship between minimal disease activity (MDA) and the @entity258 activity cutoffs of the @entity5144 Activity Score (PASDAS) and the Composite Psoriatic Disease Activity Index (CPDAI). METHODS: Data from the GRAPPA (Group for Research and Assessment of Psoriasis and @entity5144 ) composite exercise (GRACE) study were used for these analyses. Alternative definitions of @entity258 activity were used with 6/7 and 7/7 of MDA items, and a criteria set mandating the 2 articular items and 3/5 alternate items ( @entity2720 ). Two reference questions were used as anchors: physician's global opinion of MDA, and @entity1 's opinion on their disease control. RESULTS: Substantial agreement was found between MDA, @entity2720 , PASDAS, and CPDAI. Compared to the 2 reference questions, the various definitions of @entity258 activity gave sensitivities that were generally worse than specificities, the latter being high (> 0.9) in most cases. Both PASDAS and CPDAI demonstrated good discrimination between the "low" and "high" disease activity states by all the MDA definitions. Using these data, with an MDA of 7/7 to define a very @entity258 cutoff, the corresponding values for PASDAS and CPDAI were 1.9 and 2, respectively. CONCLUSION: An MDA score of 7/7 is proposed as very @entity258 activity in @entity5144 . Using this definition, the equivalent cutoffs for PASDAS and CPDAI are 1.9 and 2, respectively.

Defining Low Disease Activity States in XXXX using Novel Composite Disease Instruments.

@entity2720 :: ('MESH:D007592', 'Disease') :: ['MDA-joints'] @entity1 :: ('9606', 'Species') :: ['patient'] @entity258 :: ('MESH:D009800', 'Disease') :: ['low disease'] @entity5144 :: ('MESH:D015535', 'Disease') :: ['Psoriatic ArthritiS Disease', 'psoriatic arthritis', 'Psoriatic Arthritis']
@entity5144 :: (MESH:D015535,Disease) :: ['Psoriatic Arthritis']
