OBJECTIVE: This study was undertaken to determine the safety, efficacy, and performance of @entity2636 -covered Wallstents in the treatment of @entity5 . SUBJECTS AND METHODS: This pilot study included 30 @entity1 with @entity5 . Palliative decompression of the obstructed bile duct was attempted with a @entity2636 -covered Wallstent that is a prototype. @entity1 with @entity3885 were excluded. All stents were inserted percutaneously. Kaplan-Meier analysis was used to determine stent patency. RESULTS: Effective biliary decompression was achieved in all @entity1 initially. No acute stent-related complications occurred. The 30-day mortality rate was 20%. During follow-up, 11 stent occlusions occurred; therefore, the occlusion rate was 37%. The patency rates after 1, 3, 6, and 12 months were 96%, 69%, 47%, and 31%, respectively. Tumor growth through the stent covering that was proven both histologically and by biopsy observed in two @entity1 , causing @entity432 in one of them. Other reasons for @entity432 were @entity5 ingrowth (n = 1) and biopsy-proven granulation tissue inside the stent (n = 2). Otherwise, the reasons for @entity432 remained unclear. CONCLUSION: This prototype of a covered stent did not provide better results than did conventional uncovered stents in @entity1 with @entity5 . The covering did not effectively prevent @entity5 ingrowth in at least two @entity1 . The stent also seems prone to premature occlusion.

Treatment of @entity5 with XXXX -covered Wallstents.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'distal tumor', 'malignant biliary obstruction'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['hilar obstructions'] @entity432 :: ('MESH:D001157', 'Disease') :: ['stent occlusion'] @entity2636 :: ('MESH:D011140', 'Chemical') :: ['polyurethane']
@entity2636 :: (MESH:D011140,Chemical) :: ['polyurethane']
