HISTORY AND CLINICAL FINDINGS: A 26-year-old @entity1 had a prolonged @entity221 , 10 kg weight loss and generalized @entity3329 , first diagnosed as a @entity706 . On admission he was febrile and in a markedly reduced physical condition. Submandibular, angular, cubital and inguinal lymph nodes were slightly enlarged bilaterally. INVESTIGATIONS: Serology and blood cultures were negative. Sonography and computed tomography showed enlarged lymph nodes in the neck, mediastinum, axillae, retroperitoneum and mesentery. Biopsies of lymph nodes and bone marrow revealed changes characteristic of @entity12692 . TREATMENT AND COURSE: @entity229 was administered, 20 mg daily for 20 days, the dose gradually reduced over 4 months. The @entity221 ceased after 14 days and the @entity1 's working capacity was fully restored after 7 weeks. CONCLUSION: In a case of prolonged @entity221 of unknown cause @entity12692 should be included in the differential diagnosis. It at first consists of polyclonal lymphatic proliferation. But transformation to @entity706 and systemic @entity2826 have been described in the disease's generalized form.

[ @entity12692 --a rare cause of a febrile state with XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'man'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['lymphadenopathy'] @entity2826 :: ('MESH:D012514', 'Disease') :: ["Kaposi's sarcoma"] @entity706 :: ('MESH:D008223', 'Disease') :: ['malignant lymphoma'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['Prednisone'] @entity12692 :: ('MESH:D005871', 'Disease') :: ["Castleman's disease"] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever']
@entity3329 :: (MESH:D008206,Disease) :: ['lymphadenopathy']
