Measures of body weight and anthropometrics such as body mass index (BMI) are commonly used to assess nutritional status in clinical conditions including @entity5 . Extensive research has evaluated associations between body weight and prognosis in @entity43 @entity1 , yet little is known about the potential impact of body composition (fat mass (FM) and fat-free mass (FFM)) in these @entity1 . Thus, the purpose of this publication was to review the literature (using PubMed and EMBASE) evaluating the impact of body weight and particularly body composition on surgical complications, morbidity, chemotherapy dosing and @entity137 (as predictors of prognosis), and survival in @entity43 @entity1 . Body weight is rarely associated with @entity532 , but @entity28 predicts higher rates of @entity1211 and wound complications post-operatively in @entity43 @entity1 . Low levels of FM and FFM are superior predictors of length of hospital stay compared to measures of body weight alone, but the role of body composition on other surgical morbidities is unknown. @entity28 complicates chemotherapy dosing due to altered pharmacokinetics, imprecise dosing strategies, and wide variability in FM and FFM. Measurement of body composition has the potential to reduce @entity137 if the results are incorporated into chemotherapy dosing calculations. Some findings suggest that excess body weight adversely affects survival, while others find no such association. Limited studies indicate that FM is a better predictor of survival than body weight in @entity43 @entity1 , but the direction of this relationship has not been determined. In conclusion, body composition as an indicator of nutritional status is a better prognostic tool than body weight or BMI alone in @entity43 @entity1 .

Impact of Body Weight and Body Composition on XXXX Prognosis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian cancer'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity28 :: ('MESH:D009765', 'Disease') :: ['Obesity', 'obesity'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity532 :: ('MESH:D003925', 'Disease') :: ['intra-operative complications'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thromboembolism']
@entity43 :: (MESH:D010051,Disease) :: ['Ovarian Cancer']
