UNASSIGNED: @entity0 is the most common @entity5 in @entity1 worldwide. In this study, we correlated the serum level of major histocompatibility complex class I-related chain A (sMICA) with expression and presentation of @entity3223 receptors on NK cells among @entity1 with @entity0 . Peripheral blood (PB) samples were collected from 49 healthy and 49 @entity0 @entity1 before surgery and chemotherapy. The expression and presentation of @entity3223 were assessed using qRT-PCR and flow cytometry, respectively. Furthermore, sMICA levels were determined using ELISA. In flow cytometry, whole blood samples were stained with anti- @entity2940 / @entity3223 /CD3 and the obtained results were analyzed using WinMDI software. In addition, SPSS software was used for statistical analysis of data. Significantly higher levels sMICA were detected in the sera of the majority of @entity5 @entity1 in contrast to healthy volunteers (P   <   0.001). The expression and presentation of @entity3223 were significantly lower than those in healthy @entity1 , and with an inverse correlation to sMICA and positively correlated with @entity5 stage. Our study showed that sMICA may have an important role in diminishing the expression and presentation of @entity3223 in @entity0 @entity1 and proposes the notion that sMICA can be a target candidate for treatment of @entity0 .

Assessment of changes in expression and presentation of XXXX under influence of MICA serum factor in different stages of @entity0 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'persons'] @entity3223 :: ('22914', 'Gene') :: ['NKG2D receptor', 'NKG2D'] @entity0 :: ('MESH:D001943', 'Disease') :: ['Breast cancer', 'breast cancer'] @entity2940 :: ('4684', 'Gene') :: ['CD56'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer']
@entity3223 :: (22914,Gene) :: ['NKG2D']
