PURPOSE: To report the cytologic characteristics of @entity2184 . DESIGN: This is a prospective, single-center study of consecutive @entity1 . SUBJECTS: All @entity1 with a clinical diagnosis of @entity2184 from May 2009 to July 2013 who underwent prognostication @entity400 ( @entity400 ) were included. METHODS: The cytologic characteristics of @entity2184 were analyzed for 150 consecutive @entity1 with a clinical diagnosis of @entity2184 who were treated at the Cleveland Clinic Cole Eye Institute between May 2009 and August  2012. MAIN OUTCOME MEASURES: Cellular features of all cases were analyzed for cell type, presence of melanin, nuclear grade, @entity5 -infiltrating lymphocytes, and @entity39 . Cytology was then correlated with histopathology in enucleated eyes. RESULTS: A total of 150 @entity1 were included. Seven samples of @entity5 resections were excluded from the study because they were studied by impression smears. A total of 143 @entity400 samples of 143 @entity1 formed the basis for analysis. Fifty-three percent of the @entity1 were male, and the average age for all @entity1 was 60 years. Transcorneal (n = 8), transscleral (n = 71), and transvitreal (n = 64) approaches were used. Of 143 samples, 131 were adequate. Among these, spindle cells were observed in 98% (63% mixed and 35% spindle only), whereas only epithelioid cells were observed in 2 samples. Melanin granules were observed in 80% of samples. Tumor nuclear grade (atypia) increased with @entity5 height and by @entity5 location (least atypia with @entity10633 ). CONCLUSIONS: Cytologic features such as spindle cells and melanin granules, present in 98% and 80% of samples, respectively, are important cytologic diagnostic features. Tumor nuclear grade (atypia) increased with @entity5 height. @entity320 has bland features compared with ciliary and @entity320 .

Diagnostic Cytologic Features of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity10633 :: ('MESH:D015811', 'Disease') :: ['iris tumors'] @entity2184 :: ('MESH:C536494', 'Disease') :: ['uveal melanoma'] @entity400 :: ('MESH:D014202', 'Disease') :: ['fine-needle aspiration biopsy', 'FNAB'] @entity320 :: ('MESH:D008545', 'Disease') :: ['Iris melanoma', 'choroidal melanoma']
@entity2184 :: (MESH:C536494,Disease) :: ['Uveal  Melanoma']
