OBJECTIVE: To evaluate the outcomes of intravenous glucocorticoid therapy with or without orbital radiotherapy for moderate-to-severe @entity6875 . METHODS: A total of 83 @entity1 with moderate-to-severe @entity6875 were retrospectively analyzed. Intravenous glucocorticoid was given to @entity1 for 3 consecutive days every four weeks in 1-3 circles. The regimens included intravenous glucocorticoid alone (n = 36) and intravenous glucocorticoid plus orbital radiotherapy (n = 47). Photophobia, lacrimation, @entity3856 , soft tissue congestion, @entity4 , @entity5768 and @entity892 were compared before and after treatment. The symptoms and efficacies were compared between two groups. RESULTS: During a 12-week follow-up, clinical activity score (CAS), @entity5768 and @entity892 all improved after treatment (P < 0.05). However, the changes of CAS, @entity5768 or @entity892 showed no inter-group differences (P > 0.05). The overall clinical response was 50% in glucocorticoid group and 63.8% in glucocorticoid plus orbital radiotherapy group. And there was no statistical difference (P > 0.05). CONCLUSION: Moderate-to-severe @entity6875 may be relieved by pulsed intravenous glucocorticoid with or without orbital radiotherapy. There is no inter-group difference in short-term efficacies.

[Short-term efficacies of intravenous glucocorticoid therapy for moderate-to-severe XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity5768 :: ('MESH:D005094', 'Disease') :: ['exophthalmos'] @entity892 :: ('MESH:D004172', 'Disease') :: ['diplopia'] @entity6875 :: ('MESH:D049970', 'Disease') :: ["Graves' ophthalmopathy"] @entity3856 :: ('MESH:D058447', 'Disease') :: ['eye pain']
@entity6875 :: (MESH:D049970,Disease) :: ['Graves' ophthalmopathy']
