BACKGROUND AND OBJECTIVE: Executive dysfunctions are a key clinical feature of behavioural-variant @entity4943 (bvFTD). @entity51 are also found in @entity195 ( @entity195 ), making the differentiation between these two diseases difficult at times, particularly in the absence of extensive cognitive assessments. To address this issue, we developed the FRONTIER Executive Screen (FES), which combines three abbreviated measures of verbal fluency, inhibitory control and working memory. METHODS: We administered the FES to 28 @entity1 with @entity303 (14 bvFTD, 14 @entity195 ) matched for disease severity and 33 age-matched and education-matched healthy controls. We also administered traditional tests of executive function to establish the concurrent validity of the FES. RESULTS: Both @entity1 groups obtained lower FES scores (total and subscores) compared to controls. Correct classification into @entity1 or control groups was reached in over 90% of study @entity1 based on the FES total score. Only two @entity1 with bvFTD obtained FES scores within 2 SDs of the control group. Receiver operating characteristic analyses on the @entity1 groups showed that a cut-off FES total score of 7/15 achieved 71% sensitivity and 73% specificity for a diagnosis of bvFTD. In addition, the FES showed high correlations with traditional measures of executive function. CONCLUSIONS: The FES is a brief (5-10   min) bedside screening measure which is simple to administer and score, and demonstrates good discriminative validity to differentiate bvFTD from @entity195 . It is a useful addendum to general cognitive screening measures and can help with the differential diagnosis of @entity303 .

FRONTIER Executive Screen: a brief executive battery to differentiate @entity4943 and XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'patient'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity51 :: ('MESH:D009461', 'Disease') :: ['Such deficits'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"] @entity4943 :: ('MESH:D057180', 'Disease') :: ['frontotemporal dementia']
@entity195 :: (MESH:D000544,Disease) :: ['Alzheimer's disease']
