OBJECTIVE: To investigate the clinical manifestations, pathological types, treatment and prognosis of primary @entity706 (PPL) and secondary @entity706 (SPL). METHODS: The clinical data of 40 cases of PPL or SPL diagnosed from 2003 to 2013 in the Chinese PLA General Hospital were retrospectively analyzed. All cases were diagnosed via lung biopsy or surgical biopsy. RESULTS: There were 24 male and 16 female @entity1 , aging from 15 to 84 years, including 10 @entity1 with PPL and 30 with SPL. The main clinical manifestations of PPL were cough and @entity662 , but 4 @entity1 were asymptomatic. Chest CT showed lung mass in 8 @entity1 and patchy opacities in 3.      F-FDG PET/CT showed that the SUV(max) of lung lesions was 3.96-6.70 with a median value of 4.50. The pathological types of all PPL cases were @entity1893 ( @entity1893 ), and 4 @entity1 were treated with surgery combined with chemotherapy, and 3 @entity1 were treated with surgery alone. The main clinical manifestations of SPL were cough, superficial lymph node enlargement and @entity221 , but 8 @entity1 were asymptomatic. The chest CT revealed @entity1143 in 20, mediastinal and hilar lymph node enlargement in 14, patch opacities in 13 and multiple nodules in 6 @entity1 . In addition to @entity358 , PET/CT examination confirmed that cervical lymph nodes, thyroid, stomach and pancreas were also involved. The SUV(max) was from 2.40 to 19.60, with a median value of 5.70. Twenty-one cases of SPL were @entity1893 and 9 were @entity978 ( @entity978 ). Of these @entity1 with SPL, 14 were treated with chemotherapy alone, 8 chemotherapy combined with radiotherapy, and 2 surgery combined with chemotherapy. The one-year survival rate of PPL was 100%, compared with 93.3% of SPL. The shortest survival time of PPL was 13 months, compared with 2 months of SPL. CONCLUSIONS: There were differences in the radiological features, pathological types and treatment between PPL and SPL. The chest CT manifestations of PPL were mainly lung masses, while those of SPL were mainly pleural involvement and mediastinal and hilar lymph node enlargement. The pathological type of PPL was all @entity1893 while that of 9 cases of SPL was @entity978 . @entity1 with PPL were mainly treated with surgical therapy, but SPL mainly with chemotherapy. PET/CT examination may be helpful for the diagnosis and staging of @entity706 . Since the misdiagnosis rate of @entity706 was high, diagnosis must rely on lung tissue biopsy and immunohistochemistry. Compared with PPL, the prognosis of SPL is poorer.

[A clinical analysis of 40 cases of primary and secondary XXXX ].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity1143 :: ('MESH:D010996', 'Disease') :: ['pleural effusions'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lung lymphoma', 'pulmonary lymphoma'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary involvement'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['NHL', 'non-Hodgkin lymphoma'] @entity978 :: ('MESH:D006689', 'Disease') :: ['HL', 'Hodgkin lymphomas'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever']
@entity706 :: (MESH:D008223,Disease) :: ['pulmonary lymphoma']
