BACKGROUND: @entity1109 result in poor quality of life and morbidity. AIMS: This study primarily examines key factors predicting and mitigating nocturnal symptom risks among @entity565 @entity1 , who were enrolled into a Singapore publicly funded @entity565 care programme. It also studies the association between nocturnal symptoms and medication changes as the secondary outcome. METHODS: A longitudinal study was conducted on 939 multi-racial Asian @entity1 with persistent @entity565 . @entity1 clinical and therapeutic data were retrieved retrospectively from the programme's database established in 2004. Association between nocturnal symptoms (defined as night-time cough, wheeze and @entity1353 at least twice monthly) and each categorical predictor was tested. The generalised linear mixed-effects model (GLIMM) was used to model the primary and secondary outcomes. RESULTS: Having @entity1109 was significantly associated with the number of days with @entity1353 , off usual activities and off work, and @entity565 severity at baseline (all P values <0.05). The @entity565 action plan (AAP) status is significantly associated with nocturnal symptoms after adjusting for race, age and smoking status at baseline (odds ratio (OR)=0.49 (updated @entity565 action plan versus none), OR=0.37 (been-on plan versus none)). The risks of @entity1109 increased over time for those with @entity2023 (OR=1.52) and reduced with subsequent visits (OR=0.91). Nocturnal symptoms increased the odds (OR=2.87) of switching from inhaled corticosteroid (ICS) to combination medications (ICS-LABA (long-acting b2-agonist)). CONCLUSIONS: The risks of having nocturnal symptoms were primarily associated with those with @entity2023 . An increase in @entity1 ' nocturnal symptoms was also predictive of the switching from ICS medications to combination formulations by their physicians.

Ten-year longitudinal study of factors influencing XXXX among Asian @entity1 in primary care.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity2023 :: ('MESH:D006255', 'Disease') :: ['allergic rhinitis'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['breathlessness'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['Nocturnal asthma symptoms', 'nocturnal asthma symptoms']
@entity1109 :: (MESH:D012678,Disease) :: ['nocturnal asthma symptoms']
