UNASSIGNED: Coronary CT angiography (CCTA) is used in @entity1 with low-intermediate @entity662 presenting to the emergency department for its reliability in excluding @entity1187 ( @entity1187 ). However, its influence on medication modification in this setting is unclear. We sought to determine whether knowledge of CCTA-based @entity453 ( @entity453 ) was associated with change in statin and @entity117 prescription. We used the CCTA arm of the Rule Out Myocardial Infarction using Computed Angiographic Tomography II multicenter, randomized control trial (R-II) and comparison cohort from the observational Rule Out Myocardial Infarction using Computed Angiographic Tomography I cohort (R-I). In R-II, subjects were randomly assigned to CCTA to guide decision making, whereas in R-I @entity1 underwent CCTA with results blinded to caregivers and managed according to standard care. Our final cohort consisted of 277 subjects from R-I and 370 from R-II. @entity1187 rate was similar (6.9% vs 6.2% respectively, p  = 0.75). For subjects with CCTA-detected obstructive @entity453 without @entity1187 , initiation of statin was significantly greater after disclosure of CCTA results (0% in R-I vs 20% in R-II, p  = 0.009). Conversely, for subjects without CCTA-detected @entity453 , @entity117 prescription was lower with disclosure of CCTA results (16% in R-I vs 4.8% in R-II, p  = 0.001). However, only 68% of subjects in R-II with obstructive @entity453 were discharged on statin and 65% on @entity117 . In conclusion, physician knowledge of CCTA results leads to improved alignment of @entity117 and statin with the presence and severity of @entity453 although still many @entity1 with CCTA-detected @entity453 are not discharged on @entity117 or statin. Our findings suggest opportunity for practice improvement when CCTA is performed in the emergency department.

Use of Coronary Computed Tomographic Angiography Findings to Modify Statin and @entity117 Prescription in @entity1 With Acute XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndrome'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'coronary artery disease']
@entity662 :: (MESH:D002637,Disease) :: ['Chest Pain']
