BACKGROUND: To report the effect of intraoperative electron beam radiotherapy (IOERT) and external beam radiotherapy (EBRT) in addition to surgery as well as to evaluate the role of resectable local recurrence for long-term prognosis. METHODS: In 53 @entity1 who underwent surgery for @entity242 ( @entity242 ) from 2001 to 2014 prognostic and epidemiologic factors were reviewed retrospectively to analyze their impact on survival and recurrence. RESULTS: Twenty three @entity1 (50%) had surgery plus radiotherapy, 23 (50%) had surgery only. Histology showed 73.9% @entity1821 , 15.2% @entity1822 and 6.5% pleomorphic @entity3491 respectively. @entity8597 were observed in 52.2%, high grade @entity242 in 47.8%. The latter showed a trend towards a decreased 5-year survival rate (p   =   0.125). Margin status was: R0: 60.9%, R1: 23.9%, R2: 15.2%; leading to significant changes in 5-year survival rate (R0: 77.6%; R1: 70.0%; R2: 42.9%; p   =   0.03). Age younger than 55  years significantly improved 5-year survival rate (p   =   0.039). @entity1 receiving resection of multiple @entity242 recurrence showed an almost identical improved 5-year survival rate compared to @entity1 without recurrence (no recurrence: 100.0%; single recurrence: 35.0%; multiple recurrence: 91.7%; p   =   0.001). Surgery plus radiotherapy led to significantly improved survival (p   =   0.04). CONCLUSIONS: There is a significant benefit in terms of 5-year survival after surgery plus some form of radiotherapy and a good prognosis for @entity1 when the recurrence from @entity242 was resected. Age older than 55  years and incomplete resection lowered 5-year survival rate significantly.

Significant benefits in survival by the use of surgery combined with radiotherapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity8597 :: ('MESH:D036821', 'Disease') :: ['Low grade sarcoma'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma', 'retroperitoneal soft tissue sarcoma', 'RSTS'] @entity3491 :: ('MESH:C580334', 'Disease') :: ['undifferentiated sarcoma'] @entity1822 :: ('MESH:D007890', 'Disease') :: ['leiomyosarcoma'] @entity1821 :: ('MESH:D008080', 'Disease') :: ['liposarcoma']
@entity242 :: (MESH:D012509,Disease) :: ['retroperitoneal soft tissue sarcoma']
