UNASSIGNED: The association of @entity560 status with @entity79 ( @entity79 ) and Quantitative Ultrasound measurements (QUS) has been inconsistent in previous studies, probably caused by moderating effects. This study explored (1) the association of @entity560 status with QUS and @entity79 , and (2) whether these associations were modified by body mass index (BMI), age, gender, or physical activity. Two-independent cohorts of the Longitudinal Aging Study Amsterdam (LASA-I, 1995/1996, aged >= 65; LASA-II, 2008/2009, aged 61-71) and baseline measurement of the B-vitamins for the prevention of @entity3604 (B-PROOF) study (2008-2011, aged 65+) were used. QUS measurements [broadband ultrasound attenuation (BUA) and speed of sound (SOS)] were performed at the calcaneus in all three cohorts (N  =  1,235, N  =  365, N  =  1319); @entity79 was measured by Dual X-ray absorptiometry (DXA) in B-PROOF (N  =  1,162 and 1,192 for specific sites) and LASA-I (N  =  492 and 503). The associations of @entity560 status with BUA and @entity79 were modified by BMI. Only in @entity1 with low-to-normal BMI (<25  kg/m(2)) and serum 25(OH)D <25  nmol/L was associated with lower BUA as compared to the reference group (>= 50  nmol/L) in LASA-I and B-PROOF. Furthermore, in LASA-I, these individuals had lower @entity79 at the hip and lumbar spine. In LASA-II, no associations with BUA were observed. @entity560 status was not associated with SOS, and these associations were not modified by the effect modifiers tested. The association between @entity560 status and BUA and @entity79 was modified by BMI in the older-aged cohorts: there was only an association in individuals with BMI <25  kg/m(2).

The Association Between XXXX Status and Parameters for Bone Density and Quality is Modified by Body Mass Index.

@entity3604 :: ('MESH:D058866', 'Disease') :: ['osteoporotic fractures'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity1 :: ('9606', 'Species') :: ['persons'] @entity560 :: ('MESH:D014807', 'Chemical') :: ['vitamin D', 'Vitamin D']
@entity560 :: (MESH:D014807,Chemical) :: ['Vitamin D']
