OBJECTIVE: Although it has been suggested that exposure to @entity281 during childhood could decrease risk of @entity65 ( @entity65 ), the evidence is scarce. We investigated the association of measles and mumps with @entity65 . METHODS: 43,689 @entity1 and 60,147 @entity1 aged 40-79 years at baseline (1988-1990) completed a lifestyle questionnaire, including their history of measles and mumps, and were followed until 2009. Histories of @entity281 were categorized as having no infection (reference), measles only, mumps only, or both @entity281 . Hazard ratios (HR) for mortality from @entity65 across histories of @entity281 were calculated. RESULTS: @entity1 with measles only had multivariable HR (95% confidence interval) of 0.92 (0.85-0.99) for total @entity65 , those with mumps only had 0.52 (0.28-0.94) for total @entity64 and 0.21 (0.05-0.86) for @entity64 , and those with both @entity281 had 0.80 (0.71-0.90) for total @entity65 , 0.71 (0.53-0.93) for @entity583 , and 0.83 (0.69-0.98) for total @entity64 . @entity1 with both @entity281 had 0.83 (0.74-0.92) for total @entity65 and 0.84 (0.71-0.99) for total @entity64 . We also compared subjects with measles only or mumps only (reference) and those with both @entity281 . @entity1 with both @entity281 had 0.88 (0.78-0.99) for total @entity65 . @entity1 with both @entity281 had 0.85 (0.76-0.94) for total @entity65 , 0.79 (0.67-0.93) for total @entity64 , 0.78 (0.62-0.98) for @entity385 and 0.78 (0.62-0.98) for @entity64 . CONCLUSIONS: Measles and mumps, especially in case of both @entity281 , were associated with lower risks of mortality from @entity65 .

Association of measles and mumps with XXXX : The  Japan Collaborative Cohort (JACC) study.

@entity1 :: ('9606', 'Species') :: ['women', 'Women', 'Men', 'men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'hemorrhagic stroke'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity65 :: ('MESH:D002318', 'Disease') :: ['atherosclerotic CVD', 'CVD', 'atherosclerotic cardiovascular disease'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular disease']
