BACKGROUND: Physical exercise may be valuable for @entity1 with @entity161 spectrum disorders as it may have beneficial effect on clinical symptoms, quality of life and cognition. METHODS: A systematic search was performed using PubMed (Medline), Embase, PsychInfo, and Cochrane Database of Systematic Reviews. Controlled and uncontrolled studies investigating the effect of any type of physical exercise interventions in @entity161 spectrum disorders were included. Outcome measures were clinical symptoms, quality of life, global functioning, @entity308 or cognition. Meta-analyses were performed using Comprehensive Meta-Analysis software. A random effects model was used to compute overall weighted effect sizes in Hedges' g. RESULTS: Twenty-nine studies were included, examining 1109 @entity1 . Exercise was superior to control conditions in improving total symptom severity (k = 14, n = 719: Hedges' g = .39, P < .001), positive (k = 15, n = 715: Hedges' g = .32, P < .01), negative (k = 18, n = 854: Hedges' g = .49, P < .001), and general (k = 10, n = 475: Hedges' g = .27, P < .05) symptoms, quality of life (k = 11, n = 770: Hedges' g = .55, P < .001), global functioning (k = 5, n = 342: Hedges' g = .32, P < .01), and @entity308 (k = 7, n = 337: Hedges' g = .71, P < .001). Yoga, specifically, improved the cognitive subdomain long-term memory (k = 2, n = 184: Hedges' g = .32, P < .05), while exercise in general or in any other form had no effect on cognition. CONCLUSION: Physical exercise is a robust add-on treatment for improving clinical symptoms, quality of life, global functioning, and @entity308 in @entity1 with @entity161 . The effect on cognition is not demonstrated, but may be present for yoga.

Exercise Improves Clinical Symptoms, Quality of Life, Global Functioning, and @entity308 in XXXX : A Systematic Review and Meta-analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression', 'depressive symptoms'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia']
@entity161 :: (MESH:D012559,Disease) :: ['Schizophrenia']
