Long-term survival following surgery for @entity356 limited to the subserosa was analyzed. Between 01.01.1984 and 30.06.1995. 265 @entity1 were operated for @entity356 that did not invade beyond the subserosa. Extended lymphadenectomy was performed in all cases and was constant as all @entity1 were operated by only two surgeons. The survival outcome was analyzed with particular regard to the exact depth of @entity5 infiltration and lymph node involvement. The percentage of @entity1 with positive lymph nodes increased drastically from 1.7% for mucosal invasion to 22.7% for submucosal @entity5 involvement. A further substantial increase was observed from 34.3% for involvement of the muscularis propria to 66.1% for subserosal involvement. The 10-year @entity5 specific survival rate for @entity5 limited to the mucosa was 100%, for submucosa and muscularis propria invasion 79.3% and 72.9% respectively, for subserosal involvement 10-year survival was 54.6%. In multivariate analysis of pathohistological variables only pT- and pN-categories according to the UICC were found to have independent prognostic influence on survival. Long-term survival indicates that @entity356 limited to the mucosa may well be treated with a less radical approach. @entity356 both have a similar good long-term prognosis with radical surgery alone whereas @entity5 of the subserosa probably requires some form of adjuvant therapy.

Long-term survival analysis of XXXX limited to the subserosa.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer', 'tumors'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'Gastric cancer of the submucosa and muscularis propria']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
