BACKGROUD: @entity5327 ( @entity5327 ) is an uncommon but catastrophic @entity455 with high rate of intestinal failure and mortality. The retrospective pilot study was performed to assess the effect of a multidisciplinary stepwise management strategy on survival and mesenteric recanalization in an integrated intestinal @entity64 center (ISC). MATERIALS AND METHODS: A modern management strategy performed by multidisciplinary specialists in ISC was evaluated among 43 @entity5327 @entity1 that were classified into central vs peripheral type, operative vs nonoperative, early vs late treated group from March 2009 to April 2013. @entity1 received specific medical therapy, endovascular treatment, damage-control surgery, selective second-look laparotomy, critical care management, and clinical nutrition support in a stepwise way. The demographics, etiology, imaging characteristics, treatment procedures, complications, clinical outcome, and 1-year follow-up data were analyzed and compared. Confounding factors of mortality were identified by univariate and ROC-curve analysis. A single-center experience of over 5years for this modern strategy was also reported. RESULTS: The protocol of multidisciplinary stepwise management strategy was followed in all @entity5327 @entity1 successfully. The 30-day mortality and recanalization rate were 11.63% and 90.70%. Initial damage-control surgery was carried out in 46.51% @entity1 , with selective second-look laparotomy in 23.26% @entity1 . Endovascular thrombolysis was performed in 83.72% @entity1 initially or postoperatively. Bowel resection was necessary in 18 @entity1 with the length of 100.00 (47.50, 222.50) cm. The incidence of @entity5277 was 13.95%. The rate and length of bowel resection, @entity5277 rate were significantly lower in nonoperative and early-treated groups (P<0.05). During the follow-up survey, 1-year survival was 83.72%, with no additional death or re- @entity715 . CONCLUSION: A multidisciplinary stepwise management strategy involving modern surgical and endovascular treatments that focus on early mesenteric recanalization and bowel viability salvage in a specialized ISC could significantly improve the clinical outcome of @entity5327 @entity1 .

Multidisciplinary stepwise management strategy for acute superior mesenteric venous thrombosis: an intestinal XXXX center experience.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity455 :: ('MESH:D014652', 'Disease') :: ['abdominal vascular emergency'] @entity5277 :: ('MESH:D012778', 'Disease') :: ['short-bowel syndrome'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity5327 :: ('MESH:D065666', 'Disease') :: ['Acute superior mesenteric venous thrombosis', 'ASMVT']
@entity64 :: (MESH:D020521,Disease) :: ['stroke']
