OBJECTIVE: The objectives of the management of @entity1412 are to eliminate or reduce the size of @entity1127 , reestablish nasal breathing, reduce symptoms of @entity2490 , restore the sense of smell, and prevent the recurrence of @entity480 . Local or systemic @entity230 have been used in the treatment of @entity480 , but efficacy of combined (local and systemic) @entity230 in @entity1412 has been little investigated. The aim of this study was to evaluate the influence of combined @entity134 therapy on the symptoms and extent of the disease in @entity1 with @entity1412 . METHODS: Seventeen @entity1 with @entity480 were treated with combined @entity230 . Before and after the therapy, polyp size, nasal symptoms, sense of smell, and @entity10 or facial @entity158 were assessed by an established scoring system. RESULTS: After the therapy, symptom scores of all the @entity1 improved. Of the @entity1 , 12% showed a polyp-free nasal cavity, 76% a clear involution of @entity1127 , and 12% no response to the therapy. There were statistically significant differences (P<0.001) for symptom scores and polyp size. Medical ablation of @entity1127 using @entity230 was not achieved in 88% @entity1 . CONCLUSION: @entity230 can reduce polyp sizes and improve the symptoms, but are inadequate to eradicate the @entity1127 . Surgery still plays a major part in the treatment of the @entity1412 , but @entity230 can delay the necessity for surgical intervention.

The effectiveness of XXXX treatment in @entity1412 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity2490 :: ('MESH:D012220', 'Disease') :: ['rhinitis'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['steroid'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['Steroids', 'steroids'] @entity1412 :: ('MESH:D011125', 'Disease') :: ['nasal polyposis'] @entity480 :: ('MESH:D009298', 'Disease') :: ['nasal polyps']
@entity134 :: (CHEBI:35341,Chemical) :: ['steroid']
