@entity99 ( @entity99 ) is a frequent @entity1575 that causes poor quality of life, a great burden to caregivers, and can be treated. For diagnosis and grading the international guidelines recommend the use of psychometric tests of different modalities (computer based vs. paper and pencil). To compare results of the Continuous Reaction time (CRT) and the @entity75 ( @entity75 ) tests in a large unselected cohort of @entity82 @entity1 without clinically detectable @entity75 and to clinically characterize the @entity1 according to their test results. The CRT method is a 10-minute computerized test of a @entity1 's motor reaction time stability (CRTindex) to 150 auditory stimuli. The @entity75 test is a 20-minute paper-pencil test evaluating psychomotor speed. Both tests were performed at the same occasion in 129 @entity1 . Both tests were normal in only 36% (n   =   46) of the @entity1 and this group had the best quality of life, a normal CRP, a low risk of subsequent overt HE, and a low short term mortality. Either the CRT or the @entity75 test was abnormal in a total of 64% of the @entity1 (n   =   83), the CRT in 53% (n   =   69) and the @entity75 in 34% (n   =   44). All these @entity1 had a poorer quality of life, low-grade CRP elevation, moderate risk for subsequent overt HE, and a higher than 20% short term mortality. Both tests were abnormal in 23% (n   =   30) of the @entity1 and this group had more advanced @entity82 and a 40 % short-term mortality. One of the tests was abnormal in the majority of the @entity1 but concordant in only 60%. Most @entity82 @entity1 seem to have impairments of different cognitive domains and more domains with advancing disease. Two abnormal tests identified @entity1 with an increased risk of overt HE and @entity204 .

XXXX characterized by parallel use of the continuous reaction time and portosystemic @entity75 tests.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['Portosystemic Encephalopathy', 'PSE', 'brain impairment'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['complication to liver cirrhosis'] @entity99 :: ('MESH:D056486', 'Disease') :: ['Minimal hepatic encephalopathy', 'MHE'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity99 :: (MESH:D056486,Disease) :: ['Minimal hepatic encephalopathy']
