To assess and validate the incorporation of the multiparametric magnetic resonance imaging (mpMRI) @entity5 category (mT-category) to the conventional clinical @entity5 category (cT-category), in order to guide the radiotherapy (RT) treatment decisions in @entity263 . In addition, to identify the clinical factors associated to the technique reliability. mpMRI was performed in 274 @entity263 @entity1 in order to refine the treatment decisions according to PSA, Gleason Score (GS) and cT-category. Comparisons between the cT and mT-category were performed, as well as the impact on the RT treatment [target volume, doses and hormonal therapy (HT)] independently if it was finally performed. Changes in HT indication for intermediate risk were also analyzed. mpMRI validation was performed with pathological staging (n  =  90 @entity1 finally decided to join surgery). The mpMRI upstaging range was 86-94  % for any PSA value or GS. Following mpMRI, 32.8  % of the @entity1 (90/274) were assigned to a different risk group. Compared to cT-category, mpMRI identified more intermediate-risk (46.4 vs. 59.5  %) and high-risk (19.0 vs. 28.8  %) @entity263 @entity1 . This resulted in a higher indication (p  <  0.05) of seminal vesicle irradiation (63.5 vs. 70.0  %), inclusion of any extracapsular disease ( @entity3214 ) within the target volume (1.8 vs. 18.2  %), higher doses (65.3 vs. 88.3  %) and HT associated to RT (45.6 vs. 62.4  %). Global accuracy for mpMRI was higher compared to DRE/TRUS (8.9 vs. 71.1  %, p  <  0.05). mpMRI reliability was independent of PSA or GS. mpMRI @entity5 staging significantly modified the RT treatment decisions in all @entity263 risk groups.

@entity5 staging using 3.0 T multiparametric MRI in XXXX : impact on treatment decisions for radical radiotherapy.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumour'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity3214 :: ('MESH:D005067', 'Disease') :: ['T3-T4'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
