A 61-year-old female with a past history of @entity356 presented with @entity1032 , a few @entity410 , and low-grade fever. Lumbar puncture revealed elevated cerebrospinal fluid (CSF) pressure, lymphocytic pleocytosis, elevated protein level, remarkably decreased @entity413 level, and presence of cryptococcal antigen. @entity1327 was identified by India ink staining and culture of CSF. The @entity1 was given antifungal agents intravenously and intrathecally. CSF findings improved and @entity1327 could not be detected in CSF one month after the onset. Cerebral sulcal hyperintensity was identified in the bilateral frontal and parietal lobes on fluid-attenuated inversion recovery (FLAIR) magnetic resonance (MR) imaging one month after the onset, but no leptomeningeal enhancement was detected in the affected sulci on T1-weighted MR imaging. The sulcal hyperintensity on FLAIR imaging developed in the bilateral temporal and occipital lobes 2 months after the onset. CSF findings obtained by lumbar puncture were within the normal range except for pressure. However, @entity16 and reconfirmation of @entity1327 in CSF indicated recurrent @entity32 . The sulcal hyperintensity on FLAIR imaging may indicate a high CSF protein concentration in the subarachnoid space. Such cerebral sulcal hyperintensity is an unusual MR imaging finding of cryptococcal @entity5422 , and may be an early sign of procrastinating process or recurrent inflammation even if the findings of CSF obtained by lumbar puncture are normal.

Cryptococcal XXXX presenting with an unusual magnetic resonance imaging appearance--case report.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['cryptococcal inflammation'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['altered mental status'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity5422 :: ('MESH:D008590', 'Disease') :: ['meningoencephalitis'] @entity1327 :: ('5207', 'Species') :: ['Cryptococcus neoformans', 'C. neoformans'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological deterioration'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity5422 :: (MESH:D008590,Disease) :: ['meningoencephalitis']
