INTRODUCTION: @entity2014 ( @entity2014 ) is a rare clinical syndrome caused by an enlarging, aggressive corticotroph pituitary @entity652 that can occur following bilateral adrenalectomy performed in the treatment of refractory @entity699 ( @entity699 ). @entity5 respond poorly to currently available therapeutic options, which include surgery, radiotherapy, pharmacotherapy, and chemotherapy. They are a challenging problem in neurosurgical practice. The aim of this work was to evaluate the early and long-term results of microsurgery in a single surgeon's series of @entity1 with @entity2014 . MATERIAL AND METHODS: During the period from January 2000 to December 2005, 10 @entity1 with @entity2014 underwent surgery. The authors analysed surgical outcomes in the @entity2014 group of seven @entity1 and three @entity1 with the mean age of 47.99 years (range 39-66, SD    8.47 years). @entity2014 was diagnosed based on clinical signs and symptoms, especially @entity2117 of the skin, elevated serum @entity4545 levels, and @entity5 growth. Parasellar extension of the @entity652 was assessed in both groups according to Knosp's and @entity2360 . Pituitary function and radiographs were evaluated in the early postoperative period, 30 days after the operation, and during follow-up. Histological examination was based on the WHO (2004) criteria. RESULTS: According to the criteria for @entity2014 remission, five @entity1 (50%) were cured. No perioperative mortality was reported. Three @entity1 developed @entity4614 and two @entity1 developed @entity2010 . There was one case of postoperative @entity5173 . One @entity1 was diagnosed with @entity977 . CONCLUSIONS: Transsphenoidal microsurgical removal of @entity977 is a safe and effective treatment of @entity2014 . (Endokrynol Pol 2015; 66 (6): 504-513).

Outcomes in pituitary surgery in XXXX - therapeutic pitfalls.

@entity1 :: ('9606', 'Species') :: ['men', 'patient', 'women', 'patients'] @entity4545 :: ('5443', 'Gene') :: ['ACTH'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Such tumours', 'pituitary tumour'] @entity2117 :: ('MESH:D017495', 'Disease') :: ['hyperpigmentation'] @entity699 :: ('MESH:D003480', 'Disease') :: ["Cushing's disease", 'CD'] @entity5173 :: ('MESH:D065634', 'Disease') :: ['cerebrospinal fluid leakage'] @entity4614 :: ('MESH:D007018', 'Disease') :: ['pituitary insufficiency'] @entity2360 :: ('MESH:D006527', 'Disease') :: ['Hardy-Wilson classifications'] @entity977 :: ('MESH:D010911', 'Disease') :: ['pituitary adenomas', 'pituitary carcinoma'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas', 'adenoma'] @entity2014 :: ('MESH:D009347', 'Disease') :: ['NS', "Nelson's syndrome", "Nelson' syndrome"] @entity2010 :: ('MESH:D003919', 'Disease') :: ['diabetes insipidus']
@entity2014 :: (MESH:D009347,Disease) :: ['Nelson's syndrome']
