CONTEXT: @entity2299 is frequently observed in @entity1 with a greater amount of @entity1386 ( @entity1386 ). However, it is still uncertain whether @entity1386 is independently associated with the future development of @entity2299 . OBJECTIVES: The aim of this study was to determine whether baseline and changes in @entity1386 and @entity1386 ( @entity1386 ) are associated with future development of @entity2299 independent of baseline lipid levels and standard anthropometric indices. DESIGN AND SETTING: Community-based prospective cohort study with 5 years of follow-up. @entity1 : A total of 452 Japanese Americans (240 @entity1 , 212 @entity1 ), aged 34-75 years were assessed at baseline and after 5 years of follow-up. MAIN OUTCOME MEASURES: Abdominal fat areas were measured by computed tomography. @entity2299 was defined as one or more abnormalities in high-density lipoprotein (HDL) @entity165 , @entity1674 , or non-HDL @entity165 levels. RESULTS: Baseline @entity1386 and change in @entity1386 over 5 years were independently associated with log-transformed HDL @entity165 , log-transformed @entity412 , and non-HDL @entity165 after 5 years (standardized b = -0.126, 0.277, and 0.066 for baseline @entity1386 , respectively, and -0.095, 0.223, and 0.090 for change in @entity1386 , respectively). However, baseline and change in @entity1386 were not associated with any future atherogenic lipid level. In multivariate logistic regression analysis, @entity1386 (odds ratio [95% confidence interval], 1.73 [1.20-2.48]; P = .003), @entity1674 (4.01 [1.72-9.33]; P = .001), HDL @entity165 (0.32 [0.18-0.58]; P < .001), and non-HDL @entity165 (7.58 [4.43-12.95]; P < .001) were significantly associated with the future development of @entity2299 independent of age, sex, diastolic blood pressure, homeostasis model assessment insulin resistance, body mass index (BMI), change in BMI, @entity1386 , and baseline atherogenic lipid levels. CONCLUSION: Baseline and change in @entity1386 were independent predictors for future development of @entity2299 . However, BMI, waist circumference, and @entity1386 were not associated with future development of @entity2299 .

Increased Visceral Adipose Tissue Is an Independent Predictor for Future Development of XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'PARTICIPANTS', 'persons', 'men'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['atherogenic dyslipidemia', 'Atherogenic dyslipidemia'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity1386 :: ('MESH:D018205', 'Disease') :: ['subcutaneous adipose tissue', 'visceral adipose tissue', 'incremental change in VAT', 'SAT', 'VAT'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity2299 :: (MESH:D050171,Disease) :: ['Atherogenic Dyslipidemia']
