OBJECTIVE: Free flap transfer is an essential part of limb-sparing surgery for leg @entity242 ; however, this procedure is associated with a high failure rate. The aim of this study was to identify factors that contribute to microvascular compromise and flap failure for leg free flap transfer, while focusing on anastomotic techniques (end-to-end, end-to-side, and flow-through anastomoses). @entity1 AND METHODS: Data from 56 consecutive @entity1 who underwent leg free flap transfer after oncologic resection were retrospectively reviewed. Of these @entity1 , flow-through @entity254 was performed with the artery in 29 and the vein in 24, whereas conventional techniques were performed in others. The variables contributing to microvascular compromise and flap failure were statistically analyzed. RESULTS: @entity49 (four @entity1 , 7.1%) was more frequent than @entity715 (one @entity1 , 1.8%) and (4 @entity1 , 7.1%) resulted in flap loss. All @entity177 occurred in end-to-end anastomoses. All flow-through anastomoses achieved patency both for the artery and vein. No anastomotic failure or flap loss occurred in 22 flaps which were transferred with flow-through @entity254 for both the artery and vein. Flow-through @entity1211 tended to have a lower rate of microvascular compromise and flap loss than conventional techniques (P = 0.13 and 0.25, respectively). CONCLUSION: The key to successful leg free flap transfer is to prevent @entity177 ; thus, flow-through @entity1211 may be a breakthrough solution. Preferential use of flow-through @entity254 for both the artery and vein can provide predictable results in leg free flap transfer.

Flow-through XXXX for both the artery and vein in leg free flap transfer.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity49 :: ('MESH:D019851', 'Disease') :: ['Venous thrombosis'] @entity177 :: ('MESH:D051437', 'Disease') :: ['venous failure', 'anastomotic failures'] @entity715 :: ('MESH:D013927', 'Disease') :: ['arterial thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous anastomosis']
@entity254 :: (MESH:C563598,Disease) :: ['anastomosis']
