OBJECTIVES/HYPOTHESIS: To evaluate the population characteristics of mucosal @entity320 and paranasal sinuses and determine the impact of the new staging classification. STUDY DESIGN: Analysis of a national database. METHODS: @entity1 were identified from the Surveillance, Epidemiology, and End Results @entity5 registry data with mucosal @entity320 and paranasal sinuses between 2000 and 2007. @entity5 were classified using the American Joint Committee on Cancer (AJCC) 6th edition site-specific staging as well as 7th edition staging for @entity135 ( @entity135 ). Incidence rates and descriptive statistics were calculated, and multivariate analysis was performed to examine the impact of demographic factors and staging on survival. RESULTS: A total of 304 @entity1 were identified. The incidence rate was 0.05 per 100,000. Fifty-six percent were female, 92% were >50 years old, and more than 90% were Caucasian; 81.6% of @entity1 were treated with surgery, and 38.5% of @entity1 received postoperative radiation. Overall, the 5-year survival rate was 24.2%. Significant differences in survival were observed for surgery with radiation (P = .005) and surgery alone (P = .04) compared with radiation alone. TNM staging using the AJCC 6th and 7th edition classification schemes yielded similar survival curves. However, the new classification for @entity135 allows for better delineation of stage IV disease, revealing slightly improved survival for stage @entity3480 . CONCLUSIONS: @entity135 is a rare disease with a poor prognosis. Surgery remains the treatment of choice, with some role for adjuvant therapy. The new staging classification for @entity135 appears to more efficiently stage this disease. Demographics and therapeutic findings are discussed.

Demographics and treatment trends in sinonasal XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck mucosal melanoma', 'HNMM'] @entity3480 :: ('MESH:C538167', 'Disease') :: ['IVA disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumors'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma of the nasal cavity']
@entity320 :: (MESH:D008545,Disease) :: ['mucosal melanoma']
