BACKGROUND: Earlier approaches to pallidotomy for @entity191 had significant complication rates. More recent approaches show fewer complications, but the effect of pallidotomy on cognition is unclear. The current study was conducted to examine the neuropsychological effects of unilateral pallidotomy. METHODS: Neuropsychological testing was performed on @entity1 with medically refractory, predominantly unilateral @entity191 at baseline and after unilateral ventral pallidotomy (n=28) or after an equivalent period without surgery in control @entity1 (n=10). RESULTS: Pallidotomy @entity1 showed no significant changes from baseline to retesting relative to the control group for any measure. Across all of the tests administered, only five of the surgery @entity1 showed a significant decline, and of these five none declined on more than one test. @entity308 did not relate to @entity73 . The pallidotomy group showed a significant improvement in motor functioning and activities of daily living whereas the control group did not. These measures were not associated with the neuropsychological test scores at baseline or retest. CONCLUSIONS: Stereotactic unilateral ventral pallidotomy does not seem to produce dramatic @entity73 in most @entity1 .

Cognitive functioning after pallidotomy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity73 :: ('MESH:D003072', 'Disease') :: ['preoperative or postoperative cognition', 'cognitive declines'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease", "refractory Parkinson's disease"]
@entity191 :: (MESH:D010300,Disease) :: ['refractory Parkinson's disease']
