BACKGROUND AND PURPOSE: MR fingerprinting allows rapid simultaneous quantification of T1 and T2 relaxation times. This study assessed the utility of MR fingerprinting in differentiating common types of adult intra-axial @entity1313 . MATERIALS AND METHODS: MR fingerprinting acquisition was performed in 31 @entity1 with @entity1313 : 17 @entity463 , 6 World Health Organization grade II lower grade @entity11 , and 8 @entity3 . T1, T2 of the solid @entity5 , immediate peritumoral white matter, and contralateral white matter were summarized within each ROI. Statistical comparisons on mean, SD, skewness, and kurtosis were performed by using the univariate Wilcoxon rank sum test across various @entity5 types. Bonferroni correction was used to correct for multiple-comparison testing. Multivariable logistic regression analysis was performed for discrimination between @entity463 and @entity3 , and area under the receiver operator curve was calculated. RESULTS: Mean T2 values could differentiate solid @entity5 regions of lower grade @entity11 from @entity3 (mean, 172    53 ms, and 105    27 ms, respectively; P = .004, significant after Bonferroni correction). The mean T1 of peritumoral white matter surrounding lower grade @entity11 differed from peritumoral white matter around @entity463 (mean, 1066    218 ms, and 1578    331 ms, respectively; P = .004, significant after Bonferroni correction). Logistic regression analysis revealed that the mean T2 of solid @entity5 offered the best separation between @entity463 and @entity3 with an area under the curve of 0.86 (95% CI, 0.69-1.00; P < .0001). CONCLUSIONS: MR fingerprinting allows rapid simultaneous T1 and T2 measurement in @entity1313 and surrounding tissues. MR fingerprinting-based relaxometry can identify quantitative differences between solid @entity5 regions of lower grade @entity11 and @entity3 and between peritumoral regions of @entity463 and lower grade @entity11 .

MR Fingerprinting of XXXX : Initial Experience.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['untreated intra-axial brain tumors', 'brain tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity11 :: ('MESH:D005910', 'Disease') :: ['gliomas'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity463 :: ('MESH:D005909', 'Disease') :: ['glioblastomas']
@entity1313 :: (MESH:D001932,Disease) :: ['Adult Brain Tumors']
