OBJECTIVE: This paper reports on a study designed to (i) assess levels of executive functions among @entity1 suffering from @entity161 ; (ii) investigate associations between measures of executive functions and psychosocial adjustment; and (iii) examine the influence of psychopathology on the relationship between executive functions and psychosocial adjustment. Clear knowledge of executive functions and of their impact on social adjustment in @entity1 with @entity161 may play a decisive role in preparing and structuring appropriate outpatient care. METHOD: An extensive battery constituted of several tests developed for the assessment of executive functions was used in 38 inpatients with a DSM-IV diagnosis of @entity161 . Psychosocial adjustment was assessed with a set of commonly used scales. RESULTS: Performance on measures of executive functions was heterogeneous among the @entity1 population, with a subgroup performing within normal scores. A similar pattern was found on measures of psychosocial adjustment. Most of the executive measures were not dependent on demographic or clinical variables. A factorial analysis on measures of psychosocial adjustment yielded a one-factor model which showed inconsistent, and at most, weak to moderate correlations with executive functions. Regression analysis revealed that symptom levels accounted for two-thirds of the variance of psychosocial adjustment, and together with measures of executive functions for 91% of the variance. General and negative symptoms showed strong correlations with psychosocial adjustment. CONCLUSIONS: Our study supports the view that executive function is a heterogeneous construct with several subdimensions. Additionally, it suggests that symptom level has an important role as "rate limiting factor" on psychosocial adjustment and is partially mediated by @entity409 . Our results call for careful and detailed assessment in this @entity1 population in order to establish appropriate treatment programmes such as cognitive remediation.

Dysexecutive syndrome and social adjustment in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity409 :: ('MESH:D008107', 'Disease') :: ['executive dysfunction'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
