The aim of this study was to assess the influence of 3 @entity551 drugs on the @entity209 : @entity2299 , insulin resistance, @entity5052 . There were 39 @entity1 aged 20-55, with mild-to-moderate essential @entity101 . The @entity1 with other serious diseases or treated earlier with @entity165 or @entity414 lowering drugs were excluded. @entity1 were divided into 3 groups, each was treated during 8 weeks with one drug: gr 1-- @entity21594 (T), gr 2-- @entity10202 ER (F), gr 3-- @entity23189 (R). @entity413 and insulin in oral @entity413 tolerance test, I/G proportion, serum lipids and @entity414 were tested before and after therapy. The therapy did not influence lipid parameters: LDL, HDL, @entity412 . In the T group there could be observed a significant reduction of total @entity165 value. Examined drugs did not induce changes in serum @entity1735 . The significant reduction of serum @entity414 could be observed only after F therapy. Analysed drugs are very useful in therapy of @entity101 with @entity209 .

[The effect of analysed XXXX drugs on certain metabolic parameters].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity23189 :: ('MESH:C032302', 'Chemical') :: ['rilmenidine'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity21594 :: ('MESH:C052035', 'Chemical') :: ['trandolapril'] @entity10202 :: ('MESH:D015736', 'Chemical') :: ['felodipine'] @entity1735 :: ('CHEBI:16646', 'Chemical') :: ['carbohydrate'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity5052 :: ('MESH:D033461', 'Disease') :: ['hyperuricemia'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic disorders'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotensive'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose', 'Glucose'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol'] @entity414 :: ('MESH:D014527', 'Chemical') :: ['uric acid']
@entity551 :: (MESH:D007022,Disease) :: ['hypotensive']
