BACKGROUND: The diagnostic value of radiolabeled white blood cells (WBCs) scintigraphy in @entity1764 is well established, but data in the specific context of relapse are lacking. The present study aimed at evaluation of the diagnostic value of WBCs scintigraphy in suspicion of @entity1764 relapse after prior surgical revision. METHODS AND RESULTS: Multiple planar incidences of the chest were acquired 4 and 20  hours after injection of labeled WBC in 43 @entity1 . In case of non-conclusive scintigraphy, a second scan was performed 2-3  weeks after the first one. The diagnosis of @entity281 was based on positive bacteriological results; otherwise @entity1 were followed up for at least 1  year. Out of 39 analyzable @entity1 , 17 (44%) were diagnosed with @entity1764 relapse. After the first scan, 32 of 39 were correctly classified, 2 were false positive, and 5 were not conclusive. After completion of an additional scan in the latter 5 @entity1 , 36 of 39 were correctly classified and 3 were false positive (100% sensitivity, 86% specificity, 85% positive predictive value, and 100% negative predictive value). CONCLUSIONS: In the specific context of suspicion of @entity1764 relapse, the optimal diagnostic value was achieved by repeating the scan when the first one was not conclusive. In this context, a negative WBC scintigraphy was able to rule out @entity281 , with potential major impact on therapeutic management in @entity1 with poor clinical status.

Diagnostic value of (99m)Tc-HMPAO-labeled leukocytes scintigraphy in suspicion of post-sternotomy XXXX relapse.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1764 :: ('MESH:D008480', 'Disease') :: ['mediastinitis']
@entity1764 :: (MESH:D008480,Disease) :: ['mediastinitis']
