UNASSIGNED: We treated a  cohort of 116 @entity1 with @entity263 with three-dimensional conformal hypofractionated radiotherapy to a  total dose of 52.8 Gy in 16 fractions (3.3 Gy per fraction). The correlation between @entity344 and dose-volume parameters was analysed. Comparison of observed incidence of @entity137 and normal tissue complication probability calculated from dose-volume histograms (DVH) of all @entity1 using radiobiological Lyman-Kutcher-Burman model was performed. The results of our study suggest that acute @entity344 >=  grade 2 (G2) is the significant predictor of late @entity137 >=  G2 (p=0.006). Observed incidence of @entity344 >=  G2 was 9.7% and 11.5%, respectively. NTCPs of @entity344 >=  G2 were 11.3% and 2.5%. Observed incidence of late GU @entity137 >=  G2 was 14.2%, @entity25876 was 0.8%. Comparison of calculated probability of acute @entity344 >=  G2 and observed incidence indicates that parameters of radiobiological models are set appropriately. Comparison of observed incidence of late GI and GU complications >=  G2 and calculated NTCPs shows the need of refinement of LKB model parameters for @entity344 >=  G2.   Keywords: @entity263 , radiotherapy, acute and late @entity137 , radiobiological modeling.

Prediction of @entity137 of XXXX radiotherapy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer'] @entity25876 :: ('6554', 'Gene') :: ['NTCP'] @entity344 :: ('MESH:D005767', 'Disease') :: ['acute and late GI and GU complications', 'GI toxicity', 'acute and late gastrointestinal (GI) and genitourinary (GU) toxicity', 'acute and late GI complications', 'acute and late GI toxicities', 'gastrointestinal toxicity']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
