OBJECTIVE: To determine the relative utility of 3 state-of-the-art parathyroid imaging protocols: 1) single time point simultaneous acquisition of @entity10980 and I-123 images with pinhole collimation in the anterior and bilateral anterior oblique projections, 2) single time point simultaneous acquisition of @entity10980 and I-123 images with SPECT-CT, and 3) the combination of protocols one and two. METHODS: Fifty-nine @entity1 with surgical proof of @entity3243 were evaluated retrospectively. All 3 protocols included perfectly co-registered subtraction images created by subtracting the I-123 images from the @entity10980 images, plus an anterior parallel hole collimator image of the neck and upper chest. The pinhole protocol was performed first followed by the SPECT-CT protocol. Three image sets were derived from each study in each @entity1 according to the above protocols. Two experienced observers recorded the size, location and degree of certainty of any identified lesion. RESULTS: The 59 @entity1 had sixty-one @entity652 . For the 2 observers combined, the localization success rate was 88% for the pinhole protocol, 69% for the SPECT-CT protocol, and 81% for the combined protocol. The pinhole protocol detected more @entity652 than the SPECT-CT protocol and missed fewer @entity652 than either the SPECT-CT protocol or the combined pinhole and SPECT-CT protocol (P < 0.01). The 2 protocols that included SPECT-CT provided superior anatomic information relative to the location and size of the @entity3243 . CONCLUSION: The pinhole protocol localized significantly more @entity652 than the SPECT-CT protocol. However, the protocols that included SPECT-CT provided more anatomic information than pinhole imaging alone.

Parathyroid Imaging with Simultaneous Acquisition of XXXX _ I-123: The Relative Merits of Pinhole Collimation and SPECT-CT.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity3243 :: ('MESH:D010282', 'Disease') :: ['parathyroid adenomas'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas'] @entity10980 :: ('D017256', 'Chemical') :: ['Tc-99m-sestamibi']
@entity10980 :: (D017256,Chemical) :: ['Tc-99m-Sestamibi']
