BACKGROUND: @entity158 relief during labour is one of the major concerns in obstetrics; severe @entity158 causes fear of the next pregnancy, and interferes with the mother's family relationship. OBJECTIVE: The aim of this study was to evaluate the analgesic effects of Entonox during labor on reducing the need for @entity6882 ( @entity6882 ) and fetal-maternal complications. METHODS: This double-blind randomized clinical trial was conducted on pregnant @entity1 who were candidates for vaginal delivery in Educational Hospitals of Mashhad University of Medical Sciences, Iran between January 2014 and November 2015. After entering into the inactive phase of labor, @entity1 were randomly allocated to receive inhaled Entonox gas (n=200) or inhale @entity26 (n=200) as a control group. Mothers inhaled the gas at commencement of @entity158 , and ceased as soon as the @entity158 diminished, up to the end of the second stage of labor which was the neonate's birth. Main outcomes were @entity158 score based on NRS (numerical rating scale), duration of delivery, required @entity6882 , maternal complications and satisfaction during labour. Chi-square and Independent T-test were used via SPSS for data analysis and P-value less than 0.05 was considered statistically significant. RESULTS: Four-hundred pregnant @entity1 with a mean age of 26.4  5.9 years were studied. Complications such as @entity390 , @entity391 , dizziness, and drowsiness were reported in 25% of the Entonox group and 23% in the control group (p=0.640). Mean of @entity158 severity score during labor in the Entonox and control groups was 4.5  1.2 and 5.2  1.4, respectively (p<0.001). @entity6882 requirement, significantly was lower in the Entonox group (31.6  11.8 versus 35.7  12.4; p<0.001). CONCLUSION: In our study, Entonox significantly reduced @entity158 during delivery without significant @entity455 . TRIAL REGISTRATION: The trial is registered at the Iranian Clinical Trial Registry (IRCT.ir) with the IRCT identification number IRCT2015102713159N6. FUNDING: This research has been financially supported by Research Council of Mashhad University of Medical Sciences.

Effect of Entonox on reducing the need for XXXX and the Relevant Fetal and Maternal Complications for Painless Labor.

@entity1 :: ('9606', 'Species') :: ['participants', 'women'] @entity455 :: ('MESH:D014652', 'Disease') :: ['increase in maternal and neonatal complications'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['Oxygen'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity6882 :: ('MESH:D008614', 'Chemical') :: ['Meperidine', 'Pethidine', 'pethidine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain', 'labor pain']
@entity6882 :: (MESH:D008614,Chemical) :: ['Pethidine']
