BACKGROUND: Locking compression plates are used in various configurations with lack of detailed information on consequent bone healing. STUDY DESIGN: In this in vivo study in @entity742 5 different applications of @entity2850 ( @entity2850 ) were tested using a 45   oblique osteotomy simulating simple @entity174 pattern. 60 Swiss Alpine @entity742 where assigned to 5 different groups with 12 @entity742 each (Group 1: interfragmentary lag screw and an @entity2850 fixed with standard cortex screws as neutralisation plate; Group 2: interfragmentary lag screw and @entity2850 with locking head screws; Group 3: compression plate technique (hybrid construct); Group 4: internal fixator without @entity174 gap; Group 5: internal fixator with 3mm gap at the osteotomy site). One half of each group (6 @entity742 ) was monitored for 6 weeks, and the other half (6 @entity742 ) where followed for 12 weeks. METHODS: X-rays at 3, 6, 9 and 12 weeks were performed to monitor the healing process. After sacrifice operated tibiae were tested biomechanically for nondestructive torsion and compared to the tibia of the healthy opposite side. After testing specimens were processed for microradiography, histology, histomorphometry and assessment of @entity460 deposition by fluorescence microscopy. RESULTS: In all groups bone healing occurred without complications. Stiffness in biomechanical testing showed a tendency for higher values in G2 but results were not statistically significant. Values for G5 were significantly lower after 6 weeks, but after 12 weeks values had improved to comparable results. For all groups, except G3, stiffness values improved between 6 and 12 weeks. Histomorphometrical data demonstrate endosteal callus to be more marked in G2 at 6 weeks. DISCUSSION AND CONCLUSION: All five configurations resulted in undisturbed bone healing and are considered safe for clinical application.

The influence of different osteosynthesis configurations with locking compression plates ( @entity2850 ) on stability and XXXX healing after an oblique 45   angle osteotomy.

@entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity742 :: ('9940', 'Species') :: ['sheep'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity2850 :: ('MESH:D009408', 'Disease') :: ['LCP', 'locking compression plate']
@entity174 :: (MESH:D050723,Disease) :: ['fracture']
