INTRODUCTION AND OBJECTIVES: To evaluate the use of health care resources and their cost according to the effects of @entity177 in @entity712 @entity1 during 2-year follow-up in a population setting. METHODS: Observational retrospective study based on a review of medical records. The study included @entity1 >=  45 years treated for @entity712 from 2008 to 2010. The @entity1 were divided into 2 groups according to the presence/absence of KF. Main outcome variables were comorbidity, clinical status (functional class, etiology), @entity209 , costs, and new cases of cardiovascular events and @entity177 . The cost model included direct and indirect health care costs. Statistical analysis included multiple regression models. RESULTS: The study recruited 1600 @entity1 (prevalence, 4.0%; mean age 72.4 years; @entity1 , 59.7%). Of these @entity1 , 70.1% had @entity101 , 47.1% had @entity2299 , and 36.2% had @entity6 . We analyzed 433 @entity1 (27.1%) with @entity177 and 1167 (72.9%) without @entity177 . @entity1 with @entity177 were associated with functional class III-IV (54.1% vs 40.8%) and @entity209 (65.3% vs 51.9%, P<.01). The average unit cost was    10 711.40. The corrected cost in the presence of @entity177 was    14 868.20 vs    9364.50 (P=.001). During follow-up, 11.7% @entity1 developed @entity741 , 18.8% developed @entity177 , and 36.1% developed @entity712 exacerbation. CONCLUSIONS: Comorbidity associated with @entity712 is high. The presence of @entity177 increases the use of health resources and leads to higher costs within the National Health System.

Economic impact of @entity712 according to the effects of XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity177 :: ('MESH:D051437', 'Disease') :: ['kidney failure'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic syndrome']
@entity177 :: (MESH:D051437,Disease) :: ['kidney failure']
