BACKGROUND: @entity9285 ( @entity9285 ) is a well-documented treatment of @entity56 . Little is known about potential effects of @entity9285 on the risk of other chronic immune-related diseases. Over the years, a few casuistic reports have caused concern that @entity9285 might act as a trigger of @entity792 . OBJECTIVE: We aimed to investigate the association of @entity9285 with the incidence of @entity792 and @entity741 ( @entity741 ), as well as all-cause mortality. METHODS: All Danish citizens without other known diseases were linked and followed through central registries on medications and hospital admissions. @entity1 receiving @entity9285 and @entity1 receiving conventional allergy treatment (CAT; nasal @entity230 or oral antihistamines) were compared with regard to mortality and development of @entity792 , @entity583 ( @entity583 ), and @entity741 . Cox regression (survival analysis) with age as the underlying time scale was used to estimate relative risks (hazard ratios [HRs] with 95% CIs) associated with @entity9285 compared with CAT adjusted for age, sex, vocational status, and income. RESULTS: During the 10-year study period (1997-2006), a total of 18,841 and 428,484 @entity1 were followed in the @entity9285 and CAT groups, respectively. Receiving @entity9285 was associated with lower mortality (HR, 0.71; 95% CI, 0.62-0.81) and lower incidence of @entity583 (HR, 0.70; 95% CI, 0.52-0.93), @entity741 (HR, 0.88; 95% CI, 0.73-1.05), and @entity792 (HR, 0.86; 95% CI, 0.74-0.99). CONCLUSION: In this registry-based observational study, receiving @entity9285 compared with CAT was associated with lower risk of @entity792 and @entity583 , as well as decreased all-cause mortality.

Association of subcutaneous allergen-specific immunotherapy with incidence of XXXX , @entity741 , and mortality.

@entity1 :: ('9606', 'Species') :: ['Persons', 'persons'] @entity9285 :: ('MESH:D013352', 'Disease') :: ['Subcutaneous allergen-specific immunotherapy', 'SCIT'] @entity56 :: ('MESH:D004342', 'Disease') :: ['IgE-mediated allergic disease'] @entity741 :: ('MESH:D017202', 'Disease') :: ['IHD', 'ischemic heart disease'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity583 :: ('MESH:D009203', 'Disease') :: ['AMI', 'acute myocardial infarction'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmune disease', 'autoimmune diseases']
@entity792 :: (MESH:D001327,Disease) :: ['autoimmune disease']
