OBJECTIVE: To determine the relationship between @entity425 and @entity16 and @entity236 ( @entity236 ) in the patellofemoral joint (PFJ) and if this relationship is modified by @entity12352 . METHODS: The Multicenter @entity571 Study is a cohort study of @entity1 ages 50-79 years with or at risk of @entity626 . Concentric knee extensor strength was measured using an isokinetic dynamometer. @entity12352 was measured using the Insall-Salvati ratio (ISR) on the lateral radiograph, and @entity16 and @entity236 were graded on magnetic resonance imaging in the PFJ. We determined the association between @entity425 with @entity16 and @entity236 in the PFJ among knees with (ISR >= 1.2) and without (ISR <1.2) @entity12352 using multiple binomial regression. RESULTS: A total of 807 knees were studied (mean age 62 years, body mass index 30 kg/m(2) , ISR 1.10) and 64% were from @entity1 . Compared with the knees in the highest strength tertile, those in the lowest had 10.2% (95% confidence interval [95% CI] 3, 18), 9.1% (95% CI 2, 16), and 7.1% (95% CI 1, 13) higher prevalence of lateral PFJ @entity16 , medial PFJ @entity16 , and lateral PFJ @entity236 , respectively. The association between @entity425 with @entity16 and @entity236 was not different between knees with and without @entity12352 in the lateral PFJ. CONCLUSION: @entity425 was associated with PFJ @entity16 and @entity236 . While both @entity12352 and @entity425 were associated with PFJ damage, the combination of the two was not associated with more damage than either of these factors alone.

XXXX , @entity12352 , and structural features of patellofemoral osteoarthritis.

@entity1 :: ('9606', 'Species') :: ['women', 'persons'] @entity626 :: ('MESH:D020370', 'Disease') :: ['knee osteoarthritis'] @entity571 :: ('MESH:D010003', 'Disease') :: ['Osteoarthritis'] @entity16 :: ('MESH:D009422', 'Disease') :: ['cartilage damage'] @entity425 :: ('MESH:D018908', 'Disease') :: ['Quadriceps weakness', 'quadriceps weakness'] @entity12352 :: ('MESH:C535568', 'Disease') :: ['patella alta', 'Patella alta'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow lesions', 'BMLs']
@entity425 :: (MESH:D018908,Disease) :: ['Quadriceps weakness']
