PURPOSE: The fusion imaging modality of positron-emission tomography-computed tomography (PET-CT) has emerged as an important modality in the management of recurrent @entity135 . The aims of this study were to assess the role of PET-CT in the detection of recurrence in treated @entity213 ( @entity213 ) and compare neck PET-CT and contrast-enhanced computed tomography (CECT) in the detection of locoregional recurrence with histopathologic correlation. MATERIALS AND METHODS: The study design was prospective and the study consisted of @entity1 with treated @entity213 referred to the Department of Radiology at Rajiv Gandhi Cancer Institute and Research Center for follow-up or for clinical suspicion of recurrence. PET-CT and CECT neck images were obtained to detect recurrence based on clinical suspicion or as routine follow-up. Comparison of CECT and PET-CT results was performed using receiver operating characteristics (ROC) curves for the detection of locoregional recurrence with histopathologic correlation. RESULTS: Fifty-eight @entity1 with treated @entity213 underwent neck PET-CT and CECT to detect recurrence based on clinical suspicion or as routine follow-up. The sensitivity and specificity of PET-CT for the detection of locoregional recurrence were 100% and 97.37%, which were considerably higher than 85% and 71.05% when using CECT. The ROC curve and its analysis showed that regional PET-CT is superior to neck CECT in the detection of locoregional recurrence (P  = .02). When considering recurrence at the metastatic site, the sensitivity and specificity of PET-CT were 100% and 97.06%. PET-CT also detected second @entity5 in 2 @entity1 . CONCLUSION: PET-CT not only is superior to conventional CECT in the detection of recurrence at locoregional and lymph node sites, but also plays a role in the restaging of recurrent @entity5 and the detection of distant metastases and second @entity5 . PET-CT, if included in routine post-treatment @entity213 follow-up or in a protocol for suspected recurrence, may have a major impact on the management of @entity1 after treatment of @entity213 .

Positron emission tomography-computed tomography: a superior and one-stop shop modality for treated XXXX compared with conventional tomography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumors', 'tumors'] @entity213 :: ('MESH:C535575', 'Disease') :: ['head and neck squamous cell carcinoma', 'HNSCC']
@entity135 :: (MESH:D006258,Disease) :: ['head and neck carcinoma']
