OBJECTIVE: To evaluate whether one-step gestational @entity6 screening recommended by The International Association of the @entity6 (IADPSG) is associated with better maternal, perinatal, or neonatal outcomes than the two-step Carpenter-Coustan screening. METHODS: In this before-after retrospective cohort study conducted between July 1, 2010, and December 31, 2013, we compared Carpenter-Coustan and IADPSG screening in @entity1 with singleton pregnancies. All @entity1 diagnosed with gestational @entity6 received intensive teaching, home @entity413 monitoring, and medications as indicated. The primary outcome was the rate of large-for-gestational-age neonates. Secondary outcome measures were @entity8455 (greater than 4,000 g), primary cesarean delivery, neonatal intensive care unit admission, @entity3152 , @entity1468 , and @entity3638 . We determined that a sample size of 2,782 per group was sufficient to detect a 2% difference in the primary outcome between groups with 80% power assuming a 10% incidence in the before group. The groups were compared using Fisher exact test for proportions and a    test for odds ratios. RESULTS: In the before (Carpenter-Coustan) group, 513 (17%) of the 2,972 @entity1 were diagnosed with gestational @entity6 , and in the after (IADPSG) group, 847 (27%) of the 3,094 @entity1 were so diagnosed (P<.001). There was no significant difference in rates of large for gestational age, 10% and 9%, respectively (P=.25). The IADPSG group had a significantly higher primary cesarean delivery rate-16% compared with 20% (P<.001), but there were no significant differences in any other pregnancy outcomes. CONCLUSION: Although one-step screening was associated with more @entity1 being treated for gestational @entity6 , it was not associated with a decrease in large-for-gestational-age or macrosomic neonates but was associated with an increased rate of primary cesarean delivery. Our results did not support the IADPSG-recommended screening protocol.

Gestational Diabetes Screening: The International Association of the XXXX Compared With Carpenter-Coustan Screening.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3152 :: ('MESH:D007752', 'Disease') :: ['preterm delivery'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes and Pregnancy Study Groups', 'diabetes'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['preeclampsia'] @entity8455 :: ('MESH:D005320', 'Disease') :: ['macrosomia'] @entity3638 :: ('MESH:D006932', 'Disease') :: ['hyperbilirubinemia'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity6 :: (MESH:D003920,Disease) :: ['Diabetes and Pregnancy Study Groups']
