BACKGROUND: @entity120 ( @entity120 ) was recently recognized as a common complication of @entity454 ( @entity454 ) that causes an increased risk of mortality. Epidemiological data for this disorder in earlier stages of @entity740 ( @entity740 ) and its association with cardiovascular (CV) morbidity are scarce. METHODS: We retrospectively analyzed 2,351 Chinese @entity740 @entity1 with complete clinical records and echocardiography data between Jan 2008 and May 2012. The @entity1 were divided into the following 6 groups: @entity740 Stages 1-4; Stage 5 for those not on or initiated on hemodialysis for <3 months; and Stage 5D for the @entity1 undergoing hemodialysis for >= 3 months. The prevalence of @entity120 and CV morbidity was investigated, and their association was evaluated with a logistic regression model. RESULTS: @entity120 was detected in 426 @entity1 (18.1%). Mild, moderate and severe @entity120 was diagnosed in 12.1%, 4.9% and 1.1% of the @entity1 , respectively. Severe @entity120 was detected in @entity740 Stages 5 and 5D. CV morbidity was found in 645 @entity1 (27.4%). Compared with the non- @entity120 group, the @entity120 group had a higher risk for @entity299 but not for @entity66 risk. @entity120 severity was associated with cardiac morbidity risk [odds ratio (95% CI) for mild @entity120 : 1.79 (1.30-2.47); moderate @entity120 : 2.75 (1.73-4.37); severe @entity120 : 3.90 (1.46-10.42)]. CONCLUSIONS: Our study showed for the first time the epidemiology profile of @entity120 across the spectrum of @entity740 . Mild-to-moderate @entity120 occurs with more frequency in advanced @entity740 , and severe @entity120 is scarce in non- @entity454 @entity740 . @entity120 in @entity740 is associated with cardiac but not @entity66 , with increasing cardiac morbidity seen with increasing @entity120 severity. Evidence from prospective studies addressing @entity120 in this population is needed to predict @entity299 .

Pulmonary Hypertension: Epidemiology in Different XXXX Stages and Its Association with Cardiovascular Morbidity.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['cerebrovascular disease'] @entity120 :: ('MESH:D006976', 'Disease') :: ['Pulmonary hypertension', 'PH'] @entity740 :: ('MESH:D051436', 'Disease') :: ['CKD', 'chronic kidney disease'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac disease', 'cardiac events'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal disease', 'ESRD']
@entity740 :: (MESH:D051436,Disease) :: ['CKD']
