OBJECTIVE: To clarify the potential of quantitative intravenous myocardial contrast echocardiography (MCE) for physiologic assessment of the @entity6128 ( @entity6128 ) @entity850 . METHODS: We studied 38 @entity1 with suspected @entity453 . MCE was performed by continuous infusion of Levovist and intermittent ultrasonic exposure. Images were obtained from the apical four-chamber view at rest and after @entity4341 infusion. The background-subtracted intensity versus pulsing interval plots were fitted to an exponential function,Y=A(1 e-ss), to obtain the plateau level (A) and rate of rise (ss) of background-subtracted intensity both at rest and after @entity4341 infusion. We compared the results with those of exercise thallium-201 single-photon emission computed tomography (SPECT). RESULTS: Of the 38 @entity1 , 18 @entity1 exhibited redistribution in the @entity6128 territories with SPECT (group A), although 20 did not (group B). The ss reserve ( @entity3130 /rest) in group A was significantly lower than those in group B (0.8 +/- 0.5 versus 2.0 +/- 1.1, P < 0.001), while the A reserve did not differ between the two groups (1.2 +/- 0.6 versus 1.0 +/- 0.5, P = NS). The ss reserve <1.1, which was the optimal cutoff value, provided sensitivity of 79% and specificity of 84% for the presence of redistribution in SPECT. CONCLUSIONS: Quantitative intravenous MCE allows us to estimate physiologic severity of the @entity2791 in the clinical setting.

Physiologic assessment of left anterior descending coronary artery stenosis by quantitative intravenous myocardial contrast echocardiography in XXXX : comparison with exercise single-photon emission computed tomography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3130 :: ('MESH:C562470', 'Disease') :: ['DIP'] @entity2791 :: ('MESH:D012078', 'Disease') :: ['LAD stenosis'] @entity4341 :: ('MESH:D004176', 'Chemical') :: ['dipyridamole'] @entity6128 :: ('MESH:D020243', 'Disease') :: ['left anterior descending artery', 'LAD'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis']
@entity1 :: (9606,Species) :: ['humans']
