The efficacy and safety of two manual toothbrushes (Dentrust and the Oral-B P35) were evaluated in orthodontic @entity1 classified by their treating orthodontist as having established @entity2522 . Fifty-seven healthy adolescent subjects, who were fully bonded and banded with fixed orthodontic appliances, were randomly assigned to use one of the two toothbrushes for the duration of the four-month study. The subjects were given instructions with their new assigned toothbrush and agreed to use only these products at home, twice a day between orthodontic visits. On evaluation days at one, two and four months the @entity1 reported to the clinic having not brushed for 12-16 hours, and were evaluated for plaque area and @entity2522 in this single blind study. @entity2522 scores decreased significantly in the Dentrust group from baseline to the conclusion of the study. There was no significant statistical decline in @entity2522 in the Oral-B P35 group until the four-month evaluation. Overnight plaque formation scores were similar for both groups during the study. After brushing for a timed one-minute period, both toothbrushes removed significant plaque area throughout the study. On total plaque levels, the Dentrust group was significantly lower on after-toothbrushing plaque area mean scores compared to the Oral-B P35 group at two and four months. No side effects were reported or observed during the study attributed to the use of the assigned toothbrushes.

Four-Month Assessment of the Dentrust and Oral-B P35 Toothbrushes in Orthodontic XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2522 :: ('MESH:D005891', 'Disease') :: ['Gingivitis', 'gingivitis']
@entity1 :: (9606,Species) :: ['Patients']
