PURPOSE: To compare outcomes and complication rates of trabeculectomy with either transconjunctival @entity1138 ( @entity1139 ) or subconjunctival @entity1139 application. METHODS: Retrospective cohort study-35 eyes in subconjunctival group and 29 eyes in transconjunctival group. All surgeries were performed by 1 surgeon (E.A.) at 1 center with an average follow-up duration of 40 to 51 months. RESULTS: The mean percentage intraocular pressure reduction at final follow-up was with 44.4  25.3% reduction in the subconjunctival group compared with 48.0  24.6% reduction in the transconjunctival group, with no statistical significant difference between the 2 groups (P=0.57). Both groups also showed a >40% reduction in intraocular pressure in approximately 67% of eyes. There were no cases of @entity3225 . There was 1 reported case of @entity548 following subconjunctival application of @entity1139 . There were similar low rates of @entity86 and requirement for postoperative application of @entity1487 . There was a greater incidence of @entity5891 in the subconjunctival group (5 vs. 1) as well as @entity1143 (8 vs. 4). One @entity1 underwent revision of trabeculectomy and this was in the subconjunctival group. CONCLUSION: Transconjunctival application of @entity1139 offers a safe and effective method of performing trabeculectomy with adjunctive @entity1139 with lower rates of complication than subconjunctival application.

Outcomes of Trabeculectomy With Transconjunctival Application Versus Subconjunctival Application of XXXX .

@entity1143 :: ('MESH:D010996', 'Disease') :: ['choroidal effusions'] @entity1 :: ('9606', 'Species') :: ['patient'] @entity548 :: ('MESH:D006470', 'Disease') :: ['choroidal hemorrhage'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin C'] @entity1139 :: ('CHEBI:27504', 'Chemical') :: ['MMC'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative bleb leakage'] @entity5891 :: ('MESH:D006988', 'Disease') :: ['hyphema'] @entity3225 :: ('MESH:D009877', 'Disease') :: ['endophthalmitis'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-fluorouracil']
@entity1138 :: (MESH:D016685,Chemical) :: ['Mitomycin C']
