OBJECTIVE: To assess the value of an elevated luteinizing hormone (LH)-to-follicle-stimulating hormone (FSH) ratio in predicting development of a dominant follicle when ovulation induction is implemented with @entity4082 ( @entity5635 ) or @entity4672 in @entity1 with @entity3610 ( @entity3610 ). STUDY DESIGN: Retrospective review of 312 monitored cycles between 2007 and 2012. All @entity1 met the diagnostic criteria set by the 2006 Androgen Excess- @entity3610 Society and had baseline LH and FSH levels drawn. Only ovulation induction with @entity5635 or @entity4672 was included. Primary outcome was development of a dominant follicle of >=  18 mm. RESULTS: The development of a dominant follicle was significantly associated with clinical pregnancy. The development of a dominant follicle was also higher in the @entity4672 group as compared to the @entity5635 group (87.6% [155/177] vs. 62.2% [84/135], p < 0.001). Furthermore, treatment with @entity4672 significantly increased the odds of forming a dominant follicle when LH/FSH ratio was >=  1 (odds ratio [OR] 7.69, CI 3.69-16.02). When LH/ FSH ratio was < 1, @entity4672 had no significant effect on dominant follicle development (OR of 3.63, CI 0.92-14.25). CONCLUSION: LH/FSH ratio >=  1 could be useful as a predictive tool to identify which subgroup of @entity3610 @entity1 may be more successful in forming a dominant follicle when using @entity4672 as compared to @entity5635 .

Predictive Value of Elevated LH/FSH Ratio for Ovulation Induction in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity5635 :: ('D002996', 'Chemical') :: ['CC'] @entity3610 :: ('MESH:D011085', 'Disease') :: ['polycystic ovary syndrome', 'PCOS'] @entity4672 :: ('MESH:C067431', 'Chemical') :: ['letrozole'] @entity4082 :: ('MESH:D002996', 'Chemical') :: ['clomiphene citrate']
@entity3610 :: (MESH:D011085,Disease) :: ['Polycystic Ovary Syndrome']
