OBJECTIVES: To analyze the influence of the different pre - cystectomy factors, both clinical and pathological, in the follow up of @entity1 with no @entity41 ( pT0) in the pathological examination of the radical cystectomy specimen as predictors of @entity5 recurrence. Secondly we intend to compare overall survival, disease free survival and cancer-specific survival with the rest of cystectomy @entity1 in our series. METHODS: Between 1985 and 2010, radical cystectomy was performed in 280 @entity1 with @entity150 , being 41 pT0 (14.6%). We analyzed potential predictors for overall survival and disease-free survival: age, sex , number of transurethral resections of @entity150 before cystectomy , @entity5 type , @entity5 grade, @entity5 stage, @entity5 size, number of @entity5 , associated Cis and previous instillations. We used univariate analysis of Cox regression. Survival analysis was performed using Kaplan - Meier curves and log-rank test. RESULTS: Mean age was 61.7 years and 37 @entity1 were males (90.2%). Stages before cystectomy were @entity2558 in eight (19.5%) , pT2 in 31 (75.6%) and Cis in two (4.9 %) with @entity5 grade III in 37 (90.2%). Cystectomy specimens revealed the presence of @entity1358 in 38 (92.7%) cases. The median number of pre-cistectomy-TURBT was one. Eleven @entity1 (26.8%) received intravesical instillations. Six @entity1 (14.63 %) had @entity5 recurrence and 10 (24.4 %) died from causes unrelated to the disease. None of the variables analyzed was statistically significant in the univariate analysis as a predictor of @entity5 recurrence. With a median follow up of 70 months (3-272) disease-free survival and overall survival at five years were 85.9% and 72.8% respectively. Compared to the non pT0 cystectomies in our series, pT0 had a statistically significant difference for better recurrence-free survival (63.4 % and 36.8%, respectively in pT0 and no-pT0 @entity1 ) (p   0,05). CONCLUSIONS: According to the results, we have found a better outcome for pT0 @entity1 after cystectomy compared to those with @entity41 . We have not found any pre - cystectomy predictive factor related to disease-free survival and overall survival.

Predictive factors of evolution of XXXX after pT0 radical cystectomy due to @entity150 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2558 :: ('58492', 'Gene') :: ['pT1'] @entity41 :: ('MESH:D018365', 'Disease') :: ['residual tumor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity1358 :: ('MESH:D002292', 'Disease') :: ['papillary transitional cell carcinoma'] @entity150 :: ('MESH:D001749', 'Disease') :: ['bladder tumor', 'bladder cancer']
@entity1 :: (9606,Species) :: ['patients']
