@entity1800 of the upper respiratory airways can lead to a delayed @entity1800 @entity2172 (VOM) caused by a diffusion of viruses/virus particles through the round window membrane and resulting in @entity1274 . The treatment of choice is immediate paracentesis, evacuation of all fluids from the middle ear cavity, and haemorrheological infusions. However, in some cases, persistent symptoms may be an indication for a surgical approach using mastoidectomy. In high-resolution computed tomography, an extended small-sized pneumatisation of the mastoid cells with complete shading was found in these non-responsive cases. Therefore, a direct means of inner ear affliction through weak parts of the labyrinthine bone may be hypothesised. @entity1 suffering from a toxic @entity389 (TIEL) following a common cold, treated over a 10-year period in a Tertiary Care Centre (N  =  52, 57 ears), were identified and the morphological characteristics of the temporal bones of affected @entity1 were examined by means of high-resolution computed tomography (hrCT). The findings were compared with a matched control group of 64 normal ears (CONT). Measurements included the grade of pneumatisation, distances within the temporal bones and Hounsfield units (HU) at defined anatomical structures. In the TIEL group, we found a small-sized pneumatisation in 79.4  % and a medium-sized pneumatisation in 10.9  %, thus differing from the CONT group and the literature data. Thickness of the bone wall of the lateral semicircular canal (LSC) and distances within the aditus ad antrum were significantly reduced in the TIEL group. HU's were markedly lower in the TIEL group at the precochlea, the LSC, and dorsolateral to the promentia of the LSC. There was a correlation between the HU's at the prominentia of the LSC and the @entity393 (p  =  0.002). Persisting interosseous globuli, as described in 1897 by Paul Manasse, form an osseochondral network within the otic capsule and may be responsible for a direct means of toxic @entity389 . The CT-morphometric results support this thesis. In the group of these @entity1 (TIEL) a CT-scan and in non-responders to conservative treatment a surgical approach by mastoidectomy is recommended.

@entity389 following otitis XXXX with effusion: a comparative CT-study regarding the morphology of the inner ear.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2172 :: ('MESH:D010033', 'Disease') :: ['media'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['Viral infections', 'viral otitis'] @entity1274 :: ('MESH:D006319', 'Disease') :: ['sensorineural hearing loss'] @entity389 :: ('MESH:D007759', 'Disease') :: ['inner ear lesion', 'inner ear infection'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss']
@entity2172 :: (MESH:D010033,Disease) :: ['media']
