UNASSIGNED: @entity1 papillomaviruses are DNA viruses that infect skin or mucosal cells. In the genital tract HPV (especially types 6 and 11) cause genital warts, the commonest viral @entity2953 . At least 13 of the more than 100 known HPV genotypes are oncogenic "high-risk" genotypes. The 2 most common of these (genotypes 16 and 18) cause approximately 70% of all @entity5 . @entity4771 @entity1799 are associated with other @entity5 , anus, vagina, vulva and penis, and @entity5 of the head and neck and current estimates are that 5.2% of all @entity5 are HPV associated. In industrialised countries cervical @entity5 is controlled by secondary intervention other HPV associated @entity5 are increasing in incidence and the burden of @entity66 in @entity1 is now comparable to that in @entity1 in economically developed countries. Randomized control trials with the quadrivalent HPV VLP vaccine demonstrate robust antibody responses and high efficacy against genital warts anal precancers in @entity1 . Few countries have recommended male vaccination on the basis that this is not cost effective. However gender-neutral vaccination has been recommended in the USA, Canada, Austria, and Australia. Careful cost effective modeling has preceded these decisions showing that when the burden of disease in @entity1 is included in the models then, depending upon coverage, vaccine price, and other factors male vaccination can become cost effective.

HPV vaccination in @entity1 and XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Human', 'men'] @entity2953 :: ('MESH:D012749', 'Disease') :: ['sexually transmitted disease'] @entity66 :: ('MESH:D004194', 'Disease') :: ['HPV associated disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['anogenital cancers', 'cancers', 'cancer', 'cervical cancers', 'malignancies'] @entity4771 :: ('MESH:C537751', 'Disease') :: ['Oncogenic HPVs particularly'] @entity1799 :: ('333760', 'Species') :: ['HPV 16']
@entity1 :: (9606,Species) :: ['men']
