UNASSIGNED: OBJECT The aim of this study was to elucidate the invasiveness, effectiveness, and feasibility of MRI-guided stereotactic radiofrequency thermocoagulation (SRT) for @entity10128 ( @entity10128 ). METHODS The authors examined the clinical records of 100 consecutive @entity1 (66 male and 34 female) with intractable @entity410 ( @entity410 ) caused by @entity10128 , who underwent SRT as a sole surgical treatment between 1997 and 2013. The median duration of follow-up was 3 years (range 1-17 years). Seventy cases involved pediatric @entity1 . Ninety percent of @entity1 also had other types of @entity410 ( @entity410 ). The maximum diameter of the HHs ranged from 5 to 80 mm (median 15 mm), and 15 of the @entity5 were giant HHs with a diameter of 30 mm or more. Comorbidities included precocious puberty (33.0%), @entity146 (49.0%), and @entity1032 (50.0%). RESULTS A total of 140 SRT procedures were performed. There was no adaptive restriction for the giant or the subtype of @entity10128 , regardless of any prior history of surgical treatment or comorbidities. @entity1 in this case series exhibited delayed precocious puberty (9.0%), @entity4611 (2.0%), and @entity1017 (7.0%), besides the transient @entity1640 symptoms after SRT. Freedom from @entity410 was achieved in 86.0% of @entity1 , freedom from other types of @entity410 in 78.9%, and freedom from all @entity410 in 71.0%. Repeat surgeries were not effective for @entity410 . @entity410 freedom led to disappearance of @entity146 and to intellectual improvement. CONCLUSIONS The present SRT procedure is a minimally invasive and highly effective surgical procedure without adaptive limitations. SRT involves only a single surgical procedure appropriate for all forms of epileptogenic @entity10128 and should be considered in @entity1 with an early history of @entity410 .

MRI-guided stereotactic radiofrequency thermocoagulation for 100 XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['gelastic seizures', 'seizures', 'non-GS', 'Seizure', 'GS'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['mental retardation'] @entity146 :: ('MESH:D001523', 'Disease') :: ['behavioral disorder', 'behavioral disorders'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity1640 :: ('MESH:D007027', 'Disease') :: ['hypothalamic'] @entity4611 :: ('MESH:D010900', 'Disease') :: ['pituitary dysfunction'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity10128 :: ('MESH:C537158', 'Disease') :: ['HH', 'hypothalamic hamartoma']
@entity10128 :: (MESH:C537158,Disease) :: ['hypothalamic hamartomas']
