Several studies addressed the question whether needle-EMG causes elevation of muscle enzymes [ @entity492 -aminotransferase, @entity493 -aminotransferase, @entity880 -dehydrogenase, @entity908 -phosphokinase (CPK), isoenzyme-MB, aldolase] and @entity880 with conflicting results. However, these studies used sterilizable needle electrodes and different protocols and methods to record EMGs and determine muscle enzymes. This study examined if muscle enzymes are elevated immediately after or 24 h following EMGs with disposable, concentric needle-electrodes, and if they are dependent on age, sex, muscle, number of investigated sites and previous CPK-elevation. In 53 subjects, 24 @entity1 , 29 @entity1 , aged 17-88 years, muscle enzymes were determined before, immediately after and 24 h following EMG with disposable, concentric needle-electrodes. Muscle enzymes were not different before, immediately after and 24 h following the EMG. Muscle enzymes were not different between @entity1 <or=60 or >60 years of age. Apart from higher CPK in @entity1 than @entity1 , muscle enzymes were not different between the genders. Apart from CPK, muscle enzymes were not different between the brachial biceps and anterior tibial muscle. Muscle enzymes were not different if <or=20 or >20 sites were investigated and were independent on pre-EMG CPK-levels. In conclusion this study shows that muscle enzymes do not increase immediately or 24 h following EMG with disposable, concentric needle-electrodes, irrespective of age, gender, muscle, number of investigated sites and pre-EMG CK-levels.

Influence of disposable, concentric needle electrodes on muscle enzyme and XXXX serum levels.

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'patients', 'men'] @entity908 :: ('MESH:D003401', 'Chemical') :: ['creatine'] @entity492 :: ('CHEBI:29995', 'Chemical') :: ['aspartate'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity493 :: ('CHEBI:16449', 'Chemical') :: ['alanine']
@entity880 :: (MESH:D019344,Chemical) :: ['lactate']
