INTRODUCTION: A gastrostomy placement is frequently performed in pediatric @entity1 who require long-term enteral tube feeding. However, data on efficacy, perioperative complications and @entity354 ( @entity354 ) after laparoscopic gastrostomy (LAG) placement is limited. The aim of this study is to evaluate long-term efficacy and adverse events after LAG in a large cohort and determine whether routine preoperative 24-h pH monitoring should be used to predict @entity354 . METHOD: A retrospective observational cohort study was performed including 300 @entity1 (75  % neurologically impaired) that underwent LAG. RESULTS: After a median follow-up of 2.63  years, feeding was successful in 95.9  % of @entity1 . Weight-for-length z-scores significantly increased (p  <  0.0005). Major complications were seen in only 6 @entity1 (2.0  %), but minor complications occurred frequently (73.6  %). Overall incidence of @entity354 remained unchanged after LAG. Sensitivity and specificity of preoperative pH monitoring were 17.5 and 76.9  %, respectively. CONCLUSION: LAG placement in pediatric @entity1 leads to successful feeding in 96  % of @entity1 and serious adverse events are rare. However, the minor complication rate is high. Overall incidence of @entity354 does not increase after LAG. Preoperative 24-h pH monitoring is not a reliable tool to predict @entity354 . This invasive investigation technique should therefore not be routinely performed.

Efficacy and adverse events of laparoscopic gastrostomy placement in XXXX : results of a large cohort study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity354 :: ('MESH:D005764', 'Disease') :: ['GER', 'postoperative gastroesophageal reflux', 'postoperative GER']
@entity1 :: (9606,Species) :: ['children']
