STUDY DESIGN: Prospective follow-up study. OBJECTIVE: Evaluation of the diagnostic assessment and clinical significance of the intravertebral cleft in @entity158 ( @entity3814 ) treated with percutaneous vertebroplasty ( @entity12468 ). SUMMARY OF BACKGROUND DATA: @entity1 with @entity158 @entity3814 with intravertebral clefts provide a unique and possibly superior indication for @entity12468 . However, comparative studies are scarce, and the results are conflicting. The extent of the difference attributable to interobserver variation in the identification of an intravertebral cleft is currently unknown. METHODS: A total of 102 @entity1 received @entity12468 for 197 @entity158 long-standing @entity3814 and were prospectively observed, using a @entity158 -intensity numerical-rating scale for back @entity158 , the 36-Item Short Form Health Survey quality-of-life questionnaire, and routine spinal radiographs. Three experienced examiners retrospectively examined all preoperative radiographs and magnetic resonance imaging (MRI) T1-weighted and short-tau-inversion-recovery (STIR) sequences and the direct postoperative computed tomographic scans for the presence of an intravertebral cleft. Disagreements were re-examined and discussed for consensus. RESULTS: Interobserver agreement for the detection of an intravertebral cleft was moderate on preoperative radiography (k, 0.55-0.59) and substantial on preoperative MRI (k, 0.71-0.79) and postoperative computed tomography (k, 0.67-0.85). On the basis of consensus, 42 (21.3%) clefts were detected. The associated sensitivity of preoperative radiography was low (31.7%-48.8%), but the specificity was high (94.7%-99.3%). The diagnostic performance of preoperative MRI T1-weighted and STIR sequences was excellent, with both high sensitivity (85.7%-88.1%) and high specificity (89.7%-98.1%). @entity158 decrease and increase in quality of life obtained from @entity12468 were ultimately comparable with @entity1 without intravertebral clefts but was obtained more gradually during the first postoperative year. An intravertebral cleft was a strong risk factor for the occurrence of @entity27760 (odds ratio, 4.29; 95% confidence interval, 1.51-12.2; P = 0.006). CONCLUSION: There is variation between observers in the identification of an intravertebral cleft, and the identification of an intravertebral cleft is not always straightforward. For preoperative assessment, we recommend MRI with T1-weighted and STIR sequences. Regarding @entity1 -reported outcome, @entity1 with long-standing @entity3814 with intravertebral clefts benefit from @entity12468 , but, compared with @entity1 with @entity3814 without intravertebral clefts, the benefit obtained was not superior and may be delayed.

The intravertebral cleft in XXXX treated with percutaneous vertebroplasty: diagnostic assessment and clinical significance.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity27760 :: ('MESH:C563017', 'Disease') :: ['cortical cement leakage'] @entity12468 :: ('CHEBI:53245', 'Chemical') :: ['PVP'] @entity3814 :: ('MESH:D050815', 'Disease') :: ['OVCFs'] @entity158 :: ('MESH:D010146', 'Disease') :: ['painful, long-standing osteoporotic vertebral compression fractures', 'Pain', 'pain', 'painful']
@entity158 :: (MESH:D010146,Disease) :: ['painful long-standing osteoporotic vertebral compression fractures']
