A combined retrospective and prospective study of 86 @entity1 with @entity8 was conducted to determine whether the level of @entity644 was a good predictive index of @entity74 . The @entity1 fell into three groups: Group A, 31 @entity1 with @entity644 of less than 1 g/day, Group B, 31 @entity1 with @entity644 of 1 to 3.5 g/day; and Group C, 24 @entity1 with @entity644 of more than 3.5 g/day. The groups are comparable in age of presentation, sex ratio, and duration of study and showed no difference in serum @entity1011 levels, @entity1011 clearance, incidence of @entity101 or incidence of @entity8 . Compared with the @entity1 in the other groups, those in Group C did not have increased incidence of @entity74 . Nevertheless, they have a higher incidence of @entity1985 (p less than 0.001), a lower incidence of macroscopic haematuria (p less than 0.05), lower serum albumin (p less than 0.05) and heavier @entity644 (p less than 0.01). Severity of @entity644 had no significant correlation with the severity of renal histopathologic changes. Clinical observations divided the 24 @entity1 with @entity1985 range @entity644 into three well-defined groups with different prognoses. Six @entity1 had @entity74 with decreasing @entity644 . Five of these remained @entity101 and their initial renal biopsy showed advanced pathologic changes. Thirteen @entity1 had persistent @entity644 although the renal function remained unchanged. Three of these were treated with @entity134 but failed to respond, and their renal histopathologic changes were usually moderate. The remaining five @entity1 showed good response to @entity134 treatment although two became @entity134 -dependent. Their renal histopathology showed mild alteration. Our findings suggest that severe @entity644 in @entity8 does not inevitably indicate a poor prognosis.

@entity1985 range XXXX --a good predictive index of disease in @entity8 ?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity8 :: ('MESH:D007674', 'Disease') :: ['IgA nephropathy', 'impaired renal function'] @entity1985 :: ('MESH:D009404', 'Disease') :: ['nephrotic', 'nephrotic syndrome'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'hypertensive'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['steroid'] @entity74 :: ('MESH:D030342', 'Disease') :: ['progressive disease'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity644 :: (MESH:D011507,Disease) :: ['proteinuria']
