The sensitivity of the commonly used stress tests for the diagnosis of @entity453 was analyzed in 46 @entity1 with significant occlusion (greater than or equal to 70% luminal diameter obstruction) of only one major coronary artery and no prior @entity583 . In all @entity1 , thallium-201 perfusion imaging (both planar and seven-pinhole tomographic) and 12 lead electrocardiography were performed during the same graded treadmill exercise test and radionuclide angiography was performed during upright bicycle exercise. Exercise rate-pressure (double) product was 22,307 +/- 6,750 on the treadmill compared with 22,995 +/- 5,622 on the bicycle (p = NS). Exercise electrocardiograms were unequivocally abnormal in 24 @entity1 (52%). Qualitative planar thallium images were abnormal in 42 @entity1 (91%). Quantitative analysis of the tomographic thallium images were abnormal in 41 @entity1 (89%). An exercise ejection fraction of less than 0.56 or a new wall motion abnormality was seen in 30 @entity1 (65%). Results were similar for the right (n = 11) and left anterior descending (n = 28) coronary arteries while all tests but the planar thallium imaging showed a lower sensitivity for isolated circumflex @entity455 (n = 7). The specificity of the tests was 72, 83, 89 and 72% for electrocardiography, planar thallium imaging, tomographic thallium imaging and radionuclide angiography, respectively. The results suggest that exercise thallium-201 perfusion imaging is the most sensitive noninvasive stress test for the diagnosis of @entity453 .

XXXX : results of exercise electrocardiography, thallium-201 myocardial perfusion imaging and radionuclide angiography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity453 :: ('MESH:D003324', 'Disease') :: ['single vessel coronary artery disease', 'coronary artery disease'] @entity455 :: ('MESH:D014652', 'Disease') :: ['artery disease'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction']
@entity453 :: (MESH:D003324,Disease) :: ['Assessment of single vessel coronary artery disease']
