OBJECTIVES: To identify potential risk factors influencing early and late outcome following the arterial switch operation (ASO) for transposition of the great arteries associated with @entity1757 including double-outlet right or left ventricle. METHODS: All @entity1 who underwent ASO in our department until August 2000 (n=105) were included in this study. There were 77 transpositions of the great arteries with @entity1757 , 22 @entity1147 hearts and six @entity1 with double-outlet morphology. The median age at operation was 24 days. Aortic arch obstruction was present in 25 @entity1 ; in 13 of these @entity1 , a repair with aortic arch reconstruction was done before ASO. The usual coronary artery pattern was present in 59% of the @entity1 . In six @entity1 , we found an intramural course of at least one coronary artery. The @entity1757 was closed with a patch through the right atrium (n=35), the aorta (n=25), the pulmonary artery (n=25) or the right ventricle (n=3); in 17 @entity1 a combined approach was necessary. RESULTS: There were five hospital @entity204 (4.7%, 95% confidence limit 2-11%). The median duration of follow-up was 72 months. Fourteen @entity1 underwent 15 reoperations 33 months after repair (median), eight for right @entity3585 or @entity850 . Four late @entity204 occurred, two due to complications related to @entity453 . Statistical analysis revealed no significant risk factor whatsoever correlating with @entity204 or need for reoperation. Survival after 12 years was 91.6%, and freedom from reoperation was 82.6%. Latest follow-up data showed that 13% of @entity1 were in NYHA class II and/or required medical treatment; 87% were in NYHA class I. CONCLUSIONS: ASO associated with patch closure of @entity1757 can be performed early in life with a low risk of mortality (<5%), low incidence of reintervention (<15%) and promising long-term outcome.

Transposition of the great arteries associated with XXXX : surgical results and long-term outcome.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3585 :: ('MESH:D014694', 'Disease') :: ['ventricular outflow tract obstruction'] @entity1757 :: ('MESH:D006345', 'Disease') :: ['ventricular septal defect'] @entity1147 :: ('MESH:D004310', 'Disease') :: ['Taussig-Bing'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery anomalies'] @entity850 :: ('MESH:D003251', 'Disease') :: ['neopulmonary stenosis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'deaths']
@entity1757 :: (MESH:D006345,Disease) :: ['ventricular septal defect']
