BACKGROUND: Left hepatic trisectionectomy (LHT) is a challenging major anatomical hepatectomy with a high complication rate and a worldwide experience that remains limited. The aim of this study was to describe changes in surgical practice over time, to analyse the outcomes of @entity1 undergoing LHT for @entity5 , and to identify factors associated with morbidity and mortality. METHODS: A cohort study was undertaken of @entity1 who underwent LHT at a single tertiary hepatobiliary referral centre between January 1993 and March 2013. Univariable and multivariable analysis was used to identify factors associated with short- and long-term outcomes following LHT. RESULT: Some 113 @entity1 underwent LHT for @entity14 (57), @entity201 (22), @entity1419 (12) and @entity157 (11); 11 @entity1 had various other indications. Overall morbidity and 90-day mortality rates were 46  0 and 9  7 per cent respectively. Overall 1- and 3-year survival rates were 71  3 and 44  4 per cent respectively. @entity99 and intraoperative blood transfusion were independent predictors of postoperative morbidity, whereas blood transfusion was the only factor predictive of in-hospital mortality. Time period analysis revealed a decreasing trend in blood transfusion, duration of hospital stay, and postoperative morbidity and mortality in the last 5 years. CONCLUSION: Morbidity, mortality and long-term survival after LHT support its use in selected @entity1 with a significant @entity5 burden.

Clinical outcomes of left hepatic trisectionectomy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour', 'hepatobiliary malignancy'] @entity201 :: ('MESH:D018281', 'Disease') :: ['hilar cholangiocarcinoma'] @entity1419 :: ('MESH:C535533', 'Disease') :: ['intrahepatic cholangiocarcinoma'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal liver metastasis'] @entity157 :: ('MESH:D006528', 'Disease') :: ['hepatocellular carcinoma'] @entity99 :: ('MESH:D056486', 'Disease') :: ['Total hepatic vascular exclusion']
@entity5 :: (MESH:D009369,Disease) :: ['hepatobiliary malignancy']
