OBJECT: Our study aimed to evaluate the efficiency of flow-diverting stents (FDS) in treating unruptured, intradural dissecting @entity438 (VADAs). Additionally, the effect of FDS on the aneurysmal flow pattern was investigated by performing in  vivo flow analysis using parametric color coding (PCC). METHODS: We evaluated 11 @entity1 with unruptured, intradural VADAs, treated with FDS. Pre- and postinterventional DSA-series were postprocessed by PCC, and time-density curves were calculated. The parameters aneurysmal inflow-velocity, outflow-velocity and relative time-to-peak (rTTP) were calculated. Pre- and postinterventional values were compared and correlated with the occlusion rate after six months. RESULTS: Follow-up DSA detected 10 @entity439 , meaning an occlusion rate of 91%. No procedure-related morbidity and mortality was found. Flow analyses revealed a significant reduction of aneurysmal inflow- velocity and prolongation of rTTP after FDS deployment. Concerning @entity439 , the postinterventional outflow-velocity turned out to be a marginally statistically significant predictor. A definite threshold value (-0.7 density change/s) could be determined for the outflow-velocity that allows prediction of complete @entity439 with high sensitivity and specificity (100%). CONCLUSIONS: Using FDS can be considered an efficient and safe therapy option in treating unruptured, intradural VADA. From in  vivo flow analyses the postinterventional aneurysmal outflow-velocity turned out to be a potential predictor for later complete @entity439 . Here, it might be possible to determine a threshold value that allows prediction of @entity439 with high specificity and sensitivity. As fast, applicable and easy-to-handle tool, PCC could be used for procedural monitoring and might contribute to further treatment optimization.

Flow-diverting stents allow efficient treatment of unruptured, intradural dissecting XXXX : An explanatory approach using in  vivo flow analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms occluded', 'aneurysm occlusion'] @entity438 :: ('MESH:D002532', 'Disease') :: ['aneurysms of the vertebral artery']
@entity438 :: (MESH:D002532,Disease) :: ['aneurysms of the vertebral artery']
