The authors have carried out the laboratory and clinical studies of @entity37737 (CDX). The results were as follows; The sensitivity was measured by plate dilution method on 27 strains of @entity794 and @entity526 , 26 strains of @entity3274 isolated from @entity1 . The distribution of sensitivity of @entity794 was 3.13-12.5 microgram/ml and the peak of distribution was 3.13 microgram/ml and 6.25 microgram/ml, of @entity526 was 6.25 microgram/ml by 10(8) cells/ml. And the distribution of sensitivity of @entity3274 was 6.25-25 microgram/ml and its peak was 6.25 microgram/ml by 10(8) cells/ml. CDX were given orally at dose of 10 mg/kg to 3 children. The serum levels of CDX were 10.5 +/- 1.78 microgram/ml, 15.8 +/- 3.25 microgram/ml, 12.0 +/- 0.41 microgram/ml and 3.9 +/- 0.9 microgram/ml at 0.5, 1, 2, 4 hours after administration respectively, and was 2.3 +/- 0.48 microgram/ml at 6 hours. The urinary excretion rate was 55.6% up to 8 hours after administration. CDX were administered to 39 cases of pediatric @entity166 (26 cases with @entity5389 , 5 cases with @entity1964 , 3 cases with UTI, 2 cases with @entity9280 , each one case with @entity3617 , cervical @entity3892 ). And CDX were given 25.0-65.2 mg/kg daily. Clinical results obtained were above good in all cases. No side effects were observed in any cases, except for one case, with @entity294 , 6 cases with the elevation of serum transaminase and 1 case with @entity1712 .

[Laboratory and clinical studies of XXXX (author's transl)].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3617 :: ('MESH:D001991', 'Disease') :: ['bronchitis'] @entity1712 :: ('MESH:D004802', 'Disease') :: ['eosinophilia'] @entity3892 :: ('MESH:D004823', 'Disease') :: ['lymphadenitis and epididymitis'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity794 :: ('1280', 'Species') :: ['S. aureus'] @entity5389 :: ('MESH:D014069', 'Disease') :: ['tonsillitis'] @entity3274 :: ('573', 'Species') :: ['K. pneumoniae'] @entity9280 :: ('MESH:D007169', 'Disease') :: ['impetigo'] @entity1964 :: ('MESH:D004760', 'Disease') :: ['enterocolitis'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious disease'] @entity526 :: ('562', 'Species') :: ['E. coli'] @entity37737 :: ('MESH:D002434', 'Chemical') :: ['cefadroxil']
@entity37737 :: (MESH:D002434,Chemical) :: ['cefadroxil']
