@entity5683 ( @entity5683 ) are rare neoplasms of the central nervous system whose optimal management is not well defined. The Surveillance Epidemiology and End Results (SEER) Database from 1978 to 2009 was queried to define population-based outcomes for all @entity1 with @entity5683 . @entity1 demographic data, histological classification ( @entity2846 [ @entity2846 ], atypical @entity2846 [aCPP], and @entity9204 [ @entity9204 ]), extent of surgery, and use of @entity1161 ( @entity1161 ) as part of an initial course of therapy were analyzed for impact on @entity1349 ( @entity1349 ) and cause-specific survival (CSS). Chemotherapy data were not available within the SEER database. A total of 349 @entity1 with @entity5683 were identified (120 CPCs, 26 aCPPs, and 203 CPPs). @entity1 with @entity9204 presented at a younger age (median 3, mean 14.8  years) relative to @entity2846 (median 25, mean 28.4  years; p  <  0.0001). Histology was a significant predictor of @entity1349 , with 5-year @entity1349 rates of 90, 77, and 58  % for @entity2846 , aCPP, and @entity9204 , respectively. Older age and male sex were prognostic for worse @entity1349 and CSS for @entity2846 . Only extent of surgery had a significant impact on survival for @entity9204 . The use of adjuvant @entity1161 in @entity1 with @entity9204 undergoing surgery was not associated with a significantly improved @entity1349 (p  =  0.17). For @entity1 undergoing GTR without @entity1161 as part of an initial course of therapy, estimated 5- and 10-year @entity1349 were 70  % (  7  %) and 67  % (  8  %), respectively. Prospective data are required to define the optimal combination of surgery with adjuvant therapies, including chemotherapy.

XXXX epidemiology and outcomes: implications for surgical and radiotherapeutic management.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'Patient'] @entity5683 :: ('MESH:D016545', 'Disease') :: ['CPTs', 'Choroid plexus tumors'] @entity1161 :: ('MESH:D011832', 'Disease') :: ['radiation therapy', 'RT'] @entity2846 :: ('MESH:D020288', 'Disease') :: ['CPP', 'choroid plexus papilloma'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival'] @entity9204 :: ('MESH:C562943', 'Disease') :: ['CPC', 'choroid plexus carcinoma']
@entity5683 :: (MESH:D016545,Disease) :: ['Choroid plexus tumor']
