BACKGROUND: Bacterial translocation (BT) describes the passage of bacteria residing into the gastrointestinal tract, through the intestinal mucosa barrier to sterile tissues such as mesenteric lymph nodes (MLN) and other organs. This phenomenon has not been thoroughly studied in @entity1 with @entity130 to date, and an association between BT and @entity86 has not been well established so far. METHODS: MLNs from 36 @entity1 with @entity1661 were removed during laparotomy and cultured to detect BT. Postoperative infectious complications in these @entity1 were registered, and both phenotypical and molecular typings (through multilocus sequencing) were carried out for microorganisms isolated from MLN and @entity86 sites. Associations between clinical variables, BT presence, and @entity86 development were established. RESULTS: BT was detected in 33% of the @entity1 (n = 12). @entity86 were present in 22.2% of the @entity1 (n = 8). A significant statistical difference was found between @entity86 in @entity1 with BT evidence (41.6%), when compared with @entity1 without BT (12.5%; p = 0.047). Bacteria isolated from infection sites were the same as those cultured in MLN in 40% of the cases (n = 2 of 5), allowing us to establish causality between BT and @entity86 . CONCLUSIONS: There is higher risk of BT in @entity130 @entity1 , and it is associated with a significant @entity86 . An @entity1661 index >= 10 was found to be associated with the development of BT. This is the first study describing BT among @entity1 with @entity1661 , where causality is confirmed at molecular level.

Bacterial translocation in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1661 :: ('MESH:D000008', 'Disease') :: ['abdominal trauma'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative infections', 'Postoperative infections', 'increase of postoperative infections', 'postoperative infection'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity86 :: (MESH:D019106,Disease) :: ['abdominal trauma and postoperative infections']
