OBJECTIVE: This study evaluated the efficacy of intravaginal @entity1421 gel in comparison with that of a Foley catheter for cervical ripening and induction of labor. STUDY DESIGN: Consecutive @entity1 with unfavorable cervix requiring preinduction cervical ripening and induction of labor at term gestation were asked to participate in the study. One hundred and two @entity1 were assigned to treatment with intravaginal @entity1421 gel (group 1) and 122 @entity1 underwent the placement of an intracervical Foley catheter (group 2). After a maximum of three applications of intravaginal @entity1421 gel (18h) or after 18h from Foley catheter insertion @entity398 was administered to @entity1 not in active labor. Labor profiles and pregnancy and neonatal outcome were compared between groups. RESULTS: The groups were comparable in term of demographic characteristics, indications for induction of labor, Bishop score at admission. The induction to labor time and the induction to delivery time were similar between groups. The cesarean sections rate was higher in group 1 than in group 2 (26.5 versus 14.7%, P<0.05). This remained significant when the analysis was restricted to nulliparous @entity1 (32.3 versus 14.2%). The incidence of @entity293 , @entity5870 , and febrile morbidity was similar between groups. CONCLUSION: For preinduction cervical ripening, the Foley catheter is a valid alternative to the application of intravaginal @entity1421 gel and it is associated with a lower cesarean rate in nulliparous @entity1 .

Extra-amniotic Foley catheter and XXXX gel for cervical ripening at term gestation.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity398 :: ('MESH:D010121', 'Chemical') :: ['oxytocin'] @entity1421 :: ('MESH:D015232', 'Chemical') :: ['prostaglandin E(2)'] @entity5870 :: ('MESH:D002821', 'Disease') :: ['chorioamnionitis'] @entity293 :: ('MESH:D014552', 'Disease') :: ['urinary tract infections']
@entity1421 :: (MESH:D015232,Chemical) :: ['prostaglandin E(2)']
