UNASSIGNED: Background and study aims: Training using an animal model is generally recommended before performing endoscopic submucosal dissection (ESD) in @entity1 . This study aimed to clarify the suitability of an isolated porcine stomach as an animal training model for @entity356 . Materials and methods: Study 1: six experienced endoscopists performed ESDs of six simulated lesions located in six locations in an isolated porcine stomach (1, lower third [L]/ greater curvature [Gre]; 2, L/ anterior wall [Ant]; 3, L/ posterior wall [Post]; 4, upper third [U]/ Gre; 5, U/Ant; 6, U/Post). The procedure times (s/cm(2)) were compared among the different lesion locations. A questionnaire (scored 1-5) completed by the endoscopists was used to assess the difference in the difficulty compared to the @entity1 stomach of the three steps of the ESD procedure (injection, incision and dissection). Study 2: the thicknesses of the mucosal layers were histologically evaluated among the six locations in three porcine and two @entity1 stomachs. Results: Study 1: the procedure speed was significantly slower at L/Gre and U/Gre in the porcine stomachs (P=0.0004). The questionnaire responses revealed a tendency toward similarity between the lower regions of the @entity1 and porcine stomachs at L/Ant, L/Post, U/Ant and U/Post during the dissection step (P=0.056). In contrast, the injection and incision steps at L/Gre in the porcine stomach were shown to differ in difficultly level (both P=0.0006). Study 2: the mucosal layers in the porcine stomachs were significantly thicker than those in the @entity1 stomachs in the lower areas, especially L/Gre. Conclusions: The difficulty of ESD and the histological features of the porcine stomachs were coincident with those of the @entity1 stomachs at L/Ant, L/Post, U/Ant and U/Post. These parts of the porcine stomach may be suitable as animal training models for @entity356 .

Which part of a porcine stomach is suitable as an animal training model for XXXX ?

@entity1 :: ('9606', 'Species') :: ['humans', 'human'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric ESD']
@entity356 :: (MESH:D013274,Disease) :: ['gastric endoscopic submucosal dissection']
