Background: Salivary dysfunction is the most common side effect associated with I-131 therapy in @entity1 with @entity259 . The purpose of this study was to evaluate the effect of parotid gland massage on radioisotope accumulation in the salivary gland. Methods: Sixty @entity1 were included in this study. Using @entity1497 , two salivary scans were performed in all @entity1 . In 30 @entity1 (massage groups), parotid gland massage was performed between the two salivary gland scans, whereas in the other 30 @entity1 (no massage groups) no procedure was performed between the two scans. Total counts of both parotid glands and accumulation ratios were calculated. Results: In the massage groups, no difference was observed between the mean parotid gland counts of first and second images (8556.9    3333.4 count vs. 8598.3    3341.3 count, p = 0.39). In the no massage groups, the mean parotid gland count on second images was significantly higher than that on first images (8581.2    3618.0 count vs. 9096.4    3654.0 count, p < 0.01). Mean accumulation ratio in the massage groups was significantly lower than that in the no massage groups (0.5    3.3% vs. 6.8    3.8%, p < 0.01). Furthermore, the massage groups had a higher percentage of @entity1 with a negative accumulation ratio than the no massage groups (43.3% vs. 0%, p < 0.01). Conclusions: Parotid gland massage can reduce @entity1497 accumulation in the parotid gland, and thus, should be helpful to prevent salivary damage associated with I-131 therapy.

Effect of Parotid Gland Massage on Parotid Gland XXXX Uptake.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1497 :: ('MESH:D013670', 'Chemical') :: ['Tc-99m pertechnetate'] @entity259 :: ('MESH:D013964', 'Disease') :: ['differentiated thyroid cancer']
@entity1497 :: (MESH:D013670,Chemical) :: ['Tc-99m pertechnetate']
