BACKGROUND: @entity5 commonly metastasize to the liver. Although surgical resection is considered a treatment option for @entity1 with localized @entity3 confined to the liver, the longterm survival benefit of liver resection has not been clearly demonstrated. We examined the survival of @entity1 undergoing liver resection for this disease. STUDY DESIGN: Between 1984 and 1995, we evaluated 38 @entity1 with liver-only @entity3 from @entity5 , including 21 @entity4303 , 13 islet cell, and 4 atypical neuroendocrine @entity5 . Data from a combined prospective and retrospective database and a @entity5 registry were analyzed. Of these @entity1 , 15 underwent complete resection of all known disease. The remaining 23 @entity1 , who also had disease confined to the liver, had comparable @entity5 burden but were believed to be unresectable. The longterm survival rates of these two groups were compared. RESULTS: @entity1 who underwent liver resection did not differ from those who were unresectable with regard to age, pathology, primary @entity5 site, serum alkaline phosphatase levels, or percentage of the liver involved. All resections were complete, leaving no residual disease, and consisted of lobectomy (n = 3), segmentectomy (n = 1), and wedge resections (n = 11). There were no operative deaths. @entity1 who underwent hepatic resection had a significantly longer survival than unresected @entity1 . Although median survival had not been reached in resected @entity1 , the median survival in the unresectable group was 27 months. @entity1 who underwent liver resection had a higher 5-year actuarial survival (73% versus 29%). CONCLUSIONS: Hepatic resection in selected @entity1 with isolated liver @entity3 from @entity5 may prolong survival. This conclusion was reached by comparing our resected group with an unresectable group with similar @entity5 burden.

Isolated liver @entity3 from XXXX : does resection prolong survival?

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Neuroendocrine tumors', 'neuroendocrine tumors', 'neoplasms'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity4303 :: ('MESH:D002276', 'Disease') :: ['carcinoid'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity5 :: (MESH:D009369,Disease) :: ['neuroendocrine tumors']
