BACKGROUND: The etiology of @entity29 , @entity30 ( @entity30 ) and @entity31 ( @entity31 ), is unknown. These diseases have a higher incidence in industrialized countries and their pathogenesis involves an over-reaction of the immune system. A genetic factor is believed to predispose to the development of @entity32 in response to an unidentified stimulus. @entity281 in childhood may modulate future immune responses. @entity8143 , particularly @entity2040 , stimulate Th2 immune responses. It has been hypothesized that the absence of these parasitic infections, as seen in economically developed countries, favors a Th1 response that may result in the clinical appearance of @entity30 later in life. OBJECTIVE: To determine the prevalence of @entity380 mansoni antibodies in Puerto Ricans with @entity29 and controls. METHODS: Serum from 92 Puerto Ricans with @entity8787 and 106 controls was screened for @entity383 adult microsomal antigens (MAMA) using the FAST:ELISA assay. Those positive were confirmed with an enzyme-linked immunoelectrotransfer blot test. RESULTS: Seven serum samples (3 @entity31 and 4 controls) were positive for S. mansoni antibodies. There was no significant difference between groups in gender, municipality of origin or seroprevalence of @entity2040 . The control group was slightly older than the @entity8787 group. CONCLUSIONS: Our study did not demonstrate an inverse relation between @entity2040 and @entity8787 . However, the decreasing prevalence of @entity2040 in the general population of Puerto Rico may account for this result.

Seroprevalence of XXXX in Puerto Ricans with @entity29 .

@entity32 :: ('MESH:D007249', 'Disease') :: ['chronic inflammation'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity29 :: ('MESH:D015212', 'Disease') :: ['Inflammatory Bowel Disease', 'Inflammatory Bowel Diseases'] @entity383 :: ('99802', 'Species') :: ['S. mansoni'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Exposure to infections'] @entity380 :: ('6183', 'Species') :: ['Schistosoma'] @entity2040 :: ('MESH:D012552', 'Disease') :: ['Schistosomiasis'] @entity8787 :: ('MESH:C535541', 'Disease') :: ['IBD'] @entity8143 :: ('MESH:D063726', 'Disease') :: ['Parasitosis'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"]
@entity380 :: (6183,Species) :: ['Schistosoma mansoni']
