PURPOSE: We have introduced magnifying colonoscopy into clinical practice and analyzed its diagnostic efficacy, especially regarding the ability to distinguish neoplastic from non-neoplastic @entity1127 . METHODS: The materials consisted of 923 @entity1127 . After identifying the lesions during normal colonoscopy, a dye was sprayed, and then the zoom apparatus of the colonoscope was used to make a magnified observation at a maximum 100 times magnification. We classified the crypt orifices into six categories and labeled them A to F as follows: A, a medium round appearance; B, an @entity134 appearance; C, an elliptic appearance; D, a small, round appearance; E, a cerebriform appearance; F, no apparent structural appearance. RESULTS: Forty-two of 923 @entity1127 did not reveal any clear images of crypt patterns. The percentage of histologically neoplastic change in the lesions classified as A, B, C, D, E, and F were 10, 15.9, 93.7, 100, 94.8, and 87.5 percent, respectively. When we considered types A and B to represent a crypt pattern of non- @entity1313 , and types C, D, E, and F to represent @entity1313 , and when the lesions that did not show any clear images were classified as a misjudgment, the diagnostic accuracy of @entity1313 (sensitivity) was 92 percent and that of non- @entity1313 (specificity) was 73.3 percent. Overall, the diagnostic accuracy in differentiating neoplastic from non- @entity1313 was 88.4 percent. Twenty-three @entity1313 that were misjudged to be non-neoplastic were histologically @entity652 with mild atypia in 22 and @entity652 with moderate atypia in 1. CONCLUSION: Magnifying colonoscopy was considered to be useful in determining the indications for colonoscopic removal.

Efficacy of magnifying endoscopy in the differential diagnosis of neoplastic and non-neoplastic XXXX of the large bowel.

@entity134 :: ('CHEBI:35341', 'Chemical') :: ['asteroid'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenoma'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['neoplastic lesions']
@entity1127 :: (MESH:D011127,Disease) :: ['polyps']
