BACKGROUND: With increased survival of perinatally @entity645 - infected adolescents due to antiretroviral therapy (ART), the focus of @entity645 care has shifted to health-related quality of life (HRQoL) as a measure of disease progression, effects of ART co-morbidity and prognosis. We assessed factors associated with better HRQoL in perinatally @entity645 -infected adolescents in Uganda by determining the associations between @entity458 ( @entity458 ) or lifestyle experiences on HRQoL. METHODS: In a cross-sectional study, data on @entity458 , lifestyle experiences, socio demographic factors, communication with parents on sexuality and satisfaction of @entity458 services in ART clinics were collected from 614 @entity645 perinatally infected adolescents aged 10-19 using an interviewer-administered survey questionnaire. HRQoL data were collected using the Medical Outcomes Study @entity645 Health Survey instrument (MOS- @entity645 ). Factors associated with better HRQoL were analysed using multiple logistic regression. RESULTS: The mean age was 16.2        2.1  years, 362 (58.8  %) were females and 210 (34.2  %) were sexually active. Adolescents on ART were twice likely to present with better physical health (AOR   =   2.07, 95  % CI: 1.24-3.46) and four times more likely to present with better mental health (AOR   =   3.9, 95  % CI: 2.22-6.92) than those who were not on ART. There were no statistically significant associations between @entity458 (ever had sex, ever been pregnant, condom use, contraceptive use) or life style factors and physical health or mental health. Those with secondary or tertiary education were more likely to present with a better mental health (AOR   =   5.3, 95  % CI: 1.86-15.41) compared those who had attained primary or no education. @entity1 who desired to have a @entity1 in future more likely (AOR 1.7, 95  % CI: 1.05-3.00) to present with a better mental health. Lack of communication with guardians on sexuality (AOR   =   0.6, 95  % CI: 0.40-0.89), or dissatisfaction with @entity458 services (AOR 0.34, 95  % CI: 0.18-0.62) were associated with poorer mental health. CONCLUSION: Among perinatally @entity645 -infected adolescents in Uganda, being on ART was associated with better physical and mental health while lack of communication with guardians on sexuality or dissatisfaction with @entity458 services was associated with poor mental health. Adolescents with pregnancy intentions were more likely to have a better mental health.

Reproductive health and lifestyle factors associated with health-related quality of life among perinatally XXXX -infected adolescents in Uganda.

@entity1 :: ('9606', 'Species') :: ['Participants', 'child'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity458 :: ('MESH:D020018', 'Disease') :: ['SRH', 'sexual and reproductive health']
@entity645 :: (57667,Species) :: ['HIV']
