OBJECTIVE: @entity1375 is a late side effect after curative radiotherapy in the head and neck region. Superselective intra-arterial chemotherapy (SSIAC), when combined with radiation (SSIAC-R), shows higher control potential for locally advanced @entity135 , which is attributable to a delivery of higher concentrations of chemotherapeutic agents. However, it could enhance damages in the normal tissues. @entity1375 is a late adverse effect after curative radiotherapy in the head and neck region. This study focuses on the toxic effect of treatment modality for thyroid function. METHODS: A retrospective analysis was performed to examine @entity1 ' thyroid function after SSIAC-R for laryngeal and @entity5 . RESULTS: @entity1375 was observed in 21 (77.8%) of 27 @entity1 receiving SSIAC-R, 4 (33.3%) of 12 @entity1 treated with radiation alone, and 7 (41.1%) of 17 who underwent systemic chemoradiotherapy. The number of administered vessels significantly correlated with the incidence of developing @entity1375 among SSIAC-R treated @entity1 (P=0.03). CONCLUSION: Concurrent setting of SSIAC with radiation significantly raises the possibility of @entity1375 . Therefore, monitoring late complications of therapeutic procedures is essential during follow-up visits.

Thyroid dysfunction after intra-arterial chemotherapy for hypopharyngeal and XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1375 :: ('MESH:D007037', 'Disease') :: ['Hypothyroidism', 'hypothyroidism'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck cancers'] @entity5 :: ('MESH:D009369', 'Disease') :: ['hypopharyngeal cancer']
@entity5 :: (MESH:D009369,Disease) :: ['laryngeal cancer']
