Surgery remains the only curative approach to @entity201 . Despite operative difficulties concerning @entity5 location, vascular involvement or hepatic invasion curative resection (i.e. achievement of @entity5 free margins) carries good survival rates and is associated with low morbidity and mortality. Our experience with 31 @entity1 with @entity201 operated during the years 1993-1999 is presented. Twenty-five @entity1 were found to have @entity201 , 3 @entity189 of mid-choledochus and 3 @entity201 . All @entity1 were evaluated by a diagnostic protocol including laparoscopy and laparoscopic ultrasound. Surgery consisted of local resection of the @entity5 with Roux en Y hepaticojejunostomy reconstruction. Three @entity1 had concomitant hepatic resection for @entity201 while 3 @entity1 had pancreaticoduodenectomy for @entity201 . @entity420 was diagnosed in all @entity1 . Curative resection was achieved in 19 @entity1 and palliative resection (microscopically involved resected margins) in 12. One @entity1 died at 60 days postop (3.5% mortality). Postoperative complications included @entity255 occurring in 10 @entity1 who were referred with biliary drains, intraabdominal abscess (2 @entity1 ) and biliary leakage (1 @entity1 ) all treated conservatively. Overall survival rate was 82% at one year, 73% at two years and 45% at 5 years. When comparing curative resection with palliative resection, survival rates were 92% versus 71% for 1 year, 72% versus 50% for 2 year and 57% versus 14% for 5 years. Selection of @entity1 using Laparoscopic Ultrasound combined with aggressive surgical approach enable curative or palliative resection 15 the only treatment modality which is significantly improved survival.

[Aggressive surgical treatment for XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity201 :: ('MESH:D018281', 'Disease') :: ['hilar cholangiocarcinoma', 'cholangiocarcinoma', 'distal cholangiocarcinoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['Adenocarcinoma'] @entity255 :: ('MESH:D002761', 'Disease') :: ['cholangitis']
@entity201 :: (MESH:D018281,Disease) :: ['cholangiocarcinoma']
