BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) appears as a useful tool to alleviate @entity9 but only few data are available for the long-term benefit of this treatment. METHODS: Here we report the effects of rTMS sessions, considered as a possible therapy for @entity158 relief after a failure of different medications in @entity1 with @entity9 . We review here the prospectively collected data of the first forty @entity1 treated as follow: 20  Hz stimulation delivered over the contralateral primary motor cortex (M1), each 3-4  weeks. RESULTS: A total of 440 rTMS sessions was collected (mean sessions number: 11, range: 1-37, follow-up 312  days on average, maximum 2.8  years). After four sessions, nine @entity1 (22.5%) discontinued rTMS because of a lack of efficiency (<10% @entity158 ). The other 31 @entity1 (77.5%) had a cumulative effect across sessions leading to a mean @entity158 relief of 41% for a duration of 15.6  days. A correlation was observed between @entity158 relief in the first session and long-term @entity158 relief (R  =  0.649. p  =  5.6*10(-6) ). Both intensity and duration of @entity158 relief were significantly better for @entity1 with persistent laser evoked potentials (LEPs, p  =  0.049 and 0.0018). We did not observe any @entity4237 . CONCLUSION: These results suggest that repeated sessions of 20  Hz rTMS over M1 are interesting in clinical practice for the treatment of selected @entity1 with @entity158 . Both the cumulative effects across the first sessions and the long duration of @entity158 should impact further randomized trials that are warranted to conclude formally on rTMS efficiency in @entity158 .

Robot-guided neuronavigated rTMS as an alternative therapy for XXXX : Clinical experience and long-term follow-up.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4237 :: ('MESH:D000160', 'Disease') :: ['adverse-effects'] @entity9 :: ('MESH:D009437', 'Disease') :: ['neuropathic pain', 'central (neuropathic) pain'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain-relief', 'central pain', 'pain']
@entity9 :: (MESH:D009437,Disease) :: ['central (neuropathic) pain']
