BACKGROUND: The valid operative standard for @entity459 ( @entity459 ) consists of cervicotomy and presentation of all parathyroid glands. This operative technique features the macroscopic identification of the responsible @entity652 . It also has the advantage of detecting multiglandular disease. The increasing sensitivity of preoperative localization methods and the possibility of intra-operative measurement of parathyroid hormone prepared the way for minimally invasive procedures. METHODS: All @entity1 with @entity459 were examined by cervical sonography and sestamibi scintigraphy of the parathyroid glands. @entity1 eligible for the described procedure had to comply to the following inclusion criteria: biochemical evidence of @entity459 , localization of one unequivocally enlarged parathyroid gland on two corresponding imaging results; no former surgery or radiation to the neck; no @entity1376 ; no suspected @entity259 ; and no secondary or recurrent @entity2742 . We used an operative technique first described by Miccoli in 1997. Before preparation and at 2, 10 and 15 min after exstirpation of the @entity3243 , peripheral blood was drawn. The operation was terminated when a 50% decrease of preoperative @entity461 levels was reached. RESULTS: During a 12-month period (1 December 1997 to 30 November 1998), 13 @entity1 with @entity459 of a total of 59 @entity1 (22%) with @entity2742 ( @entity459 and sHPT) were operated on employing this minimally invasive procedure. In three @entity1 , the operative technique had to be converted to the conventional procedure due to superior @entity652 in two cases and a dorsoesophageal @entity652 in one case. The procedure could thus be successfully completed in ten @entity1 . The overall failure rate was zero in all @entity1 with regard to the underlying disease. There was one temporary, recurrent @entity3746 . The mean overall length of the hospital stay was 3 days. CONCLUSION: The minimally invasive video-assisted parathyroidectomy for localized single-gland @entity652 is a new and attractive surgical therapy option for @entity459 due to improved @entity1 comfort, shortened length of hospital stay and favorable cosmetic results. This may lead to one-day surgery and, therefore, to a reduction of overall costs.

Minimally invasive video-assisted parathyroidectomy--selective approach to localized single gland XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity459 :: ('MESH:D049950', 'Disease') :: ['pHPT', 'primary hyperparathyroidism'] @entity3746 :: ('MESH:D014826', 'Disease') :: ['laryngeal-nerve palsy'] @entity1376 :: ('MESH:C564546', 'Disease') :: ['multinodular goiter'] @entity3243 :: ('MESH:D010282', 'Disease') :: ['parathyroid adenoma'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas', 'adenoma'] @entity259 :: ('MESH:D013964', 'Disease') :: ['carcinoma of the thyroid'] @entity2742 :: ('MESH:D006961', 'Disease') :: ['hyperparathyroidism'] @entity461 :: ('5741', 'Gene') :: ['PTH']
@entity652 :: (MESH:D000236,Disease) :: ['adenoma']
