BACKGROUND: Recent studies have demonstrated that non-high-density lipoprotein @entity165 (non-HDL-C) can predict the risk of @entity65 among general population without @entity301 ( @entity301 ). However, few studies have investigated the predictive value of non-HDL-C for long-term prognosis in @entity1 with @entity301 . The purpose of this study was to investigate whether non-HDL-C can predict long-term @entity65 in @entity1 with @entity301 who underwent coronary artery bypass grafting (CABG). METHODS: We enrolled 1074 consecutive @entity1 who underwent CABG at Juntendo University Hospital between 1984 and 1994, and obtained mortality data through 2000. We divided the @entity1 into 2 groups by the median non-HDL-C level at baseline (180 mg/dL) and used Kaplan-Meier method with log-rank test for survival analyses. Cox proportional-hazard regression model was used to calculate the relative risk (RR) of @entity204 . RESULTS: The mean follow-up period was 10.6  3.5 years. The survival rate of @entity204 was significantly lower in the high non-HDL-C group than that in the low non-HDL-C group (log-rank test; p=0.006). Furthermore, in proportional regression analysis adjusted for conventional coronary risk factors, @entity209 , statin treatment, and use of artery bypass graft, the increased levels of non-HDL-C were significant and independent predictor of @entity204 beyond other lipid parameters (RR1.22; by 10 mg/dL non-HDL-C increasing, 95% confidence interval 1.03-1.44; p<0.05). CONCLUSIONS: The increased levels of non-HDL-C were significantly associated with an increased risk of @entity204 . Baseline non-HDL-C levels may be a practical predictor of long-term @entity204 in @entity1 with @entity301 after CABG.

Non-high-density lipoprotein XXXX is a practical predictor of long-term @entity204 after coronary artery bypass grafting.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity301 :: ('MESH:D003327', 'Disease') :: ['CHD', 'coronary heart disease'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic syndrome'] @entity204 :: ('MESH:D003643', 'Disease') :: ['cardiac death'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular events'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity165 :: (MESH:D002784,Chemical) :: ['cholesterol']
