OBJECTIVE: To show the feasibility and the safety of peritoneal @entity189 (PC) evaluation by single-incision flexible endoscopy (SIFE) and to compare it to single-incision rigid endoscopy (SIRE). BACKGROUND: Direct peritoneal visualization, either by laparotomy or laparoscopy, continues to be the gold standard in diagnosing PC. We reported, in animal study, that combining single-incision laparoscopic surgery and flexible endoscopy improved evaluation of the peritoneal cavity in a live porcine model and in four @entity1 cadavers. METHODS: @entity1 , undergoing surgical exploration for diagnosis and staging of PC, were included in a prospective study. Using a superiority design a sample size of 47 @entity1 was determined. Through a single incision, a standardized peritoneoscopy was conducted with rigid (SIRE) and with flexible endoscope (SIFE). Primary outcome was the access success rates for the 13 regions of the @entity298 Index (PCI). RESULTS: Overall access to the 13 regions of PCI was successful in 83  % of the cases with SIRE and in 91.1  % with SIFE (p  <  10(-10)). SIFE access rates were superior to SIREs' in the regions: R1 (87.2 vs. 61.7  %, p  =  0.002), R2 (87.2 vs. 66  %, p  =  0.004), R3 (85.1 vs. 59.6  %, p  =  0.001) and R6 (80.9 vs. 61.7  %, p  =  0.008). The mean PCI was higher (p  <  10(4)) with SIFE 12.77 (  11.97) than with SIRE 11.77 (  11.63). CONCLUSION: This prospective, comparative study shows that SIFE was significantly superior to SIRE in the exploration of some difficult-to-access peritoneal areas, located in regions 1, 2, 3 and 6. These two minimally invasive staging procedures are safe, feasible and have to be seen as complementary rather than competing.

Single-incision flexible endoscopy (SIFE) for detection and staging of peritoneal XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'human', 'patients'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomatosis'] @entity298 :: ('MESH:D010538', 'Disease') :: ['Peritoneal Carcinomatosis']
@entity189 :: (MESH:D002277,Disease) :: ['carcinomatosis']
