BACKGROUND/AIMS: Surgical resection is a standard treatment of @entity157 , but liver @entity82 is known to be associated to a high @entity5 recurrence rate. METHODOLOGY: A retrospective study of 55 consecutive @entity1 (37 males, 18 females) suffering from @entity157 having undergone surgical resection. @entity157 developed in 29 @entity1 with normal liver (group A) and in 26 @entity1 with @entity409 ( @entity409 ) (group B). @entity1 were significantly older and at high-risk in Group B. RESULTS: Radical liver resection was achieved in 98% (100% in group A; 96% in group B). Overall 2-month mortality was 2% (0% in group A; 4% in group B). The 5-year overall and disease-free survival was respectively 55% and 35%. However, the 5-year overall and disease-free survival was significantly better in Group A (71% and 59%) compared to Group B (37% and 6%) (p < 0.001), respectively. Multivariate statistical analysis demonstrated that age > 50 years, poor @entity5 differentiation and presence of satellite nodules were significant independent adverse predictive factors of overall and disease-free survival. CONCLUSIONS: Resection of HCC is safe and effective with satisfactory overall and disease-free survival rates, except when underlying @entity409 and poor @entity5 differentiation are present.

Prognostic risk factors of survival after resection of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity409 :: ('MESH:D008107', 'Disease') :: ['CLD', 'chronic liver disease'] @entity157 :: ('MESH:D006528', 'Disease') :: ['Hepatocellular carcinoma', 'hepatocellular carcinoma']
@entity157 :: (MESH:D006528,Disease) :: ['hepatocellular carcinoma']
