PURPOSE: The aim of this study was to evaluate the diagnostic and prognostic role of metabolic parameters of FDG PET/CT in @entity1 with @entity1419 ( @entity1419 ). METHODS: From December 2008 to December 2013, 76 FDG PET/CT scans performed for initial staging of @entity1419 in a single institution (57 male and 19 female; mean age 68        9  years) were retrospectively reviewed. @entity1 with history of other known @entity5 were excluded. Detection rates of regional lymph node and distant @entity3 by FDG PET/CT were analyzed in comparison with conventional imaging modalities such as CT or MRI. Metabolic parameters including maximum, peak and mean standardized uptake values (SUVmax, SUVpeak, SUVmean), metabolic @entity5 volume (MTV), total lesion glycolysis (TLG), @entity413 corrected SUV (SUVgluc), and @entity413 corrected TLG (TLGgluc) were measured for the @entity5 . Cut-off values for the metabolic parameters were calculated by ROC curve analysis, and used to dichotomize the @entity1 groups. The @entity1349 ( @entity1349 ) was calculated and compared using the Cox proportional hazard regression analysis. RESULTS: The median duration of follow-up period was 5.4  months (interquartile range: 1.45   15.45). FDG PET/CT showed higher sensitivity than conventional imaging modalities in detection of regional node involvement (74.5  % vs. 61.8  %, p   =   0.013). In six @entity1 , distant @entity3 was identified only by FDG PET/CT. The mean SUVmax, SUVpeak, SUVmean, MTV, and TLG for the @entity5 were 8.2        3.1, 6.8        2.5, 4.0        0.8, 192.7        360.5  cm(3), and 823.7        1615.4, respectively. @entity1 with higher (>= 7.3, HR: 4.280, p   =   0.001), higher SUVpeak (>= 6.5, HR: 2.333, p   =   0.020), higher SUVmean (>= 3.9, HR: 2.799, p   =   0.004), higher SUVgluc (>= 8.1, HR: 2.648, p   =   0.012), and higher TLGgluc (>= 431.6, HR: 2.186, p   =   0.030) showed significantly shorter survival time. By multivariate study, operability was an independent prognostic factor for longer survival (HR: 4.113, p   =   0.005). CONCLUSION: FDG PET/CT is an important diagnostic imaging tool in the nodal staging and detection of distant @entity3 in @entity1419 @entity1 . Metabolic parameters may have a significant role as prognostic factors in @entity1 with @entity1419 .

The Role of F-18 FDG PET/CT in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumor', 'malignancy'] @entity1419 :: ('MESH:C535533', 'Disease') :: ['ICC', 'intrahepatic cholangiocarcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival time']
@entity1419 :: (MESH:C535533,Disease) :: ['Intrahepatic Cholangiocarcinoma']
