PURPOSE: In this study, we aimed to evaluate the role of @entity4580 in the treatment of acute infraorbital space infection. MATERIALS AND METHODS: Sixty @entity1 (39 @entity1 and 21 @entity1 ; age range, 18 to 47 years) who had acute infraorbital space infection with @entity158 were included in the study. After initial surgical therapy, @entity1 were randomly allocated to receive either 500 mg @entity4580 once daily for 3 days, 250 mg @entity2929 stearate every 6 hours for 3 days, or no antibiotic. @entity1 were assessed at the time of admission and after 1, 2, 3, and 7 days. @entity158 , swelling, @entity3799 , and sublingual temperature were assessed at each visit. Data were collected, and all groups were compared for differences in @entity158 and swelling using the Mann-Whitney U test and for differences in @entity3329 and sublingual temperature using Fisher's exact test. RESULTS: At the time of admission, no 2 groups were statistically different at the.05 level in relation to age, gender, and presenting clinical signs or symptoms. At days 2 and 3, @entity1 who received @entity4580 had a significant reduction in @entity158 (P =.002 and P =.02, respectively) and swelling (P =.001 and P =.013, respectively) compared with those who received no antibiotic. At day 3, @entity1 who received @entity2929 had a significant reduction in @entity158 (P =.03) and swelling (P =.046) compared with those who received no antibiotic. In a comparison of the @entity1 who received @entity4580 with those who received @entity2929 , there was no significant difference (P >.05) in the reduction of @entity158 at any time of the study. However, at day 2, @entity1 who received @entity4580 had a significantly greater reduction in swelling (P =.002) than those who received @entity2929 . In relation to the percentage of the @entity1 with @entity3799 and raised sublingual temperature (>37.2 degrees C), no 2 groups were statistically different at any time of the study. After 3 days of treatment, @entity1 who received the antibiotics were clinically improved, and all @entity1 (n = 60 @entity1 ) reviewed after 7 days had resolution of their clinical signs and symptoms. CONCLUSION: This study emphasizes the importance of surgical drainage and proves that both @entity4580 and @entity2929 are effective adjunctive treatments in the therapy of relatively mild @entity281 .

The efficacy of XXXX in the treatment of acute infraorbital space infection.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['lymphadenopathy'] @entity2929 :: ('MESH:D004917', 'Chemical') :: ['erythromycin'] @entity4580 :: ('MESH:D017963', 'Chemical') :: ['azithromycin'] @entity281 :: ('MESH:D007239', 'Disease') :: ['odontogenic orofacial infections'] @entity3799 :: ('MESH:D002575', 'Disease') :: ['cervical lymphadenopathy'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain, swelling, and general malaise', 'pain']
@entity4580 :: (MESH:D017963,Chemical) :: ['azithromycin']
