PURPOSE: To review the clinical, neurophysiologic features and surgical outcomes in @entity1 with @entity1313 and chronic intractable @entity410 . METHODS: Medical records of @entity1 with intractable @entity302 who underwent resection or stereotactic biopsy of @entity1313 (confirmed by surgical pathology) seen between 1985 and 1999 at Yale University School of Medicine @entity302 Center were reviewed for age at diagnosis, age at onset of @entity410 , delay between @entity410 onset and @entity5 diagnosis, types and frequencies of @entity410 , EEG results, use of anticonvulsants, extent of surgery, pathological diagnosis, and @entity5 recurrence. RESULTS: Thirty-seven @entity1 were included. Mean age at @entity410 onset was 31.6 years, and at @entity5 diagnosis was 36.2 years. Mean duration between onset of @entity410 and @entity5 diagnosis was 6.1 years. Seventeen @entity1 had auras. @entity410 frequency averaged 7.6 @entity410 per week, with 58% of @entity1 having more than one @entity410 type. All patients used anticonvulsants, with 90% eventually using polytherapy. All @entity1 eventually underwent at least one surgical procedure. Only 13 (35.1%) @entity1 were class I. Twelve (32.4%) @entity1 were class II, seven (18.9%) class III, and five (13.5%) class IV. No statistically significant differences were seen between good and poor long-term @entity410 outcome in relation to specific @entity5 pathology, @entity410 types, or type of resection. CONCLUSIONS: Long-term surgical outcomes in @entity4940 are more favorable than those in nontumoral @entity4940 (65% class I or II) and less favorable than those in other @entity5 (overall, 70% class I). Frontal location of @entity1313 may predict a less favorable long-term @entity302 prognosis than @entity5 in general, an observation for which several explanations are proposed.

XXXX : clinical, neurophysiologic features and predictors of surgical outcome.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures', 'Seizure'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['frontal lobe tumor', 'frontal lobe tumors', 'intracranial neoplasm'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumoral epilepsy'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy', 'Epilepsy'] @entity4940 :: ('MESH:D017034', 'Disease') :: ['intractable frontal lobe epilepsy', 'tumoral frontal lobe epilepsy']
@entity4940 :: (MESH:D017034,Disease) :: ['Frontal lobe tumoral epilepsy']
