UNASSIGNED: @entity5 , occurring in advanced stages of @entity5 , is linked with poor prognosis and can cause invalidating symptoms. Physiopathological mechanisms of @entity843 formation are complex and have yet to be fully elucidated. In most cases, @entity843 is due to @entity298 in which vascular permeability is enhanced by @entity7 production while lymphatic drainage decreases. Ascites can also be secondary to portal @entity101 , for example in case of multiple liver @entity3 , or due to @entity3885 . While paracentesis and diuretics are commonly used, their efficiency has never been compared in a randomized controlled study. Paracentesis brings immediate but temporary relief in over 90% of cases, and implies multiple hospitalizations. Literature reports @entity843 control by @entity1369 alone or in association with @entity1483 . But, available data is controversial, and there is no predictive factor to identify @entity1 that respond to diuretic treatment. The indication of diuretic treatment is left to the appreciation of physicians. Existing recommendations are old, and practices influenced by results obtained in non-neoplastic @entity843 . Additional evidences are required before guidelines can be established for the palliative management of @entity5 .

[Supportive care for XXXX in palliative phase: Place of paracentesis and diuretics].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1369 :: ('MESH:D000450', 'Chemical') :: ['aldosterone'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity7 :: ('7422', 'Gene') :: ['VEGF'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant ascites', 'cancer', 'Malignant ascites'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity1483 :: ('MESH:D005665', 'Chemical') :: ['furosemide'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['lymphatic obstruction'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity298 :: ('MESH:D010538', 'Disease') :: ['peritoneal carcinomatosis']
@entity5 :: (MESH:D009369,Disease) :: ['malignant ascites']
