OBJECTIVE: The aim of this study was to investigate software accuracy and influence of body mass index on image quality of Lunar iDXA (Lunar, Madison, WI, USA; software enCORE 12.0) in @entity174 (VFs) assessment. MATERIALS AND METHODS: We enrolled 65 normal or overweight @entity1 (group 1) and 64 @entity28 @entity1 (group 2) with indication for morphometric evaluation of the spine. @entity1 underwent iDXA, with scans performed in the standard manner by an expert technologist. Lateral images of the spine were subsequently evaluated by a musculoskeletal radiologist as the gold standard. Our analysis considered five points: vertebral bodies missed or not assessable or wrongly labeled on T4-L4 segment, diagnostic performance of the automatic morphometric point-positioning system in the detection of VFs, upgrading and downgrading of @entity174 , radiologist intervention rate, and BMI influence. RESULTS: In group 1, 57/845 (6.7%) vertebral bodies and 34/832 (4.1%) in group 2 were not assessable-the upper thoracic spine. enCORE failed to recognize vertebral levels in 5.4% of the @entity1 (7.7% in group 1 vs. 3.1% in group 2). On a lesion-based analysis sensitivity, specificity and accuracy of the software were 81.4, 93.8, and 93.1% in group 1 and 69.1, 88.3, and 86.7% in group 2, respectively. For 52.7% of the vertebrae in group 1 (51/8 upgraded/downgraded) and 70.0% in group 2 (96/26 upgraded/downgraded), a point correction was necessary and this changed the diagnosis respectively in 29.2 and 50.0% of the @entity1 . Differences in diagnostic performance and point correction rate were significantly different between the two groups; however, BMI did not significantly affect vertebral level labeling and was correlated with a better visualization of the whole T4-L4 spine segment. CONCLUSIONS: This study provides new and interesting information about the accuracy, reliability, and imaging quality provided by iDXA in the assessment of VFs.

New dual-energy X-ray absorptiometry equipment in the assessment of vertebral XXXX : technical limits and software accuracy.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures', 'vertebral fracture']
@entity174 :: (MESH:D050723,Disease) :: ['fractures']
