@entity1031 events are a known complication in neurosurgical @entity1 . There is evidence to suggest that a @entity49 state may develop perioperatively. Thrombelastograph (TEG) coagulation analysis is a reliable method of evaluating @entity49 . We evaluated coagulation by using TEG data in pediatric neurosurgical @entity1 undergoing craniotomy to determine whether a @entity49 state develops intraoperatively or postoperatively. Thirty @entity1 undergoing craniotomy for removal of a @entity5 or @entity410 focus were studied. Blood was analyzed with TEG) data by using native and celite techniques, at three time points for each @entity1 : preoperatively after induction of anesthesia; intraoperatively during closure of the dura; and on the first postoperative day. Compared with preoperative indices, closing and postoperative celite TEG values were indicative of @entity49 with shortened coagulation time values (P < 0.001), prolonged alpha angle divergence values (P < 0.001), and above-normal TEG coagulation indices (P < or = 0.002). Reaction time values were shortened, and maximal amplitude of clot strength values were prolonged but did not reach statistical significance. Hypercoagulation develops early after resection of brain tissue in pediatric neurosurgical @entity1 as assessed by using TEG data. Further studies are needed to determine the clinical significance of this @entity49 state. IMPLICATIONS: @entity49 in postoperative neurosurgical @entity1 has been demonstrated in the adult population, but few studies have dealt with the pediatric population. We found that @entity1 undergoing craniotomy for focal resection, lobectomy, and hemispherectomy are @entity49 as detected by thrombelastograph coagulation analysis. Further studies are needed to determine whether this is clinically significant.

Hemostatic changes in pediatric neurosurgical XXXX as evaluated by thrombelastograph.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity49 :: ('MESH:D019851', 'Disease') :: ['hypercoagulable', 'Hypercoagulability', 'hypercoagulability'] @entity1031 :: ('MESH:D013923', 'Disease') :: ['Thromboembolic']
@entity1 :: (9606,Species) :: ['patients']
