PURPOSE: The aim of this study was to evaluate characteristics of @entity463 multiforme, effectiveness of treatment modalities, and detect factors related to outcome. METHODS: A detailed analysis was performed on a series of 15 @entity1 treated between 2000 and 2013, based on their clinical, radiologic, pathologic, treatment, and follow-up data. RESULTS: Median survival time of @entity1 with @entity463 was 13.5  months. One- and 2-year overall survival probabilities were 66.7 and 20  %, respectively. There were no significant differences in survival based on @entity1 ' gender, age, disease presentation with or without @entity302 , signs/symptoms of @entity428 , or @entity5 location. The presence of @entity51 initially, as well as prior to radiotherapy, which was quantified by neurologic function score (NFS), had an impact on overall survival. @entity1 with NFS 0 lived longer compared to others (p   =   0.001). Survival of @entity1 that underwent gross total resection was longer than that of @entity1 that underwent subtotal resection (p   =   0.030). Mean survival time of @entity1 with gross total resection was 73.5  months, compared to 13  months in @entity1 with subtotal resection. There was no significant correlation between outcome and type of radiotherapy. In four @entity1 with gigantocellular @entity463 , we found no evidence of a better prognosis. Two long-term survivors were recorded. Both of them underwent gross total resection and were assigned a NFS 0. CONCLUSIONS: Gross total resection is essential for longer overall survival among pediatric @entity1 with @entity463 and offers a possibility for long-term survival. Severity of neurologic symptoms quantified by NFS can be considered as a potential predictor of outcome.

XXXX : a single institution experience.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'Children'] @entity428 :: ('MESH:D019586', 'Disease') :: ['increased intracranial pressure'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficit'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epileptic seizures'] @entity463 :: ('MESH:D005909', 'Disease') :: ['childhood glioblastoma', 'glioblastoma']
@entity463 :: (MESH:D005909,Disease) :: ['Pediatric glioblastoma']
