Metal ions including @entity219 have the ability to influence @entity2193 . However, there is a paucity of data regarding reductions in demineralisation effected by @entity219 ions ( @entity8862 ) in the literature. Therefore the aim was to measure the effects of @entity219 ion concentration ([ @entity8862 ]) on the real-time in vitro demineralisation of enamel, during exposure to caries-simulating conditions, using scanning microradiography (SMR). @entity1 enamel blocks were fixed in SMR environmental cells, through which acidic solutions (0.1 M @entity1543 , pH 4.0) were circulated for periods of 50 h. SMR was used to quantitatively measure continuous mineral mass loss. Subsequently, the effects of sequentially increasing [ @entity8862 ] (0.1-3,565 ppm) in the acidic solutions were measured on the rate of @entity2193 . This study demonstrated that @entity8862 even at low concentrations significantly reduces @entity2193 . There was a log-linear relationship between the mean percentage @entity353 and increasing [ @entity8862 ] up to 3,565 ppm, i.e. the change in the overall percentage @entity353 was greater at lower concentrations than at higher concentrations, with 60% reduction at 36 ppm increasing to 90% at 3,565 ppm. In conclusion, SMR demonstrated the ability of @entity8862 to reduce the rate of @entity2193 under real-time in vitro acid conditions simulating dental caries. The results suggest that @entity8862 in the oral fluids could protect against @entity2193 during an acidic challenge. The log-linear relationship between [ @entity8862 ] and demineralisation suggests that the reduction in enamel dissolution is limited by the saturation of surface sites on the enamel surface.

Inhibitory Effects of XXXX Ions on Enamel Demineralisation Kinetics in vitro.

@entity8862 :: ('CHEBI:37256', 'Chemical') :: ['Zn2+'] @entity1 :: ('9606', 'Species') :: ['Human'] @entity353 :: ('MESH:D015431', 'Disease') :: ['reduction in demineralisation'] @entity219 :: ('MESH:D015032', 'Chemical') :: ['zinc'] @entity2193 :: ('MESH:D003744', 'Disease') :: ['enamel demineralisation'] @entity1543 :: ('MESH:D019342', 'Chemical') :: ['acetic acid']
@entity219 :: (MESH:D015032,Chemical) :: ['Zinc']
