UNASSIGNED: The influence of race on quality of anticoagulation control is not well described. We examined the association between race, international normalized ratio (INR) monitoring intensity, and INR control in @entity1229 -treated @entity1 with @entity955 ( @entity955 ). Using data from the @entity283 ( @entity283 ), we performed a retrospective cohort study of 184,161 @entity1 with a new diagnosis of @entity955 /flutter from 2004 to 2012 who received any @entity283 prescription within 90  days of diagnosis. The primary predictor was race, ascertained from multiple @entity283 and linked Medicare demographic files. The primary outcome was first-year and long-term time in therapeutic range (TTR) of INR 2.0 to 3.0. Secondary outcomes were INR monitoring intensity and @entity1229 persistence. Of the 116,021 @entity1 who received @entity1229 in the cohort, INR monitoring intensity was similar across racial groups. However, TTR was lowest in blacks and highest in whites (first year 0.49    0.23 vs 0.57    0.21, p <0.001; long term 0.52    0.20 vs 0.59    0.18, p <0.001); 64% of whites and 49% of blacks had long-term TTR >55% (p <0.001). After adjusting for site and @entity1 -level covariates, black race was associated with lower first-year and long-term TTRs (4.2% and 4.1% below the conditional mean, relative to whites; p <0.0001 for both). One-year @entity1229 persistence was slightly lower in blacks compared to whites (58% vs 60%, p <0.0001). In conclusion, in @entity1 with @entity955 anticoagulated with @entity1229 , differences in INR control are most evident among blacks, underscoring the need to determine if other types of intensive management or @entity1229 alternatives may be necessary to improve anticoagulation among vulnerable @entity955 populations.

Racial Differences in Quality of Anticoagulation Therapy for XXXX (from the TREAT- @entity955 Study).

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation', 'AF'] @entity283 :: ('OMIM:603663', 'Disease') :: ['Veterans Health Administration', 'VHA'] @entity1229 :: ('MESH:D014859', 'Chemical') :: ['warfarin']
@entity955 :: (MESH:D001281,Disease) :: ['Atrial Fibrillation']
