@entity235 were given infusions of @entity1063 and subsequent additional infusions of @entity1169 and @entity1670 over a 4-hr period. Under different physiological conditions, alpha-lipoproteins of three different electrophoretic mobilities were identified by means of paper electrophoresis; they were designated alpha-lipoproteins X, Y, and Z. During @entity1063 infusion, alpha-lipoprotein Y fell from 45% (of all lipoproteins) to 14%. There was a reciprocal rise in alpha-lipoprotein Z. On the other hand, alpha-lipoprotein X was not significantly changed. There was evidence that alpha-lipoprotein Y was progressively transformed into alpha-lipoprotein Z by increasing plasma @entity6334 concentrations. The percentages of both alpha-lipoproteins Y and Z returned to original values after the @entity235 were given either @entity1670 or @entity1169 . The alterations in the alpha-lipoprotein peaks Y and Z were rapid, being noted within 5 min of change in plasma @entity6334 concentration. However, there appeared to be a threshold of plasma @entity6334 concentration of 1200 micro Eq/liter, below which no changes in alpha-lipoproteins were noted. It was concluded that alpha-lipoprotein Y is rapidly, progressively, but reversibly transformed into alpha-lipoprotein Z by binding to plasma @entity6334 above a threshold level of 1200 micro Eq/liter. However, alpha-lipoprotein X does not appear to be involved in the binding of plasma @entity6334 .

Effect of free fatty acid mobilization on the electrophoretic mobility of alpha-lipoproteins in the XXXX .

@entity1169 :: ('MESH:D011433', 'Chemical') :: ['propranolol'] @entity235 :: ('9615', 'Species') :: ['Dogs', 'dogs'] @entity1670 :: ('MESH:D009525', 'Chemical') :: ['nicotinic acid'] @entity6334 :: ('CHEBI:42638', 'Chemical') :: ['FFA'] @entity1063 :: ('MESH:D009638', 'Chemical') :: ['norepinephrine']
@entity235 :: (9615,Species) :: ['dog']
