BACKGROUND: @entity177 ( @entity177 ), defined as need for re-intubation within 24-72  h, is multifactorial. Factors predicting @entity177 in adults generally are not useful in @entity1 . OBJECTIVE: To determine the factors associated with @entity177 and to facilitate prediction of @entity177 in mechanically ventilated @entity1 and @entity1 less than 12  years of age. MATERIAL AND  METHODS: Design Prospective cohort study. Setting PICU and NICU of a multispecialty tertiary care institute. @entity1 All consecutive newborns, @entity1 and @entity1 , who remained on the ventilator for more than 12  h, were included. @entity1 with @entity4094 , complex anatomic @entity600 , accidental extubation, tracheostomy or @entity204 before extubation were excluded. Methods The pre-extubation clinical, laboratory and ventilatory parameters were collected for 92 cases over a one and half year period. The @entity177 rate was calculated for each variable using STATA 9. All the treating physicians were blinded to the data collection procedure. MEASUREMENTS AND RESULTS: Demographics were comparable between the extubation success and @entity177 groups. @entity1576 was the main cause requiring ventilation (46.74  %, 95  % CI 0.37-0.57) as well as @entity177 (30.23  %, 95  % CI 0.08-0.23). 76.92  % (95  % CI 0.58-0.89) of @entity1 that failed extubation had alterations in respiratory effort, 38.46  % (95  % CI 0.22-0.57) each had either poor or increased respiratory effort. Poor cough reflex (p  =  0.001), thick endotracheal secretions (p  =  0.02), failed spontaneous breathing trial (SBT) (p  =  0.001) and higher rapid shallow breathing index (RSBI) (p  =  0.001) were found to be associated with @entity177 . CONCLUSIONS: Paediatric @entity177 is multifactorial. Increased or poor respiratory effort and failed SBT are potential factors in deciding re-intubation. Increased RSBI, poor cough reflex and thick.

Prediction of extubation failure in newborns, @entity1 and XXXX : brief report of a prospective (blinded) cohort study at a tertiary care paediatric centre in India.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'infants'] @entity4094 :: ('MESH:D009468', 'Disease') :: ['upper airway obstruction, neuromuscular disorders'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity177 :: ('MESH:D051437', 'Disease') :: ['EF', 'Extubation failure'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['Respiratory failure'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1 :: (9606,Species) :: ['children']
