STUDY OBJECTIVES: The aim of this study was to measure inspiratory pressure-generating capacity in @entity1 presenting with @entity697 , as it has been suggested that @entity121 may contribute to breathlessness and @entity1576 . DESIGN: Descriptive study. SETTING: Emergency departments of two inner-city hospitals. @entity1 : Fifty-one @entity1 with @entity697 , and 45 @entity1 without @entity1576 who served as control subjects. MEASUREMENTS AND RESULTS: Maximum inspiratory pressure-generating capacity was measured soon after presentation by the sniff nasal inspiratory pressure (SNIP) method. The mean (SD) SNIP was 110 cm @entity2507 (23 cm @entity2507 ) in @entity1 with @entity565 (mean for control subjects, 126 cm @entity2507 [25 cm @entity2507 ]; p < 0.05) and 80 cm @entity2507 [24 cm @entity2507 ] in @entity1 with @entity565 (mean for control subjects, 105 cm @entity2507 (26 cm @entity2507 ); p < 0.01). In a second study of simultaneous SNIP and intrathoracic pressure measurements in a group of @entity1 with @entity697 (n = 10) and control subjects (n = 11), the effect of airways obstruction on SNIP was assessed. The measurement of sniff esophageal pressure was more negative than SNIP by approximately 16% in @entity748 @entity1 and by 4% in control subjects. Taking account of the likely effect of airways obstruction on SNIP, the reduction in inspiratory pressure-generating capacity that was observed in these @entity1 with moderately severe @entity697 was minor and was consistent with the modest hyperinflation observed. CONCLUSIONS: This study did not find evidence of @entity425 or @entity1295 in @entity1 with moderately severe @entity697 presenting to the emergency department.

Inspiratory muscle strength in XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'PATIENTS', 'men'] @entity748 :: ('MESH:D013224', 'Disease') :: ['asthmatic'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute asthma'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity425 :: ('MESH:D018908', 'Disease') :: ['inspiratory muscle weakness'] @entity2507 :: ('CHEBI:33813', 'Chemical') :: ['H(2)O'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory disease', 'acute respiratory failure'] @entity121 :: ('MESH:D009135', 'Disease') :: ['inspiratory muscle fatigue']
@entity697 :: (MESH:D000208,Disease) :: ['acute asthma']
