AEROSOL THERAPY HAS THREE PRINCIPAL OBJECTIVES: Mobilization of bronchial secretions, relief of @entity5143 and topical chemotherapy. It has become an important tool in the treatment of @entity66 . The equipment for inhalation therapy, however, should be adequate. Both large-capacity and small-capacity nebulizers must be available, and they must be the kind that will produce a mist with most of its particles only 0.5 to 2.5 micra in diameter. These nebulizers may be used alone or in conjunction with a variety of appliances that will deliver the aerosols to the respiratory tract. The use of humidifying agents as aerosols is extremely helpful in @entity1 with retained bronchopulmonary secretions. In some @entity1 who have particularly thick or gelatinous secretions and in @entity1 with @entity1577 , ordinary water or saline solution is often not enough. @entity4372 saline may be of value in these cases, and it is suggested that half-molar (2.9 per cent) saline be administered in 10 per cent @entity2771 . In these cases, preparations containing detergents (tyloxypal) or other preparations containing enzymes (desoxyribonuclease or trypsin) may be given by the aerosol technique, with care not to cause @entity146 . The bronchodilator aerosol agents are of proved benefit in the treatment of @entity74 and are indicated in most cases of @entity565 and in those cases of @entity2415 in which there is definite evidence of associated @entity5143 . The value of the aerosol method of administering chemotherapeutic and antibiotic drugs has probably been overrated, and it is suspected that much of the benefit previously attributed to the therapeutic agent was actually a result of humidification and liquefaction.

Aerosol therapy in XXXX . A critical evaluation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2771 :: ('MESH:D019946', 'Chemical') :: ['propylene glycol'] @entity66 :: ('MESH:D004194', 'Disease') :: ['bronchopulmonary diseases'] @entity146 :: ('MESH:D001523', 'Disease') :: ['irritation'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity2415 :: ('MESH:D004646', 'Disease') :: ['emphysema'] @entity74 :: ('MESH:D030342', 'Disease') :: ['bronchospastic disorders'] @entity4372 :: ('MESH:D009122', 'Disease') :: ['Hypertonic'] @entity5143 :: ('MESH:D001986', 'Disease') :: ['bronchospasm'] @entity1577 :: ('MESH:D003550', 'Disease') :: ['mucoviscidosis']
@entity66 :: (MESH:D004194,Disease) :: ['bronchopulmonary disease']
