PURPOSE: The purpose of this article is to provide a review of the existing literature for the comanagement of @entity308 and @entity28 in the pediatric population. METHODS: A review of the current literature was conducted using EBSCOhost and EMBASE to identify evidence and recommendations for the comanagement of @entity308 and @entity28 among @entity1 and adolescents (aged 2-18 years). Additional search criteria included peer-reviewed, English language-only full-text articles published before August 2015. FINDINGS: Multiple factors contribute to and influence the interplay of @entity28 and @entity308 in the pediatric population. These 2 chronic conditions are affected by multiple factors, including the roles of the family, school, health care practitioners, and access to health care. In addition, there are no formal recommendations for the treatment of @entity308 in the setting of @entity28 for pediatric or adult populations, and there is only medication approved by the Food and Drug Administration ( @entity350 ) for the treatment of @entity28 in the adolescent population. Bariatric surgery may play a role in some adolescents, but larger and long-term clinical studies with the use of therapeutic agents in conjunction with lifestyle modification need to be conducted to support this. IMPLICATIONS: The interrelatedness of these 2 separate diseases is not well understood; the presence of 1 of the diseases clearly contributes to the manifestation of the other and likely to the ability to treat the other disease. Current focus is on modifying behavior to decrease weight. Weight loss is associated with improvement in depressive symptoms but may not be adequate to treat @entity308 .

Comanagement of Pediatric XXXX : A Clear Need for Evidence.

@entity1 :: ('9606', 'Species') :: ['children'] @entity350 :: ('MESH:C055122', 'Chemical') :: ['orlistat'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity']
@entity308 :: (MESH:D003866,Disease) :: ['Depression and Obesity']
