BACKGROUND: Marital status, income, and education might influence the risk of esophageal and @entity356 , but the literature is limited. A large study addressing subtypes of these @entity5 was used to clarify these associations. METHODS: A nationwide, Swedish population-based cohort study from 1991 to 2010 included individuals who were 50 years old or older. Data on exposures, covariates, and outcomes were obtained from well-maintained registers. Four @entity5 subtypes were analyzed in combination and separately: @entity420 , @entity1721 , @entity420 , and noncardia @entity356 . Poisson regression was used to estimate incidence rate ratios (IRRs) and 95% confidence intervals (CIs). Analyses were stratified by sex and adjusted for confounders. RESULTS: Among 4,734,227 @entity1 (60,634,007 @entity1 -years), 24,095 developed esophageal or @entity356 . In comparison with individuals in a long marriage, increased IRRs were found among @entity1 who were in a shorter marriage or were never married, remarried, divorced, or widowed. These associations were indicated for each @entity5 subtype but were generally stronger for @entity1721 . Higher education and income were associated with decreased IRRs in a seemingly dose-response manner and similarly for each subtype. In comparison with the completion of only primary school, higher tertiary education rendered an @entity12623 of 0.64 (95% CI, 0.60-0.69) for @entity1 and an @entity12623 of 0.68 (95% CI, 0.61-0.75) for @entity1 . Comparing @entity1 in the highest and lowest income brackets (highest 20% vs lowest 20%) revealed an @entity12623 of 0.74 (95% CI, 0.70-0.79) for @entity1 and an @entity12623 of 0.83 (95% CI, 0.76-0.91) for @entity1 . CONCLUSIONS: Divorce, widowhood, living alone, low educational attainment, and low income increase the risk of each subtype of esophageal and @entity356 . These associations require attention when high-risk individuals are being identified. @entity5 2015.    2015 American @entity5 Society.

Marital status, education, and income in relation to the risk of esophageal and XXXX by histological type and site.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'person', 'men'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors', 'Cancer', 'esophagogastric tumor'] @entity1721 :: ('MESH:C562729', 'Disease') :: ['esophageal squamous cell carcinoma'] @entity12623 :: ('3645', 'Gene') :: ['IRR'] @entity420 :: ('MESH:D000230', 'Disease') :: ['cardia adenocarcinoma', 'esophageal adenocarcinoma'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'gastric adenocarcinoma']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
