PURPOSE: To analyze the priority of morphological and functional defects in @entity726 . METHODS: Nine-hundred seventy-three eyes of 973 subjects were examined with Heidelberg retinal tomograph (HRT II) and Octopus 311 perimeter (TOP strategy). These included 72 controls (C), 659 early and suspect open @entity726 (ESG) with perimetric @entity154 ( @entity154 ) lower than 6 dB, and 242 confirmed moderate and @entity726 ( @entity726 ) with perimetric @entity154 >or=6 dB. RESULTS: I. (Control group): Age was significantly correlated with @entity2915 ( @entity2915 ) (r=0.50, p<0.00001) and nasal cup shape measure (r=0.33, p=0.005). II. (C and ESG groups): For 95.8% specificity, the best sensitivity was obtained with square root of loss variance (sLV) (ROC area=69.7%, sensitivity=33.7%) and maximum contour elevation (ROC area=69.6%, sensitivity=29.0%). Maximum contour elevation and sLV coincided in diagnosis in 12.4% of cases. An equation using 64 HRT II indices predicted @entity2915 with a standard error of estimate (SEE) of 1.87 dB (r=0.67, p<0.00001) and @entity154 (SEE=1.88 dB, r=0.47, p<0.00001). III. (All cases): RB discriminant function value was the best HRT II index to estimate @entity2915 values (SEE=5.4 dB, r=0.52, p<0.0001), @entity154 (SEE=5.2 dB, r=0.50, p<0.0001), sLV (SEE=1.9 dB, r=0.41, p<0.0001) and Number of Pathological Points (NPP; SEE=21.3 dB, r=0.49, p<0.0001). Sector correlation of the optic nerve and visual field was high (maximum r=0.66) in cases with superior @entity227 and low in the rest of cases. More than 95% of cases with established @entity726 had abnormal sLV, but <60% had abnormal optic disc indices. DISCUSSION: Perimetry reveals age-related defects slightly more than HRT II. HRT II indices correlated better with @entity2915 than with @entity154 , probably because none of them was age corrected. Good correlation between anatomical and functional data in C and ESG, and sensitivity results indicated small differences in early development between both methods. Perimetry identifies defects more clearly than structural measures in established @entity726 .

Optic disc tomography and perimetry in controls, @entity726 suspects, and early and XXXX .

@entity154 :: ('MESH:D000013', 'Disease') :: ['MD', 'mean defect'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual field defects'] @entity2915 :: ('MESH:D006948', 'Disease') :: ['mean sensitivity', 'MS'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma', 'advanced glaucomas', 'AG', 'angle glaucoma']
@entity726 :: (MESH:D005901,Disease) :: ['established glaucomas']
