CONTEXT: Studies suggest that appropriate nutritional modifications can improve the natural conception rate of infertile couples. OBJECTIVES: The purpose of this study was to review the @entity1 trials that investigated the relation between nutrition and @entity4810 . DATA SOURCES: A comprehensive systematic review of published @entity1 studies was carried out by searching scientific databases. Article selection was carried out in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The American Dietetic Association Research Design and Implementation Checklist was also used for quality assessment. DATA EXTRACTION: A total of 502 articles were identified, of which 23 studies met the inclusion criteria. DATA SYNTHESIS: Results indicated that a healthy diet improves at least one measure of semen quality, while diets high in lipophilic foods, soy @entity6400 , and sweets lower semen quality. CONCLUSION: The role of daily nutrient exposure and dietary quality needs to be highlighted in @entity4810 . Mechanistic studies addressing the responsible underlying mechanisms of action of dietary modifications are highly warranted. Systematic Review Registration: PROSPERO 2013: CRD42013005953. Available at: http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42013005953.

Nutritional modifications in XXXX : a systematic review covering 2 decades.

@entity1 :: ('9606', 'Species') :: ['human'] @entity6400 :: ('MESH:D007529', 'Chemical') :: ['isoflavones'] @entity4810 :: ('MESH:D007248', 'Disease') :: ['male infertility']
@entity4810 :: (MESH:D007248,Disease) :: ['male infertility']
