OBJECTIVES: To prospectively evaluate the predictive value of cerebral perfusion-computerized tomography (CTP) parameters variation between day0 and day4 after @entity510 ( @entity510 ). METHODS: Mean transit time (MTT) and cerebral blood flow (CBF) values were compared between @entity1 with delayed @entity2806 ( @entity1585 + group) and @entity1 without @entity1585 ( @entity1585 ) for previously published optimal cutoff values and for variations of MTT (  MTT) and of CBF (  CBF) values between day0 and day4. @entity1585 + was defined as a @entity385 on 3-months follow-up MRI. RESULTS: Among 47 included @entity1 , 10 suffered @entity1585 +. Published optimal cutoff values did not predict @entity1585 , either at day0 or at day4. Conversely,   MTT and   CBF significantly differed between the @entity1585 + and @entity1585 - groups, with optimal   MTT and   CBF values of 0.91  seconds (83.9  % sensitivity, 79.5  % specificity, AUC 0.84) and -7.6  mL/100  g/min (100  % sensitivity, 71.4  % specificity, AUC 0.86), respectively. In multivariate analysis,   CBF (OR   =   1.91, IC95% 1.13-3.23 per each 20  % decrease of   CBF) and   MTT values (OR   =   14.70, IC95% 4.85-44.52 per each 20  % increase of   MTT) were independent predictors of @entity1585 . CONCLUSIONS: Assessment of MTT and CBF value variations between day0 and day4 may serve as an early imaging surrogate for prediction of @entity1585 in @entity510 . KEY POINTS:     CT perfusion values are an imaging surrogate for prediction of @entity1585 .     Early variations (day0-day4) after @entity510 predicted @entity1585 .     A CBF decrease of 7.6  mL/min/100  g predicted @entity1585 with 100   % sensitivity.     An MTT increase of 0.91  seconds predicted @entity1585 with 83.9   % sensitivity.     @entity1585 risk multiplied by 2 per 20   %   CBF decrease and by 15 per 20   %   MTT increase.

Early quantitative CT perfusion parameters variation for prediction of delayed XXXX following @entity510 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['cerebral ischemia'] @entity510 :: ('MESH:D013345', 'Disease') :: ['aneurysmal subarachnoid haemorrhage', 'aSAH'] @entity1585 :: ('MESH:D065703', 'Disease') :: ['DCI- group', 'DCI'] @entity385 :: ('MESH:D002544', 'Disease') :: ['cerebral infarction']
@entity2806 :: (MESH:D002545,Disease) :: ['cerebral ischemia']
