Abstract Objective: Percutaneous correction of @entity339 ( @entity339 ) by MitraClip (Abbot Vascular, Abbot Park, Illinois, USA) trans-catheter procedure ( @entity15928 ) may represent a treatment for an unmet need in @entity712 ( @entity712 ), but with a largely unclear economic impact. Research design and methods: This study estimated the economic impact of the @entity15928 in common practice using the disease-related group (DRG) billing system, duration and average cost per day of hospitalization as main drivers. Life expectancy was estimated based on the Seattle @entity712 Model. Quality-of-life was derived by standard questionnaires to compute quality-adjusted year-life costs. Results: Over 5535 discharges between 2012-2013, @entity712 as DRG 127 was the main diagnosis in 20%, yielding a reimbursement of    3052.00/case; among the DRG 127, @entity339 by ICD-9 coding was found in 12%. Duration of hospitalization was longer for DRG 127 with than without @entity339 (9 vs 8 days, p   <   0.05). @entity712 in-hospital management generated most frequently deficit, in particular in the presence of @entity339 , due to the high costs of hospitalization, higher than reimbursement. @entity15928 to treat @entity339 allowed DRG 104-related reimbursement of    24,675.00. In a cohort of 34 @entity712 @entity1 treated for @entity339 by @entity15928 , the global budget consumption was 2-fold higher compared to that simulated for those cases medically managed at 2-year follow-up. Extrapolated cost per quality-adjusted-life-years (QALY) for @entity15928 at year-2 follow-up was       16,300. Conclusions: Based on DRG and hospitalization costing estimates, @entity15928 might be cost-effective in selected @entity712 @entity1 with @entity339 suitable for such a specific treatment, granted that those @entity1 have a clinical profile predicting high likelihood of post-procedural clinical stability in sufficiently long follow-up.

Impact of DRG billing system on health budget consumption in percutaneous treatment of mitral valve regurgitation in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity15928 :: ('4490', 'Gene') :: ['MTP'] @entity712 :: ('MESH:D006333', 'Disease') :: ['HF', 'Heart Failure', 'heart failure'] @entity339 :: ('MESH:D008944', 'Disease') :: ['MR', 'mitral regurgitation']
@entity712 :: (MESH:D006333,Disease) :: ['heart failure']
