BACKGROUND: The risk for development of certain @entity5 after transplantation is well known. Especially in @entity272 , rapid progression is described. The aim of this study is to evaluate the progress of Barrett's mucosa to @entity7145 after liver transplantation. METHODS: Between 2000 and 2009, 895 @entity1 underwent a liver transplantation in our department. All @entity1 had an upper endoscopy as part of the evaluation before transplantation. @entity1 who had Barrett's mucosa described in their endoscopy report were identified. The records of these @entity1 were retrospectively reviewed. RESULTS: There were seven @entity1 who had Barrett's mucosa in the preoperative endoscopy. Five of these @entity1 (71%) developed an @entity420 in a median time of 66 months after liver transplantation. One had stage II disease and four had @entity5 . Three of them underwent neoadjuvant therapy. All @entity1 underwent an en bloc esophagectomy. One @entity1 developed @entity66 after 12 months and died 37 months after esophagectomy. The other four @entity1 are still alive without recurrence and have a median survival of 16 months. CONCLUSION: @entity418 after liver transplantation is rare, whereas the risk for progression of @entity355 to @entity420 is extremely high. Surveillance endoscopy with aggressive endoscopic treatment of the Barrett's is essential for these @entity1 to prevent them from @entity5 . Furthermore, immunosuppression therapy based on immunosuppressants with antitumoral effects should be preferred. The esophagectomy with neoadjuvant therapy is also in immunosuppressant @entity1 feasible without increased risk for complications.

Progression to @entity420 in XXXX after liver transplantation.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['recurrent disease'] @entity355 :: ('MESH:D001471', 'Disease') :: ["Barrett's esophagus"] @entity5 :: ('MESH:D009369', 'Disease') :: ['stage III disease', 'cancer death', 'malignancies'] @entity418 :: ('MESH:D004938', 'Disease') :: ['Esophageal cancer'] @entity272 :: ('MESH:D012871', 'Disease') :: ['premalignant lesions of the skin and colon'] @entity420 :: ('MESH:D000230', 'Disease') :: ['esophageal adenocarcinoma', 'adenocarcinoma'] @entity7145 :: ('MESH:C562730', 'Disease') :: ['adenocarcinoma of the esophagus']
@entity355 :: (MESH:D001471,Disease) :: ['Barrett's esophagus']
