BACKGROUND: Pregnancy-related @entity5720 may lead to @entity454 . Although this @entity532 had virtually disappeared in high-income countries, we have noted new cases in France over the past few years, all following postpartum @entity548 . STUDY DESIGN: Case series. SETTING _ @entity1 : We retrospectively identified 18 @entity1 from 5 French nephrology departments who developed @entity5720 following postpartum @entity548 in 2009 to  2013. OUTCOMES: Obstetric and renal features, therapeutic measures, and @entity8 outcome were studied. RESULTS: All @entity1 had a severe postpartum @entity548 (mean @entity190 , 2.6  1.1 [SD] L). @entity1344 and disseminated @entity5642 were reported in 5 and 11 @entity1 , respectively. All developed rapid onset of @entity810 and required hemodialysis. Diagnosis of @entity5720 was performed 4 to 33 days following delivery. At 6 months postpartum, 8 @entity1 remained dialysis dependent and none recovered normal kidney function. The length of exposure to @entity927 treatment was significantly more prolonged in @entity1 whose estimated glomerular filtration rate remained  <15mL/ @entity1009 .73m(2) (7.1  4.8 vs 2.9  2.4 hours; P=0.03). LIMITATIONS: Retrospective study; small sample size. CONCLUSIONS: In the setting of gravid endothelium, the conjunction of disseminated @entity5642 with the life-saving use of procoagulant and antifibrinolytic agents (recently implemented in France in a postpartum @entity548 treatment algorithm) may give rise to a risk for uncontrolled clotting in the renal cortex and hence irreversible partial or diffuse cortical @entity39 .

XXXX in Postpartum @entity548 : A Case Series.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'PARTICIPANTS'] @entity8 :: ('MESH:D007674', 'Disease') :: ['kidney disease'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity1009 :: ('966', 'Gene') :: ['min/1'] @entity5720 :: ('MESH:D007681', 'Disease') :: ['renal cortical necrosis'] @entity532 :: ('MESH:D003925', 'Disease') :: ['obstetric complication'] @entity5642 :: ('MESH:D004211', 'Disease') :: ['intravascular coagulation'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute kidney injury'] @entity1344 :: ('MESH:D043171', 'Disease') :: ['Hemodynamic instability'] @entity927 :: ('MESH:D014148', 'Chemical') :: ['tranexamic acid'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal disease']
@entity5720 :: (MESH:D007681,Disease) :: ['Renal Cortical Necrosis']
