Necrotising soft-tissue infections (NSTIs) of the upper limb are uncommon, but potentially life-threatening. We used a national database to investigate the risk factors for amputation of the limb and @entity204 . We extracted data from the Japanese Diagnosis Procedure Combination database on 116 @entity1 (79 @entity1 and 37 @entity1 ) who had a NSTI of the upper extremity between 2007 and 2010. The overall in-hospital mortality was 15.5%. Univariate analysis of in-hospital mortality showed that the significant variables were age (p = 0.015), @entity409 (p = 0.005), @entity8 (P < 0.001), altered consciousness (p = 0.049), and @entity295 (p = 0.021). Logistic regression analysis showed that the factors associated with @entity204 in hospital were age over 70 years ( @entity27894 ; 95% confidence interval (CI) 1.5 to 28.2; p = 0.011) and @entity8 (OR 15.4; 95% CI 3.8 to 62.8; p < 0.001). Univariate analysis of limb amputation showed that the significant variables were @entity6 (p = 0.017) mellitus and @entity295 (p = 0.001). Multivariable logistic regression analysis showed that the factors related to limb amputation were @entity295 (OR 1.8; 95% CI 1.5 to 24.0; p = 0.013) and @entity6 (OR 1.6; 95% CI 1.1 to 21.1; p = 0.038). For NSTIs of the upper extremity, advanced age and @entity8 are both associated with a higher rate of in-hospital mortality. @entity295 and @entity6 are both associated with a higher rate of amputation.

Necrotising soft-tissue infections of the upper limb: risk factors for amputation and XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal dysfunction'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis', 'Sepsis'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes', 'diabetes mellitus'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver dysfunction'] @entity27894 :: ('442186', 'Gene') :: ['Odds Ratio (OR) 6.6'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity204 :: (MESH:D003643,Disease) :: ['death']
