PURPOSE: Computed tomography perfusion (CTP) has been performed to predict which @entity1 with @entity510 are at risk of developing @entity2806 ( @entity2806 ). @entity1 with severe arterial @entity543 may have significant reduction in perfusion. However, many @entity1 have less severe arterial @entity543 . There is a paucity of literature evaluating perfusion changes which occur with mild to moderate @entity543 . The purpose of our study was to investigate serial whole-brain CTP/computed tomography angiography in @entity439 -related @entity510 (aSAH) @entity1 with mild to moderate @entity543 . METHODS: We retrospectively studied 18 aSAH @entity1 who had baseline and follow-up whole-brain CTP/computed tomography angiography. Thirty-one regions of interest/hemisphere at six levels were grouped by vascular territory. Arterial diameters were measured at the circle of Willis. The correlation between arterial diameter and change in CTP values, change in CTP in with and without @entity2806 , and response to intra-arterial vasodilator therapy in @entity2806 @entity1 was evaluated. RESULTS: There was correlation among the overall average @entity450 ( @entity450 ; R=0.49, p<0.04), mean transit time (R=-0.48, p=0.04), and @entity543 . In individual arterial territories, there was correlation between changes in @entity450 and arterial diameter in the middle cerebral artery (R=0.53, p=0.03), posterior cerebral artery (R=0.5, p=0.03), and anterior cerebral artery (R=0.54, p=0.02) territories. Prolonged mean transit time was correlated with arterial diameter @entity543 in the middle cerebral artery territory (R=0.52, p=0.03). @entity1 with @entity2806 tended to have serial worsening of @entity450 compared with those without @entity2806 (p=0.055). CONCLUSIONS: Our preliminary study demonstrates there is a correlation between mild to moderate @entity543 and serial changes in perfusion in @entity1 with aSAH. @entity1 developing @entity2806 tended to have progressively worsening @entity450 compared with those not developing @entity2806 .

Serial Quantitative Computed Tomography Perfusion in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['DCI', 'delayed cerebral ischemia'] @entity510 :: ('MESH:D013345', 'Disease') :: ['aneurysmal subarachnoid hemorrhage', 'subarachnoid hemorrhage'] @entity450 :: ('MESH:D006940', 'Disease') :: ['cerebral blood flow', 'CBF'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysm'] @entity543 :: ('MESH:D016893', 'Disease') :: ['narrowing', 'angiographic narrowing']
@entity510 :: (MESH:D013345,Disease) :: ['Aneurysmal Subarachnoid Hemorrhage']
