OBJECTIVE: The study determines the incidence of SSRI-induced hyponatraemia due to @entity6085 in an elderly @entity146 inpatient population. DESIGN: A retrospective case-note study. SETTING: An acute old age psychiatry ward. SAMPLE: @entity1 admitted from January 1 to December 31, 1996. MEASURES: Demographics, medication, @entity146 diagnoses, plasma @entity1372 level and physical comorbidity were collected. @entity1 on SSRIs were selected and those developing hyponatraemia due to @entity6085 were identified. RESULTS: Of 32 @entity1 taking SSRIs, four developed symptomatic hyponatraemia due to @entity6085 (12.5%). A further four developed asymptomatic hyponatraemia following introduction of an SSRI (12.5%), although laboratory confirmation of @entity6085 was lacking. CONCLUSIONS: The incidence of SSRI-induced hyponatraemia due to @entity6085 has not previously been established. This study shows a high incidence in elderly @entity1 of this potentially dangerous complication. Clinical practice in the prescription of SSRIs to elderly @entity1 must change to include monitoring of electrolytes for early detection and reduction of morbidity.

Incidence of selective serotonin reuptake inhibitor (SSRI) induced hyponatraemia due to the @entity6085 ( XXXX ) secretion in the elderly.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'people'] @entity6085 :: ('MESH:D007177', 'Disease') :: ['SIADH'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity146 :: ('MESH:D001523', 'Disease') :: ['psychiatric']
@entity6085 :: (MESH:D007177,Disease) :: ['SIADH']
