OBJECTIVE: To evaluate the association between @entity626 ( @entity571 ) and body composition parameters, and to analyze the correlations of both @entity28 and lower extremity muscle mass with radiographic knee @entity571 in relation to sex. METHODS: This was a cross-sectional study using data on body composition parameters measured using dual energy X-ray absorptiometry in 4246 @entity1 in the Fifth Korea National Health and Nutrition Examination Survey. The relationships between knee @entity571 and body composition parameters were evaluated. The associations between knee @entity571 and the four subgroups corresponding to @entity28 and muscle mass percentage in both lower extremities were analyzed separately for each sex. RESULTS: The lower extremity muscle mass showed a decreasing trend, while fat parameters showed an increasing linear trend (P for trend <0.05) with increasing severity of knee @entity571 in @entity1 . The odds ratio of each quarter percentile group (25 percentile) for fat parameters showed an increasing trend, while that of the lower extremity muscle mass showed a decreasing linear trend in relation to knee @entity571 in @entity1 (P for trend  <  0.05). In @entity1 , low percentage of lower extremity muscle mass was more associated with knee @entity571 regardless of @entity28 (P  <  0.05). However, there were no associations between all body composition parameters and knee @entity571 in @entity1 . CONCLUSION: In @entity1 , high fat mass and low lower extremity muscle mass were associated with presence and severity of knee @entity571 . Lower extremity muscle mass was more closely correlated with knee @entity571 than @entity28 in @entity1 .

Body composition is more closely related to the development of XXXX in @entity1 than @entity1 : a cross-sectional study using the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V-1, 2).

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'men'] @entity626 :: ('MESH:D020370', 'Disease') :: ['knee osteoarthritis'] @entity571 :: ('MESH:D010003', 'Disease') :: ['OA'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity']
@entity626 :: (MESH:D020370,Disease) :: ['knee osteoarthritis']
