BACKGROUND: Although @entity483 is a @entity272 that can have a major impact on a @entity1 's life, the burden of illness associated with this condition has not been well characterized. OBJECTIVE: To determine the @entity283 ( @entity283 ) of @entity1 with @entity483 by disease severity and to compare it with that of the general public and of @entity1 suffering from other @entity102 or @entity272 . METHODS: Two hundred and thirty-nine @entity483 @entity1 aged 4-70 years completed the Medical Outcomes Study Short Form-36 Health Survey (SF-36) and the Dermatology Life Quality Index (DLQI) or the @entity1 's Dermatology Life Quality Index. These @entity283 scores were compared by self-reported @entity1 disease severity ratings. Health-related quality of life scores were compared with those of the general population and those of @entity1 with other chronic conditions (clinical @entity308 , @entity101 , type 2 @entity6 ) or skin disease ( @entity1569 ). Dermatology Life Quality Index scores were also compared with those of other @entity272 (such as @entity1569 , @entity10272 , and @entity19359 ). RESULTS: @entity1 with @entity483 had @entity75 scores on the SF-36 vitality, social functioning, and mental health subscales compared with individuals in the general population. In seven of eight subscales, individuals reporting more severe disease had @entity75 DLQI and SF-36 scores. @entity1 with @entity483 had @entity1032 compared with those with @entity6 or @entity101 , and @entity6100 compared with @entity1 with @entity101 . When compared with a @entity1569 cohort, @entity1 with @entity483 had @entity75 scores in the role-physical, vitality, social functioning, role-emotional, and mental health SF-36 domains. @entity1 with @entity483 had similar DLQI scores to @entity1 with other chronic @entity66 . CONCLUSIONS: These results demonstrate that @entity483 has an impact on @entity283 , particularly in social functioning and psychological wellbeing. @entity1 -assessed severity of @entity483 correlates with @entity283 decrements, indicating greater @entity283 impact with greater disease severity. @entity483 has as large an impact on @entity283 as several chronic conditions and other dermatologic conditions.

XXXX is associated with a decrement in @entity283 .

@entity1 :: ('9606', 'Species') :: ['Children', 'patient', 'Patients', 'Patient', 'patients'] @entity483 :: ('MESH:D003876', 'Disease') :: ['atopic dermatitis', 'Atopic dermatitis'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['inferior mental health scores'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity6100 :: ('OMIM:300082', 'Disease') :: ['inferior social functioning scores'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity283 :: ('OMIM:603663', 'Disease') :: ['health-related quality of life', 'HRQL'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity1569 :: ('MESH:D011565', 'Disease') :: ['psoriasis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['inferior'] @entity10272 :: ('MESH:D007644', 'Disease') :: ["Darier's disease"] @entity66 :: ('MESH:D004194', 'Disease') :: ['dermatologic diseases'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic illnesses'] @entity19359 :: ('MESH:D016506', 'Disease') :: ['Hailey-Hailey disease'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin diseases', 'chronic skin disease', 'skin disorders']
@entity483 :: (MESH:D003876,Disease) :: ['Atopic dermatitis']
