BACKGROUND/AIMS: Image-enhanced endoscopy (IEE) can differentiate @entity5 from non- @entity5 @entity14 through indirect analysis of pit patterns and microvascular architecture. We evaluated the accuracy of Flexible Spectral Imaging Color Enhancement (FICE) in differentiating @entity5 from non- @entity5 lesions and observer agreement in the analysis of capillary pattern of @entity14 . METHODS: A prospective double-blind trial was conducted in two referral endoscopy centers. Vascular pattern was analyzed by IEE with magnification. Lesions were divided into two groups and examined separately by two experts. Examiners, blinded to each other's interpretations, switched groups and the lesions were reviewed. After 60 days, lesions were reevaluated. RESULTS: In total, 76 @entity1 were referred to colonoscopy for @entity694 screening. Of 100 @entity14 , 88 were @entity5 (73 tubular @entity652 , 10 @entity652 , 1 @entity5493 , 2 serrated @entity652 , 2 @entity420 ) and 12 were non- @entity5 ( @entity1127 ). Mean diameter of the lesions was 6.7mm. Examiners 1 and 2 had 95% accuracy. The interobserver kappa coefficient was 0.80 and the intraobserver kappa coefficient was 0.88 for examiner 1 and 0.73 for examiner 2. CONCLUSION: IEE with magnification is effective for real-time predictive histological diagnosis of @entity14 , with inter- and intraobserver agreement ranging from good to excellent.

Observer agreement for diagnosis of XXXX with analysis of the vascular pattern by image-enhanced endoscopy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5493 :: ('MESH:D018253', 'Disease') :: ['villous adenoma'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['hyperplastic polyps'] @entity5 :: ('MESH:D009369', 'Disease') :: ['neoplastic'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal lesions'] @entity652 :: ('MESH:D000236', 'Disease') :: ['tubulovillous adenomas', 'adenomas'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal lesions']
