BACKGROUND: We aimed to evaluate whether @entity955 ( @entity955 ) measured by tissue Doppler imaging (TDI), which is an indicator for structural and electrical remodelling of the atria, is prolonged in @entity1 with active or inactive @entity2012 , or both, compared with a control group. METHODS: A total of 34 @entity1 with @entity2012 (18 active/16 inactive) and 35 @entity1 as a control group were enrolled. Both intra- and inter- @entity955 were calculated by TDI. The correlation between clinical variables and @entity955 were analyzed. RESULTS: Both inter- @entity955 and right and left intra- @entity955 were prolonged in @entity1 with @entity2012 compared with the control group (P  < 0.001, P < 0.001, and P  = 0.004, respectively). Also, @entity1 with active @entity2012 showed higher inter- @entity955 and right intra- @entity955 compared with @entity1 with inactive @entity2012 (P < 0.05). There was no significant difference in left intra- @entity955 between @entity1 with active @entity2012 and those with inactive @entity2012 (P  =  0.977). The growth hormone and insulin-like growth factor ( @entity442 ) levels positively correlated with inter- @entity955 (r  = 0.577; P < 0.001; r  =  0.614; P < 0.001, respectively). Additionally, we found that inter- @entity955 was significantly and positively correlated with relationship between maximal values of passive mitral inflow (E, PW-Doppler) and lateral early diastolic mitral annular velocities (e', TDI) (r  =  0.316; P  = 0.008). Only the serum @entity442 level was independently associated with inter- @entity955 in multivariate linear regression analysis (b  = 0.500; P  = 0.011). CONCLUSIONS: Our study findings showed that both inter- and intra- @entity955 are prolonged in @entity1 with @entity2012 . Also, @entity955 was observed to be more prolonged in @entity1 with active @entity2012 than in those with inactive @entity2012 . @entity442 was an independent predictor of inter- @entity955 in @entity1 with @entity2012 . Being a noninvasive, inexpensive, and simple technique, @entity955 may be used as an indicator for atrial electrical and structural remodelling in @entity1 with @entity2012 .

The Assessment of Atrial Electromechanical Delay in XXXX With @entity2012 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2012 :: ('MESH:D000172', 'Disease') :: ['acromegaly'] @entity442 :: ('3479', 'Gene') :: ['IGF-1'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial electromechanical delay', 'AEMD']
@entity1 :: (9606,Species) :: ['Patients']
