PURPOSE: We evaluated the prognostic significance of the histology of metastatic lymph nodes to predict postoperative relapse in pathological stage B1 @entity10711 ( @entity10711 ). MATERIALS AND METHODS: A retrospective review of the @entity5 database was performed to identify all @entity1 with clinical stage A @entity10711 who underwent primary retroperitoneal lymph node dissection and were found to have pathological stage B1 disease. No @entity1 received adjuvant chemotherapy and minimal followup was 24 months. RESULTS: A total of 118 @entity1 were identified with a 5-year disease-free survival (DFS) of 68% and a median followup of 43 months. @entity1358 was identified in 92 of 118 (77%) surgical specimens, which was significantly greater than the presence of @entity44 (22%), @entity4797 (16%) and yolk sac (14.4%, p < or = 0.001) with no difference in 5-year DFS comparing the presence or absence of each histology. Solitary histology was noted in 88 of 118 @entity1 (74.5%). @entity1358 was the most common single histology identified at surgery at 64 of 88 (73%), with the incidence of @entity4797 , @entity44 and yolk sac being 12.5%, 9.0% and 5.5%, respectively (p < or = 0.001). There was no statistical difference in DFS for each of the solitary histological subtypes (p=0.67). Recurrence rates were similar for pure @entity1358 (69%), mixed @entity1358 (63%) and no @entity1358 (73%) in the retroperitoneum (p=0.63). CONCLUSIONS: Retroperitoneal histology does not appear to predict outcome in @entity1 with pathological stage B1 @entity10711 .

Does the histology of nodal metastasis predict systemic relapse after retroperitoneal lymph node dissection in pathological stage B1 germ cell XXXX ?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['testicular cancer'] @entity10711 :: ('MESH:C537844', 'Disease') :: ['nonseminomatous germ cell tumor', 'NSGCT'] @entity1358 :: ('MESH:D002292', 'Disease') :: ['Embryonal cell carcinoma', 'embryonal cell carcinoma'] @entity4797 :: ('MESH:D018239', 'Disease') :: ['seminoma'] @entity44 :: ('MESH:D013724', 'Disease') :: ['teratoma']
@entity5 :: (MESH:D009369,Disease) :: ['tumors']
