INTRODUCTION: @entity1 @entity3377 diagnosis is based on isolation of Brucella spp. from blood or tissue cultures with a positivity rate of 40-70% and serology techniques are used as complementary tools; recently molecular biology diagnostic techniques have been developed intending to optimize the etiological confirmation. AIM: The main objective of this work was to compare the polymerase chain reaction (PCR), against serological diagnostic tests during the clinical follow-up of a family presenting @entity3377 . METHODS: Seven family members who lived in the urban area of Mexico City, were monitored using the Rose Bengal test, the agglutination test as well as agglutination with 2 mecapto @entity1068 , blood cultures and serum PCR for a period of 27 months. The suspected source of @entity281 was fresh @entity1237 cheese from a known endemic zone. RESULTS: @entity6467 was isolated from the blood cultures of two @entity1 . All of the @entity1 were positive in serological and PCR tests at the beginning of this follow-up. At the end of the study, three @entity1 responded well to the treatment and showed negative results in the serological and PCR tests. While two @entity1 with @entity6 , showed positive results in the serological and PCR tests as well as persistent symptoms. CONCLUSION: Clinical follow-up of @entity1 with @entity3377 is of great importance, to properly evaluate the given treatment. In this sense the PCR is a great supporting tool in diagnostic testing.

[Clinical, serological and polymerase chain reaction follow-up of a family with XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'Human'] @entity3377 :: ('MESH:D002006', 'Disease') :: ['brucellosis'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus type 2'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity6467 :: ('29459', 'Species') :: ['Brucella melitensis'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol'] @entity1237 :: ('9925', 'Species') :: ['goat']
@entity3377 :: (MESH:D002006,Disease) :: ['brucellosis']
