OBJECTIVE: To evaluate the intraoperative use of @entity1138 to improve the surgical outcome and reduce the rate of soft tissue restenosis in @entity1 undergoing @entity16453 repair. DESIGN: Retrospective chart review of all @entity1 surgically treated for congenital @entity16453 by the senior author (W.F.M). SETTING: Tertiary @entity1 's hospital. @entity1 : Eight consecutive @entity1 with @entity16453 (6 unilateral and 2 bilateral) were compared with 15 historical controls (6 unilateral and 9 bilateral). All study and historical control @entity1 were treated with soft plastic postoperative stenting. INTERVENTION: At the completion of the surgical repair of the @entity16453 , 0.4 mg/mL of topical @entity1138 was applied to the posterior choanae for 3 minutes. MAIN OUTCOME MEASURE: The success rate of the repair of the @entity16453 as determined by the postoperative need for dilation or revision surgical procedures was compared with that of the historical controls. RESULTS: All 8 @entity1 with intraoperative use of @entity1138 were treated with a mean +/- SEM of 0.375 +/- 0.183 dilations per @entity1 . The 15 @entity1 in the control group received a mean +/- SEM of 3.667 +/- 0.583 postoperative dilations for soft tissue restenosis. The difference in the number of postoperative dilations between the study and control group was statistically significant (P =.006) using a t test. CONCLUSIONS: @entity1138 is an effective and reliable treatment for improving the surgical outcome for @entity16453 repair. This may obviate the need for postoperative dilations and may potentially eliminate the need for surgical stenting.

Surgical management of XXXX : improved outcome using @entity1138 .

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient', 'PATIENTS'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin', 'Mitomycin'] @entity16453 :: ('MESH:D002754', 'Disease') :: ['choanal atresia', 'bony choanal atresia']
@entity16453 :: (MESH:D002754,Disease) :: ['choanal atresia']
