BACKGROUND: There is increasing recognition that the risk of @entity64 after left ventricular assist device (LVAD) implantation varies based on gender, with a higher risk in female @entity1 . We reviewed our own data to determine gender differences in the risk of @entity64 . METHODS: Frequency of @entity64 , including @entity932 and @entity385 , was retrospectively evaluated in 110 @entity712 @entity1 (mean age 49.6    13.6 years, 32% @entity1 ) discharged from the hospital after implantation of a HeartMate II (N = 74) or HeartWare (N = 36) LVAD. Competing outcomes analysis was used to determine which clinical risk factors were associated with the risk of @entity64 and @entity204 , with the primary end-point being time to first @entity64 event. RESULTS: During a median follow-up of 1.3 years, 26 @entity1 had a @entity64 (23.6%, 0.14 case per @entity1 -year). The median time to first @entity64 was 0.7 (interquartile range 0.3 to 1.4) years. After adjusting for covariates, risk of @entity64 was higher for @entity1 than for @entity1 (hazard ratio 3.1, 95% confidence interval 1.4 to 6.9; p = 0.007). There was no difference in overall survival between @entity1 and @entity1 . CONCLUSION: The risk of @entity64 after LVAD varies based on gender, with a higher risk in female @entity1 . More research is needed to fully understand these differences, and whether device management strategies should be tailored based on gender.

Gender differences in the risk of XXXX during support with continuous-flow left ventricular assist device.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients', 'person'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity932 :: ('MESH:D020300', 'Disease') :: ['intracranial hemorrhage'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity64 :: (MESH:D020521,Disease) :: ['stroke']
