OBJECT: Information on outcomes of Gamma Knife surgery (GKS) for @entity1 harboring trigeminal @entity808 is limited because these @entity5 are rare. The authors evaluated @entity5 control and functional outcomes in @entity1 who underwent GKS for trigeminal @entity808 to clarify the efficacy of this treatment. METHODS: Forty-two @entity1 with trigeminal @entity808 but no evidence of @entity8605 were treated with GKS at Komaki City Hospital between November 1991 and December 2003. Of these, 37 @entity1 were assessed. The mean @entity5 volume in these @entity1 was 10 cm3. The mean maximum radiation dose directed to the @entity5 was 27.9 Gy and the mean dose directed to the @entity5 margin was 14.2 Gy. The mean follow-up period was 54 months. In four @entity1 (11%) there was complete @entity5 remission; in 20 (54%) there was partial @entity5 remission; in eight (22%) the disease remained stable; and in five (14%) the @entity5 enlarged or uncontrollable @entity158 developed with radiation-induced @entity4 requiring resection. The actuarial 5- and 10-year @entity5 control rates were both 84%. With respect to functional outcomes, 40% of @entity1 noted an improvement in their symptoms, and one @entity1 experienced new symptoms despite @entity5 control. CONCLUSIONS: Gamma Knife surgery was a safe and effective treatment for a select group of @entity1 harboring trigeminal @entity808 . Large @entity5 that compress the brainstem and cause deviation of the fourth ventricle should first be removed surgically and any remnant should be treated by GKS.

Trigeminal XXXX : results of gamma knife surgery in 37 cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity808 :: ('MESH:D009442', 'Disease') :: ['schwannomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'good tumor', 'tumors'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity8605 :: ('MESH:D016518', 'Disease') :: ['neurofibromatosis Type 2'] @entity158 :: ('MESH:D010146', 'Disease') :: ['facial pain']
@entity808 :: (MESH:D009442,Disease) :: ['schwannomas']
