Fumaria indica is used for its anthelmintic, antidyspeptic, cholagogue, diaphoretic, diuretic, laxative, stomachic, tonic properties and claimed to possess various properties for the ailments of blood, skin, @entity149 . The present study was undertaken to evaluate antisecretory, gastroprotective and in-vitro antacid capacity of @entity1068 extract from @entity69840 in @entity35 . Evaluation of @entity69840 extract as antisecretory was carried out by pyloric ligation induced @entity1066 model. The gastroprotective effect was carried out by absolute @entity1068 induced @entity1066 model. Integrity of gastric mucosa was evaluated by estimation of @entity6172 and gastric mucus level. The in-vitro antacid capacity was evaluated by titration method. @entity1068 extract of @entity69840 at 200 mg kg(-1), orally showed inhibition of secretion in pyloric ligation model. @entity6172 level (1.67  g mg(-1) protein), gastricwall mucus (240.76  g g(-1) wet glandular tissue) and percentage protection (77.59%) of @entity1066 were significantly (P < 0.05) increased in absolute @entity1068 induced @entity1066 model. The in-vitro antacid capacity of @entity1068 extract of @entity69840 was compared with the standard. Conclusively, it appears that F. indica possess antisecretory (inhibition of acid secretion), gastroprotective (potentiation of defensive factors) and in-vitro antacid activity.

Evaluation of antisecretory, gastroprotective and in-vitro antacid capacity of Fumaria indica in XXXX .

@entity69840 :: ('312277', 'Species') :: ['F. indica'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer'] @entity149 :: ('MESH:D002493', 'Disease') :: ['gastrointestinal systems and central nervous system'] @entity6172 :: ('D005978', 'Chemical') :: ['GSH'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['Ethanol', 'ethanol']
@entity35 :: (10116,Species) :: ['rats']
