An association between the @entity5337 variant and an increased risk of @entity393 has been reported. Most previous studies were performed with clinically recruited @entity1 and controls. This approach may cause selection bias. The present analysis was performed with the aim to investigate the association between the @entity5337 mutation and the risk of @entity2209 in a population-based sample. The Study of Health in Pomerania (SHIP) is a survey that was carried out in North East Germany. A random sample from the population aged 20 to 79 years was taken. The total SHIP population comprised 4,310 @entity1 . The presence of the @entity5337 variant was determined by PCR and Mnl I digestion. The presence of the @entity5337 variant was neither associated with the number of pregnancies nor with the number of @entity1 per @entity1 . Data from 1,768 females who had at least one pregnancy with known outcome was available for the present analysis. Seventy-three @entity1 (4.1%) reported at least one @entity2209 . @entity1 with and without the @entity5337 mutation did not differ with respect to the number of @entity1 with at least one @entity2209 (OR for @entity5337 variant 1.57; 95%-CI 0.76 - 3.25). Furthermore, the number of @entity1 with two or more @entity2209 , the number of @entity2209 per affected @entity1 and the number of @entity2209 per number of pregnancies per @entity1 was similar between both genotype groups. In conclusion, there is no association between the @entity5337 mutation and the risk of @entity2209 in a representative population sample.

@entity5337 and the risk of XXXX in a German population.

@entity5337 :: ('2153', 'Gene') :: ['factor V Leiden'] @entity1 :: ('9606', 'Species') :: ['participants', 'children', 'women', 'woman', 'patients', 'Women'] @entity393 :: ('MESH:D034381', 'Disease') :: ['pregnancy loss'] @entity2209 :: ('MESH:D050497', 'Disease') :: ['stillbirth', 'stillbirths']
@entity2209 :: (MESH:D050497,Disease) :: ['stillbirth']
