Single institution and population-based studies highlight that infectious complications following transrectal ultrasound guided prostate needle biopsy (TRUS PNB) are increasing. Such @entity281 are largely attributable to @entity1536 resistant microorganisms which colonize the rectal vault and are translocated into the bloodstream during the biopsy procedure. A @entity4279 rectal preparation (PIRP) at time of biopsy is a simple, reproducible method to reduce rectal microorganism colony counts and therefore resultant @entity281 following TRUS PNB. All @entity1 are administered three days of oral antibiotic therapy prior to biopsy. The PIRP technique involves initially positioning the @entity1 in the standard manner for a TRUS PNB. Following digital rectal examination, 15 ml  of a 10% solution of commercially available @entity4279 is mixed with 5 ml  of 1% @entity3303 jelly to create slurry. A 4 cm x 4 cm sterile gauze is soaked in this slurry and then inserted into the rectal vault for 2 min after which it is removed. Thereafter, a disposable @entity2708 gynecologic swab is used to paint both the perianal area and the rectal vault to a distance of 3 cm from the anus. The @entity4279 solution is then allowed to dry for 2 - 3 min prior to proceeding with standard transrectal ultrasonography and subsequent biopsy. This PIRP technique has been in practice at our institution since March of 2012 with an associated reduction of post-biopsy @entity281 from 4.3% to 0.6% (p = 0.02). The principal advantage of this prophylaxis regimen is its simplicity and reproducibility with use of an easily available, inexpensive agent to reduce @entity281 . Furthermore, the technique avoids exposing @entity1 to additional systemic antibiotics with potential further propagation of multi-drug resistant organisms. Usage of PIRP at TRUS PNB, however, is not applicable for @entity1 with @entity1496 or shellfish @entity566 .

XXXX Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1496 :: ('MESH:D007455', 'Chemical') :: ['iodine'] @entity2708 :: ('3635', 'Species') :: ['cotton'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergies'] @entity4279 :: ('MESH:D011206', 'Chemical') :: ['povidone iodine'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity1536 :: ('CHEBI:23765', 'Chemical') :: ['quinolone']
@entity4279 :: (MESH:D011206,Chemical) :: ['Povidone Iodine']
