PURPOSE: Anastomotic strictures are relatively common after radical prostatectomy and are associated with significant morbidity, often requiring multiple surgical interventions. There is controversy in the literature regarding which factors predict the development of @entity850 . In this study we determined predictors of symptomatic @entity850 following contemporary radical prostatectomy. MATERIALS AND METHODS: Between 1999 and 2007, 4,592 consecutive @entity1 underwent radical prostatectomy without prior radiotherapy at our institution. Data were collected from prospective surgical and institutional morbidity databases, and retrospectively from inpatient and outpatient medical and billing records. Cases were assigned a Charlson score to account for comorbidities. Complications were graded according to the modified Clavien classification. RESULTS: Open radical prostatectomy was performed in 3,458 @entity1 (75%) and laparoscopic radical prostatectomy was performed in 1,134 (25%). The laparoscopic radical prostatectomy group included 97 robotic-assisted cases. Median @entity1 age was 59.5 years (IQR 54.7, 64.2). Symptomatic @entity850 developed in 198 @entity1 (4%) after a median postoperative followup of 3.5 months (IQR 2.1, 6.1). On multivariate analysis significant predictors included @entity1 age, body mass index, Charlson score, @entity177 , individual surgeon, surgical approach and the presence of postoperative urine leak or @entity1410 . CONCLUSIONS: @entity1 factors as well as technical factors influence the development of symptomatic @entity850 following contemporary radical prostatectomy. The impact of these factors is influenced by the individual surgeon and the approach used.

Age, obesity, medical comorbidities and surgical technique are predictive of symptomatic XXXX after contemporary radical prostatectomy.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patient', 'men'] @entity850 :: ('MESH:D003251', 'Disease') :: ['anastomotic strictures'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal insufficiency']
@entity850 :: (MESH:D003251,Disease) :: ['anastomotic strictures']
