PURPOSE: To evaluate changes in anterior corneal curvature and graft stability with different sized donor buttons in a laboratory model of @entity9762 . METHODS: Thirty-six @entity1 eye bank corneas (18 donors and 18 recipients) were mounted on an artificial anterior chamber. A manual microkeratome was used to create a hinged anterior lamellar keratectomy. A 7.0-mm diameter posterior lamellar disk (posterior stroma, Descemet's membrane, and endothelium) was then trephinated from the recipient @entity267 . Three different sizes (7.0, 7.25, and 7.5 mm) of donor buttons were compared. They were sutured into the recipient bed with a running 10-0 nylon suture and covered by the host corneal flap. The flap was replaced without sutures. The resulting endokeratoplasty was analyzed by computerized videokeratography and tonometry. RESULTS: Regular postoperative @entity940 was present in all cases. There was an average increase in @entity940 of 1.47 +/- 1.49 diopters (D) postoperatively. The mean change in the average keratometry readings was -5.12 +/- 6.12 D. The grafts and flaps maintained watertight seals with average leak pressures of 66.9 +/- 46.4 mm Hg. Although donor buttons oversized by 0.5 mm had the least change in average keratometry reading, those oversized by 0.25 mm had the best stability at high pressure. All groups had little change in @entity940 . CONCLUSION: The optimal sized button of those tested would be either oversized by 0.25 or 0.5 mm. This new surgical technique may result in lower risk of high and irregular @entity940 in the management of @entity2687 .

A laboratory model for microkeratome-assisted XXXX utilizing a running graft suture and a sutureless hinged flap.

@entity1 :: ('9606', 'Species') :: ['human'] @entity940 :: ('MESH:D001251', 'Disease') :: ['astigmatism'] @entity267 :: ('MESH:D065306', 'Disease') :: ['cornea'] @entity2687 :: ('MESH:D003316', 'Disease') :: ['corneal endothelial disorders'] @entity9762 :: ('MESH:C535342', 'Disease') :: ['posterior lamellar keratoplasty']
@entity9762 :: (MESH:C535342,Disease) :: ['posterior lamellar keratoplasty']
