PURPOSE: The objective of this study is to determine prognostic factors in @entity5606 ( @entity5606 ), including both demographic and treatment variables. @entity1 AND METHODS: A total of 142 @entity1 studied on National @entity3969 Studies 1, 2, 3, 4, and 5 were analyzed. @entity1 were enrolled between the years 1969 and 2002. Variables examined included sex, age of diagnosis, @entity5 stage, presence of CNS lesions, as well as treatment variables, including the use of @entity632 and/or radiotherapy (RT). RESULTS: No survival differences were observed between males and females, between those treated with or without @entity632 , or with or without RT. @entity1 with @entity5 of lower stage had an overall survival rate of 41.8%, whereas, @entity5 of higher stage were associated with a 15.9% survival (P < .001). A highly significant difference in survival was noted when @entity1 were stratified according to age of diagnosis. Survival at 4 years in @entity1 under 6 months of age at diagnosis was 8.8%, whereas, survival in @entity1 2 years of age or older was 41.1% (P < .0001). Stratification into intermediate age brackets demonstrated a strong correlation of increasing survival with increasing age at diagnosis. All @entity1 with a CNS lesion, except one, died. CONCLUSION: Age at diagnosis is a highly significant prognostic factor for survival of @entity1 with @entity5606 . @entity1 have a dismal prognosis, whereas, older @entity1 have a more favorable outcome. @entity5 stage and presence of a CNS lesion were both factors predictive of a poor survival rate.

XXXX in the National @entity3969 Study: age at diagnosis as a prognostic factor.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'PATIENTS', 'infants', 'Infants'] @entity632 :: ('MESH:D004317', 'Chemical') :: ['doxorubicin'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Higher tumor', 'tumors'] @entity5606 :: ('MESH:D018335', 'Disease') :: ['rhabdoid tumor of the kidney', 'RTK'] @entity3969 :: ('MESH:D009396', 'Disease') :: ["Wilms' Tumor"]
@entity5606 :: (MESH:D018335,Disease) :: ['Rhabdoid tumor of the kidney']
