BACKGROUND: Randomised trials have reported higher @entity64 / @entity204 rates after @entity2998 ( @entity2998 ) versus carotid endarterectomy (CEA). Despite this, the 2011 @entity299 ( @entity299 ) guidelines expanded @entity2998 indications, partly because of the Carotid Revascularization Endarterectomy versus Stenting Trial, but also because of improving outcomes in industry sponsored @entity2998 Registries. The aim of this systematic review was: (i) to compare @entity64 / @entity204 rates after @entity2998 /CEA in contemporary dataset registries, (ii) to examine whether published @entity64 / @entity204 rates after @entity2998 fall within @entity299 thresholds, and, (iii) to see if there had been a decline (over time) in procedural risk after @entity2998 /CEA. METHODS: PubMed/Medline, Embase, and Cochrane databases were systematically searched according to the recommendations of the PRISMA statement from January 1, 2008 until February 23, 2015 for administrative dataset registries reporting outcomes after both CEA and @entity2998 . RESULTS: Twenty-one registries reported outcomes involving more than 1,500,000 procedures. @entity64 / @entity204 after @entity2998 was significantly higher than after CEA in 11/21 registries (52%) involving "average risk for CEA" asymptomatic @entity1 and in 11/18 registries (61%) involving "average risk for CEA" symptomatic @entity1 . In another five registries, @entity2998 was associated with higher @entity64 / @entity204 rates than CEA for both symptomatic and asymptomatic @entity1 , but formal statistical comparison was not reported. @entity2998 was associated with @entity64 / @entity204 rates that exceeded risk thresholds recommended by the @entity299 in 9/21 registries (43%) involving "average risk for CEA" asymptomatic @entity1 and in 13/18 registries (72%) involving "average risk for CEA" symptomatic @entity1 . In 5/18 registries (28%), the procedural risk after @entity2998 in "average risk" symptomatic @entity1 exceeded 10%. CONCLUSIONS: Data from contemporary administrative dataset registries suggest that @entity64 / @entity204 rates following @entity2998 remain significantly higher than after CEA and often exceed accepted @entity299 thresholds. There was no evidence of a sustained decline in procedural risk after @entity2998 .

XXXX /Death Rates Following Carotid Artery Stenting and Carotid Endarterectomy in Contemporary Administrative Dataset Registries: A Systematic Review.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'Stroke'] @entity2998 :: ('MESH:D002340', 'Disease') :: ['carotid artery stenting', 'CAS'] @entity299 :: ('MESH:D006331', 'Disease') :: ['AHA', 'American Heart Association'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity64 :: (MESH:D020521,Disease) :: ['Stroke']
