OBJECTIVE: To study the Clinical characteristics of @entity191 ( @entity1726 ) in natural population. METHODS: All the @entity1 diagnosed as @entity304 from a prevalence study in Beijing in 1997 were collected for investigation. The spectrum of the clinical features of @entity304 and the onset, progression and prognosis of @entity1726 were analysed, as well as the impact factors to the prognosis were analysed. RESULTS: 109 cases were ascertained as @entity1726 from the sample population, in which 64(58.7%) were @entity1726 , 11 (10.1%) were @entity304 and 34(31.2%) were symptom @entity304 . 30 of the 64 @entity1726 cases were male. The median age of @entity1726 was 74.5 years. The median age at onset was 68 years old. The median duration was 5 years. The average Hoehn-Yahr staging score was 2.81. The clinical characteristics of @entity1726 and other @entity304 were compared, as asymmetry of symptoms and signs was an important feature to differentiate @entity1726 from other @entity304 . 20.3 percent of @entity1726 cases were associated with @entity303 . 16(25%) of the 64 @entity1726 cases initiated with essential @entity400 and developed to @entity1726 during 6-49 years after the onset of @entity400 . @entity400 was the dominant initial symptoms of @entity1726 (60.9%). Type of initial symptoms was a relatively definite impact factor to the prognosis of @entity1726 . Levodopa treatment was likely to delay the duration of @entity1726 . CONCLUSIONS: The clinical features of @entity304 in natural population were different as compared with previous studies. A further study on the natural history of @entity1726 thoroughly is needed.

[Clinical characteristics of XXXX in natural population].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity304 :: ('MESH:D010302', 'Disease') :: ['Parkinson plus syndrome', 'Parkinsonism'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease"] @entity1726 :: ('OMIM:168600', 'Disease') :: ['PD'] @entity400 :: ('MESH:D014202', 'Disease') :: ['Tremor', 'tremor']
@entity191 :: (MESH:D010300,Disease) :: ['Parkinson's disease']
