To identify clinicopathologic and treatment variables that could predict pathologic @entity5 response to short-term neoadjuvant chemotherapy (NAC) for @entity1 with locally advanced @entity356 . A retrospective analysis was conducted of 178 @entity1 who underwent short-term NAC with EOX regimen followed by surgery from January 2008 to December 2010. Neoadjuvant treatment response was evaluated using @entity5 regression grade. Relationships between pathologic @entity5 response and clinicopathological factors were evaluated using logistic regression analysis. The benefits of regional arterial infusion chemotherapy were investigated separately. The postoperative pathological response rate was 46.1% (82/178) and 4 @entity1 (2.2%) had complete pathological remission. Pathological response was significantly associated with @entity5 differentiation (P   =   0.008), abnormal a-fetoprotein levels (P   =   0.01) and administration approach to chemotherapy (intravenous versus regional arterial infusion chemotherapy) (P   =   0.018). Most @entity236 , @entity391 , @entity390 , @entity1665 , and fatigue were acceptable. Grade 3/4 @entity137 were not commonly observed. The 3-year overall survival (OS) and recurrence free survival (RFS) were 67.0% and 53.0%, respectively. Regional arterial infusion NAC group had significantly better median RFS (48.0 versus 34.0 months) than the intravenous NAC group (P   =   0.049). In conclusion, regional arterial infusion NAC can improve the pathological response rate of advanced @entity356 treated with EOX regimen.

Regional Arterial Infusion Chemotherapy improves the Pathological Response rate for advanced XXXX with Short-term Neoadjuvant Chemotherapy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1665 :: ('MESH:D000505', 'Disease') :: ['alopecia'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicities'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow toxicities'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
