UNASSIGNED: Clinicians currently use different low-weight cut-offs both to diagnose @entity1278 ( @entity1278 ) and to determine @entity1278 severity in adolescent @entity1 . The purpose of this study was to evaluate the clinical utility of existing cut-offs and severity criteria by determining which are most strongly associated with risk for low @entity79 ( @entity79 ). Height adjusted @entity79 Z scores were calculated for 352 females: 262 with @entity1278 and 90 healthy controls (controls) (12-20.5 years), using data from the @entity79 in Childhood Study, for the lumbar spine, whole body less head, and total hip. For most cut-offs used to define low weight (5th or 10th BMI percentile, BMI of 17.5 or 18.5, and 85 or 90% of median BMI), @entity1278 had lower @entity79 Z scores than controls. @entity1278 at >85 or >90% expected body weight for height (EBW-Ht) did not differ in @entity79 Z scores from controls, but differed significantly from @entity1278 at <= 85 or <= 90% EBW-Ht. Among @entity1278 , any @entity2588 was associated with lower @entity79 . @entity1278 had lower @entity79 than controls across @entity4987 and The Society for Adolescent Health and Medicine (SAHM) severity categories. The SAHM moderate severity classification was differentiated from the mildly malnourished classification by lower @entity79 at hip and spine sites. @entity2588 and %EBW-Ht   <=    85 or   <=    90% are markers of severity of @entity604 within @entity1278 . Among severity categories, BMI Z scores (SAHM) may have the greatest utility in assessing the degree of @entity3147 in adolescent @entity1 that corresponds to lower @entity79 .

Impact of low-weight severity and menstrual status on bone in adolescent @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['girls'] @entity604 :: ('MESH:D016301', 'Disease') :: ['bone loss'] @entity4987 :: ('1398', 'Species') :: ['DSM-5'] @entity1278 :: ('MESH:D000856', 'Disease') :: ['anorexia nervosa', 'AN'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity3147 :: ('MESH:D044342', 'Disease') :: ['malnutrition'] @entity2588 :: ('MESH:D000568', 'Disease') :: ['Amenorrhea', 'amenorrhea']
@entity1278 :: (MESH:D000856,Disease) :: ['anorexia nervosa']
