BACKGROUND: To analyze the clinical impact derived from endovascular treatment failure on @entity1 with @entity432 ( @entity432 ) regarding their preoperative clinical stage. METHODS: Retrospective review for primary endovascular procedures for @entity432 from 2008 to 2013. Primary end point included clinical deterioration defined as @entity63 ( @entity63 ) or clinical worsening by, at least, one Rutherford's classification category, related to procedure's failure (restenosis >70% or occlusion). RESULTS: Ninety procedures were analyzed in 85 @entity1 , 87.8% operated due to @entity63 . The lesion treated was classified as Trans-Atlantic Inter-Society Consensus (TASC)-A/B in 76.7%, with a mean length of 98.5      54  mm. Covered stent graft (SG) was used in 31.1% of the cases. Median follow-up was 14.5  months and treatment failure occurred in 33.3% of cases (n  =  30, 9 restenosis and 21 occlusions). Clinical worsening was assessed in 40% of treatment failures and 6 of 21 (28.6%) presented as @entity63 . Twenty-two major adverse limb events (MALEs) were recorded and 8 major amputations. Regarding the type of stent, more occlusions were recorded on @entity1 treated with SG compared with bare metal stent (39.3% vs. 16%; P  =  0.02). However, no differences were found between groups regarding clinical worsening attributable to treatment failure (HR, 1.33; CI 95%, 0.5-3.5; P  =  0.5). On multivariate analysis, TASC-C/D lesions (HR, 5.5; CI 95%, 2.3-13.3; P  <  0.001) and female sex (HR, 4.9; CI 95%, 1.9-12.5; P  =  0.001) behaved as significant predictors for failure and dual-antiplatelet therapy as a protective factor (HR, 0.3; CI 95%, 0.3-0.13; P  =  0.03). No predictors were obtained regarding clinical worsening and occurrence of MALEs in our series. CONCLUSIONS: @entity1 with failure of endovascular procedures on @entity432 appeared with clinical worsening in a no negligible number of cases in our sample regarding their preoperative clinical situation. Thus, we believe that endovascular treatment should be carefully deliberated.

Clinical Outcomes after Endovascular Treatment Failure in XXXX with @entity432 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity432 :: ('MESH:D001157', 'Disease') :: ['femoropopliteal occlusive disease', 'FPOD'] @entity63 :: ('MESH:D007511', 'Disease') :: ['acute limb ischemia', 'ALI', 'critical limb ischemia']
@entity1 :: (9606,Species) :: ['Patients']
