Apoptosis plays an important role in the recovery from @entity631 . Moreover, aberrant apoptosis seems to contribute to @entity1988 . This study compared the intensity of apoptosis in lupus and non- @entity1988 . We used an in situ cell death detection kit, POD, which detects single cell apoptosis in @entity406 -fixed renal tissue. Our material comprised 13 renal biopsy specimens from @entity1 with @entity1988 ( @entity1252 ), 11 renal tissues from @entity1 with non-lupus mesangiocapillary type I @entity631 (MCGN) and 8 normal kidney samples. We checked the correlations between intraglomerular apoptotic cells and the total number of intraglomerular cells, the relationship between tubulointerstitial apoptotic cells and the relative interstitial cortical volume. The population of intraglomerular apoptotic cells was lower in tissues from @entity1252 @entity1 than @entity1 with MCGN. In MCGN the intensity of apoptosis in glomeruli correlated significantly with the number of total glomerular cells. Tubulointerstitial apoptotic cells were infrequent in the kidney samples from @entity1 with @entity1252 and in the normal kidney. In the renal interstitium and tubuli the number of apoptotic cells did not correlate with the relative interstitial cortical volume in kidney tissue in @entity1 with MCGN. In the biopsies from @entity1 with @entity1252 there was an inverse correlation between tubulointerstitial apoptotic cells and the relative interstitial cortical volume, so a low number of apoptotic tubulointerstitial cells was associated with @entity82 in the renal interstitium. The results illustrate the differences in the intensity of apoptosis in lupus and @entity1988 . The low number of apoptotic cells in renal tissue from @entity1 with @entity1252 suggests regulation of apoptosis may be altered in the mechanisms of glomerular and @entity16 in @entity1988 , although the reduced apoptosis may simply be due to smaller numbers of cells in fibrotic areas.

Apoptosis in XXXX and non-lupus mesangiocapillary glomerulonephritis type I MCGN. I. A comparative study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity16 :: ('MESH:D009422', 'Disease') :: ['tubulointerstitial damage'] @entity406 :: ('MESH:D005557', 'Chemical') :: ['formalin'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE-N IV'] @entity1988 :: ('MESH:D008181', 'Disease') :: ['lupus mesangiocapillary glomerulonephritis', 'lupus nephritis', 'non-lupus glomerulonephritis'] @entity631 :: ('MESH:D005921', 'Disease') :: ['glomerulonephritis']
@entity1252 :: (MESH:D008180,Disease) :: ['lupus SLE-N IV']
