BACKGROUND AND PURPOSE: Many studies have suggested a relationship between the type of anesthesia provided during intra-arterial therapy for acute @entity385 and @entity1 outcomes. Variability in blood pressure and @entity551 have previously been identified as possible reasons for worse outcomes in @entity64 . Our aim was to investigate hemodynamic parameters and neurological outcomes of @entity1 receiving either general anesthesia or conscious sedation for intra-arterial therapy of @entity64 . METHODS: We performed a retrospective review of @entity1 undergoing intra-arterial therapy from December 2008 to March 2015. Demographic data, baseline National Institutes of Health @entity64 Scale score, preoperative physiological variables, procedural details, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate, and modified Rankin Scale scores were recorded. RESULTS: 99 @entity1 were included in the study, with 38 receiving general anesthesia and 61 receiving conscious sedation. @entity1 who received general anesthesia had a lower maximum SBP (p=0.02), minimum SBP (p<0.0001), minimum DBP (p<0.0001), and minimum MAP (p<0.0001). On multivariate analysis, general anesthesia was associated with lower minimum SBP (p=0.04), DBP (p=0.02), and MAP (p=0.007). Conscious sedation was associated with more favorable neurological outcomes (p=0.02). @entity1 with favorable neurological outcomes had a lower maximum variability in SBP (p=0.01) and MAP (p=0.03), as well as a higher minimum DBP (p=0.03). CONCLUSIONS: @entity1 with acute @entity385 undergoing intra-arterial therapy with general anesthesia had lower minimum SBP, DBP, and MAP, greater fluctuations in blood pressure, and less favorable outcomes. More studies are needed to examine the implications of variable and reduced blood pressures and neurological outcomes.

Hemodynamics during anesthesia for intra-arterial therapy of acute XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['acute stroke', 'Stroke'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['ischemic stroke']
