Magnetic resonance imaging (MRI) may be an excellent tool to define @entity731 plaque composition, but @entity11644 ( @entity11644 ) suffers from a low signal-to-noise ratio and low resolution of arterial images. Intravascular MRI (IVMRI) represents a potential solution for acquiring high-quality in vivo images of @entity731 . Isolated segments of 11 thoracic @entity1 aortas obtained at autopsy were imaged by IVMRI using an intravascular receiver catheter coil designed and built at our institution. Images obtained by IVMRI were compared with corresponding images obtained by @entity11644 and with histopathological aortic cross sections. The intensity of intimal thickness and plaque components was graded by IVMRI and histopathology using a score of 1 for mild, 2 for moderate, and 3 for severe intensity. IVMRI had an agreement of 75% with histopathology in fibrous cap grading (37.5% expected, kappa = 0.60, P < 0.001) and of 74% in necrotic core grading (39% expected, kappa = 0.57, P < 0.001). Intraplaque calcification was correctly graded by IVMRI in six of the eight plaques in which histopathology recognized @entity460 . The analysis of intimal thickness showed 80% agreement between IVMRI and histopathology (52% expected, kappa = 0.59, P < 0.001). IVMRI image features were similar to those of @entity11644 . In addition, IVMRI accurately determined @entity731 plaque size in comparison with histopathology and @entity11644 (slope = 1.25 cm2, r = 0.99, P < 0.001 for luminal area by IVMRI vs histopathology; slope = 0.97 cm2, r = 0.996, P < 0.001 for luminal area by IVMRI vs @entity11644 ). IVMRI has the potential to provide important prognostic information in @entity1 with @entity731 because of its ability to accurately assess both plaque composition and size.

Intravascular magnetic resonance imaging of XXXX .

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic', 'atherosclerosis', 'atherosclerotic plaques'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity11644 :: ('MESH:C564120', 'Disease') :: ['SMRI', 'surface MRI']
@entity731 :: (MESH:D050197,Disease) :: ['aortic atherosclerotic plaque composition']
