UNASSIGNED: Childhood-onset @entity12040 (c-TA) is a distinct subset affecting a wide age group, ranging from young @entity1 to adolescents and it differs from adult TA in many aspects. There is scarcity of data on c-TA worldwide. The disease is classified using the European League Against @entity627 /Pediatric Rheumatology International Trials Organization/Pediatric Rheumatology European Society criteria. The non-specific nature of presenting complaints and lack of appropriate biomarkers delay the early diagnosis of this illness and many @entity1 present with complications, which become irreversible once they set in. One of the largest cohorts of 40 @entity1 with c-TA from our center reports @entity101 as the commonest presenting feature. @entity262 symptoms like @entity10 , @entity221 and @entity353 are also described. Assessment of disease in c-TA is done by correlating clinical features with raised inflammatory markers. Advanced imaging plays an important role in diagnosis. In c-TA, the role of magnetic resonance angiography is advocated, taking into consideration the enormous amount of radiation exposure with other modalities. Complications of c-TA include cardiovascular, pulmonary, neurological and those arising secondary to long-term @entity479 and immunosuppression therapy.

Childhood-onset XXXX : an update.

@entity1 :: ('9606', 'Species') :: ['children', 'infants'] @entity627 :: ('MESH:D012216', 'Disease') :: ['Rheumatism'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity262 :: ('MESH:D034721', 'Disease') :: ['Systemic'] @entity12040 :: ('MESH:D013625', 'Disease') :: ['Takayasu arteritis'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity12040 :: (MESH:D013625,Disease) :: ['Takayasu arteritis']
