UNASSIGNED: @entity1 with @entity161 have a higher risk of @entity65 and higher mortality from them than does the general population; however, the underlying mechanism remains unclear. Impaired cerebral autoregulation is associated with @entity66 and their mortality. Increased or decreased cerebral blood flow in different brain regions has been reported in @entity1 with @entity161 , which implies @entity73 . This study investigated the cerebral autoregulation in 21 @entity1 with @entity161 and 23 age- and sex-matched healthy controls. None of the @entity1 had a history of @entity65 , @entity101 , or @entity6 . All @entity1 underwent 10-min blood pressure and cerebral blood flow recording through finger plethysmography and Doppler ultrasonography, respectively. Cerebral autoregulation was assessed by analyzing two autoregulation indices: the mean blood pressure and cerebral blood flow correlation coefficient (Mx), and the phase shift between the waveforms of blood pressure and cerebral blood flow determined using transfer function analysis. Compared with the controls, the @entity1 had a significantly higher Mx (0.257 vs. 0.399, p=0.036) and lower phase shift (44.3   vs. 38.7   in the 0.07-0.20Hz frequency band, p=0.019), which indicated impaired maintenance of constant cerebral blood flow and a delayed cerebrovascular autoregulatory response. Impaired cerebral autoregulation may be caused by @entity161 and may not be an artifact of coexisting medical conditions. The mechanism underlying @entity73 in @entity161 and its probable role in the development of @entity66 require further investigation.

Cerebral blood flow autoregulation is impaired in XXXX : A pilot study.

@entity1 :: ('9606', 'Species') :: ['participants', 'Patients', 'patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['cerebrovascular diseases'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impaired cerebral autoregulation'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular diseases']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
