The postpartum period can be a time when profound changes in @entity460 metabolism and @entity79 ( @entity79 ) occur, particularly in association with lactation. We investigated the hypothesis that calciotrophic hormones [ @entity10692 , @entity14257 , and @entity461 ( @entity461 )] are different by lactation practice or hormone status [ @entity4293 ( @entity4293 ), @entity53 , and prolactin] and have a potential role in the @entity604 and recovery associated with lactation. @entity10692 , @entity14257 , @entity461 , femoral @entity79 , @entity4293 , prolactin, @entity53 , and bone turnover markers were measured at 2 wk and at 2, 4, 6, 12, and 18 mo postparturition in 115 postpartum @entity1 aged 20-40 y (parity: 0-1). Lumbar spine @entity79 was measured at 2 wk and at 6, 12, and 18 mo during the postpartum period. @entity461 , @entity10692 , and @entity14257 concentrations were nonlinear across the 18-mo postpartum period. Between baseline and 18 mo postparturition, @entity461 and @entity10692 concentrations did not decline, while there was a substantial decline in @entity14257 concentrations. @entity461 , @entity10692 , and @entity14257 concentrations did not differ by lactation practice or by @entity4293 , @entity53 , or prolactin status. These classic calciotrophic hormones were not associated with concentrations of bone turnover markers or changes in @entity79 in lactating @entity1 . In summary, patterns of change in calciotrophic hormones ( @entity461 , @entity10692 , and @entity14257 ) in the 18-mo postpartum period appeared to be independent of @entity4293 , @entity53 , prolactin, or lactation status and were not associated with bone turnover markers. These data do not support the hypothesis that these three calciotrophic hormones are a central part of the @entity460 mobilization associated with the @entity604 .

Role of calciotrophic hormones in XXXX mobilization of lactation.

@entity1 :: ('9606', 'Species') :: ['women'] @entity10692 :: ('MESH:C097949', 'Chemical') :: ['1,25-dihydroxyvitamin D', '1,25-Dihydroxyvitamin D'] @entity4293 :: ('5744', 'Gene') :: ['PTHrP', 'PTH-related peptide'] @entity604 :: ('MESH:D016301', 'Disease') :: ['bone loss of lactation', 'bone loss'] @entity53 :: ('MESH:D004958', 'Chemical') :: ['estradiol'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity14257 :: ('MESH:C104450', 'Chemical') :: ['25-hydroxyvitamin D'] @entity461 :: ('5741', 'Gene') :: ['PTH', 'parathyroid hormone']
@entity460 :: (MESH:D002118,Chemical) :: ['calcium']
