Recent research has shown that while Lewy body @entity303 . ( @entity21244 ) may be the second most common form of @entity303 , it is difficult to confirm the disease before autopsy. @entity1 with @entity21244 share many clinical signs and symptoms with @entity1 diagnosed with @entity195 ( @entity195 ), making it difficult to differentiate between the two diseases in @entity1 who are still living. Still, our purpose in this study was to determine any clinical features which may differentiate between autopsy-confirmed cases of @entity195 and cases of @entity21244 . We compared 13 @entity1 with autopsy-confirmed @entity195 with 12 @entity1 who had autopsy-confirmed @entity21244 . Phone calls were made to family members of the deceased to help clarify and add any other information not documented in the @entity1 's files. Significant differences were found in three areas, and trends approaching statistical significance were found in two other areas. @entity1833 were more prominent in the @entity1 with @entity21244 than in the @entity1 with @entity195 (10/12 @entity21244 vs. 4/13 @entity195 , P < 0.05). A nonspecific @entity400 was also found more often in the LB @entity1 than in the Alzheimer's @entity1 (8/12 @entity21244 vs. 3/13 @entity195 , P < 0.05). Finally, the LB @entity1 were more prone to wandering, especially earlier in the disease course than were the @entity1 with @entity195 (10/12 @entity21244 vs. 6/13 @entity195 , P < 0.5). There was also a trend within the LB @entity1 for higher use of anxiolytics (9/12 @entity21244 vs. 6/13 @entity195 , P = 0.14) as well as antidepressants (7/12 @entity21244 vs. 4/13 @entity195 , P = 0.16). Our data confirmed our hypothesis that @entity21244 from a clinical perspective is indeed similar to @entity195 . However, the higher incidence of @entity1833 , @entity400 and wandering as well as the trend toward the use of anxiolytics and antidepressants among LB @entity1 was noted. This gives hope that a clinical differentiation between these two diseases and more specific treatments may be possible in the future.

Differentiating between lewy body @entity303 and XXXX : a retrospective brain bank study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity21244 :: ('MESH:D020192', 'Disease') :: ['LBD'] @entity1833 :: ('MESH:D006212', 'Disease') :: ['Visual hallucinations', 'visual hallucinations'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"]
@entity195 :: (MESH:D000544,Disease) :: ['Alzheimer's disease']
