OBJECTIVES: There are an increasing number of reports concerning mitral valve repair by reconstruction of the chordae tendinae with the use of expanded @entity736 ( @entity736 ) sutures. However, little information is available about the extended application or results of this technique for extended prolapse of bilateral mitral leaflets, which is considered to be difficult to repair. METHODS: Between October 1993 and May 1998, 17 @entity1 (age range 16-74 years) who had from moderate to severe @entity339 as the result of a prolapse of bilateral leaflets underwent mitral valve repair by reconstruction of artificial chordae with CV-4 expanded PTFE sutures. Either bilateral or unilateral Kay's suture annuloplasty was also performed to correct annular dilatation in all @entity1 . RESULTS: No operative @entity204 or late mortality was observed. Before discharge, immediate postoperative echocardiography showed less than moderate @entity339 in 16 of 17 @entity1 . The follow-up was completed in all cases by a clinical examination and serial echocardiograms, and the median follow-up period was 52 months (range 27-82 months). There was one failure that required re-operation because of worsening @entity339 (elongation of the anchored side of papillary muscle). When the re-operated @entity1 was excluded from the following data, the degree of @entity339 , estimated by echocardiography performed at recent follow-up, was none in four @entity1 , trivial in eight @entity1 , and mild in four @entity1 . The systolic and diastolic dimensions of the left ventricle decreased significantly (P<0.01). CONCLUSIONS: Because replacement of artificial chordae was not complicated and seemed to preserve fine relationships among leaflet tissues, chordae, and papillary muscles, we therefore suggest that the extensive use of PTFE artificial chordae appears to be a promising procedure for the repair of all kinds of @entity75 causing @entity339 .

Extensive use of XXXX artificial grafts for prolapse of bilateral mitral leaflets.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral regurgitation'] @entity75 :: ('MESH:D001927', 'Disease') :: ['mitral lesions'] @entity736 :: ('CHEBI:53251', 'Chemical') :: ['PTFE', 'polytetrafluoroethylene'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity736 :: (CHEBI:53251,Chemical) :: ['polytetrafluoroethylene']
