BACKGROUND AND PURPOSE: The association between breakfast intake and the risk of @entity65 , including @entity64 , among Asian @entity1 remains unknown. We sought to prospectively investigate whether the omission of breakfast is related to increased risks of @entity64 and @entity301 in general Japanese populations. METHODS: A total of 82 772 @entity1 (38 676 @entity1 and 44 096 @entity1 ) aged 45 to 74 years without histories of @entity65 or @entity5 were followed up from 1995 to 2010. @entity1 were classified as having breakfast 0 to 2, 3 to 4, 5 to 6, or 7 times/wk. The hazard ratios of @entity65 were estimated using Cox proportional hazards models. RESULTS: During the 1 050 030 @entity1 -years of follow-up, we documented a total of 4642 incident cases, 3772 @entity64 (1051 @entity1779 , 417 @entity510 , and 2286 @entity385 ), and 870 @entity301 . Multivariable analysis showed that those consuming no breakfast per week compared with those consuming breakfast everyday had hazard ratios (95% confidence interval; P for trend) of 1.14 (1.01-1.27; 0.013) for total @entity65 , 1.18 (1.04-1.34; 0.007) for @entity64 , and 1.36 (1.10-1.70; 0.004) for @entity1779 . Similar results were observed even after exclusion of early cardiovascular events. No significant association between the frequency of breakfast intake and the risk of @entity301 was observed. CONCLUSIONS: The frequency of breakfast intake was inversely associated with the risk of @entity64 , especially @entity1779 in Japanese, suggesting that eating breakfast everyday may be beneficial for the prevention of @entity64 .

Association of Breakfast Intake With Incident @entity64 and XXXX : The Japan Public Health Center-Based Study.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Participants', 'person', 'people', 'men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['strokes', 'stroke', 'total stroke'] @entity301 :: ('MESH:D003327', 'Disease') :: ['coronary heart disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity510 :: ('MESH:D013345', 'Disease') :: ['subarachnoid hemorrhages'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['cerebral hemorrhages', 'cerebral hemorrhage'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease'] @entity385 :: ('MESH:D002544', 'Disease') :: ['cerebral infarctions']
@entity301 :: (MESH:D003327,Disease) :: ['Coronary Heart Disease']
