OBJECTIVE: To determine the proportion of @entity1 in Victoria treated within the British Heart Foundation 90-minute call-to-needle (CTN) time benchmark for thrombolysis of @entity583 ( @entity583 ), and to validate the British Heart Foundation 90-minute benchmark with respect to mortality. DESIGN: Cohort study. SETTING: 20 hospitals and two ambulance services in the State of Victoria, Australia. @entity1 : 1147 @entity1 with @entity583 transported to hospital by ambulance and eligible for thrombolysis. MAIN OUTCOME MEASURES: CTN time, and in-hospital mortality. RESULTS: Median CTN time was 83 minutes (mean, 93.2 min; range, 29-894 min). Median door-to-needle (DTN) time was 37 minutes (mean, 46.5 min; range, 0-853 min). 61% of @entity1 received thrombolysis within the 90-minute benchmark. @entity1 with CTN times > 90 minutes had an increased risk of dying (relative risk, 1.8; 95% CI, 1.3-2.7). Factors associated with CTN time < 90 minutes were lower DTN time, prior notification of the receiving hospital and transport time less than 20 minutes. CONCLUSION: The British Heart Foundation CTN time benchmark is being met for 61% of eligible @entity583 @entity1 in Victoria. Strategies to reduce CTN time should be region-specific, and should include attempts to reduce @entity35801 and to enhance ambulance-hospital communication. Prehospital thrombolysis may be appropriate for some regions.

Call-to-needle times for thrombolysis in acute XXXX in Victoria.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PARTICIPANTS'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST-elevation myocardial infarction'] @entity35801 :: ('CHEBI:32671', 'Chemical') :: ['DTN']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
