INTRODUCTION: @entity1 with @entity1468 are at risk for @entity65 [1,2]. Changes in cardiac function are subtle in @entity1468 and are quantitatively difficult with conventional imaging. Strain measurements using speckle-tracking echocardiography have been used to sensitively quantifyabnormalities in other disease settings [3]. OBJECTIVES: The objective of this study was to evaluate changes in myocardial strain using speckle tracking echocardiography in @entity1 with and without @entity1468 . We hypothesized that global left systolic strain measures would prove more sensitive than conventional left ventricular ejection fraction in detecting early changes in systolic LV function manifesting as @entity66 prior to overt progression. METHODS: We evaluated the feasibility and sensitivity of strain imaging using speckle tracking echocardiography. Thirty-six @entity1 were enrolled in this pilot study; 28 were analyzed: 11 with @entity1468 and 17 without @entity1468 . Echocardiographic Ejection fraction and @entity2026 ,radial and circumferential strain were measured. RESULTS: Global Median longitudinal strain was significantly worsened in @entity1 with @entity1468 compared to @entity1 without @entity1468 (P<0.0001). Similar results were observed for global radial strain (P=0.006) and circumferential strain (P=0.03). There was no significant difference in ejection fraction between the groups (P=0.52) (Table 1). Data are presented as median (interquartile range). CONCLUSION: Myocardial strain imaging using speckle tracking is more sensitive than left ventricular ejection fraction to detect differences in left ventricular systolic function in @entity1 with and without @entity1468 .

OS094. Subclinical left ventricular dysfunction in preeclamptic XXXX with preserved left ventricular ejection fraction: A 2D speckle tracking imaging study.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['subclinical disease'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['global peak longitudinal'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['preeclampsia'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease']
@entity1 :: (9606,Species) :: ['women']
