OBJECTIVE: The objective of the study was to compare long-term results of @entity1661 for benign uterine diseases 14 years after hysterectomy, with @entity322 as the primary outcome measure. STUDY DESIGN: This was a long-term follow-up of a multicenter, randomized clinical trial without blinding. Eleven gynecological departments in Denmark contributed @entity1 to the trial. @entity1 referred for benign uterine diseases who did not have contraindications to subtotal abdominal hysterectomy were randomized to subtotal (n  = 161) vs total (n  = 158) abdominal hysterectomy. All @entity1 enrolled in the trial from 1996 to 2000 who were still alive and living in Denmark (n  = 304) were invited to answer the validated questionnaire used in prior 1 and 5 year follow-ups. Hospital contacts possibly related to hysterectomy from 5 to 14 years postoperatively were registered from discharge summaries from all public hospitals in Denmark. The results were analyzed as intention to treat and per protocol. Possible bias caused by missing data was handled by multiple imputation. The primary outcome was  @entity322 ; the secondary outcomes were @entity3577 , @entity1142 , @entity158 , sexuality, quality of life (Short Form-36 questionnaire), hospital contacts, and @entity3556 . RESULTS: The questionnaire was answered by 197 of 304 @entity1 (64.8%) (subtotal hysterectomy [n  = 97] [63.4%]; total hysterectomy [n  = 100] [66.2%]). Mean follow-up time was 14 years and mean age at follow-up was 60.1 years. After subtotal abdominal hysterectomy, 32 of 97 @entity1 (33%) complained of @entity322 compared with 20 of 100 @entity1 (20%) after total abdominal hysterectomy 14 years after hysterectomy (relative risk, 1.67; 95% confidence interval, 1.02-2.70; P  = .035). After a multiple imputation analysis, this difference disappeared (relative risk, 1.36; 95% confidence interval, 0.86-2.13; P  = .19). No differences were seen in any of the secondary outcomes. CONCLUSION: Subtotal abdominal hysterectomy was not superior to total abdominal hysterectomy on any outcomes. More @entity1 seem to have subjective @entity322 14 years after subtotal abdominal hysterectomy. This result was not confirmed by multiple imputation analysis and should be interpreted cautiously.

XXXX : randomized clinical trial with 14-year questionnaire follow-up.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Women'] @entity322 :: ('MESH:D014549', 'Disease') :: ['urinary incontinence'] @entity3556 :: ('MESH:D014592', 'Disease') :: ['vaginal bleeding'] @entity1661 :: ('MESH:D000008', 'Disease') :: ['subtotal vs total abdominal hysterectomy'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation'] @entity3577 :: ('MESH:D056887', 'Disease') :: ['pelvic organ prolapse']
@entity1661 :: (MESH:D000008,Disease) :: ['Subtotal versus total abdominal hysterectomy']
