Several histological variants of @entity14 have been reported, some of them bearing prognostic significance, others only incidental findings showing unusual morphological features. The current report was aimed to describe the histological, immunohistochemical and ultrastructural features of an oncocytic @entity188 occurring in a 66-year-old @entity1 . Histologically, it was a moderately differentiated @entity420 composed by glandular structures lined by eosinophilic cells. The latter showed abundant granular cytoplasm and large nuclei with prominent nucleoli. Several glandular structures contained intraluminal, basophilic and non-birifrangent microcalcifications. The @entity5 cells displayed consistent anti-mitochondrial antigen, carcinoembryonic antigen, @entity876 , @entity6628 and @entity2225 immunoreactivity. Ultrastructurally, more than 80% of the cytoplasmic area was occupied by abnormal mitochondria, while exocrine or endocrine granules were undetectable. The @entity5 infiltrated the intestinal wall through the subserosal tissue, but lymph node or distant metastases were absent. The @entity1 is disease free 22 months after surgery. Based on the above features, this case could be appropriately named @entity420 with intraluminal microcalcifications. Like @entity356 showing similar morphologic features, this @entity5 might have a better prognosis, and the presence of microcalcifcations could help its proper recognition at a pre-operative stage.

Oncocytic XXXX with diffuse intra-luminal microcalcifications: the first reported case.

@entity1 :: ('9606', 'Species') :: ['woman', 'patient'] @entity6628 :: ('1045', 'Gene') :: ['CDX2'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity2225 :: ('54474', 'Gene') :: ['cytokeratin 20'] @entity188 :: ('MESH:D012004', 'Disease') :: ['adenocarcinoma of the rectum'] @entity876 :: ('7157', 'Gene') :: ['p53'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal carcinoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['oncocytic adenocarcinoma', 'adenocarcinoma'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric neoplasms']
@entity188 :: (MESH:D012004,Disease) :: ['adenocarcinoma of the rectum']
