BACKGROUND: Dynamic variables based on the heart-lung interaction induced by positive pressure ventilation have not been shown to be useful in assessing cardiac preload in pediatric @entity1 . OBJECTIVE: To evaluate whether @entity64 volume variation ( @entity6355 ) obtained from the FloTrac/Vigileo(TM) monitoring system can reflect a change in blood volume during the blood removal and fluid replacement protocol in @entity697 ( @entity697 ). METHODS: Sixteen pediatric @entity1 scheduled for elective cranioplasty were recruited. In the @entity697 protocol, 10 ml  kg(-1) blood removal and fluid replacement were performed. @entity6355 , heart rate, mean blood pressure, and femoral venous pressure were recorded. Differences at four time points (T0: baseline, T1: 5 ml  kg(-1) @entity190 , T2: 10 ml  kg(-1) @entity190 , and T3: after fluid replacement) during @entity697 were compared. The blood volume (EBV) was estimated as 70 ml  kg(-1) at T0 and decreased to 60 ml  kg(-1) at T2. RESULTS: Of the 16 @entity1 , four were excluded and 12 were analyzed. Significant differences in all of the parameters were observed between each time point. The @entity6355 significantly increased after the blood removal and decreased after the fluid replacement (P < 0.01, Bonferroni adjustment). In addition, the increases in @entity6355 during the blood removal, T0-T1 and T0-T2, were 70%    40% and 159%    91%, respectively. @entity6355 showed a significant correlation with EBV during the blood removal in @entity697 (rs = -0.68, 95% confidence interval -0.73 to -0.63, P < 0.001). CONCLUSION: @entity64 volume variation obtained from the FloTrac/Vigileo(TM) monitoring system revealed a strong correlation with EBV during @entity697 without surgical stimulation. The usefulness of this device as an indicator of cardiac preload under @entity3485 or normovolemic conditions in @entity1 during surgery remains to be determined.

Usefulness of @entity64 volume variation to assess blood volume during blood removal for autologous blood transfusion in pediatric XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity6355 :: ('35246', 'Species') :: ['SVV'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'Stroke'] @entity697 :: ('MESH:D000208', 'Disease') :: ['ANH', 'acute normovolemic hemodilution'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity3485 :: ('MESH:D020896', 'Disease') :: ['hypovolemic']
@entity1 :: (9606,Species) :: ['patients']
