Central visual acuity is usually maintained until late in the course of @entity726 . Ten @entity1 (5 @entity1 , 5 @entity1 ) between the ages of 25 and 79 were found to have decreased visual acuity associated with central or centrocaecal @entity1019 early in their course. Five @entity1 had chronic open-angle glucoma, three and @entity1538 , one and @entity726 , and one had @entity8707 . A Marcus Gunn pupil was present in all six @entity1 not on miotics. Most lost central acuity at pressures under 30 mmHg. Seven @entity1 had vision of 20/200 or less. All with marked @entity227 had a cup disc rate of .8 or greater. Other causes were carefully ruled out. Proposed mechanisms for the development of these central defects include either @entity1019 which extend centrally or early papillomacular bundle involvement due to temporal cupping. This study demonstrates that @entity227 with associated central field loss can be a relatively early finding in @entity726 .

Early loss of central visual acuity in XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual loss', 'decreased vision'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['pigmentary glaucoma'] @entity8707 :: ('MESH:C535679', 'Disease') :: ["Axenfeld's syndrome"] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma', 'juvenile glaucoma'] @entity1019 :: ('MESH:D012607', 'Disease') :: ['double Bjerrum scotomas', 'scotomas']
@entity726 :: (MESH:D005901,Disease) :: ['glaucoma']
