BACKGROUND: Small deep brain @entity1188 are often caused by two different vascular pathologies: 1. @entity432 at the orifice of large caliber penetrating arteries termed branch @entity66 (BAD) and 2. lipohyalinotic degenerative changes termed @entity528 ( @entity528 ). We herein analyze and describe the characteristics of these 2 different pathologies. METHODS: We studied 394 @entity1 with penetrating @entity1188 in the territories of the lenticulostriate arteries and anterior pontine arteries. Radiologically defined BAD of the lenticulostriate arteries was defined as @entity1188 with size more than 10mm in diameter on axial slice and visible for 3 or more axial slices, and that of the anterior pontine arteries was defined as unilateral @entity1188 extending to the basal surface of the pons. Within each of the 2 territory groups, differences between BAD and @entity528 were compared. RESULTS: Ninety five @entity1 in the lenticulostriate arteries group (36.1%) and 78 @entity1 in anterior pontine arteries group (59.5%) were classified as BAD. Initial NIHSS, incidence of @entity51 and poor functional outcome were significantly higher and incidence of concomitant silent @entity1188 tended to be lower in BAD than @entity528 . In logistic regression analysis, BAD compared with @entity528 was independently associated with @entity16803 , in lenticulostriate arteries group (OR: 4.21, p=0.0001) and in anterior pontine arteries group (OR: 5.32, p=0.0018). CONCLUSIONS: Radiologically defined BAD and @entity528 had different characteristics. BAD was significantly associated with @entity51 and considered as a major vascular mechanism of @entity51 in penetrating @entity1188 .

Characteristics of intracranial branch XXXX and its association with @entity51 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['atheromatous disease'] @entity16803 :: ('MESH:D020371', 'Disease') :: ['PMD'] @entity51 :: ('MESH:D009461', 'Disease') :: ['progressive motor deficits'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['artery infarcts', 'lacunar infarcts', 'infarcts', 'artery territory infarcts'] @entity432 :: ('MESH:D001157', 'Disease') :: ['atheromatous occlusion'] @entity528 :: ('MESH:D009410', 'Disease') :: ['LD', 'lipohyalinotic degeneration']
@entity66 :: (MESH:D004194,Disease) :: ['atheromatous disease']
