PURPOSE: @entity6872 are @entity5 localized to the sellar region arising from plasma cells. Knowledge of clinical, imaging, surgical, and pathological characteristics is limited to single case reports. METHODS: A retrospective analysis of five primary cases was conducted, followed by systematic review of English language articles using PubMed in accordance with PRISMA guidelines. RESULTS: Five primary case @entity1 include four @entity1 and one @entity1 , ages 60-77, followed up to 3  years. A systematic review identified 65 additional @entity1 , of whom 65% presented with @entity129 and 15% with @entity4614 . Sixteen percent had history of known @entity1582 ( @entity1582 ) while 37% were diagnosed concurrently with @entity1582 on presentation of @entity6872 . Imaging showed median @entity5 size of 38  mm (range, 4-70  mm), with MRI intensity similar to that of other sellar masses. Surgical biopsy with immunohistochemical studies confirmed plasmacytoma diagnosis. Eighty-one percent underwent parasellar radiotherapy, and chemotherapy initiated in 59% of the 69 @entity1 with @entity1582 . Overall survival rate was 74% at follow-up (median 12  months), with 18% having parasellar recurrences and 38% progressing to systemic @entity1582 after presentation of a solitary plasmacytoma (median 3  months). CONCLUSIONS: @entity6872 are @entity5 that should be considered in the differential diagnosis for lesions involving the sella and arising from the clivus, especially when @entity129 paresis is apparent, even in the absence of known @entity1582 . Although recurrence rates for @entity6872 is low, @entity1 should be monitored for progression to @entity1582 . Treatment depends on the presence of @entity262 at diagnosis.

Sellar and clival plasmacytomas: case series of 5 XXXX with systematic review of 65 published cases.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'men'] @entity129 :: ('MESH:D003389', 'Disease') :: ['cranial nerve palsies', 'cranial nerve'] @entity6872 :: ('MESH:D010954', 'Disease') :: ['Parasellar plasmacytomas', 'parasellar plasmacytoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'rare tumors'] @entity262 :: ('MESH:D034721', 'Disease') :: ['systemic disease'] @entity1582 :: ('MESH:D009101', 'Disease') :: ['multiple myeloma', 'MM'] @entity4614 :: ('MESH:D007018', 'Disease') :: ['hypopituitarism']
@entity1 :: (9606,Species) :: ['patients']
