PURPOSE: @entity2194 that can lead to irreversible @entity1781 and cause @entity1939 . Optical coherence tomography (OCT) allows an early diagnosis of @entity726 by the measurements of the retinal nerve fiber and optic disc parameters. A retrospective study was designed to analyze the effects of the measurement of the retinal nerve fiber layer (RNFL) thickness and the optic disc tomography by spectral-domain OCT on the early diagnosis of suspected @entity726 and @entity725 ( @entity725 ). METHODS: This was a clinical case-control study. The RNFL thickness around the optic disc and optic disk tomographic parameters of the control (n = 51, 98 eyes), suspected @entity726 (n = 81, 146 eyes), and @entity725 groups (n = 55, 106 eyes) were measured by OCT. The parameters included superior, inferior, nasal and temporal mean RNFL thickness, disc area (DA), cup area (CA), @entity14726 ( @entity14726 ), disc volume (DV), cup volume (CV), rim volume (RV), cup/disc area ratio (CA/DA), rim/disc area ratio ( @entity14726 /DA), cup/disc volume ratio (CV/DV) and rim/disc volume ratio (RV/DV). RESULTS: Superior, nasal, and mean RNFL parameters, DA, CA, @entity14726 , DV, CV, CA/DA, @entity14726 /DA, CV/DV and RV/DV significantly differed among three groups by single-factorial ANOVA. Inferior and temporal RNFL thickness significantly differed between the control and @entity725 groups. No significant difference was observed in RV among three groups. In the @entity725 group, the maximum area under the ROC curve (AROC) of mean RNFL thickness was 0.845. The maximum AROC of optic disk parameters was @entity14726 /DA (0.998), followed by CA/DA (0.997). The AROC of CA, @entity14726 , CV, and DV were all > 0.900. CONCLUSION: OCT may serve as a useful diagnostic modality in distinguishing suspected @entity726 from @entity725 .

Role of Retinal Nerve Fiber Layer Thickness and Optic Disk Measurement by OCT on Early Diagnosis of XXXX .

@entity725 :: ('MESH:C562750', 'Disease') :: ['POAG', 'primary open angle glaucoma'] @entity2194 :: ('MESH:D005128', 'Disease') :: ['Glaucoma is an eye disease'] @entity14726 :: ('MESH:C536816', 'Disease') :: ['RA', 'rim area'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity1939 :: ('MESH:D001766', 'Disease') :: ['blindness'] @entity1781 :: ('MESH:D009901', 'Disease') :: ['optic nerve damage']
@entity726 :: (MESH:D005901,Disease) :: ['Glaucoma']
