UNASSIGNED: Associations between farming exposures and @entity402 can vary by timing of exposure and sex. We examined associations between adult @entity402 , sex, and farm living in a rural Canadian population. In 2010, we conducted a baseline survey of 11,982 households located in four agricultural regions of Saskatchewan, Canada. Of the 7225 adults aged 18-75, 1658 underwent clinical assessments including skin testing. Of these, 1599 @entity1 underwent skin prick testing to four common allergens. We defined @entity402 as >3 mm reaction to any of four allergens compared with saline control. Farming exposures were farm living in the first year of life and current farm living. All analyses were stratified by sex. The prevalence of @entity402 was 17.8% and was higher in @entity1 than @entity1 (P < .001). The most common @entity566 was to grasses (8.8%) followed by house dust mite (HDM) mixed (8.1%). Atopy was lower in those subjects with an early farm exposure (P = .08) and who were female (P = .03). After adjusting for education, age, and smoking status, both current and early farm exposures were associated with decreased sensitization to cat @entity402 in @entity1 that was stronger with current exposure (P < .05). @entity1 had significantly decreased atopic sensitization to Alternaria with an early farm exposure and @entity101 with a current farm exposure. In this rural population, the protective effect of an early farm exposure for any @entity402 was weak overall. The impact of farming exposures on @entity402 was allergen dependent and varied by sex.

Farm Exposure and Atopy in @entity1 and XXXX : The Saskatchewan Rural Health Study.

@entity402 :: ('MESH:C564133', 'Disease') :: ['atopy'] @entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Men', 'men'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergy'] @entity101 :: ('MESH:D006973', 'Disease') :: ['increased atopic sensitization to HDM']
@entity1 :: (9606,Species) :: ['Women']
