BACKGROUND: Violaceous @entity272 that progress to nonhealing ulcerations and gangrene characterize @entity13375 . These lesions, which are associated with @entity3528 , are resistant to medical therapy and may lead to amputation, uncontrollable @entity295 , and @entity204 . METHODS: In this retrospective analysis, @entity1 , disease, and treatment variables were obtained from the @entity1 ' medical records. Paired t-tests, chi-square analysis, and two-tailed Fisher's exact tests compared variables. Survival curves were generated using the Kaplan-Meier method; the log-rank test determined survival differences. RESULTS: From 1993 to 2001, 35 @entity1 were treated; 26 (74%) were female and 20 (57%) were African-American. The cause of the @entity177 was @entity101 in 37% and @entity6 in 26%. Twenty-three @entity1 (66%) underwent a parathyroid resection involving 4 glands and autotransplantation in 12, 3(1/2) glands in 7, and <3(1/2) glands in 4. Median follow-up was 26 months (range 2 to 90 months). Surgical @entity1 showed improvement in serum @entity460 , @entity1391 , and parathyroid hormone values (P<.05) and had a longer median overall survival (80 months) than nonsurgical @entity1 (35 months) (P<.001). CONCLUSIONS: Parathyroid resection for @entity13375 reduces serum @entity460 , @entity1391 , and parathyroid hormone values and improves clinical response and overall survival.

Therapy for XXXX : an outcome analysis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity3528 :: ('MESH:D006962', 'Disease') :: ['secondary hyperparathyroidism'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity1391 :: ('CHEBI:26020', 'Chemical') :: ['phosphate'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesions'] @entity13375 :: ('MESH:D002115', 'Disease') :: ['calciphylaxis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity13375 :: (MESH:D002115,Disease) :: ['calciphylaxis']
