BACKGROUND AND AIMS: Neoadjuvant radiation and chemotherapy in @entity5 reduces local recurrences and increases the rate of conservative sphincter surgery. However, an increase in postoperative morbidity and mortality has also been observed. This study analyzed the operative @entity260 in @entity1 with this treatment. @entity1 AND METHODS: Retrospective review of 103 @entity1 with @entity5 , divided into two groups: group A, 53 @entity1 undergoing preoperative radiotherapy with 45 Gy combined with chemotherapy, and group B, 50 @entity1 with @entity5 who received surgery after diagnosis. Both groups were homogeneous. The two groups were compared for both technical difficulty, using intraoperative data and rate of complications. RESULTS: There were no statistically significant differences between the two groups with regard to intraoperative or postoperative data. In group A there were 20 complications in 17 @entity1 (32%) and in group B 22 complications in 19 @entity1 (38%). The rates of perineal wound infection were similar. The percentage of @entity834 was higher in group A. A greater number of anterior resections was performed in group A. CONCLUSION: Preoperative radiation and chemotherapy in @entity5 does not @entity260 and increases the rate of sphincter-preserving surgery.

Neoadjuvant radiation and chemotherapy in XXXX does not @entity260 .

@entity5 :: ('MESH:D009369', 'Disease') :: ['rectal cancer'] @entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity834 :: ('MESH:D057868', 'Disease') :: ['anastomotic leaks'] @entity260 :: ('MESH:D011183', 'Disease') :: ['increase postoperative complications', 'difficulty and postoperative complications']
@entity5 :: (MESH:D009369,Disease) :: ['rectal cancer']
