PURPOSE: A concomitant @entity5971 , presenting within the first 6 months of life, associated with a high incidence of @entity4785 , manifest @entity346 and asymmetric optokinetic nystagmus is termed @entity5971 . Most studies concern @entity1 diagnosed in infancy and treated throughout childhood. This paper addresses the factors that may influence the development of @entity4457 in @entity1 who remain untreated until visual adulthood. METHODS: During a 3 year period 113 @entity1 aged 8 years or more with a history of @entity5971 occurring within the first 6 months of life were examined for the study. All @entity1 underwent full ocular motility assessment and cycloplegic refraction, and only those with one or more signs of @entity5971 were included. RESULTS: Of the 113 @entity1 , 16 (14.3%) had a difference of 2 or more lines in the visual acuity of the two eyes and were diagnosed as having @entity4457 . @entity9340 was present in 10 of the 16 (62.5%). The correlation between @entity9340 and @entity4457 was statistically significant (p = 0.0001). CONCLUSIONS: @entity4457 following early surgical intervention in essential @entity5770 is well documented, but the risk is outweighed by the chance of obtaining some form of binocular vision. However, where access to ongoing therapy is not available, @entity1 with @entity5971 , free alternation and no @entity9340 have a significant chance of retaining good visual acuity in both eyes if surgery is delayed until visual adulthood.

Untreated XXXX : factors affecting the development of @entity4457 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5770 :: ('MESH:D005099', 'Disease') :: ['infantile exotropia'] @entity4785 :: ('MESH:D004213', 'Disease') :: ['dissociated vertical deviation'] @entity5971 :: ('MESH:D004948', 'Disease') :: ['essential infantile esotropia', 'esotropia'] @entity9340 :: ('MESH:D015858', 'Disease') :: ['anisometropia', 'Anisometropia'] @entity346 :: ('MESH:D009759', 'Disease') :: ['latent nystagmus'] @entity4457 :: ('MESH:D000550', 'Disease') :: ['amblyopia', 'Amblyopia']
@entity5971 :: (MESH:D004948,Disease) :: ['essential infantile esotropia']
