BACKGROUND: Some @entity418 @entity1 may have residual nodal @entity3 following pathologic complete response (pCR) of the @entity5 after neoadjuvant chemoradiotherapy (CRT). This study examines the prognosis according to lymph node @entity3 in pathologic T0 @entity1 who received neoadjuvant CRT followed by surgery for @entity1721 (SCC). METHODS: Prospectively-collected data from @entity1 who underwent protocol-based esophageal resection and reconstruction after neoadjuvant CRT for esophageal SCC from 2000 to 2010 at the Asan Medical Center, Seoul, Korea, were retrospectively studied. @entity1349 ( @entity1349 ), @entity1349 ( @entity1349 ), and risk factors for ypT0N1 were analyzed and compared with ypT0N0. RESULTS: A total of 211 @entity1 underwent prospective, protocol-based esophageal resection and reconstruction after neoadjuvant CRT for esophageal SCC. Of these, 123 @entity1 had a pCR of the @entity5 and were enrolled in this study. Lymph node status was ypT0N0 in 103 @entity1 and ypT0N1 in 20 @entity1 . The two groups did not show significant differences in sex, initial clinical stage, @entity5 location, and histologic grade. Recurrence occurred in 13 @entity1 (12.6  %) with ypT0N0 and six @entity1 (30.0  %) with ypT0N1, respectively (p  =  0.083). Five-year @entity1349 and @entity1349 of ypT0N1 were 42.8      13.9 and 41.7      12.8  %, respectively. Survival was compared between the two groups using a log-rank test, and there were no significant differences for @entity1349 or @entity1349 . CONCLUSIONS: Residual lymph node @entity3 did not significantly influence prognosis in pathologic T0 @entity1 who received neoadjuvant CRT followed by surgery for esophageal SCC.

Oncologic Outcomes According to Remnant Lymph Node Metastases in Pathologic T0 (ypT0) XXXX Following Prospective Neoadjuvant Therapy and Surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumor'] @entity1721 :: ('MESH:C562729', 'Disease') :: ['esophageal squamous cell carcinoma'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'RFS', 'Overall survival', 'recurrence-free survival']
@entity1721 :: (MESH:C562729,Disease) :: ['Esophageal Squamous Cell Carcinoma']
