AIM: @entity1887 , or valvitis, has recently been identified using Doppler echocardiography in cases of @entity4789 with @entity625 or @entity4790 . The prognosis of such @entity1 with @entity4789 and @entity4092 is critical when determining the duration of antibiotic prophylaxis. We aimed, therefore, prospectively to investigate the association of silent valvitis in @entity1 having @entity4789 in the absence of clinical evidence of cardiac involvement, and to evaluate its prognosis. METHODS AND RESULTS: Between November 1998 and September 1999, we identified 26 consecutive @entity1 with silent valvitis in presence of @entity4789 but in the absence of clinical signs of @entity2401 . The @entity1 , eight female and 18 male, were aged from 6 to 16 years, with a mean of 9.9+/-2.7 years. Major findings were @entity625 in 16, @entity4790 in 7, and @entity625 and @entity5105 in 1 @entity1 . Two cases had @entity4841 with equivocal arthritic signs and Doppler echocardiographic findings of pathologic @entity339 . Silent pathologic @entity339 was found in 12 cases, and @entity337 in 2 cases. All @entity1 with arthritic findings were treated with @entity117 with one exception, this @entity1 receiving both @entity229 and @entity117 . No antiinflammatory treatment was given to @entity1 with @entity4790 . After a mean follow-up of 4.52 months, @entity338 disappeared in 4 @entity1 , including the one with @entity4841 and no other major criterions. All six @entity1 with @entity4790 and silent @entity2401 still have @entity339 . CONCLUSION: Acute @entity4789 without clinical @entity2401 is not a benign entity. Doppler echocardiographic findings of subclinical @entity1887 , therefore, should be considered as @entity2401 when seeking to establish the diagnosis of @entity4789 .

Can @entity4092 detected by echocardiography be accepted as evidence of @entity2401 in the diagnosis of XXXX ?

@entity4789 :: ('MESH:D012213', 'Disease') :: ['rheumatic fever', 'acute rheumatic fever'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral regurgitation', 'mitral insufficiency'] @entity625 :: ('MESH:D001168', 'Disease') :: ['arthritis', 'isolated arthritis'] @entity4790 :: ('MESH:D002819', 'Disease') :: ['chorea'] @entity1887 :: ('MESH:D000309', 'Disease') :: ['valvar insufficiency', 'Subclinical valvar insufficiency'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['acetylsalicylic acid'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity338 :: ('MESH:D011665', 'Disease') :: ['valvar regurgitation'] @entity5105 :: ('MESH:D004890', 'Disease') :: ['erythema marginatum'] @entity337 :: ('MESH:D001022', 'Disease') :: ['aortic regurgitation'] @entity4841 :: ('MESH:D018771', 'Disease') :: ['arthralgia', 'migratory arthralgia'] @entity2401 :: ('MESH:D009205', 'Disease') :: ['carditis'] @entity4092 :: ('MESH:D058345', 'Disease') :: ['subclinical valvitis']
@entity4789 :: (MESH:D012213,Disease) :: ['acute rheumatic fever']
