Biomechanical factors play an important role in @entity6 . Reducing high foot pressures (i.e. offloading) is one of the main goals in healing and preventing foot ulceration. Evidence-based guidelines show the strong association between the efficacy to offload the foot and clinical outcome. However, several aspects related to offloading are underexposed. First, in the management of foot complications, offloading is mostly studied as a single entity, whereas it should be analysed in a broader perspective of contributing factors to better predict clinical outcome. This includes assessment of @entity1 behavioural factors such as type and intensity of daily physical activity and adherence to prescribed treatment. Second, a large gap exists between evidence-based recommendations and clinical practice in the use of offloading for @entity1066 treatment, and this gap needs to be bridged. Possible ways to achieve this are discussed in this article. Third, our knowledge about the efficacy and role of offloading in treating complicated and non-plantar @entity1411 needs to be expanded because these @entity1066 currently dominate presentation in multidisciplinary foot practice. Finally, foot @entity1066 prevention is underexposed when compared with @entity1066 treatment. Prevention requires a larger focus, in particular regarding the efficacy of therapeutic footwear and its relative role in comparison with other preventative strategies. These priorities need the attention of clinicians, scientists and professional societies to improve our understanding of offloading and to improve clinical outcome in the management of the @entity6 foot.

Priorities in offloading the XXXX foot.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer', 'ulcers'] @entity1411 :: ('MESH:D016523', 'Disease') :: ['neuropathic foot ulcers'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic', 'diabetic foot disease']
@entity6 :: (MESH:D003920,Disease) :: ['diabetic']
