We have analyzed paraffin sections from 32 @entity1 with histologically confirmed @entity2109 ( @entity2109 ) for the presence of EBV using in situ hybridization to detect expression of the EBV-encoded early RNAs (EBERs). EBV was present in the @entity5 of 11 @entity1 (34%). Sixty nine percent of the @entity1 presented with abdominal disease, 19% had @entity236 and only one @entity1 had jaw involvement. There was no statistically significant difference between EBV positive and EBV negative @entity1 with regard to age, gender, origin, primary site at presentation, or clinical stage of disease. However, there was a trend for younger age in the @entity1 with EBV positive @entity2109 with a median age of 4, compared to 7 years in @entity1 with EBV negative @entity2109 . None of the 7 @entity1 of Ashkenazi Jewish origin had EBER positive disease. There was no difference in the treatment outcome between the EBV positive @entity1 (estimated survival at 24 months of 82%) and EBV negative @entity1 (estimated survival rate of 71% (p=0.58)). In conclusion, although this is only a small series it seems that childhood @entity2109 in Israel has the clinical characteristics of sporadic, non-African type with 34% EBV association and a low incidence of @entity14318 . Our data suggest that Ashkenazi Jewish @entity1 with @entity2109 are less likely to have EBV positive @entity5 than other ethnic groups. However, more @entity1 will need to be studied in order to assess the validity of this observation.

Expression of EBV encoded nuclear small non-polyadenylated RNA (EBER) molecules in 32 cases of childhood XXXX from Israel.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'child'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity2109 :: ('MESH:D002051', 'Disease') :: ["Burkitt's Lymphoma", 'BL'] @entity14318 :: ('MESH:D007573', 'Disease') :: ['jaw tumors'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow infiltration']
@entity2109 :: (MESH:D002051,Disease) :: ['Burkitt's lymphoma']
