OBJECTIVE: The results of primary surgery for @entity1149 ( @entity1149 ) with involved ipsilateral mediastinal or subcarinal lymph nodes (N2 disease) remains poor. However, several studies suggest that induction chemotherapy could increase long-term survival in @entity1 with N2 disease. Therefore, accurate preoperative staging of the mediastinum remains of paramount importance for the treatment policy in @entity1 with @entity1149 . Enlarged @entity1600 ( @entity1600 ) on CT scan are positive in only half of the @entity1 . Small lymph nodes can contain metastatic deposits of clinical importance. However, many surgeons believe that a normal mediastinum at computed tomography allows them to cancel their preoperative mediastinal exploration. It was the aim of this study to evaluate the results of cervical mediastinoscopy in @entity1 without enlarged @entity1600 on CT scan. METHODS: Between January 1990 and June 1994, 235 @entity1 with potentially operable @entity1149 underwent a cervical mediastinoscopy despite the absence of enlarged @entity1600 on CT scan. @entity1600 were considered enlarged if they were equal to or larger than 15 mm at their maximal cross-sectional diameter. RESULTS: Cervical mediastinoscopy was positive in 47 @entity1 (20%). In 21 @entity1 , N2 disease was extranodal and in 16 @entity1 more than one level was involved. Mediastinoscopy was positive in 9.5% of the cT1N0 cases, in 17.7% of the cT2N0 lesions, in 31.2 and 33.3% of cT3N0 or cT4N0 @entity5 , respectively. After a negative cervical mediastinoscopy, resectability for unforeseen N2 disease was as high as 95%. CONCLUSION: We recommend a cervical mediastinoscopy in every @entity1 with potentially operable @entity1149 .

Role of cervical mediastinoscopy in staging of @entity1149 without enlarged XXXX on CT scan.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small cell lung cancer'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['mediastinal lymph nodes', 'MLN'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors']
@entity1600 :: (MESH:D014388,Disease) :: ['mediastinal lymph nodes']
