PURPOSE: @entity299 risk is elevated in South Asians possibly due to impaired postprandial metabolism. Running has been shown to induce @entity4053 in South Asian than European @entity1 , but the effect of walking in South Asians is unknown. METHODS: Fifteen South Asian and 14 white European @entity1 aged 19-30  years completed two, 2-day trials in a randomised crossover design. On day 1, @entity1 rested (control) or walked for 60  min at approximately 50  % maximum @entity26 uptake (exercise). On day 2, @entity1 rested and consumed two high-fat meals over a 9-h period during which 14 venous blood samples were collected. RESULTS: South Asians exhibited higher postprandial @entity1674 [geometric mean (95  % confidence interval) 2.29 (1.82 to 2.89) vs. 1.54 (1.21 to 1.96) mmol  L(-1)  h(-1)], @entity413 [5.49 (5.21 to 5.79) vs. 5.05 (4.78 to 5.33) mmol  L(-1)  h(-1)], insulin [32.9 (25.7 to 42.1) vs. 18.3 (14.2 to 23.7)   U  mL(-1)  h(-1)] and @entity650 [2.44 (1.61 to 3.67) vs. 1.04 (0.68 to 1.59) pg  mL(-1)  h(-1)] than Europeans (all ES >=   0.72, P   <=  0.03). Between-group differences in @entity1674 , @entity413 and insulin were not significant after controlling for age and percentage body fat. Walking reduced postprandial @entity1674 [1.79 (1.52 to 2.12) vs. 1.97 (1.67 to 2.33) mmol  L(-1)  h(-1)] and insulin [21.0 (17.0 to 26.0) vs. 28.7 (23.2 to 35.4)   U  mL(-1)  h(-1)] (all ES >=   0.23. P   <=  0.01), but group differences were not significant. CONCLUSIONS: Healthy South Asians exhibited impaired postprandial metabolism compared with white Europeans, but these differences were diminished after controlling for potential confounders. The small-moderate reduction in postprandial @entity1674 and insulin after brisk walking was not different between the ethnicities.

The effect of prior walking on coronary heart disease risk markers in South Asian and European XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'men'] @entity650 :: ('3569', 'Gene') :: ['interleukin-6'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triacylglycerol'] @entity4053 :: ('MESH:D007003', 'Disease') :: ['greater reductions in postprandial lipaemia'] @entity299 :: ('MESH:D006331', 'Disease') :: ['Heart disease'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity1 :: (9606,Species) :: ['men']
