@entity149 ( @entity149 ) is usually diffuse large @entity1892 . @entity2108 ( @entity2108 ) rarely occurs in the central nervous system. @entity149 always presents as single or multiple nodular contrast-enhancing mass lesions within T2-hyperintense areas on magnetic resonance imaging (MRI). Infrequently, diffuse infiltrating change with little contrast enhancement called lymphomatosis cerebri can be seen in @entity149 . In this report, we describe a 75-year-old immunocompetent @entity1 who had progressive @entity303 . On MRI, diffuse white matter lesions with little contrast enhancement were observed to gradually progress, which was clinically consistent with his worsening condition. A biopsy specimen revealed non-destructive, diffusely infiltrating, anaplastic large @entity5823 -positive @entity706 , indicating a diagnosis of @entity2108 . After the biopsy, he was treated by whole brain irradiation (total 46  Gy) and focal boost irradiation (total 14  Gy). However, his performance status worsened and there was no symptom improvement. The @entity1 died 8  months after symptom onset. The clinical course, diagnostic workup, pathologic correlates, and treatment outcomes are described herein.

Primary central nervous system anaplastic large-cell XXXX mimicking lymphomatosis cerebri.

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity149 :: ('MESH:D002493', 'Disease') :: ['PCNSL', 'Primary central nervous system lymphoma'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['B-cell lymphoma'] @entity5823 :: ('943', 'Gene') :: ['CD30'] @entity2108 :: ('MESH:D017728', 'Disease') :: ['Anaplastic large-cell lymphoma', 'ALCL']
@entity706 :: (MESH:D008223,Disease) :: ['lymphoma']
