UNASSIGNED: The occurrence of @entity7893 ( @entity7893 ) after chemo-immunotherapy represents a potential side effect in @entity1 with indolent @entity1893 (iNHL). Few data are available on @entity7893 occurring after chemotherapy and/or Rituximab (R). We retrospectively investigated the incidence and the risk factors for @entity7893 and @entity166 in @entity1 with iNHL after chemo-immunotherapy. Two hundred and sixty six @entity1 treated between 1993 and 2011 were studied. @entity1 with a @entity5702 or a monoclonal component were excluded. The incidence of @entity7893 was 2.2*1000 @entity1 -years (95% CI 1.6-2.9). Exposure to @entity3118 -based schedules (Fbs)  R was associated with a hazard ratio (HR) of 18.1 (95% CI: 4.3-77.0). Conversely, exposure to CHOP  R or CVP  R was not a risk factor (HR 0.3, 95% CI: 0.1-0.8; HR 0.3, 95% CI: 0.08-1.4, respectively). The role of R was studied comparing cohorts differing only for R; no differences were found comparing R-CHOP/R-CVP versus CHOP/CVP (HR 1.07, 95% CI: 0.38-3.05) and R-Fbs versus Fbs (HR 2.07, 95% CI: 0.62-6.99). Autologous stem cell transplantation (ASCT) is also a risk factor (HR: 5.2, 95% CI 2.1-13.0). @entity7893 @entity1 presented a high risk for @entity55 development (HR 7.07 95% CI: 2.68-18.44). We recommend monitoring of serum immunoglobulins in an attempt to reduce the probability of infection after Fbs or ASCT.

Risk of secondary hypogammaglobulinaemia after Rituximab and @entity3118 in indolent XXXX : A retrospective cohort study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'person'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity3118 :: ('MESH:C024352', 'Chemical') :: ['Fludarabine'] @entity5702 :: ('MESH:D018295', 'Disease') :: ['basal hypogammaglobulinemia'] @entity7893 :: ('MESH:D000361', 'Disease') :: ['secondary hypogammaglobulinemia', 'SH'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['non-Hodgkin lymphomas'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious complications']
@entity1893 :: (MESH:D008228,Disease) :: ['non-Hodgkin lymphomas']
