BACKGROUND: Harm reduction is an evidence-based, effective response to @entity645 transmission and other harms faced by @entity1 who inject drugs, and is explicitly supported by the Global Fund to Fight @entity791 , @entity378 and @entity311 . In spite of this, @entity1 who inject drugs continue to have poor and inequitable access to these services and face widespread stigma and discrimination. In 2013, the Global Fund launched a new funding model-signalling the end of the previous rounds-based model that had operated since its founding in 2002. This study updates previous analyses to assess Global Fund investments in harm reduction interventions for the duration of the rounds-based model, from 2002 to 2014. METHODS: Global Fund @entity645 and @entity1906 / @entity645 grant documents from 2002 to 2014 were reviewed to identify grants that contained activities for @entity1 who inject drugs. Data were collected from detailed grant budgets, and relevant budget lines were recorded and analysed to determine the resources allocated to different interventions that were specifically targeted at @entity1 who inject drugs. RESULTS: 151 grants for 58 countries, plus one regional proposal, contained activities targeting @entity1 who inject drugs-for a total investment of @entity10479  620million. Two-thirds of this budgeted amount was for interventions in the "comprehensive package" defined by the United Nations. 91% of the identified amount was for Eastern Europe and Asia. CONCLUSION: This study represents an updated, comprehensive assessment of Global Fund investments in harm reduction from its founding (2002) until the start of the new funding model (2014). It also highlights the overall shortfall of harm reduction funding, with the estimated global need being @entity10479  2.3billion for harm reduction in 2015 alone. Using this baseline, the Global Fund must carefully monitor its new funding model and ensure that investments in harm reduction are maintained or scaled-up. There are widespread concerns regarding the withdrawal from middle-income countries where harm reduction remains essential and unfunded through other sources: for example, 15% of the identified investments were for countries which are now ineligible for Global Fund support.

The Global Fund to Fight XXXX , @entity378 and @entity311 's investments in harm reduction through the rounds-based funding model (2002-2014).

@entity1 :: ('9606', 'Species') :: ['people'] @entity10479 :: ('MESH:D065309', 'Disease') :: ['US'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity1906 :: ('MESH:D014390', 'Disease') :: ['TB'] @entity311 :: ('MESH:D008288', 'Disease') :: ['Malaria'] @entity378 :: ('MESH:D014376', 'Disease') :: ['Tuberculosis'] @entity791 :: ('MESH:D000163', 'Disease') :: ['AIDS']
@entity791 :: (MESH:D000163,Disease) :: ['AIDS']
