Ninety-four @entity1 with classical @entity814 are reviewed. Early treatment with a low @entity815 diet usually results in normal or near-normal I.Q. Twenty-seven of the 38 @entity1 diagnosed before 2 months of age have an I.Q. in the normal range. Of the other 11, six are dull normal, four are borderline and one is @entity1032 . Adequate reasons are given for the less than optimal results in these 11 early-treated @entity1 . Twenty-one of the 28 @entity1 presenting with abnormal electroencephalograms showed normal tracings soon after initiation of diet and four of the other seven improved. Nine of 12 on continuous anticonvulsant medication at the time of presentation were able to discontinue this soon after institution of dietary measures. Eighteen of the 19 sibling pair comparisons revealed a better ultimate I.Q. in the early-treated sib. A plea for early diagnosis by continuation of newborn screening programs and for centralization of diagnostic confirmation and treatment is made.

The efficacy of dietary therapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['frankly retarded'] @entity815 :: ('CHEBI:28044', 'Chemical') :: ['phenylalanine'] @entity814 :: ('MESH:D010661', 'Disease') :: ['phenylketonuria']
@entity814 :: (MESH:D010661,Disease) :: ['phenylketonuria']
