OBJECTIVES: Although laparoscopic posterior fundoplication (LPF) i.e., Nissen or Toupet have the proven efficacy for controlling gastro-esophageal reflux surgically, there remain problems with postoperative @entity1282 and @entity11035 . To decrease some of these @entity260 , laparoscopic anterior fundoplication (LAF) was introduced. The aim of this study was to conduct a meta-analysis and systematic review of randomized controlled trials (RCTs) to investigate the merits and drawbacks of LPF versus LAF for the treatment of @entity354 ( @entity354 ). DATA SOURCES, STUDY SELECTION, AND REVIEW METHODS: A search of Medline, Embase, Science Citation Index, Current Contents, PubMed, ISI Web of Science, and the Cochrane Database identified all RCTs comparing different types of LPF and LAF published in the English Language between 1990 and 2013. The meta-analysis was prepared in accordance with the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) statement. Data was extracted and analyzed on ten variables which include @entity1282 score, heartburn rate, redo operative rate, operative time, overall complications, rate of conversion to open, Visick grading of satisfaction, overall satisfaction, length of hospital stay, and postoperative 24-h pH scores. DATA SYNTHESIS: Nine trials totaling 840 @entity1 (anterior  =  425, posterior  =  415) were analyzed. There was a significant reduction in the odds ratio for @entity1282 in the LAF group compared to the  LPF group. Conversely, significant reduction in the odds ratio for heartburn was observed for LPF compared to LAF. Comparable effects were noted for both groups for other variables which include redo surgery, operating time, overall complications, conversion rate, Visick's grading, @entity1 ' satisfaction, length of hospital stay, and postoperative 24-h pH scores. CONCLUSIONS: Based on this meta-analysis, LPF compared to LAF is associated with significant reduction in heartburn at the expense of higher @entity1282 rate on a short- and medium-term basis. We therefore conclude that LPF is a better alternative to LAF for controlling @entity354 symptoms.

Laparoscopic Anterior Versus Posterior Fundoplication for XXXX : A Meta-analysis and Systematic Review.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity11035 :: ('MESH:C535647', 'Disease') :: ['gas bloat syndrome'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastro-esophageal reflux disease', 'GERD'] @entity1282 :: ('MESH:D003680', 'Disease') :: ['dysphagia']
@entity354 :: (MESH:D005764,Disease) :: ['Gastro-esophageal Reflux Disease']
