AIM: @entity2012 is a @entity102 characterized by enhanced @entity2124 ( @entity2124 ) secretion and elevated @entity442 ( @entity442 ) levels, usually caused by @entity977 . In this retrospective study, we reviewed our experience with endoscopic endonasal transsphenoidal surgery (EETS) with in remission rates using the 2010 consensus criteria, predictors of remission and associated complications. MATERIAL AND METHODS: The authors retrospectively analyzed data from 56 acromegalic @entity1 who underwent pure EETS. @entity5 were classified according to size and suprasellar/parasellar extension. The criteria of remission were @entity2124 levels < 1 ng/mL randomly, < 0.4 ng/mL after oral @entity413 tolerance test and normal @entity442 levels for age and sex within the first 3 and 6 months after surgery. RESULTS: Biochemical remission was achieved in 4 of 5 microadenomas (80%) and in 33 of 51 macroadenomas (64.7%). The total remission rate was 66.1% (37 of 56 @entity652 ). Age, gender and suprasellar extension did not affect the remission rate. However, cavernous sinus invasion, sphenoid sinus invasion and history of prior surgery were associated with lower rates of disease control. CONCLUSION: EETS represents an effective and safe option for the treatment of @entity1 with @entity2012 . High disease control rates and a small number of complications are some of the most important points related to the technique.

Endoscopic endonasal transsphenoidal treatment for XXXX : 2010 consensus criteria for remission and predictors of outcomes.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Tumors'] @entity442 :: ('3479', 'Gene') :: ['insulin-like growth factor-I', 'IGF-I'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic disorder'] @entity2124 :: ('2688', 'Gene') :: ['GH', 'growth hormone'] @entity2012 :: ('MESH:D000172', 'Disease') :: ['acromegaly', 'Acromegaly'] @entity977 :: ('MESH:D010911', 'Disease') :: ['pituitary adenomas'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity2012 :: (MESH:D000172,Disease) :: ['acromegaly']
