BACKGROUND: Although China is the most coveted cigarette market worldwide, few studies have examined the longitudinal effects of environmental @entity286 smoke (ETS) on health. PURPOSE: To examine the relationship between exposure to ETS and respiratory health in Chinese schoolchildren. METHODS: The study subjects included 1718 @entity1 , who were never-smokers, aged 10.05  0.86 years and @entity565 -free at baseline. The @entity1 performed spirometric tests in 2006 and 18 months later. Parents reported the @entity1 's respiratory symptoms and illnesses, ETS exposure, and other related information by self-administered survey at both assessment points. The data were analyzed in 2010. RESULTS: Significant exposure-response relationships were found between ETS exposure and coughing at night (p for trend<0.001); sneezing (p for trend=0.031); and sneezing with itchy, @entity735 (p for trend=0.006) in the first survey, and coughing at night (p for trend=0.019); phlegm without a cold (p for trend<0.001); and sneezing (p for trend=0.036) in the second survey. Compared with those who reported no ETS exposure in either survey, @entity1 who had a high ETS exposure level (>5 cigarettes/day) in either survey had lower growth rates in forced expiratory flow between 25% and 75% of forced vital capacity (FEF(25-75); b= -0.104, p=0.020) and forced expiratory flow at 25% of forced vital capacity (FEF(25); b= -0.077, p=0.027). A monotonic exposure-response effect was observed between ETS exposure and the deficits in the growth rate of FEF(25) and FEF(25-75.) CONCLUSIONS: Exposure to ETS increased the risks of respiratory symptoms in Chinese school-aged @entity1 and was associated with @entity73 growth. A dose-response relationship was observed for the latter effect.

Environmental XXXX smoke exposure and Chinese schoolchildren's respiratory health: a prospective cohort study.

@entity1 :: ('9606', 'Species') :: ['children'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impaired lung function'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity735 :: ('MESH:D005124', 'Disease') :: ['watery eyes']
@entity286 :: (4097,Species) :: ['tobacco']
