We prospectively included in a database all thrombolyzed acute transmural @entity583 @entity1 admitted to our hospital from November 1986 to September 1995. Six hundred and twenty-seven @entity1 (497 males) with a mean age of 61 +/- 12 years (range 26-88 years) were included. 87% were having their first acute @entity583 . Different thrombolytic regimens were applied in the emergency room but the vast majority (92%) received @entity3479 . The median delay between the onset of @entity158 and admission was 2 h 0 min (10 min-22 h). The median admission to treatment time was 40 min (5 min-6 h 20 min). The latter has been shortened (median 55 min from 1986 to 1989 versus 35 min from 1990 to 1995, p < 0.05) during the study period. The rate of @entity1779 was 2.4% (confidence interval 1.1-3.5%) and no significant predictor could be found, although @entity1 with @entity1779 tended to be slightly older (66 +/- 9 years vs 61 +/- 13 years, p = ns). The rate of false diagnosis was only 4.6%, even when @entity1 with a final diagnosis of @entity583 were included. The in-hospital mortality was 8.8%, a rate similar to those reported in the literature. Using multivariate analysis, negative prognostic factors were higher age (p < 0.001), advanced Killip class at admission (p < 0.001) and elevated peak @entity9153 levels (p < 0.001). These results confirm that thrombolysis for acute @entity583 in the emergency room can be done with a short admission-to-treatment time and with an acceptably low rate of false diagnosis. However, our @entity1779 rate was clearly higher than generally reported in the literature and may be explained by a different @entity1 selection from that in large randomized studies.

[Thrombolysis in acute XXXX in everyday clinical practice].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'unstable angina and/or aborted acute myocardial infarction'] @entity3479 :: ('5327', 'Gene') :: ['t-PA'] @entity9153 :: ('5286', 'Gene') :: ['CPK'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['cerebral bleeding', 'intracerebral hemorrhage']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarct']
