PURPOSE: To determine the feasibility of diffusion-tensor imaging (DTI) and tractography as means of evaluating the depth of mural invasion by @entity356 . MATERIALS AND METHODS: This study was approved by our institutional review board, and written informed consent was obtained from each @entity1 . Twenty gastric specimens containing a @entity189 were studied with a 7.0-T MR imaging system equipped with a four-channel phased-array surface coil. DTI was performed by using a field of view of 50-60 mm x 25-30 mm, matrix of 256 x 128, section thickness of 1 mm, b value of 1000 sec/mm(2), and motion-probing gradients in seven noncollinear directions. The MR images were compared with the histopathologic findings as the reference standard. RESULTS: In all 20 @entity189 (100%) the diffusion-weighted images, apparent diffusion coefficient (ADC) maps, fractional anisotropy (FA) maps,   1 maps, and direction-encoded color FA maps made it possible to identify the same depth of @entity5 invasion of the gastric wall as observed during histopathologic examination. The   1 maps provided the best contrast between the @entity189 and the layers of the gastric wall. The @entity189 also had lower ADC values and lower FA values than the normal gastric wall; thus, the @entity189 were clearly demarcated from the normal gastric wall. Tractography images were also useful for determining the depth of @entity5 invasion of the gastric wall. CONCLUSIONS: DTI and tractography are feasible means of evaluating gastric specimens and provide excellent diagnostic accuracy for evaluating mural invasion by @entity356 .

XXXX : evaluation with diffusion-tensor MR imaging and tractography ex vivo.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas', 'carcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric carcinomas']
@entity356 :: (MESH:D013274,Disease) :: ['Gastric carcinoma']
