BACKGROUND: The incidence of @entity7172 ( @entity7172 ) of the thyroid is rapidly increasing globally, making the management of @entity7172 an important clinical issue. Excellent oncological outcomes of active surveillance for low-risk @entity7172 have been reported previously. Here, unfavorable events following active surveillance and surgical treatment for @entity7172 were studied. METHODS: From February 2005 to August 2013, 2153 @entity1 were diagnosed with low-risk @entity7172 . Of these, 1179 @entity1 chose active surveillance and 974 @entity1 chose immediate surgery. The oncological outcomes and the incidences of unfavorable events of these groups were analyzed. RESULTS: In the active surveillance group, 94 @entity1 underwent surgery for various reasons; @entity5 enlargement and the appearance of novel lymph node @entity3 were the reasons in 27 (2.3%) and six @entity1 (0.5%), respectively. One of the @entity1 with conversion to surgery had nodal recurrence, and five @entity1 in the immediate surgery group had a recurrence in a cervical node or unresected thyroid lobe. All of these recurrences were successfully treated. None of the @entity1 had distant @entity3 , and none died of the disease. The immediate surgery group had significantly higher incidences of transient @entity3746 ( @entity3746 ), @entity261 , and permanent @entity261 than the active-surveillance group did (4.1% vs. 0.6%, p   <   0.0001; 16.7% vs. 2.8%, p   <   0.0001; and 1.6% vs. 0.08%, p   <   0.0001, respectively). Permanent @entity3746 occurred only in two @entity1 (0.2%) in the immediate surgery group. The proportion of @entity1 on @entity1955 for supplemental or thyrotropin (TSH)-suppressive purposes was significantly larger in the immediate surgery group than in the active surveillance group (66.1% vs. 20.7%, p   <   0.0001). The immediate surgery group had significantly higher incidences of postsurgical @entity1410 and surgical scar in the neck compared with the active surveillance group (0.5% vs. 0%, p   <   0.05; and 8.0% vs. 100%, p   <   0.0001, respectively). CONCLUSIONS: The oncological outcomes of the immediate surgery and active surveillance groups were similarly excellent, but the incidences of unfavorable events were definitely higher in the immediate surgery group. Thus, active surveillance is now recommended as the best choice for @entity1 with low-risk @entity7172 .

Incidences of Unfavorable Events in the Management of Low-Risk XXXX of the Thyroid by Active Surveillance Versus Immediate Surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1955 :: ('MESH:D013974', 'Chemical') :: ['L-thyroxine'] @entity261 :: ('MESH:D007011', 'Disease') :: ['transient hypoparathyroidism', 'hypoparathyroidism'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity7172 :: ('MESH:C563277', 'Disease') :: ['papillary microcarcinoma', 'PMC'] @entity3746 :: ('MESH:D014826', 'Disease') :: ['VCP', 'vocal cord paralysis']
@entity7172 :: (MESH:C563277,Disease) :: ['Papillary Microcarcinoma']
