Conventional resting echocardiography is not able to predict contractile reserve (CR) of @entity1 with @entity1000 . The aim of this study was to investigate whether the videodensitometric myocardial texture analysis could predict the CR of these @entity1 . Myocardial texture analysis was performed on echocardiographic digitized images of 27 @entity1 with IDC through a calibrated 256 gray level digitization system. Cyclic variation (CV) index of myocardial mean gray level (MGL) was calculated according to the formula: (MGL(diast) - MGL(syst))/ MGL(diast) x 100. CR was defined as the %-change of ejection fraction by 10 microg/kg per minute @entity452 infusion. A clinical follow-up was also performed for all @entity1 for an average of 8 +/- 3 months. CR ranged from -1.8% to 50.3%. CV index of both septum and posterior wall (PW) was the single parameter significantly correlated to CR (r = 0.69 and r = 0.77, respectively, P <.0001 for both). The mean resting CV index of septum and PW were significantly lower in @entity1 with CR less than 17%-median value of all subjects-(5.7 +/- 5.6 vs 16.9 +/- 7.9 and 5.4 +/- 5.9 vs 16.1 +/- 6.4, respectively, P <.0001 for both). A CV index of 10% for both septum and PW yielded a sensitivity of 77% and 84%, and a specificity of 84% and 84% for predicting diminished CR, respectively. The event-free survival rate was significantly lower in @entity1 with CR less than 17% (61.5% vs 92.8%, P <.05). The CV index of both septum and PW were also significantly lower in @entity1 with @entity299 (13.6 +/- 8 vs 4.3 +/- 6, P <.05 and 14.7 +/- 7 vs 4.1 +/- 7, P <.01, respectively). Ultrasonic myocardial texture analysis in @entity1000 has a high ability to discriminate the @entity1 with and without preserved CR, and @entity1 with unfavorable outcome as well.

Myocardial texture analysis in @entity1000 : prediction of contractile reserve on XXXX echocardiography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1000 :: ('MESH:C536277', 'Disease') :: ['idiopathic dilated cardiomyopathy'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['dobutamine'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events']
@entity452 :: (MESH:D004280,Chemical) :: ['dobutamine']
