BACKGROUND: Individuals who die from suicide commonly have consumed @entity167 immediately beforehand, often in large quantities. However, prospective cohort data on regular @entity167 use as a risk factor for suicide are lacking. METHOD: As part of the Health Professionals Follow-up Study, 47,654 @entity1 free of @entity5 prospectively reported their drinking habits, including average use, drinking frequency, and typical maximal use on repeated occasions beginning in 1986. @entity1 were followed for @entity204 to 2002. RESULTS: A total of 136 @entity1 died from suicide during follow-up. Quantity of @entity167 consumed per drinking day tended to be associated with a greater risk of suicide mortality, with an adjusted hazard ratio among @entity1 consuming 30.0 or more grams (more than two drinks) per drinking day of 2.42 (95% confidence interval, 0.75-7.80; P-trend 0.05). Average @entity167 consumption, drinking frequency, and binge drinking were not independently associated with risk. The apparent relationship of quantity consumed per drinking day with risk was not substantially changed by adjustment for serious illness or other dietary factors and was most notable for suicide associated with firearm use. CONCLUSIONS: Among @entity1 , risk of @entity204 from suicide tends to be associated primarily with quantity of @entity167 consumed per drinking day, not with drinking frequency or overall @entity167 consumption. This finding supports guidelines that limit consumption among @entity1 who choose to drink @entity167 to two drinks or less per drinking day.

Drinking frequency and quantity and risk of suicide among XXXX .

@entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity1 :: ('9606', 'Species') :: ['Participants', 'men'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer']
@entity1 :: (9606,Species) :: ['men']
