OBJECTIVE: Indications for @entity1164 ( @entity1164 ) primary prevention are unknown in @entity1 with repaired tetralogy of Fallot (ToF). The role of microvolt T-wave alternans (MTWA) in @entity1164 risk stratification was documented. However, the prevalence of spectral MTWA and its association with @entity943 ( @entity943 ) in adults after ToF repair were not elucidated. DESIGN: Microvolt T-wave alternans, electrocardiogram (ECG), ambulatory ECG monitoring, echocardiography, and spiroergometry were evaluated in 102 adults after ToF repair. Microvolt T-wave alternans results were classified as normal: negative(-), abnormal: positive(+), and indeterminate(ind). Owing to similar prognostic significance, MTWA(+) and MTWA(ind) due to @entity1 factors were combined into nonnegative group: MTWA(abnormal). RESULTS: Microvolt T-wave alternans(abnormal) was more frequent in the studied group as compared with controls (P = .0005). The MTWA(abnormal) group had greater right ventricular end-diastolic diameter (P = .005), higher incidence of @entity338 (P = .015), lower peak @entity26 consumption (P = .01), and higher VE/VCO2 slope (P = .04) in comparison with MTWA(normal). Univariate logistic regression proved @entity338 (OR = 3.57, 95% CI 1.27-10.04), @entity943 (OR = 3.26, 95% CI 1.06-10.05), right ventricular end-diastolic enlargement (OR = 1.11, 95% CI 1.03-1.2), increase in VE/VCO2 slope (OR = 1.08, 95% CI 1.01-1.17), and decrease in peak @entity26 uptake (OR = .91, 95% CI 0.83-0.99) to increase MTWA(abnormal) prevalence. CONCLUSIONS: In adults after ToF repair, abnormal MTWA occurred more often than in controls. Probability of abnormal MTWA did not rise with prevalence of malignant @entity943 ; however, presence of abnormal MTWA was associated with @entity943 risk factors: @entity338 , @entity4266 , and consequent @entity712 . The role of MTWA in selecting @entity1 late after ToF repair at risk of @entity1164 needs further observation.

Microvolt T-wave Alternans in Adult XXXX with Repaired Tetralogy of Fallot.

@entity1164 :: ('MESH:D016757', 'Disease') :: ['sudden cardiac death', 'SCD'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity338 :: ('MESH:D011665', 'Disease') :: ['pulmonary regurgitation'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmia', 'VA'] @entity4266 :: ('MESH:D018497', 'Disease') :: ['right ventricular enlargement']
@entity1 :: (9606,Species) :: ['Patients']
