BACKGROUND/AIMS: The aim of this retrospective study was to analyse the characteristics, treatment and prognosis of early @entity356 , based on an analysis of our surgical results. METHODOLOGY: Between 1973 and 1994, 102 @entity1 (68 males, 34 females) with a mean age of 65 years, were operated on for an early @entity356 . Mean follow-up was 7 years. Survival was calculated using the Kaplan-Meier method. Prognosis was determined with univariate and multivariate analysis according to the Cox model. RESULTS: The @entity189 was limited to the mucosa in 57 @entity1 (56%) and extended to the submucosa in 45 (44%). There was a lymph node invasion in 17 @entity1 (16.5%). The post-operative mortality rate was 5.8% (n = 6). Secondary deaths occurred in relation with the @entity356 in 10.4% (n = 10). The 5- and 10-year survival rates were 84% and 68.6%, respectively. Univariate analysis of prognosis factors showed a significant survival difference according to the age (p = 0.001); submucosal extension (p = 0.03), lymph node invasion (p = 0.0005) and type of gastric resection performed (p = 0.03). With multivariate analysis of prognostic factors, advanced @entity1 age and lymph node @entity3 were the only independent factors for survival (p = 0.0002 and p = 0.002, respectively). CONCLUSIONS: Prognosis of early @entity356 is usually excellent. @entity1 with high risk of recurrence may be identified in relation to lymph node invasion. We propose that lymph node dissection is necessary in addition to gastric resection, at least in @entity1 with high risk of lymph node @entity3 .

Early XXXX : univariate and multivariate analysis for survival.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'gastric carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
