@entity27 ( @entity27 ) is associated with @entity6 , @entity101 , @entity64 , @entity453 , and @entity204 . Positive airway pressure ( @entity2786 ) is the mainstay of therapy. Despite its effective treatment with @entity2786 therapy, noncompliance remains high. Many factors determine compliance. The role of severity of @entity27 measured by the @entity27 index (AHI) remains controversial. Meta-analysis of studies examining this role of AHI was performed. A systematic review of the medical literature was conducted using PubMed and Cochrane library by utilizing different combinations of key words: sleep @entity386 , AHI, compliance, and nonadherence. Inclusion criteria were English articles; Studies with adult population; with 2 groups of @entity1 (compliant and noncompliant); Studies utilizing objective definition of compliance ( @entity2786 usage of >4 hours per night for 70% of days or usage >5 d/wk and for >4 hours per night). Studies were analyzed by standard methods of meta-analysis. The studies were heterogeneous for AHI; therefore, the random effect model was used. Six hundred forty-one manuscripts were found. Of these, 230 were found to be appropriate for full text evaluation. Thirty-one met inclusion criteria. Twelve of these studies used objective criteria for @entity2786 compliance and were hence included in meta-analysis. All the subjects had @entity27 determined by polysomnography, for whom @entity2786 was employed. Compliance to @entity2786 therapy was evaluated after a period of time ranging from 4 weeks to 8 years. There were 1438 subjects included in the meta-analysis; 886 subjects were @entity2786 compliant, whereas 552 subjects were noncompliant. A greater AHI was found in @entity2786 compliant @entity1 . The mean difference between compliant and noncompliant groups was 5.9 (95% confidence interval: 0.19-11.67, P < 0.05). @entity1 with mild @entity27 are less likely to be compliant with @entity2786 therapy. These @entity1 should receive aggressive management particularly at the start of therapy with close follow-up to increase compliance.

The role of severity of XXXX measured by @entity27 index in predicting compliance with pressure therapy, a meta-analysis.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity27 :: ('MESH:D020181', 'Disease') :: ['apnea-hypopnea', 'Obstructive sleep apnea', 'OSA'] @entity2786 :: ('CHEBI:17985', 'Chemical') :: ['PAP'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity204 :: ('MESH:D003643', 'Disease') :: ['premature death'] @entity386 :: ('MESH:D001049', 'Disease') :: ['apnea']
@entity27 :: (MESH:D020181,Disease) :: ['obstructive sleep apnea']
