BACKGROUND: Renal allograft outcome, during an 8 year period (1985-1992), has been assessed in 56 renal transplants performed in 55 @entity1 who had @entity454 as a consequence of @entity5450 . The abnormalities were: primary @entity3025 ( @entity3025 ) or @entity8 (26 @entity1 ); @entity340 ( @entity340 ) (15); @entity1973 (6); vesico-ureteric @entity378 (5); @entity1494 (3); and @entity15342 (1). Six @entity1 had @entity1494 , and eight transplants were performed in seven @entity1 with urinary diversions. RESULTS: Overall, 1 and 5 year actuarial graft survival was 89 and 66%, with mean @entity1011 of 154 micromol/l +/- 11 (SE) and 145 +/- 9 respectively. @entity1 with abnormal bladders or conduits (n = 28) had worse graft function than those with normal bladders (n = 28) although graft survival was not significantly different in the two groups at 1 and 5 years: 93 and 75% with normal bladders vs 86 and 57% with abnormal systems. Symptomatic @entity293 were common in the first 3 months after transplantation (63%); fever and systemic symptoms occurred in 39% with normal bladders and 59% with abnormal bladders. @entity293 directly contributed to graft loss in six @entity1 with abnormal bladders, but had no consequences in those with normal bladders. CONCLUSIONS: Abnormal bladders must be assessed urodynamically before transplantation, and after transplantation adequacy of urinary drainage must be re-assessed frequently. Prophylactic antibiotics are now given for the first 6 months and @entity293 must be treated promptly. With these measures, good results, similar to those of @entity1 without urological problems, can be obtained.

Renal transplantation following renal failure due to XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal dysplasia'] @entity1494 :: ('MESH:D001745', 'Disease') :: ['augmented bladders', 'bladder exstrophy'] @entity5450 :: ('MESH:D014570', 'Disease') :: ['urological abnormalities'] @entity1973 :: ('MESH:D001750', 'Disease') :: ['neuropathic bladders'] @entity3025 :: ('MESH:D014718', 'Disease') :: ['vesicoureteric reflux', 'VUR'] @entity15342 :: ('MESH:D011535', 'Disease') :: ['prune belly syndrome'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity340 :: ('MESH:D006349', 'Disease') :: ['posterior urethral valves', 'PUV'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculosis'] @entity293 :: ('MESH:D014552', 'Disease') :: ['urinary tract infections', 'Urinary tract infection'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal failure']
@entity5450 :: (MESH:D014570,Disease) :: ['urological disorders']
