The most common sites of @entity1823 occurring in the head and neck region are the carotid body and vagal glomus. The clinical course of carotid body @entity1823 is characterized by two modes of development: locoregional growth and distant metastatic dissemination. Few cases of @entity5 have been reported in the literature. We report a case managed in the ENT Department of Grenoble university hospital in 1993. A 53-year-old @entity1 presented a bilateral functional ( @entity935 secretion) carotid @entity5 , stage II on the right side and stage I on the left side according to the Shamblin classification. Two successive excisions with complete resection were performed without complication. Two years after the second surgical excision, bone and liver @entity3 were diagnosed and visualized with a Ostreoscan scintigraphy. Clinical course was rapidly unfavorable and the @entity1 died a few weeks later. Malignant forms of @entity10470 are very uncommon and there is no cellular or histological appearance significantly contributing to the diagnosis of @entity5 . Clinical findings are the most reliable criteria for @entity5 , with the development of distant @entity3 usually after about 9 years. Long follow-up is essential. Histology in needed to establish the diagnosis of @entity3 . A histology specimen may not be possible for a functional @entity1823 . In this case scintigraphy can provide the diagnosis. Malignant forms are more frequent in case of functional @entity1823 , more particularly in case of @entity935 secretion.

[Malignant XXXX . A case report].

@entity1 :: ('9606', 'Species') :: ['woman', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant carotid body paraganglioma', 'tumor', 'malignancy'] @entity935 :: ('MESH:D004298', 'Chemical') :: ['dopamine'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity1823 :: ('MESH:D010235', 'Disease') :: ['paragangliomas', 'paraganglioma'] @entity10470 :: ('MESH:D002345', 'Disease') :: ['carotid paraganglioma']
@entity10470 :: (MESH:D002345,Disease) :: ['carotid paraganglioma']
