OBJECTIVE: To examine the prenatal course and outcomes of neonates with isolated @entity2241 . METHODS: A retrospective analysis (from 1990 through 2000) was performed on 26 consecutive cases presenting with @entity2241 . A systematic diagnostic protocol which included fetal blood sampling for karyotyping, serology and serial ultrasound examinations to determine etiology was followed in all cases after diagnosis. Pregnancy outcome was assessed by a chart report or autopsy reports. RESULTS: The majority of cases were associated with fetal @entity600 (n = 11). Five fetuses had @entity600 with associated syndromes. Less commonly associated were intrauterine @entity281 (n = 3), intestinal perforation (n = 2), @entity74 (n = 2), @entity5 (n = 1) and @entity851 (n = 1). In only 1 case (4%) was the etiology idiopathic. Secondary generalized @entity4 occurred only in 4 of 26 cases. Only 13 of 16 liveborn @entity1 survived past the neonatal period and only 4 cases are doing well at childhood age without any sequelae. CONCLUSION: A wide range of etiologies were associated with isolated @entity2241 . Those with @entity600 had the worst pregnancy outcome. Prenatal diagnosis was made in 92% utilizing a systematic diagnostic workup. The diagnosis of idiopathic @entity843 has become rare due to the improvement in prenatal diagnosis.

Etiology and prognosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['infants'] @entity851 :: ('MESH:D006130', 'Disease') :: ['growth retardation'] @entity5 :: ('MESH:D009369', 'Disease') :: ['neoplasm'] @entity4 :: ('MESH:D004487', 'Disease') :: ['hydrops'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity74 :: ('MESH:D030342', 'Disease') :: ['genetic disorders'] @entity2241 :: ('MESH:D005315', 'Disease') :: ['fetal ascites']
@entity2241 :: (MESH:D005315,Disease) :: ['fetal ascites']
