BACKGROUND/AIMS: The Mycotic Ulcer Treatment Trial I (MUTT I) was a double-masked, multicentre, randomised controlled trial, which found that topical @entity5896 is superior to @entity5074 for the treatment of @entity3283 . In this study, we determine risk factors for @entity4064 -related quality of life in @entity1 with @entity364 . METHODS: The Indian visual function questionnaire (IND-VFQ) was administered to MUTT I study @entity1 at 3   months. Associations between @entity1 and ulcer characteristics and IND-VFQ subscale score were assessed using generalised estimating equations. RESULTS: 323 @entity1 were enrolled in the trial, and 292 (90.4%) completed the IND-VFQ at 3   months. Out of a total possible score of 100, the average VFQ score for all @entity1 was 81.3 (range 0-100, SD 23.6). After correcting for treatment arm, each logMAR line of worse baseline visual acuity in the affected eye resulted in an average 1.2 points decrease on VFQ at 3   months (95% CI -1.8 to 0.6, p<0.001). Those who required therapeutic penetrating keratoplasty had an average of 25.2 points decrease on VFQ after correcting for treatment arm (95% CI -31.8 to -18.5, p<0.001). Study @entity1 who were unemployed had on average 28.5 points decrease on VFQ (95% CI -46.9 to -10.2, p=0.002) after correcting for treatment arm. CONCLUSIONS: Monocular vision loss from @entity5575 due to @entity364 reduced vision-related quality of life. Given the relatively high worldwide burden of @entity5575 , improving treatment outcomes of @entity281 should be a public health priority. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov Identifier: NCT00996736.

Risk factors for XXXX related functioning in the Mycotic Ulcer Treatment Trial: a randomised trial comparing @entity5896 with @entity5074 .

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'patient'] @entity5575 :: ('MESH:D003318', 'Disease') :: ['corneal opacity'] @entity281 :: ('MESH:D007239', 'Disease') :: ['corneal infections'] @entity364 :: ('MESH:D009181', 'Disease') :: ['fungal keratitis'] @entity3283 :: ('MESH:D003320', 'Disease') :: ['filamentous fungal corneal ulcers'] @entity5074 :: ('MESH:C102790', 'Chemical') :: ['voriconazole'] @entity5896 :: ('MESH:D010866', 'Chemical') :: ['natamycin'] @entity4064 :: ('MESH:D015354', 'Disease') :: ['low vision']
@entity4064 :: (MESH:D015354,Disease) :: ['low vision']
