INTRODUCTION: @entity13876 is a @entity1372 channel blocker antiepileptic drug authorized as an adjunctive therapy for focal @entity410 in adolescents and adults. AIM: To analyze the efficacy and safety of @entity13876 in Galicia according to its use in daily clinical practice. @entity1 AND METHODS: Retrospective observational study in @entity1 who started treatment with @entity13876 between January 2014 and June 2013 in 10 hospitals in Galicia, Spain. Its efficacy and safety at 3, 6 and 12 months after starting @entity13876 was assessed. RESULTS: We included 184 @entity1 with a mean age of 44.2    17.4 years old; 56.5% (n = 104) were male; 173 @entity1 constituted the efficacy population. Mean duration of @entity302 was 18.8    15.5 years. @entity410 frequency was 2.5    1.6 episodes/month. After 12 months, 68.2% of @entity1 (n = 118) had >= 50% improvement (responders) and among them, 54 (45.8% of responder @entity1 ) were @entity410 free. Twenty-three percent (n = 43) suffered from adverse events after 12 months, being dizziness (10.3%) and instability (3.3%) the most frequently reported. After the 12 month visit, 87.5% of @entity1 (n = 161) continued treatment with @entity13876 . CONCLUSIONS: @entity13876 provides a very good efficacy and safety profile for @entity1 with focal @entity302 . High percentage of responders may be related to a less refractory population compared to other daily clinical practice studies. It constitutes an attractive therapeutic option for the treatment of @entity1625 .

[Clinical experience with XXXX in Galicia: the GALACO study].

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures', 'Seizure'] @entity1625 :: ('MESH:D004828', 'Disease') :: ['focal epilepsies'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity13876 :: ('MESH:C403507', 'Chemical') :: ['lacosamide', 'Lacosamide'] @entity302 :: ('MESH:D004827', 'Disease') :: ['refractory epilepsy', 'epilepsy']
@entity13876 :: (MESH:C403507,Chemical) :: ['lacosamide']
