BACKGROUND: Blood pressure (BP) variability is associated with target organ damage in @entity101 and @entity6 . The 24 h ambulatory blood pressure monitoring (24 h-ABPM) has been proposed as an evaluation for BP variability using several indexes [standard deviation (SD) of mean BP, coefficient of variation (CV), BP variation over time (time-rate index)]. METHODS: We evaluated the association between BP variability measured by 24 h-ABPM indexes and echocardiographic variables in a cross-sectional study in 305 @entity101 @entity1 . RESULTS: Two groups were defined by the median (0.55 mmHg/min) of time-rate systolic BP (SBP) index and classified as low or high variability. Age was 57.3    6.2 years, 196 (64.3%) were female. @entity6 duration was 10.0 (5.0-16.2) years, HbA1c was 8.2    1.9%. Baseline clinical characteristics were similar between low (n = 148) and high (n = 157) variability groups. Office SBP and systolic 24 h-ABPM were higher in the high variability group (139.9 mmHg vs 146.0 mmHg, P = 0.006; 128.3 mmHg vs 132.9 mmHg, P = 0.019, respectively). Time-rate index, SD and CV of SBP, were higher in high variability group (P < 0.001; P < 0.001 and P = 0.003, respectively). Time-rate index was not independently associated with the echocardiography's variables in multiple linear model when adjusting for age, 24 h-ABPM, @entity6 duration and HbA1c. The multiple linear regression model revealed that the significant and independent determinants for septum thickness, relative wall thickness and posterior wall thickness (parameters of @entity4346 ) were: age (p = 0.025; p = 0.010; p = 0.032, respectively) and 24 h-SBP (p < 0.001 in the three parameters). CONCLUSION: BP variability estimated by 24 h-ABPM is not independently associated with echocardiographic parameters in @entity101 @entity1 .

Blood pressure variability and its association with echocardiographic parameters in hypertensive @entity6 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['left ventricular hypertrophy'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'diabetic-hypertensive'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetes']
@entity1 :: (9606,Species) :: ['patients']
