OBJECTIVE: To observe the clinical and biological characteristics of Non-IgM-secreting @entity706 ( @entity706 ) and draw the differences between non-IgM @entity706 and @entity8057 ( @entity8057 ). METHODS: Records of 13 @entity1 with non-IgM @entity706 were retrospectively analyzed between January 2000 and December 2013. The cytogenetic aberrations were detected by fluorescence in situ hybridisation (FISH). RESULTS: In the cohort, 7 males and 6 females with a median age of 63 years (range 43 to 74), two @entity1 were IgA secreting, 6 with IgG secreting and 5 patients without monoclonal globulin. The major complaint at diagnosis included @entity417 associated symptom (53.8%), mucocutaneous @entity548 and superficial @entity3329 (15.4%). Eight @entity1 had B symptom at diagnosis. All of the 13 @entity1 had bone @entity236 and @entity417 , and 10 @entity1 had 2 or 3 lineage @entity1503 . In 5 @entity1 with available immunophenotypic data, all expressed @entity1075 , @entity2225 , @entity10317 and @entity7211 , but missed the expression of @entity2282 , @entity19002 and @entity3053 . Two cases had @entity5893 or sIgM positive alone. Another 2 @entity1 were @entity7527 or @entity2935 positive and 3 @entity1 were FMC7 positive. @entity2008 had been detected by FISH in 7 @entity1 , but only two (28.6%) @entity1 had aberrations with del(6q). CONCLUSION: The clinical and biological characteristics had no significantly difference between non-IgM @entity706 and @entity8057 .

[Clinical and biological characteristics of non-IgM XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['lymphadenopathy'] @entity19002 :: ('3682', 'Gene') :: ['CD103'] @entity2008 :: ('MESH:D002869', 'Disease') :: ['Cytogenetic aberrations'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anemia'] @entity706 :: ('MESH:D008223', 'Disease') :: ['LPL', 'lymphoplasmacytic lymphoma'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity1075 :: ('930', 'Gene') :: ['CD19'] @entity2225 :: ('54474', 'Gene') :: ['CD20'] @entity5893 :: ('921', 'Gene') :: ['CD5'] @entity2935 :: ('3687', 'Gene') :: ['CD11c'] @entity2282 :: ('4311', 'Gene') :: ['CD10'] @entity236 :: ('MESH:D001855', 'Disease') :: ['marrow involvement'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['cytopenia'] @entity3053 :: ('952', 'Gene') :: ['CD38'] @entity7211 :: ('3669', 'Gene') :: ['CD25'] @entity7527 :: ('2208', 'Gene') :: ['CD23'] @entity8057 :: ('MESH:D008258', 'Disease') :: ['Waldenstr  m macroglobulinemia', 'WM'] @entity10317 :: ('933', 'Gene') :: ['CD22']
@entity706 :: (MESH:D008223,Disease) :: ['lymphoplasmacytic lymphoma']
