Clinical studies have shown that probiotics positively affect oral health by decreasing gum bleeding and/or reducing salivary counts of certain oral pathogens. Our aim was to investigate the inhibitory effect of six probiotic lactobacilli against opportunistic @entity6923 species. Sugar utilisation by both lactobacilli and Candida was also assessed. Agar overlay assay was utilised to study growth inhibition of @entity5132 , @entity7408 and Candida krusei by @entity1905 , @entity3869 @entity6329 Shirota, @entity68352 , @entity3869 CD2, @entity6330 LB86 and @entity6330 LB Lact. The inhibitory effect was measured at pH 5.5, 6.4, and 7.2, respectively, and in the presence of five different @entity3363 in growth medium ( @entity413 , @entity948 , @entity1132 , @entity969 , and @entity5121 ). Growth and final pH values were measured at two-hour time points to 24 h. @entity1905 showed the strongest inhibitory activity in @entity948 and @entity413 medium against @entity5132 , followed by @entity6329 Shirota, @entity68352 and @entity3869 CD2. None of the lactobacilli tested affected the growth of C. krusei. Only @entity1905 produced slight inhibitory effect on @entity7408 . The lower pH values led to larger inhibition zones. Sugar fermentation profiles varied between the strains. @entity6329 Shirota grew in the presence of all @entity3363 tested, whereas @entity3869 CD2 could utilise only @entity413 and @entity948 . All Candida species metabolised the available @entity3363 but the most rapid growth was observed with @entity7408 . The results suggest that commercially available probiotics differ in their inhibitory activity and @entity1735 utilisation; the above properties are modified by different pH values and @entity3363 with more pronounced inhibition at lower pH.

Inhibitory activity in vitro of probiotic lactobacilli against XXXX under different fermentation conditions.

@entity6923 :: ('MESH:C536777', 'Disease') :: ['oral Candida'] @entity7408 :: ('5478', 'Species') :: ['C. glabrata', 'Candida glabrata'] @entity948 :: ('MESH:D005632', 'Chemical') :: ['fructose'] @entity5121 :: ('MESH:D013012', 'Chemical') :: ['sorbitol'] @entity6329 :: ('1582', 'Species') :: ['L. casei', 'casei'] @entity1132 :: ('MESH:D007785', 'Chemical') :: ['lactose'] @entity1735 :: ('CHEBI:16646', 'Chemical') :: ['carbohydrate'] @entity5132 :: ('5476', 'Species') :: ['C. albicans', 'Candida albicans'] @entity3869 :: ('1580', 'Species') :: ['Lactobacillus', 'L. brevis', 'Lactobacillus brevis'] @entity969 :: ('MESH:D013395', 'Chemical') :: ['sucrose'] @entity6330 :: ('1585', 'Species') :: ['Lactobacillus bulgaricus', 'L. bulgaricus'] @entity68352 :: ('491077', 'Species') :: ['L. reuteri SD2112', 'Lactobacillus reuteri SD2112'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity1905 :: ('568703', 'Species') :: ['L. rhamnosus GG', 'Lactobacillus rhamnosus GG'] @entity3363 :: ('MESH:D002241', 'Chemical') :: ['carbohydrates', 'sugars']
@entity6923 :: (MESH:C536777,Disease) :: ['oral Candida']
