OBJECTIVES: Diverting ileostomy is used as a temporizing therapy in @entity1 with @entity30 ; however, little data exist regarding its use for @entity1049 . The primary aim of the present study was to determine the role of diversion in severe @entity29 ( @entity29 ) in a pediatric population. METHODS: Retrospective study of @entity1 who underwent diverting ileostomy at The @entity1 's Hospital of Philadelphia from 2000 to 2014 for the management of severe, refractory colonic @entity29 . Clinical variables were compared in the 1 year before ileostomy and 1 year after diversion. Surgical and disease outcomes including changes in diagnosis were reviewed through 2015. RESULTS: Twenty-four @entity1 underwent diverting ileostomy for refractory @entity1049 . Initial diagnoses were @entity30 in 10 (42%), @entity31 in 1 (4%), and @entity29 -unclassified in 13 @entity1 (54%). Comparing data before and after surgery, there were statistically significant improvements in height and weight velocities, height velocity z score, blood transfusion requirement, hemoglobin, and hospitalization rates. Chronic @entity479 use decreased from 71% to 22%. At the conclusion of the study, 10 @entity1 had undergone subsequent colectomy, 7 had successful bowel reanastomosis, and 7 remain diverted. Seven @entity1 (29%) had a change in diagnosis. There were 13 surgical complications in 7 subjects, including prolapse reduction, stoma revision, and resection of @entity63 bowel. CONCLUSIONS: In pediatric @entity1 with refractory colonic @entity29 , diverting ileostomy can be a successful intervention to induce clinical stability. Importantly, diversion is a @entity479 -sparing therapy and allows additional time to clarify the diagnosis.

Diverting Ileostomy for the Treatment of Severe, Refractory, Pediatric XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Children'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis'] @entity29 :: ('MESH:D015212', 'Disease') :: ['refractory colonic inflammatory bowel disease', 'IBD'] @entity30 :: ('MESH:D003424', 'Disease') :: ['Crohn disease', 'perianal Crohn disease'] @entity1049 :: ('MESH:D003108', 'Disease') :: ['colonic disease'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity29 :: (MESH:D015212,Disease) :: ['Inflammatory Bowel Disease']
