BACKGROUND: There is very limited information on the association between @entity50469 and serum uric acid levels or @entity210 . The aim of this study was to investigate the association of @entity50469 with @entity5052 and @entity210 in US adults. METHODS: A cross-sectional study was conducted in 5632 adults aged 20years or older from the National Health and Nutrition Examination Survey (NHANES) 2003-2010 with determinations of serum uric acid and urine total @entity50469 and dimethylarsinate (DMA). @entity5052 was defined as serum uric acid higher than 7.0mg/dL for @entity1 and 6.0mg/dL for @entity1 . Gout was defined based on self-reported physician diagnosis and medication use. RESULTS: After adjustment for sociodemographic factors, comorbidities and arsenobetaine levels, the increase in the geometric means of serum uric acid associated with one interquartile range increase in total @entity50469 and DMA levels was 3% (95% CI 2-5) and 3% (2-5), respectively, in @entity1 and 1% (0-3) and 2% (0-4), respectively, in @entity1 . In @entity1 , the adjusted odds ratio for @entity5052 comparing the highest to lowest quartiles of total @entity50469 was 1.84 (95% CI, 1.26-2.68) and for DMA it was 1.41 (95% CI, 1.01-1.96). The corresponding odds ratios in @entity1 were 1.26 (0.77, 2.07) and 1.49 (0.96, 2.31), respectively. The odds ratio for @entity210 comparing the highest to lowest tertiles was 5.46 (95% CI, 1.70-17.6) for total @entity50469 and 1.98 (0.64-6.15) for DMA among @entity1 older than 40years old. Urine @entity50469 was not associated with @entity210 in @entity1 . CONCLUSION: Low level @entity50469 exposures may be associated with the risk of @entity5052 in @entity1 and with the prevalence of @entity210 in @entity1 . Prospective research focusing on establishing the direction of the relationship among @entity50469 , @entity5052 , and @entity210 is needed.

Arsenic exposure, @entity5052 , and XXXX in US adults.

@entity5052 :: ('MESH:D033461', 'Disease') :: ['hyperuricemia', 'Hyperuricemia'] @entity210 :: ('MESH:D006073', 'Disease') :: ['gout'] @entity1 :: ('9606', 'Species') :: ['women', 'men'] @entity50469 :: ('MESH:D020261', 'Disease') :: ['arsenic']
@entity210 :: (MESH:D006073,Disease) :: ['gout']
