BACKGROUND: Currently there are few reports comparing gastrointestinal (GI) symptoms in the morbidly @entity28 versus control subjects or the effect of laparoscopic Roux-en-Y gastric bypass (LRYGBP) on such symptoms. METHODS: A previously validated, 19-point GI symptom questionnaire was administered prospectively to each @entity1 undergoing LRYGBP, and the questionnaire was re-administered 6 months postoperatively. Six symptom clusters ( @entity490 , @entity146 bowel [ @entity5377 ], reflux, @entity354 [ @entity354 ], @entity25 , and @entity1282 ) were compared in the following manner using Students t-test: 1) Control vs. Preop, 2) Control vs Postop, and 3) Preop vs Postop. Results are expressed as mean +/- standard deviation, significance P=0.05. RESULTS: 43 @entity1 (40 female and 3 male, age 37.3 +/- 8.6, BMI 47.8 +/- 4.9) completed the questionnaire preoperatively, and 36 @entity1 (34 female, 2 male, BMI 31.6 +/- 5.3) completed the questionnaire 6 months postoperatively, for a response-rate of 84%. @entity490 , @entity5377 , reflux, @entity354 and @entity25 were significantly worse in preop versus controls. @entity1282 was not different. Postop vs preop scores revealed @entity490 , @entity5377 , @entity354 , reflux, and @entity25 to be improved significantly. @entity1282 was not significantly different. Only @entity1282 was worse when comparing postoperative to controls. No other symptom cluster was significantly different in controls vs postoperative. CONCLUSIONS: Morbidly @entity28 @entity1 experience more intense GI symptoms than control subjects, and many of these symptoms return to control levels 6 months after LRYGBP. @entity1282 is equivalent to control subjects preoperatively but increases significantly after LRYGBP. This data suggests another quality-of-life improvement (relief of GI symptoms) for morbidly @entity28 @entity1 . Further follow-up is needed to document the long-term reduction of GI symptoms.

Gastrointestinal symptoms are more intense in morbidly XXXX @entity1 and are improved with laparoscopic Roux-en-Y gastric bypass.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5377 :: ('MESH:D053560', 'Disease') :: ['IBS'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity146 :: ('MESH:D001523', 'Disease') :: ['irritable'] @entity490 :: ('MESH:D015746', 'Disease') :: ['Abdominal pain', 'abdominal pain'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux disease', 'GERD'] @entity1282 :: ('MESH:D003680', 'Disease') :: ['Dysphagia', 'dysphagia'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep disturbance symptoms', 'sleep disturbances']
@entity28 :: (MESH:D009765,Disease) :: ['obese']
