OBJECTIVE: Initial presentation with primary spinal involvement in @entity6275 ( @entity6275 ) is rare. Our objective was to review the imaging appearances of three @entity1 who had @entity6275 who initially presented with isolated primary spinal involvement. DESIGN AND @entity1 : The imaging, clinical, laboratory and histology findings of the three @entity1 were retrospectively reviewed. Imaging included seven spinal MR imaging scans, one computed tomography scan, nine bone scans, two tomograms and 16 radiographs. These were reviewed by two musculoskeletal radiologists and a consensus view is reported. All three @entity1 presented with atraumatic @entity158 and had extensive bone spinal pathology. The @entity1 were aged 11, 13 and 12 years. There were two females and one male. RESULTS AND CONCLUSIONS: The initial @entity1 had thoracic T6 and T8 vertebra plana. Bone scan showed additional vertebral body involvement. Follow-up was available over a 3 year period. The second @entity1 had partial collapse of T9 and, 2 years later, of C6. Subsequently extensive @entity66 ensued and follow-up was available over 8 years. The third @entity1 initially had L3 inferior partial collapse and 1 year later T8 involvement with @entity66 . Follow-up was available over 3 years. The imaging findings of the three @entity1 include @entity2444 with a subchondral line adjacent to endplates associated with bone marrow MR signal alterations. Awareness of the imaging appearances may help the radiologist to include this entity in the differential diagnosis in @entity1 who present with spinal pathology and no history of @entity130 . Histopathological examination excludes @entity5 and @entity281 but with typical imaging findings may not always be necessary.

Imaging of XXXX first presenting with isolated primary spinal involvement.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient', 'PATIENTS'] @entity6275 :: ('MESH:C535456', 'Disease') :: ['chronic recurrent multifocal osteomyelitis of childhood', 'CRMO'] @entity66 :: ('MESH:D004194', 'Disease') :: ['multifocal disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity158 :: ('MESH:D010146', 'Disease') :: ['spinal pain'] @entity2444 :: ('MESH:D007873', 'Disease') :: ['partial and complete vertebra plana'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity6275 :: (MESH:C535456,Disease) :: ['chronic recurrent multifocal osteomyelitis of childhood']
