PURPOSE: To determine the value of visual evoked potentials with blue-on-yellow pattern stimulation in follow-up of @entity726 . METHODS: This prospective longitudinal concurrent study included a heterogeneous cohort of two groups, perimetric (n = 161) and preperimetric (n = 118), of @entity1 with chronic @entity1538 and 113 healthy control subjects. In the preperimetric @entity726 group, @entity1 showed @entity854 of the optic disc, maximum intraocular pressure higher than 21 mm Hg, and unremarkable computerized visual field examination results. @entity1 underwent up to three VEP measurements with blue-on-yellow pattern stimulation, as well as qualitative and morphometric evaluation of color stereo optic disc photographs. Mean follow-up time between measurements was 24 months. VEP measurements were separately analyzed in preperimetric subjects, with and without progression of @entity1781 . Progression of @entity726 was defined as increasing loss of neuroretinal rim. RESULTS: A separate analysis of VEP peak times in @entity1 in the preperimetric group, with and without progression of glaucomatous @entity1781 , showed no significant difference at baseline but a significant prolongation (P = 0.01) in @entity1 with progressive disease, 2 years before morphologic changes were evident. VEPs in @entity1 with nonprogressive disease were statistically unchanged during the observation period. The perimetric group and both preperimetric groups showed significantly prolonged VEP peak times in comparison with the control group (P < 0.001). CONCLUSIONS: In addition to photographic evaluation to detect glaucomatous disc @entity194 , the blue-on-yellow VEP may be an objective electrophysiological tool for monitoring @entity1 with @entity726 , because peak times are significantly associated with progression of @entity1781 .

Monitoring XXXX progression with visual evoked potentials of the blue-sensitive pathway.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open-angle glaucoma'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity854 :: ('MESH:D018376', 'Disease') :: ['glaucomatous abnormalities'] @entity1781 :: ('MESH:D009901', 'Disease') :: ['optic nerve damage'] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy']
@entity726 :: (MESH:D005901,Disease) :: ['glaucoma']
