INTRODUCTION: Primary @entity320 is a rare @entity5 representing only 0.1-0.2% of @entity5 . The goal of the study was to report on the management of a new case diagnosed and treated in our site. CASE REPORT: A 67-year-old @entity1 presented with @entity1282 to solids with no other remarkable history or associated @entity272 . He underwent gastroscopy, which revealed a polypoid mass suggestive of @entity5 in the distal third of the esophagus. Biopsy indicated @entity320 with positive immunohistochemical markers S100 and HMB45, and negative cytokeratins and CEA. Computerized tomography (CT) and positron-emission tomography (PET) scans showed no local infiltration or distant metastases. An Ivor-Lewis esophagectomy procedure was performed with regional lymphadenectomy. Postoperative stay lasted for three weeks, and no remarkable postsurgical complications arose. The pathological study of the specimen confirmed the diagnosis of primary @entity320 . DISCUSSION: Primary @entity320 has an unfortunate prognosis as it is an aggressive @entity5 usually diagnosed at an advanced stage, with local invasion and @entity3 . Currently, surgery is the treatment of choice, with the remaining adjuvant therapies obtaining limited results.

Primary XXXX : report of a case.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'neoplasm', 'esophageal malignancies'] @entity1282 :: ('MESH:D003680', 'Disease') :: ['dysphagia'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesions'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic disease'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma', 'esophageal melanoma', 'malignant melanoma of the esophagus']
@entity320 :: (MESH:D008545,Disease) :: ['esophageal melanoma']
