BACKGROUND: Severe @entity508 may lead to problems of movement and function, @entity158 and hygiene, and may be difficult to treat. A team of neurologists and physiotherapists evaluated the effect of botulinum toxin A (BTX-A) on @entity508 . MATERIAL AND METHODS: Ten @entity1 with @entity6220 were included in this study. Function, @entity158 and personal hygiene were assessed before and after injections with BTX-A. RESULTS: Nine @entity1 experienced improvement of function and/or @entity158 relief. One @entity1 had improved perception in his hand, and one @entity1 needed only two injections to stop a vicious circle. The effect varied from @entity1 to @entity1 . It seemed that @entity1 with some preserved motor control in the spastic limb could use it to learn more appropriate movement strategies. INTERPRETATION: We recommend that doctors and physiotherapists work together to identify muscle groups that need to be targeted for injection and evaluate consequences of the treatment. Injections with BTX-A should be combined with physiotherapy.

[Botulinum toxin A--effect on XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity508 :: ('MESH:D009128', 'Disease') :: ['spasticity'] @entity6220 :: ('MESH:D020279', 'Disease') :: ['central nervous disorders'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity508 :: (MESH:D009128,Disease) :: ['spasticity']
