BACKGROUND: @entity5 are the second leading cause of @entity204 , despite the huge progress in medical sciences in the last 20 years. Recently, @entity356 morbidity has decreased, but mortality is still at a high level. MATERIAL/METHODS: Tissues from 24 @entity1 with a histopathologically diagnosed @entity356 were tested. @entity1 were divided into 2 equal groups: @entity1 without @entity3 (G1) and @entity1 with @entity3 in the liver (G2). In all tested tissues of @entity2818 , the expression of @entity7 ( @entity7 ) and metalloproteinase 2, respectively, were estimated. RESULTS: Results revealed a statistically significant increase in the @entity7 expression for @entity2818 in relation to the margin (p1<0.001; p2<0.001). The increase of gene expression for @entity7 did not significantly differ statistically in @entity2818 . The obtained results revealed a statistically significant difference in the increase of gene expression for @entity1476 in G1 in relation to the margin (p<0.05) and a very high one in G2 in relation to the average margin value (p<0.001). A highly statistically significant correlation was obtained for @entity7 and @entity1476 in the tissue of @entity1 with @entity3 (p<0.001; r=0.714). The highly elevated expression of @entity1476 in the tissue of @entity356 in @entity1 with @entity3 confirms its participation in the invasiveness of the neoplasmatic process. CONCLUSIONS: The highly significant correlation between @entity7 and @entity1476 suggests a connection between both mechanisms in the progression of @entity356 .

@entity7 ( XXXX ) expression in @entity356 tissue.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2818 :: ('5544;200575', 'Gene') :: ['G1 and G2'] @entity7 :: ('7422', 'Gene') :: ['vascular endothelial growth factor', 'VEGF'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Neoplasms'] @entity1476 :: ('4313', 'Gene') :: ['MMP-2'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death in Poland after vessel diseases'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'mucosal and adenomucosal gastric cancer']
@entity1476 :: (4313,Gene) :: ['MMP 2']
