BACKGROUND/AIMS: @entity3178 ( @entity3178 ) encompasses collagenous and @entity11162 and is characterized by chronic @entity294 . In cases of @entity3178 , colonic mucosae are macroscopically normal, and diagnostic histopathological features are observed only upon microscopic examination. We designed a prospective multicenter study to determine the clinical features, pathological distribution in the colon and prevalence of @entity3178 in Korea. METHODS: We prospectively enrolled @entity1 having watery @entity294 no more than 3 times a day between March 2008 and February 2009. We obtained @entity1 histories and performed colonoscopies with random biopsies at each colon segment. RESULTS: A total of 100 @entity1 with chronic @entity294 were enrolled for a normal colonoscopy and stool exam. @entity3178 was observed in 22 @entity1 (22%) (M:F 1.2:1; mean age, 47.5 years). Of those 22 @entity1 , 18 had @entity11162 and 4 had @entity4143 . The entire colon was affected in only 3 cases (13.6%), the ascending colon in 6 cases (27.2%), the transverse colon in 3 cases (13.6%), and the left colon in 3 cases (13.6%). More than 2 segments were affected in 7 cases (31.8%). Nonsteroidal anti-inflammatory drug-associated MCs were observed in 4 cases (18.2%), 3 of which showed improved @entity294 symptoms following discontinuation of the medication. Frequently associated symptoms were @entity490 and @entity353 . @entity792 were observed in 4 cases (18.2%). Half of the 22 @entity1 with @entity3178 improved with conservative care by @entity3062 or probiotics. CONCLUSIONS: In a prospective multicenter study of Korean @entity1 with chronic @entity294 , the frequency of @entity3178 was found to be approximately 20%, similar to the percentage observed in Western countries. Therefore, the identification of @entity3178 is important for the adequate management of Korean @entity1 with chronic @entity294 .

Clinical Characteristics of XXXX in Korea: Prospective Multicenter Study by KASID.

@entity11162 :: ('MESH:D046730', 'Disease') :: ['lymphocytic colitis'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity3178 :: ('MESH:D046728', 'Disease') :: ['Microscopic colitis', 'MC'] @entity792 :: ('MESH:D001327', 'Disease') :: ['Autoimmune diseases'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity4143 :: ('MESH:D046729', 'Disease') :: ['collagenous colitis'] @entity3062 :: ('MESH:D008139', 'Chemical') :: ['loperamide']
@entity3178 :: (MESH:D046728,Disease) :: ['Microscopic Colitis']
