The objective of this paper was to investigate the incidence of extra-intestinal infections caused by @entity2718 . During a 10-year period, the microbiology laboratory of our institution isolated 2034 isolates of @entity2718 . Of the 2034 isolates, 21 (1.08%) were obtained from extra-intestinal sources. This represents an incidence of extra-intestinal isolation of four cases per 100 000 admissions. We were able to review the records of 17 @entity1 for our study. The isolates in 12 @entity1 were obtained from structures or fluids anatomically close to the colon and included the following infections: @entity298 in five cases (three primary and two secondary), @entity6177 in three @entity1 and @entity2737 in four cases. The infections in the other five @entity1 were not in the anatomic vicinity of the colon. They included one case with a @entity867 , two episodes of @entity2259 and two cases of @entity281 (one @entity6275 ). In all but one case, @entity2718 isolation was obtained as part of a polymicrobial flora. The isolates were frequently non-toxigenic and the extra-intestinal infections occurred without concomitant @entity294 or prior anti-microbial therapy. Out of the 17 @entity1 , eight died and nine survived. Death could not be directly attributed to @entity2718 in any of the cases. The isolation of @entity2718 outside the intestinal tract is very uncommon. Its clinical significance should be interpreted with caution.

Extra-intestinal infections caused by XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6275 :: ('MESH:C535456', 'Disease') :: ['chronic osteomyelitis'] @entity6177 :: ('MESH:D018784', 'Disease') :: ['intra-abdominal abscesses'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity2737 :: ('MESH:D014946', 'Disease') :: ['abdominal wound infections'] @entity281 :: ('MESH:D007239', 'Disease') :: ['foot infections'] @entity867 :: ('MESH:D001922', 'Disease') :: ['brain abscess'] @entity2718 :: ('1496', 'Species') :: ['C. difficile', 'Clostridium difficile'] @entity2259 :: ('MESH:D016470', 'Disease') :: ['bacteremia'] @entity298 :: ('MESH:D010538', 'Disease') :: ['peritonitis']
@entity2718 :: (1496,Species) :: ['Clostridium difficile']
