In order to observe the expression of Fas, @entity12 and @entity588 and apoptosis of bone marrow @entity2280 (+) cells in @entity1 with @entity2590 ( @entity2590 ), and to explore the relation between the expression of these antigens and apoptosis, the expression of Fas, @entity12 and @entity588 and apoptosis of bone marrow @entity2280 (+) cell were evaluated by flow cytometry in 26 @entity1 with @entity2590 including 9 cases of @entity417 ( @entity417 ), 1 case of @entity417 with ringed sideroblasts (RAS), 9 cases of @entity417 ( @entity417 ) and 7 cases of @entity417 ( @entity417 ), 10 @entity1 with @entity3052 ( @entity3052 ) and 6 control @entity1 with normal bone marrow. The results showed that the expression of Fas and @entity12 of @entity2280 (+) cells significantly increased in all types of @entity2590 @entity1 compared with control group (P < 0.01). The expression of @entity588 on @entity2280 (+) cells in @entity417 and @entity417 @entity1 was much higher as compared with that in control group (P < 0.01), but there was no significant difference between @entity417 /RAS @entity1 and control group (P > 0.05). The expression rates of Fas on @entity2280 (+) cells were almost identical in all kinds of @entity2590 , but there was significant difference on the expression of @entity588 ( @entity417 /RAS < @entity417 < @entity417 ). Apoptosis of @entity2280 (+) cells significantly increased in @entity417 /RAS and @entity417 @entity1 compared with control group (P < 0.01), but there was no difference between @entity417 and control group. Moreover, apoptosis of @entity2280 (+) cells in control much higher than that in @entity3052 group (P < 0.01). There was no correlation between the expression of Fas or @entity12 and apoptosis on @entity2280 (+) cell of @entity2590 @entity1 . Nevertheless, there was a negative correlation between the expression of @entity588 and apoptosis. It is concluded that apoptosis of @entity2280 (+) cells was affected by a lot of factors in @entity2590 , in which @entity588 is an important factor of depressing apoptosis. During the progress from @entity2590 to @entity3052 , apoptosis changes from overgoing to deficiency in @entity2280 (+) cell.

[Expression of Fas, @entity12 and @entity588 and apoptosis of bone marrow XXXX + cells in @entity1 with @entity2590 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity588 :: ('596', 'Gene') :: ['Bcl-2'] @entity417 :: ('MESH:D000740', 'Disease') :: ['refactory anemia', 'RAEB-t', 'RA with excess blasts', 'RAEB in transformation', 'RAEB', 'RA'] @entity2590 :: ('MESH:D009190', 'Disease') :: ['myelodysplastic syndrome', 'MDS'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['acute myeloid leukemia', 'AML'] @entity12 :: ('356', 'Gene') :: ['FasL'] @entity2280 :: ('947', 'Gene') :: ['CD34']
@entity2280 :: (947,Gene) :: ['CD34']
