OBJECTIVE: Endoscopic sphincterotomy (ES) reduces sphincter function, which may allow reflux of pancreatic juice and intestinal contents into the common bile duct. The reflux, if present, may cause development of @entity1125 , as may @entity3161 . We prospectively investigated pancreatobiliary and duodenobiliary reflux after ES. METHODS: In 15 @entity1 with @entity2877 , ductal bile was sampled for amylase concentration and bacterial culture during endoscopic retrograde cholangiopancreatography, before and at 7 days to 5 yr after ES. To provide comparative data, ductal bile was sampled in 11 @entity1 with gallbladder @entity165 polyps or @entity3161 who did not undergo ES. RESULTS: Amylase concentration of ductal bile in @entity1 with @entity2877 before ES was not different from that in @entity1 with @entity1127 . Its concentration was increased 7 days after ES compared with that before ES, reaching the level of that in @entity1 with @entity3161 . Thereafter, amylase concentration gradually decreased, returning to that before ES by 1 yr. After ES, bactobilia occurred in 60-80% of @entity1 , although none developed acute @entity255 . CONCLUSIONS: Although ES causes transient @entity354 is abolished by 1 yr after ES. ES is unlikely to increase the risk for development of biliary tract @entity189 as long as @entity255 or bile duct stones do not recur.

Does endoscopic sphincterotomy cause prolonged XXXX ?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['gallbladder polyps'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity255 :: ('MESH:D002761', 'Disease') :: ['cholangitis'] @entity3161 :: ('MESH:D020511', 'Disease') :: ['anomalous pancreaticobiliary junction'] @entity354 :: ('MESH:D005764', 'Disease') :: ['pancreatobiliary reflux, the reflux'] @entity2877 :: ('MESH:D042883', 'Disease') :: ['choledocholithiasis'] @entity1125 :: ('MESH:D001661', 'Disease') :: ['biliary tract carcinomas'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity354 :: (MESH:D005764,Disease) :: ['pancreatobiliary reflux']
