BACKGROUND: Decompressive craniectomy (DC) with duroplasty is the gold standard for @entity428 despite paucity of randomized controlled trials. There are several morbidities associated with DC of which the persistence of @entity154 is of paramount importance. Studies have shown that many of the morbidities associated with DC get reversed following replacement of the bone flap. AIM: To design a novel technique for control of refractory intracranial pressure (ICP), as well as to study its safety and efficacy compared to the conventional DC technique. MATERIAL AND METHODS: We conducted a prospective, comparative, observational pilot study comparing four-quadrant @entity5663 (FoQOsD) with conventional DC. The demographic features, postoperative variables such as operating time, number of days of intensive care unit (ICU) stay and survival, as well as radiographic variables such as change in the @entity601 ( @entity601 ) and expansion of the compressed brain were analyzed using relevant statistical tests. RESULTS: Twenty @entity1 were selected and grouped into two groups of 10 @entity1 each. The male: female ratio in the two groups were 8:2 and 7:3, respectively, and the mean age at presentation was 42.7    1.45 years in the FoQOsD group and 43.6    1.32 years in the DC group. Both the groups were comparable in relation to the duration of surgery, duration of ICU stay, and survival (P > 0.05). There was significant brain expansion and reversal of @entity601 (P < 0.001) in the FoQOsD group, factors which were comparable to that in the DC group. CONCLUSIONS: FoQOsD may be as effective as conventional DC in managing @entity428 . This procedure mainly avoids a revision cranioplasty. A prospective randomized controlled trial with a large sample size may be initiated for obtaining more accurate data.

Four-quadrant XXXX : A novel technique for @entity428 - A pilot study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity154 :: ('MESH:D000013', 'Disease') :: ['bony defect'] @entity428 :: ('MESH:D019586', 'Disease') :: ['refractory intracranial hypertension', 'intracranial hypertension'] @entity5663 :: ('MESH:D003665', 'Disease') :: ['osteoplastic decompressive craniotomy'] @entity601 :: ('MESH:D009436', 'Disease') :: ['midline shift', 'MLS']
@entity5663 :: (MESH:D003665,Disease) :: ['osteoplastic decompressive craniotomy']
