OBJECTIVES: To determine, in preschool @entity1 with an @entity697 , the responsiveness to change of respiratory resistance measurements obtained by the forced oscillation (Rfo) technique, and to identify the magnitude of change indicative of @entity1224 reversibility. DESIGN/SETTING: A prospective observational study of 114 @entity1 , aged 3 to 17 years, untrained in the Rfo technique and treated for acute @entity565 in a tertiary-care pediatric @entity341 ( @entity341 ). MEASUREMENTS: A physical examination followed by three measurements of respiratory resistance by forced oscillation were obtained at 8 Hz (Rfo8) and at 16 Hz (Rfo16). In cooperative @entity1 , routine spirometry that included FEV1 was also performed on the Custo Vit R (Custo Med; Munich, Germany). All measurements were obtained twice during the course of the @entity341 treatment, before and after treatment with nebulized bronchodilators. RESULTS: The Rfo8 and Rfo16 measurements were highly reproducible (reproducibility coefficients >0.85). Both the Rfo8 and Rfo16 were at least as responsive to change (responsiveness coefficients of 2.3 and 1.2, respectively) as was FEV1 (2.0) and the four clinical signs most sensitive to change (0.6 to 1.0). A 19% change in Rfo8 was suggestive of significant reversibility. CONCLUSIONS: In the assessment of @entity1 aged > or =3 years with @entity697 , the respiratory resistance measurements are highly reproducible and responsive to change, particularly when obtained at 8 Hz. A 19% change from baseline Rfo8 is suggestive of reversibility. This technique appears to be an attractive alternative in the evaluation of @entity1 who are too young or too sick to perform spirometry reproducibly.

Respiratory resistance in the XXXX : a reproducible and responsive measure of @entity565 severity.

@entity1 :: ('9606', 'Species') :: ['children'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute asthma exacerbation'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity341 :: ('MESH:D004630', 'Disease') :: ['emergency department', 'ED'] @entity1224 :: ('MESH:D000402', 'Disease') :: ['airway obstruction']
@entity341 :: (MESH:D004630,Disease) :: ['emergency department']
