AIM: This retrospective study aimed to investigate the effect of @entity5173 ( @entity5173 ) in the management of @entity174 @entity1 with internal fixation instrument exposure caused by early @entity86 after open reduction and internal fixation (ORIF). METHODS: Fourteen @entity1 (11 @entity1 , 3 @entity1 , age range 9-63 years) with spinal and extremities @entity174 were enrolled in this study, including atlanto-axial @entity174 (N.=1), thoraco-lumbar @entity174 (N.=1), humerus @entity174 (N.=1), @entity3330 (N.=2), humerus @entity174 together with @entity3330 (N.=1), @entity174 of @entity2091 and @entity17630 (N.=3), L1 @entity174 together with @entity2091 and @entity17630 @entity174 (N.=2), L1 @entity174 (N.=2) and L1 @entity174 complicated by @entity2175 (N.=1). @entity281 occurred at the surgical incisions 1-7 days after ORIF operation. Deep spread of the infection caused exposure of internal fixation device. All @entity1 underwent local debridement with retention of internal fixation device. @entity5173 foam dressings containing the drainage tube were placed into the wound, covering external fixation devices and fully eliminating the dead space of soft tissue to avoid effusion. Continuous drainage and @entity5173 irrigation was performed for 24 h with regular replacement of @entity5173 . RESULTS: After 14-43 days of @entity5173 treatment, internal fixation devices were covered by healthy granulation tissue and complete wound healing was achieved. During a postoperative follow-up period of between 2 to 52 months, physical examinations and imaging studies of all @entity1 showed good functional recovery, no loosening of internal fixation devices, and no @entity281 . CONCLUSION: The use of @entity5173 , while retaining the internal fixation device can be safe and effective with earlier wound healing and functional recovery.

Application of XXXX in the treatment of internal fixation instrument exposure after early @entity86 .

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients'] @entity2175 :: ('MESH:D003924', 'Disease') :: ['type II diabetes'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures', 'fractured', 'vertebral fracture', 'fracture'] @entity2091 :: ('MESH:C535563', 'Disease') :: ['tibia'] @entity5173 :: ('MESH:D065634', 'Disease') :: ['vacuum sealing drainage', 'VSD'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Infections', 'systemic or local infection'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative infection'] @entity17630 :: ('MESH:C537349', 'Disease') :: ['fibula'] @entity3330 :: ('MESH:D005264', 'Disease') :: ['femoral fracture']
@entity5173 :: (MESH:D065634,Disease) :: ['vacuum sealing drainage']
