BACKGROUND: The purpose was to determine the factors influencing nodal involvement and topography of pelvic and paraaortic node @entity43 . STUDY DESIGN: Between 1985 and 2001, 276 @entity1 with @entity43 underwent systematic bilateral pelvic and paraaortic lymphadenectomy. RESULTS: The overall frequency of lymph node involvement was 44% (122 of 276). The frequency of pelvic and paraaortic @entity3 were 30% (82 of 276) and 40% (122 of 276), respectively. The frequency of lymph node @entity3 according to the stage of the disease (stages I, II, and III + IV) were: 20% (17 of 85), 40% (6 of 15), and 55% (99 of 176), respectively. In @entity1 with stage IA, IB, and @entity66 , the rates of nodal involvement were 13% (8 of 60), 33% (4 of 12), and 38% (5 of 13), respectively. None of 15 @entity1 with stage IA grade 1 disease had nodal involvement. None of the 20 @entity1 with @entity5 confined to the ovary(ies) (stage I disease) had nodal involvement. When paraaortic nodes were involved, the left paraaortic chain above the level of the inferior mesenteric artery was the most frequently involved site (70 @entity1 , 63%). One of nine @entity1 (11%) with a macroscopic stage I @entity5 and paraaortic involvement had contralateral @entity3 . CONCLUSIONS: Lymphadenectomy should be performed even in @entity1 with stage IA disease. This procedure could be omitted in @entity1 with mucinous apparent stage I disease and stage I grade 1 @entity5 . Lymphadenectomy should involve the whole pelvic and paraaortic chain up to the level of the left renal vein. A bilateral dissection should be performed even in cases of @entity1 with a @entity5 .

Lymph node involvement in XXXX : analysis of 276 pelvic and paraaortic lymphadenectomies and surgical implications.

@entity43 :: ('MESH:D010051', 'Disease') :: ['involvement in ovarian carcinoma', 'epithelial ovarian carcinoma'] @entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['IC disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['mucinous tumors', 'tumor', 'unilateral tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity43 :: (MESH:D010051,Disease) :: ['epithelial ovarian cancer']
