OBJECTIVES/HYPOTHESIS: Gamma knife radiosurgery (GKRS) has become an important treatment modality for @entity5513 . The primary aim of this study was to investigate whether @entity5 growth at the moment of GKRS has any correlation with the outcome. The secondary aim was to identify clinical predictors of radioresistance in @entity5513 @entity1 treated with GKRS. STUDY DESIGN: One hundred @entity5513 @entity1 , treated with GKRS, were divided into two groups: 1) proven @entity5 growth preceding GKRS; and 2) previous history of growth unknown. GKRS outcome was defined in two ways. According to the first definition, GKRS was said to have failed when additional treatment had taken place. According to the second one, a volume decrease >20% after 2 years marked successful treatment. METHODS: Correlations between outcome and growth status were determined with SPSS software. Furthermore, the study assessed how different variables ( @entity1 data, history, @entity5 characteristics, imaging, and audiovestibular examinations) correlated with the outcome of GKRS. RESULTS: No significant difference regarding success and failure of GKRS was found between the two @entity1 groups. The mean reduction in @entity5 volume after GKRS was less pronounced in @entity1 in whom @entity5 growth was demonstrated before treatment, but this finding was not significant. No significant predictors (P < .05) could be identified in this data set. CONCLUSIONS: This study found no indication that growth at the moment of GKRS influences therapeutic outcome, nor did it identify any predictors of the outcome after GKRS in @entity5513 @entity1 .

Gamma knife radiosurgery for @entity5513 : identification of predictors for continued XXXX growth and the influence of documented @entity5 growth preceding radiation treatment.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5513 :: ('MESH:D009464', 'Disease') :: ['vestibular schwannomas', 'vestibular schwannoma']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
