OBJECTIVE: To improve pathological understanding of massive @entity5861 . METHODS: Retrospective case series study. The clinical and pathological data of 7 cases of massive @entity5861 which were examined in the Pathological Department of Tianjin Eye Hospital from May 1988 to April 2012 were collected. The serial section of eyeball specimens were made with HE and PAS staining. The pathological section were reviewed under the light microscope. Analysis were made again combining with @entity1 ' clinical history, imaging findings and the pathological features. RESULTS: In 7 @entity1 , 6 @entity1 were male, 1 @entity1 was female. The age range was from 60 to 82 years old and the average age was 71.7 years old. Four cases were on the right eye and 3 cases were on the left eye. The main clinical feature was @entity1018 and 2 cases had @entity726 . Ultrasound examination showed @entity5 in 6 cases and @entity1713 with @entity548 in one case. The color Doppler ultrasound examination demonstrated @entity66 in 3 cases and two of them were detected with blood flow signal. The MRI were examined in 3 cases which showed iso-high signal in T1W1 and iso-low signal in T2W1 suggesting the @entity320 in 2 cases and @entity5861 in 1 case. Six cases were diagnosed clinically as @entity5 or @entity320 and 1 case was diagnosed as @entity2747 . The enucleation were performed in 7 cases. In these cases, 6 cases were diagnosed pathologically as @entity548 , @entity548 and massive @entity548 . The related @entity66 included soft drusen of Bruch membrane in 3 cases, choriocapillaris wall degeneration in 2 cases, fibrovascular membrane formation under RPE in 2 cases, @entity32 in 4 cases, choroidal vessels wall thickening and @entity1463 in 2 cases and @entity735 in one case. The secondary angle-closure @entity726 or angle-open @entity726 were accompanied respectively in 2 cases. Another case of 7 cases was diagnosed pathologically as the @entity2479 with massive @entity5861 . CONCLUSIONS: Massive @entity5861 liked to occur in the elderly male @entity1 . The main manifestations were sudden @entity227 . A small number of @entity1 had symptoms of @entity726 . Ophthalmic ultrasound and imaging characteristics were usually similar to the @entity68738 and were easily misdiagnosed as @entity320 . Pathological examination revealed that the main reasons of massive @entity548 were from the @entity548 and the @entity2479 .

[Clinical and pathological observation of seven cases of spontaneous XXXX ].

@entity1 :: ('9606', 'Species') :: ['patient', 'patients'] @entity1018 :: ('MESH:D054062', 'Disease') :: ['sudden loss of vision'] @entity32 :: ('MESH:D007249', 'Disease') :: ['choroidal chronic non-granulomatous inflammation'] @entity2747 :: ('MESH:D015812', 'Disease') :: ['acute angle-closure glaucoma'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual loss'] @entity66 :: ('MESH:D004194', 'Disease') :: ['choroidal lesions', 'choroidal substantive occupying lesion'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage', 'subretinal hemorrhage', 'hemorrhagic RPE detachment', 'vitreous hemorrhage'] @entity2479 :: ('MESH:D012173', 'Disease') :: ['rupture of retinal macroaneurysm'] @entity5 :: ('MESH:D009369', 'Disease') :: ['choroidal tumor'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['retinal detachment'] @entity68738 :: ('MESH:D002830', 'Disease') :: ['choroidal substantive neoplasm'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma', 'acute glaucoma', 'acute glaucoma symptoms'] @entity1463 :: ('MESH:D012598', 'Disease') :: ['sclerosis'] @entity735 :: ('MESH:D005124', 'Disease') :: ['choroidal vessels anomaly'] @entity5861 :: ('MESH:D012166', 'Disease') :: ['sub-retinal hemorrhage'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma', 'choroidal melanoma']
@entity5861 :: (MESH:D012166,Disease) :: ['sub-retinal hemorrhage']
