INTRODUCTION: @entity1186 in @entity583 ( @entity583 ) is a dynamic process often preceded by episodes of silent @entity397 and subocclusive @entity715 . @entity715 organization is achieved by ingrowth of endothelial and smooth muscle cells. Clinical significance and impact of @entity715 on primary percutaneous coronary intervention (pPCI) outcome remain unclear. Therefore we investigated composition and @entity2295 of thrombi aspirated during pPCI and their association with clinical and angiographic parameters of @entity583 @entity1 . METHODS: Aspirated thrombi retrieved from 84 @entity583 @entity1 were classified as fresh (<1day), lytic (1-5days) or organized (>5days). @entity715 was evaluated immunohistochemically using @entity2280 , @entity2279 and @entity7 antibodies. @entity2280 and @entity2279 immunopositive ( @entity2280 / @entity2279 +) cells were organized as single, clusters and microvessels. @entity7 positivity was graded as low or high, based on @entity715 surface immunopositive area. RESULTS: @entity2280 / @entity2279 + cells were present in 67% of all aspirated thrombi. @entity715 @entity2280 / @entity2279 positivity was associated with previous history of @entity951 (  (2)=6.142, p=0.013) and lower myocardial blush grade ( @entity7584 <3,   (2)=12.602, p<0.001). Organization of @entity2280 / @entity2279 + cells showed inverse association with the extent of @entity7 positivity (  (2)=10.607, p=0.005). Fresh thrombi were associated with shorter ischemic time (U=237.5, p=0.002) and @entity7584 3 (  (2)=6.379, p=0.012). CONCLUSIONS: Older @entity715 age and @entity2295 are associated with suboptimal myocardial perfusion in @entity583 @entity1 . @entity715 @entity7 expression is inversely associated with degree of @entity2280 + cell organization. Therefore, @entity2295 of aspirated thrombi may indicate the duration of @entity715 , coronary microcirculation status and outcome in @entity583 @entity1 .

Coronary thrombi neovascularization in @entity1 with XXXX - clinical and angiographic implications.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity7 :: ('7422', 'Gene') :: ['VEGF'] @entity7584 :: ('11269', 'Species') :: ['MBG'] @entity2295 :: ('MESH:D015861', 'Disease') :: ['neovascularization'] @entity2279 :: ('5175', 'Gene') :: ['CD31'] @entity397 :: ('MESH:D012421', 'Disease') :: ['plaque rupture'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina pectoris'] @entity2280 :: ('947', 'Gene') :: ['CD34'] @entity1186 :: ('MESH:D003328', 'Disease') :: ['Coronary artery thrombosis'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST-elevation myocardial infarction'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus neovascularization', 'Thrombus neovascularization', 'thrombosis', 'thrombus', 'Thrombus']
@entity583 :: (MESH:D009203,Disease) :: ['ST-elevation myocardial infarction']
