PURPOSE: Eighty percent of local recurrence after resection of @entity420 classically occurs within two years of surgery. Pretherapeutic staging is frequently limited to clinical examination, although the accuracy of endoanal ultrasonography has been demonstrated. The aim of this study was to report the long-term results of preoperative radiation therapy and resection of pretherapeutic endoanal ultrasonography-staged T3 and T4 @entity420 . METHODS: This retrospective review analyzed a series of 113 @entity1 who underwent radiation therapy followed by surgery. All @entity1 underwent an endoanal ultrasonography. Median follow-up was 75 months. RESULTS: Fifty-seven percent of @entity1 were pT3 or T4. Thirty-six percent had involvement of lymph nodes. Five-year rates of survival, local recurrence-free survival, and disease-free survival were 79, 73, and 68 percent, respectively. Ten-year rates were 65, 63, and 62 percent, respectively. Median time to detection of local recurrence was 39 months. Eight of ten local recurrences occurred after two years of follow-up. Eight of ten @entity1 with local recurrence had pretherapeutic endoanal ultrasonography-staged N+ @entity5 . CONCLUSION: These results appear to justify a follow-up program for @entity1 with pretherapeutic endoanal ultrasonography-staged N+ @entity5 . However, a minimum of seven years of follow-up is needed to obtain an accurate assessment of results.

Long-term results of preoperative radiotherapy for 113 cases of UT3 and UT4 XXXX : a need for long-term follow-up.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity420 :: ('MESH:D000230', 'Disease') :: ['rectal adenocarcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors']
@entity5 :: (MESH:D009369,Disease) :: ['rectal cancer']
