OBJECTIVE: Primary @entity5426 ( @entity5426 ) is rare without a reported series evaluating these @entity5 . STUDY DESIGN/METHODS: Five @entity1 with @entity5426 were retrospectively retrieved from the Otorhinolaryngic Registry of the Armed Forces Institute of Pathology. RESULTS: Three @entity1 and 2 @entity1 , aged 29 to 71 years, presented with hoarseness (n = 4) and hemoptysis (n = 1). Two @entity1 had previous neck radiation. The @entity5 involved the supraglottis (n = 4) with a mean size of 3.1 cm. Histologically, all @entity5 had anastomosing vascular channels lined by remarkably atypical endothelial cells protruding into the lumen, frequent atypical @entity6578 , and @entity548 . All cases tested (n = 4) demonstrated immunoreactivity with antibodies to Factor VIII-RA and @entity2280 . All @entity1 had surgery followed by postoperative radiation (n = 3 @entity1 ). Three @entity1 died with disease (mean, 17 mo), whereas one @entity1 is alive with no evidence of disease at 18 years. CONCLUSIONS: @entity5426 is a rare @entity5 , frequently associated with previous radiation, usually involving the supraglottis with characteristic histomorphologic and immunophenotypic features. @entity5426 has a poor prognosis, making appropriate separation from other conditions important.

XXXX : a clinicopathologic study of five cases with a review of the literature.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity5426 :: ('MESH:D006394', 'Disease') :: ['laryngeal angiosarcoma', 'LA'] @entity6578 :: ('MESH:C536987', 'Disease') :: ['mitotic figures'] @entity2280 :: ('947', 'Gene') :: ['CD34']
@entity5426 :: (MESH:D006394,Disease) :: ['Laryngeal angiosarcoma']
