BACKGROUND AND PURPOSE: Hemispheric location might influence outcome after @entity1779 ( @entity1779 ). INTERACT suggested higher short-term mortality in right hemispheric @entity1779 , yet statistical imbalances were not addressed. This study aimed at determining the differences in long-term functional outcome in @entity1 with right- vs. left-sided @entity1779 with a priori-defined sub-analysis of lobar vs. deep bleedings. METHODS: Data from a prospective hospital registry were analyzed including @entity1 with @entity1779 admitted between January 2006 and August 2014. Data were retrieved from institutional databases. Outcome was assessed using the modified Rankin Scale (mRS) score. Outcome measures (long-term mortality and functional outcome at 12 months) were correlated with @entity1779 location and hemisphere, and the imbalances of baseline characteristics were addressed by propensity score matching. RESULTS: A total of 831 @entity1 with supratentorial @entity1779 (429 left and 402 right) were analyzed. Regarding clinical baseline characteristics in the unadjusted overall cohort, there were differences in disfavor of right-sided @entity1779 (antiplatelets: 25.2% in left @entity1779 vs. 34.3% in right @entity1779 ; p < 0.01; previous @entity385 : 14.7% in left @entity1779 vs. 19.7% in right @entity1779 ; p = 0.057; and presence/extent of @entity548 : 45.0% in left @entity1779 vs. 53.0% in right @entity1779 ; p = 0.021; Graeb-score: 0 [0-4] in left @entity1779 vs. 1 [0-5] in right @entity1779 ; p = 0.017). While there were no differences in mortality and in the proportion of @entity1 with favorable vs. unfavorable outcome (mRS 0-3: 142/375 [37.9%] in left @entity1779 vs. 117/362 [32.3%] in right @entity1779 ; p = 0.115), @entity1 with left-sided @entity1779 showed excellent outcome more frequently (mRS 0-1: 64/375 [17.1%] in left @entity1779 vs. 43/362 [11.9%] in right @entity1779 ; p = 0.046) in the unadjusted analysis. After adjusting for confounding variables, a well-balanced group of @entity1 (n = 360/hemisphere) was compared showing no differences in long-term functional outcome (mRS 0-3: 36.4% in left @entity1779 vs. 33.9% in right @entity1779 ; p = 0.51). Sub-analyses of @entity1 with deep vs. lobar @entity1779 revealed also no differences in outcome measures (mRS 0-3: 53/151 [35.1%] in left deep @entity1779 vs. 53/165 [32.1%] in right deep @entity1779 ; p = 0.58). CONCLUSION: Previously described differences in clinical end points among @entity1 with left- vs. right-hemispheric @entity1779 may be driven by different baseline characteristics rather than by functional deficits emerging from different hemispheric functions affected. After statistical corrections for confounding variables, there was no impact of hemispheric location on functional outcome after @entity1779 .

Functional Long-Term Outcome after Left- versus Right-Sided Intracerebral XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['ICH', 'intracerebral hemorrhage'] @entity548 :: ('MESH:D006470', 'Disease') :: ['intraventricular hemorrhage'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity548 :: (MESH:D006470,Disease) :: ['Hemorrhage']
