BACKGROUND: Otogenic paediatric @entity50 ( @entity50 ) is rare but has potential clinical sequelae. Its management has long been debated mainly concerning the role of surgery and the use of anticoagulant therapy. OBJECTIVE OF REVIEW: To review the current literature and examine the medical and surgical management of paediatric otogenic @entity50 and its clinical and radiological outcome. TYPE OF REVIEW: Systematic review. SEARCH STRATEGY: The electronic databases (MEDLINE, EMBASE, Cochrane) were searched from inception to November 2014 using text words ' @entity50 OR @entity50 ' AND 'otogenic OR @entity2267 OR @entity2346 media' AND ' @entity1 OR paediatric OR pediatric'. EVALUATION METHOD: Inclusion criteria were applied by two reviewers and data extraction was carried out. The type of otological surgery (conservative versus extensive) and the use of anticoagulants with their clinical and radiological outcomes were tabulated. RESULTS: Thirty-six studies (15 case reports and 21 case series) were included with a total of 190 @entity1 . A total of 92.1% of @entity1 underwent otological surgery, and 69.5% had conservative surgery and 30.5% extensive otological surgery. Anticoagulants were used in 59%. A total of 79.2% of @entity1 were reported to have had a good clinical outcome. Within this group, 56% had conservative surgery and anticoagulants. Follow-up scans were documented in 61.6% of @entity1 and complete recanalisation was observed in 51%. Complete recanalisation was observed in 47% of those who had been anticoagulated and 55% of those who received no anticoagulation. CONCLUSIONS: Conservative otological surgery with the combination of anticoagulation was the most common treatment modality found in the group of @entity1 with good clinical outcome. However, given the current low level of evidence, a multicentre collaborative study is needed to help establish the optimum surgical approach and the role of anticoagulation in managing paediatric otogenic @entity50 .

Management of paediatric XXXX : a systematic review.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity50 :: ('MESH:D012851', 'Disease') :: ['cerebral venous thrombosis OR lateral sinus thrombosis OR sigmoid sinus thrombosis', 'cerebral venous sinus thrombosis', 'CVST'] @entity2346 :: ('MESH:D010031', 'Disease') :: ['otitis'] @entity2267 :: ('MESH:D008417', 'Disease') :: ['mastoiditis']
@entity50 :: (MESH:D012851,Disease) :: ['otogenic cerebral venous sinus thrombosis']
