OBJECTIVE: This study was designed to investigate the correlation factors for occurrence and progression-free survival of @entity1 with cavitating @entity2 . METHODS: We collected the clinical data of 947 @entity2 @entity1 . Tumor cavitation was observed in 51 @entity1 at baseline and in 23 @entity1 after treatment, while was not discovered in other 873 @entity1 . Multifactor logistic regression was performed to analyze the correlation factors for occurrence. The independent predictors of PFS were analyzed with Cox proportional regression. Survival curves were constructed with the Kaplan-Meier product limit method and compared using the log-rank test. RESULTS: In the 947 cases, the proportion of cases with baseline cavitation was 5.4% and the incidence of cavitation after treatment was 2.6%. Multivariate logistic regression analysis revealed that the occurrence of baseline cavitation is related to age, history of @entity6 , history of drinking, pathologic types, @entity5 location, @entity5 diameter and distant @entity3 (P < 0.05). Multifactor logistic regression analysis revealed that the occurrence of post-therapeutic cavitation is related to sex, pathologic types and @entity5 diameter (P < 0.05).The median PFS of @entity1 with baseline cavitation (7.3 months) was significantly longer than the cases without it (5.2 months) (P = 0.002). While there was no significant difference between the median PFS of @entity1 with post-therapeutic cavitation and @entity1 without it (5.1 months vs. 5.3 months, P = 0.060). Cox proportional regression analysis revealed that cyfra21-1 is related to PFS of @entity1 with baseline cavitaion (P < 0.05) and smoking history is related to PFS of @entity1 with post-therapeutic cavitaion (P < 0.05). CONCLUSIONS: @entity1 with baseline and post-therapeutic cavitation present different clinical features and progression-free survivals. The PFS of @entity1 with baseline cavitation is longer than that of the cases without it. On the contrary, PFS of @entity1 with post-therapeutic cavitation is shorter than the @entity1 without it.

[Analysis of correlation factors for occurrence and progression-free survival of cavitating XXXX in 947 cases].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity2 :: (MESH:D008175,Disease) :: ['lung cancer']
