OBJECTIVE: To assess the feasibility of undertaking a high-quality randomised controlled study to determine whether EA gives better control of delayed chemotherapy-induced @entity1209 (CINV) than sham EA or standard antiemetic treatment alone. METHODS: @entity1 having their first cycle of moderately or highly emetogenic chemotherapy were randomised to EA, sham EA or standard care. EA was given for 30   min on day 1 at the time of chemotherapy and on day 3 using standard acupuncture points bilaterally. Sham EA was given to points adjacent to true EA points. All @entity1 received usual care, comprising antiemetics, according to hospital guidelines. The primary outcomes related to study feasibility, and the clinical outcome measure was the change in Functional Living Index Emesis (FLIE) score captured on days 1 and 7. RESULTS: 153 @entity1 were screened between April 2009 and May 2011. Eighteen @entity1 did not meet the inclusion criteria, 37 declined to participate and the absence of an acupuncturist or lack of consent from the treating oncologist excluded a further 38 @entity1 ; 60 @entity1 were recruited. The FLIE was completed on day 7 by 49 @entity1 ; 33 of 40 @entity1 returned on day 3 for treatment. The @entity1209 scores were low in all three arms. Adverse events were generally mild and infrequent. CONCLUSIONS: It was feasible to undertake a randomised EA trial on a busy day oncology unit. As few @entity1 experienced @entity390 with their first cycle of chemotherapy, it was not possible to determine whether EA improves CINV over standard care. An enriched enrolment strategy is indicated for future studies. A simple numerical rating scale may prove a better objective @entity390 measure than the FLIE. TRIAL REGISTRATION NUMBER: ACTRN12609001054202.

EA versus sham acupuncture and no acupuncture for the control of acute and delayed chemotherapy-induced XXXX : a pilot study.

@entity1 :: ('9606', 'Species') :: ['participants', 'Patients', 'patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity1209 :: ('MESH:D020250', 'Disease') :: ['nausea and vomiting']
@entity1209 :: (MESH:D020250,Disease) :: ['nausea and vomiting']
