OBJECTIVE: To review the clinical, psychometric, laboratory, and radiologic findings of 6 @entity1 with @entity12287 ( @entity12287 ) who presented with @entity73 rather than @entity64 . DESIGN AND METHODS: Case series. All @entity1 fulfilled were diagnosed as @entity12287 based on the co-occurrence of livedo racemosa and @entity16 . @entity1 presenting with clinical @entity64 were excluded. RESULTS: @entity1 presented with cognitive complaints at an early age and all noted @entity272 from 6 months to 10 years before onset of @entity73 . Associated systemic disorders included @entity101 and @entity410 . Laboratory evidence of a hypercoagulable @entity558 was identified in 4 of 6 cases. Brain MRI scans demonstrated @entity194 , especially in parieto-occipital regions and cerebral blood flow on brain SPECT scan was reduced in a similar distribution. CONCLUSION: @entity1 with @entity12287 can develop @entity303 without antecedent clinical @entity64 . While the specific pathogenic mechanism of @entity303 in @entity12287 remains speculative, the disease predominantly injures brain tissue in vascular "watershed" territories.

@entity12287 : a cause of XXXX in young adults.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity558 :: ('MESH:C536528', 'Disease') :: ['condition'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive dysfunction', 'cognitive symptoms'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic disease'] @entity12287 :: ('MESH:D018860', 'Disease') :: ['SS', "Sneddon's syndrome"] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesions']
@entity73 :: (MESH:D003072,Disease) :: ['cognitive decline']
