OBJECTIVES: The objectives of this study were to evaluate the efficacy of minimally invasive ablation of high-risk large @entity44 ( @entity44 ) and to compare the efficacy of vascular and @entity5 ablation. METHODS: This was a retrospective multicenter study including a cohort of fetuses with high-risk large SCTs between 2004 and 2010. In addition, we performed a systematic literature review of all cases that underwent @entity5 ablation in order to compare the survival rates after 'vascular' and 'interstitial' ablation. Statistical analysis was conducted using Bayesian methods. RESULTS: In our cohort, a total of 13 fetuses had high-risk large @entity44 and five of them underwent @entity5 ablation. The estimated difference in hydrops resolution rate between the fetal intervention and the no fetal intervention groups was 44.6% (95% credibility interval, 1.5 to 81.0%; Pdiff> 0 = 97.9%). The estimated difference in survival rate between the fetal intervention and the no fetal intervention groups was 31.0% (13.9 to 48.1%; Pdiff> 0 = 99.9%). We analyzed our five cases together with 28 cases from the literature and estimated the difference in survival rate between the vascular and interstitial ablation groups as 19.8% (-13.1 to 50.1%; Pdiff> 0 = 88.3%). The estimated difference in hydrops resolution rate between the vascular and the interstitial ablation groups was 36.7% (-5.7 to 72.7%; Pdiff> 0 = 95.5%). CONCLUSION: Minimally invasive surgery seems to improve perinatal outcome in cases of high-risk large fetal @entity44 . Our findings suggest that 'vascular' ablation may improve outcome and may be more effective than 'interstitial' @entity5 ablation, but this hypothesis needs further investigation in a larger multicenter prospective study. Copyright    2015 ISUOG. Published by John Wiley _ Sons Ltd.

Technical aspects and effectiveness of percutaneous fetal therapies for large XXXX : cohort study and literature review.

@entity5 :: ('MESH:D009369', 'Disease') :: ['interstitial tumor', 'tumor'] @entity44 :: ('MESH:D013724', 'Disease') :: ['SCT', 'sacrococcygeal teratomas']
@entity44 :: (MESH:D013724,Disease) :: ['sacrococcygeal teratomas']
