BACKGROUND: Constipation affects up to 28% of Americans in 4 pathophysiologic patterns: @entity73 , a combination of both, and normal colon transit with normal pelvic floor function. Constipation may be a part of a generalized gastrointestinal (GI) tract transit disorder. The purposes of this study were to determine the percentage of @entity1142 @entity1 with the different pathophysiologic subtypes and and to evaluate what percentage of @entity1142 @entity1 has a diffuse GI tract transit disorder. METHODS: This was a retrospective analysis of 212 @entity1 who underwent anorectal manometry for intractable @entity1142 . Results of anorectal manometry, electromyography, balloon expulsion testing, defecography, and whole-gut transit scintigraphy were reviewed. RESULTS: Of 212 @entity1 included in the analysis, 91 (42%) had slow transit @entity1142 , 25 (12%) had dyssynergic defecation, 53 (25%) had both, and 43 (20%) had neither. Of @entity1 (91) with slow transit @entity1142 alone, 31 (34%) had delayed @entity356 , 9 (10%) had delayed small bowel transit, 7 (8%) had a delay in both, and 41 (48%) had normal upper GI tract transit. A similar distribution of upper GI tract transit disorders was observed for @entity1 with dyssynergic defecation, @entity73 , and normal colon transit with normal pelvic floor function. CONCLUSIONS: @entity1 with @entity1142 have a range of @entity1049 . The majority (80%) had @entity73 , or a combination of @entity73 . In addition, many @entity1 (51%) with @entity1142 have a concurrent @entity344 .

XXXX : more than a simple @entity1049 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity73 :: ('MESH:D003072', 'Disease') :: ['slow transit constipation, dyssynergic defecation', 'slow transit constipation and dyssynergic defecation'] @entity344 :: ('MESH:D005767', 'Disease') :: ['upper GI tract transit disorder'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['chronic idiopathic constipation', 'constipated', 'constipation'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric emptying'] @entity1049 :: ('MESH:D003108', 'Disease') :: ['colonic motor disorders']
@entity1142 :: (MESH:D003248,Disease) :: ['Chronic idiopathic constipation']
