PURPOSE: To report an unusual case of bilateral @entity14417 in @entity60623 . METHODS: Systematic analysis and description of relevant clinical features, histopathological, and genetic findings. RESULTS: A @entity4837 , born after 34 weeks of gestation, presented with typical features of @entity60623 and bilateral corneal opacification with central clearing. @entity60623 was confirmed by the identification of a homozygous mutation in the @entity60622 gene. When a flat anterior chamber was observed and perforation was suspected both corneas necessitated corneal transplantation (left @entity267 transplanted at 4 weeks of age, right @entity267 at the age of 9 weeks). Histopathological analysis of the left @entity267 revealed a central defect with absence of all corneal layers except for the corneal epithelium. The right @entity267 revealed central absence of the corneal endothelium and Descemet membrane as well, but the central stroma consisted of a cellular meshwork rich in fibroblasts. There were no signs of @entity22958 . CONCLUSIONS: We report the histopathology of serially obtained left and right @entity267 of a @entity4837 with @entity60623 . As demonstrated in the left @entity267 , the @entity1 had a central defect of all corneal layers except for the corneal epithelium. Histopathological analysis of the right @entity267 obtained 5 weeks later revealed that the defect had induced fibrovascular tissue repair. The sequence of events we report in the corneas of our @entity1 may help to better understand the pathogenesis of corneal (and anterior chamber) abnormalities in @entity60623 .

Unique Presentation of Corneal Opacity in @entity60623 : An Unusual Form of XXXX Showing Tissue Repair in Serial Analysis.

@entity1 :: ('9606', 'Species') :: ['patient', 'child'] @entity267 :: ('MESH:D065306', 'Disease') :: ['cornea'] @entity4837 :: ('MESH:D007567', 'Disease') :: ['premature neonate'] @entity60622 :: ('145173', 'Gene') :: ['B3GALTL'] @entity22958 :: ('MESH:D057129', 'Disease') :: ['iridocorneal or keratolenticular adhesions'] @entity60623 :: ('MESH:C537617', 'Disease') :: ['Peters Plus syndrome'] @entity14417 :: ('MESH:C537884', 'Disease') :: ['Peters anomaly']
@entity14417 :: (MESH:C537884,Disease) :: ['Peters Anomaly']
