CONTEXT: @entity1058 ( @entity1058 ) is widely used to treat @entity2023 ( @entity2023 ), however, evidence of efficacy is lacking. OBJECTIVE: To evaluate the efficacy of a Chinese herbal formulation for the treatment of @entity2023 . DESIGN: Randomized, double blind, placebo controlled trial. SETTING: RMIT Chinese Medicine Clinic. @entity1 : 55 @entity1 with @entity2023 (active 28, placebo 27). INTERVENTIONS: @entity1058 extract capsule (containing 18 herbs) or placebo, given daily for 8 weeks. MAIN OUTCOME MEASURES: The primary measure of efficacy were changes in severity of nasal and non-nasal symptoms using a Five Point Scale (FPS) measured by both @entity1 and the practitioner. The secondary measure was the change in score for the domains measured in the @entity7370 and @entity2490 Quality of Life Questionnaire (RQLQ) assessed by @entity1 . RESULTS: Forty-nine @entity1 completed the study (active 24, placebo 25). After eight weeks, the severity of nasal symptoms and non-nasal symptoms were significantly less in the active treatment group than in the control group, both for measurements made by @entity1 and those by the practitioner. Comparison of active and placebo treatment groups RQLQ scores also indicated significant beneficial effects of treatment (end point Section 1: P < 0.05; Section 2: P < 0.01). Intention-to-treat analyses of categorical items showed moderate to marked improvement rates were 60.7% and 29.6% for active and placebo respectively. Eleven @entity1 reported mild adverse events including 1 withdrawn from the trial. CONCLUSIONS: This @entity1058 formulation appears to offer symptomatic relief and improvement of quality of life for some @entity1 with @entity2023 .

Treatment for @entity2023 by XXXX : a randomized placebo controlled trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity7370 :: ('OMIM:613207', 'Disease') :: ['Rhinoconjunctivitis'] @entity2023 :: ('MESH:D006255', 'Disease') :: ['SAR', 'seasonal allergic rhinitis'] @entity2490 :: ('MESH:D012220', 'Disease') :: ['Rhinitis'] @entity1058 :: ('MESH:C562377', 'Disease') :: ['CHM', 'Chinese herbal medicine']
@entity1058 :: (MESH:C562377,Disease) :: ['Chinese herbal medicine']
