BACKGROUND: The incidence of @entity2969 ( @entity2969 ) in the United States is notably higher among white @entity1 versus other @entity1 . Previously, however, it was reported that rates were rising among Hispanics in certain areas. To determine whether this finding was evident in a wider area of the United States, data from 39 US @entity5 registries were examined. METHODS: Racial/ethnic-specific incidence rates per 100,000 @entity1 -years were calculated overall and by census region for the period of 1998-2011. Annual percentage changes (APCs) were estimated, and joinpoint models were fit. Differences in incidence by region were examined with the Wald test. RESULTS: From 1998 to 2011, 88,993 @entity2969 were recorded. The @entity2969 incidence was highest @entity62 (6.57 per 100,000), who were followed by Hispanics (3.88), American Indians/Alaska Natives (2.88), Asians/Pacific Islanders (A/PIs; 1.60), and @entity7864 (1.20). The incidence significantly increased among Hispanics ( @entity62 , 2.31; P   <   .0001), with rates rising in all regions except the South. Rates rose slightly @entity62 ( @entity62 , 0.51; P   =   .0076). Significant differences in rates by region were seen for Hispanics (P   =   .0001), @entity62 (P   <   .0001), and A/PIs (P   <   .0001), with the highest rates among Hispanics in the West and with the highest rates @entity62 and A/PIs in the Northeast. CONCLUSIONS: Although the incidence of @entity2969 remained highest @entity62 between 1998 and 2011, the greatest increase was experienced by Hispanics. Rising rates of @entity2969 among Hispanics in the United States suggest that future attention is warranted. Reasons for the increase may include variability in birthplace, changing exposures, genetic susceptibility, and the length of US residence. @entity5 2015;121:4181-4189.    2015 American @entity5 Society.

Incidence of @entity2969 among US XXXX by census region.

@entity1 :: ('9606', 'Species') :: ['man', 'men'] @entity7864 :: ('MESH:D055008', 'Disease') :: ['non-Hispanic blacks'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'Cancer'] @entity2969 :: ('MESH:C563236', 'Disease') :: ['testicular germ cell tumors', 'TGCTs', 'TGCT'] @entity62 :: ('MESH:D056784', 'Disease') :: ['among non-Hispanic whites', 'non-Hispanic whites', 'APC']
@entity1 :: (9606,Species) :: ['men']
