The optimal management strategy for @entity1 with @entity583 ( @entity583 ) and @entity66 has not been well established. In the present cohort study, we sought to examine the safety and efficacy of inhospital staged PCI for @entity1 with @entity583 . We identified all @entity1 with @entity583 referred for primary PCI who were found to have @entity66 ( @entity850 >= 50% in nonculprit vessel) and compared clinical outcomes in relation to the management strategy, staged versus culprit-only PCI, for nonculprit vessel disease. The primary outcome was mortality at 180  days, and secondary outcomes included mortality during the index hospitalization and at 30  days, @entity583 , stent @entity715 , @entity64 , and @entity548 . Of the 1,038 @entity1 with @entity583 meeting inclusion criteria, 259 (25%) underwent staged PCI and 779 (75%) culprit-only PCI during the index admission. Mortality at 180  days was 0.8% in @entity1 with staged PCI and 5.0% in @entity1 with culprit-only PCI (p  = 0.003). The association between staged PCI and reduced mortality persisted after adjusting for baseline differences in @entity1 characteristics and angiographic variables between the 2 cohorts (odds ratio 0.2, 95% confidence interval 0.04 to 0.77, p  = 0.02). The rates of inhospital reinfarction in the staged and culprit-only PCI cohorts were 0.8% versus 1.3% (p  = 0.50), respectively, stent @entity715 0.8% versus 1.3% (p  = 0.50), and @entity64 0.4% versus 1.3% (p  = 0.31). There were no inhospital adverse events related to acute occlusion of a nonculprit vessel in either cohort. Staged PCI during index admission is a safe and effective revascularization strategy for @entity1 with @entity583 .

Safety and Efficacy of Staged Percutaneous Coronary Intervention During Index Admission for ST-Elevation XXXX With Multivessel Coronary Disease (Insights from the University of Ottawa Heart Institute @entity583 Registry).

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity66 :: ('MESH:D004194', 'Disease') :: ['multivessel disease'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI and multivessel disease', 'STEMI', 'myocardial infarction', 'ST-elevation myocardial infarction'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity583 :: (MESH:D009203,Disease) :: ['Myocardial Infarction']
