OBJECTIVES: We evaluated cardiopulmonary function at rest and during exercise in @entity1 after surgical repair for total @entity358 . BACKGROUND: Long-term assessment of cardiopulmonary function during exercise in @entity1 after repair for total @entity358 during infancy is limited. METHODS: Resting lung function and cardiopulmonary function during maximal ramp cycle ergometry were evaluated in 27 @entity1 (age = 11 +/- 4 years, 20 were male). Peak @entity26 consumption, ventilatory anaerobic threshold, and physical working capacity were compared with normal reference values. Neurologic assessment included neuromuscular function, inattentiveness, and @entity2915 . @entity1 - and procedure-related variables were assessed for association with peak @entity26 consumption, ventilatory anaerobic threshold, and physical working capacity. RESULTS: Compared with healthy @entity1 , peak @entity26 consumption (88% +/- 16% of predicted) and ventilatory anaerobic threshold (91% +/- 21% of predicted) were mildly reduced. Chronotropic impairment was observed in 7 @entity1 (32%). @entity1 with impaired resting lung mechanics were more likely to have impairment in peak @entity26 consumption (P < .05). Breathing reserve was normal. Specific anatomy and all operative factors did not have a significant impact on overall exercise performance. Composite score for fine and gross motor function was associated with lower ventilatory anaerobic threshold (P < .05). CONCLUSIONS: Exercise performance is mildly impaired at long-term follow-up after total @entity358 repair during infancy. @entity358 are common and associated with lower exercise performance. @entity16 are evident in a subgroup, but the impact on late exercise performance is inconclusive.

Late cardiopulmonary and musculoskeletal exercise performance after repair for total XXXX during infancy.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'Patient'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity16 :: ('MESH:D009422', 'Disease') :: ['Neurologic abnormalities'] @entity358 :: ('MESH:D008171', 'Disease') :: ['Residual pulmonary abnormalities', 'anomalous pulmonary venous connection'] @entity2915 :: ('MESH:D006948', 'Disease') :: ['hyperactivity']
@entity358 :: (MESH:D008171,Disease) :: ['anomalous pulmonary venous connection']
