We conducted a two-stage study in France, Germany, Italy, Spain, Sweden, and the United Kingdom of the stated preferences of @entity1118 sufferers treated with classic strong opioids and of physicians treating such @entity1 . The qualitative stage identified attributes perceived important through focus groups with 84 @entity158 sufferers and semistructured interviews with 11 physicians. The quantitative stage included online, discrete choice experiments (DCEs) in which respondents chose between hypothetical profiles or an opt-out in 15 choice tasks. The profile descriptions were based on the attributes elicited in the qualitative stage. DCEs were conducted for @entity158 sufferers (N = 242) and physicians (N = 270) who passed a rationality test. Main-effects models were estimated by hierarchical Bayesian regression. Sufferers ranked @entity390 , @entity158 impact, energy, alertness, and @entity1142 ; physicians ranked @entity158 response, central nervous system (CNS) effects, @entity390 , dose form, and @entity1142 in descending order of importance. Sufferers were unwilling to incur severe side effects to decrease @entity158 and chose the opt-out in approximately one half of the choice tasks, whereas physicians were willing to trade between profiles. The models predicted physicians' choices better than those of @entity158 sufferers. No age, sex, or country effects were seen, but stronger preferences were found among physicians treating noncancer (n = 40) than @entity5 and among the 55% of sufferers who had never discontinued long-term @entity158 medication use. Sufferers' mean @entity158 scores on an 11-point Likert scale were 4.0, 5.7, and 8.6 on their best, average, and worst days, respectively.

Stated preferences of physicians and XXXX sufferers in the use of classic strong opioids.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer pain'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation'] @entity1118 :: ('MESH:D059350', 'Disease') :: ['chronic pain']
@entity1118 :: (MESH:D059350,Disease) :: ['chronic pain']
