OBJECTIVE: Endoscopic ablation of large rectal @entity652 is being increasingly used as primary treatment. Despite the avoidance of general anaesthesia and the prevention of more major procedures, @entity1 undergoing endoscopic ablation have the disadvantage of multiple treatment sessions and the lack of adequate tissue sample for complete histological study. The aim of this study was to analyse the outcome of all @entity1 with large @entity1127 treated with endoscopic ablation. @entity1 AND METHODS: Between 1993 and 1998, 29 @entity1 who underwent endoscopic ablation of large rectal @entity652 were identified. All their case notes were analysed and information was collected on recurrence, treatment episodes, complications, the incidence of @entity189 and the necessity for further procedures. RESULTS: At a median 40 (range 4-67) months follow-up, 41% of @entity1 had recurrence of their @entity652 and 14% had been diagnosed with @entity420 . Only 24% of @entity1 had been discharged while 21% were clear but were still under surveillance. Seven (24%) @entity1 had complications, 6 @entity850 and one severe @entity548 . All @entity850 occurred in @entity1 who had more than 10 treatment sessions. In all, 31% of @entity1 needed further endoanal or abdominal surgery and the median time to making this decision was 28 (range 4-66) months. There were no deaths. CONCLUSION: Laser and @entity3503 ablation of large rectal @entity652 has proved very disappointing. It should be reserved for @entity1 who are unfit to undergo general anaesthesia.

Outcome of XXXX beam and LASER ablation of large rectal @entity652 .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['rectal polyps'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas', 'adenoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity3503 :: ('MESH:D001128', 'Chemical') :: ['argon']
@entity3503 :: (MESH:D001128,Chemical) :: ['argon']
