AIM: To investigate whether the @entity15639 ( @entity15639 ) polymorphism is associated with @entity4570 in a Chinese population. METHODS: This study included 131 @entity1 with enterocutaneous/enteroatmospheric @entity292 . @entity1 with @entity29 or other @entity792 were excluded from this study. All @entity1 with enterocutaneous/enteroatmospheric @entity292 were followed up for three months to observe disease recurrence. In addition, a total of 140 healthy controls were also recruited from the Jinling Hospital, matched according to the sex and age of the @entity1 population. Genomic DNA was extracted from peripheral blood from each @entity1 . The @entity15639 restriction fragment length polymorphism related to the polymorphic @entity9379 site at position 1267 was characterized by polymerase chain reaction (PCR). First PCR amplification was carried out, and then PCR products were digested with @entity9379 restriction enzyme. The DNA lacking the polymorphic @entity9379 site within @entity15639 generates a product of 1117 bp in size (allele A), whereas the @entity15639 @entity9379 polymorphism produces two fragments of 936 bp and 181 bp in size (allele B). RESULTS: The frequency of the @entity15639 @entity9379 polymorphism did not differ between @entity1 and controls; however, the A allele was more predominant in @entity1 with @entity4570 than in controls (60.7% vs 51.4%, P = 0.038, OR = 1.425, 95%CI: 1.019-1.994). Sixty-one @entity1 were cured by a definitive operation, drainage operation, or percutaneous drainage while 52 @entity1 were cured by nonsurgical treatment. There was no significant difference in the frequency of the @entity15639 @entity9379 polymorphism between the @entity1 who had surgery compared to those who did not (P = 0.437, OR = 1.237, 95%CI: 0.723-2.117). Moreover, 11 @entity1 refused any treatment for economic reasons or @entity5 burden, and 7 @entity1 with @entity4570 (5.8%) died during the follow-up period. However, there was no significant difference in the frequency of the @entity15639 @entity9379 polymorphism between the @entity1 who survived compared to those who died (P = 0.403, OR = 0.604, 95%CI: 0.184-1.986). CONCLUSION: The A allele of the @entity15639 @entity9379 polymorphism was associated with @entity4570 in this Chinese population.

Polymorphism of XXXX and enterocutaneous @entity292 in Chinese population.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'participant', 'patient'] @entity15639 :: ('3306', 'Gene') :: ['HSP70-2', 'heat shock protein 70-2'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease'] @entity9379 :: ('6690', 'Gene') :: ['PstI'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistulas'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmune diseases'] @entity4570 :: ('MESH:D007412', 'Disease') :: ['enterocutaneous fistulas']
@entity15639 :: (3306,Gene) :: ['heat shock protein 70-2']
