BACKGROUND: Ischemic involvement of the right ventricle (RV) can complicate the early course of inferior ST elevation @entity583 (IMI) and has significant management implications but its diagnosis is difficult. This study assessed RV involvement in the acute and late phase of IMI by pulse-wave tissue Doppler (PW-TDI) and RV myocardial performance index (RVMPI). METHODS: We prospectively evaluated 38 @entity1 with first IMI, of whom 14 had RV involvement and 24 no RV involvement, as defined by ST segment elevation >= 0.1 mV in lead V4R. Thirty age-matched healthy subjects served as controls. Echocardiographic assessment included PW-TDI measurements from the lateral tricuspid annulus with MPI evaluation and was repeated at 6-month follow-up. RESULTS: Peak systolic velocity of the tricuspid annulus, S', was significantly lower and RVMPI higher in @entity1 with RVMI compared to @entity1 without RVMI and controls. @entity1 with @entity66 had lower S' and higher RVMPI than @entity1 with distal RCA or left coronary lesion. In the acute setting, the index S'/MPI < 17 was perfectly discriminatory for RV involvement and had moderate sensitivity and specificity (85%, 87%) for identifying proximal @entity66 . S'/MPI < 23 at 6 months had moderate-to-good sensitivity and specificity in identifying @entity1 with previous RVMI. CONCLUSIONS: Echocardiographic assessment of the RV by PW-TDI of the lateral tricuspid annulus, with derivation of MPI is a sensitive and specific marker of RV involvement in first IMI and remains so 6 months after the ischemic event. The novel index of S'/MPI appears to have potentially improved diagnostic accuracy in identifying RV involvement and @entity66 .

Tissue Doppler imaging of the tricuspid annulus and myocardial performance index in the evaluation of right ventricular involvement in the acute and late phase of a first XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity66 :: ('MESH:D004194', 'Disease') :: ['RCA disease', 'proximal RCA lesion']
@entity583 :: (MESH:D009203,Disease) :: ['inferior myocardial infarction']
