We aimed to determine the long term durability of silk suture and @entity4832 ( @entity939 ) particle embolization (SPE) of @entity2758 ( @entity2758 ), and to evaluate the outcomes following multimodality management of @entity2758 with combined SPE and stereotactic radiosurgery (SRS). A general supposition among neurointerventionalists is that embolization of @entity7026 with silk sutures and @entity939 particles does not yield a durable occlusion. We performed a retrospective review of all @entity2758 @entity1 treated at our institution with combined SPE and SRS. After extracting the baseline, embolization and SRS data for each @entity1 , the durability of SPE was determined by evaluating the postembolization recanalization between the last procedural angiogram and the most recent neuroimaging. Four @entity2758 @entity1 who underwent a total of nine SPE procedures through 21 arterial pedicles were included for the analyses. The nidus volumes were 5.8-75 cm(3) and the Spetzler-Martin grades were II and V in one @entity1 and III in two @entity1 . The median degree of devascularization per procedure was <25%. There were no procedural complications, with all @entity1 maintaining functional independence after embolization (modified Rankin scale score 0-2). After a median follow-up duration of 27 months (range: 23-36), there were no @entity1 with recanalization. SRS (marginal dose 13-18 Gy) resulted in 40 to >95% volume reduction. Following SRS, one @entity1 remained asymptomatic, two @entity1 improved, and one @entity1 deteriorated due to a latency period @entity548 . In conclusion, SPE can safely provide durable @entity2758 devascularization, therefore, appropriately selected nidi can be effectively treated with combined SPE and SRS.

Embolization of XXXX with silk suture particles prior to stereotactic radiosurgery.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity7026 :: ('MESH:D002538', 'Disease') :: ['cerebral AVM'] @entity939 :: ('CHEBI:17246', 'Chemical') :: ['PVA'] @entity2758 :: ('MESH:D001165', 'Disease') :: ['arteriovenous malformations', 'AVM'] @entity4832 :: ('MESH:D011142', 'Chemical') :: ['polyvinyl alcohol'] @entity548 :: ('MESH:D006470', 'Disease') :: ['AVM hemorrhage']
@entity7026 :: (MESH:D002538,Disease) :: ['cerebral arteriovenous malformations']
