INTRODUCTION: @entity18450 ( @entity18450 ) is a rapidly developing necrotizing @entity9156 that originates in genital and perineal region. The mortality rate is high and requires prompt diagnosis, antibiotic treatment and extensive necrosectomy with derivative colostomy. Vacuum Assisted Closure (VAC) is a wound care system of paramount importance in the treatment of complex wounds, including the perineum. MATERIALS AND METHODS: We evaluated 6 cases of @entity18450 (males, mean age: 54.6 yrs) of the last 3 years (February 2008-August 2010). All @entity1 were @entity6 . We used intravenous antibiotic treatment and early surgical debridement with colostomy, followed by immediate positioning of a VAC device (NP 125-200 mmHg). The dressing changes were done every 3-4 days. Hyperbaric @entity26 therapy (HBOT) was given only to one @entity1 . Microbiological etiology was assessed by multiple cultures to tailor the antimicrobial treatment. RESULTS: The VAC therapy reduces the number of dressings and the hospital length of stay (LOS), in agreement with the literature; in one of the cases a secondary reconstructive surgical intervention was possible. The colostomy was reversed in all @entity1 within 3 months. CONCLUSIONS: Negative pressure is a time saving device, reducing days of hospitalization, @entity1 's discomfort and number of medications. The possibility of a early reconstructive surgery improves significantly quality of life.

VAC (Vacuum Assisted Closure) treatment in XXXX : personal experience and literature review.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetics'] @entity18450 :: ('MESH:D018934', 'Disease') :: ['FG', "Fournier's gangrene"] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity9156 :: ('MESH:D005208', 'Disease') :: ['fasciitis']
@entity18450 :: (MESH:D018934,Disease) :: ['Fournier's gangrene']
