BACKGROUND: This study sought to evaluate the predictors of @entity5 in the 2012 international consensus guidelines for @entity4929 ( @entity4929 ) and validate their diagnostic value relative to the 2006 guidelines. METHODS: Between 2002 and 2014, 177 consecutive @entity1 who underwent curative resection of IPMN were reviewed. Based on the 2012 guidelines, high-risk stigmata (mural nodule with enhancement, main pancreatic duct [MPD]  >=   10  mm, and @entity3883 ) and worrisome features (cyst size  >=   30  mm, thickened cyst wall, mural nodule without enhancement, MPD 5-9  mm, an abrupt change in MPD diameter, and @entity3329 ) were assessed, and predictive and diagnostic values were analyzed statistically. RESULTS: Multivariate analysis identified @entity3883 (odds ratio [OR], 23.9; P  <  .0001), abrupt change in MPD diameter (OR, 3.01; P  =  .017) and @entity3329 (OR, 5.84; P  =  .027) as independent predictive factors, with an accuracy of 69.8, 67.4, and 66.3%, respectively. Operative intervention was indicated in 156 @entity1 (94.0%) using the 2006 guidelines, and in 130 (78.3%) using the 2012 guidelines. The accuracy of the 2006 guidelines was 35.5% compared with 44.8% for the 2012 guidelines. The area under the curve (AUC) for the 2006 and 2012 guidelines was 0.65 and 0.67, respectively;   AUC was 0.02, which was not statistically significant. When the worrisome features were combined with high-risk stigmata, the AUC increased to 0.79. CONCLUSION: @entity3883 , abrupt change in MPD diameter, and @entity3329 were independent predictive factors in the 2012 guidelines with high accuracy. Using the new guidelines, the number of @entity1 with IPMN managed with observation and the predictive accuracy increased.

Comparison of the international consensus guidelines for predicting @entity5 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3883 :: ('MESH:D041781', 'Disease') :: ['Obstructive jaundice', 'obstructive jaundice'] @entity3329 :: ('MESH:D008206', 'Disease') :: ['lymphadenopathy'] @entity4929 :: ('MESH:C565310', 'Disease') :: ['IPMNs', 'intraductal papillary mucinous neoplasms'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancy']
@entity4929 :: (MESH:C565310,Disease) :: ['intraductal papillary mucinous neoplasms']
