BACKGROUND: One of the most frequent complications of pancreaticoduodenectomy (PD) is delayed @entity356 (DGE). The study aim was to evaluate the impact of the type of gastro/duodenojejunal reconstruction (antecolic vs. retrocolic) after PD on DGE incidence. METHODS: A systematic review was made according to the PRISMA guidelines. Randomized controlled trials (RCTs) comparing antecolic vs. retrocolic reconstruction were included irrespective of the PD techniques. A meta-analysis was then performed. RESULTS: Six RCTs were included for a total of 588 @entity1 . The overall quality was good. General risk of bias was low. DGE was not statistically significantly different between the antecolic and retrocolic group (OR 0.6, 95% CI 0.31-1.16, p = 0.13). The other main surgery-related complications ( @entity3472 , @entity548 , @entity6177 , @entity1157 and @entity2737 ) were not dependent on the reconstruction route (OR 0.84, 95% CI 0.41-1.70, p = 0.63). No statistically significant difference in terms of length of hospital stay was found between the 2 groups. There was also no difference of DGE incidence if only pylorus-preserving PD was considered and between the DGE grades A, B or C. CONCLUSION: This meta-analysis shows that antecolic reconstruction after PD is not superior to retrocolic reconstruction in terms of DGE.

Effect of Antecolic versus Retrocolic Gastroenteric Reconstruction after Pancreaticoduodenectomy on Delayed XXXX : A Meta-Analysis of Six Randomized Controlled Trials.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity6177 :: ('MESH:D018784', 'Disease') :: ['intra-abdominal abscess'] @entity1157 :: ('MESH:D001649', 'Disease') :: ['bile leak'] @entity2737 :: ('MESH:D014946', 'Disease') :: ['wound infection'] @entity3472 :: ('MESH:D010185', 'Disease') :: ['pancreatic fistula'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric emptying']
@entity356 :: (MESH:D013274,Disease) :: ['Gastric Emptying']
