Dietary @entity1507 ( @entity8326 ) supplementation via beetroot juice has been shown to increase the exercise capacity of younger and older adults. The purpose of this study was to investigate the effects of acute @entity8326 ingestion on the submaximal constant work rate exercise capacity of @entity1030 @entity1 . Fifteen @entity1 were assigned in a randomized, single-blind, crossover design to receive one of two treatments (beetroot juice then placebo or placebo then beetroot juice). Submaximal constant work rate exercise time at 75% of the @entity1 's maximal work capacity was the primary outcome. Secondary outcomes included plasma @entity8326 and @entity3542 ( @entity6836 ) levels, blood pressure, heart rate, @entity26 consumption (VO2), dynamic hyperinflation, @entity1353 and leg discomfort. Relative to placebo, beetroot ingestion increased plasma @entity8326 by 938% and @entity6836 by 379%. Median (+interquartile range) exercise time was significantly longer (p = 0.031) following the ingestion of beetroot versus placebo (375.0 + 257.0 vs. 346.2 + 148.0 s, respectively). Compared with placebo, beetroot ingestion significantly reduced iso-time (p = 0.001) and end exercise (p = 0.008) diastolic blood pressures by 6.4 and 5.6 mmHg, respectively. Resting systolic blood pressure was significantly reduced (p = 0.019) by 8.2 mmHg for the beetroot versus the placebo trial. No other variables were significantly different between the beetroot and placebo trials. These results indicate that acute dietary @entity8326 supplementation can elevate plasma @entity8326 and @entity6836 concentrations, improve exercise performance, and reduce blood pressure in @entity1030 @entity1 .

Dietary @entity1507 supplementation improves exercise performance and decreases blood pressure in @entity1030 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity8326 :: ('CHEBI:29794', 'Chemical') :: ['NO3(-)'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity3542 :: ('CHEBI:16301', 'Chemical') :: ['nitrite'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1507 :: ('CHEBI:48107', 'Chemical') :: ['nitrate'] @entity6836 :: ('CHEBI:29785', 'Chemical') :: ['NO2(-)'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['COPD']
@entity1 :: (9606,Species) :: ['patients']
