@entity0 is certainly not preventable at the same degree as @entity2 is by avoiding cigarette smoking or @entity150 by avoiding exposure to some specific professional carcinogens. Despite the increased availability of screening mammography and the use of adjuvant chemotherapy, @entity0 remains a major cause of morbidity and mortality in @entity1 . Chemoprevention could be one of the possible weapons to decrease the morbidity and the mortality due to @entity0 . Experimental, epidemiological and clinical data suggest that one can prevent occurrence of @entity0 . The results of five trials including more than 25,000 @entity1 comparing the effectiveness of @entity440 with a placebo were published. The results of these trials, at first sight, do not agree. Only in the USA, the results of the five trials have led to licence @entity440 for chemoprevention of @entity0 . But the Food and Drug Administration stresses the fact that the noxious side effects are too numerous for this molecule to be prescribed with all the @entity1 . It must be reserved for the @entity1 presenting an increased risk. The means of identifying the @entity1 at increased risk are not yet perfect.

[Can XXXX be chemoprevented in 2003?].

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity440 :: ('MESH:D013629', 'Chemical') :: ['tamoxifen'] @entity0 :: ('MESH:D001943', 'Disease') :: ['Breast cancer', 'breast cancer'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity150 :: ('MESH:D001749', 'Disease') :: ['bladder cancer']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
