BACKGROUND: @entity296 can occur after @entity385 in the absence of primary cardiac causes. The neuroanatomic basis of @entity64 -related @entity296 is not well understood. OBJECTIVE: To identify regions of @entity4798 associated with @entity296 using a method free of the bias of an a priori hypothesis as to any specific location. METHODS: Of 738 consecutive @entity1 with acute @entity385 , the authors identified 50 @entity1 in whom serum @entity10020 ( @entity10020 ) elevation occurred in the absence of any apparent cause within 3 days of symptom onset. Fifty randomly selected, age- and sex-matched @entity1 with @entity385 without @entity10020 elevation served as controls. Diffusion-weighted images with outlines of @entity1188 were co-registered to a template, averaged, and then subtracted to find voxels that differed between the two groups. Voxel-wise p values were determined using a nonparametric permutation test to identify specific regions of @entity1188 that were associated with @entity10020 elevation. RESULTS: The study groups were well balanced with respect to @entity64 risk factors, history of @entity453 , @entity1188 volume, and frequency of right and left middle cerebral artery territory involvement. Brain regions that were a priori associated with @entity10020 elevation included the right posterior, superior, and medial insula and the right inferior parietal lobule. Among @entity1 with @entity2500 , the insular cluster was involved in 88% of @entity1 with and 33% without @entity10020 elevation (odds ratio: 15.00; 95% CI: 2.65 to 84.79). CONCLUSIONS: @entity1188 in specific brain regions including the right insula are associated with elevated serum @entity10020 level indicative of @entity296 .

Neuroanatomic correlates of @entity64 -related XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4798 :: ('MESH:D020520', 'Disease') :: ['brain infarction'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial injury', 'Myocardial injury'] @entity2500 :: ('MESH:D020244', 'Disease') :: ['right middle cerebral artery infarction'] @entity10020 :: ('7139', 'Gene') :: ['cTnT', 'cardiac troponin T'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['Infarctions', 'infarction'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity296 :: (MESH:D009202,Disease) :: ['myocardial injury']
