AIM: The aim of the study was to investigate the possible role of individual predisposition in the pathogenesis of carotid @entity256 . METHODS:Over 1700 @entity1 have undergone carotid endarterectomy (CEA) in our institute over the past 15 years. We retrospectively reviewed the charts of those who also had contralateral @entity3538 ( @entity3538 ) for primary @entity731 and recorded the rates of post-CEA and post- @entity3538 @entity256 >= 50%. RESULTS: In the 29 cases analyzed (21 @entity1 /8 @entity1 ), CEA was performed with conventional technique and direct suturing in most cases. Mean ages at the time of CEA and @entity3538 were 69.2  6.6 and 73  6.7 yrs, respectively, and risk profiles at the 2 time points were similar: @entity101 (96.5%), @entity2299 (55.2%), smoking (51.7%), @entity6 (31%), @entity453 (48.3%), @entity1030 (37.9%), and @entity177 (13.8%). Antiplatelet therapy protocols were identical for the two procedures. During follow-up (mean: 67.25  51.6 months after CEA, 24.6  16.9 months after @entity3538 ), Duplex scans revealed @entity256 in 12 @entity1 (9 arteries treated with CEA, 6 managed with @entity3538 ). In three @entity1 , @entity256 was bilateral. Restenosis-free survival rates at five years were 85% after CEA and 66% after @entity3538 (P=NS). CONCLUSION: In this selected group of @entity1 , CEA and @entity3538 were associated with a similar incidence of @entity256 . Only 25% of the @entity1 who developed @entity256 did so after both procedures. These preliminary findings indicate that individual predisposition does not play a crucial role in the pathogenesis of @entity256 . To confirm this conclusion, an analysis of a much larger, multicenter cohort is essential.

Conventional carotid endarterectomy versus stenting: comparison of XXXX rates in arteries with identical predisposing factors.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity3538 :: ('MESH:D002341', 'Disease') :: ['carotid stenting', 'CAS'] @entity256 :: ('MESH:D023903', 'Disease') :: ['restenosis'] @entity177 :: ('MESH:D051437', 'Disease') :: ['chronic renal failure'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic stenosis']
@entity256 :: (MESH:D023903,Disease) :: ['restenosis']
