AIM: To investigate the association of a single @entity1540 with physical, emotional, or meteorologic stress and the role of age, sex, antiarrhythmic and other medicament therapy and @entity1 characteristics. METHODS: The study included 457 @entity1 who were consecutively assigned to undergo continuous 24-hour Holter monitoring and who completed a structured questionnaire about their physical activity and mental stress. Multiple regression analysis of data on 11 meteorologic parameters, @entity1 ' baseline characteristics, and medications they used was performed for subgroups according to sex and age, with 65 years as age limit. RESULTS: Wind speed, low relative humidity, increasing relative humidity, and emotional stress were independent predictors of @entity1540 , whereas warm front passage showed a protective effect in all @entity1 subgroups (P<0.05 in all cases). Physical activity was an independent predictor of @entity1540 in @entity1 (P=0.02) and cold front passage in @entity1 P=0.003). The circadian variation in frequency of @entity1540 persisted in all subgroups after adjustments for external triggers (P<0.001 in all cases). Among chronic risk factors, familial background and previous @entity583 were independent predictors of @entity1540 in @entity1 and younger (P<0.05 in all cases). Nitrates (P<0.03 in all cases) and angiotensin converting enzyme inhibitors (P<0.02 in all cases) exerted protective effect in younger @entity1 as well as did beta-blockers in the elderly (P<0.003 in all cases). CONCLUSION: In addition to existence of an endogenous, external triggering-independent circadian pattern, physical, emotional, and meteorologic stress may act as triggers of @entity1540 in a manner that differs from triggering more complex @entity943 . Familial background seems to have a significant impact on arrhythmogenesis in @entity1 .

Triggering of XXXX by emotional, physical, and meteorologic stress: role of age, sex, medications, and chronic risk factors.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'participant', 'men'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity943 :: ('MESH:D001145', 'Disease') :: ['arrhythmias'] @entity1540 :: ('MESH:D018879', 'Disease') :: ['ventricular ectopic beat', 'ventricular ectopic beats']
@entity1540 :: (MESH:D018879,Disease) :: ['ventricular ectopic beats']
