UNASSIGNED: art may signal emotions independently of a biological or social carrier: it might therefore constitute a test case for defining brain mechanisms of generic emotion decoding and the impact of disease states on those mechanisms. This is potentially of particular relevance to diseases in the @entity747 ( @entity747 ) spectrum. These diseases are often led by emotional impairment despite retained or enhanced artistic interest in at least some @entity1 . However, the processing of emotion from art has not been studied systematically in @entity747 . Here we addressed this issue using a novel emotional valence matching task on abstract paintings in @entity1 representing major syndromes of @entity747 (behavioural variant frontotemporal @entity303 , n=11; sematic variant primary progressive @entity2026 (svPPA), n=7; nonfluent variant primary progressive @entity2026 (nfvPPA), n=6) relative to healthy older individuals (n=39). Performance on art emotion valence matching was compared between groups taking account of perceptual matching performance and assessed in relation to @entity2652 matching using customised control tasks. Neuroanatomical correlates of art emotion processing were assessed using voxel-based morphometry of @entity1 ' brain MR images. All @entity1 groups had a deficit of art emotion processing relative to healthy controls; there were no significant interactions between syndromic group and emotion modality. Poorer art emotion valence matching performance was associated with reduced grey matter volume in right lateral occopitotemporal cortex in proximity to regions previously implicated in the processing of dynamic visual signals. Our findings suggest that abstract art may be a useful model system for investigating mechanisms of generic emotion decoding and aesthetic processing in @entity179 .

Processing emotion from abstract art in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2652 :: ('MESH:D005148', 'Disease') :: ['facial emotion'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['aphasia'] @entity747 :: ('MESH:D057174', 'Disease') :: ['frontotemporal lobar degeneration', 'FTLD'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative diseases']
@entity747 :: (MESH:D057174,Disease) :: ['frontotemporal lobar degeneration']
