BACKGROUND: Self-expandable metallic stents (SEMSs) have provided satisfactory management of central @entity1224 . However, the long-term benefits and complications of this management modality in @entity1 with benign and @entity5 after SEMS placement are unclear. We performed this cohort study to analyze the outcomes of Ultraflex SEMSs in @entity1 with @entity66 . METHODS: Of 149 @entity1 , 72 with benign and 77 with malignant tracheobronchial disease received 211 SEMSs (benign, 116; malignant, 95) and were retrospectively reviewed in a tertiary hospital. RESULTS: The baseline characteristics of @entity1 who received SEMS implantation for benign conditions and those who underwent implantation for malignant conditions were significantly different. These characteristics included age (mean, 63.9 vs. 58; p < 0.01), gender (male, 62% vs. 90%; p < 0.0001), smoking (47% vs. 85%; p < 0.0001), forced expiratory volume in 1 second (mean, 0.9 vs. 1.47 L/s; p < 0.0001), follow-up days after SEMS implantation (median; 429 vs. 57; p < 0.0001), and use of covered SEMS (36.2% vs. 94.7%; p < 0.0001). Symptoms improved more after SEMS implantation in @entity1 with benign conditions than in those with malignant conditions (76.7% vs. 51.6%; p < 0.0001). The overall complication rate after SEMS implantation in @entity1 with benign conditions was higher than that in @entity1 with @entity5 (42.2% vs. 21.1%; p = 0.001). Successful management of SEMS migration, granulation tissue formation, and SEMS @entity174 occurred in 100%, 81.25%, and 85% of @entity1 , respectively. CONCLUSIONS: @entity1 who received SEMS implantation owing to benign conditions had worse lung function and were older than those who received SEMS for @entity5 . There was higher complication rate in @entity1 with benign conditions after a longer follow-up period owing to the nature of the underlying diseases.

An outcome analysis of self-expandable metallic stents in central XXXX : a cohort study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['tracheobronchial diseases'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant obstructing lesions', 'malignancy', 'malignancies'] @entity1224 :: ('MESH:D000402', 'Disease') :: ['airway obstruction']
@entity1224 :: (MESH:D000402,Disease) :: ['airway obstruction']
