BACKGROUND: Metastatic lesions in @entity263 beyond the bone have prognostic importance and affect clinical therapeutic decisions. Few data exist regarding the prevalence of soft-tissue @entity3 at the initial diagnosis of metastatic @entity263 (mCRPC). METHODS: This study analyzed 232 @entity1 with nonmetastatic (M0) @entity263 ( @entity263 ) who developed @entity3 detected by a bone scan or computed tomography (CT). All bone scans and CT scans within the 30 days before or after the mCRPC diagnosis were reviewed. The rate of soft-tissue @entity3 among those undergoing CT was determined. Then, predictors of soft-tissue @entity3 and visceral and lymph node @entity3 were identified. RESULTS: Compared with @entity1 undergoing CT (n   =   118), @entity1 undergoing only bone scans (n   =   114) were more likely to have received primary treatment (P   =   .048), were older (P   =   .013), and less recently developed @entity3 (P   =   .018). Among those undergoing CT, 52 (44%) had soft-tissue @entity3 , including 20 visceral @entity3 (17%) and 41 lymph node @entity3 (35%), whereas 30% had no bone involvement. In a univariable analysis, only @entity1486 ( @entity1486 ) predicted soft-tissue @entity3 (odds ratio [OR], 1.27; P   =   .047), and no statistically significant predictors of visceral @entity3 were found. A higher @entity1486 level was associated with an increased risk of lymph node @entity3 (OR, 1.38; P   =   .014), whereas receiving primary treatment was associated with decreased risk (OR, 0.36; P   =   .015). CONCLUSIONS: The data suggest that there is a relatively high rate of soft-tissue @entity3 (44%) among @entity263 @entity1 undergoing CT at the initial diagnosis of @entity3 , including some @entity1 with no bone involvement. Therefore, forgoing CT during a metastatic evaluation may lead to an underdiagnosis of soft-tissue @entity3 and an underdiagnosis of @entity3 in general. @entity5 2015.    2015 American @entity5 Society.

Is computed tomography a necessary part of a metastatic evaluation for XXXX ? Results from the Shared Equal Access Regional @entity5 Hospital Database.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity263 :: ('MESH:D011471', 'Disease') :: ['castration-resistant prostate cancer', 'CRPC', 'prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity1486 :: ('354', 'Gene') :: ['PSA', 'prostate-specific antigen']
@entity263 :: (MESH:D011471,Disease) :: ['castration-resistant prostate cancer']
