UNASSIGNED: Imaging devices such as the Heidelberg Retinal Tomograph ( @entity12447 ), scanning laser polarimetry ( @entity9999 ), and optical coherence tomography (OCT), play an important role in @entity726 diagnosis. A systematic search for evidence-based data was performed for prospective studies evaluating the diagnostic accuracy of @entity12447 , @entity9999 and OCT. The diagnostic odds ratio (DOR) was calculated. To compare the accuracy among instruments and parameters, a meta-analysis considering the hierarchical summary receiver operating characteristic (H-SROC) model was performed. The risk of bias was assessed using quality assessment of diagnostic accuracy studies (QUADAS-2). Studies in the context of screening programs were used for qualitative analysis. 86 manuscripts were included. The DOR values were 29.5 for OCT, 18.6 for @entity9999 , and 13.9 for HRT. The heterogeneity analysis demonstrated statistically a significant influence of degree of damage and ethnicity. Studies analyzing @entity1 with @entity726 showed poorer results. The risk of bias was high for @entity1 selection. Screening studies showed lower sensitivity values and similar specificity values when compared to those included in the meta-analysis. The classification capabilities of @entity9999 , HRT and OCT were high and similar across the 3 instruments. The highest estimated diagnostic odds ratio was obtained with OCT. Diagnostic accuracy could be overestimated in studies including pre-diagnosed groups of subjects.

Diagnostic Accuracy of Imaging XXXX : A Meta-Analysis.

@entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma', 'earlier glaucoma'] @entity9999 :: ('8266', 'Gene') :: ['GDx'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity12447 :: ('26508', 'Gene') :: ['HRT3']
@entity726 :: (MESH:D005901,Disease) :: ['Devices in Glaucoma']
