BACKGROUND: @entity146 ( @entity146 ) is a locally infiltrating soft-tissue @entity5 . In a population-based study in the Netherlands, we evaluated time trends for the incidence and treatment of @entity146 . METHODS: In PALGA: Dutch Pathology Registry, all @entity1 diagnosed between 1993 and 2013 as having extra-abdominal or abdominal wall aggressive @entity81 were identified and available pathology data of the @entity1 were evaluated. Epidemiological and treatment-related factors were analyzed with    (2)and regression analysis. RESULTS: During the study period, 1134 @entity1 were identified. The incidence increased from 2.10 to 5.36 per million @entity1 per year. Median age at the time of diagnosis increased annually by B 0.285 (P  =  0.001). Female gender prevailed and increased over time [annual odds ratio (OR) 1.022; P  =  0.058]. All anatomic localizations, but in particular truncal @entity5 , became more frequent. During the study period diagnostic histological biopsies were performed more often (annual OR 1.096; P  <  0.001). The proportion of @entity1 who underwent surgical treatment decreased (annual OR 0.928; P  <  0.001). When resection was preceded by biopsy, 49.8  % of the @entity1 had R0-resection versus 30.7  % in @entity1 without biopsy (P  <  0.001). CONCLUSIONS: In this population-based study, an increasing incidence of extra-abdominal and abdominal-wall aggressive @entity81 was observed. The workup of @entity1 improved and a trend towards a nonsurgical treatment policy was observed.

Time Trends in the Incidence and Treatment of Extra-Abdominal and XXXX : A Population-Based Study.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity81 :: ('MESH:D005350', 'Disease') :: ['fibromatosis'] @entity146 :: ('MESH:D001523', 'Disease') :: ['AF', 'Aggressive fibromatosis']
@entity146 :: (MESH:D001523,Disease) :: ['Abdominal Aggressive Fibromatosis']
