@entity426 are common in @entity1 with @entity191 . The pathophysiology of these disorders is not fully understood. Movement-related potentials reflect supplementary motor area activity associated with the preparation and execution of @entity717 . Our aim was to investigate movement-related potentials associated with gait disturbances in @entity1 with @entity191 , as reflected by gait @entity2845 and initiation difficulties, in order to better understand the role of the basal ganglia in the pathogenesis of these conditions. Movement-related potentials were back-averaged from electroencephalography recordings performed on 11 @entity1 with @entity191 with no gait initiation difficulties, 9 @entity1 with @entity191 who suffered from gait initiation difficulties, 12 young healthy adults, and 8 healthy older adults. @entity1 took 3 steps forward, stepping off a force plate. Trigger signals from the force plate and electromyographic activity of the tibialis anterior muscle were used to identify gait initiation time. @entity1 ' stride length was also measured using a 3-dimensional motion analysis system. Movement-related potentials showed significant group differences between the healthy young adults and the 2 @entity191 groups as well as the @entity191 group as a whole. No significant difference was found between the @entity1 with @entity191 and age-matched controls. A significant inverse relationship between movement-related potentials and stride length was found in @entity1 with @entity191 who did not experience gait initiation difficulties but not in those who did have this symptom. Gait-generated movement-related potentials appear to show electrical evidence of cortical disturbances correlated with stride length reduction in @entity1 with @entity191 without gait initiation difficulties.

Examination of central gait control mechanisms in XXXX using movement-related potentials.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'Participants', 'people'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease"] @entity2845 :: ('MESH:D018476', 'Disease') :: ['hypokinesia'] @entity426 :: ('MESH:D020233', 'Disease') :: ['Gait disorders'] @entity717 :: ('MESH:D009069', 'Disease') :: ['voluntary movement']
@entity191 :: (MESH:D010300,Disease) :: ['Parkinson's disease']
