OBJECTIVE: To identify @entity74 associated with @entity854 ; type and frequency of various @entity854 associated with selected genetic and @entity74 ; and devise a suitable classification for @entity854 . METHODS: Pediatric cases referred with @entity1032 , @entity600 and suspected genetic and @entity209 were enrolled prospectively. Relevant clinical details (including an ophthalmologic examination) and investigations were recorded. RESULT: Of the 1308 @entity1 enrolled, 679 (51.9%) had @entity854 . 458 cases (67.45%) out of these 679 had @entity1032 and 20 (2.94%) had neuroregression. Environmental (12.22%) and @entity2008 (10.9%) were the largest etiological groups. Down syndrome was the commonest of the @entity2008 and mongoloid slant and epicanthic folds were its commonest ophthalmologic features. Mucopolysaccharidoses (21.4%), @entity2360 (19.64%), @entity16392 (16.07%) and lipid storage disorders (14.29%) were the most common @entity2246 associated with @entity854 . Of the 39 cases with @entity74 , @entity74 (56.41%) were the commonest associated with @entity735 . A simple anatomical classification has been devised for various @entity854 encountered (wherein, positional and @entity20428 were the commonest). CONCLUSION: Up to 50% of cases referred to the genetic services have @entity854 . Conditions including @entity2008 , @entity209 , @entity74 and environmental factors are associated with @entity735 . Anatomically, positional and @entity20428 are the commonest.

Congenital and XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['mental retardation'] @entity600 :: ('MESH:D000014', 'Disease') :: ['congenital malformations'] @entity735 :: ('MESH:D005124', 'Disease') :: ['ocular abnormalities'] @entity854 :: ('MESH:D018376', 'Disease') :: ['ophthalmologic abnormalities'] @entity16392 :: ('MESH:D016115', 'Disease') :: ['oculocutaneous albinism'] @entity2360 :: ('MESH:D006527', 'Disease') :: ['Wilson disease'] @entity74 :: ('MESH:D030342', 'Disease') :: ['inherited disorders', 'autosomal dominant disorders', 'genetic disorders', 'Mendelian syndromes', 'Mendelian inheritance of disorders'] @entity20428 :: ('MESH:D000291', 'Disease') :: ['adnexal abnormalities'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic disorders'] @entity2008 :: ('MESH:D002869', 'Disease') :: ['chromosomal abnormalities', 'chromosomal anomalies'] @entity2246 :: ('MESH:D008661', 'Disease') :: ['inborn errors of metabolism']
@entity74 :: (MESH:D030342,Disease) :: ['inherited ophthalmologic abnormalities']
