@entity11730 ) has been developed as a new oral anticancer drug based on the biological modulation of @entity1487 . We treated a @entity1 with highly advanced @entity356 with a new combination chemotherapy of @entity11730 and low-dose @entity900 . Remarkable @entity5 reduction was observed after two cycles of this therapy in the @entity5 and metastatic lymph nodes, and the @entity843 disappeared. This was concluded to be a partial response. The only adverse effect was skin pigmentation of the fingers (grade 1), leading to early timing of operation after chemotherapy. The @entity356 showed evident invasion to the serosa. Lymph nodes around the stomach were swollen. Peritoneal dissemination was also recognized in the omentum and mesocolon. Total gastrectomy with regional lymph node dissection was performed. @entity5 were all resected. Histological examination showed that no @entity5 cells were detected in the gastric @entity75 , metastatic lymph nodes or disseminated @entity3906 , suggesting pathological complete remission. It was suggested that this regimen could be a potent combined therapy for the treatment of @entity1 with highly advanced @entity356 , and it could be useful as neoadjuvant chemotherapy. Further studies are necessary to evaluate the efficacy of this therapy.

Complete response of highly advanced @entity356 with peritoneal dissemination after new combined chemotherapy of @entity11730 and low-dose XXXX : report of a case.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity11730 :: ('5707', 'Gene') :: ['TS-1(S-1', 'S-1'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Disseminated tumors', 'primary tumor'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesion'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity900 :: ('MESH:D002945', 'Chemical') :: ['cisplatin'] @entity3906 :: ('MESH:D010534', 'Disease') :: ['peritoneal tumors'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric tumor', 'gastric carcinoma'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-fluorouracil']
@entity900 :: (MESH:D002945,Chemical) :: ['cisplatin']
