A cross-sectional study of 155 @entity1 who underwent genetic testing for @entity4309 ( @entity4309 ) examined long-term psychosocial and behavioral outcomes. @entity1 completed standardized measures of perceived risk, psychosocial functioning, knowledge, and a questionnaire of screening activities. @entity1 were on average 47.3   years and had undergone testing a mean of 5.5   years prior. Eighty four (54%) tested positive for a @entity4309 mutation and 71 (46%) negative. For unaffected carriers, perceived lifetime risk of @entity14 was 68%, and surprisingly, 40% among those testing negative. Most individuals demonstrated normative levels of psychosocial functioning. However, 25% of those testing negative had moderate @entity308 , as measured by the Center for Epidemiologic Studies for @entity308 Scale, and 31% elevated state @entity148 on the State-Trait @entity148 Inventory. Being female and a stronger escape  -  avoidant coping style were predictive of @entity308 . For state @entity148 , similar patterns were observed. Quality of life and social support were significantly associated with lower @entity148 . Carriers maintained higher knowledge compared to those testing negative, and were more engaged in screening. In summary, most individuals adapt to genetic test results over the long term and continue to engage in screening. A subgroup, including some non-carriers, may require added psychosocial support.

Long-term psychosocial and behavioral adjustment in individuals receiving genetic test results in XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'Participants'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression', 'depressive symptoms'] @entity4309 :: ('MESH:D003123', 'Disease') :: ['Lynch syndrome', 'LS'] @entity148 :: ('MESH:D001008', 'Disease') :: ['Anxiety', 'anxiety'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer']
@entity4309 :: (MESH:D003123,Disease) :: ['Lynch syndrome']
