Ten percent of @entity1 are left handed, but a higher frequency has been associated with certain craniofacial @entity600 , such as @entity3384 and @entity91 . The purpose of this study was to determine the frequency of left-handedness in @entity1 with @entity4802 ( @entity4802 ). @entity1 with @entity4802 were identified in our craniofacial database. Normal controls were recruited by local pediatricians. Data gathered included age, sex, and handedness (determined by writing and/or drawing); the orbit, mandible, ear, nerve, and soft tissue (OMENS)-plus score and side of involvement were tabulated for @entity1 with @entity4802 . Hand preference was compared between the groups using chi analysis; possible correlations were analyzed between handedness and age, sex, the OMENS score, extracraniofacial findings, and side of involvement. One hundred seventy-eight @entity1 with @entity4802 were identified; 92 (51%) were excluded. Of the 86 included, 48% were @entity1 (n = 47) and the mean age at inquiry was 13.5 years. Predominant side of involvement was right in 49% (n = 42) and left in 38% (n = 33). Eleven @entity1 (13%) had severe involvement of both sides. Expanded-spectrum @entity4802 was documented in 41% of @entity1 . Ninety-six @entity1 were in the control group; 44% were @entity1 (n = 42), and the mean age was 10 years. The difference in age between the groups was significant (P < 0.05), but sex differences were not. @entity1 with @entity4802 were more likely to be left handed for writing compared with the control group (26% vs. 11%; P < 0.05). The frequency was higher, 36%, in those with bilateral involvement (P > 0.05). There was no correlation with predominant side or OMENS score. This study confirms that this disorder affects cerebral lateralization.

Increased prevalence of left-handedness in XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'boys', 'people'] @entity4802 :: ('MESH:D006053', 'Disease') :: ['HFM', 'hemifacial microsomia'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity91 :: ('MESH:D003398', 'Disease') :: ['unilateral coronal synostosis'] @entity3384 :: ('MESH:D002971', 'Disease') :: ['cleft lip']
@entity4802 :: (MESH:D006053,Disease) :: ['hemifacial microsomia']
