Compound @entity535 solution (CAAS) is a large class of solution of @entity1522 ' mixture and was widely used in China. Its extensive nutritional treatment was accompanied by a substantial incidence of adverse reactions, especially life-threatening anaphylaxis. However, the adverse reactions were reported in isolated case reports only, and the reasons behind this needed further investigation. The Chinese language papers were searched from China National Knowledge Infrastructure and Wanfang database published in China from 1985 to 2010. The search terms "anaphylactic", "anaphylaxis", " @entity56 ", " @entity566 ", "shock", and "adverse reaction" combined with the term " @entity535 " were used. Totally 71 episodes of @entity2021 and seven @entity204 in 38 articles were analyzed. @entity5837 and cool extremities were the most common clinical manifestations. Almost all @entity1 suffered from significant @entity551 . The vast majority of @entity1 were not found to be @entity56 to certain substances. CAAS was inappropriately administrated in more than one-third of @entity1 . The life-threatening anaphylaxis was prominently prevalent in pregnant @entity1 , the elderly and @entity1 with @entity56 such as @entity565 , and @entity1 without medicinal indication. Innovation of processing technique and establishment of more strict supervision system are an urgent need for CAAS to control its production quality and thus improve its safety in China.

@entity2021 and lethal anaphylaxis caused by compound XXXX solution, a nutritional treatment widely used in China.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity1522 :: ('CHEBI:33709', 'Chemical') :: ['amino acids'] @entity535 :: ('CHEBI:33704', 'Chemical') :: ['amino acid'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergy'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity5837 :: ('MESH:D056586', 'Disease') :: ['Chest distress'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity56 :: ('MESH:D004342', 'Disease') :: ['hypersensitivity', 'allergic'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths'] @entity2021 :: ('MESH:D000707', 'Disease') :: ['anaphylactic shock']
@entity535 :: (CHEBI:33704,Chemical) :: ['amino acid']
