OBJECTIVE: To assess the influence of hyperoxygenation on surgical @entity281 by using the most homogeneous study population. DESIGN: A randomized, prospective, controlled trial. SETTING: Department of surgery in a government hospital. @entity1 : A total of 210 @entity1 who underwent open surgery for @entity697 . In the study group, @entity1 received 80% @entity26 during anesthesia, followed by high-flow @entity26 for 2 hours in the recovery room. The control group received 30% @entity26 , as usual. INTERVENTION: Open appendectomy via incision in the right lower quadrant of the abdomen. MAIN OUTCOME MEASURES: @entity281 , mainly assessed by the ASEPSIS (additional treatment, serous discharge, erythema, purulent discharge, separation of deep tissues, isolation of bacteria, and stay in hospital prolonged >14 days) system score. RESULTS: Surgical site infections were recorded in 6 of 107 @entity1 (5.6%) in the study group vs 14 of 103 @entity1 (13.6%) in the control group (P = .04). Significant differences in the ASEPSIS score were also found. The mean hospital stay was longer in the control group (2.92 days) compared with the study group (2.51 days) (P = .01). CONCLUSION: The use of supplemental @entity26 is advantageous in operations for @entity697 by reducing surgical @entity281 rate and hospital stay. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01002365.

Perioperative hyperoxygenation and wound @entity281 following surgery for XXXX : a randomized, prospective, controlled trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Surgical site infection', 'site infection'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute appendicitis']
@entity697 :: (MESH:D000208,Disease) :: ['acute appendicitis']
