We performed a prospective study in order: 1) to determine whether a correlation could be found between serum @entity11153 ( @entity11153 ) levels and clinical and functional status in perennial @entity748 during a 5 month prospective study; and 2) to evaluate the relationship between allergic exposure and @entity11153 levels in periodic @entity748 . Two groups of @entity748 @entity1 were selected: a group of acutely ill perennial @entity748 and a group of periodic @entity748 . The acutely ill perennial @entity748 (n=22, mean age=39.4 yrs) were included on the basis of hospitalization for acute @entity565 . At the end of the hospitalization, there was a 5 month follow-up of clinical, functional and medication scores, as well as eosinophil counts and @entity11153 levels. The periodic @entity748 group was composed of @entity748 sensitized to birch and tree pollens (n=10, mean age=33.8 yrs). The same measurement were performed on this group, before, during and after the pollen season. Under corticosteroid treatment in the acutely ill @entity1 , there was a significant decrease in serum @entity11153 levels between the first day of hospitalization and the day of discharge (mean: 23.2 microg x L(-1) and 9.5 microg x L(-1), respectively; p=0.006). No correlation was found between the clinical status, functional status and serum @entity11153 levels during the 5 month follow-up. A significant increase in @entity11153 levels was found in periodic @entity748 during the pollen season. Our results suggest that serum @entity11153 is a useful marker of allergen exposure and of acute @entity565 treatment. This could be of importance in the prevention and follow-up of @entity56 ; the value of serum @entity11153 measurements in the day-to-day management of adult @entity748 needs to be further clarified.

Serum @entity11153 measurements in the management of perennial and periodic XXXX : a prospective study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity748 :: ('MESH:D013224', 'Disease') :: ['asthmatic', 'asthmatics'] @entity11153 :: ('6037', 'Gene') :: ['eosinophil cationic protein', 'ECP'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity56 :: ('MESH:D004342', 'Disease') :: ['allergic asthma']
@entity565 :: (MESH:D001249,Disease) :: ['asthma']
