OBJECTIVE: To analyze the incidence and risk factors for clinically apparent and occult lymph node @entity3 in @entity1 with major @entity5 . DESIGN: Cohort of @entity1 with a median follow-up of 46 months (range, 1-174 months). SETTING: University-based referral center. @entity1 : A total of 160 consecutive @entity1 with complete clinical and pathologic data. INTERVENTION: Neck dissection was performed in all cases. @entity1 were treated with surgery alone (55%); surgery and radiation therapy (43%); or a combination of surgery, radiation, and chemotherapy (2%). MAIN OUTCOME MEASURE: Incidence of apparent and occult lymph node @entity3 . Univariate and multivariate analyses were used to evaluate the significance of clinical and pathologic data. RESULTS: Histologically confirmed positive neck was found in 53% of all cases. Histologic diagnosis was significantly related to the incidence of @entity1600 : 89% (16/18) for @entity189 . However, so-called low-risk @entity5 had incidence rates of 22% to 47%. Twenty-one @entity1 (13%) presented with clinically apparent cervical @entity1600 . Of the 139 @entity1 with clinical N0 neck, 45% had occult neck @entity3 . Neck @entity3 was found in 29% (10/34) of T1, 54% (38/70) of T2, 65% (20/31) of T3, and 54% (16/25) of T4 @entity5 . Assessment of survival according to nodal status revealed significant correlations for overall (P<.001) and disease-free survival (P<.001). CONCLUSIONS: We found a high incidence of @entity1600 from major @entity5 . Neck dissections should be considered as an integral part of the surgical approach in @entity1 with major @entity5 , especially if no postoperative radiation therapy is planned.

High incidence of @entity1600 in major XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['salivary gland cancer', 'salivary gland cancers', 'tumors'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['lymph node metastasis'] @entity189 :: ('MESH:D002277', 'Disease') :: ['undifferentiated carcinomas'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases']
@entity5 :: (MESH:D009369,Disease) :: ['salivary gland cancer']
