OBJECTIVES: Because of the high rate of @entity41 after transurethral resection (TUR) and possible pT0 finding on postoperative vesical specimens after initial TUR, we studied the data achieved after a second TUR (reTUR) in pT2N0M0 @entity150 who underwent adjuvant radiotherapy. @entity1 AND METHODS: Between February 1996 and January 2002, we studied 169 cases (91 males and 78 females) with pT2 @entity150 , which underwent reTUR within four to six weeks from the initial resection. @entity5 location was documented at both procedures on a designed map of the bladder. For the pT2G3 series (40 cases), we practiced laparoscopic lymphadenectomy concomitant with reTUR. For pT0N0 @entity5 (62 cases), we applied adjuvant external beam radiotherapy (66Gy). For @entity41 after reTUR and N+ cases (107 @entity1 ), we applied radical cystectomy. RESULTS: We found 95 cases (56.2%) with @entity41 at reTUR: 4 noninvasive @entity5 (4.2%), 70 with the same stage (73.7%) and 21 upstaged to @entity1803 (22.1%). Radical cystectomy was performed in all these cases. For the 74 pT0 cases (43.8%) we applied laparoscopic lymphadenectomy in high-risk @entity5 (40 G2/3 cases) concomitant with reTUR. So, we found 28 N0 cases (70%) and 12 N+ cases (30%), radical cystectomy being applied in this last series. Finally, for a total of 62 pT0N0 cases under external beam radiotherapy (66Gy) we found 7 cases (11.3%) with local recurrences (3 cases with concomitant lymph node involvement) and 2 cases (3.2%) with @entity262 without local evidence. The disease-free survival was 85.4%. The mean follow-up period was 41 months (range 10-70 months). CONCLUSIONS: According to our experience the routine reTUR could detect an important rate of pT0 stage after initial TUR in pT2 @entity150 . So, reTUR could better select @entity1 for bladder preservation (adjuvant radiotherapy being used), in addition to laparoscopic lymph nodes evaluation for high-risk @entity5 .

Second transurethral resection and adjuvant radiotherapy in conservative treatment of pT2N0M0 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity1803 :: ('7694', 'Gene') :: ['pT3'] @entity41 :: ('MESH:D018365', 'Disease') :: ['residual tumors', 'residual tumor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Tumor', 'tumors'] @entity262 :: ('MESH:D034721', 'Disease') :: ['systemic disease'] @entity150 :: ('MESH:D001749', 'Disease') :: ['bladder tumors']
@entity150 :: (MESH:D001749,Disease) :: ['bladder tumors']
