BACKGROUND: Ultrasound-guided percutaneous @entity1068 injection ( @entity8681 ) and percutaneous @entity1543 injection (PAI) are effective in the treatment of @entity157 ( @entity157 ). We conducted a prospective study to compare the therapeutic efficacy of both these methods. METHODS: Sixty-three @entity1 were treated by PAI using 50% @entity1543 and 62 by @entity8681 using pure @entity1068 . There were no significant baseline differences in age, sex, @entity1 -Pugh class, @entity5 size and number, or other clinico-biochemical parameters between the two groups. RESULTS: During a follow-up period of 24 +/- 9 (range 6-38) months, 19 (30%) of the PAI group and 21 (34%) of the @entity8681 group died (P = 0.704). The 1- and 3-year survival rates were 84% and 51% for the PAI group and 81% and 46% for the @entity8681 group (P = 0.651). The corresponding @entity5 recurrence rates were 51% and 74% for the PAI group, and 54% and 64% for the @entity8681 group (P = 0.787). The treatment sessions were 3.9 +/- 1.6 and 6.2 +/- 2.3 for the PAI and @entity8681 groups, respectively, in each treatment cycle (P = 0.008). A multivariate analysis using the Cox regression model revealed that ascites (relative risk (RR) 3.1, 95% confidence interval (CI) 1.5-6.3, P = 0.002), large (>3 cm) or multinodular HCCs (RR 2.4, 95% CI 1.1-5.4, P = 0.04), and development of @entity5 recurrence (RR 7.0, 95% CI 3.1-16.0, P < 0.001) were independent, poor prognostic factors in both groups. CONCLUSIONS: PAI and @entity8681 are equally effective in the treatment of @entity157 . PAI has the advantage of fewer treatment sessions in each treatment course. Careful pretreatment @entity1 selection may improve survival.

Comparison of percutaneous @entity1543 injection and percutaneous @entity1068 injection for @entity157 in cirrhotic XXXX : a prospective study.

@entity1 :: ('9606', 'Species') :: ['Child', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity8681 :: ('CHEBI:53231', 'Chemical') :: ['PEI'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol'] @entity1543 :: ('MESH:D019342', 'Chemical') :: ['acetic acid']
@entity1 :: (9606,Species) :: ['patients']
