UNASSIGNED: The association between @entity285 consumption and @entity355 ( @entity355 ) remained uncertain and controversial in the previous studies. We performed a meta-analysis of observational studies to clarify the association.We searched PubMed, Web of Science, and Embase for studies on @entity285 consumption and risk of @entity355 published before February 2015. A total of 20 studies reporting the association between @entity285 consumption and the risk of @entity355 were identified. Subgroup analyses, meta-regression analyses, sensitivity analyses, and publication bias tests were also performed. Several results from individual studies were pooled using a dose-response meta-analysis.A total of 20 studies involving 45,181 @entity1 and 4432 @entity1 of @entity355 were included in the meta-analysis. No association was found between @entity285 consumption and @entity355 (relative risk [RR]=1.10, 95% confidence interval [CI] 0.96-1.27, I=48.60%) in our study. In subgroup analysis, @entity285 consumption was associated with an increased risk of @entity355 in @entity1 (RR=1.35, 95% CI 1.13-1.61, I=0.00%) and Asian population (RR=1.60, 95% CI 1.03-2.49, I=60.60%). In beverage-specific consumption analysis, liquor was associated with an increased risk of @entity355 (RR=1.16, 95% CI 1.02-1.32, I=0.00%). Multivariate meta-regression analysis suggested that geographic area, and adjusted age, sex, body mass index, and smoke, might explain 70.75% of the heterogeneity between the studies. We also found the inverse association (RR=0.84, 95% CI 0.72-0.98, I=0.00%) between @entity285 consumption and @entity355 among subjects when compared with population controls.Overall, there was no significant association between @entity285 consumption and @entity355 . @entity285 consumption may be a risk factor of @entity355 in @entity1 and Asian population, and liquor consumption may also increase the risk of @entity355 . Significant inverse association was observed between @entity285 consumption and @entity355 , for comparisons with population controls.

Association Between XXXX Consumption and the Risk of Barrett's Esophagus: A Meta-Analysis of Observational Studies.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'men'] @entity285 :: ('D000431', 'Chemical') :: ['alcohol', 'Alcohol'] @entity355 :: ('MESH:D001471', 'Disease') :: ['BE', "Barrett's esophagus"]
@entity285 :: (D000431,Chemical) :: ['Alcohol']
