BACKGROUND/AIMS: To investigate the recurrence patterns and interval from initial surgery in @entity1 with curatively resected @entity14 followed for a minimum of 10 years. METHODOLOGY: We retrospectively reviewed 418 @entity1 who had undergone curative resection for @entity694 (n = 246) or @entity5 (n = 169). Follow-up periods ranged from 10 to 23 years. Main outcome measures were interval until recurrence, site of first recurrence, and influence of adjuvant chemotherapy. RESULTS: 26 (6%) had been lost to follow-up by 10 years and 143 (34%) had died. The most common site of recurrence was liver in @entity694 and locoregional in @entity5 . The cumulative recurrence rate in @entity694 was 100% at 4 years. In @entity5 , it was 89% at 5 years, 98% at 7 years and 100% at 10 years. The interval until recurrence was longer in @entity5 (26.0 +/- 24.2 months) than in @entity694 (17.1 +/- 11.0 months) (p = 0.03). It was also longer in @entity1 receiving than in those not receiving adjuvant chemotherapy (p < 0.01). The interval until lung metastasis was longer than that until liver metastasis in @entity694 (p = 0.04), and longer than that until locoregional recurrence in @entity5 (p = 0.03). The interval until recurrence in the @entity694 was shorter for stage III than for stage II (p = 0.02). CONCLUSIONS: Surveillance for recurrences, particularly for relapses in the liver and lung, should be performed for at least 4 years in @entity694 @entity1 . @entity1 with @entity5 should be followed for a longer period than those with @entity694 , focusing on locoregional, liver and lung recurrence. It is particularly noteworthy that adjuvant chemotherapy may prolong the interval until recurrence and the interval until lung metastasis is relatively longer.

Recurrence patterns after curative resection of @entity14 in XXXX followed for a minimum of ten years.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['rectal cancer'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer']
@entity1 :: (9606,Species) :: ['patients']
