We report on a 58-year-old male diagnosed as having primary @entity4018 with @entity882 , who died of fatal @entity326 and @entity5925 after platelet concentrates (PCs) transfusion. The initial diagnosis of primary @entity4018 was established by @entity381 , leukoerythroblastosis and @entity4018 . PCs were transfused because of @entity882 with marked @entity548 tendency. Soon after the PCs transfusion in March 2000, he had attacks of @entity662 , back @entity158 and @entity925 , then went into shock and died of unknown causes. PCs were suspected as being the cause of @entity204 , because @entity328 was found in the culture of PCs in the WBC-reduction in-line filter and fresh frozen plasma from the same donor preserved in the Japan Red Cross Center. @entity5925 , neutrophil infiltration and phagocytosed bacteria were found from the autopsy materials, which were identified by DNA analysis as the same species found in the PCs. PCs are kept at room temperature because platelet function is lost in the cold. When PCs are contaminated with bacteria, marked multiplication induces fatal @entity2259 . This is a rare report in Japan of fatal @entity326 caused by PCs with bacterial contamination. We must pay strict attention to @entity1503 .

[Fatal @entity326 and @entity5925 following transfusion of platelet concentrates contaminated with XXXX ].

@entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity882 :: ('MESH:D013921', 'Disease') :: ['thrombocytopenia'] @entity326 :: ('MESH:D012772', 'Disease') :: ['septic shock'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['bacterial contamination in blood components'] @entity5925 :: ('MESH:D012206', 'Disease') :: ['Rhabdomyolysis', 'rhabdomyolysis'] @entity4018 :: ('MESH:D055728', 'Disease') :: ['bone marrow fibrosis', 'myelofibrosis'] @entity381 :: ('MESH:D013163', 'Disease') :: ['splenomegaly'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity925 :: ('MESH:D063806', 'Disease') :: ['myalgia'] @entity328 :: ('1313', 'Species') :: ['Streptococcus pneumoniae'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity2259 :: ('MESH:D016470', 'Disease') :: ['bacteremia']
@entity328 :: (1313,Species) :: ['Streptococcus pneumoniae']
