OBJECTIVES: The primary @entity6732 (PTENs) are uncommon @entity5 with a broad spectrum of both biological and morphological features. The aim of this study is to analyse the prognostic factors that influence survival. METHODS: Forty-four @entity1 with a complete follow-up were analysed. Nine @entity1 (20.5%) were asymptomatic, the most common symptoms in the rest being @entity1737 and dyspnoea. All the @entity1 underwent surgery, 30 cases (68.2%) receiving total thymectomy and the rest a partial resection or biopsy. Marino-M  ller's histological classification showed the mixed type to be the most common (52.3%). Clinical staging was done according to the Masaoka classification, which gave the most common stage as stage III (34.1%). RESULTS: Twelve @entity1 died during a mean follow-up of 8.2 +/- 3.5 years. The accumulated survival rate was 77% at 5 years and 60% at 10 years. Analysis of the survival curves shows significant differences (P<0.05) when considering surgical technique, clinical staging and histological subtype. The multivariate analysis shows the only parameters with prognostic significance in PTENs to be clinical staging and histological type (P<0.001). CONCLUSIONS: The most important prognostic factors in PTENs are Masaoka's clinical staging and Marino-M  ller's histological subtype.

Prognostic factors in XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumours'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity6732 :: ('MESH:D013953', 'Disease') :: ['thymic epithelial neoplasms'] @entity1737 :: ('MESH:D009157', 'Disease') :: ['myasthenia gravis']
@entity6732 :: (MESH:D013953,Disease) :: ['thymic epithelial neoplasms']
