OBJECTIVES: By whole-body MRI (WBMRI), we aimed to examine the frequency and distribution of inflammatory and structural lesions in PsA @entity1 , @entity11028 @entity1 and healthy subjects (HSs), to introduce global WBMRI @entity32 /damage scores, and to assess WBMRI's reproducibility and correlation with conventional MRI (convMRI). METHODS: WBMRI (3.0-T) of @entity1 with peripheral PsA (n = 18) or axial @entity11028 (n = 18) and of @entity8682 (n = 12) was examined for proportion of evaluable features (readability) and the presence and pattern of lesions in axial and @entity1897 . Furthermore, global WBMRI scores of @entity32 and structural damage were constructed, and WBMRI findings were compared with clinical measures and convMRI ( @entity11028 / @entity8682 : spine and SI joints; PsA/ @entity8682 : hand). RESULTS: The readability (92-100%) and reproducibility (intrareader intraclass correlation coefficient: 0.62-1.0) were high in spine/SI joint, but lower in the distal @entity1897 . Wrists, shoulders, knees, ankles and @entity12437 joints were most commonly involved, with frequency of @entity603 > @entity236 ( @entity236 ) > erosion. WBMRI global @entity236 scores of peripheral and axial joints were higher in PsA {median 7 [interquartile range (IQR) 3-15]} and @entity11028 [8 (IQR 2-14)] than in HSs [2.5 (IQR 1-4.5)], both P < 0.05. WBMRI global structural damage scores (erosion, fat infiltration and @entity3947 ) were higher in @entity11028 [7 (IQR 3-12)] than HSs [1.5 (IQR 0-4.5)], P = 0.012. Correlations between WBMRI and convMRI spine and SI joint scores were    = 0.20-0.78. CONCLUSION: WBMRI allows simultaneous assessment of peripheral and axial joints in PsA and @entity11028 , and the distribution of inflammatory and structural lesions and global scores can be determined. The study strongly encourages further development and longitudinal testing of WBMRI techniques and assessment methods in PsA and @entity11028 .

Head-to-toe whole-body MRI in psoriatic arthritis, axial spondyloarthritis and healthy subjects: first steps towards global XXXX and damage scores of peripheral and axial joints.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity12437 :: ('MESH:D000012', 'Disease') :: ['MTP'] @entity11028 :: ('729238', 'Gene') :: ['SpA'] @entity3947 :: ('MESH:D000844', 'Disease') :: ['ankylosis'] @entity603 :: ('MESH:D013585', 'Disease') :: ['synovitis'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral joints'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow oedema', 'BMO'] @entity8682 :: ('MESH:C567159', 'Disease') :: ['HS']
@entity32 :: (MESH:D007249,Disease) :: ['inflammation']
