BACKGROUND: Little is known regarding the incidence of main pancreatic duct disruption in @entity1 suffering from @entity656 and whether the occurrence of this disruption may contribute to the decision to intervene surgically. The aim of this prospective study was to assess these findings in a group of @entity1 with @entity656 . @entity1 AND METHODS: Seventy-five consecutive @entity1 with @entity39 acute @entity788 and suspected biliary etiology underwent endoscopic retrograde cholangiopancreatography within the first week upon admission. @entity788 (common bile duct stones or endoscopic features probative for recent transpapillary stone migration in @entity1 with @entity5990 ) was confirmed in 70 @entity1 . Imaging not only of the biliary tract but also of the pancreatic ducts was pursued. Fifty-one @entity1 (72.8%) were conservatively treated, 19 (27.1%) underwent surgery: indication for surgery was infection of @entity39 in 15 cases, @entity9007 in 3 cases, and @entity292 in 1 case. RESULTS: Satisfactory visualization of the main pancreatic duct was achieved in 59 cases (84.3%). Disruption of the main pancreatic duct was observed in 18 cases (30.5%), ie, 5 of the 17 @entity1 who underwent surgery and 13 of the 42 @entity1 who were nonoperatively managed (NS). CONCLUSIONS: Our results suggest that the loss of integrity of the main pancreatic duct, as verified with endoscopic pancreatography, constitutes quite a frequent event in @entity656 , and it should not be considered as an absolute indication for surgery in @entity1 with sterile @entity39 . Most of these @entity1 can be safely managed without surgery.

The incidence of main pancreatic duct disruption in severe XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity788 :: ('MESH:D010190', 'Disease') :: ['Biliary pancreatitis', 'pancreatitis'] @entity656 :: ('MESH:D019283', 'Disease') :: ['acute necrotizing biliary pancreatitis', 'acute biliary pancreatitis', 'acute necrotizing pancreatitis'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis', 'necrotizing'] @entity5990 :: ('MESH:D042882', 'Disease') :: ['gallstones'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula'] @entity9007 :: ('MESH:D010192', 'Disease') :: ['pseudocysts']
@entity788 :: (MESH:D010190,Disease) :: ['biliary pancreatitis']
