OBJECTIVES: In this study, the efficacy of a miswak extract-containing toothpaste (Salvadora persica) on @entity32 was compared with that of a herbal and a conventional toothpaste. METHODS: Non-smoking outpatients with sulcus bleeding index (SBI) >= 25% and with periodontal pocket depths  <=3 mm were randomly selected and divided into three groups: M-group, miswak extract-containing toothpaste; P-group, herbal toothpaste; and C-group, conventional toothpaste. After instructing the @entity1 to brush their teeth twice a day for 3 weeks with the assigned toothpaste using a flat-trimmed manual toothbrush, a thorough oral examination was performed by a calibrated examiner (EH). The primary outcome was the SBI after 21 days. Furthermore, the amount of plaque was measured by approximal plaque index (API). RESULTS: Sixty-six @entity1 with a mean age of 57.8    10.2 years were recruited and enrolled. After 3 weeks of brushing, all three @entity1 groups showed a significant reduction in SBI. The P-group (SBI reduction: 17.1%    9.1) and the M-group (14.5%    8.1) showed the strongest effect followed by the C-group (9.4%    7.8). All three groups showed a significant reduction in API without significant differences between the groups. CONCLUSIONS: The use of each of the three tested toothpastes caused a significant @entity32 and amount of plaque. The miswak extract-containing toothpaste showed a similar effect as the herbal toothpaste and can be safely used for domestic oral hygiene in @entity1 with @entity2522 .

Effectiveness of a miswak extract-containing toothpaste on XXXX : a randomized clinical trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['gingival inflammation', 'reduction in gingival inflammation'] @entity2522 :: ('MESH:D005891', 'Disease') :: ['gingivitis']
@entity32 :: (MESH:D007249,Disease) :: ['gingival inflammation']
