OBJECTIVE: Tick-borne @entity198 (TBE) was detected in the Koprivnica-Krizevci County 50 years ago. To date, it has retained the leading position among @entity6220 (CNS), with an average morbidity of 20 @entity1 per year. In 88% of @entity1 , the @entity281 manifested with signs of @entity693 or @entity5422 ( @entity5422 ). Monophasic course was recorded in only 12% of @entity1 of older age, during which the first initial stage remained inapparent, and the disease manifested only with @entity5422 stage. An @entity778 with @entity221 , @entity10 and other general symptoms of @entity281 is presented. The initial stage of the disease, without subsequent CNS involvement, is rarely described. PURPOSE OF WORK: To determine the frequency and present epidemiological, clinical and laboratory characteristics as well as diagnostic procedures in @entity1 suffering from abortive type of TBE. @entity1 AND METHODS: A prospective study was conducted in the period from 1997-2002, and included @entity1 with possible @entity7545 , examined at the Infectious Disease Department of the Koprivnica General Hospital. According to the set criteria, the study included @entity1 of all age groups, sex and occupation, @entity1 with @entity66 (T 38 degrees C) that developed within 6 weeks from the tick bite, @entity1 who showed no signs of @entity5422 on their first examination, and @entity1 in whom serologic analysis revealed @entity778 . On admission to the hospital, detailed epidemiological and history data were collected, and clinical examination and laboratory testing were performed. ELISA test was used to detect specific IgM and IgG antibodies. At the same time all serum samples were tested for other @entity7545 , including @entity3001 and @entity1 monocyte and granulocyte @entity12431 . Oral consent was obtained from all @entity1 enrolled in the study. RESULTS: A total of 127 @entity1 met the study criteria. Specific antibodies to TBE virus were detected in 49 (38.5%) @entity1 . After the latency period, 43 (87.7%) @entity1 developed the second stage of @entity66 . An @entity281 with TBE virus, without subsequent CNS involvement, was recorded in 6 (12.2%) @entity1 . The diagnosis was confirmed in the first initial stage in 12% of @entity1 and during the second @entity5422 stage in the remaining 37 (75.5%) @entity1 . Active immunization against TBE was not conducted in any @entity1 . CONCLUSION: We report on the first @entity1 diagnosed with an @entity778 in the Koprivnica-Krizevci County. The frequency of and new knowledge about this type of disease were assessed in the study.

[An abortive type of tick-borne XXXX ].

@entity1 :: ('9606', 'Species') :: ['human', 'patient', 'patients', 'PATIENTS'] @entity778 :: ('MESH:D015658', 'Disease') :: ['abortive type of TBE virus infection', 'recent infection with TBE virus'] @entity6220 :: ('MESH:D020279', 'Disease') :: ['inflammatory diseases of the central nervous system'] @entity3001 :: ('MESH:D008193', 'Disease') :: ['Lyme disease'] @entity198 :: ('MESH:D004660', 'Disease') :: ['encephalitis'] @entity66 :: ('MESH:D004194', 'Disease') :: ['febrile disease', 'ME disease'] @entity12431 :: ('MESH:D016873', 'Disease') :: ['ehrlichiosis'] @entity5422 :: ('MESH:D008590', 'Disease') :: ['biphasic meningoencephalitis', 'ME'] @entity693 :: ('MESH:D008581', 'Disease') :: ['meningitis'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'abortive type of infection'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity7545 :: ('MESH:D017282', 'Disease') :: ['tick-borne disease', 'tick-borne diseases']
@entity5422 :: (MESH:D008590,Disease) :: ['meningoencephalitis']
