BACKGROUND: Early identification of @entity1 at risk for @entity8 provides an opportunity to prevent or delay its progression and decrease morbidity and mortality. Our hypothesis was that implementation of a targeted screening program in communities with high-risk populations would detect previously unidentified @entity1 with or at high risk for @entity740 ( @entity740 ) with a prevalence that exceeds that predicted for @entity740 in the general population. METHODS: @entity1 with @entity101 or @entity6 or a first-order relative with @entity101 , @entity6 , or @entity8 were screened for @entity8 risk factors. Blood pressure, blood @entity413 level, serum @entity1011 level, hemoglobin level, microalbuminuria, @entity811 , @entity4658 , body mass index, and estimated glomerular filtration rate (EGFR) were evaluated. RESULTS: Six thousand seventy-one eligible @entity1 were screened from August 2000 through December 2001: of these @entity1 , 68% were @entity1 , 43% were African American, 36% were white, 10% were Hispanic, and 5% were Native American. Most reported high-school education or more (84%) and health insurance coverage (86%). Twenty-seven percent met the screening definitions for @entity6 ; 64%, for @entity101 ; 29%, for microalbuminuria; 8%, for @entity417 ; 18%, for @entity811 ; 13%, for @entity4658 ; 5%, for elevated serum @entity1011 level; 16%, for reduced EGFR; and 44%, for @entity28 . Among @entity1 without a reported history of specified conditions, screening identified 82 @entity1 (2%) with @entity6 , 1,014 @entity1 (35%) with @entity101 , 277 @entity1 (5%) with elevated serum @entity1011 levels, 839 @entity1 (14%) with reduced EGFRs, and 1,712 @entity1 (29%) with microalbuminuria. Thirty-five percent of @entity1 with a history of @entity6 had elevated serum @entity413 levels at screening (> or =180 mg/dL [10 mmol/L]), and 64% with a history of @entity101 did not have blood pressure controlled to less than 140/90 mm Hg. Only 18% of @entity1 with a history of @entity6 and 31% with a reduced EGFR had blood pressure controlled to less than 130/80 mm Hg and less than 135/85 mm Hg, respectively. CONCLUSION: Targeted screening is effective in identifying @entity1 with previously unidentified or poorly controlled @entity8 risk factors, as well as @entity1 with a moderately decreased EGFR.

Early detection of XXXX in community settings: the Kidney Early Evaluation Program (KEEP).

@entity1 :: ('9606', 'Species') :: ['participants', 'Persons', 'women', 'persons'] @entity4658 :: ('MESH:D011776', 'Disease') :: ['pyuria'] @entity8 :: ('MESH:D007674', 'Disease') :: ['kidney disease'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anemia'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity740 :: ('MESH:D051436', 'Disease') :: ['CKD', 'chronic kidney disease'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity811 :: ('MESH:D006417', 'Disease') :: ['hematuria'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity8 :: (MESH:D007674,Disease) :: ['kidney disease']
