PURPOSE: To describe the frequency, nature, trends, predictors, and outcomes of chemotherapy-related hospitalizations (CRHs) among a nonselected population of @entity5 @entity1 treated at a community @entity5 center, and to explore the feasibility of implementing continuous quality improvement methodologies in routine oncology practice. METHODS: We conducted a prospective cohort study of consecutive adult @entity5 @entity1 who received chemotherapy at a community @entity5 center January 2003 to December 2006. Demographic, comorbidity, diagnosis, treatment, and laboratory data were collected via medical record abstraction. Hospitalizations were classified as chemotherapy related or unrelated by a multidisciplinary panel. @entity1 who experienced CRHs were compared with those who did not. Using a randomly sampled subset of cases and controls, we built a logistic regression model to identify independent predictors of @entity6192 . RESULTS: Of 2,068 chemotherapy recipients, 179 (8.7%) experienced 262 CRHs. Most hospitalizations were not chemotherapy related (73.7%). The mean monthly rate of @entity6192 was 1.5%, the median length of stay was 5 days, the most common type of @entity6192 was gastrointestinal (46.1%) followed by infectious (31.4%), and 0.9% of chemotherapy recipients had a fatal @entity6192 . Significant predictors of @entity6192 included having a comorbidity score of 3-4 versus 0 and having a higher @entity1011 level. CONCLUSIONS: Although the vast majority of chemotherapy recipients did not experience a @entity6192 , these events were, unfortunately, not without serious consequences. Care should be taken when offering chemotherapy to @entity1 with multiple comorbid conditions. Systematic efforts to monitor @entity137 can lead directly to improvements in quality of care.

Chemotherapy-related hospitalization among community XXXX center @entity1 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity6192 :: ('1392', 'Gene') :: ['CRH']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
