OBJECTIVE: The aim of the present study has been to determine the proliferative differences in oral @entity9338 by means the quantification of Ki- 67 expression. STUDY DESIGN: The tissue analyzed were the following ones: @entity8619 (n=10), @entity8407 (n=10), @entity1141 (n=10). Normal oral mucosa (n=10) was used as the control group. The antibody employed was monoclonal PP-67 (Sigma). Immunoperoxidase detection was employed using the streptavidin- @entity1885 complex. The quantification was carried out by a program of image analysis system Qwin colour RGB. In all cases 10 fields differences were scored. For analytic study were used analysis of the variance and Scheffe's exact test were used. The statistical significance level was considered to be P < 0.05. RESULTS: In all tissues analyzed there was some grade of proliferation in the basal layer, and in @entity1141 so much in basal as suprabasal layer. Of the analytic results we emphasize that there were differences statistically significant among mean of the positive nuclei per mm of length in normal mucosa and @entity12120 (p=0.031), and between normal mucosa, @entity9338 with @entity1141 . In these three cases the values were p=0.000. CONCLUSION: Ki-67 antigen is a marker of nuclear proliferation that allows to settle down the differences proliferatives between @entity8619 . Therefore it should take in consideration to think in successive studies that guide therapeutic attitude in these lesions in function of its positivity.

Study comparative of Ki-67 expression in XXXX . Quantitative analysis.

@entity1885 :: ('MESH:D001710', 'Chemical') :: ['biotin'] @entity8407 :: ('MESH:D007972', 'Disease') :: ['oral leukoplakia'] @entity9338 :: ('MESH:D008010', 'Disease') :: ['lichen planus and leukoplakia'] @entity12120 :: ('MESH:D007971', 'Disease') :: ['leukoplakia'] @entity8619 :: ('MESH:D017676', 'Disease') :: ['lichen planus and oral leukoplakia', 'oral lichen planus'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasia', 'dysplasias']
@entity8619 :: (MESH:D017676,Disease) :: ['oral lichen planus and oral leukoplakia']
