@entity816 ( @entity816 ) is a rare, @entity5 developing in @entity1 with @entity2916 ( @entity2916 ). Typical histopathological findings of this @entity5 are solid sheets and perivascular pseudorosettes of large, gemistocytic, polygonal and occasionally ganglion-like cells within a fibrillated background, accompanied by spindle-shaped cells creating broad fascicles. Rich @entity455 , and numerous calcifications are common. Mitoses, focal @entity39 , and endothelial proliferation are rarely encountered. In this study we report 3 cases of @entity816 out of 29 @entity2916 @entity1 , operated on in the Department of Neurosurgery, @entity1 's Memorial Health Institute, from 1990 to 2011 and retrospectively reviewed. These 3 cases exhibited distinct anaplastic features that might mimic @entity11 . Histologically, the @entity5 were composed of pleomorphic, gemistocytic, polygonal, ganglion-like or multinucleated cells arranged in sheets or forming perivascular pseudorosettes. Numerous foci of @entity39 , microvascular proliferation and high mitotic activity with atypical mito-tic figures were documented. The Ki67 labelling index was about 15-20%. These @entity5 might be confused with high-grade @entity11 and such a misleading diagnosis might result in @entity146 radio- or chemotherapy. Despite the common statement that morphological features of @entity4575 , i.e. pleomorphism, @entity39 , microvascular proliferation and increased mitotic activity, are not of prognostic value, the @entity5 behaviour in our cases seems to be more @entity146 and requires longer follow-up studies. We suggest recognizing such cases of @entity816 as atypical SEGAs.

XXXX with atypical histological features mimicking @entity11 .

@entity1 :: ('9606', 'Species') :: ['patients', 'Children'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular stroma'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour', 'tumours', 'neoplasm', 'benign brain tumour'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity11 :: ('MESH:D005910', 'Disease') :: ['malignant glioma', 'gliomas'] @entity2916 :: ('MESH:D014402', 'Disease') :: ['tuberous sclerosis complex', 'TSC'] @entity816 :: ('MESH:D001254', 'Disease') :: ['SEGA', 'Subependymal giant cell astrocytoma', 'subependymal giant cell astrocytoma'] @entity4575 :: ('MESH:D000708', 'Disease') :: ['anaplasia']
@entity816 :: (MESH:D001254,Disease) :: ['Subependymal giant cell astrocytomas']
