@entity420 with intestinal differentiation have been described in a wide variety of anatomical sites. To our knowledge, however, @entity420 with intestinal phenotype have not been described in the pancreas. We report here 11 @entity513 of the pancreas that were morphologically similar to @entity694 . These @entity3123 of intestinal type represented 10% of 110 consecutively removed @entity513 of the pancreas. All @entity4056 expressed @entity5822 , carcinoembryonic antigen, @entity6628 , and @entity5091 . The pattern of reactivity of @entity5822 and carcinoembryonic antigen was diffuse, whereas that of mucin 2 staining and @entity6628 nuclear labeling was focal and confined predominantly to goblet cells and less frequently to columnar cells. @entity189 contained collections of endocrine cells admixed with the columnar and goblet cells. @entity189 were associated with high-grade @entity788 of intestinal type. Six @entity1 were female and 5 were male. Their ages ranged from 52 to 76 years (mean age, 61 years). The clinical presentation did not differ from that of the @entity513 . All @entity189 originated in the head of the pancreas, and 5 had metastasized to the regional lymph nodes at the time of surgical resection. Only 1 @entity1 survived 5 years. Three @entity1 are disease free from 2.8 to 8.9 months after surgery. Six @entity1 died as a direct result of the @entity189 , and 1 was lost to follow-up. More studies are needed to determine the biologic behavior of this distinctive histologic variant of @entity1124 .

XXXX : a previously unrecognized histologic variant of @entity1124 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity3123 :: ('MESH:C562463', 'Disease') :: ['pancreatic carcinomas'] @entity6628 :: ('1045', 'Gene') :: ['CDX2'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic intraepithelial neoplasia'] @entity1124 :: ('MESH:D021441', 'Disease') :: ['ductal adenocarcinoma of the pancreas'] @entity5091 :: ('4583', 'Gene') :: ['MUC2'] @entity4056 :: ('MESH:D007414', 'Disease') :: ['intestinal type carcinomas'] @entity189 :: ('MESH:D002277', 'Disease') :: ['Five carcinomas', 'Six carcinomas', 'carcinomas'] @entity513 :: ('MESH:D044584', 'Disease') :: ['ductal carcinomas', 'conventional ductal carcinomas'] @entity5822 :: ('3855', 'Gene') :: ['cytokeratin 7'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colonic adenocarcinomas'] @entity420 :: ('MESH:D000230', 'Disease') :: ['ductal adenocarcinomas', 'Adenocarcinomas']
@entity420 :: (MESH:D000230,Disease) :: ['Intestinal type adenocarcinoma']
