PURPOSE OF REVIEW: @entity308 are a heterogeneous group of conditions that contribute significantly to impairments in quality of life, independent of the severity of @entity16 . @entity308 may predate neurological signs and symptoms in the evolution of @entity179 , and there is some evidence that @entity308 itself may be a risk factor in the aetiology of some @entity303 . This review aims to summarize the relevant current literature on diagnosis, aetiology and treatment of @entity308 in neurology. RECENT FINDINGS: Diagnosing @entity308 in neurological conditions can be particularly difficult because of communication difficulties and changes in emotional expression as a result of the underlying @entity16 . Rating scales loaded towards somatic symptoms can show poor validity for screening or rating of severity in this setting. The evidence for the treatment of @entity308 in @entity16 is scant, and often the treatment advice is based on consensus views of clinicians. Nevertheless, there have been some clinical trials, which are reported. SUMMARY: @entity308 is common in neurology. It is underrecognized and undertreated. Recent research has allowed us to define @entity308 more clearly in this setting. Trials of treatment are urgently needed, especially as @entity308 is a significant factor in quality of life and may affect prognosis.

XXXX : an update.

@entity303 :: ('MESH:D003704', 'Disease') :: ['dementias'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological disease', 'neurological illness'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression', 'depressive illness', 'Depressions', 'depression'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative disorders']
@entity16 :: (MESH:D009422,Disease) :: ['Depression in neurological disorders']
