BACKGROUND: Several methods have been developed to improve the efficacy of mechanical resuscitation, because organ perfusion achieved with conventional manual resuscitation is often insufficient. In animal studies, phased chest and abdominal compression-decompression resuscitation by use of the Lifestick device has resulted in a better outcome compared with that of conventional resuscitation. In end-of-life @entity1 , an increased coronary perfusion pressure was achieved. The aim of the present study was to determine the feasibility, safety, and efficacy of the Lifestick compared with conventional resuscitation in @entity1 with @entity1164 . METHODS AND RESULTS: The crews of 4 mobile intensive care units, staffed by an emergency physician and a paramedic, were trained to use the device. Fifty @entity1 were randomized by sealed envelopes to either Lifestick (n=24) or conventional (n=26) resuscitation. No differences were found regarding demographic and logistical conditions between the groups. Nineteen of the @entity1 (73%) with conventional resuscitation had @entity2224 , 13 of whom survived to hospital admission (no survivals with other @entity943 ) and 7 were discharged. In contrast, in the Lifestick-CPR group, only 9 @entity1 had @entity2224 (38%; P=<0.02; OR, 2.5; 95% CI, 0.6 to 10.6). Four of these 9 @entity1 and 5 of 15 @entity1 with other @entity943 survived to hospital admission, but none survived to hospital discharge. Autopsy in a subgroup of @entity1 who died at the scene revealed @entity130 with Lifestick than with conventional resuscitation. CONCLUSION: Lifestick resuscitation is feasible and safe and may be advantageous in @entity1 with @entity1167 or pulseless electric activity.

Phased chest and abdominal compression-decompression versus conventional cardiopulmonary resuscitation in out-of-hospital XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1164 :: ('MESH:D016757', 'Disease') :: ['sudden nontraumatic out-of-hospital cardiac arrest'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['ventricular fibrillation'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['asystole'] @entity943 :: ('MESH:D001145', 'Disease') :: ['arrhythmias'] @entity130 :: ('MESH:D014947', 'Disease') :: ['less injuries']
@entity1167 :: (MESH:D006323,Disease) :: ['cardiac arrest']
