The purpose of this study was to evaluate pediatric @entity1 with @entity1252 ( @entity1252 ) to determine 1) the incidence of @entity715 , 2) the incidence of antiphospholipid antibodies, and 3) whether there is an association between the presence of antiphospholipid antibodies and @entity715 . We performed a cross-sectional cohort study in 59 consecutive @entity1252 @entity1 who had been managed at rheumatology clinics in two pediatric hospitals. A history, questionnaire, and chart review were completed by the study nurse blinded to laboratory results. Only the @entity715 events that could be substantiated by review of radiographic tests were accepted. The presence of antiphospholipid antibodies was determined by prospective analysis for a @entity4555 and anticardiolipin antibodies on two separate occasions at least 3 mo apart. @entity1 were considered to be positive if one or more tests were positive on both occasions. Thirteen @entity715 events occurred in 10 of the 59 @entity1 (17%). Fourteen @entity1 (24%) were classified as positive for @entity4555 , and 19 @entity1 (27%) were classified as positive for anticardiolipin antibodies. A significant relationship between the presence of a @entity4555 and a @entity715 event was shown: odds ratio 28.7 (95% confidence interval 4.03-138.2, p < 0.001). A nonsignificant trend was seen for the presence of an anticardiolipin antibody and a @entity715 event: odds ratio 2.12 (95% confidence interval 0.71-22.8, p=0.08). We conclude that in pediatric @entity1 with @entity1252 : 1) a significant proportion of @entity1 have @entity715 events, 2) a significant proportion of patients have antiphospholipid antibodies, and 3) there is a significant relationship between the presence of a @entity4555 and @entity715 events.

The relationship of antiphospholipid antibodies to thromboembolic events in pediatric XXXX with @entity1252 : a cross-sectional study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis', 'thrombotic'] @entity4555 :: ('MESH:C531622', 'Disease') :: ['lupus anticoagulant'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE', 'systemic lupus erythematosus']
@entity1 :: (9606,Species) :: ['patients']
