UNASSIGNED: 195 Background: @entity1897 ( @entity1897 ) can affect lower @entity3325 leading to balance deficits and increased fall risk. This study evaluated the effect of a sensor-based exercise program on improving postural control in @entity5 @entity1 with @entity1897 . METHODS: Twenty two @entity5 @entity1 (Age 70.3  8.7 years) with objectively confirmed @entity1897 (vibration perception threshold test, VPT > 25 Volt) were randomized to twice weekly x 4 weeks sensor-based training including weight shifting and virtual obstacle crossing with real-time visual feedback of lower-extremities through wearable wireless sensors (intervention group, IG, n = 11) or no intervention (control group, CG, n = 11). Outcome measures included changes in sway of ankle, hip, and center of mass (CoM) in both medio-lateral (ML) and anterior-posterior (AP) directions during 30 second standing in feet closed position (both feet next to each other) with eyes open (EO) and eyes closed (EC), and semi-tandem position (big toe by arch of other foot) with EO, at baseline and post-intervention. All assessments were made using validated wearable sensors. RESULTS: VPT score averaged 49.6    26.7 Post intervention, sway of hip, ankle and CoM (ML) were significantly reduced in the IG compared to the CG during FC position (p = .010-.022). During the more challenging position of semi-tandem, all sway parameters except ankle were significantly reduced (p = .008-.039). Effect sizes were moderate-large (eta squared = .255-.388). CONCLUSIONS: This randomized controlled study using a novel wireless sensor-based training demonstrated improvements in balance in @entity1897 @entity1 by measures of balance that have been related to fall risk. We speculate that the sensor-based training with real-time @entity227 feedback provided @entity1 with enhanced information about joint movements and motor error in order to compensate for deteriorated/lost lower @entity3325 from @entity1897 . This balance training system can be easily translated to an in-home setting and may decrease fall risk and thus improve @entity5 @entity1 ' quality of life. CLINICAL TRIAL INFORMATION: NCT02043834.

Wearable sensor-based balance training in older @entity5 XXXX with chemotherapy-induced neuropathy: A randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual joint position'] @entity3325 :: ('MESH:D020886', 'Disease') :: ['extremity joint proprioception'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['Chemotherapy-induced peripheral neuropathy', 'CIPN']
@entity1 :: (9606,Species) :: ['patients']
