BACKGROUND: Preoperative assessment of gastro-esophageal junction (GEJ) @entity420 stage and its location according to Siewert are essential for planning the therapeutic approach. The present study was aimed at analyzing the utility of endoscopic ultrasonography (EUS) in evaluating GEJ @entity420 stage and whether this modality added to EGD improves assessment of Siewert type. METHODS: The results of 51 @entity1 studied by EGD plus EUS (EGD/EUS group) were compared with the results of 54 @entity1 studied by EGD only (EGD group). RESULTS: A differentiation of @entity2558 @entity5 was attempted by measurement of the @entity5 length using 4 cm as a criterion. This goal was not achieved because of a high rate of advanced @entity5 less than 4 cm (sensitivity and specificity were 81.3% and 34.2%, respectively). Conversely EUS ability in @entity2558 assessment was very reliable (92%). The accuracy in defining the Siewert type was 72.5% and 64.8% for EGD/EUS and EGD groups, respectively (P = 0.394). Some difficulties in distinguishing between @entity5 were observed in both groups with an extremely low specificity (44%) in classifying @entity5 by EGD group. CONCLUSIONS: EUS seems to be essential in differentiating @entity2558 from advanced @entity5 . It shows an accuracy in defining the Siewert type of 72.5%, with some difficulties in distinguishing from @entity5 .

Evaluation of Siewert classification in gastro-esophageal junction XXXX : What is the role of endoscopic ultrasonography?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2558 :: ('58492', 'Gene') :: ['pT1'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'type II tumors', 'type II and III tumors', 'tumors']
@entity420 :: (MESH:D000230,Disease) :: ['adenocarcinoma']
