OBJECTIVES: Prevalence of @entity194 ( @entity194 ) has been always investigated by phone or web interview without any objective evaluation. Objective signs associated with symptoms of @entity194 are now termed @entity790 ( @entity790 ). This multi-centric study was performed in order to provide nation-wide data on the prevalence and management of @entity790 . METHODS: Nine hundred thirteen females, 59.3  7.4 years old asking for a routine gynecological examination were recruited. Diagnosis of @entity790 was based on @entity1 sensation of vaginal dryness, any objective sign of @entity194 and a pH>5. RESULTS: A 722/913 (79.1%) @entity1 were diagnosed with @entity790 with a prevalence ranging from 64.7% to 84.2%, starting from 1 to 6 years after menopause. Sedentary @entity1 were at higher risk of @entity790 (OR 1.8, 95% CI: 1.3-2.5; p=0.0005). Recent @entity281 was more likely in @entity1 with @entity790 (OR 2.48, 95% CI: 1.33-4.62; p=0.0041). Symptoms reported by @entity1 with @entity790 were vaginal dryness (100%), @entity546 (77.6%), burning (56.9%), itching (56.6%) and @entity3833 (36.1%). Signs detected by gynecologists were @entity2133 (99%), thinning of vaginal rugae (92.1%), pallor of the mucosa (90.7%), @entity2100 (71.9%) and @entity4125 (46.7%). Only 274 (30%) of @entity1 had had a previous diagnosis of @entity194 / @entity790 . These were treated either with no therapy (9.8%), systemic hormone (9.2%), local hormone (44.5%) or local non-hormonal (36.5%) therapy. At the time of our investigation 266 of them (97.1%) still had the disorder. CONCLUSIONS: @entity790 is a common, under-diagnosed and under-treated disorder. Measures to improve its early detection and its appropriate management are needed.

@entity194 of XXXX in postmenopause. Results from a multicentric observational study: The AGATA study.

@entity1 :: ('9606', 'Species') :: ['women', 'patient'] @entity2133 :: ('MESH:D014987', 'Disease') :: ['mucosal dryness'] @entity4125 :: ('MESH:D011693', 'Disease') :: ['petechiae'] @entity281 :: ('MESH:D007239', 'Disease') :: ['vaginal infection'] @entity3833 :: ('MESH:D053159', 'Disease') :: ['dysuria'] @entity194 :: ('MESH:D001284', 'Disease') :: ['VVA', 'vulvar-vaginal atrophy'] @entity2100 :: ('MESH:D005600', 'Disease') :: ['mucosal fragility'] @entity546 :: ('MESH:D004414', 'Disease') :: ['dyspareunia'] @entity790 :: ('MESH:D014564', 'Disease') :: ['genitourinary syndrome of menopause', 'GSM']
@entity1 :: (9606,Species) :: ['women']
