BACKGROUND: @entity301 ( @entity301 ) is an important cause of morbidity and mortality in @entity454 ( @entity454 ). Prevention of @entity301 in @entity454 requires identification and treatment of coronary risk factors in @entity740 ( @entity740 ). METHODS: We evaluated the prevalence of "traditional coronary risk factors" in @entity740 in 1,795 @entity1 enrolled in the baseline period of @entity8 ( @entity8 ) Study. Using a cross-sectional design, we determined the relationship of these risk factors to the level of glomerular filtration rate (GFR) and @entity644 . We also predicted the @entity301 risk in the @entity8 Study baseline cohort using the coronary point score. RESULTS: 64.0% had blood pressure > or = 130/85 mmHg despite antihypertensive therapy. 64.2% had LDL @entity165 > or = 130 mg/dl, while 38.3% had HDL @entity165 < 35 mg/dl. After adjustment for age, gender and the presence of @entity6 , GFR was inversely associated with systolic blood pressure and positively associated with HDL @entity165 , but not associated with total or LDL @entity165 . After adjustment for age. gender and the presence of @entity6 , @entity644 was positively associated with systolic and diastolic blood pressure, total serum @entity165 and LDL @entity165 , and inversely associated with HDL @entity165 . Nonetheless, the predicted @entity301 risk, even at a very low GFR, was similar to the risk in the general population and lower than the observed rate of de novo @entity301 in incident dialysis @entity1 . CONCLUSIONS: "Traditional coronary risk factors" are highly prevalent in @entity740 and vary with the level of renal function. However, the coronary point score does not appear to explain the extent of increased @entity301 risk in @entity454 . Non-traditional risk factors may also contribute to @entity301 in @entity454 .

Cardiovascular disease risk factors in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity8 :: ('MESH:D007674', 'Disease') :: ['MDRD', 'Modification of Diet in Renal Disease'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity301 :: ('MESH:D003327', 'Disease') :: ['CHD', 'Coronary heart disease'] @entity740 :: ('MESH:D051436', 'Disease') :: ['chronic renal insufficiency', 'CRI'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal disease', 'ESRD']
@entity740 :: (MESH:D051436,Disease) :: ['chronic renal insufficiency']
