OBJECTIVE: To conduct a systematic review of studies reporting on the validity of @entity66 ( @entity66 ) codes for identifying @entity64 in administrative data. METHODS: MEDLINE and EMBASE were searched (inception to February 2015) for studies: (a) Using administrative data to identify @entity64 ; or (b) Evaluating the validity of @entity64 codes in administrative data; and (c) Reporting validation statistics (sensitivity, specificity, positive predictive value ( @entity2286 ), negative predictive value (NPV), or Kappa scores) for @entity64 , or data sufficient for their calculation. Additional articles were located by hand search (up to February 2015) of original papers. Studies solely evaluating codes for transient ischaemic attack were excluded. Data were extracted by two independent reviewers; article quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. RESULTS: Seventy-seven studies published from 1976-2015 were included. The sensitivity of @entity66 -9 430-438/ @entity66 -10 I60-I69 for any @entity66 was >=  82% in most [>=  50%] studies, and specificity and NPV were both >=  95%. The @entity2286 of these codes for any @entity66 was >=  81% in most studies, while the @entity2286 specifically for @entity64 was  <= 68%. In at least 50% of studies, PPVs were >=  93% for @entity510 ( @entity66 -9 430/ @entity66 -10 I60), 89% for @entity1779 ( @entity66 -9 431/ @entity66 -10 I61), and 82% for @entity64 ( @entity66 -9 434/ @entity66 -10 I63 or @entity66 -9 434_436). For in-hospital deaths, sensitivity was 55%. For @entity66 or @entity64 as a cause-of-death on death certificates, sensitivity was  <= 71% in most studies while @entity2286 was >=  87%. CONCLUSIONS: While most cases of prevalent @entity66 can be detected using 430-438/I60-I69 collectively, @entity64 must be defined using more specific codes. Most in-hospital deaths and death certificates with @entity64 as a cause-of-death correspond to true @entity64 deaths. Linking vital statistics and hospitalization data may improve the ascertainment of fatal @entity64 .

Validity of Diagnostic Codes for Acute XXXX in Administrative Databases: A Systematic Review.

@entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'ischaemic stroke', 'acute stroke'] @entity66 :: ('MESH:D004194', 'Disease') :: ['ICD', 'International Classification of Diseases', 'cerebrovascular disease'] @entity510 :: ('MESH:D013345', 'Disease') :: ['subarachnoid haemorrhage'] @entity2286 :: ('12211', 'Species') :: ['PPV'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['intracerebral haemorrhage']
@entity64 :: (MESH:D020521,Disease) :: ['Stroke']
