BACKGROUND/OBJECTIVES: Exercise is considered a protective factor in the prevention of type 2 @entity6 , although its role as a sole treatment for @entity6 remains unknown. The present meta-analysis compared the effect of exercise-only with exercise-diet interventions on plasma @entity413 levels among a pre- @entity6 population. SUBJECTS/METHODS: A literature search was conducted using PubMed, EMBASE and Cochrane databases. The Cochrane Collaboration tool was used to assess the quality of each trial. Two reviewers independently performed quality assessment of all included articles. A random effects model was used to calculate the pooled effect. RESULTS: A total of 4021 @entity1 from 12 studies were included in this meta-analysis, 2045 of them were in the intervention group and 1976 were in the control group. Compared with the exercise-only interventions, the exercise-diet interventions showed a significant effect on decreasing fasting plasma @entity413 (FPG) levels, with a @entity353 ( @entity353 ) =-0.22 mmol/l, 95% confidence interval (CI): -0.25, -0.18 (Z=12.06, P<0.05). The subgroup effect of exercise-only interventions did not produce a statistically significant result ( @entity353 =-0.09 mmol/l, 95% CI: -0.18, 0.00, Z=1.91, P>0.05). According to the intervention periods, the pooled effect in the    2-year group was the highest, and its @entity353 (95% CI) was -0.24   mmol/l (-0.43,-0.05). The pooled effects were statistically significant among the elderly and those of American and European descent, with @entity353 (95% CI) being -0.19   mmol/l (95% CI: -0.22, -0.15), -0.17   mmol/l (-0.21,-0.12) and -0.22   mmol/l (-0.27, -0.17), respectively. CONCLUSIONS: Evidence from published trials indicates that exercise-diet interventions showed a significant effect on decreasing FPG levels.European Journal of Clinical Nutrition advance online publication, 2 September 2015; doi:10.1038/ejcn.2015.128.

Comparison of control fasting plasma @entity413 of exercise-only versus exercise-diet among a pre- XXXX population: a meta-analysis.

@entity1 :: ('9606', 'Species') :: ['participants'] @entity353 :: ('MESH:D015431', 'Disease') :: ['WMD', 'weighted mean difference'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity6 :: ('MESH:D003920', 'Disease') :: ['pre-diabetes', 'diabetic', 'diabetes']
@entity6 :: (MESH:D003920,Disease) :: ['diabetic']
