1. In a previous study of the effects of @entity37555 ( @entity37555 ) on @entity1 undergoing athletic training, strength and performance increased, but not significantly more when the subjects were taking the drug than when they were taking placebo. The subjects did, however, gain more weight on the drug, with increases in total body @entity972 and muscle dimensions. It remained an open question whether the muscles had gained normal tissue or intracellular fluid. 2. In an attempt to distinguish between these possibilities the trial has been repeated, using as subjects seven male weight-lifters in regular training, and including measurements of total body @entity1568 . As before, a dose of 100 mg of @entity37555 /day was given alternately with the placebo in a double-blind crossover experiment. The treatment periods lasted 6 weeks and were separated by an interval of 6 weeks. Body weight, @entity972 and @entity1568 , muscle size, and leg performance and strength increased significantly during training on the drug, but not during the placebo period. 3. The finding of increased body @entity1568 suggested that the @entity1017 was not only intracellular fluid. The increases in body @entity972 (436 +/- SEM 41 mmol) and @entity1568 (255 +/- 69 g) were too large in proportion to the @entity1017 (2.3 +/- 0.4 kg) for this to be attributed to gain of normal muscle or other lean tissue, and imply gain of @entity1568 -rich, @entity1391 -poor substance. Although this action of @entity37555 might be described as anabolic, the @entity1017 produced is not normal muscle.

Effects of XXXX on the performance and body composition of @entity1 undergoing athletic training.

@entity1 :: ('9606', 'Species') :: ['men'] @entity1568 :: ('MESH:D009584', 'Chemical') :: ['nitrogen'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity1391 :: ('CHEBI:26020', 'Chemical') :: ['phosphate'] @entity37555 :: ('MESH:D008696', 'Chemical') :: ['methandienone', 'Dianabol'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium']
@entity37555 :: (MESH:D008696,Chemical) :: ['methandienone']
