AIM: Management of papillary breast lesions is a controversial issue, as complete excision implies surgery of numerous benign lesions. The purpose of this study was to assess concordance between percutaneous and surgical biopsy of @entity1185 along with factors predictive of @entity5 . @entity1 AND METHODS: The study consisted of a retrospective review of @entity1185 cases between 2009 and 2013 at three @entity0 centers. All cases of @entity1185 histologically diagnosed by percutaneous biopsy and confirmed by surgical specimen were included. The biopsy results were compared with final surgical pathology. Lesion size and clinical and radiological features were recorded. RESULTS: A total of 259 cases were included (188 simple and 71 @entity1185 ). Concordance between histology after percutaneous and surgical biopsy was lower for @entity1185 , regardless of type, than for simple @entity1185 (p<0.001). The risk of having a @entity1185 was shown to be significantly higher in postmenopausal @entity1 (p=0.023), and was 20 times higher if the percutaneous biopsy was malignant as opposed to benign (p<2.10). However, the false-negatives for percutaneous biopsy in @entity1185 cases were mainly related to atypical and in situ lesions. CONCLUSION: Percutaneous biopsy does not appear adequate for identifying @entity1185 requiring surgical excision due to the risk of underestimation of @entity5 . However, certain factors predictive of @entity5 may assist with surgical management, such as age and menopausal status, lesions peripheral to the nipple, and atypia on percutaneous biopsy.

The Role of Percutaneous Biopsy and Prognostic Factors of Malignancy in Solitary XXXX : A Retrospective Multicenter Study of 259 Cases.

@entity5 :: ('MESH:D009369', 'Disease') :: ['cancerous lesions', 'malignancy'] @entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity1185 :: ('MESH:D010212', 'Disease') :: ['papillomas', 'complex papilloma', 'complex papillomas', 'papilloma'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Papilloma']
