UNASSIGNED: 274 Background: The 2013 Community Oncology Practice Impact Report notes an increase of 20% in the number of community clinics closing since 2011. The objective of this study was to examine trends in location and reimbursement of chemotherapy in @entity1297 ( @entity1297 ) and @entity580 ( @entity580 ). METHODS: Using the MarketScan Research Databases, first administrations of bevacizumab and trastuzumab were identified from 1/1/2005 through 12/31/2012 for @entity1 with commercial or employer-sponsored supplemental Medicare insurance. Bevacizumab claims were excluded if the claim had a diagnosis related to @entity2194 . Claims for both drugs were excluded if the reimbursed amount was less than  100. Chemotherapy administration reimbursements were identified through CPT codes on the same day as the day as the drug charge. All claims were identified as occurring in OB or @entity580 . RESULTS: The percent of bevacizumab claims occurring in @entity580 increased from 6 to 34% among Medicare claims, and from 15 to 42% among commercial claims from 2005 to 2012. For trastuzumab, the increases were 4 to 35%, and 10 to 35% in Medicare and commercial claims, respectively. @entity580 reimbursements were consistently higher than @entity1297 reimbursements for chemotherapy administration and drug for both drugs across both payers. CONCLUSIONS: Although the differential in reimbursements between @entity580 and @entity1297 declined in the most recent two years, @entity580 reimbursements remained substantially higher while the shift in chemotherapy administration from @entity1297 to @entity580 has continued through 2012. Continued attention to reimbursement differences between @entity580 and @entity1297 is warranted and additional research is needed to more fully document the impact on @entity1 , providers, and payers. [Table: see text].

Trends in hospital and @entity1297 chemotherapy administration 2005-2012 for Medicare and commercially insured XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2194 :: ('MESH:D005128', 'Disease') :: ['macular degeneration or other eye disease'] @entity1297 :: ('MESH:D019292', 'Disease') :: ['OBS', 'office-based'] @entity580 :: ('MESH:D003428', 'Disease') :: ['outpatient hospital settings', 'OHS']
@entity1 :: (9606,Species) :: ['patients']
