BACKGROUND: Resection of an adjacent organ during gastrectomy for @entity356 is occasionally necessary to achieve margin clearance. The short- and long-term outcomes of this approach remain unclear. METHODS: @entity1 who underwent @entity356 resection in seven U.S. academic institutions from 2000 to 2012 were evaluated to compare perioperative morbidity, mortality, and survival outcomes, stratified by the need for and type of multivisceral resection (MVR). RESULTS: Of 835 @entity1 undergoing curative-intent gastrectomy, 159 (19 %) had MVR. The most common adjacent organs resected were the spleen (48 %), pancreas (27 %), liver segments 2/3 (14 %), and colon (13 %). As extent of resection increased (gastrectomy only, n = 676; MVR without pancreatectomy, n = 116; and MVR with pancreatectomy, n = 43), perioperative morbidity was higher: any complication (45, 60, 59 %, p = 0.012), major complication (17, 31, 33 %, p = 0.001), @entity834 (5, 11, 19 %, p < 0.001), and @entity1576 (9, 15, 22 %, p = 0.012). However, perioperative mortality did not significantly increase (30-day: 3, 4, 2 %, p = 0.74; 90-day: 6, 8, 9 %, p = 0.61). Overall survival after resection decreased as extent of resection increased (5-year: 42, 28, 6 %). After controlling for age, race, T stage, N stage, grade, margin status, perineural invasion, adjuvant therapy, and blood transfusion, MVR with pancreatectomy (HR 1.67, p = 0.044), but not MVR without pancreatectomy (HR 0.97, p = 0.759), remained an independent predictor of poor survival. CONCLUSION: In this modern, multi-institutional cohort of @entity356 @entity1 , multivisceral resection was associated with higher perioperative morbidity but not significantly higher perioperative mortality. If concomitant pancreatectomy is anticipated, @entity1 should be selected with extreme caution because long-term survival remains poor.

Multivisceral Resection for @entity356 : Results from the US XXXX Collaborative.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory failure'] @entity834 :: ('MESH:D057868', 'Disease') :: ['anastomotic leak'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer']
@entity356 :: (MESH:D013274,Disease) :: ['Gastric Cancer']
