OBJECTIVE: To determine the prevalence and the prognostic value of exercise-induced @entity943 (EIVA) in chronic @entity299 . STUDY DESIGN AND SETTING: An open prospective cohort of 130 clinically stable @entity1 at a University Hospital outpatient unit in Rio de Janeiro, Brazil, was followed up at scheduled clinical visits from 1990 through 2007. The endpoint was total cardiovascular mortality. Survival curves (Kaplan-Meier) and a multivariate Cox proportional hazard model were adjusted to determine the association between EIVA and mortality. RESULTS: The median duration of follow-up was 9.9 years (range, 132 days to 17 years). EIVA prevalence was 43.1% (95% CI: 34.5-51.7). Thirty-three @entity65 (25.4%) occurred. The hazard ratio of EIVA for @entity65 , after adjustment for age, was 1.84 (P = 0.09). An interaction was found between EIVA and @entity1283 on x-ray. In the group with @entity1283 , the hazard of dying was four times greater in the presence of EIVA (P for interaction = 0.05). CONCLUSION: In clinically stable chagasic subjects with @entity1283 , EIVA is a clinically significant marker of total cardiovascular mortality and may be a useful risk stratification tool in this population.

Prognostic value of exercise-induced XXXX in @entity299 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['cardiomegaly'] @entity299 :: ('MESH:D006331', 'Disease') :: ["Chagas' heart disease"] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmia'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular deaths', 'cardiovascular death']
@entity943 :: (MESH:D001145,Disease) :: ['ventricular arrhythmia']
