INTRODUCTION: @entity729 ( @entity729 ) associated to @entity740 ( @entity740 ) is a complex phenomenon closely related to mineral @entity2331 . Many are the factors implicated, as the drugs used in the treatment of @entity740 . Some in vitro studies suggest that electrolyte and @entity74 induced by hemodialysis (HD) may play a key role in @entity729 . METHODS: We analyzed electrolyte and @entity74 that occur during an HD session in 26 @entity1 randomly assigned to 1,25 mM or 1,5 mM @entity460 bath. RESULTS: There is a @entity460 load in all the @entity1 , independently of @entity460 bath concentration or basal serum @entity460 levels. At the end of the session, 100% of the @entity1 dialyzed with 1,5 mM @entity460 bath have @entity460 serum levels > 1,3 mM. However, this only occurs in 15% of the @entity1 dialysed with 1,25 mM @entity460 bath. During this @entity460 load, @entity3151 levels persist uncontrolled. Besides, there is a progressive alkalinization in all the @entity1 . In the end of the session 50% have serum @entity3157 > 30 mM and 23% pH > 7,5. CONCLUSIONS: During HD sessions occur electrolyte and @entity74 that induce @entity729 : @entity460 load and alkalization in presence of elevated @entity3151 levels. It is necessary to perform studies with kinetic models of @entity460 load and alkalinization different from the actual ones.

Haemodialysis session: The perfect storm for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3157 :: ('CHEBI:17544', 'Chemical') :: ['bicarbonate'] @entity740 :: ('MESH:D051436', 'Disease') :: ['CKD', 'chronic kidney disease'] @entity2331 :: ('MESH:D001851', 'Disease') :: ['bone metabolism disorders'] @entity74 :: ('MESH:D030342', 'Disease') :: ['acid-base disorders'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium', 'Calcium'] @entity729 :: ('MESH:D061205', 'Disease') :: ['Vascular calcification', 'VC'] @entity3151 :: ('MESH:D010758', 'Chemical') :: ['phosphorus']
@entity729 :: (MESH:D061205,Disease) :: ['vascular calcification']
