BACKGROUND: @entity1002 (GLS) is an early indicator of subclinical @entity299 , even when LV ejection fraction (LVEF) is normal, and is an independent predictor of @entity65 . Ambulatory blood pressure (BP) is a better predictor of @entity65 , including @entity712 , than office BP. We investigated the association of office and ambulatory BP measurements with subclinical LV @entity299 in a community-based cohort with normal LVEF. METHODS: Two-dimensional speckle-tracking echocardiography and 24-hour ambulatory BP monitoring were performed in 577 @entity1 (mean age 70  9 years; 60% @entity1 ) with LVEF >= 50% from the @entity65 and @entity75 (CABL) study. Univariable and multivariable linear regression analyses were used to assess the associations of BP measures with GLS. RESULTS: Higher ambulatory and office BP values were consistently associated with impaired GLS. After adjustment for pertinent covariates (age, sex, race/ethnicity, body mass index, @entity6 , @entity453 , LV mass index, and antihypertensive medication), office diastolic BP and ambulatory systolic and diastolic BPs (24-hour, daytime and nighttime) were independently associated with GLS (P = 0.003 for office @entity13520 , P  <= 0.001 for all ambulatory BPs). When ambulatory and office BP values were included in the same model, all ambulatory BP measures remained significantly associated with GLS (all P < 0.01), whereas office BP values were not. CONCLUSIONS: Ambulatory BP values are significantly associated with impaired GLS and the association is stronger than for office BP. Ambulatory BP monitoring might have a role in the risk stratification of @entity101 @entity1 for early @entity1002 .

Relationship of Office and Ambulatory Blood Pressure With XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity75 :: ('MESH:D001927', 'Disease') :: ['Brain Lesions'] @entity299 :: ('MESH:D006331', 'Disease') :: ['systolic dysfunction', 'cardiac dysfunction'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity13520 :: ('1628', 'Gene') :: ['DBP'] @entity65 :: ('MESH:D002318', 'Disease') :: ['Cardiovascular Abnormalities', 'cardiovascular events'] @entity1002 :: ('MESH:D018487', 'Disease') :: ['Left ventricular (LV) global longitudinal strain', 'LV dysfunction']
@entity1002 :: (MESH:D018487,Disease) :: ['Left Ventricular Global Longitudinal Strain']
