OBJECTIVE: @entity1 with @entity8222 have abnormal vascular supply to the palate, yet it is unknown whether there are increased postoperative healing problems following palatoplasty. This study investigated the correlation between @entity8222 and postoperative palatal @entity292 formation. DESIGN: Retrospective chart review was performed. @entity1 : @entity1 undergoing palatoplasty at @entity1 's Hospital Los Angeles from 1987 to 2000 were evaluated. Ten @entity1 with @entity8222 , 92 @entity1 with other syndromes and @entity2419 , and 458 nonsyndromic @entity1 with isolated @entity2419 were studied. INTERVENTIONS: All @entity1 were treated with a one-stage, double-reversing Z-plasty @entity2419 repair. MAIN OUTCOME MEASURES: Outcome measures included intraoperative observations of surgical anatomy and postoperative clinic follow-up of @entity292 formation. Palatal @entity292 rates between @entity1 with @entity8222 , other syndromes, and no syndrome were compared with chi-square analysis. RESULTS: @entity1 with @entity8222 had significantly greater palatal @entity292 rates (50%) than @entity1 with other syndromes (8.7%) or no syndrome (4.1%). @entity8222 @entity1 demonstrated large palatal @entity292 and poor flap vascularity. CONCLUSIONS: @entity1 with @entity8222 and @entity2419 have significantly higher palatal @entity292 risk than other @entity1 with @entity2419 when double-reversing Z-plasty palate repair is performed. Our findings suggest that @entity1 with @entity8222 and @entity2419 may have poor vascularity to @entity2419 created during palatoplasty. Furthermore, we recommend that surgeons performing palatoplasty minimize the dissection of mucoperiosteal flaps around the greater palatine arterial pedicle and utilize closure techniques creating the least vascular disruption of palatal tissue.

Increased @entity292 risk following palatoplasty in XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'Children', 'PATIENTS'] @entity2419 :: ('MESH:D002972', 'Disease') :: ['cleft palate', 'palatal flaps'] @entity8222 :: ('MESH:D008342', 'Disease') :: ['Treacher Collins syndrome', 'Treacher Collins'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula', 'fistulas']
@entity8222 :: (MESH:D008342,Disease) :: ['Treacher Collins syndrome']
