A 20-year-old male presented with persistent right @entity158 . Following ultrasound detection of testicular nodules and biopsy for intraoperative consultation which yielded @entity5 , he underwent radical orchidectomy. A predominantly whitish cyst and a lobulated, variegated nodule were identified. Histology showed a @entity44 with a focus of infiltrative epithelioid cells containing eosinophilic cytoplasm and pleomorphic nuclei, invading ectatic vessel wall associated with fibrinoid change. These cells were positive for cytokeratin, @entity1 placental lactogen and inhibin, while negative for @entity3059 , @entity4206 and @entity160 , consistent with @entity1470 ( @entity1470 ). The variegated nodule was a @entity5 composed of @entity189 and @entity44 . Aside from @entity1466 , primary @entity3567 such as @entity1470 , which are derived from intermediate trophoblasts, are extremely rare in the testis. Aside from a case of pure testicular @entity1470 , 2 other cases have been described in association with @entity5 , of which one is a mature teratoma with @entity1470 that demonstrated @entity1017 . The other presented with @entity1470 in retroperitoneal recurrence of a testicular @entity5 . We discussed the features of this @entity5 in the testis and important differentials in its diagnosis.

A rare case of combined XXXX with @entity44 and @entity5 in the testis.

@entity1 :: ('9606', 'Species') :: ['human'] @entity3567 :: ('MESH:D014328', 'Disease') :: ['trophoblastic tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['germ cell tumour', 'mixed germ cell tumour', 'tumour'] @entity1466 :: ('MESH:D002822', 'Disease') :: ['choriocarcinoma'] @entity4206 :: ('8626', 'Gene') :: ['p63'] @entity189 :: ('MESH:D002277', 'Disease') :: ['embryonal carcinoma'] @entity1470 :: ('MESH:D018245', 'Disease') :: ['PSTT', 'placental site trophoblastic tumor'] @entity160 :: ('174', 'Gene') :: ['alpha-fetoprotein'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['gain of chromosome 12p'] @entity3059 :: ('2315', 'Gene') :: ['Melan-A'] @entity158 :: ('MESH:D010146', 'Disease') :: ['testicular pain'] @entity44 :: ('MESH:D013724', 'Disease') :: ['immature teratoma', 'mature cystic teratoma']
@entity5 :: (MESH:D009369,Disease) :: ['placental site trophoblastic tumour']
