BACKGROUND/AIMS: The objective of this study was to evaluate the efficacy and safety of landiolol hydrochloride, a newly developed ultra-short-acting b1-selective blocker, for @entity86 after esophagectomy. METHODOLOGY: In total 231 @entity1 underwent transthoracic esophagectomy at the Department of Gastroenterological Surgery (Surgery II), Nagoya University Graduate School of Medicine from 2007 to 2012. Twenty-four @entity1 who were treated with either landiolol hydrochloride (n = 11) or conventional agents (combination of @entity460 channel blocker and digitalis preparation; control group, n = 13) for @entity86 after transthoracic esophagectomy were retrospectively analyzed. @entity591 was defined as a heart rate of >120 bpm or @entity955 . Hemodynamic changes, conversion rates, and adverse events were evaluated. RESULTS: The reduction in the heart rate at 1 h after medication was seen significantly more frequent in the @entity23893 group than in the control group. The time to conversion to sinus rhythm was also significantly shorter in the @entity23893 group. There were no significant differences between the two groups in blood pressure either before or after the medication. One @entity1 in the @entity23893 group showed @entity551 and @entity1168 , without serious consequences. CONCLUSIONS: Landiolol hydrochloride can be effectively and safely used in @entity1 who develop @entity591 after esophagectomy.

Effect of landiolol hydrochloride on XXXX after esophagectomy.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity591 :: ('MESH:D013610', 'Disease') :: ['tachyarrhythmia', 'Tachyarrhythmia'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative tachyarrhythmia'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity23893 :: ('MESH:C077049', 'Chemical') :: ['landiolol'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['bradycardia']
@entity591 :: (MESH:D013610,Disease) :: ['tachyarrhythmia']
