@entity420 is the most common histologic type of @entity1149 . The existence of @entity2 stem cells (CSCs) and epithelial-mesenchymal transition (EMT) in @entity1 tissue is controversy. The aim of this study is to investigate the expression and clinical significance of CSCs and EMT markers and evaluate the correlation between the two in @entity2220 . A total of 97 cases comprise the tissue microarray from surgical resection for primary @entity2220 . Immunohistochemistry for @entity14215 and @entity1759 as CSC markers and @entity5962 , @entity2277 , fibronectin, @entity11280 as EMT markers was performed. High @entity14215 expression was statistically associated with female gender (P=0.001), smoker (P=0.012), and high pT stages (P=0.046). High @entity1759 expression was statistically associated with female gender (P=0.008), non-smoker (P=0.000), and no @entity3 (P=0.039). High expression of @entity14215 was associated with good overall survival (P=0.021). High expression of @entity1759 was correlated with both good overall survival (P=0.024) and disease-free survival (P=0.000). @entity2277 expression was associated with pT stage (P=0.001) and @entity3 (P=0.028). @entity5962 , fibronectin and @entity11280 were not associated with clinicopathologic correlation and all EMT markers were not correlated with @entity2220 . CSC markers expression was not related to EMT. Our results showed that the expression of CSCs was associated with a good prognosis in @entity2220 . The prognostic significance of EMT markers was skeptical in this study. There is a need for more research about CSC, EMT, and the relation between these two in @entity1 @entity2220 .

Epithelial-mesenchymal transition in @entity1 of XXXX : correlation with cancer stem cell markers and prognosis.

@entity1 :: ('9606', 'Species') :: ['human'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['non-small cell lung carcinomas'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity5962 :: ('999', 'Gene') :: ['E-cadherin'] @entity1759 :: ('960', 'Gene') :: ['CD44'] @entity2277 :: ('7431', 'Gene') :: ['vimentin', 'Vimentin'] @entity3 :: ('MESH:D009362', 'Disease') :: ['pleural invasion'] @entity11280 :: ('6606', 'Gene') :: ['SMA'] @entity14215 :: ('216', 'Gene') :: ['ALDH1', 'ALDH1A1'] @entity420 :: ('MESH:D000230', 'Disease') :: ['Adenocarcinoma'] @entity2220 :: ('MESH:C538231', 'Disease') :: ['survival of lung adenocarcinoma', 'lung adenocarcinoma']
@entity420 :: (MESH:D000230,Disease) :: ['pulmonary adenocarcinoma']
