Biventricular pacing ( @entity3032 ) is emerging for @entity1 with @entity384 ( @entity384 ) and asynchrony. We measured basal asynchrony and early resynchronization by radionuclide angioscintigraphy (RNA) in order to predict long-term evolution of ventricular function after @entity3032 . Thirty-four @entity1 (NYHA Class III-IV,65.4 +/- 11 years) with large QRS(179 +/- 18 ms)were implanted with @entity3032 and studied by RNA before (D0), at day 8 (D8), and during follow-up(20 +/- 7 months). We calculated left and right ejection fractions, the @entity22286 (TRVLV), and the apicobasal dyssynchrony (Tab). LVEF improved from 20.2 +/- 8.1%(D0) to27.1%+/- 12.6%(follow-up,P < 0.003 vs D0) and RVEF from 28.6%+/- 13%(D0) to 34.3 +/- 11.5%(follow-up,P < 0.03 vs D0). Inter- (DeltaTRVLV) and intraventricular resynchronization was immediate and remained stable: TRVLV decreased from 68.3 +/- 38 ms(D0) to 13.4 +/- 48.5 ms(D8) and1.8 +/- 39.2 ms(follow-up,P < 0.0001 vs D0); and Tab from 45.8 +/- 64.1 msto-18 +/- 68(D8) and-28.3 +/- 53.6 ms(follow-up,P < 0.0001 vs D0). Early inter- and intraventricular resynchronization (DeltaTab) at D8 were related to late LVEF and RVEF improvement. Together, an LVEF > 15% and a significant @entity22286 (TRVLV > 60 ms) at D0 have a sensitivity of 79% and a positive predictive value of 83% to predict an improvement of LVEF superior to 5% at follow-up. In @entity384 @entity1 , @entity3032 resynchronizes ventricles early and in the long-term, while RVEF and LVEF improve progressively. @entity1 with large electromechanical dyssynchrony benefit most from @entity3032 .

Basal asynchrony and resynchronization with biventricular pacing predict long-term improvement of LV function in heart failure XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity384 :: ('MESH:D002311', 'Disease') :: ['DCM', 'dilated cardiomyopathy'] @entity3032 :: ('11657', 'Species') :: ['BiV'] @entity22286 :: ('MESH:C563239', 'Disease') :: ['interventricular dyssynchrony']
@entity1 :: (9606,Species) :: ['patients']
