BACKGROUND: Fatigue is prevalent in adult @entity5 survivors but less studied in childhood @entity5 survivors. Aims were to assess fatigue levels, prevalence of @entity5815 ( @entity5815 ) and the association of @entity5815 with health-related quality of life (HRQoL) in survivors of @entity3052 ( @entity3052 ), @entity6804 ( @entity6804 ), and @entity3969 ( @entity3969 ) in childhood. PROCEDURE: Seventy percent (398/567) of Nordic @entity1 treated for @entity3052 , @entity6804 , and @entity3969 between 1985 and 2001 at age >1 year responded to a postal survey, encompassing the Fatigue Questionnaire and the Short Form 36 (SF-36). @entity1 were divided into two groups at time of study; younger (YG, 13-18 years) and older (OG, 19-34 years). Respondents (19-34 years, n   =   763) from a Norwegian general population (GP) survey served as controls for the OG. RESULTS: The OG [mean age was 24 years (SD 3.3)] had higher fatigue levels compared to the YG and the GP, especially the females (P   <   0.05). There was also a higher prevalence of @entity5815 in the OG than in the GP (14 vs. 6%, P   <   0.001). Regardless of diagnosis, the OG with @entity5815 had poorer physical health (P   <   0.05) on the SF-36 but better mental health (P   <   0.05 and P   =   0.001) relative to controls with @entity5815 . CONCLUSIONS: The prevalence of @entity5815 is higher among Nordic survivors of @entity3052 , @entity6804 , and @entity3969 than GP controls of similar age. @entity5815 is associated with impaired HRQoL in survivors. However, they reported better mental health than @entity5815 GP controls. This might indicate different underlying mechanisms of @entity5815 in the two populations.

Increased prevalence of chronic XXXX : a population-based study.

@entity6804 :: ('MESH:D015192', 'Disease') :: ['IA', 'infratentorial astrocytoma'] @entity1 :: ('9606', 'Species') :: ['patients', 'Participants'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['acute myeloid leukemia', 'AML'] @entity5815 :: ('MESH:D015673', 'Disease') :: ['chronic fatigue', 'CF'] @entity3969 :: ('MESH:D009396', 'Disease') :: ['Wilms tumor', 'WT']
@entity5 :: (MESH:D009369,Disease) :: ['fatigue among survivors of childhood cancers']
