The marked fluctuation in symptoms with a spectrum of @entity146 contribute to misdiagnosis of @entity4676 . The authors review the recent progress in diagnosis and management with an emphasis on multidisciplinary approach. Possible associations with various genes have been found in etiology of @entity4676 . Development of the disease comes of dopaminerg neurotransmission disorder resulting in @entity9479 . Tics are brief movements or sounds that occur intermittently and unpredictably mimicking fragments of normal behavior. Diagnostic criteria are based on the motor and vocal phenomena and their dynamics. The key concept in management are the @entity1775 scaling correlating with quality of life measurements. Therapeutic interventions indicated at severe alteration in @entity1 's quality of life. Treatment plan combines various drug protocols, psychotherapy and behavioral therapy which should be optimalized for most disabling symptom. Social isolation and self injurious behavior complicates the treatment resistant, severe cases. In these subgroup of @entity1 , an adequate selection of stereotactic intervention could provide an effective control of @entity1775 or @entity146 . @entity4676 , as a typical @entity146 , is a striking example for improved efficacy of multidisciplinary approach.

[Multidisciplinary therapy of XXXX ].

@entity1 :: ('9606', 'Species') :: ['patient'] @entity1775 :: ('MESH:D020323', 'Disease') :: ['tic severity'] @entity146 :: ('MESH:D001523', 'Disease') :: ['behavioral disorder', 'behavioral problems', 'neuropsychiatric disorder'] @entity9479 :: ('MESH:D013786', 'Disease') :: ['cortico-striato-thalamic system dysfunction'] @entity4676 :: ('MESH:D005879', 'Disease') :: ['Tourette syndrome']
@entity4676 :: (MESH:D005879,Disease) :: ['Tourette syndrome']
