BACKGROUND: Recent findings have shown that the neutrophil-to-lymphocyte ratio (NLR) is prognostic for @entity674 ( @entity674 ). The platelet-to-lymphocyte ratio (PLR) can predict outcome for several other disease sites. This study evaluates the prognostic utility of NLR and PLR for @entity1 with @entity674 . METHODS: All @entity1 who had undergone surgical resection for primary, localized @entity674 from 2001 to 2011 were identified from a prospectively maintained database. @entity1349 ( @entity1349 ) was calculated by the Kaplan-Meier method and compared by the log-rank test. Univariate Cox proportional hazard regression models were used to identify associations with outcome variables. RESULTS: The study included 93 @entity1 . High PLR [>= 245; hazard ratio (HR) 3.690; 95  % confidence interval (CI) 1.066-12.821; p  =  0.039], neutrophils (HR 1.224; 95  % CI 1.017-1.473; p  =  0.033), and platelets (HR 1.005; 95  % CI 1.001-1.009; p  =  0.013) were associated with worse @entity1349 . @entity1 with high PLR had 2- and 5-year @entity1349 of 57 and 57  %, compared with 94 and 84  % for those with low PLR. High NLR (>= 2.04) was not associated with reduced @entity1349 (p  =  0.214). Whereas more @entity1 in the high PLR group had large @entity5 (p  =  0.047), more @entity1 in the high NLR group had high mitotic rates (p  =  0.016) than in the low-ratio cohorts. Adjuvant therapy was given to 41.2  % of the @entity1 with high PLR (p  =  0.022). The @entity1 with high PLR/NLR had worse nomogram-predicted @entity1349 than the @entity1 with low PLR/NLR. CONCLUSIONS: High PLR was associated with reduced @entity1349 . The prognostic ability of PLR to predict recurrence suggests that it may play a role in risk-stratification schemes used to determine which @entity1 will benefit from adjuvant therapy.

Predictive Ability of Blood Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['RFS', 'Recurrence-free survival'] @entity674 :: ('MESH:D046152', 'Disease') :: ['gastrointestinal stromal tumors', 'GIST']
@entity674 :: (MESH:D046152,Disease) :: ['Gastrointestinal Stromal Tumors']
