BACKGROUND: Delayed @entity356 (DGE) is a relatively common complication after pancreatoduodenectomy (PD). The aim of this study was to determine whether DGE is affected by antecolic or retrocolic reconstruction for gastro/duodenojejunostomy after PD. METHODS: A literature search was performed of the MEDLINE (PubMed), Ovid SP, ISI Web of Knowledge, EMBASE, and Cochrane databases to identify @entity23 ( @entity23 ) and clinical observational studies related to this topic from January 1995 to November 2014. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for categorical outcomes, and mean differences (MD) using fixed-effect and random-effects models were calculated for the meta-analysis. RESULTS: Fourteen studies including 1969 @entity1 met the inclusion criteria. Six studies were @entity23 , and eight studies were clinical observational studies. DGE was less common in the antecolic reconstruction group than in the retrocolic reconstruction group (OR = 0.24 [0.12-0.48], P  <  0.0001). Postoperative days to start solid foods (MD = -3.67  d [-5.10 to -2.33], P  <  0.00001) and length of hospital stay (MD = -2.90  d [-5.36 to -2.33], P  <  0.00001) were also significantly in favor of the antecolic reconstruction group. There was no difference in the incidence of @entity3472 , intra-abdominal fluid collection or abscess, @entity3116 , or mortality. However, in the subgroup analyses, using the data of six @entity23 or seven studies according to the International Study Group of Pancreatic Surgery definition, there was no significant difference in the incidence of DGE. CONCLUSIONS: Antecolic reconstruction for gastro/duodenojejunostomy does not seem to offer an advantage over retrocolic reconstruction with respect to DGE after PD.

Effects of antecolic versus retrocolic reconstruction for gastro/duodenojejunostomy on delayed XXXX after pancreatoduodenectomy: a systematic review and meta-analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity23 :: ('MESH:D007174', 'Disease') :: ['randomized controlled trials', 'RCTs'] @entity3472 :: ('MESH:D010185', 'Disease') :: ['pancreatic fistula'] @entity3116 :: ('MESH:D001658', 'Disease') :: ['biliary fistula'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric emptying']
@entity356 :: (MESH:D013274,Disease) :: ['gastric emptying']
