@entity6943 ( @entity6943 ), a causative agent of an emerging @entity166 , is endemic in the tropical regions of the world. Due to increased international travel, the infection is now also seen outside of the tropics. The majority of @entity1 with identified risk factors such as @entity6 , heavy @entity285 use, @entity740 , corticosteroid use, @entity2395 , @entity6331 , @entity1252 and @entity712 acquire this organism through percutaneous inoculation or inhalation. The clinical manifestations are variable, ranging from localized abscess formation to @entity295 . @entity79 are rarely reported but are an established entity. The knee joint is the most commonly affected joint in @entity6942 , followed by the ankle, hip and shoulder joints. @entity6942 should be in the differential diagnosis of @entity79 in residents or returning travelers from the endemic area. @entity6942 diagnosis is missed in many parts of the world due to the lack of awareness of this infection and limited laboratory training and diagnostic techniques. It also mimics other diseases such as @entity378 . Delay in the diagnosis, or the initiation of appropriate and effective treatment against @entity6942 , could worsen the outcome. Initial therapy with @entity5505 , or @entity2893 with or without @entity799 is recommended, followed by the oral eradication therapy (based on the antimicrobial susceptibility) with @entity115 / @entity798 or @entity799 . Surgical intervention remains important. This paper reviews current literature on the epidemiology, clinical features, diagnosis, and management of @entity79 .

@entity6943 Causing XXXX : A Clinical Update.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6331 :: ('MESH:D012214', 'Disease') :: ['rheumatic heart disease'] @entity712 :: ('MESH:D006333', 'Disease') :: ['cardiac failure'] @entity295 :: ('MESH:D018805', 'Disease') :: ['septicemia'] @entity5505 :: ('MESH:D002442', 'Chemical') :: ['ceftazidime'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity6943 :: ('28450', 'Species') :: ['Burkholderia pseudomallei', 'B. pseudomallei'] @entity799 :: ('MESH:D015662', 'Chemical') :: ['cotrimoxazole'] @entity115 :: ('MESH:D000658', 'Chemical') :: ['amoxicillin'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['systemic lupus erythematosus'] @entity740 :: ('MESH:D051436', 'Disease') :: ['malignancy, chronic lung and kidney disease'] @entity798 :: ('MESH:D019818', 'Chemical') :: ['clavulanic acid'] @entity79 :: ('MESH:D001847', 'Disease') :: ['melioidotic bone and joint infections', 'bone and joint infections', 'Melioidotic bone and joint infections'] @entity6942 :: ('MESH:D008554', 'Disease') :: ['Melioidosis', 'melioidosis'] @entity2893 :: ('CHEBI:46765', 'Chemical') :: ['carbapenem'] @entity285 :: ('D000431', 'Chemical') :: ['alcohol'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculosis'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious disease melioidosis'] @entity2395 :: ('MESH:D013789', 'Disease') :: ['thalassemia']
@entity79 :: (MESH:D001847,Disease) :: ['Bone and Joint Infections']
