PURPOSE: To evaluate technical feasibility and experimental usefulness of percutaneous US-guided implantation of @entity189 in @entity95 liver. MATERIALS AND METHODS: Forty-eight New Zealand White male @entity95 were used. @entity5 mass of @entity189 was harvested from carrier @entity95 , and minced @entity5 cells were implanted. Twenty-four @entity95 underwent percutaneous US-guided @entity5 implantation, and the same number of @entity95 underwent open @entity5 implantation. Tested parameters included technical success, procedural time, amount of anesthesia, recovery time, complications, @entity5 size, and regional @entity5 seeding. RESULTS: A new percutaneous US-guided implantation was technically feasible in all @entity95 . Evaluation parameters showed that the percutaneous US-guided implantation method is less invasive than the open laparotomy method. Targeting rate for left lateral lobe of implantation site was comparable in both methods (91.7% of percutaneous US-guided; 95.8% in open laparotomy). The success rate of @entity5 growth in the liver was 100% in both groups. However, in the group with US-guidance, @entity5 seeding developed more frequently in five of 24 @entity95 (20.8%) than in open laparotomy group (2/24, 8.3%). Five @entity95 had thoracoabdominal wall needle tract seeding, and two @entity95 had @entity5 seeding at both thoracoabdominal wall and intraperitoneal space. CONCLUSIONS: Percutaneous US-guided implantation of @entity189 in @entity95 liver is a less invasive alternative to open laparotomy, achieving equally successful @entity5 growth in the liver. Although percutaneous US-guidance implantation method may not be considered for long-term survival study design because of the possibility of @entity5 seeding, it can be considered for nonsurvival study design.

Percutaneous US-guided implantation of @entity189 into XXXX liver: a comparison with open surgical method.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Solid tumor', 'laparotomy tumor'] @entity95 :: ('9986', 'Species') :: ['rabbits', 'rabbit'] @entity189 :: ('MESH:D002277', 'Disease') :: ['Vx-2 carcinoma']
@entity95 :: (9986,Species) :: ['rabbit']
