UNASSIGNED: @entity1869 is believed to increase the risk of @entity1204 and represents a spectrum of morphologic and biological alterations of endometrial glands and stroma ranging from an exaggerated physiological state to @entity2735 . Considering the overlap between the various entities, it is not surprising that the morphologic assessment of @entity1478 is particularly challenging. This work aimed to evaluate @entity1478 according to their nuclear and glandular morphometric parameters, their D score, and their DNA ploidy, which help in making an accurate diagnosis. In this study, 50 endometrial biopsy specimens were stained with @entity1710 and @entity1711 for their histopathologic and morphometric study and Feulgen stain for DNA analysis. The cases were classified into 20 cases of @entity1869 , 10 cases of @entity1373 , and 20 cases of @entity1204 . Morphometric analysis of nuclear, glandular, and stromal parameters was performed using the Leica Qwin 500 image analysis system. In the studied cases, a significant difference was found in the mean values of the morphometrical parameters of @entity1478 , including the nuclear area and the nuclear roundness, and all glandular measurements including their complexity, area, volume percentage of stroma, and D score were significantly different. The DNA index and diploid and aneuploid values could differentiate significantly between @entity1478 . We conclude that nuclear morphometric evaluation of the @entity5072 and @entity3909 endometrium may be used as an ancillary technique in the diagnosis of atypical changes occurring in precancerous @entity1478 . In addition, DNA and D score assessment may be a reproducible and accurate predictor of the outcome of @entity1869 and may add some objective criteria for the correct diagnosis of difficult cases.

Morphometric and DNA Image Analysis of XXXX .

@entity1204 :: ('MESH:D016889', 'Disease') :: ['endometrial carcinoma'] @entity2735 :: ('MESH:D002278', 'Disease') :: ['carcinoma in situ'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['eosin'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['atypical hyperplasia'] @entity5072 :: ('MESH:D000796', 'Disease') :: ['hyperplastic'] @entity3909 :: ('MESH:D055756', 'Disease') :: ['carcinomatous'] @entity1710 :: ('MESH:D006416', 'Chemical') :: ['hematoxylin'] @entity1478 :: ('MESH:D014591', 'Disease') :: ['endometrial lesions'] @entity1869 :: ('MESH:D004714', 'Disease') :: ['Endometrial hyperplasia', 'endometrial hyperplasia', 'simple hyperplasia']
@entity1204 :: (MESH:D016889,Disease) :: ['Endometrial Hyperplasia and Carcinoma']
