BACKGROUND: Cardiovascular event is the major cause of mortality in @entity1 on maintenance hemodialysis. We prospectively tested the predictive values of @entity731 parameters for all-cause and cardiovascular outcomes in 219 hemodialysis @entity1 (age, 58 +/- 13 years; time on hemodialysis, 13 +/- 7 years; male/female, 144/75). METHODS: We measured blood @entity1255 ( @entity5784 ), ultrasound carotid artery @entity121 ( @entity121 ) and % aortic wall calcification at L2/3 region [% of calcification index in the abdominal aortic wall (%ACI)] by computed tomography (CT) scan, and followed all @entity1 for 5 years. RESULTS: During the follow-up periods, 54 @entity1 (25%) died, 40 (74%) of them of cardiovascular causes. @entity121 was significantly higher in @entity1 who expired (0.75 +/- 0.02 mm) than in those who survived (0.62 +/- 0.01 mm). @entity121 was significantly correlated with age (r = 0.47, P < 0.01) and %ACI (r = 0.27, P < 0.01). The survival rate during the observation was significantly lower in the final @entity121 third (58%) than in the first (90%) and the middle @entity121 third (80%) (P < 0.01). Multivariate Cox proportional hazards analysis revealed that @entity6 and @entity121 became independent determinants of all-cause and @entity65 . Adjusted hazards ratios of all-cause and cardiovascular mortality for an increase of 0.1 mm in @entity121 were 1.31 (95% CI, 1.07 to 1.59) and 1.41 (95% CI, 1.12 to 1.76). In contrast, %ACI at abdominal aorta and blood Hcy did not affect their 5-year mortality. CONCLUSION: These findings suggested that measurement of carotid artery @entity121 is useful for predicting long-term mortality in @entity1 receiving maintenance hemodialysis.

Impact of carotid atherosclerosis on long-term mortality in chronic hemodialysis XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity1255 :: ('MESH:D006710', 'Chemical') :: ['homocysteine'] @entity5784 :: ('CHEBI:17588', 'Chemical') :: ['Hcy'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic'] @entity121 :: ('MESH:D009135', 'Disease') :: ['intima media thickness', 'IMT'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular death']
@entity1 :: (9606,Species) :: ['patients']
