Near-infrared spectroscopy (NIRS) enables continuous non-invasive measurements of regional @entity26 saturation (rSO2). The aim was to evaluate the dynamics of rSO2 of the brain, preductal and postductal tissues during postnatal transition in preterm @entity1 with and without respiratory support (RS). This single-centre study was designed as an exploratory prospective observational study. Fifty one preterm @entity1 (>=  30 + 0 and  <  37 + 0   weeks) delivered by caesarean section  were included. RS using a T-Piece-Resuscitator and supplemental @entity26 were given according to guidelines. NIRS measurements were carried out by using Invos Monitor (Covidien; USA) for the first 15   min of life. Three NIRS transducers were attached on the forehead (rSO2brain), the right forearm (rSO2arm) and the left lower leg (rSO2leg). Two groups were compared based on need for RS: normal transition (NT) and RS group. RESULTS: In NT group rSO2brain increased over time and was significantly higher than rSO2arm, whereas in RS group rSO2brain and rSO2arm increased without significant differences. Courses of rSO2arm and rSO2leg increased over time and showed a converging pattern with initially lower values of rSO2leg in NT group and a diverging pattern with lower levels of rSO2leg in RS group. Overall, rSO2 levels were higher in NT compared to RS group. CONCLUSION: Our findings indicate that the decreased rSO2 levels in RS group compared to NT group are not only caused by lower arterial @entity26 saturation levels, but also by a compromised perfusion even in @entity1 with only mild @entity649 .

Even mild @entity649 alters tissue oxygenation significantly in preterm XXXX during neonatal transition.

@entity1 :: ('9606', 'Species') :: ['infants'] @entity649 :: ('MESH:D012128', 'Disease') :: ['respiratory distress'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen']
@entity1 :: (9606,Species) :: ['infants']
