PURPOSE: Current estimates of the proportion of @entity5 @entity1 who will require @entity138 are based almost entirely on expert opinion. The objective of this study was to estimate the proportion of incident cases of @entity14 that should receive @entity138 using an evidence-based approach. METHODS AND MATERIALS: A systematic review of the literature was undertaken to identify indications for @entity138 for @entity14 , and to ascertain the level of evidence that supported each indication. An epidemiologic approach was then used to estimate the incidence of each indication for @entity138 in a typical North American population of @entity14 @entity1 . The effect of sampling error on the estimated appropriate rate of @entity138 was calculated mathematically, and the effect of systematic error was estimated by sensitivity analysis. RESULTS: It was estimated that 23.7% +/- 1.0% of @entity14 cases develop one or more indications for @entity138 at some point in the course of the illness: 20.9% +/- 1.1% as part of their initial treatment, and 2.8% +/- 0.5% later for recurrence or progression. We estimated that 7.1% +/- 0.8% of @entity694 @entity1 will require @entity138 at some point in the course of the illness: 4.0% +/- 0.7% as part of their initial treatment, and 3.1% +/- 0.4% later for recurrence or progression. We estimated that 72.3% +/- 1.0% of @entity189 @entity1 will require @entity138 at some point in the course of the illness: 69.6% +/- 0.9% as part of their initial treatment and 2.7% +/- 0.2% later for recurrence or progression. CONCLUSIONS: This method provides a rational starting point for the long-term planning of radiation services, and for the audit of access to @entity138 at the population level. By completing such evaluations in the major @entity5 sites, it will be possible to estimate the appropriate @entity138 treatment rate for the @entity5 population as a whole.

An evidence-based estimate of the appropriate radiotherapy utilization rate for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity138 :: ('MESH:C563738', 'Disease') :: ['RT'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity189 :: ('MESH:D002277', 'Disease') :: ['rectal carcinoma'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon carcinoma']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal cancer']
