We report a case of @entity7555 in a 20-year-old @entity1 diagnosed after visiting an eye clinic with a chief complaint of reduced visual acuity. A male university student aged 20 years was referred to our department complaining of blurred @entity227 that had persisted for 1 month. He also noted @entity10 , @entity390 , and @entity809 in the lower extremities around the same time. The visual acuity of his right and left eye was 20/40 and 20/20, respectively. @entity3171 and @entity1713 were present. Brain magnetic resonance imaging showed no @entity1504 , while elevated cerebrospinal fluid pressure, reduced nerve conduction velocity in both lower extremities, @entity828 , M proteinemia, high blood @entity7 levels, osteoblastic and osteolytic changes in the spine, and atypical plasma cells in @entity79 were noted. From the above findings, the @entity1 was diagnosed with @entity7555 . He received high-dose @entity619 , @entity2816 , and radiotherapy on the sacral mass, followed by high-dose melphalan with autologous stem-cell support, and showed subsequent systemic and ophthalmologic improvement. Here, we report the youngest case ever of @entity7555 with @entity52469 . If @entity1 have @entity3171 in both eyes with no intracranial space-occupying lesion, @entity7555 should be considered in differential diagnosis, regardless of age.

POEMS Syndrome in a 20-year-old XXXX Diagnosed Following a Complaint of Reduced Visual Acuity.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity227 :: ('MESH:D014786', 'Disease') :: ['vision in both eyes'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity7 :: ('7422', 'Gene') :: ['VEGF'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['serous retinal detachment'] @entity809 :: ('MESH:D010292', 'Disease') :: ['paresthesia'] @entity2816 :: ('MESH:D013792', 'Chemical') :: ['thalidomide'] @entity52469 :: ('MESH:D005132', 'Disease') :: ['ocular manifestation'] @entity1504 :: ('MESH:D002561', 'Disease') :: ['intracranial abnormalities'] @entity828 :: ('MESH:C535727', 'Disease') :: ['hepatosplenomegaly'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone lesions'] @entity619 :: ('MESH:D003907', 'Chemical') :: ['dexamethasone'] @entity7555 :: ('MESH:D016878', 'Disease') :: ['POEMS syndrome'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity3171 :: ('MESH:C531767', 'Disease') :: ['Optic disc edema', 'optic disc edema']
@entity1 :: (9606,Species) :: ['Patient']
