OBJECTIVE: To evaluate the biological behavior of noninvasive @entity1377 of the endometrium. METHODS; From 1990 to 2001, all @entity1 with noninvasive uterine @entity1377 (UPSC) at three Southern California hospitals were identified from @entity5 registry databases. Data for analysis were collected from hospital charts, office records, and @entity5 registry files. RESULTS: Of the 100 @entity1 diagnosed with UPSC, 16 had noninvasive lesions. Twelve underwent a comprehensive surgical staging procedure with omental resection. Six of these 12 @entity1 were found to have disease beyond the uterine corpus, including 4 with adnexal involvement, 3 with omental disease, 2 with cervical extension, 1 with pelvic lymph node involvement, and 3 with positive washings. Three @entity1 were found to have positive cytology and @entity3 in more than one location. Of the 12 @entity1 , 1 of the 6 with stage IA disease had distant recurrence and 4 of the 6 with stage II-IV disease recurred. Of the remaining 4 @entity1 who underwent a staging procedure without pathologic omental assessment, 1 was found to have cervical extension. In these 4 @entity1 , 1 with stage IA disease recurred. CONCLUSION: The typical patterns of spread and prognostic factors for @entity4348 of the uterus do not apply to UPSC. In our series, omental assessment was necessary to detect the 25% of @entity1 with stage @entity66 due to omental involvement. Thus, @entity1 with noninvasive UPSC should undergo a comprehensive staging procedure including omental sampling to determine the extent of disease.

Significance of comprehensive surgical staging in noninvasive XXXX of the endometrium.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity1377 :: ('MESH:D002291', 'Disease') :: ['papillary serous carcinoma'] @entity66 :: ('MESH:D004194', 'Disease') :: ['IVB disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity4348 :: ('MESH:D018269', 'Disease') :: ['endometrioid carcinoma']
@entity1377 :: (MESH:D002291,Disease) :: ['papillary serous carcinoma']
