Previous randomized controlled trials (RCTs) and meta-analyses evaluated the efficacy and safety of adjunctive @entity288 for @entity497 ( @entity497 ). However, the results from them had large discrepancies. The eligibility criteria for the current meta-analysis were original RCTs written in English as a full article that evaluated adjunctive systemic @entity288 adding on antibiotic therapy targeting typical and/or atypical pathogen for treating hospitalized @entity1 @entity497 cases. Four investigators independently searched for eligible articles through PubMed, Embase, and Cochrane databases. Random model was used. The heterogeneity among original studies and subgroups was evaluated with the I(2) statistics. Of 54 articles that met the preliminary criteria, we found 10 eligible RCTs comprising 1780 cases. Our analyses revealed following pooled values by @entity288 . OR for all-cause death: 0.80 (95% confidence interval (95% CI) 0.53-1.21) from all studies; 0.41 (95% CI 0.19-0.90) from severe-case subgroup; 0.21 (95% CI 0.0-0.74) from intensive care unit (ICU) subgroup. Length of ICU stay: -1.30 days (95% CI (-3.04)-0.44). Length of hospital stay: -0.98 days (95% CI (-1.26)-(-0.71)). Length to clinical stability: -1.16 days (95% CI (-1.73)-(-0.58)). Serious complications do not seem to largely increase by @entity230 . In conclusion, adjunctive systemic @entity288 for hospitalized @entity1 with @entity497 seems preferred strategies.

Adjunctive Systemic XXXX for Hospitalized Community-Acquired Pneumonia: Systematic Review and Meta-Analysis 2015 Update.

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity497 :: ('MESH:D003147', 'Disease') :: ['CAP', 'community-acquired pneumonia'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity288 :: ('MESH:D000305', 'Chemical') :: ['corticosteroids']
@entity288 :: (MESH:D000305,Chemical) :: ['Corticosteroids']
