OBJECTIVE: Limited data are available on the risk of @entity65 in @entity3918 and PM. The purpose of this study was to estimate the risk of incident @entity583 ( @entity583 ) and @entity64 in adults with incident PM/ @entity3918 at the general population level. METHODS: We assembled a retrospective cohort of all adults with incident PM/ @entity3918 in British Columbia, and we matched up to 10 adults randomly selected from the general population. We estimated the incidence rates (IRs) per 1000 @entity1 -years for @entity583 and @entity64 . We calculated hazard ratios (HRs), adjusting for potential confounders. RESULTS: Among 774 new cases of @entity5442 , 424 had PM (59% female, mean age 60 years) and 350 had @entity3918 (65% female, mean age 56 years). IRs for @entity583 and @entity64 in PM were 22.52 and 10.15 events per 1000 @entity1 -years, respectively, vs 5.50 and 5.58 events in the comparison cohort, respectively. Fully adjusted HRs (95% CI) were 3.89 (95% CI: 2.28, 6.65) for @entity583 and 1.76 (95% CI: 0.91, 3.40) for @entity64 . The age-, sex- and entry time-matched HRs for @entity583 and @entity64 were highest in the first year after PM diagnosis (6.51, [95% CI: 3.15, 13.47] and 3.48 [95% CI: 1.26, 9.62], respectively). Similar trends were seen for @entity3918 . CONCLUSION: Our study demonstrates that PM and @entity3918 are both associated with an increased risk of @entity583 but not @entity64 . Our findings support increased vigilance in cardiovascular prevention, surveillance and risk modification in adults with PM and @entity3918 .

Risk of @entity583 and XXXX in adults with polymyositis and dermatomyositis: a general population-based study.

@entity1 :: ('9606', 'Species') :: ['person'] @entity64 :: ('MESH:D020521', 'Disease') :: ['ischaemic stroke', 'stroke'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity5442 :: ('MESH:D009220', 'Disease') :: ['inflammatory myopathies'] @entity3918 :: ('MESH:D009223', 'Disease') :: ['DM'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease']
@entity64 :: (MESH:D020521,Disease) :: ['ischaemic stroke']
