UNASSIGNED: Studies linking @entity308 and coronary artery @entity460 (CAC), a measure of subclinical @entity731 , have yielded mixed results. No longitudinal studies of @entity308 and CAC have included older adults of both genders. This study examined the association of @entity308 with CAC and CAC progression in older @entity1 and @entity1 . @entity1 were 417 community-dwelling older adults (mean age  = 67    7) with no history of @entity299 who attended a 1997 to 1999 research clinic visit when @entity308 were assessed using the Beck Depression Inventory (BDI). CAC was measured using electron-beam computed tomography in 2000 to 2002 and again in 2005 to 2007. Median BDI was 3, range  = 0 to 37; 39% of @entity1 and 10% of @entity1 had severe CAC (Agatston score >= 400) in 2000 to 2002. Ordinal logistic regression analyses examining the odds of greater compared with lesser CAC severity by BDI quartiles showed an unexpected negative association whereby @entity1 with the lowest @entity308 had 2.4 times the odds of increasing CAC severity compared with @entity1 in the second BDI quartile (95% CI 1.1 to 5.4). A nonlinear, U-shaped association was observed in @entity1 with those in the first and fourth BDI quartiles having 2.6 and 3.0 times higher odds of increasing CAC severity than subjects in the second quartile (95% CI 1.2 to 5.6 and 1.3 to 6.9, respectively) after adjustment for @entity301 risk factors. No significant associations were observed for CAC progression although similar nonlinear patterns were observed in @entity1 . In conclusion, our results suggest that @entity308 have a gender-specific, cross-sectional association with CAC but no statistically significant associations with CAC progression.

Relation of @entity308 With Coronary Artery XXXX Determined by Electron-Beam Computed Tomography (from the Rancho Bernardo Study).

@entity1 :: ('9606', 'Species') :: ['women', 'Participants', 'men'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive symptoms'] @entity301 :: ('MESH:D003327', 'Disease') :: ['coronary heart disease'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart disease'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis']
@entity460 :: (MESH:D002118,Chemical) :: ['Calcium']
