OBJECTIVE: To compare the effectiveness of @entity158 exposure physical therapy (PEPT) with conventional treatment in @entity1 with @entity158 ( @entity158 ) in a randomised controlled trial with a blinded assessor. SETTING: The study was conducted at a level 1 @entity130 centre in the Netherlands. @entity1 : 56 adult @entity1 with @entity158 participated. Three @entity1 were lost to follow-up. INTERVENTIONS: @entity1 received either PEPT in a maximum of five treatment sessions, or conventional treatment following the Dutch multidisciplinary guideline. MEASUREMENTS: Outcomes were assessed at baseline and at 3, 6 and 9   months after randomisation. The primary outcome measure was the Impairment level Sum Score-Restricted Version (ISS-RV), consisting of @entity227 ( @entity227 ), McGill Pain Questionnaire, active range of motion (AROM) and skin temperature. Secondary outcome measures included @entity158 Index (PDI); muscle strength; Short Form 36 (SF-36); disability of arm, shoulder and hand; Lower Limb Tasks Questionnaire (LLTQ); 10   m walk test; timed up-and-go test (TUG) and EuroQol-5D. RESULTS: The intention-to-treat analysis showed a clinically relevant decrease in ISS-RV (6.7 points for PEPT and 6.2 points for conventional treatment), but the between-group difference was not significant (0.96, 95% CI -1.56 to 3.48). @entity1 allocated to PEPT experienced a greater improvement in AROM (between-group difference 0.51, 95% CI 0.07 to 0.94; p=0.02). The per protocol analysis showed larger and significant between-group effects on ISS-RV, @entity227 , AROM, PDI, SF-36, LLTQ and TUG. CONCLUSIONS: We cannot conclude that PEPT is superior to conventional treatment for @entity1 with @entity158 . Further high-quality research on the effects of PEPT is warranted given the potential effects as indicated by the per protocol analysis. TRIAL REGISTRATION NUMBERS: NCT00817128 and NTR 2090.

Pain exposure physical therapy (PEPT) compared to conventional treatment in XXXX : a randomised controlled trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'Participants', 'PARTICIPANTS'] @entity227 :: ('MESH:D014786', 'Disease') :: ['VAS-pain', 'visual analogue scale for pain'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma'] @entity158 :: ('MESH:D010146', 'Disease') :: ['CRPS-1', 'complex regional pain syndrome type 1', 'pain', 'Pain Disability']
@entity158 :: (MESH:D010146,Disease) :: ['complex regional pain syndrome type 1']
