Massive accumulation of @entity1961 - @entity405 -TCRalphabeta+ cells in secondary lymphoid organs is characteristic of @entity1252 -prone MRL/lpr @entity19 . However, the role of these @entity784 ( @entity784 ) in @entity1 @entity1252 @entity1 receive only limited attention. Herein, we investigate the frequency of @entity784 in the peripheral blood mononuclear cells of forty seven Chinese @entity1 with @entity1252 ( @entity1252 ) and forty four normal individuals. @entity784 were measured with dual-fluorescence flow cytometry. The results showed that @entity784 only constituted a very minor subset of lymphocytes both in @entity1 and normals, it normally did not exceed 2% of the lymphocyte population. Compared with normal subjects, @entity1 with @entity1252 had slightly increased levels of @entity784 within the total lymphocyte population (0.66+/-0.45% vs 0.51+/-0.33%) or within TCRalphabeta+ population (1.14+/-0.88% vs 0.88+/-0.54%). The difference, however, did not reach statistical significance. The levels of @entity784 correlated neither with the titers of anti-DNA antibodies in sera nor with the presence of active and severe @entity1988 in @entity1252 @entity1 . Longitudinal follow-up of six @entity1 at the stages of active and inactive @entity1310 revealed similar levels of @entity784 in the same individual. The preliminary results suggest that circulating @entity784 do not appear to play a critical role in Chinese @entity1 with @entity1252 .

Double-negative (CD4- @entity405 -) TCRalphabeta+ cells in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity1310 :: ('MESH:D009393', 'Disease') :: ['nephritis'] @entity19 :: ('10090', 'Species') :: ['mice'] @entity784 :: ('MESH:D016399', 'Disease') :: ['DNT', 'double negative T cells'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE', 'systemic lupus erythematosus', 'lupus'] @entity1988 :: ('MESH:D008181', 'Disease') :: ['lupus nephritis'] @entity1961 :: ('12504(Tax:10090)', 'Gene') :: ['CD4'] @entity405 :: ('925', 'Gene') :: ['CD8']
@entity1252 :: (MESH:D008180,Disease) :: ['systemic lupus erythematosus']
