PURPOSE: To analyze the microbiologic spectrum and patterns of resistance of @entity1036 in @entity1 treated at a tertiary hospital in South Australia. METHODS: Retrospective review of microbiology laboratory records of all @entity1 with @entity1036 who had corneal scrapings, from 1998 to 2003. All records were subsequently reviewed for Gram staining and culture results, as well as antibiotic sensitivity and resistance. RESULTS Positive corneal cultures were obtained in 134 out of 211 @entity1 who had corneal scrapings (63.5%). Coagulase negative Staphylococcus was the commonest pathogen identified (29.8% of positive cultures), followed by @entity794 (18.7%), @entity796 (12.7%), Moraxella (6.7%), @entity7706 (6.0%), and @entity364 (5.2%). In 43.3% of culture positive cases, the organisms were also identified in Gram stain, and in all these cases there was a full correlation between the two methods. In vitro sensitivities were highest for @entity801 . Fourteen cases (35%) of coagulase negative Staphylococcus were found to be resistant to @entity7048 . No @entity2177 resistance was identified in all Pseudomonas isolates tested. CONCLUSIONS: Staphylococcus species continue to be the commonest causative organism for @entity1036 ; however, there is an emerging resistance to @entity7048 , which is commonly used as the first-line antibiotic for Gram-positive cocci. (Eur J Ophthalmol 2005; 15: 23-6).

XXXX in South Australia: Emerging resistance to cephazolinq.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity801 :: ('MESH:D005839', 'Chemical') :: ['gentamicin'] @entity7048 :: ('MESH:D002437', 'Chemical') :: ['cephazolin'] @entity796 :: ('287', 'Species') :: ['Pseudomonas aeruginosa'] @entity7706 :: ('MESH:D011008', 'Disease') :: ['Streptococcus pneumonia'] @entity1036 :: ('MESH:D007634', 'Disease') :: ['infectious keratitis'] @entity794 :: ('1280', 'Species') :: ['Staphylococcus aureus'] @entity2177 :: ('MESH:D002939', 'Chemical') :: ['ciprofloxacin'] @entity364 :: ('MESH:D009181', 'Disease') :: ['fungal keratitis']
@entity1036 :: (MESH:D007634,Disease) :: ['Infectious keratitis']
