BACKGROUND: In @entity1 with @entity6 and multivessel disease, @entity453 bypass graft surgery and percutaneous coronary intervention are treatment options. However, there is paucity of data comparing @entity453 bypass graft surgery against newer generation stents. METHODS AND RESULTS: @entity1 included in the New York State registries who had @entity6 and underwent isolated @entity453 bypass graft surgery or percutaneous coronary intervention with @entity2239 eluting stent (EES) for multivessel disease were included. Propensity score matching was used to assemble a cohort with similar baseline characteristics. The primary outcome was all-cause mortality. Secondary outcomes were @entity583 ( @entity583 ), @entity64 , and repeat revascularization. Short-term (within 30 days) and long-term outcomes were evaluated. Among 16   089 @entity1 with @entity6 and multivessel disease, 8096 @entity1 with similar propensity scores were included. At short-term, EES was associated with a lower risk of @entity204 (hazard ratio [HR] =0.58; 95% confidence interval [CI], 0.34-0.98; P=0.04) and @entity64 (HR=0.14; 95% CI, 0.06-0.30; P<0.0001) but higher risk of @entity583 (HR=2.44; 95% CI, 1.13-5.31; P=0.02). At long-term, EES was associated with a similar risk of @entity204 (425 [10.50%] versus 414 [10.23%] events; HR=1.12; 95% CI, 0.96-1.30; P=0.16), a lower risk of @entity64 (118 [2.92%] versus 157 [3.88%] events; HR=0.76; 95% CI, 0.58-0.99; P=0.04) but a higher risk of @entity583 (260 [6.42%] versus 166 [4.10%] events; HR=1.64; 95% CI, 1.32-2.04; P<0.0001) and repeat revascularization (889 [21.96%] versus 421 [10.40%] events; HR=2.42; 95% CI, 2.12-2.76; P<0.0001). The higher risk of @entity583 was not seen in the subgroup of EES @entity1 who underwent complete revascularization (HR=1.37; 95% CI, 0.76-2.47; P=0.30). CONCLUSIONS: In @entity1 with @entity6 and multivessel disease, EES was associated with lower upfront risk of @entity204 and @entity64 when compared with @entity453 bypass graft surgery. However, at long-term, EES was associated with similar risk of @entity204 , a higher risk of @entity583 (in those with incomplete revascularization), and repeat revascularization but a lower risk of @entity64 .

XXXX Eluting Stents Versus Coronary Artery Bypass Graft Surgery for @entity1 With @entity6 and Multivessel Disease.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity2239 :: ('MESH:C107135', 'Chemical') :: ['everolimus'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity2239 :: (MESH:C107135,Chemical) :: ['Everolimus']
