1. The everted small intestine of the new-born @entity1707 transports albumin to its serosal surface at rates which depend on the ionic composition of the bathing medium.2. Albumin transport takes place most rapidly at @entity1372 and @entity972 concentrations of 120 and 6 mM respectively. Increasing the concentration of @entity1372 or @entity972 , or decreasing the concentration of @entity1372 , reduces the net transfer of albumin.3. Albumin can increase the serosal transfer of @entity1372 , @entity972 and water. The calculated ionic composition of fluid transported in the presence of albumin closely resembles that presented to the mucosal surface over a wide range of @entity1372 and @entity972 concentrations.4. Lowering the concentration of @entity1372 reduces water transfer but only if albumin is present in the mucosal medium. Albumin-stimulated water transfer is only seen when the external concentration of @entity1372 is high.5. Raising the concentration of @entity972 reduces water transport, whether or not albumin is present, but this reduction is too small to account for the inhibitory effect of @entity972 on albumin transport.6. The mutual interaction that exists between the transport of albumin and @entity1372 is probably responsible for the increased @entity972 transport seen at low external concentrations of @entity972 . Higher concentrations of @entity972 appear directly to inhibit the interaction between the transport of @entity1372 and albumin.

Ionic dependence of protein transport across the new-born XXXX intestine.

@entity1707 :: ('9823', 'Species') :: ['pig'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium']
@entity1707 :: (9823,Species) :: ['pig']
