BACKGROUND: Persistent @entity308 below the threshold criteria for @entity308 represent a chronic condition with high risk of progression to a diagnosis of @entity308 . The evidence base for psychological treatments such as @entity1 -Centred Counselling and Low-Intensity Cognitive Behavioural Therapy for sub-threshold @entity308 and mild @entity308 is limited, particularly for longer-term outcomes. METHODS: This study aimed to test the feasibility of delivering a randomised controlled trial into the clinical and cost effectiveness of Low-Intensity Cognitive Behavioural Therapy versus @entity1 -Centred Counselling for @entity1 with persistent sub-threshold @entity308 and mild @entity308 . The primary outcome measures for this pilot/feasibility trial were recruitment, adherence and retention rates at six months from baseline. An important secondary outcome measure was recovery from, or prevention of, @entity308 at six months assessed via a structured clinical interview by an independent assessor blind to the @entity1 's treatment condition. Thirty-six @entity1 were recruited in five general practices and were randomised to either eight weekly sessions of @entity1 -centred counselling each lasting up to an hour, or up to eight weeks of cognitive-behavioural self-help resources with guided telephone support sessions lasting 20-30 minutes each. RESULTS: Recruitment rate in relation to the number of @entity1 approached at the general practices was 1.8  %. @entity1 attended an average of 5.5 sessions in both interventions. Retention rate for the 6-month follow-up assessments was 72.2  %. Of @entity1 assessed at six months, 71.4  % of @entity1 with a diagnosis of mild @entity308 at baseline had recovered, while 66.7  % with a diagnosis of persistent subthreshold @entity308 at baseline had not developed @entity308 . There were no significant differences between treatment groups for both recovery and prevention of @entity308 at six months or on any of the outcome measures. CONCLUSIONS: It is feasible to recruit @entity1 and successfully deliver both interventions in a primary care setting to @entity1 with subthreshold and mild @entity308 ; however recruiting requires significant input at the general practices. The evidence from this study suggests that short-term @entity1 -Centred Counselling and Low-Intensity Cognitive Behaviour Therapy are potentially effective and their effectiveness should be evaluated in a larger randomised controlled study which includes a health economic evaluation. TRIAL REGISTRATION: Current Controlled Trials ISRCTN60972025 .

Counselling versus low-intensity cognitive behavioural therapy for persistent sub-threshold and mild XXXX (CLICD): a pilot/feasibility randomised controlled trial.

@entity1 :: ('9606', 'Species') :: ['participants', 'Person', 'Patients', 'patients', 'participant', 'person'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive symptoms', 'depression', 'major depression']
@entity308 :: (MESH:D003866,Disease) :: ['depression']
