PURPOSE: To evaluate the reproducibility and reliability of Optical Coherence Tomography scans (OCT) obtained using the Time Domain (TD-OCT) StratusTM OCT, and the Spectral Domain (SD-OCT) SpectralisTM and CirrusTM OCT devices before and after manual correction in eyes with either Neovascular (NV- @entity13785 ) or Non-Neovascular (NNV- @entity13785 ) Age-related @entity1020 . METHODS: We conducted a prospective observational study of 36 @entity1 (50 eyes) with NV- @entity13785 or NNV- @entity13785 at a university-based retina practice. OCT scans were taken simultaneously using one TD-OCT and two SD-OCT devices. Macular thickness measurements were assessed before and after correction of the OCT algorithm by constructing Bland-Altman plots for agreement and calculating intraclass correlation coefficients (ICCs) and coefficients of repeatability (COR) to evaluate intraclass repeatability. RESULTS: The Spectralis device had the highest number of images needing manual correction. All machines had high ICCs, with Spectralis having the highest. Bland-Altman plots indicated that there was low agreement between both Cirrus    and Stratus    and Spectralis    and Stratus   , while there was good agreement between the Cirrus    and Spectralis    devices. The CORs were lowest for SpectralisTM and similar with each other and had higher values for CirrusTM and StratusTM. Agreement, CORs, and ICCs generally improved after manual correction, but only minimally.    CONCLUSION: Agreement is low between devices, except between both SD-OCT machines. Manual correction tends to improve results.

Reliability and reproducibility of spectral and time domain optical coherence tomography images before and after correction for XXXX with age-related @entity1020 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1020 :: ('MESH:D008268', 'Disease') :: ['Macular Degeneration'] @entity13785 :: ('MESH:D006009', 'Disease') :: ['AMD']
@entity1 :: (9606,Species) :: ['patients']
