OBJECTIVE: To investigate the relation between perioperative @entity4854 and complications after pancreatoduodenectomy. BACKGROUND: Perioperative @entity4854 is associated with complications after various types of surgery. This relation was never investigated for pancreatoduodenectomy. METHODS: In a consecutive series of 330 @entity1 undergoing pancreatoduodenectomy, @entity413 values were collected from the hospital information system during 3 periods: pre-, intra-, and early postoperative. The average @entity413 value per period was calculated for each @entity1 and divided in duals according to the median group value. Odds ratios for complications were calculated for the upper versus lower dual, adjusted for age, sex, American Society of Anesthesiologists Classification, body mass index, @entity6 , intraoperative blood transfusion, duration of surgery, intraoperative insulin administration, and octreotide use. The same procedures were carried out to assess the consequences of increased @entity413 variability, expressed by the standard deviation. RESULTS: Average @entity413 values were 135 (preoperative), 133 (intraoperative) and 142 mg/dL (early postoperative). Pre- and intraoperative @entity413 values were not associated with @entity260 . Early postoperative @entity4854 (>= 140 mg/dL) was significantly associated with complications [odds ratio (OR) 2.9, 95% confidence interval (CI), 1.7-4.9]. Overall, high @entity413 variability was not significantly associated with @entity260 , but early postoperative @entity1 who had both high @entity413 values and high variability had an OR for complications of 3.6 (95% CI, 1.9-6.8) compared to the lower @entity413 dual. CONCLUSIONS: Early postoperative @entity4854 is associated with @entity260 after pancreatoduodenectomy. High @entity413 variability may enhance this risk. Future research must demonstrate whether strict @entity413 control in the early postoperative period prevents complications after pancreatoduodenectomy.

Early postoperative XXXX is associated with @entity260 after pancreatoduodenectomy.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity4854 :: ('MESH:D006943', 'Disease') :: ['hyperglycemia'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity4854 :: (MESH:D006943,Disease) :: ['hyperglycemia']
