BACKGROUND: @entity1 with Streptococcus bovis @entity884 have an increased prevalence of advanced @entity694 ; however, an association with fecal carriage of the organism is unclear. @entity17518 has been shown to promote @entity694 in preclinical studies. The aim of this study was to examine the effect of @entity17518 fecal carriage on the long-term risk of @entity694 . @entity1 AND METHODS: @entity1 were prospectively recruited before colonoscopy. @entity17518 was detected by culture in stool, colonic fluid aspirates, and biopsies. @entity1 continued colonoscopic surveillance at intervals according to accepted guidelines. The National Cancer Registry was checked for diagnoses of @entity14 on 31 December 2014. RESULTS: A total of 118 @entity1 were recruited [75 (72.8%) @entity1 , aged 64.5  9.3 years] including 15 with @entity17518 . The mean duration of follow-up was 190.7  123.5 months. @entity694 was detected at colonoscopy in six (40.0%) and 49 (47%) @entity1 with and without @entity17518 , respectively (P=0.78). At the end of follow-up, @entity14 had developed in one (6.7%) @entity17518 -positive and six (5.8%) @entity17518 -negative @entity1 (P=1.00). CONCLUSION: Fecal carriage of @entity17518 at baseline is not associated with an increased long-term risk of developing @entity694 in this longitudinal study.

Colonic carriage of Streptococcus bovis and XXXX : a prospective 17-year longitudinal case-control study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS', 'men'] @entity17518 :: ('58097', 'Species') :: ['S. bovis'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity694 :: ('MESH:D003110', 'Disease') :: ['Colonic neoplasia', 'colonic neoplasia'] @entity884 :: ('MESH:D004696', 'Disease') :: ['infective endocarditis']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal neoplasia']
