OBJECTIVE: To analyze the surgical treatment results of 52 @entity1 with sacral @entity3580 . METHODS: This retrospective study included 52 cases of sacrococcygeal @entity3580 surgically treated from December 1996 to July 2001 at the Department of Orthopaedic Surgery, Peking University @entity1 's Hospital, The ages of @entity1 ranged from 18 to 80 years (mean 57 years), including of 35 males and 17 females. Nineteen @entity1 had received surgical management at least once and 9 of them had received radiation therapy, whereas the other 33 @entity1 had no surgery before they came to our department. Posterior approach and combined anterior-posterior approach were used in 43 and 9 cases respectively. RESULTS: Based on a recent follow-up, 4 @entity1 had died, and 3 of them died of metastatic @entity3580 . Among the other 46 @entity1 who stayed alive, 35 were free from disease. The average follow-up time of the 35 disease-free @entity1 was 42 months. In the 50 @entity1 whose sacral nerve roots had been reserved bilaterally at and above S3 level, the sphincter muscle function of bladder and bowl was good, whereas the function of @entity121 in 2 @entity1 with nerve roots reserved only at and above S1 level. To manage these 2 @entity1 , indwelling bladder catheters were used, but colostomy had not been performed. Local recurrence was observed in 7 of the 33 @entity1 (21%) with the first surgery, and in 5 of the other 19 @entity1 with second or third surgery. CONCLUSION: Complete resection of @entity5 (radical surgery when possible) is the most effective way to manage sacrococcygeal @entity3580 . Postoperative adjuvant radiation therapy can reduce the @entity5 recurrence rate, but it also can cause troubles that would hinder further surgical managements. Even if the @entity5 is relatively huge and the upper resection margin is as high as at S1 or S2 level, the @entity5 can be removed successfully by posterior approach and the @entity260 could be accepted. Though proper surgical procedures and adjuvant radiation can control the @entity5 locally, we have no optimal methods to prevent @entity3 from developing or to cure them when they are detected. One @entity1 who developed @entity3 in lungs received chemotherapy, and good curative effect had been observed.

[Surgical management of sacrococcygeal XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'People'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity3580 :: ('MESH:D002817', 'Disease') :: ['chordomas', 'chordoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity121 :: ('MESH:D009135', 'Disease') :: ['sphincter muscle impaired']
@entity3580 :: (MESH:D002817,Disease) :: ['chordomas']
