PURPOSE: To determine values of combinations of @entity650 ( @entity650 )/cervical native @entity10116 ( @entity10116 )/total @entity10116 (Premaquick  ) in predicting spontaneous deliveries and spontaneous exclusive preterm deliveries in @entity1 with threatened @entity3152 . METHODS: @entity1 with singleton pregnancies between gestation age (GA) of 24 weeks and 36 weeks and 6 days with @entity3152 were recruited during a prospective multicenter study. Premaquick   was positive when at least two of three biomarkers were positive. Sensitivity, specificity, positive predictive value ( @entity2286 ), negative predictive value (NPV) and accuracy were estimated for both prediction of spontaneous deliveries and spontaneous exclusive preterm deliveries. RESULTS: Ninety-seven (99.0%) out of 98 @entity1 enrolled were analyzed. Based on delivery status 7/14 days post-enrollment of general study population, Premaquick   had a sensitivity of 87.1/85.7%, a specificity of 92.4/96.8%, a @entity2286 of 84.4/93.8% and a NPV of 93.9/92.3% for prediction of spontaneous delivery. Predictive accuracy of Premaquick   test in relation to days of enrollment were: 90.7% (<= 7 days) and 92.8% (<= 14 days). For @entity1 enrolled at GA <35 weeks, Premaquick   had a sensitivity of 100.0/87.5%, a specificity of 94.1/96.9%, a @entity2286 of 70.5/87.5%, a NPV of 100.0/96.9% and an accuracy of 95.0/95.0% for prediction of preterm delivery within 7/14 days of enrollment, respectively. @entity2286 was most significantly different in both groups when outcomes were compared between 2 days and 14 days post-enrollment (P<0.001). CONCLUSION: This novel triple biomarker model of native and total @entity10116 and @entity650 appears to be an accurate test in predicting spontaneous deliveries and spontaneous exclusive preterm deliveries in threatened @entity3152 in singleton pregnancies.

Accuracy of a combined @entity10116 / XXXX test (Premaquick) in predicting delivery in @entity1 with threatened @entity3152 .

@entity1 :: ('9606', 'Species') :: ['women', 'Women'] @entity650 :: ('3569', 'Gene') :: ['IL-6', 'interleukin-6'] @entity3152 :: ('MESH:D007752', 'Disease') :: ['preterm labor'] @entity10116 :: ('3484', 'Gene') :: ['insulin-like growth factor-binding protein-1', 'IGFBP-1'] @entity2286 :: ('12211', 'Species') :: ['PPV']
@entity650 :: (3569,Gene) :: ['interleukin-6']
