OBJECTIVES: Breast cancer-related @entity4269 (BCRL) represents a major complication of @entity0 treatment, impacting the quality of life for @entity0 survivors that develop it. The purpose of this review is to evaluate the literature surrounding BCRL treatment modalities to guide clinicians regarding risk-stratified treatment options. METHODS: A review of studies over a 10-year period (January 2006 to February 2016) was performed. Noninvasive strategies evaluated included compression therapy, manual lymphatic drainage, and @entity34 ( @entity34 ). Invasive modalities evaluated included liposuction and lymphatic bypass/lymph node transfer (LNT). Our search yielded 149 initial results with 45 studies included. RESULTS: A number of prospective studies have found that @entity34 is associated with @entity353 in the affected limb as well as improved quality of life, particularly in @entity1 with early stage BCRL. With regards to invasive treatment options, data support that lymphatic bypass and LNT are associated with symptomatic and physiologic improvements, particularly in @entity1 with more advanced BCRL. In addition, a small number of studies suggest that liposuction may be an efficacious and safe treatment for moderate to severe BCRL. CONCLUSIONS: @entity34 is an effective treatment modality for early stage BCRL. For more advanced BCRL, LNT has demonstrated efficacy. Further study is required with respect to comparing BCRL treatment modalities.

A Review of Treatment for XXXX : Paradigms for Clinical Practice.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity353 :: ('MESH:D015431', 'Disease') :: ['volume reduction'] @entity4269 :: ('MESH:D008209', 'Disease') :: ['lymphedema'] @entity34 :: ('MESH:D016609', 'Disease') :: ['CDT', 'complex decongestive therapy']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Cancer-Related Lymphedema']
