UNASSIGNED: Objective Insulin degludec (IDeg), a new long-acting basal insulin, and FlexTouch, a new injection device, recently became available in Japan. The efficacy and usefulness of IDeg and FlexTouch, compared with insulin glargine or detemir, were assessed in @entity1 with @entity6 . Methods We performed an open-label longitudinal trial in 20 @entity1 . After informed consent was obtained, all subjects recorded their self-monitoring data of the blood @entity413 (BG) level; thereafter, basal insulin was replaced by an IDeg-prefilled FlexTouch with the same dose and duration of time (2 weeks). After using FlexTouch, the @entity1 were provided a device-specific questionnaire. Results The @entity1 were divided into two groups according to the dose of basal insulin (>= 10 U and <10 U). Although the mean fasting BG levels were unchanged, the mean BG levels before basal insulin injection and its standard deviation were significantly reduced after switching to IDeg in the @entity1 receiving a higher dose of basal insulin (mean BG before basal insulin injection: 164 to 144 mg/dL, p=0.002; mean standard deviation: 32 to 22, p=0.031); however, this difference was not observed in the @entity1 receiving a lower dose. The @entity1 with a shorter duration of @entity6 and a single injection of insulin preferred FlexTouch compared with conventional insulin devices. Conclusion Replacing basal insulin with IDeg is useful for the stable and accurate control of blood @entity413 levels in type 2 @entity6 for those receiving a higher dose of basal insulin. Furthermore, the @entity1 with a shorter duration of @entity6 and a single insulin injection preferred FlexTouch.

An Open-label Longitudinal Study on the Efficacy of Switching from Insulin Glargine or Detemir to XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity6 :: ('MESH:D003920', 'Disease') :: ['type 2 diabetes mellitus', 'diabetes']
@entity6 :: (MESH:D003920,Disease) :: ['Degludec in Type 2 Diabetes Mellitus']
