BACKGROUND: Potential associations between dietary glycemic index (GI) and glycemic load (GL) with @entity74 remain uncertain. OBJECTIVE: We investigated the relations of dietary GI and GL with @entity458 , @entity148 , and @entity308 . DESIGN: A total of 3363 nonacademic members of the staff of Isfahan University of Medical Sciences were included in this cross-sectional study. GI and GL were assessed by using a validated, self-administered, dish-based, semiquantitative food-frequency questionnaire. @entity148 and @entity308 Scale and General Health Questionnaire-12 were used to assess @entity148 , @entity308 , and @entity458 . RESULTS: After control for potential confounders, individuals in the top tertile of GI had greater odds of @entity308 (OR: 1.44; 95% CI: 1.03, 2.02; P-trend = 0.03) and a trend for greater odds of @entity148 (OR: 1.52; 95% CI: 0.97, 2.38; P trend = 0.06) compared with those in the first tertile. Higher GL values were linked to lower odds for @entity146 (OR: 0.66; 95% CI: 0.49, 0.90; P-trend = 0.009), @entity308 (OR: 0.69; 95% CI: 0.51, 0.93; P-trend = 0.02), and @entity458 (OR: 0.67; 95% CI: 0.48, 0.92; P-trend = 0.01). Significant interactions were observed between GI and sex for @entity308 (P = 0.01) and @entity458 (P = 0.046) in the crude model. In stratified analyses by sex, after control for potential confounders, a greater GI was linked to a higher odds of @entity308 (OR: 1.52; 95% CI: 1.20, 1.94; P-trend = 0.001) and @entity458 (OR: 1.66; 95% CI: 1.28, 2.14; P-trend = 0.001) in @entity1 but not in @entity1 . CONCLUSION: Our findings support a direct link between the odds of @entity308 and dietary GI but inverse associations between GL and @entity146 , @entity308 , and @entity458 . This trial was registered at clinicaltrials.gov as NCT02362113.

Glycemic index, glycemic load, and common XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'men'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression', 'depression'] @entity146 :: ('MESH:D001523', 'Disease') :: ['mental disorders'] @entity458 :: ('MESH:D020018', 'Disease') :: ['psychological distress'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety', 'Validated Iranian versions of the Hospital Anxiety'] @entity74 :: ('MESH:D030342', 'Disease') :: ['psychological disorders']
@entity74 :: (MESH:D030342,Disease) :: ['psychological disorders']
