OBJECTIVES: The effectiveness of sustained acoustic medicine to alleviate @entity158 and improve function in subjects with @entity924 was evaluated through a level IV case series study. Subjects were trained to self-apply the wearable, long-duration, low-intensity ultrasonic device on their affected body part at home for 4  hours a day, at least 5 times per week over 6 weeks. Twenty-five subjects with clinician-diagnosed @entity924 of the elbow (medial or lateral epicondyle) or Achilles tendon were enrolled. METHODS: @entity158 measurements were recorded before, during, and after daily intervention using an 11-point numeric rating scale (NRS). Function of the injured limb was assessed biweekly using dynamometry. Repeated measures ANOVAs and paired-samples t-tests were used to examine the effect of treatment over time. RESULTS: Among subjects with elbow @entity924 (n  =  20), a 3.94      2.15 point @entity158 (p  =  0.002) was observed over the 6-week study and a 2.83      5.52  kg improvement in grip strength (p  =  0.04) was observed over the first two weeks. In addition, a significant @entity158 was observed within the 4-h treatment sessions (p  <  0.001). Among 5 subjects with @entity924 , a @entity158 and improvement in strength was also observed. CONCLUSIONS: Daily multi-hour ultrasonic therapy was associated with improved @entity158 and increased function in subjects with chronic @entity1796 . This trial showed the safety and feasibility of self-administration of sustained acoustic medicine, and suggests that this therapy may be clinically beneficial in the treatment of @entity924 . A randomized controlled trial appears warranted to more definitively investigate the therapeutic potential of this treatment modality. Registered at www.ClinicalTrials.gov , NCT02466308.

Sustained acoustic medicine: wearable, long duration ultrasonic therapy for the treatment of XXXX .

@entity924 :: ('MESH:D052256', 'Disease') :: ['tendinopathies of the elbow and Achilles tendon', 'tendinopathy', 'Achilles tendinopathy', 'elbow or Achilles tendinopathy'] @entity1796 :: ('MESH:D013708', 'Disease') :: ['tendon injuries'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'reduction in pain', 'pain']
@entity924 :: (MESH:D052256,Disease) :: ['tendinopathy']
