PURPOSE: To investigate the efficacy of the Amsler grid test in detecting central @entity227 ( @entity227 ) defects in @entity726 . DESIGN: Prospective, cross-sectional study. @entity1 : @entity1 with @entity726 with reliable Humphrey 10-2 Swedish Interactive Threshold Algorithm standard @entity227 on the date of enrollment or within the previous 3 months. METHODS: Amsler grid tests were performed for each eye and were considered "abnormal" if there was any perceived @entity1019 with missing or blurry grid lines within the central 10 degrees ("Amsler grid @entity1019 "). An abnormal 10-2 @entity227 was defined as >= 3 adjacent points at P < 0.01 with at least 1 point at P < 0.005 in the same hemifield on the pattern deviation plot. Sensitivity, specificity, and positive and negative predictive values of the Amsler grid @entity1019 area were calculated with the 10-2 @entity227 as the clinical reference standard. Among eyes with an abnormal 10-2 @entity227 , regression analyses were performed between the Amsler grid @entity1019 area and the 10-2 @entity227 parameters ( @entity5494 [ @entity5494 ], @entity1019 extent [number of test points with P < 0.01 in total deviation map] and @entity1019 mean depth [mean sensitivity of test points with P < 0.01 in total deviation map]). MAIN OUTCOME MEASURES: Sensitivity, specificity, and positive and negative predictive values of the Amsler grid @entity1019 area. RESULTS: A total of 106 eyes (53 @entity1 ) were included (mean    standard deviation age, 24-2 @entity5494 and 10-2 @entity5494  = 66  12 years,  -9.61  8.64 decibels [dB] and  -9.75  9.00 dB, respectively). Sensitivity, specificity, and positive and negative predictive values of the Amsler grid test were 68%, 92%, 97%, and 46%, respectively. Sensitivity was 40% in eyes with 10-2 @entity5494 better than  -6 dB, 58% in eyes with 10-2 @entity5494 between  -12 and  -6 dB, and 92% in eyes with 10-2 @entity5494 worse than  -12 dB. The area under the receiver operating characteristic curve of the Amsler grid @entity1019 area was 0.810 (95% confidence interval, 0.723-0.880, P < 0.001). The Amsler grid @entity1019 area had the strongest relationship with 10-2 @entity5494 (quadratic R(2)=0.681), followed by 10-2 @entity1019 extent (quadratic R(2)=0.611) and 10-2 @entity1019 mean depth (quadratic R(2)=0.299) (all P < 0.001). CONCLUSIONS: The Amsler grid can be used to screen for moderate to severe central @entity1018 from @entity726 .

Efficacy of the Amsler Grid Test in Evaluating Glaucomatous Central XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PARTICIPANTS'] @entity1018 :: ('MESH:D054062', 'Disease') :: ['vision loss'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual field', 'VF'] @entity5494 :: ('MESH:D010262', 'Disease') :: ['mean deviation', 'MD'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity1019 :: ('MESH:D012607', 'Disease') :: ['scotoma']
@entity227 :: (MESH:D014786,Disease) :: ['Visual Field Defects']
