INTRODUCTION: We studied @entity2247 immunohistochemical staining intensity both in prostatic biopsy and surgical samples of @entity1 with @entity263 to determine if it might provide prognostic information for the decision of re-biopsy indication. MATERIALS AND METHODS: 28 @entity1 undergone radical prostatectomy whose final pathologic examination revealed @entity263 were included in the study. 12 @entity1 with BPH in their pathological examination of both prostatic biopsy and open prostatectomy were considered as a control group. Intensity of @entity2247 receptor was examined with immunohistochemical staining according to standard techniques. RESULTS: Positive @entity2247 receptor staining was obtained 89.3% of biopsy samples and 93% of surgical samples in all @entity5 @entity1 . The rate of agreement in @entity2247 receptor staining of biopsy samples and radical prostatectomy samples was 76% in same @entity1 (p=0,54). Similarly, the @entity2247 receptor levels in biopsy specimens of @entity1 with BPH open surgery compared with samples of the agreement still rate was 41%( p=0.41). @entity263 exchanging @entity2247 receptor levels in @entity1 with biopsy specimens in @entity1 with BPH were found significantly more (p=0,008). CONCLUSION: Our this study, the feasibility of presence of @entity2247 receptor staining in biopsy samples was shown. We have also demonstrated that @entity2247 staining intensity was higher in prostatic biopsy samples of @entity1 with @entity263 than @entity1 with BPH. This leads a conclusion that, higher @entity2247 expression levels in biopsy specimens may be used to decide re-biopsy in borderline preoperative PSA levels as well as in the cases with suspicious pathological findings for @entity5 .

Predictive value of Cyclooxygenase-2 over expression for identifying XXXX from benign prostatic hyperplasia in prostate biopsy specimens.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2247 :: ('4513', 'Gene') :: ['Cox-2'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostatic adenocarcinoma', 'prostatic cancer', 'prostate cancer', 'Prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
