BACKGROUND: @entity24428 ( @entity24428 ) is a rare and aggressive @entity5 of infancy and childhood. It is associated with the development of @entity16970 , a life-threatening consumptive @entity882 . We report an interesting case of a massive periorbital congenital @entity24428 in a neonate to raise awareness of this aggressive diagnosis. METHODS: A male neonate presented with a large congenital mass of the lower eyelid. To prevent development of @entity4457 , this mass was surgically excised on the sixth day of life. RESULTS: Histologic investigation demonstrated spindle-shaped endothelial cells with surrounding crescentic vessels, which were GLUT-1 receptor-negative and D2-40 receptor-positive, consistent with @entity24428 . Surgical excision of the periorbital @entity24428 successfully cleared the neonate's @entity227 . At 1 year of follow-up, there was no evidence of @entity5 recurrence, and visual development was progressing normally. A pleasing surgical result was achieved without periorbital distortion. CONCLUSIONS: Pediatric @entity5 have historically been wrought with diagnostic @entity911 . With recent advances in immunohistochemistry, this previously uncharacterized group of @entity5 has been differentiated into multiple distinct clinical entities. Accurate and timely diagnosis is paramount because these @entity5 vary greatly in their clinical behavior, prognosis, and recommended treatment. Surgical excision is preferred and necessary in a neonate with @entity227 to prevent @entity4457 and irreversible @entity1939 .

Massive XXXX of the eyelid in a neonate.

@entity227 :: ('MESH:D014786', 'Disease') :: ['visual access obstruction', 'visual axis'] @entity24428 :: ('MESH:C537007', 'Disease') :: ['Kaposiform hemangioendothelioma', 'KHE'] @entity882 :: ('MESH:D013921', 'Disease') :: ['thrombocytopenia'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'vascular tumor', 'vascular tumors', 'tumors'] @entity16970 :: ('MESH:D059885', 'Disease') :: ['Kasabach-Merritt syndrome'] @entity1939 :: ('MESH:D001766', 'Disease') :: ['blindness'] @entity911 :: ('MESH:D003221', 'Disease') :: ['confusion'] @entity4457 :: ('MESH:D000550', 'Disease') :: ['amblyopia']
@entity24428 :: (MESH:C537007,Disease) :: ['congenital kaposiform hemangioendothelioma']
