@entity2783 is an uncommon @entity558 which usually arises secondary to @entity281 or @entity130 to the eye. It is rare to find significant deposits of amyloid involving the conjunctiva alone in the absence of a known antecedent infective, traumatic or @entity74 . We report three @entity1 with primary localised @entity2783 . Each @entity1 presented with a @entity4 in the lower fornix; in two this gradually extended to involve the bulbar and palpebral conjunctiva of both eyes with friable yellow deposits. Detailed clinical photographs illustrate the specific features of the disease. None of the @entity1 had previous ocular pathology and @entity1800 of the conjunctiva were negative. There were no signs of @entity32 . Conjunctival biopsies in each case showed large amorphous nodular deposits of @entity10543 . Extensive systemic investigations including serum and urinary protein immunoelectrophoresis were normal. Follow-up ranged from 2 to 15 years after presentation. Treatment was symptomatic. As the typical features of @entity2783 present late in the course of conjunctival disease a diagnostic biopsy is often delayed. Once there is histopathological verification plasma cell disease must be excluded, although if the amyloid is limited to the conjunctiva systemic involvement is unlikely.

Primary (localised non-familial) XXXX : three case reports.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity558 :: ('MESH:C536528', 'Disease') :: ['condition'] @entity2783 :: ('MESH:D000686', 'Disease') :: ['amyloidosis', 'Conjunctival amyloidosis', 'conjunctival amyloidosis'] @entity4 :: ('MESH:D004487', 'Disease') :: ['painless swelling'] @entity281 :: ('MESH:D007239', 'Disease') :: ['chronic infection'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['bacterial, viral and fungal cultures'] @entity10543 :: ('MESH:D017772', 'Disease') :: ['amyloid within the substantia propria'] @entity74 :: ('MESH:D030342', 'Disease') :: ['hereditofamilial disorder'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity2783 :: (MESH:D000686,Disease) :: ['conjunctival amyloidosis']
