OBJECTIVE: The goal of this study was to examine the relationship between shift work and cardiovascular risk factors in a cross sectional survey. MATERIAL AND METHODS: 2 610 @entity1 of the PRIME study, aged 50-60 years, residing in Haute-Garonne (France) and selected from health centers and various firms were screened. @entity62 , retired and disabled @entity1 at the time of the study were excluded so the analysis was performed on a sample of 1,341 subjects. Work was categorized as day work (n = 1,161) and three types of shift work: 2 x 8 (n = 108), 3 x 8 (n = 41) and night (n = 31). A comparison of cardiovascular risk factors was performed in the different types of work. RESULTS: Univariate analysis showed that systolic blood pressure was significantly higher among 2 x 8 workers (132.7 +/- 17.4 mmHg) than in other shift workers and day workers (126.9 +/- 15.1 mmHg). The same difference was observed for diastolic blood pressure. Plasma @entity1674 were significantly higher among night workers (1.60 +/- 0.76 g/l) than among day workers (1.29 +/- 0.81 g/L). Logistic regression analysis showed that the risk of @entity101 , defined as systolic (> or = 140 mmHg) and diastolic (> or = 90 mmHg) blood pressure and/or antihypertensive drug, was 2 times higher among 2 x 8 shift workers (OR: 2.14, 95% CI [1.42-3.23]) than among day workers after adjustment for BMI, @entity167 and @entity286 consumption and plasma @entity412 levels. The same result (OR: 1.99, 95% CI [1.28-3.12] was obtained with a different @entity101 (systolic > or = 160 mmHg and/or diastolic > or = 95 mmHg blood pressure and/or antihypertensive drug). Among night workers the risk of @entity1674 > 2 g/L was higher (OR: 2.52, 95% CI [1.06-6.01] than among day workers. The risk of both @entity101 (140/90 mmHg) and @entity2298 in comparison to day workers was (OR: 2.01, 95% CI [1.33-3.03]) and (OR: 2.44, 95% CI [1.14-5.21]) for 2 x 8 shift workers and night shift workers respectively. CONCLUSION: The results of this study, putting into evidence a relationship between shift work, @entity101 and high level of @entity1674 , justify a careful screening by occupational physicians of cardiovascular risk factors among shift workers.

[Cardiovascular risk factors and shift work in XXXX living in Haute-Garonne, France].

@entity1 :: ('9606', 'Species') :: ['men'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity2298 :: ('MESH:D015228', 'Disease') :: ['hypertriglyceridemia'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'definition of hypertension'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity62 :: ('MESH:D056784', 'Disease') :: ['White-collar workers']
@entity1 :: (9606,Species) :: ['men']
