BACKGROUND: Low molecular weight heparin can be administered by the subcutaneous route and has a stable and prolonged antithrombotic effect. These features have prompted clinical essays about its use as an alternative to unfractionated heparin in the treatment of @entity1459 . AIM: To compare the clinical effects of low molecular weight heparin and unfractionated conventional heparin in @entity1 with @entity1459 or non Q @entity1188 . @entity1 AND METHODS: Seventy @entity1 (47 male) admitted to the hospital with the diagnosis of @entity1459 or non Q @entity583 were randomly assigned to receive unfractionated intravenous heparin or subcutaneous low molecular weight heparin bid. All received @entity117 p.o. and i.v. @entity1242 . The incidence of recurrent angina, @entity583 or a need for emergency surgical revascularization during hospital stay were assessed in both groups. RESULTS: Compared to @entity1 with low molecular weight heparin, @entity1 receiving unfractionated heparin had a higher incidence of recurrent resting angina (23 and 47.5% respectively, p < 0.04) and higher need for emergency surgical revascularization (3.3 and 17.5% respectively, p < 0.06). @entity1 treated with unfractionated conventional heparin had a 3 times higher risk of having an adverse cardiovascular event than @entity1 receiving low molecular weight heparin (O.R. 0.33, confidence intervals 0.11-0.58). CONCLUSIONS: Low molecular weight heparin is superior to unfractionated conventional heparin in the treatment of @entity1459 and non Q @entity583 .

[Comparison of low-molecular-weight heparin and unfractionated heparin in the treatment of XXXX ].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity1242 :: ('MESH:D005996', 'Chemical') :: ['nitroglycerin'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity1459 :: ('MESH:D000789', 'Disease') :: ['unstable angina'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarction'] @entity583 :: ('MESH:D009203', 'Disease') :: ['acute myocardial infarction']
@entity1459 :: (MESH:D000789,Disease) :: ['unstable angina']
