OBJECTIVE: To perform a systematic literature review of the diagnostic and prognostic value of magnetic resonance imaging (MRI) and ultrasound (US) in @entity1 with undifferentiated peripheral @entity625 (UPIA), and to assess if MRI and US should be done at baseline and repeated, and if so, at what interval. METHODS: Medline, Embase, the Cochrane Library, and abstracts presented at the 2007 and 2008 meetings of the American College of Rheumatology and European League Against @entity627 meetings were searched for diagnostic and prognostic studies of any duration examining the ability of MRI/US to predict outcome of @entity1 with UPIA. Sensitivity, specificity, predictive values, and positive/negative likelihood ratios (LR+/LR-) were calculated. When available, odds ratios were extracted. Quality was appraised using validated scales. RESULTS: Regarding MRI, 11 out of 2595 screened references were included: 2 described pure undifferentiated @entity625 (UA) populations and 9, mixed populations. Bone @entity4 (LR+ 4.5) and combination of a distinct @entity603 and erosion pattern (LR+ 4.8) increased probability of developing @entity309 ( @entity309 ). Absence of @entity603 (LR- 0.2) and absence of a distinct @entity603 pattern (LR- 0) decreased probability of developing @entity309 . Regarding US, 2 out of 2111 references were included, both mixed populations; no data could be extrapolated for UPIA. CONCLUSION: MRI bone @entity4 and @entity603 and erosion pattern seem useful in predicting development of @entity309 from UPIA. The value of US in UPIA remains to be determined. The absence of @entity603 seems useful in excluding development of @entity309 . No data were found about the value of repeating MRI/US. Studies evaluating MRI/US in UPIA are scarce, but current knowledge strongly encourages further testing in UA.

The value of magnetic resonance imaging and ultrasound in undifferentiated XXXX : a systematic review.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity627 :: ('MESH:D012216', 'Disease') :: ['Rheumatism'] @entity625 :: ('MESH:D001168', 'Disease') :: ['inflammatory arthritis', 'arthritis'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity603 :: ('MESH:D013585', 'Disease') :: ['synovitis', 'MRI synovitis', 'combined synovitis'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA']
@entity625 :: (MESH:D001168,Disease) :: ['arthritis']
