A review of reports on metastatic @entity5 published from 1903 to 1998 in Japan revealed 128 @entity1 , 74 males, 52 females and 2 whose sex was not recorded. The average age was 44.8 years, but varied depending on the @entity5 . Since 1980, metastatic @entity5 have increased in Japan, especially those from the lung, liver and adrenal gland, while @entity3 from the stomach has decreased slightly. @entity3 from the breast is still common. Most metastatic @entity5 were from the lung, followed, in order, by breast, liver, adrenal gland and stomach. Males had four times as many metastatic @entity5 from @entity2 than did females; only females had @entity3 from @entity0 ; almost 90% of @entity3 from @entity157 were in males; @entity3 from @entity703 was 2-3 times more common in males than in females. @entity3 from the liver and stomach is seen more frequently in Japan than in the United States and Europe. Ocular signs due to orbital @entity3 from @entity157 , @entity521 and @entity356 were apt to appear earlier than the signs of the @entity75 . @entity3 to the orbit were frequently bilateral in @entity1 with @entity521 and @entity706 . Specific ocular signs such as ecchymosis and @entity548 were seen in orbital @entity3 from @entity521 and @entity4797 , while @entity3856 was characteristic of @entity706 . Orbital @entity3 was very rare in @entity1 with @entity189 , ovaries, bladder, pancreas, @entity694 in both Japan, the United States and Europe.

Metastatic XXXX in Japan: a review of the literature.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity706 :: ('MESH:D008223', 'Disease') :: ['malignant lymphoma'] @entity548 :: ('MESH:D006470', 'Disease') :: ['conjunctival hemorrhages'] @entity5 :: ('MESH:D009369', 'Disease') :: ['orbital tumors', 'primary tumor'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesion'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma of the uterus'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'Metastasis', 'metastases', 'Metastases'] @entity521 :: ('MESH:D009447', 'Disease') :: ['neuroblastoma'] @entity4797 :: ('MESH:D018239', 'Disease') :: ['seminoma'] @entity157 :: ('MESH:D006528', 'Disease') :: ['hepatoma'] @entity3856 :: ('MESH:D058447', 'Disease') :: ['ocular pain'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon or rectum'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['orbital tumors']
