@entity7 ( @entity7 ) and @entity2533 ( @entity2533 ) play an important role in angiogenesis. We wanted to determine if concentrations of growth factors in the coronary sinus (CS) and @entity13678 ( @entity13678 ) are higher in @entity453 @entity1 with total occlusions than in those with partial occlusions. Fifty-one @entity1 scheduled for coronary artery angiography were evaluated for possible recruitment. A 6F Goodale-Lubin catheter was used to collect blood from the CS and @entity13678 . Data for all but four @entity1 were gathered successfully, leaving 47 study @entity1 . The reviewer was blinded to growth factor data when interpreting coronary angiographic findings. Of the 47 enrolled @entity1 , 32 had at least one diseased vessel, seven of whom had at least one major total @entity1563 . In all 32 @entity1 , the concentrations of @entity7 in the CS were higher than those in the @entity13678 (31.5 +/- 2.7 vs 27.1 +/- 1.8 pg/mL; p = 0.005). @entity1 with total occlusions had higher @entity7 concentrations in the CS than those with non-total occlusions (38.9 +/- 8.0 vs 29.5 +/- 2.6 pg/mL; p = 0.037). The differences in @entity2533 in the two groups were not statistically significant. The higher CS @entity7 concentrations in @entity1 with total occlusion indicate that @entity7 may play a part in the development of angiogenesis.

Effects of total coronary artery occlusion on vascular endothieial growth factor and XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity13678 :: ('MESH:D064752', 'Disease') :: ['RA', 'right atrium'] @entity7 :: ('7422', 'Gene') :: ['VEGF', 'Vascular endothelial growth factor'] @entity1563 :: ('MESH:D054059', 'Disease') :: ['epicardial coronary occlusion'] @entity2533 :: ('7040', 'Gene') :: ['TGF-beta1', 'transforming growth factor beta'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease']
@entity2533 :: (7040,Gene) :: ['transforming growth factor beta']
