@entity298 ( @entity298 ) @entity1 lose significant quantities of protein and albumin during the dialysis procedure. The losses are greater in high transporters. The aim of the present study was to investigate the relationship between peritoneal membrane transport characteristics and protein losses. We studied 33 @entity298 @entity1 [14 @entity1 , 19 @entity1 ; mean age: 53.5 years (range: 21-80 years)]. Fourteen @entity1 had @entity6 , and 22 were on automated @entity298 . Dialysis adequacy was good, with a mean Kt/V of 2.63 (range: 1.51-4.89). @entity1 underwent a standard peritoneal equilibration test (PET). In addition, dialysate albumin ( @entity2313 ) and protein (Pro) were measured at 0, 1, 2, and 4 hours, after lack of interference from unspent dialysate was ensured. Of the 33 @entity1 , 23 were high or high-average transporters [based on 4-hour dialysate-to-plasma ratio of @entity1011 (D/PCr > or = 0.65)]. Protein losses owing to @entity298 ranged from 3.5 g/day to 13.2 g/day (median: 5.9 g/day), of which 1.9-7.14 g/day (median: 3.21 g/day) was albumin. The 4-hour D/PCr correlated with the 4-hour D/PAlb (r = 0.62, p < 0.01), and 4-hour D/PPro (r = 0.63, p < 0.01). This finding persisted after correction for volume, indicating that it was not simply a concentration effect. The 4-hour D/PAlb and 4-hour D/PPro also correlated with the 24-hour @entity298 albumin and protein losses. These results suggest a strong association between D/PCr and D/P for proteins. This observation is consistent with the increased protein losses through @entity298 in high transporters and may be related to the inferior outcomes in this group.

The relationship between dialysate protein loss and membrane transport status in peritoneal dialysis XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity2313 :: ('213', 'Gene') :: ['Alb'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity298 :: ('MESH:D010538', 'Disease') :: ['Peritoneal dialysis', 'PD']
@entity1 :: (9606,Species) :: ['patients']
