Background. The plant Cornus mas L. (cornelian cherry) is traditionally used as an antidiabetic supplement; however, there is no related clinical trial. In this study, we evaluated the effects of the fruit extract of this plant on biomarkers of glycemic control in adult @entity1 with @entity164 2 @entity6 . Methods. Sixty @entity1 with @entity164 2 @entity6 were randomly assigned to two groups to receive either the extract or placebo capsules (2 capsules twice daily) for 6 weeks. Each drug capsule contained 150 mg of @entity4211 . Fasting plasma levels of @entity413 , @entity2690 , HgbA1C, and @entity412 as well as 2-hour postprandial @entity413 level (2Hpp) were measured before and after the intervention and finally the mean values were compared between groups. Results. After 6 weeks of intervention, significant increase in @entity2690 level (1.13    1.90 versus -0.643    1.82, P < 0.05) as well as decrease in HgbA1C (-0.24    0.429 versus 0.023    0.225, P < 0.05) and TG (-23.66    55.40 versus 2.83    15.71, P < 0.05) levels was observed in drug group compared to placebo. Conclusion. Daily consumption of the fruit extract of Cornus mas L. improves glycemic control by increasing @entity2690 level and reduces TG serum level in @entity164 2 @entity6 adult @entity1 .

Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and XXXX Level in Type 2 Diabetic Adult @entity1 : A Randomized Double-Blind Placebo-Controlled Clinical Trial.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic', 'diabetes'] @entity2690 :: ('3630', 'Gene') :: ['insulin'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity164 :: ('MESH:D017827', 'Disease') :: ['type'] @entity4211 :: ('MESH:D000872', 'Chemical') :: ['anthocyanins'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity2690 :: (3630,Gene) :: ['Insulin']
