BACKGROUND: @entity1 who are exclusively breastfed receive natural protection against some infectious agents. This study examined whether there was protective effect of exclusive breastfeeding on the occurrence of hand, foot @entity3137 , which was an emerging @entity166 among @entity1 in China. METHODS: A community-based case-control study was carried out among @entity1 age 4  years or younger in Guangdong Province, China. Cases were newly diagnosed hand, foot @entity3137 . Controls were randomly sampled from healthy @entity1 from the nearby village. Unconditional logistic regression model was used to estimate the odds ratio (OR) for exclusive breastfeeding after adjusting for potential confounding factors. RESULTS: A total of 316 cases and 566 controls were included in the analysis. Significantly beneficial effect of exclusive breastfeeding during the first 6  months was observed for hand, foot @entity3137 occurrence. The overall OR was 0.63 (95% CI: 0.47-0.85) for exclusive breastfeeding compared with mixed feeding type. The age-specific analyses indicated that the protective effect persisted till the age of 28  months. CONCLUSIONS: This study suggests that exclusive breastfeeding might have protective effect against @entity281 among the @entity1 within 28  months of age.

Protective effect of exclusive breastfeeding against hand, foot XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Infants'] @entity281 :: ('MESH:D007239', 'Disease') :: ['HFMD infection'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious disease'] @entity3137 :: ('MESH:D009059', 'Disease') :: ['and mouth disease']
@entity3137 :: (MESH:D009059,Disease) :: ['and mouth disease']
