UNASSIGNED: @entity65 ( @entity65 ) are considered the leading cause of morbidity and mortality from @entity102 in the world. In addition, about 20% of first and recurrent acute @entity583 ( @entity583 ) are silent. In this context, subclinical @entity731 culminates in evident @entity65 , through the evolution of early risk factors such as @entity1007 , @entity2298 and others. The main problem in @entity65 is related to the long-time between the start of the subclinical @entity731 and the manifestation of the disease. The identification of subjects at risk of such events is obviously substantial, since identification leads to implementation and compliance with effective preventive measures that reduce such risk. In this sense, this review demonstrates biomarkers as an alternative to early detection of subclinical @entity731 . One of the proposed biomarkers is the @entity63 -modified albumin (IMA), being considered a promising biochemical biomarker for @entity731 conditions. Another marker that is gaining strength and is associated with the IMA are the advanced oxidation protein products (AOPP), its measurement provides information on the level of exposure to potentially harmful changes to proteins and metabolic control. And last but not least we have @entity842 as an early marker mainly related to @entity409 . In this review also is evidenced the use of the Campomanesia xanthocarpa, a plant native to southern region from Brazil extensively used as complementary and alternative medicine, and natural products to reduce protein oxidation and improve the availability of @entity842 and consequently vascular function, reducing the risk for development of @entity65 .

Biomarkers of Subclinical XXXX and Natural Products as Complementary Alternative Medicine.

@entity2298 :: ('MESH:D015228', 'Disease') :: ['hypertriglyceridemia'] @entity1007 :: ('MESH:D006937', 'Disease') :: ['hypercholesterolemia'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic', 'atherosclerosis'] @entity63 :: ('MESH:D007511', 'Disease') :: ['Ischemia'] @entity409 :: ('MESH:D008107', 'Disease') :: ['endothelial dysfunction'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic diseases'] @entity842 :: ('MESH:D009569', 'Chemical') :: ['nitric oxide'] @entity583 :: ('MESH:D009203', 'Disease') :: ['MI', 'myocardial infarctions'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'Cardiovascular diseases']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerosis']
