Optimal fluid management to reduce @entity190 during donor hepatectomy is important for maximizing donor safety. @entity2656 can induce osmotic diuresis, helping prevent increased intravascular volume status. We therefore evaluated the effect of high @entity64 volume variation ( @entity6355 ) method by @entity2656 administration and fluid restriction on @entity190 during donor hepatectomy.In this prospective study, 64 donors scheduled for donor right hepatectomy were included and allocated into 2 groups. In group A, the @entity6355 value of each @entity1 was maintained at 10% to 20% during hepatic resection with 0.5g/kg @entity2656 administration and fluid restriction at a rate of 2 to 4mL/kg/h. In group B, the @entity6355 value was maintained at <10% by fluid administration at a rate of 6 to 10mL/kg/h without diuretic administration during surgery. Intraoperative @entity190 was estimated by the loss of red cell mass. Surgeon satisfaction scores and postoperative outcomes, including @entity810 , abnormal chest radiographic findings, and hospital stay duration, were also assessed. @entity6355 during hepatectomy was significantly higher in group A than in group B (11.0  1.7 vs 6.5  1.1, P<0.001). The red cell mass loss was significantly lower in group A than in group B (145.4  107.6 vs 307.9  110.7mL, P<0.001). Surgeon satisfaction scores were higher in group A than in group B (2.8  0.5 vs 2.0  0.6, P<0.001). The incidence of @entity810 , abnormal chest radiographic findings, and duration of hospital stay did not significantly differ between the 2 groups.Maintenance of high @entity6355 by @entity2656 administration is effective and safe for reducing @entity190 during donor hepatectomy.

High Stroke Volume Variation Method by XXXX Administration Can Decrease Blood Loss During Donor Hepatectomy.

@entity2656 :: ('MESH:D008353', 'Chemical') :: ['Mannitol', 'mannitol'] @entity1 :: ('9606', 'Species') :: ['patient'] @entity6355 :: ('35246', 'Species') :: ['SVV'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute kidney injury']
@entity2656 :: (MESH:D008353,Chemical) :: ['Mannitol']
