PURPOSE: To evaluate the rate of major complications related to percutaneous computed tomography (CT)-guided microwave ablation (MWA) of primary and secondary @entity358 performed at our institution over a 4-year period. METHODS: From May 2010 to September 2014, 70 MWAs were performed on 51 @entity1 . All major intra- and post-procedural complications (as defined by the classification proposed by the Society of Interventional Radiology) were retrospectively analysed. The results were correlated with a systematic review of the available literature on MWA in the lung. RESULTS: Major complications were encountered in 14 out of 70 ablations (20%). Twenty-one separate major complications were encountered (some ablations lead to more than one major complication). One @entity204 occurred within 30 days of ablation, though the relationship to the procedure remains uncertain. Other major complications included: nine pneumothoraces requiring drain insertion (12.9%), four cases of large effusion requiring drainage (5.7%), two cases of significant @entity548 altering clinical management (2.9%), two infections (2.9%), one case of mechanical failure (1.4%), one chest wall burn (1.4%) and one case of pleural seeding (1.4%). Major complications were much more likely to occur if the nodule was located within 7   mm from the pleura. CONCLUSION: MWA of @entity5 carries moderate risk; nevertheless, the usually manageable complications should not deter from undertaking a potentially curative therapy for poor surgical candidates.

Major complications of high-energy microwave ablation for percutaneous CT-guided treatment of XXXX : Single-centre experience after 4 years.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['pulmonary haemorrhage'] @entity5 :: ('MESH:D009369', 'Disease') :: ['pulmonary tumours'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung malignancies'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity358 :: (MESH:D008171,Disease) :: ['lung malignancies']
