OBJECTIVE: To evaluate in @entity6 @entity1 with foot ulcers the angiographic findings of @entity8901 and their role as a prognostic determinant for major amputation. RESEARCH DESIGN AND METHODS: From 1993 to 1995, 104 @entity6 inpatients with foot ulcers underwent arteriography on the ulcerated limb. Stenoses in the iliac trunk, the superficial femoral artery, the profunda femoral artery, the popliteal artery, the anterior tibial artery, the posterior tibial artery, and the peroneal artery were scored on the basis of vessel lumen reduction: 0 if stenoses involved a reduction in the vessel lumen of < 50%, 1 if stenoses involved 50 to < 75% reduction, 2 if stenoses involved 75 to < 100% reduction, and 3 if total occlusion was present. The sum of the points assigned to each of these arteries was called the angiographic score. RESULTS: Stenoses causing a vessel lumen reduction > or = 50% were detected in 103 @entity1 (99%). Stenoses were also detected in subjects with palpable foot pulses, ankle-brachial indexes > or = 1, or transcutaneous @entity26 tension > or = 50 mmHg. The risk of major amputation was increased significantly when total occlusion was present in the popliteal and infrapopliteal arteries (chi 2 for trend = 50.57, P < 0.001). No major amputation was carried out in @entity1 with angiographic scores < 10; major amputation was carried out in all the @entity1 with scores > 14. Multivariate analysis indicated a high angiographic score as an independent risk factor for major amputation (odds ratio 2.32, P = 0.001, CI 1.40-3.84). CONCLUSIONS: Angiography permits an exact detection of occlusive @entity455 in subjects with normal results for noninvasive vascular procedures. A score that has a relevant prognostic value for major amputation can be obtained from the evaluation of the extent and diffusion of the stenoses.

Angiographic evaluation of peripheral arterial occlusive disease and its role as a prognostic determinant for major amputation in XXXX subjects with foot ulcers.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity455 :: ('MESH:D014652', 'Disease') :: ['arterial disease'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity8901 :: ('MESH:C564658', 'Disease') :: ['peripheral occlusive arterial disease']
@entity6 :: (MESH:D003920,Disease) :: ['diabetic']
