OBJECTIVE: The aim of this study was to ascertain the early developmental status of @entity1 who have a history of newborn @entity75 . METHODS: A longitudinal follow-up was conducted of a population-based, case-control study of @entity1 born in Western Australia between June 1993 and December 1996. The study included 276 term @entity1 (>/=37 weeks' gestation) with moderate or severe newborn @entity75 and 564 unmatched term control subjects. The Griffiths Mental Development Scales was used to ascertain developmental status and a General Quotient (GQ) score. Outcome measures were the Griffiths developmental subscales, GQ, diagnosis of @entity306 , and mortality. RESULTS: Thirty-four @entity1 and 1 control subject died before reaching assessment. Between June 1994 and December 1999, 195 (81%) eligible @entity1 and 445 (79%) eligible control subjects were assessed. Statistically significant differences were found between @entity1 and control subjects for GQ and all developmental subscales. Overall, 39% of @entity1 had a poor outcome as defined by death, @entity306 , or a significant degree of @entity245 , compared with 2.7% of control subjects. Furthermore, 62% of those with severe @entity75 had a poor outcome compared with 25% of those with moderate @entity75 . @entity1 with a history of @entity410 were 3 times more likely to develop @entity306 than @entity1 without. Overall, 28 (10.1%) of @entity1 have @entity306 . CONCLUSIONS: These data provide important prognostic information regarding survival and serious disability and indicate that newborn @entity75 places @entity1 at significant risk of @entity245 by their second year. These findings also suggest that comprehensive clinical and educational assessments are required to enable appropriate educational provisions as these @entity1 approach school entry.

Early developmental outcomes after newborn XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'infants'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity75 :: ('MESH:D001927', 'Disease') :: ['encephalopathy'] @entity245 :: ('MESH:D002658', 'Disease') :: ['developmental delay'] @entity306 :: ('MESH:D002547', 'Disease') :: ['cerebral palsy']
@entity75 :: (MESH:D001927,Disease) :: ['encephalopathy']
