OBJECTIVES: To evaluate the feasibility and efficacy of @entity5273 ( @entity5273 ) for extra-hepatic portal @entity432 (EHPVO) with recurrent @entity548 (RVB) in @entity1 . METHODS: From November 2005 to December 2013, 28 consecutive paediatric @entity1 with EHPVO treated with @entity5273 for RVB refractory to medical/endoscopic therapy and/or surgical treatment in a tertiary-care centre were followed until last clinical evaluation or @entity204 . The median follow-up time was 36.0 months (range 4.0-106.0 months). RESULTS: Seventeen @entity1 and eleven @entity1 aged 7.1 to 17.9 years (median 12.3 years) weighing 19.0-62.0kg (median 33.5kg) were treated. @entity5273 was successfully placed in 17 of 28 (60.7%) of @entity1 via a transjugular approach alone (n=4), a combined transjugular/transhepatic approach (n=9), or a combined transjugular/transsplenic approach (n=4). @entity409 occurred in 6 of 17 (35.3%) @entity1 . The cumulative 1- and 3-year free-from-variceal-rebleeding rates in @entity5273 success group were higher than those in @entity5273 failure group (75.0% and 67.5% versus 45.5% and 18.2%, respectively, p=0.0075). Compared with the @entity5273 failure group, the improvements in the height-for-age z-scores were greater in the @entity5273 success group (p=0.017). Procedure-related complication occurred in one @entity1 (3.6%), and no episode of post- @entity5273 hepatic @entity75 occurred in any @entity1 . Except one @entity1 in the @entity5273 success group died at 115 post-operative days, all @entity1 were alive. CONCLUSIONS: @entity5273 is feasible and effective in @entity1 with EHPVO and RVB. @entity5273 could represent a less invasive alternative to traditional surgical portosystemic shunting or a valuable treatment option if surgery and endoscopic treatment failed.

Transjugular Intrahepatic Portosystemic Shunt for Extra-Hepatic Portal XXXX in @entity1 .

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient', 'girls', 'boys'] @entity548 :: ('MESH:D006470', 'Disease') :: ['variceal bleeding'] @entity75 :: ('MESH:D001927', 'Disease') :: ['encephalopathy'] @entity5273 :: ('MESH:C562830', 'Disease') :: ['TIPS', 'transjugular intrahepatic portosystemic shunt'] @entity409 :: ('MESH:D008107', 'Disease') :: ['Shunt dysfunction'] @entity432 :: ('MESH:D001157', 'Disease') :: ['venous obstruction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity432 :: (MESH:D001157,Disease) :: ['Venous Obstruction']
