UNASSIGNED: Flexor tendon laceration is a @entity5883 . Timely and correct diagnosis of this defect is an important factor for restoring hand function. Post-operative adhesion is a frequent problem after tendon repair and its prevention is @entity924 . There have been some controversial studies on the positive effect of some materials and substances on prevention of these adhesions. This study aims to evaluate effects of the Heparin in postoperative tendon adhesions. In this clinical trial, 100 @entity1 with laceration of flexor tendons in zone II of the hand were enrolled. The @entity1 were randomly divided into two groups. In the first group, 0.5  cc Heparin (5000  IU/cc) was injected into each tendon ends before tendon repair. In the control group, repair was carried out without any heparin injection. After 3  months the total active range of motion (TAROM), mean extension gap (MEG) and mean flexion gap (MFG) were measured and compared between these two groups. The TAROM and MEGs were not significantly different between two groups; but MFGs were significantly better in Heparin treated group (P   <   0.02). However @entity397 rate was significantly higher in @entity6950 treated group (P   =   0.003). Heparin may improve the tendons function and reduce the postoperative adhesions in zone II of the hand; however there is a significant risk of @entity397 .

Effect of XXXX on Post-Operative Adhesion in Flexor Tendon Surgery of the Hand.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5883 :: ('MESH:D006230', 'Disease') :: ['common hand injury'] @entity924 :: ('MESH:D052256', 'Disease') :: ['difficult in some types of tendon lacerations'] @entity6950 :: ('MESH:D006493', 'Chemical') :: ['heparin'] @entity397 :: ('MESH:D012421', 'Disease') :: ['tendon rupture', 'rupture']
@entity6950 :: (MESH:D006493,Chemical) :: ['Heparin']
