We assessed the influence of current indoor levels of fungi, house dust mite allergen (Der @entity3881 ), and cat allergen (Fel d 1) on sensitization and @entity565 in adults. A total of 485 adults answered a questionnaire and had skin prick tests and lung function tests. Dust and air samples were collected from their bedrooms. The dust was analyzed for Der @entity3881 , Fel d 1, and fungal biomass ( @entity12364 ). Fungal propagules were measured in air samples. Current @entity565 was defined as having wheezed during the past 12 mo plus @entity6587 ( @entity6587 ) to @entity2710 . High exposure to total airborne fungi was associated with increased @entity6587 , but perhaps paradoxically with a lower risk of being sensitized to fungi. @entity12364 levels in floor dust were a risk factor both for being sensitized to fungi and having wheezed within the last year. High Fel d 1 levels in floor dust were found to increase the risk of being sensitized to @entity468 and in beds to increase the risk of current @entity565 . Although Der @entity3881 levels in homes were high, @entity1 exposed to high Der @entity3881 levels in floor dust were less likely to be sensitized to house dust mites or to have wheezed within the past year. Current indoor levels of fungi and Fel d 1, but not Der @entity3881 , influenced sensitization and @entity565 in adults with high dust mite exposure.

Current indoor allergen levels of fungi and XXXX , but not house dust mites, influence allergy and @entity565 in adults with high dust mite exposure.

@entity12364 :: ('MESH:D004875', 'Chemical') :: ['Ergosterol', 'ergosterol'] @entity3881 :: ('1423', 'Gene') :: ['p 1'] @entity1 :: ('9606', 'Species') :: ['people'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity468 :: ('9685', 'Species') :: ['cats'] @entity6587 :: ('MESH:D016535', 'Disease') :: ['BHR', 'bronchial hyperreactivity'] @entity2710 :: ('MESH:D016210', 'Chemical') :: ['methacholine']
@entity468 :: (9685,Species) :: ['cats']
