This retrospective study evaluated outcome with regard to procedure, local control, and survival after curative surgical resection with and without preoperative radiotherapy for local pelvic recurrence. A total of 58 consecutive @entity1 with local pelvic recurrence of @entity5 after previous curative resection for @entity5 were reviewed. Of these, 36 underwent both initial resection and follow-up in our department; the remaining 22 had initial surgery and follow-up elsewhere. Of the 58 @entity1 27 underwent curative re-resection, 9 had palliative resection, and 22 were treated by conservative therapy. Among the 27 @entity1 with curative resection 17 received preoperative radiotherapy (40 Gy) plus surgery and 10 surgery only. No @entity1 were lost to follow-up; median follow-up time was 36.3 months. The overall rate of curative resection was 46.6%: 55.6% in our own follow-up group and 31.8% in the others. With regard to surgical procedure, abdominoperineal resection (APR) with or without sacral resection was standard following previous low anterior resection, and total pelvic exenteration (TPE) with or without sacral resection was common following APR. There was a high incidence of morbidity (71.4%) after TPE. Re-recurrence was observed in 12 (44.4%) after curative re-resection. There was local re-recurrence in 6 (22.2%). The local re-recurrence rate was 11.8% (n = 2) with radiotherapy plus surgery, and 40.0% (n = 4) with surgery alone. The estimated 5-year survival following curative re-resection was 45.6% (61.2% with radiotherapy plus surgery, 29.6% with surgery alone). Both survival and local control with radiotherapy plus surgery tended to be better than with surgery alone. Thus, in selected @entity1 pelvic local recurrence of @entity5 can be re-resected curably by APR or TPE (with or without sacral resection) combined with preoperative radiotherapy.

Surgery for local pelvic recurrence after resection of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['rectal cancer', 'primary tumors']
@entity5 :: (MESH:D009369,Disease) :: ['rectal cancer']
