AIM: Haemolysis has a major impact on @entity1 safety as the need for a replacement specimen increases the risk of @entity130 , delays test results and extends the duration of hospital stays. Consistency of haemolysis detection and reporting can facilitate the generation of benchmark data used to develop quality practices to monitor and reduce this leading cause of pre-analytical laboratory error. This review aims to investigate current methods of haemolysis detection and reporting. METHOD: Due to known heterogeneity and @entity44 of the research field, a scoping search was conducted using PUBMED, Embase, Medline and CINAHL. Articles published between 2000 and 2014 that reported haemolysis rates in specimens from the general population were included. RESULTS: Of the 50 studies that met the inclusion criteria, 20 detected haemolysis using the @entity894 ( @entity894 ), 19 by visual inspection and 13 by undefined methods. There was large intra-study variation in the plasma free haemoglobin level used to establish haemolysis ( @entity894 : mean  SD 846  795 mg/L, range 150-3000 mg/L; Visual: 850  436 mg/L, 500-3000 mg/L). Sixteen studies reported the analyte of interest, with only three studies reporting a haemoglobin level at which the specimen would be rejected. CONCLUSION: Despite haemolysis being a frequent and costly problem with a negative impact on @entity1 care, there is poor consistency in haemolysis detection and reporting between studies. Improved consistency would facilitate the generation of benchmark data used to create quality practices to monitor and reduce this leading cause of pre-analytical laboratory error.

Current Methods of Haemolysis Detection and Reporting as a Source of Risk to XXXX Safety: a Narrative Review.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity894 :: ('MESH:C566784', 'Disease') :: ['Haemolysis Index', 'HI'] @entity130 :: ('MESH:D014947', 'Disease') :: ['injury and infection'] @entity44 :: ('MESH:D013724', 'Disease') :: ['immaturity']
@entity1 :: (9606,Species) :: ['Patient']
