BACKGROUND: The craniofacial approach has greatly facilitated resections of @entity5 involving the base of the anterior cranial fossa when compared to either the transcranial or transfacial approach alone. MATERIAL AND METHODS: This approach was used in 11 @entity1 with @entity5 localized to the ethmoid sinus, orbit and bone or soft tissue of the base of the anterior part of the skull. By combining a low frontal or frontolateral craniotomy with resection of the facial skull, en bloc resections were accomplished. A frontogaleal periostal flap or a muscle flap from the temporal muscle was used to replace resected bone and to seal the skull base. RESULTS: There were no peri- or postoperative deaths. One @entity1 died due to local recurrence, one @entity1 is alive with @entity5 six years after surgery, and one is reoperated due to local recurrence. In addition one @entity1 developed recurrence of a previously treated @entity5 of the maxillary sinus. Two @entity1 developed @entity693 and one @entity5745 postoperatively. One @entity1 has partial @entity1018 and two @entity1 underwent @entity9467 . INTERPRETATION: The planning and execution of this type of surgery requires close interaction in an interdisciplinary team, in particular between neurosurgeon and head and neck surgeon.

[Resection of XXXX involving the anterior cranial fossa].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5745 :: ('MESH:D011007', 'Disease') :: ['pneumocephalus'] @entity1018 :: ('MESH:D054062', 'Disease') :: ['loss of vision'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant tumours', 'residual tumour', 'tumours', 'tumour'] @entity9467 :: ('MESH:D007766', 'Disease') :: ['dacryocystorhinostomy due to epiphora'] @entity693 :: ('MESH:D008581', 'Disease') :: ['meningitis']
@entity5 :: (MESH:D009369,Disease) :: ['malignant tumors']
