BACKGROUND: This study was done to determine if pre-radiotherapy (pre- @entity138 ) dental extractions reduce the risk of @entity7190 ( @entity7190 ). METHODS: Between 1987 and 2004, 413 @entity1 with @entity189 were treated with definitive @entity138 at the University of Florida. Dentate @entity1 underwent pretreatment dental evaluation. Teeth in the @entity138 field were usually extracted if thought to have poor long-term prognosis from @entity7291 . The endpoint was > or = grade 2 @entity7190 using a modified staging system. @entity1 were excluded for local recurrence, additional @entity138 above the clavicles, or head and neck surgery besides neck dissection. RESULTS: @entity7190 rates were as follows: edentulous, <1%; teeth in-field with pre- @entity138 extractions, 15%; and teeth in-field without pre- @entity138 extractions, 9%. @entity1 with poor in-field teeth and pre- @entity138 extractions had a higher 5-year incidence of @entity7190 than those who did not have pre- @entity138 extractions (16% vs 6%, p = .48). Likewise, for those with in-field teeth in good condition and pre- @entity138 extractions, the 5-year @entity7190 incidence was higher than for those who did not undergo extractions (15% vs 2%, p = .42). Multivariate analysis revealed increased @entity7190 risk with doses of >70 Gy, once-daily fractionation, or brachytherapy. CONCLUSION: Pre- @entity138 extractions do not appear to reduce the risk of @entity7190 .

Do pre-irradiation dental extractions reduce the risk of XXXX of the mandible?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity138 :: ('MESH:C563738', 'Disease') :: ['RT'] @entity7190 :: ('MESH:D010025', 'Disease') :: ['ORN', 'osteoradionecrosis'] @entity189 :: ('MESH:D002277', 'Disease') :: ['oropharyngeal carcinomas'] @entity7291 :: ('MESH:D009057', 'Disease') :: ['dental disease']
@entity7190 :: (MESH:D010025,Disease) :: ['osteoradionecrosis']
