BACKGROUND: @entity741 ( @entity741 ) resulting from primary percutaneous coronary intervention (PCI) for @entity583 ( @entity583 ) is considered harmful to the @entity1 , but its clinical significance remains unclear. This study explored the relationship of cardiac function examined by echocardiography and serum @entity908 kinase (CK) and CK-MB levels with @entity741 in a cohort of Chinese @entity583 @entity1 . MATERIAL/METHODS: We retrospectively analysed the clinical and angiographic data in 228 @entity583 @entity1 in whom the @entity1188 ( @entity1188 ) was successfully recanalized by primary PCI. Cardiac function was evaluated by use of echocardiography before discharge from hospital. RESULTS: The in-hospital mortality rate in the @entity741 group was 13.4% (16/119), which was significantly higher than the 4.6% (5/109) mortality rate in the non- @entity741 group (P=0.021). The median of peak serum CK level was remarkably lower in the suppression-type @entity741 group than in the non- @entity741 group. There were no significant differences in the peak serum CK or CK-MB levels between the irritation-type @entity741 group and the non- @entity741 group. The peak CK and CK-MB levels were significantly higher in the no-reflow-type @entity741 group than in the non- @entity741 group. Left ventricular ejection fraction in the no-reflow-type @entity741 group was significantly lower than in the non- @entity741 group; left ventricular end-diastolic volume was significantly higher than in the irritation-type @entity741 subgroup; and left ventricular end-systolic volume was greater than that in non- @entity741 group and suppression-type @entity741 group. CONCLUSIONS: @entity741 (especially the no-reflow type) may lead to @entity697 and increase the mortality rate. However, suppression- and irritation-type @entity741 may imply the existence of surviving myocardium.

Altered serum XXXX kinase level and cardiac function in ischemia-reperfusion injury during percutaneous coronary intervention.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute hemodynamic disorders'] @entity908 :: ('MESH:D003401', 'Chemical') :: ['creatine'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct-related artery', 'IRA'] @entity741 :: ('MESH:D017202', 'Disease') :: ['Myocardial ischemia-reperfusion injury', 'MIRI'] @entity583 :: ('MESH:D009203', 'Disease') :: ['AMI', 'acute myocardial infarction']
@entity908 :: (MESH:D003401,Chemical) :: ['creatine']
