BACKGROUND: Proximal @entity14 may arise from sessile serrated @entity1127 (SSPs), which are often inconspicuous during colonoscopy. The gross morphologic characteristics of SSPs have not been systematically described, and this omission may contribute to colonoscopists overlooking them. OBJECTIVES: To analyze the gross morphologic characteristics of SSPs detected during routine colonoscopy. DESIGN: Retrospective analysis of high-resolution endoscopic video clips depicting SSPs in situ. SETTING: Outpatient gastroenterology practice. @entity1 : A total of 124 subjects undergoing surveillance or screening colonoscopy after split-dose bowel preparation. INTERVENTIONS: Analysis of 158 SSPs performed by using validated descriptors. MAIN OUTCOME MEASUREMENTS: The prevalence of morphologic characteristics related to polyp shape, color, and texture. RESULTS: A total of 158 SSPs were studied. For 7 visual descriptors, a k coefficient of >=  0.7 was achieved, indicating good to excellent intraobserver agreement. The most prevalent visual descriptors were the presence of a mucous cap (63.9%), rim of debris or bubbles (51.9%), alteration of the contour of a fold (37.3%), and interruption of the underlying mucosal vascular pattern (32.3%). The most common "sentinel signs" were the presence of a mucous cap and alteration of the contour of a mucosal fold (each 24.6%), rim of debris or bubbles (21.7%), and a dome-shaped protuberance (20.3%). When comparing SSPs with @entity6523 , the frequencies of 5 of 7 morphologic characteristics and the distribution of sentinel signs differed (P < .01). LIMITATIONS: Single-site, retrospective analysis. CONCLUSIONS: SSPs exhibit distinct, variable morphologic characteristics. Many do not display classic features such as a mucous cap. Enhanced appreciation of these morphologic characteristics may improve SSP detection and thereby @entity14 prevention.

A morphologic analysis of sessile serrated XXXX observed during routine colonoscopy (with video).

@entity1 :: ('9606', 'Species') :: ['PATIENTS'] @entity6523 :: ('MESH:D018256', 'Disease') :: ['adenomatous polyps'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer']
@entity1127 :: (MESH:D011127,Disease) :: ['polyps']
