BACKGROUND: @entity424 ( @entity424 ) is a rare variant of ependymoma usually occurring in the conus medullaris or the filum terminale. It is usually a single encapsulated lesion. The aim of this study was to describe @entity1 with primary multifocal @entity424 of the filum terminale. METHODS: In this retrospective study, medical records of 22 @entity1 with spinal @entity424 who underwent surgical treatment in our hospital between January 2003 and January 2010 were enrolled. The study included 14 males and 8 females with age range from 11 to 66 years. There were 14 adult @entity1 and 8 pediatric @entity1 . The clinical presentation was @entity1643 ( @entity1643 ), @entity614 , focal @entity51 and @entity129 . RESULTS: Four cases presented with primary multifocal @entity424 at the filum terminale. All of them had chronic @entity1643 for at least 2-3 years. Three @entity1 had lower extremity @entity614 and one had urinary incontinence upon presentation. On magnetic resonance imaging (MRI), three @entity1 presented with two lesions and one @entity1 presented with three lesions at different spinal levels (a total of 9 MPEs). All lesions showed enhancement following @entity2287 administration on MRI. For 6 @entity5 en bloc resection was performed. Three lesions were removed gross totally in a piece-meal fashion. Following the surgical management, no @entity260 occurred. Three @entity1 underwent radiotherapy (RT. On an average follow-up of 6 years with clinical and MRI imaging, no recurrence was detected and symptoms of @entity1643 and neurologic findings improved after 2 months. CONCLUSIONS: Primary multifocal @entity424 is an extremely rare event occurring in the conus medullaris or filum terminale. The exact pathogenesis of this condition is unclear. Multifocal @entity424 may be due to multifocal growth of @entity5 , early stage of growth of a @entity5 or drop metastasis of @entity5 in the subarachnoid space. En bloc resection or piecemeal resection with radiotherapy were associated with satisfactory outcome without recurrence.

Primary multifocal XXXX of the filum terminale.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity129 :: ('MESH:D003389', 'Disease') :: ['cranial nerve palsy'] @entity1643 :: ('MESH:D017116', 'Disease') :: ['low back pain', 'LBP'] @entity424 :: ('MESH:D004806', 'Disease') :: ['Myxopapillary ependymoma', 'MPE'] @entity5 :: ('MESH:D009369', 'Disease') :: ['giant tumor', 'tumor', 'tumors'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complication'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficit'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium'] @entity614 :: ('MESH:D011843', 'Disease') :: ['radiculopathy']
@entity424 :: (MESH:D004806,Disease) :: ['myxopapillary ependymoma']
