PURPOSE: To compare the signal increase in cochlear lymph fluid on three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) in @entity1 with sudden @entity1274 ( @entity1274 ) between regular contrast 3D-FLAIR (FL) and @entity353 ( @entity353 ). METHODS: Twenty-five @entity1 with unilateral sudden @entity1274 and eight healthy volunteers were included. @entity1 were divided into two groups: the mild group consisted of 9 @entity1 , with an average hearing level of 60 dB or less; the severe group consisted of 16 @entity1 , with an average hearing level of more than 60 dB. All @entity1 and healthy volunteers underwent magnetic resonance (MR) cisternography for anatomical reference of the fluid space with FL and @entity353 at 3 T. The region of interest (ROI) was manually drawn on the mid-modiolar section of the MR cisternography around the cochlea. The ROI for noise was drawn within the air space. ROIs were copied onto the FL and @entity353 images. The contrast-to-noise ratio (CNR) between the affected and non-affected ear was measured in the @entity1 group and the CNR between the right and left ear was also measured in the control group. Differences in the CNR on FL and @entity353 images among the three groups were tested by one-way analysis of variance (ANOVA). RESULTS: There was a statistically significant difference in mean CNR on @entity353 among the three groups (P < 0.001). Furthermore, based on pairwise comparisons, there was a statistically significant difference between them in mean CNR on @entity353 (P < 0.05). There was no statistically significant difference in mean CNR on FL among the three groups (P = 0.074). CONCLUSIONS: @entity353 is more sensitive to signal alterations in cochleae with sudden @entity1274 than FL.

Heavily T2-Weighted 3D-FLAIR Improves the Detection of Cochlear Lymph Fluid Signal Abnormalities in XXXX with @entity1274 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity1274 :: ('MESH:D006319', 'Disease') :: ['sensorineural hearing loss', 'SNHL'] @entity353 :: ('MESH:D015431', 'Disease') :: ['HF', 'heavily T2-weighted 3D-FLAIR']
@entity1 :: (9606,Species) :: ['Patients']
