BACKGROUND: The performance of diffusion-weighted imaging parameters for characterizing @entity99 is controversial. PURPOSE: To compare the performances of apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM)-derived parameters, including the pure diffusion coefficient (D), perfusion coefficient (D*), and perfusion fraction (f), in the characterization of common solid @entity99 . MATERIAL AND METHODS: Twelve healthy volunteers and 43 @entity1 underwent free-breath diffusion-weighted magnetic resonance imaging (DW-MRI) of the liver using eight b values (10-800   s/mm(2)). Twelve regions of interest (ROIs) of normal liver tissue in healthy volunteers and 49 hepatic lesions (23 hepatocellular carcinomas [HCCs], 16 @entity2695 , and 10 metastases) were measured. Conventional ADC(0,500) and ADCtotal obtained by the mono-exponential model, as well as D, D*, and f were calculated. Student t-tests and receiver operating characteristic (ROC) analysis were also performed. RESULTS: ADC(0,500), ADCtotal, and D were significantly lower in the malignant group ([1.48        0.35]   *   10(-3)   mm(2)/s; [1.35        0.30]   *   10(-3)   mm(2)/s; [1.18        0.33]   *   10(-3)   mm(2)/s) compared to the @entity2695 group ([2.74        1.03]   * 10(-3)   mm(2)/s; [2.61        0.81]   *   10(-3)   mm(2)/s; [1.97        0.79]   *   10(-3)   mm(2)/s]. D* did not differ among multiple comparisons. For the area under the ROC curve (AUC-ROC), the maximum value was attained with ADCtotal (0.983) and was closely followed by ADC(0,500) (0.967), with lower values obtained for D (0.837), f (0.649), and D* (0.599). Statistically significant differences were found between the AUC-ROC of both ADCs (ADCtotal and ADC(0,500)) and D. There was no statistically significant difference between the AUC-ROC of ADCtotal and ADC(0,500). CONCLUSION: ADCs showed superior diagnostic performance compared to IVIM-derived parameters in detecting differences between the malignant group and @entity2695 group.

A comparative study of apparent diffusion coefficient and intravoxel incoherent motion-derived parameters for the characterization of common solid XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic tumors'] @entity2695 :: ('MESH:D006391', 'Disease') :: ['hemangioma', 'hemangiomas']
@entity99 :: (MESH:D056486,Disease) :: ['hepatic tumors']
