BACKGROUND: Five @entity1 undergoing intracytoplasmatic sperm injection (ICSI) considered to be at high risk of developing an @entity43 ( @entity43 ) from March to July 2002 underwent unilateral follicular aspiration. METHODS: When >/=15 follicles of 12-15 mm diameter in each ovary and a serum estrodial level >/=2500 pg/ml was present, follicular aspiration was performed unilaterally without @entity1465 administration. Ovarian stimulation was continued for 1-3 days in four @entity1 before @entity1 @entity1465 was given. In one @entity1 @entity1465 injection was administered at the evening after unilateral follicular aspiration. The oocyte retrieval from the contralateral ovary was performed 36 h after @entity1465 injection. By unilateral follicular aspiration two to six germinal vesicle (GV) oocytes could be retrieved. After in-vitro maturation of those oocytes ICSI was performed. RESULTS: In four @entity1 one to two oocytes were fertilized and cryopreserved. In one case only one triploid pronucleus (3PN) was observed. At the contralateral ovum-pick up after @entity1465 injection a median of 10 could be retrieved. After transfer of a median of 3 embryos, no pregnancy was achieved. Four of five @entity1 developed a severe @entity43 and were hospitalized for a median of 3 days. CONCLUSION: Unilateral follicular aspiration and continuation of stimulation therefore can not be recommended for the prevention of @entity43 .

Unilateral follicular aspiration and in-vitro maturation before contralateral oocyte retrieval: a method to prevent XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'human', 'woman', 'patients'] @entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian hyperstimulation syndrome', 'OHSS'] @entity1465 :: ('93659', 'Gene') :: ['hCG', 'chorionic gonadotrophin (hCG)']
@entity43 :: (MESH:D010051,Disease) :: ['ovarian hyperstimulation syndrome']
