Object While several approaches have been described for optic nerve decompression, the endoscopic endonasal route is gaining favor because it provides excellent exposure of the optic canal and the orbital apex in a minimally invasive manner. Very few studies have detailed the experience with nontraumatic optic nerve decompressions, whereas traumatic cases have been widely documented. Herein, the authors describe their preliminary experience with endoscopic endonasal decompression for nontraumatic @entity1781 (NONs) to determine the procedure's efficacy and delineate its potential indications and limits. Methods The medical reports of @entity1 who had undergone endoscopic endonasal optic nerve and orbital apex decompression for NONs at the Lyon University Neurosurgical Hospital in the period from January 2012 to March 2014 were reviewed. For all cases, clinical and imaging data on the underlying pathology and the @entity1 , including demographics, preoperative and 6-month postoperative ophthalmological assessment results, symptom duration, operative details with video debriefing, as well as the immediate and delayed postoperative course, were collected from the medical records. Results Eleven @entity1 underwent endoscopic endonasal decompression for NON in the multidisciplinary skull base surgery unit of the Lyon University Neurosurgical Hospital during the 27-month study period. The mean @entity1 age was 53.4 years, and there was a clear female predominance (8 females and 3 males). Among the underlying pathologies were 4 @entity1653 (36%), 3 @entity1781 (27%), and 1 each of trigeminal @entity2950 (9%), orbital apex @entity1653 (9%), ossifying @entity81 (9%), and @entity6437 of the orbit (9%). Fifty-four percent of the @entity1 had improved visual acuity at the 6-month follow-up. Only 1 @entity1 whose @entity1653 had been treated at the @entity1952 stage continued to worsen despite surgical decompression. The 2 @entity1 presenting with preoperative @entity1829 totally recovered. One case of @entity86 was successfully treated using balloon inflation, and 1 case of air swelling of the orbit spontaneously resolved. Conclusions Endoscopic endonasal optic nerve decompression is a safe, effective, and minimally invasive technique affording the restoration of visual function in @entity1 with nontraumatic compressive processes of the orbital apex and optic nerve. The timing of decompression remains crucial, and @entity1 should undergo such a procedure early in the disease course before @entity1952 .

Endoscopic endonasal optic nerve and orbital apex decompression for nontraumatic XXXX : surgical nuances and review of the literature.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1952 :: ('MESH:D009896', 'Disease') :: ['optic atrophy', 'optic nerve atrophy'] @entity6437 :: ('MESH:D006104', 'Disease') :: ['inflammatory pseudotumor'] @entity1653 :: ('MESH:D008579', 'Disease') :: ['sphenoorbital meningiomas', 'sphenoorbital meningioma', 'meningioma'] @entity1781 :: ('MESH:D009901', 'Disease') :: ['optic nerve meningiomas', 'optic neuropathies'] @entity1829 :: ('MESH:D010211', 'Disease') :: ['papilledema'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative epistaxis'] @entity2950 :: ('MESH:D009463', 'Disease') :: ['neuroma'] @entity81 :: ('MESH:D005350', 'Disease') :: ['fibroma']
@entity1781 :: (MESH:D009901,Disease) :: ['optic neuropathy']
