OBJECTIVES: To assess whether volumetric cerebrospinal fluid ( @entity2841 ) MRI can be used as a surrogate for @entity1010 assessment and to evaluate how the T2 of the @entity2841 relates to @entity1010 . METHODS: Twenty-eight subjects [mean age 64 (sd 2) years] were included; T1-weighted and @entity2841 MRI were performed. The first echo data of the @entity2841 MRI sequence was used to obtain intracranial volume, @entity2841 partial volume was measured voxel-wise to obtain @entity2841 volume (VCSF) and the @entity61539 ( @entity61539 ) was calculated. The correlation between VCSF / @entity61539 and @entity1010 scores [ @entity194 ( @entity194 ) and medial temporal lobe @entity194 (MTA)] was evaluated. RESULTS: Relative total, peripheral subarachnoidal, and ventricular VCSF increased significantly with increased scores on the @entity194 and MTA (R   =   0.83, 0.78 and 0.78 and R   =   0.72, 0.62 and 0.86). Total, peripheral subarachnoidal, and ventricular T2 of the @entity2841 increased significantly with higher scores on the @entity194 and MTA (R   =   0.72, 0.70 and 0.49 and R   =   0.60, 0.57 and 0.41). CONCLUSION: A fast, fully automated @entity2841 MRI volumetric sequence is an alternative for qualitative @entity194 scales. The T2 of the @entity2841 is related to @entity1010 and could thus be a marker of @entity179 . KEY POINTS:     A 1:11  min @entity2841 MRI volumetric sequence can evaluate @entity1010 .     @entity2841 MRI provides accurate @entity194 assessment without partial volume effects.     @entity2841 MRI data can be processed quickly without user interaction.     The measured @entity6402 of the @entity2841 is related to @entity1010 .

Cerebrospinal fluid volumetric MRI mapping as a simple measurement for evaluating XXXX .

@entity61539 :: ('292;1437', 'Gene') :: ['T2,CSF', 'T2 of CSF'] @entity1010 :: ('MESH:C566985', 'Disease') :: ['brain atrophy'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative disease'] @entity194 :: ('MESH:D001284', 'Disease') :: ['global cortical atrophy', 'GCA', 'atrophy'] @entity6402 :: ('292', 'Gene') :: ['T 2'] @entity2841 :: ('1437', 'Gene') :: ['CSF']
@entity1010 :: (MESH:C566985,Disease) :: ['brain atrophy']
