OBJECTIVE: To compare @entity1 -reported @entity158 , provider- reported ease of use, and tissue sampling adequacy between endometrial biopsy instruments. METHODS: @entity1 presenting for endometrial biopsy were randomized to either Pipelle or Explora curette. The primary outcome was @entity1 -reported @entity158 with biopsy as measured by a 100-mm visual analog scale. Secondary outcomes included the adequacy of biopsy sample and provider-reported ease of instrument use. RESULTS: Groups were similar in respect to age, parity, ethnicity, level of @entity1834 , menopausal status, and biopsy indication. The most common indication for biopsy was abnormal uterine @entity548 . Subject reported @entity158 with biopsy was similar between groups (Pipelle, 6.21    2.41 cm; Explora, 6.91    2.88 cm; P=.14), as was provider-reported ease of use. Although procedure length was significantly shorter for @entity1 in the Pipelle group (4.05    1.48 minutes compared with 5.27    2.53 minutes; P=.007), 38% of Pipelle procedures required two or more passes to obtain a sample compared with only 9% using the Explora (P=.004). The Explora group had a higher proportion of adequate samples (97% compared with 91%; P=.33). CONCLUSION: @entity1 's @entity158 during endometrial biopsy does not differ by type of biopsy instrument used. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov NCT00613925.

XXXX experienced using two different methods of endometrial biopsy: a randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'Women', 'patient'] @entity1834 :: ('MESH:D004412', 'Disease') :: ['dysmenorrhea'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding']
@entity158 :: (MESH:D010146,Disease) :: ['Pain']
