@entity3 ( @entity3 ) originating from the paranasal sinuses can cause an intracranial growth mainly along the skull base and larger vessels. This study reports our experience in the diagnosis and treatment of a series of @entity1 with @entity3 . A retrospective chart review of four @entity1 with chronic invasive @entity932 was performed. Clinical signs, physical examinations, radiographs, histological samples, and outcome were demonstrated. The @entity1 demonstrated different symptoms like exophthalmus, @entity4610 , @entity1018 , and hypaesthesia of the ophthalmic and maxillary nerve. Computed tomography and MRI revealed extensive sino-orbital and skull base lesions. The @entity1 were treated with @entity146 endonasal debridement, intravenous antifungal agents and daily irrigations with antimycotic suspensions. Furthermore, we applied hyperbaric oxygenation. Two @entity1 died from complications due to @entity510 and accompanied complications respectively. Despite the high mortality rate @entity1 with an @entity3 can be effectively treated in some cases by an early and rigorous treatment schedule using all surgical and conservative therapeutic options.

XXXX of the paranasal sinuses and the skull base.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1018 :: ('MESH:D054062', 'Disease') :: ['loss of vision'] @entity932 :: ('MESH:D020300', 'Disease') :: ['intracranial aspergillosis'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity510 :: ('MESH:D013345', 'Disease') :: ['subarachnoidal hemorrhage'] @entity4610 :: ('MESH:D009886', 'Disease') :: ['ophthalmoplegia'] @entity3 :: ('MESH:D009362', 'Disease') :: ['invasive aspergillosis', 'Invasive aspergillosis', 'IA']
@entity3 :: (MESH:D009362,Disease) :: ['Invasive aspergillosis']
