INTRODUCTION AND OBJECTIVES: @entity4854 at admission seems to identify a subgroup of @entity1 with @entity1187 with poorer outcome. The aim of this study was to evaluate the impact of the glycemic variation during hospitalization in long-term mortality in nondiabetic @entity1 . METHODS: Retrospective study of 2043 consecutive @entity1 without known @entity6 admitted for @entity1187 in a single coronary care unit from May 2007 through August 2013. The population was divided in quartiles regarding glycemia at admission ( <= 90 mg/dL, n  =  374; 90-140 mg/dL, n  =  1307; 141-180 mg/dL, n  =  230; >=  181mg/dL, n  =  111) and the mortality rate quantified for @entity1 with glycemic variation above/below the mean for their respective quartile. The median follow-up was about 1200 days. RESULTS: The all-cause mortality during follow-up was significantly and successively higher in the upper quartiles (9.1%, 9.7%, 13.5% and 18.9%; P  =  .007). Multivariate regression analysis showed that @entity4854 at admission (>=   181mg/dL) was a strong independent predictor of mortality during follow-up (hazard ratio = 1.74; 95% confidence interval, 1.07-2.8; P  =  .027). In the fourth quartile (>=   181mg/dL), the mortality is higher in @entity1 with higher variations of glycemia (37.5% vs 8.5%; P  <  .001). CONCLUSIONS: @entity4854 at admission is a predictor of all-cause mortality in our population. The mortality is higher in @entity1 with higher glycemic variations. More studies are needed to confirm these data.

Blood glucose in XXXX . How low should you go?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndrome', 'acute coronary syndromes'] @entity4854 :: ('MESH:D006943', 'Disease') :: ['hyperglycemia', 'Hyperglycemia'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus']
@entity1187 :: (MESH:D054058,Disease) :: ['acute coronary syndromes']
