BACKGROUND: A double stent system (covered stent in uncovered stent) was designed to provide long-term patency without @entity5 ingrowth or stent-related complications, such as stent migration, @entity2679 , or @entity788 . PURPOSE: To investigate the safety and efficacy of double stents in @entity1 with @entity2876 . MATERIAL AND METHODS: This prospective, nonrandomized, multicenter study enrolled 160 consecutive @entity1 (102 @entity1 ; mean age, 64 years; range, 33-91 years) with @entity2876 treated with a double stent system from January 2010 to March 2012. RESULTS: The technical success rate of the double stent placement was 100%. No stent migration was observed. Procedure-related minor (self-limiting @entity7252 [n   =   6] and @entity255 [n   =   2]) and major ( @entity788 [n   =   16], @entity2679 [n   =   3], and @entity99 [n   =   2]) complications occurred in a total of 29 @entity1 . The mean serum @entity648 level, which was 8.9        5.6   mg/dL before drainage, decreased to 2.2        4.6   mg/ @entity19444 month after stent placement (P   <   0.001). Successful internal drainage was achieved in 148 @entity1 (92.5%). During the mean follow-up period of 205 days, acute @entity2679 (n   =   3) and @entity99 (n   =   2) occurred in five @entity1 . The median @entity1 survival and stent patency time were 135 days (95% confidence interval [CI], 96-160 days) and 114 days (95% CI, 83-131 days), respectively. Of 153 @entity1 , 22 (14.4%) presented with stent dysfunction due to sludge incrustation (n   =   17), @entity5 overgrowth (n   =   4), or blood clot (n   =   1), and required repeat intervention. @entity5 ingrowth was not observed in any of these @entity1 . CONCLUSION: Percutaneous treatment of malignant @entity2876 using a double stent safely and effectively achieves internal biliary drainage.

A prospective, multicenter study of a double stent system for palliative treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'men'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatitis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumor'] @entity648 :: ('MESH:D001663', 'Chemical') :: ['bilirubin'] @entity19444 :: ('249390', 'Gene') :: ['dL 1'] @entity2679 :: ('MESH:D002764', 'Disease') :: ['cholecystitis'] @entity2876 :: ('MESH:D001656', 'Disease') :: ['extrahepatic biliary obstruction', 'malignant extrahepatic biliary obstructions'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic abscess'] @entity255 :: ('MESH:D002761', 'Disease') :: ['cholangitis'] @entity7252 :: ('MESH:D006431', 'Disease') :: ['hemobilia']
@entity2876 :: (MESH:D001656,Disease) :: ['malignant extrahepatic biliary obstructions']
