OBJECTIVE: To explore the long-term efficacy and safety of @entity432 ( @entity432 ) in the treatment of intractable @entity9303 ( @entity9303 ) so as to provide an alternative surgical procedure for treating this disorder. METHODS: Data from Forty-nine @entity1 , who were referred to our hospital and diagnosed with unilateral @entity9303 strictly meeting the criteria issued by Chinese Academy of Otolaryngology-Head and Neck Surgery Committee (2006) from Dec. 2010 to Jul. 2012, were retrospectively analyzed in this work. Forty-nine @entity1 , in whom the standardized conservative treatment was given at least one year and frequent vertigo still occurred, received @entity432 . Vertigo control and auditory function were measured. Pure tone audiometry, caloric test, and cervical vestibular evoked myogenic potential (cVEMP) were performed for evaluation of audiological and vestibular function. Magnetic resonance hydrograph of inner ear was performed in @entity1 received @entity432 after 2 years for the observation of morphology of membranous labyrinth. Postoperative follow-up period was more than 2 years. RESULTS: According to the preoperative staging of hearing, among these 49 @entity1 , there were 2 cases in stage II (with an average hearing threshold of 25-40 dBHL), 40 in stage III (41-70 dBHL) and 7 in stage IV (over 70 dBHL). Vertigo was controlled effectively in all 49 cases in two-year follow-up, of which 40 cases (81.6%) were completely controlled and 9 cases (18.4%) were substantially controlled after surgery. The rate of hearing preservation was 69.4% and the rate of @entity393 was 30.6%. Post-operatively, all @entity1 suffered from temporary vertigo and @entity74 . Vertigo was disappeared in all @entity1 within 3-5 days, while averagely recovered after 13.5 days. Two years afer treatment, loss of semicircular canal function by caloric test was found in the operation side of all @entity1 and no change in cVEMP test was noted. All @entity1 had no @entity3541 , @entity5173 , and other complications. Magnetic resonance hydrograph of inner ear showed that endolymph fluid in the position of plugging had no water after 2-years of @entity432 . CONCLUSIONS: @entity432 , which can reduce vertiginous symptoms effectively in @entity1 with intractable @entity9303 in long-term follow-up, represents an effective and safe therapy for this disorder. @entity432 is expected to be used as an alternative procedure for the treatment of @entity9303 in selected @entity1 suffering from severe @entity393 or recurrence after endolymphatic sac surgery.

[Long-term efficacy of XXXX in the treatment of intractable @entity9303 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity9303 :: ('MESH:D008575', 'Disease') :: ["Meniere's disease", 'MD'] @entity5173 :: ('MESH:D065634', 'Disease') :: ['cerebrospinal fluid leakage'] @entity74 :: ('MESH:D030342', 'Disease') :: ['balance disorders'] @entity3541 :: ('MESH:D005158', 'Disease') :: ['facial paralysis'] @entity432 :: ('MESH:D001157', 'Disease') :: ['triple semicircular canal occlusion', 'TSCO'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss']
@entity432 :: (MESH:D001157,Disease) :: ['triple semicircular canal occlusion']
