OBJECTIVE: To assess the frequency and independent predictors of severe @entity810 in @entity1 resuscitated from out-of-hospital @entity2224 @entity1167 . DESIGN: A cohort study with a minimum follow-up of 6 months. SETTING: Emergency department of a tertiary care 2200-bed university hospital. @entity1 AND @entity1 : Consecutive adult (> 18 years) @entity1 admitted from 1 July 1991 to 31 October 1997 after witnessed @entity2224 out-of-hospital @entity1167 and successful resuscitation. MEASUREMENTS AND RESULTS: @entity810 was defined as a 25% decrease of @entity1011 clearance within 24 h after admission. Out of 187 eligible @entity1 (median age 57 years, 146 male), @entity810 occurred in 22 @entity1 (12%); in 4 @entity1 (18%) renal replacement therapy was performed. @entity712 (OR 6.0, 95% CI 1.6-21.7; p = 0.007), history of @entity101 (OR 4.4, 95% CI 1.3-14.7; p = 0.02) and total dose of @entity1425 administered ( @entity24773 , 95% CI 1.0-1.2; p = 0.009) were independent predictors of @entity810 . Duration of @entity1167 , pre-existing @entity8 at admission were not independently associated with renal outcome. CONCLUSIONS: Severe progressive @entity810 after cardiopulmonary resuscitation (CPR) is rare. Pre-existing haemodynamics seem to be more important for the occurrence of @entity810 than actual hypoperfusion during resuscitation.

XXXX after successful cardiopulmonary resuscitation.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS', 'PARTICIPANTS'] @entity8 :: ('MESH:D007674', 'Disease') :: ['impaired renal function and blood pressure'] @entity712 :: ('MESH:D006333', 'Disease') :: ['Congestive heart failure'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1425 :: ('MESH:D004837', 'Chemical') :: ['epinephrine'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['ventricular fibrillation'] @entity810 :: ('MESH:D058186', 'Disease') :: ['Acute renal failure', 'acute renal failure'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['cardiac arrest'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity24773 :: ('81399', 'Gene') :: ['OR 1.1']
@entity810 :: (MESH:D058186,Disease) :: ['Acute renal failure']
