PURPOSE: To report the clinical and immunopathologic features and the response to therapy in a series of six @entity1 with @entity2318 due to lichen planus. DESIGN: Retrospective case series. METHODS: All six @entity1 were seen in an ocular pemphigoid clinic. Clinical, immunopathologic, and serologic features were evaluated and therapeutic response in each @entity1 was monitored. RESULTS: All six @entity1 had evidence of conjunctival scarring. Five @entity1 had @entity8619 ; one @entity1 had involvement of the skin. Histologic findings consisted of thickened epithelium and an interface lymphocytic infiltrate along the lamina propria. In three @entity1 , electron microscopy of the conjunctiva revealed thickening, fragmentation, and duplication of the basement membrane zone. Direct immunofluorescence examination of the conjunctiva and oral mucosa demonstrated linear and shaggy fibrinogen deposition along the basement membrane zone, confirming the diagnosis of lichen planus. All six @entity1 were placed on immunosuppressive therapy with control of the disease. However, only one @entity1 was able to discontinue the anti-inflammatory medication and have the @entity9338 in remission. CONCLUSIONS: @entity9338 should be included in the differential diagnosis of @entity2318 . Performing appropriate investigations to distinguish conjunctival lichen planus from other @entity792 such as mucous membrane pemphigoid is critical to managing the @entity1 with @entity2318 appropriately. Oral @entity205 effectively controlled the conjunctival lichen planus in four of the six cases.

XXXX and @entity2318 : characterization of five cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2318 :: ('MESH:D002921', 'Disease') :: ['cicatrizing conjunctivitis'] @entity205 :: ('MESH:D016572', 'Chemical') :: ['cyclosporine'] @entity9338 :: ('MESH:D008010', 'Disease') :: ['lichen planus remain', 'Lichen planus'] @entity8619 :: ('MESH:D017676', 'Disease') :: ['lichen planus of the oral mucosa and gingiva'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmune diseases']
@entity9338 :: (MESH:D008010,Disease) :: ['Lichen planus']
