UNASSIGNED: Although @entity1442 have been made, a significant gap exists between the vast knowledge accumulated concerning @entity370 in recent years and our understanding of this disease. OBJECTIVE: Describe the main clinical and histopathological findings associated with @entity370 and to investigate the relationship of these @entity272 with systemic involvement. A retrospective review of 41 @entity1 who were diagnosed with @entity370 was done. The study included 34 females and 7 males. @entity262 occurred frequently in @entity1 with @entity1252 and @entity75 . Systemic symptoms were observed more commonly in @entity1 with raised serum @entity1289 levels (84.6% vs. 40%; p<0.05). Our study also indicated that @entity1 with @entity272 that were associated with systemic symptoms had a more chronic form of the disease than @entity1 with only cutaneous lesions (91.6% vs. 29.4%; p<0.001). Additionally, complete resolution of cutaneous lesions was observed more frequently in @entity1 with no associated systemic symptoms (66.6% vs. 23.5%; p<0.05). Interestingly, we found that @entity1 with a moderate/severe granulomatous infiltrate in their biopsies had a more severe clinical presentation during the course of the disease, with a more generalized skin involvement (65.6% vs. 30%) as well as a more chronic course of the disease (56.3% vs. 30%). Another interesting histopathological finding observed was the presence of a grenz zone in 20 cases (47.6%). A correct and methodical clinicopathological correlation is important for our clinical practice because it can give us useful clues to the diagnosis and prognosis of this disease.

Prognostic value of XXXX in @entity370 : Clinical and histopathological clues.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1289 :: ('1636', 'Gene') :: ['ACE'] @entity75 :: ('MESH:D001927', 'Disease') :: ['nodulo-plaque type lesions'] @entity262 :: ('MESH:D034721', 'Disease') :: ['Systemic disease'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['lupus pernio'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['tremendous advances'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesions'] @entity370 :: ('MESH:D012507', 'Disease') :: ['cutaneous sarcoidosis', 'sarcoidosis']
@entity272 :: (MESH:D012871,Disease) :: ['skin lesions']
