BACKGROUND: This study sought to evaluate the relation between long-term segmental and global functional outcome after revascularisation in @entity1 with chronic @entity1002 (LVD) and baseline markers of viability: late @entity2287 enhancement (LGE) transmurality and contractile reserve (CR). METHODS: Forty-two @entity1 with chronic @entity1002 underwent low-dose @entity452 - ( @entity258 ) and late @entity2287 enhancement (LGE) cardiovascular magnetic resonance (CMR) before surgical or percutaneous revascularisation. Regional and global @entity1002 ( @entity1002 ) functions and LGE were repeatedly assessed 6        1 and 35        6  months after revascularisation. In total, 319 at baseline dysfunctional and successfully revascularised segments were available for statistical analysis. RESULTS: The likelihood of long-term functional improvement was directly related to the presence of CR and inversely related to both the LGE and the degree of contractile dysfunction at baseline. The time course of functional improvement was protracted, with significantly more delay in segments with more extensive LGE (p   =   0.005) and more severe contractile dysfunction at baseline (p   =   0.002). The presence of CR was the predictor of earlier functional improvement (p   <   0.0001). Using a definition of viable segment as a segment without any LGE or with any LGE and producing CR during @entity258 stimulation, >= 55% of viable segments from all dysfunctional and revascularised segments in a @entity1 was the only independent predictor of significant improvement (>= 5%) in the @entity1002 ( @entity1002 ) after revascularisation, with a 72% sensitivity and an 80% specificity (AUC 0.76, p   =   0.014). Reverse @entity1002 remodelling was observed in @entity1 who had a significant amount of viable @entity1562 successfully revascularised. CONCLUSIONS: In @entity1 with chronic @entity1002 , improvement of dysfunctional but viable @entity1562 can be considerably delayed. Both the likelihood and the time course of functional improvement are related to the LGE, CR and the degree of contractile dysfunction at baseline. At 35        6  months after revascularisation, @entity1 with >= 55% of viable segments from all dysfunctional and revascularised segments significantly improve @entity1002 and experience reverse @entity1002 remodelling. A combination of @entity258 -CMR and LGE-CMR is a simple and powerful tool for identifying which @entity1 with impaired @entity1002 function will benefit from revascularisation.

Prediction of long-term segmental and global functional recovery of hibernating XXXX after revascularisation based on low dose @entity452 and late @entity2287 enhancement cardiovascular magnetic resonance.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['dobutamine'] @entity258 :: ('MESH:D009800', 'Disease') :: ['LDD'] @entity1562 :: ('MESH:D017682', 'Disease') :: ['myocardium'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium'] @entity1002 :: ('MESH:D018487', 'Disease') :: ['ischaemic LVD', 'LV', 'left ventricular ejection fraction', 'left ventricular', 'LVEF', 'ischaemic left ventricular dysfunction']
@entity1562 :: (MESH:D017682,Disease) :: ['myocardium']
