OBJECTIVE: To summarize the experience with diagnosis and therapy of @entity1412 ( @entity1412 ). METHODS: Thirteen @entity1 with @entity1412 who had undergone total colectomy were analyzed retrospectively. RESULTS: In 5 @entity1 with benign and 8 @entity1 with @entity1412 , their average age at operation was 31.5 years (range 10 - 57), 25 years in benign @entity1 and 36 years in malignant @entity1 . @entity74 histories were found in 8 @entity1 in 6 families. Nineteen @entity1 were determined in 6 families in 3 generations. Seven familial members died of @entity14 in 4 families. History lasted 2 - 20 years. The number of @entity1412 was more than 100. All @entity1 underwent total colectomy, ileostomy or anus-preserving surgery with or without @entity4628 . All @entity1 without @entity5 survived. The longest one exceeded 25 years, but 3/8 @entity1 with @entity5 developed @entity3 of liver, brain and abdomen within 6 months after surgery. CONCLUSIONS: @entity1412 will turn to be @entity5 if not removed. Total colectomy or proctocolectomy should be performed before @entity5 . Total colectomy, preserving muscular sheath of the rectum after mucosectomy, @entity4628 -anal @entity254 may be the operative choice for @entity1412 .

[Diagnosis and treatment of XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4628 :: ('MESH:D007077', 'Disease') :: ['ileal pouch'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'canceration'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity74 :: ('MESH:D030342', 'Disease') :: ['Familial inherited'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity1412 :: ('MESH:D011125', 'Disease') :: ['familial adenomatous polyposis', 'malignant adenomatous polyposis', 'FAP', 'adenomatous polyposis']
@entity1412 :: (MESH:D011125,Disease) :: ['familial adenomatous polyposis']
