Thirty @entity1 with @entity1723 ( @entity1723 ) were electrophysiologically evaluated. In addition to the conventional motor and sensory nerve conduction studies, intrafascicular microneurography was performed in the median nerve. In this method a @entity5335 microelectrode was inserted into the median nerve trunk at the elbow, and a compound nerve action potential (CNAP) was recorded with supramaximal electrical stimulation at the wrist. The subjects' age ranged from 8 to 31 years with an average (SD) of 15.4 (6.2) years; the disease duration varied from 1 to 23 years with an average (SD) of 8.3 (5.8) years. @entity305 index (PNI), expressed as a mean percentage of the normal for twelve indices over the four nerves obtained by motor conduction studies, was 93.9% on the average in @entity1 with @entity1723 . The mean amplitude of CNAP obtained by intrafascicular microneurography was 417 microV. These results indicate that @entity16 in @entity1723 is milder than that in adult @entity2175 ( @entity2175 ). The mean value of PNI decreased at a rate of 0.56% per year; the mean glycosylated hemoglobin (A1c) level was as high as 8.2 +/- 0.9%, findings consistent with those of the previous analysis of adult @entity1 with @entity2175 . The PNI value had a significant negative correlation with the duration of @entity6 (p < 0.001) and with mean glycosylated hemoglobin (A1c) level (p < 0.01). CNAP amplitude had a tendency to correlate with duration of @entity6 (p < 0.1). In @entity1 with @entity1723 we can tell exactly when the disease occurred. @entity16 in juvenile @entity1723 was identical to that of adult @entity2175 . Careful management of @entity6 is of importance to prevent the progression of @entity16 .

[Electrophysiological evaluation of XXXX in juvenile insulin dependent diabetics].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5335 :: ('MESH:D014414', 'Chemical') :: ['tungsten'] @entity2175 :: ('MESH:D003924', 'Disease') :: ['non-insulin dependent diabetes mellitus', 'NIDDM'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity16 :: ('MESH:D009422', 'Disease') :: ['Progression of neuropathy', 'neuropathy'] @entity305 :: ('MESH:D011115', 'Disease') :: ['Polyneuropathy'] @entity1723 :: ('MESH:D003922', 'Disease') :: ['IDDM', 'juvenile insulin dependent diabetes mellitus']
@entity305 :: (MESH:D011115,Disease) :: ['polyneuropathy']
