Multiple acute @entity2806 in different hemispheres or vascular territories are mainly considered to be of proximal embolic origin. However, despite careful diagnostic work-up, the etiological classification often stays undetermined. We propose that multiple acute @entity2806 can sometimes be a phenomenon observed in @entity6249 ( @entity6249 ). From a prospectively collected database of more than 7,000 @entity64 @entity1 , 173 @entity1 with acute bihemispheric @entity1188 were identified. We analyzed those subjects with multiple small (< 15 mm   ) subcortical acute @entity2806 on diffusion-weighted MRI (DWI) and concomitant severe @entity6249 (Fazekas grades II-III) without a proximal embolic source as evaluated by cardiological investigations. Twenty @entity1 (mean age 66    12 years, 12 @entity1 ) with a mean number of 2.95    1.24 acute lesions on DWI (range of 2-7 lesions per @entity1 ) were identified (n = 5 Fazekas II  , n = 15 Fazekas III  ). Most of the lesions were located in typical areas of @entity1188 . The mean NIHSS score on admission was 2.95    2.0 (range 0-8). Multiple acute @entity2806 in different vascular territories might not always be of proximal cardiovascular embolic origin. Simultaneous small subcortical @entity2806 may reflect remote @entity63 due to @entity6249 reflecting simultaneous @entity409 .

Multiple subcortical acute XXXX reflect @entity6249 rather than cardiogenic embolism.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['ischemic lesions'] @entity6249 :: ('MESH:D059345', 'Disease') :: ['SVD', 'small vessel disease'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia'] @entity409 :: ('MESH:D008107', 'Disease') :: ['hemorheological dysfunction'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['lacunar infarction', 'infarction']
@entity2806 :: (MESH:D002545,Disease) :: ['ischemic lesions']
