BACKGROUND: Long-term @entity26 therapy (LTOT) improves the survival time in hypoxemic @entity1030 . Despite warnings about potential dangers, a considerable number of @entity1 continue to smoke while on LTOT. The incidence of @entity130 related to LTOT is unknown. The aim of this study was to estimate the rate of @entity130 requiring health care contact during LTOT. METHODS: Prospective, population-based, consecutive cohort study of @entity1 starting LTOT from any cause between January 1, 1992 and December 31, 2009 in the Swedish National Register of @entity1576 (Swedevox). RESULTS: In total, 12,497 @entity1 (53% @entity1 ) were included. The mean (standard deviation) age was 72  9 years. The main reasons for starting LTOT were @entity1030 (75%) and @entity3794 (15%). Only 269 (2%) were active smokers when LTOT was initiated. The median follow-up time to event was 1.5 years (interquartile range, 0.55-3.1). In total, 17 @entity1 had a diagnosed @entity130 during 27,890 @entity1 -years of LTOT. The rate of @entity130 was 61 (95% confidence interval, 36-98) per 100,000 @entity1 -years. There was no statistically significant difference in the rate of @entity130 between ever-smokers and never-smokers, or between @entity1 and @entity1 . CONCLUSION: The rate of @entity130 in @entity1 on LTOT seems to be low in Sweden. The strict requirements in Sweden for smoking cessation before LTOT initiation may contribute to this finding.

The risk of @entity130 during long-term XXXX therapy: a 17-year longitudinal national study in Sweden.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'person', 'people', 'men'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity3794 :: ('MESH:D011658', 'Disease') :: ['pulmonary fibrosis'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['Respiratory Failure'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease'] @entity130 :: ('MESH:D014947', 'Disease') :: ['burn injuries', 'burn injury']
@entity26 :: (MESH:D010100,Chemical) :: ['oxygen']
