The growth hormone secretagogue-receptor (GHS-R) is an endogenous receptor for the gut hormone ghrelin. Here we report the identification and characterization of @entity21502 in @entity26584 , @entity26584 . The full-length @entity21502 cDNA contained a 1803-bp coding domain sequence which encoded a peptide of 360 @entity535 residues. Comparison analysis revealed that the @entity535 sequences of @entity21502 were highly conserved in vertebrates and shared 97% @entity535 identity with @entity3392 ( @entity3392 ), 96% with jian @entity7136 ( @entity7136 . Jian) and 93% with @entity2083 ( @entity2083 ). The @entity21502 showed the highest level of mRNA expression in the pituitary, followed by the brain and liver, and the lowest expression was observed in the hindgut. Intraperitoneally injected with @entity26584 ghrelin (50, 100 and 150ng/g body weight (BW)), @entity26584 showed greater mRNA expression of @entity21502 in the pituitary compared with saline injected at 0.5h postinjection. It was observed that food deprivation could promote the expression of ghrelin and @entity21502 in the pituitary, demonstrating that nutritional status can influence the expression of both ghrelin and @entity21502 in the pituitary. After a 2- or 4-week fast, plasma growth hormone (GH) increased, was positively correlated with ghrelin and @entity21502 mRNA expression levels in the pituitary. These results suggested that the involvement of ghrelin/ @entity21502 systems in mediating the effects of nutritional status and ghrelin on growth processes in @entity26584 .

Sequence, genomic organization and expression of ghrelin receptor in @entity26584 , XXXX .

@entity535 :: ('CHEBI:33704', 'Chemical') :: ['amino acid'] @entity2083 :: ('7957', 'Species') :: ['goldfish', 'Carassius auratus'] @entity26584 :: ('7959', 'Species') :: ['grass carp', 'Ctenopharyngodon idellus'] @entity7136 :: ('7962', 'Species') :: ['carp', 'Cyprinus carpio var'] @entity3392 :: ('7955', 'Species') :: ['Danio rerio', 'zebrafish'] @entity21502 :: ('795753(Tax:7955)', 'Gene') :: ['GHS-R1a']
@entity26584 :: (7959,Species) :: ['Ctenopharyngodon idellus']
