PURPOSE: The impact of intraoperative @entity7048 on postoperative @entity410 after elective repair of an @entity438 was evaluated. METHODS: Chart review of a prospectively accrued database was performed for @entity1 admitted from January 1, 2003, through December 31, 2013. @entity1 were included in the study if they underwent elective repair of an unruptured @entity439 with surgical clipping or wrapping. The primary objective was to determine if the use of @entity7048 increased @entity1 ' odds of having a @entity410 within six hours of surgical intervention. Univariate comparisons were conducted on all variables for @entity1 who received @entity7048 and @entity1 who were treated with other antibiotics. Multivariable logistic regression was performed to assess the impact of @entity7048 administered intraoperatively on postoperative @entity410 , while accounting for other covariates. RESULTS: Of the 520 @entity1 included, 53 (10.2%) @entity1 developed @entity410 within six hours after surgery. A total of 439 (84.4%) @entity1 received @entity7048 intraoperatively. There were no differences in baseline characteristics between the @entity1 who received @entity7048 compared with those who did not. The frequency of @entity410 did not significantly differ between @entity1 treated with @entity7048 versus other antibiotics (11.2% versus 4.9%, respectively; p = 0.08). Multivariable regression revealed that the use of @entity7048 did not increase the odds of having a @entity410 postoperatively compared with @entity1 treated with other antibiotics (odds ratio, 2.4; 95% confidence interval, 0.82-7.15). CONCLUSION: No relationship was found between the intraoperative use of @entity7048 and the development of @entity410 during the six hours after the repair of unruptured @entity438 .

Impact of intraoperative @entity7048 on postoperative XXXX after elective repair of @entity438 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures'] @entity7048 :: ('MESH:D002437', 'Chemical') :: ['cefazolin'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysm'] @entity438 :: ('MESH:D002532', 'Disease') :: ['unruptured cerebral aneurysm', 'cerebral aneurysms']
@entity410 :: (MESH:D012640,Disease) :: ['seizures']
