PURPOSE: This project sought to test the role of diet-related @entity32 in modulating the risk of @entity5 . METHODS: A nationwide population-based case-control study was conducted from 1 December 1994 through 31 December 1997 in Sweden. All newly diagnosed @entity1 with @entity420 of the oesophagus or gastroesophageal junction and a randomly selected half of @entity1 with @entity957 were eligible as cases. Using the Swedish Registry of the Total Population, the control group was randomly selected from the entire Swedish population and frequency-matched on age (within 10  years) and sex. The literature-derived dietary inflammatory index (DII) was developed to describe the inflammatory potential of diet. DII scores were computed based on a food frequency questionnaire. Higher DII scores indicate more pro-inflammatory diets. Odds ratios and 95  % confidence intervals (CI) were computed to assess risk associated between DII scores and @entity5 using logistic regression adjusted by potential confounders. RESULTS: In total, 189 oesophageal @entity420 , 262 gastroesophageal junctional @entity420 , 167 @entity957 , and 820 control subjects were recruited into the study. Significant associations with DII were observed for @entity957 (ORQuartile4vs1 4.35, 95  % CI 2.24, 8.43), @entity420 (ORQuartile4vs1 3.59, 95  % CI 1.87, 6.89), and gastroesophageal junctional @entity420 (ORQuartile4vs1 2.04, 95  % CI 1.24, 3.36). Significant trends across quartiles of DII were observed for all subtypes of @entity5 . CONCLUSIONS: Diet-related @entity32 appears to be associated with an increased risk of @entity5 , regardless of histological type.

Diet-related XXXX and @entity5 by histological type: a nationwide case-control study in Sweden.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity5 :: ('MESH:D009369', 'Disease') :: ['oesophageal cancer'] @entity957 :: ('MESH:D002294', 'Disease') :: ['oesophageal squamous cell carcinomas', 'oesophageal squamous cell carcinoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas', 'oesophageal adenocarcinoma', 'adenocarcinoma']
@entity32 :: (MESH:D007249,Disease) :: ['inflammation']
