AIMS: The use of intraoperative @entity461 monitoring (IOPTH) in combination with preoperative imaging has been useful to surgeons performing minimally invasive parathyroidectomy principally for adequacy of excision. However, its role within @entity1 with equivocal imaging remains less clear particularly regarding the reduction of bilateral neck explorations. This study investigated the influence of IOPTH monitoring on the type of surgical approach adopted for @entity1 with @entity459 ( @entity459 ). Specifically, determining its impact amongst @entity1 with equivocal imaging results. METHODS: 165 @entity1 undergoing parathyroidectomy for @entity459 at a single institution by a single surgeon, between 2008 and 2012, were included. @entity1 were divided into 2 groups, IOPTH monitoring and non-IOPTH monitoring. They were sub-classified according to their imaging strengths: strongly positive, equivocal and negative imaging. The percentages of @entity1 undergoing focused, unilateral and bilateral operations were determined. RESULTS: 108 @entity1 had IOPTH monitoring and 57 @entity1 did not based on the availability of IOPTH monitoring. @entity1 with strongly positive imaging had a higher frequency of focused operation in both groups; IOPTH 73.4% and non-IOPTH 71.4%. @entity1 with negative imaging results had a higher frequency of bilateral operations; IOPTH 77.8% and non-IOPTH 72.7%. In @entity1 with equivocal imaging results more focused/unilateral operations were performed with IOPTH monitoring 66.6% versus non-IOPTH 25%. The use of intraoperative @entity461 increased the likelihood of a unilateral procedure with equivocal imaging compared to those with negative imaging p  =  0.04. CONCLUSION: IOPTH monitoring is most useful as an adjunct to preoperative imaging when imaging results are equivocal allowing for more focused/unilateral operations to be performed.

Role of intraoperative XXXX monitoring and surgical approach in @entity459 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity459 :: ('MESH:D049950', 'Disease') :: ['primary hyperparathyroidism', 'PHPT'] @entity461 :: ('5741', 'Gene') :: ['PTH']
@entity461 :: (5741,Gene) :: ['PTH']
