This investigation summarizes and evaluates the results of a clinical protocol that we designed to care for @entity1 with @entity879 ( @entity879 ). Adult @entity1 with @entity879 were enrolled in the protocol. Grade II portal-systemic @entity75 prompted admission to the intensive care unit (ICU). @entity1 who met the clinical criterion were activated for liver transplantation. @entity428 ( @entity428 ) was monitored in @entity1 with grade III @entity75 . An increase in @entity428 was treated with hyperventilation, diuretics, barbiturates, or a combination thereof. Survival was considered to have occurred if the @entity1 left the hospital alive. Our series included 25 @entity1 . Orthotopic liver transplantation (OLT) was performed on 19 @entity1 , 12 of whom survived. Only 2 of 6 @entity1 who did not undergo transplantation survived. Ten of 11 @entity1 who underwent transplantation before reaching grade IV @entity75 survived. Only 2 of 8 @entity1 who underwent transplantation after reaching grade IV survived (P = .006). The causes of death included @entity2657 (3 @entity1 ), disseminated @entity2381 (3 @entity1 ), and other (5 @entity1 ). @entity428 was monitored in 11 @entity1 . Increased pressure was documented by seven of the monitors placed. There was one focal @entity548 secondary to a subdural monitor. Outcome is improved if transplantation occurs before grade IV @entity75 . @entity428 monitoring can be accomplished without significant risk of @entity548 . In our series, infection with @entity17555 occurred frequently and with fatal outcome.

XXXX : results of a 5-year clinical protocol.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity2657 :: ('MESH:D001929', 'Disease') :: ['cerebral edema'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity428 :: ('MESH:D019586', 'Disease') :: ['Intracranial pressure', 'ICP'] @entity75 :: ('MESH:D001927', 'Disease') :: ['encephalopathy'] @entity879 :: ('MESH:D017114', 'Disease') :: ['ALF', 'acute liver failure'] @entity17555 :: ('MESH:C535390', 'Disease') :: ['aspergillus'] @entity2381 :: ('MESH:D001228', 'Disease') :: ['aspergillosis']
@entity879 :: (MESH:D017114,Disease) :: ['Acute liver failure']
