BACKGROUND: Several approaches to minimize @entity282 , @entity390 , and enhance recovery are available for @entity1 undergoing mastectomy with immediate tissue expander (TE) reconstruction. We compared the effectiveness of intraoperative local infiltration of liposomal @entity1341 (LB) to preoperative @entity616 ( @entity616 ). METHODS: We retrospectively reviewed @entity1 who underwent mastectomy with immediate TE reconstruction between May 2012 and October 2014 and compared @entity1 with preoperative ultrasound-guided @entity616 to those with intraoperative LB infiltration. RESULTS: Fifty-three @entity1 (54.6  %) received LB and 44 received @entity616 . LB was associated with less opioid use in the recovery room (p  <  0.001), fewer patients requiring antiemetics (p  =  0.03), and lower day of surgery @entity158 scores (p  =  0.008). LB also was associated with longer time to first opioid use (p  =  0.04). On multivariable analysis controlling for expander placement location, year of surgery, and axillary lymph node dissection (ALND), the only variable that remained statistically significant was lower opioid use in the recovery room for @entity1 with LB (p  =  0.03) and day of surgery @entity158 scores approached significance (p  =  0.05). There was no difference in the proportion of @entity1 discharged within 36  h of surgery between the groups. Focusing on first cases of the day (where PVBs are performed in the OR) showed average time to skin incision was 15  min shorter in the LB group (p  =  0.004). CONCLUSIONS: Local infiltration of LB in @entity1 undergoing mastectomy with immediate TE reconstruction decreases narcotic requirements in the recovery room, shortens preoperative anesthesiology time, and provides similar, if not better, perioperative @entity158 control compared with @entity616 .

Comparative Study of Liposomal XXXX Versus Paravertebral Block for Pain Control Following Mastectomy with Immediate Tissue Expander Reconstruction.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity1341 :: ('MESH:D002045', 'Chemical') :: ['bupivacaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity616 :: ('MESH:D006327', 'Disease') :: ['paravertebral block', 'PVB']
@entity1341 :: (MESH:D002045,Chemical) :: ['Bupivacaine']
