BACKGROUND: Seventeen to 43% of @entity1 with non-cardiac @entity662 suffer from @entity148 / @entity4697 . Cognitive behavioural therapy (CBT) is effective in reducing non-cardiac @entity662 . However, no data are available indicating that @entity158 following CBT may be cognitively mediated or whether success of CBT is dependent on the presence of @entity4697 . The aim of the study was threefold: (1) does CBT have a differential effect on cognitive measures; (2) does a relationship exist between improvement in non-cardiac @entity662 and changes in cognitive measures, and (3) can @entity4697 be established as a moderator of the effect of treatment? METHODS: Sixty-five @entity1 with non-cardiac @entity662 completed a randomised trial comparing study CBT with 'care as usual'. Dependent measures were: frequency of @entity662 , @entity148 , the fear of bodily sensations, attributions and catastrophic cognitions. RESULTS: CBT had a differential effect on most of the cognitive measures. @entity158 reduction was associated with the development of more adequate cognitions with respect to @entity662 , independent of @entity148 . Although @entity4697 @entity1 reported higher baseline scores on the cognitive measures, no differences in treatment results were found between @entity4697 and no- @entity4697 @entity1 . CONCLUSIONS: @entity158 reduction following CBT may be cognitively mediated. The presence of @entity4697 did not affect the outcome of treatment, implying a broad applicability of the cognitive model for treatment of @entity1 with non-cardiac @entity662 .

Cognitive change following cognitive behavioural therapy for non-cardiac XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity4697 :: ('MESH:D016584', 'Disease') :: ['panic disorders', 'panic'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety', 'anxiety reduction'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain reduction', 'Pain']
@entity662 :: (MESH:D002637,Disease) :: ['chest pain']
