Secular trends in AMI rates were analyzed in relation to physical activity levels. The population attributable risk of physical inactivity was calculated. @entity1 were randomly selected subjects from a suburb of Copenhagen, Denmark, screened during the years 1964-1991. Occupational physical activity and in leisure time were assessed 1964, 1974, 1976, 1982, 1987 and 1991 by self-administered questionnaire along with smoking habits and @entity167 consumption. Blood pressure, weight, height and serum lipids were measured according to WHO-standards. Mortality data were obtained from death certificates, from hospital records or autopsies. Acute @entity583 (AMI) 1964-1994 were included. 13.925 @entity1 and @entity1 aged 30, 40, 50 and 60 years, were drawn as random samples from a background population of 300.000 inhabitants. A cohort born in 1914 was examined in 1964 and 1974, a cohort born in 1936, was examined in 1976 and 1987; Monica (Monitoring trends and determinants in @entity65 ) I cohort were examined in 1982 and 1987; MONICA II in 1986, and MONICA III in 1991. Mean physical activity level at leisure adjusted for age and sex increased over time (P < 0001). 25% of the @entity1 were sedentary, and more @entity1 reported a sedentary lifestyle than @entity1 . The overall trend was from 1964 to 1992 a decline in physical activity at work (P < 0001) in both gender and all age groups. The difference in AMI incidence rates between leisure time physical activity (LTPA) levels increased over time. No change was found in AMI rates comparing sedentary in different time periods. A remarkable decrease over time in the AMI incidence rate was found in physically active during leisure time. Population attributable risk (PAR) exceeded 40% in both genders in the late 1980s. In conclusion the difference in AMI rates between LTPA subgroups has increased over time. The low AMI rates observed among the most physically active reveal a substantial potential for the prevention of AMI through physical activity. A population attributable risk of more than 40% for physical inactivity suggests a potential for primary prevention through increased physical activity.

Secular trends in acute XXXX in relation to physical activity in the general Danish population.

@entity1 :: ('9606', 'Species') :: ['women', 'Participants', 'men'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarctions'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular diseases']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
