PURPOSE: To present a large series of @entity3193 treated with proton beam irradiation and to describe the treatment outcomes. METHODS: We treated 54 eyes of 53 @entity1 with @entity3193 . The lesions consisted of 48 circumscribed @entity2695 and six @entity2695 in @entity1 with @entity3932 . The total applied dose was 27.3 Gy in four eyes, 22.7 Gy in three eyes, and 16.4 Gy to 18.2 Gy in 47 eyes. RESULTS: The retina reattached within six months after treatment in all 54 eyes and no recurrence of the secondary @entity1713 occurred within the follow-up period of 6 months to 9 years. @entity5 treated with the higher doses regressed faster than @entity5 treated with the lower doses, but radiation-induced complications of the optic nerve appeared in all four eyes treated with a total dose of 27.3 Gy. Of 31 eyes treated with 16.4 to 18.2 Gy and followed for more than 1 year, 22 had an improvement in their visual acuity, and nine retained the same visual acuity. At the last follow-up examination, the best-corrected visual acuity was 20/20 or better in nine eyes, 20/40 to 20/25 in 13 eyes, 20/100 to 20/50 in six eyes, and 20/200 or less in three eyes. CONCLUSIONS: Proton beam irradiation of @entity3193 appears to be a valid therapeutic alternative. A total proton dose ranging from 16.4 to 18.2 Gy applied in four daily fractions seems adequate to ensure local control of both @entity5 and secondary @entity1713 .

Proton beam irradiation of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2695 :: ('MESH:D006391', 'Disease') :: ['diffuse hemangiomas', 'hemangiomas'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['retinal detachment'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumors', 'tumors'] @entity3932 :: ('MESH:D013341', 'Disease') :: ['Sturge-Weber syndrome'] @entity3193 :: ('MESH:D015862', 'Disease') :: ['choroidal hemangioma', 'choroidal hemangiomas']
@entity3193 :: (MESH:D015862,Disease) :: ['choroidal hemangiomas']
