UNASSIGNED: In the treatment of @entity15 ( @entity15 ), interferon beta ( @entity2391 ) applies. It rarely can lead to @entity879 ( @entity879 ). A 42-year-old female with @entity15 was admitted to the Department because of @entity1087 , @entity425 , drowsiness and @entity390 . Four weeks earlier, she had started therapy with @entity2391 -1a. Liver tests made prior to initiation of @entity2391 -1a were normal but on admission to the Department exceed several times the upper limit. @entity879 was recognized and @entity2391 -1a was immediately stopped. In the fourth day of hospitalization, symptoms of @entity99 have progressed. The @entity1 was transferred to the Department of Transplantation, where @entity5693 developed and three days later the orthotopic liver transplantation was performed. In histopathological picture of the removed liver extensive @entity39 and @entity82 dominated. Immunosuppressive therapy consisted of @entity1140 , @entity618 and tapering @entity229 . Within five years after surgery, there was no recurrence of symptoms of @entity15 and the transplanted organ is functioning properly. @entity879 is a rare complication of @entity2391 therapy but it can occur. The appearance of symptoms suggestive of @entity99 should prompt extension of diagnosis and, if necessary, discontinuation of therapy.

@entity879 and liver transplantation in a @entity1 with XXXX treated with interferon beta.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity5693 :: ('MESH:D006501', 'Disease') :: ['hepatic coma'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity879 :: ('MESH:D017114', 'Disease') :: ['ALF', 'acute liver failure'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity425 :: ('MESH:D018908', 'Disease') :: ['general weakness'] @entity618 :: ('MESH:C063008', 'Chemical') :: ['mycophenolate mofetil'] @entity2391 :: ('3456', 'Gene') :: ['IFNb'] @entity1140 :: ('MESH:D016559', 'Chemical') :: ['tacrolimus'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic encephalopathy', 'liver injury'] @entity15 :: ('MESH:D009103', 'Disease') :: ['MS', 'multiple sclerosis']
@entity15 :: (MESH:D009103,Disease) :: ['multiple sclerosis']
