BACKGROUND: ICDs can improve survival in LVAD recipients. However, the impact of cardiac resynchronization therapy (CRT-D) on outcomes in @entity1002 ( @entity1002 ) @entity1 is not known. We sought to determine if CRT-D improved clinical outcomes in @entity1002 @entity1 compared with an @entity1479 alone. METHODS AND RESULTS: Sixty-one consecutive @entity1002 @entity1 with an @entity1479 or CRT-D were evaluated. Impact of CRT-D on mortality, all-cause hospitalization, and incidence of @entity955 ( @entity955 ) and ventricular (VA) @entity943 post-LVAD implant was compared against @entity1 with an @entity1479 alone. Of the 61 LVAD @entity1 , 31 (59.8  16 years, 84% male) had CRT-D and 30 (57.2  13 years, 74% male) had an @entity1479 . Before LVAD implant, no significant differences were noted between the groups in demographic and clinical characteristics, LVAD indications, and incidence of @entity955 and VA. Over 682   45 days of LVAD support, 8 @entity1 (25.8%) died in the CRT-D arm vs. 5 (16.7%) in the @entity1479 arm (p=0.35). No differences were noted between the CRT-D and @entity1479 groups in all-cause (96.8 vs. 93.3%; p= 0.63) and HF hospitalizations (19.4 vs. 26.7%; p=0.78), left ventricular (LV) end-diastolic diameter (6.4  1.5 vs. 6.2  1.1 cm, p=0.47), incidence of @entity955 (35.4 vs. 33.3%; p=0.80), VA (29 vs. 26.6%; p=0.86) and @entity1479 shocks (22.6 vs.16.7%; p=0.93). Beta-blocker and antiarrhythmic drug use post-LVAD was similar in both groups. CONCLUSIONS: In @entity1 with refractory HF who received CF-LVADs, CRT-D, when compared to @entity1479 , did not significantly improve mortality, all-cause hospitalization, LV dimensions, and incidence of @entity955 and VA.

Impact of Cardiac Resynchronization Therapy on Clinical Outcomes in XXXX with Continuous Flow Left ventricular Assist Devices.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1479 :: ('OMIM:252500', 'Disease') :: ['ICD'] @entity955 :: ('MESH:D001281', 'Disease') :: ['AA', 'atrial'] @entity943 :: ('MESH:D001145', 'Disease') :: ['arrhythmias'] @entity1002 :: ('MESH:D018487', 'Disease') :: ['continuous flow left ventricular assist device', 'CF-LVAD']
@entity1 :: (9606,Species) :: ['Patients']
