BACKGROUND AND AIM: Scrambler Therapy is a novel neuromodulation that works by electrocutaneous stimulation in a non-invasive manner through C fibers surface receptors. It substitutes @entity158 information with synthetic "non @entity158 " information. The primary aim of this study was to analyze the efficacy and safety of Scrambler Therapy after ten sessions related to different usage conditions and different learning curves that occur in a multi-center study. METHODS: 201 @entity1 have been treated with Scrambler Therapy. All the @entity1 were suffering from @entity1118 with a mean @entity158 NRS of 7.41 (SD 2.06) before treatment. Main causes of @entity1118 : @entity9 18.40 %, chronic @entity1643 ( @entity1643 ) 37.31%, @entity305 10.94%, and @entity1897 14.42 %. The remaining 18.93 % included @entity1118 due to other causes. RESULTS: The difference between pre-treatment NRS 7.41 (SD 2.06) and post-treatment 1.60 (SD 2.22) was statistically significant (P< 0.0001). The mean number of sessions per @entity1 was 10, but 39 had complete absence of @entity158 sooner and used fewer sessions. Only 7 @entity1 stopped treatment due to lack of results, and 2 for personal reasons not ascribable to the treatment. Stimulation @entity158 score of 0 during treatment, and not just @entity158 reduction, predicts long term effectiveness, so this must be pursued by optimizing electrode positioning and correct fine-tuning of stimulation intensity. CONCLUSION: Scrambler Therapy is an efficient and safe alternative for several different types of refractory chronic @entity9 , with a very rare possibility of adverse events.

XXXX treatment and scrambler therapy: a multicenter retrospective analysis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1643 :: ('MESH:D017116', 'Disease') :: ['low back pain', 'LBP'] @entity305 :: ('MESH:D011115', 'Disease') :: ['polyneuropathy'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral neuropathy'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1118 :: ('MESH:D059350', 'Disease') :: ['chronic pain'] @entity9 :: ('MESH:D009437', 'Disease') :: ['neuropathic pain', 'post herpetic neuralgia']
@entity1118 :: (MESH:D059350,Disease) :: ['Chronic pain']
