UNASSIGNED: There is a substantial prevalence of post-operative incisional @entity547 for both laparoscopic and laparotomy procedures, but there have been few attempts at quantifying abdominal wound closure methodology in the literature. One method to ascertain a more robust method of wound closure is the identification of the influence of suture placement parameters on suture pullout force. Current surgical practice involves a recommended @entity8976 and bite separation of 10mm, but the evidence base for this is not clear. In this paper, the suture pullout characteristics of both porcine and @entity1 linea alba were investigated to ascertain a suture placement protocol for surgical wound closure. Uniaxial suture pullout force testing on fresh frozen porcine and @entity1 linea alba samples was performed using standard materials testing machines. The influence of the number of suture loops, the @entity8976 and the bite separation of the sutures and the orientation of the sutures with respect to the principal fibre direction in the linea alba were assessed. Results showed a clearly identifiable relationship between pullout force of the suture, bite separation and @entity8976 , with low suture separation and high suture depth as optimal parameters for increasing pullout force. Resistance to pullout could be improved by as much as 290% when optimizing test conditions. Both @entity1 and porcine tissue were observed to exhibit very similar pullout force characteristics, corroborating the use of a porcine model for investigations into wound closure methodology. Orientation of suture application was also found to significantly affect the magnitude of suture pullout, with suturing applied longitudinally across a transverse defect resulting in higher pullout forces for small suture bite separations. Although further assessment in an environment more representative of in vivo conditions is required, these findings indicate that increasing the @entity8976 and reducing the bite separation with respect to the current surgical recommendations may reduce the risk of post-operative incisional @entity547 .

The suture pullout characteristics of XXXX and porcine linea alba.

@entity1 :: ('9606', 'Species') :: ['human'] @entity8976 :: ('MESH:D001733', 'Disease') :: ['bite depth'] @entity547 :: ('MESH:D006547', 'Disease') :: ['hernia']
@entity1 :: (9606,Species) :: ['human']
