PURPOSE: To evaluate the individual contributions of pigment colorant and packing solution containing @entity4280 ( @entity12468 ) on the @entity26 permeability (Dk) of a cosmetic printed etafilcon A daily disposable contact lens packaged with @entity12468 . METHOD: The @entity26 transport of a contact lens is evaluated through the central optical zone of the lens. Cosmetic printed contact lenses contain pigment colorant in the periphery or mid-periphery of the lens. Therefore, to assess the impact of cosmetic print on @entity26 permeability, special lenses need to be produced that contain the colorant within the central optical zone. This technique was used to obtain multiple measurements of nonedge-corrected Dk/t of both the center pigmented lens and its nonpigmented equivalent, using a polarographic measurement described in International Organization for Standardization ( @entity8670 ) 18369-4:2006(E), and the Dk derived for each measurement is corrected for edge effect. In addition, the edge-corrected Dk values of lenses made from the same monomer batch were measured. The lenses were packaged and autoclaved with and without proprietary technology which embeds @entity12468 in the contact lens during autoclaving. The resulting Dk value of the printed lens material was then used with thickness data to generate true Dk/t profiles for a given lens power. RESULTS: The edge-corrected Dk of the printed etafilcon A lens with offset pigment colorant was measured to be 19.7*10(-11) (cm(2)/s) (mL O2/mL  mmHg) at 35  C. This was within   20% tolerance range as specified in @entity8670 18369-2:2012(E) for the edge-corrected Dk of the nonpigmented etafilcon A control lens evaluated during the same session, 19.5*10(-11) (cm(2)/s) (mL O2/mL  mmHg). The edge-corrected Dk values of the lenses packaged with @entity12468 (mean 20.1, standard deviation [SD] 0.3) were also within the   20% tolerance range compared to those packaged without @entity12468 (mean 20.0, SD 0.3). CONCLUSION: The pigment colorant and @entity12468 embedded in the contact lens during autoclaving were not found to influence the @entity26 permeability of the etafilcon A material.

XXXX permeability of the pigmented material used in cosmetic daily disposable contact lenses.

@entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity12468 :: ('CHEBI:53245', 'Chemical') :: ['PVP'] @entity4280 :: ('MESH:D011205', 'Chemical') :: ['polyvinyl pyrrolidone'] @entity8670 :: ('D007545', 'Chemical') :: ['ISO']
@entity26 :: (MESH:D010100,Chemical) :: ['Oxygen']
