AIM: The extension rate of @entity4272 in Western countries has been reported, but no data regarding the, long-term follow up, have been described for the Japanese population. Additionally, @entity1 with long-standing or extensive @entity31 ( @entity31 ) have an increased risk for developing @entity14 . This study evaluated both the disease extension rate and the @entity5 development among @entity1 with an initial diagnosis of @entity1066 . METHOD: We retrospectively investigated the medical charts of @entity1 with @entity4272 from 1979 to 2014. The primary focus of this research was the extension of the inflammatory area. The secondary focus included risk factors for disease extension and the development of @entity5 . RESULTS: Sixty-six @entity1 satisfied the inclusion criteria. Proximal extension of the disease occurred in 34 @entity1 : 19 @entity1 had left-sided @entity1960 and15 had pancolitis. According to a multivariate analysis, disease extension was significantly higher in @entity1 who had their disease onset before 25 years of age (P value = 0.043). The cumulative rate of disease extension at 10 and 20 years were 33.8% and 52.2%, respectively. Three @entity1 were diagnosed with @entity1141 during the follow-up; all of whom experienced disease extension before the development of @entity1141 . CONCLUSION: The rate of disease extension of @entity31 in the Japanese population was comparable to that in Western countries. A younger onset of the disease was associated with disease extension. Extension of @entity4272 may be associated with an increased risk of @entity14 . This article is protected by copyright. All rights reserved.

Clinical patterns and progression of XXXX in the Japanese population: A retrospective study of incidence and risk factors influencing progression.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['neoplasia'] @entity4272 :: ('MESH:D011349', 'Disease') :: ['proctitis'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcerative proctitis'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity1960 :: ('MESH:D003092', 'Disease') :: ['colitis'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasia']
@entity1066 :: (MESH:D014456,Disease) :: ['ulcerative proctitis']
