BACKGROUND: The prognostic role of @entity5707 and renal function in elderly @entity101 @entity1 has been so far scarcely investigated. AIMS: We assessed the impact of left ventricular geometry and renal function on 24h-Holter electrocardiogram (ECG) recordings and outcome in elderly @entity101 @entity1 . METHODS: We enrolled 251 asymptomatic @entity101 elderly @entity1 (>65year-old). @entity5707 was evaluated by 2-D echocardiogram. Lown's class, mean QTc and standard deviation of all normal R-R intervals (SDNN) were assessed by 24-h Holter-ECG recordings. Data on all-cause and cardiovascular mortality were collected for 2years. RESULTS: Mean age was 76.2  11.4years. High Lown's classes were more frequently observed in the presence of @entity4346 ( @entity4346 ) (57.3% vs. 23.7%; p<0.001). Mean QTc was 444.8  34.8ms and resulted directly correlated with indexed left ventricular mass (r=0.228; p=0.001). @entity1 with @entity740 ( @entity740 ) showed lower SDNN as compared with those with preserved renal function (92.02  36.11ms vs. 103.84  33.96ms, respectively; p=0.017). At 2years, all-cause and cardiovascular mortality rates were 38.0% and 21.1%, respectively. @entity6 (HR: 2.40; 95% C.I.1.16 to 4.99; p=0.019), @entity740 (HR: 2.22; 95% C.I.1.10 to 4.52; p=0.028), prolonged QTc (HR: 2.18; 95% C.I.1.07 to 4.41; p=0.030) and SDNN<96ms (HR: 1.98; 95% C.I.1.03 to 4.13; p=0.048) were independent predictors of @entity65 at 2year follow-up. CONCLUSIONS: @entity740 and @entity5707 predicted altered ventricular batmotropism. @entity6 , @entity740 , heart rate variability and QTc are important predictors of @entity65 in elderly @entity101 @entity1 .

Impact of XXXX and renal function on 24h-ECG recordings and cardiovascular outcome in elderly @entity101 @entity1 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'Diabetes mellitus'] @entity740 :: ('MESH:D051436', 'Disease') :: ['CKD', 'Chronic Kidney Disease'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['LVH', 'left ventricular hypertrophy'] @entity5707 :: ('MESH:D020257', 'Disease') :: ['Left ventricular remodeling', 'left ventricular remodeling'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular death']
@entity5707 :: (MESH:D020257,Disease) :: ['left ventricular remodeling']
