This research report studies several biochemical and histochemical aspects of @entity2622 and explores their use in follow-up of @entity1 undergoing radiotherapy. Material came from 19 @entity1 with @entity189 admitted to Kenyatta National Hospital. A control group consisted of 20 @entity1 matched for age who attended clinics at the hospital but were not suffering from any @entity5 ; control tissue for histological examination was obtained from 3 @entity1 who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in @entity1 with @entity2622 show an increase in alkaline phosphatase in @entity3909 tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between @entity1 and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of @entity5 tissue. 1 section containing normal tissue bordering @entity3909 tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the @entity5 tissue. In summary, there is increased enzyme activity around the @entity5 areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in @entity3909 tissue and normal tissue, which may be of value in follow-up care.

A clinical, biochemical and histochemical study of XXXX as seen at the Kenyatta National Hospital.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignant disease'] @entity2622 :: ('MESH:D002583', 'Disease') :: ['cervical carcinoma'] @entity3909 :: ('MESH:D055756', 'Disease') :: ['carcinomatous'] @entity189 :: ('MESH:D002277', 'Disease') :: ['invasive cervical carcinoma']
@entity189 :: (MESH:D002277,Disease) :: ['carcinoma of the cervix']
