Background @entity6962 , also known as spindle cell @entity189 , are rare and highly aggressive @entity5 characterized by dual histologic differentiation of squamous cell and mesenchymal cell @entity5 . Occurrence of @entity6962 in maxillary sinus is very rare, with only 11 cases reported since 1957. The small number of reported cases creates an obstacle to the increased understanding of the behavior, prognosis, and therapeutic management of this @entity5 . Case Report A 52-year-old @entity1 presented with a 2-month history of right nasal obstruction. Computed tomography (CT) and magnetic resonance imaging (MRI) showed opacified right frontal, sphenoid, ethmoid, and maxillary sinuses with soft tissue density and expansion of the mass with erosion of the right lateral maxillary wall. Functional endoscopic sinus surgery (FESS) was done and histopathology revealed @entity1949 lined by stratified hyperplastic squamous epithelium with an increased degree of @entity1141 and pleomorphism and a second spindle cell high-grade @entity5 with bizarre giant cells and abnormal mitotic figures. Consistent with @entity6962 , immunohistochemistry showed strong positive staining for @entity2277 in the spindle cell component and strong positive staining for cytokeratin markers in the epithelial cell component. The @entity1 underwent right total maxillectomy with postoperative chemoradiation therapy and survived for 1 year. Conclusions @entity6962 sinus is a rare disease with non-specific symptoms; it usually presents in the advance stage and is associated with poor @entity1 prognosis. This case indicates that surgical intervention with postoperative chemoradiotherapy improves @entity1 prognosis and should be considered as the standard therapeutic modality.

Management of spindle cell XXXX of the maxillary sinus: a case report and literature review.

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity1949 :: ('MESH:D012892', 'Disease') :: ['multiple fragments of nasal mucosa'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'neoplastic growth', 'tumors'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasia'] @entity2277 :: ('7431', 'Gene') :: ['vimentin'] @entity6962 :: ('MESH:D002296', 'Disease') :: ['Carcinosarcomas', 'Carcinosarcoma of the maxillary', 'carcinosarcoma']
@entity189 :: (MESH:D002277,Disease) :: ['carcinoma']
