BACKGROUND: @entity157 ( @entity157 ) commonly develops in @entity1 with @entity3619 . Intrahepatic recurrence after hepatectomy often includes nodules of new @entity5 in the liver remnant. The aim of this study was to examine @entity99 -related factors that might predict this type of recurrence. METHODS: The influence of various @entity99 -related factors on intrahepatic recurrence of @entity157 was studied by multivariate analysis in 138 @entity1 who underwent curative resection and were followed for more than 2 years. RESULTS: The Cox proportional hazard model showed that histological evidence of @entity82 of the underlying liver was the most significant predictive factor for intrahepatic recurrence (P = 0.001). Serum @entity2313 level was also significantly associated with recurrence (P = 0.038). The relative risks of histological @entity82 and low serum @entity2313 levels were 8.9 and 1.7 respectively. Among @entity5 -related factors, only @entity5 size was significantly associated with recurrence (P = 0.017). Major hepatectomy was also an independent risk factor for intrahepatic recurrence (P = 0.004). CONCLUSION: Histological evidence of @entity82 and low serum @entity2313 levels are useful predictors of intrahepatic recurrence after hepatectomy, presumably owing to @entity5 in the liver remnant.

Liver XXXX increases the risk of intrahepatic recurrence after hepatectomy for @entity157 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2313 :: ('213', 'Gene') :: ['albumin'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['metachronous multifocal tumour', 'tumour'] @entity3619 :: ('MESH:D006521', 'Disease') :: ['chronic hepatitis'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'Hepatocellular carcinoma'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatitis']
@entity82 :: (MESH:D005355,Disease) :: ['fibrosis']
