OBJECTIVE: We tested the primary hypothesis that surgical site infections (SSIs) are more common in @entity1 who had longer periods of intraoperative low blood pressure. Our secondary hypothesis was that hospitalization is prolonged in @entity1 experiencing longer periods of critically low systolic blood pressure (SBP) and/or mean arterial pressure (MAP). BACKGROUND: @entity551 compromises local tissue perfusion, thereby reducing tissue oxygenation. @entity551 might thus be expected to promote @entity281 , but the extent to which low blood pressure contributes remains unclear. METHODS: We considered @entity1 who had colorectal surgery lasting at least 1 hour at the Cleveland Clinic between 2009 and 2013. The duration of @entity551 exposure and development of SSI was assessed with logistic regression; the association between @entity551 exposure and duration of hospitalization was assessed with Cox proportional hazard regression. RESULTS: A total of 2521 @entity1 were eligible for analysis. There was no adjusted association between SBP @entity551 <80mm Hg and SSI, with an estimated odds ratio (95% confidence interval) of 0.97 (0.81, 1.17) per 5-minute increase in SBP @entity551 (P = 0.54). There was also no adjusted association between @entity551 time and SSI, with estimated odds ratio of 0.97 (0.81, 1.17) for a 5-minute increase in @entity551 <55mm Hg time (P = 0.71). There was no association between duration of @entity551 and time to discharge. CONCLUSIONS: Intraoperative @entity551 does not seem to be a clinically important predictor of SSI after colorectal surgery, probably because the outcomes are overwhelmingly determined by other baseline and surgical factors-and perhaps @entity551 .

Association Between Intraoperative Low Blood Pressure and Development of XXXX After Colorectal Surgery: A Retrospective Cohort Study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity551 :: ('MESH:D007022', 'Disease') :: ['MAP hypotension', 'hypotensive', 'Hypotension', 'hypotension', 'postoperative hypotension']
@entity281 :: (MESH:D007239,Disease) :: ['Surgical Site Infection']
