BACKGROUND: We analyzed a database from our hospital comprised of 31 cases of primary @entity0 (PBL) that included treatment and follow-up information during the past 30 years, and investigated the correlation between microvessel density (MVD) and survival in @entity1 with PBL. @entity1 AND METHODS: We reviewed all @entity1 diagnosed with primary @entity0 from June 1977 to March 2007. @entity1 demographics such as survival, recurrence, and time to follow-up were recorded, in addition to surgical, radiation, and/or chemotherapy treatment(s). We also assessed microvessel density (MVD) in the pretreatment breast lump of 31 previously untreated @entity1 using a- @entity2280 immunohistochemical staining. RESULTS: All 31 @entity1 were female ranging in age from 37 years to 75 years. Diffuse large @entity1892 was the most common histologic diagnosis. According to the staging of Wiseman and Liao, 17 @entity1 (55%) were stage IE, and 14 @entity1 (45%) were stage IIE. Treatment that included radiation therapy in stage I @entity1 (node negative) improve the survival rate and lowered the recurrence rates. Treatment that included chemotherapy in stage II @entity1 (node positive) showed benefits in terms of higher survival rate and lower recurrence rate. Increasing microvessel density is a weak but statistically significant predictor of lower survival overall. CONCLUSION: Nodal status predicts the outcome and guides the use of radiation and chemotherapy. There is no statistical difference between the different types of operative methods. @entity1 with high MVD measured in the microenvironment had worse survival overall than PBL @entity1 with low expression.

Analysis of 31 cases of primary XXXX : the effect of nodal involvement and microvascular density.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS', 'Patient'] @entity2280 :: ('947', 'Gene') :: ['CD34'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['B-cell lymphoma'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast lymphoma']
@entity0 :: (MESH:D001943,Disease) :: ['breast lymphoma']
