Paraneoplastic @entity2801 antibodies may occur concurrent with the diagnosis or at various times after diagnosis and treatment of @entity5 . Between 2002 and 2009, we observed two @entity1 with acquired @entity447 due to an @entity2801 auto-antibody, which appeared 4 and 5 months after uncomplicated @entity5 surgery. We aimed to evaluate if such an association of @entity5 surgery and @entity2801 antibody formation has been observed previously. We retrieved all published case reports of @entity5 -associated @entity2801 auto-antibodies from PubMed for the period 1950-2010. The search in the literature revealed 13 @entity1 in whom a @entity2801 inhibitor developed after uncomplicated surgery for @entity5 and a bleeding-free time interval of up to 6 months; 11/15 @entity1 had @entity5 (five @entity694 , four @entity5 and @entity189 one each). The median time period between surgery and antibody detection was 3 months (1 week-6 months). In most cases, the antibody titre was low (median: 14 BU mL     , range: 1.7-64 BU mL     ). Immunosuppressive treatment was successful in most of the cases - nine of the treated @entity1 reached a sustained CR of the antibody after a median time of 3 months. Postoperative paraneoplastic @entity2801 inhibitors may be regarded as a special, not yet recognized subgroup of acquired @entity2801 antibodies. They share some characteristics with postpartum @entity2801 inhibitors with regard to the latency period between the triggering event and the appearance of the antibody, and between the usually low antibody titres and their good response to immunosuppressive treatment.

Postoperative paraneoplastic factor VIII auto-antibodies in XXXX with solid @entity5 .

@entity2801 :: ('2157', 'Gene') :: ['FVIII'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity447 :: ('MESH:D006467', 'Disease') :: ['haemophilia A'] @entity5 :: ('MESH:D009369', 'Disease') :: ['abdominal cancers', 'pancreatic cancer, gastric cancer', 'cancer'] @entity189 :: ('MESH:D002277', 'Disease') :: ['choledochus carcinoma'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer']
@entity1 :: (9606,Species) :: ['patients']
