BACKGROUND: No series have described the surgical pathology of subaortic septal myectomy in @entity1 with conditions other than @entity1121 ( @entity1121 ). METHODS: Medical records and microscopic slides were reviewed from 98 non- @entity1121 @entity1 undergoing septal myectomy at Mayo Clinic Rochester from 1996 to 2000. Concurrently, 204 other @entity1 had myectomy for @entity1121 . RESULTS: The study group (65 @entity1 , 33 @entity1 ) ranged in age from 1.5 to 92 years (mean, 61). Seventy underwent surgery for @entity472 (Group 1), 25 for @entity475 (Group 2) and 3 for other conditions (Group 3). Group 1 @entity1 were older than Group 2 @entity1 (72 vs. 26 years; P<.0001). Microscopic evaluation showed myocyte @entity1184 (97%), vacuolization (35%), left bundle branch tissue (26%) (33% in Group 1 vs. 8% in Group 2; P=.02) and disarray (19%); interstitial @entity82 (92%), @entity32 (10%) and @entity2783 (7%, all prealbumin type, all Group 1, >80 years old); arterial thickening (18%) and @entity1141 (12%), and dilated venules (6%); and @entity82 (74%) (64% in Group 1 vs. 100% in Group 2; P=.0001) and @entity32 (17%). CONCLUSIONS: Of 302 @entity1 undergoing subaortic septal myectomy, 32% had conditions other than @entity1121 . Myocyte disarray was present in 19% of @entity1 without @entity1121 (and was absent in 21% of @entity1121 @entity1 in a companion study). Thus, disarray alone cannot be used reliably to include or exclude a diagnosis of @entity1121 in small surgical specimens. Because amyloid was found unexpectedly in seven elderly @entity1 , we recommend routine amyloid staining on surgical myectomy tissue from @entity1 >/=65 years old.

Surgical pathology of subaortic septal myectomy not associated with XXXX : a study of 98 cases (1996-2000).

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity32 :: ('MESH:D007249', 'Disease') :: ['chronic inflammation', 'inflammation'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis', 'endocardial fibrosis'] @entity2783 :: ('MESH:D000686', 'Disease') :: ['amyloidosis'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['hypertrophy'] @entity475 :: ('MESH:C564793', 'Disease') :: ['congenital subaortic stenosis'] @entity472 :: ('MESH:D001024', 'Disease') :: ['aortic stenosis'] @entity1121 :: ('MESH:D002312', 'Disease') :: ['HCM', 'hypertrophic cardiomyopathy'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasia']
@entity1121 :: (MESH:D002312,Disease) :: ['hypertrophic cardiomyopathy']
