BACKGROUND: Although @entity6475 ( @entity6475 ) is known to be reduced in @entity1 with @entity1121 ( @entity1121 ), it has not been elucidated whether or not @entity6475 ( @entity6475 ) is reduced. We aimed to determine whether multidirectional and layer-specific @entity296 is reduced in @entity1 with nonobstructive @entity1121 .Methods   and   Results:Speckle-tracking echocardiography was performed in 41 @entity1121 @entity1 and 27 control subjects. @entity1347 and @entity6475 were measured in the inner, mid, and outer layers. Global @entity6475 was significantly lower in the @entity1121 group than in controls in the inner (-10.3  2.9 vs. -14.8  2.0%, P<0.001), mid (-8.7  2.6 vs. -13.8  1.9%, P<0.001), and outer (-7.2  2.6 vs. -11.9  1.9%, P<0.001) layers. Global @entity6475 was preserved in the inner layer (-23.8  4.7 vs. -24.3  3.3%, P=0.69) but reduced in the mid (-10.3  3.1 vs. -13.3  2.5%, P<0.001) and outer layers (-6.7  2.3 vs. -8.6  2.3%, P=0.002). Differences in @entity6475 between the inner and outer layers correlated with segmental relative wall thickness (r=-0.20, P=0.002). Furthermore, only the absolute value of global @entity6475 in the inner layer positively correlated with left ventricular ejection fraction (r=0.32, P<0.01) among these multidirectional and layer-specific strains. CONCLUSIONS: In @entity1 with @entity1121 , not only the @entity6475 in all layers but also @entity6475 in the mid and outer layers was reduced, presumably reflecting @entity296 . In contrast, @entity6475 in the inner layer was preserved, being associated with maintenance of chamber function. (Circ J 2015; 79: 2471-2479).

Myocardial Shortening in 3 Orthogonal Directions and Its Transmural Variation in XXXX With Nonobstructive @entity1121 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity296 :: ('MESH:D009202', 'Disease') :: ['impaired myocardial function', 'myocardial strain'] @entity1347 :: ('MESH:C537775', 'Disease') :: ['Segmental and global LS'] @entity6475 :: ('MESH:D013180', 'Disease') :: ['CS', 'longitudinal strain', 'LS', 'circumferential strain'] @entity1121 :: ('MESH:D002312', 'Disease') :: ['HCM', 'hypertrophic cardiomyopathy']
@entity1 :: (9606,Species) :: ['Patients']
