BACKGROUND: The study was carried out to evaluate the effect of low-dose radiation therapy in @entity1 with age-related @entity1020 . METHODS: One hundred eyes of 78 @entity1 (mean age 72 years) with different forms of age-related @entity1020 were treated with external beam radiotherapy between 1971 and 1989. In four fractions a total dose of 2 Gy was administered over 7 days. Radiation therapy was performed by the conventional 200-kV technique. The mean duration of follow-up period was 7 years (range 0.5 to 20 years). A control group was composed of 96 eyes from @entity1 with @entity13785 who received no therapy. The mean visual acuity at first presentation and the duration of follow-up was the same as in the treatment group. RESULTS: No difference in visual acuity between the treatment and control groups could be observed. After 1, 2, 5 and 10 years the mean visual acuity was equal in the radiation group and the control group. Even in subgroup analysis regarding only the eyes with exudative forms of @entity13785 , no effect of this treatment strategy could be demonstrated. CONCLUSION: Our results suggest that low-dose radiation therapy in @entity1 with age-related @entity1020 has no beneficial effect. However, it must be considered that the dose of 2 Gy is low in comparison to doses used in recently published studies (5-24 Gy).

Low-dose radiation therapy for age-related XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1020 :: ('MESH:D008268', 'Disease') :: ['macular degeneration'] @entity13785 :: ('MESH:D006009', 'Disease') :: ['AMD']
@entity1020 :: (MESH:D008268,Disease) :: ['macular degeneration']
