UNASSIGNED: e292 Background: This is a pilot study update on the potential of MET to up-regulate @entity17940 gene expression correlated with the up-regulation @entity876 gene expression in @entity1 diagnosed with @entity0 . METHODS: The selection process for the study @entity1 was nonrandom. The following was the eligibility criteria. 1.) Inclusion Criteria: Breast Cancer, Stages II, III. 2.) Exclusion Criteria: Cognitively impaired, weak or ill. The study utilized two groups. Each group was assigned two research @entity1 . Group One received one session of MET. Group Two received two sessions of MET. Each MET session was approximately 25-35 minutes in duration. Blood samples were taken at baseline and post-MET sessions to provide evidence in gene expression changes. For Group Two, the post-MET session blood draw was done 7 days after baseline. 1.) Primary Endpoint: To determine whether MET can up-regulate @entity17940 gene expression. 2.) Secondary Endpoint:To determine whether there is a correlation between up-regulated @entity17940 gene expression and up-regulated @entity876 gene expression. The blood samples were sent to genomics labs at the Childrens Hospital of Los Angeles and the University of Nevada Las Vegas for mRNA extraction and microarray analysis. The gene expression was measured by DNA microarray results using the "PrimeView gene chip" and "Partek Genomics Suite" statistical software. RESULTS: For three @entity1 , there was no statistical or biologically significant up-regulation in @entity17940 gene expression. However, one @entity1 from Group 1 evidenced a biologically significant up-regulation of @entity17940 gene expression along with a biologically significant up-regulation of @entity876 gene expression. One major limitation of these findings is the statistical insignificance of the results due to the small number of @entity1 . CONCLUSIONS: This pilot study evidenced the up-regulation of @entity17940 gene expression potentially due to MET and provided evidence supporting the established correlation between @entity876 and @entity17940 gene expression that could induce apoptosis. This study also provided a foundation for a larger study with more @entity1 .

Mind-body medicine epigenetic technique (MET) and XXXX gene expression.

@entity876 :: ('7157', 'Gene') :: ['TP53'] @entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'participant'] @entity17940 :: ('63970', 'Gene') :: ['TP53AIP1'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer']
@entity17940 :: (63970,Gene) :: ['TP53AIP1']
