Deep brain stimulation (DBS) of the ventral intermediate thalamic nucleus ( @entity2277 ) has been recently introduced by Benabid and his colleagues as a new surgical procedure in the treatment of @entity191 ( @entity191 ). The advantage of DBS @entity2277 over lesioning (thalamotomy) is its reversibility and adjustability with the same clinical effect, but without the need to make a @entity9479 . In this procedure high-frequency stimulation is employed to simulate a thalamic lesion using an implanted electrode connected to a subcutaneously placed neuropacemaker. Four @entity1 with @entity400 -dominant @entity191 were included in the study. There were 3 @entity1 and one @entity1 . Three stimulators were implanted in the left and one in the right cerebral hemisphere. The @entity1 were evaluated using clinical scales, before and up to 24 months after surgery. Adverse effects associated with chronic @entity2277 stimulation were mild and reversible. Chronic thalamic stimulation is effective for drug-resistance parkinsonian @entity400 suppression, with few adverse side-effects. The method results in a significant improvement of function.

[Deep brain stimulation of the @entity2277 nucleus of the thalamus in the treatment of parkinsonian XXXX ].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity191 :: ('MESH:D010300', 'Disease') :: ["tremor-dominant Parkinson's disease", 'PD'] @entity9479 :: ('MESH:D013786', 'Disease') :: ['destructive thalamic lesion'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity2277 :: ('7431', 'Gene') :: ['Vim']
@entity400 :: (MESH:D014202,Disease) :: ['tremor']
