BACKGROUND: @entity146 is a characterized by rapid attachment loss, @entity79 and @entity1423 . Platelet-rich plasma (PRP) has been proposed to promote regeneration of the lost periodontal tissues. The aim of this study was to evaluate and compare the efficacy of PRP combined with hydroxyapatite (HA) graft in the treatment of @entity4297 in @entity146 ( @entity146 ) @entity1 . MATERIALS AND METHODS: Ten @entity146 @entity1 having bilateral intra-bony defect >= 2 mm and @entity92 ( @entity92 ) >= 6 mm were randomly treated either with the PRP/HA graft or HA graft alone. The clinical (plaque control record, @entity548 on probing index, @entity92 , and relative attachment level [RAL]), and radiographic parameters (size of the @entity79 ) were recorded pre- and post-operatively at 3, 6, and 12 months. RESULTS: After 12 months, for both maxillary and mandibular arches, the mean @entity92 decrease was significantly more (P < 0.05) for the test group than the control group (3.2 mm vs. 1.9 mm and 3.6 mm vs. 1.9 mm, respectively). Furthermore, the mean RAL decrease in both maxillary and mandibular arches was significantly more (P < 0.05) for the test group than the control group (3.0 mm vs. 1.2 mm and 3.1 mm vs. 1.4 mm, respectively). Radiographically, the test group showed significantly more defect fill as compared with the control group. CONCLUSION: Both treatments provided significant improvements in clinical and radiographic parameters in a 12-month postoperative period. PRP/HA group presented superior results regarding @entity92 , clinical @entity1017 and radiographic bone fill than HA group.

Clinical and radiographic evaluation of @entity4297 in XXXX @entity1 with platelet rich plasma/hydroxyapatite graft: A comparative controlled clinical trial.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity1423 :: ('MESH:D001791', 'Disease') :: ['familial aggregation'] @entity146 :: ('MESH:D001523', 'Disease') :: ['Aggressive periodontitis', 'localized aggressive periodontitis', 'L-AgP'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone destruction', 'bone defect'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['attachment gain'] @entity92 :: ('MESH:D007222', 'Disease') :: ['PD', 'PD reduction', 'probing depth'] @entity4297 :: ('MESH:D006330', 'Disease') :: ['intra-bony defects']
@entity146 :: (MESH:D001523,Disease) :: ['localized aggressive periodontitis']
