OBJECTIVE: To assess the relationship between @entity443 and 18 other hormonal and metabolic parameters in well characterized, normally cycling premenopausal @entity1 . DESIGN: Cross-sectional study. SETTING: University general clinical research center. SUBJECT(S): A total of 319 young healthy @entity1 with ovulatory menstrual cycles. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Midfollicular serum @entity443 concentrations. RESULT(S): In our final linear regression model, @entity443 was negatively associated with bioavailable T and positively associated with @entity1254 , associations that were independent from other parameters. @entity443 was also positively associated with @entity19517 , but only when taking into account confounding variables. Unexpectedly, there was no straightforward relationship between @entity443 and insulin resistance according to homeostasis-model assessment. CONCLUSION(S): Our results highlight the link between @entity342 action, as reflected by bioavailable T, and circulating @entity443 concentrations in all premenopausal @entity1 and speak to the importance of the relationship between @entity443 and @entity1254 , which is at least in part independent from @entity342 action. CLINICAL TRIAL REGISTRATION NUMBER: NCT00393172.

Cross-sectional study of factors influencing sex hormone-binding globulin concentrations in normally cycling premenopausal XXXX .

@entity1 :: ('9606', 'Species') :: ['women'] @entity19517 :: ('MESH:C017296', 'Chemical') :: ['estrone sulfate'] @entity1254 :: ('9370', 'Gene') :: ['adiponectin'] @entity342 :: ('CHEBI:50113', 'Chemical') :: ['androgen'] @entity443 :: ('6462', 'Gene') :: ['SHBG']
@entity1 :: (9606,Species) :: ['women']
