OBJECTIVE: To examine the association between sleep patterns (sleep duration and @entity22 ) and total and regional @entity79 ( @entity79 ) among older Boston Puerto Rican adults. MATERIALS/METHODS: We conducted a cross-sectional study including 750 Puerto Rican adults, aged 47-79 y living in Massachusetts. @entity79 at 3 hip sites and the lumbar spine were measured using dual-energy X-ray absorptiometry. Sleep duration ( <=5 h, 6 h, 7 h, 8 h, or >= 9 h/d) and @entity22 (difficulty initiating sleep, difficulty maintaining sleep, early-morning awaking, and @entity25 ) were assessed by a questionnaire. Multivariable regression was used to examine sex-specific associations between sleep duration, @entity22 and @entity79 adjusting for standard confounders and covariates. RESULTS: @entity1 who slept >= 9h/d had significantly lower femoral neck @entity79 , relative to those reporting 8 h/d sleep, after adjusting for age, education level, smoking, physical activity, depressive symptomatology, comorbidity and serum @entity560 concentration. This association was attenuated and lost significance after further adjustment for urinary @entity701 and serum inflammation biomarkers. In contrast, the association between sleep duration and @entity79 was not significant in @entity1 . Further, we did not find any significant associations between @entity22 and @entity79 in @entity1 or @entity1 . CONCLUSIONS: Our study does not support the hypothesis that @entity25 and @entity22 are associated with lower @entity79 levels in older adults. However, our results should be interpreted with caution. Future studies with larger sample size, objective assessment of sleep pattern, and prospective design are needed before a conclusion regarding sleep and @entity79 can be reached.

Association between Sleep Duration, XXXX Symptoms and Bone Mineral Density in Older Boston Puerto Rican Adults.

@entity1 :: ('9606', 'Species') :: ['women', 'Men', 'men'] @entity22 :: ('MESH:D007319', 'Disease') :: ['insomnia symptoms'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity701 :: ('MESH:D006854', 'Chemical') :: ['cortisol'] @entity25 :: ('MESH:D012893', 'Disease') :: ['non-restorative sleep', 'shorter sleep duration'] @entity560 :: ('MESH:D014807', 'Chemical') :: ['vitamin D']
@entity22 :: (MESH:D007319,Disease) :: ['Insomnia']
