UNASSIGNED: Single- @entity4334 polymorphisms in microRNAs are related to the occurrence, development and prognosis of @entity5 . The aim of the present study is to investigate the possible influence of the @entity21635 ( @entity31066 ) polymorphism on the risk of @entity356 in Chinese population. A total of 363 GC @entity1 and 969 @entity5 -free controls were enrolled in this study. The genotypes were obtained using MassARRAY method. The results showed that, compared with T allele, C allele was associated with a significantly increased risk of GC (OR=1.491, 95% CI=1.155-1.923, P=0.002). Moreover, a significantly increased risk of GC in subjects with the TC genotype was observed (adjusted OR of 1.559, 95% CI=1.148-2.117, P=0.004), compared with the wide type TT. We also found that basically dominant model (TT vs. TC+CC) was suitable for the association between @entity68585 and the risk of GC (OR=1.568, 95% CI=1.173-2.097, P=0.002). However, the same association was also shown in males and females. Meanwhile, @entity31066 was associated with the @entity5 size of GC @entity1 . The present study indicated that @entity21635 @entity31066 might contribute to GC risk and this SNP could be developed as a biomarker for GC prediction.

Association between microRNA-499 polymorphism and XXXX risk in Chinese population.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity31066 :: ('rs3746444', 'SNP') :: ['rs3746444'] @entity21635 :: ('574501', 'Gene') :: ['miR-499'] @entity68585 :: ('rs6513497', 'SNP') :: ['rs6513497'] @entity4334 :: ('D009711', 'Chemical') :: ['nucleotide'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
