CONCLUSION: Upper airway surgery is associated with salutary effects on the @entity1003 characteristics of OSA @entity1 , a benefit that may be protective against cardiac and cerebrovascular morbidity and mortality. OBJECTIVE: Increased @entity1003 is an important factor linking OSA and @entity65 . Surgery is an important method to treat OSA, but the effect of surgery on @entity1003 in OSA @entity1 is unknown. METHODS: the authors performed a prospective clinical trial of adult OSA @entity1 who underwent surgery from 2012-2014. Pre-operative and post-operative @entity1003 parameters and polysomnography (PSG) results were compared. RESULT: There were 61 subjects. The total rate of success in curing OSA was 11.5%. The rate of response after surgery was 40.8%. Overall, the @entity27 ( @entity27 ) improved after surgery (from 39.8 3        24.49 to 25.9 7        18.53, p   <   0.01). After surgery, serum platelet counts (PLT) decreased (from 242.5        52.6 to 230.9        40.7, p=0.01), and @entity2002 ( @entity2002 ) levels declined (from 262.5        52.5 to 247.3        44.4, p   =   0.02). Other @entity1003 parameters also improved: prothrombin time (PT) (from 10.6 2        0.62 to 10.8 6        0.70, p=0.01), activated partial thromboplastin time (APTT) (from 26.9 8        4.94 to 27.7 8        3.02, p   =   0.06), and @entity556 time (TT) (from 19.5 3        0.84 to 20.1 1        1.31, p   <   0.01).

Can upper airway surgery for OSA protect against XXXX via effects on coagulation?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2002 :: ('2244', 'Gene') :: ['Fibrinogen', 'FIB'] @entity556 :: ('2147', 'Gene') :: ['Thrombin'] @entity27 :: ('MESH:D020181', 'Disease') :: ['Apnea-Hypopnea Index', 'AHI'] @entity1003 :: ('MESH:D001778', 'Disease') :: ['blood coagulation'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular complications']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular sequelae']
