PURPOSE: To investigate the clinical manifestations and surgical results after vitrectomy for proliferative @entity6 (PDR) in young @entity1 . METHODS: Clinical features of @entity1 between 18 to 40  years old who received vitrectomy for PDR between January 2009 and January 2015 were retrospectively reviewed. Those older than 40  years who received vitrectomy for PDR during the same period were retrospectively enrolled and compared as the control group. RESULTS: There were 68 eyes (52 @entity1 ) in the study group and 77 eyes (61 @entity1 ) in the control group. The average age at operation was 33.15        4.92  years and 56.67        7.52  years, respectively (p   <   0.001). At presentation, those in the study group had significantly higher proportions of active fibrovascular proliferation and traction @entity1713 , and with significantly higher-severity gradings than those in the control group. After operation, the recurrent detachment rates were 13.2% in the study group and 1.3% in the control group (p   =   0.006), and the final anatomical success rates were 91.2% in the study group and 100% in the control group (p   =   0.009). The most significant risk factor for poor visual outcome in the study group was @entity2297 ( @entity2297 ) (p   =   0.001). @entity1 with Type 1 and @entity6 subgroups shared similar clinical features and visual outcome. CONCLUSIONS: Younger @entity1 who received vitrectomy for PDR presented with more severe anatomical features at the time of vitrectomy and had a higher rate of post-operative recurrent detachment. More than 90% achieved final anatomical success. @entity2297 was associated with worse visual outcome.

Vitrectomy for complications of proliferative XXXX in young adults: clinical features and surgical outcomes.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2297 :: ('MESH:D015355', 'Disease') :: ['NVG', 'neovascular glaucoma'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['retinal detachment'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Type 2 diabetes mellitus', 'diabetic retinopathy']
@entity6 :: (MESH:D003920,Disease) :: ['diabetic retinopathy']
