@entity9463 alligatoris was the suspected etiology of an epidemic of @entity697 which emerged in captive @entity20085 ( @entity20085 ) in Florida (USA) in 1995. In an experimental inoculation study conducted from April through October 1999, 18 alligators were inoculated with 10(2), 10(4), or 10(6) colony forming units (CFU) of M. alligatoris by instillation into the glottis. As early as 1 wk post-inoculation (PI), @entity9463 were cultured from blood of three of six alligators inoculated with 10(6) CFU. Two of those died and the third was euthanatized within 4 wk PI. Necropsy gross findings included fibrinous @entity827 and @entity625 . Histopathologic changes in affected individuals included @entity3126 , @entity401 , @entity2396 , @entity2401 , @entity693 , and @entity603 . @entity9463 were cultured quantitatively in high numbers from @entity825 , lung, coelomic cavity, liver, spleen, interior of pericardial sac, heart, blood, brain, and limb joints. In alligators inoculated with 10(6) CFU, heterophilia and moderate @entity4854 peaked about 4 wk PI, and seroconversion occurred by 6 to 8 wk PI. Necropsy gross and histologic findings were generally unremarkable for the surviving alligators inoculated with 10(6) CFU, alligators inoculated with 10(2) or 10(4) CFU, and four uninoculated control alligators. @entity9463 were not cultured at any time point from those alligators. The findings confirm that M. alligatoris can cause fulminant @entity32 and rapid death of alligators.

Pathology of experimental mycoplasmosis in XXXX .

@entity825 :: ('MESH:D055090', 'Disease') :: ['trachea'] @entity9463 :: ('MESH:D009175', 'Disease') :: ['mycoplasma', 'Mycoplasma'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammatory disease'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute multisystemic inflammatory disease'] @entity625 :: ('MESH:D001168', 'Disease') :: ['polyarthritis'] @entity827 :: ('MESH:D010505', 'Disease') :: ['polyserositis'] @entity3126 :: ('MESH:D011654', 'Disease') :: ['pulmonary edema'] @entity20085 :: ('8496', 'Species') :: ['Alligator mississippiensis', 'American alligators'] @entity2396 :: ('MESH:D010493', 'Disease') :: ['pericarditis'] @entity603 :: ('MESH:D013585', 'Disease') :: ['synovitis'] @entity693 :: ('MESH:D008581', 'Disease') :: ['meningitis'] @entity401 :: ('MESH:D017563', 'Disease') :: ['interstitial pneumonia'] @entity2401 :: ('MESH:D009205', 'Disease') :: ['myocarditis'] @entity4854 :: ('MESH:D006943', 'Disease') :: ['hyperglycemia']
@entity20085 :: (8496,Species) :: ['American alligators']
