@entity1 with extensive @entity5 involving the femur often require total femoral replacement when their limbs can be salvaged. Reported series are small and involve @entity5 . We present nine @entity1 with @entity421 of the femur treated at our institution between 2003 and 2010 with a mean follow-up of 27 (6 to 56) months. Their ages ranged from 9 to 17 (mean 14 years). They had large @entity5 (mean 911 cm3) and presented late with a mean of 5.5 months from the onset of symptoms to definitive treatment. All @entity1 underwent resection and total femur replacement. Six @entity1 have died and two are alive with good function at the time of this report. One was lost to follow-up. These @entity1 require a high level of treatment care and have a guarded prognosis. KEY WORDS: Large @entity421 , femur, total femoral replacement.

Large XXXX of the femur treated with total femoral replacement.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity421 :: ('MESH:D012516', 'Disease') :: ['osteosarcomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['volume tumours', 'heterogeneity of tumours', 'malignancies']
@entity421 :: (MESH:D012516,Disease) :: ['volume osteosarcomas']
