The gap in mortality between @entity1 with @entity309 ( @entity309 ) and the general population (1.5-3.0 fold risk) is increasing. This disparity is attributable mainly to @entity65 ( @entity65 ), as the @entity65 risk is comparable to @entity1 with @entity6 . The purpose of this study is to determine whether borage seed oil rich in @entity18943 , fish oil rich in @entity7784 ( @entity8393 ) and @entity4600 ( @entity4601 ), or the combination of both oils are useful treatments for @entity2299 in @entity1 with @entity309 . We randomized @entity1 into a double blind, 18 month trial. Mixed effects models were used to compare trends over time in serum lipids. No significant differences were observed between the three groups: All three treatment groups exhibited similar meaningful improvement in the lipid profile at 9 and 18 months. When all groups were combined, these treatments significantly reduced total and LDL- @entity165 and @entity1674 , increased HDL- @entity165 , and improved the atherogenic index. All improvements observed at 9 months persisted at 18 months (P < 0.001 verses baseline). Conclusion. Marine and botanical oils may be useful treatment for @entity309 @entity1 who are at increased risk for @entity65 compared to the general population.

Treatment of XXXX with marine and botanical oils: influence on serum lipids.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity7784 :: ('MESH:D015118', 'Chemical') :: ['eicosapentaenoic acid'] @entity8393 :: ('CHEBI:28364', 'Chemical') :: ['EPA'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity4600 :: ('CHEBI:28125', 'Chemical') :: ['docosahexaenoic acid'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity4601 :: ('CHEBI:16016', 'Chemical') :: ['DHA'] @entity18943 :: ('MESH:D017965', 'Chemical') :: ['gamma-linolenic acid'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity309 :: (MESH:D001172,Disease) :: ['rheumatoid arthritis']
