OBJECTIVE: Presentation of 5 clinical cases of Merkel cell @entity189 , highlighting the clinical, histopathological, management, and monitoring features. Review of related literature. METHODS: Retrospective review of clinical records and telephone interview of the 5 @entity1 treated for @entity3852 between 2006 and 2013, in the Orbit and Oculoplastic Department, Clinical Hospital of the University of Chile. RESULTS: Five @entity1 (2 @entity1 , 3 @entity1 ); 79.2 years (range 64-94 years), with a mean onset of 10 weeks (range 5-16 weeks), @entity5 size reaching a mean of 2.5*2*2.1cm at the time of surgery. Described as a nodular mass, exophytic, solid, reddish coloured. With no infiltrated lymph nodes or @entity3 in the first match. Staging as T2N0M0, after the first surgery with oncological criteria. Two lymph node recurrences detected during monitoring. Distant @entity3 was found in one @entity1 . The histopathological diagnosis was confirmed by immunohistochemical study of the biopsy. The surgical strategy was full excision, control of surgical margins in the intraoperative period, and eyelid reconstruction with Hughes flap, @entity16557 or primary closure, depending on the case. CONCLUSIONS: Early diagnosis, wide excision of the @entity5 with intraoperative control of clear margins with conventional or Mohs surgery, and proper eyelid reconstruction are adequate for a good survival in elderly @entity1 with this @entity5 . The study of sentinel lymph node biopsy in primary intervention is recommended; with subsequent radiotherapy to decrease the recurrence and increase survival.

Merkel cell XXXX . A series of 5 cases and review of the literature.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity3852 :: ('MESH:D015266', 'Disease') :: ['Merkel cell carcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour', 'eyelid tumour'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma of the eyelid'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity16557 :: ('MESH:C536013', 'Disease') :: ['Cutler/Beard flap']
@entity189 :: (MESH:D002277,Disease) :: ['carcinoma of the eyelid']
