This paper examines the spread of @entity2953 from the Opening of Korea to the early Japanese colonial period. It focuses on the formation and expansion of Japanese settlement in Korea, the influence of wars, and the state control of VD. The Opening of Korea made the foreign settlement, and Japanese licensed prostitution flourished in Japanese settlement. According to the First Annual Report of the Korean Government Hospital (1886) and Gyelimuisa (1887), VD @entity1 occupied 18.3% of outpatients in Jejungwon hospital of Seoul and 8.9% of outpatients in Busan hospital. Directly after the Opening of Korea, Korean @entity1 's VD became lesser critical than Japanese @entity1 's VD. But the expansion of Japanese settlement and outbreak of two wars such as Sino-Japanese War and Russo-Japanese War made worse Korean @entity1 's VD. According to the Residency-General resources (1904-1909), @entity1065 @entity1 was registered in 0.8-6.6% (average 3.6%). If it add to @entity2954 and @entity27739 @entity1 which often could not be found out by the naked eyes, the number of VD @entity1 will be increase. Ji Seok-yeong (1855-1935), the earliest @entity14333 vaccinarian in Korea, asserted the need of VD control. Though he warned @entity1 bought sex as well as prostitutes became the main culprit of VD diffusion, he supported licensed prostitution because of realistic possibility. The Great Han Empire (1897-1910) tried to control the lower grade whore, and gathered prostitutes in some area by police power. After Japanese annexation of Korea, while Japanese has gradually decreased in VD @entity1 , Korean has gradually increased in VD @entity1 .

[Trade, wars and the XXXX : VD epidemic and control of Korea in the late nineteenth and early twentieth century].

@entity1 :: ('9606', 'Species') :: ['patients', 'people', 'men'] @entity2954 :: ('MESH:D006069', 'Disease') :: ['gonorrhea'] @entity2953 :: ('MESH:D012749', 'Disease') :: ['venereal disease'] @entity27739 :: ('MESH:D002602', 'Disease') :: ['chancroid'] @entity14333 :: ('10255', 'Species') :: ['smallpox'] @entity1065 :: ('MESH:D013587', 'Disease') :: ['syphilis']
@entity2953 :: (MESH:D012749,Disease) :: ['venereal disease']
