BACKGROUND AND PURPOSE: To relieve the @entity158 and @entity147 experienced by @entity1 who undergo high-dose-rate intracavitary radiotherapy (HDR-ICRT) for @entity5 and to improve the current status of gynecologic brachytherapy in Japan, a new intravenous anesthetic protocol involving the administration of a combination of @entity1875 and @entity3652 was developed. The primary aim of this study is to investigate the efficacy and safety of this new anesthetic protocol during @entity5 . METHODS AND MATERIALS: All the @entity1 who were diagnosed with @entity5 between December 2008 and February 2011, treated with three-channel brachytherapy and subjected to the new sedation protocol, were evaluated. A visual analog scale (VAS) was used to assess the @entity158 during brachytherapy, and we collected VAS score at the next HDR-ICRT. @entity137 were graded using the Common @entity137 Criteria, version  3. RESULTS: A total of 178 sessions of HDR-ICRT were delivered to 57 @entity1 . The @entity1 ' median VAS @entity158 score was 0 (range, 0-10). The most frequent side effect was Grade 1-2 @entity390 , which occurred in 33 sessions (34%). However, 13 of 14 @entity1 received concurrent @entity900 chemotherapy. None of the @entity1 experienced Grade 3 or 4 adverse events. CONCLUSIONS: We have demonstrated that our new intravenous anesthetic protocol produces appropriate effects and can be performed by radiation oncologists who were required to finish training in basic life support and the cooperative system of emergency according to in-house guideline.

New approach to relieving @entity158 and XXXX during high-dose-rate intracavitary irradiation for @entity5 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity137 :: ('MESH:D064420', 'Disease') :: ['Toxicity', 'Toxicities'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity5 :: ('MESH:D009369', 'Disease') :: ['HDR-ICRT for cervical cancer', 'cervical cancer'] @entity900 :: ('MESH:D002945', 'Chemical') :: ['cisplatin'] @entity147 :: ('MESH:D005316', 'Disease') :: ['distress'] @entity3652 :: ('MESH:D007649', 'Chemical') :: ['ketamine'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity147 :: (MESH:D005316,Disease) :: ['distress']
