The number and topographic localization of spontaneously occurring mitotic figures were studied in 22 @entity428 of the stomach. The lesions were divided into 3 equally thick zones. Mitoses occurred in 5 of 7 slight @entity1141 , in 7 of 8 moderate @entity1141 , and in all 7 severe @entity1141 . When present, mitoses were localized to the superficial zone in slight, moderate and severe @entity1141 , in the middle zone in some moderate @entity1141 , and in almost all severe @entity1141 . In the deeper zone, mitoses were seen in one of the moderate @entity1141 and in as much as 5 of the severe @entity1141 . The number of mitoses were significantly higher in moderate and severe @entity1141 , when compared to slight @entity1141 . The percentage of atypical mitoses increased gradually from 27% in slight @entity1141 to 41% in moderate, and 52% in severe @entity1141 . In the adjacent, @entity356 , a 1.5% of atypical mitoses was found. Significantly higher amounts of atypical mitoses were recorded in severe @entity1141 , as compared to slight and moderate @entity1141 . The results suggest that the various types of @entity428 (slight, moderate and severe) of the stomach may be distinguished, not only by the characteristics of the atypical cells in interphase--as is the case today--but also by the topographic distribution of mitoses and by the difference in percentage of atypical mitoses occurring in these lesions. The possible significance of the mitosis as a biohistological marker of the behaviour of @entity428 of the stomach is discussed.

Atypical mitoses in XXXX of the stomach.

@entity356 :: ('MESH:D013274', 'Disease') :: ['non-dysplastic gastric mucosa'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasias', 'dysplasia'] @entity428 :: ('MESH:D019586', 'Disease') :: ['elevated dysplasias']
@entity428 :: (MESH:D019586,Disease) :: ['elevated dysplasias']
