Two cases of @entity1121 with @entity1184 and high defibrillation threshold (DFT) are described. A 14-year-old @entity1 , whose single risk factor for @entity944 was extreme @entity1184 with maximum interventricular septum (IVS) thickness of 43 mm, survived an episode of @entity2224 . During @entity1479 implantation DFT testing showed energy requirements >30 J and the procedure was aborted. @entity2643 and @entity1855 treatment was discontinued and treatment with oral @entity2778 was instituted. After a period of @entity2643 washout the procedure was repeated and DFT of 24 J was encountered. An 18-year-old female with @entity1184 (IVS thickness=35 mm) and other risk factors for @entity944 underwent @entity1479 implantation for primary prevention. During the procedure DFT=20 J and @entity1479 with 30 J maximal output was implanted. An increase in DFT to more than 20 J was encountered during pre-discharge test. Lack of 10 J safety margin warranted @entity1479 system revision and upgrade; during the second procedure DFT was 24 J and @entity1479 with 35 J maximal output was implanted. In summary, in both cases ICDs with 35 J maximal output were successfully implanted.

[Massive myocardial hypertrophy in XXXX : a risk factor for @entity944 and high defibrillation threshold during cardioverter-defibrillator implantation].

@entity1 :: ('9606', 'Species') :: ['boy'] @entity1479 :: ('OMIM:252500', 'Disease') :: ['ICD'] @entity2643 :: ('MESH:D000638', 'Chemical') :: ['amiodarone', 'Amiodarone'] @entity944 :: ('MESH:D003645', 'Disease') :: ['sudden death'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['massive hypertrophy', 'hypertrophy'] @entity1855 :: ('MESH:D014700', 'Chemical') :: ['verapamil'] @entity2778 :: ('MESH:D013015', 'Chemical') :: ['sotalol'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['ventricular fibrillation'] @entity1121 :: ('MESH:D002312', 'Disease') :: ['hypertrophic cardiomyopathy']
@entity1121 :: (MESH:D002312,Disease) :: ['hypertrophic cardiomyopathy']
