@entity27 ( @entity27 ) is a common disorder with numerous potential sequelae. Although the majority of these consequences can be reduced with appropriate treatment, only limited data exist regarding the natural @entity74 in untreated individuals. We hereby report a long-term follow-up of all untreated @entity1 (n = 40) followed-up in the Technion Sleep Clinic, using both subjective and objective measurements. In addition, we report a long-term follow-up of 11 @entity1 who attempted dietary @entity353 . The average time interval between the first and second polysomnographies for the untreated group was 5.0 +/- 2.8 yrs, and 2.5 +/- 2.3 yrs for the weight reduction group. There was no significant change in Body Mass Index (BMI) or @entity1576 ( @entity1576 ) between the two Polysomnographic (PSG) evaluations in the untreated @entity1 . However, eight @entity1 developed @entity101 (n=5) or @entity299 ( @entity299 ) (n=3) between the two evaluations. @entity1576 , age and BMI at the time ofthe initial evaluation were not predictive of changes in @entity1576 , snoring intensity or minimal @entity26 saturation. However, the @entity1 who developed @entity101 / @entity299 had significantly higher @entity1576 than the @entity1 who did not (46 +/- 27 vs. 23 +/- 17 h(-1), P < 0.005). In the weight-loss group, BMI decreased by a mean of 3.1 kg m(-2), and @entity1576 decreased by 20events h(-1), P<0.05 for both. There was a significant correlation between the @entity353 and improvement in @entity1576 (R = 0.75, P = 0.005). We conclude that in @entity27 @entity1 @entity1576 does not necessarily increase over time, but associated @entity101 or @entity299 may develop. When @entity353 is successfully achieved, @entity25 significantly improves with a high correlation between the extent of @entity353 and the improvement in apnoea status.

Long-term follow-up of untreated XXXX with @entity25 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity27 :: ('MESH:D020181', 'Disease') :: ['untreated obstructive sleep apnoea', 'Obstructive sleep apnoea', 'OSA'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['RDI', 'Respiratory Disturbance Index'] @entity74 :: ('MESH:D030342', 'Disease') :: ['progression ofthis disorder'] @entity299 :: ('MESH:D006331', 'Disease') :: ['ischaemic heart disease', 'IHD'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep apnoea']
@entity1 :: (9606,Species) :: ['patients']
