" NlmCategory=: Diagnosis and treatment of @entity884 ( @entity884 ) is still a challenge for physicians. Group of @entity1 with the worst prognosis is treated in Intensive Cardiac Care Unit (ICCU). Etiologic agent can not be identified in a substantial number of @entity1 . AIM: The aim of study is to find differences between @entity1 with blood culture negative @entity884 (BCNIE) and blood culture positive @entity884 (BCPIE) treated in ICCU by comparing their clinical course and laboratory parameters. MATERIALS AND METHODS: Retrospective analysis of 30 @entity1 with @entity884 hospitalized in ICCU Swietokrzyskie Cardiac Centre between 2010 and 2016. This group consist of 26 @entity1 (86,67%) and 4 @entity1 (13,3%). Mean age was 58 years   13. Most of the cases were new disease, recurrence of the disease was observed in 2 cases (6,7%). 8 @entity1 (26,7%) required artificial ventilation, 11 (36,7%) received inotropes and 6 (20%) vasopresors. In 14 (46,7%) cases blood cultures was negative (BCNIE), the rest of @entity1 (16, 53,3%) was @entity884 ( @entity884 ). RESULTS: Both of the groups were clinically similar. There were no statistically significant differences in incidence of cardiac implants, localization of bacterial vegetations, administered @entity2661 , antibiotic therapy, artificial ventilation, surgical treatment, complication and in-hospital mortality. Incidence of @entity299 in all of BCNIE cases and in 81,3% cases of BCPIE draws attention, but it is not statistically significant difference (p=0,08). There was statistically significant difference in mean BNP blood concentration (3005,17 ng/ml   2045,2 vs 1013,42 ng/ml   1087,6; p=0,01), but there were no statistically significant differences in rest of laboratory parameters. CONCLUSIONS: BCNIE group has got higher mean BNP blood concentration than BCPIE group. There were no statistically significant differences between these groups in others laboratory parameters, clinical course and administered antibiotic therapy. In our endemic region major cause of BCNIE seems to be early antibiotic therapy prior to collection of blood samples, but further studies are necessary.

[ XXXX in intensive cardiac care unit - clinical and biochemical differences of blood-culture negative @entity884 ].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity2661 :: ('MESH:D002395', 'Chemical') :: ['catecholamines'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac complications'] @entity884 :: ('MESH:D004696', 'Disease') :: ['IE', 'infective endocarditis', 'BCIE', 'blood cultures - positive infective endocarditis']
@entity884 :: (MESH:D004696,Disease) :: ['Infective endocarditis']
