@entity30 ( @entity30 ) is a disease characterized by acute @entity32 at diagnosis which evolves toward a more fistulizing and @entity66 phenotype over time. This leads to a high risk of bowel resections and ultimately short bowel with @entity294 and @entity8884 , which represents a major part of the burden inflicted by @entity30 . Bowel-conserving endoscopic and surgical procedures have therefore been developed. Specific antifibrotic medical therapies are currently lacking. Through-the-scope @entity384 has been described in several cohorts as an alternative to surgical resection or stricturoplasty in selected @entity1 . Efficacy of @entity384 is high, with an immediate success rate of 78% (between 73 and 100%), defined as the ability to pass with the scope through the stricture. However, symptomatic recurrence is frequent, with need for new dilatation in 41% and need for surgery in 42%, with a mean interval of 15 months. Adjunctive techniques such as local @entity134 or anti- @entity310 injections or stenting have not been conclusively proven to be of added benefit. We usually reserve @entity384 for @entity1 with short strictures (<5 cm) and nonpenetrating disease, preferably at the ileocolonic @entity254 . Similar to other interventions in endoscopy, @entity384 has an intrinsic risk of complications which can be estimated at 2%. Balloon size and @entity1 selection can serve to increase safety.    2014 S. Karger AG, Basel.

Endoscopic and medical management of fibrostenotic XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity66 :: ('MESH:D004194', 'Disease') :: ['fibrostenotic disease'] @entity8884 :: ('MESH:D008286', 'Disease') :: ['malabsorption'] @entity310 :: ('7124', 'Gene') :: ['TNF'] @entity384 :: ('MESH:D002311', 'Disease') :: ['endoscopic dilation', 'endoscopic balloon dilation'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['steroid'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"]
@entity30 :: (MESH:D003424,Disease) :: ['Crohn's disease']
