BACKGROUND: @entity2791 ( @entity2791 ) is a relatively uncommon but potentially reversible cause of @entity177 . In a previous report, we demonstrated that the presence of @entity2791 is independently associated with mortality in a group of @entity1 undergoing coronary angiography. Our current study expands on this cohort, investigating the effect of the severity of @entity2791 on all-cause mortality. METHODS: A total of 3987 @entity1 underwent abdominal aortography immediately following coronary angiography. For the purpose of survival analysis, significant @entity2791 was defined as > or =75% narrowing in the luminal diameter. RESULTS: Significant @entity2791 was present in 4.8% of @entity1 studied and was bilateral in 0.8%. Factors associated with the presence of @entity2791 included female gender, older age, @entity101 , @entity712 , elevated serum @entity1011 , and @entity712 . The four-year unadjusted survivals for @entity1 with and without significant @entity2791 were 57 and 89%, respectively (P < 0.001). Using the Cox proportional hazards model, the factors independently associated with decreased survival were the presence of @entity2791 , increased age, the severity of @entity453 , the presence of comorbid disease, reduced ejection fraction, symptoms of @entity712 , and the mode of treatment of @entity453 . In the multivariate model, the presence of @entity2791 conferred a hazard ratio of 2.01 (95% CI, 1.51 to 2.67, P < 0.001). We demonstrated an incremental effect on mortality according to the severity of @entity2791 at baseline. Four-year adjusted survival for @entity1 with 50%, 75%, and > or =95% stenosis was 70%, 68%, and 48%, respectively. In addition, bilateral disease was associated with four-year survival of 47% as compared with 59% for @entity1 with unilateral disease (P < 0.001). The impact of @entity2791 on survival remained robust regardless of the manner of treatment of @entity453 [that is, medical, percutaneous transluminal coronary angioplasty (PTCA), or coronary artery bypass graft (CABG)]. CONCLUSIONS: In this @entity1 population, the presence of @entity2791 is a strong independent predictor of mortality. Increasing severity of @entity2791 has an incremental effect on survival probability.

Severity of renal vascular disease predicts mortality in XXXX undergoing coronary angiography.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity712 :: ('MESH:D006333', 'Disease') :: ['congestive heart failure', 'congestive cardiac failure'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity2791 :: ('MESH:D012078', 'Disease') :: ['Renal artery stenosis', 'RAS'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease']
@entity1 :: (9606,Species) :: ['patients']
