AIM: To describe the pattern of upper airway (UA) obstruction during drug-induced sedation endoscopy (DISE) and to evaluate the outcome of DISE-directed treatment. METHODS: Prospective study of DISE in surgically @entity27 ( @entity27 ) @entity1 without syndromic comorbidity or @entity2122 . Treatment was individually tailored according to UA findings during DISE and polysomnographic data. Reported values are median (lower-upper quartile). RESULTS: Thirty-seven @entity1 aged 4.1 years (2.1-6.0), with body mass index z-score 0.3 (-0.9 to 0.9), and obstructive @entity27 index (oAHI) 9.0/h (6.1-19.3) were included. @entity3885 was found in 33 cases (89%) as an isolated entity or as part of a multi-level obstruction. These @entity1 were treated with adenotonsillectomy (n   =   28), adenoidectomy (n   =   3), or tonsillectomy (n   =   2). The remaining four @entity1 received non-surgical treatment. Pre-postoperative polysomnographic data in 22 @entity1 showed a significant improvement in oAHI from 8.6/h (6.7-20.7) to 1.0/h (0.6-2.0) (P   =   0.001). Only two of these 22 @entity1 had residual @entity27 (oAHI   >=    5/h), indicating a success rate of 91%. CONCLUSIONS: Based on UA findings during DISE, a non-surgical treatment was proposed for 11% of @entity1 . A 91% success rate was obtained in those treated with (adeno)tonsillectomy. These data suggest that DISE may be helpful to identify @entity1 most likely to benefit from UA surgery.

Drug-induced sedation endoscopy in XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity2122 :: ('MESH:D019465', 'Disease') :: ['craniofacial abnormalities'] @entity27 :: ('MESH:D020181', 'Disease') :: ['OSAS', 'apnea-hypopnea', 'naive obstructive sleep apnea syndrome'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['Adenotonsillar obstruction']
@entity27 :: (MESH:D020181,Disease) :: ['pediatric obstructive sleep apnea syndrome']
