STUDY OBJECTIVES: To evaluate the histocompatibility of four different materials used to cover expandable metallic stents. DESIGN: Prospective, randomized, unblinded study. SETTING: Animal research laboratory of Kurume University. @entity1 OR @entity1 : Twenty 12- to 18-kg mongrel @entity235 . INTERVENTIONS: Handmade Gianturco-type stents with six bends, 20 mm in length, and 15 to 20 mm in diameter were covered using four different materials: @entity7502 mesh, @entity1346 -coated mesh, @entity2635 mesh, and ePTFE. Covered stents were inserted into the @entity825 after i.v. anesthesia. Five animals were used in each group. MEASUREMENTS AND RESULTS: Postinsertion status was observed using clinical and bronchoscopy measures 7, 14, 28, and 56 days after intervention. Eight weeks after stent insertion, the tracheal specimens were studied pathologically. A scoring system was used to evaluate the histocompatibility of covered stents in each study group. The mean of clinical scores in the @entity7502 group was 1.84+/-0.36, which was significantly higher than those in the groups of @entity1346 , @entity2635 , and ePTFE. The means of histopathologic scores in the @entity7502 group and the @entity1346 group were 1.60+/-0.55, which were significantly higher than those in groups of @entity2635 and ePTFE. CONCLUSIONS: @entity7502 mesh cover was more suitable than @entity1346 -coated mesh, @entity2635 mesh, and ePTFE because of its excellent histocompatibility.

Experimental study of the histocompatibility of covered expandable metallic stents in the XXXX .

@entity1 :: ('9606', 'Species') :: ['PATIENTS', 'PARTICIPANTS'] @entity825 :: ('MESH:D055090', 'Disease') :: ['trachea'] @entity235 :: ('9615', 'Species') :: ['dogs'] @entity7502 :: ('MESH:D011126', 'Chemical') :: ['Polypropylene', 'polypropylene'] @entity1346 :: ('MESH:D012828', 'Chemical') :: ['silicone'] @entity2635 :: ('CHEBI:60160', 'Chemical') :: ['polyester']
@entity825 :: (MESH:D055090,Disease) :: ['trachea']
