AIMS: The aim of this study was to assess prospectively the effectiveness and safety of a new version of the dedicated bifurcation BiOSS stent, the @entity3446 -eluting BiOSS @entity18282 , for the treatment of distal left main (LM) stenosis. METHODS AND RESULTS: This was a prospective international registry which enrolled @entity1 with NSTE-ACS or stable @entity951 . Provisional T-stenting was the mandated strategy. The primary endpoint was the cumulative rate of @entity204 , @entity583 ( @entity583 ) and @entity75 revascularisation (TLR) at 12 months. Twelve-month quantitative coronary angiography endpoints included late lumen loss and percent diameter stenosis. A total of 74 @entity1 with @entity850 were enrolled. Seventy-three of the 74 @entity1 (aged 67  9 years, 23% @entity1 , 20.3% NSTE-ACS, SYNTAX score 22.4  4.4) were successfully treated with the BiOSS @entity18282 stent, with additional side branch placement of regular DES in 11 @entity1 (14.9%). Periprocedural @entity583 occurred in one (1.4%) @entity1 . The 12-month MACE rate was 9.5% without @entity204 or definite stent @entity715 . TLR and @entity583 rates were 6.8% (n=5) and 2.7% (n=2), respectively. CONCLUSIONS: The use of the BiOSS @entity18282 dedicated bifurcation stent for the treatment of @entity850 was feasible and safe, with promising long-term clinical effectiveness.

Long-term effectiveness and safety of the XXXX -eluting BiOSS @entity18282   dedicated bifurcation stent in the treatment of distal left main stenosis: an international registry.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity18282 :: ('10611', 'Gene') :: ['LIM'] @entity75 :: ('MESH:D001927', 'Disease') :: ['target lesion'] @entity3446 :: ('MESH:D020123', 'Chemical') :: ['sirolimus'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity850 :: ('MESH:D003251', 'Disease') :: ['distal LM stenosis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['cardiac death'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity3446 :: (MESH:D020123,Chemical) :: ['sirolimus']
