OBJECTIVE: Epidural corticosteroid injections have been used extensively to treat @entity615 , but the relative effectiveness of one corticosteroid versus another has never been reported in a large @entity1 series. We retrospectively reviewed 597 @entity1 who had epidural corticosteroid injections to determine any difference in Kenalog or @entity5935 efficacy. MATERIALS AND METHODS: We reviewed charts and self-reported @entity158 score evaluations of 597 @entity1 who received either Kenalog or @entity5935 Soluspan as an epidural injection for the treatment of @entity615 from 1997 to 2002 at our university hospital and affiliated Veterans Affairs hospital. Kenalog was used for the initial 2 years and @entity5935 was used for the next 3 years. Fluoroscopic guidance was used to confirm epidural location, and each @entity1 was injected with a mixture of 5 mL of 0.5% preservative-free @entity3303 and 2 mL of either Kenalog 40 mg/mL ( @entity2995 injectable suspension) or @entity5935 Soluspan 6 mg/mL ( @entity17788 and @entity43756 injectable suspension). Each @entity1 was given a standardized @entity158 evaluation sheet that used an 11-point scale for initial @entity158 severity. Scoring of @entity158 compared with baseline during the following 14 days was based on a 5-point scale of @entity158 improvement or worsening. RESULTS: On days 0-3 after the procedure, no statistical significance in improvement of lower back and buttock @entity158 was seen between groups. On day 7, 59% of @entity5935 recipients and 73% of Kenalog recipients showed improvement in @entity615 (p = 0.002, Pearson's chi-square test), and 58% of @entity5935 recipients and 75% of Kenalog recipients had improvement in leg or buttock @entity158 (p < 0.001). On day 14, 54% of @entity5935 recipients and 71% of Kenalog recipients showed improvement in @entity615 (p < 0.001), and 54% of @entity5935 recipients and 71% of Kenalog recipients had improvement in leg or buttock @entity158 (p < 0.001). CONCLUSION: The epidural injection of @entity5935 Soluspan and Kenalog reduced lower back and @entity158 in more than half the @entity1 , although Kenalog reduced @entity158 in a significantly larger number of @entity1 than @entity5935 Soluspan at 1 and 2 weeks after injection.

Efficacy of epidural injections of Kenalog and XXXX in the treatment of @entity615 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2995 :: ('MESH:D014222', 'Chemical') :: ['triamcinolone acetonide'] @entity17788 :: ('MESH:C028994', 'Chemical') :: ['betamethasone sodium phosphate'] @entity5935 :: ('MESH:D001623', 'Chemical') :: ['Celestone'] @entity615 :: ('MESH:D001416', 'Disease') :: ['lower back pain'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity43756 :: ('CHEBI:31275', 'Chemical') :: ['betamethasone acetate'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'radicular pain']
@entity5935 :: (MESH:D001623,Chemical) :: ['Celestone']
