OBJECTIVE: Hemodynamics of a pregnant @entity1 differ and change over time depending on the age of gestation. In the general population, @entity551 ( @entity13519 -AoSP) difference is known and discussed, whereas in pregnancy, it is not established. On the basis of theoretical premises it is probably different and changes with time of gestation. As AoSP is more relevant for internal organs, also for placental perfusion, and still not widely available in clinical practice, knowledge of the average @entity13519 -AoSP difference in a healthy and complicated pregnancy could be of additional value for the management of pregnancy @entity101 . The aim of this study was to assess the @entity13519 -AoSP difference in healthy and @entity101 pregnancies in comparison with nonpregnant controls. @entity1 AND METHODS: Aortic blood pressure with applanation tonometry and brachial blood pressure under standardized conditions were measured monthly and once postpartum in 36 normotensive pregnant @entity1 (age: 29.6  4.8 years) and compared with 25 @entity101 pregnancies (age: 30.5  5.4 years) before antihypertensive treatment implementation and with 25 nonpregnant controls (age: 30.2  5.5 years). RESULTS: In @entity101 pregnancies, the @entity13519 -AoSP difference was smaller throughout the entire pregnancy than in healthy pregnancies (in the second and third trimester: 14.44 vs. 15.7   mmHg, P=0.002, and 12.9 vs. 14   mmHg, P=0.02), and smaller than that in nonpregnant controls (14.88   mmHg, for third trimester, P=0.036). Comparison of healthy pregnancy and controls showed an insignificant increase in @entity13519 -AoSP difference in the first and second trimester, whereas in the third trimester, because of a larger increase of AoSP, the @entity13519 -AoSP difference was smaller than that in nonpregnant controls (14.66   mmHg, P>0.05). CONCLUSION: A reduced @entity13519 -AoSP difference was found in @entity101 pregnancies compared with healthy controls, which may signify a narrower safety margin for complications. Comparison of pregnant @entity1 with nonpregnant controls showed that a significant difference for the @entity13519 -AoSP difference was present only for the postpartum period.

Difference between central and peripheral blood pressure in healthy and XXXX -complicated pregnancy.

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'PARTICIPANTS'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'hypertensive'] @entity551 :: ('MESH:D007022', 'Disease') :: ['brachial-aortic systolic pressure'] @entity13519 :: ('8991', 'Gene') :: ['SBP']
@entity101 :: (MESH:D006973,Disease) :: ['hypertension']
