BACKGROUND: Most previously published studies of @entity1 with @entity3630 are small or have short follow-up period. We report the outcome of a fairly large cohort of @entity1 followed up for nearly 10 years. METHODS: Retrospective cohort study. Graft survival, recurrence rate and risk factors for recurrence were analyzed for 43 @entity1 transplanted between the years 1995 and 2012. RESULTS: At a mean overall follow-up of 118    61 months (median, 127.8; range, 4.9-217), 12 @entity1 lost their graft (28%). Death-censored actuarial 15-year graft survival rate was 56%. @entity631 recurred in eight @entity1 (19%) at a median time of 15.4 months (range, 4.4-70 months). Recurrence led to graft loss in seven @entity1 (88%) within a median of 11.6 months (range, 1.3-54 months) from diagnosis. Median graft survival was 30.5 months for recurrence (range, 7-86). Actuarial 15-year graft survival was 71% for nonrecurrent. The risk for recurrence was higher for @entity1 with human @entity4107 (odds ratio, 16.9; 95% confidence interval, 1.1-246; P=0.038) and HLA @entity4107 (odds ratio, 15.9; 95% confidence interval, 1.07-237; P=0.044) alleles. A trend toward increased risk was found with shorter duration of dialysis before transplantation. Four of 16 (25%) living-related versus none of the living-unrelated donors' recipients recurred. The HLA B49, @entity4295 after transplantation, previous transplantations, and Arab origin were all associated with decreased graft and @entity1 survival. CONCLUSION: @entity1 without recurrence in the first years should expect an excellent graft survival. Nonrelated living donors should be preferred. The HLA B49 and @entity4107 alleles may increase the risk for recurrence.

Recurrent XXXX after kidney transplantation: a 17-year single-center experience.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity4295 :: ('MESH:D007683', 'Disease') :: ['acute tubular necrosis'] @entity3630 :: ('MESH:D015432', 'Disease') :: ['membranoproliferative glomerulonephritis type I'] @entity631 :: ('MESH:D005921', 'Disease') :: ['Membranoproliferative glomerulonephritis'] @entity4107 :: ('3126', 'Gene') :: ['DR4', 'leukocyte antigen (HLA) B49']
@entity3630 :: (MESH:D015432,Disease) :: ['membranoproliferative glomerulonephritis type I']
