PURPOSE: Corrective strabismus surgery is associated with moderate @entity158 after surgery. Postoperative analgesia for these @entity1 may include topical local anesthetic agents and topical non-steroidal anti-inflammatory drugs. In this prospective randomized, double-blind placebo controlled clinical trial we compared the effect of placebo to intraoperative 0.5% topical @entity6513 or 0.5% topical @entity6058 on @entity158 control after strabismus surgery in @entity1 . METHODS: Following Institutional Ethics Committee approval and parental consent, we prospectively studied 51 healthy @entity1 between the ages of two and seven years who were undergoing elective bilateral recession surgery in a randomized, double-blind controlled clinical trial. @entity1 were randomized to receive either placebo (normal saline), 0.5% @entity6513 or 0.5% @entity6058 eye drops at the start and end of strabismus repair surgery. @entity158 was assessed with a modified @entity1 's Hospital of Eastern Ontario @entity158 Score in the recovery room. If the @entity158 score was greater than 6, the @entity1 was administered a single oral dose of @entity1443 (20 mg x kg(-1)). RESULTS: The groups had similar demographic data. Duration of surgery and anesthesia, time spent in recovery room and length of hospital stay between the three groups were similar. @entity158 scores and analgesic requirements while in the hospital were also similar between the groups as was the time to first analgesic administration. There were no side effects observed in any of the three treatment arms. CONCLUSION: We conclude that there is no improvement in @entity282 control after the intraoperative administration of topical 0.5% @entity6058 or 0.5% @entity6513 when compared to placebo in @entity1 undergoing strabismus surgery.

XXXX or @entity6058 eyedrops provide inadequate analgesia in pediatric strabismus surgery.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'Children', 'patient'] @entity6058 :: ('MESH:D020910', 'Chemical') :: ['ketorolac'] @entity6513 :: ('MESH:D013748', 'Chemical') :: ['amethocaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['acetaminophen'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain']
@entity6513 :: (MESH:D013748,Chemical) :: ['Amethocaine']
