BACKGROUND: The reactive form of @entity5145 appears inducible by exposure to agents of infectious @entity294 , but do those organisms represent the tip of the iceberg, as indicated by renewed @entity344 ? Prevalence of @entity5145 (20% of @entity831 [Pan] and 28% of @entity17056 ) is independent of subspecies and species, respectively. However, there are major differences in @entity625 patterns, a characteristic shared with @entity1 . OBJECTIVES: Do patterns of @entity625 correlate with @entity344 ? Could such associated modifications be in the form of disease induction or represent protective effectors (at least against the extent of @entity625 )? METHODS: The skeletons of 2 @entity831 (79 @entity831 troglodytes and 26 @entity831 schweinfurthii) and 2 @entity17056 species (99 @entity17056 and 38 @entity17056 beringei) adults were examined, and @entity625 pattern noted. Feces of Eastern (P. schweinfurthii and G. beringei) and Western (great apes collected in their normal ranges) apes were assessed for 16S rRNA c and its character. RESULTS: Patterns of @entity625 recognized on examination of skeletons showed geographic variation in skeletal distribution. East African apes ( @entity831 schweinfurthii and G. beringei) had pauciarticular @entity625 and frequent @entity66 , whereas West African apes ( @entity831 troglodytes and @entity17056 ) had @entity1897 with minimal sacroiliac involvement. DNA evidence revealed that Corynebactericeae were prominently represented in great apes with @entity66 , whereas Dietzia and Bifidobacterium exposure correlated with reduced @entity625 distribution. CONCLUSIONS: Suggestions of a protective effect (in this case, limiting extent of @entity625 , but not the disease itself) offered by these organisms are well represented by documented effects in other diseases (eg, @entity378 ) in the zoologic record. Perhaps it is this disease-modifying character that reduces the extent of the @entity1897 , while increasing propensity to axial (sacroiliac) disease. A potential role for probiotic organisms in management of @entity625 in @entity1 is suggested, as has been documented for @entity378 , @entity344 , and @entity5419 .

Intestinal Flora Modification of Arthritis Pattern in XXXX .

@entity1 :: ('9606', 'Species') :: ['humans'] @entity17056 :: ('9593', 'Species') :: ['Gorilla gorilla', 'gorilla', 'Gorilla', 'G. gorilla', 'gorillas'] @entity625 :: ('MESH:D001168', 'Disease') :: ['peripheral arthritis', 'arthritis', 'peripheral joint arthritis'] @entity66 :: ('MESH:D004194', 'Disease') :: ['polyarticular disease', 'sacroiliac disease'] @entity5419 :: ('MESH:D005512', 'Disease') :: ['food allergies'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity344 :: ('MESH:D005767', 'Disease') :: ['interest in gastrointestinal flora', 'gastrointestinal disorders', 'gastrointestinal flora'] @entity831 :: ('9598', 'Species') :: ['chimpanzee subspecies', 'P. troglodytes', 'chimpanzees', 'Pan troglodytes'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['polyarticular peripheral joint disease', 'peripheral erosive disease'] @entity5145 :: ('MESH:D025242', 'Disease') :: ['spondyloarthropathy'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculosis']
@entity5145 :: (MESH:D025242,Disease) :: ['Spondyloarthropathy']
