This investigation evaluated bone density in 36 premenopausal @entity1 (mean +/- SD age = 29.5 +/- 8.4 years) an average of 11.4 years after diagnosis for @entity1278 . Twenty-nine @entity1 were aged 20-45 years, and seven were aged 16-19 years. Body composition, age of menarche, length of @entity2588 , @entity172 exposure, and lumbar spine and proximal femur bone density were determined. Average appendicular bone density for those > or = 20 years was found to meet World Health Organization T score criteria for @entity2331 : total femur T = -1.22 and femoral neck T = -1.33. The average total lumbar Z score for all 36 @entity1 was -0.95, which was 90% of the mean for their age, and the mean Z scores for adolescent subjects were within 91% of the mean for their age (Z = -0.84). Years of @entity172 exposure were correlated with lumbar mineral content (r = 0.50, p = 0.002). A modest but significant inverse relationship was observed between length of @entity2588 and femoral and lumbar bone density. The total proximal femur and trochanteric bone densities were best predicted, using stepwise regression, by the number of years after diagnosis and years of @entity2588 , respectively (R2 = 0.23, p = 0.02 and R2 = 0.21, p = 0.04). Lumbar density was best predicted by years of @entity2588 and current percent of ideal body weight (%IBW)(R2 = 0.25, p = 0.02). Length of @entity2588 , @entity172 exposure, and %IBW independently contribute to axial and appendicular bone density. Because of risk for compromised bone density, @entity1 with a history of @entity1278 should be followed longitudinally to maximize premenopausal bone replacement.

Compromised bone density 11.4 years after XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women'] @entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity1278 :: ('MESH:D000856', 'Disease') :: ['anorexia nervosa'] @entity2331 :: ('MESH:D001851', 'Disease') :: ['osteopenia'] @entity2588 :: ('MESH:D000568', 'Disease') :: ['amenorrhea']
@entity1278 :: (MESH:D000856,Disease) :: ['diagnosis of anorexia nervosa']
