PURPOSE: This study aims to investigate any associations of the proinflammatory cytokine @entity1192 in treated @entity1 with @entity29 ( @entity29 ) and the @entity24099 ( @entity24099 ). METHODS: Thirty-four @entity1 with @entity30 ( @entity30 ), 26 with @entity31 ( @entity31 ) and 14 @entity1 with @entity3231 participated in the study. Valid clinical indexes, CRP values and the endoscopic and histologic examination were used for the determination of disease activity. @entity1192 , @entity1356 , @entity1193 ( @entity1193 ) were measured by ELISA. Nonparametric tests were used for continuous and categorical data. RESULTS: Enteropathic @entity3231 diagnosed in 29.4  % @entity30 and 30.8  % @entity31 @entity1 . Active disease had 58.8  % @entity30 (aCD), 76.9  % @entity31 and 50  % @entity3231 @entity1 . Active and inactive @entity30 (iCD) significantly differ on @entity1192 levels (11.2 vs. 3.9  pg/ml; p  =  0.034). Active and inactive @entity31 significantly differ on @entity1356 (3.7 vs. 2.3  pg/ml; p  =  0.054) and @entity1193 levels (15.9 vs. 12.7  pg/ml; p  =  0.023). Active and inactive @entity3231 (iSpA) significantly differ on @entity1193 (16.9 vs. 14.8  pg/ml; p  =  0.033) and marginally on @entity1192 levels (20 vs. 3.9  pg/ml; p  =  0.06). @entity1 with aCD/ieSpA exhibited significant differences on @entity1192 (p  =  0.022) compared to those with iCD/ieSpA. CONCLUSIONS: @entity1192 is associated with @entity30 activity, while @entity1356 and @entity1193 are associated with @entity31 activity in treated @entity1 with @entity29 . Prominent cytokine in SpAs seems to be @entity1192 .

@entity1192 associations in XXXX and the @entity24099 .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity3231 :: ('653509', 'Gene') :: ['SpA'] @entity1356 :: ('3553', 'Gene') :: ['IL-1b'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity1193 :: ('3557', 'Gene') :: ['IL-1 receptor antagonist', 'IL-1Ra'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease', 'IBD'] @entity24099 :: ('MESH:D025241', 'Disease') :: ['enteropathic seronegative spondylarthritis', 'eSpA'] @entity1192 :: ('3552', 'Gene') :: ['IL-1', 'IL-1a'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', "Crohn's disease"]
@entity29 :: (MESH:D015212,Disease) :: ['inflammatory bowel disease']
