OBJECTIVES: To assess the prognosis of pediatric @entity236 transplant recipients requiring mechanical ventilation and to identify risk factors for mortality. DESIGN: Retrospective chart review. SETTING: Pediatric intensive care unit (PICU), tertiary care center. @entity1 : Inclusion criteria were endotracheal intubation and mechanical ventilation after @entity236 transplantation; @entity1 with perioperative ventilation were excluded. Outcome measures were extubation, PICU discharge, and 6-month survival. The 39 @entity1 who met the inclusion criteria were ventilated on 41 occasions. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Overall survival rate to PICU discharge was 44% (17 of 39 @entity1 ). Six months after PICU discharge, 14 of these @entity1 were still alive, for a medium-term survival rate of 36%. Preexisting conditions ( @entity66 , @entity236 engraftment, or graft-vs.-host disease) had no significant effect on survival. @entity881 , especially @entity358 and @entity16 , were significant determinants of @entity1 survival. CONCLUSIONS: The observed prognosis is improved over previous reports. Early initiation of @entity146 intensive care treatment is warranted in this @entity1 group. Decisions regarding intensity of treatment must be based on aspects of the acute illness rather than on the primary conditions.

Prognosis of pediatric XXXX transplant recipients requiring mechanical ventilation.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient', 'PATIENTS'] @entity66 :: ('MESH:D004194', 'Disease') :: ['primary disease'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic deterioration'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary failure'] @entity881 :: ('MESH:D009102', 'Disease') :: ['Multiple organ failure'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow']
@entity236 :: (MESH:D001855,Disease) :: ['bone marrow']
