INTRODUCTION: Extra @entity39 (EPN) alone represents a subgroup of @entity788 with better outcome than @entity1 with @entity39 ( @entity39 ). However, data on clinical significance of @entity68234 is limited and significance of extent of EPN is not known. METHODS: 213 @entity1 (136 (63.8%) males; mean age: 39.8    13.2 years) with @entity656 ( @entity656 ) were prospectively enrolled and followed up till recovery or death. Contrast enhanced computed tomography (CECT) of each @entity1 was retrospectively evaluated for presence of @entity39 and EPN, @entity1143 and @entity843 . EPN was termed extensive if it extended to paracolic gutters or pelvis. RESULTS: 21 (9.9%) @entity1 had @entity788 , 7 (3.3%) @entity1 had @entity39 alone, 48 (22.5%) @entity1 had EPN alone and 137 (64.3%) @entity1 had combined @entity39 _ EPN. @entity1 with EPN alone had significantly higher frequency of organ failure than @entity1 with @entity788 . Compared with @entity1 with EPN alone, the @entity1 with combined @entity39 had significantly higher frequency of @entity1143 (88.2% versus 75%), @entity843 (41% versus 20.8%), and need for intervention (32.6% versus 14.6%). @entity1 with extensive EPN (n=57) had significantly higher frequency of @entity1143 , @entity843 and @entity881 ( @entity881 ) than those with limited EPN. CONCLUSION: EPN alone should be considered as a separate category of @entity656 as it has less severe course than @entity39 but has more severe course than @entity788 . @entity1 with extensive EPN in spite of having increased frequency of @entity843 , @entity1143 and @entity881 had similar outcome as compared to @entity1 with limited EPN.

Clinical Significance of Presence and Extent of Extra @entity39 in Acute XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patients'] @entity1143 :: ('MESH:D010996', 'Disease') :: ['pleural effusion'] @entity788 :: ('MESH:D010190', 'Disease') :: ['interstitial pancreatitis', 'pancreatitis'] @entity656 :: ('MESH:D019283', 'Disease') :: ['AP', 'acute pancreatitis'] @entity39 :: ('MESH:D009336', 'Disease') :: ['PN', 'pancreatic necrosis', 'necrosis', 'pancreatic parenchymal necrosis'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity68234 :: ('CHEBI:34733', 'Chemical') :: ['EPN'] @entity881 :: ('MESH:D009102', 'Disease') :: ['multi-organ failure', 'MOF']
@entity788 :: (MESH:D010190,Disease) :: ['Pancreatitis']
