Endometriosis is a common disease in @entity1 at reproductive age. We investigated the concentration of neutrophil-activating factor (growth-regulated gene-alpha; @entity2851 ) (a member of the chemokine family), in peritoneal fluid of infertile @entity1 with or without @entity46 . Peritoneal fluid was obtained laparoscopically from 22 @entity1 with and 21 without visible @entity75 . @entity2851 concentration was measured by the use of an ELISA kit. Median concentration of @entity2851 was 87.65 +/- 56.19 pg/ml in the study group and 60.72 +/- 11.98 pg/ml in the control group. The distribution of data differed from normal, therefore logarithmic transformation of data was performed. Concentration of @entity2851 was significantly higher in the peritoneal fluid of @entity1 with @entity46 when compared with controls (p = 0.05). No correlation between concentration of @entity2851 , stage of @entity46 , duration of @entity249 or sex @entity134 hormone levels was found. The study shows that @entity2851 may play a role in the pathogenesis of @entity46 , possibly by chemoattraction and activation of neutrophils present in higher numbers in the peritoneal fluid of @entity1 with @entity46 . It is also feasible that the angiogenic properties of @entity2851 might prompt the progression of @entity75 .

Chemokine growth-regulated-alpha: a possible role in the pathogenesis of XXXX .

@entity1 :: ('9606', 'Species') :: ['women'] @entity249 :: ('MESH:D007246', 'Disease') :: ['infertility'] @entity75 :: ('MESH:D001927', 'Disease') :: ['endometriotic lesions'] @entity2851 :: ('2919', 'Gene') :: ['GRO-alpha'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['steroid'] @entity46 :: ('MESH:D004715', 'Disease') :: ['endometriosis']
@entity46 :: (MESH:D004715,Disease) :: ['endometriosis']
