OBJECTIVE: Immigrants in Western countries tend to have a greater risk for @entity65 ( @entity65 ) than those in their home country, but it is unclear if immigrants are at increased risk for @entity65 compared to non-immigrants in their new country. The purpose of this study was to determine the independent association of time since immigration with sub-clinical @entity731 in immigrants of Chinese, European and South Asian origin. METHODS: A total of 460 immigrants and 158 non-immigrants of Chinese, European and South Asian origin without pre-diagnosed @entity65 were assessed for sub-clinical @entity731 by carotid artery ultrasound scan, socio-demographics, @entity65 risk factors and lifestyle factors. Time since immigration in years was used as a measure of exposure. RESULTS: @entity1 who immigrated > or =30 years ago had a greater @entity121 ( @entity121 ) of the carotid artery compared to non-immigrants, and immigrants of < or =20 years. Time since immigration was associated with @entity121 , plaque area and @entity121 +plaque area. After adjustment for age, sex, ethnicity, income, education, family history of @entity65 and @entity6 , smoking, physical activity, body mass index, visceral adipose tissue, lipids, @entity2690 , @entity413 and blood pressure, time since immigration was significantly associated with @entity121 . For every ten years since immigration there was a 2% increase in @entity121 in addition to the 7% increase for every 10 years of age. CONCLUSIONS: Immigration was associated with an increased burden of sub-clinical @entity731 that surpassed that of non-immigrants. This burden increased over time independent of other risk factors. Immigrants represent a high-risk group for which targeted interventions are needed.

Immigration presents a potential increased risk for XXXX .

@entity1 :: ('9606', 'Species') :: ['Participants'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity2690 :: ('3630', 'Gene') :: ['insulin'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity121 :: ('MESH:D009135', 'Disease') :: ['IMT', 'intima-media thickness'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease']
@entity731 :: (MESH:D050197,Disease) :: ['atherosclerosis']
