BACKGROUND: Uncontrolled @entity120 may cause worse outcomes after transcatheter aortic valve replacement (TAVR), while hemodynamic monitoring is desirable for risk control. Pulmonary artery pressure (PAP) readings obtained by intracardiac Doppler echocardiography were evaluated. METHODS: In 114 @entity1 with @entity472 and median Society of Thoracic Surgeons scores of 10.5% (interquartile range, 7.7%-15.0%), transfemoral and transapical TAVR was guided by intracardiac Doppler echocardiography. The continuous-wave Doppler beam interrogated the jet of @entity997 from the "home view" position. Systolic PAP (PAPs) was estimated as the sum of the pressure gradient derived from the maximum transtricuspid regurgitation jet velocity and the central venous pressure. Mean PAP (PAPm) was calculated by the mean gradient method (1) and the Chemla formula (2). Measurements were obtained immediately before and after TAVR. RESULTS: Pre- and postinterventional readings showed marginal pressure underestimation in comparison with measurements derived from right-heart catheterization: PAPs, -2.7 (95% CI, -3.3 to 2.1) and -1.4 (95% CI, -1.9 to -0.9); PAPm by the mean gradient method, -1.9 (95% CI, -2.2 to -1.6) and -0.1 (95% CI, -0.4 to 0.2). Agreement (95% limits) for PAPs was -8.6 to 3.2 and -6.8 to 4.0; agreement for PAPm by the mean gradient method was -5.4 to 1.6 and -3.4 to 3.2. The repeatability coefficient (95% limits of agreement) for PAPs was excellent: 3.4 (-4.2 to 2.5) and 5.5 (-5.3 to 5.8); repeatability for PAPm was higher by the mean gradient method than by the Chemla method. In >= 85% of @entity1 with @entity120 , PAPm improved after valve deployment. CONCLUSIONS: Intracardiac Doppler echocardiography-derived monitoring of PAP by the mean gradient method is accurate and well applicable to high-risk TAVR candidates for intraprocedural risk control.

Intracardiac Doppler Echocardiography for  Monitoring of Pulmonary Artery Pressures in  High-Risk XXXX Undergoing Transcatheter Aortic Valve Replacement.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity472 :: ('MESH:D001024', 'Disease') :: ['symptomatic aortic stenosis'] @entity997 :: ('MESH:D014262', 'Disease') :: ['tricuspid regurgitation'] @entity120 :: ('MESH:D006976', 'Disease') :: ['pulmonary hypertension']
@entity1 :: (9606,Species) :: ['Patients']
