Two experiments were conducted to evaluate the effects of early feed restriction on lipid peroxidation, @entity6980 and @entity843 incidence in broilers under normal and low ambient temperature. In experiment 1, the restricted birds were fed 8h per day either from 7 to 14 d or from 7 to 21 d, while the controlled birds were fed ad libitum. In experiment 2, the restricted birds were fed 80 or 60% of the previous 24-h feed consumption of full-fed controls for 7 d from 7 to 14 d. On d 14, half of the birds in each treatment both in experiment 1 and experiment 2 were exposed to low ambient temperature to induce @entity843 . Body weight and feed conversion ratio were measured weekly. The incidences of @entity843 and other disease were recorded to determine @entity843 morbidity and total mortality. Blood samples were taken on d 14, 21, 28, 35 and 42 to measure the plasma @entity1234 ( @entity1865 ), @entity224 dismutase (SOD) and @entity2041 peroxidase ( @entity2197 -Px). On d 42, samples were taken to determine the right/total ventricular weight ratio (RV/TV), vessel wall area/vessel total area ratio (WA/TA) and mean media thickness in pulmonary arterioles (mMTPA). Low-temperature treatment increased plasma @entity1865 concentration. When broilers were exposed to a cool environment for 3 weeks, plasma SOD and @entity2197 -Px activity were decreased compared with normal-temperature chicks. RV/TV, WA/TA and mMTPA on d 42 were increased in birds exposed to cold, consistent with the @entity120 and @entity843 morbidity. Early feed restriction markedly decreased plasma @entity1865 concentration. The plasma SOD and @entity2197 -Px activity of feed-restricted birds were markedly higher than those fed ad libitum on d 35 and d 42. All early feed restriction treatments reduced @entity843 morbidity and total mortality. On d 42, the RV/TV, WA/TA and mMTPA of feed-restricted broilers were lower than that of the ad libitum-fed broilers. The results suggested that early feed restriction alleviated the lipid peroxidation, promoted the activity of enzymatic antioxidant and inhibited @entity6980 . These changes might be associated with reduced @entity843 incidence.

Effects of early feed restriction and cold temperature on lipid peroxidation, XXXX in broilers under normal and cold temperature.

@entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity2041 :: ('MESH:D005978', 'Chemical') :: ['glutathione'] @entity120 :: ('MESH:D006976', 'Disease') :: ['increased pulmonary hypertension'] @entity6980 :: ('MESH:D066253', 'Disease') :: ['pulmonary vascular remodelling'] @entity2197 :: ('CHEBI:16856', 'Chemical') :: ['GSH'] @entity1234 :: ('MESH:D008315', 'Chemical') :: ['malondialdehyde'] @entity224 :: ('MESH:D013481', 'Chemical') :: ['superoxide'] @entity1865 :: ('CHEBI:566274', 'Chemical') :: ['MDA']
@entity6980 :: (MESH:D066253,Disease) :: ['pulmonary vascular remodelling and ascites morbidity']
