OBJECTIVE: In a 5-year followup study, we investigated the temporal relationship between development of @entity2720 as visualized by magnetic resonance imaging (MRI) versus conventional radiography (CR), in @entity1 with @entity309 . We also evaluated the risk of erosive progression on CR associated with the presence of @entity2996 . METHODS: In 10 @entity1 with @entity309 , MRI and CR of the dominant wrist were performed annually for 5 years. In each image set, each wrist bone (metacarpal bases, carpal bones, radius, and ulna) was assessed for the absence or presence of @entity79 . RESULTS: Nine bones showed radiographic erosions at baseline. Twenty-seven new radiographic erosions developed during the 5-year followup period. Of these 27 new erosions, 21 were detected 1-5 years earlier by MRI than by CR, 3 were simultaneously detected by both methods, 2 were detected 1-2 years later by MRI than by CR, and 1 @entity2681 (radiographically detected at 5-year followup) was not visualized with MRI. MRI detection of new radiographic erosions preceded CR detection by a median of 2 years. In bones with @entity2996 at baseline, the relative risk of radiographic erosions at 5-year followup was 4.5 (95% confidence interval [95% CI] 2.6-7.6), compared with bones without baseline @entity2996 . If bones with baseline radiographic erosions were excluded from the analysis, the relative risk was 4.1 (95% CI 2.2-7.5). CONCLUSION: Most new radiographic @entity79 (78%) were visualized at least 1 year earlier by MRI than by CR. This illustrates that the information on joint destruction provided by CR is considerably delayed compared with that provided by MRI. A significantly increased risk of progression of @entity79 was observed, demonstrating a prognostic value of MRI with respect to long-term radiographic outcome.

New radiographic @entity79 in the wrists of @entity1 with XXXX are detectable with magnetic resonance imaging a median of two years earlier.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2681 :: ('MESH:D014077', 'Disease') :: ['erosion'] @entity2996 :: ('MESH:C564543', 'Disease') :: ['MRI erosions'] @entity79 :: ('MESH:D001847', 'Disease') :: ['radiographic erosion in bones with baseline MRI erosions', 'bone erosions'] @entity2720 :: ('MESH:D007592', 'Disease') :: ['wrist joint erosions'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis']
@entity309 :: (MESH:D001172,Disease) :: ['rheumatoid arthritis']
