UNASSIGNED: Objective: To evaluate the choice of surgical treatment of @entity3821 ( @entity3821 ) and its impact on long-term outcomes. Methods: A retrospective analysis of the clinicopathological features and treatment protocol of @entity3821 @entity1 who underwent surgical treatment in Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiaotong University School of Medicine from January 2009 to August 2016 was done. The factors which could affect surgical treatment were analyzed by   (2) test and Logistic regression. Survival analysis were performed between different surgical approaches. Kaplan-Meier survival curves and Log-rank tests demonstrated the distribution of disease free survival and overall survival. Results: A total of 526 @entity1 were enrolled in this study, 405 cases (77.0%) underwent mastectomy, 121 cases (23.0%) underwent breast-conserving surgery, of which 88 cases received radiotherapy after breast-conserving surgery. It was shown by univariate and multivariate analysis that age>50 years (OR=0.631, 95% CI: 0.413 to 0.965, P=0.034), first symptom of nipple discharge (OR=0.316, 95% CI: 0.120 to 0.834, P=0.020), excision biopsy (OR=1.831, 95% CI: 1.182 to 2.835, P=0.007) and @entity5 size >3 cm (OR=0.422, 95% CI: 0.206 to 0.864, P=0.018) were significantly correlated with choice of surgical treatment for @entity1558 . Axillary lymph node dissection was performed for 118 cases (22.4%), with sentinel lymph node biopsy for 327 cases (62.2%), and none for 81 cases (15.4%). There was significant statistical difference in the choice of axillary lymph node management in @entity1 of different age (  (2)=8.124, P=0.017), biopsy type (  (2)=35.567, P=0.000), breast operation type (  (2)=149.118, P=0.000) and @entity5 size (  (2)=13.394, P=0.010). The 5-year disease free survival rates was 95.7%, 89.6% and 100%, respectively, for mastectomy group, breast-conserving surgery group and breast-conserving surgery plus radiotherapy group. And the 5-year overall survival rates for three groups were 99.0%, 100% and 100%. The differences were not statistically significant (P=0.427, 0.777). Conclusions: For @entity3821 @entity1 , age, first symptom and @entity5 size are independent predictors of breast surgery. The choice of axillary lymph node surgery is influenced by age, biopsy, operation type, and @entity5 size. Different surgical treatment options has no significant effect on disease-free survival and overall survival in @entity3821 @entity1 .

[Surgical treatment and prognosis of XXXX : 526 cases analysis].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1558 :: ('MESH:D001941', 'Disease') :: ['breast lesions'] @entity3821 :: ('MESH:D002285', 'Disease') :: ['ductal carcinoma in situ', 'DCIS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor']
@entity3821 :: (MESH:D002285,Disease) :: ['ductal carcinoma in situ']
