@entity292 is the most common complication (8.7 to 22%) in the immediate postoperative period following total laryngectomy. The study's objective was to determine the incidence of post-laryngectomy @entity292 in @entity1 operated on in our department to establish whether specific factors predispose to @entity292 formation and to determine whether @entity292 and @entity5 recurrence are related. Between 1992 and 2001, 377 cases of @entity189 were diagnosed, and the @entity1 underwent total laryngectomy in our department. Of these @entity1 , 291 had total laryngectomy as the primary management of their disease, while in 86 @entity1 the operation treated recurrence of the disease. In 92 @entity1 , total laryngectomy was combined with radical or eclectic neck dissection. The presence of @entity86 was established in 49 of the 377 @entity1 (13%) studied. The cancerous stage, exact localization of the @entity5 , degree of differentiation, previous irradiation, @entity1 's age, performance or not of neck dissection or emergency tracheostomy and fitting of voice prostheses were all factors that, after statistical analysis, did not appear to significantly influence the incidence of @entity86 . Factors that did show statistical significance were the histological infiltration of the @entity5 's surgical margins (11% negative vs. 38% with positive margins) and coexisting early complications. Fistula management was conservative in the majority of cases. The necessary closure period for a @entity292 varied between 5 and 81 days (mean: 29 days). Postoperative follow-up of all @entity1 revealed that @entity292 did not influence the incidence of @entity5 recurrence. The incidence of @entity86 in our study was 13%. @entity5 and coexisting complications were related, among other things, to a higher rate of @entity292 formation. The rate of @entity5 recurrence after total laryngectomy was not related to the presence of a @entity292 during the postoperative period.

Incidence and predisposing factors of pharyngocutaneous @entity292 formation after total laryngectomy. Is there a relationship with XXXX recurrence?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Incomplete excision of the tumor'] @entity189 :: ('MESH:D002277', 'Disease') :: ['laryngeal carcinoma'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula', 'fistulas', 'Pharyngocutaneous fistula'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative fistulas', 'early postoperative fistula']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
