Anatomical studies suggest that sites of @entity3361 are subject to early @entity731 . Coronary angiography is unable to confirm the lesions or provide information about their nature. On the other hand, endocoronary ultrasound is able to identify and, it is hoped, to determine the frequency and composition of the lesions. Nineteen @entity1 with @entity662 and angiographically normal or subnormal coronary arteries were included in a prospective study (16 @entity1 and 3 @entity1 : average age 53 +/- 10 years). Four @entity1 had spontaneous @entity2473 and in the other 15, @entity2473 was induced by intravenous injection of @entity3693 (6 micrograms/kg). After countering the @entity2473 with @entity3763 , the site of @entity2473 and adjacent segments were examined by endocoronary ultrasound. Localised @entity2553 which was stenotic in 14 cases and obstructive in 5 cases, was observed. The ECG was unchanged in 4 cases and showed ST-T segment changes in 15 cases. The artery affected was the left anterior descending in 10 cases, the left circumflex in 2 cases and the right coronary in 7 cases. A plaque of @entity1856 , defined as significant intimal thickening, was detected in 18 out of the 19 cases. This @entity1856 was classified as soft in 17 cases and hard in one case. The authors conclude that @entity2553 is not only associated with a plaque of @entity1856 , nearly always suspected at coronary angiography, but also its composition is nearly always soft (lipidic) from ultrasonographic data.

[Frequency and nature of XXXX at the site of @entity2473 of angiographically normal or subnormal coronary arteries: an endocoronary ultrasonographic study].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity3763 :: ('MESH:D007548', 'Chemical') :: ['isosorbide dinitrate'] @entity3361 :: ('MESH:D003329', 'Disease') :: ['coronary spasm'] @entity2553 :: ('MESH:D020301', 'Disease') :: ['vasospasm'] @entity2473 :: ('MESH:D013035', 'Disease') :: ['spasm'] @entity1856 :: ('MESH:D058226', 'Disease') :: ['atheroma'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity3693 :: ('MESH:D004874', 'Chemical') :: ['ergometrine']
@entity1856 :: (MESH:D058226,Disease) :: ['atheroma']
