BACKGROUND: The use of @entity1169 has been proposed to reduce the @entity2495 response of @entity1 with @entity130 . OBJECTIVES: To review the studies published up to December 2013 on the effects of @entity1169 in burn @entity1 . METHODS: A PubMed search was conducted using the terms   burns  ,   @entity130  ,   beta-blocker   and   @entity1169  , with the filters   @entity1   and   English   and   Spanish  . A total of 42 citations were retrieved, 15 of which were randomized clinical trials. The main results are summarized. MAIN RESULTS: @entity1169 at doses adjusted to decrease the heart rate by 20% of the baseline value (4-6mg/kg/day p.o.) reduces supraphysiological thermogenesis, cardiac work, resting energy expenditure and peripheral lipolysis. It likewise increases the efficiency of muscular protein synthesis and reduces central mass accretion. Most studies have been conducted in pediatric burn @entity1 . CONCLUSIONS: @entity1169 reduces the @entity2495 response in pediatric burn @entity1 . More studies on its effects in adult burn @entity1 are needed.

Systematic review of the effect of @entity1169 on hypermetabilism in XXXX .

@entity1169 :: ('MESH:D011433', 'Chemical') :: ['propranolol', 'Propranolol'] @entity2495 :: ('MESH:C565498', 'Disease') :: ['hypermetabolic'] @entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity130 :: ('MESH:D014947', 'Disease') :: ['burn injuries', 'thermal injury']
@entity130 :: (MESH:D014947,Disease) :: ['burn injuries']
