BACKGROUND: Mycotic @entity449 (MAA) is a rare and life-threatening disease. The aim of this European multicenter collaboration was to study the durability of endovascular aortic repair (EVAR) of @entity11596 , by assessing late @entity281 and long-term survival. METHODS AND RESULTS: All EVAR treated MAAs, between 1999 and 2013 at 16 European centers, were retrospectively reviewed. One hundred twenty-three @entity1 with 130 MAAs were identified. Mean age was 69 years (range 39-86), 87 (71%) were @entity1 , 58 (47%) had @entity465 , and 47 (38%) presented with @entity397 . Anatomic locations were ascending/arch (n=4), descending (n=34), paravisceral (n=15), infrarenal aorta (n=63), and multiple (n=7). Treatments were thoracic EVAR (n=43), fenestrated/branched EVAR (n=9), and infrarenal EVAR (n=71). Antibiotic was administered for mean 30 weeks. Mean follow-up was 35 months (range 1 week to 149 months). Six @entity1 (5%) were converted to open repair during follow-up. Survival was 91% (95% confidence interval, 86% to 96%), 75% (67% to 83%), 55% (44% to 66%), and 41% (28% to 54%) after 1, 12, 60, and 120 months, respectively. Infection-related @entity204 occurred in 23 @entity1 (19%), 9 after discontinuation of antibiotic treatment. A Cox regression analysis demonstrated non-Salmonella-positive culture as predictors for late @entity204 . CONCLUSIONS: Endovascular treatment of MAA is feasible and for most @entity1 a durable treatment option. Late infections do occur, are often lethal, and warrant long-term antibiotic treatment and follow-up. @entity1 with @entity1503 were more likely to die from late infection.

Endovascular Treatment of Mycotic XXXX : A European Multicenter Study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity449 :: ('MESH:D001014', 'Disease') :: ['aortic aneurysm'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['non-Salmonella-positive blood cultures'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection-related complications'] @entity465 :: ('MESH:D007153', 'Disease') :: ['immunodeficiency'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture'] @entity11596 :: ('CHEBI:35738', 'Chemical') :: ['MAA'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'infection-related death']
@entity449 :: (MESH:D001014,Disease) :: ['Aortic Aneurysms']
