OBJECTIVE: To study the safety and effectiveness of laparoscopic radiofrequency ablation for centrally located @entity703 . METHODS: From January 2009 to April 2013, thirteen @entity1 who diagnosed as centrally located @entity703 were treated with laparoscopic radiofrequency ablation in the Department of Urology of Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School. All of the cases were T1aN0M0 stage, 9 @entity1 were male, 4 were female, the mean age was 56 years (range, 38-73 years). All @entity5 were unilateral, eight lesions were in the left kidney and five in the right kidney. Intraoperative real-time ultrasound and temperature probes were used to guide the range of radiofrequency ablation. Ice saline was injected through ureteral catheter for cooling the collecting system. The postoperative serum @entity1011 and glomerular filtration rate (GFR) data were collected,all @entity1 were followed up with enhanced CT or MRI.The pre- and post-operative date were compared by paired t test. RESULTS: All @entity1 underwent laparoscopic radiofrequency ablation successfully. The mean operation time was (113  13) minutes and the mean @entity190 was (99  23) ml. The mean pre- and post-operative serum @entity1011 was (71  11)   mol/L and (74  11)   mol/L, the mean pre- and post-operative GFR was (49  8) ml/min and (45  7) ml/min. There was no significant statistic difference between pre-operation and post-operation (t=-1.371 and 1.986, P>0.05). The mean follow-up was 37 months, range 12-63 months. No evidence of local recurrence or distant @entity3 was found. CONCLUSIONS: Laparoscopic radiofrequency ablation for T1aN0M0 centrally located @entity703 could be performed safely with good outcomes. Intraoperative real-time ultrasound and temperature probes are helpful to control the range of radiofrequency ablation. Physical cooling of renal collecting system could reduce the occurrence of postoperative @entity3041 and leakage of urine.

[Laparoscopic radiofrequency ablation for centrally located XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity3041 :: ('MESH:D006869', 'Disease') :: ['hydronephrosis'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal tumors']
@entity703 :: (MESH:D007680,Disease) :: ['renal tumors']
