BACKGROUND: To compare the correlation of TANIS and 1997 UICC stage grouping with survival rate in @entity135 . METHODS: A series of 820 @entity1 affected by @entity189 of paranasal sinuses (43 @entity1 ), oral cavity (100 @entity1 ), oropharynx (64 @entity1 ), larynx (599 @entity1 ) and parotid gland (134 @entity1 ) was considered in this retrospective study for a minimum follow-up of 5 years. The data set was classified according to 1997 UICC T-category and then grouped as recommended by the two systems. Data were analyzed by means of survival analyses (Kaplan-Meier and Cox algorithms). RESULTS: The total disease-specific survival rate at 5 years was 44% for paranasal sinuses, 54% for oral cavity, 28% for oropharynx, 86% for larynx and 65% for parotid gland. Globally, univariate analysis by means of Log Rank Test yielded significant p-values both for TANIS and 1997 UICC systems. Multivariate analysis (Cox regression adjusted for age and gender) showed a significant correlation between the two staging systems with the mortality rate. However, TANIS resulted in a higher prognostic value in oral cavity, oropharynx and larynx that are three sites affected by a homogeneous histological type of @entity189 (i.e. @entity957 ). CONCLUSIONS: TANIS stage grouping better defines the prognosis for @entity135 than the 1997 UICC system.

[Stage grouping for XXXX : a meta-analysis].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck carcinoma', 'head and neck cancer'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinorna'] @entity189 :: ('MESH:D002277', 'Disease') :: ['primary carcinoma', 'carcinoma']
@entity135 :: (MESH:D006258,Disease) :: ['head and neck cancer']
