The aim of this pilot study was to evaluate the incidence of @entity5886 and its association with clinical outcome in @entity879 ( @entity879 ). @entity1 with @entity879 referred for orthotopic liver transplantation (OLT) between January, 1991 and May, 2002 were identified. @entity879 was defined as the development of @entity1003 and @entity75 within 8 weeks of onset of @entity1087 . Demographic and laboratory data, including serum @entity1391 , @entity460 , @entity1760 , @entity1011 , and PT/INR were obtained from medical records. Clinical outcomes ( @entity204 , OLT, or hepatic recovery) and associated morbidities ( @entity177 , @entity548 , and @entity295 ) also were noted. Thirty-eight @entity1 , 8 @entity1 and 30 @entity1 , aged 34 +/- 4 years, were included in the study. @entity5886 (< 2.5 mg/dL) developed in 33 of 38 (87%) @entity1 within 10 days of referral. Twelve @entity1 (32%) died, 14 @entity1 (37%) underwent OLT, and 12 @entity1 (32%) recovered. The mean nadir serum @entity3151 level was significantly lower in those who recovered compared with those who either died or required OLT (1.18 +/- 0.54 versus 1.79 +/- 1.00 mg/dL; P =.02). A trend toward lower mean serum @entity3151 level also was noted in those who recovered compared with those who died (1.18 +/- 0.54 versus 1.96 +/- 1.35 mg/dL; P =.09). Serum @entity3151 levels > 2.5 mg/dL was a predictor of mortality, and when used alone, was equivalent to the King's College Criteria. In conclusion, @entity5886 occurred frequently in @entity1 with @entity879 . Lower serum @entity3151 levels were observed in @entity1 who recovered as compared with those who died or required OLT, and may be associated with recovery of hepatic function. The greater decline in serum @entity3151 level in those who recover hepatic function may represent cellular use of @entity3151 during hepatocyte regeneration.

Serum XXXX levels predict clinical outcome in @entity879 .

@entity1 :: ('9606', 'Species') :: ['men', 'Patients', 'women', 'patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity75 :: ('MESH:D001927', 'Disease') :: ['encephalopathy'] @entity879 :: ('MESH:D017114', 'Disease') :: ['fulminant hepatic failure', 'FHF'] @entity1003 :: ('MESH:D001778', 'Disease') :: ['coagulopathy'] @entity5886 :: ('MESH:D017674', 'Disease') :: ['Hypophosphatemia', 'hypophosphatemia'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity1391 :: ('CHEBI:26020', 'Chemical') :: ['phosphate'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity3151 :: ('MESH:D010758', 'Chemical') :: ['phosphorus'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity1760 :: ('MESH:D008274', 'Chemical') :: ['magnesium']
@entity3151 :: (MESH:D010758,Chemical) :: ['phosphorus']
