We investigated the feasibility of contrast enhanced (CE)-dynamic magnetic resonance imaging (MRI) for the detection of @entity4115 induced hypoperfusion in an experimental @entity35 model. Adult @entity35 were subjected to unilateral @entity4115 of 360 or 720 degrees. After 1 h, the tail veins of the anaesthetized @entity35 were cannulated and T2 -, diffusion-weighted and T1-weighted CE-dynamic MRI were subsequently performed by a 1.5 T MRI scanner. On apparent diffusion coefficient (ADC) images, the region of interest values of the ischaemic and control testes was compared. From CE-dynamic MR images, the maximal slopes of contrast enhancement were calculated and compared. In @entity4115 of 360 degrees, the maximal slope of contrast enhancement was 0.072%/s vs. 0.47%/s in the contralateral control @entity1062 (p < 0.001). A torsion of 720 degrees diminished the slope of contrast enhancement to 0.046%/s vs. 0.37%/s in the contralateral @entity1062 (p < 0.001). Diminished blood flow during torsion also followed in decreased ADC values in both 360 degrees (12.4% decrease; p < 0.05) and 720 degrees (10.8% decrease; p < 0.001) of torsion. Torsion of the @entity1062 causes @entity717 and decreased @entity2287 uptake in a @entity35 model that can be easily detected and quantified by CE-dynamic MRI. In diffusion-weighted MRI images, acute hypoperfusion results in a slight decrease of ADC values. Our results suggest that CE-dynamic MRI in combination with diffusion-weighted MRI can be used to detect compromised blood flow due to acute @entity4115 .

Magnetic resonance imaging of experimental XXXX .

@entity4115 :: ('MESH:D013086', 'Disease') :: ['testicular torsion'] @entity1062 :: ('MESH:D013736', 'Disease') :: ['testis'] @entity35 :: ('10116', 'Species') :: ['rat', 'Sprague-Dawley rats', 'rats'] @entity717 :: ('MESH:D009069', 'Disease') :: ['ipsilateral hypoperfusion'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium']
@entity4115 :: (MESH:D013086,Disease) :: ['testicular torsion']
