BACKGROUND: Hospitalisation for acute exacerbations of @entity1030 is associated with high risk of readmission. However, no tool has been validated to stratify @entity1 at discharge for risk of readmission. AIM: To evaluate the ability of the 4 m gait speed (4MGS), a surrogate marker of frailty, to predict risk of future readmission in hospitalised @entity1 with an acute exacerbation of @entity1030 (AECOPD). METHODS: 213 @entity1 hospitalised with an AECOPD were recruited prospectively. 4MGS was measured on day of discharge. @entity2357 models were used to assess the association between 4MGS and readmission at 90 days after discharge. RESULTS: Baseline characteristics of the cohort: 52% @entity1 ; mean age 72 years; median FEV1 35%predicted. Mean (SD) 4MGS at hospital discharge was 0.61 (0.26) ms(-1). Significant increased rates of all-cause readmission at 90 days were seen across quartiles of decreasing 4MGS (Q4 fastest: 11.5%; Q3: 20.4%; Q2: 30.2%; Q1 slowest: 48.2%; p trend<0.001). Compared with Q4, those in the slowest 4MGS quartile had unadjusted ORs (95% CIs) for 90-day readmission of 7.12 (2.61 to 19.44) for the whole cohort and 11.56 (3.08 to 43.35) in those aged 65 or over. A multivariate model incorporating 4MGS, Charlson Index, hospital admission in past year, FEV1%predicted and number of exacerbations in past year in those aged 65 or over predicted 90-day readmission with a C-statistic of 0.86. CONCLUSIONS: The 4MGS, a surrogate marker of physical frailty, independently predicts the risk of readmission in older @entity1 hospitalised for acute exacerbation of @entity1030 . TRIAL REGISTRATION NUMBER: NCT01507415.

Gait speed and readmission following hospitalisation for acute exacerbations of XXXX : a prospective study.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity2357 :: ('MESH:C537770', 'Disease') :: ['Logistic regression'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['COPD']
@entity1030 :: (MESH:D029424,Disease) :: ['COPD']
