BACKGROUND: Conflicting data exist regarding whether low @entity79 ( @entity79 ) is associated with @entity11807 ( @entity11807 ). The current study identified the frequency of low @entity79 in @entity11807 , expecting low @entity79 even in childhood and before HCT. PROCEDURE: Thirty-seven @entity11807 @entity1 (18 prior HCT, 19 no prior HCT), participating in an IRB-approved database, had clinical assessment of DXA of lumbar spine @entity79 . Four had used @entity3800 , one later underwent HCT. Most had used glucocorticoids after HCT (prolonged in five), and one more with no HCT. @entity79 [in standard deviation units from mean for age (SD), gender, and ethnicity ( @entity79 Z-score)] was then adjusted for height age, and separately for bone maturation (BA). Data were collected for height SD, pubertal stage, and duration since HCT. RESULTS: @entity79 Z-score (without adjustment) was <-1 SD in half of @entity11807 @entity1 . BA-adjusted @entity79 Z-score was similar. (BA was not usually delayed, although most @entity1 were short.) In contrast, height age-adjusted @entity79 Z-score was normal in most with @entity11807 (only below -2.0 in one @entity1 after prolonged glucocorticoids). Mean duration after HCT until DXA test was 6.2 years (median 4.2 years, range 1-18 years). CONCLUSIONS: @entity1 and adolescents with @entity11807 have normal @entity79 prior to and after HCT, when DXA results are adjusted for bone size/height age. In contrast, BA-adjustment of @entity79 was not useful in this population. Individual @entity79 results may be influenced by gonadal function, transplantation status, and prolonged glucocorticoid therapy.

Bone mineral density is normal in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['child', 'children', 'patients', 'Children'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity3800 :: ('MESH:D000728', 'Chemical') :: ['androgens'] @entity11807 :: ('MESH:D005199', 'Disease') :: ['Fanconi anemia', 'FA']
@entity11807 :: (MESH:D005199,Disease) :: ['Fanconi anemia']
