BACKGROUND _ AIMS: The amount of drug-loaded lipiodol in an @entity5 (TACE) correlates with the risk of local @entity5 recurrence. Lipiodol enhancement of a @entity5 on conventional CT, measured in Hounsfield units (HU), can predict @entity5 response. Here we investigate whether cone-beam CT (CBCT) can also be used to predict @entity5 response, providing the benefit of being able to optimize the @entity1 's treatment plan intra-procedurally. METHODS: A total of 82 @entity157 nodules (82 @entity1 ),  <=5 cm in diameter, were treated with balloon-occluded TACE using @entity58900 between December 2013 and November 2014. For each @entity1 , both CBCT and conventional CT images were obtained post-TACE. The degree of correlation between CBCT and conventional CT was determined by comparing identical regions of interest for each imaging modality using pixel values. RESULTS: The pixel values from conventional CT and CBCT were highly correlated, with a Pearson correlation coefficient of 0.912 (p<0.001). The location of the nodules within the liver did not affect the results; the correlation coefficient was 0.891 (p<0.001) for the left lobe and 0.926 (p<0.001) for the right lobe. The mean pixel value for conventional CT was 439    279 HU, and the mean pixel value for CBCT was 416    311 HU. CONCLUSIONS: CBCT may be used as a substitute for conventional CT to quantitatively evaluate the amount of drug-loaded lipiodol within an @entity157 nodule and, hence, the efficacy of TACE treatment. The major benefit of using CBCT is the ability to predict the likelihood of local recurrence intra-procedurally, enabling subsequent treatment optimization.

Cone-Beam Computed Tomography Correlates with Conventional Helical Computed Tomography in Evaluation of Lipiodol Accumulation in XXXX after Chemoembolization.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'HCC tumor post-transarterial chemoembolization'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC'] @entity58900 :: ('MESH:C406530', 'Chemical') :: ['miriplatin']
@entity157 :: (MESH:D006528,Disease) :: ['HCC']
