Ethyl-1-(14)C-ethion and some of its degradation products have been prepared for comparison purposes. @entity2708 plants were treated with (14)C-ethion alone and in the presence of @entity316 and dimilin pesticides under conditions simulating local agricultural practice. @entity3209 -Residues in seeds were determined at harvest time; about 47.5% of @entity3209 -activity was associated with oil. After further extraction of seeds with @entity1068 , the @entity1068 -soluble @entity3209 -residues accounted for 10.6% of the total seed residues, whereas the cake contained about 37.3% of the total residues as bound residues in the case of @entity21097 only. The bound residues decreased in the presence of @entity316 and dimilin pesticides and amounted to 8.1 and 10.4% of the total residues, respectively. About 95% of the @entity3209 -activity in the crude oil could be eliminated by simulated commercial processes locally used for oil refining. Chromatographic analysis of crude @entity2708 oil revealed the presence of @entity21097 monooxon, @entity68491 , and O,O-diethyl phosphoric acid in addition to one unknown compound in the case of @entity21097 alone or @entity21097 and dimilin. The same degradation products are found in the case of @entity21097 and @entity316 in addition to @entity68492 , whereas @entity1068 extract revealed the presence of @entity68492 and O,O-diethyl phosphoric acid as free metabolites. Acid hydrolysis of the conjugated metabolites in the @entity1068 extract yielded O,O-diethyl S-hydroxymethyl phosphorodithioate. The bound residues were quite readily bioavailable to the @entity35 . After feeding @entity35 with the cake containing @entity21097 -bound residues, a substantial amount (60%) of @entity3209 -residues was eliminated in the urine, whereas the @entity3209 -residues excreted in expired air and feces were 10 and 9%, respectively. About 11% of the radioactive residues were distributed among various organs.

Fate of (14)c-ethion insecticide in the presence of @entity316 and dimilin pesticides in XXXX seeds and oils, removal of @entity21097 residues in oils, and bioavailability of its bound residues to experimental animals.

@entity68491 :: ('MESH:C041609', 'Chemical') :: ['O,O-diethyl phosphorothioate'] @entity21097 :: ('MESH:C100038', 'Chemical') :: ['ethion'] @entity2708 :: ('3635', 'Species') :: ['cotton', 'Cotton'] @entity68492 :: ('MESH:C010141', 'Chemical') :: ['ethion dioxon'] @entity3209 :: ('CHEBI:36927', 'Chemical') :: ['(14)C'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity316 :: ('MESH:C017180', 'Chemical') :: ['deltamethrin'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol']
@entity2708 :: (3635,Species) :: ['cotton']
