UNASSIGNED: In a prospective community-based cohort study, we investigated the relationship between @entity79 ( @entity79 ) and regional fat depots in 1474 Korean postmenopausal @entity1 . @entity79 was positively related with subcutaneous fat and negatively related with visceral fat. INTRODUCTION: The effect of fat distribution (visceral/subcutaneous) on bone quality or microarchitecture has rarely been investigated due to measurement difficulty. We aimed to investigate the relationship between @entity79 reflecting bone microarchitecture and regional fat depots in Korean @entity1 . METHODS: Cross-sectional data evaluation was made from subjects participating in an ongoing prospective community-based cohort study since 2001. A total of 1474 postmenopausal @entity1 in the Ansung cohort were analyzed. Regional body fat mass, bone mineral density (BMD) at the lumbar spine, and total hip and lumbar spine @entity79 were measured by dual energy X-ray absorptiometry (DXA). RESULTS: In an age-adjusted partial correlation analysis, @entity79 was not associated with total fat mass, but negatively associated with trunk fat mass. However, @entity79 was positively related with leg (r   =   0.102, P   <   0.05) and gynoid fat mass (r   =   0.086, P   <   0.05) and negatively related with android fat mass (r   =   -0.106; P   <   0.05). In linear regression models controlling age, BMI, and physical activity, android fat was inversely associated with @entity79 (b   =   -0.595, P   <   0.001), whereas gynoid fat was positively associated with @entity79 (b   =   0.216, P   <   0.001). Lumbar spine and total hip BMDs revealed positive associations with total and all regional fat depots regardless of fat distribution. CONCLUSION: Our findings suggest that relatively large visceral fat and small subcutaneous fat may have a detrimental effect on @entity79 , a bone microarchitecture index.

Regional body fat depots differently affect bone microarchitecture in postmenopausal Korean XXXX .

@entity1 :: ('9606', 'Species') :: ['women'] @entity79 :: ('MESH:D001847', 'Disease') :: ['trabecular bone score', 'TBS']
@entity1 :: (9606,Species) :: ['women']
