OBJECT @entity286 smoking is one of the most important risk factors for the formation of @entity438 and for @entity510 . Smoking has also been suggested to contribute to the recurrence of @entity439 after endovascular coiling. To improve the understanding of the impact of smoking on long-term outcomes after coil embolization of @entity438 , the authors studied a consecutive contemporary series of @entity1 treated at their institution. The aims of this study were to determine whether smoking is an independent risk factor for @entity439 and retreatment after endovascular coiling. METHODS All @entity1 who had received an intrasaccular coil embolization of an @entity438 , who had undergone a follow-up imaging exam at least 6 months later, and whose smoking history had been recorded from January 2005 through December 2012 were included in this study. @entity1 were stratified according to smoking status into 3 groups: 1) never a smoker, 2) current smoker (smoked at the time of treatment), and 3) former smoker (quit smoking before treatment). The 2 primary outcomes studied were @entity439 and @entity439 retreatment after treatment for @entity439 . Kruskal-Wallis and chi-square tests were used to test statistical significance of differences in the rates of @entity439 , retreatment, or of both among the 3 groups. A multivariate logistic regression analysis controlling for smoking status and for several characteristics of the @entity439 was also performed. RESULTS In total, 384 @entity1 with a combined total of 411 @entity439 were included in this study. The @entity439 rate was not significantly associated with smoking: both former smokers (OR 1.00, 95% CI 0.61-1.65; p = 0.99) and current smokers (OR 0.58, 95% CI 0.31-1.09; p = 0.09) had odds of recurrence that were similar to those who were never smokers. Former smokers (OR 0.78, 95% CI 0.46-1.35; p = 0.38) had odds of retreatment similar to those of never smokers, and current smokers had a lower odds of undergoing retreatment (OR 0.44, 95% CI 0.21-0.91; p = 0.03) than never smokers. Moreover, an analysis adjusting for @entity1756 , diameter, and initial occlusion showed that former smokers (OR 0.65, 95% CI 0.33-1.28; p = 0.21) and current smokers (OR 1.04, 95% CI 0.60-1.81; p = 0.88) had odds of @entity439 similar to those who were never smokers. Adjusting the analysis for @entity1756 , diameter, and occlusion showed that both former smokers (OR 0.49, 95% CI 0.23-1.05; p = 0.07) and current smokers (OR 0.82, 95% CI 0.46-1.46; p = 0.50) had odds of retreatment similar to those of @entity1 who were never smokers. CONCLUSIONS The results show that smoking was not an independent risk factor for @entity439 and @entity439 retreatment among @entity1 receiving endovascular treatment for @entity438 at the authors' institution. Nonetheless, @entity1 with @entity438 should continue to be counseled about the risks of @entity286 smoking.

Smoking is not associated with recurrence and retreatment of XXXX after endovascular coiling.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity286 :: ('4097', 'Species') :: ['tobacco', 'Tobacco'] @entity510 :: ('MESH:D013345', 'Disease') :: ['aneurysmal subarachnoid hemorrhages'] @entity1756 :: ('MESH:D017542', 'Disease') :: ['aneurysm rupture'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms', 'aneurysm recurrence', 'aneurysm', 'endovascular aneurysms'] @entity438 :: ('MESH:D002532', 'Disease') :: ['intracranial aneurysm', 'intracranial aneurysms']
@entity438 :: (MESH:D002532,Disease) :: ['intracranial aneurysms']
