OBJECTIVE: To evaluate cosmesis, body image, @entity158 , and quality of life (QoL) after single-port laparoscopic cholecystectomy (SPLC) versus conventional 4-port laparoscopic cholecystectomy (4PLC). BACKGROUND: The impact of SPLC on improving cosmesis, body image, @entity158 , and QoL has not been evaluated in double-blinded @entity23 ( @entity23 ). This approach therefore remains controversial. METHODS: Between October 2011 and February 2014, 110 @entity1 from 2 centers were randomly assigned to SPLC (n=55) or 4PLC (n=55). Primary endpoints were a validated cosmesis (3-24 points) and body image (5-20 points) score after 3 and 12 months. Secondary endpoints included operative duration, @entity282 , complications, QoL, and length of hospital stay. @entity1 , physicians, and nurses were blinded until the seventh postoperative day. RESULTS: Demographics were equally distributed between both groups (mean age: 46 years, @entity168 : 14, 62 females, 34 males). The SPLC-group showed superior mean cosmesis and body image compared with the 4PLC-group at 12-weeks (21 vs 16, P<0.001 and 5 vs 6, P=0.013, respectively) and at 1-year (24 vs 16, P<0.001 and 5 vs 6, P<0.017, respectively). Operation duration was longer in the SPLC-group (mean 101 vs 90 minutes, p=0.031). Although @entity282 was less in the SPLC-group (mean VAS 1 vs 2, p=0.005), there were no differences in complications, and length of hospital-stay. CONCLUSIONS: This is the first multicenter double-blinded @entity23 reporting superior short- and long-term cosmetic and body image, @entity282 , and QoL in SPLC compared with 4PLC. Although cost-effectiveness is still a subject of ongoing debate, SPLC should be offered to @entity1 undergoing surgery for benign @entity1085 .

Cosmesis and Body Image in XXXX Undergoing Single-port Versus Conventional Laparoscopic Cholecystectomy: A Multicenter Double-blinded Randomized Controlled Trial (SPOCC-trial).

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1085 :: ('MESH:D005705', 'Disease') :: ['gallbladder disease'] @entity168 :: ('MESH:D029461', 'Disease') :: ['SD'] @entity23 :: ('MESH:D007174', 'Disease') :: ['RCT', 'randomized controlled trials'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain']
@entity1 :: (9606,Species) :: ['Patients']
