BACKGROUND AND STUDY AIMS: Whereas data on moderate nurse-administered @entity1875 sedation (NAPS) efficacy and safety for standard endoscopy is abundant, few reports on the use of deep sedation by endoscopy nurses during advanced endoscopy, such as @entity10747 ( @entity10747 ) and Endoscopic Ultrasound (EUS) are available and potential benefits or hazards remain unclear. The aims of this study were to investigate the efficacy of intermittent deep sedation with @entity1875 for a large cohort of advanced endoscopies and to provide data on the safety. @entity1 AND METHODS: All available data from @entity1 sedated with intermittent deep NAPS for @entity10747 , EUS or double balloon enteroscopy (DBE, since the method was implemented in May 2007 through December 2012 were included for evaluation in a retrospective case-control design. RESULTS: Data from 1899 @entity1 undergoing 1899 procedures were included for evaluation. All but one procedure were completed with intermittent deep NAPS.The mean @entity1875 dose was 397mg (SD: 232.4) and the infusion rate was 23.9mg/kg. The frequency of @entity519 was 4.3% and 20 @entity1 needed assisted ventilation (1.1%). Anesthesiologic support was requested eight times (0.4%). One @entity1 was intubated due to suspected aspiration. CONCLUSIONS: Intermittent deep NAPS for advanced endoscopies in selected @entity1 provided an almost 100% success rate. However, the rate of @entity519 , @entity551 and respiratory support was high compared with previously published data, but the method was still assessed as safe.

High efficacy with deep nurse-administered XXXX sedation for advanced gastroenterologic endoscopic procedures.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity10747 :: ('MESH:D012183', 'Disease') :: ['Endoscopic Retrograde Cholangiopancreatography', 'ERCP'] @entity519 :: ('MESH:D000860', 'Disease') :: ['hypoxia'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension']
@entity1875 :: (MESH:D015742,Chemical) :: ['propofol']
