BACKGROUND: In endoscopic sinus surgery, visualization of the surgical field is a major concern, as surgical @entity548 is the cause of many complications. The purpose of this study was to compare the effects of @entity6948 and @entity1937 on the visualization of the surgical field in endoscopic sinus surgery. METHODS: Forty-three @entity1 were prospectively enrolled and randomly allocated to the @entity6948 or @entity1937 group and general anesthesia was induced and maintained using a @entity1875 target-controlled infusion. In the @entity6948 group, @entity6948 was loaded for 5 min and a continuous infusion was administered. In the @entity1937 group, a @entity1937 target-controlled infusion was used. After completion of the operation, the satisfaction with the visualization of the surgical field was assessed on a numeric rating scale, from 0 (= worst) to 10 (= best). The mean blood pressure, heart rate, recovery profiles, and @entity282 score were recorded. RESULTS: Satisfaction score for visualization by numeric rating scale was not significantly different between the two groups (P = 0.95). There were no differences in the mean blood pressure and heart rate. The extubation time was significantly shorter in the @entity6948 group (8.4    1.8 min) than in the @entity1937 group (11.9    5.4 min) (P = 0.04). Except for the extubation time, the recovery profiles of the two groups were comparable. CONCLUSIONS: Continuous infusions of @entity6948 provide a similar visualization of the surgical field and hemodynamic stability as @entity1937 target-controlled infusions in @entity1 undergoing endoscopic sinus surgery.

Efficacy of intraoperative XXXX infusion on visualization of the surgical field in endoscopic sinus surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity6948 :: ('MESH:D020927', 'Chemical') :: ['dexmedetomidine'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity1937 :: ('MESH:C071741', 'Chemical') :: ['remifentanil']
@entity6948 :: (MESH:D020927,Chemical) :: ['dexmedetomidine']
