OBJECTIVE: To characterize clinical and pathologic characteristics of @entity189 of the cervix. METHODS: We retrospectively reviewed the charts of @entity1 with @entity189 of the cervix identified by query of the Snomed pathologic diagnostic retrieval system and by direct physician query. Data were extracted from available charts, and pathology review was performed on all cases. SPSS was used for statistical analysis. RESULTS: Nine of 12 identified @entity1 had complete clinical information and pathologic material available. The mean age at diagnosis was 48 (range, 29-76) years. Stage at diagnosis was I (4 @entity1 ), II (2 @entity1 ), and IV (3 @entity1 ). @entity1 younger than 40 years of age presented with stage I disease. All @entity1 had visible @entity5 ; 8 of 9 had @entity3556 or discharge at presentation. Microscopic evaluation revealed areas of spindle-cell @entity5 confluent with areas of poorly differentiated @entity957 . Immunohistochemistry demonstrated coexpression of cytokeratin and @entity2277 in @entity5 cells. @entity5 with a prominent spindle-cell component also expressed smooth muscle actin. Initial treatment varied, but all @entity1 had a complete response to initial treatment. Five @entity1 recurred with a median disease-free interval of 4.9 (range, 2-9.5) months, and none responded to second-line therapy. Four @entity1 remained disease-free at 5, 18, 30, and 40 months, respectively, after completing initial therapy. CONCLUSIONS: @entity189 of the cervix is an aggressive @entity5 . Primary treatment offers the best chance for cure in @entity1 with @entity5 . @entity1 with @entity1442 at presentation or recurrence succumb to their disease.

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@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity3556 :: ('MESH:D014592', 'Disease') :: ['vaginal bleeding'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumors', 'sarcomatous tumor', 'early-stage disease', 'neoplasm'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['sarcomatoid carcinoma', 'Sarcomatoid carcinoma'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['advanced disease'] @entity2277 :: ('7431', 'Gene') :: ['vimentin']
@entity189 :: (MESH:D002277,Disease) :: ['Sarcomatoid carcinoma']
