OBJECTIVES: To estimate the proportion of @entity1 with @entity164 2 @entity6 who were eligible for @entity1780 treatment per American @entity6 Association (ADA) recommendations and the proportion who were actually prescribed a @entity1780 in US clinical practice. Factors associated with receiving a @entity1780 prescription were also determined. METHODS: @entity1 >=  25 years diagnosed with @entity164 2 @entity6 or had received prescriptions for antihyperglycemic agents between 7/2006 and 6/2008 were identified within a large electronic medical record database. Eligibility for @entity1780 therapy was determined according to 2008 ADA recommendations. @entity1780 use was assessed based on prescription records during a 12-month follow-up period. An adjusted logistic regression analysis was performed to estimate the likelihood of @entity1780 use in relation to selected baseline characteristics. RESULTS: Of the 125,464 @entity1 identified, 98.5% were eligible for @entity1780 therapy. Only 62.9% received a @entity1780 prescription during follow-up period. In an adjusted logistic regression, factors associated with increased likelihood of @entity1780 use were older age, male gender, smoking, history of @entity65 , and receiving an antihyperglycemic, antihypertensive, or anticoagulant prescription at baseline (all p < 0.05). LIMITATIONS: Of the @entity1 who did not receive @entity1780 during follow-up, 13% of them were previously on a @entity1780 during the baseline period. The reasons for discontinuing therapy are not known. It cannot be excluded that some of these @entity1 were intolerant or had contraindications to @entity1780 . The data on prescription dispensing and compliance were not recorded. CONCLUSIONS: Nearly all @entity1 with @entity164 2 @entity6 were eligible for @entity1780 therapy, but less than two-thirds received @entity1780 therapy in US clinical practice. Efforts to minimize this gap are warranted.

Underutilization of statins in XXXX with @entity164 2 @entity6 in US clinical practice: a retrospective cohort study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetes'] @entity1780 :: ('CHEBI:35664', 'Chemical') :: ['statin', 'Statin'] @entity164 :: ('MESH:D017827', 'Disease') :: ['type'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular conditions']
@entity1 :: (9606,Species) :: ['patients']
