OBJECTIVES: Incomplete initial surgery complicates subsequent management of early-stage @entity43 (ESEOC). This study aimed to determine the most appropriate strategies for individualized treatment of these @entity1 . METHODS: Medical records of ESEOC @entity1 treated at our hospital between 2000 and 2011 were reviewed, and 246 @entity1 initially treated by incomplete surgery were included. A scoring system was established to assess the quality of initial surgery (QOIS). RESULTS: Of 246 @entity1 , 130 underwent restaging surgery and 116 received chemotherapy only. Follow-up duration ranged from 4 to 148 months (median, 72 months). The 5-year @entity1349 ( @entity1349 ) rates were 87.5% and 74.7% in the restaging and chemotherapy groups, respectively. Survival analysis showed significantly better @entity1349 ( @entity1349 ) and @entity1349 in the restaging group (P = 0.043 and P = 0.029, respectively). Multivariate analysis showed that histologic grade was an independent predictor for @entity1349 and @entity1349 in the restaging group (P = 0.035 and P = 0.038, respectively), and histologic grade (P = 0.005 and P = 0.015, respectively) and QOIS (P = 0.044 and P = 0.024, respectively) were independent predictors for @entity1349 and @entity1349 in the chemotherapy group. Subgroup analysis showed that restaging surgery produced better @entity1349 and @entity1349 than chemotherapy in @entity1 with low QOIS and unfavorable histology (5-year @entity1349 , 58.5% vs 33.4%, P = 0.007; 5-year @entity1349 , 82.2% vs 54.4%, P = 0.011), whereas the outcomes between the treatment options were comparable in @entity1 with high QOIS or favorable histology. CONCLUSIONS: Our results support individualized treatment of ESEOC @entity1 initially treated by incomplete surgery. Restaging surgery is recommended only for @entity1 with low QOIS and unfavorable histology.

Individualized Treatment of XXXX With Early-Stage Epithelial Ovarian Cancer After Incomplete Initial Surgery.

@entity43 :: ('MESH:D010051', 'Disease') :: ['epithelial ovarian carcinoma'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'RFS', 'recurrence-free survival', 'overall survival']
@entity1 :: (9606,Species) :: ['Patients']
