OBJECTIVE: The aim of this prospective study was to determine whether a @entity1 population with low overall @entity1547 frequency benefits when prevention is targeted to high-risk individuals. METHODS: Data from clinical examinations and salivary tests were used to assess @entity1547 risk in 12-year-olds (n=1465). @entity1 who were regarded as being at high risk of developing @entity1547 were randomized into two groups. Half ( @entity37623 group) were offered intensive prevention (counseling, F-varnish applications, F-lozenges, sealants, @entity1216 ), and the other half ( @entity61423 group) were provided the same basic prevention given to low-risk @entity1 (counseling, one F-varnish application/year). A random sample of the low-risk @entity1 (LRB) was followed up for the same 3-year period as the high-risk @entity1 . The number of @entity1 completing the study was 216 in the LRB group, 199 in the @entity37623 group and 174 in the @entity61423 group. RESULTS: The mean (SD) 3-year DMFS increment was 2.0 (2.4), 4.4 (4.7) and 5.1 (5.0) in the LRB, @entity37623 and @entity61423 groups, respectively. Comparison between the LRB and @entity61423 groups revealed that risk assessment was fairly successful in terms of mean DMFS increment. However, 63% of the @entity1 in the LRB group developed at least one new lesion (max. 12). CONCLUSIONS: The negligible difference between the @entity37623 and @entity61423 groups implies that intensifying prevention produced practically no additional benefit. By offering all @entity1 only basic prevention, virtually the same preventive effect could have been obtained with substantially less effort and lower costs.

Application of the high-risk strategy to control dental XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Children', 'child'] @entity37623 :: ('27102', 'Gene') :: ['HRI'] @entity1216 :: ('MESH:D002710', 'Chemical') :: ['chlorhexidine'] @entity61423 :: ('3267', 'Gene') :: ['HRB'] @entity1547 :: ('MESH:D003731', 'Disease') :: ['caries']
@entity1547 :: (MESH:D003731,Disease) :: ['caries']
