BACKGROUND: Previous reports suggest that donation after @entity204 (DCD) liver grafts have increased primary nonfunction (PNF) and cholangiopathy thought to be due to the graft warm @entity63 before cold flushing. STUDY DESIGN: In this single-center, retrospective study, 866 adult liver transplantations were performed at our institution from January 2005 to August 2014. Forty-nine (5.7%) @entity1 received DCD donor grafts. The 49 DCD graft recipients were compared with all recipients of donation after @entity1620 donor (DBD) grafts and to a donor and recipient age- and size-matched cohort. RESULTS: The DCD donors were younger (age 28, range 8 to 60 years) than non-DCD (age 44.3, range 9 to 80 years) (p < 0.0001), with similar recipient age. The mean laboratory @entity3851 ( @entity3851 ) was lower in DCD recipients (18.7 vs 22.2, p = 0.03). Mean cold and warm @entity63 times were similar. Median ICU and hospital stay were 2 days and 7.5 days in both groups (p = 0.37). Median follow-ups were 4.0 and 3.4 years, respectively. Long-term outcomes were similar between groups, with similar 1-, 3- and 5-year @entity1 and graft survivals (p = 0.59). Four (8.5%) recipients developed @entity63 ( @entity63 ) at 2, 3, 6, and 8 months. Primary nonfunction and @entity715 did not occur in any @entity1 in the DCD group. @entity810 was more common with DCD grafts (16.3% of DCD recipients required dialysis vs 4.1% of DBD recipients, p = 0.01). An increased donor age (>40 years) was shown to increase the risk of @entity63 (p = 0.006). CONCLUSIONS: Careful selection of DCD donors can provide suitable donors, with results of liver transplantation comparable to those with standard brain dead donors.

Outcomes Using Grafts from Donors after XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic cholangiopathy', 'IC', 'ischemia'] @entity1620 :: ('MESH:D001926', 'Disease') :: ['brain death'] @entity3851 :: ('MESH:D058625', 'Disease') :: ['MELD', 'Model for End-Stage Liver Disease'] @entity810 :: ('MESH:D058186', 'Disease') :: ['Acute kidney injury'] @entity715 :: ('MESH:D013927', 'Disease') :: ['hepatic artery thrombosis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['cardiac death']
@entity204 :: (MESH:D003643,Disease) :: ['Cardiac Death']
