BACKGROUND: Periodontal ligament (PDL) healing and long term prognosis of replanted avulsed teeth should rely on several factors including length of extra-oral dry time and type of the storage medium. The status of periodontal ligament is critical for the healing of replanted teeth. Different substances have been used for root surface treatment to promote formation of PDL and increase the survival of avulsed teeth submitted to replantation. AIM: The purpose of this study was to assess the effect of recombinant @entity24976 ( @entity24976 ) and @entity2193 ( @entity2193 ) on root resorption after delayed replantation. DESIGN: 18 freshly extracted single-rooted incisor and premolar teeth were extracted from the @entity235 and immersed in whole @entity291 milk for 45 and 60  min (n  =  3 each). Following storage period, sockets washed and teeth were treated with @entity24976 and @entity2193 and replanted into the sockets. After 8  weeks, @entity235 were sacrificed, specimens processed to 4- m thick serial sections for histopathologic examination and morphometric assessments. Thus, the proportions of the roots that exhibited signs of surface resorption, inflammatory resorption, and replacement resorption, that is, @entity3947 and normal PDL were noted. RESULTS: The percentage of root resorption was in the following order: @entity2193 >milk> @entity24976 for 45 min and milk> @entity2193 > @entity24976 for 60  min. For all groups, teeth stored 60  min showed significantly higher incidence of PDL resorption than those stored for 45  min (P  <  0.01). The highest incidence of replacement resorption was observed in teeth treated with @entity2193 for 60  min. After 8  weeks, the least resorption was found in @entity24976 -treated group (P  <  0.01). CONCLUSIONS: The findings of this study suggest that use of @entity24976 favored the formation of new periodontal ligament; prevent @entity3947 and resorption process following delayed replantation of teeth while @entity2193 shows replacement resorption, which may turn to @entity3947 .

Effect of fibroblast growth factor and XXXX treatment on root resorption after delayed replantation.

@entity235 :: ('9615', 'Species') :: ['beagle dogs', 'dogs'] @entity3947 :: ('MESH:D000844', 'Disease') :: ['ankylosis'] @entity24976 :: ('403857(Tax:9615)', 'Gene') :: ['bFGF', 'basic fibroblast growth factor 2'] @entity2193 :: ('MESH:D003744', 'Disease') :: ['enamel matrix derivative', 'EMD'] @entity291 :: ('9913', 'Species') :: ['bovine']
@entity2193 :: (MESH:D003744,Disease) :: ['enamel matrix derivative']
