The concomitant boost technique is a variant of accelerated fractionation whereby the boost is delivered as a second daily fraction during the basic treatment course to reduce the total duration of treatment. From April 1972 through June 1983, 53 @entity1 with @entity957 of various sites in the @entity135 region were treated for cure at U.T. M. D. Anderson Hospital with this technique. In 12 @entity1 , the concomitant boost was used because of rapid recurrence following surgical resection either before or after initiation of planned postoperative radiotherapy; the remaining @entity1 had rapidly growing untreated or recurrent disease in the primary site, neck, or both. In most cases, the concomitant boost was delivered in fractions of 120-150 cGy, separated by 3-6 h from the basic daily treatment of 180-200 cGy. The boost treatments were given 2-3 times a week for 3-5 weeks, delivering an average of about 17 Gy in 12 fractions. Two different treatment techniques were used. @entity1 with @entity135 (30) were treated with glancing AP and PA fields or with appositional electron beam portals to spare the mucous membranes, while those with advanced or rapidly progressive @entity75 , with or without @entity66 (23), received their concomitant boost through lateral photon or high energy electron beams to include the primary @entity5 site. As expected, the @entity33 were most severe in the latter group, but only three @entity1 required interruption of treatment because of severe @entity33 .(ABSTRACT TRUNCATED AT 250 WORDS)

Concomitant boost radiotherapy for XXXX of the @entity135 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity135 :: ('MESH:D006258', 'Disease') :: ['predominantly neck disease', 'head and neck'] @entity66 :: ('MESH:D004194', 'Disease') :: ['nodal disease'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesions'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity957 :: ('MESH:D002294', 'Disease') :: ['advanced squamous cell carcinoma'] @entity33 :: ('MESH:D052016', 'Disease') :: ['acute mucosal reactions', 'mucositis']
@entity957 :: (MESH:D002294,Disease) :: ['advanced squamous cell carcinoma']
