BACKGROUND: @entity1151 ( @entity1151 ) is a common condition managed in the @entity341 ( @entity341 ), with a wide range of morbidity and mortality. @entity1 are classically admitted for treatment and monitoring of anticoagulation. OBJECTIVE: We sought to evaluate the controversy concerning outpatient therapy for @entity1 with acute @entity1151 and investigate the feasibility, safety, and efficacy of outpatient management. DISCUSSION: @entity1 with @entity1211 have historically been admitted for treatment and monitoring for concern of worsening disease or side effects of anticoagulation ( @entity548 ). More than 90% of EDs admit @entity1 with @entity1151 in the United States. However, close to  50% of @entity1 may be appropriate for discharge and outpatient therapy. The published literature suggests that outpatient treatment is safe, feasible, and efficacious, with similar rates of recurrent @entity1211 and all-cause mortality, especially with novel oral anticoagulants. Multiple scoring criteria can be used, including the @entity1151 Severity Index (PESI), simplified PESI, Hestia criteria, Geneva Prognostic Score, European Society of Cardiology guidelines, Global Registry of Acute Coronary Events, and Aujesky score. Simplified PESI and the European Society of Cardiology guidelines have high-quality evidence, sufficient sensitivity, and ease of use for the @entity341 . @entity1 considered for outpatient therapy should possess low @entity548 risk, adequate social situation, negative biomarkers, ability to comply, and no alternate need for admission. CONCLUSIONS: @entity1 with acute @entity1151 are often admitted in the United States, but a significant proportion may be appropriate for discharge. @entity1 with low risk for adverse events according to clinical scoring criteria, adequate follow-up, ability to comply, and no other need for admission can be discharged with novel oral anticoagulant therapy.

Best Clinical Practice: Controversies in Outpatient Management of Acute XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding', 'hemorrhage'] @entity341 :: ('MESH:D004630', 'Disease') :: ['emergency department', 'ED'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['Pulmonary embolism', 'PE', 'Pulmonary Embolism'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thromboembolism']
@entity1151 :: (MESH:D011655,Disease) :: ['Pulmonary Embolism']
