Nutritional status was evaluated on 210 occasions in 90 pediatric oncology inpatients during a 7-month period; 39 had solid @entity5 and 51 @entity1778 . Ages ranged from 3 months to 20 yr. Nutritional parameters were defined as normal, "at risk," or "probably malnourished." Fifty-seven and 29% of assessments revealed at least one parameter "at risk" or "probably malnourished," respectively. Prognosis was negatively related to the number of abnormal nutritional parameters. Serum @entity2313 was most frequently abnormal. However, on most occasions, @entity4988 was associated with weight/height, arm muscle area, and triceps skinfold measurements in the normal range. In order to further identify determinants of serum @entity2313 , we analyzed dietary, chemotherapy, and temperature data in 10 prospectively studied @entity1778 @entity1 , half of whom received parenteral nutrition. In these @entity1 there was little relationship of serum @entity2313 to chemotherapy or dietary intake. In all of these @entity1 , especially those receiving total parenteral nutrition, low serum @entity2313 was highly associated with fever (p less than 0.0005). We concluded that @entity221 is an important determinant of abnormal serum @entity2313 concentrations. In @entity5 patients, abnormal serum @entity2313 may more often reflect the acute metabolic response to fever and @entity281 than depletion of body mass.

Significance of XXXX in pediatric oncology @entity1 --malnutrition or @entity281 ?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2313 :: ('213', 'Gene') :: ['albumin'] @entity4988 :: ('MESH:D034141', 'Disease') :: ['hypoalbuminemia'] @entity5 :: ('MESH:D009369', 'Disease') :: ['pediatric cancer', 'tumors'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['leukemia'] @entity221 :: ('MESH:D005334', 'Disease') :: ['febrile illness']
@entity4988 :: (MESH:D034141,Disease) :: ['hypoalbuminemia']
