BACKGROUND: Although @entity28 is a well-known risk factor for complications in immediate expander-implant breast reconstruction, no studies have identified risk factors for @entity28 @entity1 . The purpose of this study was to identify risk factors for complications in @entity28 @entity1 . METHODS: A retrospective analysis of prospectively collected data from 397 consecutive immediate expander-implant breast reconstructions in 367 @entity28 @entity1 at a single institution over a 5-year period was conducted. Univariable and multivariable analysis were performed to determine the influence of six @entity1 -related and eight procedure-related characteristics on complications. RESULTS: Mean BMI was 21.7      2  kg/m(2) and median mastectomy weight was 298.0  g (range: 40-1164  g). Multivariable analysis showed that neither BMI nor the use of acellular dermal matrix was a predictor for complications. Adjuvant radiation (odds  =  3.12, p  <  0.001) and mastectomy weight (p  <  0.001) were independent risk factors for complications. A 100  g increase in the mastectomy weight was significantly associated with a 23  % increase in the odds of overall complications (p  =  0.003), major complications (p  =  0.004), and skin flap complications (p  =  0.007), as well as a 28  % increase in the odds of @entity2080 (p  =  0.044), but was not associated with reconstruction failure. Adjuvant radiation (p  <  0.001) and @entity101 (p  <  0.001) were risk factors for reconstruction failure. CONCLUSIONS: Breast size was an independent risk factor for complications in @entity28 @entity1 while BMI was not. In the reconstruction of large breasts, greater attention and additional adjunctive procedures would be needed to prevent complications. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Risk Factors for Complications in Immediate Expander-Implant Breast Reconstruction for Non-obese XXXX : Impact of Breast Size on Complications.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2080 :: ('MESH:D049291', 'Disease') :: ['seroma'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity', 'non-obese']
@entity1 :: (9606,Species) :: ['Patients']
