Three cases of @entity816 ( @entity816 ) in the @entity1 aged 23, 26, and 36 years were reported. Two of them had no clinical evidence of @entity2916 ( @entity2916 ) and the one @entity1 presented apparent @entity1032 . All @entity1 manifested sudden clinical onset with symptoms of @entity428 due to @entity5 of lateral ventricles and obstructive @entity1276 . At surgery, the @entity5 was removed totally in one case and resected partially in 2 cases. Histologically, the @entity5 were composed of large polygonal cells with vesicular nuclei, prominent nucleoli and glassy eosinophilic cytoplasm, intermingled with spindle and small cells. In addition, multinucleated and bizarre giant cells were present, but they were very numerous in one case only. The @entity5 cells revealed in all cases variegated immunoreactivity for @entity538 ( @entity538 ), @entity4483 protein, @entity2277 ( @entity2277 ) and @entity3508 ( @entity3508 ), with stronger expression of @entity2277 than @entity538 in 2 cases. Immunostaining of neurofilament proteins and @entity5473 was negative. The results suggest rather astroglial incomplete or aberrant differentiation and maturation than neuronal differentiation of @entity5 cells. The immunohistochemical variations of @entity816 in asymptomatic @entity2916 cases and those associated with @entity2916 are discussed.

XXXX : clinical, histologic and immunohistochemical characteristic of 3 cases.

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'patients'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['mental retardation'] @entity5473 :: ('6855', 'Gene') :: ['synaptophysin'] @entity1276 :: ('MESH:D006849', 'Disease') :: ['hydrocephalus'] @entity428 :: ('MESH:D019586', 'Disease') :: ['elevated intracranial pressure'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors', 'neoplasm'] @entity538 :: ('2670', 'Gene') :: ['GFAP', 'glial fibrillary acidic protein'] @entity4483 :: ('6285', 'Gene') :: ['S-100'] @entity2916 :: ('MESH:D014402', 'Disease') :: ['tuberous sclerosis', 'tuberous sclerosis complex', 'TSC'] @entity816 :: ('MESH:D001254', 'Disease') :: ['subependymal giant cell astrocytoma', 'SEGA'] @entity2277 :: ('7431', 'Gene') :: ['vimentin', 'VIM'] @entity3508 :: ('2026', 'Gene') :: ['neuron-specific enolase', 'NSE']
@entity816 :: (MESH:D001254,Disease) :: ['Subependymal giant cell astrocytoma']
