The aim of this study is to investigate whether work-related stress symptoms in midlife are associated with a number of mobility limitations during three decades from midlife to late life. Data for the study come from the Finnish Longitudinal Study of Municipal Employees ( @entity1182 ). The study includes a total of 5429 public sector employees aged 44-58  years at baseline who had information available on work-related stress symptoms in 1981 and 1985 and mobility limitation score during the subsequent 28-year follow-up. Four midlife work-related stress profiles were identified: negative reactions to work and @entity308 , perceived decrease in cognition, @entity25 , and somatic symptoms. @entity1 with a high number of stress symptoms in 1981 and 1985 were categorized as having constant stress. The number of self-reported mobility limitations was computed based on an eight-item list of mobility tasks presented to the @entity1 in 1992, 1997, and 2009. Data were analyzed using joint Poisson regression models. The study showed that depending on the stress profile, @entity1 suffering from constant stress in midlife had a higher risk of 30-70  % for having one more mobility limitation during the following 28  years compared to @entity1 without stress after adjusting for mortality, several lifestyle factors, and chronic conditions. A less pronounced risk increase (20-40  %) was observed for @entity1 with occasional symptoms. The study suggests that effective interventions aiming to reduce work-related stress should focus on both primary and secondary prevention.

Work-related stress in midlife is associated with higher number of mobility limitation in older age-results from the XXXX study.

@entity1 :: ('9606', 'Species') :: ['participants', 'persons', 'People'] @entity1182 :: ('8837', 'Gene') :: ['FLAME'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep disturbances'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressiveness']
@entity1182 :: (8837,Gene) :: ['FLAME']
