AIM: to evaluate the serum concentration of NO in overweight @entity1 , smokers (SG) and nonsmokers (NSG). METHODS: blood samples from smokers (n = 20) and nonsmokers (n = 18) were collected to obtain serum, and stored at -80   C until analysis. NO was assessed by measuring total @entity3542 , determined by Greiss method. It was adopted as reference 24.4    mol/L, mean value found in a study with healthy subjects without excess weight. We used the Student t test to compare the means of age and waist circumference, and the Mann-Whitney U test to compare the median of concentrations of @entity3542 , number of cigarettes/day and Body Mass Index. We adopted a significance level of p < 0.05. RESULTS: the median @entity3542 in SG was 16.53 (2.79 - 69.72)    mol/L, whereas in NSG was 10.85 (1.44 - 43.25)    mol/L (p = 0.028). BMI median value to SG and NSG, was respectively 29.50 (25.00 - 38.14) kg/m2 and 30.68 (25.10 - 36.98) kg/m2 (p = 0.530), being classified as overweight. The data showing that the average @entity3542 was below the estimated value for healthy individuals. CONCLUSION: the results indicate a decrease of NO metabolites in @entity1 with excess weight, independently of being smoker. Despite the significant difference found between groups, these @entity1 had values well below the reference value of NO for healthy @entity1 . Therefore, it seems that smoking does not interfere in @entity3542 levels in @entity1 already compromised by @entity28 .

SERUM CONCENTRATION OF NITRIC OXIDE IN XXXX SMOKERS AND NONSMOKERS WITH OVERWEIGHT.

@entity1 :: ('9606', 'Species') :: ['patients', 'women'] @entity3542 :: ('CHEBI:16301', 'Chemical') :: ['nitrite'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity']
@entity1 :: (9606,Species) :: ['WOMEN']
