PURPOSE: We evaluate the outcome, clarify the patterns of failure and suggest treatment strategies for @entity242 in the spermatic cord. MATERIALS AND METHODS: Between 1956 and 1998, 32 @entity1 with spermatic @entity602 were treated at M. D. Anderson @entity5 Center. A retrospective review of disease outcome, patterns of relapse and @entity1 survival was performed. RESULTS: Histological subtypes of @entity242 were @entity1418 in 12 @entity1 , @entity1822 in 6, @entity1821 in 8 and other subtypes in 6. All except 2 @entity1 underwent radical orchiectomy with or without additional resection to achieve negative margins. Margins were microscopically negative in 29 cases and positive in 3. There were 3 @entity1 who received adjuvant radiation to the surgical site. With a median followup of 9 years the 10 and 15-year actuarial local control, distant metastasis-free and overall survival rates were 72% and 61%, 85% and 85%, and 63% and 52%, respectively. The major pattern of failure was local recurrence that occurred in 8 of the 12 @entity1 in whom disease relapsed and was the sole site of relapse in 7. Pelvic nodes had relapsed in 2 @entity1 and para-aortic nodes in 1. Hematogenous metastases had developed in 4 @entity1 . Of the 7 cases of disease that recurred locally only 3 were salvaged. No relapse occurred in the 3 @entity1 treated with combined surgery and radiation. CONCLUSIONS: Spermatic @entity602 has a high propensity for local recurrence after surgery. Nodal relapse is less frequent than commonly believed. Because of the relatively high local failure rate seen in surgery alone and durable local control noted in 3 @entity1 treated with surgery plus radiotherapy, combined modality treatment should be considered in those with spermatic @entity602 who are believed to be at high risk for local failure.

Spermatic XXXX : outcome, patterns of failure and management.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma'] @entity1418 :: ('MESH:D051677', 'Disease') :: ['malignant fibrous histiocytoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cancer'] @entity602 :: ('MESH:D013118', 'Disease') :: ['cord sarcoma'] @entity1822 :: ('MESH:D007890', 'Disease') :: ['leiomyosarcoma'] @entity1821 :: ('MESH:D008080', 'Disease') :: ['liposarcoma']
@entity602 :: (MESH:D013118,Disease) :: ['cord sarcoma']
