INTRODUCTION: 40 to 50% of elderly with @entity173 present @entity933 . The morbimortality increase in @entity1 whose presented @entity933 . OBJECTIVE: To study the use of @entity6624 ( @entity13667 choline) in the prevention of @entity933 in elderly under @entity173 surgery. @entity1 AND METHODS: A randomized control trial. The @entity1 with @entity173 without @entity303 or an other organic brain illness. The medication were administered 24 hours before and during 4 days after surgery. The doses was 1.2 g/day. The primary outcome measure was percentage of @entity1 with @entity933 measured with Abbreviated Mental Test (AMT) and Confusion Assessment Method (CAM). The Mini Mental State (MMS) was used before and 4 days after surgery. All treatment comparation was considered statistically significant at p< 0.05 calculating chi square and Wilcoxon test. RESULTS: The sample size was 81 @entity1 (46 placebo and 35 @entity6624 ). The mean age was 79.45 for tested group and 79.97 for placebo. There was no statistically significant difference between groups with respect to ASA class of anesthesia. The incidence of @entity933 was 17.39% in placebo and 11.76% in @entity6624 group (p= 0.6). CAM and AMT at 1, 2, 3, 4 days post surgery was not significant in placebo and @entity6624 group (p= 0.8 and p= 0.34). CONCLUSION: In the present study the @entity6624 did not prevent or reduce the incidence of @entity933 in @entity173 surgery in elderly.

[Use of procholinergics in the prevention of postoperative delirium in XXXX surgery in the elderly. A randomized controlled trial].

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity173 :: ('MESH:D006620', 'Disease') :: ['hip fracture'] @entity13667 :: ('MESH:D003565', 'Chemical') :: ['CDP'] @entity933 :: ('MESH:D003693', 'Disease') :: ['delirium'] @entity6624 :: ('MESH:D003566', 'Chemical') :: ['citicoline']
@entity173 :: (MESH:D006620,Disease) :: ['hip fracture']
