BACKGROUND: The authors reported previously that assessment of the number of positive biopsy cores, maximum @entity5 length in a core, Gleason score, and prostate volume in an extended biopsy enhanced the accuracy of predicting @entity263 . On the basis of those findings, they developed a nomogram to predict the probability of @entity263 specifically for @entity1 with a single positive biopsy core. METHODS: The study cohort comprised 258 @entity1 who underwent radical prostatectomy without neoadjuvant therapy. @entity263 was diagnosed in only 1 core of an extended biopsy scheme. @entity258 was defined as pathologic organ-confined disease and a @entity5 volume<0.5 cc with no Gleason grade 4 or 5 @entity5 . @entity1 age, @entity1486 level, prostate volume, @entity1486 density (PSAD), and @entity5 length in a biopsy core were examined as variables. A fitted multiple logistic regression model was used to establish the nomogram. RESULTS: One hundred thirty-three @entity1 (51.6%) had @entity258 . To establish the nomogram, age, PSAD, and @entity5 length were adopted as variables. The fitted model suggested that older age, higher PSAD values, and greater @entity5 length would reduce the probability of @entity258 . The nomogram predicted @entity258 with good discrimination (an area under the receiver operating characteristic curve of 0.727). Calibration of this nomogram showed good predicted probability. CONCLUSIONS: The authors established a nomogram with which to predict @entity258 in @entity1 with 1 positive biopsy core in an extended biopsy scheme, and they recommend this nomogram for use in selecting @entity1 for active surveillance.

A nomogram for predicting @entity263 : a tool in selecting XXXX for active surveillance.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient', 'men'] @entity263 :: ('MESH:D011471', 'Disease') :: ['Prostate cancer', 'low-volume/low-grade prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity258 :: ('MESH:D009800', 'Disease') :: ['low-volume/low-grade cancer', 'Low-volume/low-grade cancer'] @entity1486 :: ('354', 'Gene') :: ['prostate-specific antigen (PSA)', 'PSA']
@entity1 :: (9606,Species) :: ['patients']
