This study was aimed at investigating the relationship between serum @entity4090 levels and the morphology of operable female breast lesions. One hundred fifty-three consecutive @entity1 with operable benign and malignant breast lesions in whom preoperative serum @entity4090 levels had been determined were stratified into five groups according to their serum @entity4090 levels. The histologic findings in these groups were analyzed and compared. Most @entity1 (93%) had serum @entity4090 levels within the normal limits. Of the 54 @entity1 with benign lesions, only 4(7%) had slightly elevated serum @entity4090 levels. Two of these @entity1 had @entity1557 , one had a @entity5 and one had @entity3923 . Of the 99 @entity1 with @entity189 , 7 (7%) had @entity4089 . Five of the seven @entity5 were invasive and two were in situ. All seven @entity5 were of low or intermediate grade of @entity5 . The two cases with the highest @entity4090 levels (3057 and 1822 mU/L) were both intermediate-grade @entity3821 ( @entity3821 ). It is concluded that the great majority of @entity1 presenting with operable breast lesions have normal serum @entity4090 levels, and that elevated levels, when present, occur with equal frequency in @entity1 with benign and malignant breast lesions. Hyperprolactinemic @entity1 presenting with @entity189 in this study, none of whom had a history of recent pregnancy or lactation, tended to have histologically low- or intermediate-grade @entity5 , but this needs to be confirmed by investigating more cases.

Relationship between serum XXXX levels and histology of benign and malignant breast lesions: a detailed study of 153 consecutive cases.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4089 :: ('MESH:D006966', 'Disease') :: ['hyperprolactinemia'] @entity3821 :: ('MESH:D002285', 'Disease') :: ['ductal carcinoma in situ', 'DCIS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['phyllodes tumor', 'malignancy', 'tumors'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity4090 :: ('5617', 'Gene') :: ['prolactin'] @entity3923 :: ('MESH:D005348', 'Disease') :: ['fibrocystic change'] @entity1557 :: ('MESH:D018226', 'Disease') :: ['fibroadenomas']
@entity4090 :: (5617,Gene) :: ['prolactin']
