PURPOSE: We investigated the relationship between preoperative quantitative magnetic resonance imaging (MRI) T2 relaxometry and volumetry of the hippocampi and pre- and postoperative verbal memory in temporal lobectomy @entity1 who had nonlesional @entity1315 . METHODS: Pre- and postoperative memory data based on the Logical Memory (LM) subtest of the Wechsler Memory Scale-Revised (WMS-R) and the 30-min delayed recall trial of the Rey Auditory Verbal Learning Test (AVLT) were obtained from 26 left and 15 right temporal lobectomy @entity1 . Coronal MRI T2 maps were generated for these 41 temporal lobectomy @entity1 as well as 61 control @entity1 . Hippocampal T2 relaxation times and hippocampal volumes, converted to z scores using control group data, were correlated with neuropsychological performance in the @entity1 . RESULTS: In left temporal lobe-onset @entity1 , high T2 in the left hippocampal body predicted higher LM performance after surgery. Asymmetrically high T2 in the left hippocampal body (i.e., the right-minus-left difference), compared with the right hippocampal body, also predicted higher LM performance after surgery. In right temporal lobe-onset @entity1 , high T2 in the left hippocampal body predicted relatively lower AVLT performance after surgery. Multiple regression analysis in left temporal-onset @entity1 revealed that high T2 in the left hippocampal body together with higher preoperative LM performance predict higher postoperative LM performance. CONCLUSIONS: Our findings suggest that elevated (i.e., abnormal) hippocampal T2 signal is associated with memory ability (or hippocampal functional capacity) independent of MRI-determined hippocampal atrophy. Therefore, our findings support the use of quantitative T2 relaxometry as an independent predictor of verbal memory outcome in both left and right TLE @entity1 who are candidates for temporal lobectomy.

The relationship between quantitative T2 relaxometry and memory in nonlesional XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1315 :: ('MESH:D004833', 'Disease') :: ['temporal lobe epilepsy']
@entity1315 :: (MESH:D004833,Disease) :: ['temporal lobe epilepsy']
