OBJECTIVE: To compare surgical outcomes between matched @entity6220 ( @entity6220 ) and extended hepatectomy (EH) groups. BACKGROUND: Surgical choices for centrally located @entity96 are limited. The traditional EH harbours substantial risks, whereas @entity6220 is an alternative parenchymal-sparing resection that may improve peri-operative morbidity. METHODS: A review of 4661 liver resections at a single institution was performed. The cases ( @entity6220 ) were matched in a 1:1 ratio with EH controls. RESULTS: The @entity6220 group was matched for @entity5 and laboratory factors with either right EH or combined (right/left) EH groups (n  =  63 per group). Colorectal liver metastases were the most common diagnosis occurring in 70% of the @entity1 . Higher intra-operative @entity190 was observed in the right EH(P  =  0.01) and combined EH groups (P  <  0.01) compared with the @entity6220 group. There was a trend towards lower 90-day morbidity in the @entity6220 group (43%) compared with the right EH(59%, P  =  0.1) and combined EH groups (56%, P  =  0.2). The length of hospital stay was significantly longer in the control groups (P  <  0.01 for both). The control groups had significantly higher post-operative @entity648 and International Normalized Ratio (INR) levels compared with the @entity6220 group. A post-operative @entity648 higher than 4  mg/dl was observed in 2% of the @entity6220 group compared with 39% of the right EH group (P  <  0.01) and 52% of the combined EH group (P  <  0.01). No differences in the rates of @entity1157 /biloma, @entity1578 or 90-day mortality were found. CONCLUSIONS: @entity6220 , as compared with EH, was safe and associated with a shorter hospital stay and less post-operative @entity409 . @entity6220 should be considered in @entity1 with centrally located @entity5 amenable to such a resection.

Central hepatectomy versus extended hepatectomy for XXXX : a matched cohort comparison.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6220 :: ('MESH:D020279', 'Disease') :: ['central hepatectomy', 'CH'] @entity96 :: ('MESH:D008113', 'Disease') :: ['liver tumours'] @entity5 :: ('MESH:D009369', 'Disease') :: ['demographic, tumour', 'tumours'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity648 :: ('MESH:D001663', 'Chemical') :: ['bilirubin'] @entity1157 :: ('MESH:D001649', 'Disease') :: ['bile leak'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver dysfunction'] @entity1578 :: ('MESH:D017093', 'Disease') :: ['post-hepatectomy liver failure']
@entity409 :: (MESH:D008107,Disease) :: ['liver malignancy']
