UNASSIGNED: The objectives of this study were to investigate left ventricular (LV) function, aortic dilation, and @entity731 in @entity1 with mildly deteriorated isolated bicuspid aortic valve (BAV) function using echocardiographic studies and biochemical markers of @entity731 and to correlate results with normal @entity1 . Biochemical analyses indicating @entity65 of @entity731 and vascular changes in the aorta in relation to BAV were performed in 41 @entity1 aged 5-15  years old with isolated BAV and in 25 @entity1 with tricuspid aortic valves. Evaluations of aortic valve structures and functions; examinations of the LV M-mode and ascending aorta Doppler; and measurements of the LV Tei index (MPI), propagation velocity, ascending aorta at four levels, and @entity1004 ( @entity1004 ) were performed. There were no statistically significant differences in CIMTs, plasma @entity1495 , tissue metalloproteinase inhibitor-1 levels, or other biochemical parameters indicating @entity65 or @entity731 between study and control groups. Deterioration of LV function, which could not be seen with M-mode echocardiography, was evident by MPI. MPI values in the study versus control groups were 0.46      0.080 versus 0.40      0.086 (p  <  0.05). Diameters of the aorta in the study and control groups were 19.7      4.7 and 17.2      2.8  mm (p  <  0.05) at the sinotubular junction level and 20.6 (14.4-40.5) and 18.3 (12.4-24) mm at the ascending aorta level (p  <  0.05). Increased @entity337 was related to increased aortic diameter. No sign of @entity731 was detected in @entity1 with BAV. Deterioration of LV function was seen using MPI, and aortic dilation was related to the severity of @entity337 .

Evaluation of Cardiovascular Changes in XXXX with BAVs.

@entity1 :: ('9606', 'Species') :: ['children'] @entity1004 :: ('MESH:C563733', 'Disease') :: ['carotid intima-media thickness', 'CIMT'] @entity337 :: ('MESH:D001022', 'Disease') :: ['aortic valve insufficiency'] @entity1495 :: ('4318', 'Gene') :: ['matrix metalloproteinase-9'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular risk']
@entity1 :: (9606,Species) :: ['Children']
