We report the results of a study performed in the thoracic surgery department of Hospital General Universitario of Valencia from October 1989 to December 1996. Of the 621 @entity1 diagnosed of @entity2 during this period, 320 underwent the usual surgical excision, 18 were confirmed histologically as @entity5 , indicating an incidence of 5.6% of all @entity2 resected in our department. The symptoms most often reported were recurring infection (44.5%) and @entity662 (33.3%). Only one @entity1 presented @entity4303 . The most common radiologic presentation was solitary pulmonary nodule (50%). The @entity5 was visible by fiberoptic bronchoscopy in 9 cases. Diagnosis was by bronchial biopsy in four cases. Confirmation was by immunohistochemical analysis of the specimen in all cases. Electron microscopy and immunohistochemical techniques using neuroendocrine panmarkers is considered fundamental for differentiating between neuroendocrine @entity5 and typical and atypical @entity5 . Thirteen (72.2%) of the 18 @entity1 studied were diagnosed of typical @entity4303 and 5 (27.8%) of @entity4303 . Neuroendocrine marking showed neurospecific enolase in 15 @entity1 and chromogranin positivity in 10.

[Bronchial XXXX : a prospective study].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'bronchial carcinoid tumors', 'carcinoid tumors', 'neoplasms'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer', 'pulmonary neoplasms'] @entity4303 :: ('MESH:D002276', 'Disease') :: ['carcinoid syndrome', 'atypical carcinoids', 'carcinoids']
@entity5 :: (MESH:D009369,Disease) :: ['carcinoid tumors']
