The majority of double-blind placebo-controlled trials have shown that 30-40% of @entity309 ( @entity309 ) @entity1 can improve substantially by using an elimination diet to identify foods that precipitate symptoms and the avoiding of these foods. Some such @entity1 have discontinued drug treatment and remained well for 12 years or more. Prior to the elimination diet, most @entity1 had not recognised diet as a trigger for their symptoms, because the offending foods were eaten daily. (Foods eaten infrequently can also provoke sensitivity, resulting in @entity625 .) Additionally, many @entity309 @entity1 are sensitive to several foods, making a rigorous elimination diet essential for diagnosis. The pattern of response to an elimination diet (30-40% of @entity309 @entity1 respond well; response occurs within 10-21 days; benefits are maintained if offending foods are avoided) is markedly different from the pattern of response to a fast (almost all @entity309 @entity1 respond well; response occurs within 3-5 days; benefits are lost rapidly when a normal diet is resumed). Clearly fasting and the elimination diet have different therapeutic mechanisms. The effect of fasting may be mediated by the absence of dietary fat, leading to a shortage of pro-inflammatory @entity2918 and @entity4443 . The mechanism by which food sensitivity is involved in @entity309 remains unknown, but weight loss is definitely not responsible for the improvement seen on an elimination diet. Some evidence implicates the gut flora. Food-sensitive @entity309 @entity1 may also show changes in immune parameters during an elimination diet, but no consistent universal change has yet been found.

Food sensitivity and XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity625 :: ('MESH:D001168', 'Disease') :: ['episodic arthritis'] @entity4443 :: ('MESH:D015289', 'Chemical') :: ['leukotrienes'] @entity2918 :: ('MESH:D011453', 'Chemical') :: ['prostaglandins'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA']
@entity309 :: (MESH:D001172,Disease) :: ['rheumatoid arthritis']
