UNASSIGNED: This was an observational study comparing @entity794 transmission with no decolonization of medical @entity1 to required decolonization of all @entity794 carriers during two consecutive periods: baseline with no decolonization of medical @entity1 (16 months), and universal @entity794 carrier decolonization (13 months). The setting was a one-hospital, 156 bed facility with 9,200 annual admissions. Regression models were used to compare rates of @entity794 acquisition. Chi-square was used to compare event frequencies. We used rates of @entity794 clinical disease as an outcome monitor of the program. Analysis was done on 15,666 @entity1 who had admission and discharge tests. 27.9% of inpatient days occupied by a @entity794 positive @entity1 (colonized @entity1 days) received decolonization while hospitalized during the baseline period (this 27.9% represented those who had planned surgery) compared to 76.0% during the intervention period (p<0.0001). The rate of @entity794 transmission was 97 events (1.0%) for 9,415 admissions (2.0 Transmission Events/1,000 @entity1 -days) during baseline and 87 (1.4%) for 6,251 admissions (2.7 Transmission Events/1,000 @entity1 -days) during intervention (p=0.04; RR=0.74, 95% CI = 0.55-1.00). The @entity794 nosocomial clinical disease rate was 5.9 infections/10,000 @entity1 days in the baseline and 7.2 infections/10,000 @entity1 days for the intervention period (Rate ratio = 0.82 (95% confidence interval: 0.46 - 1.45); p=0.49). Decolonization of @entity794 @entity1 does not add benefit when contact precautions are used for @entity1 colonized with @entity794 in acute (hospital) care.

The Non-Impact of Decolonization as an Adjunctive Measure to Contact Precautions for the Control of Methicillin-Resistant XXXX Transmission in Acute Care.

@entity1 :: ('9606', 'Species') :: ['patient', 'patients'] @entity794 :: ('1280', 'Species') :: ['MRSA']
@entity794 :: (1280,Species) :: ['Staphylococcus aureus']
