OBJECTIVE: Predictors for early mortality after isolated pulmonary resection have been identified and clear guidelines regarding fitness for surgery have been produced. However, the additional risk of en-bloc chest wall resection has not been extensively studied. AIM: We analyzed our total experience of combined chest wall and lung resection for @entity1149 ( @entity1149 ) to identify additional risk factors for early @entity5 related mortality. @entity1 AND METHODS: A retrospective review of 41 consecutive @entity1 , with median age of 69 (range 37-84) years, operated by a single surgeon over a 4-year period. Univariate analysis was performed to assess the relationship of selected preoperative and operative variables on mortality within 2 months from surgery. RESULTS: Low preoperative body mass index, age over 75 years, and preoperative FEV(1) of less than 70% of predicted were associated with a significantly increased 60-day mortality. In those @entity1 with any of these risk factors 60-day mortality was 47% (8 of 17). In those with none of the above there was no mortality (of 24 @entity1 ) (P=0.0004). DISCUSSION: En-bloc pulmonary and chest wall resection for @entity1149 should be avoided in the elderly, those with limited respiratory reserve or significant @entity353 . These factors render the @entity1 highly susceptible to chest complications leading to increased mortality.

En-bloc chest wall and lung resection for XXXX . Predictors of 60-day non-cancer related mortality.

@entity5 :: ('MESH:D009369', 'Disease') :: ['non-tumour'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small-cell lung cancer'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss']
@entity1149 :: (MESH:D002289,Disease) :: ['non-small cell lung cancer']
