AIM: To analyze the anti-inflammatory and analgetic properties of the topical comfrey, preparations Kytta-Salbe f, Kytta-Plasma f and Kytta-Balsam f applied to @entity2981 , @entity6475 and @entity158 of the muscles and joints. METHOD: A prospective open multicentric observational study complying with paragraph 67(6) of the AMG and involving 162 general practitioners. During the two-week period of observation, the @entity1 received an average of one to three applications of the comfrey preparation per day. All 492 questionnaires were evaluated. Efficacy and tolerability were assessed by both physician and @entity1 . RESULTS: @entity158 at rest and on movement, as also tenderness, improved in the overall observation group by an average of 45-47%. The duration of morning joint @entity2693 decreased from 20 minutes initially to 3 minutes. During the course of treatment with comfrey, more than two-thirds of the @entity1 were able to reduce or even discontinue their intake of non-steroidal anti-inflammatory drugs and other specific concomitant medication. In most of the cases, both effectiveness and tolerability were assessed to be excellent or good. CONCLUSION: The results of the study confirm the effectiveness and tolerability of the topical comfrey preparation investigated in the treatment of @entity2981 , @entity6475 as well as @entity158 affecting muscles and joints.

[Therapeutic characteristance and tolerance of topical comfrey preparations. Results of an observational study of XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity6475 :: ('MESH:D013180', 'Disease') :: ['sprains and distortions'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'painful conditions'] @entity2981 :: ('MESH:D003288', 'Disease') :: ['bruises'] @entity2693 :: ('MESH:C566112', 'Disease') :: ['stiffness']
@entity1 :: (9606,Species) :: ['patients']
