The aim of this study was to describe the prevalence at birth of two @entity1625 ( @entity1625 ), omphalocela and @entity6675 and to identify possible etiologic factors. The @entity1625 came from 265,858 consecutive births of known ouome registered in the registry of @entity600 of Strasbourg for the period 1979 to 1998. Request information on the @entity1 , the pregnancy, the parents and the family was obtained for cases and for controls. Hundred five cases with @entity1625 were analysed, 55.2 % were omphalocele and 44.8 % were @entity6675 . The mean prevalence rate for omphalocele was 2.18 per 10,000 and for @entity6675 1.76 per 10,000. Associated @entity600 were found in 74.1 % of omphalocele compared with 53.2 % of @entity6675 ; 29.3 % of fetuses with omphalocele had an abnormal karyotype, 44,8 % had a recognizable syndrome, association or an unspecified @entity600 pattern; 51.0 % of fetuses with @entity6675 had additional @entity600 that were not of chromosomal origin, but 1 case. Antenatal ultrasound examination was able to detect 39 (67.2 %) cases of omphaloceles and 27 (57.4 %) cases of @entity6675 . In 30 (51.7 %) cases of omphalocele and in 7 (14.9 %) cases of @entity6675 parents opted for termination of pregnancy. The overall survival rate was 14 (24.1 %) for omphalocele and 30 (63.8 %) for @entity6675 . Weight, length and head circumference at birth of @entity1 with @entity1625 were less than those of controls. The weight of placenta of @entity1 with @entity1625 was not different from the weight of placenta of controls. @entity6675 was associated with significantly younger maternal age than omphalocele. Pregnancies with @entity1625 were more often complicated by threatened abortion, @entity2906 and @entity2978 . Mothers of @entity1 with @entity1625 took more often medication during pregnancy than mothers of controls.

Risk factors in congenital XXXX (omphalocele and gastroschisi): a study in a series of 265,858 consecutive births.

@entity1 :: ('9606', 'Species') :: ['children', 'infants', 'child'] @entity1625 :: ('MESH:D004828', 'Disease') :: ['abdominal wall defects', 'AWD'] @entity2978 :: ('MESH:D006831', 'Disease') :: ['polyhydramnios'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations', 'congenital malformations', 'malformation'] @entity6675 :: ('MESH:D020139', 'Disease') :: ['Gastroschisis', 'gastroschisis'] @entity2906 :: ('MESH:D016104', 'Disease') :: ['oligohydramnios']
@entity1625 :: (MESH:D004828,Disease) :: ['abdominal wall defects']
