INTRODUCTION: In @entity6 the heart rate variability is decreased because of the @entity4148 and parallel with this phenomenon the overnight blood pressure fall is lost. Presumably this change in the hemodynamic parameters is connected with the fact that the @entity65 in type 1 @entity6 @entity1 are 2-4 times more frequent than in healthy @entity1 . The volatility, as a new factor, is the dispersion of the proportion of the blood pressure values following each other. It exactly reflects the 24-hour blood pressure fluctuation, while the dipper/non-dipper determination differentiates only between the daytime and night-time average blood pressure values. The volatility follows the changes of the measured values in accordance to the frequency of the measurements during the whole day. AIM: Our aim was to compare the blood pressure variability of type 1 @entity6 @entity1 ( @entity3918 ) and healthy controls (C). @entity1 AND METHODS: The authors examined 43 @entity6 @entity1 from our outpatient clinic and 45 healthy @entity1 . The blood pressures were measured with Meditech ABPM 02 monitor on workdays. The measurements started in the mornings. The frequency of the measurements was 20 minutes during the day and 50 minutes at night-time. The authors took the history of all the @entity1 and detailed laboratory results. The @entity1 also had ophthalmology examination, ECG and echocardiography tests. RESULTS: During the Ambulatory Blood Pressure Monitoring we found that the systolic volatility of blood pressure values was significantly lower in @entity3918 compared to C @entity1 . Systolic volatility: 0.133 +/- 0.011 vs. 0.175 +/- 0.014 p < 0.026. Comparing only the normotonic C and @entity3918 group systolic volatility of blood pressure values were significantly lower in @entity3918 . Systolic volatility: 0.128 +/- 0.016 vs. 0.177 +/- 0.021 p < 0.036. CONCLUSION: It is an important new finding that in type 1 @entity6 @entity1 the volatility--a new parameter for determining blood pressure variability--is lower than in the healthy control group. At normotension state other parameters describing the blood pressure variability (like diurnal index or standard deviation) could not show this change.

[Blood pressure volatility--a new parameter for determining blood pressure variability in type-1 XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS', 'people'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic', 'diabetes'] @entity4148 :: ('MESH:D001342', 'Disease') :: ['autonomic neuropathy'] @entity3918 :: ('MESH:D009223', 'Disease') :: ['DM'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular complications']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes mellitus']
