BACKGROUND AND PURPOSE: Use of oral contraceptives has increased, and there is uncertainty about the @entity64 risk associated with their use. Our aim was to investigate this issue. METHODS: Using case-control techniques, we identified consecutive @entity1 with @entity385 from 4 Melbourne hospitals. All @entity1 were between 15 and 55 years of age and had no prior @entity64 . Neighborhood-based control subjects were individually age-matched (+/-5 years) and geographically matched to subject cases. A questionnaire administered to @entity1 elicited information about prior exposure to various potential risk factors, including the @entity1697 ( @entity1697 ). RESULTS: We included 234 cases and 234 controls (mean age, 42 years). Compared with noncurrent use, current use of the @entity1697 , in doses of <or=50 microg @entity172 , was not associated with an increased risk of @entity385 (odds ratio [OR] 1.76; 95% CI, 0.86 to 3.61; P=0.124). Factors associated with an increased risk of @entity385 were a history of @entity101 (OR, 2.18; 95% CI, 1.22 to 3.91), transient @entity63 attack (OR, 8.17; 95% CI, 1.69 to 39.6), previous @entity583 (OR, 5.64; 95% CI, 1.04 to 30.61), and @entity6 (OR, 5.42; 95% CI, 1.42 to 20.75); family history of @entity64 (OR, 2.22; 95% CI, 1.12 to 4.43); and smoking >20 cigarettes per day (OR, 3.68; 95% CI, 1.22 to 11.09). CONCLUSIONS: There was no evidence for an association between @entity385 and use of the @entity1697 in low doses (<or=50 microg @entity172 ) in young Australian @entity1 . Other modifiable risk factors such as @entity101 , @entity6 , and smoking are important.

Risk of XXXX among users of the @entity1697 : The Melbourne Risk Factor Study (MERFS) Group.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients'] @entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1697 :: ('MESH:D009062', 'Disease') :: ['OCP', 'oral contraceptive pill'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['ischemic stroke']
