UNASSIGNED: There is controversial data regarding the relationship between @entity414 (UA) and @entity453 and @entity65 . Despite the deleterious effects of @entity5052 on endothelial function, the effect of UA on @entity741 has not been previously studied. We aimed to investigate the relationship between UA and @entity741 that was identified using @entity452 stress echocardiography (DSE). In this retrospective study, the laboratory and DSE reports of 548 @entity1 were reviewed. The @entity1 were divided into two groups based on the presence of @entity63 and further subdivided into three groups according to the extent of @entity63 (none, @entity63 in 1-3 segments, @entity63 in >3 segments). Serum UA levels were compared. Determinants of @entity63 were assessed using a regression model. UA was increased in @entity1 with @entity63 and was correlated with the number of @entity63 segments (p  <  0.001). A cutoff value of UA  >  5  mg/dl had 63.9  % sensitivity, 62.0  % specificity, 42.5  % positive predictive value ( @entity2286 ), and 79.6  % negative predictive value for @entity63 . When the positive DSE exams were further sorted according to the UA cutoff, the @entity2286 of DSE increased from 80.2 to 94.0  %. @entity414 (odds ratio 1.51; 95  % CI 1.14-1.99), @entity6 , HDL and glomerular filtration rate were found to be independent determinants of @entity741 in DSE. Increased UA is associated with both the presence and extent of DSE-identified @entity741 . A UA cutoff may be a good method to improve the @entity2286 of DSE.

Effect of serum @entity414 on the positive predictive value of XXXX stress echocardiography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['dobutamine'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia', 'ischemic'] @entity2286 :: ('12211', 'Species') :: ['PPV'] @entity741 :: ('MESH:D017202', 'Disease') :: ['myocardial ischemia'] @entity5052 :: ('MESH:D033461', 'Disease') :: ['hyperuricemia'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular events'] @entity414 :: ('MESH:D014527', 'Chemical') :: ['Uric acid', 'uric acid']
@entity452 :: (MESH:D004280,Chemical) :: ['dobutamine']
