BACKGROUND: @entity82 is a pivotal event in @entity1188 repair and progressive remodeling after @entity583 ( @entity583 ). Biomarkers may be used to monitor @entity82 , and therefore we evaluated the predictive value of galectin-3 and sST2 for @entity299 after @entity583 . METHODS: Plasma galectin-3 and sST2 were measured in @entity1 admitted with primary percutaneous coronary intervention (PCI) for @entity583 , at baseline and at 4months. @entity1002 ( @entity1002 ) and @entity1188 size were measured after 4months with cardiac MRI (CMR). RESULTS: In total, 247 @entity1 had blood samples and CMR data available (mean age 57.7  11.6years; 79.8% male). Increased baseline galectin-3 (>= 17.8ng/mL) identified @entity1 with lower @entity1002 (50.3% (  9.1) vs. non-elevated galectin-3 55.0% (  8.0); P<0.001), and larger @entity1188 size (13.8g. (  12.9) vs. 8.6g. (  8.7); P=0.002) after 4months. Elevated sST2 (>= 35.0ng/mL) did not predict decreased @entity1002 or larger @entity1188 size. Furthermore we showed that at baseline, galectin-3 was an independent predictor for @entity1002 (b=-0.18; P=0.005) and @entity1188 size (b=0.18; P=0.004). We repeated the analyses using median values of galectin-3 (13.4ng/mL) and sST2 (30.3ng/mL) as a cut point, and this validated our results. CONCLUSION: The @entity82 biomarker galectin-3, but not sST2, taken immediately after @entity583 , predicts @entity1002 and @entity1188 size after 4months. We hypothesize that galectin-3 may play a role in the pathophysiology of @entity299 after @entity583 .

Galectin-3 and sST2 in prediction of left ventricular ejection fraction after XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis', 'Fibrosis'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac remodeling'] @entity583 :: ('MESH:D009203', 'Disease') :: ['acute MI', 'myocardial infarction', 'MI'] @entity1002 :: ('MESH:D018487', 'Disease') :: ['Left ventricular ejection fraction', 'LVEF']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
