BACKGROUND: @entity0 is an important cause of @entity204 among @entity1 . One way of classifying different forms of @entity0 is by molecular features, usually in terms of the four subtypes: luminal A, luminal B, @entity1722 -enriched, and triple negative. OBJECTIVES: This study aimed to investigate the association between molecular subtypes and survival among @entity0 @entity1 treated with radiotherapy. MATERIALS AND METHODS: A retrospective cohort study was conducted. The subjects were 272 @entity0 @entity1 who had received treatment in the radiotherapy unit at Srinagarind Hospital, Thailand, between 1 January, 1999, and 31 May, 2009. The end of the study was 1 June, 2014. Overall survival was defined as the time elapsing between initial registration at the radiotherapy unit and @entity204 or the end of the study. Survival curves were estimated by the Kaplan-Meier method, and a multivariate analysis was performed using Cox's proportional hazard regression model. RESULTS: The @entity1 mean age was 47.5  10.4 at the time of diagnosis. Of the 272 @entity1 , 146 (53.7%) were classified as luminal A, 12 (4.4%) as luminal B, 30 (11.0%) as @entity1722 -enriched, and 84 (30.9%) as triple negative. The overall survival rates at 1, 3 and 5 years were 87.1%, 68.4% and 59.2%, respectively. According to molecular subtypes, @entity1722 -enriched @entity1 had the lowest 5-year survival rate (30.0 %, 95%CI: 15.02-46.55). The median follow-up time was 8.37 years. In the Cox model analysis a higher risk of @entity204 was found for @entity1 with @entity1722 -enriched (HRadj=3.34, 95%CI:1.96-5.67), triple negative (HRadj=2.17, 95%CI: 1.44-3.27), and stage IIlB (HRadj=2.20, 95%CI: 1.16-4.17) @entity5 . CONCLUSIONS: The worst survival rates were among @entity1 classified as @entity1722 -enriched, triple negative and at stage IIIB. Early detection and an advanced treatment modality are needed to help these @entity1 .

Survival time and molecular subtypes of XXXX after radiotherapy in Thailand.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity0 :: ('MESH:D001943', 'Disease') :: ['Breast cancer', 'breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity1722 :: ('2064', 'Gene') :: ['HER2']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
