BACKGROUND: In this study, we aimed to investigate the effectiveness of @entity7292 (SN) versus @entity803 in pleurodesis among @entity1 with @entity3483 ( @entity3483 ). METHODS: In this prospective randomized clinical trial, @entity1 with unilateral @entity3483 candidate for pleurodesis were enrolled. The @entity1 randomly allocated in two groups for receiving 20 mL 0.5% SN or 2.5 g @entity803 diluted in 30 cc normal saline and 0.1% @entity3303 , through the chest tube. @entity1 were followed-up immediately (during 24 h) and 1-month after the procedure for evaluating recurrence of the @entity1143 using chest radiograph. They were clinically evaluated for @entity662 and/or @entity1353 and @entity221 using a questionnaire that completed by the surgeon. The results were compared with two groups. RESULTS: During this trial, 50 @entity1 with @entity3483 candidate for pleurodesis were selected and randomized into two interventional groups (25 @entity1 in each group). Immediate and late recurrence of @entity1143 after pleurodesis were similar in two groups (P > 0.05). All @entity1 in @entity803 group had @entity221 and @entity662 , but in SN group @entity221 and @entity662 were reported in 3 (12%) and 12 (48%) of @entity1 , respectively (P < 0.05). CONCLUSION: SN is at least as effective as @entity803 for @entity3483 treatment. In addition, its side effects were lower than @entity803 . Other advantages of SN are its low cost, availability, and safety. For more accurate results, it is recommended to design further trials with larger sample size and with lower doses of both SN and @entity803 .

@entity7292 versus XXXX in pleurodesis for @entity3483 ; a prospective randomized trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1143 :: ('MESH:D010996', 'Disease') :: ['pleural effusion'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity7292 :: ('MESH:D012835', 'Chemical') :: ['silver nitrate'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity3483 :: ('MESH:D016066', 'Disease') :: ['MPE', 'malignant pleural effusion'] @entity803 :: ('MESH:D013752', 'Chemical') :: ['tetracycline'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever']
@entity803 :: (MESH:D013752,Chemical) :: ['tetracycline']
