BACKGROUND: @entity67 ( @entity67 ) increases morbidity and mortality. The RECOVER RIGHT study evaluated the safety and efficacy of a novel percutaneous right ventricular assist device, the Impella @entity6391 (Abiomed, Danvers, MA), in a prospective, multicenter trial. METHODS: Thirty @entity1 with @entity67 refractory to medical treatment received the Impella @entity6391 device at 15 United States institutions. The study population included 2 cohorts: 18 @entity1 with @entity67 after left ventricular assist device (LVAD) implantation (Cohort A) and 12 @entity1 with @entity67 after cardiotomy or @entity583 (Cohort B). The primary end point was survival to 30 days or hospital discharge (whichever was longer). Major secondary end points included indices of safety and efficacy. RESULTS: The @entity1 (77% male) were a mean age of 59    15 years, 53% had @entity6 , 88.5% had a history of @entity712 , and 37.5% had @entity8 . @entity1 were on an average of 3.2 inotropes/pressors. Device delivery was achieved in all but 1 @entity1 . Hemodynamics improved immediately after @entity6391 support, with an increase in cardiac index from 1.8    0.2 to 3.3    0.23 liters/min/m(2) (p < 0.001) and a decrease in central venous pressure from 19.2    4 to 12.6    1 mm Hg (p < 0.001). @entity1 were supported for an average of 3.0    1.5 days (range, 0.5-7.8 days). The overall survival at 30 days was 73.3%. All @entity1 discharged were alive at 180 days. CONCLUSIONS: In @entity1 with life-threatening @entity67 , the novel percutaneous Impella @entity6391 device was safe, easy to deploy, and reliably resulted in immediate hemodynamic benefit. These data support its probable benefit in this gravely ill @entity1 population.

Benefits of a novel percutaneous ventricular assist device for @entity712 : The prospective RECOVER RIGHT study of the Impella XXXX device.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal dysfunction'] @entity712 :: ('MESH:D006333', 'Disease') :: ['congestive heart failure'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity6391 :: ('MESH:D012174', 'Disease') :: ['RP', 'initiation of Impella RP'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity67 :: ('MESH:D018754', 'Disease') :: ['Right ventricular failure', 'RVF']
@entity6391 :: (MESH:D012174,Disease) :: ['RP']
