Primary @entity5 of female urethra is rare and represents about 0.02% of all @entity5 found in @entity1 and the majority of them are @entity957 . Diagnosis is difficult due to the fact that the disease has usually reached advanced stage. We report our experience with two @entity1 with @entity420 . METHODS: We describe clinical-pathological findings and treatment carried out in two @entity1 with @entity420 . We review the literature focusing on the origin of these @entity5 and available treatment options. RESULTS: After diagnosis, radical surgery was performed in both @entity1 . Despite this, one @entity1 died of local progression. The other @entity1 is still alive and free of recurrence. CONCLUSIONS: @entity420 of the female urethra is a rare @entity5 of difficult diagnosis. Surgery is the only curative treatment. Chemotherapy (CT ) and radiotherapy (RT ) must be used in @entity1 in whom surgery is not possible, although there is no consensus on the best therapeutic approach. Prognosis tends to be poor due to delay in diagnosis.

XXXX : report of two cases and bibliographic review.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'neoplasias', 'cancer', 'tumors'] @entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinomas'] @entity420 :: ('MESH:D000230', 'Disease') :: ['Adenocarcinoma', 'urethral adenocarcinoma']
@entity420 :: (MESH:D000230,Disease) :: ['Female urethra adenocarcinoma']
