OBJECTIVES: To present an overview of current knowledge regarding the epidemiology, pathophysiology, and evaluation of @entity322 ( @entity322 ) with a focus on the problem of the @entity2182 . METHODS: The most recent data on the epidemiology of @entity322 are presented. The literature on the pathophysiology of urinary urge incontinence (UUI) is reviewed, and key concepts related to @entity1 evaluation are summarized. RESULTS: The prevalence of @entity322 depends on the population being surveyed. The @entity2182 constitutes a substantial percentage of the overall problem, ranging from > 50% of incontinent @entity1 to only 10% to 15% of incontinent younger @entity1 . Few data are available on the incidence of the disorder or on racial/ethnic trends. @entity2182 or urge incontinence is called @entity427 when a neurologic cause is known and detrusor instability when there is no @entity16 . Although the pathophysiology of idiopathic instability is not well understood, some evidence suggests that this condition may result from subclinical @entity16 or primary smooth @entity121 . Most @entity1 with UUI can be adequately evaluated with a history, physical examination, determination of postvoid residual volume, and urinalysis. When @entity16 or other complicating factors are present, or if initial treatment fails, sophisticated urodynamic testing is appropriate. CONCLUSIONS: @entity322 is prevalent in all strata of the population, although it affects @entity1 and the elderly disproportionately. With the exception of cases in which a @entity16 can be demonstrated, the etiology of UUI remains elusive. A thorough history, physical examination, determination of postvoid residual, and urinalysis will be adequate to classify and treat the majority of @entity1 .

Epidemiology, pathophysiology, and evaluation of XXXX and @entity2182 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity322 :: ('MESH:D014549', 'Disease') :: ['urinary incontinence', 'UI', 'Urinary incontinence'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic lesion', 'neurologic abnormality', 'neurologic disease'] @entity2182 :: ('MESH:D053201', 'Disease') :: ['Overactive bladder', 'overactive bladder'] @entity427 :: ('MESH:D012021', 'Disease') :: ['detrusor hyperreflexia'] @entity121 :: ('MESH:D009135', 'Disease') :: ['muscle disease']
@entity322 :: (MESH:D014549,Disease) :: ['urinary incontinence']
