BACKGROUND: @entity6018 is a rare disease associated with a favorable short-term prognosis. Longer follow-up documenting a persistence of symptoms and a high rate of recurrence after debulking surgery along with an uncertain natural history prompt a re-evaluation of prior treatment recommendations. No prior long-term clinical study of these @entity1 is available. METHODS: The experience with five cases of @entity6018 , four females and one male, are reviewed. All of these @entity1 were treated with cytoreductive surgery with peritonectomy procedures and heated intraoperative intraperitoneal chemotherapy. CT, pathology and current status were investigated in order to learn more about the natural history of this disease. RESULTS: All @entity1 were symptomatic from abdominal distention and three of the four complained of severe @entity158 . Female @entity1 complained of long periods of recurrent abdominal and pelvic @entity158 poorly managed by oral analgesics. In one @entity1 prolonged conservative management over ten years resulted in transition to an invasive process with extensive lymph nodal metastases. Her prognosis for long-term survival is guarded because of @entity2615 extension into the chest. Disease control of both @entity843 and @entity158 in the abdomen and pelvis was achieved in all five @entity1 treated with cytoreductive surgery plus intraperitoneal chemotherapy. CONCLUSIONS: @entity6018 should no longer be referred to as "benign" @entity6018 . An aggressive approach with complete disease eradication is the correct goal of treatment. From our experience, cytoreductive surgery to remove all visible @entity5 and intraperitoneal chemotherapy to control microscopic @entity66 will help @entity1 with peritoneal @entity6018 to remain symptom- and disease-free over an extended time period with a single surgical intervention. Disease eradication may prevent the transition to an @entity146 process.

XXXX : a case series.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['residual disease'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive and fatal disease'] @entity6018 :: ('MESH:D018261', 'Disease') :: ['cystic mesothelioma', 'Cystic peritoneal mesothelioma', 'cystic peritoneal mesothelioma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity2615 :: ('MESH:D008654', 'Disease') :: ['mesothelioma'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity6018 :: (MESH:D018261,Disease) :: ['Peritoneal cystic mesothelioma']
