BACKGROUND: D-dimer quantitative test is mainly used to rule out the presence of @entity1031 ( @entity1031 ). Whether very high D-dimer (100 times above the cutoff point) can exclusively indicate the presence of TED should be known. METHODS: D-dimer was detected by a quantitative immunoturbidimetric assay. The normal value is 0.2-0.7  mg/L fibrinogen equivalent units (FEUs). During the year of 2009, 1,053 D-dimer tests were performed. We analyzed the results of these @entity1 to find out the causes of very high D-dimer. RESULTS: The mean value of D-dimer in the 1,053 tests was 8.56  mg/L FEU, ranging from <0.2  mg/L to 563.2  mg/L FEU. Of them, 28 samples from 21 @entity1 had very high D-dimer value: >50  mg/L FEU. Of the 21 @entity1 , 9 (43%) had TED, 1 had suspected TED, but not proved by computed tomographic (CT) angiogram, 3 had massive gastrointestinal or other site @entity548 , 3 @entity1 had @entity1167 with samples taken immediately after recovery from cardiopulmonary resuscitation (CPR), 2 had @entity295 with @entity5642 ( @entity5642 ), 1 had postpartum @entity2102 ( @entity2102 ) syndrome with @entity3126 and @entity177 , 1 had multiple @entity130 , and 1 received thrombolytic therapy. CONCLUSION: Although TED was the most frequently seen disorder in @entity1 with very high D-dimer value, very high D-dimer was not necessary exclusively the marker of TED. Other disorders such as @entity548 , status post CPR, @entity295 with @entity5642 , multiple @entity130 , @entity9660 and @entity2102 can also have very high D-dimer.

Can very high level of D-dimer exclusively predict the presence of XXXX ?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding', 'massive bleeding'] @entity3126 :: ('MESH:D011654', 'Disease') :: ['acute pulmonary edema'] @entity2102 :: ('MESH:D017359', 'Disease') :: ['HELLP', 'hemolysis, elevated liver enzymes, low platelets', 'HELLP syndrome'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity5642 :: ('MESH:D004211', 'Disease') :: ['DIC', 'disseminated intravascular coagulation'] @entity9660 :: ('MESH:C567640', 'Disease') :: ['hyperfibrinolysis'] @entity1031 :: ('MESH:D013923', 'Disease') :: ['TEDs', 'thromboembolic diseases'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['cardiac arrest'] @entity130 :: ('MESH:D014947', 'Disease') :: ['traumatic injuries', 'traumatic injury']
@entity1031 :: (MESH:D013923,Disease) :: ['thromboembolic diseases']
