Data concerning the incidence of latent @entity259 (LTC) in populations with @entity4759 are scarce. Despite the introduction of @entity1496 @entity5651 prophylaxis in the early sixties, @entity1496 supply is still insufficient in Austria and @entity5651 remains endemic. This is the first detailed study dealing with epidemiological features of LTC at autopsy in Austria. A total of 118 thyroid glands were included in the study. The glands were serially sectioned at 2- to 3-mm intervals, embedded in @entity982 and histologically examined for the presence of LTC. In addition, the incidence and severity of @entity1669 ( @entity1669 ) were evaluated. Ten thyroids were found to contain LTC (8.6%). All were of the papillary type. The mean @entity5 dimension was 4.9 mm +/- 3.2, the smallest lesion measuring 1 mm. Only the largest @entity5 slightly exceeded the extent of a @entity7172 and measured 10.5 mm. @entity66 was present in three cases (30%). The prevalence of latent @entity3557 (LPTC) was 6.6% (n = 4) in females and 10.5% (n = 6) in males. The mean age of the subjects with LPTC was 67.7 +/- 14.4 yr, range 37 to 77 yr. Goitrous thyroids were seen in 33 cases (28%): One gland was diffusely enlarged and 32 (27.1%) enlarged glands were @entity8170 . The overall prevalence of @entity1669 was 30.5% (n = 36) and the only type of @entity1374 observed was focal @entity1669 (FLT). There was no correlation between the presence of LPTC and @entity5651 , the presence of FLT and the subjects' age and sex. The incidence of LPTC in Austria is similar to that in nongoitrous regions. The adult population at large seems to be uniformly exposed to factors involved in the initiation and early growth of @entity3557 ( @entity3557 ). This suggests that the levels of @entity1496 intake only play a minor role in the early phase of the carcinogenesis of @entity3557 , but may be of some importance in the progression of LPTC to clinically evident @entity3557 .

Latent XXXX in Austria: a systematic autopsy study.

@entity3557 :: ('MESH:C536915', 'Disease') :: ['papillary thyroid carcinoma', 'PTC'] @entity8170 :: ('MESH:D006044', 'Disease') :: ['nodular goiters'] @entity1496 :: ('MESH:D007455', 'Chemical') :: ['iodine'] @entity66 :: ('MESH:D004194', 'Disease') :: ['Multifocal disease'] @entity1669 :: ('MESH:D013967', 'Disease') :: ['LT', 'lymphocytic thyroiditis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity982 :: ('MESH:D010232', 'Chemical') :: ['paraffin'] @entity5651 :: ('MESH:D006042', 'Disease') :: ['goiter'] @entity7172 :: ('MESH:C563277', 'Disease') :: ['microcarcinoma'] @entity259 :: ('MESH:D013964', 'Disease') :: ['thyroid carcinoma'] @entity4759 :: ('MESH:D006043', 'Disease') :: ['endemic goiter'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroiditis']
@entity259 :: (MESH:D013964,Disease) :: ['carcinoma of the thyroid']
