The purpose of this study was to investigate the effectiveness and detect side effects of centered, overlapped endovascular gamma irradiation after angioplasty of de novo femoropopliteal stenoses. Thirty @entity1 (age 65.3+/-9.2 years) with @entity432 were prospectively enrolled to receive endovascular gamma irradiation (192- @entity3201 , 14 Gy centered at 2 mm vessel wall) immediately after percutaneous transluminal angioplasty (PTA) of femoropopliteal stenoses. Irradiation overlapped dilatation by 1-2 cm at each end. Follow-up involved angiography after 12 months; duplex sonography; and interviews before and after PTA and at 1, 6, and 12 months follow-up. @entity865 and centered endovascular irradiation were performed successfully in all @entity1 . Three @entity1031 occurred during irradiation. Angiographic and clinical follow-up was possible in 28 @entity1 . The angiographic degree of @entity850 was 73.8%+/-16.3% before and 3.6%+/-23.5% after PTA and was 3.5%+/-43.7% at the 1-year follow-up. @entity256 (>50%) of the @entity75 developed in three @entity1 (10.7%) and edge stenoses (>30%) in nine @entity1 (32.1%). An @entity439 of the irradiated segment in one @entity1 was treated by stenting. The rate of retreatment was 17.9%. The vessel diameter after endovascular gamma irradiation and PTA of femoropopliteal stenoses remained stable. @entity256 , induction of edge stenoses, and @entity439 were reasons for reinterventions.

Endovascular gamma irradiation for the prevention XXXX after angioplasty of femoropopliteal de novo stenoses.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity75 :: ('MESH:D001927', 'Disease') :: ['target lesion'] @entity256 :: ('MESH:D023903', 'Disease') :: ['Restenosis'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysm'] @entity1031 :: ('MESH:D013923', 'Disease') :: ['thromboembolic complications'] @entity865 :: ('CHEBI:61432', 'Chemical') :: ['PTA'] @entity432 :: ('MESH:D001157', 'Disease') :: ['arterial occlusive disease'] @entity3201 :: ('MESH:D007495', 'Chemical') :: ['iridium'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis']
@entity256 :: (MESH:D023903,Disease) :: ['restenosis']
