The occurrence of @entity8 ( @entity8 ) was sought retrospectively in 36 consecutive @entity1 with @entity2631 , seen in a single rheumatology unit, over a 12-year period. The diagnosis @entity8 was considered when at least one of the following findings was present: systolic blood pressure greater than or equal to 95 mmH, @entity644 greater than or equal to 0.5 gr/24 hr., and @entity1011 clearance less than or equal to 50 ml/min.: at least one of these features was found in 16 @entity1 . @entity101 was the most frequent feature of @entity8 (15 out of 16 @entity1 ). Two forms of @entity101 were observed. Firstly: malignant @entity101 occurring early in the course of @entity8 , seen in 5 @entity1 , 4 of whom rapidly developed @entity177 . Secondly: a moderate @entity101 , seen in 10 @entity1 with a more favourable outcome, occurring on average 53 months after the diagnosis of @entity2631 was made. @entity644 was only seen in association with malignant @entity101 . @entity8 occurred in 7 @entity1 . Of the 36 @entity1 with @entity2631 , 14 died; 10 of these 14 @entity1 had @entity8 . Thus the death rate in @entity1 with @entity8 was very high, whereas only 4 out of 20 died in the group without @entity8 .

XXXX , value of clinical markers.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity644 :: ('MESH:D011507', 'Disease') :: ['Proteinuria', 'proteinuria'] @entity8 :: ('MESH:D007674', 'Disease') :: ['Renal impairment', 'renal scleroderma', 'RSc'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'Hypertension'] @entity2631 :: ('MESH:D012594', 'Disease') :: ['scleroderma'] @entity177 :: ('MESH:D051437', 'Disease') :: ['terminal renal insufficiency'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity8 :: (MESH:D007674,Disease) :: ['Renal scleroderma']
