AIMS: To identify the Candida species that cause @entity363 and determine their antifungal susceptibility patterns. STUDY DESIGN: This was a cross-sectional study. PLACE AND DURATION OF STUDY: The study was conducted at the antenatal clinic of Mbarara Regional Referral Hospital in Mbarara Municipality, between December 2012 and February 2013. METHODS: High vaginal swabs from 456 pregnant @entity1 were subjected to microscopy and culture on Sabouraud Dextrose Agar. Candida isolates were identified by the germ tube and Analytical profile index (API(  ) Candida) tests. Susceptibility to @entity2380 , @entity2059 and @entity18111 was determined by the Etest strips and for @entity1449 and @entity8701 by the disc diffusion method on Mueller Hinton agar supplemented with 2%w/v @entity413 and 0.5 g/ml @entity6693 dye. RESULTS: Of the 456 High vaginal swabs cultured, 207 grew Candida species. Species distribution was as follows: @entity5132 (78.95%), @entity7408 (14.35%), C. krusei (3.35%), @entity9841 (1.44%), C. famata (0.96%), @entity7409 (0.48%) and @entity19323 (0.48%). Resistance to @entity8701 was only observed in 0.61% of @entity5132 . Resistance to @entity1449 was observed in 50%, 36.67% and 0.61% of C. famata, @entity7408 and @entity5132 respectively. C. krusei showed a high resistance of 71.43% to @entity2380 . @entity7408 , C. krusei, C. famata and @entity19323 exhibited 100% resistance to @entity2059 . Resistance to @entity18111 of less than 11% was exhibited by only @entity5132 and @entity7408 . CONCLUSION: @entity5132 was susceptible to most antifungal agents tested except @entity2059 and @entity18111 . All isolates were susceptible to @entity8701 except less than 1% of @entity5132 . Non-albicans demonstrated resistance to some drugs especially @entity2059 . We recommend use of @entity8701 for empirical management of @entity363 among pregnant @entity1 .

Antifungal Susceptibility Patterns of Vulvovaginal Candida species among XXXX Attending Antenatal Clinic at Mbarara Regional Referral Hospital, South Western Uganda.

@entity1 :: ('9606', 'Species') :: ['women'] @entity9841 :: ('5482', 'Species') :: ['C. tropicalis'] @entity363 :: ('MESH:D002181', 'Disease') :: ['vulvovaginal candidiasis'] @entity1449 :: ('MESH:D003022', 'Chemical') :: ['clotrimazole'] @entity2380 :: ('MESH:D015725', 'Chemical') :: ['fluconazole'] @entity7408 :: ('5478', 'Species') :: ['C. glabrata'] @entity8701 :: ('MESH:D009761', 'Chemical') :: ['Nystatin', 'nystatin'] @entity6693 :: ('MESH:D008751', 'Chemical') :: ['methylene blue'] @entity7409 :: ('5480', 'Species') :: ['C. parapsilosis'] @entity5132 :: ('5476', 'Species') :: ['C.albicans', 'Candida albicans', 'C. albicans'] @entity18111 :: ('MESH:D065819', 'Chemical') :: ['voriconazole'] @entity19323 :: ('36911', 'Species') :: ['C. lusitaniae'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity2059 :: ('MESH:D017964', 'Chemical') :: ['itraconazole']
@entity1 :: (9606,Species) :: ['Women']
