OBJECTIVE: Localized @entity263 is a common disease for which minimally invasive treatment methods are being explored. Perineal prostatectomy, as a historical open procedure, is modified to incorporate contemporary surgical ideas. There is relatively little in the literature regarding modern adaptations of perineal prostatectomy. This method of anatomic radical perineal prostatectomy has been developed to accomplish a minimally invasive method of achieving goals of disease control and preservation of genito-urinary functions. METHODS: Prospective outcome data is accumulated on 508 consecutive radical perineal prostatectomies by a single surgeon. Pathologic stage and PSA detectability are measures of @entity5 control. Pad use and ability to complete intercourse measure urinary and sexual function. General complications and other outcome measures are evaluated. RESULTS: Freedom from PSA detectability by pathologic stage is 96.3%, 79.4%, and 69.4% for organ confined, specimen confined and margin positive in the absence of seminal vesical invasion with an average 4 years follow up (3-114 months). Margins are positive in 18% of cases. The average @entity5 size is 9.4g and 36% of cases have extracapsular invasion. By the first, third, sixth months and one year, 38%, 65%, 88% and 96% are free of pad use and report being dry. While over 80% of nerve-spared @entity1 enjoy the return of spontaneous erectile function, the @entity1 with bilateral nerve preservation note earlier and more complete return of function. There are no cardiopulmonary complications or @entity204 . Transfusions occurred in 1%, none in the past 400 cases. Average total hospital charges are USD 4889.00 in 1999 and 2000. @entity3832 , anastomotic strictures and fecal urgency/stress flatus occur 2%, 2% and 2-4%, respectively. CONCLUSIONS: This method of prostatectomy is able to achieve complete @entity5 resection while preserving urinary and sexual function as well as laparoscopic or retropubic prostatectomy. The simplicity and minimally invasive nature of this procedure contribute to a short recovery and low overall cost of therapy. The anatomic radical perineal prostatectomy is a cost-efficient, outcome effective minimally invasive method of treating @entity1 with @entity263 .

Radical perineal prostatectomy: cost efficient, outcome effective, minimally invasive XXXX management.

@entity1 :: ('9606', 'Species') :: ['men', 'patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['localized prostate cancer', 'prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity3832 :: ('MESH:D014525', 'Disease') :: ['Anterior urethral strictures'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
