BACKGROUND: Clinical staging of @entity420 (GEJ) determines the curative treatment regimen containing either neoadjuvant chemotherapy or chemoradiotherapy followed by either gastrectomy or esophagectomy. The value of current diagnostic tools is a matter of debate. METHODS: A prospective database (2003-2013) was used to identify 266 consecutive @entity1 with @entity420 of the GEJ in order to evaluate the accuracy of endoscopic ultrasound (EUS) and computed tomography (CT) regarding @entity5 localization according to Siewert, nodal status and its consequences on treatment strategy. RESULTS: Overall accuracy in determining @entity5 localization was 73% for endoscopy/EUS and 61% for CT (p  =  0.018). With endoscopy/EUS, the accuracy was 97%, 66% and 75%  respectively for type I, II and III. With CT this was respectively 69%, 57% and 80%. The overall accuracy for determining N-status (N0/N+) per @entity1 was 75% for EUS and 71% for CT. Accuracy for determining a positive nodal station in @entity1 without neoadjuvant therapy was 77% for EUS and 71% for CT (p  =  0.001). Accuracy for detecting positive upper mediastinal nodes was 80-92%, whereas for peritumoral and abdominal nodes this was 50-80% in both EUS and CT. In 8/266 @entity1 (3%) the type of surgery changed due to intraoperative findings. A radical resection was performed in 233 @entity1 (88%). CONCLUSIONS: Despite the suboptimal accuracy of determining @entity5 localization with EUS and CT, in only a small number of @entity1 an intraoperative change of surgical treatment was needed. EUS is superior to CT in determining nodal status and @entity5 localization in GEJ @entity5 .

Staging of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma of the gastroesophageal junction', 'adenocarcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors']
@entity420 :: (MESH:D000230,Disease) :: ['adenocarcinoma of the gastroesophageal junction']
