BACKGROUND: @entity99 have been described in @entity8404 ( @entity8404 ) in isolated case reports, and most of these have been reported to be @entity157 . OBJECTIVES: The aim of the present study was to determine the frequency, imaging, and histopathologic characteristics of @entity99 in @entity1 with @entity8404 . METHODS: Available abdominal imaging of @entity1 with @entity8404 was retrospectively reviewed to note the presence of any focal @entity409 , its location, and imaging characteristics. Other findings including signs of @entity101 , portal lymph nodes, and splenic and @entity8 were also noted. Findings were correlated with pathology in available cases and with clinical follow-up. RESULTS: Of 55 @entity1 with clinically and/or genetically confirmed @entity8404 followed in the liver clinic, 39 (19 @entity1 , 20 @entity1 ; mean age 8.9 years) with imaging available on picture archival and communication system were included in the study. Focal @entity99 were seen in 12 of the 39 (30%) @entity1 , solitary in 11 and multiple in 1. Ten of these @entity1 had a large nodule adjacent to the right portal vein. The median diameter of the lesions was 8.1 cm (range 5.6-9.8 cm). Magnetic resonance imaging features and pathology in available cases were suggestive of a regenerative nodule. a-fetoprotein levels were normal in all except 1 @entity1 who had mild elevation. CONCLUSIONS: Combining our series and previous case reports, the presence of a large nodule adjacent to the right portal vein appears to be a common finding in @entity8404 . The typical location, normal a-fetoprotein levels, and magnetic resonance imaging features with vessels coursing through the lesion can reliably differentiate this benign nodule from @entity157 .

Solitary Hepatic Nodule Adjacent to the Right Portal Vein: A Common Finding of XXXX ?

@entity1 :: ('9606', 'Species') :: ['child', 'children', 'girls', 'boys'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal abnormalities'] @entity101 :: ('MESH:D006973', 'Disease') :: ['portal hypertension'] @entity8404 :: ('MESH:D016738', 'Disease') :: ['Alagille syndrome', 'ALGS'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver lesion'] @entity157 :: ('MESH:D006528', 'Disease') :: ['hepatocellular carcinoma'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic lesions', 'Hepatic lesions']
@entity8404 :: (MESH:D016738,Disease) :: ['Alagille Syndrome']
