The origin of the isolated @entity1887 is unknown in most cases. An observation of a group of over 100 @entity1 with @entity1887 and coexisting @entity792 suggests that @entity792 could be a frequent cause of @entity177 , similarly as in @entity5343 . We studied 176 @entity1 with idiopathic isolated @entity1887 . The methods included clinical examination and measurements of pituitary, adrenal, thyroid and gonadal hormones in all the cases. Since @entity1669 has been the most frequent finding in @entity5343 we have also chosen thyroid autoantibodies as markers of an autoimmune process in our material. Anti-peroxidase, anti-microsomal and anti-thyroglobulin autoantibodies were determined in 151 @entity1 . In 111 out of 151 @entity1 (73%) coexisting @entity792 and/or presence of thyroid autoantibodies were detected. The most frequent @entity792 associated with @entity1887 were @entity1375 , @entity1378 (mainly in the past) and @entity11157 . Thyroid autoantibodies, especially antiperoxidase autoantibodies, were present in 106 @entity1 . Thus, coexistence of isolated @entity1887 with some @entity792 in 73% of the @entity1 under study suggests that @entity792 is the most frequent cause of the idiopathic form of this disease.

XXXX as the most frequent cause of @entity1887 : report of 111 cases.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1375 :: ('MESH:D007037', 'Disease') :: ['primary hypothyroidism'] @entity11157 :: ('MESH:D016649', 'Disease') :: ['premature ovarian failure'] @entity1669 :: ('MESH:D013967', 'Disease') :: ['thyroid autoimmunity'] @entity1887 :: ('MESH:D000309', 'Disease') :: ['secondary adrenal insufficiency'] @entity1378 :: ('MESH:D006980', 'Disease') :: ['hyperthyroidism'] @entity177 :: ('MESH:D051437', 'Disease') :: ['idiopathic secondary failure'] @entity5343 :: ('MESH:D000224', 'Disease') :: ["Addison's disease"] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmunity', 'autoimmune abnormalities', 'autoimmune disorders', 'autoimmune diseases']
@entity792 :: (MESH:D001327,Disease) :: ['Autoimmunity']
