PURPOSE: To determine whether residual spherical and cylindrical errors could be corrected postoperatively using spatially profiled UV light irradiation in @entity1 with @entity3467 undergoing @entity231 surgery and implantation of a light adjustable, @entity1346 intraocular lens (LAL). DESIGN: We conducted a prospective, nonrandomized clinical trial. The LALs were implanted in eyes with axial lengths <22.20 mm and were treated with a spatial intensity profile delivered by a digital light delivery device to induce a targeted spherical and cylindrical refractive change postoperatively. Once the desired correction was achieved, the LAL was treated again to lock-in the lens power. @entity1 : We studied 15 eyes of 15 @entity1 with @entity3467 . METHODS: The manifest refraction, uncorrected visual acuity (UCVA), and best spectacle-corrected visual acuity (BCVA) were determined with follow-up time of 12 months to determine the achieved refractive corrections and their stability. MAIN OUTCOME MEASURES: We measured UCVA, BCVA, achieved versus targeted refractive outcome, and refractive stability with a follow-up time of 12 months. RESULTS: Of 15 eyes, 14 (93%) achieved    0.5 diopters (D), and 10 (67%) were within    0.25 D of the targeted refractive adjustment up to 12 months postoperative follow-up. Only 1 treated eye showed a change of 0.38 D in manifest spherical equivalent refraction, the remaining 14 eyes showed <0.25 D change between 1 month post lock-in, and at the 3-, 6-, and 12-month postoperative visits. CONCLUSIONS: The light-adjustable lens is a promising technology with the potential to reduce the rate of postoperative refractive surprises up to 2 D of spherical and cylindrical errors after @entity231 surgery. @entity86 were successfully corrected with precision and significant improvement in UCVA and without compromising BCVA using the light-adjustable intraocular lens technology. The data demonstrate the stability of the achieved refractive change after the adjustment and lock-in procedures.

Combined correction of XXXX and astigmatism using the light adjustable intraocular lens.

@entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract'] @entity3467 :: ('MESH:D006956', 'Disease') :: ['axial hyperopia'] @entity1346 :: ('MESH:D012828', 'Chemical') :: ['silicone'] @entity86 :: ('MESH:D019106', 'Disease') :: ['Postoperative refractive errors']
@entity3467 :: (MESH:D006956,Disease) :: ['axial hyperopia']
