AIM: @entity170 is a worldwide health problem and @entity174 from @entity170 are among the major causes of disability, with a great impact on the national health budgets. The aim of our study was to analyze the efficacy of FRAX algorithm and phalanger ultrasound to predict the risk of @entity3604 , in order to identify a high risk population to examine with a second level diagnostic analysis. METHODS: The study population was composed of 1208 premenopausal, perimenopausal, and postmenopausal @entity1 , between 40 and 81 years. For each @entity1 phalangeal QUS was performed and FRAX index was calculated. The FRAX index was evaluated according to standard plots available on web (http://www.shed.ac.uk/FRAX/index.htm). RESULTS: Analysing the correlation between @entity1 age and phalanger bone ultrasound values we know that all parameter decrease with increasing of age. We found a significant difference between FRAX index and the ultrasound parameters (P<0.05) to predict a major @entity3604 , we did not find differences between age and ultrasound parameters. Furthermore, we show that after correction per age of the @entity1 the ultrasound parameters lose their significant correlation with major @entity3604 . Finally, FRAX index showed a good AUC and in our population and a 10-year probability over 9.4% of major @entity3604 had a good specificity (88%) and sensitivity (83%) to predict @entity3604 . CONCLUSION: Our data suggest that FRAX index alone could be used to address high risk @entity1 to more invasive tests but we need more data about ultrasound parameters.

Identification of @entity1 with high XXXX risk: analysis of FRAX and phalangeal ultrasonography in a female population in North-East Italy.

@entity3604 :: ('MESH:D058866', 'Disease') :: ['osteoporotic fracture', 'osteoporotic fractures'] @entity1 :: ('9606', 'Species') :: ['women', 'woman'] @entity170 :: ('MESH:D010024', 'Disease') :: ['Osteoporosis', 'osteoporosis'] @entity174 :: ('MESH:D050723', 'Disease') :: ['bone fractures']
@entity170 :: (MESH:D010024,Disease) :: ['osteoporosis']
