Although @entity1222 ( @entity1222 ) is a familiar entity to most radiologists and to pediatric radiologists in particular, it is but one of a group of disorders caused by the overproduction of histiocytes, a subtype of white blood cells. Other @entity66 in this category are @entity10630 ( @entity10630 ), @entity6725 ( @entity6725 ), @entity9312 ( @entity9312 ), and @entity9058 ( @entity9058 ). This review describes the classification system, clinical manifestations, and pathophysiology of each disease, with particular attention to differential radiographic findings, including typical locations of involvement and varying appearances at radiography, computed tomography, magnetic resonance imaging, ultrasonography, and nuclear medicine imaging. Although @entity1222 has a wide variety of manifestations and appearances, classic imaging findings include vertebra plana, skull lesions with a beveled edge, the "floating tooth" sign, bizarre @entity358 , and an absent posterior pituitary bright spot with infundibular thickening. The classic imaging findings of @entity10630 are a perirenal rind of soft tissue and @entity79 . @entity9312 has more nonspecific imaging findings, including lymphadenopathy (most commonly cervical) and @entity1504 . Imaging findings in @entity9058 are broad, with the most common abnormalities being @entity828 , cerebral @entity393 , and periventricular @entity62 . @entity6725 can manifest at imaging, but radiology does not play a major role in diagnosis. Familiarity with these disorders and their associated imaging findings facilitates correct and timely diagnosis. Imaging also features prominently in the assessment of treatment response.

More than just XXXX : a radiologic review of histiocytic disorders.

@entity9312 :: ('MESH:D015618', 'Disease') :: ['RDD', 'Rosai-Dorfman disease'] @entity66 :: ('MESH:D004194', 'Disease') :: ['less familiar diseases'] @entity6725 :: ('MESH:D014972', 'Disease') :: ['JXG', 'juvenile xanthogranuloma'] @entity9058 :: ('MESH:D051359', 'Disease') :: ['HLH', 'hemophagocytic lymphohistiocytosis'] @entity1222 :: ('MESH:D006646', 'Disease') :: ['Langerhans cell histiocytosis', 'LCH'] @entity10630 :: ('MESH:D031249', 'Disease') :: ['Erdheim-Chester disease', 'ECD'] @entity1504 :: ('MESH:D002561', 'Disease') :: ['intracranial lesions'] @entity828 :: ('MESH:C535727', 'Disease') :: ['hepatosplenomegaly'] @entity79 :: ('MESH:D001847', 'Disease') :: ['patchy long bone osteosclerosis'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung cysts'] @entity62 :: ('MESH:D056784', 'Disease') :: ['white matter abnormalities'] @entity393 :: ('MESH:D034381', 'Disease') :: ['volume loss']
@entity1222 :: (MESH:D006646,Disease) :: ['Langerhans cell histiocytosis']
