Efforts to examine the process and risk of developing @entity615 have relied generally upon retrospective study of individuals with already established @entity158 . In an alternative approach to understanding the clinical course and evolution of @entity1643 , a cohort of 76 @entity1 experiencing their first episode of @entity615 was assessed prospectively at 2, 6 and 12 months following @entity158 onset. Standard measures of @entity158 (Descriptor Differential Scale: DDS), disability (Sickness Impact Profile: SIP), and distress (Beck Depression Inventory: BDI) were employed to classify the sample into five groups: Resolved, @entity158 Only, Disability/Distress Only, @entity158 and Mild Disability/Distress, and Clinical Range. At both 6 and 12 months post @entity158 onset, most (78%, 72% respectively) of the sample continued to experience @entity158 . Many also experienced marked disability at 6 months (26%) and 12 months (14%). At 12 months, no @entity1 had worsened relative to the 2-month baseline. Doubly multivariate analyses of variance (MANOVAs) were employed to compare baseline groups ( @entity158 Only, @entity158 and Mild Disability/Distress, Clinical Range) on the DDS, SIP, and BDI across time. The group by time interaction from 2 through 12 months was reliable, with greatest change occurring in the Clinical Range group in disability and distress; interestingly, the decrease in @entity158 was comparable among all groups. Follow-up tests across measures demonstrated greater change in the early (2-6-month) interval and relative stability in the later (6-12-month) interval. Comparison of those classified as 'improvers' with those who did not improve from 2 to 12 months showed similar findings. The clinical course of first onset @entity615 may be prolonged for many @entity1 , and involves a continuum of related disability and distress. Individuals at risk for marked symptoms 1 year after an initial episode of @entity615 can be identified early, and prompt treatment might reduce the risk of @entity158 chronicity.

One-year follow-up of first onset XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'men'] @entity615 :: ('MESH:D001416', 'Disease') :: ['chronic back pain', 'back pain'] @entity1643 :: ('MESH:D017116', 'Disease') :: ['low back disorders'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain']
@entity1643 :: (MESH:D017116,Disease) :: ['low back pain']
