BACKGROUND AND PURPOSE: The severity of @entity7025 is generally scaled with conventional angiography and nuclear medicine. Arterial spin-labeling MR imaging is now acknowledged for the noninvasive quantification of cerebral blood flow. This study aimed to analyze CBF modifications with statistical parametric mapping of arterial spin-labeling MR imaging in @entity1 undergoing an operation for @entity7025 . MATERIALS AND METHODS: We included 15 @entity1 treated by indirect cerebral revascularization with multiple burr-holes between 2011 and 2013. Arterial spin-labeling MR imaging and T1 sequences were then analyzed under SPM8, according to the general linear model, before and after the operation (3 and 12 months). Voxel-based analysis was performed at the group level, comparing all diseased hemispheres with all normal hemispheres and, at the individual level, comparing each @entity1 with a control group. RESULTS: Group analysis showed statistically significant preoperative hypoperfusion in the MCA territory in the Moyamoya hemispheres and a significant increase of cerebral perfusion in the same territory after revascularization (P < .05 family-wise error-corrected). Before the operation, individual analysis showed significant hypoperfusion for each @entity1 co-localized with the angiographic defect on DSA. All except 1 @entity1 had improvement of CBF after revascularization, correlated with their clinical status. CONCLUSIONS: SPM analysis of arterial spin-labeling MR imaging offers a noninvasive evaluation of preoperative cerebral hemodynamic impairment and an objective assessment of postoperative improvement in @entity1 with @entity7025 .

Cerebral Blood Flow Improvement after Indirect Revascularization for XXXX : A Statistical Analysis of Arterial Spin-Labeling MRI.

@entity1 :: ('9606', 'Species') :: ['children', 'patient'] @entity7025 :: ('MESH:D009072', 'Disease') :: ['Moyamoya disease']
@entity7025 :: (MESH:D009072,Disease) :: ['Pediatric Moyamoya Disease']
