@entity1204 is the leading cause of malignancy of the female genital tract. Prognosis of this @entity5 , which has implications on @entity1 management, is determined by evaluation of the stage of disease, architectural grade, nuclear grade, @entity3 , and peritoneal cytology. These parameters have inherent subjectivity and, therefore, the search for an objective reliable parameter to determine prognosis is required. DNA ploidy is under investigation as an objective and reproducible prognostic parameter. This study will evaluate the role of DNA ploidy and its relationship to the traditional parameters as predictors of prognosis in @entity1 with @entity1204 . Fifty-eight @entity1 were evaluated by two observers for architectural grade according to the International Federation of Gynecology and Obstetrics classification, nuclear grade, and depth of @entity3 . DNA ploidy was evaluated using flow cytometer (FACscan, Becton Dickinson, San Jose, CA). Histologic parameters were than compared with DNA ploidy. Survival data were obtained from the @entity5 registry. Results of @entity1 survival were compared with histologic parameters and DNA ploidy. Higher nuclear grade and @entity2007 correlated with poor survival rate (P <.05). Higher nuclear grade correlated with @entity2007 . The survival of @entity1 with architectural grade 2 (moderately differentiated) @entity1204 is poorer if the @entity5 is aneuploid as compared with diploid as determined by flow cytometry. In conclusion, @entity2007 and nuclear grade correlates with poor @entity1 survival. The poorer survival rates with aneuploid architectural grade 2 @entity1204 may have an impact on clinical management.

Role of DNA ploidy analysis in XXXX .

@entity1204 :: ('MESH:D016889', 'Disease') :: ['endometrial carcinoma', 'endometrial adenocarcinoma', 'Endometrial adenocarcinoma'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2007 :: ('MESH:D000782', 'Disease') :: ['aneuploidy'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['myometrial invasion']
@entity1204 :: (MESH:D016889,Disease) :: ['endometrial adenocarcinoma']
