@entity79 ( @entity79 ) is a DXA-based tool that assesses bone texture and reflects microarchitecture. It has been shown to independently predict the risk of @entity3604 in the elderly. In this study, we investigated the determinants of @entity79 in adolescents. INTRODUCTION: @entity79 is a gray-level textural measurement derived from lumbar spine DXA images. It appears to be an index of bone microarchitecture that provides skeletal information additional to the standard @entity1555 measurement and clinical risk factors. Our objectives were to characterize the relationship between @entity79 and both age and pubertal stages and identify other predictors in adolescents. METHODS: We assessed @entity79 by reanalyzing spine DXA scan images obtained from 170 @entity1 and 168 @entity1 , age range 10-17  years, gathered at study entry and at 1  year, using @entity79 software. The results are from post hoc analyses obtained using data gathered from a prospective randomized @entity560 trial. Predictors of @entity79 were assessed using t test or Pearson's correlation and adjusted using regression analyses, as applicable. RESULTS: The mean age of the study population was 13.2        2.1  years, similar between @entity1 and @entity1 . Age, height, weight, sun exposure, spine BMC and @entity1555 , body BMC and @entity1555 , and lean and fat mass are all significantly correlated with @entity79 at baseline (r   =   0.20-0.75, p   <   0.035). Correlations mostly noted in late-pubertal stages. However, after adjustment for BMC, age remained an independent predictor only in @entity1 . CONCLUSIONS: In univariate exploratory analyses, age and pubertal stages were determinants of @entity79 in adolescents. Studies to investigate predictors of @entity79 and to investigate its value as a prognostic tool of @entity79 in the pediatric population are needed.

Predictors of trabecular bone score in school XXXX .

@entity3604 :: ('MESH:D058866', 'Disease') :: ['osteoporotic fracture'] @entity1 :: ('9606', 'Species') :: ['girls', 'boys'] @entity79 :: ('MESH:D001847', 'Disease') :: ['Trabecular bone score', 'bone fragility', 'TBS'] @entity1555 :: ('MESH:D020388', 'Disease') :: ['BMD'] @entity560 :: ('MESH:D014807', 'Chemical') :: ['vitamin D']
@entity1 :: (9606,Species) :: ['children']
