BACKGROUND: Perihilar @entity201 has one of the poorest prognoses of all @entity5 . However, mortality and morbidity rates after surgical resection are 0-15% and 14-66%, respectively. Additionally, the 5-year overall survival rates are reported at 22-40%. These findings indicate that only selected @entity1 achieve satisfactory beneficial effects from operative treatment. This retrospective study sought to investigate preoperatively available prognostic factors and establish a new preoperative staging system to predict survival after major hepatectomy of @entity201 . @entity1 AND METHODS: We evaluated 121 consecutive @entity1 who underwent operative exploration for @entity201 . RESULTS: Univariate and multivariate analysis using the identified preoperative factors revealed that 4 factors (platelet-lymphocyte ratio [PLR]  >  150, serum @entity1851 [ @entity1851 ] levels > 0.5  mg/dL, albumin levels < 3.5  g/dL, and @entity787 [ @entity787 ] levels > 7.0  ng/mL) were independent prognostic factors of postoperative survival. These 4 preoperative factors were allocated 1 point each. The total score was defined as the Preoperative Prognostic Score (PPS). @entity1 with a PPS of 0, 1, 2, or 3/4 had a 5-year survival of 84.3%, 51.3%, 46.4%, and 0%, respectively. There were also differences in the 5-year survival according to the PPS (0 vs 1 [P  =  .013] and 2 vs 3/4 [P  <  .001]). @entity1 with a total PPS of 3/4 had a dismal prognosis, with a median survival of 11.3  months. CONCLUSION: A new preoperative scoring system using PLR, serum @entity1851 , albumin, and @entity787 levels could predict postoperative survival resection of @entity201 .

A new prognostic scoring system using factors available preoperatively to predict survival after operative resection of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers'] @entity787 :: ('1084', 'Gene') :: ['CEA', 'carcinoembryonic antigen'] @entity201 :: ('MESH:D018281', 'Disease') :: ['perihilar cholangiocarcinoma', 'cholangiocarcinoma'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein', 'CRP']
@entity201 :: (MESH:D018281,Disease) :: ['perihilar cholangiocarcinoma']
