OBJECTIVE: To investigate the relationship between awareness of @entity2414 and psychological well-being in a nonclinically @entity308 sample of @entity1 with mild to moderate @entity195 ( @entity195 ). METHODS: Study @entity1 (N  = 104) enrolled through Columbia University Medical Center and the University of Pennsylvania completed clinical and cognitive assessments. @entity1 were rated with regard to their degree of @entity2414 and completed questionnaires relating to their psychological well-being, including mood and quality of life (QOL). Mediating models were used to establish the relationship between awareness, @entity308 , and QOL and to examine potential mediators of awareness and @entity308 , including @entity458 , objective @entity2414 , and negative self-ratings. RESULTS: There was a direct association between @entity2414 and @entity308 mood but not awareness and QOL. However, there was an indirect association between awareness and QOL through @entity308 . Neither @entity458 , @entity2414 , nor negative self-ratings mediated the relationship between awareness and @entity308 . CONCLUSION: Awareness is associated with @entity308 mood in nonclinically @entity308 @entity1 with mild to moderate @entity195 . However, @entity308 mood does not appear to reflect the direct psychological reaction to awareness of @entity2414 . Moreover, awareness has only an indirect association with QOL via @entity308 mood. These results suggest that preserved awareness does not have a direct negative impact on overall psychological well-being in @entity195 .

Examining the Pathways between Self-Awareness and Well-Being in Mild to  Moderate XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'Participants'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressed', 'depression'] @entity458 :: ('MESH:D020018', 'Disease') :: ['psychological distress'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', 'Alzheimer disease'] @entity2414 :: ('MESH:D008569', 'Disease') :: ['memory loss', 'memory deficits', 'awareness of memory deficits']
@entity195 :: (MESH:D000544,Disease) :: ['Alzheimer Disease']
