BACKGROUND: @entity130 is common in @entity75 , but the link with @entity409 is unknown. We hypothesized that alterations of cerebral autoregulation are associated with @entity130 in neonates treated with @entity2332 ( @entity2332 ) for @entity75 . METHODS: The cerebral hemoglobin volume index ( @entity28682 ) from near-infrared spectroscopy was used to identify the mean arterial blood pressure (MAP) with optimal autoregulatory vasoreactivity (MAPOPT). We measured associations between MAP relative to MAPOPT and indicators of @entity130 (duration of mechanical respiratory support and administration of inhaled @entity842 (iNO), @entity7604 , or @entity230 ). RESULTS: We identified associations between cerebrovascular autoregulation and @entity130 that were often sex-specific. Greater MAP deviation above MAPOPT was associated with shorter duration of intubation in @entity1 but longer ventilatory support in @entity1 . Greater MAP deviation below MAPOPT related to longer intensive care stay in @entity1 . @entity7604 was associated with greater MAP deviation below MAPOPT in @entity1 . CONCLUSION: MAP deviation from MAPOPT may relate to @entity130 after @entity75 , and sex may modulate this relationship. Whereas MAP above MAPOPT may protect the brain and lungs in @entity1 , it may be related to @entity130 in @entity1 . Future studies are needed to characterize the role of sex in these associations.Pediatric Research (2017); doi:10.1038/pr.2017.23.

Sex-specific associations between cerebrovascular blood pressure autoregulation and @entity130 in XXXX and @entity2332 .

@entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity1 :: ('9606', 'Species') :: ['boys', 'girls'] @entity28682 :: ('214439', 'Species') :: ['HVx'] @entity75 :: ('MESH:D001927', 'Disease') :: ['neonatal encephalopathy'] @entity130 :: ('MESH:D014947', 'Disease') :: ['cardiopulmonary injury', 'Cardiopulmonary injury'] @entity409 :: ('MESH:D008107', 'Disease') :: ['cerebrovascular dysfunction'] @entity842 :: ('MESH:D009569', 'Chemical') :: ['nitric oxide'] @entity7604 :: ('MESH:D020105', 'Chemical') :: ['milrinone', 'Milrinone'] @entity2332 :: ('MESH:D007035', 'Disease') :: ['TH', 'therapeutic hypothermia']
@entity75 :: (MESH:D001927,Disease) :: ['neonatal encephalopathy']
