BACKGROUND: @entity1 with @entity346 suffer @entity12870 , which leads to an unstable visual perception and therefore impaired visual acuity. The aim of this study was to use real-time computer-based visual feedback to compensate for the destabilizing slow phase eye movements. METHODS: The @entity1 were sitting in front of a computer screen with the head fixed on a chin rest. The eye movements were recorded by an eye tracking system (EyeSeeCam  ). We tested the visual acuity with a fixed Landolt C (static) and during real-time feedback driven condition (dynamic) in gaze straight ahead and (20  ) sideward gaze. In the dynamic condition, the Landolt C moved according to the slow phase eye velocity of the @entity346 . The Shapiro-Wilk test was used to test for normal distribution and one-way ANOVA for comparison. RESULTS: Ten @entity1 with @entity346 were included in the study. Median age was 76  years and the median duration of symptoms was 6.3  years (SD +/- 3.1y). The mean slow phase velocity was moderate during gaze straight ahead (1.44  /s, SD +/- 1.18  /s) and increased significantly in sideward gaze (mean left 3.36  /s; right 3.58  /s). In gaze straight ahead, we found no difference between the static and feedback driven condition. In sideward gaze, visual acuity improved in five out of ten subjects during the feedback-driven condition (p   =   0.043). CONCLUSIONS: This study provides proof of concept that non-invasive real-time computer-based visual feedback compensates for the SPV in DBN. Therefore, real-time visual feedback may be a promising aid for @entity1 suffering @entity12870 and impaired text reading on screen. Recent technological advances in the area of virtual reality displays might soon render this approach feasible in fully mobile settings.

Real-time computer-based visual feedback improves visual acuity in XXXX - a pilot study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity12870 :: ('MESH:D055191', 'Disease') :: ['from oscillopsia'] @entity346 :: ('MESH:D009759', 'Disease') :: ['downbeat nystagmus syndrome', 'downbeat nystagmus']
@entity346 :: (MESH:D009759,Disease) :: ['downbeat nystagmus']
