OBJECTIVES: The effects of the use of the stapler or hand-sewn method in oesophagogastric @entity254 on postoperative morbidity, mortality and quality of life after oesophagectomy remain controversial. The purpose of his study was to compare clinical outcomes of hand-sewn and stapler techniques in oesophagogastric @entity254 after oesophagectomy for @entity189 . METHODS: We performed a prospective randomized controlled trial on 478 @entity1 treated for oesophageal tumour between February 2009 and December 2011. @entity1 were randomly assigned to two treatment groups with 237 @entity1 in the hand-sewn group and 241 @entity1 in the circular stapler group (http://www.chictr.org: ChiCTR-TRC-13004428). RESULTS: The mean follow-up time was 18 months. The mean operating time of the stapled group and the hand-sewn group were 193 and 226 min, respectively (P < 0.001). Seventeen clinical and radiological leakages occurred in the hand-sewn group compared with 7 in the stapler group (P = 0.033). In the stapler group hospital mortality occurred in 10 @entity1 (4.3%) and in the hand-sewn group in 9 @entity1 (3.9%) (P = 0.837). Anastomotic strictures were noted in 31 @entity1 from the stapler group (14.2%) and in 16 @entity1 from the hand-sewn group (7.5%) (P = 0.027). CONCLUSIONS: Using the circular stapler method in oesophagogastric anastomoses had a lower anastomotic leakage rate and shorter operating time compared with the hand-sewn method. However, the circular stapler method was associated with a significantly increased risk of anastomotic strictures.

Comparison of outcomes following end-to-end hand-sewn and mechanical oesophagogastric @entity254 after oesophagectomy for XXXX : a prospective randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity189 :: ('MESH:D002277', 'Disease') :: ['oesophageal carcinoma']
@entity189 :: (MESH:D002277,Disease) :: ['carcinoma']
