PURPOSE: To evaluate the Ex-PRESS miniature implant (Model R 50) placed under @entity5692 compared with standard trabeculectomy. METHODS: In this retrospective comparative series of 100 eyes, we compared 50 eyes in 49 @entity1 treated with the Ex-PRESS miniature @entity726 implant under a scleral flap with 50 matched control eyes in 47 @entity1 treated with trabeculectomy. Success was defined as intraocular pressure (IOP) > or =5 mm Hg and < or =21 mm Hg, with or without @entity726 medications, without further @entity726 surgery or removal of implant. Early @entity86 was defined as IOP <5 mm Hg during the first postoperative week. RESULTS: The average follow-up was 10.8 months (range 3.5 to 18) for the Ex-PRESS group and 11.2 months (range 3 to 15) for the trabeculectomy group. Although the mean IOP was significantly higher in the early postoperative period in the Ex-PRESS group compared with the trabeculectomy group, the reduction of IOP was similar in both groups after 3 months. The number of @entity86 medications in both groups was not significantly different. Kaplan-Meier survival curve analysis showed no significant difference in success between the 2 groups (P=0.594). Early @entity86 and @entity1143 were significantly more frequent after trabeculectomy compared with Ex-PRESS implant under scleral flap (P<0.001). CONCLUSIONS: The Ex-PRESS implant under a scleral flap had similar IOP-lowering efficacy with a lower rate of @entity8814 compared with trabeculectomy.

Comparison of trabeculectomy with Ex-PRESS miniature XXXX device implanted under scleral flap.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1143 :: ('MESH:D010996', 'Disease') :: ['choroidal effusion'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity8814 :: ('MESH:D015814', 'Disease') :: ['early hypotony'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative hypotony', 'postoperative glaucoma'] @entity5692 :: ('MESH:D015422', 'Disease') :: ['partial-thickness scleral flap']
@entity726 :: (MESH:D005901,Disease) :: ['glaucoma']
