PURPOSE: To study the safety and long-term efficacy of classic viscocanalostomy in @entity1 with @entity1538 ( @entity1538 ) in different populations. METHODS: A total of 726 eyes of 726 @entity1 from Europe or South Africa with primary @entity1538 (POAG) and @entity9998 ( @entity9998 ) were included in this retrospective multicentre study. Complete (qualified) success was defined as an intraocular pressure (IOP) equal to or lower than 21, 18 and 16  mmHg without (with or without) medications, respectively. A failed procedure was defined if IOP was above 21  mmHg, not controllable by laser goniopuncture or medications. RESULTS: The mean IOP before surgery was 42.6      14.2  mmHg for all @entity1 , 29.6      6.6  mmHg for European @entity1 and 48.1      12.9  mmHg for African @entity1 . The follow-up time was 86.2      43.1  months. Mean IOP was 15.4      3.6  mmHg at 5  years, 15.5      4.4  mmHg at 10  years and 16.8      4.2  mmHg at 15  years. The qualified success rate for an IOP of 21, 18 or 16  mmHg or less after 5  years was 92% [95% confidence interval (CI) 0.88-0.96], 70% (95% CI 0.63-0.77) and 43% (95% CI 0.36-0.51) in European @entity1 , and 90% (95% CI 0.87-0.93), 77% (95% CI 0.74-0.81) and 67% (95% CI 0.63-0.72) in African @entity1 , respectively. There was no difference between the success rate for POAG and @entity9998 for an IOP of 21, 18 or 16  mmHg or less at 5  years (p  =  0.64, p  =  0.20, p  =  0.22, respectively). Laser goniopuncture was performed postoperatively on a total of 127 eyes (17.7%), lowering the pressure from 23.1      1.9  mmHg to 15.0      2.2  mmHg. There were no significant complications, in particular, no blebitis or @entity3225 . CONCLUSION: Viscocanalostomy produced a sustained long-term reduction of IOP with a low-risk profile in European and African @entity1 with @entity1538 over 12  years.

Long-term results of up to 12  years of over 700 cases of viscocanalostomy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity9998 :: ('MESH:D017889', 'Disease') :: ['pseudoexfoliative glaucoma', 'PXFG'] @entity3225 :: ('MESH:D009877', 'Disease') :: ['endophthalmitis'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open-angle glaucoma', 'OAG']
@entity1538 :: (MESH:D005902,Disease) :: ['open-angle glaucoma']
