The use of yttria-stabilized @entity10678 nanoparticles as d-SPE clean-up sorbent for a rapid and sensitive liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) method for the determination of post-harvest fungicides ( @entity17284 , @entity9454 , @entity14460 , @entity20880 , @entity52006 , @entity68403 , @entity23412 , @entity36096 , @entity16035 , @entity35934 , @entity21095 , @entity22432 , @entity68404 , @entity18884 , @entity25200 and @entity68405 ) in orange and pear samples has been evaluated and validated. The sample preparation was a modification of the QuEChERS extraction method using yttria-stabilized @entity10678 and multi-walled @entity505 nanotubes (MWCNTs) nanoparticles as the solid phase extraction (d-SPE) clean-up sorbents prior to injecting the ten-fold diluted extracts into the LC system. By using the yttria-stabilized @entity10678 extraction method, more recoveries in the 70-120% range were obtained - thus this method was used for the validation. Quantification was carried out using a matrix-matched calibration curve which was linear in the 1-500  gkg(-1) range for almost all the pesticides studied. The validated limit of quantification was 10  gkg(-1) for most of the studied compounds, except @entity14460 , @entity52006 and @entity25200 . Pesticide recoveries at the 10 and 100  gkg(-1) concentration levels were satisfactory, with values between 77% and 120% and relative standard deviations (RSD) lower than 10% (n=5). The developed method was applied for the determination of selected fungicides in 20 real orange and pear samples. Four different pesticide residues were detected in 10 of these commodities; 20% of the samples contained pesticide residues at a quantifiable level (equal to or above the @entity21211 ) for at least one pesticide residue. The most frequently-detected pesticide residues were: @entity9454 , @entity18884 and @entity23412 -all were below the MRL. The highest concentration found was @entity23412 at 1175  gkg(-1) in a pear sample.

Application of XXXX nanoparticle sorbent for the clean-up step in post-harvest pesticide residue analysis.

@entity68405 :: ('MESH:C426783', 'Chemical') :: ['tolclofos-methyl'] @entity16035 :: ('MESH:D008724', 'Chemical') :: ['methomyl'] @entity17284 :: ('MESH:D012721', 'Chemical') :: ['carbaryl'] @entity52006 :: ('MESH:D005015', 'Chemical') :: ['ethoxyquin'] @entity68403 :: ('MESH:C543009', 'Chemical') :: ['flutriafol'] @entity68404 :: ('MESH:C108337', 'Chemical') :: ['pyrimethanil'] @entity35934 :: ('MESH:C446685', 'Chemical') :: ['myclobutanil'] @entity25200 :: ('MESH:D013875', 'Chemical') :: ['thiophanate-methyl'] @entity22432 :: ('MESH:C045362', 'Chemical') :: ['prochloraz'] @entity21095 :: ('MESH:C014153', 'Chemical') :: ['pirimiphos-methyl'] @entity36096 :: ('MESH:C033148', 'Chemical') :: ['iprodione'] @entity505 :: ('MESH:D002244', 'Chemical') :: ['carbon'] @entity23412 :: ('MESH:C017435', 'Chemical') :: ['imazalil'] @entity14460 :: ('MESH:D002748', 'Chemical') :: ['chlorpropham'] @entity10678 :: ('MESH:C028541', 'Chemical') :: ['zirconium dioxide'] @entity9454 :: ('MESH:C006698', 'Chemical') :: ['carbendazim'] @entity21211 :: ('6895', 'Gene') :: ['LOQs'] @entity20880 :: ('MESH:D004159', 'Chemical') :: ['diphenylamine'] @entity18884 :: ('MESH:D013827', 'Chemical') :: ['thiabendazole']
@entity10678 :: (MESH:C028541,Chemical) :: ['zirconium dioxide']
