UNASSIGNED: When local anesthetics are used, the administration of @entity6948 ( @entity9170 ) can prolong analgesic duration. However, the effect of caudal @entity9170 on high volume/low concentration (HVLC) local anesthetics has not been studied. We investigated the analgesic effect of @entity9170 added to a HVLC of @entity1342 for @entity616 in @entity1 . Eighty @entity1 (the American Society of Anesthesiologists (ASA) status I; age, 1-6 years) undergoing ambulatory orchiopexy were enrolled in the study. @entity1 were randomly assigned to undergo a @entity616 with 1.5   mL/kg of 0.15% @entity1342 and either 1     g/kg of @entity9170 ( @entity9170 group, n=40) or the same amount of saline (Control group, n=40) under general anesthesia. The results showed that the time to first analgesic request was significantly longer in the @entity9170 group than in the control group. The @entity2614 requirement for anesthesia and frequency of emergence agitation (EA) were also significantly lower in the @entity9170 group. There was no difference in adverse events between the two groups. In conclusion, a dose of 1     g/kg of caudal @entity9170 prolonged the first analgesic request time, although the immediate postoperative @entity158 scores were comparable in both groups. Furthermore, caudal @entity9170 significantly reduced the @entity2614 requirement and the frequency of EA.

The Effect of 1     g/kg @entity6948 Combined with High-Volume/Low-Concentration Caudal XXXX in @entity1 Undergoing Ambulatory Orchiopexy.

@entity1 :: ('9606', 'Species') :: ['children', 'Children'] @entity9170 :: ('D003907', 'Chemical') :: ['DEX'] @entity1342 :: ('MESH:C037663', 'Chemical') :: ['ropivacaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity2614 :: ('MESH:C009250', 'Chemical') :: ['sevoflurane'] @entity6948 :: ('MESH:D020927', 'Chemical') :: ['dexmedetomidine'] @entity616 :: ('MESH:D006327', 'Disease') :: ['caudal block']
@entity1342 :: (MESH:C037663,Chemical) :: ['Ropivacaine']
