UNASSIGNED: Accelerated hyperfractionated radiotherapy was performed as treatment for @entity1 with T1 @entity5 , and its utility was evaluated based on treatment outcomes and adverse effects. Fifty-eight @entity1 who had undergone radiotherapy were retrospectively reviewed. Tumor classification was Tis in 4 @entity1 , T1a in 38, and T1b in 16. Histological examination revealed @entity957 in 55 @entity1 . Travel time from home to hospital was 0-1 hour for 24 @entity1 , 1-2 hours for 9, and >2 hours for 25. Laser vaporization was performed prior to radiotherapy in 38 @entity1 , and 19 @entity1 received concurrent chemotherapy with an agent such as S-1. @entity1 were irradiated twice daily using an irradiation container. Most @entity1 received a dose of 1.5 Gy/fraction up to a total of 60 Gy. The median overall treatment time was 30 days, with a median observation period of 59.6 months. A complete response was observed in all @entity1 . The 5-year overall survival, disease-free survival, and local control rates were 97.2%, 93.2%, and 97.8%, respectively. Although grade 3 pharyngeal mucositis was observed in 2 @entity1 , there were no other grade 3 or higher acute adverse events. As late @entity137 , grade 2 @entity4 and grade 1 @entity548 were observed in 1 @entity1 each, but no serious events such as @entity39 or @entity5142 were observed. In conclusion, this treatment method brings excellent outcome and will substantially reduce the treatment duration among @entity1 who need to stay at nearby hotels while undergoing treatment at hospitals in rural areas.

Short treatment time and excellent treatment outcome in accelerated hyperfractionated radiotherapy for T1 XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'men'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity548 :: ('MESH:D006470', 'Disease') :: ['laryngeal hemorrhage'] @entity39 :: ('MESH:D009336', 'Disease') :: ['laryngeal necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['glottic cancer'] @entity4 :: ('MESH:D004487', 'Disease') :: ['laryngeal edema'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity5142 :: ('MESH:D007829', 'Disease') :: ['laryngeal stenosis']
@entity5 :: (MESH:D009369,Disease) :: ['glottic cancer']
