The objective of this study was to determine stable estimates of the incidence, case fatality, and epidemiologic features of @entity5847 , and risk factors for intubation. The authors designed a retrospective cohort combined with a nested case-control study, followed by detailed analysis of cases from two tertiary care institutions. Among 813 cases, the incidence was 2.02 cases/10(5) population per year. Ten recorded deaths constituted a case fatality rate of 1.2% (95% confidence interval [CI]: 0.5% to 1.9%). The eight fully documented deaths indicated no sudden episodes of @entity16839 upper @entity1224 without previous @entity1353 . A detailed review of 51 cases revealed that 18% of @entity1 underwent expeditious intubation. @entity1 managed without initially requiring intubation did not need emergency airway interventions. Only the presence of @entity1353 (noted in 29% of @entity1 ) at the time of admission (P < 0.001) predicted the need for intubation. A low case fatality rate in a conservatively managed cohort and the absence of sudden upper airway catastrophes in @entity1 without @entity1353 suggest that prophylactic intubation and intensive care unit monitoring is not warranted in all @entity1 . An early complaint of @entity1353 may safely discriminate between @entity1 requiring invasive airway management and close observation.

XXXX in a Canadian setting.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity16839 :: ('MESH:D002388', 'Disease') :: ['catastrophic'] @entity5847 :: ('MESH:D004826', 'Disease') :: ['adult epiglottitis'] @entity1224 :: ('MESH:D000402', 'Disease') :: ['airway obstructions']
@entity5847 :: (MESH:D004826,Disease) :: ['Adult epiglottitis']
