BACKGROUND CONTEXT: @entity85 ( @entity85 ) @entity1 may gain @entity922 ( @entity922 ) in one or more of the health-related quality-of-life instruments without surgical intervention. The present study identifies the baseline characteristics of this subset of non-operative @entity1 and proposes predictors of those most likely to benefit. PURPOSE: The study aims to determine the factors that affect likelihood of non-operative @entity1 to reach @entity922 . STUDY DESIGN/SETTING: This is a retrospective review of a prospective, multicenter database. @entity1 SAMPLE: The study includes non-operative @entity85 @entity1 . OUTCOME MEASURES: Health-related quality-of-life measures, including the @entity1635 ( @entity1635 )-22 questionnaire, were used. METHODS: The study used a multicenter database of 215 non-operative @entity1 with @entity85 and with minimum 2-year follow-up. Using a multivariate analysis, two groups were compared to identify possible predictors: those who reached @entity922 in the @entity158 or activity (N=86) at 2 years and those who did not reach @entity922 (N=129). A subgroup multivariate analysis of @entity1 with a deficit (potential improvement) in both @entity158 and activity (N=84) was performed. Data collection was supported by a grant from DePuy for the International Spine Study Group Foundation. RESULTS: At baseline, the non-operative @entity1 who reached @entity922 had a significantly lower @entity158 score (3.0 vs. 3.6), smaller thoracolumbar Cobb (TL Cobb) angle (29.6   vs. 36.5  ; 87 @entity1 with @entity1635 -Schwab classification of lumbar or double), lower sacral slope (33.1   vs. 36.4  ), and @entity1515 (46.5   vs. 52.8  ) (all p<.05). The @entity158 and TL Cobb were significant predictors for reaching @entity922 . The pelvic incidence minus @entity1515 (PI-LL) was significant on univariate analysis but not on multivariate analysis (7.5   vs. 2.6  ; p=.14). In the subset of severely disabled @entity1 , worse vertebral obliquity was a predictor for not achieving @entity922 (p<.05). CONCLUSIONS: Non-operative @entity85 @entity1 who achieved @entity922 in @entity1635 activity or @entity158 had a lower baseline @entity158 score and less @entity85 in the TL region. Greater baseline @entity158 offers significant room for potential improvement, which may be important in identifying @entity85 @entity1 who have the potential to reach @entity922 non-operatively. @entity85 in the TL region and associated vertebral obliquity may negatively impact potential for improvement in non-operative care.

The benefit of non-operative treatment for adult XXXX : identifying predictors for reaching a @entity922 .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENT'] @entity1635 :: ('MESH:D012600', 'Disease') :: ['Scoliosis Research Society', 'SRS'] @entity1515 :: ('MESH:D008141', 'Disease') :: ['less lumbar lordosis', 'lumbar lordosis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'SRS pain'] @entity85 :: ('MESH:D009140', 'Disease') :: ['Coronal deformities', 'Adult spinal deformity', 'coronal deformity', 'ASD'] @entity922 :: ('MESH:D013568', 'Disease') :: ['minimal clinically important difference', 'MCID']
@entity85 :: (MESH:D009140,Disease) :: ['spinal deformity']
