An outbreak of @entity5827 caused by echovirus type 9 (ECHO-9) occurred between June and August 1997 in the Chikugo area, Fukuoka, Japan. Clinical manifestations and laboratory data of 317 @entity1 with @entity5827 were analyzed. The age of the @entity1 ranged from 1 month to 12 years with the highest incidence in 4 years old @entity1 . The male: female ratio was 2.0:1.0. Symptoms of the @entity693 included @entity221 (100%), @entity10 (89.5%) and @entity1209 (85.6%). Skin rash was not frequent (2.2%) in contrast to previous reports of ECHO 9 infections. The number of white blood cells (WBC) in cerebrospinal fluid (CSF) ranged from 10 to 3,493 cells/microliter (median; 412 cells/microliter). The neutrophils were more than 50% of the WBC in CSF in one-fourth of the @entity1 at diagnosis. Enteroviruses were identified from CSF utilizing virus culture and enterovirus-specific RT-PCR, and ECHO-9 infection was determined by antibody titer of paired sera. Finally 44 @entity1 were diagnosed virologically or serologically as @entity5827 caused by ECHO-9. Sequence analysis revealed that two strains of ECHO-9 isolated from CSF in this epidemic were closely related to ECHO-9 virulent strain Barty.

Outbreak of XXXX due to ECHO-9 in northern Kyushu island in the summer of 1997.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity5827 :: ('MESH:D008582', 'Disease') :: ['aseptic meningitis'] @entity693 :: ('MESH:D008581', 'Disease') :: ['meningitis'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity1209 :: ('MESH:D020250', 'Disease') :: ['nausea and/or vomiting']
@entity5827 :: (MESH:D008582,Disease) :: ['aseptic meningitis']
