BACKGROUND: As the potentiality of deceased organ donation mostly depends on the number of @entity1620 ( @entity1620 ), the aim of this study is to quantify rates and probabilities of @entity2403 declaration in Italy. METHODS: Deaths with @entity75 (ACLDs) in the Italian ICUs have been prospectively collected. A total of 27,490 ACDLs occurred in 5 years. Age, gender, etiology, timing of @entity204 and ICU Region have been utilized for multivariate analysis. RESULTS: The global ratio of @entity2403 to ACLDs was 39.9%. The rates of ACLDs, @entity2403 and actual donors were 93.5, 37.3 and 19.7 pmp respectively. Wide variability resulted among Regions, with 148.2 ACLDs, 77.8 @entity2403 and 42 donors pmp as benchmark. The probability of being @entity2403 declared was significantly higher in @entity64 compared with @entity542 (OR 1.6, P<0.001) and in females (OR 1.5, P<0.001), with half the Regions missing around 50% of @entity2403 compared with the benchmark, particularly in elderly @entity1 . CONCLUSION: Predictable factors associated with @entity2403 declaration can be identified in ACLD management. Positive factors leading to the identification of potential organ donors, i.e., the capacity of declaring @entity2403 in all the @entity1 fulfilling @entity2403 criteria irrespective of age and etiology, could be captured in the best performing regions and reproduced throughout the Country. The implementation of simple indicators based on prospective ACLD monitoring, i.e. the declared @entity1620 to ACLDs in ICU ratio, may be helpful in achieving efficiency targets and reliable comparisons of outcomes in the identification of @entity2403 potential organ donors.

Deaths with acute XXXX in ICU: does the number of potential organ donors depend on predictable factors?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity75 :: ('MESH:D001927', 'Disease') :: ['acute cerebral lesion'] @entity542 :: ('MESH:D006259', 'Disease') :: ['head injury'] @entity1620 :: ('MESH:D001926', 'Disease') :: ['brain deaths', 'BDs'] @entity2403 :: ('MESH:D001528', 'Disease') :: ['BD', 'BD declarations'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity75 :: (MESH:D001927,Disease) :: ['cerebral lesions']
