BACKGROUND: Nutritional depletion, either macronutrient- or micronutrient-related, is common in @entity1 with @entity7623 ( @entity7623 ) for which there is often no effective treatment. We studied a group of 12 @entity1 (4 @entity1 , 8 @entity1 ; mean age, 35.7 years) who had symptoms of @entity7623 and were a subset of the Gastric ElectroMechanical Stimulation trial of gastric electrical stimulation. @entity1 ' symptoms were of long duration (7.3 years) and associated with @entity6 (3 @entity1 ) or were idiopathic (9 @entity1 ) as etiology. METHODS: The @entity1 had permanent gastric electrical stimulation devices surgically implanted after a positive trial of temporary stimulation. @entity1 had baseline measures of gastrointestinal @entity1109 ( @entity1109 ), laboratory (albumin and related) measures, weight (kg), body mass index, and route of nutrition: oral feeding, enteral tubes, or hyperalimentation, repeated at 3, 6, and 12 months. Intermediate-term follow-up was done at 1 to 2 years, and long-term follow-up was done at 5 years and included @entity344 , weekly @entity391 frequency score, and nutrition and overall health-related quality-of-life measures. RESULTS: Gastric electrical stimulation was associated with rapid improvement over the short-term in @entity1109 (35.6 at baseline to 16.6 at month 12; p < .05), body weight, body mass index, and serum albumin over the short term with most parameters improving by 3 to 6 months. Intermediate (1 to 2 years) and long-term (5 year) data showed continued improvement in @entity1109 , @entity391 frequency (weekly @entity391 frequency score 3.9 at baseline to 1.7 at 5 years; p < .01), quality-of-life measures, and maintenance of @entity1017 . CONCLUSIONS: Gastric electrical stimulation implantation resulted in improvement of nutritional parameters throughout the first 12 months, as @entity390 and @entity391 decreased and oral intake increased. This improvement in nutritional measures is maintained long-term and is associated with improvements in quality of life. Gastric electrical stimulation should be considered as a therapeutic option for any @entity1 with refractory @entity7623 and nutritional compromise.

Gastric electrical stimulation for XXXX improves nutritional parameters at short, intermediate, and long-term follow-up.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['total symptom score', 'TSS'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal TSS'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity7623 :: ('MESH:D018589', 'Disease') :: ['GP', 'drug-refractory gastroparesis']
@entity7623 :: (MESH:D018589,Disease) :: ['gastroparesis']
