Background/Aims: Concurrent chemoradiotherapy (CCRT) is considered the treatment option for locally advanced @entity788 , but accompanying @entity344 are the most common complication. With the introduction of three-dimensional conformal radiotherapy (3-D CRT) and intensity-modulated radiotherapy (IMRT), CCRT-related adverse events are expected to diminish. Here, we evaluated the benefits of radiation modalities by comparing @entity344 between 3-D CRT and IMRT. Methods: @entity1 who received CCRT between July 2010 and June 2012 in Severance Hospital, Yonsei University College of Medicine, were enrolled prospectively. The @entity1 underwent upper endoscopy before and 1 month after CCRT. Results: A total of 84 @entity1 were enrolled during the study period. The radiotherapy modalities delivered included 3D-CRT (n=40) and IMRT (n=44). The median follow-up period from the start of CCRT was 10.6 months (range, 3.8 to 29.9 months). The symptoms of @entity2210 , @entity390 / @entity391 , and @entity294 did not differ between the groups. Upper endoscopy revealed significantly more @entity10189 in the 3-D CRT group (p=0.003). The modality of radiotherapy (3D-CRT; odds ratio [OR], 11.67; p=0.011) and @entity5 location (body of pancreas; OR, 11.06; p=0.009) were risk factors for @entity344 . Conclusions: IMRT is associated with significantly fewer @entity130 among @entity1 treated with CCRT for @entity788 .

A Comparison of Gastrointestinal Toxicities between Intensity-Modulated Radiotherapy and Three-Dimensional Conformal Radiotherapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic cancer'] @entity10189 :: ('MESH:D010437', 'Disease') :: ['gastroduodenal ulcers'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal toxicities'] @entity2210 :: ('MESH:D004415', 'Disease') :: ['dyspepsia'] @entity130 :: ('MESH:D014947', 'Disease') :: ['gastroduodenal injuries']
@entity788 :: (MESH:D010190,Disease) :: ['Pancreatic Cancer']
