UNASSIGNED: Background and study aims: The number of @entity1 with @entity740 ( @entity740 ) is increasing worldwide and @entity356 sometimes occurs with @entity740 . However, the safety and feasibility of endoscopic submucosal dissection (ESD) for @entity1 with @entity740 are not clear. The aim of this study is to clarify the feasibility and safety of gastric ESD for @entity1 with @entity740 . @entity1 and methods: This was a multicenter retrospective cohort study. In total, 144 @entity1 with @entity740 who underwent gastric ESD between May 2003 and October 2012 were enrolled. The @entity1 were divided into three groups: stage 3 (estimated glomerular filtration rate [eGFR]: 30-59mL/min), stage 4 (eGFR: 15-29mL/min), and stage 5 (eGFR:<15mL/min) according to the @entity8 Improving Global Outcomes Guidelines. The en bloc and curative resection rates and complications were assessed as short-term outcomes. Overall survival was analyzed using Kaplan-Meier methods. Results: In total, 92 @entity1 were in stage 3 @entity740 ; 23 in stage 4; and 29 in stage 5, including 19 @entity1 in hemodialysis. The en bloc resection rate was 95.8%. Post-ESD @entity548 was observed in four @entity1 with stage 5 @entity740 (13.8%), three with stage 4 (13.0%), and one with stage 3 (1.1%). All @entity548 could be controlled by endoscopic hemostasis, but five @entity1 required blood transfusion. Perforation occurred in two @entity1 (6.9%) with stage 5 @entity740 , none (0%) with stage 4, and two (4.3%) with stage 3.Multivariate Poisson regression analysis revealed @entity740 stage 4 was a critical factor related to @entity548 , whereas @entity6 and @entity740 stage 5, which largely consist of @entity1 receiving hemodialysis, were not. The median observation period of @entity1 who achieved curative resection was 25.9 months (range 0.8-112.7 months) and the 3-year overall survival rate was 92.5%. Conclusions: Estimated GFR is a significant independent predictive factor of post-ESD @entity548 in @entity1 with @entity740 .

XXXX is an independent risk factor for @entity548 after gastric ESD.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['Kidney Disease'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity740 :: ('MESH:D051436', 'Disease') :: ['CKD', 'chronic kidney disease'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer']
@entity8 :: (MESH:D007674,Disease) :: ['Renal dysfunction']
