OBJECTIVE: The aim of the study was to investigate the clinicopathological features of @entity788 at different stages using autopsy results. METHODS: We retrospectively evaluated 8399 consecutive cases of autopsy performed between 1972 and 2013 at our geriatric hospital. RESULTS: Macroscopic pancreatic lesions were detected in 6.13% of the cases. Primary and secondary @entity788 were observed in 2.88% and 2.10% of the cases, respectively. Most @entity5 were @entity420 (193 cases [2.31%]; mean @entity1 age, 78.09 years) with a peak incidence at 50 to 59 years. Occult @entity420 was discovered incidentally in 15 cases, with distant @entity3 present in 26.67% of those. Microscopically, occult and advanced @entity5 exhibited similar characteristics such as hyalinized @entity82 , @entity39 , invasion into vessels, peripancreatic fat tissues, and extrapancreatic nerve plexus. @entity2355 immunohistochemical expression levels were also similar. Occult @entity5 incidence increased with age. @entity1 aged 85 years or older had shorter survival, a small @entity5 size, and a low incidence of lymph node @entity3 . Approximately 8% of @entity788 progressed asymptomatically and were discovered incidentally at autopsy. CONCLUSIONS: @entity788 in elderly @entity1 tend to progress asymptomatically, but once symptoms develop, they are more often fatal than those in younger @entity1 .

Clinicopathological Features of 15 Occult and 178 Clinical Pancreatic Ductal Adenocarcinomas in 8339 Autopsied Elderly XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity788 :: ('MESH:D010190', 'Disease') :: ['Pancreatic cancers', 'pancreatic cancer', 'pancreatic invasive ductal adenocarcinomas', 'pancreatic tumors'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrous stroma'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumors', 'cancer', 'tumors'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity2355 :: ('4582', 'Gene') :: ['Mucin 1 and 2'] @entity420 :: ('MESH:D000230', 'Disease') :: ['invasive ductal adenocarcinoma', 'invasive ductal adenocarcinomas']
@entity1 :: (9606,Species) :: ['Patients']
