OBJECTIVES: The purpose of this retrospective study was to analyse the pathogenesis and the treatment strategies of @entity1121 ( @entity1121 ) with the concomitant mitral @entity340 . METHODS: Between October 1996 and December 2009, 76 @entity1 with the @entity1121 underwent the ventricular septal myotomy-myectomy in Fuwai hospital. There were 51 males and 25 females aged between 6 and 68 years (mean: 37.18    15.85 years) old. All the @entity1 had left ventricular outflow tract (LVOT) obstruction with a resting or physically provoked gradient of >= 50 mmHg and the systolic anterior movement (SAM) of the mitral leaflets, and 64 @entity1 had @entity339 ( @entity339 ). These @entity1 underwent the ventricular septal myotomy-myectomy under general anaesthesia and cardiopulmonary bypass. The concomitant surgical procedures included mitral valve replacement (MVR, n = 14) and @entity339 ( @entity339 , n = 12). RESULTS: All the surgical procedures were technically successful. In comparison with the preoperative conditions, the resting LVOT gradient had marked reduction (99.73    38.61-23.55    16.53 mmHg, P < 0.001), the mean septal thickness was decreased from 26.23    5.24 to 17.33    4.74 mm. @entity339 had significant improvement, SAM was resolved completely or only mild. Four @entity1 (5.3%, 4/76) died during the hospital stay. The causes of @entity204 included severe @entity943 with @entity998 , severe @entity810 , @entity326 with @entity810 with @entity998 . The others were followed up for 5-18 years: there were no deaths. Moderate @entity339 was noted in two @entity1 at 2 months or 2 years after operation respectively, who had undergone @entity339 with the edge-to-edge technique stitch procedure, and only had mild or trivial @entity339 at hospital discharge, of whom one received repeat operation with MVR and the other is still in follow-up. All surviving @entity1 were evaluated as New York Heart Association Functional class I or II, and had a significant increase in physical capacity and a significant reduction in disabling symptoms. CONCLUSIONS: The ventricular septal myotomy-myectomy can be performed successfully for the severe obstructive @entity1121 and @entity339 with the low morbidity and mortality and excellent survival in the great majority of @entity1 . But for the few @entity1 with the intrinsic @entity339 or MVR may be required, and MVR should be performed only as a priority choice for the inherent risks of prosthetic valves and anticoagulation therapy.

The surgical management of @entity1121 with the concomitant mitral XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral valve plasty', 'MVP', 'mitral valve disease, the concomitant MVP', 'MR', 'mitral regurgitation'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmias'] @entity998 :: ('MESH:D002303', 'Disease') :: ['low cardiac output'] @entity326 :: ('MESH:D012772', 'Disease') :: ['septic shock'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute renal dysfunction and the complete AV block', 'acute renal failure'] @entity340 :: ('MESH:D006349', 'Disease') :: ['valve abnormalities'] @entity1121 :: ('MESH:D002312', 'Disease') :: ['HOCM', 'hypertrophic obstructive cardiomyopathy'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity340 :: (MESH:D006349,Disease) :: ['valve abnormalities']
