PURPOSE: To describe the therapeutic results, with the aim to contribute to improving the care of @entity1 with @entity2946 . @entity1 AND METHODS: A retrospective study of 69  cases of @entity2946 collected in the university hospital Ibn Rochd of Casablanca between 2000  and 2012. RESULTS: Fifty-three @entity1 with an average age of 9 years and 16 adults with an average age of 32.4 years were included in the study. Thirty-seven @entity1 and eight adults suffered from a high-risk @entity5 . The radiotherapy was received by all @entity1 with a mean dose of 36Gy to the whole brain and 54Gy in the posterior fossa. All @entity1 in the paediatric group and 10 @entity1 in the adult group received concomitant chemotherapy, 44 @entity1 and four adults received adjuvant chemotherapy. @entity5 recurrence was observed in 17 @entity1 after a mean follow-up period of 38 months. These recurrences were observed in five adults after a mean follow-up period of 42 months. The posterior fossa was the main site of relapses. Overall survival was 77.7% for the @entity1 and 61% for the adults. Overall survival was better (70% versus 25%) when the interval between radiotherapy and surgery was less than 40 days in the paediatric group. The recurrence rate was significantly higher for the high-risk group: 41% versus 13% for the standard risk. In the adult group, overall survival differences according to the risk group were significant (100% for the standard risk versus 37.5% for the high risk). CONCLUSION: The overall survival and recurrences rate obtained are encouraging. The risk group and time between surgery and radiotherapy were prognostic factors with significant impact on survival depending on the age group. We recommend reducing these times to improve therapeutic results.

[Therapeutic outcomes of XXXX in Casablanca from 2000 to 2012].

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Tumour', 'tumour'] @entity2946 :: ('MESH:D008527', 'Disease') :: ['medulloblastoma']
@entity2946 :: (MESH:D008527,Disease) :: ['medulloblastoma']
