BACKGROUND: Partial nephrectomy for small renal masses (SRM) may be useful for preserving renal function, but is technically more difficult than radical nephrectomy. Cryoablation may be performed under local anesthesia. The objective of the present study is to assess the safety and therapeutic efficacy of cryoablation with @entity4831 marking for SRM. METHODS: Cryoablation therapy was performed on 42 @entity1 under local anesthesia. Their median age was 74  years (31-91). The median @entity5 diameter was 21  mm (10-42). Responses to the treatment were evaluated using modified Response Evaluation Criteria in @entity5 (mRECIST) by contrast-enhanced CT. In six @entity1 (14.3%) for whom it was not possible to use contrast medium, plain CT findings were assessed according to Response Evaluation Criteria in @entity5 (RECIST). RESULTS: Twenty-nine (69%) and five (12%) @entity1 achieved complete responses (CR) and partial responses (PR), respectively, while four (10%) and four (10%) @entity1 each had @entity66 ( @entity66 ) and @entity74 ( @entity74 ) after the first course of therapy. A second course of cryoablation therapy with @entity4831 marking was performed on three out of four @entity1 with @entity74 after the first course of therapy, and resulted in a total of 32 @entity1 achieving CR (76%). Four (36.4%) out of 11 @entity1 for whom @entity4831 marking was not conducted had @entity74 , whereas none of the 31 @entity1 for whom @entity4831 marking was conducted had @entity74 . All grade complications were reported in 11 (24.4%) @entity1 while grade 3 in two (4.4%) @entity1 . 11 (24.4%) A significant difference was observed in postoperative hemorrhagic events in all grades (18% in @entity1 undergoing cryoablation without @entity4831 marking vs. 0% in @entity1 undergoing cryoablation without @entity4831 marking). CONCLUSIONS: Although further studies involving more @entity1 are needed in order to evaluate long-term results, cryoablation therapy appears to be a useful treatment option for SRM. Preoperative marking with @entity4831 was helpful for improving  complication and survival rates with cryoablation.

Preoperative XXXX marking and its role on survival and complication rates of CT-guided cryoablation for small renal masses.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['stable disease', 'SD'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Solid Tumors'] @entity4831 :: ('MESH:D004998', 'Chemical') :: ['lipiodol'] @entity74 :: ('MESH:D030342', 'Disease') :: ['PD', 'progressive disease']
@entity4831 :: (MESH:D004998,Chemical) :: ['lipiodol']
