BACKGROUND: The right-to-left shunt at the atrial level is responsible for @entity519 in @entity1 with @entity118 . OBJECTIVES: This study investigated the mechanism of @entity519 in @entity1 with @entity118 by measuring the @entity4095 in both the right and left upper pulmonary veins. SUBJECTS AND METHOD: We prospectively measured the @entity4095 in the femoral artery and the right and left upper pulmonary veins during cardiac catheterization in 13 adults (median age, 53 years) and 7 @entity1 (median age, 7 years) with secundum @entity118 . The adults and @entity1 were studied consecutively. Contrast echocardiography was performed to evaluate right-to-left shunt in all adults. RESULTS: Among the @entity1 , there were no @entity1 showing @entity519 , and there was no difference in the @entity4095 (+/-SD) between the right and left upper pulmonary veins (right, 100+/-3.8 mm Hg vs left, 100+/-7.8 mm Hg; p = 0.92). However, @entity519 was present in 11 of the 13 adult @entity1 , although contrast echocardiography showed more than a moderate degree of right-to-left shunt in only four adults. The @entity4095 was lower in the left upper pulmonary vein than it was in the right upper pulmonary vein in all adult @entity1 (right, 91.6+/-13.8 mm Hg vs left, 73.0+/-11.5 mm Hg; p < 0.0001). CONCLUSION: The @entity4095 was lower in the left upper pulmonary vein than it was in the right upper pulmonary vein in adults with @entity118 . Care must be taken in measuring pulmonary blood flow if the @entity4095 in the left upper pulmonary vein is low enough to influence @entity26 content. The decreased @entity4095 in the left upper pulmonary vein may contribute to @entity519 in addition to right-to-left shunt at the atrial level in adults with @entity118 .

Partial pressure of @entity26 is lower in the left upper pulmonary vein than in the right in adults with @entity118 : difference in XXXX between the right and left pulmonary veins.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity519 :: ('MESH:D000860', 'Disease') :: ['arterial hypoxemia'] @entity118 :: ('MESH:D006344', 'Disease') :: ['atrial septal defect'] @entity4095 :: ('MESH:C093415', 'Chemical') :: ['P(O2)']
@entity4095 :: (MESH:C093415,Chemical) :: ['P(O2)']
