The diagnostic procedures in @entity1 with suspected @entity409 -with or without known @entity167 consumption-should be standardized and generally accepted. We therefore present a guideline, summarizing the current concepts of etiology, diagnostic as well as differential diagnostic of @entity1 with @entity409 . Alcoholic as well as and @entity1561 are characterised by lipid deposition in hepatocytes. The diagnosis of @entity1560 is made when lipid deposition exceeds 5% of hepatocytes, while involvement of more than 50% is @entity1560 ". An additional inflammatory reaction leads to alcoholic (ASH) or @entity7936 ( @entity7936 ). @entity1560 is present when both inflammatory infiltrates of mixed cells in the small liver lobules as well as liver cell injury in terms of ballooning can be detected. Liver biopsy represents the "golden standard" for confirming diagnosis and determining inflammatory activity and potential @entity82 of @entity409 . The differential diagnosis of ASH vs. @entity7936 cannot be made on the basis of histological criteria alone. @entity1560 , inflammatory changes and hepatocytic injury can be semiquantified as a "Brunt Score" or "NAS" (NAFLD activity score), providing the basis on which to decide whether or not @entity1560 is present. @entity1 at increased risk of developing a @entity1560 possess an increased risk of developing chemotherapy-associated @entity1560 . Histologically, pediatric @entity7936 differs from adult @entity7936 and is often only clinically manifest through a mild if persistent elevation in transaminases.

Histopathological diagnosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'People'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity1560 :: ('MESH:D005234', 'Disease') :: ['Steatohepatitis', 'Steatosis', 'fatty liver', 'steatohepatitis', 'called "fatty liver', 'steatosis'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity409 :: ('MESH:D008107', 'Disease') :: ['fatty liver disease'] @entity7936 :: ('MESH:D005235', 'Disease') :: ['NASH', 'non-alcoholic steatohepatitis'] @entity1561 :: ('MESH:D065626', 'Disease') :: ['non-alcoholic fatty liver']
@entity1561 :: (MESH:D065626,Disease) :: ['non-alcoholic and alcoholic fatty liver disease']
