PURPOSE: Palmar @entity1119 (PH) is a common illness that significantly impacts Quality of Life (QOL). @entity11440 offers excellent short-term results, but long-term follow-up results are limited. We evaluated its effectiveness in a large group of @entity1 who did not have surgery and who had at least 6 months of follow-up. METHODS: Between September 2007 and September 2013, 570 consecutive @entity1 were enrolled in our institutional protocol regarding the "pharmacological-first" treatment of primary PH with @entity11440 . Fifty-nine were lost to follow-up, and the data were available for 511 @entity1 treated for at least 6  weeks. Data recorded at the start of the protocol, 6  weeks after beginning treatment, and during @entity1 ' final visits were analyzed. RESULTS: 112 @entity1 (21.9  %) did not improve and were referred for surgery (sympathectomy). Eight (1.56  %) developed significant side effects (e.g., @entity2133 ) and discontinued therapy. Thirty (5.9  %) preferred surgery over pharmacological treatment. 111 have not yet received treatment for 6  months. The 246 @entity1 with more than 6  months of follow-up (median 16  months, range 6-72) were analyzed, as follows: 90.2  % experienced moderate or great improvement in their PH; 90.34  % experienced improvement at other sites of @entity1119 following a median of 16  months. CONCLUSION: Among @entity1 with good initial responses to @entity11440 , more than 90  % experienced moderate or great improvement in their palmar sweating, as well as in their @entity1119 in other sites, after 6  months. The results were particularly favorable in those @entity1 with BMI  <25  kg/m(2), and in those who noted an improved QOL after 6  weeks.

Long-term results of @entity11440 treatment for palmar XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2133 :: ('MESH:D014987', 'Disease') :: ['dry mouth'] @entity1119 :: ('MESH:D006945', 'Disease') :: ['hyperhidrosis'] @entity11440 :: ('MESH:C005419', 'Chemical') :: ['Oxybutynin', 'oxybutynin']
@entity1119 :: (MESH:D006945,Disease) :: ['hyperhidrosis']
