The aim of this report was to investigate the contribution of @entity1533 / @entity3098 alleles to  the expression of @entity5 ( @entity5 ) and @entity2784 ( @entity2784 ) in  Mexican @entity1 . A total of 257 @entity1 were included in the study: 61with @entity2784 ( @entity2784 ), 30 with high-grade ( @entity2784 ), 73 with @entity5 and 93 healthy females. All were Mexican Mestizos. For HLA class II typing, PCR-SSOP methodology was used. @entity1799 viral DNA was detected by PCR with specific primers for E6-E7 region. @entity1799 was found in 52% of the @entity1 with @entity5  as well as in 19% of @entity1 with @entity2784 and in 12.5% of females with @entity2784 . @entity1533   04:03 (OR  = 5.88) was found increased in @entity1 with @entity2784 as compared with controls, although significance (p  = 0.04) was lost after correction (pc  =NS). @entity1533   04:03 seems to influence the risk for developing @entity2784 , disregarding the presence of @entity1799 . @entity1533   01:01 (OR  = 0.12; p  = 0.01) may confer protection to the development of @entity5 . An analysis performed stratifying by the presence of @entity1799 infection showed that the frequency of @entity1533   04:07 (OR  = 2.71) was increased in @entity5 @entity1 infected with @entity1799 , confirming that the HLA association is HPV dependent. These results shed light on the influence that this virus may have in the expression of @entity5 in the susceptible host. Genetic background is, therefore, a crucial factor in understanding the etiopathogenesis of @entity5 in HPV-positive @entity1 .

@entity1799 and XXXX alleles are associated with cervical carcinoma in Mexican Mestizo @entity1 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity3098 :: ('3119', 'Gene') :: ['DQB1'] @entity5 :: ('MESH:D009369', 'Disease') :: ['CC', 'cervical cancer'] @entity1799 :: ('333760', 'Species') :: ['HPV-16'] @entity2784 :: ('MESH:D065310', 'Disease') :: ['squamous intraepithelial lesion', 'SIL', 'LSIL', 'HSIL', 'low-grade squamous intraepithelial lesions'] @entity1533 :: ('3123', 'Gene') :: ['HLA-DRB1']
@entity1533 :: (3123,Gene) :: ['HLA-DRB1']
