UNASSIGNED: Dietary patterns with @entity65 have been recommended, but the relative contributions of individual foods and food components, alone or in combination, remain undefined. Male @entity6970 (-/-) @entity19 were fed either a purified AIN-93G control diet, a @entity8928 ( @entity8928 ), or a @entity8928 with 10% @entity523 powder (TP), 2% soy germ (SG), or the combination, for 4 wk (n = 10 per group). Plasma total @entity165 and @entity1674 were measured with enzymatic colorimetric kits, and @entity35616 ( @entity35616 ) was measured by ELISA. Liver lipids were extracted with @entity3636 : @entity1042 , and @entity1674 , free and esterified @entity165 measured with enzymatic colorimetric kits. Expression of @entity52501 , @entity38296 , @entity34737 , and @entity34738 in the liver was determined by quantitative polymerase chain reaction. Sections of the aortic root and aorta were cut and stained with @entity1710 and @entity1711 (H_E) to assess extent of @entity731 . @entity8928 -fed animals had greater liver and adipose weights, plasma @entity165 and @entity35616 , hepatic lipids, and @entity731 than AIN-93G animals. TP and SG did not decrease @entity731 as measured by H_E-stained sections of the aortic root, aortic arch, and descending aorta. The TP diets further increased plasma @entity165 , but also led to increased expression of the @entity34737 /8 transporters involved in @entity165 efflux. Addition of SG alone to the @entity8928 attenuated @entity8928 -induced increases in plasma @entity165 , liver lipids, and gonadal adipose weight. The results of this study do not support the use of either TP or SG for reduction of @entity731 , but suggest some beneficial effects of SG on lipid metabolism in this model of @entity65 .

Effects of @entity523 and Soy Germ on Lipid Bioaccumulation and XXXX in @entity6970 (-/-) @entity19 .

@entity38296 :: ('13122(Tax:10090)', 'Gene') :: ['Cyp7a1'] @entity52501 :: ('104086(Tax:10090)', 'Gene') :: ['Cyp27a1'] @entity6970 :: ('11816(Tax:10090)', 'Gene') :: ['ApoE'] @entity8928 :: ('MESH:D020241', 'Disease') :: ['Western diet', 'WD'] @entity19 :: ('10090', 'Species') :: ['mice'] @entity1042 :: ('MESH:D000432', 'Chemical') :: ['methanol'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity35616 :: ('111345(Tax:10090)', 'Gene') :: ['SAA', 'serum amyloid A'] @entity3636 :: ('MESH:D002725', 'Chemical') :: ['chloroform'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['eosin'] @entity34737 :: ('27409(Tax:10090)', 'Gene') :: ['Abcg5'] @entity34738 :: ('67470(Tax:10090)', 'Gene') :: ['Abcg8'] @entity523 :: ('4081', 'Species') :: ['tomato'] @entity1710 :: ('MESH:D006416', 'Chemical') :: ['hematoxylin'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic lesions', 'atherosclerosis'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease', 'cardiovascular benefits'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerosis']
