BACKGROUND: A simple test of aerobic fitness for @entity1 with @entity131 ( @entity131 ) that is valid, reliable, and responsive to change is needed to provide clinicians a functional measure of cardiorespiratory capacity. OBJECTIVE: The purpose of this study was to examine the validity and responsiveness to change of the Six-Minute Walk Test (6MWT) in individuals with @entity131 . DESIGN: A cohort, pretest-posttest, comparison study was conducted. METHODS: Twenty-one @entity1 performed the 6MWT upon admission to and prior to discharge from a postacute rehabilitation facility. Heart rate and distance traveled were recorded. A physiologic cost index (PCI) (beats per meter) was calculated based on steady-state heart rate. At discharge, all @entity1 were able to perform a graded treadmill exercise test to exhaustion during which peak @entity26 consumption ( @entity4962 ) was measured. RESULTS: Between admission and discharge, mean total distance increased from 342.6 m (SD=127.0) to 408.9 m (SD=124.2), and work increased from 27,185 kg  m (SD=10,528) to 34,114 kg  m (SD=12,057). The effect size indexes were 1.10 and 1.12 for distance and work, respectively. Correlations (r) between the discharge peak @entity4962 and the discharge 6MWT distance, PCI, and work were .58, -.61, and .47, respectively. LIMITATIONS: Stratification by gait speed may have improved responsiveness, especially for the slow ambulators. CONCLUSIONS: All measures correlated well with peak Vo(2), establishing an acceptable level of criterion-related (concurrent) validity. The addition of heart rate and calculating the PCI was only slightly better at predicting peak Vo(2), albeit nonsignificant, than a simple measure of total distance. The 6MWT provides a good estimate of peak aerobic capacity, and some measures are more responsive to change than others in @entity1 recovering from @entity131 .

Responsiveness and validity of the six-minute walk test in individuals with XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity131 :: ('MESH:D001930', 'Disease') :: ['TBI', 'traumatic brain injury'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity4962 :: ('CHEBI:30046', 'Chemical') :: ['Vo(2)']
@entity131 :: (MESH:D001930,Disease) :: ['traumatic brain injury']
