OBJECTIVES: To report the experience with Middle East respiratory syndrome @entity7822 at a single center in Saudi Arabia. METHODS: Cases of laboratory-confirmed MERS-CoV occurring from October 1, 2012 to May 31, 2014 were reviewed retrospectively. Information sources included medical files, @entity281 control outbreak investigations, and the preventive medicine database of MERS-CoV-infected @entity1 . Data were collected on clinical and epidemiological aspects and outcomes. RESULTS: Seventy consecutive @entity1 were included. @entity1 were mostly of older age (median 62 years), male (46, 65.7%), and had healthcare acquisition of @entity281 (39, 55.7%). Fever (43, 61.4%), @entity1353 (42, 60%), and cough (38, 54.3%) were the most common symptoms. The majority developed @entity55 (63, 90%) and required intensive care (49, 70%). Infection commonly occurred in clusters. Independent risk factors for severe @entity281 requiring intensive care included concomitant @entity281 (odds ratio (OR) 14.13, 95% confidence interval (CI) 1.58-126.09; p=0.018) and low albumin (OR 6.31, 95% CI 1.24-31.90; p=0.026). Mortality was high (42, 60%), and age >= 65 years was associated with mortality (OR 4.39, 95% CI 2.13-9.05; p<0.001). CONCLUSIONS: MERS-CoV can cause severe @entity281 requiring intensive care and has a high mortality. Concomitant @entity281 and low albumin were found to be predictors of severe @entity281 , while age >= 65 years was the only predictor of mortality.

Clinical aspects and outcomes of 70 @entity1 with Middle East respiratory syndrome XXXX : a single-center experience in Saudi Arabia.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'infections'] @entity7822 :: ('MESH:D018352', 'Disease') :: ['coronavirus (MERS-CoV) infection']
@entity7822 :: (MESH:D018352,Disease) :: ['coronavirus infection']
