BACKGROUND AND OBJECTIVES: Unplanned excisions of soft-tissue @entity242 of the extremities occur commonly. Our goal was to evaluate the presence of @entity66 , the treatment outcomes as they relate to local and distant recurrence and 5-year survival, and the limb functional outcomes in @entity1 with unplanned @entity242 excision who were treated with re-excision and adjuvant therapy. METHODS: Between 1993 and 1999, 42 @entity1 presented to our institution after unplanned excision of soft-tissue @entity242 . Of those 42 @entity1 , 38 without gross @entity66 or metastatic lesions formed the basis of this review. All 38 @entity1 underwent revision wide excision; most (31) also received adjuvant therapy (radiation and/or chemotherapy). Clinical data were obtained from analysis of @entity1 records and radiographic studies. Univariate analysis was performed with logistical regression, and multivariate analysis was performed with Cox modeling. RESULTS: The overall 5-year survival rate was 91.3% and the disease-free 5-year survival rate was 82.2%. Univariate analysis showed that stage-III disease (American Joint Committee on Cancer classification of soft-tissue @entity242 ), lesions below the fascia, a histologic high-grade, and the development of organ @entity3 were statistically significant factors for mortality. @entity5 also was significant for mortality on multivariate analysis. Only stage-III disease was significant for the development of local recurrence. Eighty-four percent of the @entity1 had good to excellent functional outcomes. CONCLUSIONS: Re-excision with adjuvant therapy proved to be a safe and effective method for treating the disease and preserving limb function.

Outcomes of re-excision after unplanned excisions of soft-tissue XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['residual disease'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma', 'sarcomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Stage-III disease'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity242 :: (MESH:D012509,Disease) :: ['sarcomas']
