OBJECTIVE: The purpose of the study was to examine the oncological and functional outcomes of multimodality therapy for @entity1 with advanced @entity1177 that invaded the orbit. STUDY DESIGN: Retrospective study. METHODS: The medical records of 26 @entity1 with orbital invasion were retrospectively analyzed. The @entity1 group consisted of 16 @entity1 and 10 @entity1 , with a median age of 58 years. The mean follow-up period was 73 months. The most common disease was @entity957 . Seven @entity1 had @entity66 . All @entity1 underwent simultaneous combined therapy consisting of conservative surgery through a sublabial incision, radiotherapy, and regional chemotherapy. @entity1 with @entity66 were treated with either irradiation or selective neck dissection. RESULTS: The 5- and 10-year overall survival rates were 68% and 51%, respectively. The 5- and 10-year local control rates were 66% and 51%, respectively. Overall survival rates and local control rates were significantly worse in @entity1 with disease other than @entity957 . Local control rates were significantly worse in @entity1 with orbital apex disease than in @entity1 without orbital apex disease. All 26 @entity1 , despite orbital involvement, retained their orbital contents. Nineteen of these @entity1 demonstrated adequate ocular function. CONCLUSIONS: Combined therapy with conservative surgery, radiotherapy, and regional chemotherapy is an effective method for local control and preservation of ocular function. However, performing orbital conservation procedure in @entity1 with disease other than @entity957 and with orbital apex disease must be considered carefully.

Results of orbital preservation for advanced XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'patient', 'men'] @entity1177 :: ('MESH:D008444', 'Disease') :: ['malignant maxillary sinus tumors'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity66 :: ('MESH:D004194', 'Disease') :: ['nodal disease']
@entity1177 :: (MESH:D008444,Disease) :: ['malignant maxillary sinus tumors']
