PURPOSE: Intrastromal Ferrara ring segments were inserted in eyes with severe @entity9042 to evaluate safety and efficacy of this procedure. METHODS: Intrastromal Ferrara ring segments were placed in 36 eyes of 35 @entity1 with severe @entity9042 , who were evaluated after 12 months of follow-up. All @entity1 had highly disabling visual acuity, contact lens intolerance, and a previous indication for penetrating keratoplasty. Statistical analysis included preoperative and postoperative uncorrected visual acuity, best spectacle-corrected visual acuity, manifest refraction, anterior chamber depth, keratometry, and pachymetry. RESULTS: No @entity1 had a loss of visual acuity. Uncorrected visual acuity improved in 28 eyes (77.78%) and best spectacle-corrected visual acuity improved in 29 eyes (80.56%). Spherical equivalent refraction decreased from -7.29 +/- 3.12 D to -4.80 +/- 3.04 D at 12 months after Ferrara intrastromal ring segment implantation. Corneal topography and ultrasound biomicroscopy showed corneal flattening, demonstrated by thinning of the central cornea and a reduction in anterior chamber depth. Segment decentration occurred in one eye (2.7%), asymmetric positioning of the segments in two eyes (5%), inadequate depth in two eyes (5%), migration of the segments in two eyes (5%), segment extrusion in five eyes (13.8%), @entity2024 in one eye (2.7%), @entity23081 (2.7%), and @entity4 in one eye (2.7%). CONCLUSIONS: With these early results, Ferrara intrastromal ring segments appear to be an alternative for the treatment of severe @entity9042 .

Ferrara intrastromal corneal ring segments for severe XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity4 :: ('MESH:D004487', 'Disease') :: ['hydrops'] @entity23081 :: ('MESH:D015818', 'Disease') :: ['bacterial keratitis in one eye'] @entity9042 :: ('MESH:D007640', 'Disease') :: ['keratoconus'] @entity2024 :: ('MESH:D003231', 'Disease') :: ['conjunctivitis']
@entity9042 :: (MESH:D007640,Disease) :: ['keratoconus']
