We performed an open, prospective, randomized, controlled study of the incidence of major organ complications in 420 @entity1 undergoing routine coronary artery bypass graft surgery with or without @entity1514 epidural anesthesia and @entity1337 ( @entity1041 ). All @entity1 received a standardized general anesthetic. Group @entity1041 received @entity1041 for 96 h. Group GA (general anesthesia) received narcotic @entity1337 for 72 h. Both groups received supplementary oral @entity1337 . Twelve @entity1 were excluded-eight in Group @entity1041 and four in Group GA-because of incomplete data collection. New @entity943 occurred in 21 of 206 @entity1 (10.2%) in Group @entity1041 compared with 45 of 202 @entity1 (22.3%) in Group GA (P = 0.0012). Pulmonary function (maximal inspiratory lung volume) was better in Group @entity1041 in a subset of 93 @entity1 (P < 0.0001). Extubation was achieved earlier (P < 0.0001) and with significantly fewer @entity1729 in Group @entity1041 ( @entity1041 = 31 of 206, GA = 59 of 202; P = 0.0007). There were significantly fewer @entity1 with acute @entity911 (GA = 11 of 202, @entity1041 = 3 of 206; P = 0.031) and @entity810 (GA = 14 of 202, @entity1041 = 4 of 206; P = 0.016) in the @entity1041 group. The incidence of @entity64 was insignificantly less in the @entity1041 group (GA = 6 of 202, @entity1041 = 2 of 206; P = 0.17). There were no neurologic complications associated with the use of @entity1041 . We conclude that continuous @entity1041 significantly improves the quality of recovery after coronary artery bypass graft surgery compared with conventional narcotic @entity1337 .

A prospective randomized study of the potential benefits of XXXX epidural anesthesia and @entity1337 in @entity1 undergoing coronary artery bypass grafting.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1041 :: ('MESH:D013662', 'Chemical') :: ['TEA'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity1514 :: ('MESH:D013896', 'Disease') :: ['thoracic'] @entity911 :: ('MESH:D003221', 'Disease') :: ['confusion'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['lower respiratory tract infections'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute renal failure'] @entity943 :: ('MESH:D001145', 'Disease') :: ['supraventricular arrhythmias']
@entity1514 :: (MESH:D013896,Disease) :: ['thoracic']
