INTRODUCTION: Totally thoracoscopic (TT) epicardial ablation combined with endocardial catheter ablation is an emerging treatment for persistent AF. The effects of timing of the TT and endocardial portion on @entity1129 /AF recurrence are not known. METHODS: We retrospectively analyzed @entity1 undergoing TT staged versus simultaneous hybrid AF ablation at our institution. @entity943 free outcome was compared using time to recurrence (AF or @entity1129 greater than 30 seconds after a 3-month blanking period from endocardial ablation) at 12 months. All subjects had continuous ILR or PM monitoring. RESULTS: Eighty-three @entity1 (52 same-day, 31 staged) underwent TT hybrid AF ablation. Recurrence was observed in 23 (29%) @entity1 at a median time of 147 days (IQR 91, 238). In univariate analysis, a staged approach significantly increased the likelihood of detecting incomplete PVI (OR 6 [95% CI 2-17] p = 0.001). However, only longstanding persistent AF (LSP-AF) status predicted recurrence (HR 4 [95% CI 1.4-12] p = 0.01). Neither a staged approach (HR 1.0 [95% CI 0.4-2.4] p = 0.9), nor detection of incomplete PVI (HR 0.9 [95% CI 0.4-2.3] p = 0.8) predicted time to first AF/ @entity1129 recurrence. CONCLUSIONS: Staged hybrid ablation of AF significantly increases the likelihood of discovering incomplete PVI at the time of endocardial mapping versus a same-day procedure. However, the staged approach did not improve time to first @entity1129 /AF recurrence. This article is protected by copyright. All rights reserved.

Staged Versus Simultaneous Thoracoscopic Hybrid Ablation for Persistent Atrial Fibrillation does not Affect Time to Recurrence of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity943 :: ('MESH:D001145', 'Disease') :: ['Arrhythmia'] @entity1129 :: ('MESH:D001260', 'Disease') :: ['AT']
@entity943 :: (MESH:D001145,Disease) :: ['Atrial Arrhythmia']
