OBJECTIVE: To summarize the complications after endorectal pull-through radical operation, Soave procedure, for @entity1963 . METHODS: Clinical data of 286 cases with @entity1963 who received Soave procedure and were proved by postoperative pathology in our hospital from February 2003 to February 2010 were analyzed retrospectively. All the @entity1 were diagnosed with barium enema and anorectal manometry. Among them, 233 cases(81.5%) were identified during neonatal period. All the @entity1 underwent cleansing enema and @entity384 immediately after definite diagnosis. Radical operation with Soave endorectal pull-through procedure, including simple transanal endorectal pull-through in 251 cases(87.8%), transabdominal approach in 17 cases (5.9%), laparoscopy-assisted endorectal pull-through in 18 cases (6.3%). The operations were performed in 54 cases (18.9%) within 3 months of age, in 183 cases (64.1%) between 3 and 6 months, in 38 cases(13.3%) between 6 months and one year, in 10 cases (3.5%) older than 1 year. The rectosigmoid was resected in 259 cases. Subtotal colectomy was performed in 25 cases, and total colectomy in 2 cases. Postoperative regular anal dilation lasted for 6 months. A total of 286 cases (male:250, female:36) were followed up for 2 to 5 years. RESULTS: There was wound infection in 1 case, ileus in 1 cases, anastomotic stricture in 1 case, which was cured by continuous anal dilation. Two cases had @entity1142 and received re-operation because of refractory to conservative therapy for 6 months. @entity6204 was found in 63 cases(22.0%) and was healed within 3 months, except 2 @entity1 undergoing total colectomy. During follow-up, @entity1964 occurred in 11 cases(3.8%), including healing in 8 cases with conservative therapy, death in 1 case, and recurrent attacks in 2 cases. Soiling occurred in 45 cases(15.7%), among them, 5 cases presented in kindergarten and primary school. Morbidities of perianal @entity2681 , @entity1964 and soiling were higher in @entity1 undergoing operation within 3 months as compared to those more than 3 months [90.7%(49/63) vs. 6.0%(14/63), P=0.000; 9.3%(5/54) vs. 2.6%(6/232), P=0.022; 25.9%(14/54) vs. 13.4%(31/232), P=0.022]. Morbidity of perianal @entity1964 was higher in @entity1 undergoing subtotal or total colectomy as compared to those partial colon resection[51.9%(14/27) vs. 18.9%(49/259), P=0.000; 18.5%(5/27) vs. 2.3%(6/259), P=0.000]. CONCLUSIONS: Primary transanal endorental pull-through procedure can be performed in most @entity1 with @entity1963 . Postoperative short-term complications are mainly perianal @entity2681 and long-term ones are @entity1964 and soiling. Early diagnosis, colon irrigation, avoiding premature operation and anal dilation can decrease the morbidities of @entity1964 and soiling.

[Complication analysis of endorectal pull-through radical operation for XXXX ].

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'infants'] @entity2681 :: ('MESH:D014077', 'Disease') :: ['erosion'] @entity384 :: ('MESH:D002311', 'Disease') :: ['anus dilation'] @entity1963 :: ('MESH:D006627', 'Disease') :: ['Hirschsprung disease'] @entity6204 :: ('MESH:D000694', 'Disease') :: ['Perianal erosion'] @entity1964 :: ('MESH:D004760', 'Disease') :: ['erosion enterocolitis', 'enterocolitis'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation']
@entity1963 :: (MESH:D006627,Disease) :: ['Hirschsprung disease']
