Adverse reactions to food, i.e. @entity5419 and intolerance have gained considerable attention. This overview focuses on the diagnosis and management of IgE-mediated @entity5419 that is believed to be responsible for most immediate-type food-induced @entity56 reactions. Clinically, these reactions are characterised by a variety of signs and symptoms that occur within minutes or hours after consumption of the offending food. Reactions may be limited or more generalised with involvement of the skin, nose, eyes, and/or lungs. In more severe cases, cardiovascular symptoms including @entity551 , @entity1457 , @entity943 and @entity204 can occur. In food- @entity56 individuals, IgE is produced against naturally occurring food components, primarily glycoproteins that usually retain their allergenicity after heating and/or proteolysis. While adults tend to be @entity56 to fish, crustaceans, peanuts and tree nuts, @entity1 tend to be @entity56 to @entity291 's milk, egg white, @entity3505 and soy more frequently. "Emerging" food allergens include tropical fruits, @entity5420 seeds, psyllium, spices and condiments. These @entity566 frequently represent a cross- @entity566 to an allergen derived from another source, e.g. pollens or natural rubber latex. The evaluation of IgE-mediated @entity5419 relies on a careful history, physical examination, appropriate skin testing or in vitro testing with food extracts, and/or double blind, placebo-controlled food challenges. Avoidance remains the mainstay of therapy. However, allergens may be "hidden" and labelling can be non-precise or misleading, thereby severely hampering prevention. @entity1 with severe @entity566 should keep at hand an emergency kit with @entity1425 , an @entity16206 and an injectable rapid onset-of-action corticosteroid. At present there is no evidence to support the use of immunotherapy, except for research purposes. Production of "hypoallergenic" food is hampered by incomplete methods for assessing the allergenic potential of such novel foods.

IgE-mediated XXXX --extensive review of the literature.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients'] @entity16206 :: ('CHEBI:37956', 'Chemical') :: ['antihistamine'] @entity943 :: ('MESH:D001145', 'Disease') :: ['cardiac dysrhythmias'] @entity5419 :: ('MESH:D005512', 'Disease') :: ['food allergy'] @entity1457 :: ('MESH:D012769', 'Disease') :: ['shock'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergy', 'allergies'] @entity1425 :: ('MESH:D004837', 'Chemical') :: ['adrenaline'] @entity56 :: ('MESH:D004342', 'Disease') :: ['allergic', 'hypersensitivity'] @entity3505 :: ('4565', 'Species') :: ['wheat'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity291 :: ('9913', 'Species') :: ['cow'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity5420 :: ('4182', 'Species') :: ['sesame']
@entity5419 :: (MESH:D005512,Disease) :: ['food allergy']
