This study examined the prevalence of highly and minimally leukotoxic @entity3841 in @entity1 with @entity2520 . @entity33955 samples from 136 @entity1 with some form of @entity2520 were examined. Subjects were between 14 and 76 years of age. Clinical examinations included @entity6885 ( @entity5951 ), plaque index (PI) and bleeding index (BI). The obtained plaque samples were examined for the presence of highly or minimally leukotoxic A. actinomycetemcomitans strains by the polymerase chain reaction (PCR). Chi-square and logistic regression were performed to evaluate the results. Forty-seven subjects were diagnosed with @entity2522 , 70 with @entity7278 and 19 with aggressive @entity2521 . According to chi-square there was no significant correlation detected between @entity5951 (chi2 = 0.73), PI (chi2 = 0.35), BI (chi2 = 0.09) and the presence of the highly leukotoxic A. actinomycetemcomitans. The highly leukotoxic A. actinomycetemcomitans strains were correlated with subjects that were 28 years of age and younger (chi2 = 7.41). There was a significant correlation between highly leukotoxic A. actinomycetemcomitans and aggressive @entity2521 (chi2 = 22.06). This study of a Brazilian cohort confirms the strong association between highly leukotoxic A. actinomycetemcomitans strains and the presence of aggressive @entity2521 .

Detection of highly and minimally leukotoxic XXXX strains in @entity1 with @entity2520 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2520 :: ('MESH:D010510', 'Disease') :: ['periodontal disease'] @entity6885 :: ('MESH:D010514', 'Disease') :: ['periodontal pocket depth'] @entity7278 :: ('MESH:D055113', 'Disease') :: ['chronic periodontitis'] @entity2522 :: ('MESH:D005891', 'Disease') :: ['gingivitis'] @entity3841 :: ('714', 'Species') :: ['Actinobacillus actinomycetemcomitans'] @entity2521 :: ('MESH:D010518', 'Disease') :: ['periodontitis'] @entity33955 :: ('MESH:D010981', 'Disease') :: ['Pooled subgingival plaque'] @entity5951 :: ('MESH:D005888', 'Disease') :: ['PD']
@entity3841 :: (714,Species) :: ['Actinobacillus actinomycetemcomitans']
