UNASSIGNED: @entity6981 ( @entity6981 ) is the leading cause of vaginal discharge and is associated with the facultative Gram-variable bacterium @entity8439 , whose population structure consists of four clades. Our goal was to determine if these clades differ with regard to abundance during @entity6981 . We performed a short-term longitudinal study of @entity6981 . @entity1 were evaluated according to the @entity36525 criteria and Nugent scoring at initial diagnosis, immediately after treatment and at a 40- to 45-day follow-up visit. @entity8439 clade abundance was determined by quantitative real-time polymerase chain reactions (qPCRs). Among all specimens, the abundance of clades 1 and 4 were higher than that of clades 2 and 3 (P   <   0.001). In general, the abundance of each clade increased with the degree of @entity6636 , as determined by the Nugent score and was greater in @entity1 with @entity36525 4 compared with those with @entity36525 0. Only clade 1 abundance was greater when @entity36525 0 or 1 specimens were compared with @entity36525 2 or 3 specimens (P   <   0.01). Following antimicrobial treatment, abundance of clades 1 (P   <   0.001) and 4 (P   <   0.05) decreased regardless of the clinical and microbiological outcome, whereas clade 2 only decreased in @entity1 who had a sustained treatment response for 40-45  days (P   <   0.01). Recurrent @entity6981 was characterized by post-treatment increases of clade 1 and 2 (P   <   0.01). Clades 1 and 4 predominate in vaginal specimens. Clade abundance differs with regard to the Nugent score, the @entity36525 criteria, and response to therapy and @entity6981 recurrence.

XXXX population dynamics in @entity6981 .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients'] @entity8439 :: ('2702', 'Species') :: ['G. vaginalis', 'Gardnerella vaginalis'] @entity6636 :: ('MESH:D064806', 'Disease') :: ['vaginal dysbiosis'] @entity6981 :: ('MESH:D016585', 'Disease') :: ['Bacterial vaginosis', 'BV'] @entity36525 :: ('9187', 'Species') :: ['Amsel']
@entity8439 :: (2702,Species) :: ['Gardnerella vaginalis']
