BACKGROUND: A 44-year-old @entity1 presented with intermittent macroscopic @entity811 on a background of chronic left-sided @entity3041 and intestinal metaplasia of the bladder. Cystoscopic examination revealed a mass at the dome of the urinary bladder, which was resected. Histopathologic analysis of the specimen confirmed the presence of muscle-invasive @entity420 . Radical cystectomy with curative intent was planned, but review of systems and subsequent CT demonstrated @entity1143 with positive cytology, confirming @entity3 . Owing to the histologic similarity between this @entity1 's @entity5 and @entity14 , palliative FOLFOX6 ( @entity4181 , @entity1487 and @entity901 ) chemotherapy plus bevacizumab was administered. After 3 months of treatment the @entity1 showed a good response, which was sustained for more than 10 months after diagnosis. However, his disease subsequently relapsed, and the @entity1 died shortly thereafter. INVESTIGATION: Physical examination, cystoscopy, transurethral resection of bladder tissue, CT, histopathologic, cytopathologic and immunohistochemical analysis. DIAGNOSIS: Metastatic @entity1494 . MANAGEMENT: 12 cycles of infused and bolus @entity1487 , @entity4181 and @entity901 (FOLFOX6) plus bevacizumab.

Sustained response of XXXX to FOLFOX plus bevacizumab.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity1143 :: ('MESH:D010996', 'Disease') :: ['pleural effusion'] @entity4181 :: ('MESH:D002955', 'Chemical') :: ['folinic acid'] @entity901 :: ('MESH:C030110', 'Chemical') :: ['oxaliplatin'] @entity1494 :: ('MESH:D001745', 'Disease') :: ['adenocarcinoma of the urinary bladder'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity3041 :: ('MESH:D006869', 'Disease') :: ['hydronephrosis'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic disease'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity811 :: ('MESH:D006417', 'Disease') :: ['hematuria'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-fluorouracil']
@entity1494 :: (MESH:D001745,Disease) :: ['adenocarcinoma of the urinary bladder']
