INTRODUCTION: Bleeding ectopic small bowel varices pose a clinical dilemma for the physician, given their diagnostic obscurity and the lack of evidence-based medicine to guide therapy. They often occur in the context of @entity101 , secondary to either @entity409 or extrahepatic causes. Rarely is their presence associated with chronic superior @entity715 and @entity3459 . CASE PRESENTATION: A 74-year-old white @entity1 , with a heterozygous @entity5337 mutation and no underlying @entity409 or @entity101 , presented over the course of 13 months for recurrent episodes of @entity476 and per @entity548 . An initial endoscopy showed a clean-based chronic gastric ulcer, while colonoscopies showed multiple, non- @entity548 angioectasias which were treated with @entity3503 plasma coagulation. Subsequent video capsule endoscopy and double balloon enteroscopy revealed red wale marks overlying engorged submucosal veins in her distal ileum, consistent with ectopic varices. A chronic superior mesenteric vein thrombus, found via computed tomography venogram, was the cause of the ileal varices. She underwent curative surgical resection of the affected bowel, with no re- @entity548 episodes 17 months post-surgery, despite needing lifelong anticoagulation for recurrent @entity1211 . CONCLUSIONS: Clinicians should consider ectopic varices in @entity1 who present with obscure @entity360 , even in the absence of @entity101 or @entity409 . In those with a known @entity49 , @entity1 should be screened for @entity715 , which may precipitate ectopic varices.

Small bowel varices secondary to chronic superior @entity715 in a XXXX with heterozygous @entity5337 mutation: a case report.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients'] @entity5337 :: ('2153', 'Gene') :: ['Factor V Leiden'] @entity101 :: ('MESH:D006973', 'Disease') :: ['portal hypertension'] @entity548 :: ('MESH:D006470', 'Disease') :: ['rectal bleeding', 'bleeding'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver disease'] @entity49 :: ('MESH:D019851', 'Disease') :: ['thrombophilia'] @entity476 :: ('MESH:D008551', 'Disease') :: ['melena'] @entity3459 :: ('MESH:D025861', 'Disease') :: ['hereditary coagulopathies'] @entity715 :: ('MESH:D013927', 'Disease') :: ['splanchnic thrombosis', 'mesenteric vein thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thromboembolisms'] @entity360 :: ('MESH:D006471', 'Disease') :: ['gastrointestinal bleeding'] @entity3503 :: ('MESH:D001128', 'Chemical') :: ['argon']
@entity1 :: (9606,Species) :: ['patient']
