@entity1581 are frequently seen in B-cell @entity5 . Monoclonal proteins are seen in a significant proportion of @entity1 with @entity1072 ( @entity1072 ), which is a clonal disorder of mature B cells. The use of more sensitive laboratory methods has enabled the detection of monoclonal proteins or light chains in the serum and/or urine in the majority of these @entity1 . The presence of some of these monoclonal proteins may explain the different autoimmune phenomena that are associated with this disease. Some reports indicate that the finding of monoclonal proteins has a negative impact on @entity1 ' survival. The presence of two different monoclonal proteins (i.e. @entity1581 ) is on the other hand rare. Most of the reported cases in the literature are of @entity1 with plasma cell disorders. In this report, we describe a rare occurrence of @entity1581 in a @entity1 with @entity1072 . Serum protein electrophoresis and immunofixation, which were negative at the time of initial diagnosis, showed biclonal immunoglobin A (IgA) kappa and IgA lambda during the course of the disease. The @entity1 's disease showed steady progression, despite multiple treatments. Although this could just be the result of using more sensitive laboratory techniques, @entity1581 in this @entity1 likely reflects the evolution of another clone, which would explain the encountered resistance to therapy. Because of paucity of reports, the impact of @entity1581 in such @entity1 is not known and an effort to collectively report the presentation and outcome of these @entity1 is needed to further understand the pathophysiology and clinical significance of such a finding.

XXXX in @entity1072 : Case Report and Review of the Literature.

@entity5 :: ('MESH:D009369', 'Disease') :: ['malignancies'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1072 :: ('MESH:D015451', 'Disease') :: ['CLL', 'chronic lymphocytic leukemia'] @entity1581 :: ('MESH:D010265', 'Disease') :: ['biclonal gammopathy', 'Monoclonal gammopathies', 'biclonal gammopathies']
@entity1581 :: (MESH:D010265,Disease) :: ['Biclonal Gammopathy']
