OBJECTIVES: Although @entity3458 is the most common of all @entity74 , there are a few publications about the effects of the disease on the functions of the ears, nose and throat. In this review, we present an overview of the clinical manifestations of @entity3458 in general and highlight the problems specifically presenting in the field of otorhinolaryngology. METHODS: We review the pathophysiology of @entity3458 and its clinical features in general. Then, we review its manifestations in ear, nose and @entity66 . CONCLUSION: Sickle cell disease is one of the most common @entity8453 . It can cause severe @entity158 crises and dysfunction of virtually every organ system in the body, ultimately causing @entity204 . There is high prevalence (55%) of obstructive @entity1184 in @entity1 and adolescents with @entity3458 . A very significant reduction has been observed in the rate of @entity158 crises following tonsillectomy in @entity1 with @entity417 . Prevalence rate for @entity1274 in older @entity1 and adult @entity1 is reporting a range of 11-41%. @entity3327 of the turbinates is a cause of nasal obstruction in @entity417 which needs partial turbinectomy. @entity4585 should be considered in the differential diagnosis of any paranasal sinus mass presenting in a @entity1 with known chronic @entity417 .

Otorhinolaryngological manifestations of XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['throat diseases'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anaemia', 'sickle cell anaemia'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['adenotonsillar hypertrophy'] @entity3458 :: ('MESH:D000755', 'Disease') :: ['sickle cell disease'] @entity3327 :: ('MESH:D011317', 'Disease') :: ['Priapism'] @entity1274 :: ('MESH:D006319', 'Disease') :: ['sensorineural hearing loss'] @entity8453 :: ('MESH:D006453', 'Disease') :: ['hemoglobinopathies'] @entity74 :: ('MESH:D030342', 'Disease') :: ['hereditary disorders'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity204 :: ('MESH:D003643', 'Disease') :: ['premature death'] @entity4585 :: ('MESH:D023981', 'Disease') :: ['Extramedullary haematopoiesis']
@entity3458 :: (MESH:D000755,Disease) :: ['sickle cell disease']
