BACKGROUND: As diagnosis and treatment of unruptured @entity438 continues to increase, management principles remain largely based on size. This is despite mounting evidence that @entity439 location and other morphologic variables could play a role in predicting overall risk of @entity397 . Morphological parameters can be divided into 3 main groups, those that are intrinsic to the @entity439 , those that are extrinsic to the @entity439 , and those that involve both the @entity439 and surrounding vasculature (transitional). OBJECTIVE: We present an evaluation of intrinsic, transitional, and extrinsic factors and their association with @entity1756 . METHODS: Using preoperative computed tomographic angiography, we generated 3-dimensional models of @entity439 and their surrounding vasculature with Slicer software. Using univariate and multivariate analyses, we examined the association of intrinsic, transitional, and extrinsic aspects of @entity439 morphology with @entity397 . RESULTS: Between 2005 and 2013, 227 @entity438 in 4 locations were evaluated/treated at a single institution, and computed tomographic angiographies of 218 @entity1 (97 unruptured and 130 ruptured) were analyzed. @entity1756 analyzed were associated with clinical factors of absence of @entity439 and history of no prior @entity397 , and morphologic factors of greater aspect ratio. On multivariate analysis, @entity1756 remained associated with history of no prior @entity397 , greater flow angle, greater daughter-daughter vessel angle, and smaller parent-daughter vessel angle. CONCLUSION: By studying the morphology of @entity439 and their surrounding vasculature, we identified several parameters associated with @entity1756 that include intrinsic, transitional, and extrinsic factors of @entity438 and their surrounding vasculature.

Intrinsic, Transitional, and Extrinsic Morphological Factors Associated With XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity438 :: ('MESH:D002532', 'Disease') :: ['cerebral aneurysms', 'intracranial aneurysms'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms', 'aneurysm', 'multiple aneurysms'] @entity1756 :: ('MESH:D017542', 'Disease') :: ['Ruptured aneurysms', 'ruptured aneurysms', 'aneurysm rupture']
@entity1756 :: (MESH:D017542,Disease) :: ['Rupture of Intracranial Aneurysms']
