OBJECTIVE: We sought to compare @entity339 and replacement as treatments for @entity179 with coexisting @entity741 . Specifically, we sought to (1) identify differences between @entity1 undergoing repair and replacement, (2) determine whether the choice of mitral valve procedure affected survival after adjusting for those differences, and (3) discover which @entity1 were predicted to benefit from @entity339 and which from replacement. METHODS: From 1973 to 1999, 679 @entity1 (mean age, 67 +/- 9.1 years; 73% @entity1 ) with @entity339 and @entity741 underwent combined coronary artery bypass grafting and either @entity339 (66%) or replacement (34%). Factors associated with repair and replacement were used for multivariable propensity matching. Risk factors for @entity204 were identified by means of multivariable, multiphase hazard-function analysis. RESULTS: @entity1 more likely to undergo repair had isolated posterior @entity397 (P <.0001) or more recent date of operation (P <.0001); those more likely to undergo replacement were older (P =.0003) or had bileaflet prolapse (P <.0001). Unadjusted survival at 30 days and 1, 5, and 10 years was 97%, 92%, 79%, and 59% after repair and 94%, 88%, 70%, and 37% after replacement. After adjusting for comorbid factors, the extent and effect of @entity741 , and propensity score, the survival benefit of repair became evident after 2 years (P =.01). Eighty-nine percent of @entity1 were predicted to benefit from repair. CONCLUSIONS: In @entity1 with @entity339 and @entity741 , @entity339 confers a survival advantage over replacement that becomes evident about 2 years after the operation.

Repair versus replacement for XXXX with coexisting @entity741 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity339 :: ('MESH:D008944', 'Disease') :: ['degenerative mitral valve', 'mitral valve repair'] @entity397 :: ('MESH:D012421', 'Disease') :: ['chordal rupture'] @entity179 :: ('MESH:D019636', 'Disease') :: ['degenerative mitral valve disease'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease', 'ischemic heart diseases'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity179 :: (MESH:D019636,Disease) :: ['degenerative mitral valve disease']
