OBJECTIVE: To investigate the efficacy of a perioperative oral @entity479 taper on @entity4365 after cochlear implantation. STUDY DESIGN: Retrospective case series. SETTING: Tertiary referral center. @entity1 : Consecutive cochlear implant recipients between January 2012 and December 2014 who were candidates for a hearing preservation approach based on preoperative pure tone thresholds were identified. INTERVENTIONS: A subgroup of @entity1 received a 2-week oral corticosteroid taper beginning 3 days before surgery. All @entity1 were implanted using standard length electrodes. MAIN OUTCOME MEASURES: The preservation of low-frequency pure tone thresholds on the first postoperative audiogram was assessed. Secondary outcome measures included the respective impacts of age, @entity6 , and electrode array type on hearing preservation, the durability of hearing preservation over time, and the development of medical complications related to @entity479 use. RESULTS: Twenty-seven ears met inclusion criterion, and the mean age at implantation was 49.8 years (median 62 yr, range 2-81 yr). Twenty @entity1 (74.1%, mean age 48.7 yr) received an oral corticosteroid taper, whereas 7 (25.9%, mean age 53.1 yr) did not. The rate (p<0.01) and degree (p<0.01) of hearing preservation as measured at implant activation was greater for @entity1 who received an oral @entity479 taper than those who did not. There were no medical complications related to @entity479 use. CONCLUSION: A 2-week oral @entity229 taper beginning before surgery may positively affect the incidence and degree of @entity4365 after cochlear implantation.

Impact of Perioperative Oral XXXX Use on Low-frequency Hearing Preservation After Cochlear Implantation.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity4365 :: ('MESH:C565121', 'Disease') :: ['low-frequency hearing preservation'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity479 :: (D013256,Chemical) :: ['Steroid']
