AIM: To determine any change in T-lymphocyte subsets after applying different treatment methods in smokers and non-smokers with @entity7278 . @entity1 : 50 adults with @entity7278 . METHOD: The subjects were divided into smokers and non-smokers. Biopsy samples were taken from the gingival pocket wall tissues at sites with @entity7278 before treatment, after initial treatment, after curettage and after flap operation and tested for @entity404 +, @entity405 + lymphocyte and @entity404 / @entity405 ratio values. @entity5951 depth, gingival index (GI-L  e-Silness) and plaque index (PI-Silness-L  e) scores were also recorded. Analysis aimed at determining the relation between the clinical measurements and the laboratory results. RESULTS: Flow cytometry findings in both groups showed that @entity404 + and @entity405 + lymphocyte values before treatment were under the normal value while the @entity404 +/ @entity405 + ratio was within normal distribution interval. The lymphocyte values observed in the smokers were found to be lower than those in the non-smokers. After treatment the difference between the lymphocyte values in smokers and non-smokers was found to be statistically significant. However, the difference between the @entity404 / @entity405 rate obtained in smokers and non-smokers was not found to be statistically significant. CONCLUSIONS: The lymphocyte values observed in smokers were found to be lower than those in non-smokers after applying different treatment methods and the local immune response was poor in the smokers.

Flow-cytometric analysis of T-lymphocyte subsets after different treatment methods in smokers and non-smokers with XXXX .

@entity1 :: ('9606', 'Species') :: ['PARTICIPANTS'] @entity404 :: ('920', 'Gene') :: ['CD4'] @entity7278 :: ('MESH:D055113', 'Disease') :: ['chronic periodontitis'] @entity405 :: ('925', 'Gene') :: ['CD8'] @entity5951 :: ('MESH:D005888', 'Disease') :: ['Gingival pocket']
@entity7278 :: (MESH:D055113,Disease) :: ['chronic periodontitis']
