BACKGROUND: This study characterized the infiltration of @entity5 along the intrinsic and extrinsic muscles of the tongue in @entity957 ( @entity957 ), to create a new surgical strategy that is suitable for most stages. A preliminary evaluation of this novel surgical approach was also conducted. METHODS: An anatomic study of macroscopic specimens from 10 @entity1 cadavers and 100 @entity957 @entity1 was conducted. The anatomic characteristics of the @entity5 and the origin and distribution of fibers of the @entity121 were observed and measured. After initial treatment with curative intent, the 100 @entity1 were regularly followed-up with clinical examination and imaging. RESULT: Based on the anatomic characteristics of the @entity5 and tongue muscles, a new surgical approach was developed, and was described as muscle anatomy tongue surgery (MATS). MATS proved suitable for almost all stages of @entity957 . According to the morphology of the invasive @entity5 front, the 100 cases were divided into four types. The rate of 2-year local disease control was 98%, locoregional control 86%, disease-free survival 85%, and overall survival 89%. Tongue functions were perfectly recovered in more than 60% of the @entity1 . CONCLUSION: Application of the principles of MATS to the treatment of @entity957 proved suitable for almost all stages of the disease. MATS is a novel surgical technique that may improve outcomes in @entity5 surgery.

A new surgical strategy for treatment of XXXX based on anatomic study with preliminary clinical evaluation.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumors', 'tongue cancer'] @entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity957 :: ('MESH:D002294', 'Disease') :: ['OTSCC', 'oral tongue squamous cell carcinoma'] @entity121 :: ('MESH:D009135', 'Disease') :: ['intrinsic and extrinsic tongue muscles']
@entity957 :: (MESH:D002294,Disease) :: ['tongue squamous cell carcinoma']
