BACKGROUND: It is well-recognized that @entity6 represents a powerful independent risk factor for @entity65 . However, very few studies have investigated the relationship between @entity6 and risk of @entity1580 ( @entity1580 ). AIM: The aim of this case-control study was to evaluate the association between @entity6 and risk of @entity1580 in Chinese population. METHODS: A hospital-based case-control study, consisting of 2160 @entity1580 @entity1 and 4320 controls, was conducted in a Chinese population. Demographic, clinical characteristics and risk factors were collected. @entity6 rate of @entity1 with overall @entity1580 , Stanford type A @entity1580 and type B @entity1580 group was compared with that of corresponding matched control groups. Logistic regression analysis was used to estimate the odds ratios (OR) and 95% confidence intervals (95% CI) for relationship between @entity6 and @entity1580 risk. RESULTS: The prevalence of @entity6 was lower in @entity1580 cases than that of control subjects, whether it is the overall @entity1580 , type A @entity1580 or type B @entity1580 group (4.7% vs. 10.0%, 2.9% vs. 8.8%, 5.9% vs. 10.9%, all P<0.001). Furthermore, in multivariate model, @entity6 was found to be associated with lower @entity1580 risk, which not only applies to the overall @entity1580 (OR = 0.2, 95%CI: 0.15-0.26), but also type A @entity1580 (OR = 0.12, 95% CI: 0.07-0.20) and type B @entity1580 (OR = 0.25, 95%CI: 0.18-0.33). CONCLUSIONS: We observed the paradoxical inverse relationship between @entity3918 and risk of @entity1580 in the Chinese population. These results suggest @entity6 may play a protective role in the development of @entity1580 . However, further studies are needed to enrich related evidence, especially with regard to underlying mechanisms for these trends.

Association between XXXX and Risk of Aortic Dissection: A Case-Control Study in a Chinese Population.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'diabetes'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular diseases'] @entity3918 :: ('MESH:D009223', 'Disease') :: ['DM'] @entity1580 :: ('MESH:C562834', 'Disease') :: ['aortic dissection', 'AD']
@entity6 :: (MESH:D003920,Disease) :: ['Diabetes']
