OBJECTIVE: To evaluate gender differences in score on 28-joint Disease Activity Score (DAS28), Health Assessment Questionnaire (HAQ) and Signals Of Functional Impairment (SOFI) and to relate these scores to @entity2720 . METHODS: In all, 549 @entity1 with early @entity309 (62% @entity1 ) from the BARFOT (for "Better Anti-Rheumatic FarmacOTherapy") study were included. At baseline, 1, 2 and 5 years DAS28, HAQ and SOFI scoring, and radiographs of hands and feet were performed. The radiographs were scored using the van der Heijde-Sharp score. RESULTS: In @entity1 the DAS28 was significantly higher than in @entity1 due to higher scores for general health and @entity2720 . Likewise, HAQ and @entity158 were rated significantly higher in @entity1 . The SOFI score was worse in @entity1 during the first 2 years, depending on higher upper limb scores. Total Sharp score (TotSharp), erosion score and joint space narrowing score did not differ between the sexes at any time point. The DAS28 area under the curve (AUC) correlated significantly with TotSharp at 5 years in both genders (r = 0.316, r = 0.313) mainly owing to swollen joints and erythrocyte sedimentation rate (ESR). The SOFI AUC correlated significantly with TotSharp in @entity1 (r = 0.135 to 0.220) but not in @entity1 . CONCLUSIONS: Despite a similar degree of @entity2720 @entity1 had, compared with @entity1 , worse scores for DAS28 and HAQ, possibly due to higher @entity158 perception and less muscular strength and perhaps because @entity1 overestimate their functional capacity.

Influence of gender on assessments of disease activity and function in early XXXX in relation to radiographic joint damage.

@entity2720 :: ('MESH:D007592', 'Disease') :: ['tender joints', 'radiographic joint destruction'] @entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity309 :: ('MESH:D001172', 'Disease') :: ['RA'] @entity158 :: ('MESH:D010146', 'Disease') :: ['VAS pain', 'pain']
@entity309 :: (MESH:D001172,Disease) :: ['rheumatoid arthritis']
