OBJECTIVE: @entity581 were introduced into use over 60 years ago. The University Hospital of the West Indies (UHWI), a tertiary care teaching hospital, in Kingston, Jamaica, introduced the use of @entity801 in 1973 and @entity4509 in 1980. This report examined the susceptibility patterns to these agents in 1547 consecutive isolates of @entity6281 ( @entity6281 ) encountered between September 1 and November 30, 2011, at UHWI and compares the data with those observed previously in 1981 at the same institution. METHODS: The Vitek 2 (bioMeri  ux, Durham, NC) was used for isolate identification, minimum inhibitory concentration determination and @entity5292 susceptibility testing. Quality control was done using American Type Culture Collection standard strains of @entity526 (ATCC 25922) and @entity796 (ATCC 27853). RESULTS: Of the 1547 organisms, 267 had resistance to one or both @entity581 . @entity4509 resistance increased from 0.6% (1981) to 7.2% [2011] (p < 0.05), while @entity801 resistance increased from 6.7% to 14.8% (p < 0.05) for the corresponding period. The majority of samples with @entity5292 resistant organisms came from the intensive care unit and surgical inpatients. Urine samples persistently produced the largest amount of @entity801 resistant isolates. CONCLUSIONS: Although there has been a statistically significant rise in @entity5292 resistance, @entity581 continue to remain highly effective against approximately 83% of @entity6281 despite continuous usage at this institution for over three decades. Continued national surveillance, implementation of infection control policies and antibiotic stewardship are all essential in retaining low resistance levels.

XXXX Resistance in Clinical Isolates of Gram Negative Bacilli at the University Hospital of the West Indies, Jamaica: Comparison of Two Time Periods.

@entity801 :: ('MESH:D005839', 'Chemical') :: ['gentamicin'] @entity796 :: ('287', 'Species') :: ['Pseudomonas aeruginosa'] @entity4509 :: ('MESH:D000583', 'Chemical') :: ['amikacin', 'Amikacin'] @entity5292 :: ('D000617', 'Chemical') :: ['aminoglycoside'] @entity6281 :: ('MESH:D016905', 'Disease') :: ['Gram negative bacilli', 'GNB'] @entity581 :: ('MESH:D000617', 'Chemical') :: ['Aminoglycosides', 'aminoglycosides'] @entity526 :: ('562', 'Species') :: ['E coli']
@entity5292 :: (D000617,Chemical) :: ['Aminoglycoside']
