PURPOSE: Primary @entity706 (PTL) is a rare disease and it has been investigated in a limited number of studies. The present multicenter study evaluated the clinical features and treatment outcomes of PTL. METHODS: The medical records of @entity1 diagnosed with PTL between 2000 and 2013 in three centers were retrospectively reviewed. RESULTS: The study included 11 @entity1 and 27 @entity1 with a median age of 63.3 years (range, 42-83 years). The median follow-up was 56.0 months (range, 3-156 months). Of the 38 @entity1 included, 16 had @entity1074 ( @entity1074 ) @entity706 , six had mixed @entity1074 and @entity1892 ( @entity1892 ), and 16 had @entity1892 . Thirty-five @entity1 (92.1%) had early stage (stage I/II) disease. Of the 16 @entity1074 @entity1 , 14 were treated by surgery, and radiotherapy (RT) or chemotherapy was combined in five @entity1 . Two @entity1 received RT or chemotherapy alone. Of the six mixed @entity1074 and @entity1892 @entity1 , three underwent surgery with chemotherapy and three underwent chemotherapy alone, RT alone, or surgery with RT. All of the 16 @entity1892 @entity1 received chemotherapy, and surgery and RT was combined in 4 and 1 @entity1 , respectively. The 5-year survival was 100% for @entity1074 (7 of 7) and mixed @entity1074 and @entity1892 @entity1 (5 of 5) and 87.5% for @entity1892 @entity1 (7 of 8). CONCLUSION: Early stage PTL has an excellent prognosis when managed by single or combined treatment modalities. Clinicians should consider PTL in @entity1 with underlying @entity2621 presenting with an enlarging @entity1374 .

Clinicopathological characteristics and treatment outcomes of 38 cases of primary XXXX : a multicenter study.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma', 'thyroid lymphoma'] @entity2621 :: ('MESH:D050031', 'Disease') :: ["Hashimoto's thyroiditis"] @entity1074 :: ('MESH:D018442', 'Disease') :: ['MALT lymphoma', 'MALT', 'mucosa-associated lymphoid tissue'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['DLBCL', 'diffuse large B-cell lymphoma'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroid mass']
@entity706 :: (MESH:D008223,Disease) :: ['thyroid lymphoma']
