SCOPE: Low-grade chronic @entity32 is associated with several chronic conditions, and diet is known to play a role in chronic @entity32 . We aimed to evaluate the association between the inflammatory potential of the diet and mortality in the Spanish population from the European Prospective Investigation into @entity5 and Nutrition (EPIC-Spain). METHODS AND RESULTS: The study included 41199 @entity1 (62% female) aged 29-69 years from 5 Spanish regions. During 18 years of follow-up 3316 @entity204 were identified. The dietary inflammatory potential was assessed by means of an @entity32 ( @entity32 ), calculated using 30 dietetic components and their corresponding inflammatory scores (weights). The association between the @entity32 and mortality was analyzed by multivariate Cox regression models. There was a significant association between @entity32 and mortality: subjects classified in the fifth quintile of the @entity32 (more pro-inflammatory diets) had a hazard ratio of 1.42 (95%-confidence interval 1.25-1.60) as compared with those in the first quintile; the corresponding figures were 1.89 (1.48-2.40) for @entity65 mortality and 1.44 (1.22-1.69) for @entity204 by @entity5 ). CONCLUSION: Consuming more pro-inflammatory diets, expressed by means of the @entity32 , is associated with higher mortality; this effect seems to be stronger for @entity204 by @entity65 . This article is protected by copyright. All rights reserved.

Inflammatory potential of the diet and mortality in the Spanish cohort of the European Prospective Investigation into XXXX and Nutrition (EPIC-Spain).

@entity1 :: ('9606', 'Species') :: ['participants'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammatory score of the diet', 'inflammation', 'ISD'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'Cancer'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'deaths'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular diseases']
@entity5 :: (MESH:D009369,Disease) :: ['Cancer']
