Thyroid heterotopic bone formation (HBF) in @entity5651 is a rare finding. Five thyroid resection specimens were analyzed for HBF. The results were correlated with clinicomorphological features. All @entity1 were @entity1 (33-82 years). The preoperative diagnosis was @entity5651 or nodule. Treatment consisted in thyroidectomy and lobectomy (3 and 2, resp.). Microscopy showed sporadic @entity8170 . @entity729 were seen in intra- and extrathyroid location (5 and 3, resp.). The number and size of HBFs (total: 28) ranged between 1 and 23/thyroid gland (one bilateral) and 1 and 10   mm, respectively. Twelve HBFs were in contact with the thyroid capsule. Most were extranodular (21, versus 6 intranodular). The medical history was positive for @entity2299 , @entity4854 , @entity8 , and @entity5052 (2, 3, and 3 cases and 1 case, resp.) without any @entity8611 . In conclusion, thyroid HBF may be characterized by subcapsular or extranodular location, various size (usually >= 2   mm), and vascular @entity730 and @entity600 . Features of @entity209 and @entity8 may be present, but their exact role in the pathogenesis of HBFs remains to be elucidated.

Thyroid XXXX with Adult Heterotopic Bone Formation.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity8170 :: ('MESH:D006044', 'Disease') :: ['nodular goiter'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal dysfunction'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic syndrome'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity8611 :: ('MESH:D010279', 'Disease') :: ['parathyroid abnormality'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcifications'] @entity5651 :: ('MESH:D006042', 'Disease') :: ['goiter', 'thyroid goiter'] @entity5052 :: ('MESH:D033461', 'Disease') :: ['hyperuricemia'] @entity729 :: ('MESH:D061205', 'Disease') :: ['Malformative blood vessels and vascular calcifications'] @entity4854 :: ('MESH:D006943', 'Disease') :: ['hyperglycemia']
@entity5651 :: (MESH:D006042,Disease) :: ['Sporadic Goiter']
