BACKGROUND: Compound @entity308 have conventionally been managed surgically with elevation and debridement to avoid @entity281 , especially when there is dural penetration, nonetheless with little evidence. This study was to prospectively compare outcomes after simple suturing and elevation debridement in @entity1 with compound @entity308 . METHODS: @entity1 of compound @entity308 with GCS of five or more, no serious @entity1317 , and no significant mass effect were prospectively studied for various factors in relation to @entity281 , hospital stay, survival, and late post-traumatic @entity410 . Univariate and multivariate analyses were performed using SPSS21. RESULTS: Of the total 232 @entity1 with complete clinico-radiological and follow-up data, 183 underwent simple cleansing and suturing, and 49 underwent surgical elevation debridement. The surgical group at baseline had significantly lower GCS, greater dural violation, and @entity75 compared to the conservative arm. Univariate analysis showed simple suturing group to have significantly shorter hospital stay (2.4 vs. 10.3  days) (p   <   0.001), @entity281 among survivors (4 vs. 21  %) (p   =   0.001), and greater 'survival with no @entity281 ' (85 vs. 69  %) (p   =   0.01). Multivariate analysis adjusting for age, sex, GCS, dural penetration, and surgical intervention confirmed significantly shorter hospital stay (p   <   0.001) and @entity281 among survivors (p   =   0.02) in the simple suturing group. Overall, there was no benefit offered by surgical debridement. Simple suturing had a better outcome in most subgroups, except in those with @entity75 and GCS 5-8, which showed non-significant benefit with surgical intervention. CONCLUSIONS: Simple suturing seems to be an equally good option in @entity1 with compound @entity308 with no significant mass effect or @entity75 .

Prospective comparison of simple suturing and elevation debridement in compound XXXX with no significant mass effect.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressed fracture', 'depressed fractures'] @entity75 :: ('MESH:D001927', 'Disease') :: ['brain matter herniation'] @entity281 :: ('MESH:D007239', 'Disease') :: ['lesser infection', 'infection'] @entity1317 :: ('MESH:D057772', 'Disease') :: ['systemic injury']
@entity308 :: (MESH:D003866,Disease) :: ['depressed fractures']
