BACKGROUND: The use of permissive @entity551 includes a restrained volume preclinical therapy. However, in the elderly @entity1 , this approach has raised concerns because of the increased cardiovascular risk profile and a higher incidence of @entity101 under normal conditions. The aim of the study was to examine whether preclinical administration of restrictive volume therapy in the elderly @entity1 can be safe. @entity1 AND METHODS: A retrospective matched-pair analysis with the data set of the TraumaRegister DGU(  ) (TR-DGU) was performed based on data of 176 pairs of totally 67,000 @entity1 . To address elderly potentially @entity548 @entity1 without major @entity1545 the following inclusion criteria were chosen: @entity1 >= 60 years, ISS>= 16, @entity1984 head<4, preclinical blood pressure between 60 and 100mmHg and recorded preclinical volume administration. @entity1 that met the inclusion criteria (908) were divided into two groups: pre-clinical volume resuscitation  <=1000ml (=low volume) and >1000ml (high volume). @entity1 with high- and low-volume fluid replacement were matched according to the following criteria: age group, gender, date of the accident   5 years, ISS, GCS, preclinical intubation, ground-/air-transport, pre-clinical blood pressure. RESULTS: Preclinical volume resuscitation showed a difference of about 1000ml between the "low volume" and "high volume" group. The "low volume" group showed a significantly elongated prothrombin time. The amount of blood products given in the emergency department was not significantly different. The ventilation was 2 days shorter in the "low volume", although the number of @entity1 with severe @entity130 was greater in this group. The length of stay in the ICU differed by 3 days in favour of the "low volume" group. The overall mortality was almost the same in both groups. CONCLUSIONS: Based on these data it can be assumed that the lower preclinical volume administration has a positive effect on the @entity3459 status in elderly @entity1 . In spite of some limitations such as low number of matched pairs, we draw the cautious conclusion that a restrictive preclinical volume therapy is safe and also indicated in elderly @entity1 .

Limited volume resuscitation in XXXX elderly multiple trauma is safe and prevents early clinical dilutive coagulopathy - A matched pair analysis from TraumaRegister DGU(  ).

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'PATIENTS'] @entity1545 :: ('MESH:D020214', 'Disease') :: ['brain injury'] @entity1984 :: ('MESH:D013734', 'Disease') :: ['AIS'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity3459 :: ('MESH:D025861', 'Disease') :: ['initial coagulation'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity130 :: ('MESH:D014947', 'Disease') :: ['thoracic trauma']
@entity551 :: (MESH:D007022,Disease) :: ['hypotensive']
