INTRODUCTION: @entity1897 ( @entity1897 ) is an uncommon primary @entity99 that represents 10% of hepatic resections for primary @entity5 in our experience. @entity1 AND METHODS: From 1988 to 2004, 29 @entity1 with a diagnosis of @entity1897 were treated in our unit. One @entity1 was treated with chemoembolization and the remainder underwent surgery. In 7 @entity1 , hepatectomy was not performed due to the presence of an extrahepatic @entity5 or massive @entity99 . The resectability index was 75%. Twenty-one @entity1 underwent radical excision of @entity1897 and comprised the study group. RESULTS: The mean age was 60 years with a slight predominance of @entity1 . Sixty-two @entity1 were symptomatic and tumoral markers were elevated in 58%. @entity1897 developed in normal liver in 15 @entity1 , in cirrhotic liver in 2 @entity1 and in the context of chronic @entity99 in 4 @entity1 . The mean tumoral size was 7 cm (between 1.6 and 13 cm). @entity5 were found in 3 @entity1 , invasion of the hepatic hilum lymph nodes was found in 8 @entity1 and vascular invasion was observed in a further 8 @entity1 . Major hepatectomy was performed in 90% of the @entity1 ; radical lymphadenectomy of the hepatic hilum was performed in 15 @entity1 and excision of the extrahepatic biliary tract followed by Roux-en-Y hepaticojejunostomy in 4 @entity1 . Operative mortality occurred in 3 @entity1 (14%); one cirrhotic @entity1 died 4 days after surgery from cardiovascular causes and 2 @entity1 died from @entity1578 after extensive hepatectomies that included resection of the inferior vena cava and suprahepatic veins. Complications occurred in 33% of the @entity1 . Ten @entity1 (47%) died. Of these, 6 died from tumoral recurrence. Tumoral recurrence occurred in 9 @entity1 (5 hepatic and 4 extrahepatic). Hepatic recurrences were treated with radiofrequency ablation in 2 @entity1 and chemotherapy in 5 @entity1 . The median survival was 11 months. Actuarial survival at 1, 3 and 5 years was 60%, 47% and 47% respectively. Disease-free survival at 1, 3 and 5 years was 50%, 31% and 31% respectively. In univariate analysis, significant risk factors for mortality were @entity7453 and a resection margin of less than 1 cm. In multivariate analysis, negative factors for tumoral recurrence were @entity7453 , satellitosis, and poor tumoral delimitation. CONCLUSION: Surgical treatment of @entity1897 through radical hepatic resection with margins of more than 1 cm in @entity1 without nodal invasion provides good results with a 5-year survival of 79%.

[ XXXX : results of surgical treatment].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignant tumors', 'Multiple tumors'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['PC', 'Peripheral cholangiocarcinoma'] @entity1578 :: ('MESH:D017093', 'Disease') :: ['liver failure'] @entity7453 :: ('MESH:D008207', 'Disease') :: ['lymphatic invasion'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic invasion', 'hepatic tumor', 'hepatitis']
@entity1897 :: (MESH:D010523,Disease) :: ['Peripheral cholangiocarcinoma']
