AIMS: Histological restenosis models in animals have indicated that stent design has a significant impact on vessel @entity130 during stent implantation and on the amount of subsequent neointimal tissue proliferation. The impact of different stent designs on intimal @entity1373 in @entity1 @entity731 coronary arteries has not been determined. METHODS AND RESULTS: Angiographic and intravascular ultrasound studies were performed at the 6 month follow-up in 131 consecutive native coronary lesions of 131 @entity1 treated with 50 Multi-Link stents, 40 InFlow stents and 41 Palmaz-Schatz stents. Lumen and stent cross-sectional areas (CSA) were measured at 1 mm axial increments. Mean intimal @entity1373 cross-sectional area (stent CSA-lumen CSA) and mean intimal @entity1373 thickness were calculated. Intravascular ultrasound demonstrated different levels of intimal @entity1373 proliferation for the three stents. Mean intimal @entity1373 thickness was 0.16+/-0.08 mm for Multi-Link stents, 0.26+/-0.19 mm for Palmaz-Schatz stents and 0.39+/-0.14 mm for Inflow stents (P<0.001). Multivariate analysis proved that stent type was the only independent predictor of intimal @entity1373 thickness at follow-up (P<0.001). CONCLUSION: Coronary stent design has a significant impact on subsequent intimal @entity1373 after implantation into @entity731 @entity1 coronary arteries. The corrugated ring design of the Multi-Link stent proved to result in less tissue proliferation at 6-month follow-up than the tubular slotted design of Palmaz-Schatz and InFlow stents.

Stent design related neointimal tissue proliferation in XXXX coronary arteries; an intravascular ultrasound study.

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['hyperplasia'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity1 :: (9606,Species) :: ['human']
