@entity320 , also termed @entity14495 ( @entity14495 ), is a rare malignancy of neural crest origin which is different from @entity320 . Although a translocation involving chromosomes 12 and 22 is characteristic of @entity14495 and not @entity320 , there are a paucity of methods to differentiate the two. Therefore, a study of @entity124 ( @entity124 ) was undertaken to determine if mechanisms of DNA mismatch repair can differentiate these @entity5 . @entity124 has been described in a variety of @entity5 including 25% of @entity320 . @entity982 -embedded neoplastic and non-neoplastic cells were obtained from 11 individuals (five males; six females; age range from seven to 60 years) with @entity14495 . Isolated DNA was PCR amplified at 17 separate microsatellite loci using radioactive-labeled primers. @entity5 tissue was compared to normal tissue for each analysis. No @entity124 was detected. Loss of heterozygosity was detected in only one @entity1 at a single locus ( @entity686 ). The lack of @entity124 in @entity14495 further defines the distinction between this @entity5 and @entity320 . Clinically, local recurrence and @entity3 were indicators of poor outcome. The size of the @entity5 was not a significant prognostic indicator. Local recurrence, satellitosis, or nodal @entity3 was not proven to be uniformly fatal. Utilization of chemotherapy and/or radiation demonstrated no obvious survival advantage. The histologic parameters of mitotic rate and the presence of @entity39 were not prognostic. Limb-preserving surgical procedures were as effective as amputation for @entity66 control. The actuarial survival rate was calculated to be 48% at five years.

Clear cell sarcoma or XXXX : molecular analysis of @entity124 with clinical correlation.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity124 :: ('MESH:D053842', 'Disease') :: ['MIN', 'microsatellite instability'] @entity66 :: ('MESH:D004194', 'Disease') :: ['local disease'] @entity686 :: ('3438', 'Gene') :: ['IFNA'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumor', 'malignancies'] @entity982 :: ('MESH:D010232', 'Chemical') :: ['Paraffin'] @entity14495 :: ('MESH:D018227', 'Disease') :: ['clear cell sarcoma', 'CCS'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity320 :: ('MESH:D008545', 'Disease') :: ['Malignant melanoma of soft parts', 'malignant melanomas', 'cutaneous malignant melanoma', 'malignant melanoma']
@entity320 :: (MESH:D008545,Disease) :: ['malignant melanoma of soft parts']
