BACKGROUND CONTEXT: @entity751 , or progressive noninfectious anterior vertebral fusion, is a rare disorder of unknown etiology that usually presents with @entity1513 in childhood. There have been no long-term reports on outcome in @entity1 with multiple affected levels with longitudinal imaging from infancy to adulthood. PURPOSE: The purpose of this study was to report the long-term outcome of nonoperative management of a @entity1 with @entity751 affecting 19 vertebral levels. STUDY DESIGN: This study is a case report. METHODS: The study included longitudinal clinical and radiological follow-ups. RESULTS: A 1-year-old female presented with @entity1513 . Plain radiographs and magnetic resonance imaging demonstrated @entity1513 associated with anterior disc space narrowing plus T11-T12 and L2-L3 @entity3851 . Initial treatment with a plaster jacket followed by brace failed to prevent progressive @entity3574 and @entity1513 during childhood. At skeletal maturity, no further levels became involved, and progression was halted. In total, 19 levels showed anterior fusion. CONCLUSIONS: This case describes the long-term outcome of nonoperative management for progressive noninfectious anterior vertebral fusion affecting multiple levels. Extensive @entity3574 does not always require surgical intervention. There is a need for future research on the prognostic indicators for progression and long-term outcome.

Long-term clinical and radiological outcomes of XXXX with 19 affected levels: a case report.

@entity1 :: ('9606', 'Species') :: ['children', 'child'] @entity1513 :: ('MESH:D007738', 'Disease') :: ['thoracolumbar kyphosis', 'kyphosis'] @entity3574 :: ('OMIM:277300', 'Disease') :: ['vertebral involvement'] @entity751 :: ('MESH:D013577', 'Disease') :: ['Copenhagen syndrome'] @entity3851 :: ('MESH:D058625', 'Disease') :: ['vertebral end-plate abnormalities']
@entity751 :: (MESH:D013577,Disease) :: ['Copenhagen syndrome']
