PURPOSE: @entity3860 tartrate suppositories are used for treatment of @entity2704 attacks. @entity102 may lead to severe @entity532 such as ulceration, stricture, and @entity3622 . These complications are rare, and only sporadic reports may be found. Nevertheless, awareness of this entity on the part of prescribing physicians and treating colorectal surgeons is essential for a successful outcome, because withdrawal of this medication is an inherent part of treatment. @entity1 : Five female @entity1 were referred for treatment of symptomatic strictures of the anal canal and lower rectum. All of these @entity1 admitted prolonged, nearly daily use of three to seven @entity3860 tartrate suppositories. RESULTS: Three @entity1 with severe @entity850 of the anal verge and anal canal were treated by Y-V anoplasty, and two @entity1 with circular stricture of the lower third of the rectum had balloon dilatations. In all @entity1 the use of @entity3860 suppositories was stopped, and alternative medication was instituted. Long-term follow-up (3-12 years) showed complete resolution of symptoms. CONCLUSION: In view of the availability of new effective drugs for treatment of @entity2704 ( @entity750 agonists) and considering the potentially severe complications of chronic use of @entity3860 , the use of this medication should be abandoned.

XXXX -induced anorectal strictures: report of five cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity3860 :: ('MESH:D004878', 'Chemical') :: ['ergotamine', 'Ergotamine'] @entity532 :: ('MESH:D003925', 'Disease') :: ['anorectal complications'] @entity102 :: ('MESH:D002908', 'Disease') :: ['Chronic abuse'] @entity3622 :: ('MESH:D012006', 'Disease') :: ['rectovaginal fistula'] @entity2704 :: ('MESH:D008881', 'Disease') :: ['migraine headache'] @entity750 :: ('MESH:D012701', 'Chemical') :: ['serotonin'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis']
@entity3860 :: (MESH:D004878,Chemical) :: ['Ergotamine']
