BACKGROUND: @entity18871 in @entity2916 have been managed with various treatment modalities, including @entity544 ( @entity515 ) laser resurfacing. OBJECTIVE: Our purpose was to perform a long-term clinicopathologic assessment of @entity515 laser treatment of @entity18871 . METHODS: This was a retrospective case review of 10 @entity1 treated with a scanning @entity515 laser to flatten lesions. Baseline clinical photographs and those taken at 6, 12, and 24 months after the operation were assessed by a blinded observer. @entity1 also evaluated outcomes. Biopsy specimens taken immediately and at 4 months after the operation were reviewed. RESULTS: Three groups of @entity1 were identified: the first comprised 2 @entity1 with sustained excellent and good outcomes. A second group (3 @entity1 ) had excellent outcomes in the early and medium term but then demonstrated partial deterioration. The last group (5 @entity1 ) had a range of early results with invariably poor outcomes at 24 months. In contrast, @entity1 ' self-assessment at 24 months was good or excellent in 8 of 10 cases. All biopsy specimens taken immediately after the procedure demonstrated ablation extending into the papillary dermis. @entity18871 were present in 6 biopsy specimens. At 4 months, all biopsy specimens showed a band of superficial dermal @entity82 , but distinguishing between this and adjacent @entity18871 was often difficult. Long-term side effects included 2 cases of @entity4182 . CONCLUSION: The long-term results of @entity515 laser treatment of @entity18871 are unpredictable. The marked improvement obtained at 6 months is sustained in only a minority of cases at 24 months. Despite this, @entity1 satisfaction appears relatively high. Initial clinical improvement may be the result of a combination of destruction of @entity18871 and their sequestration under postoperative @entity82 . The benefits of therapy should be weighed against both early morbidity and the risks of long-term complications such as scarring and @entity4182 .

Treatment of @entity18871 with a scanning XXXX laser: a clinicopathologic study with long-term follow-up.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity4182 :: ('MESH:D017496', 'Disease') :: ['subtle hypopigmentation', 'hypopigmentation'] @entity515 :: ('CHEBI:29334', 'Chemical') :: ['CO(2)'] @entity18871 :: ('MESH:D018322', 'Disease') :: ['Residual angiofibromas', 'Facial angiofibromas', 'angiofibromas'] @entity2916 :: ('MESH:D014402', 'Disease') :: ['tuberous sclerosis'] @entity544 :: ('MESH:D002245', 'Chemical') :: ['carbon dioxide']
@entity544 :: (MESH:D002245,Chemical) :: ['carbon dioxide']
