BACKGROUND: Plasma cell @entity1582 is the most common primary @entity79 in adults. However, liver involvement in the form of an initial and asymptomatic nodular plasmacytoma is exceedingly rare. CASE REPORT: A 64-year-old male was found to have a right hepatic lobe nodule on a routine abdominal ultrasound prior to bariatric surgery. Liver biopsy revealed a @entity8450 that, given the location of the lesion, was favored to represent a @entity706 with prominent plasmacytic differentiation. Positron emission tomography (PET) demonstrated a hypermetabolic @entity99 and identified @entity75 . Biopsy of a clavicular lesion revealed sheets of plasma cells and confirmed the diagnosis of @entity1582 . The @entity1 underwent 6 cycles of chemotherapy with @entity786 , @entity1749 , and @entity619 before transitioning to @entity6985 and @entity619 because of early disease progression. Although the @entity1 had International Staging System I (low-risk) disease, his disease demonstrated an aggressive clinical course and resistance to multiple lines of therapy. CONCLUSION: Extramedullary nodular hepatic plasmacytoma is exceedingly rare. Nevertheless, extramedullary plasmacytomas should be included in the differential diagnosis of @entity1 with indistinct hepatic lesions visualized on computed tomography scan, especially if PET scans show associated @entity75 . In general, extramedullary plasmacytomas are a poor prognostic sign and a harbinger of an aggressive clinical course in the context of @entity1582 .

Asymptomatic XXXX Presenting as a Nodular Hepatic Lesion: A Case Report and Review of the Literature.

@entity1 :: ('9606', 'Species') :: ['patient', 'patients'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic mass'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma'] @entity75 :: ('MESH:D001927', 'Disease') :: ['multiple destructive bony lesions', 'bony lesions'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide'] @entity1582 :: ('MESH:D009101', 'Disease') :: ['multiple myeloma', 'myeloma'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone malignancy'] @entity619 :: ('MESH:D003907', 'Chemical') :: ['dexamethasone'] @entity6985 :: ('MESH:C467567', 'Chemical') :: ['lenalidomide'] @entity1749 :: ('MESH:C400082', 'Chemical') :: ['bortezomib'] @entity8450 :: ('MESH:D054219', 'Disease') :: ['plasma cell neoplasm']
@entity1582 :: (MESH:D009101,Disease) :: ['Multiple Myeloma']
