We have performed DNA analysis by means of fluorescence-activated cell cytometry on @entity982 -embedded tissue from the diagnostic biopsy specimens in 40 cases of @entity1893 ( @entity1893 ) and 25 of @entity978 ( @entity978 ) and from 50 normal tonsils as controls. For @entity978 cases, @entity2007 was found in 7 of 25 (28%), a higher proportion than in two previous studies of mainly adult @entity1 . @entity5 showed @entity4889 ( @entity4889 ) similar to those of controls. In the @entity1893 cases @entity2007 was found in 12 of 40 (30%) with no significant association with site, stage, histopathology, immunophenotype, or prognosis. @entity4889 were highest in abdominal and chest primary sites but were not related to stage. @entity2109 had the highest @entity4889 relative to lymphoblastic (P < .01) and @entity706 (P < .05). Significantly higher @entity4889 were found in B cell than in T cell @entity5 (P < .001). There was considerable heterogeneity for @entity4889 within each @entity1893 subgroup. Survival was worse at 5 years for those with high @entity4889 compared with those with normal @entity4889 (P = .04). These results suggest that @entity5 DNA analysis may be useful in the evaluation of @entity1 with @entity1893 . Larger studies are needed to define its role as an independent prognostic variable.

Analysis of ploidy and proliferative activity in XXXX ( @entity1893 ) and @entity978 ( @entity978 ).

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity2007 :: ('MESH:D000782', 'Disease') :: ['aneuploidy'] @entity4889 :: ('MESH:D018455', 'Disease') :: ['SPFs', 'S-phase fractions'] @entity706 :: ('MESH:D008223', 'Disease') :: ['centroblastic lymphomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Diploid tumors', 'tumors'] @entity2109 :: ('MESH:D002051', 'Disease') :: ["Burkitt's lymphomas"] @entity982 :: ('MESH:D010232', 'Chemical') :: ['paraffin'] @entity1893 :: ('MESH:D008228', 'Disease') :: ["non-Hodgkin's lymphoma", 'NHL'] @entity978 :: ('MESH:D006689', 'Disease') :: ['HD', "Hodgkin's disease"]
@entity1893 :: (MESH:D008228,Disease) :: ['childhood non-Hodgkin's lymphoma']
