BACKGROUND: There is no study of circumferential EMR in @entity1 with @entity355 containing early stage malignant lesions. This study investigated the effectiveness and safety of circumferential EMR by using a simple snare technique without cap. METHOD: @entity1 with @entity355 containing multifocal high-grade intraepithelial @entity5 or @entity5 , and @entity1 with endoscopically nonidentifiable early stage malignant mucosal changes incidentally detected in random biopsy specimens were included in the study. A 30 x 50-mm polypectomy snare made of monofilament 0.4-mm steel wire was used without any additional device or submucosal injection. RESULTS: Twelve @entity1 (10 @entity1 , 2 @entity1 ; median age 63.5 years, range 43-88 years) underwent circumferential EMR; 5 had multifocal lesions, and 7 had no visible lesions. Segments of Barrett's epithelium were circumferential (median length 5 cm) and completely removed. The median number of EMR sessions was 2.5. The median number of snare resections per EMR session was 5. The medial total area of mucosa in resected specimens per session was 3.8 cm(2). Two @entity1 developed strictures that were successfully treated by bougienage. Minor @entity548 occurred during 4 of 31 EMR sessions. During a median follow-up of 9 months, no recurrence of @entity355 or @entity5 was observed. CONCLUSIONS: Circumferential EMR with a simple snare technique is feasible, safe, and effective for complete removal of Barrett's epithelium with early stage malignant changes.

Circumferential EMR and complete removal of Barrett's epithelium: a new approach to management of @entity355 containing high-grade intraepithelial XXXX and intramucosal carcinoma.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity5 :: ('MESH:D009369', 'Disease') :: ['intramucosal cancer', 'malignancy', 'neoplasia'] @entity355 :: ('MESH:D001471', 'Disease') :: ["Barrett's esophagus"] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding']
@entity5 :: (MESH:D009369,Disease) :: ['neoplasia']
