PURPOSE: @entity22321 is a benign lesion with unpredictable behavior. Its treatment is challenging, especially in poorly accessible surgical areas, such as spine and pelvis. Currently, the first-line treatment of @entity22321 is repeated @entity1416 ( @entity1416 ) until healing. Other options have been used with variable success rates. We propose an alternative treatment for spine @entity80 (sABC) based on the injection of concentrated autologous bone marrow. METHODS: We retrospectively report and analyze here two cases of @entity1 , a 14-year-old @entity1 and a 16-year-old @entity1 , both affected by @entity22321 in C2 vertebra which were impossible to treat by @entity1416 . They were treated with single or repeated injection of concentrated autologous bone marrow into the lesion. Their follow-up period is 27  months for both @entity1 . RESULTS: In the two cases reported here we observed a progressive ossification of the lesion, which was slow in one case, requiring three subsequent injections of concentrated bone marrow, and fast in the other case, beginning 1  month after the procedure. In both cases, the healing of the lesion was associated with symptom relief and the clinical status of the @entity1 remains stable after 2  years. CONCLUSIONS: Although @entity1416 can still be considered the first line in the treatment of @entity22321 in the axial skeleton, new promising therapeutic procedures involving the use of mesenchymal stem cells are developing.

XXXX of the spine treated by concentrated bone marrow: clinical cases and review of the literature.

@entity22321 :: ('10058', 'Gene') :: ['ABC'] @entity1 :: ('9606', 'Species') :: ['girl', 'patients', 'boy'] @entity80 :: ('MESH:D017824', 'Disease') :: ['aneurysmal bone cyst'] @entity1416 :: ('MESH:D020762', 'Disease') :: ['SAE', 'selective arterial embolization']
@entity80 :: (MESH:D017824,Disease) :: ['Aneurysmal bone cyst']
