PURPOSE: To identify characteristic features of @entity2124 ( @entity2124 )-producing @entity977 . MATERIALS AND METHODS: A total of 174 pathologically proven @entity977 were evaluated retrospectively on magnetic resonance (MR) images to determine the signal intensity (on T2-weighted images), maximum diameter, and amount of suprasellar and infrasellar extension. For microadenomas, sellar depth was also measured. @entity2124 -producing @entity652 were classified at histologic evaluation as densely or sparsely granulated. Specimens from 38 @entity652 were stained to assess the amounts of fibrous tissue, @entity68 , and amyloid they contained. Results were correlated with the size and hormonal activity of @entity652 by using the chi2, unpaired t, and Mann-Whitney U tests. RESULTS: Among 174 @entity977 , 42 were @entity2124 -producing @entity652 . Of these, 16 were densely granulated, and 24 were sparsely granulated (two histologic specimens were lost). Signal intensity was evaluated among 153 @entity652 . On T2-weighted MR images, hypointensity was seen more commonly in @entity652 that produced @entity2124 (16 of 40 cases [40%]; P <.001) than in those that did not; hypointensity was nearly exclusive to densely granulated @entity2124 -producing @entity652 . The amounts of amyloid, fibrous tissue, and @entity68 contained in @entity652 demonstrated little relationship with signal intensity. Average suprasellar extension was significantly smaller in @entity652 that produced @entity2124 (-0.8 mm) than in those that did not (5.3 mm) (P <.001). @entity2124 -producing @entity652 tended to demonstrate infrasellar extension rather than suprasellar extension. Average sellar depth associated with @entity2124 -producing microadenomas (13.3 mm) was significantly greater than for non- @entity2124 -producing microadenomas (9.7 mm; P <.001). CONCLUSION: Characteristic features regarding growth direction and T2 signal intensity can be identified for @entity2124 -producing @entity652 .

Comparison of XXXX -producing and non- @entity2124 -producing @entity977 : imaging characteristics and pathologic correlation.

@entity2124 :: ('2688', 'Gene') :: ['GH', 'growth hormone'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenomas'] @entity977 :: ('MESH:D010911', 'Disease') :: ['pituitary adenomas'] @entity68 :: ('MESH:D007501', 'Chemical') :: ['iron']
@entity2124 :: (2688,Gene) :: ['growth hormone']
