OBJECTIVE: Recent studies suggest an increased prevalence of obstetric complications in female carriers of hereditary or acquired @entity49 . The aim of the study was to determine if carriership of the factor V (FV) Leiden mutation (activated protein C [APC] resistance) is higher in @entity1 who have had of @entity5869 during pregnancy. DESIGN: A retrospective case-control study. SETTING: University Hospital MAS, Malm  , Sweden. METHODS: A comparison of 102 @entity1 with @entity5869 with 2371 prospectively collected controls. Carriership of FV Leiden was determined and the @entity1 were interviewed. MAIN OUTCOME MEASURES: Proportion of FV Leiden carriership, first degree heritage of @entity715 and previous @entity5869 in cases and controls. RESULTS: Carriage of FV Leiden was found in 15.7% of @entity1 who have had @entity5869 as compared with 10.8% of controls (P = 0.12, odds ratio [OR] = 1.5, 95% confidence interval [CI] = 0.9-2.7). Around 20% of @entity1 with @entity5869 reported first degree heritage for @entity49 , as compared with 6.7% of controls (P < or = 0.001). CONCLUSIONS: FV Leiden carriership was not significantly different in @entity1 with @entity5869 . However, there was an increased prevalence of first degree heritage for @entity49 in @entity1 with @entity5869 , indicating a higher prevalence of @entity49 among @entity1 with @entity5869 .

Factor V Leiden in pregnancies complicated by XXXX .

@entity1 :: ('9606', 'Species') :: ['women'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity49 :: ('MESH:D019851', 'Disease') :: ['venous thrombosis', 'thrombophilias', 'thrombophilia'] @entity5869 :: ('MESH:D000037', 'Disease') :: ['placental abruption']
@entity5869 :: (MESH:D000037,Disease) :: ['placental abruption']
