The aim of this study was to investigate the influence of @entity281 as indicated by leukocytospermia on @entity1 sperm morphology, diagnosed cytologically and by means of a leukocyte peroxidase test. A basic semen analysis, including a leukocyte peroxidase test, was prospectively performed on 150 consecutive semen samples. Cytology smears were microscopically investigated for the presence of WBC and the results expressed on a 4 point scale as +/- to +3 @entity2194 ( @entity2194 ). ROC curve analysis indicated that for cases with more than +/- WBC/ @entity2194 the peroxidase determined WBC count cut-off value was > 0.25 x 10(6) WBC ml-1 with a sensitivity of 75% and specificity of 90%. The presence of more than +/- WBC/ @entity2194 was negatively correlated with sperm morphology characteristics studied. The mean (+/- SD) percentage of morphological normal spermatozoa was 7.0% (SD 4.4) in the WBC negative group (n = 134) compared to 4.3% (SD 3.5) in the WBC positive (n = 16) group (P < 0.0001). There was also an associated increase, 15.3% (SD 13.3) to 23.6% (SD 13.8), in the percentage of spermatozoa with elongated head forms in the WBC positive group (P = 0.0218). No other effect on sperm and acrosome morphology could be found. With the peroxidase determinations there was also a tendency in the WBC positive group (n = 10) towards poorer sperm morphology characteristics, but these changes were not statistically significant. The presence of @entity281 as diagnosed cytologically was associated with statistically poorer sperm morphology characteristics. This statistical relationship was not found in the peroxidase diagnosed leukocytospermia positive groups.

Sperm morphology and male XXXX .

@entity1 :: ('9606', 'Species') :: ['human'] @entity281 :: ('MESH:D007239', 'Disease') :: ['urogenital infections'] @entity2194 :: ('MESH:D005128', 'Disease') :: ['HPF', 'WBCs/high power field']
@entity281 :: (MESH:D007239,Disease) :: ['urogenital infections']
