Despite its simplicity, device closure of @entity118 is still associated with rare but potentially lethal complications. In this prospective non-randomized multicenter study we investigated the safety and efficacy of the Cocoon septal occluder (CSO) for closure of @entity118 ( @entity118 ) in 92 @entity1 . Median age of the @entity1 was 10.5years (range 3-61years) and median weight was 25kg (range 13-65kg). The device is an improved new generation double disc design made of @entity5648 wire mesh that is coated with @entity902 using NanoFusion technology. The discs are connected by a waist with diameter ranging from 6mm to 40mm with 2mm increments. All @entity1 completed a 3-month follow-up. Mean ASD diameter was 21  7mm (range 10-35mm), while the mean device diameter was 24  8mm (range 14-40mm). The CSO was permanently implanted in all 92 @entity1 . Complete echocardiographic closure of the defect immediately after the procedure or at the one month follow-up, was observed in all 92 @entity1 (100%). No device-related complications were observed during the procedure or at short-term follow-up (range 3-12months). Our preliminary results indicate that CSO is a promising device for transcatheter closure of @entity118 . Further studies are required to document its efficacy, safety and long-term results in a larger @entity1 population.

Catheter closure of XXXX using the Cocoon septal occluder: Preliminary results of a European multicenter study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity118 :: ('MESH:D006344', 'Disease') :: ['atrial septal defects', 'ASDs'] @entity902 :: ('MESH:D010984', 'Chemical') :: ['platinum'] @entity5648 :: ('MESH:C013616', 'Chemical') :: ['Nitinol']
@entity118 :: (MESH:D006344,Disease) :: ['atrial septal defects']
