Aversive conditioning has an impact on the neural signal for the gustatory conditioned stimulus (CS). Here, we determined whether the code is also affected by preference conditioning. We paired the taste of @entity8723 (CS+) with intragastric nutrients in some @entity35 (MG), and @entity1792 (CS+) with nutrients in others (CI). A control group (Control) experienced both tastants without nutrients. Preferences (>90%) developed for each CS+. We recorded responses to 16 taste stimuli in the nucleus of the solitary tract. Responsiveness of acid-oriented neurons to @entity8723 in MG @entity35 was lower than in Controls, and its profile was more distinct from those of acidic and bitter stimuli. Total activity to @entity1792 was unchanged in CI @entity35 . However, its temporal profile showed a decreased phasic component, making @entity1792 temporally distinct from nonsugars. Therefore, the responses to both CS+ were modified, each in its own manner, to be more distinct from those of aversive stimuli. The effects of preference conditioning, however, were weaker than those of aversive conditioning.

Preference conditioning alters taste responses in the nucleus of the solitary tract of the XXXX .

@entity35 :: ('10116', 'Species') :: ['rats'] @entity1792 :: ('MESH:D019343', 'Chemical') :: ['citric acid'] @entity8723 :: ('MESH:D015636', 'Chemical') :: ['MgCl2']
@entity35 :: (10116,Species) :: ['rat']
