Young, specific-pathogen-free @entity468 were fed purified diets containing different sources of fat. Food intake was depressed and @entity468 lost weight when the diet contained either hydrogenated coconut oil ( @entity264 ) or medium-chain @entity1674 (MCT). With an MCT preparation enriched in 8:0 (MCT8), @entity468 would not eat after first tasting the diet. When @entity468 were offered a choice of two high-fat diets, they chose the basal diet over a diet containing 30% @entity264 , by a ratio of 4.5:1. Low levels of MCT8 (5% or 10% by weight) were also rejected, whereas @entity468 did not reject 5% or 15% MCT12. @entity6212 , at 0.1-1.0% of the diet, was rejected. In other studies, food intake and body weight decreased when @entity264 was added to a fat-free diet. @entity468 fed 25% or 35% @entity264 lost weight. When 5% safflower seed oil was added to the @entity264 diets, body weights and food intake improved, but were still less than optimal. These studies indicate that the food intake @entity308 in @entity468 fed dietary @entity264 and MCT is primarily a result of impalatability, and that the @entity844 moiety may be responsible for the aversion.

Aversion of the cat to dietary medium-chain XXXX and @entity6212 .

@entity6212 :: ('MESH:C031492', 'Chemical') :: ['Caprylic acid'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity844 :: ('CHEBI:35366', 'Chemical') :: ['fatty acid'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity468 :: ('9685', 'Species') :: ['Cats', 'cats'] @entity264 :: ('CHEBI:17478', 'Chemical') :: ['HCO']
@entity1674 :: (MESH:D014280,Chemical) :: ['triglycerides']
