OBJECTIVE: To evaluate the clinical performance of the Cre8    polymer-free drug-eluting-stent in unselected real-life population. BACKGROUND: @entity32 plays a key role in the multi-factorial process eventually leading to @entity177 ( @entity177 ) after drug-eluting-stent (DES) implantation. The local chronic inflammatory reaction in the vessel wall at the site of stent implantation is, at least in part, attributed to interaction between the polymer coating of @entity4743 and vessel wall components. The belief that elimination of the polymer will reduce the occurrence of short and long-term @entity177 has led to the field of polymer-free DES development. METHODS AND RESULTS: In this prospective, open-labeled, single-center, uncontrolled trial we enrolled consecutive @entity1 undergoing PCI to receive the Cre8    stent. The only exclusion criteria were in-stent restenosis and target vessel diameter <2.5mm. Primary end points were @entity204 and @entity177 ( @entity177 ) at 1-year. Overall, 215 @entity1 were enrolled, in which 318 Cre8 stents were implanted. Study population was characterized by a high prevalence of comorbidities including 38% of @entity6 . More than 50% presented with @entity1187 . During 1-year of follow-up there were 1 case of @entity944 and 1 case of @entity204 , as well as 2 cases of @entity177 . CONCLUSION: In this small single-center trial of unselected real-life population, the polymer-free Cre8    DES appears to be effective, as it was associated with very low rates of target-vessel-failure up to 1-year follow-up.

Polymer-free drug-eluting stent in unselected XXXX population: a single center experience.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['Inflammation'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndromes'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetics'] @entity944 :: ('MESH:D003645', 'Disease') :: ['sudden death'] @entity4743 :: ('CHEBI:37628', 'Chemical') :: ['DES'] @entity177 :: ('MESH:D051437', 'Disease') :: ['target vessel failure', 'TVF'] @entity204 :: ('MESH:D003643', 'Disease') :: ['non-cardiac death', 'cardiac death']
@entity1 :: (9606,Species) :: ['patient']
