BACKGROUND: A solid knowledge associated with @entity2649 ( @entity2649 )-related @entity281 in spontaneous @entity510 ( @entity510 ) @entity1 is necessary and that would be useful in taking effective measures to cope with this complication. We aimed to describe incidence rates and risk factors associated with @entity2649 -related @entity281 in @entity510 @entity1 . METHODS: A retrospective review was performed on @entity510 @entity1 who underwent @entity2649 between July 2010 and August 2015. @entity1 charts were reviewed to retrieve demographic, clinical, and laboratory data. @entity2649 -related @entity281 were defined based on culture results of cerebrospinal fluid in combination with clinical symptoms. Infection rates were calculated, and a logistic regression model was developed to identify risk factors. RESULTS: A total of 629 @entity510 @entity1 (25-82  years age range, 42.8  % male) were treated with @entity2649 in the period. @entity2649 -related @entity281 were identified in 36 @entity1 (5.7  %). Longer duration of @entity2649 (>= 4  days: p  =  0.0037) and puncture site leakage (p  <  0.0001) appeared to be risk factors for @entity281 . The @entity281 rate increased with length of the hospital stay (16-20  days: p  =  0.0032; >= 21  days: p  =  0.0007). 84.6  % of the isolated bacteria were Gram-positive, and the most commonly associated pathogens were @entity3256 -resistant coagulase-negative Staphylococcus (MRCNS, 61.5  %). CONCLUSIONS: The @entity1 with @entity2649 for more than 4  days or with puncture site leakage had more risk of @entity281 . Infected @entity1 were more likely to stay longer in the hospital. MRCNS were identified as the most frequent causal pathogens. And the use of antibiotics during @entity2649 did not appear to reduce the risk of @entity281 .

Risk Factors for Infections Related to Lumbar Drainage in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity3256 :: ('MESH:D008712', 'Chemical') :: ['Methicillin'] @entity510 :: ('MESH:D013345', 'Disease') :: ['SAH', 'subarachnoid hemorrhage'] @entity2649 :: ('MESH:C563613', 'Disease') :: ['LD', 'lumbar drainage'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'infections']
@entity510 :: (MESH:D013345,Disease) :: ['Spontaneous Subarachnoid Hemorrhage']
