The aim of the present study was to determine the prevalence of @entity2523 fimA genotypes in Caucasian @entity1 with @entity2521 . A total of 102 @entity1 harboring @entity2523 subgingivally were enrolled into the study. Pooled @entity527 samples of the six most severely affected sites were taken and analysed by fimA-specific polymerase chain reaction (PCR) and restriction analysis. Moreover, 26 @entity2523 isolates were analysed by sequence analysis of the fimA gene. Sequence analysis revealed five major fimA genotypes (fimA types I-V) and allowed further subtyping of fimA genotypes II and IV into two subgroups each. The overall prevalences of fimA genotypes as assessed by PCR and restriction analysis among the @entity2523 -positive @entity1 with @entity2521 were: type I, 25.5%; type II, 38.2%; type III, 4.9%; type IV, 18.6%; type V, 3.9%; and non-typable, 6.9%. Two @entity1 were colonized by both @entity196 , or type III and type IV fimA genotypes, respectively. @entity1 harboring different fimA genotypes showed no significant difference in severity of @entity2520 , as assessed by pocket probing depth and @entity548 on probing following adjustment for smoking habit and age. The results indicate that predominant fimA genotypes in Caucasian @entity2521 @entity1 are types I, II, and IV. However, there was no difference in the association of the various fimA genotypes with disease severity.

Prevalence of XXXX fimA genotypes in Caucasians.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity527 :: ('MESH:D058225', 'Disease') :: ['subgingival plaque'] @entity2520 :: ('MESH:D010510', 'Disease') :: ['periodontal disease'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity196 :: ('MESH:D020754', 'Disease') :: ['type II and type IV'] @entity2521 :: ('MESH:D010518', 'Disease') :: ['periodontitis'] @entity2523 :: ('837', 'Species') :: ['Porphyromonas gingivalis', 'P. gingivalis']
@entity2523 :: (837,Species) :: ['Porphyromonas gingivalis']
