BACKGROUND: Primary percutaneous intervention (PPCI) is the treatment of choice for @entity583 ( @entity583 ) but robust evidence in the very elderly is lacking. We compared PPCI outcomes between different age quartiles (quartile 1 < 60 years, quartile 2 >=  60 to < 70 years, quartile 3 >=  70 to < 80 years, quartile 4 >=  80 years). METHODS: Retrospective observational analysis of our Morriston Tertiary Cardiac Center (Abertawe Bro Morgannwg University Health Board) @entity1 from 2005 to 2010 with @entity583 who underwent PPCI. RESULTS: Of 434 @entity1 , 57 (13%) were in quartile 4 (>=  80 years). In older age quartiles, @entity1 were less likely to receive a drug eluting stent (DES, P = 0.001) or glycoprotein IIb/IIIa inhibitor (GPI, P < 0.0001). Increase in age was associated with reduced time to survival (b-coefficient: -0.192, t: -3.70, 95%CI: -4.91 to -1.50, P < 0.0001) as was the presence of @entity1455 (b-coefficient: -0.194, t = 3.77, 95%CI: -5.26 to -1.65, P < 0.0001). Use of GPI was associated with increased time to survival (b-coefficient: 0.138, t = 2.82, 95%CI: 1.58-8.58, P = 0.005) but older age quartiles were less likely to receive GPI (P < 0.0001). In-hospital mortality (1.8% quartile 1, 3.6% quartile 2, 10.9% quartile 3 and 12.3% quartile 4, P = 0.002) and 1-year mortality (5.4% quartile 1, 5.5% quartile 2, 16.8% quartile 3 and 24.6% quartile 4, P < 0.0001, respectively) was significantly higher in older age quartiles. CONCLUSIONS: Increased short term and intermediate term mortality is seen in the very elderly after PPCI. Age and @entity1455 were prognostic factors. Intervention should not be based on age alone and awareness regarding prognostic factors can help improve management.

Age and outcomes of primary percutaneous intervention for XXXX in a tertiary center-are we there yet?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST elevation myocardial infarction'] @entity1455 :: ('MESH:D012770', 'Disease') :: ['cardiogenic shock']
@entity583 :: (MESH:D009203,Disease) :: ['ST elevation myocardial infarction']
