The management of PABC is very difficult. The incidence of PABC is low, but may be increasing because of the number of @entity1 who are becoming pregnant at a later age. More investigation is needed to understand whether the biology of PABC is different from that of @entity0 in nonpregnant @entity1 . One exciting area of further research is the potential relationship between mutations in known @entity0 susceptibility genes and @entity0 development during pregnancy. Diagnosis or PABC remains challenging because of the anatomic and physiologic changes that occur in the breast during pregnancy. Understanding the generic influences on PABC may help physicians in diagnosing this disease earlier, and understanding the tumor-receptor characteristics of PABC can help physicians deliver effective treatment. The various modalities available for treatment of PABC and their risks and benefits must be discussed openly with @entity1 and their families. Abortion is not usually recommended. Modified radical mastectomy is the recommended treatment for PABC diagnosed during the first trimester. Neoadjuvant or adjuvant chemotherapy can be given with minimal risks to the fetus during the second or third trimester. Radiation therapy is contraindicated during pregnancy because of the potential for @entity130 . Breast conservation therapy, with radiation treatments given after delivery or after neoadjuvant chemotherapy, is an option for @entity1 with PABC diagnosed late in pregnancy. Once the appropriate treatment modality is chosen, its implementation must not be delayed because of the pregnancy. Most of the literature shows that @entity1 with PABC have the same survival stage for stage as nonpregnant @entity1 with @entity0 . But some studies suggest that the prognosis is worse for @entity1 who present with advanced-stage PABC. Finally, recurrence and survival in most @entity1 previously treated for @entity0 do not appear to be adversely affected by subsequent pregnancy. Above all, the @entity1 with @entity0 diagnosed during pregnancy is best served by early and continued involvement of a multidisciplinary @entity5 treatment team.

Multidisciplinary management of XXXX concurrent with pregnancy.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity130 :: ('MESH:D014947', 'Disease') :: ['injury to the fetus']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
