BACKGROUND: Increases in the detection of early @entity356 have indisputably, improved long-term survival. The aim of this study was to establish the value of periodic gastric endoscopy and the appropriate intervals for its performance. METHODS: We compared, retrospectively, the clinicopathologic characteristics and outcomes of two groups of @entity1 who had undergone surgical treatment for @entity356 . Of a total of 361 @entity1 , 106 had undergone endoscopic examination within 2 years before the detection of @entity356 (group 1), and 255 had either undergone no endoscopic examination or had had endoscopic examination more than 2 years before the detection of @entity356 (group 2). For the evaluation of survival rate, the @entity1 in each group were classified into two subgroups: group 1a, endoscopic examination within 1 year before detection; group 1b, endoscopic examination more than 1 year and within 2 years; group 2a, endoscopic examination more than 2 years and within 4 years before detection; and group 2b, endoscopic examination more than 4 years before detection, or no endoscopic examination. RESULTS: @entity356 in group 1 was characterized by small @entity5 size, no @entity5 invasion beyond the submucosa, few instances of lymphatic and vascular permeation, and few lymph node @entity3 . The 5-year survival rate for group 1 @entity1 (96.5%) was significantly higher than that for group 2 @entity1 (71.0%; P < 0.01). The survival rates for group 1a @entity1 and group 1b @entity1 were not significantly different (P = 0.4595). The survival rate for @entity1 in group 2a was significantly lower than that for those in group 1a (P < 0.05). CONCLUSION: Periodic gastric endoscopy enables early detection of @entity5 , thereby improving survival. The optimal interval for periodic examination appears to be 2 years.

Effect of periodic endoscopy for XXXX on early detection and improvement of survival.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'Gastric cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
