UNASSIGNED: Objective: To examine the association between serum lipids, including total @entity165 (TC), @entity412 (TG), high-density lipoprotein @entity165 (HDL-C) and low-density lipoprotein @entity165 (LDL-C), and the risk and progression of @entity0 in postmenopausal and premenopausal @entity1 . Methods: A review analysis of female @entity1 who underwent @entity0 surgery and blood lipid metabolism testing in Tianjin One Hospital, from January 2013 to October 2013, was performed. A total of 1 081 @entity1 were included in the final analysis. The control group consisted of 2 981 @entity1 without @entity0 . We collected all of the cases' demographic, pathology, lymph nodes metastasis information, was used to testify the difference of serum lipid level between @entity1 and control group, also the postmenopausal and pre-menopausal groups. Results: The average age of the @entity1 and control subjects were (51.6  0.3) and (51.0  0.2) years, respectively. Serum TC and LDL-C levels in the @entity1 group, (5.16   0.03) and (3.28  0.26) mmol/L, respectively, were significantly higher than in the control group, (5.02  0.01) and (2.51    0.01) mmol/L, respectively (t values 3.89 and 4.81 and P<0.001). HDL-C levels in the @entity1 group, (1.60  0.01) mmol/L, were significantly lower than in the control group, (1.65  0.01) mmol/L (t=3.90, P<0.001). Similar observations were made in postmenopausal patients. Serum TC and LDL-C levels in the postmenopausal @entity1 group, (5.48  0.04) and (3.27  0.03) mmol/L, respectively, were significantly higher than in control subjects, (5.24  0.02) and (2.71  0.02) mmol/L, respectively (t values 4.75 and 15.30, all P values <0.001). HDL-C levels in postmenopausal @entity1 , (1.60  0.02) mmol/L, were significantly lower than in the control group, (1.69  0.01) mmol/L (t=4.85 , P<0.001). In the @entity0 @entity1 group, those at pathological stages 0-    had lower TG levels than those at    -   . These values were (1.19  0.05) and (1.43   0.09) mmol/L, respectively (t=2.69, P<0.001). Meanwhile, @entity1 with no lymph node @entity3 had lower TG levels than the lymph node-positive group, with values of (1.15    0.05) and (1.37    0.07) mmol/L, respectively (t=2.53, P=0.012). Conclusion: We found that @entity2299 may affect the incidence of @entity0 , particularly among postmenopausal women. Serum lipids may promote @entity5 progression through higher TG and low HDL-C levels.

[A case-control study on the association between serum lipid level and the risk of XXXX ].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity2299 :: ('MESH:D050171', 'Disease') :: ['dyslipidemia'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
