BACKGROUND: Intradialytic @entity101 is a condition where there is an increase in blood pressure (BP) from pre- to post-hemodialysis; this condition has been recently identified as an independent mortality risk factor in hypertensive hemodialysis @entity1 . The mechanisms and management of intradialytic @entity101 have been explored in numerous research studies over the past few years. SUMMARY: @entity1 with intradialytic @entity101 have been found to be more chronically volume overloaded compared to other hemodialysis @entity1 , although no causal role has been established. @entity1 with intradialytic @entity101 have intradialytic vascular resistance surges that likely explain the BP increase during dialysis. Acute intradialytic changes in endothelial cell function have been proposed as etiologies for the increase in vascular resistance, although it is unclear if @entity2232 or some other vasoconstrictive peptide is responsible. There is an association between dialysate to serum @entity1372 gradients and BP increase during dialysis in @entity1 with intradialytic @entity101 , although it is unclear if this is related to endothelial cell activity or acute osmolar changes. In addition to probing the dry weight of @entity1 with intradialytic @entity101 , other management strategies include lowering dialysate @entity1372 and changing antihypertensives to include @entity1405 or other poorly dialyzed antihypertensives. KEY MESSAGES: Hemodialysis @entity1 with intradialytic @entity101 have an increased mortality risk compared to @entity1 with modest decreases in BP during dialysis. Intradialytic @entity101 is associated with extracellular @entity1284 in addition to acute increases in vascular resistance during dialysis. Management strategies should include reevaluation of dry weight and modification of both the dialysate prescription and medication prescription.

Mechanisms and Treatment of Intradialytic XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity2232 :: ('1906', 'Gene') :: ['endothelin-1'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity1405 :: ('MESH:C043211', 'Chemical') :: ['carvedilol'] @entity1284 :: ('MESH:D019190', 'Disease') :: ['volume overload']
@entity101 :: (MESH:D006973,Disease) :: ['Hypertension']
