BACKGROUND: Drug-induced or "pill-induced" @entity2910 may be secondary to the prolonged contact of the drug with the esophageal mucosa or secondary to the drug ability to alter the local conditions. The @entity561 , a bone resorption inhibitor used in the treatment and prevention of @entity170 , has been cited, recently, as one of the causes of adverse upper @entity344 . AIM: To describe the clinical, endoscopic and histopathological features of @entity1 with @entity1066 associated with @entity561 . @entity1 : Four @entity1 and one @entity1 with @entity170 were treated with @entity561 and submitted to endoscopy followed esophageal biopsy. RESULTS: The age range of the @entity1 was from 64 to 84 years old. The @entity1 showed @entity1109 after taking @entity561 during a period of 2-12 months. At endoscopic evaluation, the mucosa was friable, with @entity2681 and/or @entity1066 covered by fibrin in the distal esophagus. The pathological examination of the esophageal biopsies revealed @entity1066 characterized by necrofibrinpurulent material, granulation tissue, and yellow refractile polarizable crystal. The @entity1 ' symptoms resolved after stopping @entity561 use. CONCLUSIONS: The esophagus injuries associated with @entity561 are not frequent and seem to be associated with the incorrect use of medication. The endoscopists and pathologists should be alert to the possibility of @entity561 therapy in cases of diagnosis of @entity1066 in ancient @entity1 , particularly in @entity1 . The recognition of this condition would improve the @entity1 care.

[ @entity1066 associated with the use of XXXX : histopathological and endoscopic features].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'PATIENTS', 'man'] @entity2681 :: ('MESH:D014077', 'Disease') :: ['erosion'] @entity2910 :: ('MESH:D004941', 'Disease') :: ['esophagitis'] @entity561 :: ('MESH:D019386', 'Chemical') :: ['alendronate sodium'] @entity170 :: ('MESH:D010024', 'Disease') :: ['osteoporosis'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcerative esophagitis', 'ulceration'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal tract injury'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['dyspeptic symptoms']
@entity561 :: (MESH:D019386,Chemical) :: ['alendronate sodium']
