BACKGROUND: the aim of this study was to investigate the effects of spinal anesthesia using two different doses of @entity3575 combined with low-dose @entity1343 in anorectal surgery. METHODS: in this prospective, double-blind study, 52 American Society of Anaesthesiologists I-II @entity1 scheduled for elective anorectal surgery were randomized into two groups. The @entity1 in group I received intrathecal 2.5mg hyperbaric @entity1343 plus 12.5 g @entity3575 and in group II received intrathecal 2.5mg hyperbaric @entity1343 plus 25 g @entity3575 . All the @entity1 remained in the seated position for 5min after completion of the spinal anesthesia. Sensory block was evaluated with pin-prick test and motor block was evaluated with a modified Bromage scale. RESULTS: motor block was not observed in both of the groups. The sensory block was limited to the S2 level in group I, and S1 level in group II. None of the @entity1 required additional analgesics during the operation. Time to two-segment regression was shorter in group I compared with group II (p<0.01). One @entity1 in group I and 5 @entity1 in group II had @entity111 . Hemodynamic parameters were stable during the operation in both of the groups. CONCLUSION: spinal saddle block using hyperbaric @entity1343 with both 12.5 g and 25 g @entity3575 provided good quality of anesthesia without motor block for anorectal surgery in the prone position.

Low-dose @entity1343 plus XXXX combination for spinal anesthesia in anorectal surgery.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1343 :: ('MESH:C476513', 'Chemical') :: ['levobupivacaine'] @entity3575 :: ('MESH:D005283', 'Chemical') :: ['fentanyl'] @entity111 :: ('MESH:D011537', 'Disease') :: ['pruritus']
@entity3575 :: (MESH:D005283,Chemical) :: ['fentanyl']
