PURPOSE: The purpose of this study was to clarify the characteristics of adult cases with instability due to upper cervical spine anomalies who needed fusion surgery regarding the clinical and radiological findings. METHODS: Twenty-two consecutive @entity1 with instability due to @entity64983 in adult cases were reviewed. The @entity154 included @entity9807 in nine cases, os odontoideum in seven cases, occipitalization of the atlas in four cases, @entity7194 in one case and @entity24293 with another @entity154 in one case. We evaluated the severity of @entity16 before surgery and at the last follow-up. We also observed MR images before and 1  year after surgery. RESULTS: Before surgery, the 22 @entity1 included seven Ranawat Grade I cases, ten Ranawat Grade II cases, and five Ranawat Grade IIIa cases. Regarding the neurological status after surgery, those included eighteen Ranawat Grade I cases, three Ranawat Grade II cases, and one Ranawat Grade IIIa case. Preoperative T2-weighted MR images demonstrated intramedullary high signal intensity (IHSI) in 12 cases. IHSI group did not include significantly more Ranawat Grade IIIa cases compared to the remaining 10 cases. In postoperative MR images (nine cases), the regression or disappearance of IHSI was demonstrated in only three cases. CONCLUSIONS: In adult cases with instability due to upper cervical spine anomalies, we acquired favorable clinical outcomes after surgery. Regarding the neurological severity before surgery, there was no relationship with the IHSI on T2-weighted MR image. Moreover, the regression or disappearance of IHSI after surgery was not frequently demonstrated.

Retrospective review of 22 surgically treated adults with XXXX of the upper cervical spine: a clinical and radiological review.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity154 :: ('MESH:D000013', 'Disease') :: ['anomaly', 'congenital anomalies'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological symptoms'] @entity7194 :: ('MESH:D007906', 'Disease') :: ['atlanto-occipital subluxation'] @entity24293 :: ('MESH:C535331', 'Disease') :: ['AAS'] @entity64983 :: ('MESH:C537325', 'Disease') :: ['upper cervical spine anomaly'] @entity9807 :: ('MESH:C538196', 'Disease') :: ['idiopathic atlanto-axial subluxation']
@entity154 :: (MESH:D000013,Disease) :: ['congenital anomalies']
