PURPOSE: @entity463 ( @entity463 ) neurosurgical resection relies on contrast-enhanced MRI-based neuronavigation. However, it is well-known that infiltrating @entity5 extends beyond contrast enhancement. @entity1104 ( @entity1104 ) using @entity2518 ( @entity2518 ) was evaluated to improve extent of resection (EOR) of GBMs. @entity5 metrics were also assessed. PROCEDURES: Thirty @entity1 from a phase II trial evaluating @entity2518 @entity1104 in newly diagnosed @entity463 were assessed. @entity5 were segmented preoperatively to assess morphological features as well as postoperatively to evaluate EOR and @entity41 volume (RTV). RESULTS: Median EOR and RTV were 94.3  % and 0.821  cm(3), respectively. Preoperative surface area to volume ratio and RTV were significantly associated with overall survival, even when controlling for the known survival confounders. CONCLUSIONS: This study supports claims that @entity2518 @entity1104 is helpful at decreasing @entity5 burden and prolonging survival in @entity463 . Moreover, morphological indices are shown to impact both resection and @entity1 survival.

Semi-Automated Volumetric and Morphological Assessment of XXXX Resection with Fluorescence-Guided Surgery.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity41 :: ('MESH:D018365', 'Disease') :: ['residual tumor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumors', 'Preoperative morphological tumor'] @entity2518 :: ('CHEBI:17549', 'Chemical') :: ['5-ALA', '5-aminolevulinic acid'] @entity1104 :: ('MESH:D000267', 'Disease') :: ['Fluorescence-guided surgery', 'FGS'] @entity463 :: ('MESH:D005909', 'Disease') :: ['GBM', 'Glioblastoma']
@entity463 :: (MESH:D005909,Disease) :: ['Glioblastoma']
