AIM: Evidence of improved survival after use of percutaneous coronary intervention (PCI) in elderly @entity1 with @entity1187 ( @entity1187 ) is limited. We assessed the association between PCI and long-term mortality in octogenarians with @entity1187 . METHODS AND RESULTS: We followed 353 consecutive @entity1 aged >= 80 years hospitalized with @entity1187 during 2006-2007. Among them, 182 were treated with PCI, whereas 171 were not. PCI-treated @entity1 were younger and more often male, and had less @entity64 and dependency in activities of daily living, but there were no significant differences in occurrence of @entity6 , @entity1030 , @entity101 , and uncured @entity5 between the two groups. The association between PCI and all-cause mortality was assessed in the overall cohort and a 1:1 matched cohort based on propensity score (PS). In overall cohort, 5-year all-cause mortality was 46.2% and 89.5% in the PCI and non-PCI groups, respectively. Cox regression analysis in overall cohort by adjustment for ten baseline variables showed statistically significant association between PCI and reduced long-term mortality (P<0.001, hazard ratio 0.4, 95% confidence interval [CI] 0.2-0.5). In propensity-matched cohort, 5-year all-cause mortality was 54.9% and 83.1% in the PCI and non-PCI groups, respectively. Kaplan-Meier survival curves and log rank test showed significantly improved mean survival rates (P=0.001): 48 months (95% CI 41-54) for PCI-treated @entity1 versus 35 months (95% CI 29-42) for non-PCI-treated @entity1 . Furthermore, by performing Cox regression analysis, PCI was still associated with reduced long-term mortality (P=0.029, hazard ratio 0.5, 95% CI 0.3-0.9) after adjustment for PS and confounders: age, male sex, @entity73 , uncured @entity5 , left ventricular ejection fraction  <=45%, estimated glomerular filtration rate  <=35 mL/min, ST-segment elevation @entity583 , @entity339 , and medication at discharge with @entity1397 and @entity6817 . CONCLUSION: In octogenarians with @entity1187 , PCI was associated with improved survival from all-cause death over 5 years of follow-up.

XXXX in octogenarians: association between percutaneous coronary intervention and long-term mortality.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndrome'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral regurgitation'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancies'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive deterioration'] @entity1397 :: ('MESH:C055162', 'Chemical') :: ['clopidogrel'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity6817 :: ('D019821', 'Chemical') :: ['statins']
@entity1187 :: (MESH:D054058,Disease) :: ['Acute coronary syndrome']
