INTRODUCTION: The diagnosis of @entity2348 in @entity1 with solid @entity5 can be difficult as both the @entity5 and its treatment can cause symptoms and signs similar to those of @entity281 . Many @entity1 with solid @entity5 therefore receive antibiotic treatment without having a @entity2348 . In this prospective study, we wanted to investigate the value of @entity1904 (PCT) compared with @entity1851 ( @entity1851 ) as an indicator of @entity2348 in adult @entity1 with solid @entity5 . METHODS: A total of 41 @entity1 with solid @entity5 admitted to hospital due to fever or clinical signs of @entity281 had their PCT and @entity1851 levels measured on and during admission. The @entity1 were classified as having a microbio-logically verified @entity281 , a radiologically verified @entity281 or no @entity281 . PCT and @entity1851 were also measured in a control group of 34 out- @entity1 with solid @entity5 , but with no signs of @entity281 . RESULTS: Of the 41 admitted @entity1 , 25 were classified as having an @entity281 (either microbiologically or radioo-gically verified). Among the 25 cases with @entity281 , PCT was within the normal range in 11 cases and only elevated in 14. As nearly half of the @entity1 with @entity281 had PCT within the normal range, PCT is not suited to exclude an @entity281 . @entity1851 was elevated in 20 @entity1 out of the 25. CONCLUSION: PCT within the normal range cannot exclude an @entity281 and does not appear to be superior to @entity1851 to exclude an @entity281 in @entity1 with solid @entity5 . FUNDING: not relevant. TRIAL REGISTRATION: Clinicaltrials.Gov, NCT01227109.

@entity1904 and @entity1851 as markers of XXXX in @entity1 with solid @entity5 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumours', 'tumour'] @entity1904 :: ('MESH:C029100', 'Chemical') :: ['procalcitonin'] @entity2348 :: ('MESH:D001424', 'Disease') :: ['bacterial infections', 'bacterial infection'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'infections'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein', 'CRP']
@entity2348 :: (MESH:D001424,Disease) :: ['bacterial infection']
