BACKGROUND: Management of newborns with interrupted aortic arch (IAA) remains challenging. Associated severe @entity3585 ( @entity3585 ) have often led to increased mortality with neonatal biventricular repair. We review our experience with an alternative approach for this complex surgical problem. METHODS: From May 1991 to June 1999, 28 neonates were treated for IAA. Thirteen of 28 neonates (46%) had type B IAA, @entity1757 ( @entity1757 ) and severe @entity3585 (Z value -2 to -7; mean -5 +/- 1.7). Mean age was 8 days (3 to 23 days old) with average weight of 3.3 kg (2.4 to 4.2 kg). Eight of 13 (62%) had @entity5216 . Ten of 13 (77%) had thymic aplasia and chromosome 22 region qll deletion. All 13 @entity1 were treated initially with a modified Norwood procedure. RESULTS: There were no perioperative @entity204 . Complications included 2 @entity1 with recurrent arch stenosis treated with @entity384 . Two @entity1 had systemic arterial shunt revision. Follow-up ranged from 2 to 99 months old (mean 39 months). There were 2 late @entity204 unrelated to any operation. Nine of 12 @entity1 had a second stage palliation consisting of a bidirectional Glenn shunt. Six @entity1 went on to have biventricular repairs (3 Ross-Konno, 2 Rastelli, 1 @entity1757 closure with LVOT resection). One @entity1 had a modified Fontan operation and 5 @entity1 are awaiting potential biventricular repair. CONCLUSIONS: @entity1 with IAA and severe @entity3585 may be managed by initial Norwood palliation with an excellent outcome likely. This initial "univentricular" approach has enabled eventual successful biventricular repair despite severe @entity3585 .

Successful biventricular repair after initial Norwood operation for interrupted aortic arch with severe XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Children', 'patient'] @entity3585 :: ('MESH:D014694', 'Disease') :: ['left ventricular outflow tract obstruction', 'LVOTO'] @entity384 :: ('MESH:D002311', 'Disease') :: ['balloon dilatation'] @entity1757 :: ('MESH:D006345', 'Disease') :: ['VSD', 'ventricular septal defect'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths'] @entity5216 :: ('MESH:C535555', 'Disease') :: ['anomalous right subclavian artery']
@entity3585 :: (MESH:D014694,Disease) :: ['left ventricular outflow tract obstruction']
