OBJECTIVE: Long-term studies regarding the effect of a structured physical exercise programme (SPEP) during haemodialysis (HD) assessing compliance and clinical benefit are scarce. STUDY DESIGN: A single-centre clinical trial, non-randomised, investigating 46 @entity1 with HD (63.2  16.3   years, male/female 24/22, dialysis vintage 4.4   years) performing an SPEP over 5   years. The SPEP (twice/week for 60   min during haemodialysis) consisted of a combined resistance (8 muscle groups) and endurance (supine bicycle ergometry) training. Exercise intensity was continuously adjusted to improvements of performance testing. Changes in endurance and resistance capacity, physical functioning and quality of life (QoL) were analysed over 1   year in addition to long-term adherence and economics of the programme over 5   years. Average power per training session, maximal strength tests (maximal exercise repetitions/min), three performance-based tests for physical function, SF36 for QoL were assessed in the beginning and every 6   months thereafter. RESULTS: 78% of the @entity1 completed the programme after 1   year and 43% after 5   years. @entity1 were divided-according to adherence to the programme-into three groups: (1) @entity2101 ( @entity2101 , >80% of 104 training sessions within 12   months), (2) moderate adherence (MA, 60-80%), and 3. Low adherence group (LA, <60%)) with @entity2101 and MA evaluated quantitatively. One-year follow-up data revealed significant (p<0.05) improvement for both groups in all measured parameters: exercise capacity ( @entity2101 : 55%, MA: 45%), strength ( @entity2101 : >120%, MA: 40-50%), QoL in three scores of SF36 subscales and physical function in the three tests taken between 11% and 31%. Moreover, a quantitative correlation analysis revealed a close association (r=0.8) between large improvement of endurance capacity and weak physical condition ( @entity2101 ). CONCLUSIONS: The exercise programme described improves physical function significantly and can be integrated into a HD routine with a high long-term adherence.

A structured exercise programme during haemodialysis for XXXX with chronic kidney disease: clinical benefit and long-term adherence.

@entity1 :: ('9606', 'Species') :: ['patients', 'Participants'] @entity2101 :: ('MESH:C538394', 'Disease') :: ['HA', 'high adherence group']
@entity1 :: (9606,Species) :: ['patients']
