AIM: To define the role of small-bowel transit time in the detection rate of significant @entity29 . METHODS: Small-bowel capsule endoscopy records, prospectively collected from 30 participating centers in the Lombardy Registry from October 2011 to December 2013, were included in the study if the clinical indication was obscure @entity360 and the capsule reached the cecum. Based on capsule findings, we created two groups: P2 (significant findings) and P0-1 (normal/negligible findings). Groups were compared for age, gender, small-bowel transit time, type of instrument, modality of capsule performance (outpatients vs inpatients), @entity29 , and center volume. RESULTS: We retrieved and scrutinized 1,433 out of 2,295 capsule endoscopy records (62.4%) fulfilling the inclusion criteria. @entity1 were 67    15 years old, and 815 (57%) were males. In comparison with @entity1 in the P0-1 group, those in the P2 group (n = 776, 54%) were older (P < 0.0001), had a longer small-bowel transit time (P = 0.0015), and were more frequently examined in low-volume centers (P < 0.001). Age and small-bowel transit time were correlated (P < 0.001), with age as the sole independent predictor on multivariable analysis. Findings of the P2 group were @entity1211 (54.5%), inflammatory (23.6%) and protruding (10.4%) lesions, and luminal blood (11.5%). CONCLUSION: In this selected, prospectively collected cohort of small-bowel capsule endoscopy performed for obscure @entity360 , a longer small-bowel transit time was associated with a higher detection rate of significant lesions, along with age and a low center volume, with age serving as an independent predictor.

Implications of small-bowel transit time in the detection rate of capsule endoscopy: A multivariable multicenter study of @entity1 with obscure XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['artero-venous malformations'] @entity360 :: ('MESH:D006471', 'Disease') :: ['gastrointestinal bleeding'] @entity29 :: ('MESH:D015212', 'Disease') :: ['small-bowel lesions', 'bowel cleanliness']
@entity360 :: (MESH:D006471,Disease) :: ['gastrointestinal bleeding']
