BACKGROUND: Our knowledge of thymic @entity5 has largely been derived from small, single-institution series. Recognition of the need for broad collaboration led to the creation of the International Thymic Malignancy Interest Group (ITMIG) and the development of a large, centralized database to advance knowledge of these rare @entity5 . METHODS: A multidisciplinary Database Committee was convened to define a common set of data elements a priori. Retrospective data were solicited from ITMIG members and collated using standardized fields. @entity1 with @entity704 , or @entity6732 were included. RESULTS: Over a 6-month period, 47 institutions spanning 15 countries contributed a total of 6097 cases (mean, 129 [range, 10-1209]). The sex distribution was equal for @entity704 , but there was a greater proportion of @entity1 with @entity704 and @entity6732 (p < 0.0001). Nearly all cases (99%) were treated surgically. WHO type B2 was the most frequent histologic classification among @entity704 , whereas squamous was the most common among @entity704 . In total, 38% of @entity1 with @entity704 had @entity1737 compared with less than or equal to 5% for @entity704 and @entity6732 . Median overall survival was 18.9 years (95% confidence interval [CI], 17.4-20.3) for @entity704 , 6.8 years (95% CI, 5.5-7.9) for @entity704 , and 7.5 years (95% CI, 6.5-8.5) for @entity6732 . CONCLUSIONS: The rapid creation of the ITMIG database demonstrates the feasibility of international collaboration for this rare set of @entity5 and attests to the engagement of its membership. This database represents the largest collective data set ever assembled and provides an unprecedented resource for research of these @entity5 .

Development of the international thymic malignancy interest group international database: an unprecedented resource for the study of a rare group of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity704 :: ('MESH:D013945', 'Disease') :: ['thymoma, thymic carcinoma', 'thymic carcinoma', 'thymoma', 'thymomas', 'thymic carcinomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancies', 'tumors'] @entity1737 :: ('MESH:D009157', 'Disease') :: ['myasthenia gravis'] @entity6732 :: ('MESH:D013953', 'Disease') :: ['thymic carcinoid']
@entity5 :: (MESH:D009369,Disease) :: ['tumors']
