@entity149 ( @entity149 ) is an extranodal @entity1893 arising from and confined to the neuraxis. It represents about 3-4% of all primitive @entity1313 and is mainly located in deep supratentorial regions. A ventricular involvement is quite frequent, but in the vast majority of cases it is secondary to an extension from a subependymal location. Amongst the primary ventricular forms occasionally reported, a choroid plexus origin is extremely rare; to date, only three cases have been described in the English literature. We report the case of a 71-year-old left-handed @entity1 admitted to our department after a progressive 2-week history of @entity911 , motor @entity132 and left @entity1269 . A brain MRI scan displayed an @entity1757 located in the right atrium, about 2.5cm in its major @entity2270 , homogeneously enhancing after @entity2287 administration, surrounded by @entity4 in the homolateral deep hemispheric region; the main diagnostic hypothesis was @entity1653 . She underwent a parieto-occipital craniotomy and a navigation-assisted posterior parietal transcortical approach, achieving complete removal of the @entity1757 originating from the choroid plexus. The histological diagnosis was of high-grade diffuse large @entity1892 . Both an MRI scan of the entire @entity2270 and a thoracic and abdominal CT scan showed no other @entity1313 ; a bone marrow biopsy was normal; a final diagnosis of @entity149 was made. CSF cytological analysis did not show any signs of @entity706 . Adjuvant chemotherapy with @entity1499 was administered, and at the last follow-up (26 months) our @entity1 is clinically and radiologically disease-free. Primary choroid @entity706 is a very rare @entity5 that should be included in the differential diagnosis of @entity2504 . It usually occurs in the lateral ventricles (with a predilection for the atrium) of adult @entity1 (>50 years of age), apparently with a male prevalence. Generally, the radiological picture mimics that of a @entity1653 , despite the fact that @entity1653 usually reach a greater volume before clinical onset. Surgery is almost always necessary to obtain an adequate tissue sample and frequently leads to a radical @entity75 . Low-grade marginal zone B-cell, T-cell and high-grade diffuse large B-cell (present case) forms have been described. With a proper adjuvant therapy a relatively good outcome is observed.

Primary high-grade XXXX of the choroid plexus.

@entity1 :: ('9606', 'Species') :: ['patient', 'woman', 'people'] @entity2504 :: ('MESH:D002551', 'Disease') :: ['intraventricular neoplasms'] @entity132 :: ('MESH:D010468', 'Disease') :: ['speech disturbances'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma dissemination', 'plexus lymphoma'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['neoplastic lesions', 'brain neoplasms'] @entity1269 :: ('MESH:D010291', 'Disease') :: ['hemiparesis'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity2270 :: ('MESH:C566610', 'Disease') :: ['axis', 'craniospinal axis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity149 :: ('MESH:D002493', 'Disease') :: ['PCNSL', 'Primary central nervous system lymphoma', 'primary central nervous system lymphoma'] @entity1757 :: ('MESH:D006345', 'Disease') :: ['intraventricular lesion'] @entity75 :: ('MESH:D001927', 'Disease') :: ['removal of the lesion'] @entity1653 :: ('MESH:D008579', 'Disease') :: ['meningiomas', 'meningioma'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['B-cell lymphoma'] @entity911 :: ('MESH:D003221', 'Disease') :: ['confusion'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['non-Hodgkin lymphoma'] @entity1499 :: ('MESH:D008727', 'Chemical') :: ['methotrexate'] @entity2287 :: ('MESH:D005682', 'Chemical') :: ['gadolinium']
@entity1892 :: (MESH:D016393,Disease) :: ['B-cell lymphoma']
