STUDY OBJECTIVES: Pleural fluid cytology and non-image-guided Abrams or @entity5786 biopsies have sensitivities of approximately 30% for detecting @entity3620 , and thoracoscopic biopsy has a sensitivity of approximately 90%. The difference between these two probably relates to obtaining adequate tissue. The use of immunohistochemical stains allows a firm diagnosis to be made from relatively small samples. This study explores whether percutaneous image-guided cutting needle biopsy (CNB) combined with immunohistochemistry is accurate in diagnosing @entity456 due to @entity2615 . DESIGN: Retrospective review of image-guided CNB of @entity456 performed on consecutive @entity1 over 7 years by a single radiologist. SETTING: Teaching hospital chest radiology department. @entity1 : Twenty-one adult @entity1 with a final diagnosis of @entity3620 were identified from 53 consecutive @entity1 who underwent percutaneous image-guided CNB. All 21 @entity1 had @entity456 identified on contrast-enhanced CT, and all had a final histologic diagnosis of @entity2615 confirmed by postmortem examination or thoracoscopy. INTERVENTIONS: Fourteen-gauge and 18-gauge cutting needles were used. Biopsy guidance was by ultrasound in 6 @entity1 and by CT in 15 @entity1 . MEASUREMENTS AND RESULTS: A correct histologic diagnosis of @entity3620 was made by CNB in 18 @entity1 (86% sensitivity and 100% specificity). Complications included one chest wall @entity1410 and a small hemoptysis. Four @entity1 with a @entity456 thickness of < or = 5 mm underwent biopsy, and all specimens were diagnostic for @entity2615 . CONCLUSIONS: Image-guided percutaneous CNB of @entity456 is a safe procedure, with 86% sensitivity for detecting @entity3620 . Pleural thickening of < or = 5 mm may be successfully sampled.

Percutaneous image-guided cutting needle biopsy of the pleura in the diagnosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity5786 :: ('11316', 'Gene') :: ['Cope'] @entity2615 :: ('MESH:D008654', 'Disease') :: ['mesothelioma'] @entity3620 :: ('MESH:C562839', 'Disease') :: ['malignant mesothelioma'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity456 :: ('MESH:D010995', 'Disease') :: ['pleural', 'pleural thickening']
@entity3620 :: (MESH:C562839,Disease) :: ['malignant mesothelioma']
