@entity28 has been associated with subclinical @entity1002 and increased risk of @entity712 . Few data are available on the relative contribution of @entity1386 distribution and changes in myocardial structure and function. We evaluated the influence of visceral versus subcutaneous abdominal adipose tissue and epicardial fat on LV diastolic function after acute @entity583 . One month after acute @entity583 , 225 consecutive @entity1 were prospectively enrolled and underwent anthropometric evaluation, bioimpedance analysis, detailed echocardiography, and multidetector 64-slice computed tomography scan for quantification of epicardial fat volume (EFV) and of total, subcutaneous and visceral abdominal fat areas. We found a significant association between LV @entity67 parameters and body mass index, fat-mass percentage, and waist-to-height ratio. E' velocity and E/E' ratio were correlated with total and visceral abdominal fat (r  =  -0.27, p <0.001 and r  = 0.21, p <0.01, respectively), but not with subcutaneous fat. After multivariate analysis, increasing EFV was associated with decreased E' velocity (adjusted b  -0.11, 95% confidence interval  -0.19 to  -0.03; p <0.01) and increased E/E' ratio (adjusted b 0.19, 95% confidence interval 0.07 to 0.31, p <0.01). @entity1 with @entity67 showed higher EFV (116.7    67.9  ml vs 93.0    52.3  ml, p  = 0.01), and there was a progressive increase in EFV according to @entity67 grades (p  = 0.001). None of the @entity1386 parameters correlated with ejection fraction or S' velocities. In conclusion, in @entity1 after @entity583 , impaired LV diastolic function was associated with increased @entity1386 , especially with visceral and central fat parameters. Increasing EFV was independently associated with worse LV diastolic function.

Influence of Epicardial and Visceral Fat on Left Ventricular Diastolic and Systolic Functions in @entity1 After XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity28 :: ('MESH:D009765', 'Disease') :: ['Obesity'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity67 :: ('MESH:D018754', 'Disease') :: ['diastolic dysfunction'] @entity1386 :: ('MESH:D018205', 'Disease') :: ['adiposity'] @entity1002 :: ('MESH:D018487', 'Disease') :: ['left ventricular (LV) diastolic dysfunction']
@entity583 :: (MESH:D009203,Disease) :: ['Myocardial Infarction']
