BACKGROUND: The purpose of the present study was the analysis of the trends in case fatality rate of @entity583 ( @entity583 ) in Isfahan, Iran. This analysis was performed based on gender, age groups, and type of @entity583 according to the International Classification of Diseases, version 10, during 2000-2009. METHODS: Disregarding the Multinational Monitoring of Trends and Determinants in @entity65 (MONICA), this cohort study considered all @entity583 events registered between 2000 and 2009 in 13 hospitals in Isfahan. All @entity1 were followed for 28 days. In order to assess the case fatality rate, the Kaplan-Meier analysis, and to compare survival rate, log-rank test were used. Using the Cox regression model, 28 days case fatality hazard ratio (HR) was calculated. RESULTS: In total, 12,900 @entity1 with first @entity583 were entered into the study. Among them, 9307 (72.10%) were @entity1 and 3593 (27.90%) @entity1 . The mean age in all @entity1 increased from 61.36    12.19 in 2000-2001 to 62.15    12.74 in 2008-2009, (P = 0.0070); in @entity1 , from 65.38    10.95 to 67.15    11.72 (P = 0.0200), and in @entity1 , from 59.75    12.29 to 59.84    12.54 (P = 0.0170),. In addition, the 28 days case fatality rate in 2000-2009 had a steady descending trend. Thus, it decreased from 11.20% in 2000-2001 to 07.90% in 2008-2009; in @entity1 , from 09.20% to 06.70%, and in @entity1 , from 16.10% to 10.90%. During the study, HR of case fatality rate in 2000-2001 declined; therefore, in 2002-2003, it was 0.93 [95% confidence interval (CI) = 0.77-1.11], in 2004-2005, 0.88 (95% CI = 0.73-1.04), in 2006-2007, 0.67 (95% CI = 0.56-0.82), and in 2008-2009, 0.69 (95% CI = 0.56-0.82). CONCLUSION: In Isfahan, a reduction was observable in the trend of case fatality rate in both genders and all age groups. Thus, there was a 29.46% reduction in case fatality rate (27.17% in @entity1 , 32.29% in @entity1 ) during the study period.

Trends of 28 days case fatality rate after first XXXX in Isfahan, Iran, from 2000 to 2009.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity583 :: ('MESH:D009203', 'Disease') :: ['AMI', 'acute myocardial infarction'] @entity65 :: ('MESH:D002318', 'Disease') :: ['Cardiovascular Disease']
@entity583 :: (MESH:D009203,Disease) :: ['acute myocardial infarction']
