BACKGROUND: Localized @entity69633 is uncommon and presents clinically as asymptomatic slate gray macules or blue macules resembling @entity4482 . Its histopathologic features are usually similar to those of generalized @entity69633 in which @entity575 granules are found most commonly around the eccrine glands, in the walls of blood vessels, and along elastic fibers. Ochre swollen homogenized collagen bundles resembling @entity27553 have not been previously described. OBJECTIVE: The purpose of this study is to report a series of 5 @entity1 with localized @entity69633 with the histologic feature of " @entity9359 ." In one @entity1 , biopsy was performed on 2 distinct lesions. METHODS: All @entity1 underwent skin biopsies for light microscopy and darkfield microscopy. In two @entity1 , the biopsy specimens were analyzed with a mass spectrophotometer; scanning electron microscopy and energy-dispersive x-ray analysis were performed. In one @entity1 , the biopsy specimen was decolorized with 1% @entity27545 in 20% @entity15451 . RESULTS: All 5 @entity1 presented with the typical clinical and histologic features of localized @entity69633 . Ochre swollen and homogenized collagen bundles were seen in all cases. In addition, light microscopy in 4 cases revealed an ellipsoid black globule within a zone of collagen degeneration. CONCLUSION: The histologic features of localized @entity69633 include swollen and homogenized collagen bundles resembling @entity27553 , " @entity9359 ," which may be more common than previously recognized.

Localized @entity69633 with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity9359 :: ('MESH:C531762', 'Disease') :: ['pseudo-ochronosis'] @entity575 :: ('MESH:D012834', 'Chemical') :: ['silver'] @entity4482 :: ('MESH:D018329', 'Disease') :: ['blue nevi'] @entity69633 :: ('MESH:D001129', 'Disease') :: ['argyria'] @entity15451 :: ('MESH:C017717', 'Chemical') :: ['sodium thiosulfate'] @entity27553 :: ('MESH:D009794', 'Disease') :: ['ochronosis'] @entity27545 :: ('MESH:C028033', 'Chemical') :: ['potassium ferricyanide']
@entity9359 :: (MESH:C531762,Disease) :: ['pseudo-ochronosis']
