OBJECTIVES: The current study examined the relationship between preoperative @entity148 and @entity282 ( @entity20293 ), residual limb @entity158 (RLP), and analgesic medication use in a sample of @entity1 undergoing lower limb amputation. MATERIALS AND METHODS: @entity1 included 69 adults admitted to a large level 1 trauma hospital for lower limb amputation. @entity1 ' average @entity158 and @entity148 during the previous week were assessed before amputation surgery. RLP, @entity20293 , and analgesic medication use were measured on each of the 5 days following amputation surgery. RESULTS: Results of partial-order correlations indicated that greater preoperative @entity148 was significantly associated with greater ratings of average @entity20293 for each of the 5 days following amputation surgery, after controlling for preoperative @entity158 ratings and daily postoperative analgesic medication use. Partial correlation values ranged from 0.30 to 0.62, indicating medium to large effects. @entity148 was also significantly associated with ratings of average RLP only on postoperative day 1, after controlling for preoperative @entity158 ratings and daily postoperative analgesic medication use (r=0.34, P<0.05). Correlations between preoperative @entity148 and daily postoperative analgesic medication dose became nonsignificant when controlling for preamputation and postamputation @entity158 ratings. DISCUSSION: These findings suggest that @entity148 may be a risk factor for acute postamputation @entity20293 and RLP, and indicate that further research to examine these associations is warranted. If replicated, the findings would support research to examine the extent to which modifying preoperative @entity148 yields a reduction in postoperative acute @entity20293 and RLP.

Preoperative State Anxiety, Acute XXXX , and Analgesic Use in @entity1 Undergoing Lower Limb Amputation.

@entity1 :: ('9606', 'Species') :: ['Participants', 'persons'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety', 'Preoperative anxiety'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity282 :: ('MESH:D010149', 'Disease') :: ['acute postoperative phantom limb pain'] @entity20293 :: ('MESH:D010591', 'Disease') :: ['PLP']
@entity282 :: (MESH:D010149,Disease) :: ['Postoperative Pain']
