BACKGROUND: In the course of @entity1569 the loss of scales from the skin surface is observed. This may be related to @entity4977 in epidermis and in blood serum. The aim of the study was to find out if serum lipid profile disturbances occur in psoriatic @entity1 . MATERIAL/METHODS: We studied 26 male and 15 female normolipidemic psoriatic @entity1 , and 29 male and 28 female healthy normolipidemic volunteers. The concentrations of serum pancreatic lipase, total @entity165 , HDL @entity165 , LDL @entity165 , total phospholipids, HDL phospholipids, LDL phospholipids and @entity1674 were measured with enzymatic methods. RESULTS: The study of male @entity1 demonstrated a statistically significant decrease in HDL @entity165 concentration and statistically significant increase in @entity412 concentration. In psoriatic females, we observed a statistically significant decrease in HDL @entity165 concentration, a statistically significant decrease in HDL phospholipid concentration, and a statistically significant increase in pancreatic lipase concentration. In addition, the pancreatic lipase concentration increased insignificantly in the male group. We found lipid profile disturbances in the groups of psoriatic @entity1 , in comparison with the age-, sex-, and BMI-matched control groups. CONCLUSIONS: The obtained results suggest the necessity of careful administration of medicines to psoriatic @entity1 suffering from @entity262 and treated with drugs affecting lipid metabolism.

Activity of serum lipase [EC 3.1.1.3] and the diversity of serum lipid profile in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1569 :: ('MESH:D011565', 'Disease') :: ['psoriasis'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity262 :: ('MESH:D034721', 'Disease') :: ['systemic diseases'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity4977 :: ('MESH:D052439', 'Disease') :: ['lipid disorders'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity1569 :: (MESH:D011565,Disease) :: ['psoriasis']
