AIMS: Ablation of fractionated electrograms (EGMs) has been performed to eliminate areas of slow conduction in @entity955 ( @entity955 ). The @entity28309 suggests that rapidly activating spiral waves perpetuate and maintain @entity955 . This study describes the EGM characteristics of @entity955 rotors, using the novel 64-electrode basket catheter. METHODS AND RESULTS: Twenty-five @entity1 (male n = 16) with @entity955 (paroxysmal n = 10) underwent focal impulse and rotor modulation. A 3.5 mm irrigated-tip ablation catheter was placed at the identified rotor core and EGMs were analysed for amplitude, characteristics (single-EGM, fractionated-EGM, and continuous-EGM), and cycle length over 10 s. A total of 72 rotors were identified [ @entity13678 ( @entity13678 ) = 13, left atrium (LA) = 59]. Seven rotors were excluded from EGM analysis due to location in the pulmonary veins. Single-EGMs were more frequent in the @entity13678 compared with the LA (8 (61.5) vs. 12 (23.1); P < 0.01) and EGM amplitudes were smaller in LA rotors when compared with @entity13678 rotors (0.14 (0.08-0.17) mV vs. 0.19 (0.15-0.29) mV; P = 0.029). In @entity1 with persistent @entity955 , single-EGMs were observed more often in the right-sided rotors compared with left-sided rotors (4 (57.1) vs. 5 (14.3); P = 0.012), and EGM amplitudes were smaller in @entity1 with persistent @entity955 compared with paroxysmal @entity955 (PAF) @entity1 (0.15 (0.09-0.19) mV vs. 0.22 (0.17-0.47) mV; P = 0.03). Furthermore, the prevalence of fractionated- EGMs was higher in @entity1 with persistent @entity955 compared with PAF @entity1 (31/42 (73.8) vs. 9/23 (39.1); P = 0.03). CONCLUSION: There are no characteristic rotor-EGM potentials. Rotor-EGM characteristics are different between the @entity13678 and LA. Although rotors are not associated with abnormal EGMs, @entity28309 in persistent @entity955 were more fractionated with lower amplitudes compared with that in PAF.

Focal impulse and rotor modulation using the novel 64-electrode basket catheter: electrogram characteristics of XXXX rotors.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity13678 :: ('MESH:D064752', 'Disease') :: ['right atrium', 'RA'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation', 'AF'] @entity28309 :: ('MESH:D006933', 'Disease') :: ['rotor hypothesis', 'rotor-EGMs']
@entity1 :: (9606,Species) :: ['human']
