@entity101 is an important manifestation of @entity1252 ( @entity1252 ) but reports of prevalence vary between 20-70% in published reports of adult and pediatric @entity1 . For both @entity1 and adults with @entity1252 , the clinical diagnosis and management of @entity101 has traditionally been based on guidelines developed for the general population. In clinical trials, the criteria used for defining @entity1 with @entity101 are mostly undefined. As a first step towards formally assessing the blood pressure (BP) patterns of @entity1 diagnosed with @entity1252 , 24-hr ambulatory BP monitoring data was analyzed on clinic @entity1 who presented with @entity1556 or stage I @entity101 . In this pediatric @entity1252 cohort, 20% met daytime criteria for a diagnosis of @entity101 . Patterns of BP elevation varied widely with white coat, masked, isolated systolic, and diastolic nocturnal @entity101 all identified. Nocturnal @entity101 was detected in 60% and attenuated nocturnal BP dipping in 90% of both @entity101 and normotensive @entity1252 @entity1 . In @entity1252 @entity1 , the median nighttime systolic and diastolic loads were 25% and 15.5% compared with median daily loads of 12.5% and 11.5%. Daytime and nighttime systolic and diastolic BP load and nocturnal dipping was compared to a control population consisting of 85 non- @entity1252 @entity1 under 21 years old with @entity1556 or stage 1 @entity101 presenting to @entity101 clinic. Median systolic BP dipped 5.3 mmHg in @entity1252 @entity1 compared to 11.9 mmHg in non-lupus ( p-value = 0.001). Median diastolic BP dipped 12.9 mmHg versus 18.5 mmHg in non-lupus ( p-value = 0.003). Patterns of @entity551 in pediatric @entity1252 merit further exploration. @entity1 with or without @entity1252 displaying @entity1556 or stage 1 casual BP measurements had similar rates of @entity101 by ambulatory BP monitoring. However, regardless of BP diagnosis, and independent of kidney involvement, there was an increased proportion with attenuated nocturnal dipping and nocturnal @entity101 in @entity1252 @entity1 .

Nocturnal XXXX and Attenuated Nocturnal Blood Pressure Dipping is Common in Pediatric Lupus.

@entity1 :: ('9606', 'Species') :: ['participants', 'children', 'patients', 'Children'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'hypertensive', 'Hypertension'] @entity1252 :: ('MESH:D008180', 'Disease') :: ['SLE', 'systemic lupus erythematosus'] @entity551 :: ('MESH:D007022', 'Disease') :: ['BP dysregulation'] @entity1556 :: ('MESH:D058246', 'Disease') :: ['prehypertension', 'prehypertensive']
@entity101 :: (MESH:D006973,Disease) :: ['Hypertension']
