OPINION STATEMENT: @entity2758 ( @entity2758 ) pose a risk of morbidity and mortality throughout an affected @entity1 's lifetime. Over the course of a @entity1 's life, the risk of @entity548 is approximately 1-4  % per year, and after an initial @entity548 occurs, this risk may be higher. Other causes of morbidity include @entity410 , @entity10 , or progressive @entity51 . Once an @entity7026 has been discovered, the utility of attempted obliteration or surgical resection compared to the risk of intervention should be entertained. The characteristics of the @entity600 as well as the @entity1 's overall health status contribute to the decision to intervene on these lesions. For small lesions located in superficial areas without high-risk surgical characteristics (low-grade Spetzler-Martin grades), it is reasonable to consider surgical resection. In lesions that pose high-risk of complications from surgical @entity1416 , radiosurgery, or a combination of the two may be reasonable treatment options. Some @entity2758 at traditional high surgical risk may be amenable to partial embolization, allowing initially high-risk lesions to become better candidates for surgical resection. In some @entity1 , particularly those who are older or who have multiple medical comorbidities, the risk of intervention as compared to the annual @entity548 risk may warrant conservative management as opposed to intervention. The overall treatment strategy must be based on @entity1 and @entity7026 characteristics and careful risk-benefit ratio analysis.

Management of brain XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity7026 :: ('MESH:D002538', 'Disease') :: ['AVM'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity2758 :: ('MESH:D001165', 'Disease') :: ['Arteriovenous malformations', 'AVMs'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity1416 :: ('MESH:D020762', 'Disease') :: ['removal, intra-arterial embolization'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformation'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurologic deficits'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headaches']
@entity2758 :: (MESH:D001165,Disease) :: ['arteriovenous malformations']
