BACKGROUND/AIMS: It has been shown that hepatic pedicle clamping is a safe and effective technique to control bleeding during liver resection. A major drawback can be the induction of @entity409 and @entity2979 . METHODOLOGY: This randomized controlled clinical trial compared continuous and intermittent hepatic pedicle clamping during resection of the cirrhotic liver in order to determine which technique is more effective in reducing operative @entity190 and producing less @entity63 . In 18 @entity1 we performed continuous portal triad clamping during liver transection while in 17 @entity1 we performed intermittent clamping. The two groups matched for extent of resection. Serial hepatic function tests were performed on postoperative day 1, 3 and 7. RESULTS: No significant difference was found between the two groups in terms of operative findings. Operative mortality was 5.7% (2 @entity1 ). Six @entity1 (17.3%) had @entity260 . There were no significant differences between the two groups with regard to postoperative liver function tests and coagulation profile. CONCLUSIONS: Continuous and intermittent clamping are both effective in reducing @entity190 during hepatectomy in @entity82 . The two techniques seem to be comparable in terms of @entity63 . Our findings suggest that intermittent portal triad clamping may not be necessary. As this is contrary to the normal expectancy, additional studies may be needed.

Continuous versus intermittent portal triad clamping during hepatectomy in XXXX . Results of a prospective, randomized clinical trial.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic injury'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver ischemia'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity2979 :: ('MESH:D054070', 'Disease') :: ['splanchnic venous stasis']
@entity82 :: (MESH:D005355,Disease) :: ['cirrhosis']
