BACKGROUND: Worldwide, the prevalence of @entity65 such as @entity731 is on the increase. Younger @entity1 may be especially vulnerable owing to their exposure to risk factors such as @entity734 and @entity645 . METHODS: The thoracic aortas of 149 South Africans under the age of 50 years were collected at the Salt River Mortuary, Cape Town, and examined macroscopically and microscopically for evidence of anomalies. The sample comprised predominantly males, and included black, coloured and white individuals. RESULTS: A significantly higher level of macroscopic pathology was found in coloured males, although overall prevalence of pathology in this sample was lower than expected. A positive association was also found between body mass index and vascular pathology in the black and coloured population groups. @entity154 were common and present at high levels, irrespective of age and racial grouping. CONCLUSIONS: The widespread prevalence of @entity154 in all groups suggests that these are normal variations that result from haemodynamic forces. The higher prevalence of @entity731 in coloured males, however, probably results from specific genetic conditions such as hypercholesterolaemia or lifestyle factors such as diet or tik abuse. The findings suggest that coloured individuals may be at increased risk of developing @entity65 .

XXXX in the thoracic aorta: a South African anatomical and histological mortuary study.

@entity1 :: ('9606', 'Species') :: ['people'] @entity154 :: ('MESH:D000013', 'Disease') :: ['microscopic anomalies', 'Microscopic anomalies'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis', 'atherosclerotic lesions'] @entity734 :: ('MESH:D019966', 'Disease') :: ['drug abuse'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease', 'cardiovascular diseases']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerotic lesions']
