OBJECTIVE: To study the significance of @entity1600 ( @entity4298 ) biopsy (SLNB) in determining the extent of axillary dessection for cN0 @entity0 @entity1 . METHODS: In 96 @entity1 with cN0 @entity0 , sentinel lymph nodes identified by patent blue-V or @entity6693 staining were excised for biopsy. @entity1 then received operations for @entity0 including axillary dessection. RESULTS: @entity4298 was identified in 91 @entity1 . The total number of @entity4298 identified was one in 54 cases(59.3%), 2 in 23 cases(25.3%) and > or = 3 in 14 cases(15.4%). In 24 of the 91 @entity1 , @entity4298 was positive for @entity3 . In 13 the 24 @entity1 , only @entity4298 provided evidence of lymph node @entity3 . The sensitivity of @entity4298 biopsy was 87.5%, the specificity was 100%. It had 100% positive predictability and 95.7% negative predictability of lymph node @entity3 . The accuracy rate of intraoperative imprint cytology examination of @entity4298 was 92.1%, with a false negative rate of 10.0% and a false positive rate of 7.1%. The accuracy rate of frozen-section examination of @entity4298 was 98.7% during operation, with a false negative rate of 5.0% but without false positive result. Immunohistochemical assay did not help demonstrate @entity3 in @entity4298 negative on routine pathologic examination. CONCLUSION: The @entity4298 status can generally be a representation of axillary @entity3 , SLNB is useful to determine the extent of axillary dessection in cN0 @entity0 @entity1 . @entity6693 is as effective as patent blue-V in the identification of @entity4298 .

[Clinical significance of @entity1600 biopsy for XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['sentinel lymph node'] @entity6693 :: ('MESH:D008751', 'Chemical') :: ['methylene blue', 'Methylene blue'] @entity4298 :: ('6588', 'Gene') :: ['SLN'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
