Background. @entity414 can acutely activate various inflammatory transcription factors. Since high levels of oxyradicals and lower antioxidant levels in septic @entity1 are believed to result in @entity177 , @entity414 levels could be used as a marker of oxidative stress and poor prognosis in @entity1 with @entity295 . Design. We conducted a prospective cohort study on Medical Intensive Care Unit (MICU) @entity1 and hypothesized that elevated @entity414 in @entity1 with @entity295 is predictive of greater morbidity. The primary end point was the correlation between @entity5052 and the morbidity rate. Secondary end points were @entity810 ( @entity810 ), mortality, @entity649 ( @entity649 ), and duration of stay. Results. We enrolled 144 @entity1 . 54 (37.5%) had the primary end point of @entity5052 . The overall morbidity rate was 85.2%. The probability of having @entity5052 along with @entity810 was 68.5% and without @entity810 was 31.5%. Meanwhile the probability of having a @entity414 value <7   mg/dL along with @entity810 was 18.9% and without @entity810 was 81.1% (p value < 0.0001). Conclusion. We report that elevated @entity414 levels on arrival to the MICU in @entity1 with @entity295 are associated with poor prognosis. These @entity1 are at an increased risk for @entity810 and @entity649 .

@entity5052 : An Early Marker for Severity of Illness in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity649 :: ('MESH:D012128', 'Disease') :: ['Acute Respiratory Distress Syndrome', 'ARDS'] @entity177 :: ('MESH:D051437', 'Disease') :: ['multiorgan failure'] @entity810 :: ('MESH:D058186', 'Disease') :: ['Acute Kidney Injury', 'AKI'] @entity5052 :: ('MESH:D033461', 'Disease') :: ['hyperuricemia'] @entity414 :: ('MESH:D014527', 'Chemical') :: ['Uric acid', 'uric acid']
@entity295 :: (MESH:D018805,Disease) :: ['Sepsis']
