BACKGROUND: The aim of this study was to describe the feasibility, associated morbidity, and efficacy of radical oophorectomy with primary stapled colorectal @entity254 among @entity1 with locally advanced @entity43 with contiguous extension to or encasement of the reproductive organs, pelvic peritoneum, cul-de-sac, and sigmoid colon. STUDY DESIGN: Thirty-one consecutive @entity1 undergoing radical oophorectomy as part of an initial maximal surgical effort for International Federation of Obstetrics and Gynecology (FIGO) stage @entity43 were prospectively collected from October 1, 1997 through November 30, 2001. The surgical technique, associated morbidity, and clinical outcomes are described. RESULTS: The median age was 63 years. All @entity1 had @entity43 : FIGO stage IIIB (6.5%), stage IIIC (64.5%), stage IV (29.0%). Median operating time was 240 minutes (range 165 to 330 minutes), and the median estimated @entity190 was 700 mL (range 300 to 2,900 mL). All @entity1 underwent en bloc rectosigmoid colectomy with primary stapled @entity254 without protective intestinal diversion. There was one (3.2%) anastomotic breakdown requiring reoperation and colostomy. Complete clearance of macroscopic pelvic disease was achieved in all cases. Overall, 87.1% of @entity1 were left with optimal (</=1 cm) residual disease and 61.3% were visibly disease free. There were no postoperative deaths, but major and minor postoperative morbidity occurred in 12.9% and 35.5% of @entity1 , respectively. Blood product transfusion was required in 29.0% of cases. Thirty @entity1 received multiagent @entity902 -based chemotherapy, with a median overall survival time of 39.5 months. CONCLUSIONS: Radical oophorectomy with primary stapled @entity254 is an effective technique for resection of locally advanced @entity43 and contributes significantly to a maximal cytoreductive surgical effort. The associated morbidity is acceptable, and protective intestinal diversion appears unnecessary.

Radical oophorectomy with primary stapled colorectal XXXX for resection of locally advanced @entity43 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity43 :: ('MESH:D010051', 'Disease') :: ['advanced-stage epithelial ovarian cancer', 'ovarian cancer', 'IIIB-IV ovarian cancer'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity902 :: ('MESH:D010984', 'Chemical') :: ['platinum']
@entity254 :: (MESH:C563598,Disease) :: ['anastomosis']
