UNASSIGNED: Our study was designed to analyze prenatal manifestations in @entity1 affected with @entity25938 ( @entity25938 ), in order to define indications of DNA testing in utero. Prenatal features were extracted from a national database and additional data were collected from 16 families contacted through the French association of @entity25937 . We collected results of ultrasound scan (USS) biometrics, presence of @entity600 , and @entity2978 . From the database, increased nuchal translucency was present in 13% of pregnancies, @entity2978 in 52%, @entity8455 and/or @entity4651 in 16%. Of the 16 pregnancies, 81% were complicated by abnormal USS findings. @entity2978 was reported in 67%. Head circumference, biparietal diameter, and abdominal circumference were above the 90th centile in 72%, 83% and, 81% of fetuses, respectively. Contrasting with @entity8455 , femur length was below the 10th centile in 38%. @entity5450 were found in 47% of fetuses. Most @entity25938 fetuses showed a combination of @entity4651 , @entity8455 , and @entity2978 , contrasting with relatively short femora. This growth pattern is also seen in @entity25937 . We suggest that screening for @entity25938 and Costello gene mutations could be proposed in pregnancies showing this unusual pattern of growth parameters.    2015 Wiley Periodicals, Inc.

Prenatal findings in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity25938 :: ('MESH:C535579', 'Disease') :: ['CFCS', 'cardio-facio-cutaneous syndrome'] @entity2978 :: ('MESH:D006831', 'Disease') :: ['Polyhydramnios', 'polyhydramnios'] @entity5450 :: ('MESH:D014570', 'Disease') :: ['Urinary tract abnormalities'] @entity600 :: ('MESH:D000014', 'Disease') :: ['congenital birth defects'] @entity8455 :: ('MESH:D005320', 'Disease') :: ['macrosomia'] @entity4651 :: ('MESH:D058627', 'Disease') :: ['macrocephaly'] @entity25937 :: ('MESH:D056685', 'Disease') :: ['CFC-Costello syndrome', 'Costello syndrome']
@entity25938 :: (MESH:C535579,Disease) :: ['cardio-facio-cutaneous syndrome']
