PURPOSE OF REVIEW: The perioperative management of lung transplantation @entity1 remains a challenge. The most important goal is the prevention or attenuation of @entity177 due to @entity63 and reperfusion, operative @entity130 , and activation of systemic @entity32 ; it significantly influences short-long and long-term outcome. This review focuses on different aspects regarding the management of these high-risk @entity1 . RECENT FINDINGS: The Lung Allocation Score was implemented to estimate the survival benefit from a lung transplant. As scarcity of lung grafts persists new techniques such as the ex-vivo lung perfusion might allow for expanding the criteria and distribution range of donor organs. Thoracic anesthesia for lung transplantation faces the challenge to manage impaired oxygenation, refractory @entity2944 , and severe @entity120 in order to attenuate the risk of @entity177 . Further, lung protective ventilator strategies to prevent postoperative @entity647 might have an impact on outcome. This includes extracorporeal circulation therapy as rapid advances in this field open up new possibilities. Recent findings suggest that particular attention should be paid to neurocognitive outcome. SUMMARY: There is evidence that important key strategies improve outcome after lung transplantation. An update on the substantial challenges in anesthesia comprises ventilator strategy and the use of extracorporeal circulation to minimize @entity32 associated with @entity177 .

Lung transplantation: from the procedure to managing XXXX with lung transplantation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity2944 :: ('MESH:D006935', 'Disease') :: ['hypercapnia'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia'] @entity120 :: ('MESH:D006976', 'Disease') :: ['pulmonary hypertension'] @entity177 :: ('MESH:D051437', 'Disease') :: ['primary graft failure'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma'] @entity647 :: ('MESH:D055371', 'Disease') :: ['acute lung injury']
@entity1 :: (9606,Species) :: ['patients']
