BACKGROUND: Transversus abdominis plane (TAP) block and local anaesthetic wound infiltration can provide effective @entity158 relief at the wound site after surgery. However, the relative efficacy of two techniques for @entity86 remains controversial. METHODS: We searched PUBMED, EMBASE and CENTRAL databases for randomized controlled trials (RCTs) comparing TAP block with wound infiltration for @entity158 relief after surgery. The primary outcomes were @entity158 scores at rest and on movement at 1, 8 and 24 hours postoperatively and cumulative @entity1286 consumption over 24 hours. The secondary outcomes were time to first rescue analgesic, number of rescue analgesic use and opioids-related side-effects. RESULTS: Nine RCTs with a total of 500 @entity1 were included. TAP block was associated with significant lower rest and @entity158 scores at 8 hour [MD = -1.08, 95% CI (-1.89-0.26), P = 0.009] and 24 hour [MD = -0.83, 95% CI (-1.60, -0.06), P = 0.03] postoperatively than wound infiltration, but no significant difference was found at 1 hour [MD = -0.94, 95% CI (-1.97, 0.09), P = 0.08] postoperatively. In adults, TAP block significantly reduced 24-hour overall @entity1286 consumption by 3.85 mg [MD = -3.85, 95% CI (-7.47, -0.22), P = 0.04] compared with wound infiltration. Subgroup analysis showed that adults received TAP block appeared to have lower @entity158 scores at 24 hour than @entity1 (P = 0.008). CONCLUSION: TAP block provides superior @entity1337 compared with wound infiltration in the setting of a multimodal analgesic regimen. Subgroup analysis indicated that adults may have benefits additional to the analgesic effect than @entity1 .

Transversus abdominis plane block versus local anaesthetic wound infiltration for XXXX : A systematic review and meta-analysis.

@entity1 :: ('9606', 'Species') :: ['participants', 'children'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative analgesia'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['rest pain', 'pain', 'dynamic pain']
@entity86 :: (MESH:D019106,Disease) :: ['postoperative analgesia']
