Long term outcome and prognosis factors of @entity1 with @entity3 were evaluated on 29 observations from 3 centres reviewed retrospectively. Twenty-nine @entity1 less than 18 years old were treated from 1990 to 1998. Only 29 of these @entity1 had received similar treatments associating chemotherapy and surgery, adapted according to histological and clinical response to treatment, as recommended by the SFOP. Overall survival at five years was 26%, and disease free survival 14%. Eight @entity1 are alive, four in first complete remission (CR) and four in second CR. Three of the four @entity1 alive in first CR had bone @entity3 at diagnosis. On univariate analysis, factors predicting survival are: the numbers of organs affected by metastatic lesions, the number of lung nodules and the type of surgery. This is, to our knowledge, the first report of long term survivors with bone @entity3 at diagnosis. @entity3 prognosis remain poor. A randomised study would help to define the best possible treatment for this disease.

[ XXXX : prognosis factors and treatment].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic osteosarcoma', 'Metastatic osteosarcoma', 'metastases']
@entity3 :: (MESH:D009362,Disease) :: ['Metastatic osteosarcoma']
