PURPOSE: To determine whether a significant smaller volume of the affected globe, compared with that of the normal globe, is an additional feature of @entity8038 . MATERIALS AND METHODS: Ocular globe volume was assessed in 13 @entity1 (11 @entity1 , two @entity1 ; age range, 0.6-14 years; mean age, 4.1 years) with @entity8038 and in 18 (eight @entity1 , 10 @entity1 ; age range, 0.5-12 years; mean age, 3.6 years) with @entity995 . Orbital computed tomographic scans were available for all @entity1 ; magnetic resonance images were available for 11 @entity1 -seven with @entity8038 and four with @entity995 . For volume estimation, anteroposterior and equatorial diameters of ocular globes were measured. Statistical analysis was conducted with univariate and multivariate methods. RESULTS: In @entity1 with @entity8038 , the mean volume of the affected globe was 4,877.03 mm(3) (range, 2,951.47-6,284.70 mm(3)) and that of the normal globe, 6,018.00 mm(3) (range, 4,062.32-7,509.26 mm(3)). In @entity1 with @entity995 , the mean volume of the affected globe was 4,557.06 mm(3) (range, 1,612.01-7,463.00 mm(3)) and that of the normal globe, 4,402.11 mm(3) (range, 1,360.46- 7,463.00 mm(3)). The @entity8038 population had a significantly smaller volume of the affected globe (z = -3.1009; P =.002); the @entity995 population did not have a statistically significant trend toward a bigger affected globe volume (z = -1.7064; P =.088). The difference between the affected globe volume and the normal globe volume in @entity1 with @entity8038 was the only significant independent variable (P =.005). CONCLUSION: A significantly smaller volume of the affected globe is an additional feature of @entity8038 .

XXXX : smaller volume of the affected globe.

@entity1 :: ('9606', 'Species') :: ['children', 'girls', 'boys'] @entity8038 :: ('MESH:D058456', 'Disease') :: ['Coats disease'] @entity995 :: ('MESH:D012175', 'Disease') :: ['retinoblastoma', 'unilateral retinoblastoma']
@entity8038 :: (MESH:D058456,Disease) :: ['Coats disease']
