BACKGROUND: The survival of @entity1 with @entity320 is poor. The response rates for chemotherapy and immunotherapy have been low, with no real improvement in survival. We reviewed the results of surgical resection. METHODS: We performed a retrospective review of the medical records of all @entity1 who underwent resection of metastases from melanoma from 1979 to 1994. RESULTS: There were 77 @entity1 (44 @entity1 , 33 @entity1 , mean age 51 years). @entity3 were resected from soft tissue (n = 28), abdominal viscera (n = 22), lung (n = 15), and brain (n = 12). Forty-four @entity1 had complete resections, and 33 had incomplete resections. Sixty-five @entity1 had solitary lesions and 12 had @entity75 resected. The overall 5-year survival rate was 10%. @entity1 with solitary lesions had a 5-year survival rate of 12%, compared with 0% for @entity1 with @entity75 (P = 0.01). @entity1 with complete resection had a 5-year survival rate of 15%, compared with 4% for @entity1 with incomplete resection (P < 0.001). @entity1 with complete resection of solitary lesions had a 5-year survival of 18%. There was no difference in survival between synchronous and metachronous resection. Gender, primary site, disease-free interval, and metastatic site had no impact on survival rates. CONCLUSIONS: We conclude that @entity1 with @entity320 should be resected for (1) relief of symptoms such as obstruction and @entity548 , (2) solitary lesions that can be completely resected, (3) serial lesions that can be completely resected, and (4) selected cases that can be rendered macroscopically free of disease. Surgical resection is superior to any other available therapy for @entity320 .

Surgical treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity75 :: ('MESH:D001927', 'Disease') :: ['multiple lesions'] @entity3 :: ('MESH:D009362', 'Disease') :: ['Metastases'] @entity320 :: ('MESH:D008545', 'Disease') :: ['metastatic melanoma']
@entity320 :: (MESH:D008545,Disease) :: ['metastatic melanoma']
