A male neonate presented with a high white cell count, an 11q23 translocation, and @entity1778 . He was treated at 3 days of age with intensive combination chemotherapy after progressing despite exchange transfusions. The @entity1 achieved complete remission at 28 days of age. Therapy was completed at the age of 6 months. At the time of this report, the @entity1 is 17 months old and remains in remission. Twenty-nine @entity1 with @entity3052 were also reviewed. Twenty of these @entity1 received varying therapies. Ten of the treated @entity1 achieved complete remission; two died of @entity137 ; and eight died of progressive disease. Two @entity1 had a translocation affecting 11q23. @entity1778 is a rare and usually fatal condition in @entity1 without Down syndrome. The @entity1 reported here shows that survival may be achieved with very intensive chemotherapy plus supportive care, despite extremely high white blood cell counts and unfavorable translocation.

XXXX : successful treatment of a newborn with t(5;11)(q31;q23).

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['M5b leukemia', 'Congenital leukemia'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['congenital acute myeloid leukemia']
@entity1778 :: (MESH:D007938,Disease) :: ['Congenital leukemia']
