BACKGROUND: The international consensus guidelines for the management of @entity4929 ( @entity4929 ) of the pancreas were revised in 2012 Tanaka (Pancreatology 12(3):183-197, 2012), making the indications for operation less aggressive. Therefore, the number of @entity1126 ( @entity1126 ) @entity1 requiring follow-up care is expected to increase in the future. METHODS: The aim of this study was to identify risk factors for @entity5 in @entity1126 @entity1 during the follow-up period. This study included 47 @entity1126 @entity1 without a mural nodule (MN) at the time of initial diagnosis and who subsequently underwent resection after a follow-up period of more than 3  months. Data for the @entity1 were reviewed retrospectively, and the clinicopathological factors were investigated. RESULTS: In a univariate analysis, age (   65  years), an increase in the main pancreatic duct (MPD) diameter, the MPD diameter at resection (   5  mm), and the occurrence of MN were significantly associated with @entity5 . The occurrence of MN was the only significant factor in a multivariate analysis. In addition, 7 of the 17 @entity1 (41.2  %) who only exhibited an increase in the cyst diameter during the follow-up period were diagnosed as having @entity5 . All 6 @entity1 who exhibited an increase in the cyst diameter of 100  % or more were diagnosed as having @entity189 . CONCLUSIONS: During the follow-up period, the incidence of @entity5 was higher among @entity1 with BD-IPMNs and the occurrence of MN, an increase in the @entity14501 diameter, or an increase ratio of 100  % or more in cyst diameter than the others; resection was recommended for these @entity1 .

Risk Factors for Malignancy in XXXX of the Pancreas During the Follow-Up Period.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4929 :: ('MESH:C565310', 'Disease') :: ['intraductal papillary mucinous neoplasm', 'IPMN'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancy', 'malignancies'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity1126 :: ('MESH:D001650', 'Disease') :: ['branch duct-type IPMN', 'BD-IPMN'] @entity14501 :: ('CHEBI:62995', 'Chemical') :: ['MPD']
@entity4929 :: (MESH:C565310,Disease) :: ['Branched-Type Intraductal Papillary Mucinous Neoplasms']
