PURPOSE: The aim of this study was to evaluate the diagnostic accuracy and clinical value of preoperative sonographic detection of multifocality in @entity0 . METHODS: Between November 1, 1999, and November 30, 2000, we prospectively compared the sonographic and histopathologic findings for all nodules measuring 1 cm or less in the longest dimension on sonography in 19 consecutive @entity1 diagnosed with @entity0 . For each nodule, the final histopathologic diagnosis, size, and, in cases of nodules in the same breast as the @entity75 , the distance from that lesion were evaluated. RESULTS: The 19 @entity1 examined, all of whom were @entity1 , had a mean age of 42.1 years (range, 28-62 years). Thirty nodules were detected on sonography: 15 @entity1 had a total of 24 nodules in the ipsilateral breast, 2 @entity1 each had 1 nodule in the contralateral breast, and 2 @entity1 each had 1 nodule in the ipsilateral breast and 1 nodule in the contralateral breast, for a total of 26 ipsilateral and 4 contralateral nodules. Of the 30 lesions, 20 (67%) appeared to be malignant (ie, satellite nodules) on sonography. Histopathologic examination showed that of these @entity5 , 15 (75%), which were found in 10 @entity1 , were malignant and 5 (25%), which were found in 4 @entity1 , were benign. For 7 (70%) of the 10 @entity1 whose nodules appeared malignant on sonography, the initial treatment plan was changed because of the sonographic findings. Ten lesions were assessed as benign on sonography; histopathologic examination confirmed that all 10 were benign. Sonography had a sensitivity of 100%, a specificity of 67%, a positive predictive value of 75%, a negative predictive value of 100%, and an accuracy rate of 83%. The mean size of the nodules was 0.8 cm (range, 0.3-1.4 cm). The mean distance of the 26 ipsilateral nodules from the @entity75 was 1.8 cm (range, 0.5-6 cm). CONCLUSIONS: Preoperative sonography is accurate and reliable for detecting small satellite nodules and can have an important role in the preoperative evaluation of @entity1 for whom breast-conserving surgery is planned.

Sonographic detection of multifocality in XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant-looking lesions'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesion'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast carcinoma']
@entity0 :: (MESH:D001943,Disease) :: ['breast carcinoma']
