GOALS: To test the hypothesis that the use of a low-residue breakfast (LRB) the day prior to colonoscopy was not inferior to consuming @entity16488 ( @entity16488 ) in @entity1 undergoing outpatient colonoscopy with a @entity968 ( @entity970 ) bowel preparation. BACKGROUND: Optimal colon cleansing is essential for complete visualisation of the mucosa during colonoscopy. Few studies have examined the effect of diet on the quality of bowel cleansing or tolerance in @entity1 using a @entity970 bowel preparation for colonoscopy. METHODS: Randomised, single-blinded non-inferiority trial. Adult @entity1 scheduled for outpatient colonoscopy with @entity970 solution were randomised to an LRB followed by clear fluids or @entity16488 using either a traditional or split-dose @entity970 solution for bowel preparation. The primary outcome was colon cleansing based on the Ottawa Bowel Preparation Score (OBPS). RESULTS: On an intention-to-treat (ITT) basis, a total of 109 and 105 @entity1 were included in the @entity16488 and LRB arms, respectively, with 116 and 98 @entity1 , respectively, for the per-protocol (PP) analysis. Although there was no difference in the mean total OBPS between the @entity16488 or LRB arms in either the ITT or PP analysis, the threshold for non-inferiority was not met. @entity1 acceptance of the regimens was higher in the LRB arm than in the @entity16488 arm in the ITT and PP analyses. CONCLUSIONS: This study failed to show the non-inferiority of an LRB in @entity1 receiving bowel preparation with a @entity970 -based solution. A @entity16488 should be prescribed when using a @entity970 bowel preparation. TRIAL REGISTRATION NUMBER: This trial is registered at ClinicalTrials.gov (NCT01454388).

Low-residue breakfast during the preparation for colonoscopy using a XXXX electrolyte solution: a randomised non-inferiority trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity16488 :: ('MESH:D018262', 'Disease') :: ['clear fluids alone', 'CFD'] @entity970 :: ('CHEBI:46793', 'Chemical') :: ['PEG'] @entity968 :: ('MESH:D011092', 'Chemical') :: ['polyethylene glycol']
@entity968 :: (MESH:D011092,Chemical) :: ['polyethylene glycol']
