PURPOSE: Excision and biliary reconstruction using a Roux loop is the current standard for @entity600 ( @entity600 ). This is un-physiological, delivering bile beyond the duodenum and excluding a significant length of the jejunum from intestinal absorption. We investigated whether this had an effect on post-operative growth. METHODS: Retrospective case-note analysis of @entity1 surgically treated for @entity600 . Growth variables were converted to standard deviation scores (SDS) and compared against population norms. P  <  0.05 was significant. RESULTS: From 1994 to 2014, 135 @entity1 (<16  years) were identified. Median age at surgery was 3.3 (IQR 1.5-7) years. Morphology included: type 1 Cystic (n  =  54, 40  %), type 1 Fusiform (n  =  58, 43  %) and type 4 (intra and extra-hepatic) (n  =  22, 16  %). There was pre-operative @entity851 [median weight SDS  =  -0.4 (-1.2  -  0.4), P  =  0.0004] with a similar trend for height [SDS  =  -0.38 (-1.2  -  0.5), P  =  0.08)]. This correlated with presentation @entity648 (r s   =  -0.24, P  =  0.004), GGT (r s   =  -0.27, P  =  0.002) and AST (r s   =  -0.27, P  =  0.002) but not morphology (P  =  0.82) or presentation (P  =  0.4). Median follow-up was 1.9 (0.6-4.7) years, during which time both height (P  =  0.73) and weight (P  =  0.45) reverted to normal. CONCLUSION: This is the first report of growth in @entity1 with @entity600 following a Roux-loop reconstruction and showed pre-operative @entity851 probably attributed to a period of @entity253 but catch-up growth when corrected.

Growth in XXXX with choledochal malformations: effect of the Roux loop.

@entity1 :: ('9606', 'Species') :: ['children'] @entity851 :: ('MESH:D006130', 'Disease') :: ['growth failure'] @entity648 :: ('MESH:D001663', 'Chemical') :: ['bilirubin'] @entity600 :: ('MESH:D000014', 'Disease') :: ['CM', 'choledochal malformation'] @entity253 :: ('MESH:D001660', 'Disease') :: ['biliary obstruction']
@entity1 :: (9606,Species) :: ['children']
