@entity384 ( @entity384 ) is a noninvasive technique used to measure conduit artery vascular function. Limited information is available on normative @entity384 values in healthy @entity1 and adolescents. The objective of this study was to assess relationships between age and sex with @entity384 across childhood and adolescence. Nine hundred and seventy-eight asymptomatic @entity1 (12    3 yr, range 6-18 yr, 530 male) underwent ultrasonic brachial artery assessment before and after 5 min of forearm @entity63 . Sex differences in @entity384 and baseline artery diameter were assessed using mixed linear models. Baseline artery diameter was smaller in females than males [2.96 mm (95% CI: 2.92-3.00) vs. 3.24 mm (3.19-3.28), P < 0.001] and increased with age across the cohort (P < 0.001). Diameter increased between ages 6 and 17 yr in males [from 2.81 mm (2.63, 3.00) to 3.91 mm (3.68, 4.14)] but plateaued at age 12 yr in females. Males had a lower @entity384 [7.62% (7.33-7.91) vs. 8.31% (7.95-8.66), P = 0.024], specifically at ages 17 and 18 yr. There was a significant effect of age on @entity384 (P = 0.023), with a reduction in @entity384 apparent postpuberty in males. In conclusion, the brachial artery increases structurally with age in both sexes; however, there are sex differences in the timing and rate of growth, in line with typical sex-specific adolescent growth patterns. Males have a lower @entity384 than females, and @entity384 appears to decline with age; however, these findings are driven by reductions in @entity384 as males near maturity. The use of age- and sex-specific @entity384 data may therefore not be pertinent in childhood and adolescence.

Age and sex relationship with flow-mediated dilation in healthy XXXX and adolescents.

@entity1 :: ('9606', 'Species') :: ['children'] @entity384 :: ('MESH:D002311', 'Disease') :: ['FMD', 'Flow-mediated dilation'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia']
@entity1 :: (9606,Species) :: ['children']
