BACKGROUND: @entity3001 has been described as one possible cause of sudden @entity1274 and @entity528 . The necessity of serological diagnosis and its therapeutic consequences have been discussed controversially. @entity1 AND METHODS: 344 @entity1 with acute @entity1274 and 66 @entity1 with @entity528 were examined in retrospect. By means of ELISA (Enzygnost Borreliosis, Dade Behring Marburg) the specific prevalences of IgG- and IgM-antibodies against @entity12732 in serum were evaluated. The frequency of seroprevalences for both diseases were compared to those given in the literature. Neurootological findings of the seropositive @entity1 were compared with those of seronegative and analysed statistically. RESULTS: 15.7 % of the @entity1 with sudden @entity1274 had positive levels of IgG-antibodies. IgM-titers were elevated in 4.7 % of the @entity1 . The seroprevalences for IgM and IgG were above those described by other investigators for the healthy population. @entity1 with positive IgM-antibodies showed more often low frequency @entity393 than IgG-positive @entity1 . 18.2 % of the @entity1 with @entity528 had IgG- and 1.5 % IgM-antibodies against @entity12732 . Whereas IgG occurred more often than known for the healthy population, IgM was within the limit for the healthy population. The seropositive group did not show any remarkable neurootological signs compared with the seronegative group. CONCLUSIONS: Because of the elevated seroprevalences @entity12732 may be one possible but very rare cause of sudden @entity1274 and @entity528 . Low frequency @entity393 may be a sign for an infection with @entity12732 as an etiological factor especially in combination with seropositive titers. In case of the presence of IgM-antibodies, patients may be treated with oral antibiotics ( @entity47931 , Cefuroxim). In @entity1 with @entity528 a @entity9144 should be excluded by means of lumbar puncture.

[ @entity3001 --a reason for sudden XXXX and @entity528 ?].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity47931 :: ('CHEBI:50845', 'Chemical') :: ['Doxycyclin'] @entity3001 :: ('MESH:D008193', 'Disease') :: ['Lyme disease'] @entity9144 :: ('MESH:D020852', 'Disease') :: ['neuroborreliosis'] @entity12732 :: ('MESH:D001899', 'Disease') :: ['Borrelia', 'Borrelia infections', 'borrelia'] @entity1274 :: ('MESH:D006319', 'Disease') :: ['sensorineural hearing loss'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss'] @entity528 :: ('MESH:D009410', 'Disease') :: ['neuronitis vestibularis', 'vestibular neuronitis']
@entity1274 :: (MESH:D006319,Disease) :: ['sensorineural hearing loss']
