UNASSIGNED: Objectives: To assess the magnitude of the disparity in @entity79 ( @entity79 ) Z-scores generated by different reference databases and to evaluate whether the relationship between @entity79 Z-scores and @entity174 ( @entity174 ) varies by choice of database. @entity1 and Design: @entity1 with @entity1778 underwent @entity79 by cross-calibrated dual energy x-ray absorptiometry, with Z-scores generated according to Hologic and Lunar databases. @entity174 were assessed by the Genant method on spine radiographs. Logistic regression was used to assess the association between fractures and @entity79 Z-scores. Net reclassification improvement (NRI) and area under the receiver operating characteristic curve (AUC) were calculated to assess the predictive accuracy of @entity79 Z-scores for @entity174 . Results: For the 186 @entity1 from 0-18 years of age, 6 different age ranges were studied. The Z-scores generated for the 0 to 18 group were highly correlated (r >=  0.90), but the proportion of @entity1 with @entity79 Z-scores  <= -2.0 among those with @entity174 varied substantially (from 38 to 66%). Odds ratios (OR) for the association between @entity79 Z-score and @entity174 were similar regardless of database (OR = 1.92, 95% confidence interval (CI): 1.44, 2.56 to OR = 2.70, 95% CI: 1.70, 4.28). AUC and NRI ranged from 0.71 to 0.75 and -0.15 to 0.07 respectively. Conclusions: While the use of a @entity79 Z-score threshold as part of the definition of @entity170 in a @entity1 with @entity174 does not appear valid, the study of relationships between @entity1555 and @entity174 is valid regardless of the @entity1555 database that is used.

The Choice of Normative Pediatric Reference Database Changes Spine Bone Mineral Density Z-scores But Not The Relationship of Bone Mineral Density With Prevalent XXXX .

@entity1 :: ('9606', 'Species') :: ['child', 'children', 'Patients', 'Children'] @entity174 :: ('MESH:D050723', 'Disease') :: ['vertebral fractures', 'VF'] @entity170 :: ('MESH:D010024', 'Disease') :: ['osteoporosis'] @entity79 :: ('MESH:D001847', 'Disease') :: ['LSBMD', 'lumbar spine bone mineral density'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['leukemia'] @entity1555 :: ('MESH:D020388', 'Disease') :: ['BMD']
@entity174 :: (MESH:D050723,Disease) :: ['Vertebral Fractures']
