OBJECTIVE: The aortic distensibility index, as a measure of vascular function, can serve as a marker of @entity453 severity. This study explores the feasibility of using the non-invasively measured index as an indicator of severity of @entity3979 . METHODS: One hundred @entity1 with normal left ventricular systolic function were prospectively enrolled. They were subjected to assessment of aortic distensibility using computed tomographic angiography and transthoracic echocardiography. @entity453 severity and coronary artery @entity460 score were assessed. RESULTS: The mean age of the whole study cohort was 58 +/- 9 years, 63 (63%) being males. A significant inverse correlation was found between aortic distensibility measured using computed tomographic angiography and @entity1 ' age, systolic blood pressure, coronary artery @entity460 score and severity of @entity453 ( @entity850 ). However, there was no statistical correlation with the number of diseased coronary arteries. A strong direct correlation was recorded upon comparing aortic distensibility index values obtained using computed tomographic angiography and transthoracic echocardiography (r=0.325, P=0.004). Receiver operating characteristic curve analysis revealed that an echocardiography-derived aortic distensibility index value of 6.65% is associated with significant (50% luminal stenosis) @entity453 with a sensitivity of 83%, specificity of 93%, positive predictive value of 97% and negative predictive value of 65%. CONCLUSION: Non-invasive assessment of aortic distensibility indices is a feasible procedure to predict significant @entity453 . Lower values are associated with significant obstructive @entity453 and high coronary artery @entity460 score.

Using aortic distensibility index to detect XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3979 :: ('MESH:D023921', 'Disease') :: ['coronary stenosis'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity453 :: ('MESH:D003324', 'Disease') :: ['Coronary artery disease', 'coronary artery disease', 'atherosclerotic coronary artery disease'] @entity850 :: ('MESH:D003251', 'Disease') :: ['percent luminal stenosis']
@entity3979 :: (MESH:D023921,Disease) :: ['coronary stenosis']
