BACKGROUND/AIMS: The present study was conducted to determine if @entity3883 promotes bacterial translocation and to evaluate the changes in hepatic histopathology in @entity1 with @entity253 . METHODOLOGY: Between January 1996 and January 1998, 19 @entity1 treated for @entity253 were studied. Fourteen @entity1 with symptomatic @entity2963 were taken as the control group. @entity1 characteristics, preoperative and post-operative laboratory tests with an interval of 7 days were recorded. In all @entity1 , bile and mesenteric lymph nodes samples were taken for bacterial growth and histopathologic changes were studied on the liver excised during surgery. RESULTS: In the control group, bacterial growth was observed in the bile and mesenteric lymph nodes cultures in one (7.1%) and two @entity1 (14.3%), respectively. In the study group, 8 @entity1 (42%) had positive bile cultures and 12 @entity1 (63.2%) had positive mesenteric lymph nodes cultures, respectively. Histopathologic examination of the liver revealed significant increase in the rate of periductal and portal @entity82 in the @entity1087 @entity1 , compared with control group (p < 0.001). @entity260 in the study group were wound @entity281 (3 cases), @entity177 (2 cases), @entity649 (1 cases) and intraabdominal abscess (1 cases). In the control group, one @entity1 had wound @entity281 and one had @entity891 . Two @entity1 with @entity1087 died of @entity881 and @entity1576 . In long-term follow-up (mean 17 months), when @entity991 and @entity2835 developed in one @entity1 each in the study group, no long-term complication occurred in the control group. CONCLUSIONS: Our clinical results demonstrate that extrahepatic @entity253 promotes bacterial translocation and this process is an important cause of morbidity and mortality in @entity1 with @entity1087 . Also, @entity3883 subsequently leads to significant functional and morphological @entity409 .

Short and long-term effects of bacterial translocation due to @entity3883 on XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patient'] @entity3883 :: ('MESH:D041781', 'Disease') :: ['obstructive jaundice'] @entity2835 :: ('MESH:D008105', 'Disease') :: ['secondary biliary cirrhosis'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice', 'jaundiced'] @entity649 :: ('MESH:D012128', 'Disease') :: ['ARDS'] @entity991 :: ('MESH:D015209', 'Disease') :: ['sclerosing cholangitis'] @entity409 :: ('MESH:D008107', 'Disease') :: ['damage in the liver'] @entity260 :: ('MESH:D011183', 'Disease') :: ['Postoperative complications'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity2963 :: ('MESH:D002769', 'Disease') :: ['cholelithiasis'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity891 :: ('MESH:D001261', 'Disease') :: ['atelectasis'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory failure'] @entity881 :: ('MESH:D009102', 'Disease') :: ['multiple organ failure'] @entity253 :: ('MESH:D001660', 'Disease') :: ['benign biliary obstruction', 'biliary obstruction']
@entity409 :: (MESH:D008107,Disease) :: ['liver damage']
