PURPOSE: Stereotactic ablative body radiation therapy for primary @entity703 treatment relies on motion management that can quantify both the trajectory of kidney motion and stabilize the @entity1 . A prospective ethics-approved clinical trial of stereotactic treatment to primary kidney targets was conducted at our institution. Our aim was to report on specific @entity703 motion and the inter- and intrafraction motion as seen on treatment. METHODS AND MATERIALS: @entity1 with @entity5 size <5 cm received a dose of 26 Gy in 1 fraction and those with @entity5 size >= 5 cm received 42 Gy in 3 fractions. All @entity1 underwent a 4-dimensional computed tomography planning scan, immobilized in a dual-vacuum system. A conventional linear accelerator cone beam computed tomography scan was used for pre-, mid-, and posttreatment imaging to verify target position. RESULTS: Between July 2012 and October 2014, 33 targets from 32 consecutive @entity1 (24 males/8 females) were treated. Seventeen targets were prescribed 26 Gy/1 fraction and the remaining 16 targets received 42 Gy/3 fractions. Kidney motion at each of the poles was not affected by the presence of @entity5 (P = .875), nor was the motion statistically different from the corresponding contralateral kidney pole (P = .909). The mean 3-dimensional displacement of the target at mid- and posttreatment was 1.3 mm (standard deviation    1.6) and 1.0 mm (standard deviation    1.3), respectively. The maximum displacement in any direction for 95% of the fractions at mid- and posttreatment was  <=3 mm. CONCLUSION: In summary, stereotactic ablative body radiation therapy of primary kidney targets can be accurately delivered on a conventional linear accelerator with protocol that has minimal intrafractional target motion.

Image guidance and stabilization for stereotactic ablative body radiation therapy (SABR) treatment of primary XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity703 :: ('MESH:D007680', 'Disease') :: ['kidney tumor', 'kidney cancer']
@entity703 :: (MESH:D007680,Disease) :: ['kidney cancer']
