1. The light fraction of the proteoglycan of @entity291 nasal cartilage was split by treatment with 0.1m- @entity5836 in @entity1324 . The products were separated by gel filtration on 4% agarose and two retarded fractions were detected and isolated. These two fractions were found to have a Stokes radius of 134 and 47 A respectively, as determined by calibration of the column against proteins of known hydrodynamic volumes. 2. The 47 A fraction had a protein content of 4% and a @entity4823 / @entity11485 ratio 1:23. The 134 A fraction had a protein content of 20% and a @entity4823 / @entity11485 ratio 1:4.8. 3. The results of the viscometric studies on both fractions suggested that the 134 A fraction alone exhibited the property of undergoing reversible pH-dependent aggregation with a transition point at pH4.9. 4. It was concluded that these fractions could represent subunits of the native cartilage proteoglycan.

The subunits of chemically treated proteoglycan isolated from XXXX nasal cartilage.

@entity5836 :: ('MESH:D006851', 'Chemical') :: ['hydrochloric acid'] @entity11485 :: ('MESH:D005688', 'Chemical') :: ['galactosamine'] @entity4823 :: ('MESH:D005944', 'Chemical') :: ['glucosamine'] @entity1324 :: ('MESH:D000096', 'Chemical') :: ['acetone'] @entity291 :: ('9913', 'Species') :: ['bovine']
@entity291 :: (9913,Species) :: ['bovine']
