BACKGROUND AND AIMS: In previous studies, we described a clinical picture typically observed in frail old @entity1 , called "Psychomotor Disadaptation Syndrome" ( @entity1155 ), but we have never studied etiopathogenic data. The aim of this study was to complete the clinical picture, record cardiovascular risk factors and provide cerebral CT scan findings in @entity1 with @entity1155 . METHODS: 73 @entity1 with @entity1155 were recruited in the Geriatric Medicine departments of the University Hospitals of Dijon (Burgundy, France) and Strasbourg (Alsace, France); this group included prospectively all hospitalized @entity1 showing postural and gait abnormalities according to the following criteria: trend towards backward falling and gait pattern alteration characterized by hesitancy in initiation, small steps, and increase in the double support durations. General characteristics, @entity65 were collected for each @entity1 . For the detection of white matter changes (WMC), we used a third-generation CT scanner (GE CT HSA) evaluating a section of 7 mm at each interval of 8 mm. RESULTS: Neurological examination showed that "reactional @entity4372 " was observed in more than 90% of the @entity1 , and that no @entity1 showed normal reactive postural responses. Prior history of @entity101 was noted in 49% of the @entity1 , while a current antihypertensive treatment was taken by 13% of the @entity1 . @entity551 was observed in 44% of @entity1 . Severe or moderate periventricular lucencies on CT scan were found in 67% of the @entity1 , and severe @entity67 in 50.5% of the @entity1 . CONCLUSIONS: We advance that @entity1155 might be associated with WMC, and that @entity551 might be an important etiologic factor of WMC in causing reduction of the cerebral blood flow in subcortical areas.

Cardiovascular characteristics and cerebral CT findings in elderly subjects with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'people'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1155 :: ('MESH:D011596', 'Disease') :: ['PDS'] @entity4372 :: ('MESH:D009122', 'Disease') :: ['hypertonia'] @entity67 :: ('MESH:D018754', 'Disease') :: ['ventricular enlargement'] @entity551 :: ('MESH:D007022', 'Disease') :: ['Orthostatic hypotension', 'hypotension'] @entity65 :: ('MESH:D002318', 'Disease') :: ['neurological and cardiovascular information']
@entity1155 :: (MESH:D011596,Disease) :: ['psychomotor disadaptation syndrome']
