OBJECTIVE: One of the basic characteristics of @entity189 is its tendency to synchronous or metachronous multifocality. Thus the need to explore the entire urinary tract of @entity1 with urothelial neoformations. The aim of this article is to study the @entity5 of the upper urinary tract that appear synchronously with infiltrating @entity150 . The clinicopathological characteristics and the morbidity and mortality of en bloc surgery of both @entity5 are analyzed. METHODS: A retrospective study was carried out on 170 radical cystectomies for infiltrating @entity150 performed in our department over a 13-year period. @entity1 history, clinicopathological characteristics, complementary tests, type of surgery performed, postoperative complications and follow-up were analyzed. RESULTS: Tumor of the upper urinary tract appeared in 14 (1 bilateral) of these @entity1 and were synchronous in 10 cases. All @entity1 were male; mean age 63 years. Three were localized in the pelvis, 2 in the proximal ureter and 6 in the distal third. Diagnosis was made by IVP in 6 @entity1 and by US and antegrade pyelography in the other 4 @entity1 . Nephroureterectomy and radical cystectomy were performed en bloc in 8 cases; 6 had a Bricker procedure and 2 ileal substitution. Salvage radical cystectomy + distal ureterectomy were performed in the other two @entity1 . Two @entity1 submitted to en bloc surgery had postoperative complications; one presented prolonged ileua and the other required surgery for retroperitoneal @entity548 . The two @entity1 submitted to palliative surgery died of and @entity295 during the postoperative period. At 33 months' mean follow-up, 3 @entity1 have shown @entity5 progression. CONCLUSIONS: There is a high proportion of @entity5 of the upper urinary tract in our series of @entity1 with infiltrating @entity150 undergoing radical cystectomy, therefore we consider it necessary to explore the entire urinary system. Surgical @entity5 en bloc does not increase the morbidity and mortality.

[Synchronous XXXX of the upper urinary tract with @entity150 . Opportunity for nephroureterectomy and block-cystectomy].

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'removal of both tumors', 'synchronous tumor', 'tumors'] @entity189 :: ('MESH:D002277', 'Disease') :: ['urothelial carcinoma'] @entity150 :: ('MESH:D001749', 'Disease') :: ['bladder tumor', 'carcinoma of the bladder']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
