BACKGROUND: Although airway management with @entity4094 ( @entity4094 ) alone is discouraged in the @entity341 ( @entity341 ), our previous study demonstrated that many @entity1 were intubated using NMBs alone without sedatives. To refute this practice, we sought to compare the intubation success and adverse event rates between NMBs only and @entity1170 ( @entity1170 ). METHODS: This is a secondary analysis of the data from a prospective observational study of @entity341 @entity1 in 13 hospitals who underwent emergency airway management from April 2010 to August 2012. The primary outcome was intubation success rate on first attempt. The secondary outcomes were the intubation success rate in  <= 2 attempts and the intubation-related adverse event rate. We compared these outcomes between intubation attempts using @entity4094 alone and @entity1170 . We fit multivariable logistic regression models adjusting for potential confounders (age, sex, weight, primary indication for intubation, and training level of intubators). RESULTS: Overall, 852 @entity1 were eligible for this analysis, with 114 (13%) intubated with @entity4094 alone and 738 (87%) with @entity1170 . Between the @entity4094 -alone and @entity1170 groups, no significant differences were observed in the success rate on the first attempt (70 vs. 73%; P  =  0.48) or in  <= 2 attempts (89 vs. 91%; P  =  0.46), or in the adverse event rate (11 vs. 12%; P  =  0.58). Similarly, after adjusting for confounders, no significant differences were observed in any of these outcomes (all P  >  0.05). CONCLUSIONS: In this analysis of data from a large multicenter study of @entity341 @entity1 , we found no superior effectiveness of intubation with @entity4094 alone when compared to @entity1170 . Our data lend significant support to the concept that intubation with @entity4094 alone should be avoided in the @entity341 .

A comparison of emergency airway management between neuromuscular blockades alone and XXXX : an analysis of multicenter prospective study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4094 :: ('MESH:D009468', 'Disease') :: ['NMB', 'neuromuscular blockade'] @entity341 :: ('MESH:D004630', 'Disease') :: ['emergency department', 'ED'] @entity1170 :: ('MESH:C564983', 'Disease') :: ['RSI', 'rapid sequence intubation']
@entity1170 :: (MESH:C564983,Disease) :: ['rapid sequence intubation']
