Although the number of @entity1 with @entity459 ( @entity459 ) has increased since biochemical screening came to be widely employed, few data are available concerning the clinical analysis of Japanese @entity1 . We therefore tried to determine the recent clinical and biochemical state of Japanese @entity1 with @entity459 . Clinical and biochemical data were analyzed in a series of 103 @entity459 @entity1 who had been hospitalized in Kobe University Hospital during a 17 year period from 1979 to 1995. The data were obtained from the hospital records and additionally from information through questionnaires performed in 1995. @entity1 were 29 males and 74 females. The average ages at diagnosis were 53.4 +/- 16.0 (SD) year-old and 53.9 +/- 15.2 year-old, respectively. The major clinical symptoms were @entity1790 (35.9%), thirst/ @entity2011 (33.0%), easy fatigability (20.4%) and back @entity158 /lumbago (16.5%), but 19.4% of the @entity1 were asymptomatic. Out of 87 cases who received parathyroidectomy, 10 (11.5%) were diagnosed with @entity3243 . Age- and sex-corrected bone mineral density (BMD) of the radius was significantly lower in the group with back @entity158 /lumbago than in the group without the symptom. Similarly, radial BMD was lower in the group with a high serum alkaline phosphatase value. @entity1 with @entity1790 had a lower urinary @entity460 / @entity1011 ratio (UCa/ UCr; 0.305 +/- 0.188 mg/mg) than the @entity1 without @entity1790 (0.400 +/- 0.160 mg/mg). This inconsistent result suggests that some important factors except urinary @entity460 would contribute to urinary stone formation in @entity459 . Our data mostly agreed with previous reports on a Caucasian population except for a relatively high prevalence of @entity3243 , but the negative correlation between @entity1790 and urinary @entity460 was not easily explicable. This finding should be confirmed by analyzing a larger number of cases.

Clinical and biochemical presentation of XXXX in Kansai district of Japan.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity459 :: ('MESH:D049950', 'Disease') :: ['pHPT', 'primary hyperparathyroidism'] @entity2011 :: ('MESH:D011141', 'Disease') :: ['polyuria'] @entity1790 :: ('MESH:D053040', 'Disease') :: ['nephrolithiasis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity3243 :: ('MESH:D010282', 'Disease') :: ['parathyroid carcinoma']
@entity459 :: (MESH:D049950,Disease) :: ['primary hyperparathyroidism']
