OBJECTIVE: Our aims were to evaluate the correlation between @entity625 Activity Score 27-joint reduced count (JADAS27) with erythrocyte sedimentation rate (ESR) and JADAS27 with @entity1851 (CRP) scores and to test the agreement of both scores on classifying each disease activity state. We also aimed at verifying the correlation of the 2 scores across @entity4932 ( @entity4932 ) categories and to check the correlation between JADAS27-ESR and clinical JADAS27 (JADAS27 without ESR). METHODS: A nationwide cohort of @entity1 with @entity4932 registered in the Portuguese Register, Reuma.pt, was studied. JADAS27-CRP was adapted by replacing ESR with CRP level as the inflammatory marker. JADAS27-CRP was calculated similarly to JADAS27-ESR as the simple linear sum of its 4 components. Pearson's correlations and K statistics were used in the analyses. RESULTS: A total of 358 @entity1 had full data to calculate JADAS27; 65.4% were female and the mean    SD disease duration was 11.8    9.1 years. The correlation coefficient between JADAS27-ESR and JADAS27-CRP was 0.967 (P < 0.0001), although the correlation coefficient between ESR and CRP level was 0.335 (P < 0.0001). The strong correlation between JADAS27-ESR and JADAS27-CRP was maintained when compared within each @entity4932 category. The agreement between JADAS27-ESR and JADAS27-CRP across the 4 activity states was very good, showing 91.1% of the observations in agreement; K = 0.867 (95% confidence interval 0.824-0.91). The correlation between JADAS27 with ESR and JADAS27 without ESR was high (r = 0.97, P < 0.0001). CONCLUSION: JADAS27 based on CRP level correlated closely with JADAS27-ESR across all disease activity states and @entity4932 categories, indicating that both measures can be used in clinical practice. Moreover, the correlation of JADAS27 with and without ESR was also high, suggesting that this tool might be useful even in the absence of laboratorial measures.

Using the @entity625 activity score based on erythrocyte sedimentation rate or XXXX level: results from the portuguese register.

@entity4932 :: ('MESH:D001171', 'Disease') :: ['JIA', 'juvenile idiopathic arthritis'] @entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity625 :: ('MESH:D001168', 'Disease') :: ['Juvenile Arthritis Disease'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein']
@entity1851 :: (1401,Gene) :: ['C-reactive protein']
