A 38-year-old @entity1 underwent right hepatectomy for a huge @entity157 ( @entity157 )in the right hepatic lobe. Four months later, recurrent and metastatic disease were observed in the remnant liver and right lung, respectively. We performed a hepatectomy for the recurrent lesion because transcatheter arterial chemoembolization( @entity3375 )was not effective. After surgery, we initiated @entity2857 treatment for the lung @entity3 . One year later, the lung @entity3 worsened and @entity3 were observed in the mediastinal lymph nodes, and both metastatic lesions were resected. Seven months later, para-aortic lymph nodal @entity3 was observed and dissected. Three months later, @entity3 to the supraclavicular lymph node was observed. We performed particle radiation therapy and a complete response was achieved. One year later, @entity3 in both lungs were observed and resected. Despite continued @entity2857 administration throughout the clinical course, a @entity3 to the left adrenal gland was observed. This lesion was extirpated because no other recurrent lesions were detected. At 4 years and 6 months after the first operation, no other recurrences have occurred. Currently, @entity2857 is the initial drug of choice for @entity157 with extrahepatic @entity3 . It is possible to improve the prognosis of @entity1 with @entity157 and extrahepatic @entity3 by applying surgical treatment during the course of @entity2857 administration.

[Successful Multimodal Treatment for Aggressive Extrahepatic Metastatic XXXX - A Case Report].

@entity1 :: ('9606', 'Species') :: ['patients', 'man'] @entity3375 :: ('6868', 'Gene') :: ['TACE'] @entity2857 :: ('MESH:C471405', 'Chemical') :: ['sorafenib'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma']
@entity157 :: (MESH:D006528,Disease) :: ['Hepatocellular Carcinoma']
