BACKGROUND: Assessment of @entity295 severity is challenging. Available scoring systems require laboratory data. Therefore, a rapid tool would be useful. OBJECTIVE: To determine the role of mitral valve tissue Doppler imaging (TDI) as a prognostic tool in septic @entity1 . METHODS: For this prospective cohort, newly admitted septic @entity1 received TDI measurements of s wave (s), e' wave (e'), and E/e' ratio (E/e') within 5  min of resuscitation. Results were compared with @entity295 severity measured by @entity295 ( @entity295 ), @entity25079 , and Sequential Organ Failure Assessment (SOFA). RESULTS: Over 3  months, 63 @entity1 were enrolled. TDI parameters correlated with @entity295 , @entity25079 , and SOFA (r  =  -0.53, r  =  -0.55, r  =  -0.36, respectively, for s, p  <  0.005; r  =  -0.56, r  =  -0.49, r  =  -0.40, respectively, for e', p  <  0.005; and r  =  0.56; r  =  0.48; r  =  0.46, respectively, for E/e', p  <  0.005). Mean s and e' decreased among @entity295 , severe @entity295 , and @entity326 @entity1 (14.2; 12.05; 10.14  cm/s, respectively, for s, p  =  0.0048 and 18.28; 15.14; 12.12  cm/s, respectively, for e', p  =  0.003), whereas mean E/e' increased among @entity295 stages (4.76; 6.51; and 8.14, respectively, p  =  0.001). Mean s and e' were higher in survivors (13.25 vs. 7.33  cm/s, for s, p  <  0.0001; and 16.4 vs. 9  cm/s for e', p  =  0.0025); mean E/e' was higher in nonsurvivors (10.85 vs. 5.63, p  <  0.0001). On univariate analysis, odds ratios (ORs) for death related to s, e', and E/e' were, respectively, 0.517 (95% confidence interval [CI] 0.344-0.775), 0.60 (95% CI 0.433-0.833), and 1.953 (95% CI 1.256-3.008); p  <  0.05 for all. Multiple logistic analysis showed an OR of 1.737 (95% CI 1.037-2.907, p  =  0.035) for death related to E/e'. CONCLUSION: TDI may be useful to assess disease severity and prognosis in newly diagnosed septic @entity1 .

Left Ventricle Tissue Doppler Imaging Predicts Disease Severity in  Septic XXXX Newly Admitted in an Emergency Unit.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity25079 :: ('55291', 'Gene') :: ['Simplified Acute Physiology Score (SAPS) 3', 'SAPS 3'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis', 'Mortality in Emergency Department Sepsis', 'MEDS'] @entity326 :: ('MESH:D012772', 'Disease') :: ['septic shock']
@entity1 :: (9606,Species) :: ['Patients']
