22 @entity1 , hospitalized for observation and treatment of @entity697 , participated in a study designed to examine the extent of infective involvement of the testicular parenchyma in conjunction with acute nonspecific @entity32 . An attempt was made in a followup to classify possible injury to spermatogenesis occurring after @entity3892 . Age at onset of @entity697 varied between 21-82 years. The @entity3892 was unilateral in 20 @entity1 and bilateral in 2 @entity1 . 12 @entity1 had symptoms of posterior @entity6369 . 18 @entity1 were followed for 2-3 years after the acute onset. 3 of the older @entity1 had died of intercurrent diseases at the time of the followup. Aspiration biopsy from the testis was performed with a 23-gauge needle; punctures were carried out during short-term @entity7908 4-15 days (average 7 days) after the onset of the @entity3892 . A section biopsy of testicular parenchyma was taken for histopathologic examination in 4 @entity1 . Bacteriologic cultivation of the urine was performed in all 22 @entity1 , and a portion of the aspirated material at testis puncture was sent for bacteriologic examination in 11 @entity1 . The followup examination included palpation of the testes, at which time turgidity and consistency on both sides were judged. Atrophy of the testis is defined as a difference in consistency, as well as in size, between the affected and the healthy sides. @entity194 was considered to be present if the combined axis measurements for the 2 sides differed by 10 mm or more and if the consistency of the testes differed. 16 of the @entity1 showed an inflammatory cell reaction in the testis; a reduction of spermatogenesis was observed in the same number of cases. There was a significant correlation between the degree of the inflammatory cell reactions and the reduction of spermatogenesis. The 9 @entity1 who showed a pronounced inflammatory cell reaction all had marked reduction of spermatogenesis. Of the 18 followup @entity1 , 12 showed @entity194 . Both of the bilateral caseds were among these. 6 @entity1 were judged to have clinically normal testes. There was significant correlation between the presence of @entity194 2-3 years after the episode of @entity697 and the degree of inflammatory cell reaction during the acute infection phase. Of the 8 @entity1 who showed pronounced inflammatory cell reactions, @entity194 of the testis was found later in 7; 4 of the @entity1 who did not show any inflammatory cell reactions had normal testis size and turgidity.

Changes in the testis parenchyma caused by XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation in the epididymis'] @entity6369 :: ('MESH:D014526', 'Disease') :: ['urethritis'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute nonspecific epididymitis', 'acute epididymitis'] @entity3892 :: ('MESH:D004823', 'Disease') :: ['nonspecific epididymitis', 'epididymitis'] @entity7908 :: ('MESH:D053608', 'Disease') :: ['narcosis'] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy', 'Testicular atrophy']
@entity697 :: (MESH:D000208,Disease) :: ['acute nonspecific epididymitis']
