OBJECTIVE: The purpose of this study was to analyze clinical data and magnetic resonance imaging (MRI) findings for @entity1 with asymptomatic, incidentally identified @entity1644 associated with @entity1645 who were monitored for more than 10 years, and to clarify the natural history of these lesions. METHODS: The clinical records of nine @entity1 who had not been surgically treated and were regularly subjected to neurological and MRI examinations were analyzed. In MRI studies, the axial diameter of the syrinx at the widest level, the longitudinal extent of the syrinx, and the extent of tonsillar herniation into the spinal canal were analyzed. As a control, MRI findings for 11 @entity1 with symptomatic @entity1644 associated with @entity1645 who had been surgically treated were also analyzed, and these MRI parameters were statistically compared between the asymptomatic and symptomatic groups. RESULTS: One @entity1 underwent surgery, because of neurological changes, 7 years after the first visit. None of the remaining @entity1 demonstrated any neurological change during the follow-up period (11.2+/-0.7 yr), and all of them have been faring well without surgery. No statistically significant differences in MRI findings between the asymptomatic and symptomatic groups were observed. CONCLUSION: The long-term clinical courses of @entity1 with asymptomatic, incidentally identified @entity1644 associated with @entity1645 were observed to be benign. MRI parameters did not provide predictable values to recommend interventional surgery. Unless changes in neurological or MRI findings are detected, early interventional surgery is not necessary.

Incidentally identified XXXX associated with @entity1645 : is early interventional surgery necessary?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1645 :: ('MESH:D001139', 'Disease') :: ['Chiari I malformations'] @entity1644 :: ('MESH:D013595', 'Disease') :: ['syringomyelia']
@entity1644 :: (MESH:D013595,Disease) :: ['syringomyelia']
