OBJECTIVES: Comparison of magnetic resonance elastography (MRE) and diffusion-weighted imaging (DWI) for differentiating @entity409 (FLLs). METHODS: Seventy-nine subjects with 124 FLLs (44 benign and 80 malignant) underwent both MRE and DWI. MRE was performed with a modified gradient-echo sequence and DWI with a free breathing technique (b   =   0.500). Apparent diffusion coefficient (ADC) maps and @entity2693 maps were generated. FLL mean @entity2693 and ADC values were obtained by placing regions of interest over the FLLs on @entity2693 and ADC maps. The accuracy of MRE and DWI for differentiation of benign and malignant FLL was compared using receiver operating curve (ROC) analysis. RESULTS: There was a significant negative correlation between @entity2693 and ADC (r   =   -0.54, p   <   0.0001) of FLLs. Malignant FLLs had significantly higher mean @entity2693 (7.9kPa vs. 3.1kPa, p   <   0.001) and lower mean ADC (129 vs. 200   *   10(-3)mm(2)/s, p   <   0.001) than benign FLLs. The sensitivity/specificity/positive predictive value/negative predictive value for differentiating malignant from benign FLLs with MRE (cut-off, >4.54kPa) and DWI (cut-off, <151   *   10(-3)mm(2)/s) were 96.3/95.5/97.5/93.3  % (p   <   0.001) and 85/81.8/88.3/75  % (p   <   0.001), respectively. ROC analysis showed significantly higher accuracy for MRE than DWI (0.986 vs. 0.82, p   =   0.0016). CONCLUSION: MRE is significantly more accurate than DWI for differentiating benign and malignant FLLs. KEY POINTS:     MRE is superior to DWI for differentiating benign and malignant focal @entity409 .     @entity75 with large fibrous components may have higher @entity2693 with MRE.     @entity201 tend to have @entity157 .     @entity8055 tend to have lower @entity2693 than @entity4383 .     MRE is superior to conventional MRI in differentiating @entity409 .

Comparison of magnetic resonance elastography and diffusion-weighted imaging for differentiating XXXX .

@entity8055 :: ('MESH:D018248', 'Disease') :: ['Hepatocellular adenomas'] @entity75 :: ('MESH:D001927', 'Disease') :: ['Benign lesions'] @entity409 :: ('MESH:D008107', 'Disease') :: ['malignant and benign focal liver lesions', 'liver lesions', 'benign and malignant liver lesions'] @entity201 :: ('MESH:D018281', 'Disease') :: ['Cholangiocarcinomas'] @entity4383 :: ('MESH:D020518', 'Disease') :: ['focal nodular hyperplasia'] @entity157 :: ('MESH:D006528', 'Disease') :: ['higher stiffness than hepatocellular carcinomas'] @entity2693 :: ('MESH:C566112', 'Disease') :: ['stiffness']
@entity409 :: (MESH:D008107,Disease) :: ['benign and malignant liver lesions']
