BACKGROUND: Stent @entity715 is an infrequent complication of intracoronary stenting that often has devastating clinical consequences. This study assesses the additional benefit of heparin coating with the BX VELOCITY Balloon-Expandable Stent with HEPACOAT, Carmeda end-point attached heparin (HEPACOAT) in @entity1 with de novo or restenotic native @entity453 treated with @entity117 monotherapy after optimal stenting. METHODS AND RESULTS: This was a multicenter, prospective, nonrandomized, pilot study. Two hundred @entity1 (69% @entity1 ; mean age, 64.1+/-11.2 years) meeting the eligibility criteria were treated with the HEPACOAT stent and @entity117 alone after stenting. Any other antiplatelet or anticoagulation therapy was not permitted. Procedural success was achieved in all @entity1 . There were 3 postprocedural non-Q-wave @entity583 . The primary end point of stent @entity715 at 30 days occurred in 2 of 200 @entity1 (1%): in one after blunt @entity764 and in the other in the setting of essential @entity1148 . Major adverse @entity299 ( @entity204 , @entity583 , @entity75 revascularization, and coronary artery bypass grafting) were observed at 30 days in 5 of 200 (2.5%) @entity1 . CONCLUSIONS: The BX VELOCITY stent with HEPACOAT and @entity117 alone after the procedure was safe in select @entity1 with de novo or restenotic lesions in native coronary arteries. Heparin coating provides additional protection against stent @entity715 .

Safety of an XXXX -alone regimen after intracoronary stenting with a heparin-coated stent: final results of the HOPE (HEPACOAT and an Antithrombotic Regimen of @entity117 Alone) study.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity1148 :: ('MESH:D013922', 'Disease') :: ['thrombocytosis'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'myocardial infarctions'] @entity75 :: ('MESH:D001927', 'Disease') :: ['target lesion'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity764 :: ('MESH:D013898', 'Disease') :: ['chest trauma'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery lesions'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity117 :: (MESH:D001241,Chemical) :: ['aspirin']
