OBJECTIVE: To investigate the roles of @entity4567 ( @entity4568 )-added total parenteral nutrition ( @entity8856 ) in septic animals and stressed @entity1 . METHODS: Thirteen adult @entity235 were randomly assigned to one of two study groups 6 hours after the induction of severe @entity1320 . Group @entity8856 (n = 6) received 70 kcal.kg-1.d-1 of nonprotein calorie (NPC) and 0.56 g.kg-1.d-1 of @entity1568 . 1 g/kg of @entity4568 was also infused to the animals in group @entity8856 + @entity4568 (n = 7) everyday. In the clinical study, the control group received routine @entity8856 , while the study group (n = 16) was treated with @entity8856 plus @entity4568 (5 g, two times a day) for 7 days. RESULTS: In @entity235 with @entity8856 support, plasma @entity855 levels were not changed significantly, while the value in the @entity8856 + @entity4568 group increased significantly from 0.18 mumol/L to 0.46 mumol/L at 24 h and 0.51 mumol/L at 48 h (P < 0.01). Muscular @entity855 increased markedly in the @entity8856 + @entity4568 group. Muscular @entity1734 values were not significantly changed in the @entity8856 group, but the values increased in the @entity8856 + @entity4568 group from 4.06 mumol/g.wt at the beginning to 4.93 mumol/g.wt at 24 h and 5.60 mumol/g.wt at 48 h (P < 0.05), with a cytochrome oxidase increase in immunohistochemistry stain. In the clinical study, plasma @entity855 levels increased and urinary @entity7981 production significantly decreased with an improved value for positive accumulative @entity1568 balance in the @entity4568 -infused group. CONCLUSION: Our results suggest that total parenteral nutrition support with the supplement of @entity4567 has a positive role in body energy production and protein metabolism in septic animals and stressed @entity1 .

@entity4567 -added total parenteral nutrition in septic animals and stressed XXXX .

@entity4568 :: ('MESH:C020332', 'Chemical') :: ['FDP'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity1734 :: ('CHEBI:17287', 'Chemical') :: ['creatine phosphate'] @entity1568 :: ('MESH:D009584', 'Chemical') :: ['nitrogen'] @entity235 :: ('9615', 'Species') :: ['dogs'] @entity855 :: ('MESH:D000255', 'Chemical') :: ['ATP'] @entity4567 :: ('MESH:C029063', 'Chemical') :: ['fructose-1,6-diphosphate'] @entity7981 :: ('CHEBI:70959', 'Chemical') :: ['3-methylhistidine'] @entity1320 :: ('MESH:D059413', 'Disease') :: ['intra-abdominal infection'] @entity8856 :: ('CHEBI:44409', 'Chemical') :: ['TPN']
@entity1 :: (9606,Species) :: ['patients']
