We have performed a randomized, double-blind comparison of two epidural drug regimens for @entity1337 in labour. In the @entity1341 group (BUPIV), 101 healthy parturients received 0.1% @entity1341 with @entity3575 2 microg ml(-1). In the @entity1342 group (ROPIV), 102 @entity1 received 0.2% @entity1342 . Both groups received an initial loading dose of 15 ml, a continuous infusion of 8 ml h(-1), and top-ups of 10 ml. @entity158 not responding to a routine top-up was treated with an 'escape' top-up of 10 ml 0.25% @entity1341 . The two groups were compared for complete @entity1337 at 30 min, routine and 'escape' top-up requirements, midwife assessment of analgesic efficacy, delivery mode, @entity1 visual analogue scores (VAS) for first and second stage @entity1337 , overall satisfaction, and @entity1 assessment of motor blockade. @entity1 receiving @entity1342 received fewer routine top-ups (median 1.0 vs. 2.0, P=0.001) and fewer escape top-ups (9.8% vs. 21.8%, P=0.02). The @entity1342 group was more likely to be @entity158 free in the first stage (51% vs. 33.7%, P=0.01). There were no significant differences in @entity1 ' assessment of motor block or mode of delivery between the groups. @entity158 relief and satisfaction scores from midwives and @entity1 were consistently better in the @entity1342 group, but did not reach statistical significance.

@entity1342 0.2% versus @entity1341 0.1% with XXXX : a double blind comparison for @entity1337 during labour.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'patient'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity1342 :: ('MESH:C037663', 'Chemical') :: ['ropivacaine'] @entity1341 :: ('MESH:D002045', 'Chemical') :: ['bupivacaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Breakthrough pain', 'Pain', 'pain'] @entity3575 :: ('MESH:D005283', 'Chemical') :: ['fentanyl']
@entity3575 :: (MESH:D005283,Chemical) :: ['fentanyl']
