INTRODUCTION AND OBJECTIVES: The concentration of certain proinflammatory cytokines has been found to be elevated in @entity1 with @entity1187 . Many studies have shown that coronary ischemic accidents do not show a uniform distribution throughout the day, but instead exhibit rhythmic variations. The objective of this study is to determine whether there is a circadian pattern of variation in the concentrations of proinflammatory cytokines in @entity1 with @entity583 . @entity1 AND METHOD: The sample included 40 @entity1 with @entity583 and 40 controls. Levels of @entity38453 were determined in the first 24 hours after the acute coronary ischemic episode. Blood samples were extracted at 3:00 a.m. (period of darkness) and at 10:00 a.m. (period of daylight). RESULTS: Both groups were similar in age, sex distribution, and coronary risk factors. @entity650 levels showed a significant variation between daylight and nighttime concentrations in @entity1 with @entity583 and controls (41.93 5.90/100.39 13.60 vs 25.76 4.45/52.67 7.73 pg/ml). However, @entity650 concentrations were higher in the @entity583 group than in the control group. @entity1356 concentrations did not vary between daylight and darkness. CONCLUSIONS: In both the control group and @entity583 group, @entity650 concentrations varied between daylight and darkness. @entity1 with @entity583 shown a higher concentration of @entity650 secondary to the physiological response to tissue damage. Circadian variations can affect the measurements obtained for different physiological and biochemical parameters.

[Circadian variations in proinflammatory cytokine concentrations in XXXX ].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndrome'] @entity650 :: ('3569', 'Gene') :: ['Interleukin 6', 'interleukin 6'] @entity1356 :: ('3553', 'Gene') :: ['Interleukin 1 beta'] @entity38453 :: ('3569;3553', 'Gene') :: ['interleukin 6 and 1 beta'] @entity583 :: ('MESH:D009203', 'Disease') :: ['acute myocardial infarction']
@entity583 :: (MESH:D009203,Disease) :: ['acute myocardial infarction']
