BACKGROUND: Surgery remains the mainstay of treatment for @entity9075 , and radiation and chemotherapy also have been applied widely as adjuvant and palliative procedures. METHODS: We compiled records of 1,320 @entity1 with @entity9075 who were treated from 1990 to 1994 in 115 institutes certified as special institutes for general thoracic surgery by The Japanese Association for Chest Surgery. RESULTS: @entity1 with stage I @entity704 were treated with only surgery, and @entity1 with @entity34 and @entity6732 underwent surgery and additional radiotherapy. @entity1 with stage IV @entity704 were treated with radiation or chemotherapy. The Masaoka clinical stage is an excellent predictor of the prognosis of @entity704 , but not @entity6732 . In stage III and IV @entity704 , the 5-year survival rates of total resection, subtotal resection, and inoperable groups were 93%, 64%, and 36%, respectively. On the other hand, in @entity704 , the 5-year survival rates of total resection, subtotal resection, and inoperable groups were 67%, 30%, and 24%, respectively. Prophylactic mediastinal radiotherapy could not prevent local recurrences effectively in @entity1 with totally resected @entity34 . Adjuvant therapy including radiation or chemotherapy did not improve the prognosis in @entity1 with totally resected III and VI @entity704 . CONCLUSIONS: Total resection is the most important factor in the treatment of @entity9075 . There is value in debulking surgery in invasive @entity704 , but not in @entity704 . We doubt that adjuvant therapy is valuable for @entity1 with totally resected invasive @entity704 .

Therapy for XXXX : a clinical study of 1,320 @entity1 from Japan.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity704 :: ('MESH:D013945', 'Disease') :: ['thymic carcinoma', 'thymoma', 'thymoma and thymic carcinoma'] @entity6732 :: ('MESH:D013953', 'Disease') :: ['thymic carcinoid'] @entity9075 :: ('MESH:C536905', 'Disease') :: ['thymic epithelial tumors'] @entity34 :: ('MESH:D016609', 'Disease') :: ['stage II and III thymoma']
@entity9075 :: (MESH:C536905,Disease) :: ['thymic epithelial tumors']
