BACKGROUND: Prior abdominal surgery increases complexity of abdominal operations. Effort to prevent injury during adhesiolysis might result in less extensive bowel resection in @entity14 surgery. The aim of this study was to evaluate the effect of prior abdominal surgery on the outcome of @entity14 surgery. METHODS: A nationwide prospective database of @entity1 with primary @entity14 resection in The Netherlands between 2010 and 2012 was reviewed for histopathology, morbidity and mortality in @entity1 with compared to @entity1 without prior abdominal surgery. RESULTS: 9042 @entity1 with and 17,679 without prior abdominal surgery were analyzed. After prior abdominal surgery 20.7  % had less than 10 lymph nodes in the histopathological specimen compared to 17.8  % without prior abdominal surgery (adjusted @entity36386 , 95  % CI 1.09-1.26). Adjusted ORs for less than 10 and 12 lymph nodes were significant in @entity694 resection and not in @entity5 resection. Subgroups of @entity1 who had previous hepatobiliary surgery or other abdominal surgery had a higher incidence of inadequate number of harvested lymph nodes. Prior colorectal surgery increased the percentage of positive circumferential rectal resection margin by 64  % (12.5 and 7.6  %; adjusted OR 1.70, 95  % CI 1.21-2.39). For @entity694 morbidity was significantly higher in @entity1 with prior surgery (33.2 and 29.7  %; adjusted @entity65481 , 95  % CI 1.10-1.26), 30-day mortality was comparable (4.7  % prior surgery and 3.8  % without prior surgery; adjusted OR 1.01, 95  % CI 0.88-1.17). CONCLUSIONS: Prior abdominal surgery compromises the quality of resection and increases postoperative morbidity in @entity1 with primary @entity14 .

Prior Abdominal Surgery Jeopardizes Quality of Resection in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity36386 :: ('81448', 'Gene') :: ['OR 1.17'] @entity5 :: ('MESH:D009369', 'Disease') :: ['rectal cancer'] @entity65481 :: ('391114', 'Gene') :: ['OR 1.18'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer']
@entity14 :: (MESH:D015179,Disease) :: ['Colorectal Cancer']
