OBJECTIVE: The objective of this review is to explore how current research measures the effectiveness of @entity4185 ( @entity4185 ) in smokers with @entity565 . DATA SOURCES: PubMed, CINAHL and PsycINFO databases were searched for combinations of terms relating to @entity565 , @entity286 use and @entity4185 effectiveness. STUDY SELECTIONS: The search was limited to articles published between 2004 and 2015, in English language. Studies met inclusion criteria if reporting the use of guideline-based @entity565 control indicators to measure the therapeutic effects of @entity4185 or @entity4185 combination therapies. This review did not exclude articles based on study design. Data were extracted and summarized to describe how indicators were measured across studies in order to characterize and describe the effects of @entity4185 in smokers. RESULTS: Thirteen studies were included in this review. Six of these 13 studies used only one indicator to measure @entity565 control in smokers and @entity4185 was found to improve @entity565 in only one of six of these studies. Of studies evaluating combination therapy, three of four studies reported a therapeutic benefit to smokers. In these studies of combination therapy multiple indicators of control were measured to assess drug effects. CONCLUSIONS: To assess the therapeutic benefit of @entity4185 drugs in smokers, multiple indicators should be measured to determine if current therapy is improving @entity565 control. Asthma therapy should then be adjusted based on the @entity1 's current @entity565 status. The development of clinical treatment guidelines for @entity748 smokers may help clinicians make best-practice, evidence-based recommendations in order to optimize care for these @entity1 .

Use of XXXX control indicators in measuring inhaled corticosteroid effectiveness in @entity748 smokers: a systematic review.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity748 :: ('MESH:D013224', 'Disease') :: ['asthmatic'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity4185 :: ('MESH:D058545', 'Disease') :: ['inhaled corticosteroids', 'ICS']
@entity565 :: (MESH:D001249,Disease) :: ['asthma']
