Objective. @entity6511 ( @entity6511 ), a marker of @entity32 , is associated with @entity65 . This prospective study of an inception cohort aimed to investigate whether the level of @entity6511 is associated with subclinical @entity731 in @entity1 with @entity309 ( @entity309 ). Methods. @entity1 from northern Sweden diagnosed with early @entity309 were consecutively recruited into an ongoing prospective study. From these, all @entity1  <=60 years (n = 71) were included for measurements of subclinical @entity731 at inclusion (T0) and five years later (T5). Forty age- and sex-matched controls were included. The @entity1 were clinically assessed, SCORE, Reynolds Risk Score, and Larsen score were calculated, and blood samples were drawn from all individuals at T0 and T5. Results. There was no significant difference in the level of @entity6511 between @entity1 with @entity309 and controls (p > 0.05). In simple linear regression models among @entity1 with @entity309 , @entity6511 at T0 was significantly associated with @entity121 ( @entity121 ) at T0 and T5, @entity384 ( @entity384 ) at T0 and T5, ever smoking, male sex, HDL- @entity165 (inversely), non-HDL- @entity165 , SCORE, Reynolds Risk Score, and Larsen score (p < 0.05). Conclusion. In this cohort of @entity1 with early @entity309 , the concentration of @entity6511 was associated with both subclinical @entity731 and disease severity.

Is @entity6511 a Link between Inflammation and Subclinical XXXX in @entity309 ?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['vascular inflammation'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA'] @entity384 :: ('MESH:D002311', 'Disease') :: ['flow mediated dilation', 'FMD'] @entity6511 :: ('7941', 'Gene') :: ['Lipoprotein-associated phospholipase A2', 'Lp-PLA2'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity121 :: ('MESH:D009135', 'Disease') :: ['intima media thickness', 'IMT'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerosis']
