BACKGROUND: Overweight and @entity28 decrease the effectiveness of antihypertensive therapy despite the more frequent use of polytherapy. One method for improving therapy effectiveness is by decreasing non-compliance with the use of @entity2300 ( @entity2300 ). The aim of this study was to assess the effectiveness, tolerance, and satisfaction with @entity3372 / @entity3591 @entity2300 antihypertensive therapy in relation to nutritional status. METHODS: The survey enrolled 24,240 @entity101 @entity1 recently switched to @entity3372 / @entity3591 @entity2300 (EGIRAMLON) at the same doses as previously prescribed separate pills. RESULTS: The effectiveness of antihypertensive therapy increased during follow-up from 32.9% to 76.5%. Overweight and @entity28 were associated with the increased risk of not attaining the recommended BP values [adjusted for age OR=0.74 (95% CI 0.67-0.83) and 0.70 (0.61-0.81) for overweight; 0.54 (0.47-0.60) and 0.49 (0.42-0.57) for @entity28 , at the first and the second examination, respectively]. "Very good" or "good" the FDP tolerance was reported by 98.8%, 97.6% and 96.4%, respectively. Adverse events (AE) were reported in 0.35% of @entity1 regardless of nutritional status. High levels of satisfaction with the @entity2300 were reported by 57.0% of @entity1 with normal weight, 54.5% of overweight, and 50.6% with @entity28 . Effectiveness and convenience were the most important for @entity1 . CONCLUSIONS: The effectiveness of therapy with @entity3372 / @entity3591 @entity2300 in the study population was high, but slightly lower in overweigh and @entity28 . This @entity2300 was well tolerated and a significant number of @entity1 satisfied with the therapy regardless of nutritional status. Although the perceived tolerance and satisfaction with treatment were lower in @entity28 and overweight than in normal weight @entity1 ; the incidence of AE and perceived benefit from the use of a single-pill, compared to multiple tablets, were comparable irrespective of nutritional status.

@entity3372 / @entity3591 single pill - Effectiveness, tolerance and XXXX satisfaction with antihypertensive therapy in relation to nutritional status.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3372 :: ('MESH:D017257', 'Chemical') :: ['ramipril'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese', 'obesity'] @entity3591 :: ('MESH:D017311', 'Chemical') :: ['amlodipine'] @entity2300 :: ('MESH:D011681', 'Disease') :: ['FDC', 'fixed-dose combinations']
@entity1 :: (9606,Species) :: ['patient']
