OBJECTIVES: This study reports the radiographic analysis of a split-mouth, single-blinded, randomised controlled clinical trial which was designed to compare the efficacy of simplified papilla preservation flap (SPPF) with or without guided tissue regeneration (GTR) in @entity1 with @entity146 ( @entity146 ). METHODS: Eighteen @entity146 @entity1 who had similar bilateral @entity154 were treated. In all @entity1 , the defects presented with radiographic evidence of an intrabony defect >= 3 and >= 5  mm of @entity6885 ( @entity6885 ). The surgical procedures included access for root instrumentation using SPPF alone (control) or, after debridement, a placement of resorbable GTR membrane (test). The standardised radiographic assessments were carried out at pre-surgical baseline and at 6 and 12  month post-surgery. Radiographic linear measurements and subtraction radiography were used as the method of analysis. RESULTS: Both treatments showed significant improvements in linear radiographic bone fill and defect resolution at 6 and 12  months, compared to baseline. The 12-month subtraction radiography at the GTR sites showed a significant improvement compared to the 6-month outcomes. CONCLUSIONS: Both therapies were effective in the treatment of @entity154 in @entity146 @entity1 although no significant differences between them could be demonstrated. The finding that the bone fill and resolution of the defect at the GTR sites were significantly higher at 12  months than at 6  months after treatment indicates that bone regeneration is still an ongoing process at 6  months post-surgery. CLINICAL RELEVANCE: Radiographic assessment of periodontal regeneration should be carried out at 12  months post-surgery in order to evaluate the complete healing of the @entity154 .

Radiographic outcomes following treatment of intrabony defect with guided tissue regeneration in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity154 :: ('MESH:D000013', 'Disease') :: ['bony defect', 'intrabony defects'] @entity6885 :: ('MESH:D010514', 'Disease') :: ['periodontal pocket depths', 'PPD'] @entity146 :: ('MESH:D001523', 'Disease') :: ['AgP', 'aggressive periodontitis']
@entity146 :: (MESH:D001523,Disease) :: ['aggressive periodontitis']
