Synaptological characteristics of synapses between axonal boutons of the trigeminal mesencephalic nucleus (Vme) neurons and the hypoglossal nucleus (XII) motoneurons (MNs) were studied using @entity7506 ( @entity7506 ) anterograde labeling combined with horseradish peroxidase (HRP) retrograde transport in the @entity35 . @entity7506 was initially iontophoresed into Vme unilaterally and 7 days later HRP was injected into the anterior two-thirds of the @entity5773 . After histochemical reactions, @entity7506 anterogradely labeled boutons were seen to appose closely to somata and dendrites of HRP retrogradely labeled MNs in XII by light microscopy. A total of 212 @entity7506 -labeled Vme boutons were examined ultrastructurally, which had an average diameter of 1.3 +/- 0.4 microm and contain small clear spherical vesicles. Eighty-eight percent of Vme boutons (187/212) synapsed on dendrites of HRP-labeled XII MNs. Twenty-five Vme boutons (25/212, 12%) made synapses with somata of HRP-labeled XII MNs. Thirty-five percent (74/212) of @entity7506 -labeled Vme boutons were also contacted by unlabeled P-type terminals. Presynaptic P-type terminals contained spherical (47%, 35/74), pleomorphic (43%, 32/74), and flattened (10%, 7/74) synaptic vesicles. Thus, P-type terminals (as a presynaptic element), @entity7506 -labeled Vme boutons, and XII MNs constitute axoaxodendritic and axoaxosomatic synaptic triads. There are four types of synaptic microcircuits in XII neuropil: synaptic convergence, synaptic divergence, presynaptic inhibition synaptic circuits, and feedforward regulation circuits. This detailed ultrastructure examination of the synaptic organization between Vme neurons and XII MNs provides insights into the synaptic mechanisms of the trigeminal proprioceptive afferents involved in the @entity89 during oral motor behaviors.

Synaptic organization of monosynaptic connections from mesencephalic trigeminal nucleus neurons to hypoglossal motoneurons in the XXXX .

@entity35 :: ('10116', 'Species') :: ['rat'] @entity5773 :: ('MESH:D014060', 'Disease') :: ['ipsilateral tongue'] @entity89 :: ('MESH:D007571', 'Disease') :: ['jaw-tongue reflex and coordination'] @entity7506 :: ('MESH:C076397', 'Chemical') :: ['BDA', 'biotinylated dextran amine']
@entity35 :: (10116,Species) :: ['rat']
