FOCUSED QUESTION: In @entity1 with @entity33 , what is the efficacy of professionally-administered plaque removal (PAPR) with adjunctive measures on changing signs of @entity32 compared with @entity12982 alone? MATERIAL _ METHODS: After electronic database and hand search, 19 full-text articles were independently screened by two reviewers. Finally, a total of 7 studies fulfilled the inclusion criteria. The @entity353 ( @entity353 ) in @entity548 on probing- (BOP) (primary outcome), gingival index- (GI) and probing pocket depth- ( @entity5951 ) reductions was estimated (random effect model). RESULTS: @entity353 in BOP reduction between test and control groups amounted to -8.16% [SD=4.61; p=0.07; 95% CI (-17.20, 0.88)] not favouring adjunctive antiseptic or antibiotic (local, systemic) therapy over PAPR alone. @entity353 in GI and @entity5951 reductions amounted to -0.12 [SD=0.13; p=0.34; 95% CI (-0.38, 0.13)] and -0.056 mm [SD=0.10; p=0.60; 95% CI (-0.27, 0.16)] not favouring adjunctive (antiseptics, systemic antibiotics, air abrasive device) over control measures, respectively. Most studies evaluated reported on residual BOP and GI scores after therapy. CONCLUSIONS: Adjunctive therapy may not improve the efficacy of PAPR in reducing BOP, GI, and @entity5951 scores at @entity33 sites. Despite clinically important improvements, a complete disease resolution may not be expected by any of the treatment protocols investigated. This article is protected by copyright. All rights reserved.

Efficacy of professionally-administered plaque removal with or without adjunctive measures for the treatment of XXXX . A systematic review and meta-analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity353 :: ('MESH:D015431', 'Disease') :: ['WMD', 'weighted mean difference'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity33 :: ('MESH:D052016', 'Disease') :: ['peri-implant mucositis', 'mucositis'] @entity12982 :: ('142', 'Gene') :: ['PARP'] @entity5951 :: ('MESH:D005888', 'Disease') :: ['PD']
@entity33 :: (MESH:D052016,Disease) :: ['peri-implant mucositis']
