BACKGROUND: Many disparities exist in treatment of early stage @entity0 . Our objective was to conduct a cross-sectional registry analysis of @entity1 with early stage @entity0 in @entity14755 Kentucky to identify factors affecting surgical choice [breast conserving surgery (BCS) vs mastectomy] and appropriate use of adjuvant @entity1161 ( @entity1161 ). METHODS: Database collection was done through the Kentucky @entity5 Registry. Inclusion criteria included female @entity0 @entity1 diagnosed between 1998 and 2007. @entity1 were diagnosed with @entity513 in situ or American Joint Committee on @entity5 stage I or II disease. Database search was limited to @entity14755 residents. Statistical analyses were carried out to identify variables affecting surgical choice, receipt of @entity1161 , and survival. RESULTS: Analysis evaluated 5,541 @entity14755 @entity1 . The distribution of surgery favored BCS (54.1%) over mastectomy (45.9%). On multivariate analysis, the most significant factors for mastectomy were advanced stage [odds ratio (OR) 2.571, P<0.0001], rural location (OR 2.075, P<0.0001), and insurance status (OR 1.546, P<0.0001). Of @entity1 choosing BCS, 56.2% received adjuvant @entity1161 . On multivariate analysis age >70 years (OR 2.506, P<0.0001), rural location (OR 2.416, P<0.0001), and lack of insurance (OR 1.651, P=0.0168) were the strongest predictors for not receiving adjuvant @entity1161 . CONCLUSIONS: Mastectomy rate remains higher and the rate of @entity1161 after BCS is lower in @entity14755 @entity1 compared with other contemporary studies of @entity1 with @entity513 in situ and early stage @entity0 .

Patterns of care with regard to surgical choice and application of adjuvant @entity1161 for preinvasive and early stage XXXX in rural Appalachia.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity1161 :: ('MESH:D011832', 'Disease') :: ['radiation therapy', 'RT'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cancer'] @entity14755 :: ('MESH:D028227', 'Disease') :: ['Appalachian'] @entity513 :: ('MESH:D044584', 'Disease') :: ['ductal carcinoma']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
