Although most therapeutic efforts and experimental @entity64 models focus on the concept of complete occlusion of the middle cerebral artery as a result of @entity887 from the carotid artery or cardiac chamber, relatively little is known about the @entity64 mechanism of intrinsic @entity2500 . Differences in @entity64 pathophysiology may require different strategies for prevention and treatment. We prospectively studied 30 consecutive acute @entity385 @entity1 with @entity2500 detected by transcranial Doppler and magnetic resonance angiography. @entity1 underwent microembolic signal monitoring by transcranial Doppler and diffusion-weighted magnetic resonance imaging. Characteristics of acute @entity1188 on diffusion-weighted magnetic resonance imaging were categorized according to the number (single or @entity1188 ) and the pattern of @entity385 (cortical, border zone, or perforating @entity1188 ). The data of microembolic signals and diffusion-weighted magnetic resonance imaging were assessed blindly and independently by separate observers. Diffusion-weighted magnetic resonance imaging showed that 15 @entity1 (50%) had single acute @entity385 and 15 @entity1 had multiple acute @entity385 . Among @entity1 with multiple acute @entity1188 , unilateral, deep, chainlike border zone @entity1188 were the most common pattern (11 @entity1 , 73%), and for single @entity1188 , penetrating @entity1188 were the most common (10 @entity1 , 67%). Microembolic signals were detected in 10 @entity1 (33%). The median number of microembolic signals per 30 minutes was 15 (range, 3-102). Microembolic signals were found in 9 @entity1 with @entity1188 and in 1 @entity1 with a single @entity1188 (p = 0.002, chi(2)). The number of microembolic signals predicted the number of acute @entity1188 on diffusion-weighted magnetic resonance imaging (linear regression, adjusted R(2) =0.475, p < 0.001). Common @entity64 mechanisms in @entity1 with @entity2500 are the occlusion of a single penetrating artery to produce a small subcortical lacuna-like @entity1188 and an @entity1416 with @entity73 that produces multiple small @entity385 , especially along the border zone region.

Mechanisms of acute XXXX in @entity1 with @entity2500 : a diffusion-weighted imaging and microemboli monitoring study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity2500 :: ('MESH:D020244', 'Disease') :: ['middle cerebral artery stenosis'] @entity73 :: ('MESH:D003072', 'Disease') :: ['impaired clearance of emboli'] @entity1416 :: ('MESH:D020762', 'Disease') :: ['artery-to-artery embolism'] @entity887 :: ('MESH:D004617', 'Disease') :: ['embolism'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['artery infarcts', 'multiple infarcts', 'infarcts', 'infarct', 'artery territory infarcts'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke', 'cerebral infarcts']
@entity385 :: (MESH:D002544,Disease) :: ['cerebral infarctions']
