BACKGROUND: Malignant @entity82 has been regarded as the most common @entity242 of older adults. However, recent opinion regards @entity1418 as an undifferentiated high grade @entity242 not otherwise classifiable utilizing current techniques available in surgical pathology. Notwithstanding controversy regarding its nomenclature, @entity1418 involving the penis is exceedingly rare, with only 4 cases previously described, to our knowledge. CASE: An uncircumcised 73-year-old male presented with a painless, granular, partially @entity39 lesion beneath the penile foreskin. There was no history of @entity2953 , constitutional symptoms or @entity3833 . Examination of penile shaft, testicles, spermatic cord and inguinal lymph nodes were unremarkable. Biopsy revealed a markedly @entity242 . Subsequent, partial penectomy revealed the same lesion with an adjacent area of @entity957 in situ. CONCLUSION: Malignant @entity82 remains a diagnosis of exclusion. The investigation requires extensive @entity5 sampling in search of areas of differentiation and a complete battery of immunohistochemical markers. Therapeutically important entities in the differential diagnosis that must be ruled out include other poorly differentiated @entity242 , @entity957 and @entity320 .

Malignant XXXX of the glans penis: a case report.

@entity82 :: ('MESH:D005355', 'Disease') :: ['fibrous histiocytoma'] @entity2953 :: ('MESH:D012749', 'Disease') :: ['sexually transmitted disease'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma', 'sarcomas', 'pleomorphic sarcoma'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrotic'] @entity1418 :: ('MESH:D051677', 'Disease') :: ['malignant fibrous histiocytoma', 'pleomorphic malignant fibrous histiocytoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma', 'sarcomatoid squamous cell carcinoma'] @entity3833 :: ('MESH:D053159', 'Disease') :: ['dysuria'] @entity320 :: ('MESH:D008545', 'Disease') :: ['desmoplastic melanoma']
@entity82 :: (MESH:D005355,Disease) :: ['fibrous histiocytoma']
