The diagnosis of @entity213 is usually made by visual identification. Searching for a non-invasive optical diagnostic method with the ability to detect the @entity1613 or second @entity5 earlier in high-risk populations led to the development of photodiagnosis by autofluorescence (AF) endoscopy. The aim of the present study was to evaluate and discuss the diagnostic potential of autofluorescence videoendoscopy as a complementary visual aid in the routine endoscopic diagnosis of @entity135 . In a prospective study, 48 @entity1 underwent white light (WL) videoendoscopy followed by AF technique at the Institute of Gustave-Roussy from November 2001 to August 2002. Of 48 @entity1 , 30 had suspected precancerous or cancerous laryngeal lesions, 7 presented benign laryngeal lesions, while 8 showed pharyngeal and 3 oral @entity5 . All detected lesions were evaluated by histological examination. AF was induced by filtered blue light of a xenon short arc lamp and processed by a CCD camera system (D-Light AF System; Storz, Tuttlingen, Germany). Normal laryngeal mucosa displayed a typical green fluorescence signal. Moderate and severe @entity5115 , @entity2735 and @entity189 showed a diminished green fluorescence and presented a marked reddish-blue color. In case of @entity5656 a bright white color was detected. Some benign lesions, such as @entity738 , @entity1127 and @entity1185 also displayed altered green fluorescence. Autofluorescence videoendoscopy for photodiagnosis of @entity213 has proved to be a method of high specificity and good sensitivity. Two additional @entity1613 that were invisible at the WL examination but detected with the AF technique show its potential role in the regular screening procedure or follow-up examination in a high-risk population. It was a very helpful complementary visual aid for the intraoperative control of the surgical margins after per oral endoscopic resection.

Autofluorescence videoendoscopy for photodiagnosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck cancers'] @entity5115 :: ('MESH:C567703', 'Disease') :: ['epithelial dysplasia'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity2735 :: ('MESH:D002278', 'Disease') :: ['carcinoma in situ'] @entity738 :: ('MESH:D006099', 'Disease') :: ['granulomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumors', 'tumors'] @entity5656 :: ('MESH:D017488', 'Disease') :: ['hyperkeratosis'] @entity1185 :: ('MESH:D010212', 'Disease') :: ['papillomas'] @entity189 :: ('MESH:D002277', 'Disease') :: ['invasive carcinoma'] @entity1613 :: ('MESH:D011230', 'Disease') :: ['precancerous lesions'] @entity213 :: ('MESH:C535575', 'Disease') :: ['head and neck squamous cell carcinomas', 'head and neck squamous cell carcinoma']
@entity213 :: (MESH:C535575,Disease) :: ['head and neck squamous cell carcinoma']
