BACKGROUND: @entity1 who undergo cardiac surgery appear to be at increased risk for the development of @entity580 ( @entity580 ). The development of antibiotic-resistant infections has been associated with significantly greater hospital mortality rates compared to similar infections caused by antibiotic-sensitive pathogens. OBJECTIVES: The purpose of this study is survey of @entity22412 and antibiotic resistance patterns of causative bacteria among @entity1 who underwent open heart surgery in the north of Iran during a 2-year period between September 2012 and September 2014. METHODS: In this cross-sectional study we evaluated 187 @entity1 that underwent open heart surgery with @entity580 . Demographic feature, clinical characteristics and risk factors of each @entity281 were recorded. The antibiotic susceptibility test was performed using the Minimum inhibitory concentration (MIC) method according to the standard protocol of Clinical _ Laboratory Standards Institute (CLSI). Detection of Extended-spectrum beta-lactamase (ESBL) producing bacteria was performed by the double-disk synergy (DDS) test; also @entity3256 -resistant @entity794 ( @entity794 ) strains were identified by @entity794 Screen Agar. The collected data were analyzed using the SPSS software (ver. 16) and, descriptive statistics were used. RESULTS: Out Of total of 2253 hospitalized @entity1 who underwent open heart surgery, 187(5.05%) @entity1 had @entity580 . 51.9% of the @entity1 were female. The rates of @entity281 ( @entity281 ), respiratory tract @entity281 , @entity884 , @entity293 ( @entity293 ), @entity1503 and @entity1764 were 27.80, 25.66%, 17.64, 17.11% 8.55% and 3.20% respectively. @entity526 and @entity794 were the most causative agents of @entity580 . The rate of ESBL-producing bacteria was 14.28- 71.42% among enterobacteriaceae and the rate of @entity794 was 54.2% among @entity794 strains. All isolated Acinetobacter.spp were Multi-drug resistance (MDR). CONCLUSIONS: We showed that the rate of @entity580 among these high-risk @entity1 was in the average level. But the emergence of @entity794 and ESBL bacteria is increasing in our region.

Resistance Pattern of Antibiotics in @entity1 Underwent Open Heart Surgery With XXXX in North of Iran.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity3256 :: ('MESH:D008712', 'Chemical') :: ['Methicillin'] @entity794 :: ('1280', 'Species') :: ['MRSA', 'Staphylococcus', 'S.aureus'] @entity1764 :: ('MESH:D008480', 'Disease') :: ['mediastinitis'] @entity22412 :: ('CHEBI:53204', 'Chemical') :: ['Nis'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'surgical site infection', 'SSI'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['blood Infection'] @entity580 :: ('MESH:D003428', 'Disease') :: ['NIs', 'Nosocomial infections'] @entity293 :: ('MESH:D014552', 'Disease') :: ['UTI', 'Urinary tract infection'] @entity526 :: ('562', 'Species') :: ['E.coli'] @entity884 :: ('MESH:D004696', 'Disease') :: ['endocarditis']
@entity580 :: (MESH:D003428,Disease) :: ['Nosocomial Infection']
