INTRODUCTION: @entity64 is a major health problem and @entity4905 ( @entity4905 ) is an important risk factor for @entity64 . Primary prevention of @entity64 and @entity4905 will have the greatest impact on reducing the burden of these conditions. Evidence-based guidelines for @entity64 / @entity4905 prevention identify individuals eligible for preventative interventions in primary care. This study will investigate: (1) the proportion of @entity64 /TIAs with prior missed opportunities for prevention in primary care; (2) the influence of @entity1 characteristics on missed prevention opportunities and (3) how the proportion of missed prevention opportunities has changed over time. METHODS AND ANALYSIS: A retrospective case review will identify first-ever @entity64 and @entity1 with @entity4905 between 2000 and 2013 using anonymised electronic medical records extracted from @entity283 ( @entity283 ) database. Four categories of missed opportunities for @entity64 / @entity4905 prevention will be sought: untreated high blood pressure in @entity1 eligible for treatment (either blood pressure >= 160/100 or >= 140/90 mm Hg in @entity1 at high @entity65 ( @entity65 ) risk); @entity1 with @entity955 with @entity64 risk and no anticoagulant therapy; no lipid modifying drug therapy prescribed in @entity1 at high @entity65 risk or with @entity4310 . The proportion of @entity1 with each missed opportunity and multiple missed opportunities will be calculated. Mixed effect logistic regression will model the relationship between demographic and @entity1 characteristics and missed opportunities for care; practice will be included as a random effect. ETHICS AND DISSEMINATION: @entity283 data collection was approved by the @entity9462 South East Multi-centre Research Ethics Committee (MREC) in 2003. This study was approved by the independent scientific review committee in May 2013. Dissemination of findings has the potential to change practice, improve the quality of care provided to @entity1 and ultimately reduce the incidence of @entity64 and TIAs. Findings will be published in a peer-reviewed journal and disseminated at national and international conferences.

Retrospective case review of missed opportunities for primary prevention of XXXX and @entity4905 in primary care: protocol paper.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['strokes', 'high stroke', 'stroke', 'Stroke'] @entity283 :: ('OMIM:603663', 'Disease') :: ['THIN', 'the health improvement network'] @entity9462 :: ('MESH:C538336', 'Disease') :: ['NHS'] @entity4905 :: ('MESH:D002546', 'Disease') :: ['transient ischaemic attack', 'TIA'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation'] @entity4310 :: ('MESH:D009386', 'Disease') :: ['familial hypercholesterolaemia'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease']
@entity64 :: (MESH:D020521,Disease) :: ['stroke']
