BACKGROUND AND PURPOSE: In @entity1 with @entity8 ( @entity8 ), @entity45 ( @entity45 ) has been proposed as a means to relieve chronic cyst-related @entity158 . We present our 7-year experience with @entity45 for @entity8 with regard to @entity158 relief, @entity101 , and renal function. @entity1 AND METHODS: Between August 1994 and February 2001, 29 @entity8 @entity1 with @entity1118 (N=29), @entity101 (N=21), and @entity177 (N=10) underwent 35 @entity45 procedures. Every detectable cyst within 2 mm of the renal surface was treated. @entity158 relief was assessed using a @entity158 analog scale; relative @entity158 relief (RPR) equaled (preoperative @entity158 score) - ( @entity282 score)/(preoperative @entity158 score). @entity101 was evaluated using the antihypertensive therapeutic index (ATI): [(dose of blood pressure medication 1/max dose 1) + (dose med 2/max dose 2) + etc.] x 10. Renal function was assessed using the Cockcroft and Gault formula for @entity1011 clearance. RESULTS: The mean operating room time was 4.9 hours (range 2.6-6.6 hours) with no conversions to open surgery. An average of 220 cysts (range 4-692) were treated per @entity1 . The mean follow-up was 32.3 months (range 6-72 months). The RPR was 58%, 47%, and 63% at 12, 24, and 36 months, respectively. At 12, 24, and 36 months, 73%, 52%, and 81% of @entity1 , respectively, noted >50% improvement in their @entity158 compared with the preoperative situation. Five @entity1 became normotensive, and @entity1 improved their ATI by an average of 49% (range 11%-93%). However, six @entity1 had worsening @entity101 , with an ATI increase averaging 53% (range 11%-122%), and one @entity1 who was not hypertensive preoperatively has since developed @entity101 . The @entity1011 clearance changed +4%, +7%, and -2% at 12, 24, and 36 months, respectively. Only one @entity1 had a >20% increase in @entity1011 clearance. The only @entity1 with a >20% decrease in @entity1011 clearance were those who had a @entity1011 clearance <30 mg/dL preoperatively (average decrease 34% [range 20%-51%]). CONCLUSIONS: For @entity8 @entity1 with debilitating @entity158 , extensive @entity45 can provide durable relief. In the majority of @entity1 with @entity158 and @entity101 , a marked improvement in blood pressure also occurs. Cyst decortication was not associated with worsening renal function; indeed, renal function remained largely unchanged over the 3-year follow-up period.

Laparoscopic cyst decortication in XXXX : impact on @entity158 , @entity101 , and renal function.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity8 :: ('MESH:D007674', 'Disease') :: ['autosomal dominant polycystic kidney disease', 'ADPKD'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'Hypertension'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal insufficiency'] @entity45 :: ('MESH:D010181', 'Disease') :: ['laparoscopic cyst decortication', 'LCD'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity1118 :: ('MESH:D059350', 'Disease') :: ['chronic pain']
@entity8 :: (MESH:D007674,Disease) :: ['autosomal dominant polycystic kidney disease']
