BACKGROUND: The high incidence of @entity356 among the octogenarians and nonagenarians (oldest old; age >=  80 years) is emerging as an important management issue. Herein, we report both the short-term outcomes and long-term survival results of standard radical gastrectomy in this group of @entity1 . METHODS: This was a retrospective review of 164 oldest old @entity1 (older group) and 2,258 younger @entity1 (age <80 years; younger group) with @entity356 who underwent curative resection between January 1994 and December 2006. Clinicopathologic data, long-term survival, and prognostic factors were analyzed. RESULTS: Clinical @entity5 stage did not differ between the two groups at the time of diagnosis. Higher Charlson comorbidity index scores (>=  5) were observed in the older group than in the younger group; this was associated with higher postoperative morbidity (P = 0.035) and in-hospital mortality rates (P = 0.015) in the older group. At a median follow-up of 37.8 months, the overall survival rate for the older group was lower than that for the younger group (P < 0.001). However, the cumulative incidence of @entity356 was comparable between the two groups. Nodal involvement and metastatic to retrieved lymph node ratio were the only independent predictors of survival in the older group. CONCLUSIONS: @entity1 in the older group had a higher postoperative morbidity rate but comparable @entity5 -specific survival. Careful @entity1 selection for gastrectomy is warranted in elderly @entity1 , particularly those with high-grade nodal involvement.

Standard radical gastrectomy in octogenarians and nonagenarians with XXXX : are short-term surgical results and long-term survival substantial?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'gastric cancer-related deaths']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
