OBJECTIVE: To describe the clinical course of individuals with @entity1723 after a mean of 5 years from diagnosis and to compare glycemic control between those treated with diet and/or oral agents and those treated with insulin at follow-up. RESEARCH DESIGN AND METHODS: Medical records of @entity1 with new-onset @entity6 , who presented with unprovoked @entity6 , were reviewed. A total of 54 of these individuals were traceable and had relevant data collected within the past 2 years. All @entity1 had nonsusceptibility HLA haplotypes and no serological evidence of @entity12011 . Most of these @entity1 were male (41 @entity1 and 13 @entity1 ), were non-Caucasian, were @entity28 at the time of diagnosis (BMI 31.6 +/- 6.3 kg/m(2)), reported @entity353 (12.8 +/- 9.8 kg), had a family history of type 2 @entity6 , and had acanthosis nigricans. At follow-up, 33 @entity1 were still taking insulin and 21 were on diet and/or oral-agent therapy. RESULTS: Both treatment groups were similar in clinical presentation and demographics at diagnosis. After 4.8 +/- 1.6 years of follow-up, the 33 @entity1 that were receiving insulin had a lower HbA(1c) than the 21 @entity1 who were using therapies other than insulin (7.8 +/- 2.4 vs. 11.1 +/- 3.5%, P = 0.009; 95% CI 1.0-6.5%). There was a high correlation between change in weight and change in HbA(1c) at follow-up (r = 0.45, P < 0.001, n = 54). There were no differences in the rate of @entity2412 or in the episodes of recurrent @entity6 . CONCLUSIONS: @entity1723 more frequently in male African-American @entity1 but also occurs in other ethnic groups. @entity1 with @entity1723 who continued to use insulin had better glycemic control than @entity1 using therapies other than insulin. Regained weight is a good clinical marker for improvement in glycemic control. Individuals with this type of @entity6 should not be switched to therapies other than insulin.

XXXX in Dallas, Texas: a 5-year experience.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity12011 :: ('MESH:C565730', 'Disease') :: ['autoimmune type 1 diabetes'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic ketoacidosis', 'diabetes'] @entity1723 :: ('MESH:D003922', 'Disease') :: ['idiopathic type 1 diabetes', 'Idiopathic type 1 diabetes occurs'] @entity2412 :: ('MESH:D048909', 'Disease') :: ['diabetes complications']
@entity1723 :: (MESH:D003922,Disease) :: ['Idiopathic type 1 diabetes']
