BACKGROUND: Cryptosporidium is an intracellular protozoan organism which causes @entity294 , both in immunocompetent and immunocompromised hosts. Renal transplant recipients are prone to develop a variety of @entity281 . OBJECTIVES: The aim of this study was to determine the prevalence of cryptosporidiosis in our renal transplant recipients presenting with acute @entity294 . @entity1 AND METHODS: During six months of the study, 644 renal transplant recipients presented with acute @entity294 . Single stool sample was obtained for detailed analysis including gross and microscopic examination for red blood cells, pus cells, ova, cysts, and protozoa. The modified Ziehl-Neelsen (ZN) staining was done to identify the oocysts of cryptosporidia. RESULTS: Out of 644 renal transplant @entity1 , oocysts of cryptosporidia were identified in 343 @entity1 (53%). Detailed stool analysis of these @entity1 showed the presence of numerous pus cells in 27 (7.9%) @entity1 , @entity325 with @entity461 cysts in 15 (4.3%), and @entity2330 cysts in 10 (2.9%). In all, out of 343 @entity1 , 43 (12.5%) had dual infection with bacteria and protozoa in addition to cryptosporidiosis. CONCLUSIONS: Cryptosporidium is an important pathogen causing acute @entity294 in renal transplant recipients in our set up. Stool examination is usually negative for pus cells. It is recommended that in all transplant recipients presenting with acute @entity294 modified ZN staining should be done to rule out cryptosporidiosis in highly endemic areas like Pakistan.

Prevalence of cryptosporidiosis in renal transplant recipients presenting with acute XXXX at a single center in Pakistan.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections including protozoal infections'] @entity2330 :: ('5759', 'Species') :: ['entamoeba histolytica'] @entity325 :: ('MESH:D060085', 'Disease') :: ['co-infection'] @entity461 :: ('5741', 'Species') :: ['giardia intestinalis']
@entity294 :: (MESH:D003967,Disease) :: ['diarrhea']
