OBJECTIVE: The objective was to investigate disability and health-related quality-of-life (HRQoL) 3, 6 and 12 months after @entity131 ( @entity131 ) in non-geriatric (<=  65 years) and geriatric @entity1 (> 65 years). METHODS: @entity1 >=  16 years who sustained a severe @entity131 (Abbreviated Injury Scale of the head region > 3) were included in this prospective, multi-centre study. Outcome measures were Glasgow Outcome Scale Extended (GOSE; disability), SF-12 (HRQoL). Mixed linear model analyses were performed. RESULTS: Three hundred and fifty-one @entity1 (median age = 50 years; interquartile range (IQR) = 27-67) were included; 73.2% were male and 27.6% were geriatric @entity1 . Median GOSE at 3, 6 and 12 months was 5 (IQR = 3-7), 6 (IQR = 4-8) and 7 (IQR = 5-8); this increase (slopetime = 0.22, p < 0.0001) was age dependent (slopeage*time = -0.06, p = 0.003). Median SF-12 physical component scale score at 3, 6 and 12 months was 42.1 (IQR = 33.6-50.7), 46.6 (IQR = 37.4-53.9) and 50.4 (IQR = 39.2-55.1); this increase (slopetime = 1.52, p < 0.0001) was not age dependent (slopeage*time = -0.30, p = 0.083). SF-12 mental component scale scores were unchanged. CONCLUSIONS: Disability decreased and HRQoL improved after @entity131 between 3-12 months. In geriatric @entity1 this improvement was relevant for HRQoL only.

Trajectory of disability and quality-of-life in non-geriatric and geriatric survivors after severe XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity131 :: ('MESH:D001930', 'Disease') :: ['traumatic brain injury', 'TBI']
@entity131 :: (MESH:D001930,Disease) :: ['traumatic brain injury']
