BACKGROUND AND OBJECTIVES: We assessed the cumulative incidence, symptoms, and risk factors for @entity2045 in @entity0 and @entity320 @entity1 undergoing sentinel lymph node biopsy or axillary lymph node dissection. METHODS: @entity1 were recruited preoperatively (time 0) and assessed at 6, 12, and 18 months postoperatively. Limb volume change (LVC) was measured by perometry. @entity4269 was categorized as none, mild (LVC 5-9.9%), or moderate/severe (LVC>= 10%). Symptoms were assessed with a validated @entity4269 instrument. Longitudinal logistic regression analyses were conducted to identify risk factors associated with moderate/severe @entity4269 . RESULTS: Among 205 @entity0 and 144 @entity320 @entity1 , the cumulative incidence of moderate/severe @entity4269 at 18 months was 36.5% and 35.0%, respectively. However, in adjusted analyses, factors associated with moderate/severe @entity4269 were @entity0 (OR 2.0, P   =   0.03), body mass index >= 30   kg/m(2) (OR 1.6, P   =   0.04), greater number of lymph nodes removed (OR 1.05, P   <   0.01), and longer interval since surgery (OR 2.33 at 18 months, P   <   0.01). CONCLUSIONS: @entity4269 incidence increased over time in both cohorts. However, the adjusted risk of moderate/severe @entity4269 was two-fold higher in @entity0 @entity1 . These results may be attributed to surgical treatment of the @entity5 in the breast and more frequent use of radiation. J. Surg. Oncol.    2015 Wiley Periodicals, Inc.

The long-term risk of @entity2045 is two-fold higher in XXXX @entity1 than in @entity320 @entity1 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity2045 :: ('MESH:D009207', 'Disease') :: ['upper-extremity lymphedema'] @entity5 :: ('MESH:D009369', 'Disease') :: ['primary tumor'] @entity4269 :: ('MESH:D008209', 'Disease') :: ['Lymphedema', 'lymphedema'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
