Forty-two @entity1 with probable @entity195 ( @entity195 ) and 18 elderly healthy controls underwent quantitative EEG (qEEG) and regional cerebral blood flow (rCBF; 133Xe clearance) examinations. Correlations were sought between relative qEEG band powers and percent rCBF values in a posterior temporoparietal region of interest in either hemisphere. Moreover, stepwise discriminant analysis was applied to study the accuracy of the two techniques in differentiating @entity195 from healthy ageing. rCBF and qEEG were correlated with one another, especially in the right hemisphere (p values ranging from <0.001 to <0.01). Significant correlations were found between Mini Mental State Examination (MMSE) and relative power of both the 2- to 6-Hz and the 6.5- to 12-Hz bands on either side (p < 0.001), and between MMSE and left rCBF (p < 0.005), while the correlation with right rCBF was poorer (p < 0.02). The statistical procedure identified the right values of both examinations for the discriminant analysis. Sensitivity of qEEG and rCBF employed together was 88% and specificity 89%, with a total accuracy of 88.3%. The unrecognized @entity1 (n = 5) were affected by mild @entity195 (4 scoring 3 at the Global Deterioration Scale @entity196 ). qEEG alone showed an accuracy of 77% in the whole group and of 69% in mild @entity195 , and rCBF alone an accuracy of 75% in the whole group and of 71% in mild @entity195 . It is concluded that qEEG and rCBF examinations employed together are accurate tools to differentiate @entity195 from normal ageing, although a lower degree of accuracy is achieved in mildly demented @entity1 .

Quantitative electroencephalography and regional cerebral blood flow: discriminant analysis between Alzheimer's XXXX and healthy controls.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity196 :: ('MESH:D020754', 'Disease') :: ['and 1 scoring 4'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"]
@entity1 :: (9606,Species) :: ['patients']
