OBJECTIVE: To determine whether @entity5 angiogenesis correlates with progression of @entity356 . METHOD: Microvessel counts (MVC) of 131 specimens resected from @entity1 with @entity356 were investigated by immunohistological staining with a monoclonal antibody against F-VIII RAg, counting the mean number of microvessels in the five areas of highest vascular density under 200 times magnification microscopy. Correlation among MVC, various clinicopathologic factors, and prognosis was studied. RESULT: MVC increased with @entity2802 stage, the MVC of @entity1 with advanced stage disease was significantly higher than that of early stage @entity1 (P < 0.01). MVC was significantly higher in @entity5 with deep penetration (P < 0.05), lymph node @entity3 (P < 0.001) and distant @entity3 (P < 0.05) than in those without invasion and such @entity3 . The recurrence rate after curative resection in hypervascular group (MVC > or 16) was 58.4%, which was significantly higher (P < 0.05) than that in the hypovascular group (MVC < 16). Moreover, the prognosis of @entity1 with a high MVC was significantly poorer than that of those with a low MVC. The probability of 5 year survival rate was estimated by P = e(1.6231-0.1036 x MVC)/1 + e(1.6231-0.1036 x MVC). Multivariate analysis indicated that MVC is an independent prognostic factor in @entity356 . CONCLUSION: Angiogenesis within @entity356 is an indicator of @entity5 behavior and may identify @entity1 at higher risk for recurrence and poorer prognosis.

[Prognostic value of XXXX vascularity in @entity356 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity2802 :: ('10178', 'Gene') :: ['TNM'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer', 'gastric carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
