BACKGROUND: @entity7492 is the most common benign, self-limiting @entity5 of childhood. Treatment is reserved for @entity2695 that obstruct vital structures or cause significant disfigurement. Traditionally, @entity288 have been the medical treatment of choice. Since 2008, however, @entity1169 has been rapidly adopted as an effective pharmacological treatment for @entity7492 . Published data regarding the long-term side effects of @entity1169 are currently lacking. OBJECTIVE: To describe the long-term effects of @entity1169 and @entity288 on anthropometric measurements (height, body mass index [BMI]) and blood pressure in @entity1 . METHODS: A prospective database analysis of all @entity7492 @entity1 visits to the @entity455 clinic at the authors' institution between October 2007 and February 2012 was performed. Anthropometric measures (height and BMI) and blood pressure were analyzed. RESULTS: A total of 290 visits (119 @entity1 ) to the @entity455 clinic were reviewed. Of these, 18 @entity1 received medical treatment and their anthropometry was analyzed. BMI percentile increased significantly in @entity1 treated with @entity288 (P=0.0039). @entity228 treatment also resulted in a significant decrease in height percentile (P=0.0078). Anthropometric measures did not cross percentiles in @entity1 treated with @entity1169 . A significant @entity551 was noted in the @entity1169 group (P=0.03), but no @entity551 values were recorded. Median treatment duration was significantly longer when @entity1 received @entity1169 (372 versus 133 days; P=0.0033). CONCLUSION: @entity1169 for the treatment of @entity455 does not share the unfavourable effects on @entity1 anthropometry that @entity288 exhibit; however, a longer duration of therapy is required.

XXXX therapy for @entity7492 is less toxic but longer in duration than corticosteroid therapy.

@entity1169 :: ('MESH:D011433', 'Chemical') :: ['propranolol', 'Propranolol'] @entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity455 :: ('MESH:D014652', 'Disease') :: ['pediatric vascular abnormality', 'infantile vascular abnormalities'] @entity2695 :: ('MESH:D006391', 'Disease') :: ['hemangiomas'] @entity7492 :: ('MESH:C535860', 'Disease') :: ['Infantile hemangioma', 'infantile hemangioma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['Corticosteroid'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotensive', 'decrease in systolic blood pressure'] @entity288 :: ('MESH:D000305', 'Chemical') :: ['corticosteroids']
@entity1169 :: (MESH:D011433,Chemical) :: ['Propranolol']
