BACKGROUND: Evidence suggests that @entity146 and explosive anger are common among individuals with @entity148 ; yet, the influence of @entity23 ( @entity23 ) on the onset, course, consequences, and patterns of comorbidity among those with @entity148 is unknown. METHODS: Data were drawn from the National Comorbidity Survey Replication (N = 9,282) and Adolescent Supplement (N = 9,632), nationally representative surveys conducted between 2001 and 2004. Diagnoses were based on structured lay-administered interviews. Lifetime diagnoses were assessed with structured instruments. Outcomes included comorbidity, functional and @entity73 , and treatment utilization. RESULTS: Adolescents with a lifetime @entity148 had a higher prevalence of a lifetime anger attacks (68.5%) and @entity23 (22.9%) than adolescents without a lifetime @entity148 (48.6 and 7.8%, respectively), especially @entity913 and @entity4697 . Similar elevation was found for adults. Age of onset and course of @entity148 did not differ by @entity23 . Severe functional impairment associated with @entity148 was higher among adolescents (39.3%) and adults (45.7%) with @entity23 than those without @entity23 (29.2 and 28.2%, respectively). Comorbidity for all other disorders was elevated. However, individuals with @entity148 and @entity23 were no more likely to use treatment services than those with @entity148 without @entity23 . CONCLUSIONS: Individuals with @entity23 concomitant to @entity148 , especially @entity913 and @entity4697 , are at marked risk for worse functional impairment and a higher burden of comorbidity, but onset and course of @entity148 do not differ, and those with @entity148 and @entity23 are no more likely to utilize treatment services. Assessment, identification, and specialized treatment of anger in the context of @entity148 are critical to reducing burden.

ANXIOUS AND AGGRESSIVE: THE CO-OCCURRENCE OF XXXX WITH ANXIETY DISORDERS.

@entity4697 :: ('MESH:D016584', 'Disease') :: ['panic', 'panic disorders'] @entity146 :: ('MESH:D001523', 'Disease') :: ['impulsive aggression'] @entity913 :: ('MESH:D010698', 'Disease') :: ['social phobia'] @entity73 :: ('MESH:D003072', 'Disease') :: ['role impairment'] @entity23 :: ('MESH:D007174', 'Disease') :: ['IED', 'intermittent explosive disorder'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety disorder', 'anxiety', 'anxiety disorders']
@entity23 :: (MESH:D007174,Disease) :: ['IED']
