UNASSIGNED: Polymorphisms in the promoter region of @entity5750 gene have been associated with @entity565 and atopy although the findings between cohorts have not been uniform. We aimed at investigating the association between @entity5750 gene ( @entity68744 ) polymorphism and bronchial @entity565 in Egyptian @entity1 . Genotyping of @entity5750 gene ( @entity68744 ) polymorphism was done by real-time PCR in 192 asthmatic @entity1 ( @entity1097 , n  =  100 and non- @entity1097 , n  =  92) and 181 age- and gender-matched healthy children. Serum levels of total IgE were measured by ELISA. Skin prick test was performed on all @entity1 . We found that the frequency of AA genotype was significantly higher in asthmatic @entity1 compared to healthy controls. Asthmatic @entity1 carrying GG genotype had a significantly lower prevalence of @entity12131 . Meanwhile, the "A" allele was significantly higher in @entity1097 asthmatic @entity1 compared to healthy and non- @entity1097 @entity1 . Moreover, @entity1097 @entity1 carrying the "G" allele showed better @entity565 control. In conclusion, our findings represent an evidence for the role of @entity5750 gene ( @entity68744 ) polymorphism in childhood @entity565 and @entity565 control.

Association Between @entity5750 Polymorphism ( @entity68744 ) and Childhood XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity68744 :: ('c|SUB|G|-1145|A', 'DNAMutation') :: ['-1145G/A'] @entity12131 :: ('MESH:C565292', 'Disease') :: ['atopic asthma'] @entity5750 :: ('929', 'Gene') :: ['CD14'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity1097 :: ('MESH:C566404', 'Disease') :: ['atopic']
@entity565 :: (MESH:D001249,Disease) :: ['Bronchial Asthma']
