@entity1184 of a single functioning kidney is well described and has been shown to occur in utero. The long-term effects of @entity1184 and hyperfiltration in this situation are unknown. This study defined the growth parameters for single kidneys during childhood and correlated them with inulin clearance. @entity1 were those who had a radiologically "normal" single kidney, where the contralateral kidney was known to be non-functioning from infancy. Data were obtained from 74 @entity1 (40 @entity1 and 34 @entity1 ) drawn from a registry of cases with a single kidney, and in whom simultaneous measurements of inulin clearance and @entity8 had been made at around 5, 10, and 16 years of age. @entity8 was taken as the maximal bipolar measurement using real-time ultrasound scan. Inulin clearance was by continuous infusion technique. Nomograms for single kidney growth were determined against age, height, weight, and body surface area. Renal growth was correlated with inulin clearance. @entity8 was found to correlate best with body surface area ( r=0.85, P<0.001), but this was not significantly superior to correlations with age, height, or weight separately. Inulin clearance per body surface area correlated positively with standardized @entity8 , i.e., Z score for @entity8 normalized for body surface area ( r=0.53, P<0.001). The larger kidneys have a higher glomerular filtration rate. Provided that the nephron number in the single kidney is similar to that in a paired kidney, single kidneys are hypertrophied and the single nephron glomerular filtration rate is likely to be abnormally high in these @entity1 .

XXXX and inulin clearance in the radiologically normal single kidney.

@entity1184 :: ('MESH:D006984', 'Disease') :: ['Compensatory hypertrophy', 'hypertrophy'] @entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'girls', 'boys'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal length', 'Renal length']
@entity8 :: (MESH:D007674,Disease) :: ['Renal length']
