A series of 91 @entity1 operated on for @entity137 was followed systematically during 24 months post-operatively with regard to thyroid function. A thyroid remnant of at least 5 to 8 g was left in the majority of cases, and thyroid replacement was not given. Histopathological grading was performed on goitrous specimens with reference to @entity2617 . Thyroglobulin antibodies and thyroid microsomal antibodies were determined pre-operatively. Goitre resection provoked a high, but transient increase in serum thyroid stimulating hormone (TSH) levels with peak values 3 to 6 months after operation. Twenty-four months after surgery serum TSH values had normalized, but were still slightly elevated in @entity1 with bilateral surgery and high @entity2617 , 9% of the @entity1 . The concentration of serum free @entity1955 index (FT4I) and serum total @entity1954 (TT3) decreased after operation, but within reference range. Twenty-four months after surgery, serum FT4I was back to baseline values, while serum TT3 was still lowered compared to the pre-operative level. None of the @entity1 developed @entity1375 . Occurrence of circulating thyroid autoantibodies was not related to post-operative changes in thyroid parameters. We conclude that thyroid replacement therapy seems not to be indicated routinely following resection for @entity137 , but precaution should be taken in case of bilateral resection and high @entity2617 of goitrous specimens.

Thyroid function after resection for XXXX with special reference to thyroid lymphocytic aggregation and circulating thyroid autoantibodies.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1375 :: ('MESH:D007037', 'Disease') :: ['overt hypothyroidism'] @entity137 :: ('MESH:D064420', 'Disease') :: ['non-toxic goitre'] @entity2617 :: ('MESH:D017254', 'Disease') :: ['lymphocytic infiltration'] @entity1955 :: ('MESH:D013974', 'Chemical') :: ['thyroxine'] @entity1954 :: ('MESH:D014284', 'Chemical') :: ['triiodothyronine']
@entity137 :: (MESH:D064420,Disease) :: ['non-toxic goitre']
