PURPOSE: To assess the clinical benefit of @entity419 Positron Emission Tomography/Computed Tomography ( @entity419 -PET/CT) in evaluating pelvic lymph nodes in @entity1 with early @entity5 (FIGO stage 1a-1b1), who have magnetic resonance imaging (MRI)-defined lymph node negative disease, with histopathologic results as the reference standard. MATERIALS AND METHODS: We assessed one hundred and seventy nine sequential @entity419 -PET/CT scans in @entity1 with newly diagnosed @entity2622 between January 2009 and September 2011. 47 of these @entity1 had early stage disease (FIGO stage 1a-1b1) with no suspicious lymph nodes on MRI. @entity419 -PET/CT images were analyzed and histopathological findings (pelvic lymph node resection) served as the reference standard. RESULTS: The median age of @entity1 was 48 (range 22-86) years. 66  % had squamous histotype. Median number of nodes dissected per @entity1 was 21 (range 8-47), 2 of 47 @entity1 had nodal metastases (4.25  %). All @entity1 in this group had no suspicious lymph nodes on @entity419 -PET/CT. Overall @entity1 based sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of @entity419 -PET/CT for detection of @entity66 were 0  %, 100  %, 0  %, 96  %, and 96  % respectively. CONCLUSION: Pathologic validation of @entity419 -PET/CT imaging demonstrates little value for @entity419 -PET/CT in @entity1 with early stage (FIGO stage 1a-1b1) MRI-defined lymph node negative @entity2622 . Since the likelihood of metastatic @entity66 is very low in @entity1 with stage 1a-1b1 cervical @entity5 , we believe that @entity419 -PET/CT should not have a role in the routine pre-treatment evaluation of these @entity1 .

@entity419 -PET/CT is of limited value in primary staging of early XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity419 :: ('MESH:D019788', 'Chemical') :: ['18F-Fluorodeoxyglucose', '18F-FDG'] @entity66 :: ('MESH:D004194', 'Disease') :: ['nodal disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'stage cervical cancer'] @entity2622 :: ('MESH:D002583', 'Disease') :: ['cervical carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['stage cervical cancer']
