OBJECTIVES: To evaluate the effects of exercise on @entity5 -related @entity4269 and related symptoms, and to determine the need for those with @entity4269 to wear compression during exercise. DATA SOURCES: CINAHL, Cochrane, EBSCOhost, MEDLINE, PubMed, ProQuest Health and Medical Complete, ProQuest Nursing and Allied Health Source, ScienceDirect, and SPORTDiscus databases were searched for trials published before January 1,  2015. STUDY SELECTION: Randomized and nonrandomized controlled trials and single-group pre-post studies published in English were included. Twenty-one (exercise) and 4 (compression and exercise) studies met inclusion criteria. DATA EXTRACTION: Data were extracted into tabular format using predefined data fields by 1 reviewer and assessed for accuracy by a second reviewer. Study quality was evaluated using the Effective Public Health Practice Project Quality Assessment Tool. DATA SYNTHESIS: Data were pooled using a random-effects model to assess the effects of acute and long-term exercise on @entity4269 and @entity304 , with subgroup analyses for exercise mode and intervention length. There was no effect of exercise (acute or intervention) on @entity4269 or associated symptoms, with standardized mean differences from all analyses ranging between -0.2 and 0.1 (P  values >= .22). Findings from subgroup analyses for exercise mode (aerobic, resistance, mixed, other) and intervention duration (>12wk or   <=12wk) were consistent with these findings-that is, no effect on @entity4269 or associated symptoms. There were too few studies evaluating the effect of compression during regular exercise to conduct a meta-analysis. CONCLUSIONS: Individuals with secondary @entity4269 can safely participate in progressive, regular exercise without experiencing a worsening of @entity4269 or related symptoms. However, there is insufficient evidence to support or refute the current clinical recommendation to wear compression garments during regular exercise.

Systematic Review and Meta-Analysis of the Effects of Exercise for Those With XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity4269 :: ('MESH:D008209', 'Disease') :: ['lymphedema'] @entity304 :: ('MESH:D010302', 'Disease') :: ['lymphedema-associated symptoms']
@entity5 :: (MESH:D009369,Disease) :: ['Cancer-Related Lymphedema']
