UNASSIGNED: @entity1 suffering from @entity11526 ( @entity11526 ) manifest a dysregulation in hemodynamic response during exercise, with an exaggerated systemic vascular increase. However, it is not clear whether this is the consequence of @entity209 per se or whether it is due to concomitant @entity28 . The aim of the present investigation was to discover whether @entity11526 and non-complicated @entity28 resulted in different hemodynamic responses during the metaboreflex. Twelve metabolically healthy but @entity28 subjects (MHO, 7 @entity1 ), 13 @entity11526 @entity1 (5 @entity1 ), and 12 normal age-matched controls (CTL, 6 @entity1 ) took part in this study. All @entity1 underwent a post-exercise @entity63 protocol to evaluate the metaboreflex activity. Central hemodynamics were evaluated by impedance cardiography. The main result shows an exaggerated increase in systemic vascular resistance from baseline during the metaboreflex in the @entity11526 @entity1 as compared to the other groups (481.6  180.3, -0.52  177.6, and -60.5  58.6 dynes   s-1   cm-5 for the @entity11526 , the MHO, and the CTL group respectively, p<0.05). Moreover, the MHO subjects and the CTL group showed an increase in cardiac output during the metaboreflex (288.7  325.8 and 703.8  276.2 mL   m-1 increase with respect to baseline), whereas this parameter tended to decrease in the @entity11526 group (-350  236.5 mL   m-1). However, the blood pressure response, which tended to be higher in the @entity11526 @entity1 , was not statistically different between groups. The results of the present investigation suggest that @entity11526 @entity1 have an exaggerated vasoconstriction in response to metaboreflex activation and that this fact is not due to @entity28 per se.

Differences in hemodynamic response to metaboreflex activation between XXXX @entity1 with @entity209 and healthy subjects with @entity28 phenotype.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Patients', 'patients'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese', 'obesity'] @entity63 :: ('MESH:D007511', 'Disease') :: ['muscle ischemia'] @entity11526 :: ('MESH:C535554', 'Disease') :: ['obesity and metabolic syndrome', 'OMS'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic syndrome']
@entity28 :: (MESH:D009765,Disease) :: ['obese']
