OBJECTIVE: To assess the association of high-sensitivity C-reactive protein (hsCRP) to adverse @entity65 and perioperative @entity296 in @entity1 after elective vascular surgery. METHODS: This was a prospective observational study in a tertiary-care teaching hospital, with 239 @entity1 undergoing elective vascular surgery. The receiver-operating characteristic (ROC) curve was calculated to assess the optimal cut-off value of hsCRP. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated. Multiple logistic regression analysis was used to identify the predictors of the primary outcome. The primary outcome was a composite of periprocedural @entity296 , defined as @entity6949 ( @entity6949 ) elevation above the decision limit of 0.15  g/L, death, @entity1187 , @entity64 , @entity712 , or intrastent @entity715 within 30 days of surgery. RESULTS: On ROC analysis, the optimal cut-off value of hsCRP was 3.2 mg/L. The primary outcome occurred in 48 @entity1 (20.1%). On univariate analysis, smoking (P = .009), known @entity1007 (P = .01), previous @entity741 (P = .0003), open surgery (P = .03), and hsCRP levels (P < .0001) were associated with the primary outcome. On multiple logistic regression analysis, only hsCRP was independently associated with the primary outcome. The unadjusted and adjusted ORs for the primary outcome among @entity1 with hsCRP levels >3.2 mg/L were 7.5 (CI, 3.7-15.2; P < .0001) and 4.6 (CI, 2.1-9.9; P = .0001), respectively. CONCLUSION: Our data suggest that higher levels of hsCRP are independently associated with an increased risk of perioperative @entity296 and early adverse @entity65 in @entity1 undergoing elective vascular surgery. This may have implications for risk stratification and therapeutic approach.

High-sensitivity C-reactive protein predicts XXXX and @entity296 after vascular surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndrome'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial damage'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity712 :: ('MESH:D006333', 'Disease') :: ['acute heart failure'] @entity1007 :: ('MESH:D006937', 'Disease') :: ['hypercholesterolemia'] @entity6949 :: ('7137', 'Gene') :: ['cTn-I', 'cardiac troponin I'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular events']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular events']
