UNASSIGNED: Microvascular, macrovascular and neurological complications are the key causes of morbidity and mortality among @entity6 (T2DM) @entity1 . The aim of this study was to investigate the alterations of cardiac autonomic function of @entity6 @entity1 in relation to three types of @entity2412 . ECG recordings were collected and analyzed from 169 T2DM @entity1 in supine position who were diagnosed with @entity8 (n = 55), @entity1897 (n = 64) and @entity989 (n = 106) at two hospitals in the UAE. Comparison between combinations of @entity1 with complications and a control @entity6 group (CONT) with no complication (n = 34) was performed using time, frequency and multi-lag entropy measures of heart rate variability (HRV). The results show that these measures decreased significantly (p<0.05) depending on the presence and type of @entity2412 . Entropy, (median, 1st- 3rd interquartile range) for the group combining all complications (1.74,1.37-2.09) was significantly lower than the corresponding values for the CONT group (1.77, 1.39-2.24) with @entity8609 for sequential beat-to-beat changes. Odds ratios (OR) from the entropy analysis further demonstrated a significantly higher association with the combination of @entity989 and @entity1897 versus CONT (OR: 1.42 at lag 8) and an even OR for the combination of @entity989 and @entity8 (OR: 2.46 at lag 8) compared to the other groups with complications. Also, the OR of low frequency power to high frequency power ratio (LF/HF) showed a higher association with these @entity2412 compared to CONT, especially for the @entity1 group combining all complications (OR: 4.92). This study confirms that the type of microvascular or @entity1897 present in T2DM @entity1 have different effects on heart rate entropy, implying disorders of multi-organ connectivity are directly associated with @entity16 . Clinical practice may benefit from including multi-lag entropy for cardiac rhythm analysis in conjunction with traditional screening methods in @entity1 with @entity2412 to ensure better preventive and treatment outcomes in the Emirati Arab population.

Association of XXXX with Heart Rate Variability among a @entity6 Population in the UAE.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity8609 :: ('10715', 'Gene') :: ['lag-1'] @entity8 :: ('MESH:D007674', 'Disease') :: ['nephropathy'] @entity6 :: ('MESH:D003920', 'Disease') :: ['type II diabetes mellitus', 'diabetic'] @entity989 :: ('MESH:D012164', 'Disease') :: ['retinopathy'] @entity16 :: ('MESH:D009422', 'Disease') :: ['autonomic nervous system dysfunction'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral neuropathy complication', 'peripheral neuropathy'] @entity2412 :: ('MESH:D048909', 'Disease') :: ['diabetic-related complications', 'diabetes-related complications', 'diabetic complications']
@entity2412 :: (MESH:D048909,Disease) :: ['Diabetes Related Complications']
