1. Polymers of orosomucoid were produced in two molecular shapes, filamentous (;chain') and spherical (;ball'), by heating the @entity1372 salt of the monomer in either water or high concentrations of @entity2827 . An ;intermediate' state containing both shapes in various proportions was found in preparations obtained by polymerizing orosomucoid in intermediate concentrations of @entity2827 . 2. The filamentous form of polymer was found to inhibit strongly the haemagglutination of some (;sensitive') strains but not of other (;insensitive') strains of @entity683 virus; the ;intermediate' form feebly inhibited haemagglutination by ;sensitive' strains. 3. The filamentous form agglutinated both ;sensitive' and ;insensitive' strains of virus; the other forms of polymer did not. It also inhibited multiplication of both ;sensitive' and ;insensitive' strains when inoculated into embryonated and de-embryonated eggs. 4. The ;intermediate' and spherical forms of the polymer had no effect on the virus multiplication. 5. Polymers of orosomucoid from which neuraminic acid had been split off had no detectable effect on @entity683 viruses.

Effect of polymerized orosomucoid on some strains of XXXX virus.

@entity683 :: ('MESH:D007251', 'Disease') :: ['influenza'] @entity2827 :: ('MESH:D012965', 'Chemical') :: ['sodium chloride'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium']
@entity683 :: (MESH:D007251,Disease) :: ['influenza']
