BACKGROUND: Obesity has been correlated with various adverse events in @entity1 who receive left ventricular assist devices (LVAD). In this study, we sought to further characterize the role of @entity28 in this @entity1 population.Methods   and   Results:We performed a retrospective analysis of 164 @entity1 implanted with a HeartMate II from August 2008 to December 2014. @entity1 were categorized into 2 BMI groups based on WHO guidelines: BMI 18.5-30 kg/m(2)(n=99) and BMI >30 kg/m(2)(n=65). @entity1 demographics, adverse outcome and long-term survival were compared between the 2 groups. For any outcome associated with BMI groups, we performed a Cox regression to identify confounding comorbidities. Preoperative demographics and comorbidities were similar. @entity1 with BMI >30 were younger (P=0.01) and had a higher incidence of @entity164 2 @entity6 (P=0.01). While rate of pump @entity715 was higher among @entity1 with BMI >30 (P=0.02), overall survival at 2 years did not differ. The most common cause of death was @entity64 in the @entity28 group. On multivariable cox regression analysis, BMI was an independent risk factor of pump @entity715 . CONCLUSIONS: Higher BMI does not reduce survival after VAD implantation but it does appear to increase the risk of pump @entity715 . Further studies to characterize the role of BMI in survival and @entity715 rates are warranted.

Higher Body Mass Index Increases Risk of HeartMate II Pump XXXX But Does Not Adversely Affect Long-Term Survival.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'Patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['hemorrhagic stroke'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese', 'obesity'] @entity164 :: ('MESH:D017827', 'Disease') :: ['type'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity715 :: (MESH:D013927,Disease) :: ['Thrombosis']
