INTRODUCTION: @entity2147 ( @entity2147 ) is a @entity395 without established treatment. METHODS: We report 2 @entity2147 medication-responsive cases with typical characteristics of @entity7350 ( @entity7350 ). CASE-REPORTS: A 10 y.o. @entity1 and a 14 y.o. @entity1 presented with @entity25 for 3-9 days (every 2-3 weeks). Physical examination, brain images and blood tests were normal. Polysomnographic findings were heterogenous, including disrupted @entity25 . MSLTs revealed 2-3 SOREMPs and short sleep latency. @entity2049 rendered @entity1 * s sleep normalization, while @entity1090 normalized @entity1 * s sleep cycles. CONCLUSIONS: Facing the absence of clinical trials in @entity2147 , reports of responsive cases are the available therapeutic evidence.

XXXX : Report of medication-responsive cases.

@entity1 :: ('9606', 'Species') :: ['girl', 'boy'] @entity7350 :: ('MESH:D017593', 'Disease') :: ['KLS', 'Kleine-Levin syndrome'] @entity2147 :: ('MESH:D006970', 'Disease') :: ['RH', 'Recurrent hypersomnia'] @entity395 :: ('MESH:D035583', 'Disease') :: ['rare disorder'] @entity2049 :: ('MESH:D002220', 'Chemical') :: ['Carbamazepine'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep architecture', 'sudden sleepiness'] @entity1090 :: ('MESH:D018967', 'Chemical') :: ['risperidone']
@entity2147 :: (MESH:D006970,Disease) :: ['Recurrent hypersomnia']
