PURPOSE: Primary @entity957 of the colon and rectum are extremely rare, with an incidence of less than 1  % of @entity14 . Our aim in this study was to evaluate @entity1 characteristics, treatment strategy, and postoperative follow-up of @entity1 with @entity14 . METHODS: We reviewed our prospectively maintained @entity14 database for all @entity1 who were diagnosed with @entity14 between January 1990 and April 2009. RESULTS: Out of 5149 @entity1 with @entity14 , 11 @entity1 (0.2  %) met the study criteria. Median age at the time of diagnosis was 64. Median BMI was 28  kg/m(2). The @entity5 were localized in the rectum (n   =   8), right colon (n   =   2), and sigmoid colon (n   =   1). The pathologic stages of these @entity5 were I (n   =   1), II (n   =   4), III (n   =   3), and IV (n   =   3). Operations performed were abdominoperineal resection (n   =   4), right colectomy (n   =   2), total colectomy (n   =   1), low anterior resection (n   =   1), local excision (n   =   1), sigmoidectomy (n=1) and end colostomy creation (n   =   1). One @entity1 received intraoperative radiotherapy. Postoperative chemotherapy was given to eight @entity1 , and three @entity1 received postoperative radiation therapy. Median follow-up after diagnosis was 42  months (12-96). Three @entity1 developed recurrence after potentially curative surgery. Five @entity1 died from metastatic disease during follow-up. CONCLUSION: Squamous @entity14 can be detected in any part of the colon, generally presents at a later stage, and is associated with a poor prognosis. Surgery is the mainstay of treatment. Various adjuvant chemoradiation treatments appear not to influence the outcome. Further cases need to be analyzed in order to find more effective treatment regimens.

@entity14 : a rare XXXX with poor prognosis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal squamous cell carcinoma', 'colorectal malignancies', 'colorectal cancer', 'colorectal malignancy']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
