BACKGROUNDS: As for @entity1419 , the most frequent site of failure after curative intent resection is the liver. We identified the risk factors for locoregional recurrence after curative intent resection for @entity1419 . METHODS: Medical records of 115 @entity1 treated with surgical resection alone for @entity1419 from November 2000 to December 2010 were retrospectively reviewed. Locoregional failure was defined as recurrence within 20 mm from resection margin or regional lymph node. Overall survival and locoregional recurrence rates were analyzed using Kaplan-Meier methods, and the prognostic factors were analyzed using Cox proportional hazards model. RESULTS: Median follow-up duration of surviving @entity1 was 61 months (range 8-139). Sixty-six @entity1 had recurrence, and 45 of 66 @entity1 (68 %) had locoregional recurrence. The 5-year overall survival and locoregional control rates were 49.1 and 51.6 %, respectively. >=  T2b disease and R1 resection were associated with locoregional recurrence in multivariate analysis. @entity1 were divided into two groups whether these risk factors exist or not. The 5-year locoregional control rates of low (no risk factor n = 64) and high (1 or 2 risk factors n = 51) risk groups were 62.5 and 34.7 %, respectively (P = 0.001). CONCLUSIONS: After curative intent resection, locoregional control and survival of @entity1 with @entity1419 were far from satisfactory. Further studies are needed to evaluate the potential benefit of adjuvant locoregional treatment such as radiotherapy for @entity1 with high-risk factors (>=  T2b disease or R1 resection).

Locoregional recurrence after curative intent resection for XXXX : implications for adjuvant radiotherapy.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity1419 :: ('MESH:C535533', 'Disease') :: ['intrahepatic cholangiocarcinoma']
@entity1419 :: (MESH:C535533,Disease) :: ['intrahepatic cholangiocarcinoma']
