The olfactory system of several holometabolous insect species undergoes anatomical changes after eclosion of the imago, following those occurring during metamorphosis. In parallel, odor experience and learning performance also evolve with age. Here, we analyze the case of adult @entity238 females. Synaptogenesis in the @entity1315 ( @entity1315 ) starts in late pupa and continues during the first days of adult life, at the same time as the behavioral response to odors matures. Individual olfactory glomeruli ( @entity70201 , @entity70202 , and V) display specific growth patterns between days 1 and 12 of adult life. Experience can modify the olfactory pathway both structurally and functionally as shown by adaptation experiments. The modifications associated with this form of nonassociative learning seem to take place at a critical age. Exposure to @entity32128 at days 2-5 of adult life, but not at 8-11, causes behavioral adaptation as well as structural changes in @entity70202 and V glomeruli. Altered levels in intracellular @entity268 , caused by dunce and rutabaga mutants, do not affect the normal changes in glomerular size, at least at day 6 of development, but they prevent those elicited by experience, establishing a molecular difference between glomerular changes of intrinsic versus environmental origin. Taken together, these data demonstrate an imprinting-like phenomenon in the olfactory pathway of young @entity238 adults, and illustrate its glomerulus-specific dynamics.

Structural and functional changes in the olfactory pathway of adult XXXX take place at a critical age.

@entity268 :: ('CHEBI:17489', 'Chemical') :: ['cAMP'] @entity70201 :: ('47767(Tax:7227)', 'Gene') :: ['DM6'] @entity32128 :: ('MESH:C032175', 'Chemical') :: ['benzaldehyde'] @entity1315 :: ('MESH:D004833', 'Disease') :: ['antennal lobe', 'AL'] @entity70202 :: ('34727(Tax:7227)', 'Gene') :: ['DM2'] @entity238 :: ('7227', 'Species') :: ['Drosophila']
@entity238 :: (7227,Species) :: ['Drosophila']
