BACKGROUND AND AIMS: The self-propelled disposable colonoscope (SPDC) with a 360   view is designed to enhance visualization, minimize risks of perforation and infection transmission, and shorten operator training time associated with conventional colonoscopy (CC). We evaluated SPDC efficacy for cecal intubation and safety. METHODS: Prospective @entity1 presenting for @entity14 screening underwent SPDC immediately followed by CC. Initial @entity1 necessary for SPDC operators to achieve proficiency comprised the training cohort. Subsequent enrolled @entity1 comprised the study cohort. SPDC colonoscopy was performed up to the cecum, where anatomic landmarks were photographed and mucosal suction marks were placed. During SPDC withdrawal, @entity1127 were recorded and similarly marked. On the second pass (by using CC), any potential @entity16 and suction marks from the SPDC as well as @entity1127 were recorded. Main endpoints included SPDC cecal intubation rates, confirmed by anatomic landmarks and residual marks seen on subsequent CC, and frequency and severity of adverse events and @entity16 with SPDC. The secondary endpoint was subjective procedure proficiency, evaluated by the operator based on the training cohort. The tertiary endpoint was documenting pathologies visualized with SPDC. RESULTS: Fifty-six of 58 enrolled subjects completed the study. Proficiency with SPDC was attained after 8 to 10 procedures. Cecal intubation was successful in 98.2% (55/56 subjects; 95% confidence interval [CI], 90.4%-99.9%), including 100% (95% CI, 90.7%-100%) of the study cohort and 94.4% (95% CI, 72.7%-99.9%) of the training cohort. No @entity16 or adverse events were reported. SPDC detected 87.5% of @entity1127 seen in tandem CC, including all @entity1127 larger than 5  mm. CONCLUSIONS: SPDC was highly successful, simple to use, and safe in achieving complete colonoscopy (cecal intubation). (Clinical trial registration number: 0692-12-TLV.).

A novel self-propelled disposable colonoscope is effective for colonoscopy in XXXX (with video).

@entity1 :: ('9606', 'Species') :: ['patients'] @entity16 :: ('MESH:D009422', 'Disease') :: ['mucosal damage'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer']
@entity1 :: (9606,Species) :: ['humans']
