OBJECTIVE: The feasibility and clinical effects of hollow obturator prosthesis for the repair of maxillofacial defect immediately after maxillectomy for @entity5 were assessed. METHODS: Thirteen @entity1 with T3-4aN0M0 maxillary @entity5 were treated by the prostheses immediately after maxillectomy. According to the 3D-CT reconstruction of nasal sinus, the 3D stereoscopic prototype was constructed before the surgery. Simulating surgery with Surgicare 5.0 software and then the prosthesis 3D stereoscopic model was shaped. The prosthesis was made quickly and precisely with @entity11379 resins according to the model and the print mold before surgery, with supplementary tooth at the bottom of prosthesis. In the surgery, the prosthesis was installed instantly after maxillectomy. The @entity1 were followed up at 1, 3 and 6 month after the surgery, respectively. The facial features and the pronunciation clarity were examined and the questionnaires were carried out in the @entity1 , with comparation by paired t-test. The hollow obturator prosthesis would be replaced by permanent prosthesis made of @entity11379 resins at 6 month after the surgery. RESULTS: The hollow obturator prostheses were installed accurately and @entity17323 were repaired immediately after maxillectomy in the 13 @entity1 . Postoperative follow-up showed there were significant differences in eyeball sagging (t = 4.67, P < 0.05), mid-facial region collapse (t = 5.67, P < 0.05), and pronunciation clarity (t = 16.38, P < 0.05) between @entity1 with and without prostheses. Questionnaires showed that all the @entity1 were satisfied with the retention of prostheses, the improvement of appearance, the improvement of the symptom of water choking and speech definition. Six months after the surgery, the hollow obturator prostheses were replaced smoothly by permanent prostheses in 11 of the 13 @entity1 . CONCLUSION: The precise and instant repair of maxillofacial defect by prosthesis after maxillectomy can improve survival quality of @entity1 .

[Rehabilitation by hollow obturator prosthesis immediately after total maxillectomy for XXXX ].

@entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'neoplasm'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity11379 :: ('CHEBI:25218', 'Chemical') :: ['methacrylate'] @entity17323 :: ('MESH:D019767', 'Disease') :: ['maxillofacial defects']
@entity5 :: (MESH:D009369,Disease) :: ['malignant tumor']
