Experimental studies have consistently shown the inhibitory activities of tea extracts on tumorigenesis in multiple model systems. Epidemiological studies, however, have produced inconclusive results in @entity1 . A comprehensive review was conducted to assess the current knowledge on tea consumption and risk of @entity5 in @entity1 . In general, consumption of black tea was not associated with lower risk of @entity5 . High intake of green tea was consistently associated with reduced risk of upper @entity1820 after sufficient control for confounders. Limited data support a protective effect of green tea on lung and hepatocellular @entity105 . Although observational studies do not support a beneficial role of @entity263 risk, phase II clinical trials have demonstrated an inhibitory effect of green tea extract against the progression of prostate pre-malignant lesions. Green tea may exert beneficial effects against mammary @entity105 in premenopausal @entity1 and recurrence of @entity0 . There is no sufficient evidence that supports a protective role of tea intake on the development of @entity5 of the colorectum, pancreas, urinary tract, @entity11 , @entity706 , and @entity1778 . Future prospective observational studies with biomarkers of exposure and phase III clinical trials are required to provide definitive evidence for the hypothesized beneficial effect of tea consumption on @entity5 formation in @entity1 .

Tea and XXXX prevention: epidemiological studies.

@entity1 :: ('9606', 'Species') :: ['women', 'humans'] @entity263 :: ('MESH:D011471', 'Disease') :: ['tea intake on prostate cancer'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'cancer'] @entity11 :: ('MESH:D005910', 'Disease') :: ['glioma'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['leukemia'] @entity1820 :: ('MESH:D005770', 'Disease') :: ['gastrointestinal tract cancers'] @entity105 :: ('MESH:D063646', 'Disease') :: ['carcinogenesis']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
