OBJECTIVES: Several studies have shown increased atherogenic risk factors and biomarkers of @entity32 and @entity731 in association with growth hormone excess. Mean platelet volume ( @entity6688 ) and red blood cell distribution (RDW) are currently gaining interest as new independent cardiovascular risk factors. The aim of this study was to evaluate the effect of disease control on @entity6688 and RDW in @entity2012 @entity1 . MATERIALS AND METHODS: We retrospectively enrolled 36 @entity2012 @entity1 (23 males, 13 females; mean age 41.94    11.55). @entity1 were divided into two groups: disease controlled by surgical treatment alone (group A) or by @entity1943 analog (SSA) therapy (group B). @entity6688 and RDW measurements were evaluated during active and inactive disease periods in the two groups. RESULTS: There were statistically significant increases in @entity6688 and RDW in @entity1 receiving SSA therapy (P = 0.012 and P = 0.020, respectively). The differences in @entity6688 and RDW changes in @entity1 receiving surgical treatment alone were not statistically significant (P=0.364 and P=0.339, respectively). CONCLUSIONS: This is the first report on the evaluated the effect of disease control on @entity6688 and RDW in @entity2012 @entity1 . Our study results showed that @entity6688 and RDW measurements are significantly increased in @entity2012 @entity1 with disease controlled by SSA therapy. Therefore, acromegalic @entity1 treated with SSAs may have increased cardiovascular risk based on an increase in @entity6688 and RDW.

The effect of disease control on mean platelet volume and red blood cell distribution in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity2012 :: ('MESH:D000172', 'Disease') :: ['acromegaly'] @entity1943 :: ('MESH:D013004', 'Chemical') :: ['somatostatin'] @entity6688 :: ('10244', 'Species') :: ['MPV']
@entity2012 :: (MESH:D000172,Disease) :: ['acromegaly']
