UNASSIGNED: This is a retrospective study on the safety and efficacy of gamma knife radiosurgery (GKR) in treating @entity157 ( @entity157 ) with portal vein @entity5 @entity715 (PVTT). @entity1 with confirmed @entity157 and PVTT were allocated into two groups based on the treatments they received (palliative or GKR). A total of 138 @entity1 were included (74 in the palliative group, 64 in GKR group). No significant differences in baseline characteristics existed between the two groups. Treatment-related adverse events (AEs) were recorded and compared between groups. The majority of AEs were mild to moderate and subsided naturally or after medication. There was no AE-induced @entity204 . The influences of baseline characteristics and treatment options on @entity1 ' @entity3012 were analyzed. The median @entity3012 of @entity1 in the palliative and GKR group were 3.0 months (95% CI: 2.719-3.281) and 6.1 months (95% CI: 4.706-7.494) respectively (p = 0.003). Multivariate analysis revealed that GKR treatment, performance status 0-1, @entity1 A, smaller @entity5 diameter and monolobar distribution were significant favorable prognosticators. Subgroup analyses showed @entity3012 benefit of GKR regardless of PVTT location (main or branch of PVTT). In conclusion, GKR is well tolerated in selected @entity157 -PVTT @entity1 and can confer @entity3012 benefit, which needs validation in future prospective studies.

Tolerability and efficacy of gamma knife radiosurgery on @entity157 with portal vein XXXX @entity715 .

@entity1 :: ('9606', 'Species') :: ['Child', 'Patients', 'patients'] @entity3012 :: ('MESH:C567932', 'Disease') :: ['OS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
