PURPOSE: @entity306 is characterized by @entity73 following injury  to the developing brain. Neurogenic lower urinary tract dysfunction is estimated to affect at least a third of @entity1 with @entity306 . However there  are limited data as @entity1 transition to adulthood. We sought to describe the symptoms, sequelae and management of @entity1973 in adults with @entity306 . MATERIALS AND METHODS: We retrospectively reviewed the charts of adult @entity1 with @entity306 between 2011 and 2014. @entity1 with prior bladder reconstruction or catheterization based bladder drainage were excluded from study. @entity306 severity was determined using GMFCS (Gross Motor Function Classification System). A conservative evaluation and treatment paradigm was used. Noninvasive treatments were encouraged. Specifically clean intermittent catheterization, which is often not feasible, is avoided unless urinary retention, @entity3041 or refractory lower urinary tract symptoms develop. RESULTS: There were 121 @entity1 included in final analysis. Median age was 25  and 61 @entity1 (50%) had GMFCS level V. Noninvasive management failed in  28 of 121 @entity1 (23%) as defined by @entity3041 in 9, persistent urinary retention in 10 and refractory lower urinary tract symptoms/ @entity322 in 9. Urethral clean intermittent catheterization was poorly tolerated. Of all @entity1 25% showed evidence of @entity1791 during the study period. Surgical intervention was rare and associated with significant morbidity. CONCLUSIONS: Adults with @entity306 may present with variable signs and symptoms of @entity1973 . Conservative treatment was successful in more than 75% of @entity1 . Clean intermittent catheterization was poorly tolerated in @entity1 in whom conservative treatment failed. Surgical intervention was rarely indicated and it should be reserved for select individuals.

Neurogenic Lower Urinary Tract Dysfunction in Adults with XXXX : Outcomes following a Conservative Management Approach.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients'] @entity322 :: ('MESH:D014549', 'Disease') :: ['incontinence'] @entity73 :: ('MESH:D003072', 'Disease') :: ['motor impairment'] @entity1973 :: ('MESH:D001750', 'Disease') :: ['neurogenic lower urinary tract dysfunction'] @entity3041 :: ('MESH:D006869', 'Disease') :: ['hydronephrosis'] @entity1791 :: ('MESH:D052878', 'Disease') :: ['urolithiasis'] @entity306 :: ('MESH:D002547', 'Disease') :: ['cerebral palsy', 'Cerebral palsy']
@entity306 :: (MESH:D002547,Disease) :: ['Cerebral Palsy']
