@entity79 is a rare @entity5 consisting of thin, wavy fibroblasts set in an abundant matrix of collagen fibers. At times it is difficult to distinguish @entity20392 from other @entity82 , especially low-grade @entity1492 . Fewer than eight cases have been previously reported. We have reviewed the diagnostic and therapeutic findings of eighty additional cases. Six @entity1 had the lesions located in an extremity and two had an @entity75 . The average age of the @entity1 was twenty-five years (range, twelve to fifty-six years) and all of the @entity1 had more than two years of follow-up (range, two to seventeen years). The radiographic findings in all but one @entity1 were of a purely lytic, honeycombed lesion that often widened the bone, and was metaphyseal in long bones. The @entity5 replaced the medullary cavity with a grayish-white, rubbery to firm tissue that was often, but not always, contained by a rim of periosteal reactive bone. Histologically, the features were: (1) prominent loose bundles of fibrous tissue composed of slim, spindle-shaped fibroblasts with wavy, elongated nuclei; (2) variable amounts of bands of collagen fibers; and (3) absence of mitoses or atypical cells. Areas of metaplastic bone were found only around sites, of pathological @entity174 . The biology of @entity20392 is different from that of other benign @entity82 in that the lesion is very destructive locally and often recurs after incomplete excision. It is also distinguished from low-grade malignant lesions (for example, @entity1492 ) in that metastases have never been reported. In our series an intralesional excision was initially performed in six of the eight @entity1 and a marginal resection, in two. There were four recurrences, treated by a marginal resection in two @entity1 and repeat curettage in one. The recurrence in the fourth @entity1 required an amputation above the knee after two additional intralesional procedures had been unsuccessful. Wide or marginal resection appears to be the treatment of choice when the lesion is located in a site that can be resected without significant loss of function. In other areas, an attempt at curettage, instillation of @entity3971 , and bone-grafting seems to be warranted, resorting to more radical procedures only if this fails to control @entity66 .

XXXX . A report of eight cases and review of the literature.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrous lesions'] @entity66 :: ('MESH:D004194', 'Disease') :: ['local disease'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'benign tumor'] @entity20392 :: ('MESH:D018220', 'Disease') :: ['desmoplastic fibroma'] @entity75 :: ('MESH:D001927', 'Disease') :: ['axial lesion'] @entity1492 :: ('MESH:D005354', 'Disease') :: ['fibrosarcomas', 'fibrosarcoma'] @entity79 :: ('MESH:D001847', 'Disease') :: ['Desmoplastic fibroma of bone'] @entity3971 :: ('MESH:D019800', 'Chemical') :: ['phenol']
@entity79 :: (MESH:D001847,Disease) :: ['Desmoplastic fibroma of bone']
