BACKGROUND: There is a significant worldwide variation in practice regarding the criteria for operative intervention and overall management in @entity1 with locally recurrent @entity5 (LRRC). A survival benefit has been described for @entity1 with clear resection margins in @entity1 undergoing surgery for LRRC which is seen as an important surgical quality indicator. METHODS: A prospective French national database was established in 2008 which recorded procedures undertaken for locally recurrent @entity5 (LRRC). Overall and Disease-Free Survival (OS, DFS) were assessed retrospectively. We report the variability and the heterogeneity of LRRC management in France as well as 5-year oncological outcomes. RESULTS: In this national report, 104 questionnaires were completed at 29 French surgical centres with a high variability of cases-loaded. @entity1 had preoperative treatment in 86% of cases. Surgical procedures included APER (36%), @entity8800 (25%), Hartmann's procedure (21%) and pelvic exenterations (15.5%). Four @entity1 had a low sacrectomy (S4/S5). There were no postoperative deaths and overall morbidity was 41%. R0 was achieved in 60%, R1 and R2 in 29% and 11%, respectively. R0 resection resulted in a 5-year OS of 35% compared to 12% and 0% for respectively R1 and R2 (OR  =  2.04; 95% CI: 1.4-2.98; p  <  0.001). OS was similar between R2 and non-resected @entity1 (OR  =  1.47; 95% CI: 0.58-3.76; p  =  0.418). CONCLUSIONS: Our data is in accordance with the literature except the rate of extended resection procedures. This underlines the selective character of operative indications for LRRC in France as well as the care variability and the absence of optimal clinical pathway regarding these @entity1 .

French current management and oncological results of  locally recurrent XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity8800 :: ('5792', 'Gene') :: ['LAR'] @entity5 :: ('MESH:D009369', 'Disease') :: ['rectal cancer']
@entity5 :: (MESH:D009369,Disease) :: ['rectal cancer']
