PURPOSE: Transplant nephrectomy has been considered a hazardous procedure throughout transplantation history. Better surgical techniques and clinical treatment of @entity1 have improved the results of this surgery in the last decades. We report the surgical complications of nephrectomy of early and late failed kidneys performed at a referral center. MATERIALS AND METHODS: The charts of 70 consecutive @entity1 who underwent graft nephrectomy between May 1994 and April 2002 were reviewed regarding surgical complications. @entity1 were divided into 2 groups according to the timing of graft removal. Early nephrectomy group 1 included 23 procedures performed in the first 60 days after transplantation and late nephrectomy group 2 included 47 performed after that interval. Groups were compared concerning outcome, @entity190 and amount of blood transfused in the perioperative period, and the incidence of surgical complications according to the surgical technique, immunosuppressive regimen and timing of surgery. RESULTS: Mean @entity190 was 434 ml (range 20 to 3,000) in group 1 and 546 (range 60 to 2,200) in group 2 (p = 0.02). Nine group 1 @entity1 (39.1%) and 22 in group 2 (46.8%) received blood transfusion in the perioperative period (p = 0.62). The mean amount of blood transfused was 516.7 ml in group 1 and 436.3 ml in group 2 (p = 0.36). Four and 2 minor surgical complications occurred in groups 1 and 2 (17.4% and 4.3%, respectively, p = 0.09). Seven major complications were noted in group 2 (14.9%), while there were none in group 1 (p = 0.05). Three complications (25%) occurred in @entity1 who received antirejection globulins or @entity1667 and 1 (9.1%) developed when these agents were not administered (p = 0.33). The incidence of surgical complications after intracapsular and extracapsular nephrectomy was 20% and 17.6%, respectively (p = 0.58). Mean @entity190 and the mean amount of blood transfused was 638 and 525 ml for intracapsular nephrectomy and 383 and 350 ml for extracapsular nephrectomy, respectively, respectively. @entity532 occurred in 3 @entity1 who received @entity618 (23.1%) and in 6 (17.6%) who did not received this drug (p = 0.48). CONCLUSIONS: @entity190 and surgical complication rates were higher in late failed graft nephrectomies. @entity532 in intracapsular vs extracapsular nephrectomies were similar but @entity190 and transfusions were higher for intracapsular nephrectomy. Acute rejection treatment, or prophylaxis with @entity1667 or globulins increased the incidence of surgical complications.

XXXX of graft nephrectomy in the modern transplant era.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1667 :: ('MESH:D008775', 'Chemical') :: ['methylprednisolone'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss', 'Blood loss'] @entity532 :: ('MESH:D003925', 'Disease') :: ['Surgical complications'] @entity618 :: ('MESH:C063008', 'Chemical') :: ['mycophenolate mofetil']
@entity532 :: (MESH:D003925,Disease) :: ['Surgical complications']
