Little is known about the long-term outcome of @entity1 with @entity1374 , an extrathyroidal manifestation of @entity2743 . Also, it is not known to what degree treatment promotes remission of the lesions. The present report supplies information on the natural course of mild, untreated and severe, treated @entity1374 . In this study, we report on the outcomes of 178 @entity1 seen at our institution between January 1969 and November 1995 with @entity1374 who were followed up for an average of 7.9 yr. Nonpitting @entity4 was the most prevalent form of @entity3431 (43.3%), and the pretibial area was the region most commonly involved (99.4%). The majority of @entity1 with @entity3431 had @entity6875 (97.0%). Topical corticosteroids were the most commonly used treatment (53.9%). @entity1 with milder forms of @entity3431 (40.4%) did not receive any therapy for @entity3431 . Twenty-six percent of the @entity1 experienced complete remission, 24.2% had moderate improvement (partial remission), and 50.0% had no or minimal improvement of their @entity3431 at last follow-up. @entity1 who did not receive therapy experienced a significantly (P = 0.03) higher rate of complete remission (34.7%) than those who received local therapy (18.7%), although the combined complete and partial remission rates were not significantly different for the treated and untreated groups (P = 0.3). However, the treated and untreated groups were not comparable because our practice is to use therapy for more extensive and severe cases. All five cases of @entity28802 were in the treatment group and were less likely to have remission because of the severity of their @entity272 . @entity1 receiving treatment were more likely to have dermatologic consultation and histologic diagnosis (P < 0.001). The beneficial effect of topical corticosteroid therapy on long-term remission rates remains to be determined.

XXXX (pretibial myxedema): long-term outcome.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2743 :: ('MESH:D006111', 'Disease') :: ["Graves' disease"] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity3431 :: ('MESH:C536920', 'Disease') :: ['dermopathy'] @entity28802 :: ('MESH:D004604', 'Disease') :: ['elephantiasis'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin condition'] @entity6875 :: ('MESH:D049970', 'Disease') :: ['ophthalmopathy'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroid dermopathy']
@entity2743 :: (MESH:D006111,Disease) :: ['Dermopathy of Graves' disease']
