BACKGROUND: Muscle @entity1674 (TG) are known to be a source of energy during submaximal exercise. OBJECTIVE: The aim of this study was to assess whether an index of muscle fat content is related to maximal fat oxidation rate (FATOXmax) in 58 @entity28 @entity1 (mean age 46.0+/-0.8 (s.e.) y, body weight 96.4+/-1.4 kg, percentage fat: 31.9+/-0.5%) [corrected]. DESIGN: FATOXmax was defined as the highest value of fat oxidation rate, measured by indirect calorimetry, while walking on a treadmill (4.3 km/h) at three different slopes: 0% (40+/-1% of VO2max), 3% (47+/-1% of VO2max) and 6% (58+/-1% of VO2max). @entity1386 ( @entity1386 ) and fat mass (FM) were measured with the underwater technique and scans were obtained by computed tomography (CT) at the mid thigh level to assess areas of adipose tissue within skeletal muscle, ie deep adipose tissue (DAT), @entity1386 ( @entity1386 ), skeletal muscle (M) and low attenuation skeletal muscle (LAM, range of attenuation values: 0-34 Hounsfield units). LAM and DAT were used as indices of skeletal muscle fat content. RESULTS: FATOXmax, adjusted for age, was correlated with @entity1386 (r=0.26, P<0.05), LAM (r=0.29, P<0.05), abdominal visceral adipose tissue (r=0.30, P<0.05) and plasma free @entity844 (FFA) levels (r=0.33, P<0.05) but not with @entity1386 (r=0.03) and DAT (r=0.21) [corrected]. In a stepwise linear multiple regression, plasma FFA, age and LAM significantly predicted FATOXmax (r2=0.27). Each independent variable explained about 9% of the FATOXmax variance. CONCLUSION: LAM makes a significant but weak contribution to the modulation of fat oxidation during submaximal exercise in @entity28 @entity1 .

Skeletal muscle low attenuation area and maximal fat oxidation rate during submaximal exercise in XXXX individuals.

@entity1 :: ('9606', 'Species') :: ['men'] @entity844 :: ('CHEBI:35366', 'Chemical') :: ['fatty acid'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triacylglycerols'] @entity1386 :: ('MESH:D018205', 'Disease') :: ['subcutaneous adipose tissue', 'SAT', 'FFM', 'Fat-free mass']
@entity28 :: (MESH:D009765,Disease) :: ['male obese']
