Increases in arterial wall viscosity and @entity121 ( @entity121 ) were found in @entity101 @entity1 . Because smooth muscle cells are responsible for the viscous behavior of the arterial wall and they are involved in the process of thickening of the intima-media complex, this study evaluates the relationship between carotid thickness and wall viscosity. The simultaneous and noninvasive assessment of the intima-media complex and arterial diameter waveform was performed using high-resolution ultrasonography. This technique was contrasted against sonomicrometry in @entity742 , showing that the waveforms obtained by both methods were similar. The common carotid arteries of 11 normotensive subjects (NTA) and 11 @entity1 with mild to moderate @entity101 ( @entity27634 ) were measured noninvasively by using tonometry and an automatic densitometric analysis of B-mode images to obtain @entity121 and instantaneous pressure and diameter loops. A viscoelastic model was used to derive the wall viscosity index ( @entity2231 ) using the hysteresis loop elimination criteria. In NTA, @entity2231 was 2.73+/-1.66 (mm Hg x s/mm) and @entity121 was 0.58+/-0.08 (mm), whereas in @entity27634 , @entity2231 was 5.91+/-2.34 (P<.025) and @entity121 was 0.70+/-0.12 (P<.025), respectively. When all data of @entity2231 versus @entity121 of NTA and @entity27634 were pooled in a linear regression analysis, a correlation coefficient of r=.71 (P<.05) was obtained. Partial correlation between @entity2231 and @entity121 holding constant pressure was r=.59 (P<.05). In conclusion, wall viscosity increase was associated with a higher @entity121 even maintaining blood pressure fixed, suggesting that the intima-media thickening might be related to smooth muscle alterations manifested as an increase in viscous behavior.

Carotid wall viscosity increase is related to intima-media thickening in XXXX @entity1 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['essential hypertension', 'hypertensive'] @entity742 :: ('9940', 'Species') :: ['sheep'] @entity2231 :: ('1909', 'Gene') :: ['eta'] @entity121 :: ('MESH:D009135', 'Disease') :: ['IMT', 'intima-media thickness'] @entity27634 :: ('283902', 'Gene') :: ['HTA']
@entity101 :: (MESH:D006973,Disease) :: ['hypertensive']
