OBJECTIVE: The aim was to evaluate the effect of a @entity1216 -containing brush-on gel when used as supplement to oral hygiene instructions and mechanical debridement, on @entity33 in adults. MATERIALS AND METHODS: The study group consisted of 38 adults (48-87 years.) with @entity33 that were consecutively enrolled in three private clinics after informed consent. The study employed a double-blind controlled design with two parallel arms. After baseline registrations, oral hygiene reinforcement and mechanical debridement, the @entity1 were randomly allocated to either a test group with once daily tooth brushing with an oral care brush-on gel containing 0.2% @entity5164 (Cervitec Gel) or a control gel group. The duration of the intervention was 12 weeks. The primary outcome was @entity548 on probing (BOP) and secondary endpoints were local plaque score (LPS) and @entity5951 ( @entity5951 ). RESULTS: The groups were balanced at baseline. The daily use of the @entity1216 -containing gel resulted in reduced BOP after 4 and 12 weeks compared with the control group (P < 0.05). The @entity5951 was significantly reduced (P < 0.05) after 12 weeks compared to baseline in the test group, but not in the control group. No side effects or adverse events were reported. CONCLUSION: The present findings indicated moderate but significant improvements of clinical parameters when mechanical debridement was combined with a self-applied oral care brush-on gel for the management of @entity33 .

Effect of a @entity1216 -containing brush-on gel on XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1216 :: ('MESH:D002710', 'Chemical') :: ['chlorhexidine'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity33 :: ('MESH:D052016', 'Disease') :: ['peri-implant mucositis'] @entity5951 :: ('MESH:D005888', 'Disease') :: ['PPD', 'pocket probing depth'] @entity5164 :: ('MESH:C010882', 'Chemical') :: ['chlorhexidine digluconate']
@entity33 :: (MESH:D052016,Disease) :: ['peri-implant mucositis']
