UNASSIGNED: @entity4503 is associated with @entity384 . Timing of follow-up and surgery is challenging. Hence, there is an unmet clinical need for additional risk stratification. It is unclear whether valve morphology is associated with dilatation rates. Therefore, the objective of this study was to examine the association between clinical and echocardiographic determinants (including valve morphology) and aortic dimension and the progression rate of dilatation.Aortic dimensions were assessed on serial echocardiographic images between 1999 and 2014 in a population of 392 @entity1 with BAVs in a tertiary care center in the Netherlands. Analyses using mixed linear models were performed.Mean age of @entity1 was 48  17 years and 69% were male. BAV morphology was associated with aortic dimensions, as well as age, sex, BSA, and @entity340 . Tubular ascending aorta, sinus of Valsalva, and sinotubular junction showed a dilatation rate of 0.32, 0.18, and 0.06mm/year, respectively. Dilatation rate was not associated with valve morphology.In the present study, there is no association between BAV morphology and @entity384 rates. Therefore, morphology is of limited use in prediction of aortic growth. Discovering fast progressors remains challenging.

Clinical and echocardiographic determinants in bicuspid XXXX : Results from a longitudinal observational study.

@entity4503 :: ('MESH:C562388', 'Disease') :: ['Bicuspid aortic valve (BAV) disease'] @entity384 :: ('MESH:D002311', 'Disease') :: ['aortic dilatation'] @entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity340 :: ('MESH:D006349', 'Disease') :: ['valvular dysfunction']
@entity384 :: (MESH:D002311,Disease) :: ['aortic dilatation']
