BACKGROUND: Hepatic resection for @entity157 (HCCs) involving both lobes of the liver is rarely recommended because of high operative risks and low radicality. Thus the justification of hepatic resection for bilobar multicentric @entity157 remains undefined. METHODS: Two hundred eleven @entity1 with @entity157 , who underwent curative hepatic resection, were studied retrospectively. The @entity1 were divided into two groups. Group A consisted of 39 @entity1 with bilobar (both sides of Cantlie's line) multicentric HCCs. Group B consisted of 172 @entity1 with @entity157 with solitary or unilobar lesions. The backgrounds and resectional results of @entity1 in groups A and B were compared. RESULTS: @entity1 in group A usually required multiple separate liver resections and a longer operative time. However, the operative @entity190 , amount of blood transfused, and operative morbidity and mortality rates were not significantly different. @entity1 in group A showed higher incidences of associated satellite nodules, microscopic vascular invasion, and a lack of capsules. The 6-year disease-free and actuarial survival rates of @entity1 in groups A and B were 30.5% and 41.8% (p = 0.17) and 42.9% and 51.4% (p = 0.12), respectively. For @entity1 in group A the presence of satellite nodules in any resected @entity5 was the only independent unfavorable feature that influenced the actuarial survival rate after multivariate analysis. CONCLUSIONS: Liver resection is justified for bilobar multicentric HCCs in selected @entity1 , if the @entity5 can be totally resected. Postoperative adjuvant therapies should be considered when satellite nodules are present in any resected @entity5 .

Hepatic resection for bilobar XXXX : is it justified?

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'multiple hepatocellular carcinomas'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors']
@entity157 :: (MESH:D006528,Disease) :: ['multicentric hepatocellular carcinoma']
