INTRODUCTION: Surgical release is the most effective therapy for the symptoms of @entity923 ( @entity923 ). It is widely considered that surgery may be ineffective in 'extreme' cases (those with @entity2057 and no sensory and motor response of the median nerve). OBJECTIVE: To report clinical and electrophysiological outcome of 10 subjects with 'extreme' @entity923 surgically treated. METHODS: Ten hands belonging to 10 @entity1 (9 @entity1 and one @entity1 , mean age 65 years) underwent surgical release by the mini-incision of the palm technique. All showed @entity194 and absence of motor and sensory responses of the median nerve. The protocol consisted of clinical and electrophysiological evaluation, with the @entity1 completing the self-administered Boston questionnaire (BQ) before the operation and one and 6 months after it. RESULTS: After surgical release, all @entity1 reported an absence of @entity158 and disappearance or @entity353 . Six months after the operation, motor and sensory responses of the median nerve returned in 8 and 5 hands, respectively. The BQ showed a significant improvement in symptom and functional scores, although @entity2057 remained unchanged. No correlation was found between the degree of clinical and electrical improvement and the age of the @entity1 . CONCLUSION: It is possible to obtain good clinical and electrophysiological results even in extreme cases of @entity923 .

Clinical and neurophysiological outcome of surgery in extreme XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'man'] @entity353 :: ('MESH:D015431', 'Disease') :: ['reduction of paraesthesia'] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy of thenar eminence'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity923 :: ('MESH:D002349', 'Disease') :: ['CTS', 'carpal tunnel syndrome'] @entity2057 :: ('MESH:D009133', 'Disease') :: ['atrophy of the thenar eminence muscles', 'muscle atrophy']
@entity923 :: (MESH:D002349,Disease) :: ['carpal tunnel syndrome']
