HISTORY AND CLINICAL FINDINGS: A 61-year-old @entity1 in poor general health was admitted to hospital because of progressive diarrheo, @entity11634 , @entity1295 and @entity353 . The @entity1 had a history of @entity66 with poor dietary compliance over many years. Hence, the present clinical deterioration was unresponsive to a gluten-free diet. INVESTIGATIONS: Laboratory results showed signs of @entity32 and malabsorption. The endoscopy of the duodenum revealed a flattened @entity33 , as is typical for @entity66 . Enteroscopy revealed many small jejunal lesions. Histological examination of mucosa showed typical signs of @entity66 without definite signs of @entity706 . Immunhistochemical analysis showed atypical intraepithelial T-cells, while the molecular biological study revealed a monoclonal T-cell clone, both supporting the diagnosis of an @entity7017 associated @entity784 (EATCL). DIAGNOSIS AND THERAPY: The @entity1 was enrolled in a study on @entity1893 and accordingly received 6 courses of @entity3726 -chemotherapy. Clinical and histological improvement has lasted for over a year. CONCLUSION: @entity1 with @entity66 unresponsive to a gluten-free diet or with a deteriorating clinical condition may have an @entity7017 -associated @entity784 . This can manifest itself in the form of an @entity1066 . In the early stages of disease, immunhistochemical and molecularbiological analyses may lead to the correct diagnosis.

[Enteropathy-associated XXXX . Manifestation as diet-refractory @entity66 and ulcerating jejunitis].

@entity1 :: ('9606', 'Species') :: ['Patients', 'woman', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity66 :: ('MESH:D004194', 'Disease') :: ['coeliac disease'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma'] @entity3726 :: ('1649', 'Gene') :: ['CHOP'] @entity33 :: ('MESH:D052016', 'Disease') :: ['mucosal architecture'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity7017 :: ('MESH:C538273', 'Disease') :: ['enteropathy'] @entity784 :: ('MESH:D016399', 'Disease') :: ['T-cell lymphoma'] @entity11634 :: ('MESH:D005414', 'Disease') :: ['flatulence'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcerative jejunitis'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['intestinal non-Hodgkin lymphomas']
@entity784 :: (MESH:D016399,Disease) :: ['T-cell lymphoma']
