The aim of this study was to assess the relationship between morbidity from @entity173 and that from other @entity3604 by age and sex based on the population of Sweden. @entity3604 were designated as those associated with low bone mineral density (BMD) and those that increased in incidence with age after the age of 50 years. Severity of @entity174 was weighted according to their morbidity using utility values based on those derived by the National @entity170 Foundation. Morbidity from @entity174 other than @entity173 was converted to @entity173 equivalents according to their disutility weights. Excess morbidity was 3.34 and 4.75 in @entity1 and @entity1 at the age of 50 years, i.e. the morbidity associated with @entity3604 was 3-5 times that accounted for by @entity173 . Excess morbidity decreased with age to approximately 1.25 between the ages of 85 and 89 years. On the assumption that the age- and sex-specific pattern of @entity174 due to @entity170 is similar in different communities, the computation of excess morbidity can be utilized to determine the total morbidity from @entity3604 from knowledge of @entity173 rates alone. Such data can be used to weight probabilities of @entity173 in different countries in order to take into account the morbidity from @entity174 other than @entity173 , and to modify intervention thresholds based on @entity173 risk alone. If, for example, a 10-year probability of @entity173 of 10% was considered an intervention threshold, this would be exceeded in @entity1 with @entity170 aged 65 years and more, but when weighted for other @entity3604 would be exceeded in all @entity1 (and @entity1 ) with @entity170 .

The burden of XXXX : a method for setting intervention thresholds.

@entity3604 :: ('MESH:D058866', 'Disease') :: ['Osteoporotic fractures', 'osteoporotic fractures'] @entity1 :: ('9606', 'Species') :: ['women', 'men'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures'] @entity170 :: ('MESH:D010024', 'Disease') :: ['Osteoporosis', 'osteoporosis'] @entity173 :: ('MESH:D006620', 'Disease') :: ['hip fracture']
@entity3604 :: (MESH:D058866,Disease) :: ['osteoporotic fractures']
