OBJECTIVE: @entity5815 ( @entity5815 ) is characterised by persistent @entity1295 , exhaustion, and several physical complaints. Research has shown cognitive behavioural therapy (CBT) and graded exercise training (GET) to be the most effective treatments. In a first step we aimed to assess the efficacy of heart rate variability biofeedback therapy (HRV-BF) as a treatment method comprising cognitive and behavioural strategies and GET in the pilot trial. In a second step we aimed to compare both interventions with regard to specific parameters. METHODS: The study was conducted in an outpatient treatment setting. A total of 28 @entity1 with @entity5815 (50.3  9.3years) were randomly assigned to receive either eight sessions of HRV-BF or GET. The primary outcome was @entity1295 severity. Secondary outcomes were mental and physical quality of life and @entity308 . Data were collected before and after the intervention as well as at a 5-month follow-up. RESULTS: General @entity1295 improved significantly after both HRV-BF and GET. Specific cognitive components of @entity1295 , mental quality of life, and @entity308 improved significantly after HRV-BF only. Physical quality of life improved significantly after GET. There were significant differences between groups regarding mental quality of life and @entity308 favouring HRV-BF. CONCLUSION: Both interventions reduce @entity1295 . HRV-BF seems to have additional effects on components of mental health, including @entity308 , whereas GET seems to emphasise components of physical health. These data offer implications for further research on combining HRV-BF and GET in @entity1 with @entity5815 . TRIAL REGISTRATION: The described trial has been registered at the International Clinical Trials Registry Platform following the number DRKS00005445.

Heart rate variability biofeedback therapy and graded exercise training in management of XXXX : An exploratory pilot study.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity5815 :: ('MESH:D015673', 'Disease') :: ['Chronic fatigue syndrome', 'CFS']
@entity5815 :: (MESH:D015673,Disease) :: ['chronic fatigue syndrome']
