PURPOSE: Several studies have reported upgrading of @entity1 with Gleason score (GS) at the time of prostate biopsy to GS following radical prostatectomy (RP). We reviewed the predictive accuracy of extended 14-core prostate biopsies, in terms of GS and @entity5 location in @entity1 with @entity263 ( @entity263 ) treated by RP. METHODS: We retrospectively reviewed 163 @entity1 who underwent RP for clinically localized @entity263 . Preoperatively, all @entity1 underwent a transrectal ultrasound-guided biopsy of the prostate (TRUSBP) with 14-core scheme for suspected @entity263 . According to GS, @entity1 were categorized as low ( @entity68971 -6), moderate (GS 7), and high (GS 8-10). A comparison between GS and @entity5 laterality of the needle biopsy and RP specimens was carried out. RESULTS: Bioptic GS was low ( <= 6) in 55.9%, moderate (7) in 34.9%, and high (>= 8) in 9.2% of the @entity1 . Pathological GS was 40.5, 46.6, and 12.9%, respectively. Of the 66 @entity1 with @entity258 by RP, 41 (62.1%) were in agreement with TRUSBP, whereas 25 (37.9%) were underestimated by TRUSBP. Of the 76 @entity1 with moderate GS by RP, 47 were in agreement with TRUSBP (61.8%), and 4 were underestimated by TRUSBP (5.3%). In the assessment of @entity5 laterality, TRUSBP falsely showed 51 cases as @entity5 , whereas RP diagnosed that both sides had @entity263 (p<0.001). CONCLUSION: These data are in line with those of the literature, although the group of @entity5 remained the same only in 40.5% of the cases. Therefore, we conclude that this type of biopsy (14-core TRUSBP) should not be used alone to guide therapy in @entity263 .

Can transrectal ultrasound-guided biopsy of the prostate with extended 14-core scheme improve the predictive accuracy of XXXX treatment?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer', 'PCa'] @entity68971 :: ('8228', 'Gene') :: ['GS 2'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'low-risk tumors', 'unilateral tumors'] @entity258 :: ('MESH:D009800', 'Disease') :: ['low GS']
@entity263 :: (MESH:D011471,Disease) :: ['Gleason score and tumor site in prostate cancer']
