@entity674 ( @entity674 ) are a group of @entity5 arising from mesenchymal stem cells of the gastrointestinal tract. The prognosis of metastatic or recurrent @entity674 is poor, because these @entity5 resist chemotherapy and radiotherapy. We report a @entity1 with recurrent @entity677 who underwent molecularly targeted therapy with @entity2213 , a novel oral @entity669 kinase inhibitor. A 50-year-old @entity1 presented with a huge intra-abdominal mass. The @entity1 had a history of gastrectomy for @entity677 and hepatectomy for its metastases. She also underwent surgery for resection of peritoneal metastases 9 months before. The abdominal mass was 26 x 17 x 12 cm in size, as determined by magnetic resonance imaging, and was diagnosed as a peritoneal relapse of @entity677 . Treatment with 400 mg of @entity2213 daily was started. After 1 week of treatment with @entity2213 , reduction of the @entity5 began to be recognized on palpation. Computed tomographic scanning on day 28 revealed that the @entity5 had liquefactively regressed and had reduced in size by 66%. The major side effect was leg @entity4 , which was easily manageable with @entity1483 . The @entity1 has been receiving @entity2213 treatment in our outpatient clinic, and the @entity5 regression has continued for 9 months. @entity2213 shows promise as a safe and effective drug for the treatment of @entity1 with recurrent @entity674 .

A successful case of oral molecularly targeted therapy with XXXX for peritoneal metastasis of a @entity674 .

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'patient'] @entity677 :: ('MESH:C564650', 'Disease') :: ['GIST'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'abdominal tumor', 'neoplasms', 'tumors'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity1483 :: ('MESH:D005665', 'Chemical') :: ['furosemide'] @entity674 :: ('MESH:D046152', 'Disease') :: ['GISTs', 'Gastrointestinal stromal tumors'] @entity669 :: ('CHEBI:18186', 'Chemical') :: ['tyrosine'] @entity2213 :: ('MESH:C097613', 'Chemical') :: ['imatinib', 'Imatinib']
@entity2213 :: (MESH:C097613,Chemical) :: ['imatinib']
