BACKGROUND: The incidence of @entity420 is increasing. The choice of surgical strategy for AEG type II of Siewert classification is the subjects of controversial discussion. The aim of our retrospective study is to analyse the surgical results in 12 years. MATERIAL AND METHODS: Since 1990 to 2002, 111 @entity1 underwent resection for @entity420 at III Division of General Surgery, University of Turin. Twenty-five @entity1 had AEG type I, 39 had type II and 47 type III. Transthoracic or transhiatal oesophagectomy with resection of the proximal stomach were performed in 55 cases and extended total gastrectomy with transthoracic or transhiatal oesophagectomy in 56. RESULTS: The morbidity and mortality rates are 17% and 5.4%. The 5 years survival rate is poor (35%) for all Siewert type. Survival is significantly associated with stage and the presence of lymph node @entity3 , but not correlated with Siewert classification and surgical approach. Also in the AEG II the survival is not modified by the surgical approach. CONCLUSION: In @entity1 with AEG I the therapy of choice is a radical transthoracic or transhiatal oesophagectomy with resection of the proximal stomach. For type III extended total gastrectomy with transthoracic or transhiatal oesophagectomy is the procedure of choice. The superiority of the thoracoabdominal approach is therefore evident in terms of oncologic radicality. Survival is similar in AEG type II @entity1 for both operations. A oesophagectomy with proximal gastric resection should be adopted for these @entity5 as the standard procedure in the majority of cases.

[ XXXX : surgical strategies compared].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma of the cardia'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity420 :: (MESH:D000230,Disease) :: ['Adenocarcinoma of the cardia']
