OBJECTIVE: A substantial number of @entity370 @entity1 report apparently non-specific symptoms such as @entity158 , for which no organic substrate has yet been found. Recently we observed symptoms suggestive of @entity16 in a group of @entity370 @entity1 . The aim of the present study was to verify this observation using various electrophysiological tests. METHODS: In 74 @entity370 @entity1 complaining of symptoms suggestive of @entity16 , thresholds for warm ( @entity3297 ) and cold sensation (CS) as well as for @entity158 were determined at the thenar eminence and the foot dorsum. Furthermore, sympathetic skin responses (SSR), nerve conduction studies and concentric needle electromyography were performed. In 31 @entity1 , cardiovascular autonomic testing was carried out. RESULTS: Thermal threshold testing (TTT) revealed abnormalities in 51 of the 74 @entity1 . Abnormalities showed an asymmetrical distribution. @entity3297 was affected more often than CS and feet more often than hands. Nerve conduction studies in the legs showed slightly abnormal results in 6 @entity1 ; all of these had abnormal TTT results. The SSR was absent at the foot in 7 @entity1 . Cardiovascular autonomic testing was abnormal in only a single @entity1 . CONCLUSIONS: In a subgroup of @entity370 @entity1 we found TTT abnormalities suggestive of @entity16 . SSR and cardiovascular autonomic testing appeared to be of little diagnostic value. @entity16 may be the cause of a number of hitherto unexplained symptoms in @entity370 .

Abnormal warm and cold sensation thresholds suggestive of @entity16 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity16 :: ('MESH:D009422', 'Disease') :: ['small-fibre neuropathy', 'Small-fibre neuropathy'] @entity3297 :: ('MESH:D018980', 'Disease') :: ['WS'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'heat pain'] @entity370 :: ('MESH:D012507', 'Disease') :: ['sarcoidosis']
@entity370 :: (MESH:D012507,Disease) :: ['sarcoidosis']
