UNASSIGNED: @entity15 ( @entity15 ) is a chronic @entity6220 characterized by @entity62 , @entity17 and @entity179 . Although @entity73 is a common manifestation, it may go unnoticed in recently-diagnosed @entity1 . Prior studies suggest @entity15 @entity1 develop compensatory mechanisms potentially involving enhanced performance monitoring. Here we assessed the performance monitoring system in early-stage @entity15 @entity1 using the error-related negativity (ERN), an event-related brain potential (ERP) observed following behavioral errors. Twenty-seven early-stage @entity15 @entity1 and 31 controls were neuropsychologically assessed. Electroencephalography recordings were obtained while @entity1 performed: a) a stop task and b) an auditory oddball task. Behavior and ERP measures were assessed. No differences in performance were found between groups in most neuropsychological tests or in behavior or ERP components in the auditory oddball task. However, the amplitude of the ERN associated with stop errors in the stop task was significantly higher in @entity1 . ERN amplitude correlated positively with scores on the Expanded Disability Status Scale and the @entity15 Severity Score, and negatively with the time since last relapse. @entity1 showed higher neuronal recruitment in tasks involving performance monitoring. Results suggest the development of compensatory brain mechanisms in early-stage @entity15 and reflect the sensitivity of the ERN to detect these changes.

Neurophysiological Evidence of Compensatory Brain Mechanisms in Early-Stage XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'Patients', 'patients'] @entity6220 :: ('MESH:D020279', 'Disease') :: ['central nervous system disorder'] @entity17 :: ('MESH:D003711', 'Disease') :: ['demyelination'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive dysfunction'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegeneration'] @entity62 :: ('MESH:D056784', 'Disease') :: ['white matter inflammation'] @entity15 :: ('MESH:D009103', 'Disease') :: ['Multiple sclerosis', 'MS', 'Multiple Sclerosis']
@entity15 :: (MESH:D009103,Disease) :: ['Multiple Sclerosis']
