Elevations of phospholipid and @entity2922 concentrations in the blood are regarded as the vital reactions in asphyxial deaths, which leave few or no morphological signs in the body. These vital reactions were tested here, under strict experimental conditions, employing rapid @entity1763 . @entity35 anaesthetized with barbiturate were strangled with a rope 2 mm thick tightened with a force of 29.4 N (3 kp). The main surfactant components, @entity2434 and @entity3633 , were measured in serum and lung samples, and @entity2661 in the serum. The lungs were also investigated histologically. The serum phospholipid concentration in the strangulated @entity35 was 1.36 +/- 0.32 g/l, versus 1.04 +/- 0.17 g/l in the controls (barbiturate intoxication), P < 0.001, but no change in their content was observed in the lungs (26.21 +/- 4.04 mg/g vs. 25.15 +/- 3.64 mg/g dry weight). Histologically, focal @entity2415 and tiny @entity548 were seen in the lungs of both groups with similar frequency. Mean serum @entity1063 (NA) and @entity1425 (A) concentrations were significantly higher in the strangulation group (NA = 5.4 +/- 2.6 ng/ml vs. 2.8 +/- 0.1 ng/ml, P < 0.001 and A = 6.0 +/- 3.4 ng/ml vs. 3.8 +/- 3.0 ng/ml, P < 0.05). The results support the notion that phospholipid and @entity2922 concentrations are increased in the blood upon suffocation and could thus be taken as indicators of @entity519 . Further investigations into postmortem phospholipid change or stability are needed. There are reports that phospholipid concentration remain quite stable for two days post mortem, whereas @entity2922 concentrations tend to rise quite soon after death.

Pulmonary and serum surfactant phospholipids and serum @entity2661 in strangulation. An experimental study on XXXX .

@entity548 :: ('MESH:D006470', 'Disease') :: ['haemorrhages'] @entity1425 :: ('MESH:D004837', 'Chemical') :: ['adrenaline'] @entity2434 :: ('MESH:D010713', 'Chemical') :: ['phosphatidyl choline'] @entity2415 :: ('MESH:D004646', 'Disease') :: ['emphysema'] @entity519 :: ('MESH:D000860', 'Disease') :: ['hypoxia'] @entity3633 :: ('MESH:C483858', 'Chemical') :: ['phosphatidyl ethanol amine'] @entity1763 :: ('MESH:D001237', 'Disease') :: ['asphyxia'] @entity2922 :: ('CHEBI:33567', 'Chemical') :: ['catecholamine'] @entity35 :: ('10116', 'Species') :: ['Rats', 'rats'] @entity2661 :: ('MESH:D002395', 'Chemical') :: ['catecholamines'] @entity1063 :: ('MESH:D009638', 'Chemical') :: ['noradrenaline']
@entity35 :: (10116,Species) :: ['rats']
