Prognostic factors and treatment outcome of 48 @entity1 with Stage I (29) or II (19) @entity1893 of the head and neck were analyzed retrospectively. There were 26 males and 22 females, aged from 15 to 89 years old, with an average age of 57. The @entity75 was located in @entity3521 in 25 @entity1 , the nasal cavity and paranasal sinuses in 13, cervical lymph nodes in 8, and others in 2. Histologically, 2 had @entity1893 , 42 had intermediate grade disease, and 1 had high grade disease. The @entity1 were treated with radiation alone (5 @entity1 ), chemotherapy according to a @entity786 , @entity632 , @entity1891 , @entity229 - (CHOP) regimen (8 @entity1 ), or a combination of both treatments (35 @entity1 ). In univariate analyses, an unfavorable prognosis was associated with age > or = 60, Stage I disease, and extralymphatic lesion. Multivariate analysis showed that an extralymphatic lesion was a significant independent risk factor for @entity204 (p = 0.0093). The overall five-year survival rate was 73.5%. Differences in the treatment was not reflected in the outcome. Our results suggest that a combination of chemotherapy (CHOP) and radiation is an appropriate treatment for lymphatic stage I and II @entity1893 of the head and neck. However, more intensive therapy is necessary for @entity1 with extralymphatic @entity135 .

[Statistical analysis of localized XXXX of the head and neck--multivariate analysis of prognostic factors and evaluation of therapeutic modalities].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity632 :: ('MESH:D004317', 'Chemical') :: ['doxorubicin'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck NHL'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesion'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide'] @entity3521 :: ('MESH:D012303', 'Disease') :: ["Waldeyer's ring"] @entity1891 :: ('MESH:D014750', 'Chemical') :: ['vincristine'] @entity1893 :: ('MESH:D008228', 'Disease') :: ["non-Hodgkin's lymphoma", 'low grade lymphoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1893 :: (MESH:D008228,Disease) :: ['non-Hodgkin's lymphomas']
