OBJECTIVE: To compare conventional treatment (heparin and @entity1229 ) of @entity49 with multimodality treatment (lysis and stenting). SUMMARY BACKGROUND DATA: Several studies have reported on conventional therapy for @entity49 with disappointing results. However, more recent studies have reported better results with multimodality treatment. METHODS: Fifty-one consecutive @entity1 with extensive @entity49 were treated during a 10-year period. If there were no contraindications, @entity1 were given the option to choose between conventional therapy (group 1) and multimodality therapy (group 2). The multimodality treatment strategy included catheter-directed lysis followed by percutaneous @entity661 (PTA) and stenting for residual iliac stenoses. All @entity1 underwent routine venous duplex imaging at 30 days, 3 months, 6 months, and every 6 months thereafter. RESULTS: There were 33 @entity1 in group 1 and 18 @entity1 in group 2. Demographic and clinical characteristics were comparable for both groups. Initial lysis was achieved in 16 of 18 @entity1 (89%) in group 2. Ten of 18 @entity1 in group 2 had residual stenosis after lysis (8 primary and 2 secondary to malignancy), and they were treated with @entity865 /stenting with an initial success rate of 90%. Two @entity1 in group 1 (6%) had a symptomatic @entity1151 (none in group 2). At 30 days, venous patency and symptom resolution were achieved in 1 of 33 @entity1 (3%) in group 1 versus 15 of 18 (83%) in group 2. Kaplan-Meier analysis showed primary iliofemoral venous patency rates at 1, 3, and 5 years of 24%, 18%, and 18% and 83%, 69%, and 69% for groups 1 and 2, respectively. Long-term symptom resolution was achieved in 10 of 33 @entity1 (30%) in group 1 versus 14 of 18 (78%) in group 2. Kaplan-Meier life table analysis showed similar survival rates at 1, 3, and 5 years of 100%, 93%, and 85% for group 1 and 100%, 93%, and 81% for group 2. CONCLUSIONS: Lysis/stenting treatment was more effective than conventional treatment in @entity1 with @entity715 .

Iliofemoral deep vein XXXX : conventional therapy versus lysis and percutaneous transluminal angioplasty and stenting.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity49 :: ('MESH:D019851', 'Disease') :: ['iliofemoral venous thrombosis'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['pulmonary embolism'] @entity865 :: ('CHEBI:61432', 'Chemical') :: ['PTA'] @entity661 :: ('MESH:D054549', 'Disease') :: ['transluminal balloon angioplasty'] @entity715 :: ('MESH:D013927', 'Disease') :: ['iliofemoral vein thrombosis'] @entity1229 :: ('MESH:D014859', 'Chemical') :: ['warfarin']
@entity715 :: (MESH:D013927,Disease) :: ['thrombosis']
