OBJECTIVE: The purpose of this study was to test the hypothesis that lack of microvascular reperfusion following revascularization might be associated with a poor clinical outcome in @entity6 @entity1 with @entity583 ( @entity583 ). METHODS: We studied 134 @entity1 with a first anterior @entity583 who underwent successful revascularization within 6 hours. We assessed microvascular reperfusion by using electrocardiogram recordings just before revascularization and on return to the coronary care unit. Lack of microvascular reperfusion was defined as the absence of decrease of > or = 20% in the sum of ST segment elevation (sigmaST). RESULTS: Twenty-four @entity1 had @entity6 and 110 @entity1 did not. SigmaST before revascularization was similar between @entity6 and nondiabetic @entity1 . After revascularization, reduction of sigmaST was significantly smaller (1.3 +/- 8.4 mm vs 6.5 +/- 10.8 mm, p = 0.03), and lack of microvascular reperfusion was significantly more frequent (62.5% vs 33.6%, p = 0.01) in @entity6 @entity1 . A multivariate analysis showed that @entity6 was associated with insufficient microvascular reperfusion (odds ratio 3.18, p = 0.03). Major adverse @entity299 occurred more frequently in @entity1 with a lack of microvascular reperfusion (30.8% vs 15.9%, p = 0.04). CONCLUSION: These findings suggest that lack of microvascular reperfusion following revascularization may be one of the mechanisms of a poor clinical outcome in @entity6 @entity1 with @entity583 .

@entity6 is associated with insufficient microvascular reperfusion following revascularization for anterior XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity583 :: ('MESH:D009203', 'Disease') :: ['AMI', 'acute myocardial infarction'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic', 'diabetes'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events']
@entity583 :: (MESH:D009203,Disease) :: ['acute myocardial infarction']
