OBJECTIVE: To bring to the attention of Urologists that the medication @entity15846 (Surgam, Albert-tiafen), a non-steroidal anti-inflammatory drug has been found to cause @entity2335 . METHODS: @entity1 presenting between November 1994 and November 1995 with a confirmed or presumed diagnosis of @entity2335 and who were taking @entity15846 are reported. RESULTS: Thirty-six @entity1 presented with a confirmed or presumed diagnosis of @entity2335 . One @entity1 without irritative symptoms presented with an abnormal ultrasound finding of a thickened bladder. Eight of these 37 @entity1 were diagnosed with @entity2335 from @entity15846 . These eight @entity1 (one @entity1 and seven @entity1 ) with ages ranging between 46 and 79 (mean 67 years), were taking @entity15846 from 22 to 84 months (mean 41.8 months), for the treatment of @entity571 . All eight @entity1 had findings of @entity32 at cystoscopy. Symptoms resolved from two to eight weeks (mean 5.3 weeks) in six out of the eight @entity1 (one @entity1 was asymptomatic and one is awaiting resolution two weeks after discontinuation), and persistence of @entity1494 (as seen on cystoscopy) lingered greater than three months in two @entity1 and five months one @entity1 , after the medication was stopped. CONCLUSION: Symptoms of frequency, @entity2183 and @entity158 are associated with long term ingestion of @entity15846 . Simple discontinuation of the drug will relieve symptoms usually within six weeks. The mechanism of @entity32 is unknown.

@entity15846 : an uncommon cause of @entity2335 often misdiagnosed as XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'woman', 'patient', 'man'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity2183 :: ('MESH:D053158', 'Disease') :: ['nocturia'] @entity571 :: ('MESH:D010003', 'Disease') :: ['osteoarthritis'] @entity1494 :: ('MESH:D001745', 'Disease') :: ['bladder inflammation'] @entity158 :: ('MESH:D010146', 'Disease') :: ['suprapubic pain'] @entity15846 :: ('MESH:C021270', 'Chemical') :: ['tiaprofenic acid'] @entity2335 :: ('MESH:D003556', 'Disease') :: ['chemical cystitis', 'interstitial cystitis']
@entity2335 :: (MESH:D003556,Disease) :: ['interstitial cystitis']
