OBJECTIVE: workers in slaughterhouses and processing plants that handle @entity1707 , and pork butchers/meatcutters have been little studied for health risks associated with employment, in spite of the fact that they are potentially exposed to oncogenic and non-oncogenic transmissible agents and chemical carcinogens at work. We report here on an update of mortality in 510 workers employed in abattoirs and processing plants that almost exclusively handled @entity1707 and pork products. METHODS: standardized mortality ratios (SMRs) were estimated for the cohort as a whole, and in subgroups defined by race and sex, using the corresponding US general population mortality rates for comparison. Study subjects were followed up from January 1950 to December 2006, during which time 45% of them died. RESULTS: mortality was significantly increased overall in the cohort. A statistically significant excess of @entity204 was observed for @entity2 in the entire cohort, @entity5047 =2.7 (95% CI, 1.2-5.1), @entity5047 =1.8 (95% CI, 1.1-2.7), respectively. Significant SMRs in the cohort as a whole were also observed for senile and pre-senile psychotic conditions ( @entity5047 =5.1, 95% CI, 1.4-13.1), and @entity55 ( @entity5047 =2.6, 95% CI, 1.3-4.8). An observed excess of @entity510 was seen mainly in whites ( @entity5047 =10.1, 95% CI, 1.2-36.3). There was a suggestion of an excess of @entity204 from @entity741 also, but the elevated @entity5047 was confined to @entity1 and was not statistically significant. CONCLUSION: this study confirms the excess occurrence of lung and @entity694 , and @entity64 previously reported in this occupational group. New findings are the excess of risk for senile and pre-senile psychotic conditions and @entity55 , which together with the excess of @entity694 appear specific for @entity1707 /pork workers, as they were not evident in much larger studies of workers in abattoirs and processing plants handling @entity291 and @entity742 . However, caution should be exercised in interpreting these findings, since some of them could have occurred by chance, resulting from our examination of a large number of causes of @entity204 in multiple study subgroups. For the moment, the significance of these findings remains unknown until they are confirmed in larger studies of adequate statistical power. Studies that will take into account possible occupational and non-occupational confounding factors are needed.

Mortality in workers employed in XXXX abattoirs and processing plants.

@entity1 :: ('9606', 'Species') :: ['men'] @entity1707 :: ('9823', 'Species') :: ['pigs', 'pig'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity742 :: ('9940', 'Species') :: ['sheep'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity510 :: ('MESH:D013345', 'Disease') :: ['subarachnoid hemorrhage'] @entity5047 :: ('147719', 'Gene') :: ['SMR'] @entity2 :: ('MESH:D008175', 'Disease') :: ['colon and lung cancers'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer', 'colon cancers'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'deaths'] @entity291 :: ('9913', 'Species') :: ['cattle']
@entity1707 :: (9823,Species) :: ['pig']
