It is well know that @entity731 can simultaneously affect different vascular subsystems, and @entity1 with @entity731 can be a major management problem both for preoperative evaluation and for intraoperative management. The authors have conducted a prospective study to evaluate the prevalence of @entity453 in arteriopathic @entity1 , and vice versa, to assess the effectiveness of @entity146 screening together with a priority-based approach. Study 1 consisted of 1,000 consecutive non-emergent @entity1 who were affected by abdominal aortic or @entity66 and were screened for the presence of @entity453 before surgery with a newly developed clinical risk assessment. They were stratified into three risk categories with different preoperative evaluation strategies. When @entity453 was concomitantly demonstrated in these @entity1 , the choice of surgical method was based on priorities, and the use of combined surgical procedures as required. In study 2, 1,000 consecutive @entity1 that required coronary angiography for suspected @entity453 were screened for the presence of carotid or abdominal aortic pathology, directly in the cardiac catheter laboratory during coronary angiography, by obtaining views of the aortic arch and abdominal aorta. Surgical approaches paralleled those of study 1. The results for study 1 showed that 720 @entity1 (72%) were affected by @entity2333 , 238 (24%) by @entity66 and 42 (4%) by both pathologies. Significant @entity453 was found in 152 @entity1 (15%), of these 123 (81.5%) were affected by @entity2333 and 29 (18.5%) by @entity2998 . Abdominal aortic surgery was performed directly or after myocardial revascularization, with an overall mortality rate of 4/718 (0.6%), and a perioperative @entity583 rate of 10/718 (1.4%). For @entity1 with @entity2998 , the completed screening and possible therapy for @entity453 resulted in an in-hospital mortality rate of 2/238 (0.8%), and a perioperative @entity583 rate of 2/238 (0.8%). There were no significant differences in these rates between @entity1 with or without @entity453 . Results for study 2 showed that of the 1000 consecutive @entity1 enrolled for suspicion of @entity453 , 767 (77%) were affected by significant @entity453 . Among these, 38 (4.9%) had a surgically correctable aortic disease and 31 (4%) a surgically correctable @entity66 , which was monolateral and bilateral in 22 (74%) and nine (26%) @entity1 , respectively, and four (0.5%) were diagnosed with both pathologies. These arteriopathic @entity1 were treated for their @entity301 with no in-hospital mortality nor perioperative @entity583 . In @entity1 with multiple vascular involvement, both coronary and vascular surgery can be performed with low risk when @entity146 screening and priority-based therapy are adopted.

Coronary and major vascular disease: XXXX screening and priority-based therapy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['carotid disease'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity301 :: ('MESH:D003327', 'Disease') :: ['coronary and vascular disease'] @entity2998 :: ('MESH:D002340', 'Disease') :: ['carotid artery disease'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity2333 :: ('MESH:D001018', 'Disease') :: ['abdominal aortic disease'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis', 'diffuse atherosclerosis']
@entity146 :: (MESH:D001523,Disease) :: ['aggressive']
