PURPOSE: @entity465 ( @entity465 ) are a group of @entity66 . Epidemiological studies from databases worldwide show geographical variation. In this study the objective is to determine the spectrum of @entity465 in Saudi Arabia by analyzing the database in a referral tertiary hospital. METHODS: This is a prospective data collection by interviews and medical chart review for all @entity465 @entity1 followed at the King Faisal Specialist Hospital _ Research Center (KFSH_RC) from May 2010 to April 2013. RESULTS: A total of 502 @entity1 presented (53  % male and 47  % female). Combined @entity465 were the most common (59.7  %), followed by @entity465 (12.3  %), @entity154 of phagocyte (9.4  %), @entity465 with associated or syndromic features (6.2  %), @entity1200 (6  %), @entity465 (5.8), and defects in innate immunity (0.6  %). The most common @entity465 phenotype was T-B- @entity915 (17  %). The @entity1 ' ages ranged from less than 1  year old to 78  years, and 394 @entity1 (78.2  %) are in the paediatrics age group (<14  years). The overall mean age of symptoms onset was 17  months and the overall mean delay in diagnosis was 21.6  months. Recurrent @entity281 were the most common occurring clinical presentation (66  %), followed by family history (26  %). Consanguinity was found in 75  % of the @entity1 . A total of 308 (61  %) @entity1 had undergone @entity8 ( @entity8 ). CONCLUSION: The study revealed that @entity465 are not uncommon and are the most frequent occurring diagnosis in our @entity1 population. This study is a prerequisite to establish a national registry of @entity465 in Saudi Arabia.

XXXX in Saudi Arabia: a Tertiary Care Hospital Experience over a Period of Three Years (2010-2013).

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity154 :: ('MESH:D000013', 'Disease') :: ['congenital defects'] @entity8 :: ('MESH:D007674', 'Disease') :: ['SCT', 'stem cell transplantation'] @entity66 :: ('MESH:D004194', 'Disease') :: ['heterogeneous diseases'] @entity915 :: ('MESH:D053632', 'Disease') :: ['SCID'] @entity465 :: ('MESH:D007153', 'Disease') :: ['combined immunodeficiencies', 'primary immunodeficiency', 'PID', 'predominantly antibody deficiencies', 'complement deficiencies', 'Primary immunodeficiencies', 'immunodeficiencies'] @entity1200 :: ('MESH:D007154', 'Disease') :: ['disease of immune dysregulation'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections']
@entity1200 :: (MESH:D007154,Disease) :: ['Primary Immunodeficiency Diseases']
