OBJECTIVE: @entity74 with @entity1188 and @entity62 (CADASIL) is an @entity455 characterized by @entity2704 , cerebrovascular events, and @entity73 . Although recognized as a cardinal feature of the disease, @entity146 disturbances have rarely been the object of focused studies. We performed a structured evaluation of @entity1316 in CADASIL. MATERIALS AND METHODS: Twenty-three @entity1 with CADASIL (five @entity1 and 18 @entity1 ) were assessed by psychiatrists using the Structured Clinical Interview for the DSM-IV, clinician version. For the quantitative assessment of current @entity1316 symptoms, the Hamilton Rating Scale for @entity308 (HRSD) and the Young Mania Rating Scale (YMRS) were used. RESULTS: A lifetime @entity308 was recorded in 17/23 (73.9%) @entity1 with CADASIL. Six (26.1%) @entity1 with CADASIL reported a current @entity308 . A diagnosis of manic lifetime episode was made in 6 (26.1%) @entity1 with CADASIL. The HRSD mean score in @entity1 with current @entity308 was 9.1    SD 8.1. The YMRS mean score was 14.2    SD 4.1 for @entity19606 . CONCLUSION: This study confirms that @entity1316 are frequent in CADASIL. The use of a structured @entity146 interview outlines a frequency of @entity308 higher than that previously reported but also reveals a considerable frequency of @entity162 . If confirmed in larger series, these data suggest that a greater attention should be paid to the @entity146 aspects in CADASIL.

XXXX and @entity162 in CADASIL: a study using the DSM-IV semi-structured interview.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity162 :: ('MESH:D001714', 'Disease') :: ['bipolar disorders'] @entity455 :: ('MESH:D014652', 'Disease') :: ['inherited cerebral microangiopathy'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression', 'depression', 'depressive episode'] @entity146 :: ('MESH:D001523', 'Disease') :: ['psychiatric'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment'] @entity2704 :: ('MESH:D008881', 'Disease') :: ['migraine'] @entity1316 :: ('MESH:D019964', 'Disease') :: ['mood disorder', 'mood disorders'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['subcortical infarcts'] @entity19606 :: ('MESH:D046589', 'Disease') :: ['manic CADASIL'] @entity74 :: ('MESH:D030342', 'Disease') :: ['Cerebral autosomal dominant arteriopathy'] @entity62 :: ('MESH:D056784', 'Disease') :: ['leukoencephalopathy']
@entity308 :: (MESH:D003866,Disease) :: ['Major depression']
