BACKGROUND: @entity1 with intractable @entity5 often require non-pharmacological analgesic treatment that is accompanied by procedure-related @entity158 . Previous works have shown that @entity1875 infusion in adjunction to regional anesthesia provides appropriate sedation during such @entity158 procedures. However, there are a few reports of its use to reduce procedure-related @entity158 in @entity5 @entity1 . We report cases of @entity1875 sedation during percutaneous vertebroplasty ( @entity12468 ) in @entity1 with metastatic vertebral compression @entity174 . METHODS: @entity1875 was infused during @entity12468 in eleven @entity5 @entity1 after obtaining written informed consent. The infusion rate of @entity1875 was adjusted using a target-controlled infusion pump to achieve appropriate sedation levels under monitoring bispectral index of the electroencepharogram. Hepatic and renal functions were evaluated using common serum markers, which were determined using standard hospital laboratory methods. RESULTS: The duration of the procedure was 65.5 +/- 5.5 (mean +/- SD) min. The required infusion rate was 8.66 +/- 1.50 mg.kg-1.hr-1. The interval from the termination of the infusion until emergence was 10.7 +/- 4.2 min. No life-threatening complications or significant changes in liver and renal functions were observed. CONCLUSIONS: @entity1875 can be used effectively and safely for sedation during @entity12468 in @entity5 @entity1 .

[Use of XXXX for @entity158 procedures in @entity5 management].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'terminal cancer', 'cancer pain'] @entity12468 :: ('CHEBI:53245', 'Chemical') :: ['PVP'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol', 'Propofol'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'painful']
@entity1875 :: (MESH:D015742,Chemical) :: ['propofol']
