BACKGROUND: To evaluate the results of intravitreal bevacizumab in terms of regression of @entity989 ( @entity989 ). METHODS: In this interventional case series, 12 eyes from January 2007 to December 2008 were included. Two groups of @entity1 were considered. Group 1 included those @entity989 @entity1 who did not respond to conventional laser therapy within 3  weeks or had some complications ( @entity5891 or @entity548 ) after conventional laser therapy; intravitreal injection (0.625  mg) was performed as an adjuvant therapy. Group 2 included those with @entity146 posterior @entity989 who received single intravitreal bevacizumab injection as the initial treatment. RESULTS: Ten eyes of 12 @entity1 with mean gestational age of 28.5 (range: 26-32) weeks and birth weight of 1,218 grams (range: 900-1,630) were included in the study. Mean conceptional age at the time of first visit was 40  weeks (30-48  weeks). All the @entity1 had a history of supplemental @entity26 . Eight @entity1 (26.3%) were under mechanical ventilation. Eight eyes received bevacizumab after conventional laser therapy (group 1). Four eyes received intravitreal bevacizumab as the initial therapy (group 2). All of the @entity1 were followed up for at least 1  year. All @entity1 in group 1 responded to this adjuvant (intravitreal bevacizumab) treatment within 1  week, but two eyes of group 2 needed laser therapy 1.5  month after intravitreal bevacizumab injection in spite of the initial treatment response. No complications such as @entity231 , @entity3225 or @entity1713 occurred. CONCLUSIONS: The use of intravitreal bevacizumab injection in premature eyes was well-tolerated, and induced prompt regression as an adjuvant therapy after conventional laser therapy and also as an alternative therapy in the management of @entity146 @entity989 .

Intravitreal bevacizumab in XXXX : an interventional case series.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['vitreous hemorrhage'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['retinal detachment'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity989 :: ('MESH:D012164', 'Disease') :: ['retinopathy of prematurity', 'ROP'] @entity5891 :: ('MESH:D006988', 'Disease') :: ['hyphema'] @entity3225 :: ('MESH:D009877', 'Disease') :: ['endophthalmitis']
@entity989 :: (MESH:D012164,Disease) :: ['retinopathy of prematurity']
