INTRODUCTION: Observer variability can influence the assessment of CT coronary angiography (CTCA) and the subsequent diagnosis of @entity951 due to @entity301 . METHODS: We assessed 210 CTCAs from the Scottish COmputed Tomography of the HEART ( @entity29538 ) trial for intraobserver and interobserver variability. @entity460 score, coronary angiography and image quality were evaluated. @entity453 was defined as none (<10%), mild (10-49%), moderate (50-70%) and severe (>70%) luminal stenosis and classified as no (<10%), non-obstructive (10-70%) or obstructive (>70%) @entity453 . Post-CTCA diagnosis of @entity951 due to @entity301 was classified as yes, probable, unlikely or no. RESULTS: @entity1 had a mean body mass index of 29 (28, 30) kg/m(2), heart rate of 58 (57, 60)/min and 62% were @entity1 . Intraobserver and interobserver agreements for the presence or absence of @entity453 were excellent (95% agreement, k 0.884 (0.817 to 0.951) and good (91%, 0.791 (0.703 to 0.879)). Intraobserver and interobserver agreement for the presence or absence of @entity951 due to @entity301 were excellent (93%, 0.842 (0.918 to 0.755) and good (86%, 0.701 (0.799 to 0.603)), respectively. Observer variability of @entity460 score was excellent for @entity460 scores below 1000. More segments were categorised as uninterpretable with 64-multidetector compared to 320-multidetector CTCA (10.1% vs 2.6%, p<0.001) but there was no difference in observer variability. CONCLUSIONS: Multicentre multidetector CTCA has excellent agreement in @entity1 under investigation for suspected angina due to @entity301 . TRIAL REGISTRATION NUMBER: NCT01149590.

Observer variability in the assessment of CT coronary angiography and coronary artery @entity460 score: substudy of the Scottish COmputed Tomography of the HEART ( XXXX ) trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity301 :: ('MESH:D003327', 'Disease') :: ['coronary heart disease'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina pectoris'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium', 'Calcium'] @entity29538 :: ('5019', 'Gene') :: ['SCOT-HEART'] @entity453 :: ('MESH:D003324', 'Disease') :: ['Coronary artery disease', 'coronary artery disease']
@entity29538 :: (5019,Gene) :: ['SCOT-HEART']
