OBJECTIVE: To discuss the rationality and clinical significance of @entity348 ( @entity348 ) assessed by the pattern of local recurrence of @entity5 . METHODS: 207 @entity5 @entity1 treated by surgery from 1975 to 2001 who developed local recurrence were retrospectively studied as to the option of treatment based on their outcome. 172 of these 207 @entity1 had complete record of follow-up with a follow-up rate of 83.0%. RESULTS: The local recurrent sites of 207 @entity1 were: anastomotic stoma 71, mesorectum 65, perineum 50, lymph nodes 59, multiple recurrences 89 and others sites rare. Among 81 @entity1 who had been first treated by anterior resection (AR), 58 were again treated by abdomino-perineal resection (APR). Among 102 @entity1 who had been treated by APR, 38 were treated by perineal @entity5 resection, 15 were treated by total and posterior pelvic organ resection, and 18 were supplemented with lymph node resection. By all modalities, the resection rate was 66.1% (137/207), in which the curable resection rate was 46% (63/137). The 5-year survival rate of @entity1 with @entity5 resection was 23.3% (32/137), those treated by curable resection was 34.9% (22/63). CONCLUSION: From the pattern of local recurrence, the operation for @entity5 must follow the principle of @entity348 ( @entity348 ). @entity1 with local recurrence should be energetically treated in the second operation if tolerable.

[On rationality of XXXX for @entity5 ].

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'middle-lower rectal cancer', 'rectal cancer'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity348 :: ('MESH:C535338', 'Disease') :: ['total mesorectum excision', 'TME', 'total mesorectal excision']
@entity348 :: (MESH:C535338,Disease) :: ['total mesorectal excision']
