Various foot structures are thought to influence forefoot plantar pressures during walking. High @entity551 ( @entity551 ) during walking in @entity1 with @entity6 ( @entity6 ) and @entity1897 ( @entity1897 ) can cause skin breakdown. The question addressed by this study is "What are the primary forefoot structural factors that predict regional @entity551 during walking in groups of @entity1 with and without @entity6 and @entity1897 ?" Twenty @entity1 with @entity6 and @entity1897 (mean age 55+/-9 years, 6 female, 14 male, BMI=33+/-8) and 20 @entity1 without @entity6 , matched for gender, age, and BMI were tested. Measures of foot structure were taken from three-dimensional images constructed from spiral X-ray computed tomography. Peak plantar pressure data were recorded during walking. Hierarchical multiple regression analysis was used to predict regional @entity551 at the great toe and five metatarsal heads from selected structural and walking variables. Metatarsal phalangeal joint angle ( @entity85 ) was the most important variable predicting pressure, accounting for 19-45% of the @entity551 variance at five of the six locations in the @entity6 group. Soft tissue thickness, @entity4553 , and forefoot @entity2720 were the most important predictors of @entity551 in the control group. Combinations of structural and walking variables accounted for 47-71% of the variance in the @entity6 group and 52-83% of the variance of @entity551 during walking in the control group. These structural variables, especially @entity85 , should be considered in attempts to develop strategies to reduce excessive forefoot @entity551 that may contribute to skin breakdown or other injury.

Forefoot structural predictors of plantar pressures during walking in @entity1 with XXXX and @entity1897 .

@entity1 :: ('9606', 'Species') :: ['people'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus', 'DM'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['PN', 'peripheral neuropathy'] @entity4553 :: ('MESH:D006215', 'Disease') :: ['hallux valgus'] @entity2720 :: ('MESH:D007592', 'Disease') :: ['arthropathy'] @entity85 :: ('MESH:D009140', 'Disease') :: ['hammer toe deformity'] @entity551 :: ('MESH:D007022', 'Disease') :: ['PPP', 'peak plantar pressures']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes']
