UNASSIGNED: <strong>Objective </strong> To evaluate the feasibility of three-dimensional pseudo-continuous arterial @entity7959 label (3D pCASL) non-contrast enhanced perfusion imaging applied to head and @entity135 in high-field MR and detect the effects of different postlabeling delay (PLD) time on image quality and the reliability of repeated measurements of @entity5 blood flow (BF) in different 3D pCASL groups. <strong>Methods </strong> In this prospective study,all the 25 @entity1 received neck 3D pCASL non-contrast enhanced perfusion examinations in a 3.0 T MR system by using an 8-channel head and neck joint coil. Conventional T1-weighted(TIWI) and T2-weighted imaging (T2WI) were performed firstly. Finally,three 3D pCASL with different PLD time[ASL1(PLD1=1525 ms),ASL2(PLD2=2025 ms),ASL3(PLD3=2525 ms)]were acquired. @entity1 ' perfusion-weighted images acquired from different 3D pCASL sequences underwent the analysis of signal to noise ratio (SNR) and contrast noise ratio (CNR) for @entity5 . Two observers performed the qualitative assessments on spiral artifacts and vascular artifacts of perfusion-weighted images from different 3D pCASL sequences. Blood flow (BF) of @entity5 from different 3D pCASL sequences were measured by the two observers respectively for the first time and by observer 2 for the second time. <strong>Results </strong> Seventeen enrolled @entity1 (age:50.1  12.7 years,M/F=10:7) with histopathologic <strong>Results </strong> underwent the evaluation of image quality and measurements of BF values. The SNRs and CNRs of ASL1,ASL2,and ASL3 showed a descending trendency. SNRs (P=0.011)and CNRs(P=0.009) of ASL1 were significant higher than those of ASL3. There was no significant difference of scores of spiral artifacts among the three ASL groups (P=0.932). The scores of vascular artifacts of ASL1,ASL2,and ASL3 showed a descending trendency,also. And scores of ASL1 was significant higher than that of ASL3(P=0.000). The intraclass correlation coefficient (ICC) of intre-and intraobserver were high (ICC>0.9). Although the BF values of ASL1,ASL2,and ASL3 showed an ascending trendency,there was no significant difference among the three groups (P=0.977). <strong>Conclusion </strong>s The 3D pCASL no-contrast enhanced perfusion MR imaging can be used for @entity135 . The image quality of perfusion weighted images and reliability of BF measurements were satisfied. The 3D pCASL series with PLD of 1525 ms and 2025 ms have better image quality than PLD of 2525 ms. And BF values do not show significant statistic difference among the three groups. Therefore,3D pCASL series with PLD of 1525 ms and 2025 ms are more suitable for the perfusion imaging of head and @entity135 .<br/>.

Three-dimensional Pseudo-continuous Arterial @entity7959 Label Non-contrast Enhanced Perfusion Imaging of XXXX with High-field MR System.

@entity7959 :: ('10927', 'Gene') :: ['spin'] @entity135 :: ('MESH:D006258', 'Disease') :: ['neck tumors', 'head and neck tumor'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors']
@entity135 :: (MESH:D006258,Disease) :: ['Head and Neck Tumors']
