OBJECTIVE: To compare the effectiveness of @entity3429 , @entity585 , and @entity1482 in the treatment of idiopathic @entity3427 . DESIGN: Prospective randomized clinical study. SETTING: University hospital. @entity1 (S): Forty-one @entity1 (median age, 21 years [range, 18-34 years]) with idiopathic @entity3427 who had requested to use an oral contraceptive. INTERVENTION(S): @entity1 were randomly assigned to receive @entity3429 (12.5 mg/d for the first 10 days of the cycle), @entity585 (5 mg/d), or @entity1482 (100 mg/d) for 12 months. Follow-up was done at the end of therapy. MAIN OUTCOME MEASURE(S): Ferriman-Gallwey score before treatment, at 6 and 12 months of treatment, and 1 year after the end of treatment, and androgenic profile before and after treatment. RESULT(S): At the end of therapy, the Ferriman-Gallwey score decreased by 38.9%, 38.6%, and 38.5% in @entity1 who used @entity3429 , @entity585 , and @entity1482 , respectively. One year after therapy, the Ferriman-Gallwey score of @entity1 who used @entity1482 was significantly lower (6.74 +/- 1.41) than that of @entity1 who used either @entity3429 (7.92 +/- 1.08), or @entity585 (9.08 +/- 0.99). The androgenic profile did not change significantly during treatment. CONCLUSION(S): In @entity1 with idiopathic @entity3427 , the short-term results of treatment with @entity3429 , @entity585 , and @entity1482 are similar, but @entity1482 is effective for a longer time.

Use of @entity3429 , XXXX , and @entity1482 to treat idiopathic @entity3427 .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'PATIENT'] @entity3429 :: ('MESH:D017373', 'Chemical') :: ['cyproterone acetate'] @entity585 :: ('MESH:D018120', 'Chemical') :: ['finasteride'] @entity1482 :: ('MESH:D013148', 'Chemical') :: ['spironolactone'] @entity3427 :: ('MESH:D006628', 'Disease') :: ['hirsutism']
@entity585 :: (MESH:D018120,Chemical) :: ['finasteride']
