BACKGROUND: Radiological characteristics may reflect the biological features of @entity1313 and may be associated with genetic alterations that occur in tumorigenesis. This study aimed to investigate the relationship between radiological features and @entity818 status as well as their predictive value for survival of @entity463 @entity1 . METHODS: The clinical information and MR images of 280 @entity1 with histologically confirmed @entity463 were retrospectively reviewed. The radiological characteristics of @entity5 were examined on MR images, and the @entity818 status was determined using DNA sequencing for all cases. The Kaplan-Meier method and Cox regression model were used to identify prognostic factors for progression-free and overall survival. RESULTS: The @entity818 mutation was associated with longer progression-free survival (P = .022; hazard ratio, 0.602) and overall survival (P = .018; hazard ratio, 0.554). In @entity1 with the @entity818 mutation, @entity5 contrast enhancement and peritumoral @entity4 indicated worse progression-free survival (P = .015 and P = .024, respectively) and worse overall survival (P = .024 and P = .032, respectively). For @entity5 with contrast enhancement, multifocal contrast enhancement of the @entity5 lesion was associated with poor progression-free survival (P = .002) and poor overall survival (P = .010) in @entity1 with wild-type @entity818 @entity5 . CONCLUSIONS: Combining the radiological features and @entity818 status of a @entity5 allows more accurate prediction of survival outcomes in @entity463 @entity1 . The complementary roles of genetic changes and radiological features of @entity5 should be considered in future studies.

Radiological features combined with @entity818 status for predicting the survival outcome of @entity463 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['brain tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity818 :: ('3417', 'Gene') :: ['IDH1'] @entity463 :: ('MESH:D005909', 'Disease') :: ['glioblastoma']
@entity1 :: (9606,Species) :: ['patients']
