AIM: To evaluate the clinical effects of laser therapy on the prevention and @entity3136 in @entity1 who underwent @entity8 ( @entity8 ). @entity1 AND METHODS: From January 2003 to September 2004, 24 @entity1 received prophylactic laser therapy (L+ group). The applications started from the beginning of the conditioning regimen up to day +2. The oral assessment was performed daily until day +30. This group was compared with historical controls, namely 25 @entity1 , who did not receive laser therapy (L- group). RESULTS: All @entity1 developed some grade of @entity33 . However, the L- group presented initial @entity33 by 4.36 days, whereas the L+ group presented it in 6.12 days (P = 0.01). The maximum @entity33 occurred between day +2 and day +6 with healing by day +25 in the L- group and between day +2 and day +7 with healing by day +14 for the L+ group (P = 0.84). Laser therapy also reduced the time of @entity158 from 5.64 to 2.45 days (P = 0.04), and decreased the consumption of @entity1286 (P = 0.07). CONCLUSION: This study suggests that laser therapy can be useful in @entity3136 to @entity8 @entity1 and improve the @entity1 's quality of life. However, controlled randomized trials should be performed to confirm the real efficacy of laser therapy.

Low-energy laser therapy for prevention of @entity3136 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity8 :: ('MESH:D007674', 'Disease') :: ['hematopoietic stem cell transplantation', 'HSCT'] @entity3136 :: ('MESH:D013280', 'Disease') :: ['oral mucositis', 'reduction of oral mucositis'] @entity33 :: ('MESH:D052016', 'Disease') :: ['mucositis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['oral pain'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine']
@entity8 :: (MESH:D007674,Disease) :: ['hematopoietic stem cell transplantation']
