BACKGROUND: @entity409 is a major cause of morbidity and mortality worldwide. Large numbers of liver function tests (LFTs) are performed in primary care, with abnormal liver biochemistry a common finding. @entity1561 ( @entity1561 ) is the most common cause of @entity7009 . @entity209 , common in @entity1 from South Asia, is an important risk factor for @entity1561 . AIM: It is hypothesised that a large gap exists between numbers of @entity1 with abnormal LFTs and those with recorded liver diagnoses, and that @entity1561 is more common among adults of South Asian ethnic groups. DESIGN AND SETTING: A cross-sectional study of 690,683 adults in coterminous general practices in a region with high ethnic diversity. METHOD: Data were extracted on LFTs, @entity409 , and process of care measures from computerised primary care medical records. RESULTS: LFTs were performed on 218,032 @entity1 , of whom 31 627 had elevated serum transaminases. The prevalence of abnormal LFTs was highest among individuals of Bangladeshi ethnicity. Of the @entity1 with abnormal LFTs, 88.4% did not have a coded liver diagnosis. @entity1561 was the most frequently recorded @entity409 and was most common among Bangladeshi @entity1 . In a multivariate analysis, independent risk factors for @entity1561 included Bangladeshi ethnicity, @entity6 , raised BMI, @entity101 , and hypercholesterolaemia. CONCLUSION: Abnormal LFTs are common in the population, but are underinvestigated and often remain undiagnosed. Bangladeshi ethnicity is an important independent risk factor for @entity1561 .

Ethnicity and the diagnosis gap in XXXX : a population-based study.

@entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity409 :: ('MESH:D008107', 'Disease') :: ['Liver disease', 'liver disease'] @entity7009 :: ('MESH:D056487', 'Disease') :: ['chronic liver injury'] @entity1561 :: ('MESH:D065626', 'Disease') :: ['NAFLD', 'Non-alcoholic fatty liver disease'] @entity209 :: ('MESH:D008659', 'Disease') :: ['Metabolic syndrome']
@entity409 :: (MESH:D008107,Disease) :: ['liver disease']
