UNASSIGNED: @entity135 ( @entity135 ) is a rare and aggressive @entity5 . The objective of this study was to describe the outcomes of @entity1 with @entity135 . Clinical and pathological data from 51 @entity1 with primary @entity135 were reviewed. All @entity1 were treated at a single @entity5 centre between 1954 and 2012. Most @entity5 involved the nasal cavity (35.3%) and upper gingiva (29.4%). The majority of lesions were ulcerated (54.9%) and pigmented (84.3%). Forty-three @entity1 underwent surgical treatment and 21 (41.2%) underwent adjuvant chemotherapy and/or radiotherapy. Eight @entity1 (15.7%) received palliative treatment. The median follow-up period was 21 months. During this period, 30 (58.8%) @entity1 had @entity5 recurrences. At the last clinical evaluation, only seven (13.7%) @entity1 were alive with no evidence of disease and three (5.9%) were alive with @entity135 . There were significant differences in overall survival probability according to the presence of @entity1066 (P=0.004), metastatic lymph nodes (P=0.003), and treatment including a radical surgical procedure (P<0.001). On multivariate analysis, @entity1066 was the only variable associated with an increased risk of @entity204 . Despite the poor prognosis, there was significant improvement in overall survival in the most recent years in this sample, mainly due to advances in diagnosis and reconstruction techniques.

@entity135 : clinicopathological analysis of 51 cases treated in a single XXXX centre and review of the literature.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity135 :: ('MESH:D006258', 'Disease') :: ['HNMM', 'Head and neck mucosal melanoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'tumours', 'malignancy', 'tumour'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulceration'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
