The objective of this study was to develop a @entity191 diary that evaluates a @entity1 's difficulties in performing activities as a substitute for the amount of "on"- and "off"-time and to assess its clinimetric qualities. In this study, 84 @entity1 with @entity191 kept a diary for 2 or 3 periods of 5 days. Daily, five items were recorded across 11 time periods. @entity1 simultaneously recorded "on-off" in the traditional way. The diary was easily understood, and median recording time was 5-10 minutes a day. Clinimetric analysis showed that the diary could be reduced successfully to 3 days, in which five items (walking, transfers, manual activities, @entity910 , and sleep) with four response options (no, slight, moderate, and severe difficulty) were assessed seven times daily. Sumscores of the first three items accurately predicted being "on" or "off" in 93% of the cases, making separate scoring of "on" and "off" unnecessary. The diary was internally consistent and showed good reproducibility. Construct validity with external measures was adequate, and comparisons between @entity1 grouped by disease severity and by degree of fluctuations revealed significant differences in the expected directions. Taken together, this @entity191 diary has a sound clinimetric basis, provides information on the extent of perceived disability, and thereby accurately reflects the severity of "off"-periods and the variability of motor fluctuations.

Activity-based diary for XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity910 :: ('MESH:D004409', 'Disease') :: ['dyskinesias'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease"]
@entity191 :: (MESH:D010300,Disease) :: ['Parkinson's disease']
