PURPOSE OF INVESTIGATION: @entity124 ( @entity124 ) is a hallmark of defective mismatch repair and is present in approximately 20% of @entity43 . It is not known if the presence of @entity124 predicts survival in @entity1 with @entity43 . MATERIALS AND METHODS: Cases of @entity43 were ascertained from a population-based study in Ontario and @entity5 samples were tested for @entity124 , using five @entity124 markers. @entity1 were divided into @entity124 -high and @entity124 -low/normal, according to National @entity5 Institute criteria. The authors compared the prevalence of specific prognostic factors in the two subgroups, including age, grade, stage, and histology. They estimated the hazard ratio for @entity204 from @entity43 associated with @entity124 -high and with other prognostic factors using a multi-variate analysis. RESULTS: A total of 418 @entity43 @entity1 were included. One hundred and twenty-seven (19.7%) @entity5 were @entity124 - high. Subgroup analyses did not reveal any statistically significant differences for pathologic features associated with @entity124 status. No survival difference was seen according to @entity124 status. CONCLUSIONS: The presence of @entity124 in @entity43 is not associated with survival.

Survival in @entity1 with XXXX with and without microsatellite instability.

@entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian cancers', 'ovarian cancer', 'epithelial ovarian cancer'] @entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity124 :: ('MESH:D053842', 'Disease') :: ['Microsatellite instability', 'MSI'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cancer', 'cancers', 'tumour'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity43 :: (MESH:D010051,Disease) :: ['ovarian cancer']
