OBJECTIVE: The aim of this study was to assess the predictive value of neutrophil/lymphocyte and platelet/lymphocyte ratios for borderline, @entity43 , and borderline cases with microinvasion. METHODS: Totally 275 @entity1 with sonographically detected @entity43 were enrolled for this study. All subjects underwent gynecological surgery via endoscopic or conventional approach and ovarian masses were all evaluated histopathologically by the same pathologist. All study population was divided into three groups as group with borderline @entity5 , @entity5 , or @entity5 according to the histopathological diagnosis. Just before surgical intervention, a blood sample was obtained from each @entity1 to analyze @entity10224 level, neutrophil, platelet, and lymphocyte count. RESULTS: Neutrophil/lymphocyte ratio (AUC  =  0.604, P  =  0.02) was a significant predictor for malignant cases. Optimal cutoff value for the neutrophil/lymphocyte ratio was found to be 2.47 with 63.4  % sensitivity and 63.5  % specificity for @entity5 prediction. Odds ratio of high neutrophil/lymphocyte ratio for @entity5 risk was 2.5 (95  % CI 1.3-4.8, P  =  0.004). Platelet/lymphocyte ratio (AUC  =  0.621, P  =  0.007) was a significant predictor for malignant cases. Platelet/lymphocyte ratio (AUC  =  0.568, P  =  0.05) was also predictive for cases without a benign mass. Optimal cutoff value for the platelet/lymphocyte ratio was found to be 144.3 with 54  % sensitivity and 59  % specificity for @entity5 prediction. Odds ratio of high platelet/lymphocyte ratio for @entity5 risk was 2.1 (95  % CI 1.1-3.8, P  =  0.02). CONCLUSION: Neutrophil/lymphocyte and platelet/lymphocyte ratios are predictors for @entity43 but not borderline @entity5 even in case of microinvasion.

Neutrophil to lymphocyte and platelet to lymphocyte ratios increase in XXXX in the presence of frank stromal invasion.

@entity43 :: ('MESH:D010051', 'Disease') :: ['malignant ovarian tumors', 'ovarian tumor'] @entity1 :: ('9606', 'Species') :: ['women', 'participant'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant tumors', 'benign tumors', 'malignancy', 'tumors'] @entity10224 :: ('94025', 'Gene') :: ['CA125']
@entity43 :: (MESH:D010051,Disease) :: ['ovarian tumors']
