@entity56 , particularly @entity565 and @entity565 equivalents, are among the most frequent disorders seen in the pediatric clinic. Approximately 25% of @entity1 from developed countries have presented wheezing in recent years, and half of these @entity1 later experience major @entity565 attacks. Likewise, 25% of @entity1 between 8 and 11 years have at some time used beta agonists and at least 10% of them use preventive @entity565 medication. Prevention measures for @entity56 include: 1) avoiding allergic sensitization; 2) avoiding the presentation of disease in sensitized @entity1 ; and 3) preventing symptoms after the disease has appeared. @entity56 have a multifactorial origin that includes genetic, perinatal, and specific and non-specific environmental factors. From a genetic point of view, @entity565 is a multifactorial and heterogeneous pathology with a variable degree of penetration and phenocopy. @entity566 is more frequent among the offspring of @entity6160 . Genetic variations in different chromosomes affect molecules and receptors involved in atopy: IgE elevation, Fce1 receptor and chromosome 11; @entity3646 ; gamma interferon and chromosome 12; @entity6057 a/d receptor and chromosome 14; @entity6057 and chromosome 7; and the main histocompatibility complex HLA I and II and chromosome 6. Likewise, it has been confirmed that genetic variants affect structures in the impact organs, such as the beta 2 receptors of IL-4 soluble receptors, which favor @entity6587 . Recently, somatometric measures have been related (low weight and large head circumference at birth) with a later increase in IgE and the occurrence of @entity565 . The environmental factors most closely involved in the occurrence of @entity565 are: diet (early exposure to sensitizing foods); domestic, outside, and occupational seroallergens; pollution (particularly smoking and urban and industrial pollution); and @entity281 , particularly @entity1800 . In the present study, the methods used for the early identification of @entity1 at risk are evaluated, as well as the role of the primary care pediatrician in the early detection of allergic @entity1 and the interventions that they carry out. Finally, an analysis is made of the preventive measures that should be taken in @entity1 at risk of @entity56 , particularly: 1) increasing awareness of health, 2) reduction of exposure to smoking. 3) reduction of urban and industrial pollution, 4) delayed introduction of certain foods, reduction in the level of domestic allergens, 6) control of @entity281 , and 7) pharmacological measures designed to prevent the occurrence of @entity565 in @entity1 .

[Preventive measures for XXXX ].

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity6160 :: ('MESH:D063129', 'Disease') :: ['atopic parents'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity566 :: ('MESH:D006967', 'Disease') :: ['Allergy'] @entity6057 :: ('6962', 'Gene') :: ['TcR-beta', 'TcR'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral infections'] @entity56 :: ('MESH:D004342', 'Disease') :: ['allergic disease', 'allergic asthma', 'Allergic diseases'] @entity3646 :: ('3565', 'Gene') :: ['IL-4 and chromosome 3'] @entity6587 :: ('MESH:D016535', 'Disease') :: ['bronchial hyperreactivity']
@entity56 :: (MESH:D004342,Disease) :: ['allergic diseases']
