UNASSIGNED: Our purpose was to evaluate the efficacy of stereotactic radiotherapy (SRT) for intracranial and extracranial @entity3 in @entity1 with @entity1358 . The retrospective analysis of 85 @entity1 (151 @entity5 ) treated with SRT was performed. SRT was the sole treatment in 35% of @entity5 , the other 65% had received additional treatment such as surgery, palliative radiotherapy, immunotherapy or chemotherapy. In 60% and 40% of @entity1 SRT was delivered to brain and extracranial lesions, respectively. The assessment of the efficacy of SRT was based on a  radiological imaging (Computed Tomography or Magnetic Resonance Imaging) and estimation of Local Control (LC) as well as @entity1349 ( @entity1349 ). Single fraction was used for 104 @entity5 and fractionated treatment for 47 @entity5 . The crude LC for evaluable lesions was 81%, stratified by @entity5 location: brain LC=94%, extracranial @entity5 LC=70% (p=0.049). The median @entity1349 was 9.4 months; 1-year and 2-year @entity1349 were 40% and 29%, respectively. The additional treatment did not lead to a  better local response (p=0,543), but resulted in a  benefit in @entity1349 (7 vs 13 months, p=0,01). A  positive relationship between the @entity10204 ( @entity10204 ) and local response was noted, but the @entity10204 was influenced by a  @entity5 volume (R=-0,38; p<0,00001). The presence of multi-organ @entity3 reduced the @entity1349 rate (8.7 vs 19.1 months; p=0,01). The interval between the diagnosis of the @entity3 and its treatment with SRT was inversely related to @entity1349 (P=0.0001). SRT results in a  good local response, which is more beneficial for brain than extracranial lesions. The local efficacy of the SRT depends on the radiation dose. Multidisciplinary treatment and earlier application of SRT improves the prognosis of @entity1 .

The efficacy of stereotactic radiotherapy for @entity3 from XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity10204 :: ('MESH:D021081', 'Disease') :: ['biologically effective dose', 'BED'] @entity1358 :: ('MESH:D002292', 'Disease') :: ['renal cell carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'Overall Survival']
@entity1358 :: (MESH:D002292,Disease) :: ['renal cell carcinoma']
