STUDY DESIGN: A retrospective review of transpedicular instrumentation used in a series of 24 @entity1 with myelodysplastic @entity85 and @entity1417 . OBJECTIVE: To describe the usefulness and efficacy of these instruments in the treatment of complicated myelodysplastic @entity85 . METHODS: The mean preoperative @entity1635 was 75.7 degrees (range, 39-130 degrees) in the 22 @entity1 with @entity85 ; 4 @entity1 with thoracic hyperkyphoses averaged 70.5 degrees (range, 46-90 degrees) and 10 @entity1 with lumbar kyphoses averaged 80.5 degrees (range, 42-120 degrees). The instrumentation extended to the sacrum in 4 @entity1 and the pelvis in 9; 10 @entity1 also underwent anterior release and fusion and 7 underwent concomitant spinal cord detethering. At an average follow-up of 4.0 years (2.0-7.7 years; one @entity1 died at 8 months), all @entity1 have fused (with the exception of two @entity1516 ). RESULTS: At last follow-up, deformity measured 32.1 degrees @entity1635 (range, 6-85 degrees), 30.8 degrees @entity1513 (range, 24-35 degrees), and 0.0 degree lumbar @entity1513 (range, 35 degrees @entity1513 to 29 degrees @entity1515 ). Three @entity1 lost some neurologic function after surgery; two recovered within 6 months and one has incomplete recovery. No ambulatory @entity1 lost the ability to walk. Five @entity1 required additional surgical procedures; in three cases, there was instrumentation breakage associated with @entity1516 or unfused spinal segments. CONCLUSIONS: Pedicle screw instrumentation is uniquely suited to the @entity2590 . Compared with historical control subjects, these devices have proven capable of significant correction of both scoliotic and @entity85 . This instrumentation appears particularly useful in preserving @entity1515 in all @entity1 and may preserve @entity11535 in ambulatory @entity2590 @entity1 .

XXXX in @entity2590 . Correction with posterior pedicle screw instrumentation.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1513 :: ('MESH:D007738', 'Disease') :: ['thoracic kyphosis', 'kyphosis'] @entity1417 :: ('MESH:C565217', 'Disease') :: ['deficient posterior elements'] @entity2590 :: ('MESH:D009190', 'Disease') :: ['myelodysplasia', 'deficient myelodysplastic spine'] @entity1635 :: ('MESH:D012600', 'Disease') :: ['scoliosis'] @entity1515 :: ('MESH:D008141', 'Disease') :: ['lordosis', 'lumbar lordosis'] @entity11535 :: ('MESH:D009041', 'Disease') :: ['more lumbar motion'] @entity85 :: ('MESH:D009140', 'Disease') :: ['spinal deformities', 'spinal deformity', 'scoliotic deformities', 'kyphotic deformities'] @entity1516 :: ('MESH:D011542', 'Disease') :: ['lumbosacral pseudarthroses', 'pseudarthrosis']
@entity85 :: (MESH:D009140,Disease) :: ['Spinal deformity']
