PURPOSE: Intractable @entity322 ( @entity322 ) and @entity1142 is a challenging condition to manage in @entity1 . Transanal irrigation (TAI) is a non-operative treatment option. This study presents our experience with TAI with the aim of finding predictive factors of non-compliance. METHODS: This is an outcome and quality of life (QoL) study of a prospectively maintained database of @entity1  <  17  years old commenced on TAI for intractable @entity322 / @entity1142 between 2008 and 2014. Outcome measures were: (1) compliance-classified as non-adopter (use of TAI stopped within 1  month after commencement) or adopter; (2) functional outcome-classified as responder (totally continent or occasional soiling) or non-responder; (3) Rintala score; and (4) QoL score (PedsQL    4.0 Generic Core Scale). Analysis to determine predictive factors was also performed. RESULTS: 42 @entity1 were started on TAI [74  % male, median age of commencement was 7 (3-16) years]. Underlying diagnoses were: idiopathic @entity1142 (62  %), @entity2463 (26  %), @entity1963 (5  %), @entity3570 (5  %) and @entity6675 (2  %). Median follow-up period was 14 (3-78) months. 24  % were non-adopters. 84  % of the adopters responded to treatment. Rintala scores (mean      SD) pre- and post-TAI were 6.7      3.5 and 11.2      4.8, respectively (P  <  0.001). QoL scores pre- and post-TAI were 55.6      24.1 and 65.5      23.7, respectively (P  <  0.001). Median age at which TAI was commenced in the non-adopter and adopter group were 6 (IQR 4.5-8.25) and 8 (IQR 7-12), respectively (P  =  0.008). CONCLUSION: TAI is a safe and effective treatment for intractable @entity1142 / @entity322 in @entity1 . If tolerated, it can significantly improve quality of life. Age and underlying diagnosis are important factors when recommending TAI to @entity1 with intractable @entity322 / @entity1142 .

Transanal irrigation for intractable XXXX and @entity1142 : outcomes, quality of life and predicting non-adopters.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity3570 :: ('MESH:D016135', 'Disease') :: ['spina bifida'] @entity322 :: ('MESH:D014549', 'Disease') :: ['faecal incontinence', 'FI'] @entity1963 :: ('MESH:D006627', 'Disease') :: ['Hirschsprung disease'] @entity2463 :: ('MESH:C537771', 'Disease') :: ['anorectal malformation'] @entity6675 :: ('MESH:D020139', 'Disease') :: ['gastroschisis'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation']
@entity322 :: (MESH:D014549,Disease) :: ['faecal incontinence']
