BACKGROUND/AIMS: The use of major versus limited hepatic resection for @entity14 remains controversial. We evaluated the role of major hepatic resection in managing @entity1 with @entity14 . METHODOLOGY: We performed a retrospective analysis of 102 @entity1 undergoing either major (n = 61) or limited (n = 41) hepatic resection for @entity14 metastases. Major hepatic resection was defined as segmentectomy or more extensive hepatic resection; limited hepatic resection was defined as @entity96 plus a rim of normal parenchyma. The median follow-up period was 94 months. RESULTS: @entity1 undergoing major hepatic resection had larger @entity99 than those undergoing limited hepatic resection (p < 0.001, Fisher's exact test). The cumulative probability of intrahepatic recurrences after major hepatic resection was significantly lower than that after limited hepatic resection (p = 0.010, log-rank test). Major hepatic resection independently reduced the probability of intrahepatic recurrences (p = 0.043, Cox's proportional hazards model). Limited hepatic resection frequently resulted in recurrences within the same segment or the same lobe of the remnant liver. CONCLUSIONS: Major hepatic resection is more effective in reducing the risk of intrahepatic recurrences than limited hepatic resection in @entity1 with resectable @entity14 .

Major hepatic resection reduces the probability of intrahepatic recurrences following resection of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic tumors'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal carcinoma', 'colorectal carcinoma liver metastases'] @entity96 :: ('MESH:D008113', 'Disease') :: ['non-anatomic removal of the liver tumor']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal carcinoma liver metastases']
