AIMS: To investigate the association between @entity5 mortality risk and exposure to @entity16411 in groundwater of a downstream community near a contaminated site. METHODS: Death certificates inclusive for the years 1966-97 were collected from two villages in the vicinity of an electronics factory operated between 1970 and 1992. These two villages were classified into the downstream (exposed) village and the upstream (unexposed) according to groundwater flow direction. Exposure classification was validated by the contaminant levels in 49 residential wells measured with gas chromatography/mass spectrometry. Mortality odds ratios (MORs) for @entity5 were calculated with @entity65 as the reference diseases. Multiple logistic regressions were performed to estimate the effects of exposure and period after adjustment for age. RESULTS: Increased MORs were observed among males for all @entity5 for the periods after 10 years of latency, namely, 1980-89, and 1990-97. Adjusted @entity6253 for @entity96 was 2.57 (95% confidence interval 1.21 to 5.46) with a significant linear trend for the period effect. CONCLUSION: The results suggest a link between exposure to @entity16411 and @entity96 risk. However, the conclusion is limited by lack of individual information on groundwater exposure and potential confounding factors.

Increased mortality odds ratio of XXXX in a community contaminated by @entity16411 in groundwater.

@entity16411 :: ('MESH:D006843', 'Chemical') :: ['chlorinated hydrocarbons'] @entity6253 :: ('4988', 'Gene') :: ['MOR'] @entity96 :: ('MESH:D008113', 'Disease') :: ['male liver cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer, and liver cancer', 'cancer'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular-cerebrovascular diseases']
@entity96 :: (MESH:D008113,Disease) :: ['male liver cancer']
