PURPOSE: To investigate the perioperative and long-term outcomes of endovascular therapy (EVT) for subclavian @entity455 in a large-scale multicenter study. METHODS: The study analyzed the outcomes from a multicenter retrospective registry (SubClavian @entity455 treated with endovascuLar therapy; muLticenter retrOsPective registry: SCALLOP) of 718 consecutive @entity1 with @entity455 who underwent EVT between January 2003 and December 2012 at 37 Japanese cardiovascular centers. Of the 718 @entity1 enrolled in the registry, 162 @entity1 were excluded, leaving 553 @entity1 (mean 70  7 years, range 41-91; 405 @entity1 ) who underwent primary EVT for de novo subclavian @entity455 (560 arms). RESULTS: Procedure success was achieved in 96.8% (100% for stenoses, 91% for total occlusions). The perioperative complication rate was 9.2%. @entity64 was found in 1.8%, with ipsilateral posterior @entity1188 accounting for 0.9%. The 30-day mortality was 0.7%. The mean follow-up was 39  24 months. Primary patency estimates were 90.6%  1.3%, 83.4%  1.8%, and 80.5%  2.2% at 1, 3, and 5 years, respectively. There was no significant difference in primary patency between stenotic and occlusive lesions. Secondary patency estimates were 99.2%  0.4%, 98.2%  0.6%, and 97.7%  0.8% at 1, 3, and 5 years, respectively. The respective overall survival rates were 94.6%  1.0%, 86.8%  1.7%, and 79.0%  2.4%. There were 86 deaths during follow-up, of which half were due to cardiovascular causes. On multivariate analysis, critical hand @entity63 (hazard ratio [HR] 4.6, 95% CI 2.06 to 10.2, p<0.001), @entity66 (HR 1.9, 95% CI 1.14 to 3.06, p=0.01), current smoking (HR 1.8, 95% 1.14 to 2.79, p=0.01), and lesion length (in 1-cm increments; HR 1.02, 95% CI 1.00 to 1.04, p=0.03) were negative independent predictors of primary patency, while IVUS use (HR 0.6, 95% CI 0.30 to 0.96, p=0.04) was a positive predictor of primary patency. CONCLUSION: Primary angioplasty/stenting for subclavian @entity455 afforded acceptable outcomes in terms of perioperative complications and long-term patency.

Perioperative and Long-term Outcomes of Endovascular Treatment for Subclavian XXXX From a Large Multicenter Registry.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['Stroke'] @entity455 :: ('MESH:D014652', 'Disease') :: ['artery disease', 'Artery disease', 'upper extremity artery disease'] @entity66 :: ('MESH:D004194', 'Disease') :: ['cerebrovascular disease'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarction']
@entity455 :: (MESH:D014652,Disease) :: ['Artery Disease']
