INTRODUCTION: Surgery for @entity1358 with @entity5 @entity715 has a high potential morbidity rate, and the current classification system based on proximal @entity5 @entity715 level (TTL) has not been shown to consistently predict outcomes. AIM: To assess the prognostic value of inferior vena cava @entity5 @entity715 volume (IVC-TV) for determining the perioperative complications as well as with survival end points. METHODS: From June 2001 to June 2012, we identified 147 @entity1 who underwent radical nephrectomy with venous thrombi. In total, 66 @entity1 had IVC involvement and available imaging for review. IVC-TV was measured by cross-sectional area and height measurement for each axial slice. Linear, logistic models and Cox proportional hazard was used for analysis. RESULTS: Median IVC-TV was 16.5cm(3), and 18 @entity1 had TTL>= III. In total, 57 Clavien I-V complications were documented in 32 @entity1 including 3 deaths. On multivariate analysis, age>65 years, American Society of Anesthesiologists>3, and IVC-TV>15cm(3) were independent predictors for perioperative complications. Disease progression (PoD) occurred in 78% of @entity1 , and @entity3 (hazard ratio [HR] = 3.33, P<0.01) and non-clear cell histology (HR = 2.98, P = 0.02) were independent predictors of PoD. Median time to @entity204 was 16 months (interquartile range: 5.2-42.9). On Cox regression analysis, @entity3 , non-clear cell histology, IVC-TV>15cm(3), and TTL III/IV were significantly associated with overall survival. As a preoperative variable, IVC-TV>15cm(3) was shown to be an independent predictor of PoD (HR = 2.3, P = 0.01) and overall survival (HR = 2.21, P = 0.03). CONCLUSION: IVC-TV has value as a prognostic indicator, which is superior to TTL in the setting of @entity1358 with @entity1211 .

@entity5 XXXX volume influences outcomes in @entity1358 with @entity1211 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1358 :: ('MESH:D002292', 'Disease') :: ['renal cell carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic disease'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['IVC venous thrombus'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity715 :: (MESH:D013927,Disease) :: ['thrombus']
