BACKGROUND: This study was designed to assess the epidemiology, characteristics, and outcome of @entity299 ( @entity299 ) in Finland. METHODS AND RESULTS: We identified in retrospect all adult (>18 years of age) @entity1 diagnosed with histologically confirmed @entity299 in Finland between 1988 and 2012. A total of 110 @entity1 (71 @entity1 ) 51  9 years of age (mean  SD) were found and followed up for outcome events to the end of 2013. The annual detection rate of @entity299 increased >20-fold during the 25-year period, reaching 0.31 in 1*10(5) adults between 2008 and 2012. The 2012 prevalence of @entity299 was 2.2 in 1*10(5). Nearly two thirds of @entity1 had clinically isolated @entity299 . Altogether, 102 of the 110 @entity1 received immunosuppressive therapy, and 56 received an intracardiac defibrillator. Left ventricular function was impaired (ejection fraction <50%) in 65 @entity1 (59%) at diagnosis and showed no overall change over 12 months of @entity479 therapy. During follow-up (median, 6.6 years), 10 @entity1 died of a cardiac cause, 11 @entity1 underwent transplantation, and another 11 @entity1 suffered an @entity1164 . The Kaplan-Meier estimates for 1-, 5-, and 10-year transplantation-free cardiac survival were 97%, 90%, and 83%, respectively. @entity712 at presentation predicted poor outcome (log-rank P=0.0001) with a 10-year transplantation-free cardiac survival of only 53%. CONCLUSIONS: The detection rate of @entity299 has increased markedly in Finland over the last 25 years. With current therapy, the prognosis of @entity299 appears better than generally considered, but @entity1 presenting with @entity712 still have poor long-term outcome.

XXXX : epidemiology, characteristics, and outcome over 25 years in a nationwide study.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity1164 :: ('MESH:D016757', 'Disease') :: ['aborted sudden cardiac death'] @entity712 :: ('MESH:D006333', 'Disease') :: ['Heart failure', 'heart failure'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac sarcoidosis', 'CS'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity299 :: (MESH:D006331,Disease) :: ['Cardiac sarcoidosis']
