PURPOSE: The purpose of this study was to analyze cartilage @entity528 in knees after total medial meniscectomy, transplantation of fresh-frozen meniscus allograft, and Achilles tendon allograft. TYPE OF STUDY: Experimental study. METHODS: We have studied the articular cartilage in the medial compartment of the left knees in 32 @entity742 aged 5 to 6 months, with 8 animals in each group. The study was performed after meniscectomy (group I), transplantation of fresh-frozen meniscus allograft (group II), use of fresh-frozen Achilles tendon allograft (group III), and in a control group (group IV). For the histologic study, all samples were stained with Masson's trichrome and @entity18998 . Mankin's score was applied to grade the histologic damage to the articular cartilage. RESULTS: The group with the greatest number of degenerative changes was group III, followed by groups I and II. The percentage of thickness of cartilage detected by @entity18998 -O stain was found to be significantly different in both tibia and femur between the control group and the other 3 groups, but not among groups I, II, and III. The immunoreactivity of the articular surfaces in tibia and femur showed notable differences in all the groups. Collagen X was present in the degenerative @entity1184 chondrocytes in the damaged articular surfaces. CONCLUSIONS: Meniscal replacement with meniscal and Achilles tendon allografts provides partial protection against @entity16 after a meniscectomy.

Articular cartilage @entity528 after frozen meniscus and Achilles tendon allograft transplantation: experimental study in XXXX .

@entity742 :: ('9940', 'Species') :: ['sheep'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['hypertrophic'] @entity16 :: ('MESH:D009422', 'Disease') :: ['articular damage'] @entity18998 :: ('MESH:C009195', 'Chemical') :: ['Safranine', 'Safranine-O'] @entity528 :: ('MESH:D009410', 'Disease') :: ['degeneration']
@entity742 :: (9940,Species) :: ['sheep']
