BACKGROUND: Current literature reports improvement in kidney function in @entity28 @entity1 after bariatric surgery in non-Asian centers. It is unclear how kidney function is affected by postoperative body composition changes in @entity28 Asian @entity1 . OBJECTIVES: To evaluate kidney function and its relationship to body composition in a multiethnic Asian population after bariatric surgery. SETTING: This study was performed in a university hospital. METHODS: Data of 68 @entity28 @entity1 who were followed for 1 year after surgery were retrieved from our university hospital clinical care database. Body composition was obtained by bioimpedance analysis. Kidney function was calculated as glomerular filtration rate (GFR) using the following formulas: (1) @entity740 Epidemiology Collaboration (CKD-EPI) (estimated GFR [eGFR], mL/ @entity1009 .73 m(2)); (2) absolute GFR (aGFR, mL/min); and (3) lean weight-adjusted Cockcroft-Gault @entity1011 clearance (CG-LBW, mL/min). @entity1 were further examined by 2 subgroups: eGFR<90 and>90 mL/ @entity1009 .73 m(2). RESULTS: One year after surgery, body mass index (BMI) declined from 41.9  5.7 to 29.6  4.2 kg/m(2) (P<.001), body surface area (BSA) decreased from 2.15  0.23 to 1.86  0.18 m(2) (P<.001), and fat mass (FM) reduced from 45.8  9.4 to 25.6  10.5 kg (P<.001). There were significant differences in percentage excess @entity353 (%EWL) among Chinese, Malays, Indians, and other ethnicities. Similar results were found with percentage fat mass loss (%FML). Changes in aGFR were associated with reductions in FM (P = .010), BSA (P = .049), and %EWL (P<.001). In the eGFR>90 subgroup, eGFR decreased from 143  22 to 122  19 mL/ @entity1009 .73 m(2). Conversely, in the eGFR<90 subgroup, eGFR had a trend of improvement from 69 to 79 mL/ @entity1009 .73 m(2). CONCLUSION: Changes in eGFR after bariatric surgery in the @entity28 Asian @entity1 are strongly associated with reduction in FM, BSA, and %EWL. More work is required to investigate if certain ethnicities have better postoperative renal profiles.

Effect of XXXX after bariatric surgery on kidney function in a multiethnic Asian population.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity1009 :: ('966', 'Gene') :: ['min/1'] @entity740 :: ('MESH:D051436', 'Disease') :: ['Chronic Kidney Disease'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity353 :: (MESH:D015431,Disease) :: ['weight loss']
