UNASSIGNED: Italian national guidelines recommend regional implementation of organized screening programmes for @entity5 . As we have been doing since 1998, we collected aggregated tables of data from Italian organized cervical screening programmes in order to centrally compute process indicators. Data on @entity1 invited during 2011 and 2012 and screened up to April of the subsequent year were considered. In 2012, the target population of Italian organized screening programmes included 14,497,207 @entity1 , corresponding to 87.3% of Italian @entity1 aged 25-64 years. Compliance to invitation was 41.2%in 2011 and 40.8%in 2012, with a strong decreasing North-South trend. However, it should be considered that many @entity1 are screened outside any organized programmes. In 2012, of the @entity1 screened, 3.5% were referred for repeat cytology and 71.1% of them complied; 2.4% of screened @entity1 were referred to colposcopy. Compliance with colposcopy referral was 85.3%among @entity1 referred because of ASC-US or more severe cytology and 90.4% among those referred because of @entity2784 or more severe cytology. The positive predictive value ( @entity2286 ) of referral because of ASC-US or more severe cytology for CIN2 or more severe histology was 16.9%. The unadjusted detection rate of CIN2 or more severe histology was 3.4 per 1,000 screened @entity1 (3.6 standardized on the Italian population, truncated 25-64). CIN2 or more severe histology was detected in 64.6% of colposcopies classified as grade 2 or higher. Of all colposcopies during which a CIN2 or more severe histology was obtained, 33.6% were classified as grade 2 or higher. Follow-up only was recommended to 81.7% of @entity1 with CIN1. Excision by radio-frequency device was the most common treatment for @entity1 with CIN2 (52.8%) and CIN3 (57.0%). However 0.4% of all CIN2 and 2.3% of all CIN3 had hysterectomy.

Extension of organized XXXX screening programmes in Italy and their process indicators, 2011-2012 activity.

@entity5 :: ('MESH:D009369', 'Disease') :: ['cervical cancer'] @entity1 :: ('9606', 'Species') :: ['women'] @entity2784 :: ('MESH:D065310', 'Disease') :: ['HSIL'] @entity2286 :: ('12211', 'Species') :: ['PPV']
@entity5 :: (MESH:D009369,Disease) :: ['cervical cancer']
