@entity4542 (CSLs) of the breast are benign radiologic and histologic entities. With the introduction of population-based screening programs, their incidence has increased to 0.03% to 0.09% of all core needle biopsies (CNBs). They can pose diagnostic difficulty because their radiologic and histologic appearances mimic @entity189 . We retrospectively searched for and reviewed all cases of RS/ @entity10718 diagnosed on image-guided CNB from January 1, 1994, to August 31, 2013, at a single institution. We also assessed the pathologic reports from excisional biopsies to identify cases upstaged to atypia or @entity5 . After exclusions, 100 CNBs were identified from 97 @entity1 , which showed RS/ @entity10718 without concomitant atypia. Mean age of the @entity1 was 52.9 years. Thirty-five @entity1 (38/100 CNBs, 38%) had follow-up excision. The median size of the excised RS/CSLs was 1.2 cm; 69% were larger than 1.0 cm. Almost all excised cases (92%) showed radiologic and pathologic concordance, and 79% were designated as suspicious for @entity5 (Breast Imaging Reporting and Data System level 4). The most common findings of 38 follow-up excisional biopsies were residual RS (22 [58%]), @entity1137 (5 [13%]), and no residual lesion (5 [13%]). Eleven excisional biopsies (29%) were upstaged to @entity2735 or to @entity1373 . Follow-up excisional biopsy is warranted for RS/CSLs, specifically those larger than 1.0 cm with worrisome radiographic findings or with radiologic and pathologic discordance. Approximately 29% of cases were upstaged to in situ or invasive @entity189 or other high-risk lesions in our study.

XXXX : a clinicopathologic correlation study from a single institution.

@entity1 :: ('9606', 'Species') :: ['women'] @entity1137 :: ('MESH:D018275', 'Disease') :: ['atypical lobular hyperplasia'] @entity2735 :: ('MESH:D002278', 'Disease') :: ['invasive or in situ carcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancy', 'neoplasm'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['atypical hyperplasia'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas', 'carcinoma'] @entity10718 :: ('1444', 'Gene') :: ['CSL'] @entity4542 :: ('MESH:D020425', 'Disease') :: ['Radial scars (RSs) or complex sclerosing lesions']
@entity4542 :: (MESH:D020425,Disease) :: ['Radial scar/complex sclerosing lesions']
