OBJECTIVE: To aims of this study was to assess and compare the efficacy of @entity865 and surgery in the treatment of severe @entity6250 . DESIGN: Prospective 12-month study of 180 consecutive @entity1 with severe chronic @entity6250 . METHODS: PTA was used as first line therapy whenever possible and appropriate. Surgical revascularisation, primary amputation and conservative therapy were used in eh remaining @entity1 . @entity1 survival and limb salvage were derived using life table analysis. RESULTS: Revascularisation was attempted in 135 (75%) @entity1 , with PTA in 82 (46%), surgery in 19 (27%) and a combination of both in four (2%). Overall 12-month survival and limb salvage was 75% and 71%, respectively. Surgery and PTA had significantly higher survival rates (91% and 78%) than primary amputation or conservative therapy (57% and 52%) (p < 0.0001 log rank test). Revascularisation with either surgery or PTA achieved the same limb salvage rate of 76%. CONCLUSION: A large proportion of @entity1 with severe chronic @entity6250 can be managed by PTA. THis management strategy produces a clinically effective outcome at 1-year.

Results of surgery and angioplasty for the treatment of chronic severe XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity6250 :: ('MESH:D038061', 'Disease') :: ['lower limb ischaemia'] @entity865 :: ('CHEBI:61432', 'Chemical') :: ['PTA']
@entity6250 :: (MESH:D038061,Disease) :: ['lower limb ischaemia']
