OBJECT: Applanation tonometry is a noninvasive method of assessing both peripheral and central arterial blood pressure (BP) profiles. In this study the authors examine whether there are differences in these profiles in @entity1 with @entity438 when compared with age-matched controls. METHODS: Carotid artery (CA) and derived aortic BP waveforms were obtained using a pulse wave analysis system. The ratio of the pressure wave amplitude above the systolic shoulder to the total systolic BP (augmentation index [AI]) was recorded. One hundred seventy-three @entity1 with @entity438 (23 unruptured lesions) and 173 healthy control volunteers were examined. For the @entity1 with @entity439 the right and left CA AIs (mean +/- standard deviation) were 125.6 +/- 23.1% and 128.3 +/- 22.1%, respectively. Corresponding values for the control group were 118.4 +/- 22.6% and 119.4 +/- 21.8%. The calculated AI for the ascending aorta was 29.8 +/- 10.5% and 25.6 +/- 12.2% for @entity1 with @entity439 and control volunteers, respectively. Significant asymmetry in CA AI was seen in @entity1 with @entity439 , the left being greater (p = 0.002). No significant differences were seen in mean BP (108 +/- 14 mm Hg in @entity1 with @entity439 compared with 106 +/- 16 mm Hg in controls; p = 0.2). Multivariate analysis excluded the influence of BP and other potential confounding vascular risk factors for increased AI. CONCLUSIONS: Significant differences in AI, both in magnitude and symmetry, were identified in @entity1 with @entity438 when compared with matched controls.

The influence of hemodynamic stress factors on intracranial XXXX formation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms'] @entity438 :: ('MESH:D002532', 'Disease') :: ['intracranial aneurysms']
@entity439 :: (MESH:D000783,Disease) :: ['aneurysm']
