Importance: Psoriasis is a risk factor for @entity308 . @entity308 may also trigger or exacerbate @entity1569 . The relationship between @entity1569 and @entity308 , however, remains to be fully explored. Objective: To investigate the association between @entity1569 and @entity308 in the US population. Design, Setting, and @entity1 : Population-based study using @entity1 in the National Health and Nutrition Examination Survey from 2009 through 2012. Main Outcomes and Measures: Diagnosis of @entity308 based on the @entity1 Health Questionnaire-9. Results: We identified 351 (2.8%) cases of @entity1569 and 968 (7.8%) cases of @entity308 among 12   382 US citizens included in our study. Fifty-eight (16.5%) @entity1 with @entity1569 met criteria for a diagnosis of @entity308 . The mean (SD) @entity1 Health Questionnaire-9 score was significantly higher among @entity1 with a history of @entity1569 than those without @entity1569 (4.54 [5.7] vs 3.22 [4.3], P   <   .001). Psoriasis was significantly associated with @entity308 , even after adjustment for sex, age, race, body mass index, physical activity, smoking history, @entity285 use, history of @entity583 ( @entity583 ), history of @entity64 , and history of @entity6 (OR, 2.09 [95% CI, 1.41-3.11], P   <   .001). Interaction term analyses involving @entity1 with a history of both @entity1569 and a cardiovascular event, specifically @entity583 or @entity64 , did not reveal a synergistically increased risk of @entity308 ( @entity1569 and @entity583 : OR, 1.09 [95% CI, 0.28-3.60], P   =   .91; @entity1569 and @entity64 : OR, 0.67 [95% CI, 0.12-3.66], P   =   .63). In adjusted multivariable models, the risk of @entity308 was not significantly different between @entity1 with limited vs extensive @entity1569 (OR, 0.66 [95% CI, 0.18-2.44], P   =   .53). Conclusions and Relevance: Self-reported history of @entity1569 was independently associated with @entity308 as assessed by a validated screening tool, even when controlling for comorbidities. History of cardiovascular event did not modify the risk of @entity308 for @entity1 with @entity1569 . The severity of @entity1569 was unrelated to the risk of @entity308 . Therefore, all @entity1 with @entity1569 , regardless of severity, may be at risk for @entity308 .

Psoriasis and the Risk of XXXX in the US Population: National Health and Nutrition Examination Survey 2009-2012.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'Participants', 'Patient'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression', 'depression', 'major depression'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1569 :: ('MESH:D011565', 'Disease') :: ['psoriasis'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity285 :: ('D000431', 'Chemical') :: ['alcohol']
@entity308 :: (MESH:D003866,Disease) :: ['Depression']
