BACKGROUND: Vascular @entity1642 ( @entity1642 ) has been implied in the pathogenesis of @entity731 and vascular remodeling. Our aim was to calculate @entity1642 after balloon angioplasty and evaluate its predictive value for long-term outcome. METHODS: @entity1642 was calculated proximal to, in, and distal to the lesion after angiographically successful @entity384 and at follow-up with the Hagen-Poiseuille formula ( @entity1642 = 4 microQ/piR3) in 202 @entity1 . Volumetric blood flow (Q) and lumen radius (R) were derived from Doppler scanning velocities and videodensitometric cross-sectional areas. RESULTS: Postprocedural proximal and in-lesion values were higher in vessels that developed @entity256 (n = 72; 1.22 +/- 0.61 N/m2 and 3.61 +/- 2.38 N/m2, respectively) than in those without @entity256 (n = 130, 1.05 +/- 0.51 N/m2 and 2.46 +/- 1.39 N/m2, respectively; P <.05). In-lesion @entity1642 was revealed to be predictive of @entity256 by means of logistic regression analysis (odds ratio [OR] = 1.42, P <.05), whereas @entity1642 of the proximal segment was associated with an increased rate of @entity75 revascularization (OR = 2.33, P <.005). In the multivariate regression model, @entity1642 of the proximal segment was the only independent predictor when entered with known predictors such as diameter stenosis and coronary flow reserve (OR = 2.15, P <.05). CONCLUSIONS: @entity1642 in the lesion after balloon angioplasty is predictive of angiographic @entity256 . Moreover, the proximal value is an independent predictor of @entity75 revascularization. This study opens perspectives for the on-line use of @entity1642 as a combined parameter of anatomy and physiology to assess the necessity of adjunctive therapy after successful @entity384 .

High shear stress after successful balloon angioplasty is associated with XXXX and @entity75 revascularization.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity75 :: ('MESH:D001927', 'Disease') :: ['target lesion'] @entity384 :: ('MESH:D002311', 'Disease') :: ['balloon dilatation'] @entity256 :: ('MESH:D023903', 'Disease') :: ['restenosis'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity1642 :: ('MESH:D015775', 'Disease') :: ['WSS', 'wall shear stress']
@entity256 :: (MESH:D023903,Disease) :: ['restenosis']
