Fifty-five primary invasive @entity420 of the cervix, presenting over a 20-year period, were retrospectively studied with particular reference to clinical and pathologic prognostic indicators. Mean age at presentation was 54.5 years (range 27-91), with an age distribution showing two incidence peaks of equal size in the 31-35 and 61-65 groups, respectively. Twenty-four @entity1 died of the disease and the remaining @entity1 were followed up for a mean of 4.9 years (range 1-17). The results were analyzed using a Cox's proportional hazards survival model. The independent good prognostic indicators were @entity5 stage (P < 0.001). and young @entity1 age (P < 0.001) at presentation. The presence within the @entity5 of numerous intraepithelial lymphocytes and the concomitant occurrence of background in situ @entity189 were also good prognostic indicators, although these did not operate independently of stage and age. @entity5 subtype and grade of @entity5 differentiation were not significant prognostic factors. Treatment did not have a significant independent effect on survival. No definite conclusions could be drawn about the effect of oral contraceptives on the disease process.

Primary XXXX . A clinicopathologic study of prognostic variables in 55 cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Histologic tumor', 'early tumor']
@entity420 :: (MESH:D000230,Disease) :: ['adenocarcinoma of the cervix']
