STUDY OBJECTIVE: The aim of this study was to compare the frequency of intraoperative @entity741 in lower extremity vascular surgery with general anesthesia vs regional anesthesia via @entity2096 . DESIGN: This is a prospective, randomized study. SETTING: This study was set at an academic medical center. @entity1 : The study included 50 @entity1 scheduled for elective lower extremity vascular surgery. INTERVENTIONS: @entity1 in group 1 received balanced general anesthesia, whereas @entity1 in group 2 received @entity2096 with 40 mL of 0.375% @entity1341 . Monitoring included a radial artery catheter and multilead, dual-channel electrocardiogram with computerized ST-segment analysis. Blood pressure and heart rate variations were maintained within 10% of preoperative values by adjusting anesthetic depth, fluid replacement, and vasoactive drug dosages. MEASUREMENTS AND MAIN RESULTS: An ST-segment @entity308 of at least 1 mm or elevation of at least 2 mm lasting for more than 1 minute was considered a significant episode of @entity741 . Intraoperative hemodynamic data and the frequency of significant ST-segment change episodes were recorded. The number of @entity1 with @entity63 episodes and the total number of these episodes were lower in group 2 than in group 1 (1 @entity1 vs 7 @entity1 , P = 0.02; and 2 vs 14 episodes, P = 0.04). No significant difference was found between groups 1 and 2 regarding systolic or diastolic arterial pressures, or heart rate. CONCLUSION: Compared with general anesthesia, @entity2096 reduce the frequency of intraoperative @entity741 in @entity1 undergoing lower extremity vascular surgery.

Intraoperative XXXX in peripheral vascular surgery: general anesthesia vs @entity2096 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'PATIENTS'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity1341 :: ('MESH:D002045', 'Chemical') :: ['bupivacaine'] @entity741 :: ('MESH:D017202', 'Disease') :: ['myocardial ischemia'] @entity2096 :: ('MESH:D020428', 'Disease') :: ['combined sciatic and femoral nerve blocks']
@entity741 :: (MESH:D017202,Disease) :: ['myocardial ischemia']
