@entity1653 exhibit a broad spectrum of differentiation potency corresponding to different histological subtypes. The separate secretory or lipomatous transformation of meningothelial cells is uncommonly encountered in @entity1653 classified into distinct secretory or lipomatous variants. The coexistence of these two different histological subtypes is extremely rare. We report an exceptional case of @entity1653 associated with extensive lipomatous component in a 58-year-old @entity1 . CT scan and MRI of the brain showed a well-defined @entity5 mass in the right temporal lobe with areas of adipose tissue and extensive surrounding @entity2657 . Microscopically, the @entity5 was composed of two components: whorls of meningothelial cells with numerous PAS-positive hyaline inclusions (pseudopsammoma bodies) and numerous mature adipocyte-like cells. The presence of neutral fat was confirmed by oil-red-O staining. The hyaline inclusions and @entity5 cells surrounding them showed strong immunoreactivity for EMA and @entity787 . Ultrastructural findings confirmed both secretory and lipomatous differentiation of @entity5 cells. The majority of lipidized neoplastic cells shared the features of meningothelial cells and adipocytes. Our result supports the opinion that lipomatous component ought to be considered as an advanced lipidization of neoplastic meningothelial cells rather than true metaplastic transformation of meningothelial cells into mature fat tissue. The present case of @entity1653 demonstrates a unique coexistence of secretory and lipomatous meningothelial components, reflecting the multipotency of phenotypic transformation of primary meningothelial cells.

XXXX with the unique coexistence of secretory and lipomatous components: a case report with immunohistochemical and ultrastructural study.

@entity1 :: ('9606', 'Species') :: ['woman'] @entity2657 :: ('MESH:D001929', 'Disease') :: ['brain edema'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity787 :: ('1084', 'Gene') :: ['CEA'] @entity1653 :: ('MESH:D008579', 'Disease') :: ['Meningiomas', 'meningioma', 'secretory meningioma', 'meningiomas']
@entity1653 :: (MESH:D008579,Disease) :: ['Meningioma']
