BACKGROUND: @entity406 (FA) is well documented as a cause of @entity7446 . Recently, attention has been paid to FA as an allergen and a pollutant that enhances allergic sensitization. We have investigated the prevalence of FA-specific IgE in asthmatic @entity1 and the correlation between IgE sensitization to FA and the severity of @entity565 . METHODS: One hundred and fifty-five @entity1 were investigated, 122 of them asthmatic and 33 nonallergic. Specific IgE against FA was measured by CAP RAST. In addition, the @entity1 answered a questionnaire, containing questions on clinical features of their @entity565 , their living conditions, and symptoms of @entity146 . RESULTS: Of all the subjects assessed, FA-specific IgE was detected in only two asthmatics, and their IgE levels of FA were low (0.42 and 0.46 UA/ml). One of the two @entity1 with FA-specific IgE had severe @entity565 and frequent symptoms of @entity146 , but the other had mild @entity565 and only rare symptoms of @entity146 . CONCLUSIONS: The prevalence of IgE sensitization to FA appears very low in Japanese @entity1 , whether or not they have @entity565 . Therefore, it appears likely that FA is not one of the major allergens causing childhood @entity565 .

The prevalence of IgE sensitization to XXXX in asthmatic @entity1 .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity146 :: ('MESH:D001523', 'Disease') :: ['mucosal irritation'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma'] @entity406 :: ('MESH:D005557', 'Chemical') :: ['Formaldehyde'] @entity7446 :: ('MESH:D059366', 'Disease') :: ['occupational asthma']
@entity406 :: (MESH:D005557,Chemical) :: ['formaldehyde']
