INTRODUCTION: Surgical options for symptomatic delayed @entity356 emptying include @entity356 stimulator implantation, subtotal gastrectomy, and pyloroplasty. Pyloroplasty has been shown to improve @entity356 emptying yet is seldom described as a primary treatment for @entity7623 . We present a single-institution experience of @entity9353 ( @entity9353 ) as treatment for @entity7623 . METHODS AND PROCEDURES: A prospective foregut surgery database was queried for @entity9353 over a 5-year period. Charts were reviewed for indications, complications, symptom score, and outcomes. Gastroparesis was defined by (1) abnormal @entity356 emptying study, (2) endoscopic visualization of retained food after prolonged NPO status, or (3) clinical symptoms suspicious of @entity128 following complex re-operative foregut surgery. Results were analyzed using a paired T test and single-factor ANOVA. RESULTS: One hundred and seventy-seven @entity9353 @entity1 were identified and reviewed. One hundred and five had a concurrent fundoplication for objective reflux. There were no intraoperative complications or conversions to laparotomy. Overall morbidity rate was 6.8  % with four return to OR and two confirmed leaks (1.1  % leak rate). Average length of stay was 3.5  days, and readmission rate was 7  %. Eighty-six percent had improvement in GES with normalization in 77  %. Gastric emptying half-time decreased from 175      94 to 91      45  min. Nineteen @entity1 (10.7  %) had subsequent surgical interventions: @entity356 stimulator implantation (12), feeding @entity5274 (6), or subtotal gastrectomy (4). Symptom severity scores for @entity390 , @entity391 , bloating, @entity490 , and early satiety decreased significantly at 3  months. CONCLUSION: Laparoscopic pyloroplasty improves or normalizes @entity356 emptying in nearly 90  % of @entity7623 @entity1 with very low morbidity. It significantly improves symptoms of @entity390 , @entity391 , bloating, and @entity490 . Some @entity1 may go on to another surgical treatment for GP, but it remains a safe and less invasive alternative to a subtotal gastrectomy in these clinically challenging @entity1 .

Laparoscopic pyloroplasty is a safe and effective first-line surgical therapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity128 :: ('MESH:D020209', 'Disease') :: ['vagal nerve injury'] @entity5274 :: ('MESH:D005184', 'Disease') :: ['jejunostomy and/or gastrostomy tube'] @entity9353 :: ('MESH:D008882', 'Disease') :: ['LP', 'laparoscopic Heineke-Mikulicz pyloroplasty'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity7623 :: ('MESH:D018589', 'Disease') :: ['gastroparesis'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric']
@entity7623 :: (MESH:D018589,Disease) :: ['refractory gastroparesis']
