SETTING: Thirteen @entity284 maintenance treatment (MMT) clinics across Yunnan, the province with the highest @entity1 @entity465 virus (HIV) burden in China. OBJECTIVES: To determine, among @entity645 -negative @entity1 on MMT, the proportion lost to follow-up (defined as those who missed the 6-monthly follow-up examination), factors associated with loss to follow-up (LFU), @entity645 seroconversion rate and factors associated with seroconversion. DESIGN: Prospective cohort study from October 2008 to April 2011. All @entity1 were administered a pre-tested structured questionnaire to capture associated factors and offered @entity645 testing every 6 months.   (2) test and log-binomial regression were used for data analysis. RESULTS: Of 1146 @entity1 , 541 (47%) were lost to follow-up in 2.5 years. Factors associated with higher LFU proportion include <6 months of previous MMT, inconvenient location of the MMT clinic and average @entity284 dose    60 mg/day, with adjusted relative risks (RRs) of respectively 1.4 (95%CI 1.2-1.5), 1.2 (95%CI 1.0-1.4) and 1.1 (95%CI 1.0-1.3). The overall @entity645 seroconversion rate was 6.6 (95%CI 3.7-11.0) per 1000 @entity1 -years. Not living with a partner contributed to higher @entity645 rates, with an adjusted RR of 3.6 (95%CI 1.0-12.8). CONCLUSION: The retention rate of MMT @entity1 in Yunnan was not satisfactory. Decentralising service delivery in the community and making directly observed treatment more convenient has the potential to improve retention.

Retention and @entity645 seroconversion among drug users on XXXX maintenance treatment in Yunnan, China.

@entity1 :: ('9606', 'Species') :: ['participants', 'human', 'person'] @entity465 :: ('MESH:D007153', 'Disease') :: ['immunodeficiency'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity284 :: ('MESH:D008691', 'Chemical') :: ['methadone']
@entity284 :: (MESH:D008691,Chemical) :: ['methadone']
