Conceptus-uterine communication is established during trophoblastic elongation when the conceptus synthesizes and releases @entity172 , the maternal recognition signal in the @entity1707 . @entity4590 ( @entity16318 ) is a differentially expressed gene during rapid trophoblastic elongation in the @entity1707 . The current investigation determined conceptus and endometrial changes in gene expression for @entity16318 , IL-1 receptor antagonist (IL-1Rant), IL-1 receptor type 1 (IL-1RT1), and @entity34602 ( @entity34602 ) in developing peri- and postimplantation conceptuses as well as uterine endometrium collected from cyclic and pregnant gilts. Conceptus @entity16318 gene expression was enhanced during the period of rapid trophoblastic elongation compared with earlier spherical conceptuses, followed by a dramatic decrease in elongated Day 15 conceptuses. IL-1RT1 and @entity34602 gene expression was greater in Day 12 and 15 filamentous conceptuses compared with earlier morphologies while IL-1Rant gene expression was unchanged by conceptus development. The uterine lumenal content of @entity16318 increased during the process of trophoblastic elongation on Day 12. Uterine @entity16318 content declined on Day 15, reaching a nadir by Day 18 of pregnancy. @entity16318 gene expression in porcine conceptuses was temporally associated with an increase in endometrial IL-1RT1 and @entity34602 gene expression in pregnant gilts. Endometrial @entity16318 and IL-1Rant gene expression were lowest during Days 10-15 of the estrous cycle and pregnancy. The temporal expression of @entity16318 during conceptus development and the initiation of conceptus-uterine communication suggests conceptus @entity16318 synthesis plays an important role in porcine conceptus elongation and the establishment of pregnancy in the @entity1707 .

Characterization of the XXXX system during porcine trophoblastic elongation and early placental attachment.

@entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity1707 :: ('9823', 'Species') :: ['pig'] @entity34602 :: ('100628318', 'Gene') :: ['IL-1RAP', 'IL-1 receptor accessory protein'] @entity16318 :: ('397122(Tax:9823)', 'Gene') :: ['IL-1beta'] @entity4590 :: ('396565(Tax:9823)', 'Gene') :: ['Interleukin-1beta']
@entity4590 :: (396565(Tax:9823),Gene) :: ['interleukin-1beta']
