Sutures may cause endothelial trauma and occlusion. The vascular clip system (VCS) clip applier may minimize endothelial injury. Fourteen carotid arteries of nine adult @entity95 were transected and re-anastomosed with either #7-0 @entity7502 (Group I, n=8) or VCS clips (Group II, n=6). The animals were sacrificed at 1, 3, 8, 14, and 30 days postoperatively. The operation time and @entity548 amount were checked for each @entity254 . Carotid angiograms, photography, H_E staining and @entity4653 ( @entity4653 ) were performed. Fibrin and @entity715 , inflammatory cell infiltration, endothelial disruption, luminal distortion, @entity82 , and wall thickening were compared. The luminal diameter was greater in group II. There were minimal differences in @entity715 , wall thickening and @entity82 between the two groups. However, fibrin, inflammatory cell infiltration, multinucleated giant cell formation, endothelial disruption, and luminal distortion were greater in group I. On @entity4653 , group I showed trans-mural penetration. In contrast, group II showed suture margin eversion and no transmural penetration. @entity850 was greater in group I than in group II on carotid angiogram. The operation time was shorter in group II than in group I, i.e. 5+/-1.4 min vs. 11+/-3.8 min, respectively. The current data showed similar or superior results with VCS clips in comparison to conventional suturing with @entity7502 .

XXXX of vessels less than 2 mm with the vascular clip system clip applier.

@entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity7502 :: ('MESH:D011126', 'Chemical') :: ['polypropylene'] @entity95 :: ('9986', 'Species') :: ['rabbits'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus', 'thrombosis'] @entity850 :: ('MESH:D003251', 'Disease') :: ['Stenosis'] @entity4653 :: ('MESH:D004401', 'Disease') :: ['SEM', 'scanning electron microscopy']
@entity254 :: (MESH:C563598,Disease) :: ['Anastomosis']
