A 10-year-old African-American female was evaluated for asymptomatic @entity644 . Initial investigation did not reveal the etiology of her @entity8 . She subsequently underwent a percutaneous renal biopsy, which was consistent with fibrillary @entity8 . This condition is rare in @entity1 and is identified histologically by a solid, randomly arranged, @entity10543 -like fibrillar structure with a diameter of about 18-22 nm. It is a diagnosis of exclusion, the clinical presentation of which can be quite varied. @entity1 usually present with @entity1985 . There is no effective therapy for this condition. Therapy with @entity230 , cytotoxic agents, and plasmapheresis does not confer any real benefit in stabilizing or improving renal function. However, @entity1289 inhibitors can decrease the @entity644 . @entity454 is known to occur in 50% of @entity1 within 4 years of diagnosis. The nephrotic-range @entity644 in our @entity1 significantly decreased during a 4-year follow-up without any therapy, while maintaining normal renal function.

XXXX in a 10-year-old female.

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'Children', 'patient'] @entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity8 :: ('MESH:D007674', 'Disease') :: ['glomerulopathy', 'renal disease'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity1289 :: ('1636', 'Gene') :: ['angiotensin converting enzyme'] @entity10543 :: ('MESH:D017772', 'Disease') :: ['amyloid'] @entity1985 :: ('MESH:D009404', 'Disease') :: ['nephrotic syndrome'] @entity454 :: ('MESH:D007676', 'Disease') :: ['End-stage renal disease']
@entity8 :: (MESH:D007674,Disease) :: ['Fibrillary glomerulopathy']
