OBJECTIVE: To investigate changes in whole-body magnetic resonance imaging (WBMRI) inflammatory and structural lesions in most joints and entheses in @entity1 with @entity309 ( @entity309 ) treated with adalimumab. METHODS: WBMRI was obtained at weeks 0, 6, 16, and 52 in a 52  week follow-up study of 37 @entity309 @entity1 starting treatment with adalimumab. Readability and reliability of WBMRI were investigated for 76 @entity1897 , 23 discovertebral units, the @entity2720 , and 33 entheses. Changes in WBMRI joint and entheses counts were investigated. RESULTS: The readability of peripheral and axial joints was 82-100%, being less for elbows and small joints of the feet. For entheses, 72-100% were readable, except for entheses at the anterior chest wall, elbow, knee, and @entity1411 . The intrareader agreement was high for @entity236 ( @entity236 ), @entity79 (80-100%), and @entity4932 (77-100%), and slightly lower for @entity603 and soft tissue inflammation (50-100%). All @entity603 , @entity236 , and soft tissue inflammation counts decreased numerically during treatment. The 26-joint @entity603 WBMRI count decreased significantly during the first 16  weeks for @entity1 with a good European League Against @entity627 (EULAR) response (from median 6 to 4, p  <  0.05), but not for @entity1 with a moderate or no EULAR response. There were no overall changes in structural lesions. CONCLUSIONS: WBMRI allows simultaneous monitoring of most axial and @entity1897 and entheses in @entity309 @entity1 and can visualize a decrease in inflammatory counts during treatment. This first WBMRI follow-up study of @entity1 with @entity309 encourages further investigation of the usefulness of WBMRI in @entity309 .

Monitoring total-body inflammation and damage in joints and entheses: the first follow-up study of whole-body magnetic resonance imaging in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity627 :: ('MESH:D012216', 'Disease') :: ['Rheumatism'] @entity603 :: ('MESH:D013585', 'Disease') :: ['synovitis'] @entity4932 :: ('MESH:D001171', 'Disease') :: ['enthesitis'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral joints'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone erosion'] @entity2720 :: ('MESH:D007592', 'Disease') :: ['sacroiliac joints'] @entity236 :: ('MESH:D001855', 'Disease') :: ['bone marrow oedema', 'BMO'] @entity1411 :: ('MESH:D016523', 'Disease') :: ['plantar fascia'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis', 'RA']
@entity309 :: (MESH:D001172,Disease) :: ['rheumatoid arthritis']
