We sought to determine the effect of prenatal diagnosis of @entity299 , specifically critical left @entity299 , on postnatal morbidity and mortality. Several studies have found no significant improvement in mortality in @entity1 with prenatally detected @entity299 compared to @entity1 diagnosed postnatally. Few reports have focused on the specific effects of prenatal diagnosis on the perinatal course. All newborns with LHO seen between July 1993 and July 1996 were identified and divided into two groups based on prenatal vs. postnatal diagnosis. Hospital records were reviewed for demographic and outcome variables. The outcome variables included degree of @entity520 , @entity1344 , noncardiac organ dysfunction, delayed surgical intervention, and surgical mortality. Twenty-three fetuses were diagnosed with LHO lesions. Postnatally, 45 newborns presented with @entity4297 . Prenatal diagnosis resulted in avoidance of hemodynamic compromise, reduced organ dysfunction, and reduced surgical delays. There was no significant difference in surgical mortality. Prenatal diagnosis significantly decreases postnatal morbidity in @entity1 with LHO lesions. Although surgical results are similar, the reduced morbidity decreases surgical delays and potentially may impact on neurodevelopmental outcomes.

Effect of prenatal diagnosis of critical left XXXX on perinatal morbidity and mortality.

@entity1 :: ('9606', 'Species') :: ['infants'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart obstructive (LHO) lesions', 'heart disease', 'congenital heart disease'] @entity520 :: ('MESH:D000138', 'Disease') :: ['metabolic acidosis'] @entity1344 :: ('MESH:D043171', 'Disease') :: ['hemodynamic instability'] @entity4297 :: ('MESH:D006330', 'Disease') :: ['LHO anomalies']
@entity299 :: (MESH:D006331,Disease) :: ['heart obstruction']
