UNASSIGNED: Because @entity2 is the most common cause of @entity5 death among both @entity1 and @entity1 , focused efforts are necessary to identify and develop biomarkers that aid in the detection and treatment of this serious disease. Recent research has been aimed at understanding the roles of microRNAs (miRNAs) in tumorigenesis and their utility as @entity5 biomarkers. Here, @entity10017 was investigated as a potential serum biomarker for @entity1149 ( @entity1149 ). The relative expression level of @entity10017 was detected by real-time PCR in the sera of 80 @entity1149 @entity1 ; sera were also collected from 60 healthy @entity1 as a control. The most suitable cut-off value and the prognostic value of serum @entity10017 levels were analyzed using a receiver-operating curve. The relative serum @entity10017 level in @entity1149 @entity1 was significantly higher than that in healthy @entity1 (P<0.05). For relative @entity10017 expression, the area under the ROC curve was 0.812 (95% CI: 0.736-0.888) with a sensitivity of 73.8% and a specificity of 71.7%, based on a cut-off value of 1.22. @entity1149 @entity1 were divided into two groups based on @entity10017 expression; those with higher relative expression (>= 1.22) had significantly lower survival time than those in the lower expression group (P<0.05). Further, serum @entity10017 level and survival time were negatively correlated in @entity1149 @entity1 (P<0.05). Thus, @entity10017 may be useful as a diagnostic and prognostic indicator of @entity1149 .

Serum XXXX level: a potential diagnostic and prognostic biomarker for @entity1149 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'people', 'men'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small cell lung cancer'] @entity10017 :: ('406991', 'Gene') :: ['miR-21']
@entity10017 :: (406991,Gene) :: ['miR-21']
