BACKGROUND: Fatigue is one of the most commonly reported symptoms in primary care and perceived by older @entity1 as an overwhelming and distressing experience that restricts their activity and social participation. Self-reported @entity1295 is complex and multifactorial, with relatively little known about the causes and impacts among older @entity1 . This study tested the association between @entity1295 and objectively measured physical activity in a large cohort of older adults and identified factors that may explain this association. METHODS: Using cross-sectional data from 980 community-living 70- to 77-year-olds, the associations between self-reported @entity1295 and four physical activity outcomes derived from an accelerometer-based activity monitor were tested. Attenuating effects on the association of age, gender, body mass index (BMI), physical condition, comorbidity, @entity308 , and sleep quality were evaluated. RESULTS: Nine percent of the sample reported being fatigued. Fatigued individuals had 1,150 fewer steps/day, 9 minutes/day less of moderate-vigorous activity, 12 minutes/day less of daily activity, and 15% fewer counts/minute, when compared with those not fatigued. BMI, physical condition, and comorbidity attenuated the association, and final regression models including these variables explained most (56%-72%) of the association between @entity1295 and activity. CONCLUSIONS: Fatigue was associated with clinically important reductions in daily physical activity levels of older @entity1 . The findings show BMI, physical condition (in particular @entity410 ), and comorbidity to be important factors in explaining the @entity1295 -physical activity association. Modification of these factors may facilitate increases in daily activity levels by lessening @entity1295 .

Fatigue May Contribute to Reduced Physical Activity Among Older XXXX : An Observational Study.

@entity1 :: ('9606', 'Species') :: ['people'] @entity410 :: ('MESH:D012640', 'Disease') :: ['cardiorespiratory fitness'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue']
@entity1 :: (9606,Species) :: ['People']
