OBJECTIVE: To evaluate factors that influence @entity2704 after outpatient infusion or inpatient treatment for intractable @entity2704 . BACKGROUND: Recurrence of @entity2704 after acute treatment in an infusion center or an inpatient setting is not well documented in @entity1 and adolescents. Given the multifactorial pathogenesis of @entity2704 , multiple factors may influence @entity2704 . It has been reported that treatment with @entity230 may reduce the risk of @entity2704 . The efficacy of @entity230 as a therapeutic adjunct has not been established. Studies in the adult population have yielded conflicting results. METHODS: This study is a retrospective chart review of @entity1 presenting for treatment of an intractable @entity2704 to the outpatient infusion unit or inpatient unit at Cincinnati @entity1 's Hospital Medical Center (CCHMC). Data collected included: age, gender, location of treatment (outpatient, inpatient), @entity2704 duration, diagnosis, severity, the addition of @entity230 to treatment protocols, and recurrence of @entity2704 at 48 and 72 hours after discharge. Data were analyzed using Fisher's exact tests, logistic regression with backward elimination for variable selection, and least squares means slicing with associated odds ratios. RESULTS: Charts from 207 pediatric @entity1 were analyzed. Using logistic regression analysis: location, gender, diagnosis, and age were all found to be significant predictors of @entity2704 (P   <   .05). @entity1 treated in the inpatient setting were significantly less likely to experience recurrence compared to @entity1 treated in an outpatient infusion unit (OR   =   0.32; 95% CI 0.17-0.61, P   =   .0002). Male @entity1 with a diagnosis of episodic @entity2704 were significantly less likely to experience recurrence than male @entity1 with chronic @entity2704 (OR 0.17; 95% CI 0.04-0.73; P   =   .0074). The inclusion of @entity230 in this study population showed no significant reduction in @entity2704 . The probability of recurrence decreased with age for episodic @entity2704 @entity1 , while the probability increased with age for chronic @entity2704 @entity1 . CONCLUSIONS: Recurrence is an important consideration when treating intractable @entity2704 . Age, gender, diagnosis, and location of treatment correlate with @entity2704 , but the inclusion of @entity230 does not. Considering these factors in the management of @entity2704 may improve the outcome of these @entity1 and reduce the risk of recurrence.

Factors Influencing Migraine Recurrence After Infusion and Inpatient Migraine Treatment in XXXX and Adolescents.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'Children'] @entity2704 :: ('MESH:D008881', 'Disease') :: ['migraine', 'migraines', 'migraine recurrence'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids']
@entity1 :: (9606,Species) :: ['Children']
