Thyroid hormones act on several aspects of metabolic and energy homeostasis influencing body weight, thermogenesis, and lipolysis in adipose tissue. @entity1253 are biologically active substances produced by adipocyte with different physiological functions. These substances have multiple effects on several tissues acting on the intermediate and energy metabolism. For these reasons, attention has recently been focused on the possible relationship between adipocytokines, thyroid status, and @entity1374 . @entity1243 , a signal of satiety to the brain and regulator of insulin and @entity413 metabolism, reflects the amount of fat storage and is considered as a pro-inflammatory adipocytokine. @entity1254 is inversely related to the degree of adiposity, @entity1720 , and may have antiatherogenic and anti-inflammatory properties. @entity23945 impairs @entity413 homeostasis and insulin action in @entity19 but not in @entity1 . @entity23945 might be considered a pro-inflammatory adipocytokine and participate in @entity28 -associated @entity32 . Several reports indicate that @entity1243 regulates thyroid function at hypothalamic-hypophyseal level and, conversely, thyroid hormones might control @entity1243 metabolism at least in some animals studies. Both @entity1254 and thyroid hormones share some physiological actions as reduction of body fat by increasing thermogenesis and lipid oxidation. @entity23945 also seems to be regulated by thyroid hormones, at least in @entity35 . @entity1374 does not significantly affect serum @entity1243 concentrations. Serum levels of @entity1254 are no influenced by @entity1374 ; however, @entity1378 is associated with normal or elevated @entity1254 levels. Finally, discordant results in @entity23945 levels in @entity1374 have been reported in @entity1 .

Influence of XXXX on serum concentrations of adipocytokines.

@entity23945 :: ('MESH:D052243', 'Chemical') :: ['Resistin', 'resistin'] @entity1 :: ('9606', 'Species') :: ['humans'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity19 :: ('10090', 'Species') :: ['mice'] @entity1243 :: ('3952', 'Gene') :: ['leptin', 'Leptin'] @entity1253 :: ('MESH:D054392', 'Chemical') :: ['Adipocytokines'] @entity1378 :: ('MESH:D006980', 'Disease') :: ['hyperthyroidism'] @entity1254 :: ('9370', 'Gene') :: ['Adiponectin', 'adiponectin'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity1720 :: ('MESH:D007333', 'Disease') :: ['increases insulin sensitivity'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroid dysfunction', 'Thyroid dysfunction', 'thyroid hypofunction']
@entity1374 :: (MESH:D013959,Disease) :: ['thyroid dysfunction']
