PURPOSE/OBJECTIVES: To examine associations among oxidative stress, fine and @entity227 , and behavioral adjustment in @entity1 receiving chemotherapy for @entity981 ( @entity981 ).    . DESIGN: A prospective, repeated-measures design.    . SETTING: Two pediatric oncology settings in the southwestern United States.   . SAMPLE: 89 @entity1 with @entity981 were followed from diagnosis to the end of chemotherapy.   . METHODS: Serial cerebrospinal fluid samples were collected during scheduled lumbar punctures and analyzed for oxidative stress biomarkers. @entity1 completed fine motor dexterity, visual processing speed, and @entity227 measures at three time points. Parents completed @entity1 behavior ratings at the same times.   . MAIN RESEARCH VARIABLES: Oxidative stress, fine motor dexterity, visual processing, @entity227 , and behavioral adjustment.    . FINDINGS: @entity1 with @entity981 had below-average fine motor dexterity, visual processing speed, and @entity227 following the induction phase of @entity981 therapy. By end of therapy, visual processing speed normalized, and fine motor dexterity and @entity227 remained below average. Oxidative stress measures correlated with fine motor dexterity and @entity227 . Decreased motor functioning was associated with increased @entity2915 and @entity148 .    . CONCLUSIONS: Oxidative stress occurs following chemo-therapy for childhood @entity981 and is related to @entity227 .   . IMPLICATIONS FOR NURSING: Early intervention should be considered to prevent fine motor and @entity227 , as well as @entity146 .   .

Oxidative Stress, Motor Abilities, and Behavioral Adjustment in @entity1 Treated for XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Children', 'child'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual-motor abilities', 'visual-spatial deficits', 'visual-motor integration', 'impaired fine motor skills and visual symptoms'] @entity981 :: ('MESH:D054198', 'Disease') :: ['ALL', 'acute lymphoblastic leukemia'] @entity146 :: ('MESH:D001523', 'Disease') :: ['behavioral problems'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity2915 :: ('MESH:D006948', 'Disease') :: ['hyperactivity']
@entity981 :: (MESH:D054198,Disease) :: ['Acute Lymphoblastic Leukemia']
