PURPOSE: To describe and compare graft survival and intraocular pressure (IOP) control after penetrating keratoplasty (PK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with @entity22958 . DESIGN: Retrospective case series. METHODS: Multicenter study conducted at the Singapore National Eye Centre (SNEC) and Price Vision Group. Twenty-nine consecutive eyes with ICE syndrome that underwent keratoplasty between 1991 and 2011 were identified from the SNEC transplant database and Price Vision Group @entity1 database and the following data extracted: demographics, graft failure, IOP indices, and @entity726 treatment pre- and postkeratoplasty. The main outcome measures were graft failure and need for additional IOP-lowering treatment after keratoplasty. RESULTS: The mean follow-up duration was 7.0    4.9 years in the PK group (n  = 17) and 4.0    2.6 years in the DSAEK group (n  = 12). After a mean of 4.1    3.1 years, 37.9% of grafts (11/29) failed: 7 PK compared to 4 DSAEK (P  = .72). The graft failure rate was 50% in eyes with @entity726 surgery vs 31.6% in those without (P  = .43). Additional @entity726 treatment was required in 37.9% of eyes (11/29): 41.2% of PK eyes and 50% of DSAEK eyes (P  = .28) Eyes that had undergone @entity726 surgery before keratoplasty were less likely to require escalation of IOP-lowering therapy postkeratoplasty (9.1% vs 50%, P  = .03). CONCLUSIONS: One-third of grafts failed after keratoplasty for ICE syndrome at a mean duration of 4 years and additional IOP-lowering treatment was required in 37.9%. Both PK and DSAEK had similar outcomes with regard to graft failure and IOP control.

Graft failure and intraocular pressure control after keratoplasty in XXXX .

@entity1 :: ('9606', 'Species') :: ['patient'] @entity22958 :: ('MESH:D057129', 'Disease') :: ['iridocorneal endothelial (ICE) syndrome'] @entity726 :: ('MESH:D005901', 'Disease') :: ['prekeratoplasty glaucoma', 'glaucoma']
@entity22958 :: (MESH:D057129,Disease) :: ['iridocorneal endothelial syndrome']
