UNASSIGNED: 9728 Background: To evaluate the age of presentation of @entity0 ( @entity0 ) and its correlation with the expression of @entity1722 and hormonal receptors in Mexican @entity1 Methods: A descriptive analysis of 101 @entity1 with @entity0 was carried out in the Oncology Hospital 'Siglo XXI' during the year 2002-2003.Testing of herceptes and determination of hormonal receptors were correlated with the clinical stage and the @entity1 age. RESULTS: The average @entity1 age was 52 years (range 29-86), the most frequent clinical stage was stage III (58.41%). 26 @entity1 with @entity1722 positive, 75 @entity1 @entity1722 negative. 37 @entity1 with RE positive, 62 RE negative, 37 @entity1 with @entity6391 positive and 61 with @entity6391 negative. A description of the subgroups is detailed in the table below. [Figure: see text] Undeterminable = 2, non classification = 5 When correlating @entity1722 /neu with hormonal receptors the following results were established: @entity1722 positive is associated with RE negative (80.76%) and with RE positive (15.38%); @entity1722 /neu negative is associated with @entity6391 negative (84.61%), and with @entity6391 positive (7.69%), with RE negative (54.60%), and with RE positive (44.00%). CONCLUSIONS: The age of presentation of @entity0 is at least 10 years earlier than in developed countries, the over-expression of @entity1722 is similar to that reported in the literature, and in the same way the appearance of positive hormonal receptors is associated with under-expression of @entity1722 . The RE and @entity6391 are expressed in equal percentage in @entity1 with @entity1722 negative. Environmental and inherent factors need studying in order to investigate the early appearance of @entity0 . No significant financial relationships to disclose.

Early appearance of @entity0 ( XXXX ) and its patterns of expression for @entity1722 and hormonal receptors (HR).

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer', 'BC'] @entity1722 :: ('2064', 'Gene') :: ['HER-2', 'HER-2/NEU', 'HER-2/neu'] @entity6391 :: ('MESH:D012174', 'Disease') :: ['RP']
@entity0 :: (MESH:D001943,Disease) :: ['BC']
