BACKGROUND: Neutrophil-lymphocyte ratio (NLR) has been shown to be associated with prognosis in various solid @entity5 . This study aimed to evaluate the prognostic role of NLR in @entity1 with @entity957 ( @entity957 ). METHODS: A total of 141 @entity957 @entity1 were retrospectively reviewed. @entity1 ' demographics were analyzed along with clinical and pathologic data. The optimal cutoff value of NLR was determined using receiver operating characteristic (ROC) curve analysis. The impact of the NLR and other potential prognostic factors on disease-free survival (DFS) and @entity1349 ( @entity1349 ) was assessed using the Kaplan-Meier method and multivariate Cox regression analysis. RESULTS: The optimal cutoff value of the NLR was 2.17. In the NLR    <=   2.17 group, the 1-, 3-, and 5-year DFS rates were 88.2, 73.9 and 69.1  %, respectively, while in the NLR   >   2.17 group, the DFS rates were 83.0, 54.6 and 49.2  %, respectively. Correspondingly, the 1-, 3-, and 5-year @entity1349 rates were 98.9, 85.1 and 77.4  % in the NLR    <=   2.17 group and 97.9, 63.8 and 53.3  % in the NLR   >   2.17 group, respectively. The multivariate Cox proportional hazard model analysis showed that NLR   >   2.17 was a prognostic factor for both DFS [hazard ratio (HR)   =   1.869; 95  % confidence interval (CI) 1.078-3.243; P   =   0.026] and @entity1349 (HR =2.177; 95  % CI 1.208-3.924; P   =   0.010). CONCLUSION: Our results showed that elevated preoperative NLR was an independent predictor of poor prognosis for @entity1 with @entity957 after surgical resection.

Preoperative neutrophil-to-lymphocyte ratio is an independent prognostic marker in XXXX with @entity957 .

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity957 :: ('MESH:D002294', 'Disease') :: ['LSCC', 'laryngeal squamous cell carcinoma'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity1 :: (9606,Species) :: ['patients']
