Three @entity1 with spinal primary diffuse-type @entity2967 (DTGCT) received surgical treatment in our department between 2002 and 2012. All 3 @entity1 were female and aged 23, 33, and 44 years. The mean time from symptom onset to diagnosis was 17 months (range, 5-24 months). One case involved the C1 right lateral mass and C2 vertebral body, the second involved the C1-2 left lateral masses and C2 vertebral body, and the third involved the C5-7 left lateral mass and C6 vertebral body. All @entity1 underwent computed tomographyguided biopsy to confirm the diagnosis of @entity2967 . Gross total resection was achieved in all @entity1 , including 2 piecemeal resections and 1 en-bloc resection. The mean follow-up time was 6 years (range, 1-11 years), and there was no sign of recurrence in the @entity1 . Seventy cases have been identified so far in the English literature. The male to female ratio is 1:1.38. The mean @entity1 age is 38.5    17.9 years. The @entity5 distribution includes 32 cases in the cervical spine, 14 in the thoracic spine, 22 in the lumbar spine, and 1 in the sacrococcygeal region. The recurrence rate for @entity1 who underwent gross total resection was 7.7%, and @entity5 progression was observed in 66.7% of @entity1 who underwent subtotal resection. Above all, DTGCT is a rare primary @entity18431 . Preoperative image-guided biopsies play an important role in the diagnosis and treatment strategy. Gross total resection is the best treatment strategy and can reduce the recurrence rate.

Primary diffuse-type XXXX of the spine: a report of 3 cases and systemic review of the literature.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity18431 :: ('MESH:D013125', 'Disease') :: ['spinal neoplasm'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity2967 :: ('MESH:D005870', 'Disease') :: ['tenosynovial giant cell tumor']
@entity2967 :: (MESH:D005870,Disease) :: ['tenosynovial giant cell tumor']
