BACKGROUND: Inflammation and cell @entity39 are one of the consequences that accompany @entity0 . However, @entity32 and cell @entity39 are well known to be involved in stimulation of cellular and humeral immunity. OBJECTIVES: The aim of this study is to investigate the immune response to the @entity32 that accompanies @entity5 through measuring plasma concentration of antinuclear antibodies (ANAs) and anti-double stranded deoxyribonucleic acid antibodies (ADSDAs). MATERIALS AND METHODS: Thirty-five newly diagnosed @entity0 @entity1 were involved in this study from the Radiation Isotopes Center Khartoum (RICK) compared to 18 age- and sex-matched control subjects. Intravenous blood sample was obtained from each study subject and Enzyme Linked Immuno Sorbent Assay (ELISA) technique was used to determine the concentration of the two antibodies. RESULTS: Regarding the ANA concentration in the @entity1 ; the range was 0.7-1.8 IU/ml, mean was 0.96, and the @entity5494 ( @entity5494 ) was 0.25; while the range of theconcentration in the control subjects was 0.3-0.6 IU/ml, mean was 0.47, and @entity5494 was 0.07. However, when the means of @entity1 and controls were compared, the difference was significant (P < 0.000). Concerning the result anti-double stranded DNA (anti-dsDNA), its concentration range in the @entity1 was 2.6-151.9 IU/ml, themean was 55.2, and @entity5494 was 25.6, while in healthy @entity1 concentration range was 26.1-97.3 IU/ml, the mean was 50.3, and @entity5494 was 16.9. There was no significant change between the @entity1 and controls (P = 0.46). CONCLUSION: The ANA concentration in the @entity1 was significantly increased, while there was no significant difference between the results of ADSDAs in the @entity1 and the control subjects.

Autoantibodies in the sera of XXXX patients: Antinuclear and anti-double stranded DNA antibodies as example.

@entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5494 :: ('MESH:D010262', 'Disease') :: ['standard deviation', 'SD'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
