BACKGROUND: @entity1 with pulmonary @entity3 from @entity14 can benefit from surgical removal. However, the biological determinants of postsurgical outcome are not completely elucidated. We evaluated the role of host systemic @entity32 status in this setting. METHODS: The modified Glasgow prognostic score (based on serum @entity1851 and albumin levels) and the neutrophil-to-lymphocyte (NTL) ratio were obtained from 44 @entity1 who received curative-intent metastasectomy, and were used as indicators of systemic @entity32 status. We tested the impact of both of these parameters on @entity1349 ( @entity1349 ) and progression-free survival (PFS), as well as their correlation with other well-known prognosticators. RESULTS: Five-year PFS and @entity1349 rates were 18% and 49%, respectively. At univariate analysis, multiple @entity3 , disease-free interval <36 months, and a Glasgow score of 2 (P = 0.031) were significantly associated to a worse PFS rate. A NTL ratio >3 predicted disease progression in the short-term (P = 0.036), but the effect on late events was weaker (P = 0.079). Factors associated with worse @entity1349 were multiple @entity3 (P = 0.002), elevated carcinoembryonic antigen (P = 0.009), a Glasgow score of 2 (P = 0.029), and a faster @entity3 growth (P = 0.008). At Cox regression analysis, neither a Glasgow score of 2, nor elevated NTL ratio showed an independent effect on survival rates. CONCLUSIONS: Systemic @entity32 scores did not perform well as independent survival prognosticators in @entity1 undergoing curative-intent pulmonary metastasectomy. Further investigation is warranted to evaluate whether these measurements could still be useful when restricting the analysis to specific @entity1 subcategories or to diverse postoperative phases.

Role of systemic XXXX scores in pulmonary metastasectomy for @entity14 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein']
@entity32 :: (MESH:D007249,Disease) :: ['inflammation']
