BACKGROUND: @entity778 ( @entity778 ) is a prevalent and potentially fatal @entity1800 associated with @entity1003 . So far, the coagulation profile of @entity778 patients with @entity882 has not been assessed through a viscoelastic test such as rotational thromboelastometry. We aimed to describe the prevalence and characteristics of @entity854 in @entity779 outpatients with @entity882 , addressed by both rotational thromboelastometry and conventional coagulation tests. METHODS: This was a cross-sectional study conducted between April 6(th) and May 5(th) 2015 in S  o Paulo, Brazil during a dengue outbreak. Thromboelastometry (ROTEM  ) and the conventional coagulation tests prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (aPTT), thrombin time (TT), platelet count and fibrinogen levels were performed in 53 patients with @entity778 and @entity882 . RESULTS: Despite a median interquartile range (IQR) platelet count of 77 (63-88) x 10(9)/L in @entity778 patients, conventional coagulation tests and plasma fibrinogen levels were within the normal range. Subjects demonstrated hypocoagulability in 71.7% (38/53) in INTEM and 54.7% (29/53) in EXTEM @entity778 patients. FIBTEM analyses detected only 5.7% (3/53) with hypocoagulability among this population. The median (IQR) clotting time (CT), clot formation time (CFT) and @entity4461 ( @entity4461 ) on INTEM were, respectively, 177 (160-207) sec, 144 (108-178) sec and 48 (42-52) mm. On EXTEM, median (IQR) CT, CFT and @entity4461 were, respectively, 69 (65-78) sec, 148 (126-198) sec and 49 (44-55) mm. Median (IQR) @entity4461 on FIBTEM was 15 (13-18) mm. CONCLUSION: @entity73 is highly prevalent in @entity778 patients with @entity882 , particularly in INTEM and EXTEM analyses, while standard coagulation tests are normal in this setting. Clinical implications remain to be established.

Thromboelastometry analysis of XXXX patients: a cross-sectional study.

@entity778 :: ('MESH:D015658', 'Disease') :: ['Dengue virus infection', 'DVI'] @entity882 :: ('MESH:D013921', 'Disease') :: ['thrombocytopenia'] @entity73 :: ('MESH:D003072', 'Disease') :: ['Thromboelastometry impairment'] @entity1003 :: ('MESH:D001778', 'Disease') :: ['coagulopathy'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral disease'] @entity854 :: ('MESH:D018376', 'Disease') :: ['coagulation abnormalities'] @entity4461 :: ('MESH:D020141', 'Disease') :: ['MCF', 'maximum clot firmness'] @entity779 :: ('MESH:D003715', 'Disease') :: ['dengue fever']
@entity882 :: (MESH:D013921,Disease) :: ['thrombocytopenic dengue']
