BACKGROUND: The aim of the study was to evaluate the value of high sensitivity cardiac troponin (hs-cTn) for identifying high-risk @entity1 . METHODS AND RESULTS: 187 @entity1 admitted with @entity712 (without myocardialinfarction) were consecutively included; hs-cTn was measured at admission; therelation between elevated hs-cTn and the clinical outcome during hospitalization and at90 days was analyzed;93% (n=174) had hs-cTn above the maximal normal value (14ng/L); median hs-cTnwas 42ng/L (IQR 24-81). @entity1 with ejection fraction (EF)  <=45% had higher hs-cTnvalues (p=0.0004). @entity1 with @entity998 ( @entity998 ) or shock had higher troponin levels compared with those with less severe clinical presentations (p=0.004). @entity1 who required inotropic presented higher troponin values (p=0.002),troponin values were also higher in those requiring complex therapies (intra-aorticballoon pump, mechanical ventilation or hemodialysis, p=0.002). At 90-day follow-up,28 @entity1 died (15,5%) and 27 rehospitalizations occurred (55 events). The risk ofevents was greater in @entity1 with hs-cTn>42ng/L (0.021), low blood pressure atadmission (p=0.002), @entity998 or shock (p<0.0001), EF <=45% (p=0.005) and inotropic use(p<0.0001). In multivariate analysis, only inotropic agents requirements was associated independently with high risk of @entity204 or rehospitalizations at 90 days (p=0.007). CONCLUSIONS: Elevation of hs-cTn is a finding almost constant in @entity1 withde compensated @entity712 . In subjects with higher troponin levels @entity67 is frequent. The use of hs-cTn for risk stratification at admission helps toidentify populations with poor outcome during hospitalization and higher risk of @entity204 or rehospitalizations during follow-up who will require rapid implementation of an aggressive treatment.

High sensitive troponin is associated with high risk clinical profile and outcome in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity712 :: ('MESH:D006333', 'Disease') :: ['acute heart failure', 'heart failure'] @entity998 :: ('MESH:D002303', 'Disease') :: ['LCOS', 'low cardiac output syndrome'] @entity67 :: ('MESH:D018754', 'Disease') :: ['ventricular dysfunction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity712 :: (MESH:D006333,Disease) :: ['acute heart failure']
