OBJECTIVE: The aim of this study was to assess the @entity79 distribution and analyze the frequency of the bullhead sign in @entity1 with SAPHO ( @entity603 , acne, @entity1569 , @entity4916 , and @entity4421 ) syndrome using @entity79 ( @entity79 ) in a relatively populous study population. METHODS: In this study, the Nuclear Medicine Department's records of one center were retrospectively reviewed and the @entity1 who fulfilled the diagnostic criteria for @entity17829 and underwent @entity32621 @entity79 were identified over a 16-year period. The following data were collected from @entity1 , including age, sex, surgically proved pathology of the @entity79 , @entity79 surveillance interval, and @entity17829 components. The @entity79 distribution and the frequency of bullhead sign involving the manubrium and bilateral sternoclavicular junctions were analyzed. RESULTS: Forty-eight @entity1 were enrolled in this study. The initial @entity79 indicated bone involvement in all of the 48 (100%) @entity1 , in whom the most commonly affected region was the anterior chest wall (ACW) (100%, 48/48). The frequency of the upper costosternal junction involvement was the highest (38/48, 79.2%), and 28.9% (11/38) @entity1 were found to show isolated involvement of the first rib in ACW. The frequency of the bullhead sign was only 22.9% (11/48, 95% CI: 12.0-37.3). In the eight (16.7%, 8/48) @entity1 who were followed up using @entity79 with an interval that ranged from 1 to 10 years, one @entity1 with an initially single sternoclavicular junction lesion developed a typical bullhead sign over 10 years; other @entity1 with or without the initial typical bullhead sign showed stable appearance over 1-4 years. CONCLUSION: This retrospective study shows that in @entity1 with proposed @entity17829 , the @entity79 are most likely located in ACW, and the configuration of the bullhead sign is characteristic, but not entirely sensitive. The value of upper costosternal junction involvement, especially the first rib, may be underevaluated.

Is the bullhead sign on bone scintigraphy really common in the XXXX with @entity17829 ? A single-center study of a 16-year experience.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity4916 :: ('MESH:D015576', 'Disease') :: ['hyperostosis'] @entity1569 :: ('MESH:D011565', 'Disease') :: ['pustulosis'] @entity603 :: ('MESH:D013585', 'Disease') :: ['synovitis'] @entity79 :: ('MESH:D001847', 'Disease') :: ['WBBS', 'bone lesions', 'bone lesion', 'whole-body bone scintigraphy'] @entity17829 :: ('MESH:D020083', 'Disease') :: ['SAPHO syndrome'] @entity32621 :: ('MESH:D013669', 'Chemical') :: ['Tc-99m-methylene diphosphonate'] @entity4421 :: ('MESH:D010000', 'Disease') :: ['osteitis']
@entity1 :: (9606,Species) :: ['patient']
