Two-staged resection arthroplasty with delayed reimplantation is currently the method of choice for treatment of an @entity281 . There is paucity of data regarding the risk factors for reinfection after reimplantation. The objective of this study was to determine the efficacy of two-stage resection arthroplasty for infected THA and to identify risk factors for reinfection. The outcome of this procedure was evaluated in 54 consecutive @entity1 at our institution from January 1999 to August 2005. The mean follow-up time for @entity1 who were successfully treated was 32 months (range: 24 to 76 months). Infection with @entity3256 -resistant organisms occurred in 33 @entity1 (61%). Recurrent @entity281 was diagnosed in 14 @entity1 (26%) after the second stage reimplantation procedure at an average of 10.6 months. An elevated ASA, which is an indicator of advanced comorbid health status, and @entity281 with @entity3256 -resistant organisms were risk factors for treatment failure. An additional 8% of the cohort developed early mechanical failure at a mean of 13.8 months. The increase in the number of resistant organisms and the rise in the number of @entity1 with comorbid conditions have compromised the efficacy of two-stage exchange arthroplasty. Hence novel techniques for the treatment of @entity281 are desperately needed.

XXXX : are current treatment strategies adequate?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infected total hip arthroplasty', 'periprosthetic infection', 'infection'] @entity3256 :: ('MESH:D008712', 'Chemical') :: ['methicillin']
@entity281 :: (MESH:D007239,Disease) :: ['Periprosthetic infection']
