BACKGROUND AND PURPOSE: Little is known about sex-specific @entity64 hospitalization rates among middle-aged individuals. This study assessed recent temporal trends in @entity64 hospitalizations among @entity1 aged 35 to 64 years in the United States. METHODS: The Nationwide Inpatient Sample was used to identify individuals with a primary or secondary discharge diagnosis of @entity64 between 1997 and 2006 (n=3,161,752). Age-adjusted sex-specific rates of @entity63 and @entity64 hospitalizations were assessed among individuals aged 35 to 64 years. RESULTS: Over the study period, @entity64 hospitalization rates per 100 000 decreased by 10% from 66.7 to 60.3 (trend P<0.01) in @entity1 and 8% from 52.7 to 48.3 (trend P<0.001) in @entity1 . The 55- to 64-year age group drove reductions in hospitalization rates: slope (rate of change per year)=-12.3 for @entity1 and -8.9 for @entity1 (both P<0.001). Rates increased slightly in @entity1 and @entity1 aged 35 to 44 years and remained stable for @entity1 aged 45 to 54 years. @entity64 subtype analysis revealed that rates of @entity385 hospitalization increased and @entity64 hospitalization remained stable among individuals aged 35 to 44 years. Rates of @entity63 and @entity64 hospitalizations remained stable among those aged 45 to 54 years and decreased among @entity1 aged 55 to 64 years. CONCLUSIONS: From 1997 to 2006, @entity63 and @entity64 hospitalization rates declined among individuals aged 55 to 64 years and remained stable among @entity1 aged 45 to 54 years; @entity385 hospitalization rates increased among individuals aged 35 to 44 years. Further studies are needed to assess and address increases in @entity385 hospitalizations among younger individuals.

Recent patterns of sex-specific XXXX hospitalization rates in the United States.

@entity1 :: ('9606', 'Species') :: ['women', 'persons', 'men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'Stroke', 'hemorrhagic stroke'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic']
@entity64 :: (MESH:D020521,Disease) :: ['midlife stroke']
