UNASSIGNED: The @entity5761 ( @entity5761 ) is a childhood @entity302 . Incidence: 1/1.000.000/year, prevalence: 15/100.000. @entity5761 covers 5-10% of @entity302 @entity1 and 1-2% of childhood @entity302 . Also referred to as cryptogenic or symptomatic generalized @entity302 . @entity5761 is characterized by: multiple @entity410 (atypical absences, axial tonic @entity410 and @entity3148 ), diffuse slow cryptic EEG waves when awake (<3 Hz), fast rhythmic peaks (10 Hz) during sleep, @entity1032 and @entity1314 . The @entity5761 is not responding to treatment. Some new drugs have proven to be effective in controlling the disease (Felbamate, @entity2812 , @entity1771 , @entity4677 ). The mortality rate is about 5%; only rarely death is due to @entity302 , which is usually caused by @entity64 or @entity302 episodes. Here we describe the case of a 45-year-old female @entity1 with @entity5761 , severe @entity1371 , @entity1032 and focal @entity410 . Normal renal function: @entity1011 0.9 mg/dl, @entity1133 26 mg/dl, @entity1011 clearance 96 ml/min, serum @entity972 levels to the minimum: 3.5 mEq/L. This level of @entity972 , however, had been achieved with the assumption of 8 oral tablets/day of @entity4337 . Osmotic diuresis, use of diuretics, Bartter, Gitelman (normal urinary @entity460 and @entity1760 ) and pseudo-Bartter syndromes were all excluded whereas @entity1368 was found. Our findings lead to @entity1371 related to assumption of @entity1771 and @entity1368 . Reduction in drug intake was not effective due to the increased @entity410 , so the drug was maintained, along with @entity972 supplementation. In conclusion, the @entity1 has been diagnosed with @entity1371 and iatrogenic @entity1368 , rare in our outpatient practice.

[ XXXX in @entity5761 ].

@entity1 :: ('9606', 'Species') :: ['patient', 'patients'] @entity5761 :: ('MESH:D065768', 'Disease') :: ['Lennox-Gastaut Syndrome', 'LGS'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['mental retardation'] @entity4677 :: ('MESH:C026098', 'Chemical') :: ['Levetiracetam'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1133 :: ('MESH:D014508', 'Chemical') :: ['urea'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity1371 :: ('MESH:D007008', 'Disease') :: ['hypokalemia'] @entity1771 :: ('MESH:C052342', 'Chemical') :: ['topiramate', 'Topiramate'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsies', 'epileptic', 'epileptic encephalopathy', 'epilepsy'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity3148 :: ('MESH:D004831', 'Disease') :: ['sudden atonic or myoclonic falls'] @entity1314 :: ('MESH:D010554', 'Disease') :: ['personality disorders'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity1368 :: ('MESH:D006929', 'Disease') :: ['hyperaldosteronism', 'aldosteronism'] @entity2812 :: ('MESH:C047781', 'Chemical') :: ['Lamotrigine'] @entity4337 :: ('MESH:D011189', 'Chemical') :: ['potassium chloride'] @entity1760 :: ('MESH:D008274', 'Chemical') :: ['magnesium']
@entity1371 :: (MESH:D007008,Disease) :: ['Hypokalemia']
