BACKGROUND: Postoperative sore throat is one of the most common complications after endotracheal intubation. Both @entity3652 and @entity1760 can block @entity1024 ( @entity3391 ) receptors and provide central and local analgesia. OBJECTIVES: To compare the effect of @entity2399 and @entity3652 gargle on the incidence and severity of postoperative sore throat. @entity1 AND METHODS: A total of 100 @entity1 candidate for emergency acute @entity698 surgery were enrolled in the study. @entity1 in @entity3652 group received @entity3652 gargle (0.5 mg/kg) and @entity1760 group received @entity2399 gargle (20 mg/kg up to 30 mL dextrose water 20%) 15 minutes before the operation. @entity1 complaint of postoperative sore throat, and its severity measured by visual analogue scale (VAS) were recorded at baseline in recovery room, and then 2, 4, and 24 hours after operation. RESULTS: There were no significant differences between age, sex, and body mass index (BMI) between two groups of @entity1 . Hemodynamics of @entity1 , including blood pressure, respiratory rate, @entity26 saturation %, and conscious state were not significantly different (P > 0.05). Number of @entity1 with sore throat were significantly lower in @entity1760 group compared to @entity3652 group at 2 (P = 0.032), 4 (P = 0.02), and 24 hours (P = 0.01) after the operation. @entity158 score (VAS) was significantly lower in @entity1760 group compared to @entity3652 group at 2 (P = 0.019), 4 (P = 0.028), and 24 hours (P = 0.014) after the operation. CONCLUSIONS: @entity1760 at low dose decreases sore throat and @entity158 severity more effectively compared to @entity3652 gargle.

@entity1760 and XXXX Gargle and Postoperative Sore Throat.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS', 'Patient'] @entity1024 :: ('CHEBI:31882', 'Chemical') :: ['N-methyl-D-aspartic acid'] @entity2399 :: ('MESH:D008278', 'Chemical') :: ['magnesium sulfate'] @entity698 :: ('MESH:D001064', 'Disease') :: ['appendicitis'] @entity3391 :: ('D016202', 'Chemical') :: ['NMDA'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity3652 :: ('MESH:D007649', 'Chemical') :: ['ketamine', 'Ketamine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'Sore throat pain'] @entity1760 :: ('MESH:D008274', 'Chemical') :: ['magnesium', 'Magnesium']
@entity3652 :: (MESH:D007649,Chemical) :: ['Ketamine']
