High-sensitivity @entity1851 ( @entity1851 ), proposed as a new coronary risk marker, may reflect either an acute phase reaction or the level of chronic @entity32 . Thus, @entity1851 may be less predictive of long-term outcomes when measured after @entity583 ( @entity4620 ) than after unstable @entity951 (UAP) or @entity5749 ( @entity5749 ). A total of 1,360 @entity1 with severe @entity453 (>/=1 stenosis >/=70%) had @entity1851 levels obtained at angiography. Presenting diagnoses were @entity5749 (n = 599), UAP (n = 442), or @entity4620 (n = 319). During follow-up (mean 2.8 years), @entity204 or nonfatal @entity4620 ( @entity4620 ) occurred in 19.5%, 16.1%, and 17.2% (p = NS) with @entity5749 , UAP, and @entity4620 , respectively. Corresponding median @entity1851 levels were 1.31, 1.27, and 2.50 mg/dl (p <0.001). For the overall cohort, increasing age, low ejection fraction, revascularization, and elevated @entity1851 were the strongest of 6 independent predictors for @entity4620 . Among those presenting with @entity5749 , @entity1851 levels above the first tertile were associated with an adjusted hazard ratio of 1.8 (95% confidence interval [CI] 1.2 to 2.8, p <0.009) for @entity4620 . After UAP, the hazard ratio was 2.7 (95% CI 1.4 to 5.0, p <0.002). However, when measured during hospitalization for @entity4620 , @entity1851 was not predictive of long-term outcome (hazard ratio 1.0 [95 % CI 0.5 to 1.7] p = 0.86). In conclusion, predischarge @entity1851 levels are higher after @entity4620 than after UAP or @entity5749 . However, whereas @entity1851 is strongly predictive of long-term @entity4620 for @entity1 presenting with @entity5749 or UAP, it is not predictive shortly after @entity4620 , suggesting that measurements should be delayed until the acute phase reaction is over and levels have returned to baseline.

Usefulness of high-sensitivity XXXX in predicting long-term risk of @entity204 or @entity583 in @entity1 with unstable or @entity5749 or @entity583 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity4620 :: ('MESH:D003699', 'Disease') :: ['D/AMI', 'AMI'] @entity5749 :: ('MESH:D060050', 'Disease') :: ['SAP', 'stable angina pectoris'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina pectoris'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity583 :: ('MESH:D009203', 'Disease') :: ['acute myocardial infarction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein', 'CRP']
@entity1851 :: (1401,Gene) :: ['C-reactive protein']
