The aim of the CASTEL, a population-based (n=3282) prospective study which began 14 years ago, was to identify those items which had a prognostic impact in the elderly, and to evaluate whether the typical cardiovascular risk factors, particularly arterial @entity101 , play a role after the age of 65 years. Initial screening, final follow-up and annual detection of mortality were performed. Mantel-Hanszel approach and multivariate Cox model were used for statistics. Cardiovascular mortality was 23.3% in normotensive, 23.3% in borderline, and 25% in the sustained @entity101 subjects (insignificant difference). In @entity1 , the incidence of @entity64 and @entity453 weakly depended on pulse pressure. @entity64 and @entity583 predicted @entity65 in @entity1 ; @entity6 , uricaemia and high heart rate in @entity1 . In the very old, the predictors were less numerous, and blood pressure was not a predictor whatsoever; pulse blood pressure and murmurs at the neck were especially predictive in @entity1 , @entity712 , @entity644 and @entity591 in @entity1 , historical @entity64 and @entity583 , @entity358 , @entity4346 , @entity6 and uricaemia in both genders. The elderly have a different cardiovascular risk pattern compared to younger @entity1 . @entity101 is not a predictor of coronary and @entity64 mortality. Prognosis depends on pulse pressure rather than on the label ' @entity101 '. Hypercholesterolaemia is not a risk factor. This could simply indicate that elderly @entity1 are the survivors in a population where significant mortality has already made its mark, eliminating those with the worst risk pattern. The two genders have a different risk profile due to sex-specific susceptibility to risk factors.

Weak effect of XXXX and other classic risk factors in the elderly who have already paid their toll.

@entity1 :: ('9606', 'Species') :: ['women', 'people', 'persons', 'men'] @entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity64 :: ('MESH:D020521', 'Disease') :: ['Historical stroke', 'stroke'] @entity712 :: ('MESH:D006333', 'Disease') :: ['historical heart failure'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'Hypertension', 'hypertensive'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity591 :: ('MESH:D013610', 'Disease') :: ['tachycardia'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary disease'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['left ventricular hypertrophy'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular mortality']
@entity101 :: (MESH:D006973,Disease) :: ['hypertension']
