BACKGROUND: Ambulation impairment is a major component of @entity717 in @entity15 ( @entity15 ) and a major target of rehabilitation programs. Outcome measures commonly used to evaluate walking capacities suffer from several limitations. OBJECTIVES: To define and validate a new test that would overcome the limitations of current gait evaluations in @entity15 and ultimately better correlate with the @entity4464 ( @entity4464 ). METHODS: The authors developed the Timed 100-Meter Walk Test (T100MW), which was compared with the Timed 25-Foot Walk Test (T25FW). For the T100MW, the subject is invited to walk 100 m as fast as he/she can. In @entity15 @entity1 and healthy control volunteers, the authors measured the test-retest and interrater intraclass correlation coefficient. Spearman rank correlations were obtained between the T25FW, the T100MW, the Expanded Disability Status Scale (EDSS), and the @entity4464 . The coefficient of variation, Bland-Altman plots, the coefficient of determination, and the area under the receiver operator characteristic curve were measured. The @entity4464 ( @entity4464 ) was compared between the 2 tests. RESULTS: A total of 141 @entity15 @entity1 and 104 healthy control volunteers were assessed. Minor differences favoring the T100MW over the T25FW were observed. Interestingly, the authors demonstrated a paradoxically higher @entity4464 on a long (T100MW) rather than on a short distance walk test (T25FW). CONCLUSION: The T25FW and T100MW displayed subtle differences of reproducibility, variability, and correlation with @entity4464 favoring the T100MW. The maximum walking speed of @entity15 @entity1 may be poorly estimated by the T25FW since @entity15 @entity1 were shown to walk faster over a longer distance.

Comparison of the timed 25-foot and the 100-meter walk as performance measures in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity717 :: ('MESH:D009069', 'Disease') :: ['physical disability'] @entity15 :: ('MESH:D009103', 'Disease') :: ['MS', 'multiple sclerosis'] @entity4464 :: ('MESH:D013009', 'Disease') :: ['mean walking speed', 'maximum walking distance', 'MWS', 'MWD']
@entity15 :: (MESH:D009103,Disease) :: ['multiple sclerosis']
