Cerebral autoregulation is essential in the maintenance of cerebral blood flow. Due to this autoregulation, cerebral perfusion is constant in healthy subjects if blood pressure values are between 50-150 mmHg. In @entity101 @entity1 the curve is right-shifted towards higher blood pressure values (pathological autoregulation). Aggressive blood pressure reduction can lead to severe ischaemia. The authors report the history of a 73-year-old @entity1 with the background history of widespread @entity731 . The @entity1 complained about @entity10 and @entity1296 and was found to have high blood pressure (160/100 mmHg) and increased blood @entity413 (14.8 mmol/l). Prior to his admission an @entity146 blood pressure and blood sugar reduction was carried out and, within a short period of time he became unconscious and was transferred to the department of the authors with the possible diagnosis of @entity64 . On admission the @entity1 was unresponsive, comatose with @entity1109 . Urgent brain computed tomography failed to show any acute alterations. However, repeat CT scan revealed extensive bilateral space occupying ischemic changes involving in territories of both internal carotid arteries with consequent brainstem compression. Computed tomography angiography confirmed bilateral internal carotid @entity432 . The authors conclude that intensive blood pressure reduction result in @entity2806 via hypoperfusion especially in @entity1 with widespread @entity731 and significant carotid vessel pathology. Orv. Hetil., 2014, 155(42), 1685-1689.

[Unfavorable outcome of XXXX lowering of high blood pressure. Case report].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'man'] @entity64 :: ('MESH:D020521', 'Disease') :: ['brainstem stroke'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['ischemic lesions'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggressive'] @entity1109 :: ('MESH:D012678', 'Disease') :: ['brainstem symptoms'] @entity1296 :: ('MESH:D004244', 'Disease') :: ['dizziness'] @entity432 :: ('MESH:D001157', 'Disease') :: ['artery occlusion'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic disease'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity146 :: (MESH:D001523,Disease) :: ['aggressive']
