BACKGROUND: Pediatric sedation is of paramount importance but can be challenging. Fear and anticipatory @entity148 before invasive procedures often lead to uncooperativeness. A novel device (PediSedate) provides sedation through a combination of inhaled @entity3810 and distraction (video game). We evaluated the acceptability and safety of the PediSedate device in @entity1 . METHODS: We enrolled @entity1 between 3 and 9 years old who were scheduled to undergo surgical procedures that required general inhalational anesthesia. After the device was applied, he/she played a video game while listening to the audio portion of the game through the earphones. @entity3810 in @entity26 was administered via the nasal piece of the headset starting at 50% and increasing to 70%, in 10% increments every 8 min. Treatment failures, vital signs, arterial @entity26 saturation, depth of sedation, airway patency, side effects, acceptance of the device and parental satisfaction were all evaluated. RESULTS: Of 100 @entity1 included, treatment failure occurred in 18% mainly because of poor tolerance of the device. At least 96% of the @entity1 who completed the study exhibited an excellent degree of sedation, 22% had side effects, and none experienced serious @entity1224 . @entity1209 were the most common side effects and no @entity1 had @entity1344 . CONCLUSIONS: The PediSedate device combines nonpharmacologic with pharmacologic methods of sedation. Most of the @entity1 we evaluated were able to tolerate the PediSedate device and achieved an adequate degree of sedation.

The PediSedate device, a novel approach to pediatric sedation that provides distraction and inhaled XXXX : clinical evaluation in a large case series.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity3810 :: ('MESH:D009609', 'Chemical') :: ['nitrous oxide', 'Nitrous oxide'] @entity1344 :: ('MESH:D043171', 'Disease') :: ['hemodynamic instability'] @entity1224 :: ('MESH:D000402', 'Disease') :: ['airway obstruction'] @entity1209 :: ('MESH:D020250', 'Disease') :: ['Nausea and vomiting']
@entity3810 :: (MESH:D009609,Chemical) :: ['nitrous oxide']
