OBJECTIVE: The purpose of this study was to determine whether the imaging features of periosteal @entity5 correlate with histopathology. MATERIALS AND METHODS: Twenty-two @entity1 (nine @entity1 and 13 @entity1 ; mean age, 33 years) with pathologically proven periosteal chondroid lesions were retrospectively reviewed. The imaging modalities included conventional radiography (n = 17), CT (n = 10), and MR imaging (n = 14). The images were reviewed by two osteoradiologists, with agreement by consensus. Evaluation criteria included lesion location, mineralization, and size; periosteal reaction; and cortical response. Intramedullary extension, adjacent intramedullary @entity4 , soft-tissue @entity4 , and intrinsic characteristics were also evaluated on MR imaging. After the evaluation, a radiologic diagnosis of @entity83 or @entity511 was obtained. An experienced osteopathologist who was unaware of the @entity1 's medical history and radiologic findings reviewed all histopathology. Agreement between the radiologic and the histopathologic diagnosis was tested using the kappa analysis. Imaging features were correlated with the pathologic findings, and a statistical analysis was performed. RESULTS: Using strict pathologic criteria, we diagnosed 11 @entity83 and 11 @entity511 (nine, grade I; two, grade II). Moderate agreement was reached between the radiologic and the pathologic diagnosis (kappa = 0.55). The size of periosteal @entity511 (range, 3-14 cm; median, 4 cm) was considerably larger than the size of the @entity83 (range, 1-6.5 cm; median, 2.5 cm; p < 0.05). Other imaging features did not significantly correlate with benign versus malignant disease at pathology (all p > 0.05). CONCLUSION: A variable overlap existed in the imaging appearances of benign and malignant periosteal chondroid lesions, with size being the most reliable indicator in distinguishing the two lesions. This and the fact that histologic differentiation of the entities can be difficult, suggests that surgical wide excision may be the most appropriate procedure in treating @entity1 with lesions greater than 3 cm.

XXXX : radiologic evaluation with pathologic correlation.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity511 :: ('MESH:D002813', 'Disease') :: ['chondrosarcoma', 'chondrosarcomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['chondroid tumors'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity83 :: ('MESH:D002812', 'Disease') :: ['chondromas', 'chondroma']
@entity5 :: (MESH:D009369,Disease) :: ['Periosteal chondroid tumors']
