INTRODUCTION: Currently the therapeutic gold standard for medium and low @entity5 is the "en-bloc" excision of the rectum and total mesorectal excision (TME) preserving the autonomous nerve plexus. In @entity5 , complex procedures such as very low anterior resections and intersphincteric resections are used where possible. These procedures can avoid incapacitating operations such as abdominoperineal amputation. The possibilities to perform these procedures even by laparoscopic means, with regard to it's advantages, are still under evaluation. The authors describe their own clinical experiences using such methods. @entity1 AND METHODS: From 2005 to 2010, we performed by laparoscopic procedure 3 anterior resections and 3 inter-sphincteric resections for @entity5 of the low rectum . Medium age of @entity1 was 70 years (range 52-80 years) and male to female ratio was 4/2. Mean operative time was 260 min ( range 220 - 360 min). No laparoscopic procedure was converted to the traditional open surgery. We noted 2 anastomotic leakages of which one required re-operation. Two @entity1 were classified T2 (1 N0 and 1 N1); four @entity1 T3 (3 N0 and 1 N2). In all the cases, resection margins were free. The mean distance from the anal verge was 3,8 cm (range 2,8 - 6 cm). In a mean followup of 48 months ( range 6-54 months), 1 @entity1 developed hepatic @entity3 and no local recurrence was noted. Two @entity1 had urinary retention, resolved spontaneously. One @entity1 presented @entity323 . At 12 months from the operation, one @entity1 had slight incontinence for gas and liquids. CONCLUSIONS: We believe that total mesorectal resection, even associated with sphincter preserving procedures, such as intersphincteric resection, in case of @entity5 , can also be performed by laparoscopic approach with the same oncological and surgical principles of open surgery. However it is necessary to have broad based studies and randomised clinical trials in order to confirm the safety of such procedure and the results obtained.

[Low XXXX : therapeutic options and clinical experience of a single center].

@entity5 :: ('MESH:D009369', 'Disease') :: ['rectal tumours', 'cancer', 'very low rectal tumours', 'very distal tumours'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity323 :: ('MESH:D007172', 'Disease') :: ['erectile dysfunction'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity5 :: (MESH:D009369,Disease) :: ['rectal cancer']
