BACKGROUND: Symptoms and survival of @entity1 with @entity4303 have improved, but development of @entity299 ( @entity299 ) continues to decrease survival. OBJECTIVES: This study aimed to analyze @entity1 outcomes after valve surgery for @entity299 during a 27-year period at 1  institution to determine early and late outcomes and opportunities for improved @entity1 care. METHODS: We retrospectively studied the short-term and long-term outcomes of all consecutive @entity1 with @entity299 who underwent valve replacement at our institution between 1985 and  2012. RESULTS: The records of 195 @entity1 with @entity299 were analyzed. Pre-operative New York Heart Association class was III  or IV in 125 of 178 @entity1 (70%). All had tricuspid valve replacement (159 bioprostheses, 36 mechanical), and 157  underwent a @entity338 . Other concomitant operations included mitral valve procedure (11%), aortic valve procedure (9%), @entity4616 or @entity118 closure (23%), cardiac metastasectomies or biopsy (4%), and simultaneous coronary artery bypass (11%). There were 20 perioperative @entity204 (10%); after 2000, perioperative mortality was 6%. Survival rates (95% confidence intervals) at 1, 5, and 10 years were 69% (63% to 76%), 35%  (28% to 43%), and 24% (18% to 32%), respectively. Overall mortality was associated with older age, cytotoxic chemotherapy, and @entity286 use; 75% of survivors had symptomatic improvement at follow-up. Presymptomatic valve operation was not associated with late survival benefit. CONCLUSIONS: Operative mortality associated with valve replacement surgery for @entity299 has decreased. Symptomatic and survival benefit is noted in most @entity1 when @entity299 is managed by an experienced multidisciplinary team.

Early and Late Outcomes of Surgical Treatment in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity338 :: ('MESH:D011665', 'Disease') :: ['pulmonary valve operation'] @entity4303 :: ('MESH:D002276', 'Disease') :: ['carcinoid syndrome'] @entity299 :: ('MESH:D006331', 'Disease') :: ['carcinoid heart disease', 'CaHD'] @entity118 :: ('MESH:D006344', 'Disease') :: ['atrial septal defect'] @entity4616 :: ('MESH:D054092', 'Disease') :: ['patent foramen ovale'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths']
@entity299 :: (MESH:D006331,Disease) :: ['Carcinoid Heart Disease']
