AIM: Amplitude spectral area (AMSA), an index for analysing @entity2224 ( @entity2224 ) waveforms, is thought to predict the return of spontaneous circulation (ROSC) after electric shocks, but its validity is unconfirmed. We developed an equation to predict ROSC, where the change in AMSA (  AMSA) is added to AMSA measured immediately before the first shock (AMSA1). We examine the validity of this equation by comparing it with the conventional AMSA1-only equation. METHOD: We retrospectively investigated 285 @entity2224 @entity1 given prehospital electric shocks by emergency medical services.   AMSA was calculated by subtracting AMSA1 from last AMSA immediately before the last prehospital electric shock. Multivariate logistic regression analysis was performed using post-shock ROSC as a dependent variable. RESULTS: Analysis data were subjected to receiver operating characteristic curve analysis, goodness-of-fit testing using a likelihood ratio test, and the bootstrap method. AMSA1 (odds ratio (OR) 1.151, 95% confidence interval (CI) 1.086-1.220) and   AMSA (OR 1.289, 95% CI 1.156-1.438) were independent factors influencing ROSC induction by electric shock. Area under the curve (AUC) for predicting ROSC was 0.851 for AMSA1-only and 0.891 for AMSA1+  AMSA. Compared with the AMSA1-only equation, the AMSA1+  AMSA equation had significantly better goodness-of-fit (likelihood ratio test P<0.001) and showed good fit in the bootstrap method. CONCLUSIONS: Post-shock ROSC was accurately predicted by adding   AMSA to AMSA1. AMSA-based ROSC prediction enables application of electric shock to only those @entity1 with high probability of ROSC, instead of interrupting chest compressions and delivering unnecessary shocks to @entity1 with low probability of ROSC.

Novel CPR system that predicts return of spontaneous circulation from amplitude spectral area before electric shock in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['VF', 'ventricular fibrillation']
@entity2224 :: (MESH:D014693,Disease) :: ['ventricular fibrillation']
