PURPOSE: Multiple scores have been described for the assessment of collateralization in acute @entity385 . Currently, there is no gold standard for collateral assessment by CT angiography (CTA). This study compared four frequently used collateral scores with regard to their correlation with early @entity1188 core and mismatch ratio. METHODS: 30 consecutive @entity1 with acute occlusion of the M1 segment or terminal carotid artery were reviewed retrospectively. Collaterals were assessed using dynamic and also single-phase CTA according to grading systems by the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR), Alberta @entity64 Program Early CT Score (ASPECTS) (on collaterals), Christoforidis et al and Miteff et al. The Christoforidis and ASITN/SIR scores, which were initially designed for conventional angiography, were adapted to be applicable to CTA. The scores were compared with respect to early @entity1188 core and mismatch ratio in perfusion CT estimated by RAPID software using Spearman correlation. RESULTS: ASITN/SIR and ASPECTS collateral scores showed good correlation with early @entity1188 core (rho=-0.696, p<0.001 and rho=-0.677, p<0.001) and mismatch ratio (rho=0.609, p<0.001 and rho=0.581, p<0.001). In contrast, the Christoforidis and Miteff scores correlated less well with @entity1188 core (rho=0.245, p=0.191 and rho=-0.272, p=0.145, respectively) and mismatch ratio (rho=-0.329, p=0.075 and rho=0.279, p=0.135, respectively). ASPECTS and ASITN/SIR showed excellent cross-correlation (rho=0.901, p<0.001). CONCLUSIONS: Compared with the Christoforidis and Miteff scores, the modified ASITN/SIR and ASPECTS collateral scores showed consistently higher correlation with the extent of early @entity1188 core and mismatch volume. This is probably because these scores evaluate the extent and delay of vascular enhancement in the affected territory rather than the backflow of contrast medium to the occlusion.

Comparison of four different collateral scores in acute XXXX by CT angiography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['Stroke'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['ischemic stroke']
