PURPOSE OF REVIEW: Complicated infections of the urinary tract (UTI) including @entity2885 and urosepsis are also called febrile UTI. This review describes insights from the literature on this topic since July 2014. RECENT FINDINGS: Recent studies regarding risk factors and consequences of febrile UTI confirmed existing knowledge. It remains difficult to obtain insight into the epidemiology of febrile UTI because urine and blood cultures are frequently missing. The relationship between host and virulence factors of @entity526 was further explored showing that less virulent strains can cause @entity281 in immunocompromised @entity1 . In contrast to obstructive @entity3551 , @entity6 , and being older, @entity1398 was not a risk factor for lower UTI or urosepsis. A randomized controlled trial revealed that @entity59912 - @entity7120 was marginally superior to @entity5553 as treatment for complicated UTI. Case series supported the notion that xanthogranulomatous and @entity2885 are more common in @entity6 @entity1 and that drainage or surgery is often required. SUMMARY: Neutropenia was not a risk factor for lower UTI or urosepsis. When local resistance percentages to the frequently prescribed @entity2887 are high, the combination of @entity59912 - @entity7120 may be an alternative as treatment for complicated UTI. Xanthogranulomatous and @entity2885 need to be considered in @entity6 @entity1 presenting with UTI symptoms.

Febrile urinary tract infections: XXXX and urosepsis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3551 :: ('MESH:C536483', 'Disease') :: ['uropathy'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic', 'diabetes'] @entity7120 :: ('MESH:C043265', 'Chemical') :: ['tazobactam'] @entity5553 :: ('D064704', 'Chemical') :: ['levofloxacin'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1398 :: ('MESH:D009503', 'Disease') :: ['neutropenia'] @entity2887 :: ('MESH:D024841', 'Chemical') :: ['fluoroquinolones'] @entity59912 :: ('MESH:C519491', 'Chemical') :: ['ceftolozane'] @entity2885 :: ('MESH:D011704', 'Disease') :: ['pyelonephritis', 'emphysematous pyelonephritis'] @entity526 :: ('562', 'Species') :: ['Escherichia coli']
@entity2885 :: (MESH:D011704,Disease) :: ['pyelonephritis']
