PURPOSE: To determine the relationship between the blood flow parameters of the optic disc rim and the @entity227 . DESIGN: Observational cross-sectional study. METHODS: Tissue blood flow in the neuroretinal rim within the optic disc was determined with the Heidelberg retina flowmeter(HRF) in 54 eyes of 54 @entity1 with normal tension @entity726 (NTG). @entity1 were selected whose @entity227 were confined to either the superior or inferior hemifield. Blood flow measurements were made in a 10 degrees x 2.5 degrees area of the superior and inferior neuroretinal rim within the optic disc. The @entity450 ( @entity450 ) was calculated by the automatic full-field perfusion image analyzer program, and the ratio of the @entity450 in the superior to the inferior rim areas (the S/I ratio) was calculated from the same HRF image in order to minimize the variation of measurement condition. RESULTS: Inferior rim blood flow is less than superior rim blood flow in @entity1 with superior hemifield defect, and superior rim blood flow is reduced compared to inferior in @entity1 with @entity75 . The mean S/I ratios of the @entity450 in the @entity1 with superior hemifield defect (1.46, n=37) was significantly higher than that in the @entity1 with @entity75 (0.79, n=17; P<0.0001, Mann-Whitney U-test). CONCLUSIONS: The blood flow in the neuroretinal rim was found to correspond to the regional @entity227 in eyes with NTG. Reductions in flow were associated with reductions in function.

Decreased blood flow at neuroretinal rim of optic nerve head corresponds with XXXX in eyes with normal tension @entity726 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual field defect', 'visual field defects', 'glaucomatous visual field changes'] @entity75 :: ('MESH:D001927', 'Disease') :: ['inferior hemifield defect'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity450 :: ('MESH:D006940', 'Disease') :: ['MBF', 'mean blood flow']
@entity227 :: (MESH:D014786,Disease) :: ['visual field deficit']
