BACKGROUND: The risk of recurrence in @entity1316 is affected by socio-demographic variables such as gender, age at onset and marital status and by @entity221 related factors as the length of previous episodes and the total duration of the @entity221 . The present study investigated how the effect of these variables changed with the progression of the @entity221 . METHOD: Using survival analysis, the risk of recurrence was estimated in a case register study including all hospital admissions with primary @entity1316 in Denmark during 1971-1993. RESULTS: Totally, 20350 first admission @entity1 had been discharged with a diagnosis of @entity1316 , @entity308 or @entity162 /circular type. Initially in the course of the @entity221 , @entity162 @entity1 had a substantial greater risk of recurrence compared with unipolar @entity1 . At this time, gender, age and marital status together with the total duration of the @entity221 predicted the risk of recurrence in both unipolar and @entity162 . Some variables had different predictive effect in the two types of @entity221 . Later, especially the duration of the previous @entity221 predicted the risk of recurrence. CONCLUSION: It seems as initially in the course of @entity1316 socio-demographic variables such as gender, age at onset and marital status act as risk factors for further recurrence. Later, however, the @entity221 itself seem to follow its own rhythm regardless of prior predictors. LIMITATION: The data relate to re-admissions rather than recurrence and the findings may be due to decreasing sample sizes during the course of @entity221 . CLINICAL RELEVANCE: The study underscores the importance of the @entity221 process itself.

Predictors of recurrence in XXXX . A case register study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity162 :: ('MESH:D001714', 'Disease') :: ['manic', 'bipolar illness', 'bipolar'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive'] @entity1316 :: ('MESH:D019964', 'Disease') :: ['affective disorder'] @entity221 :: ('MESH:D005334', 'Disease') :: ['illness']
@entity1316 :: (MESH:D019964,Disease) :: ['affective disorder']
