OBJECTIVE: To investigate the indication, timing and methods of surgery for @entity656 . METHODS: There were 5 538 @entity1 with @entity656 ( @entity656 ) were treated in the Union Hospital, Tongji Medical College from January 2005 to December 2014. Of all @entity656 cases, 2 415 @entity1 with @entity656 proved by computed tomography, and 732 @entity1 underwent surgical treatment. Among 732 @entity1 with surgical treatment, 439 (60.0%) were males and two hundreds and ninety-three (40.0%) were females. The median age was 45 years, ranging 20-76 years. Two hundreds and eighty-nine cases were treated with minimally invasive debridement and drainage and 684 cases were treated with @entity1538 . RESULTS: The cure rate of minimally invasive operation was 16.6% (48/289). The rest of the 241 @entity1 were treated furtherly with open necrosectomy. Among 684 @entity1 with open surgery, 523 @entity1 (76.5%) were infected, and the median time from the onset of symptom to first open operation was 46 d (range 19-205 d). There were 115 @entity1 need to surgery again because of @entity39 tissue residual and the reoperation rate was 16.81% (115/684), 684 @entity1 were performed open surgery on average 1.26 times per @entity1 . The @entity260 were @entity548 (37 cases), upper digestive tract @entity292 (34 cases), @entity694 (12 cases), @entity344 (29 cases) and @entity3472 (83 cases). The overall incidence of complications were 28.5% (195/684). Forty-nine cases died after surgery and the mortality rate was 6.7% (49/732). CONCLUSION: Rational surgical indications and timing of surgical intervention are the key to improve the efficacy of @entity788 , @entity1538 is still an effective method for @entity788 .

[Surgical treatment of XXXX : 10-year experience at a single center].

@entity1 :: ('9606', 'Species') :: ['patients', 'person'] @entity788 :: ('MESH:D010190', 'Disease') :: ['necrotizing pancreatitis'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open debridement'] @entity656 :: ('MESH:D019283', 'Disease') :: ['AP', 'acute necrotizing pancreatitis', 'acute pancreatitis'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrotic'] @entity548 :: ('MESH:D006470', 'Disease') :: ['intra-abdominal hemorrhage'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal obstruction'] @entity260 :: ('MESH:D011183', 'Disease') :: ['main postoperative complications'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula'] @entity3472 :: ('MESH:D010185', 'Disease') :: ['pancreatic fistula'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colonic fistula']
@entity788 :: (MESH:D010190,Disease) :: ['necrotizing pancreatitis']
