PURPOSE: Although excellent outcomes are routinely reported following total knee replacement, up to 20  % of @entity1 remain dissatisfied. The aim of this study was to determine whether pre-operative radiographic classification was associated with functional outcomes following surgery. METHODS: A retrospective review of a prospective arthroplasty database identified 256 @entity1 that fulfilled the inclusion criteria over an 18-month period. Baseline demographic data on all @entity1 were collected prospectively. All pre-operative radiographs were assessed using the Kellgren and Lawrence (K_L) classification system. @entity1 were prospectively assessed using the American Knee Society Score pre-operatively and at 1, 3 and 5  years post-surgery. RESULTS: An association was found between the pre-operative radiographic severity of @entity625 and the pre-operative American Knee Society Knee (AKSK) scores, with worsening radiographic grade corresponding to worsening AKSK scores (p  =  0.020). There was an association between K_L classification and improvement in AKSK scores from pre-operative to 1  year (p  =  0.003) and 3  years (p  =  0.04), with K_L grades 3 and 4 demonstrating the most significant improvements. On multivariate regression analysis, K_L classification was the only significant predictor of improvement in AKSK at 1  year (p  =  0.009). No correlation was found between K_L grade and the American Knee Society Functional Scores at any stage. CONCLUSIONS: The results of this study may help to improve satisfaction rates in total knee replacement by targeting treatment. @entity1 can be counselled that although radiographic severity of arthritic changes can predict knee-specific functional improvement, the extent of their global functional improvement cannot. LEVEL OF EVIDENCE: IV.

Severe XXXX predicts greater improvements in function following total knee arthroplasty.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity625 :: ('MESH:D001168', 'Disease') :: ['arthritis']
@entity625 :: (MESH:D001168,Disease) :: ['arthritis']
