OBJECTIVE: Intracranial @entity1653 have a higher rate of recurrence than @entity1653 . However, scant literature is available regarding the treatment and prognosis of these @entity5 after recurrence. The objective of this study was to analyze the treatment outcomes and prognostic factors of @entity1653 after disease recurrence. METHODS: Forty-one cases with clinical characteristics and follow-up data were available in our department from 2000 to 2013. Certain factors, such as gender, age, pre-operative KPS (Karnofsky Performance Status Scale) score, location, pre-recurrence @entity5 precursor, interval time, Simpson grade, histological grade after recurrence and radiotherapy (RT), were selected to study the relationship with the prognosis of the @entity5 . RESULTS: The mean PFS (progression-free survival) and OS (overall survival) in our cases were 40.5    4.7 and 57.1    5.8 months, respectively. The 1-, 3- and 5-year PFS rates were 79.8, 44.1, and 39.2%, respectively, and the corresponding OS rates were 92.4, 66.1 and 48.8%, respectively. The precursors of recurrent @entity5 were @entity1653 , an interval time less than 24 months and a post-recurrence histological diagnosis of @entity1653 might predict an unfavorable outcome. Surgery Simpson I and II can improve the PFS and OS of @entity5 . Because of the limited number of cases, we could not identify a relationship between RT and prognosis. CONCLUSIONS: Recurrent @entity1653 are intractable @entity5 with a high rate of recurrence and @entity204 . Total resection of the @entity5 under relatively safe conditions remains the most suitable treatment strategy.

Treatment response and prognosis after recurrence of XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity1653 :: ('MESH:D008579', 'Disease') :: ['anaplastic meningioma', 'transformed meningiomas', 'benign meningiomas', 'atypical meningiomas'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1653 :: (MESH:D008579,Disease) :: ['atypical meningiomas']
