BACKGROUND AND OBJECTIVE: Although percutaneous nephrolithotomy has many advantages over open surgery, some endocrine and haemodynamic responses have been reported. However, the effects of anaesthetic agents on these responses have not previously been reported. This study compared the effects of @entity2614 and total intravenous anaesthesia using @entity1875 and @entity680 on the haemodynamic and hormonal changes during percutaneous nephrolithotomy. METHODS: Forty-two ASA I-II @entity1 aged between 15 and 65 yr were studied. @entity2614 in Group S (21 @entity1 ) or TIVA in Group TIVA (21) was used for the maintenance of anaesthesia. Haemodynamic variables and serum concentrations of @entity1372 and @entity972 were measured before, during and after the procedure. Arterial blood-gas status, plasma @entity916 , @entity1369 and adrenocorticotrophic hormone concentrations were measured before and during the procedure. RESULTS: Mean heart rate was lower during percutaneous nephrolithotomy in Group TIVA compared with Group S (P < 0.01). The mean systolic and diastolic arterial pressures were not different in both groups at any stage of measurement (P < 0.05). Plasma @entity916 , @entity1369 and adrenocorticotrophic hormone concentrations were increased during percutaneous nephrolithotomy in both groups, but the increase was greater in Group S (P < 0.05). CONCLUSIONS: In the @entity2614 group, the concentrations of @entity916 , @entity1369 and adrenocorticotrophic hormone were significantly higher after 15 min of irrigation compared with the total intravenous anaesthesia group. Although the clinical significance of this difference was not clear, these changes should be considered in certain @entity1 groups.

Comparison of the effects of XXXX and total intravenous anaesthesia in percutaneous nephrolithotomy.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity1369 :: ('MESH:D000450', 'Chemical') :: ['aldosterone'] @entity680 :: ('MESH:D015760', 'Chemical') :: ['alfentanil'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity2614 :: ('MESH:C009250', 'Chemical') :: ['sevoflurane', 'Sevoflurane'] @entity916 :: ('5972', 'Gene') :: ['renin']
@entity2614 :: (MESH:C009250,Chemical) :: ['sevoflurane']
