AIM: To report the histologic findings on Whipple resection specimens and thus determine the extent and @entity189 of ampullary region and head of pancreas in our population. SETTING: Section of Histopathology, Department of Pathology, Aga Khan University Hospital (AKUH), Karachi, Pakistan. MATERIALS AND METHODS: A case series of 311 consecutive Whipple resection specimens received between January 1,2003 and December 31, 2014. Specimens processed for histologic sections and representative sections submitted and histologically examined as per established and standard protocols. All relevant @entity5 parameters including histologic type, histologic grade, pathologic T and N stage and @entity5 size were assessed. Epidemiologic data were also recorded. All findings were analysed using SPSS 19.0 software. RESULTS: @entity189 were much more common than @entity189 of the head of the pancreas, especially in males, with an average age of 53 years. Mean @entity5 size was 2.5 cms, over 54% were well differentiated. A large majority were pT2 or @entity1803 and N0. @entity189 of @entity9451 were also more common in males, mean age was 55 years, mean @entity5 size was 3.5cms, and over 65% were moderately differentiated. The majority were T2 or T3 and @entity3121 . Prognostically, significant statistical correlation was seen with @entity5 grade and pathologic T and N stage (p values statistically significant). However, @entity5 size was not statistically significant. CONCLUSIONS: @entity189 are more common compared to @entity3123 . Majority of @entity189 were well differentiated while majority of @entity3123 were moderately differentiated. Large majority of both types of cases were pT2 or T3. @entity5 grade and pathologic T and N stage are significantly related to prognosis in @entity15449 @entity1 with ampullary and @entity788 .

Epidemiologic Data, Tumor Size, Histologic Tumor Type and Grade, Pathologic Staging and Follow Up in Cancers of the Ampullary Region and Head of Pancreas in 311 Whipple Resection Specimens of XXXX @entity1 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3123 :: ('MESH:C562463', 'Disease') :: ['pancreatic carcinomas'] @entity1803 :: ('7694', 'Gene') :: ['pT3'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic cancers'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Histologic tumor'] @entity9451 :: ('MESH:D010195', 'Disease') :: ['pancreatic head'] @entity189 :: ('MESH:D002277', 'Disease') :: ['Ampullary (periampullary) carcinomas', 'carcinomas', 'Carcinomas', 'ampullary carcinomas', 'Ampullary carcinomas', 'spread of carcinomas'] @entity15449 :: ('MESH:C567551', 'Disease') :: ['Pakistani'] @entity3121 :: ('5270', 'Gene') :: ['pN1']
@entity15449 :: (MESH:C567551,Disease) :: ['Pakistani']
