OBJECTIVE: To systematically review the efficacy of multicomponent treatment of @entity239 ( @entity239 ). METHODS: We screened Medline, PsychINFO, Scopus, and the Cochrane Library (through December 2007), as well as reference sections of original studies, reviews, and evidence-based guidelines. Randomized controlled trials (RCTs) on the multicomponent treatment (at least 1 educational or other psychological therapy with at least 1 exercise therapy) of @entity239 were analyzed. RESULTS: We included 9 (of 14) RCTs with 1,119 subjects (median treatment time 24 hours) in the meta-analysis. Effects were summarized using standardized mean differences (SMDs) or @entity353 ( @entity353 ). There was strong evidence that multicomponent treatment reduces @entity158 ( @entity7126 -0.37; 95% confidence interval [95% CI] -0.62, -0.13), fatigue (WMD -0.85; 95% CI -1.50, -0.20), @entity308 ( @entity7126 -0.67; 95% CI -1.08, -0.26), and limitations to health-related quality of life (HRQOL) ( @entity7126 -0.59; 95% CI -0.90, -0.27) and improves self-efficacy @entity158 ( @entity7126 0.54; 95% CI 0.26, 0.82) and physical fitness ( @entity7126 0.30; 95% CI 0.02, 0.57) at posttreatment. There was no evidence of its efficacy on @entity2531 , @entity308 , HRQOL, or self-efficacy @entity158 in the long term. There was strong evidence that positive effects on physical fitness ( @entity7126 0.30; 95% CI 0.09, 0.51) can be maintained in the long term (median followup 7 months). CONCLUSIONS: There is strong evidence that multicomponent treatment has beneficial short-term effects on the key symptoms of @entity239 . Strategies to maintain the benefits of multicomponent treatment in the long term need to be developed.

Efficacy of multicomponent treatment in XXXX : a meta-analysis of randomized controlled clinical trials.

@entity308 :: ('MESH:D003866', 'Disease') :: ['depressive symptoms'] @entity239 :: ('MESH:D005356', 'Disease') :: ['fibromyalgia syndrome', 'FMS'] @entity353 :: ('MESH:D015431', 'Disease') :: ['WMDs', 'weighted mean differences'] @entity7126 :: ('MESH:C537501', 'Disease') :: ['SMD'] @entity2531 :: ('MESH:D013001', 'Disease') :: ['pain, fatigue, sleep disturbances'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity239 :: (MESH:D005356,Disease) :: ['fibromyalgia syndrome']
