Although antimicrobial resistance to @entity328 has been increased dramatically worldwide, there is limited information of pattern of susceptibility for this pathogen in Puerto Rico. Hospital-based surveillance for invasive @entity7706 was begun among 38 hospitals island-wide in Puerto Rico from January to December, 2001. One hundred ninety-two cases of invasive @entity66 were identified. Of the 177 isolates available for susceptibility testing, 50.3% were susceptible to @entity114 and 49.7% were nonsusceptible (intermediate (I) and resistance (R)) (19.2% I, 30.5% R). Resistance was documented for expanded spectrum cephalosporins and @entity7187 . All isolates were susceptible to @entity2176 . @entity6 , @entity65 , smoking and @entity565 were the most common risk factors associated with invasive @entity66 of the adult population. @entity565 was the most common disease in the pediatric population with a fatality rate of 21%. There was no increased mortality detected among @entity1 infected with penicillin resistant strains. Most of the isolates serotypes are represented in the 23-valent polysaccharide vaccine (78%) and 7-valent conjugate vaccine (62%). @entity114 -resistant isolates (47%) were 14, 19F, 6B, 6A, 9V, 23F, 19A and 35B serotype. Our data indicated a high prevalence for drug-resistant strains of @entity2260 in Puerto Rico. Continue surveillance for this common but serious pathogen is needed. Asthma is an important risk factor for @entity66 . The pneumococcal vaccine should be recommended for all age groups with this risk factor.

A multicenter hospital surveillance of invasive XXXX , Puerto Rico, 2001.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2176 :: ('MESH:D014640', 'Chemical') :: ['vancomycin'] @entity7706 :: ('MESH:D011008', 'Disease') :: ['pneumococcal infections'] @entity66 :: ('MESH:D004194', 'Disease') :: ['pneumococcal disease'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes'] @entity114 :: ('MESH:D010406', 'Chemical') :: ['Penicillin', 'penicillin'] @entity565 :: ('MESH:D001249', 'Disease') :: ['Bronchial asthma', 'bronchial asthma'] @entity2260 :: ('2104', 'Species') :: ['S. pneumoniae'] @entity7187 :: ('MESH:D018942', 'Chemical') :: ['macrolides'] @entity328 :: ('1313', 'Species') :: ['Streptococcus pneumoniae'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease']
@entity328 :: (1313,Species) :: ['Streptococcus pneumoniae']
