PURPOSE: The aim of this study was to evaluate the image quality of ultra-low-dose computed tomography (ULDCT) and its diagnostic performance in making a specific diagnosis of @entity55 in febrile neutropenic @entity1 with @entity1583 . MATERIALS AND METHODS: ULDCT was performed prospectively in 207 febrile neutropenic @entity1 with @entity1583 . Three observers independently recorded the presence of lung parenchymal abnormality, and also indicated the cause of the lung parenchymal abnormality between infectious and noninfectious causes. If infectious @entity55 was considered the cause of @entity358 , they noted the two most appropriate diagnoses among four infectious conditions, including fungal, bacterial, viral, and @entity10592 . Sensitivity for correct diagnoses and receiver operating characteristic (ROC) curve analysis for evaluation of diagnostic accuracy were calculated. Interobserver agreements were determined using intraclass correlation coefficient. RESULTS: Of 207 @entity1 , 139 (67%) had @entity55 , 12 had noninfectious @entity358 , and 56 had no remarkable chest computed tomography (CT) (20 with extrathoracic fever focus and 36 with no specific disease). Mean radiation expose dose of ULDCT was 0.60  0.15 @entity2073 . Each observer regarded low-dose CT scans as unacceptable in only four (1.9%), one (0.5%), and three (1.5%) cases of ULDCTs. Sensitivity and area under the ROC curve in making a specific @entity55 diagnosis were 63.0%, 0.65 for reader 1; 63.0%, 0.61 for reader 2; and 65.0%, 0.62 for reader 3; respectively. CONCLUSION: ULDCT, with a sub- @entity2073 radiation dose and acceptable image quality, provides ready and reasonably acceptable diagnostic information for @entity358 in febrile neutropenic @entity1 with @entity1583 .

Ultra-Low-Dose Chest CT in @entity1 with Neutropenic Fever and XXXX : Image Quality and Its Diagnostic Performance.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity10592 :: ('MESH:D011020', 'Disease') :: ['Pneumocystis pneumonia'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung disease', 'pulmonary infection', 'lung abnormalities'] @entity2073 :: ('10821', 'Species') :: ['mSv'] @entity1583 :: ('MESH:D019337', 'Disease') :: ['hematological malignancy', 'hematologic malignancy']
@entity1583 :: (MESH:D019337,Disease) :: ['Hematologic Malignancy']
