BACKGROUND: The left ventricular reverse remodeling (LVRR) in @entity1000 ( @entity384 ) and the treatment with @entity1405 in @entity1 with severe @entity712 remain poorly understood. METHODS: We reviewed the medical records of 5 @entity1 around 12 months old referred to our hospital with severe @entity712 due to @entity384 . Increased left ventricular fractional shortening (LVFS) by more than 10% and the percent of normal of left ventricular end-diastolic dimension (%LVDd) less than 120% were defined as LVRR in this study. RESULTS: @entity384 onset ranged from 8 to 16 months. Initial treatment of their @entity712 was successful in all 5 but 4 @entity1 relapsed despite the usual dose of @entity1405 (induction 0.02-maintenance 0.4mg/kg/day), and developed worsening @entity712 . @entity3876 ( @entity3876 ) levels which increased again after the acute treatment had fallen subsequent to discontinuing or decreasing @entity1405 . Over 24 months, LVFS had increased from 11  2% (mean  SD) to 34  5% (p<0.05), and %LVDd decreased from 149  27% to 108  11% (p<0.05). CONCLUSIONS: LVRR was found at 2 years after the onset of @entity384 . Usual dose induction of @entity1405 therapy can sometimes worsen @entity712 after successful initial conventional treatment for the @entity712 in @entity384 . Close control of @entity1405 treatment may determine the prognosis of infantile @entity384 around 12 months old. It is prudent to increase low-dose @entity1405 slowly corresponding with the @entity3876 level.

Left ventricular reverse remodeling with XXXX and pitfalls of @entity1405 therapy.

@entity1 :: ('9606', 'Species') :: ['patients', 'infants'] @entity712 :: ('MESH:D006333', 'Disease') :: ['acute heart failure', 'heart failure'] @entity384 :: ('MESH:D002311', 'Disease') :: ['DCM'] @entity3876 :: ('4879', 'Gene') :: ['BNP', 'Brain natriuretic peptide'] @entity1405 :: ('MESH:C043211', 'Chemical') :: ['carvedilol'] @entity1000 :: ('MESH:C536277', 'Disease') :: ['idiopathic dilated cardiomyopathy']
@entity384 :: (MESH:D002311,Disease) :: ['infantile dilated cardiomyopathy']
