We retrospectively analyzed outcome and risk factors of developing @entity10395 ( @entity10395 ) in 100 @entity1 with @entity6 who underwent a simultaneous @entity8 (SPK) transplantation. @entity1 who developed @entity10395 after SPK transplantation had significantly higher mortality (56% vs. 18%) and more frequently graft failure (44% vs. 13%). Recipients with @entity10395 also experienced acute rejections more frequently (78% vs. 41%). They furthermore had higher pre-transplant values of HbA1c , received @entity205 and @entity500 more often, and had significantly higher cumulative @entity228 use. @entity1 transplanted in an earlier era (1992-1998) received @entity205 and @entity500 more often and had a significantly higher cumulative corticosteroid use with the higher prevalence of @entity10395 . Conversely, @entity1 with @entity6 transplanted more recently (1999-2012) received lower doses of @entity288 as part of their @entity1140 -based immunosuppressive therapy, resulting in fewer @entity10395 attacks. In conclusion, development of @entity10395 after SPK is associated with poor @entity1 and graft outcome. Poor pre-transplant diabetic control and the use of high-dose @entity288 are risk factors for the development of @entity10395 . We recommend reduction in or even total avoidance of @entity288 after SPK transplantation. Given the importance of the diagnosis of @entity10395 on outcome, a systematic examination of SPK @entity1 ' feet is recommended.

Charcot neuroarthropathy after simultaneous XXXX transplantation: risk factors, prevalence, and outcome.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity8 :: ('MESH:D007674', 'Disease') :: ['pancreas-kidney'] @entity6 :: ('MESH:D003920', 'Disease') :: ['type 1 diabetes mellitus', 'diabetes'] @entity500 :: ('MESH:D001379', 'Chemical') :: ['azathioprine'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['corticosteroid'] @entity205 :: ('MESH:D016572', 'Chemical') :: ['cyclosporine'] @entity1140 :: ('MESH:D016559', 'Chemical') :: ['tacrolimus'] @entity10395 :: ('MESH:D005534', 'Disease') :: ['CF', 'Charcot foot'] @entity288 :: ('MESH:D000305', 'Chemical') :: ['corticosteroids']
@entity8 :: (MESH:D007674,Disease) :: ['pancreas-kidney']
