BACKGROUND: The effectiveness of surveillance for @entity157 ( @entity157 ) using ultrasound (US) in North America has been questioned due to the predominance of @entity1 of Caucasian ethnicity and larger body habitus. OBJECTIVE: To determine the effectiveness of US surveillance for @entity157 in a Canadian hepatobiliary centre and to identify independent variables associated with early @entity5 (s). METHODS: A retrospective review of @entity1 with first @entity157 in a US surveillance population at the authors' hospital yielded 201 @entity1 (over a 10.5-year period). @entity1 were categorized into three groups: regular surveillance (frequency of surveillance  <=12 months [n=109]); irregular surveillance (frequency of surveillance >12 months [n=38]); or first surveillance ( @entity5 detected on first scan [n=54]). The Milan criteria for transplantation and Barcelona Clinic @entity96 (BCLC) staging system were used as outcome measures. Effective surveillance was defined as @entity5 detection within Milan criteria or curative BCLC stages 0 and A; its association with multiple @entity1 - and disease-related variables was tested. RESULTS: When using the Milan criteria as outcome, 84 of 109 (77%) regular surveillance @entity1 , 23 of 38 (61%) irregular surveillance @entity1 and 40 of 54 (74%) first surveillance @entity1 had @entity5 meeting the transplantation criteria. The difference between regular and irregular surveillance was statistically significant (P=0.03). When using the BCLC staging system, 87 of 109 (80%) regular surveillance @entity1 , 26 of 38 (68%) irregular surveillance @entity1 and 41 of 54 (76%) first surveillance @entity1 had their @entity5 detected in BCLC curative stages (0 and A; P=0.11). Regular surveillance was the only variable significantly associated with @entity5 (s) within the Milan criteria (OR 2.76 [95% CI 1.10 to 6.88]). @entity5 detected more recently were more likely to be <2 cm in size (BCLC stage 0; OR 2.38 [95% CI 1.07 to 5.31]). CONCLUSION: A high rate of @entity157 surveillance success was achieved using US alone when performed regularly in a specialized hepatobiliary centre.

The effectiveness of ultrasound surveillance for XXXX in a Canadian centre and determinants of its success.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Tumours', 'detection of tumour', 'tumours', 'tumour'] @entity96 :: ('MESH:D008113', 'Disease') :: ['Liver Cancer']
@entity157 :: (MESH:D006528,Disease) :: ['hepatocellular carcinoma']
