BACKGROUND: @entity1086 ( @entity1086 ) has the propensity to fail at loco-regional (LR) and distant sites despite aggressive radical surgery. Adjuvant therapy in the form of radiotherapy (RT), systemic @entity7730 ( @entity7730 ) and chemoradiation (CRT) is the usual practice. Due to rarity of this disease, there is limited evidence to suggest the type of adjuvant treatment which should be offered to the @entity1 . AIM: The study was conducted to evaluate the impact of adjuvant treatment on curatively resected @entity1086 @entity1 . SETTINGS AND DESIGN: Histological proven @entity1 of @entity1086 registered between June, 2008 and July, 2014 were identified from our hospital database and retrospective analysis was done. MATERIALS AND METHODS: @entity1 of @entity1086 who had curative resection followed by adjuvant treatment as RT alone, @entity7730 alone or CRT were included in the study. STATISTICAL ANALYSIS: Adverse prognostic factors and the effect of adjuvant treatment on overall survival (OS) and disease free survival (DFS) were evaluated using Cox Regression Method and Kaplan Meier plot. RESULTS: We identified 33 @entity1 of which 23 were @entity34 (Early disease) and the remaining 10 were @entity5 ( @entity1442 ). All except one @entity1 had @entity420 . A total of 5 @entity1 were treated with RT alone while 16 @entity1 received @entity7730 alone. The remaining 12 @entity1 were treated with CRT. Median follow-up period was 8.5 months. At analysis 4 were alive while the remaining 29 were dead due to disease. With regard to "Early disease" @entity1 who had RT alone, @entity7730 alone and CRT, the median OS was 22.3, 10.3 and 15.2 months respectively (p = .440). Cohort of @entity1 with " @entity1442 " who were treated with @entity7730 alone and CRT the median OS was 7.5 and 7.0 months respectively (p = .643). On multivariate analysis none of the prognostic factors had an adverse impact on survival. CONCLUSION: The impact of adjuvant treatment in the form of RT, @entity7730 or CRT after curative resection in @entity1086 @entity1 was seen in terms of improved survival but was not statistically significant.

Impact of Adjuvant Therapy on Survival in Curatively Resected XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Stage III or IV disease'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['Advanced disease'] @entity7730 :: ('MESH:D064146', 'Disease') :: ['CT', 'chemotherapy'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma'] @entity1086 :: ('MESH:D005706', 'Disease') :: ['Gallbladder carcinoma', 'GBC'] @entity34 :: ('MESH:D016609', 'Disease') :: ['Stage I or II disease']
@entity1086 :: (MESH:D005706,Disease) :: ['Gallbladder Carcinoma']
