BACKGROUND: To compare the right and left transthoracic approach on the post-operative survival of @entity1 with lymph node-negative @entity1721 . METHODS: Six hundred and ninety-five @entity418 @entity1 who underwent esophagectomy between 1990 and 2005 were retrospectively enrolled in the present study and were confirmed by histology to be of no lymph node @entity3 . Those who had received neoadjuvant chemotherapy or radiotherapy were excluded from the study. @entity1 were divided into two groups, the left (n   =   545) and right (n   =   150) transthoracic groups. The follow-up duration ranged from 1 to 20  years with a mean of 7  years. Kaplan-Meier and univariate and multivariate Cox proportional hazards were used for analysis. RESULTS: 3- and 5-year CSS rates were 62.0  % and 44.0  % in the left group, while the corresponding figures in the right group were 56.0  % and 40.0  %(P   <   0.05). The overall survival for the two groups was significantly different (P   =   0.045). Survival analyses were stratified by stages, which found that the favorable survival advantage was not present. When the survival curves were stratified by @entity5 locations, a significant difference was not revealed. Surgical approaches were regarded as one of the prognostic factors in the univariate analysis (P   =   0.019). However, this significance could not be confirmed in multivariate Cox regression analysis (P   =   0.193). CONCLUSIONS: The left transthoracic approach is superior in some aspects to the right transthoracic approach regarding surgical and oncological outcomes in the treatment of lymph node negative @entity418 .

Right versus left transthoracic approach for lymph node-negative XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1721 :: ('MESH:C562729', 'Disease') :: ['esophageal squamous cell carcinoma'] @entity418 :: ('MESH:D004938', 'Disease') :: ['ESCC'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity1721 :: (MESH:C562729,Disease) :: ['esophageal squamous cell carcinoma']
