We investigated temperature regulation during anesthesia and postoperative shivering in chronically @entity308 patients given antidepressant drugs. We studied 35 @entity308 @entity1 and 35 control @entity1 who underwent orthopedic surgery. Tympanic membrane temperatures 60, 75, and 90 min after induction in the @entity308 group were significantly (P < 0.05) higher than those of the control group. There were no significant differences in mean skin temperature between the @entity308 and the control groups. Eight of 35 @entity1 in the @entity308 group and 2 of 35 @entity1 in the control group developed postanesthetic shivering. The incidence of shivering in the @entity308 group was significantly more frequent than that in the control group (P = 0.04). The tympanic membrane temperature of the @entity1 treated with @entity8991 tended to be higher than that of the @entity1 treated with @entity5081 . In conclusion, intraoperative @entity2332 in chronically @entity308 @entity1 was decreased. However, the incidence of shivering in @entity308 @entity1 was significantly more frequent. IMPLICATIONS: Thermoregulation in chronically @entity308 @entity1 is often altered. The alteration of body temperature is affected by @entity308 itself and by antidepressants. General anesthesia has an influence on thermoregulatory control. However, temperature regulation during anesthesia in chronically @entity308 @entity1 remains unclear.

Chronic treatment with antidepressants decreases intraoperative XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressed', 'depression'] @entity8991 :: ('MESH:D002997', 'Chemical') :: ['clomipramine'] @entity5081 :: ('MESH:D008376', 'Chemical') :: ['maprotiline'] @entity2332 :: ('MESH:D007035', 'Disease') :: ['core hypothermia']
@entity2332 :: (MESH:D007035,Disease) :: ['core hypothermia']
