OBJECTIVES: To assess the effectiveness of continuous @entity11399 acupressure as an adjunct to antiemetic drug therapy in the prevention and control of @entity390 and @entity391 in the first 24h after @entity583 ( @entity583 ). DESIGN: Partially randomised, partially blinded placebo-controlled, exploratory clinical study. SETTING: Coronary Care Unit, Torbay Hospital, Torquay, Devon. @entity1 : A total of 301 consecutive @entity1 (205 males, 96 females) admitted following acute @entity583 . INTERVENTION: The first 125 @entity1 recruited received no additional intervention. Subsequent @entity1 were randomised to receive either continuous @entity11399 acupressure or placebo acupressure. OUTCOME MEASURES: (1) Incidence of @entity583 , (2) severity of symptoms, (3) use of antiemetic drugs, over 24h. RESULTS: There were no significant differences between the groups for the whole 24-h treatment period. However, the @entity11399 acupressure group experienced significantly lower incidence of @entity1209 during the last 20h (18%), compared with the placebo (32%) or control (43%) groups (P<0.05). The severity of symptoms and the need for antiemetic drugs were also reduced in the acupressure group, but these differences were not statistically significant. CONCLUSIONS: Continuous 24-h @entity11399 acupressure therapy as an adjunct to standard antiemetic medication for @entity583 is feasible and is well accepted and tolerated by @entity1 . In view of its benefits, further studies are worthwhile using earlier onset of treatment.

Continuous @entity11399 wristband acupressure for relief of XXXX and @entity391 associated with @entity583 : a partially randomised, placebo-controlled trial.

@entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity11399 :: ('5125', 'Gene') :: ['PC6'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI', 'post-MI nausea and/or vomiting', 'post-MI nausea and vomiting'] @entity1209 :: ('MESH:D020250', 'Disease') :: ['nausea and/or vomiting']
@entity390 :: (MESH:D009325,Disease) :: ['nausea']
