To define the utility of fiberoptic bronchoscopy in the evaluation of immunocompromised @entity1 with @entity358 , we reviewed our experience between January 1980, and January 1983, with 50 such @entity1 with a wide variety of underlying diseases. Of these, 35 @entity1 underwent bronchoscopy, including brushings, alveolar lavage, and transbronchial biopsy, and 15 underwent open lung biopsy; 8 @entity1 underwent both procedures. All @entity1 with a nondiagnostic bronchoscopy either recovered without specific antibiotic therapy or underwent an open procedure. A diagnosis was made in 29 @entity1 (58%). An infectious process was found in 20 @entity1 (40%). A diagnosis was made bronchoscopically in 19 @entity1 including 18 @entity281 . Transbronchial biopsy was rarely diagnostic of infection when brushings were negative. For all diagnoses, bronchoscopy had a sensitivity of 76.9%. For all @entity358 , bronchoscopy had a sensitivity of 90%. Given a negative bronchoscopy, the probability that an infection was not present (i.e., predictive value negative) was 94.4%. Unfortunately, making a specific diagnosis did not appear to greatly improve survival. We conclude that in this setting: (1) fiberoptic bronchoscopy is an extremely sensitive procedure for diagnosing @entity358 , (2) bronchial brushings are as useful as transbronchial biopsies for diagnosing @entity281 , (3) these procedures are less useful for diagnosing noninfectious conditions, and (4) in the face of a negative bronchoscopic procedure, there is a very low probability that an infectious process will be found with an open biopsy.

The role of fiberoptic bronchoscopy in the evaluation of immunocompromised hosts with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['nonfungal infections', 'infections'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary infections', 'diffuse pulmonary infiltrates']
@entity358 :: (MESH:D008171,Disease) :: ['diffuse pulmonary infiltrates']
