OBJECTIVES: @entity1118 and long-term opioid use may lead to a persistent deficit in hedonic capacity, characterized by increased sensitivity to aversive states and insensitivity to natural rewards. Dispositional mindfulness has been linked with improved emotion regulation and @entity158 coping. The aim of the current study was to examine associations between dispositional mindfulness, hedonic capacity, and @entity158 -related interference in an opioid-using @entity1118 sample. METHODS: Data were obtained from a sample of 115 @entity1118 @entity1 on long-term opioid therapy (68% females, M age=48.3, SD=13.6) who completed the Five Facet Mindfulness Questionnaire (FFMQ), the Snaith-Hamilton Anhedonia and Pleasure Scale (SHAPS), the Brief Pain Inventory, and a psychiatric assessment of major @entity308 . Bivariate correlations, hierarchical multiple regression, and path analysis were used to determine whether dispositional mindfulness scores (FFMQ) predicted variance in hedonic capacity (SHAPS), and whether hedonic capacity mediated the association between mindfulness and @entity158 interference. RESULTS: We observed a significant positive correlation between dispositional mindfulness and hedonic capacity scores (r=0.33, P<0.001). Hierarchical regression indicated that after controlling for @entity158 interference and major @entity308 diagnosis, dispositional mindfulness explained a significant portion of variance in hedonic capacity (b=0.30, P<0.01). The association between dispositional mindfulness and @entity158 interference was mediated by hedonic capacity ( @entity69015 , @entity69016 ; 95% CI, -0.004 to -0.024, full model R=0.39). DISCUSSION: Findings indicate that dispositional mindfulness was associated with hedonic capacity among this @entity1118 sample. In light of this association, it is plausible that interventions that increase mindfulness may reduce @entity158 among opioid-using @entity1 by enhancing hedonic capacity.

Mindfulness is Associated With Increased Hedonic Capacity Among @entity1118 XXXX Receiving Extended Opioid Pharmacotherapy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive disorder', 'depression'] @entity69016 :: ('1056827(Tax:176280)', 'Gene') :: ['SE=0.005'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'pain-related impairment'] @entity69015 :: ('944771(Tax:511145)', 'Gene') :: ['b=-0.011'] @entity1118 :: ('MESH:D059350', 'Disease') :: ['Chronic pain', 'chronic pain']
@entity1 :: (9606,Species) :: ['Patients']
