PURPOSE: Monitoring distress assessment in @entity5 @entity1 during the treatment phase is a component of good quality care practice. Yet, there is a dearth of prospective studies examining distress. In an attempt to begin filling this gap and inform clinical practice, we conducted a prospective, longitudinal study examining changes in distress ( @entity148 , @entity308 , and problems in living) by age and gender and the roles of age and gender in predicting distress. METHODS: Newly diagnosed @entity5 @entity1 (N  =  548) were assessed at three time points during chemotherapy. Age and gender were identified on the first day of chemotherapy (T1); @entity148 , @entity308 , and problems in living were self-reported at T1, the planned midway point (T2), and the last day of chemotherapy (T3). RESULTS: At T1, 37 and 17% of @entity1 reported clinically significant levels of @entity148 and @entity308 , respectively. At T3, the prevalence was reduced to 4.6% for @entity148 and 5.1% for @entity308 (p  <  .001). @entity1 40-55  years, across all time points, reported greater @entity148 and practical problems than @entity1 >70  years (p  <  .03). Female @entity1 reported greater emotional, physical, and family problems than their male counterparts (p  <  .04). CONCLUSIONS: For most @entity1 , elevated levels of distress noted in the beginning of treatment subsided by the time of treatment completion. However, middle-aged and female @entity1 continued to report heightened distress. Evidence-based psychosocial intervention offered to at risk @entity1 during early phases of the treatment may provide distress relief and improve outcomes over the illness trajectory while preventing psychosocial and physical morbidity due to untreated chronic distress.

A prospective study of changes in XXXX , @entity308 , and problems in living during chemotherapy treatments: effects of age and gender.

@entity5 :: ('MESH:D009369', 'Disease') :: ['cancer', 'Brazilian cancer'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression']
@entity148 :: (MESH:D001008,Disease) :: ['anxiety']
