OBJECTIVE: The aim of this study was to examine medication adherence among outpatients with @entity161 in relation to their subjective quality of life and other sociodemographic, clinical and service related factors. METHODS: Three hundred and thirteen consecutive outpatient clinic attendees with a Diagnostic and Statistical Manual of @entity146 Fourth Edition (DSM-IV) diagnosis of @entity161 confirmed with the Structured Clinical Interview for Diagnosis were recruited for the study. Respondents were interviewed using a questionnaire evaluating sociodemographic, medication, illness and clinic attendance related variables. Medication adherence was assessed using the Morisky medication adherence questionnaire. @entity1 also completed the World Health Organization Quality of Life Scale-BREF questionnaire as a measure of their subjective quality of life, while severity of illness was measured using the Brief Psychiatric Rating Scale (BPRS). RESULTS: Overall, 40.3% of the respondents were medication nonadherent. Medication adherent respondents significantly reported their perceived social support as "good" (P=.006), took significantly fewer number of medications (P <=.001), had higher medication use recall scores (P <=.001), had lower total BPRS scores (P=.001) and were "very satisfied" with their outpatient care (P=.002). Independent predictors of medication nonadherence were BPRS score [odds ratio (OR)=1.08, 95% confidence interval (95% CI)=1.03-1.13], outpatient clinic default (OR= 4.97, 95% CI=2.59-9.53) and moderate satisfaction with outpatient care (OR=2.78, 95% CI=1.47-5.24). Medication nonadherence was significantly associated with lower scores on all domains and facets of quality of life. CONCLUSIONS: Medication nonadherence is common among outpatients with @entity161 and is associated with poor quality of life. Clinicians' awareness of the risk factors for medication nonadherence early in @entity1 ' management may significantly improve treatment outcomes, including @entity1 ' quality of life.

Medication adherence and quality of life among Nigerian outpatients with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Participants'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia'] @entity146 :: ('MESH:D001523', 'Disease') :: ['Mental Disorders']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
