BACKGROUND/AIMS: The purpose of this study was to determine the efficacy of intraoperative radiotherapy (IORT) for unresectable @entity3123 associated with hepatic or peritoneal @entity3 . METHODOLOGY: Between 1991 and 1994, 53 @entity1 with @entity3123 associated with hepatic or peritoneal @entity3 underwent surgery. Twenty-four of these @entity1 received IORT, while 29 received no radiation therapy. The efficacy of IORT on the postoperative survival and @entity158 relief for these @entity1 was retrospectively analyzed. RESULTS: Postoperative survival was lowest in the subgroup of @entity1 (n = 18) with both hepatic and peritoneal metastases, and this group did not benefit from IORT (IORT, n = 6; no IORT, n = 12) in terms of survival. Similarly, there was no significant difference in the survival rates between @entity1 undergoing IORT (n = 10) and @entity1 without IORT (n = 11) in the subgroup of @entity1 with hepatic @entity3 but without peritoneal @entity3 . However, @entity1 with peritoneal @entity3 but without hepatic @entity3 benefited significantly from IORT (IORT, n = 8; no IORT, n = 6) (p < 0.05). @entity158 relief following IORT was observed in 9 out of 10 @entity1 who had experienced @entity158 prior to surgery. CONCLUSION: @entity3123 associated with peritoneal @entity3 but without hepatic @entity3 can be palliated by IORT. In addition, @entity158 palliation in @entity1 who require gastrointestinal or biliary drainage can also be achieved by IORT.

Intraoperative radiotherapy for XXXX with hepatic or peritoneal metastases.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3123 :: ('MESH:C562463', 'Disease') :: ['pancreatic carcinoma', 'Pancreatic carcinoma'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity3123 :: (MESH:C562463,Disease) :: ['pancreatic carcinoma']
