BACKGROUND: The authors' earlier retrospective report of surgical complications after abdominal contouring surgery provided evidence that post-bariatric surgery @entity1 are at increased risk of developing wound complications compared with a normal population. This prospective pilot study was designed as a comparative analysis of both surgical and wound healing characteristics between massive @entity353 and normal @entity1 who present for abdominal contouring surgery. METHODS: Excisional wounds were created and @entity736 tubing was inserted during the preoperative period for later harvesting in @entity1 undergoing abdominal contouring following Roux-en-Y gastric bypass for @entity353 (n = 16) or abdominoplasty (n = 17). Wound fluids were sequentially collected from drains and subjected to matrix metalloproteinase (MMP) analysis. Standard postsurgical complications were documented. RESULTS: Surgical complications were more common in @entity353 @entity1 (47 percent) than in control @entity1 (25 percent). MMP analyses showed that @entity1495 levels remained significantly elevated at postoperative day 4 in @entity1 who subsequently experienced complications in either the @entity353 group (p = 0.02) or the control group (p = 0.03). Other parameters showed no significant differences between massive @entity353 @entity1 and controls. CONCLUSIONS: Although many markers were examined, the ratio of @entity1495 to albumin was the only predictor of postsurgical complications in any group. This lends further support to growing evidence that @entity1495 may be a useful biomarker of postsurgical complications. This pilot work showed no causal factors that explain the higher rates of postsurgical complications in the post-bariatric surgery @entity1 population. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, II.

The correlation of XXXX -to-albumin ratio in wound fluid with postsurgical complications after body contouring.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity736 :: ('CHEBI:53251', 'Chemical') :: ['polytetrafluoroethylene'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity1495 :: ('4318', 'Gene') :: ['MMP-9']
@entity1495 :: (4318,Gene) :: ['matrix metalloproteinase 9']
