BACKGROUND: Vascular access (VA) is the lifeline of hemodialysis @entity1 . Although the @entity4148 might be associated with @entity455 ( @entity455 ), it has never been addressed in previous studies. This study aimed to evaluate the predictive values of the heart rate variability (HRV) indices for long-term VA outcomes. METHODS: This retrospective study was conducted using a prospectively established cohort enrolling 175 adult chronic hemodialysis @entity1 (100 @entity1 , mean age 65.1    12.9 years) from June 2010 to August 2010. Each @entity1 received a series of HRV measurements at enrollment. After a 60-month follow-up period, we retrospectively reviewed all events and therapeutic procedures of the VAs which existed at the enrollment and during the follow-up period. RESULTS: During the 60-month follow-up period, 37 (26.8%) had @entity455 but 138 (73.2%) didn't. The values of most HRV indices were statistically increased during hemodialysis since initiation in the non- @entity455 group, but not in the @entity455 group. Among all @entity1 , the independent indicators for @entity455 included higher normalized high-frequency (nHF) activity [hazard ratio (HR) 1.04, p = 0.005], lower low-frequency/high-frequency (LF/HF) ratio (HR 0.80, p = 0.015), experience of urokinase therapy (HR 11.18, p = 0.002), percutaneous transluminal angioplasty (HR 2.88, p = 0.003) and surgical thrombectomy (HR 2.36, p = 0.035), as well as higher baseline serum @entity1011 (HR 1.07, p = 0.027) and @entity972 level (HR 1.58, p = 0.037). In subgroup analysis, a lower sympathetic activity indicated by lower LF/HF ratio was an independent indicator for @entity455 (HR 0.61, p = 0.03) for tunneled cuffed catheter, but conversely played a protective role against @entity455 (HR 1.27, p = 0.002) for @entity2548 . CONCLUSIONS: HRV is a useful tool for predicting long-term @entity455 among hemodialysis @entity1 .

Heart rate variability during hemodialysis is an indicator for long-term vascular access survival in uremic XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients', 'participant'] @entity455 :: ('MESH:D014652', 'Disease') :: ['VA failure', 'VAF'] @entity4148 :: ('MESH:D001342', 'Disease') :: ['autonomic nervous system'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity2548 :: ('MESH:D001164', 'Disease') :: ['arteriovenous fistula']
@entity1 :: (9606,Species) :: ['patients']
