1. Changes in plasma alpha 1-acid glycoprotein ( @entity14214 ) concentration and immune responses following @entity526 lipopolysaccharide (LPS) injection were studied in broiler @entity1573 . 2. Higher plasma @entity14214 concentrations were observed from 12 to 48 h after a single injection of LPS. 3. The highest concentration of plasma @entity14214 was observed on day 2 followed by a gradual decrease in chicks injected with 150 micrograms/kg body weight of LPS every day for 13 d. 4. Plasma @entity14214 concentration in chicks injected daily with LPS at 900 micrograms/kg body weight for 13 d increased on day 2, and decreased on day 4 to the concentration found before the injection. The concentration increased again on day 10. 5. Changes in plasma interleukin-1 (IL-1) like activity were similar to those in plasma @entity14214 concentration when LPS was injected daily at 900 micrograms/kg body weight for 3 d. 6. Responses of blood mononuclear cell (MNC) proliferation to mitogen or concanavalin A, (Con A), and pokeweed mitogen (PWM) were positively correlated with changes in plasma @entity14214 concentration. 7. The results suggest that plasma @entity14214 concentration could be used as a positive indicator of changes in blood MNC proliferation to a mitogen and in plasma IL-1 like activity.

Changes in plasma alpha 1-acid glycoprotein concentration and selected immune response in broiler @entity1573 injected with XXXX lipopolysaccharide.

@entity526 :: ('562', 'Species') :: ['Escherichia coli'] @entity1573 :: ('9031', 'Species') :: ['chickens'] @entity14214 :: ('CHEBI:73349', 'Chemical') :: ['AGP']
@entity526 :: (562,Species) :: ['Escherichia coli']
