OBJECTIVE: To describe a case series of @entity1776 in terms of clinical, histologic, and immunohistochemical features. METHOD AND MATERIALS: Nine cases of @entity1776 were described in terms of clinical features ( @entity1 sex and age, anatomical location, size, type, time to clinical progression, and lesion treatment), histologic features ( @entity39 , spindling, vesicular nuclei with large nucleoli, increased mitotic activity, high nuclear to cytoplasmic ratio, and pleomorphism) and immunohistochemical features using S-100, @entity469 , neurofilament protein, @entity2283 , and @entity4151 . RESULTS: Studied @entity1 were mostly @entity1 with a mean age of 32 years. Lesions arose as solitary nodules on the tongue, with size ranging from 0.1 to 3.0 cm. Mean time to evolution was 21.83 months. All cases were treated by surgical excision. Two cases were classified as atypical and seven as benign. All cases presented immunoreactivity for S-100, @entity469 , and @entity4151 , and there was no reactivity for @entity2283 and neurofilament protein. CONCLUSION: General practitioners should consider granular cell @entity5 during the differential diagnosis of nodular lesions on the tongue. Results suggest that histologic criteria may be used to distinguish between benign and atypical @entity1776 . Finally, analysis of the clinical profile and the use of immunohistochemical markers may facilitate diagnosis and clarify the histogenesis of these lesions.

XXXX : clinicopathologic and immunohistochemical study.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity2283 :: ('1674', 'Gene') :: ['desmin'] @entity1776 :: ('MESH:D016586', 'Disease') :: ['intraoral granular cell tumors'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity469 :: ('968', 'Gene') :: ['CD68'] @entity4151 :: ('3956', 'Gene') :: ['galectin-1']
@entity1776 :: (MESH:D016586,Disease) :: ['Intraoral granular cell tumors']
