PURPOSE: We developed a novel inflammation-based model ( @entity11989 ), which consisted of a neutrophil to lymphocyte ratio (NLR) and platelet count (PC), for assessing the prognostic role in @entity1 with metastatic @entity189 ( @entity189 ). MATERIALS AND METHODS: We performed a retrospective analysis of @entity1 with metastatic @entity189 who underwent systemic chemotherapy between January 1997 and December 2014 in Kaohsiung Chang Gung Memorial Hospital. The defined cutoff values for the NLR and PC were 3.0 and 400 * 103/ L, respectively. @entity1 were scored 1 for either an elevated NLR or PC, and 0 otherwise. The @entity11989 was calculated by summing the scores, ranging from 0 to 2. The primary endpoint was @entity1349 ( @entity1349 ) by using Kaplan-Meier analysis. Multivariate Cox regression analysis was used to identify the independent prognostic factors for @entity1349 . RESULTS: In total, 256 metastatic @entity189 @entity1 were enrolled. Univariate analysis revealed that @entity1 with either a high NLR or PC had a significantly shorter survival rate compared with those with a low NLR (P = .001) or PC (P < .0001). The median @entity1349 in @entity1 with @entity11989 0, 1, and 2 was 19.0, 12.8, and 9.3 months, respectively (P < .0001). Multivariate analysis revealed that @entity11989 , along with the histologic variant, liver @entity3 , age, and white cell count, was an independent factor facilitating @entity1349 prediction (hazard ratio 1.64, 95% confidence interval 1.20-2.24, P = .002). CONCLUSION: The NLR and PC are independent prognostic factors for @entity1349 in @entity1 with metastatic @entity189 . The @entity11989 model has excellent discriminant ability for @entity1349 .

Novel Inflammation-Based Prognostic Score for Predicting Survival in @entity1 with Metastatic XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity189 :: ('MESH:D002277', 'Disease') :: ['urothelial carcinoma', 'UC'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity11989 :: ('MESH:D009261', 'Disease') :: ['NPS'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity189 :: (MESH:D002277,Disease) :: ['Urothelial Carcinoma']
