High-dose chemotherapy with autologous SCT has become standard of care for @entity1 with relapsed aggressive @entity1893 ( @entity1893 ). To improve safety and efficacy of this treatment, new conditioning regimens are being developed. We retrospectively reviewed clinical data of @entity1 with relapsed @entity1893 treated at our institution with i.v. BU and CY (BU/CY) as conditioning regimen for autologous SCT between January 2000 and April 2005. We identified 43 @entity1 (24 @entity1 , 19 @entity1 , median age 50) with diffuse large @entity1892 (n=28), @entity706 (n=8), @entity1073 (n=4) and @entity3191 (n=3). Following salvage chemotherapy, there were 26 complete responses, 13 partial responses and 4 stable diseases. Median time to neutrophil and platelet recovery was 11 and 13.5 days, respectively. Treatment-related @entity137 included @entity390 / @entity391 , @entity294 and @entity33 . The 100-day mortality was 9%: @entity295 (n=1), @entity55 (n=1) and @entity5501 (n=2). Twenty-one @entity1 were followed until @entity204 and twenty-one surviving @entity1 were followed for a median of 29 months (range 0.4-76). Three-year estimates of event-free survival, progression-free survival and overall survival were 35, 39 and 43%, respectively. We conclude that i.v. BU/CY is a safe and effective conditioning regimen for autologous SCT in relapsed @entity1893 .

Autologous transplantation for relapsed XXXX using intravenous busulfan and cyclophosphamide as conditioning regimen: a single center experience.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicities'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity706 :: ('MESH:D008223', 'Disease') :: ['follicular lymphoma'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity3191 :: ('MESH:D016411', 'Disease') :: ['peripheral T-cell lymphoma'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity33 :: ('MESH:D052016', 'Disease') :: ['mucositis'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['B-cell lymphoma'] @entity1073 :: ('MESH:D020522', 'Disease') :: ['mantle cell lymphoma'] @entity5501 :: ('MESH:D006504', 'Disease') :: ['hepatic veno-occlusive disease'] @entity1893 :: ('MESH:D008228', 'Disease') :: ["non-Hodgkin's lymphoma", 'NHL'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1893 :: (MESH:D008228,Disease) :: ['non-Hodgkin's lymphoma']
