BACKGROUND: @entity309 ( @entity309 ) is an @entity792 that tends to be progressive and @entity102 . Previous studies showed that oxidative stress has a main role in pathology of @entity309 . The aim of this study was the easy elucidation of oxidative stress through pro-oxidant-antioxidant balance (PAB) in these @entity1 . METHOD: The sera of 130 @entity309 @entity1 and 130 age-matched healthy subjects (HS) were collected and the PAB was measured. According to the normal value of PAB in HS, the @entity1 group was divided into two groups; @entity1 with increased serum PAB and those with normal serum PAB values. In @entity1 with increased PAB value, the correlation of PAB value with @entity309 activity [(DAS28ESR)], biochemical parameters, and BMI were determined. RESULTS: Significantly higher serum PAB values were found in the whole @entity309 group of @entity1 (88.69  39.42 HK) in comparison to HS (53.57  25.10 HK), p  <= 0.05. There was no significant correlation between PAB values and @entity309 activity. In @entity1 with elevated serum PAB value; serum cholesterol, triglycerides and BMI were significantly higher in comparison to @entity1 with normal values. CONCLUSION: The PAB test can show the oxidative stress in @entity309 @entity1 . Further research should be done to determine the potency of the PAB assay as a tool for monitoring adverse effect of oxidative stress in @entity309 , as well as the effect of anti-oxidant therapies in the outcomes.

Pro-oxidant- Antioxidant Balance (PAB) in XXXX and its Relationship to Disease Activity.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmune disease'] @entity309 :: ('MESH:D001172', 'Disease') :: ['RA disease', 'Rheumatoid arthritis', 'RA'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic disease']
@entity309 :: (MESH:D001172,Disease) :: ['Rheumatoid Arthritis']
