UNASSIGNED: Recent studies show that higher-order appetitive neural circuitry may contribute to restricted @entity1278 (AN) and overeating in @entity1279 ( @entity1279 ). The purpose of this study was to determine whether sensitization effects might underlie pathologic eating behavior when a taste stimulus is administered repeatedly. @entity1278 ( @entity1278 , n=14) and @entity1279 (RBN, n=15) subjects were studied in order to avoid the confounding effects of altered nutritional state. Functional magnetic resonance imaging (fMRI) measured higher-order brain response to repeated tastes of @entity969 (caloric) and @entity12442 (non-caloric). To test sensitization, the neuronal response to the first and second administration was compared. @entity1278 @entity1 demonstrated a decreased sensitization to @entity969 in contrast to RBN @entity1 who displayed the opposite pattern, increased sensitization to @entity969 . However, the latter was not as pronounced as in healthy control @entity1 (n=13). While both @entity1277 subgroups showed increased sensitization to @entity12442 , the healthy controls revealed decreased sensitization. These findings could reflect on a neuronal level the high caloric intake of RBN during binges and the low energy intake for @entity1278 . @entity1278 seem to distinguish between high energy and low energy sweet stimuli while RBN do not.

Altered sensitization patterns to sweet food stimuli in @entity1 recovered from anorexia and XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity12442 :: ('MESH:C026285', 'Chemical') :: ['sucralose'] @entity1278 :: ('MESH:D000856', 'Disease') :: ['eating in anorexia nervosa', 'RAN', 'Recovered AN'] @entity969 :: ('MESH:D013395', 'Chemical') :: ['sucrose'] @entity1277 :: ('MESH:D001068', 'Disease') :: ['eating disorder'] @entity1279 :: ('MESH:D052018', 'Disease') :: ['bulimia nervosa', 'BN']
@entity1279 :: (MESH:D052018,Disease) :: ['bulimia nervosa']
