INTRODUCTION: Our study was designed to explore the hemodynamic effects of intravenous administration of @entity1289 -inhibitor @entity23288 in comparison with standard inotropic-vasodilator therapy. @entity1 with poor left ventricular function following coronary artery bypass (CABG) surgery were examined. MATERIALS AND METHODS: Thirty @entity1 with poor left ventricular function (EF<30%) following CABG surgery with use of cardiopulmonaly bypass were examined. Fourty @entity1 were control group. All @entity1 had complete invasive hemodynamic monitoring. The @entity1289 -inhibitor @entity23288 0.5 mg/h was administered intravenously via infusion pump. The following parameters were analyzed: arterial blood pressure, systemic vascular resistance, pulmonary vascular resistance, heart rate, cardiac output, cardiac index, left @entity64 work index and the level of mixed venous @entity26 saturation. RESULTS: The results of our study were as follows: Cardiac output, cardiac index and left @entity64 work index were significantly increased in comparison to the control group. Systemic arterial systolic pressure and pulmonary vascular resistance were decreased and there was no significant difference in systemic vascular resistance, mixed venous @entity26 saturation, heart rate and diastolic blood pressure in comparison to the control group. DISCUSSION: Our results pointed at very satisfactory hemodynamic effects of @entity23288 on " @entity1562 ", after CABG surgery. The @entity1289 inhibitors greatly reduce mortality in @entity1 in all stages of @entity712 , from asymptomatic dysfunction of the left ventricle to severe symptomatic stages. CONCLUSION: In prevention of @entity712 in @entity1 with impaired left ventricle function (LVEF<30%), who had undergone CABG surgery with use of cardiopulmonaly bypass, we achieved the best effects on the hemodynamics with parenteral administration of @entity23288 .

[Hemodynamic effects of intravenous administration of XXXX inhibitor in prevention of @entity712 following coronary artery bypass surgery].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['ventricular stroke'] @entity1289 :: ('1636', 'Gene') :: ['ACE'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity23288 :: ('MESH:C054501', 'Chemical') :: ['quinaprilat'] @entity1562 :: ('MESH:D017682', 'Disease') :: ['stunned myocardium']
@entity1289 :: (1636,Gene) :: ['ACE']
