Chemotherapy sensitivity has been identified as an important prognostic factor in @entity8 ( @entity8 ) for @entity1893 ( @entity1893 ). However, the effect of uniform salvage chemotherapy before @entity8 has not been studied prospectively. We examined whether the response to prospectively administered uniform salvage therapy ( @entity2879 , @entity229 , @entity1891 , @entity786 , @entity632 , and @entity3118 ) influenced the subsequent outcome of @entity8 in 28 @entity1 with relapsed or @entity1893 . After @entity8 , @entity1349 ( @entity1349 ) at 36 months is 49%, whereas @entity1349 ( @entity1349 ) is 32%. In Cox model analyses, the response to chemotherapy was the best predictor of @entity1349 (P = .0006) and @entity1349 (P = .0006) after @entity8 . Differentiating stable disease from progressive disease after salvage chemotherapy strengthened the association with survival. Among chemotherapy-sensitive @entity1 , the median @entity1349 and @entity1349 have not been reached. In @entity1 with stable disease, @entity1349 and @entity1349 at 24 months are 50% and 25%, respectively. In contrast, only 1 @entity1 with progressive disease during salvage therapy survived longer than 12 months. These prospective data confirm the favorable prognosis for chemotherapy-sensitive @entity1893 after @entity8 and suggest that chemotherapy resistance is not an absolute contraindication to @entity8 for @entity1893 @entity1 with stable disease during salvage therapy.

Efficacy of XXXX in chemotherapy-refractory @entity1893 .

@entity632 :: ('MESH:D004317', 'Chemical') :: ['doxorubicin'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity8 :: ('MESH:D007674', 'Disease') :: ['reduced-intensity allogeneic stem cell transplantation', 'RIST'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide'] @entity2879 :: ('MESH:D005047', 'Chemical') :: ['etoposide'] @entity3118 :: ('MESH:C024352', 'Chemical') :: ['fludarabine'] @entity1891 :: ('MESH:D014750', 'Chemical') :: ['vincristine'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['NHL', 'non-Hodgkin lymphoma', 'refractory NHL'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'EFS', 'event-free survival', 'overall survival']
@entity8 :: (MESH:D007674,Disease) :: ['reduced-intensity allogeneic stem cell transplantation']
