UNASSIGNED: Metastatic lesions in the large bowel are rare. A case of single symptomatic colonic @entity3 as first presentation of @entity2 ( @entity3975 ) is described. A 62-year-old male was admitted with @entity1142 and @entity548 . Colonoscopy revealed extrinsic compression at sigmoid colon, and microscopy suggested a secondary origin. Subsequent chest computed tomography confirmed a right perihilar mass invading posterior mediastinum, carina and esophagus, and also a second consolidation on right lower lobe and ipsilateral mediastinal and subcarinal lymph nodes. After pathologic evaluation of a transthoracic biopsy specimen, the diagnosis of pulmonary high-grade @entity3975 , stage IV (T4, N3, M1b - 7th ed. @entity2802 ), was established. Chemotherapy with carboplatin and paclitaxel was initiated, and disease progression occurred after two cycles with increasing @entity694 . Palliative surgery was rejected because of advanced stage, and the @entity1 was submitted to palliative pelvic radiotherapy. Second-line chemotherapy with gemcitabine was initiated, but clinical status worsened and the @entity1 died because of severe lung failure. Clinical, pathological and therapeutic aspects of this uncommon site of extrathoracic @entity3 are discussed, emphasizing the important contribution of special stains and immunohistochemistry to the diagnosis.

Single symptomatic colonic @entity3 as first presentation of a XXXX .

@entity1 :: ('9606', 'Species') :: ['patient'] @entity548 :: ('MESH:D006470', 'Disease') :: ['rectal bleeding'] @entity3975 :: ('MESH:D018277', 'Disease') :: ['MEC'] @entity2 :: ('MESH:D008175', 'Disease') :: ['pulmonary mucoepidermoid carcinoma'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colonic mass'] @entity2802 :: ('10178', 'Gene') :: ['TNM'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastatic disease'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation']
@entity2 :: (MESH:D008175,Disease) :: ['pulmonary mucoepidermoid carcinoma']
