OBJECTIVE: To determine which variables besides @entity1494 can help to predict the outcome of renal function in @entity1 with @entity340 ( @entity340 ). @entity1 AND METHODS: All 40 @entity1 with @entity340 in this retrospective study were diagnosed and began treatment in our hospital within the first 3 months of life, and have had >or= 5 years of follow-up. At the time of diagnosis, 33 were in @entity177 ( @entity177 ) and seven had normal renal function (RF). At the time of the study 16 were in @entity177 ( @entity177 ) and 24 had normal RF. We compared their RF (initial and during follow-up), @entity3025 ( @entity3025 ), @entity293 ( @entity293 ), @entity644 , @entity101 , renal echogenicity, final @entity1 age and initial management. RESULTS: The mean serum @entity1011 values before and after initial treatment were worse in @entity1 who developed @entity177 than in those who did not (P = 0.08); the mean glomerular filtrate rate (GFR) at 1 year old was 52 mL/min/1.73 m2 in the former and 102 in the latter (P < 0.001). @entity644 was present during the follow-up in 79% of @entity1 in @entity177 and in only 17% of those with normal RF. All @entity1 who developed @entity177 had echogenic renal changes while only 53% of the others had (P < 0.01). Other variables showed no statistically significant differences ( @entity3025 , @entity293 , @entity101 and final @entity1 age). Of 33 @entity1 in @entity177 at diagnosis, nine were treated by valve ablation and 24 by temporary pyelo-ureterostomy. The initial mean serum @entity1011 value was worse in the latter than in the former (20.8 vs 13.0 mg/L). However, at 1 year old the mean GFR was better in the latter than in the former (P < 0.05). These GFR differences persisted during the first years of life but had disappeared by the fifth. CONCLUSIONS: The most significant prognostic factor for the future development of @entity177 is the GFR at 1 year old. The onset of @entity644 during the follow-up is associated with a worse prognosis. Echogenic renal changes may help to identify those @entity8 that will develop @entity177 . Neonatal @entity1 in @entity177 who underwent pyelo-ureterostomy had better RF during the first years of life than those who underwent valve ablation.

XXXX : prognostic factors.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS', 'boys'] @entity644 :: ('MESH:D011507', 'Disease') :: ['Proteinuria', 'proteinuria'] @entity8 :: ('MESH:D007674', 'Disease') :: ['dysplastic kidneys'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1494 :: ('MESH:D001745', 'Disease') :: ['bladder dysfunction'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal insufficiency', 'chronic renal failure', 'RI', 'CRF'] @entity3025 :: ('MESH:D014718', 'Disease') :: ['VUR', 'vesico-ureteric reflux'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity340 :: ('MESH:D006349', 'Disease') :: ['posterior urethral valves', 'PUV'] @entity293 :: ('MESH:D014552', 'Disease') :: ['urinary tract infection', 'UTI']
@entity340 :: (MESH:D006349,Disease) :: ['Posterior urethral valves']
