Pharmacologic treatment patterns for @entity101 American Indians from 13 communities in Arizona, Oklahoma, South Dakota, and North Dakota were assessed. @entity1 (2254 @entity1 and 1384 @entity1 , aged 48 to 79 years) completed a clinical examination between July 1993 and December 1995. The mean of two blood pressure (BP) measurements and detailed medication histories were obtained. The observed prevalence of @entity101 was 46.7% (n=1698). In participants taking antihypertensive medications (n=1114), four principal drug classes were evaluated: diuretics, @entity460 channel blocking agents, beta-blocking agents, and @entity1289 ( @entity1289 ) inhibitors. Among treated @entity101 @entity1 , 71.4%, 24.6%, and 4.0% received one, two, and three medications, respectively. Among single drug regimens, @entity1289 inhibitors (n=340) were used most often (49.4%), with @entity460 channel blocking agents and diuretics accounting for 24.2% and 19.9%, respectively. Although multiple drug class therapies varied, the combination of a diuretic and @entity1289 inhibitor (n=120) accounted for 47.4% of dual therapy use. @entity101 control (SBP < 140 mm Hg, @entity13520 < 90 mm Hg) rates were highest for those on dual therapies (65.4%), followed by @entity1 on single (53.8%) and triple (43.6%) therapies. Among monotherapies, diuretics exhibited the best overall @entity101 control rate in both @entity6 (63.0%) and nondiabetics (68.0%), versus 47% to 61% for other remaining agents. The frequent use of @entity1289 inhibitors, used singly or in combination, reflects the high prevalence of @entity6 among American Indians. @entity1289 inhibitors, combined with diuretics, were particularly useful in achieving BP control in this population.

XXXX treatment patterns in American Indians: the strong heart study.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Participants', 'men'] @entity1289 :: ('1636', 'Gene') :: ['ACE', 'angiotensin-converting enzyme'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'Hypertension', 'hypertensive'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetics', 'diabetes'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity13520 :: ('1628', 'Gene') :: ['DBP']
@entity101 :: (MESH:D006973,Disease) :: ['Hypertension']
