BACKGROUND: @entity3101 has been used for many years in the treatment of @entity3100 . Increase in resistance to this medication has led to a search for new therapeutic alternatives. OBJECTIVE: Our purpose was to evaluate the therapeutic efficacy of @entity8974 in comparison with @entity3101 in the treatment of @entity3100 . METHODS: We performed a double-blind, randomized, prospective evaluation of 50 @entity1 with a clinical and mycologic diagnosis of @entity3100 . One group received 4 weeks of @entity8974 followed by 4 weeks of placebo. The other group received 8 weeks of @entity3101 . We evaluated 5 clinical parameters. Mycologic examinations were performed at baseline and at the end of weeks 8 and 12. RESULTS: @entity1 ' ages ranged from 1 to 14 years. Fifty-four percent were @entity1 and 46% were @entity1 . Mycologic examinations disclosed Trichophyton tonsurans in 74% of @entity1 and @entity14476 in 26%. At week 8, the @entity3101 -treated group showed a cure rate of 76%, and the @entity8974 -treated group 72%. At week 12, the efficacy of @entity3101 decreased to 44%, whereas the efficacy of @entity8974 was 76%. CONCLUSION: @entity8974 constitutes an alternative for the treatment of @entity3100 . Recurrences were less frequent. No significant side effects were reported.

Comparison of @entity8974 and XXXX in the treatment of @entity3100 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'girls', 'boys'] @entity8974 :: ('MESH:C041359', 'Chemical') :: ['Terbinafine', 'terbinafine'] @entity3101 :: ('MESH:D006118', 'Chemical') :: ['griseofulvin', 'Griseofulvin'] @entity3100 :: ('MESH:D014006', 'Disease') :: ['tinea capitis'] @entity14476 :: ('63405', 'Species') :: ['Microsporum canis']
@entity3101 :: (MESH:D006118,Chemical) :: ['griseofulvin']
