@entity355 is a distal metaplasia characterized by the transformation of squamous mucosa into columnar mucosa. This esophageal phenotype is a product not only of the chronic reflux of gastric acids, but also by microorganisms that colonize the oral cavity and stomach. Two classes of microbiota can be identified in @entity355 ; microbiota type I is associated with the normal esophagus and type II with an inflamed esophagus. The present study describes the gastric microbiota of a @entity1 with antral @entity3621 concomitant with @entity355 with @entity1534 . Gastric biopsies were obtained following the protocol of Sydney and following ethical practices. The isolates were cultivated under microaerophilic conditions on Columbia Agar supplemented with IsoVitaleX    and 7% sterile blood. Extracted DNA was sequenced using 454-GS and the results analyzed on the MG-RAST server. Gram negative isolates were found and bacteria resistant to @entity800 , @entity115 , @entity803 , @entity2929 , and @entity4581 . The phyla Bacteroidetes, Firmicutes, Fusobacteria and Proteobacteria, the genus @entity2868 and the species group @entity2868 were most abundant. Functionally, the metabolism of @entity3363 , @entity1522 , and to a lesser extent, the metabolism of cofactors and vitamins were most dominant, and of which the enzymes    -glucosidase (EC 3.2.1.21),    -galactosidase (EC 3.2.1.23) and    -N-acetylhexosaminidase (EC 3.2.1.52) were most dominant. The findings of this study, because they are of only one case may probably suggest a possible pathogenic role, previously undescribed for @entity2868 , associated with @entity1 @entity3621 when concomitant esophageal pathology exists.

Metagenomic analysis of the gastric microbiota cultivable from a XXXX with @entity3621 concomitant with @entity355 .

@entity1 :: ('9606', 'Species') :: ['human', 'patient'] @entity2868 :: ('817', 'Species') :: ['Bacteroides', 'Bacteroides fragilis'] @entity1522 :: ('CHEBI:33709', 'Chemical') :: ['amino acids'] @entity115 :: ('MESH:D000658', 'Chemical') :: ['amoxicillin'] @entity355 :: ('MESH:D001471', 'Disease') :: ["Barrett's esophagus", "Barrett's esophagus absent infection"] @entity4581 :: ('MESH:D017291', 'Chemical') :: ['clarithromycin'] @entity2929 :: ('MESH:D004917', 'Chemical') :: ['erythromycin'] @entity3621 :: ('MESH:D005756', 'Disease') :: ['gastritis'] @entity1534 :: ('210', 'Species') :: ['Helicobacter pylori'] @entity803 :: ('MESH:D013752', 'Chemical') :: ['tetracycline'] @entity800 :: ('MESH:D015242', 'Chemical') :: ['levofloxacin'] @entity3363 :: ('MESH:D002241', 'Chemical') :: ['carbohydrates']
@entity1 :: (9606,Species) :: ['patient']
