BACKGROUND: @entity2522 has been linked to adverse pregnancy outcome (APO). @entity6981 ( @entity6981 ) has been associated with APO. We assessed if bacterial counts in @entity6981 is associated with @entity2522 suggesting a systemic infectious susceptibilty. METHODS: Vaginal samples were collected from 180 @entity1 (mean age 29.4 years, SD +/- 6.8, range: 18 to 46), and at least six months after delivery, and assessed by semi-quantitative DNA-DNA checkerboard hybridization assay (74 bacterial species). @entity6981 was defined by Gram stain (Nugent criteria). @entity2522 was defined as bleeding on probing at >or= 20% of tooth sites. RESULTS: A Nugent score of 0-3 (normal vaginal microflora) was found in 83 @entity1 (46.1%), and a score of > 7 ( @entity6981 ) in 49 @entity1 (27.2%). @entity2522 was diagnosed in 114 @entity1 (63.3%). @entity1 with a diagnosis of @entity6981 were more likely to have @entity2522 (p = 0.01). Independent of gingival conditions, vaginal bacterial counts were higher (p < 0.001) for 38/74 species in @entity6981 + in comparison to @entity6981 - @entity1 . Counts of four lactobacilli species were higher in @entity6981 - @entity1 (p < 0.001). Independent of @entity6981 diagnosis, @entity1 with @entity2522 had higher counts of Prevotella bivia (p < 0.001), and Prevotella disiens (p < 0.001). P. bivia, P. disiens, @entity59539 and M. mulieris (all at the p < 0.01 level) were found at higher levels in the @entity6981 +/G+ group than in the @entity6981 +/G- group. The sum of bacterial load (74 species) was higher in the @entity6981 +/G+ group than in the @entity6981 +/G- group (p < 0.05). The highest odds ratio for the presence of bacteria in vaginal samples (> 1.0 x 104 cells) and a diagnosis of @entity2522 was 3.9 for P. bivia (95% CI 1.5-5.7, p < 0.001) and 3.6 for P. disiens (95%CI: 1.8-7.5, p < 0.001), and a diagnosis of @entity6981 for P. bivia (odds ratio: 5.3, 95%CI: 2.6 to 10.4, p < 0.001) and P. disiens (odds ratio: 4.4, 95% CI: 2.2 to 8.8, p < 0.001). CONCLUSION: Higher vaginal bacterial counts can be found in @entity1 with @entity6981 and @entity2522 in comparison to @entity1 with @entity6981 but not @entity2522 . P. bivia and P. disiens may be of specific significance in a relationship between vaginal and @entity281 .

The vaginal microflora in relation to XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Women'] @entity59539 :: ('2051', 'Species') :: ['M. curtisii'] @entity2522 :: ('MESH:D005891', 'Disease') :: ['gingivitis', 'Gingivitis'] @entity281 :: ('MESH:D007239', 'Disease') :: ['gingival infections'] @entity6981 :: ('MESH:D016585', 'Disease') :: ['Bacterial vaginosis', 'BV']
@entity2522 :: (MESH:D005891,Disease) :: ['gingivitis']
