OBJECTIVE: To study the relationship between 4 components of physical activity and the 12-year incidence of @entity922 ( @entity571 ) among older adults. METHODS: Longitudinal data from 1,678 @entity1 and @entity1 , ages 55-85 years, were collected in the Longitudinal Aging Study Amsterdam. Incident clinical knee @entity571 was defined by an algorithm using self-report and general practitioner data. Physical activity was assessed by a validated questionnaire from which 4 physical activity component scores were created: muscle strength, intensity, mechanical strain, and turning actions. Cox proportional hazards models were conducted to examine the relationship between these scores and incident knee @entity571 and reported as hazard ratios (HRs) with 95% confidence intervals (95% CIs). RESULTS: During 12 years of followup, 463 respondents (28%) developed clinical knee @entity571 . A high mechanical strain score (HR 1.43, 95% CI 1.15-1.77) and a low muscle strength score (HR 1.30, 95% CI 1.01-1.68) were associated with an increased risk of knee @entity571 after adjustment for age, sex, region of living, education, lifetime physical work demands, lifetime general physical activity, body mass index, current total physical activity level, and @entity308 . No association was observed in the intensity and turning actions components. The results were similar for @entity1 and @entity1 , and for @entity28 and nonobese respondents. CONCLUSION: Older adults who perform low muscle strength activities or activities causing high mechanical strain had an increased risk of clinical knee @entity571 . These results suggest that specific components of physical activity may influence the development of knee @entity571 .

Physical activity and incident XXXX in older adults.

@entity1 :: ('9606', 'Species') :: ['women', 'men'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity571 :: ('MESH:D010003', 'Disease') :: ['OA'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity922 :: ('MESH:D013568', 'Disease') :: ['clinical knee osteoarthritis']
@entity922 :: (MESH:D013568,Disease) :: ['clinical knee osteoarthritis']
