Fifty-three @entity1 who underwent a two-staged protocol of debridement and muscle flap coverage for chronic @entity4034 of the tibia between 1991 and 1996 were evaluated. All @entity1 underwent a thorough debridement of all nonviable tissue and bone at initial debridement. Multiple cultures were taken, including aerobic, anaerobic and fungal cultures from the pus, soft tissue, bone curettings and bone. All @entity1 were treated with open wound management and dressing changes. Between 2 to 7 days, median 4 days, all @entity1 underwent a second debridement with a complete set of identical cultures, and immediate soft tissue muscle transfer. There were 42 free vascularized and 11 local tissue transfers. The 53 @entity1 were classified according to the Cierny-Mader classification for chronic @entity4034 . Twenty-four @entity1 had @entity3480 , 10 @entity1 had @entity5 , nine @entity1 had @entity5 , eight @entity1 had Stage IVB @entity4034 , one @entity1 had Stage IA @entity4034 , and one @entity1 had @entity5 . All 53 @entity1 had positive cultures at the time of their initial debridement, and 14 of 53 (26%) had a positive culture at the time of the second debridement. Based on the results, it seems from a bacteriologic stand-point that the second debridement allows for the opportunity for redebridement and wound sterilization of organisms that still may be present.

Culture results in open wound treatment with muscle transfer for tibial XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity4034 :: ('MESH:D010019', 'Disease') :: ['osteomyelitis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Stage IIIA osteomyelitis', 'Stage IIIB osteomyelitis', 'Stage IIB osteomyelitis'] @entity3480 :: ('MESH:C538167', 'Disease') :: ['Stage IVA osteomyelitis']
@entity4034 :: (MESH:D010019,Disease) :: ['osteomyelitis']
