UNASSIGNED: @entity3925 is a once-daily oral anticoagulant currently indicated for the prevention of @entity64 and systemic @entity887 in @entity1 with nonvalvular @entity955 . It is also indicated for the prevention and treatment of @entity1211 . Despite the known advantages of @entity3925 over standard therapy, this treatment is not exempt from @entity548 . We present the case of a 51-year-old @entity1 with arterial @entity101 and paroxysmal @entity955 anticoagulated with @entity3925 20 mg o.d. @entity1 was admitted to the emergency department because of intense @entity490 , high temperature, @entity551 , @entity591 and a big @entity5 in the right abdominal area. The ultrasonic exam showed a big collection in the @entity1514 and abdominal area, compatible with @entity1410 . Due to clinical instability, urgent surgery was required. Based on the results of coagulation parameters (PT: 17.5 s), the time from the last @entity3925 dose was taken, and the @entity1 weight, nonactivated @entity18623 complex concentrate at a single dose of 1000 IU was administrated intravenously 1 h before the surgery. PT value decreased to normal value (13.5 s), and surgery was performed without any @entity548 complication. The management of @entity1 treated with @entity3925 who require urgent surgery is discussed in this report.

Reversal of XXXX anticoagulation by nonactivated prothrombin complex concentrate in urgent surgery.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'patient', 'Patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity18623 :: ('MESH:D011516', 'Chemical') :: ['prothrombin'] @entity1514 :: ('MESH:D013896', 'Disease') :: ['thoracic'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity591 :: ('MESH:D013610', 'Disease') :: ['tachycardia'] @entity887 :: ('MESH:D004617', 'Disease') :: ['embolism'] @entity3925 :: ('MESH:C503223', 'Chemical') :: ['Rivaroxaban', 'rivaroxaban'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous or pulmonary thromboembolism']
@entity3925 :: (MESH:C503223,Chemical) :: ['rivaroxaban']
