OBJECTIVE: To describe the distribution of thyroid-stimulating hormone (TSH) values and to estimate the prevalence of @entity1375 in the adult population of Castile and Le  n (Spain). METHOD: An observational study was conducted in an opportunistic sample of 45 primary care centers in Castile and Le  n. TSH was determined in @entity1 aged >= 35 years that attended a primary care physician and had a blood test for any reason. Confirmatory analysis included free @entity1955 and anti-thyroid peroxidase  antibody determination. RESULTS: A total of 3957 analyses were carried out, 63% in @entity1 . The mean age was 61.5 years. The median TSH value was 2.3  IU/mL (2.5  IU/mL in @entity1 and 2.1  IU/mL in @entity1 ), with a rising trend with age. TSH values were higher in undiagnosed or untreated @entity1375 than in @entity1 under treatment. The lowest levels were found in euthyroidism. The prevalence of @entity1375 was 9.2% (95%CI: 8.3-10.2), and @entity1375 was three times higher in @entity1 than in @entity1 (12.4% versus 3.7%). @entity1375 increased with age, reaching a peak of 16.9% in @entity1 aged 45 to 64 years. CONCLUSIONS: The prevalence of @entity1375 in our sample was high and in the upper limits of values found in previous studies. Proper diagnosis and treatment are important because of the risk of progression to @entity1375 and the association with @entity66 and other risk factors.

[Prevalence and clinical characteristics of XXXX in an opportunistic sample in the population of Castile-Le  n (Spain).]

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'people', 'men'] @entity1375 :: ('MESH:D007037', 'Disease') :: ['Hypothyroidism', 'subclinical hypothyroidism', 'hypothyroidism'] @entity1955 :: ('MESH:D013974', 'Chemical') :: ['thyroxine'] @entity66 :: ('MESH:D004194', 'Disease') :: ['multiple diseases']
@entity1375 :: (MESH:D007037,Disease) :: ['subclinical hypothyroidism']
