OBJECTIVE: To compare the long-term real-world outcomes of consecutive @entity1 with unprotected left main @entity453 (ULMCA) underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and coronary artery bypass grafting (CABG). METHODS: Consecutive @entity1 with ULMCA (defined as stenosis >=  50%) undergoing DES implantation or CABG between January 2003 to July 2009 in Beijing Anzhen Hospital were enrolled. The follow-up period extended through August 2013. The end points of the study were @entity204 , @entity204 , repeat revascularization, @entity583 ( @entity583 ), @entity64 , the composite of @entity204 , @entity583 or @entity64 and MACCE (major adverse cardiac and cerebrovascular events, the composite of @entity204 , @entity583 , @entity64 or repeat revascularization). RESULTS: From January 2003 to July 2009, 922 ULMCA @entity1 were enrolled in this study (465 PCI @entity1 , and 457 CABG @entity1 ). The median follow-up was 7.1 years (interquartile range 5.3 to 8.2 years). The crude relative risk was as follows: overall @entity204 rate (13.0% (41/465) vs. 22.1% (72/457), P = 0.009), @entity64 rate (5.8% (11/465) vs. CABG 18.9% (46/457), P < 0.001) were significantly lower whereas the rate of repeat revascularization (32.3% (110/465) vs. CABG 19.2% (58/457), P < 0.001) was significantly higher in PCI group than in CABG group. @entity583 rate was similar between PCI and CABG group (13.9% (33/465) vs. 6.7% (26/457), P = 0.196). MACCE rate was also similar between the 2 groups (42.9% (145/465) vs. 42.5% (142/457), P = 0.122). After multivariate adjusting, there was no significant difference in rates of @entity204 , @entity583 and a composite of serious outcomes ( @entity204 , @entity583 , or @entity64 ) between the 2 groups. Rates of MACCE were significantly higher in the PCI group (P = 0.009) due to increased rate of repeat revascularization (P < 0.001). However, @entity64 rate was still significantly higher in CABG group (P = 0.001) after multivariate adjusting. CONCLUSION: During a follow-up up to 8.2 years, the survival rate is similar between the PCI and the CABG group in @entity1 with @entity453 . The rate of repeat revascularization is significantly higher and @entity64 rate is significantly lower in the PCI group compared to CABG group.

[Long-term outcomes of @entity1 with unprotected left main XXXX post revascularization].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity453 :: ('MESH:D003324', 'Disease') :: ['ULMCA disease', 'coronary artery disease'] @entity204 :: ('MESH:D003643', 'Disease') :: ['cardiac death', 'death']
@entity453 :: (MESH:D003324,Disease) :: ['coronary artery disease']
