OBJECTIVE: To assess the frequency and significance of @entity37345 infection in type 1 @entity775 . MATERIAL AND METHODS: Serum specimens from 94 @entity1 with type 1 @entity775 were tested for @entity37345 RNA by reverse transcription and polymerase chain reaction. Serum samples from 50 normal subjects were also assessed. RESULTS: Three of the 94 specimens from @entity1 with @entity775 were positive for @entity37345 RNA in comparison with none of the 50 control samples (3% versus 0%; P = 0.5). Two @entity1 were seropositive after @entity548 and blood transfusion, including one @entity1 who clearly acquired the infection in this fashion. One @entity1 had no epidemiologic basis for his seropositivity. @entity646 was prolonged in all infected @entity1 (mean duration, 69 +/- 23 months; range, 36 to 113); however, no clinical features suggested a concurrent @entity1800 , and mortality was similar to that among the uninfected counterparts (33% versus 8%; P = 0.2). Liver transplantation was more common in the infected @entity1 (67% versus 9%; P = 0.03), but the duration of disease was also longer in these @entity1 (277 +/- 29 months versus 106 +/- 9 months; P = 0.0008). Clinical features and immediate responses to @entity228 therapy were similar in both groups. CONCLUSION: @entity37345 RNA is found infrequently in type 1 @entity775 , and @entity37345 is unlikely to be an important etiologic agent or prognostic determinant.

@entity37345 infection in type 1 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity646 :: ('MESH:D014766', 'Disease') :: ['Viremia'] @entity548 :: ('MESH:D006470', 'Disease') :: ['variceal hemorrhage'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['corticosteroid'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral infection'] @entity37345 :: ('54290', 'Species') :: ['GB virus-C'] @entity775 :: ('MESH:D019693', 'Disease') :: ['autoimmune hepatitis']
@entity775 :: (MESH:D019693,Disease) :: ['autoimmune hepatitis']
