Sham surgery is used as a control condition in neurosurgical clinical trials in @entity191 ( @entity191 ) but remains controversial. This study aimed to assess the perspective of @entity1 with @entity191 and the general public on the use of sham surgery controls. We surveyed consecutive @entity1 from a university-based neurology outpatient clinic and a community-based general internal medicine practice. Background information was provided regarding @entity191 and two possible methods of testing the efficacy of a novel gene transfer procedure, followed by questions that addressed @entity1 ' opinions related to the willingness to participate and permissibility of blinded and unblinded trial designs. Two hundred eighty-eight (57.6%) @entity1 returned surveys. @entity1 with @entity191 expressed less willingness to participate in the proposed gene transfer surgery trials. Unblinded studies received greater support, but a majority would still allow the use of sham surgery. Those in favor of sham surgery were more educated and more likely to use societal perspective rationales. @entity1 with @entity191 are more cautious about surgical research participation than @entity1 with non- @entity191 . Their policy views were similar to others', with a majority supporting the use of sham controls. Future research needs to determine whether eliciting more considered judgments of laypersons would reveal different levels of support for sham surgery.

Ethics of sham surgery: perspective of XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'Patients', 'patients'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease", 'PD']
@entity1 :: (9606,Species) :: ['patients']
