A 70-year-old @entity1 presented to us with the chief complaints of a generalized @entity1910 and a mass in the right clavicular region that he first noticed in the year 2012. Biopsy of the mass led to the diagnosis of cutaneous nodular mass-type @entity6494 ( @entity6494 ) in March 2013. Phototherapy was started, and the symptoms improved temporarily. However, in late June 2013, the serum @entity880 dehydrogenase (LDH) level increased to 358 IU/L, which was 1.6 times higher than the upper limit of the reference range; based on the findings, transformation of the disease to the acute type was diagnosed. The @entity1 was treated with 6 courses of @entity3726 therapy ( @entity786 , @entity632 , @entity1891 , and @entity617 ), which resulted in complete remission (CR). However, the @entity1910 recurred in late October 2013, and treatment with mogamulizumab was initiated. A total of 8 courses of mogamulizumab were administered, which resulted in CR. The @entity1910 and cutaneous nodular masses recurred again in January 2014, and a total of 8 courses of mogamulizumab were administered again starting in February 2014. However, the @entity1 's symptoms began to worsen gradually. Phototherapy was also initiated, but had to be discontinued due to the development of photosensitivity. Treatment with the combination of mogamulizumab and @entity2879 (25 mg/day for 21 days) was started in May 2014. The nodular mass rapidly decreased in size. The @entity1910 or cutaneous nodular mass had not recurred as of August 2014. Thus, combined therapy with mogamulizumab plus @entity2879 is considered to be effective for resolution of the cutaneous nodular masses in @entity1 with @entity6494 .

A case of post-mogamulizumab relapse of acute-type XXXX successfully treated with mogamulizumab and @entity2879 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'man'] @entity632 :: ('MESH:D004317', 'Chemical') :: ['doxorubicin'] @entity1910 :: ('MESH:D005076', 'Disease') :: ['rash'] @entity3726 :: ('1649', 'Gene') :: ['CHOP'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide'] @entity2879 :: ('MESH:D005047', 'Chemical') :: ['etoposide'] @entity6494 :: ('MESH:D015459', 'Disease') :: ['ATLL', 'adult T-cell leukemia/lymphoma'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity1891 :: ('MESH:D014750', 'Chemical') :: ['vincristine'] @entity617 :: ('MESH:D011239', 'Chemical') :: ['prednisolone']
@entity6494 :: (MESH:D015459,Disease) :: ['adult T-cell leukemia/lymphoma']
