Accumulating evidences indicate @entity5 plays a pivotal role in @entity105 . Systematic inflammatory response biomarkers are considered as potential prognostic factors for improving predictive accuracy in @entity14 ( @entity14 ). Preoperative neutrophil-to-lymphocyte ratio (NLR), derived neutrophil-to-lymphocyte ratio (d-NLR), platelet-to-lymphocyte ratio (PLR) and lymphocyte- to-monocyte ratio (LMR) were investigated and compared in 205 surgical @entity14 @entity1 . ROC curve was applied to determine thresholds for four biomarkers, and their prognostic values were assessed using Kaplan-Meier curve, univariate and multivariate COX regression models. Moreover, a number of risk factors were used to form nomograms for evaluating risk of survival, and Harrell's concordance index (c-index) was used to evaluate predictive accuracy. Results showed that elevated NLR was significantly associated with diminished @entity1349 ( @entity1349 ), @entity1349 ( @entity1349 ) and @entity5 -specific survival (CSS) in surgical @entity14 @entity1 . Moreover, multivariate COX analysis identified elevated NLR as an independent factor for poor @entity1349 (P  <  0.001, HR 2.52, 95  % CI 1.65-3.83), @entity1349 (P  <  0.001, HR 2.73, 95  % CI 1.74-4.29) and CSS (P  <  0.001, HR 2.77, 95  % CI 1.72-4.46). Additionally, predictive nomograms including NLR for @entity1349 , @entity1349 and CSS could be more effective in predicting @entity1349 (c-index: 0.810 vs. 0.656), @entity1349 (c-index: 0.809 vs. 0.690) and CSS (c-index: 0.802 vs. 0.688) in surgical @entity14 @entity1 , respectively. These findings indicate that preoperative elevated NLR can be considered as an independent prognostic biomarker for @entity1349 , @entity1349 and CSS. Nomograms containing NLR provide improved accuracy for predicting clinical outcomes in surgical @entity14 @entity1 under surgery resection.

The prognostic value of preoperative NLR, d-NLR, PLR and LMR for predicting clinical outcome in surgical XXXX @entity1 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer-triggered inflammation', 'cancer'] @entity14 :: ('MESH:D015179', 'Disease') :: ['CRC', 'colorectal cancer'] @entity105 :: ('MESH:D063646', 'Disease') :: ['carcinogenesis'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'RFS', 'recurrent-free survival', 'overall survival']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal cancer']
