OBJECTIVE: To evaluate the clinical efficacy of Negative Pressure Wound Therapy (NPWT) using Vacuum Assisted Closure (VAC) compared with Advanced Moist Wound Therapy (AMWT) to treat @entity6 Ulcer (DFU). STUDY DESIGN: Randomized control trial. PLACE AND DURATION OF STUDY: Surgical Department, Combined @entity580 (CMH) / @entity580 ( @entity580 ), Rawalpindi, from November 2010 to June 2012. METHODOLOGY: The study consisted of 278 @entity1 , with 139 @entity1 each in Group _#039;A_#039; and _#039;B_#039;, who were subjected to AMWTand NPWT, respectively. Wound was assessed digitally every week for 2 weeks. Wound dimension and surface area were determined using University of Texas Health Centre at San Antonio (UTHCSA) image tool version 3.0. Efficacies of AMWTand NPWTwere compared in terms of reduction in wound area over 2 weeks. RESULTS: Mean age of presentation in group Awas 55.88 _plusmn;10.97 years while in group B, it was 56.83 _plusmn;11.3 (p=0.48). Mean duration of @entity6 at presentation was 15.65 _plusmn;4.86 and 15.96 _plusmn;5.79 years in group Aand B, respectively (p=0.74). Majority of @entity1 had Wagner_#039;s grade 2 @entity1066 (82% in group Aand 87.8% in group B, p= 0.18). Initial wound size in group Awas 15.07 _plusmn;2.92 cm2and in group B 15.09 _plusmn;2.81 cm2(p = 0.95). Wound size measured after 2 weeks, treatment was in group A13.70 _plusmn;2.92 cm2 and in group B 11.53 _plusmn;2.78 cm2 (p < 0.001). Wound area reduction in both groups revealed statistically significant faster healing in group B as compared to group A(p < 0.001). CONCLUSION: NPWTusing VAC was more efficacious than AMWTin the management of @entity4760 .

Comparison of Negative Pressure Wound Therapy Using Vacuum-Assisted Closure with Advanced Moist Wound Therapy in the Treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes', 'Diabetic Foot'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer'] @entity580 :: ('MESH:D003428', 'Disease') :: ['Military Hospital', 'MH'] @entity4760 :: ('MESH:D017719', 'Disease') :: ['diabetic foot ulcers']
@entity4760 :: (MESH:D017719,Disease) :: ['Diabetic Foot Ulcers']
