OBJECTIVE: To evaluate the diagnosis, management and nasal endoscopic surgical outcome of nasopharyngeal granulomatous mass in post-radiation @entity189 ( @entity189 ) @entity1 . MATERIALS AND METHODS: A total of 23 cases of granulomatous mass after radiotherapy for @entity189 from 2008 to 2013 treated with nasal endoscopic surgery were retrospectively reviewed. RESULTS: Radiotherapy dose (p=0.036) and chemotherapy (p<0.001) correlated with the latency period after the treatment against @entity189 . The symptoms of the 23 @entity1 before the treatment were nonspecific including nasal obstruction, @entity3389 , @entity10 , @entity1415 , @entity393 . 12 @entity1 (52.2%) were misdiagnosed to be recurrence of @entity189 by imaging examination (CT/MRI). After the endoscopic surgery treatment, 18 @entity1 were disease free while the other 5 @entity1 had developed a recurrence. Four of those five recurrent @entity1 were cured with the repeated treatment. Histologic findings of granulation tissue with fibrin and inflammatory cells were found in all of the @entity1 . CONCLUSIONS: In situ granulomatous masses in post-radiation @entity189 @entity1 are very prone to be misdiagnosed as recurrence of @entity189 . Chemotherapy is a significant independent factor affecting latency period (p=0.029). The nasal endoscopic surgery is an effective therapy for post-radiation nasopharyngeal granuloma; surgery can not only alleviate symptoms, what is more important, but it also helps to confirm the diagnosis.

Nasopharyngeal granulomatous mass after radiotherapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1415 :: ('MESH:D004844', 'Disease') :: ['epistaxis'] @entity189 :: ('MESH:D002277', 'Disease') :: ['nasopharyngeal carcinoma', 'NPC'] @entity393 :: ('MESH:D034381', 'Disease') :: ['foreign body sensation and/or hearing impairment'] @entity3389 :: ('MESH:D019522', 'Disease') :: ['purulent discharge'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache']
@entity189 :: (MESH:D002277,Disease) :: ['nasopharyngeal carcinoma']
