Obesity is a well-known risk factor for postmenopausal @entity0 . In contrast, the relationship between @entity28 and stage of @entity0 at diagnosis is less clear. We hypothesized that increased breast size in @entity28 @entity1 may delay @entity0 . Thus, the purpose of our study was to examine whether there is an association between body mass and stage of @entity0 at diagnosis using hospital medical records. Newly diagnosed @entity0 cases (n = 966) in the Baltimore metropolitan area from 1991 to 1997 were included in our study. @entity1 information including age, ethnicity, weight, height and pathology data were obtained from hospital medical records. High body mass was significantly associated with late stage of @entity0 at diagnosis. @entity1 who were @entity28 (body mass index [BMI] > or = 27.3) were more likely to be at an advanced stage at diagnosis compared with @entity1 with a BMI of < 27.3 (multivariate-adjusted odds ratio [OR] 1.57, 95% confidence interval [CI] 1.15-2.14). The association between body mass and stage at diagnosis was stronger among @entity1 younger than 50 years (OR 2.34, 95% CI 1.34-4.08) compared with @entity1 50 years or older (OR 1.30, 95% CI 0.89-1.91). Our study suggests that higher body mass is associated with advanced stage of @entity0 at diagnosis. This finding may be of considerable concern, given the increasing prevalence of @entity28 in @entity1 in the United States and the poor prognosis associated with @entity5 .

Body mass and stage of XXXX at diagnosis.

@entity1 :: ('9606', 'Species') :: ['women', 'Women', 'Patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['late-stage tumors'] @entity0 :: ('MESH:D001943', 'Disease') :: ['discovery of breast tumors', 'breast cancer'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese', 'obesity']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
