Bone marrow transplantation and stem cell transplantation have become standard therapies offering potential cures for a number of @entity1583 and @entity1200 . @entity281 remains a life threatening complication after transplantation, contributes significantly to morbidity, and may necessitate admission to the ICU. It is estimated that between 20 and 40% of @entity1 receiving bone marrow transplant will require ICU admission in the initial posttransplantation phase. Historically, survival rates after admission to the ICU are dismal, particularly if mechanical ventilation is required for @entity1576 . Other organ involvement worsens the prognosis still further and has led to proposals for rationing or restricting access to critical care units and supportive measures. Recent studies have reported small but significant improvements in outcome after @entity3124 . Whether this improvement is a result of changes in levels of supportive care or a more defined @entity1 selection is uncertain. Moreover, risk factors identifying @entity1 who will benefit most from intensive support are poorly defined. However, it is generally accepted that @entity1576 requiring invasive mechanical ventilation is associated with a poor prognosis in this @entity1 group. Early involvement of intensivists in the management of @entity3124 in transplant recipients is likely to continue to improve survival in this group of @entity1 .

Severe XXXX after bone marrow transplantation.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity3124 :: ('MESH:D016638', 'Disease') :: ['critical illness'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Severe infection'] @entity1200 :: ('MESH:D007154', 'Disease') :: ['immunologic disorders'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory failure'] @entity1583 :: ('MESH:D019337', 'Disease') :: ['hematologic malignancies']
@entity281 :: (MESH:D007239,Disease) :: ['infections']
