AIMS: Decreased right ventricular function via deformation analysis has been noted in @entity1 with @entity1699 ( @entity1699 ) after the Norwood procedure. No data exist in @entity1699 @entity1 undergoing the hybrid procedure. The goal of this study was to evaluate right ventricular functional changes in @entity1699 @entity1 undergoing the hybrid procedure under steady-state conditions. METHODS AND RESULTS: Echocardiograms were prospectively obtained on @entity1 with @entity1699 before and after the hybrid procedure. Fractional area change, tricuspid inflow velocities, tissue Doppler imaging (TDI), and deformation analysis were performed. Paired Wilcoxon's signed rank or Student's t-test was used for analysis. P < 0.05 was considered significant. Twenty @entity1699 @entity1 were studied (10 males:10 females). Median age at the pre-hybrid echocardiogram was 3 (1-16) days, age at hybrid procedure was 5 (3-17) days, and age at post-hybrid echocardiogram was 10 (6-34). There were significant decreases in systolic function as measured by TDI and deformation analysis. There was no significant change in right ventricular fractional area change. Diastolic function was also noted to significantly decrease after the hybrid procedure. CONCLUSION: Systolic and diastolic functions decreased after the hybrid procedure despite the fact that @entity1 avoided cardiopulmonary bypass. These results are comparable with previous reports in @entity1699 @entity1 undergoing the Norwood procedure. Further studies are needed to determine if these echocardiographic changes have prognostic significance.

Changes in right ventricular function in neonates with XXXX before and after the hybrid procedure.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1699 :: ('MESH:D018636', 'Disease') :: ['hypoplastic left heart syndrome', 'HLHS']
@entity1699 :: (MESH:D018636,Disease) :: ['hypoplastic left heart syndrome']
