BACKGROUND: Previous published case series have suggested an association between the onset of @entity4401 in pregnancy and the risk of @entity1468 and gestational @entity101 . AIM: To evaluate the period of onset of @entity4401 in pregnancy and the associated risk of adverse maternal and perinatal events, including the @entity101 disorders of pregnancy. STUDY DESIGN: Case series study of consecutive female @entity1 . METHODS: @entity1 presenting with @entity4401 during pregnancy or the puerperium were identified by a hospital record review at five Canadian centres over 11 years. Information was abstracted about each @entity1 's medical and obstetrical history, period of onset of @entity4401 , and associated maternal complications, including @entity1468 and gestational @entity101 as well as @entity3152 and low @entity1 birth weight (<2500 g). These rates were compared to those previously described for the province of Ontario or for Canada. RESULTS: Forty-one @entity1 were identified. Mean onset of @entity4401 was 35.4 weeks gestation (SD 3.9). Nine (22.0%, 95%CI 10.8-35.7) were also diagnosed with @entity1468 and three (7.3%, 95%CI 1.4-17.1) with gestational @entity101 , together (29.3%, 95%CI 16.5-43.9) representing nearly a five-fold increase over the expected provincial/national average. There were three twin births. The observed rates of Caesarean (43.6%) and preterm (25.6%) delivery, as well as low @entity1 birth weight (22.7%), were also higher than expected, although the rate of @entity154 (4.5%) was not. CONCLUSIONS: The onset of @entity4401 during pregnancy or the puerperium is probably associated with the development of the @entity101 disorders of pregnancy. Pregnant @entity1 who develop @entity4401 should be closely monitored for @entity101 or @entity1468 , and managed accordingly.

Association between XXXX in pregnancy and @entity1468 .

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'patients', 'Women', 'infant'] @entity154 :: ('MESH:D000013', 'Disease') :: ['congenital anomalies'] @entity3152 :: ('MESH:D007752', 'Disease') :: ['preterm delivery'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'hypertensive'] @entity4401 :: ('MESH:D020330', 'Disease') :: ["Bell's palsy"] @entity1468 :: ('MESH:D011225', 'Disease') :: ['pre-eclampsia']
@entity4401 :: (MESH:D020330,Disease) :: ['Bell's palsy']
