CONTEXT: Predicting the severity of acute @entity788 early in the course of the disease is still difficult. OBJECTIVE: The value of amylase and lipase levels in serum and peritoneal fluid might be of value in predicting the course of acute @entity788 . DESIGN: Prospective study. @entity1 : One-hundred and sixty-seven @entity1 with acute @entity788 as confirmed by computed tomography scan within 24 hours of admission were studied. MAIN OUTCOME MEASURES: Each @entity1 was given an enzymatic score which reflected the predominance of serum or peritoneal levels of amylase and/or lipase. Enzymatic score was 0 if neither enzyme was predominant in the peritoneal fluid, 1 if amylase or lipase alone were predominant and 2 if both enzymes were predominant. The predictive value of the enzymatic score or computed tomography scan for a severe attack was determined. RESULTS: One-hundred and thirty-three attacks were graded as mild (79.6%) and 34 were considered as severe (20.4%). The frequency of severe acute @entity788 significantly increased as the enzymatic score increased (5.4%, 12.5%, and 31.7% in 0, 1, and 2 enzymatic score @entity1 , respectively; P<0.001). An enzymatic score greater than 0 predicted a severe outcome in 32 of 34 @entity1 (sensitivity 94.1%, specificity 26.3%), whereas an enzymatic score of 2 predicted a severe attack in 26 of 34 @entity1 (sensitivity 76.5%, specificity 57.9%). @entity4 on computed tomography scan was found in 97 of 129 mild attacks (specificity 75.2%) and @entity39 in 25 of 33 severe attacks (sensitivity 75.8%), whereas all @entity1 with severe attacks exhibited extrapancreatic acute fluid collection (sensitivity 100%, specificity 34.9%). CONCLUSIONS: Peritoneal dialysis is less predictive and more cumbersome than a computed tomography scan in the early prediction of acute @entity788 .

Early prediction in acute XXXX : the contribution of amylase and lipase levels in peritoneal fluid.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity4 :: ('MESH:D004487', 'Disease') :: ['Edema'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatitis'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis']
@entity788 :: (MESH:D010190,Disease) :: ['pancreatitis']
