The incorporation of polymerisable cationic monomers has been attempted to generate dental resinous materials with antibacterial activity. This study tested whether the incorporation of a cationic monomer, @entity70155 ( @entity70155 ), into a commercial dental adhesive would influence the bonding property and biocompatibility of the parental adhesive, and whether @entity70155 could leach out from the cured modified adhesive. Microtensile bond strengths of @entity70155 -incorporated adhesive and its parental adhesive to dentin were compared. Dentin discs bonded with modified adhesive were incubated in artificial saliva at three different temperatures for 90 days to obtain eluents. The @entity137 of @entity70155 monomer and adhesive eluents were tested with @entity2454 cleavage assay ( @entity98 assay). High-performance liquid chromatography (HPLC) was performed with the eluents of the modified adhesive. The results indicated that the incorporation of @entity70155 into the dental adhesive did not adversely influence its bonding strength to dentin (P > 0  05). Although @entity70155 monomer exhibited toxicity against L929 cells at the concentration of 2  g mL(-1) or higher (P < 0  05), the eluents of @entity70155 -incorporated adhesive did not show significant influence on cell growth (P > 0  05). Moreover, HPLC analysis detected four substances' peak baseline separation for the eluents of modified adhesives, which was identical to the eluent of the parental adhesive, indicating no detectable @entity70155 monomer leaching even after soaking for 90 days. Those results suggest that @entity70155 could be incorporated into the dental adhesive stably without compromising the bonding efficiency and biocompatibility of its parental adhesive.

The bonding property and XXXX of a dental adhesive incorporating a new antibacterial monomer.

@entity2454 :: ('MESH:C022616', 'Chemical') :: ['3-(4, 5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide'] @entity98 :: ('CHEBI:53233', 'Chemical') :: ['MTT'] @entity137 :: ('MESH:D064420', 'Disease') :: ['cytotoxicity'] @entity70155 :: ('MESH:C540902', 'Chemical') :: ['methacryloxylethyl cetyl dimethyl ammonium chloride', 'DMAE-CB']
@entity137 :: (MESH:D064420,Disease) :: ['cytotoxicity']
