A 35-year-old @entity1 and a 36-year-old @entity1 presented with abdominal complaints which, in both cases, appeared to be due to an @entity5 , namely a @entity1823 . Three years after radical excision the @entity1 had no complaints, while the male @entity1 had developed @entity3 ; he was still alive 6 years after excision. @entity1823 are @entity5 . Although well defined, these @entity5 are not well known, mainly due to the numerous different names used to describe them in the literature. These @entity5 arise from hyperplastic paraganglionic cells and occur in or near the ganglia of the autonomic nervous system. @entity1823 may produce @entity2661 and, on the basis of this, are classed as either functional or non-functional. In the absence of metastases, there are no definitive clinical, histopathological or molecular-biological parameters to predict whether a @entity5 is benign or malignant. Macroscopic radical surgical excision is therefore the treatment of choice. Five- and ten-year survival rates of a radically excised @entity1823 are 75% and 45%, respectively. In the case of @entity3 , half the @entity1 will die within 3 years. If a @entity1823 is found, genetic screening for @entity5 is advised.

[Two @entity1 with XXXX ].

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'patients', 'patient', 'man'] @entity5 :: ('MESH:D009369', 'Disease') :: ['unusual retroperitoneal tumour', 'familial neoplastic syndromes', 'sporadic tumours', 'tumours', 'neuro-endocrine tumours', 'tumour'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic disease'] @entity1823 :: ('MESH:D010235', 'Disease') :: ['Paragangliomas', 'paraganglioma'] @entity2661 :: ('MESH:D002395', 'Chemical') :: ['catecholamines']
@entity1823 :: (MESH:D010235,Disease) :: ['retroperitoneal paragangliomas']
