PURPOSE: To determine the long-term outcome and prognostic factors after early @entity177 (< 30 days). METHODS: Retrospective analysis of limb salvage data, patency data, and prognostic risk factors in 112 new infrainguinal bypass grafts from 1985 to 1995 that occluded within 30 days of operation. RESULT: Thirty-six femoropopliteal and 76 femorotibial/femoropedal arterial bypass ("index") procedures were performed for @entity158 (50%), tissue loss (31%), or disabling @entity613 (19%). In 103 @entity1 , an immediate additional revascularization ("takeback") procedure was performed at the time of early graft failure. Life table analysis of the takeback procedures for threatened limbs (n = 84) revealed limb salvage rates of 74%, 54%, 40%, and 31% at 1 month, 1 year, 3 years, and 5 years, respectively. The 1-month limb salvage rate (threatened limbs) was 12% (1 of 8) in @entity1 who were not taken back for revascularization and 33% (4 of 12) in @entity1 who had undergone more than one takeback procedure within 30 days. The secondary graft patency rates for the takeback procedures (n = 103) were 70%, 37%, 27%, and 23% at 1 month, 1 year, 3 years, and 5 years, respectively. Univariate and life table analysis revealed that @entity1 who were given anticoagulation medication after the index procedure (before graft @entity715 ) or @entity1 who had undergone previous ipsilateral leg revascularization had significantly lower rates of limb salvage and graft patency (p < 0.05). The limb salvage rate was also significantly worse in @entity1 who had single-vessel runoff compared with those who had multiple-vessel runoff (p < 0.01). Thrombectomy and revision or complete graft replacement had a better secondary patency rate than thrombectomy alone (p < 0.05). Autogenous vein grafts had better outcome than @entity736 -containing grafts, but statistical significance was not achieved. No significant differences in limb salvage or graft patency rates were found between femoropopliteal versus femorotibial/femoropedal bypass grafting, age, gender, previous inflow surgery, @entity6 , @entity101 , smoking, or cardiac, renal, or @entity358 . CONCLUSION: The long-term limb salvage and graft patency rates after takeback revascularization procedures for early graft failure are poor. Despite poor outcome, a single takeback procedure appears warranted in all @entity1 . Multiple takeback procedures, however, do not appear to be justified, especially in @entity1 who are given anticoagulation medication after the index bypass procedure, repeat leg bypass procedures, or if there is no potential for graft revision.

Long-term outcome after early XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity736 :: ('CHEBI:53251', 'Chemical') :: ['polytetrafluoroethylene'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity177 :: ('MESH:D051437', 'Disease') :: ['infrainguinal graft failure'] @entity613 :: ('MESH:D007383', 'Disease') :: ['claudication'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary disease'] @entity158 :: ('MESH:D010146', 'Disease') :: ['rest pain'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity177 :: (MESH:D051437,Disease) :: ['infrainguinal graft failure']
