BACKGROUND: Little is known about the association between race/ethnicity and survival in pediatric @entity978 ( @entity978 ) @entity1 . In a state-wide pediatric cohort diagnosed with @entity978 , we assessed @entity66 , and treatment characteristics associated with @entity1349 ( @entity1349 ). We then attempted to validate these findings and assess @entity66 ( @entity66 ) in a national Surveillance, Epidemiology, and End Results (SEER) cohort. PROCEDURE: @entity978 @entity1 of 0.1-21 years diagnosed from 1981 to 2010 were evaluated using the Florida Cancer Data System (FCDS). Kaplan-Meier curves estimated @entity1349 from 5 to 25 years based on race/ethnicity, treatment, decade of diagnosis, and sex. Multivariate Cox proportional hazard regressions tested independent factors associated with differences in @entity1349 . These methods were replicated in the SEER with additional assessment of @entity66 . RESULTS: A total of 1,778 @entity1 were identified in the FCDS and 6,027 in the SEER. Median diagnosis age was 17 years in both cohorts. In the FCDS, Blacks had worse @entity1349 than Whites and Hispanics at 25 years (33% vs. 49.2% vs. 44.7%, respectively; P = 0.0005), and Black race was associated with inferior @entity1349 on multivariate regression (hazard ratio [HR]: 1.81, P = 0.0003). In the SEER, Blacks had inferior @entity1349 (Blacks 74.2% vs. Whites 82% vs. Hispanics 82%; P = 0.0005) and @entity66 (85.7% vs. 90.8% vs. 88.1%, respectively; P = 0.0002) at 25 years. Hispanic males had inferior @entity66 compared to White males (84.8% vs. 90.6%; P = 0.0478), and Hispanic race was a predictor for inferior @entity66 on multivariate analysis (HR: 1.238; P < 0.0001). CONCLUSIONS: Racial/ethnic disparities persist in the pediatric @entity978 population despite modern treatment; underlying causes of these disparities are complex and need further examination.

Racial and Ethnic Disparities in the Pediatric XXXX Population.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity978 :: ('MESH:D006689', 'Disease') :: ['HL', 'Hodgkin lymphoma'] @entity66 :: ('MESH:D004194', 'Disease') :: ['demographic, disease', 'DSS', 'disease-specific survival'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity978 :: (MESH:D006689,Disease) :: ['Hodgkin Lymphoma']
