PURPOSE: To evaluate the uveal and capsular biocompatibility of hydrophilic acrylic, hydrophobic acrylic, and @entity1346 intraocular lenses (IOLs) in eyes with @entity1596 . SETTING: Department of Ophthalmology, University of Vienna, Vienna, Austria. METHODS: This prospective study comprised 72 eyes with @entity1596 and 68 control eyes having phacoemulsification and IOL implantation by 1 surgeon. @entity1 received 1 of the following IOLs: foldable hydrophilic acrylic (Hydroview, Bausch _ Lomb), hydrophobic acrylic (AcrySof, Alcon), or @entity1346 (CeeOn 911, Pharmacia). Postoperative evaluations were at 1, 3, and 7 days and 1, 3, and 6 months. Cell reaction was evaluated by specular microscopy of the anterior IOL surface and the anterior and posterior capsule reaction, by biomicroscopy. RESULTS: Small round cell deposition was observed on all IOLs in the immediate postoperative period, especially in eyes with @entity1596 . This reaction decreased 3 to 6 months after surgery. Although the CeeOn 911 had a higher mean grade of small cells, there was no statistical difference between the 3 IOL types after 6 months in the @entity1596 and control groups. Foreign-body giant cells (FBGCs) increased after 1 week to 1 month. The AcrySof IOLs had the highest number of FBGCs; after 6 months, there was a statistically significant difference between the AcrySof and @entity1596 groups (P =.036) and the AcrySof and CeeOn 911 @entity1596 groups (P =.003) but there was no difference among the 3 IOL types in the control group. Lens epithelial cell outgrowth persisted on the Hydroview IOLs in control eyes and regressed on all 3 IOL types in @entity735 and on the AcrySof and CeeOn 911 IOLs in control eyes (P =.0001). @entity3236 ( @entity3236 ) was more severe on all IOL types in @entity735 and on the CeeOn 911 IOL in control eyes. @entity3236 ( @entity3236 ) was more severe in @entity735 . The Hydroview group had more severe @entity3236 than the AcrySof and the CeeOn 911 groups in @entity1596 and control eyes. Six months postoperatively, the difference was significant (P =.0001). There was no significant difference between the AcrySof and CeeOn 911 IOLs. CONCLUSIONS: Intraocular lens biocompatibility is inversely related to @entity32 . Hydrophilic acrylic material had good uveal but worse capsular biocompatibility. Hydrophobic acrylic material had lower uveal but better capsular biocompatibility. @entity1346 showed a higher small cell count (mild) and more severe @entity3236 but achieved @entity3236 results comparable to FBGC results and better than those with the AcrySof lens 6 months after surgery. Despite the differences in IOL biocompatibility, all @entity1 benefited from the surgery.

Results of hydrophilic acrylic, hydrophobic acrylic, and @entity1346 intraocular lenses in XXXX with cataract: comparison to a control group.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity1596 :: ('MESH:D014605', 'Disease') :: ['uveitis', 'Hydroview uveitis'] @entity735 :: ('MESH:D005124', 'Disease') :: ['uveitic eyes'] @entity1346 :: ('MESH:D012828', 'Chemical') :: ['Silicone', 'silicone'] @entity3236 :: ('MESH:D058442', 'Disease') :: ['Anterior capsule opacification', 'Posterior capsule opacification', 'PCO', 'ACO']
@entity735 :: (MESH:D005124,Disease) :: ['uveitic eyes']
