Evaluations were performed in 20 @entity1 with childhood @entity3039 ( @entity3039 ) who remained in remission longer than 12 months. The mean duration of follow-up from diagnosis was 39 months (range 17 to 87 months). Eleven @entity1 (four @entity1 ) in group 1 had an acute course of @entity3039 , defined as platelet count greater than 150 X 10(9)/L within 6 months of diagnosis. Nine @entity1 (five @entity1 ) in group 2 had a chronic course, defined as platelet count less than 150 X 10(9)/L for greater than or equal to 1 year or requiring splenectomy in an attempt to control hemorrhagic symptoms. Mean age at diagnosis and duration of follow-up were similar for both groups. Platelet count and serum (indirect) platelet-associated IgG (PAIgG) levels were normal in all 20 @entity1 at follow-up. Both direct and indirect PAIgG levels were measured using a 125I-monoclonal anti-IgG antiglobulin assay. All had normal direct PAIgG levels, except for one @entity1 in group 1 who had a borderline elevated value of 1209 molecules per platelet. These data suggest that the prevalence of elevated platelet antibodies is low during sustained remission without medication in @entity1 with a history of childhood @entity3039 . These data may be relevant for pregnant @entity1 with a history of childhood @entity3039 , with regard to the risk of delivering an @entity1 with @entity882 secondary to transplacental passage of maternal platelet antibody.

Platelet antibody in prolonged remission of childhood XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'girls', 'infant'] @entity3039 :: ('MESH:D016553', 'Disease') :: ['ITP', 'idiopathic thrombocytopenic purpura'] @entity882 :: ('MESH:D013921', 'Disease') :: ['thrombocytopenia']
@entity3039 :: (MESH:D016553,Disease) :: ['idiopathic thrombocytopenic purpura']
