BACKGROUND AND PURPOSE: Protected stenting has emerged as a safe and effective alternative to endarterectomy for the treatment of @entity543 in @entity1 at high operative risk. Distal microembolization occurs invariably during carotid stenting. Little is known about the relationship between systemic @entity32 and embolization during carotid stenting. METHODS: We examined 43 consecutive @entity1 who underwent carotid stenting with simultaneous transcranial Doppler (TCD) monitoring of the ipsilateral middle cerebral artery. Embolization was quantified by measuring @entity7303 ( @entity7303 ) on TCD. Preprocedure leukocyte counts were related to @entity7303 . RESULTS: In unadjusted analyses, preprocedure leukocyte count was positively correlated with total procedural @entity7303 (r2= 0.16; P=0.008). After considering age, gender, comorbidities, concomitant medical therapies, and the use of emboli prevention devices, increasing leukocyte count (beta=35 for each 1000/microL increment; P=0.018) remained a significant and independent predictor of embolization (model-adjusted r2=0.365; P=0.0005). CONCLUSIONS: Increasing preprocedure leukocyte count independently predicted more frequent @entity7303 during carotid stenting. These data suggest that systemic @entity32 may influence the degree of procedural embolization.

Leukocyte count predicts microembolic Doppler signals during carotid stenting: a link between XXXX and embolization.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity7303 :: ('MESH:C566796', 'Disease') :: ['microembolic signals', 'MES'] @entity543 :: ('MESH:D016893', 'Disease') :: ['carotid stenosis']
@entity32 :: (MESH:D007249,Disease) :: ['inflammation']
