The treatment of @entity2876 by variations of the original Kasai hepatoportoenterostomy has shown early success with good bile flow and the elimination of @entity1087 in 50% to 70% of cases in many series. Long-term follow-up in many of these @entity1 shows continued problems with ascending @entity255 and progressive @entity409 leading to @entity204 . Our recent experience with a modified Sawaguchi hepatoportoenterostomy is encouraging. Twelve @entity1 were operated on before two months of age. All but one became @entity1087 free within 2 to 4 months and had biliary intestinal continuity reestablished within 3 to 6 months. These 11 @entity1 have remained @entity1087 free with normal growth and development 1 to 8 years postoperatively. Two @entity1 had one and two episodes of @entity255 , respectively. All have continued mild elevations of hepatocellular enzymes but no @entity1 has obvious signs of @entity1578 . Serial liver biopsies have shown clearing of bile stasis and continued periportal @entity82 . Size and number of ductules in the excised biliary remnant did not correlate with clinical outcome. One @entity1 remained @entity1087 , and eventually expired. In contrast, two @entity1 operated at 4 and 9 months of age never drained bile and eventually died of bleeding varices and @entity1578 , respectively. The atypical success and relative lack of @entity255 in this series is not readily explained, but may be related to specific technical modifications of the original Sawaguchi procedure.

Recent experience with a modified Sawaguchi procedure for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice', 'jaundiced after hepatoportoenterostomy and reoperation'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver disease'] @entity1578 :: ('MESH:D017093', 'Disease') :: ['hepatic failure', 'liver failure'] @entity2876 :: ('MESH:D001656', 'Disease') :: ['biliary atresia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity255 :: ('MESH:D002761', 'Disease') :: ['cholangitis']
@entity2876 :: (MESH:D001656,Disease) :: ['biliary atresia']
