The @entity1187 ( @entity1187 ) have in common @entity397 of a vulnerable plaque, leading to exposure of the subendothelial surface and plaque core. The resultant @entity715 leads to a variable degree of @entity432 , the extent of which differentiates the three syndromes and their treatment by percutaneous coronary intervention (PCI). The guiding principle in the decision when to use PCI in the @entity1187 is that the more time critical and high risk the clinical situation, the more likely it is that PCI will improve ultimate outcome. The use of risk stratification by clinical variables can lead to better triage of @entity1 with non-ST-elevation @entity583 ( @entity583 ) and @entity1459 between PCI and medical management. @entity1 presenting with symptoms suggestive of prolonged @entity63 should have an electrocardiogram searching for ST changes, a targeted physical, and blood drawn for rapid assay of cardiac enzymes. In the event that ST elevations suggest @entity1188 , while medical therapy is initiated, emergency cardiac catheterization can be organized. PCI in @entity1187 requires adjunctive antiplatelet and @entity5582 therapy, and, in general, coronary stenting is advisable. Among @entity1 with non-ST-elevation @entity583 or @entity1459 who can be medically stabilized, the presence of high clinical risk scores would favor early coronary angiography. In their absence, medical therapy can be pursued, unless recurrent @entity63 occurs. When the @entity1 's condition is stable, evaluation by stress testing can be used to guide further decisions.

Interventional therapy of the XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndromes'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia'] @entity1459 :: ('MESH:D000789', 'Disease') :: ['unstable angina'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarction'] @entity432 :: ('MESH:D001157', 'Disease') :: ['flow occlusion'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity5582 :: ('462', 'Gene') :: ['antithrombin']
@entity1187 :: (MESH:D054058,Disease) :: ['acute coronary syndromes']
