PURPOSE: To examine clinical findings and histologic changes on the conjunctival surface in @entity6509 . METHODS: Thirty-five @entity1 with @entity6509 and 30 normal subjects underwent dermatologic and ocular examinations. Tear film break-up time, Schirmer tests with and without topical anesthesia, and conjunctival impression cytology were done. @entity1 were divided into the following groups according to quantity of ocular signs: mild (Group 1), moderate (Group 2), and severe (Group 3). Impression cytology was performed on both upper-bulbar and intrapalpebral inferonasal-bulbar conjunctiva. RESULTS: @entity1 had significant cell alteration on the conjunctival surface compared with normal eyes. The most frequent ocular signs and symptoms were feelings of dryness and @entity14985 . Average tear break-up times for @entity1 with @entity6509 were 8.2 seconds in Group 1, 5.69 seconds in Group 2, and 5 seconds in Group 3 (17.2 seconds in normal subjects). Schirmer test results with anesthesia were 11.5 mm, 7.6 mm, and 5.0 mm, and without anesthesia were 14.8 mm, 13.6 mm, and 7.0 mm, in Groups 1, 2, and 3, respectively. These results were 18.7 mm with anesthesia and 24.7 mm without anesthesia in normal controls. Schirmer tests and tear film break-up time were significantly lower in @entity1 with @entity6509 than in normal controls (p < 0.05). Impression cytology showed that both upper bulbar and inferonasal interpalpebral bulbar ocular surface had significant cell alterations compared with those obtained from normal subjects. CONCLUSIONS: @entity1 with @entity6509 not only had decreased tear production but also tear instability. Ocular surface epithelium had significant degeneration in @entity1 compared with normal subjects.

Impression cytology and ocular characteristics in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity14985 :: ('MESH:D001762', 'Disease') :: ['blepharitis'] @entity6509 :: ('MESH:D012393', 'Disease') :: ['ocular rosacea']
@entity6509 :: (MESH:D012393,Disease) :: ['ocular rosacea']
