Purpose. To evaluate the effectiveness and safety of the @entity22573 as an aid for trabeculectomy performed for primary @entity1538 compared with @entity1138 . Methods. In this prospective, randomized, parallel assignment, comparative study, 31 eyes of 21 primary @entity1538 @entity1 were allocated for trabeculectomy with the Ologen implant; another 32 eyes of 23 @entity1 were treated with trabeculectomy augmented with @entity1138 . The @entity1 were followed up for 5 years and evaluated for intraocular pressure, rate of success, status of the @entity4530 , and adverse events. Result. The mean postoperative intraocular pressure was statistically different at 3   m, 6   m, 1   y, 3   y, and 5   y follow-up. The rates of both complete success (P = 0.017) and overall success (P = 0.031) in the Ologen group were significantly higher than those in the @entity1138 group. The difference of the @entity4530 extent and vascularity was statistically significant in both groups. There was no significant difference in @entity260 . Conclusions. Ologen provides higher rates of surgical success compared with @entity1138 for @entity1 with primary @entity1538 undergoing trabeculectomy. It may be a new, safe, simple, and effective therapeutic approach for treating primary @entity1538 .

Biodegradable 3D-Porous Collagen Matrix (Ologen) Compared with @entity1138 for Treatment of Primary XXXX : Results at 5 Years.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1538 :: ('MESH:D005902', 'Disease') :: ['open-angle glaucoma'] @entity4530 :: ('MESH:D001768', 'Disease') :: ['bleb'] @entity1138 :: ('MESH:D016685', 'Chemical') :: ['mitomycin C'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complication'] @entity22573 :: ('MESH:C058506', 'Chemical') :: ['Ologen']
@entity1538 :: (MESH:D005902,Disease) :: ['Open-Angle Glaucoma']
