BACKGROUND: @entity1047 and @entity2954 screening for @entity1 is beneficial if it prevents serious reproductive sequelae, such as @entity4134 ( @entity4134 ) and @entity5849 ( @entity5849 ). We assessed trends in @entity4134 and @entity5849 among @entity1 in Washington and their association with @entity2954 incidence and @entity1047 positivity in a screened population of @entity1 over a 23 year period. METHODS: Using data on @entity1047 positivity from the Infertility Prevention Project, @entity2954 incidence from state surveillance, and @entity4134 and @entity5849 hospitalizations from hospital discharge records, we assessed trends in each condition over time. In addition, we estimated total incidence of @entity4134 and @entity5849 by incorporating information on outpatient-treated cases in alternative populations using a Bayesian approach that accounted for uncertainty in the estimates. We assessed associations between each infection and @entity4134 / @entity5849 using a linear regression model that accounts for year-to-year correlation in data points. RESULTS: We observed substantial declines in both @entity281 and in each outcome over time. For every 2% decrease in @entity1047 positivity, there was a 35.7/100,000 decrease in estimated total @entity4134 incidence (P = 0.058) and 184.4/100,000 decrease in estimated total @entity5849 (P = 0.149). For every 32/100,000 decline in @entity2954 incidence, there was a 16.5/100,000 decrease in total @entity4134 (P = 0.292) and 159.8/100,000 decrease in total @entity5849 (P = 0.020). The associations with inpatient @entity4134 and @entity5849 were highly significant for both @entity1047 and @entity2954 . CONCLUSIONS: These ecological data note concurrent and substantial declines in @entity1047 positivity and @entity2954 incidence, and in @entity4134 and @entity5849 incidence in Washington from 1988 to 2010 during a time when widespread @entity1047 screening was ongoing.

Assessing Trends in @entity1047 Positivity and XXXX Incidence and Their Associations With the Incidence of @entity4134 and Ectopic Pregnancy in Washington State, 1988-2010.

@entity1 :: ('9606', 'Species') :: ['women'] @entity2954 :: ('MESH:D006069', 'Disease') :: ['gonorrhea'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity5849 :: ('MESH:D011271', 'Disease') :: ['EP', 'ectopic pregnancy'] @entity4134 :: ('MESH:D000292', 'Disease') :: ['PID', 'pelvic inflammatory disease'] @entity1047 :: ('MESH:D002690', 'Disease') :: ['Chlamydia', 'chlamydia']
@entity2954 :: (MESH:D006069,Disease) :: ['Gonorrhea']
