PURPOSE: Treatment of @entity3052 ( @entity3052 ) is associated with substantial adverse effects, including @entity1398 and @entity281 . Viridans streptococci (VS) are a primary cause of @entity281 in @entity1 with @entity1398 . The authors determined the incidence, clinical features, and complications of @entity295 in @entity1 receiving chemotherapy for @entity3052 . METHODS: The authors retrospectively reviewed the records of 172 @entity1 treated on their institutional protocols AML91 (n = 95) and AML97 (n = 77) and identified 36 @entity1 who had @entity295 . RESULTS: The 1-year cumulative incidence of @entity295 was significantly higher in AML97 than in AML91. @entity1 with favorable cytogenetic features (ie, t(9;11), t(8;21), or inv(16)) had a significantly higher incidence of @entity281 than did other @entity1 . @entity295 developed at various times after chemotherapy was initiated, and @entity1 remained febrile for a median of 15 days. Twelve @entity1 (33%) experienced @entity551 , 10 (28%) acute @entity649 , and 6 (17%) @entity364 . Twenty-three @entity1 (64%) required intensive care, 21 (58%), @entity26 therapy, and 7 (19%), vasopressor medications. One @entity1 died of @entity57 after @entity295 . The 3-year cumulative incidence of @entity2381 was higher in @entity1 with @entity295 than in those without. CONCLUSIONS: Although antibiotic therapy rapidly resolved @entity295 , complications associated with this @entity281 remained life-threatening in @entity1 receiving chemotherapy for @entity3052 .

Viridans streptococcal sepsis: clinical features and complications in XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'patient'] @entity295 :: ('MESH:D018805', 'Disease') :: ['VS sepsis'] @entity57 :: ('MESH:D055732', 'Disease') :: ['pulmonary aspergillosis'] @entity649 :: ('MESH:D012128', 'Disease') :: ['respiratory distress syndrome'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['acute myeloid leukemia', 'AML'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection and pneumonia', 'infection'] @entity1398 :: ('MESH:D009503', 'Disease') :: ['neutropenia'] @entity364 :: ('MESH:D009181', 'Disease') :: ['fungal infection'] @entity2381 :: ('MESH:D001228', 'Disease') :: ['aspergillosis'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension']
@entity3052 :: (MESH:D015470,Disease) :: ['childhood acute myeloid leukemia']
