Left atrial (LA) volumes are known to be increased in @entity1121 ( @entity1121 ) and are a predictor of adverse outcome. In addition, LA function is impaired and is presumed to be due to left ventricular (LV) @entity67 as a result of @entity1184 and @entity296 . In the current study, we assess the incremental effect of outflow tract obstruction (and concomitant @entity339 ) on LA function as assessed by LA strain. @entity1 with @entity1121 (50 obstructive, 50 nonobstructive) were compared to 50 normal controls. A subset of obstructive @entity1 who had undergone septal myectomy was also studied. Utilising feature-tracking software applied to cardiovascular magnetic resonance images, LA volumes and functional parameters were calculated. LA volumes were significantly elevated and LA ejection fraction and strain were significantly reduced in @entity1 with @entity1121 compared with controls and were significantly more affected in @entity1 with obstruction. LA volumes and function were significantly improved after septal myectomy. @entity339 appear to further impair LA mechanics. Septal myectomy results in a significant reduction in LA volumes, paralleled by an improvement in function.

Effect of Left Ventricular Outflow Tract Obstruction on Left Atrial Mechanics in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial fibrosis'] @entity339 :: ('MESH:D008944', 'Disease') :: ['LVOT obstruction and mitral regurgitation', 'mitral regurgitation'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['hypertrophy'] @entity67 :: ('MESH:D018754', 'Disease') :: ['diastolic dysfunction'] @entity1121 :: ('MESH:D002312', 'Disease') :: ['HCM', 'hypertrophic cardiomyopathy']
@entity1121 :: (MESH:D002312,Disease) :: ['Hypertrophic Cardiomyopathy']
