OBJECTIVE: Psychogenic @entity410 (PNESs) resemble @entity302 but originate from psychogenic rather than organic causes. @entity1 with PNESs are often unable or unwilling to reflect on underlying emotions. To gain more insight into the internal states of @entity1 during PNES episodes, this study explored the time course of heart rate variability (HRV) measures, which provide information about autonomic nervous system functioning and arousal. METHODS: Heart rate variability measures were extracted from double-lead electrocardiography data collected during 1-7days of video-electroencephalography monitoring of 20 @entity1 with PNESs, in whom a total number of 118 PNESs was recorded. Heart rate (HR) and HRV measures in time and frequency domains (standard deviation of average beat-to-beat intervals (SDANN), root mean square of successive differences (RMSSD), high-frequency (HF) power, low-frequency (LF) power, and very low-frequency (VLF) power) were averaged over consecutive five-minute intervals. Additionally, quantitative analyses of Poincar   plot parameters ( @entity15757 , SD2, and @entity15757 /SD2 ratio) were performed. RESULTS: In the five-minute interval before PNES, HR significantly (p<0.05) increased (d=2.5), whereas SDANN (d=-0.03) and VLF power (d=-0.05) significantly decreased. During PNES, significant increases in HF power (d=0.0006), @entity15757 (d=0.031), and SD2 (d=0.016) were observed. In the five-minute interval immediately following PNES, SDANN (d=0.046) and VLF power (d=0.073) significantly increased, and HR (d=-5.1) and @entity15757 /SD2 ratio (d=-0.14) decreased, compared to the interval preceding PNES. CONCLUSION: The results suggest that PNES episodes are preceded by increased sympathetic functioning, which is followed by an increase in parasympathetic functioning during and after PNES. Future research needs to identify the exact nature of the increased arousal that precedes PNES.

Autonomic nervous system functioning associated with psychogenic XXXX : Analysis of heart rate variability.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['nonepileptic seizures'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epileptic seizures'] @entity15757 :: ('57306', 'Gene') :: ['SD1']
@entity410 :: (MESH:D012640,Disease) :: ['nonepileptic seizures']
