BACKGROUND: To evaluate the cardioprotective effects of @entity2614 versus @entity1875 anesthesia in @entity1 undergoing cardiac surgery. METHODS: Studies were retrieved through searching several databases. Study quality was evaluated by Jadad scale. Meta-analysis was performed with RevMan5.0 software. Publication bias was tested by funnel plot. RESULTS: As a result, 15 studies were included. Compared with @entity1875 , @entity2614 anesthesia significantly improved postoperative ( @entity353 ( @entity353 ) = 0.62, 95% CI: 0.33 to 0.92; P < 0.0001) and postoperative 12 hour cardiac index ( @entity353 = 0.18, 95% CI: 0.03 to 0.33; P = 0.02), @entity998 ( @entity353 = 1.14, 95% CI: 0.74 to 1.54; P < 0.00001), and reduced postoperative 24 hour cardiac troponin I concentration ( @entity353 = -0.86, 95% CI:-1.49 to -0.22; P = 0.008), postoperative inotropic drug usage (OR (odds ratio) = 0.31, 95% CI: 0.22 to 0.44; P < 0.00001), vasoconstrictor drug usage (OR = 0.30, 95% CI:0.21 to 0.43; P < 0.00001), ICU stay ( @entity353 = -15.53, 95% CI: -24.29 to -6.58; P = 0.0007) and a trial fibrillation incidence (OR = 0.25, 95% CI: 0.07 to 0.85; P = 0.03). However, no significant differences were found in other indexes. Subgroup analysis indicated the similar results. DISCUSSION: The @entity2614 -induced @entity6949 reduction is associated with lower incidence of late adverse @entity299 , accounting for its roles in cardiac protection. Several limitations existed such as the small sample size and the lack use of blind design. CONCLUSIONS: @entity2614 may exhibit a more favorable cardioprotective effect during cardiac surgery than @entity1875 .

Meta-analysis of the cardioprotective effect of @entity2614 versus XXXX during cardiac surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity353 :: ('MESH:D015431', 'Disease') :: ['WMD', 'weighted mean difference'] @entity998 :: ('MESH:D002303', 'Disease') :: ['postoperative cardiac output'] @entity6949 :: ('7137', 'Gene') :: ['cTnI'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity2614 :: ('MESH:C009250', 'Chemical') :: ['sevoflurane', 'Sevoflurane']
@entity1875 :: (MESH:D015742,Chemical) :: ['propofol']
