BACKGROUND/AIMS: The purpose of our study was to compare disease-free survival in @entity1 with synchronous @entity14 who underwent delayed hepatic resection or simultaneous resection. METHODOLOGY: All @entity1 who underwent a curative resection of synchronous @entity14 between 2000 and 2006 in our tertiary care referral centre were retrospectively included in our study. @entity1 who underwent the first stage of a two-stage hepatectomy during the primary resection were included in the delayed resection group. Disease-free survival was studied using a Kaplan-Meier method. Prognostic factors for disease-free and overall survival were determined by multivariate analysis using Cox models. RESULTS: One hundred and five @entity1 underwent 85 delayed resections and 20 simultaneous resections. Three and five-year disease-free survival did not differ significantly between simultaneous (50% and 40%) and delayed (65% and 34%) resection groups (P = 0.47). Preoperative carcinoembryonic antigen (HR = 2.05, 95% CI, 1.07-3.92) and presence of extra-hepatic @entity3 (HR = 2.85, 95% CI, 1.08-7.54) were independent prognostic factors for disease-free survival. Three and five-year overall survival did not differ either (23% and 23%; 24% and 20%, P = 0.13). CONCLUSIONS: Simultaneous resection of synchronous @entity14 and primitive @entity5 does not appear to impair long-term disease-free survival.

Disease-Free Survival after Simultaneous or Delayed Resection of Synchronous XXXX and Primary @entity5 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal liver metastasis']
@entity14 :: (MESH:D015179,Disease) :: ['Colorectal Liver Metastasis']
