@entity173 , which is often due to @entity170 or other conditions affecting bone strength, can lead to permanent disability, @entity55 , @entity1151 , and/or @entity204 . Great effort has been directed toward developing noninvasive methods for evaluating proximal femoral strength ( @entity174 load), with the goal of assessing @entity174 risk. Previously, computed tomographic scan-based, linear finite element (FE) models were used to estimate proximal @entity3330 loads ex vivo in two load configurations, one approximating joint loading during single-limb stance and the other simulating impact from a fall. Measured and computed @entity174 loads were correlated (stance, r=0.867; fall, r=0.949). However, precision for the stance configuration was insufficient to identify subjects with below average @entity174 loads reliably. The present study examined whether, for this configuration, nonlinear FE models could be used to identify these subjects. These models were found to predict @entity174 load within +/-2.0 kN (r=0.962). This level of precision is sufficient to identify 97.5% of femora with @entity174 loads 1.3 standard deviations below the mean as having below average @entity174 loads. Accordingly, 20% of subjects with below average @entity174 loads, i.e. those with the lowest @entity174 loads and likely to be at greatest risk of @entity174 , would be correctly identified with at least 97.5% reliability. This FE modeling method will be a powerful tool for studies of @entity173 .

Improved prediction of proximal XXXX load using nonlinear finite element models.

@entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity170 :: ('MESH:D010024', 'Disease') :: ['osteoporosis'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['pulmonary embolism'] @entity173 :: ('MESH:D006620', 'Disease') :: ['Hip fracture', 'hip fracture'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity3330 :: ('MESH:D005264', 'Disease') :: ['femoral fracture']
@entity3330 :: (MESH:D005264,Disease) :: ['femoral fracture']
