OBJECTIVE: To evaluate the significance of reticulated platelets (RPs) in the diagnosis of @entity882 and the relationship between RPs and the proliferative degree of @entity10706 ( @entity10706 ) in bone marrow. METHODS: With @entity6548 orange as a fluorescent dye, RPs were measured by analyzing the RNA content in platelets with flow cytometry and the percent and absolute counts of RPs were calculated. RESULTS: (1) The percent and absolute counts of the RPs in a normal group were (8.4 +/- 2.5)% and (16.8 +/- 6.8) x 10(9)/L respectively. (2) As compared with the normal group, the @entity1 with @entity3039 ( @entity3039 ) and @entity6118 had a significantly high percent and low absolute counts of RPs (P < 0.01). In @entity1 with @entity2150 , both the percent and absolute counts of RPs were at low levels (P < 0.05 and P < 0.01, respectively). There was no difference of @entity6391 percentage between the @entity1 with @entity3052 or @entity2590 syndromes and normal controls, but the absolute counts of RPs in the former was significantly lower than that in the latter. There was no difference between the percent and absolute counts of RPs among @entity3039 @entity1 with different proliferative degree of @entity10706 in bone marrow. (3) In all the diseases mentioned above, it was shown that @entity6391 percentage returned to normal in the effective cases after treatment, but no such change was found in the ineffective cases. CONCLUSIONS: Reticulated platelet counts contribute to the aetiology determination of the @entity882 . It is also a valuable diagnostic method and a monitoring marker. There is no relationship between reticulated platelet counts and the counts of @entity10706 proliferation in bone marrow.

[The value of reticulated platelet counts in diagnosing XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6548 :: ('CHEBI:43732', 'Chemical') :: ['thiazole'] @entity882 :: ('MESH:D013921', 'Disease') :: ['thrombocytopenic disorders', 'thrombocytopenia'] @entity2150 :: ('MESH:D000741', 'Disease') :: ['aplastic anemia'] @entity2590 :: ('MESH:D009190', 'Disease') :: ['myelodysplastic'] @entity6391 :: ('MESH:D012174', 'Disease') :: ['RP'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['acute leukemia'] @entity10706 :: ('MESH:D007947', 'Disease') :: ['megakaryocyte', 'MK'] @entity6118 :: ('MESH:D006971', 'Disease') :: ['hypersplenism'] @entity3039 :: ('MESH:D016553', 'Disease') :: ['ITP', 'idiopathic thrombocytopenic purpura']
@entity882 :: (MESH:D013921,Disease) :: ['thrombocytopenic disorders']
