UNASSIGNED: With more @entity1 surviving a @entity1313 , insight into the late effects of the disease and treatment is of high importance. This study focused on profiling the neurocognitive functions that might be affected after treatment for a pediatric @entity1313 , using a broad battery of computerized tests. Predictors that may influence neurocognitive functioning were also investigated. A total of 82 pediatric @entity1313 survivors (PBTSs) aged 8-18  years (M  =  13.85, SD  =  3.15, 49% males) with @entity149 were compared to a control group of 43 siblings (age M  =  14.27, SD  =  2.44, 40% males) using linear mixed models. Neurocognitive performance was assessed using measures of attention, processing speed, memory, executive functioning, visuomotor integration (VMI), and intelligence. Tumor type, treatment, @entity5 location, @entity1276 , gender, age at diagnosis, and time since diagnosis were entered into regression analyzes as predictors for neurocognitive functioning. The PBTSs showed slower processing speeds and lower intelligence (range effect sizes .71-.82, p  <  .001), as well as deficits in executive attention, short-term memory, executive functioning, and VMI (range effect sizes .40-.57, p  <  .05). Older age at assessment was associated with better neurocognitive functioning (B  =  .450, p  <  .001) and younger age at diagnosis was associated with lower intelligence (B  =  .328, p  <  .05). Medical risk factors, e.g., @entity1276 , did not show an association with neurocognitive functioning. Late effects in PBTSs include a broad range of @entity149 . The results suggest that even PBTSs that were traditionally viewed as low risk for @entity149 (e.g., surgery only, no @entity1276 ) may suffer from @entity149 .

Timed performance weaknesses on computerized tasks in pediatric XXXX survivors: A comparison with sibling controls.

@entity1 :: ('9606', 'Species') :: ['children'] @entity1276 :: ('MESH:D006849', 'Disease') :: ['hydrocephalus'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['brain tumor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity149 :: ('MESH:D002493', 'Disease') :: ['neurocognitive problems', 'parent-reported neurocognitive complaints', 'neurocognitive deficits', 'decreased neurocognitive functioning']
@entity1313 :: (MESH:D001932,Disease) :: ['brain tumor']
