BACKGROUND: Definitive management with hysterectomy could be appropriate for some @entity1 with @entity1204 and its precursor lesions, but poses challenges for those desiring future fertility. OBJECTIVES: To review risk factors for @entity1869 / @entity5 among premenopausal @entity1 and discuss management options for fertility preservation. SEARCH STRATEGY: A literature search through the PubMed, Ovid, and Cochrane databases was conducted using the terms " @entity1869 " and " @entity1204 ," cross-referenced with "fertility preservation." SELECTION CRITERIA: All articles published in English between January 1, 2000, and January 1, 2015, were considered if they were readily available online. DATA COLLECTION AND ANALYSIS: Articles were analyzed and information was synthesized into a comprehensive review. MAIN RESULTS: @entity3206 , @entity28 , @entity3610 , @entity209 , insulin resistance, and @entity6 must be appreciated as risk factors for endometrial pathology. Providers must exert vigilance in identifying @entity1 at risk and in initiating pre-emptive strategies. Risk reduction with lifestyle modification, weight loss, and glycemic control can improve regression and overall health. Fertility outcomes for these @entity1 are promising, especially with assisted reproductive technology. CONCLUSIONS: Conservative management could be appropriate for carefully selected @entity1 with @entity1869 or early-stage @entity1204 who desire future fertility.

Management options and fertility-preserving therapy for @entity1869 and early-stage XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity1204 :: ('MESH:D016889', 'Disease') :: ['endometrial cancer'] @entity3610 :: ('MESH:D011085', 'Disease') :: ['polycystic ovarian syndrome'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity6 :: ('MESH:D003920', 'Disease') :: ['type 2 diabetes mellitus'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity3206 :: ('MESH:D000858', 'Disease') :: ['Chronic anovulation'] @entity1869 :: ('MESH:D004714', 'Disease') :: ['complex atypical endometrial hyperplasia', 'endometrial hyperplasia'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic syndrome']
@entity1204 :: (MESH:D016889,Disease) :: ['endometrial cancer']
