UNASSIGNED: The goal of this study was to identify associations between positron emission tomography/computed tomography (PET/CT) maximum standardized uptake value (SUVmax) in @entity1 presenting with @entity213 (SCC) with @entity5 site, size, histologic differentiation, smoking, and @entity6 . Charts of @entity1 with oropharyngeal and laryngeal SCC who underwent @entity419 PET/CT scans were reviewed between May 2007 and August 2013. Statistical analyses included modeling log-transformed SUVmax values by @entity5 site, size, histologic differentiation, smoking status, and @entity6 using unadjusted linear regressions. Differences were considered statistically significant for P< 0.05. A total of 111 @entity1 (54 with oropharynx and 57 with @entity5 ) were included, 83 @entity1 and 28 @entity1 with an average age of 57.5 years old. There was a significantly higher pack-year smoking history (P = 0.005) in the @entity5 group. While @entity5 T-stage was found to be significantly different (P < 0.0001), there was no difference in @entity5 size between the two groups: 3.16 cm and 3.58 cm in the oropharynx and larynx, respectively (P = 0.55). In the oropharynx cohort, SUVmax was associated with both @entity5 size (P = 0.0001) and stage (P < 0.0002). Interestingly, SUVmax differed by @entity5 differentiation in the larynx (P = 0.04) but not the oropharynx (P = 0.71). Finally, there was no significant difference in SUVmax relative to @entity6 and smoking status. PET/CT SUVmax correlated with both @entity5 size and stage in @entity5 @entity1 , and it correlated only with @entity5 differentiation but not the size or stage in the larynx. There were no significant differences in SUVmax by @entity6 or smoking status.

Correlation of Positron Emission Tomography/Computed Tomography Scan with Smoking, Tumor Size, Stage and Differentiation in Head and Neck Cancer XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity419 :: ('MESH:D019788', 'Chemical') :: ['(18)F-fluorodeoxyglucose'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity5 :: ('MESH:D009369', 'Disease') :: ['larynx cancers', 'tumor', 'oropharyngeal cancer', 'larynx cancer'] @entity213 :: ('MESH:C535575', 'Disease') :: ['head and neck squamous cell carcinoma']
@entity1 :: (9606,Species) :: ['Patients']
