BACKGROUND: Recovery of myocardial function after revascularization of acutely occluded coronary arteries may require several days. During this critical time, @entity1 in @entity1455 may have low output. A newly developed percutaneous left @entity67 ( @entity67 ) may offer effective treatment for these @entity1 by providing active circulatory support. METHODS AND RESULTS: Between May 2000 and May 2001, VADs were implanted in 18 consecutive @entity1 who had @entity1455 after @entity583 . The device was connected to the @entity1 's circulation by insertion of a 21F venous cannula into the left atrium by transseptal puncture; blood was returned to the iliac artery through an arterial cannula. Mean duration of cardiac assistance was 4+/-3 days. Mean flow of the @entity67 was 3.2+/-0.6 L/min. Before support, cardiac index was 1.7+/-0.3 L/min per m(2) and improved to 2.4+/-0.6 L/min per m(2) (P<0.001). Mean blood pressure increased from 63+/-8 mm Hg to 80+/-9 mm Hg (P<0.001). Pulmonary capillary wedge pressure, central venous pressure, and pulmonary artery pressure were reduced from 21+/-4, 13+/-4, and 31+/-8 mm Hg to 14+/-4, 9+/-3, and 23+/-6 mm Hg (all P<0.001), respectively. Overall 30-day mortality rate was 44%. CONCLUSIONS: A newly developed @entity67 can be rapidly deployed in the catheterization laboratory setting. This device provides up to 4.0 L/min of assisted cardiac output, which may aid to revert @entity1455 . The left ventricle is unloaded by diverting blood from the left atrium to the systemic circulation, making recovery more likely after an ischemic event. The influence of this device on long-term prognosis warrants further investigation.

Reversal of XXXX by percutaneous left atrial-to-femoral arterial bypass assistance.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity67 :: ('MESH:D018754', 'Disease') :: ['ventricular assist device', 'VAD'] @entity1455 :: ('MESH:D012770', 'Disease') :: ['cardiogenic shock']
@entity1455 :: (MESH:D012770,Disease) :: ['cardiogenic shock']
