A 75-year-old @entity1 presented with severe @entity490 and @entity294 . Symptoms started 10   years earlier but multiple investigations failed to offer a clear diagnosis. On recent admission, blood tests, endoscopies and CT scans indicated chronic @entity32 . Treatment strategies for bowel @entity32 were unsuccessful and the @entity1 was subsequently discussed at a multidisciplinary team meeting with surgeons for consideration of colectomy. A drug review highlighted that the @entity1 was taking an antiangina drug, @entity7976 , thought to cause bowel @entity1066 . This was discontinued, which dramatically improved symptoms and avoided surgery and the @entity1 was discharged within days. Follow-up colonoscopy showed much improved @entity1960 , and the @entity294 had resolved. It is important that clinicians are aware of the link between pharmacotherapy, specifically @entity7976 and gastrointestinal @entity1066 and @entity32 causing severe @entity294 . Drug cessation is the only necessary and immediately effective treatment. Awareness of this will become more clinically relevant as @entity7976 use increases.

When treatment can be worse than the disease: XXXX -induced @entity1960 .

@entity1 :: ('9606', 'Species') :: ['woman', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['colonic inflammation', 'inflammation'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhoea'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulceration'] @entity1960 :: ('MESH:D003092', 'Disease') :: ['colitis'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity7976 :: ('MESH:D020108', 'Chemical') :: ['nicorandil']
@entity7976 :: (MESH:D020108,Chemical) :: ['nicorandil']
