@entity1278 (BN) are @entity1277 characterized by an aberrant pattern of eating behavior, relentless pursuit of thinness, an intense fear about @entity1017 and an altered perception of body shape. The pathobiology of @entity1277 is complex. Several social, psychological and developmental phenomena are proposed to contribute to the etiology of @entity1277 . The role of @entity7766 , corticotropin releasing hormone and leptin has also been investigated to understand the pathogenesis of @entity1277 . However, most of the neuropeptide alterations noted in @entity1277 are secondary to starvation. Several nonpharmacological approaches such as cognitive and behavior-based therapy and interpersonal therapy have been developed to assist @entity1017 and to modify the behavioral impairment associated with @entity1277 . Pharmacotherapy serves as an adjunct in @entity1278 , whereas it plays a more significant role in the management of BN. Antidepressants are effective in a limited number of @entity1278 @entity1 with comorbid @entity308 . On the other hand, the efficacy of @entity905 in BN @entity1 in reducing the frequency of binge eating and in the severity of @entity146 is quite impressive. Several adjunct therapies such as prokinetics and anxiolytics have also been used in @entity1278 and BN to assist eating behavior. An insight into genetic and @entity854 occurring in @entity1277 will help to find better therapeutic agents for these disorders. (c) 2001 Prous Science. All rights reserved.

XXXX : An appraisal.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity905 :: ('MESH:D005473', 'Chemical') :: ['fluoxetine'] @entity146 :: ('MESH:D001523', 'Disease') :: ['behavioral abnormalities'] @entity7766 :: ('4852', 'Gene') :: ['neuropeptide Y'] @entity1278 :: ('MESH:D000856', 'Disease') :: ['Anorexia nervosa (AN) and bulimia nervosa', 'AN'] @entity854 :: ('MESH:D018376', 'Disease') :: ['neurochemical abnormalities'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity1277 :: ('MESH:D001068', 'Disease') :: ['eating disorders']
@entity1278 :: (MESH:D000856,Disease) :: ['Anorexia nervosa and bulimia nervosa']
