The occurrence and distribution of neuropeptide-containing fibres in the @entity1 parotid gland were examined by the peroxidase-antiperoxidase method with attention to the quality of fixation and the condition of @entity1 . Many fibres immunoreactive for @entity7766 ( @entity7766 ) and vasoactive intestinal polypeptide ( @entity3549 ) and a moderate number of @entity2537 were distributed around the acini. A moderate number of @entity7766 and @entity3549 fibres were distributed around the intercalated ducts. The semiquantitative mean densities (+/- SD) of periacinar @entity7766 , @entity3549 and GAL fibres expressed as a percentage of the total protein gene product (PGP) 9.5 immunoreactive fibres were 75.62 +/- 7.25%, 70.52 +/- 9.33% and 41.76 +/- 5.45%, respectively, whereas those of substance @entity10133 ), calcitonin gene-related peptide ( @entity10132 ) and FMRF @entity6346 (FMRF) fibres were below 10%. The mean densities of @entity7766 and @entity3549 fibres around the intercalated ducts expressed as the percentage of @entity5855 fibres associated with these ducts were 52.37 +/- 6.19% and 59.62 +/- 7.02% respectively. Those of SP, @entity10132 , GAL, and FMRF fibres were below 10%. The densities of @entity7766 , @entity3549 , SP, @entity10132 , GAL and FMRF fibres around the striated and excretory ducts were also below 10%. In the vasculature, @entity7766 fibres were the most prominent. Similarly, the mean density of perivascular @entity7766 fibres was 93.76 +/- 2.03%. No somatostatin or @entity368 or @entity1853 enkephalin immunoreactivity was detected around the acini, duct system or blood vessels. These findings suggest that, in this gland, the periacinar @entity7766 , @entity3549 and GAL fibres may participate in regulating the synthesis of saliva and its secretion and that perivascular peptidergic fibres, especially @entity7766 fibres, may be involved in controlling local blood flow.

Neuropeptide-containing nerve fibres in the XXXX parotid gland: a semiquantitative analysis using an antibody against protein gene product 9.5.

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity10133 :: ('2155', 'Species') :: ['P (SP'] @entity3549 :: ('7432', 'Gene') :: ['VIP'] @entity368 :: ('CHEBI:25017', 'Chemical') :: ['leucine'] @entity7766 :: ('4852', 'Gene') :: ['neuropeptide Y', 'NPY'] @entity2537 :: ('MESH:D020966', 'Disease') :: ['galanin-positive (GAL) fibres'] @entity10132 :: ('796', 'Gene') :: ['CGRP'] @entity1853 :: ('MESH:D008715', 'Chemical') :: ['methionine'] @entity5855 :: ('7345', 'Gene') :: ['PGP 9.5'] @entity6346 :: ('CHEBI:32988', 'Chemical') :: ['amide']
@entity1 :: (9606,Species) :: ['human']
