Amphibians in terrestrial environments obtain water through a highly vascularized pelvic patch of skin. Chemicals can also be exchanged across this patch. @entity12472 ( @entity10664 ), a widespread herbicide, continues to be a concern among amphibian ecologists based on potential exposure and @entity137 . Few studies have examined its impact on the terrestrial juvenile or adult stages of toads. In the current study, we asked the following questions: (1) Will juvenile American toads (Bufo americanus) avoid soils contaminated with @entity10664 ? (2) Can they absorb @entity10664 across the pelvic patch? (3) If so, how is it distributed among the organs and eventually eliminated? We conducted a behavioral choice test between control soil and soil dosed with ecologically relevant concentrations of @entity10664 . In addition, we examined the uptake, distribution, and elimination of water dosed with @entity3209 -labeled @entity10664 . Our data demonstrate that toads do not avoid @entity10664 -laden soils. @entity10664 crossed the pelvic patch rapidly and reached an apparent equilibrium within 5 h. The majority of the radiolabeled @entity10664 ended up in the intestines, whereas the greatest concentrations were observed in the @entity1085 . Thus, exposure of adult life stages of amphibians through direct uptake of @entity10664 from soils and runoff water should be considered in risk evaluations.

Behavioral response and kinetics of terrestrial XXXX exposure in American toads (Bufo americanus).

@entity1085 :: ('MESH:D005705', 'Disease') :: ['gall bladder'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity10664 :: ('CHEBI:37924', 'Chemical') :: ['ATZ'] @entity12472 :: ('MESH:D001280', 'Chemical') :: ['Atrazine'] @entity3209 :: ('CHEBI:36927', 'Chemical') :: ['(14)C']
@entity12472 :: (MESH:D001280,Chemical) :: ['atrazine']
