We present the case of a 70-year-old non- @entity6 @entity1 who presented to the emergency department with unrelenting @entity7867 . A severe @entity12088 ( @entity12088 ) and @entity2267 were treated with broad spectrum antibiotics and surgical drainage. No bacteria was isolated from surgical samples. Because the @entity7867 persisted, a magnetic resonance (MR) was performed and showed an infiltrating process at the skull base. Biopsies failed to prove @entity5 or @entity2883 . The @entity1 's neurological state deteriorated. The suspicion of a @entity1297 ( @entity1297 ) was raised and proven by CT-guided biopsies that grew @entity796 . @entity2889 and @entity2177 , given for 8 weeks, lead to a fast clinical improvement and a full recovery. @entity1297 is uncommon, often complicating severe @entity12088 . @entity796 is the main pathogen. Prompt diagnosis and adequate antibiotherapy are required to lower mortality and morbidity. The diagnosis may be delayed because of unawareness and large differential diagnosis including solid @entity5 , @entity5 and @entity2883 .

Central XXXX : a rare but life-threatening disease.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity796 :: ('287', 'Species') :: ['Pseudomonas aeruginosa'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant hemopathies', 'neoplasic tumours', 'malignancy'] @entity2177 :: ('MESH:D002939', 'Chemical') :: ['ciprofloxacin'] @entity1297 :: ('MESH:D019292', 'Disease') :: ['skull base osteomyelitis', 'SBO'] @entity2889 :: ('MESH:C059500', 'Chemical') :: ['Meropenem'] @entity12088 :: ('MESH:D010032', 'Disease') :: ['OE', 'otitis externa'] @entity2267 :: ('MESH:D008417', 'Disease') :: ['mastoiditis'] @entity2883 :: ('MESH:D014890', 'Disease') :: ['granulomatosis'] @entity7867 :: ('MESH:D004433', 'Disease') :: ['otalgia']
@entity1297 :: (MESH:D019292,Disease) :: ['skull base osteomyelitis']
