BACKGROUND AND PURPOSE: The aim of this study was to assess the relationship between cardiovascular risk factors, @entity731 in the carotid bifurcation, and the risk of @entity64 and mortality in a representative population sample. METHODS: One hundred forty-two @entity1 and @entity1 participated in a population study at ages 70 and 76 years. At age 78, extracranial and intracranial circulation was examined by means of duplex sonography and transcranial Doppler techniques. Mortality and hospitalization for @entity64 were analyzed over a 5-year follow-up period up to age 83 years. RESULTS: Carotid plaques were identified in 82% of the @entity1 and 79% of the @entity1 . Bilateral plaques were found in 57% of the @entity1 and 46% of the @entity1 , and @entity850 resulting in >50% diameter reduction occurred in 28% of the @entity1 and 17% of the @entity1 . @entity543 >75% was observed in 7 subjects (0.5%). Bilateral plaques at age 78 were correlated with systolic blood pressure and @entity741 at age 70 years. The pulsatility index was 1.0 to 1.4 in 63% and > or =1.5 in 13% of the study population. The pulsatility index was correlated with systolic and diastolic blood pressure, serum @entity165 , and @entity1674 . @entity1 with bilateral carotid plaques at age 78 years had an increased risk of @entity64 or mortality during the 5-year follow-up period (74% bilateral plaques versus 21% unilateral or no plaques). This was not found in the @entity1 (33% versus 26%). CONCLUSIONS: @entity2998 was prevalent in a majority of elderly subjects. Bilateral plaques were correlated with systolic blood pressure and @entity741 at age 70 years and predicted the risk of @entity64 and mortality in @entity1 but not in @entity1 .

Cerebral atherosclerosis as predictor of XXXX and mortality in representative elderly population.

@entity1 :: ('9606', 'Species') :: ['women', 'Men', 'men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity2998 :: ('MESH:D002340', 'Disease') :: ['Carotid atherosclerosis'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic disease'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity543 :: ('MESH:D016893', 'Disease') :: ['Carotid stenosis'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity64 :: (MESH:D020521,Disease) :: ['stroke']
