OBJECTIVES: Aging is associated with declines in executive function and @entity2414 . @entity410 ( @entity410 ) has been associated with enhanced executive function in @entity4479 ( @entity4479 ), but the relationship with @entity2414 remains unclear. The purpose of the study was to examine the relationship between @entity410 and cognition in young and @entity4479 and whether @entity410 mitigates age-related @entity73 . METHODS: @entity1 completed exercise testing to evaluate @entity410 (peak VO2) and neuropsychological testing to assess cognition. RESULTS: In @entity4479 , peak VO2 was positively related to executive function, as well as to accuracy on an experimental face-name memory task and @entity227 . In young adults (YA), a relationship between peak VO2 and cognition was not evident. High-fit @entity4479 performed as well as YA on executive function measures. On @entity2414 measures, YA performed better than high-fit @entity4479 , who in turn performed better than low-fit @entity4479 . CONCLUSIONS: @entity410 is positively associated with executive function and @entity2414 in @entity4479 and attenuates age-related @entity73 . We provide preliminary support for the age-dependence hypothesis, which posits that cognition and @entity410 relationships may be most readily observed during lifetime periods of significant neurocognitive development.

XXXX Is Associated With Cognitive Performance in Older But Not Younger Adults.

@entity1 :: ('9606', 'Species') :: ['Participants'] @entity410 :: ('MESH:D012640', 'Disease') :: ['Cardiorespiratory fitness', 'CRF'] @entity4479 :: ('MESH:C538052', 'Disease') :: ['OA', 'older adults'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual episodic memory'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive decline'] @entity2414 :: ('MESH:D008569', 'Disease') :: ['episodic memory']
@entity410 :: (MESH:D012640,Disease) :: ['Cardiorespiratory Fitness']
