BACKGROUND:: Central nervous system (CNS) @entity2698 are @entity361 of the brain. In the absence of randomized clinical trials or large studies, the only information we have about the natural history and the management is from isolated clinical case series. They have suggested that surgery is beneficial, with conflicting results on the role of complete resection and adjuvant radiation. We have conducted a systematic review of clinical case series of CNS @entity2698 analyzing the biology of the @entity5 and the best follow-up and management strategy. METHODS:: Fifteen pertinent clinical case series on newly diagnosed CNS @entity2698 were selected by a review of literature. A total of 523 @entity1 were analyzed for age, sex, mode of recurrence and @entity3 , and survival after complete/incomplete resection with or without radiation. RESULTS:: The mean age was found to be 44.17 (  3.59) years. The incidence was higher in male individuals younger than 45 years and in older female individuals. Complete resection and adjuvant radiation significantly improved survival in comparison with incomplete resection and no radiation, respectively (P<0.0001). Furthermore, a significant trend of the @entity5 to recur locally compared with extraneural and neural axis @entity3 was noted (P<0.0001). The mean time for distant @entity3 was seen to be 91.33 (  12.66) months. CONCLUSIONS:: Complete resection followed by adjuvant radiation improves survival. Extraneural @entity3 , especially to lung, bone, and liver, are not uncommon and can occur late in the disease course for which continued follow-up is required. There is also a need to establish a systemic treatment regimen to control the distant @entity3 .

CNS @entity2698 : A Systematic Review of 523 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2698 :: ('MESH:D006393', 'Disease') :: ['hemangiopericytomas', 'hemangiopericytoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity361 :: ('MESH:C535700', 'Disease') :: ['rare mesenchymal tumors']
@entity1 :: (9606,Species) :: ['Patients']
