STUDY DESIGN: Retrospective Cohort Study OBJECTIVES.: The objective of our study was to evaluate the differential impact of @entity2690 dependence on lumbar surgery outcomes, including surgical and medical complications, total length of hospital stay, non-home bound discharge, and unplanned readmissions. SUMMARY OF BACKGROUND DATA: While the negative effects of @entity6 ( @entity6 ) on joint arthroplasty outcomes are well documented, there is a paucity of studies evaluating those on spine surgery. METHODS: Data files from 2005 to 2013 were reviewed and to collect data on @entity1 undergoing lumbar spine surgery. Chi-square tests, for categorical variables, and one-way ANOVA, for continuous variables, were used to identify differences in perioperative variables among @entity1 who do not have @entity6 , who are @entity2690 -independent ( @entity2175 ), who are @entity2690 -dependent ( @entity1723 ). Binary logistic regression analysis assessed the effect of @entity6 status on surgical outcomes. Significance was defined as P<0.05. RESULTS: Significant differences were detected among the three groups in surgical and medical complication and unplanned readmission rates, as well as rates of non-home bound discharge. The @entity2175 and @entity1723 groups experienced significantly longer mean total hospital length of stay at 3.2 and 3.9 days, respectively, compared to 2.6 days for non-diabetics (P<.0001). Both @entity2175 (OR, 1.226; P=.017) and @entity1723 (OR, 1.499; P<.0001) independently increased the risk for medical complications while only @entity1723 (OR, 2.429; P<.0001) was associated with surgical complications. @entity1723 was found to be associated with increased rate of 30-day unplanned readmission (OR, 1.353; P=.005). Neither @entity2175 nor @entity1723 had an effect on the likelihood of non-home discharge. CONCLUSIONS: We hope our findings improve risk stratification efforts and informed consent for two @entity6 @entity1 populations. In addition, our findings advocate for appropriate risk stratification of a subgroup @entity6 @entity1 who are dependent on @entity2690 and are at greater risk for surgical morbidity. LEVEL OF EVIDENCE: 3.

Impact of @entity2690 Dependence on Lumbar Surgery Outcomes: A NSQIP Analysis of 51,277 XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2175 :: ('MESH:D003924', 'Disease') :: ['NIDDM'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes Mellitus', 'DM'] @entity2690 :: ('3630', 'Gene') :: ['insulin'] @entity1723 :: ('MESH:D003922', 'Disease') :: ['IDDM']
@entity1 :: (9606,Species) :: ['Patients']
