@entity2622 frequently metastasizes to the paraaortic region, necessitating extended field radiotherapy to effect a cure. As imaging modalities are unreliable in identifying all cases of paraaortic nodal metastases (PAN), surgical staging is often utilized prior to radiotherapy. This study was aimed at identifying factors predictive of survival in @entity1 with @entity2622 and paraaortic @entity3 . In particular, survival based on extent of @entity66 was examined. The study group consisted of 43 @entity1 (stages IB-IVB) identified between 1982 and 1993 who were treated with extended field radiation for cervical @entity189 with histologically confirmed paraaortic @entity3 . The estimated 5-year survival for the study population was 24% with a median survival of 18 months. @entity530 size had a significant impact on survival with the median survival being 34 months if the @entity75 was < 6 cm compared to 14 months if > or = 6 cm (P = 0.01). Eight of the 26 (31%) @entity1 without residual PAN disease after surgical staging remain alive and disease free (mean follow-up, 74 months). In contrast, only 1 of the 17 (6%) @entity1 with gross residual PAN is alive 71 months after treatment (P = 0.05). However, a comparison of Kaplan-Meier survival curves did not show a statistically significant advantage to the surgical excision of grossly involved PAN (P = 0.98). Although long-term survival among @entity1 with grossly involved, unresected paraaortic @entity3 is uncommon, further study is necessary to elucidate the role of surgical excision of bulky @entity2333 in @entity1 with @entity5 .

XXXX with paraaortic metastases: significance of residual paraaortic disease after surgical staging.

@entity1 :: ('9606', 'Species') :: ['women'] @entity66 :: ('MESH:D004194', 'Disease') :: ['paraaortic disease'] @entity75 :: ('MESH:D001927', 'Disease') :: ['primary lesion'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cervical cancer'] @entity2622 :: ('MESH:D002583', 'Disease') :: ['cervical carcinoma', 'Cervical carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma'] @entity530 :: ('MESH:D010386', 'Disease') :: ['Pelvic tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity2333 :: ('MESH:D001018', 'Disease') :: ['aortic disease']
@entity5 :: (MESH:D009369,Disease) :: ['Cervical cancer']
