PURPOSE: To confirm the validity of postoperative @entity908 kinase (CK) values as an indicator of @entity121 , assess the relationship of CK with variables indicating surgical invasiveness and investigate an association between CK values and excessive @entity282 . MATERIAL AND METHODS: The study included 96 @entity1 (mean age 62.8 years) who underwent instrumented spine fusion for @entity179 . Serum CK concentration was determined on the first postoperative day. All @entity1 received intravenous @entity1443 and @entity10964 , and in cases of intense @entity158 , rescue analgesia with iv @entity6882 . @entity1 were categorized according to whether or not they required rescue analgesia. Data on the number of levels fused, the duration of surgery, and @entity548 were recorded in each @entity1 . RESULTS: CK values were higher in @entity1 and in younger @entity1 . Significant correlations were found between CK and the number of fused levels and duration of surgery. Only 17.7% of @entity1 required rescue analgesia. CK levels did not significantly differ between @entity1 who did not need rescue analgesia (1135 IU/L) and those who did (1421.5 IU/L). CONCLUSIONS: Serum CK concentration is a valid marker of surgical @entity121 and is affected by the age and sex. Factors such as the magnitude and duration of surgery show a relationship with postoperative CK values. The incidence of severe @entity282 is not significantly related to CK level.

Validity of @entity908 kinase as an indicator of @entity121 in spine surgery and its relation with XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'men'] @entity10964 :: ('MESH:D004177', 'Chemical') :: ['metamizole'] @entity548 :: ('MESH:D006470', 'Disease') :: ['operative bleeding'] @entity908 :: ('MESH:D003401', 'Chemical') :: ['creatine'] @entity6882 :: ('MESH:D008614', 'Chemical') :: ['meperidine'] @entity179 :: ('MESH:D019636', 'Disease') :: ['degenerative lumbosacral disease'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['paracetamol'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity121 :: ('MESH:D009135', 'Disease') :: ['muscle injury', 'muscle lesion']
@entity282 :: (MESH:D010149,Disease) :: ['postoperative pain']
