@entity651 during @entity295 after @entity130 to be amplified with plasma fibronectin deficiency, but the degree of injury relative to the extent of @entity295 has not been defined. We evaluated pulmonary vascular permeability in @entity742 as influenced by various levels of @entity86 during a period of plasma fibronectin deficiency. The hemodynamic response to Pseudomonas was very similar regardless of the intensity of septic challenge and characterized by systemic arterial @entity551 , @entity998 , and @entity120 . In contrast, increased pulmonary microvascular permeability was observed with increments in the bacterial challenge. Thus, lung protein clearance (LPC) or so called pulmonary @entity1131 ( @entity1131 ) used as an index of lung vascular permeability was 9.1 +/- 1.9 ml/hr, 15.1 +/- 1.7 ml/hr, and 19.3 +/- 3.0 ml/hr 2 hr after low (3 X 10(9) i.v.; 1 X 10(10) i.p.), medium (3 X 10(9) i.v.; 3 X 10(10) i.p.), and high (5 X 10(9) i.v.; 5 X 10(10) i.p.) dose Pseudomonas challenges, respectively. Thus, the extent of the altered pulmonary microvascular integrity in @entity742 during @entity295 after surgery in the presence of fibronectin deficiency is dependent on the degree of @entity2348 . In addition, infusion of cryoprecipitate was an effective means of reversing the plasma fibronectin deficiency. Accordingly, this may be used as a model to investigate the mechanism of altered lung fluid balance during @entity86 and the effect of fibronectin on this response.

Lung fluid and protein flux during XXXX .

@entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity742 :: ('9940', 'Species') :: ['sheep'] @entity998 :: ('MESH:D002303', 'Disease') :: ['decreased cardiac output'] @entity1131 :: ('MESH:D011488', 'Disease') :: ['TPC', 'transvascular protein clearance'] @entity120 :: ('MESH:D006976', 'Disease') :: ['pulmonary arterial hypertension'] @entity2348 :: ('MESH:D001424', 'Disease') :: ['bacterial sepsis'] @entity651 :: ('MESH:D055370', 'Disease') :: ['Pulmonary microvascular injury'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative Pseudomonas sepsis', 'postoperative septic shock'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity130 :: ('MESH:D014947', 'Disease') :: ['injury appears']
@entity86 :: (MESH:D019106,Disease) :: ['postoperative sepsis']
