@entity1832 ( @entity1832 ) accounts for 15-20% of all autopsy confirmed @entity303 in old age. Characteristic histopathological changes are intracellular @entity1832 and Lewy neurites, with abundant senile plaques but sparse neurofibrillary tangles. Core clinical features are fluctuating @entity73 , persistent @entity1833 and @entity21 ( @entity304 ). One of these core features has to be present for a diagnosis of possible @entity1832 , and two for probable @entity1832 . Supportive features are repeated falls, @entity1163 , transient @entity909 , @entity3326 , delusions and @entity1833 in other modalities. @entity1832 is clinically under-diagnosed and frequently misclassified as systemic @entity933 or @entity303 due to @entity195 or @entity66 . Therapeutic approaches to @entity1832 can pose difficult dilemmas in pharmacological management. Neuroleptic medication is relatively contraindicated because some @entity1 show severe @entity3326 , which is associated with increased morbidity and mortality. Antiparkinsonian medication has the potential to exacerbate @entity716 symptoms and may be relatively ineffective at relieving @entity21 . Recently there is converging evidence that treatment with cholinesterase inhibitors can offer a safe alternative for the symptomatic treatment of cognitive and neuropsychiatric features in @entity1832 . This review will focus on the clinical characteristics of @entity1832 , its differential diagnosis and on possible management strategies.

XXXX with lewy bodies--diagnosis and treatment.

@entity3326 :: ('MESH:D009459', 'Disease') :: ['neuroleptic sensitivity'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['cerebrovascular disease'] @entity304 :: ('MESH:D010302', 'Disease') :: ['parkinsonism'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementias', 'dementia'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment'] @entity1163 :: ('MESH:D013575', 'Disease') :: ['syncope'] @entity909 :: ('MESH:D014474', 'Disease') :: ['loss of consciousness'] @entity1833 :: ('MESH:D006212', 'Disease') :: ['visual hallucinations', 'hallucinations'] @entity1832 :: ('MESH:D020961', 'Disease') :: ['Lewy bodies', 'DLB', 'Dementia with Lewy bodies'] @entity716 :: ('MESH:D011605', 'Disease') :: ['psychotic'] @entity195 :: ('MESH:D000544', 'Disease') :: ["Alzheimer's disease"] @entity933 :: ('MESH:D003693', 'Disease') :: ['delirium'] @entity21 :: ('MESH:D001480', 'Disease') :: ['extrapyramidal motor symptoms']
@entity303 :: (MESH:D003704,Disease) :: ['Dementia']
