Thrombolysis is considered to be contraindicated in acute @entity385 secondary to @entity884 ( @entity884 ). We report a 12-year-old female who presented with acute dense right @entity1269 and @entity2026 . Cranial magnetic resonance imaging and angiography showed multiple diffusion-restricted lesions in the left hemisphere and absence of flow in the left internal carotid artery. She was treated with intra-arterial tissue plasminogen activator within 6 hours of her presentation. Subsequently she was diagnosed with @entity884 and underwent debridement of vegetations and patch repair of the mitral valve. The @entity1 did not have @entity548 following thrombolytic therapy or surgery. Pathological analysis of the @entity339 revealed mostly fibrin @entity715 . Follow-up imaging showed complete recanalization of the left internal carotid artery, and the @entity1 had a remarkable neurological recovery. This is the first case report of successful intra-arterial thrombolytic therapy in childhood @entity884 -related @entity64 . We believe that thrombolytic therapy contributed to a favorable outcome in our @entity1 and may be safe in selected @entity1 with childhood @entity884 -related acute @entity385 .

Bacterial endocarditis in a @entity1 presenting with acute arterial XXXX : should thrombolytic therapy be absolutely contraindicated?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral valve vegetations'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhagic complications'] @entity1269 :: ('MESH:D010291', 'Disease') :: ['hemiparesis'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['aphasia'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke'] @entity884 :: ('MESH:D004696', 'Disease') :: ['pneumococcal endocarditis', 'IE', 'infective endocarditis']
@entity385 :: (MESH:D002544,Disease) :: ['ischemic stroke']
