BACKGROUND: Doppler Tissue Imaging (DTI) has been evaluated in @entity299 and some @entity296 . In @entity1 with @entity472 ( @entity3257 ), left ventricular contraction is slowered. This study aimed to evaluate the possible role of the measurement of @entity2472 ( @entity2472 ) by DTI in the evaluation of @entity3257 severity. METHODS: The study population constitutes 30 @entity1 : 15 with @entity3257 (nine severe @entity3257 ) and 15 control subjects. All of them had normal systolic function, sinus rhythm, and absence of @entity299 of @entity616 . @entity2472 was defined as the time from the onset of the QRS complex to the beginning of the DTI systolic wave. The correlation between @entity2472 and aortic area obtained by continuity equation, as well as the diagnostic value of @entity2472 in the identification of severe @entity3257 were studied. RESULTS: @entity2472 was significantly increased in @entity1 with severe @entity3257 (98+/-27 versus 65+/-21 ms, p=0.024). There was a significant correlation between @entity2472 and aortic area (r=-0.56; p=0.035). The receiver operator characteristic curve of @entity2472 in the identification of severe @entity3257 yielded an area under the curve of 0.852 (95% confidence interval: 0.665-1.0). The two best cut-points were >73 ms (88% sensitivity, 77% specificity) and >85 ms (78% sensitivity, 83% specificity). A value of >41 ms had a 100% sensitivity, but only a 17% specificity, and >91 ms showed a 100% specificity, but only a 44% sensitivity. CONCLUSIONS: @entity2472 measured by pulsed-wave DTI is increased in @entity1 with @entity472 .

Isovolumic contraction time by pulsed-wave Doppler tissue imaging in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity296 :: ('MESH:D009202', 'Disease') :: ['cardiomyopathies'] @entity299 :: ('MESH:D006331', 'Disease') :: ['ischaemic heart disease'] @entity472 :: ('MESH:D001024', 'Disease') :: ['aortic stenosis'] @entity3257 :: ('MESH:C580335', 'Disease') :: ['and six non-severe', 'AS'] @entity616 :: ('MESH:D006327', 'Disease') :: ['conduction abnormalities'] @entity2472 :: ('MESH:C536214', 'Disease') :: ['isovolumic contraction time', 'ICT']
@entity472 :: (MESH:D001024,Disease) :: ['aortic stenosis']
