OBJECTIVE: The aim of this study was to determine which characteristics could better distinguish @entity1832 ( @entity1832 ) from @entity195 ( @entity195 ) at the @entity73 ( @entity73 ) stage, with particular emphasis on visual space and object perception abilities. METHODS: Fifty-three @entity1 with mild @entity73 that were eventually diagnosed with probable @entity1832 ( @entity73 ) and @entity195 ( @entity73 : n = 28) at a 3-year follow-up were retrospectively studied. At the first visit, the @entity1 underwent cognitive assessment including the Qualitative Scoring Mini Mental State Examination Pentagon Test and the Visual Object and Space Perception Battery. The @entity146 Inventory Questionnaire, Unified @entity191 Rating Scale (UPDRS) and questionnaires for @entity73 and @entity25 were also administered. RESULTS: The best clinical predictor of @entity1832 was the presence of soft extrapyramidal signs (mean UPDRS score: 4.04    5.9) detected in 72% of @entity1 , followed by @entity11755 (60%) and fluctuations (60%). Wrong performances in the pentagon's number of angles were obtained in 44% of @entity1832 and 3.7% of @entity195 @entity1 and correlated with speed of visual attention. Executive functions, @entity227 were worse in @entity1832 , while @entity73 was greater in @entity195 . @entity227 were present in both @entity73 and @entity195 . CONCLUSIONS: Poor performance in the pentagon's number of angles is specific of @entity1832 and correlates with speed of visual attention. The dorsal visual stream seems specifically more impaired in @entity73 with respect to the ventral visual stream, the latter being involved in both @entity1832 and @entity195 . These cognitive features, associated with @entity21 , should alert clinicians to a diagnostic hypothesis of @entity1832 .

Clinical and Cognitive Phenotype of Mild XXXX Evolving to Dementia with Lewy Bodies.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual attention and visuospatial abilities', 'Deficits in the visual-perceptual domain'] @entity146 :: ('MESH:D001523', 'Disease') :: ['Neuropsychiatric'] @entity73 :: ('MESH:D003072', 'Disease') :: ['MCI-DLB: n = 25', 'MCI-DLB', 'cognitive deficits', 'MCI-AD', 'MCI', 'mild cognitive impairment', 'cognitive fluctuations', 'verbal episodic memory impairment'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's Disease"] @entity1832 :: ('MESH:D020961', 'Disease') :: ['dementia with Lewy bodies', 'DLB'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"] @entity11755 :: ('MESH:D020187', 'Disease') :: ['REM sleep behavior disorder'] @entity21 :: ('MESH:D001480', 'Disease') :: ['subtle extrapyramidal signs'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep disorders']
@entity73 :: (MESH:D003072,Disease) :: ['Cognitive Impairment']
