BACKGROUND: The aim was to investigate the effect of @entity2399 on @entity282 and analgesic consumption after @entity1937 -based anesthesia. MATERIAL/METHODS: Forty @entity1 18 to 65 years old were enrolled in this prospective, randomized, double-blinded clinical study. The study solutions were randomly preoperatively prepared for groups M ( @entity1760 ) and R (normal saline). A bolus of 0.2 ml/kg of study solution (30 mg/kg @entity1760 or saline) was given before induction of anesthesia and infusion was started at a rate of 3.3 ml/h (500 mg/h @entity1760 or saline). A 1 microg/kg loading dose of @entity1937 following infusion was started at a rate of 0.25 micro g/kg/min, subsequently increasing stepwise by 0.05 micro g/kg/min increments if insufficient anesthesia was suspected. All postoperative outcome data were collected by an anesthesiologist who was blinded to the anesthetic regimen. @entity158 intensity using a visual analogue scale (VAS) was recorded for 24 hours postoperatively. RESULTS: Hemodynamic and respiratory variables such as diastolic and systolic blood pressure, heart rate, and @entity26 saturation were similar in both groups. The mean intraoperative @entity1937 consumption in groups M and R was similar. The VAS score was significantly lower in the @entity1760 group at 15 and 30 minutes postoperatively. Total @entity1286 consumption was significantly lower in the @entity1760 group than in the @entity1937 -alone group. CONCLUSIONS: It was concluded that @entity2399 decreased the postoperative @entity1286 requirement when @entity1937 was used for intraoperative @entity1337 .

XXXX reduces postoperative @entity1286 requirement after @entity1937 -based anesthesia.

@entity1 :: ('9606', 'Species') :: ['women'] @entity2399 :: ('MESH:D008278', 'Chemical') :: ['magnesium sulfate'] @entity1937 :: ('MESH:C071741', 'Chemical') :: ['remifentanil'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity282 :: ('MESH:D010149', 'Disease') :: ['postoperative pain'] @entity1760 :: ('MESH:D008274', 'Chemical') :: ['magnesium']
@entity2399 :: (MESH:D008278,Chemical) :: ['Magnesium sulfate']
