40 @entity1 (39 @entity1 and 1 @entity1 ) aged 13-66 years (mean 35.9 years) with solitary benign non-toxic thyroid nodule confirmed by clinical and hormonal examination, ultrasonography and fine needle aspiration biopsy, were treated with intranodular percutaneous 96% @entity1068 injection, performed under ultrasound guidance. There were 34 @entity1 with solid nodule (including 4 @entity1 ) with solitary nodule in recurrent goitre after thyroidectomy) and 6 @entity1 with cyst. The nodules were 7-60 mm (mean 31 mm) in diameter. 1 ml of @entity1068 was instilled per 1 cm3 of nodule tissue. 1-5 (mean 2.6) sessions were conducted at one month intervals. The early follow-up evaluation of the results (the evaluation of nodule size by means of clinical and ultrasound examination) was performed after 6 months, and the long-term one after 2 years since the last injection. A morphological evaluation was conducted according to the following scale: 1--nodule disappearance, 2--cicatricial nodule (solid structure in the ultrasonography and less than 0.5 cm in diameter), 3--nodule smaller by [symbol: see text] 50% of initial dimensions, 4--nodule smaller by < 50% of initial dimensions. A final follow-up evaluation revealed: nodule disappearance in 15 (37.5%) @entity1 (Group 1), cicatricial nodule in 10 (25%) @entity1 (Group 2), nodules smaller by [symbol: see text] 50% of initial dimensions in 7 (17.5%) @entity1 (Group 3) and nodules smaller by < 50% of initial dimensions in 8 (20%) @entity1 (Group 4). The results in Group 1 and 2 were defined as good (25 @entity1 --62.5%), in Group 3 as satisfactory (17.5%) and in Group 4 as @entity1835 . The results of treatment of cysts and nodules in recurrent goitre were good or satisfactory. The following complications were observed: 1) @entity158 during and after the injection in 29 (72.5%) @entity1 , 2) subfebrile body temperature ap to 38 degrees C in 4 (10%) @entity1 and fever up to 39 degrees C on the 1-st day after the injection in 2 (5%) @entity1 , 3) ecchymosis in 1 (2.5%) @entity1 , 4) temporary @entity7364 in 2 (5%) @entity1 , 6) temporary unilateral vocal @entity912 and @entity4820 in 1 (2.5%) @entity1 . It seems that percutaneous @entity1068 injection can be useful treatment method of solitary benign non-toxic thyroid nodules, both cysts and solid nodules, in @entity1 who do not consent to surgical treatment or with contraindications to an operation.

[The treatment of solitary thyroid nodules in non-toxic goiter with 96% XXXX injections].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'man'] @entity7364 :: ('MESH:D055154', 'Disease') :: ['dysphonia'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity1835 :: ('572', 'Gene') :: ['bad'] @entity912 :: ('MESH:D010243', 'Disease') :: ['cord paralysis'] @entity4820 :: ('MESH:D006732', 'Disease') :: ['temporary Horner syndrome']
@entity1068 :: (MESH:D000431,Chemical) :: ['ethanol']
