UNASSIGNED: Purpose: To investigate whether @entity8629 -induced @entity656 ( @entity656 ) in @entity35 could be noninvasively studied by clinical magnetic resonance imaging (MRI) techniques and validated by enzymatic biochemistry and histomorphology. Materials and Methods: The study was approved by the institutional animal ethical committee. The @entity656 was induced in 26 @entity35 by intraperitoneal injections of @entity8629 , as compared to 6 normal @entity35 . T2-weighted 3D MRI, T2 relaxation measurement and contrast enhanced T1-weighted MRI were performed at 3 Tesla. Pancreatic volume and contrast ratio of pancreas against surrounding tissues were measured by MRI. Animals were scarified at 3, 8, 24 and 48-hr respectively for analyses of serum @entity9112 and amylase levels, and biliopancreatic perfusion-assisted histomorphology. Results: The @entity656 could be observed on MRI 3-hr onwards after @entity8629 -administration. T2 relaxation within the pancreas was prolonged due to high water content or @entity4 . Increase of @entity455 was indicated by T1 contrast enhancement. Both @entity4 and @entity455 gradually recovered afterwards (p<0.05/0.01), paralleled by declining serum enzyme levels (p<0.05). Microscopy revealed cell vacuolization and @entity4 for early stage, and increased inflammatory cell infiltration and acinar cell loss after 24 and 48-hr. Conclusion: Multiparametric MRI techniques at 3.0T could facilitate noninvasive diagnosis and characterization of @entity8629 induced @entity656 in @entity35 , as validated by a novel ex vivo method.

Visualization, Quantification and Characterization of XXXX -Induced Acute Pancreatitis in @entity35 by 3.0T Clinical MRI, Biochemistry and Histomorphology.

@entity9112 :: ('291437(Tax:10116)', 'Gene') :: ['lipase'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular permeability'] @entity656 :: ('MESH:D019283', 'Disease') :: ['AP', 'acute pancreatitis'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity8629 :: ('MESH:D002108', 'Chemical') :: ['Caerulein']
@entity8629 :: (MESH:D002108,Chemical) :: ['Caerulein']
