PURPOSE: Colonoscopy is the preferred method for @entity14 surveillance of high-risk @entity1 . Despite its high sensitivity, @entity1127 or @entity5 may be undetected by colonoscopy and later attributed to an accelerated @entity2513 sequence. This study assesses how the characteristics of @entity14 found at intervals between surveillance relate to the @entity2513 sequence and its prevention. METHODS: The records of 557 @entity1 with @entity14 that were diagnosed from January 1, 1990, to December 31, 1996, were reviewed to identify those @entity1 who had prior colonoscopic surveillance within 60 months of their diagnosis. RESULTS: There were 29 (5.2 percent) @entity1 who had one or more colonoscopies before diagnosis of their @entity14 . Mean interval between diagnosis and prior colonoscopy was 23 (range, 4-59) months. The distribution of @entity5 included nine cecum, two ascending, three hepatic flexure, five transverse, one splenic flexure, three descending, two sigmoid, three rectum, and one anal canal. The mean @entity5 size was 4.4 cm for the cecum and 2.4 cm for all other locations. There were 7 Tis, 6 T1, 4 T2, and 12 @entity75 . Six @entity1 with @entity75 had prior colonoscopies within 24 months of the diagnosis. Three of four @entity1 with lymphatic metastases had @entity5 in the cecum. Twenty @entity5 (69 percent) were well or moderately differentiated. Mean follow-up was 41 (range, 7-95) months with two local recurrences and two unrelated @entity204 . CONCLUSIONS: Size, differentiation, and stage of @entity14 in addition to the interval to diagnosis suggest that the majority of @entity5 found during surveillance colonoscopy followed prior false-negative examinations. Because cecal landmarks are most constant, prior photographic documentation may help to prove or disprove fast growth of @entity5 found in the cecum during surveillance colonoscopy.

XXXX after surveillance colonoscopy: false-negative examination or fast growth?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1127 :: ('MESH:D011127', 'Disease') :: ['polyps'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancers', 'tumors'] @entity75 :: ('MESH:D001927', 'Disease') :: ['T3 lesions'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancers', 'colorectal cancer'] @entity2513 :: ('MESH:C563365', 'Disease') :: ['adenoma-carcinoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths']
@entity14 :: (MESH:D015179,Disease) :: ['Colorectal cancer']
