UNASSIGNED: Pharmaceuticals are increasingly detected in environmental matrices, but information on their trophic transfer in aquatic food webs is insufficient. This study investigated the bioaccumulation and trophic transfer of 23 pharmaceuticals in Taihu @entity17360 , China. Pharmaceutical concentrations were analyzed in surface water, sediments and 14 aquatic species, including plankton, invertebrates and fish collected from the @entity17360 . The median concentrations of the detected pharmaceuticals ranged from not detected (ND) to 49  ng/L in water, ND to 49  ng/g dry weight (dw) in sediments, and from ND to 130  ng/g dw in @entity33867 . Higher concentrations of pharmaceuticals were found in zoobenthos relative to plankton, shrimp and fish muscle. In fish tissues, the observed pharmaceutical contents in the liver and brain were generally higher than those in the gills and muscle. Both bioaccumulation factors (median BAFs: 19-2008  L/kg) and @entity33867 -sediment accumulation factors (median BSAFs: 0.0010-0.037) indicated a low bioaccumulation potential for the target pharmaceuticals. For eight of the most frequently detected pharmaceuticals in food webs, the @entity4059 ( @entity4059 ) were analyzed from two different regions of Taihu @entity17360 . The @entity4059 for @entity14698 , @entity1169 , @entity3522 , @entity5018 , @entity800 , @entity4258 , @entity2177 and @entity803 in the two food webs ranged from 0.28 to 1.25, suggesting that none of these pharmaceuticals experienced trophic magnification. In addition, the pharmaceutical @entity4059 did not differ significantly between the two regions in Taihu @entity17360 .

Bioaccumulation and trophic transfer of pharmaceuticals in food webs from a large freshwater XXXX .

@entity1169 :: ('MESH:D011433', 'Chemical') :: ['propranolol'] @entity4258 :: ('MESH:D009643', 'Chemical') :: ['norfloxacin'] @entity3522 :: ('MESH:D004008', 'Chemical') :: ['diclofenac'] @entity4059 :: ('MESH:D007020', 'Disease') :: ['trophic magnification factors', 'TMFs'] @entity33867 :: ('131567', 'Species') :: ['biota'] @entity5018 :: ('MESH:D007052', 'Chemical') :: ['ibuprofen'] @entity17360 :: ('83971', 'Species') :: ['Lake', 'lake'] @entity2177 :: ('MESH:D002939', 'Chemical') :: ['ciprofloxacin'] @entity14698 :: ('MESH:D015575', 'Chemical') :: ['roxithromycin'] @entity803 :: ('MESH:D013752', 'Chemical') :: ['tetracycline'] @entity800 :: ('MESH:D015242', 'Chemical') :: ['ofloxacin']
@entity17360 :: (83971,Species) :: ['lake']
