BACKGROUND: The 6-minute walk and heart rate variability have been used to assess mortality risk in @entity1 with @entity712 , but their relationship to each other and their usefulness for predicting mortality at 1 year are unknown. OBJECTIVE: To assess the relationships between the 6-minute walk test, heart rate variability, and 1-year mortality. METHOD: A sample of 113 @entity1 in advanced stages of @entity712 (New York Heart Association Functional Class III-IV, left ventricular ejection < 0.25) were studied. All 6-minute walks took place in an enclosed, level, measured corridor and were supervised by the same nurse. Heart rate variability was measured by using (1) a standard-deviation method and (2) Poincar   plots. Data on RR intervals obtained by using 24-hour Holter monitoring were analyzed. Survival was determined at 1 year after the Holter recording. RESULTS: The results showed no significant associations between the results of the 6-minute walk and the two measures of heart rate variability. The results of the walk were related to 1-year mortality but not to the risk of @entity944 . Both measures of heart rate variability had significant associations with 1-year mortality and with @entity944 . However, only heart rate variability measured by using Poincar   plots was a predictor of total mortality and risk of @entity944 , independent of left ventricular ejection fraction, serum levels of @entity1372 , results of the 6-minute walk test, and the standard-deviation measure of heart rate variability. CONCLUSIONS: Results of the 6-minute walk have poor association with mortality and the two measures of heart rate variability in @entity1 with advanced-stage @entity712 and a low ejection fraction. Further studies are needed to determine the optimal clinical usefulness of the 6-minute walk and heart rate variability in @entity1 with advanced-stage @entity712 .

Six-minute walk test and heart rate variability: lack of association in advanced stages of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity944 :: ('MESH:D003645', 'Disease') :: ['sudden death']
@entity712 :: (MESH:D006333,Disease) :: ['heart failure']
