OBJECTIVES: Paraneoplastic @entity16 (PNS) constitute a challenging diagnostic problem, as the underlying @entity5 often remains unidentified for a long time, even with frequent conventional diagnostic procedures. For appropriate @entity1 management timely identification of the @entity5 is critical. We evaluated the value of @entity419 -PET/CT in the investigation of PNS. METHODS: The case notes of 46 consecutive @entity1 with clinically suspected PNS who underwent @entity419 -PET/CT were reviewed retrospectively and the performance of PET/CT for detecting underlying @entity5 was assessed. RESULTS: PET/CT detected foci of increased @entity419 uptake in 10 out of 46 @entity1 . In six of these 10 @entity1 combined PET/CT identified the underlying disease: four @entity1 suffered from PNS; vasculitic and local metastatic disease was detected in two other @entity1 . CONCLUSIONS: Based on our results, we believe that the role of positron emission tomography in the detection of occult @entity5 in @entity1 with PNS has been overestimated in the past. In clinical practice, PNS is far more often suspected than proven. In our study combined PET/CT identified @entity5 as the underlying cause of suspected PNS in only 8.7% (4/46). We believe that combined PET/CT should be reserved for stringently selected @entity1 with a high clinical index of suspicion for PNS and after conventional imaging techniques fail to detect a @entity5 .

XXXX -PET/CT in the diagnosis of @entity16 : a retrospective analysis.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumours', 'neoplasms', 'malignancy', 'tumour'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological syndromes'] @entity419 :: ('MESH:D019788', 'Chemical') :: ['(18)F-FDG']
@entity419 :: (MESH:D019788,Chemical) :: ['18F-FDG']
