PURPOSE: To develop a technique for high resolution, four-dimensional (4D), multiphase, steady-state imaging with contrast enhancement (MUSIC) in @entity1 with complex @entity299 . METHODS: Eight pediatric @entity1 underwent cardiovascular MRI with controlled mechanical ventilation after @entity3703 administration. Breath-held contrast-enhanced MRA (CE-MRA) was performed during the first-pass and delayed phases of @entity3703 , followed by a respiratory gated, 4D MUSIC acquisition during the steady state distribution phase of @entity3703 . The subjective image quality and image sharpness were evaluated. Assessment of ventricular volumes based on 4D MUSIC was compared with those based on multislice 2D cardiac cine MRI. RESULTS: The 4D MUSIC technique provided cardiac-phase-resolved (65-95 ms temporal resolution) and higher spatial resolution (0.6-0.9 mm isotropic) images than previously achievable using first-pass CE-MRA or 2D cardiac cine. When compared with @entity3703 -based first-pass CE-MRA, the 4D MUSIC provided sharper images and better definition of the coronary arteries, aortic root, myocardium, and pulmonary trunk (P   <   0.05 for all). The ventricular volume measurements were in good agreement between 4D MUSIC and 2D cine (concordance correlation coefficient >0.95). CONCLUSION: The 4D MUSIC technique may represent a new paradigm in MR evaluation of cardiovascular anatomy and function in @entity1 with complex @entity299 . Magn Reson Med 74:1042-1049, 2015.    2014 Wiley Periodicals, Inc.

Four-dimensional, multiphase, steady-state imaging with contrast enhancement (MUSIC) in the heart: A feasibility study in XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity3703 :: ('MESH:D052203', 'Chemical') :: ['ferumoxytol', 'Ferumoxytol'] @entity299 :: ('MESH:D006331', 'Disease') :: ['congenital heart disease']
@entity1 :: (9606,Species) :: ['children']
