OBJECTIVE: This study compares mortality from type 1 @entity6 in Japan and Finland and examines the effects of sex, age at diagnosis, and calendar time period of diagnosis on mortality. RESEARCH DESIGN AND METHODS: @entity1 with type 1 @entity6 from Japan (n = 1,408) and Finland (n = 5,126), diagnosed from 1965 through 1979, at age <18 years, were followed until 1994. Mortality was estimated with and without adjustment for that of the general population to assess absolute and relative mortality using Cox proportional hazard models. RESULTS: Overall mortality rates in Japan and Finland were 607 (95% CI 510-718) and 352 (315-393), respectively, per 100,000 @entity1 -years; standardized mortality ratios were 12.9 (10.8-15.3) and 3.7 (3.3-4.1), respectively. Absolute mortality was higher for @entity1 than for @entity1 in Finland, but relative mortality was higher for @entity1 than for @entity1 in both cohorts. Absolute mortality was higher in both cohorts among those whose @entity6 was diagnosed during puberty, but relative mortality did not show any significant difference by age at diagnosis in either cohort. In Japan, both absolute and relative mortality were higher among those whose diagnosis was in the 1960s rather than the 1970s. CONCLUSIONS: Mortality from type 1 @entity6 was higher in Japan compared with Finland. The increased risk of death from type 1 @entity6 seems to vary by sex, age at diagnosis, and calendar time period of diagnosis. Further investigation, especially on cause-specific mortality, is warranted in the two countries.

Long-term mortality in nationwide cohorts of childhood-onset type 1 XXXX in Japan and Finland.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'person', 'men'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes']
