The prognosis for @entity1 with @entity712 ( @entity712 ) is poor, with a mortality exceeding 50% within 5 years from diagnosis. This poor prognosis remains despite improved pharmacological therapy. Because the prevalence of @entity944 among these @entity1 is high, reported to exceed 40%, the prognostic importance of @entity1165 has attracted much interest. Long-term electrocardiographic monitoring of @entity1 with @entity712 reveals a high prevalence of @entity1540 , which in many @entity1 occur frequently or are complex according to Lown criteria. @entity1165 (three or more consecutive beats) has been recorded in 40% or more of the @entity1 population. Whether the occurrence and/or severity of @entity1165 detected on Holter electrocardiograms relates to the subsequent prognosis is, however, debated. The occurrence of @entity1165 may just be an expression of severely compromised left ventricular function, which, in turn, decides the subsequent outcome of the disease. Besides @entity296 , @entity1 with @entity712 have many factors that may contribute to the high prevalence of @entity943 . Among these are elevated levels of plasma @entity1063 . @entity2178 may increase the sensitivity to sympathetic nervous system arousal but also promotes renal loss of @entity972 and @entity1760 . Treatment with digitalis and diuretic drugs may provoke @entity943 as well. @entity712 therapy may, however, also improve @entity943 . Accordingly, it has been demonstrated that @entity3371 therapy significantly reduces ventricular prematurity, compared with digitalis. In contrast, however, @entity4688 improvement of mortality was due to a reduction of progressive @entity712 , with no difference seen in the incidence of @entity1164 (the CONSENSUS study).(ABSTRACT TRUNCATED AT 250 WORDS)

Effect of @entity712 treatment on incidence and prognosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['patient', 'patients'] @entity1164 :: ('MESH:D016757', 'Disease') :: ['sudden cardiac death'] @entity4688 :: ('MESH:D004656', 'Chemical') :: ['enalapril'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure', 'congestive heart failure', 'CHF', 'Heart failure'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['Ventricular tachycardia', 'ventricular tachyarrhythmias', 'ventricular tachyarrhythmia'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial injury'] @entity944 :: ('MESH:D003645', 'Disease') :: ['sudden death'] @entity2178 :: ('183', 'Gene') :: ['Angiotensin II'] @entity3371 :: ('CHEBI:3380', 'Chemical') :: ['captopril'] @entity1540 :: ('MESH:D018879', 'Disease') :: ['ventricular premature beats'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity1063 :: ('MESH:D009638', 'Chemical') :: ['norepinephrine'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmias', 'arrhythmias'] @entity1760 :: ('MESH:D008274', 'Chemical') :: ['magnesium']
@entity1165 :: (MESH:D017180,Disease) :: ['ventricular tachyarrhythmias']
