It is thought that the risk of @entity1373 ( @entity1373 ) increases with age, particularly among postmenopausal @entity1 . Three hypotheses were investigated to try to explain this phenomena: use of hormone replacement therapy (HRT), increased @entity0 screening and improvements in radiological quality. Data were collected from the Bouches du Rh  ne @entity0 screening programme database and from the pathological registry of all @entity1 operated on for @entity1558 in the district. The @entity1373 incidence rate was studied using a Poisson regression analysis. The change in the profile of @entity1558 was explored through studying changes in the proportion of @entity1373 among benign lesions and @entity5 . The @entity1373 incidence rate significantly increased over time (13.6% per year). The proportion of @entity1373 among the benign diseases increased with time and was significantly higher for HRT users (Odds Ratio (OR)=2.05; 95% Confidence Interval (CI): 1.43-2.93). While @entity1373 decreased with age among HRT non-users, it increased among users as a proportion of both benign and malignant lesions. The @entity1373 incidence rate significantly increased among pre- and postmenopausal @entity1 . Our study suggests that this increase is partly explained by the incidental discovery of these lesions by mammography and partly by a real increase of the disease among HRT users.

Does hormone replacement therapy increase the frequency of @entity0 in postmenopausal XXXX ? Results from the Bouches du Rhone district screening campaign.

@entity1 :: ('9606', 'Species') :: ['women'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant diseases'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['AH', 'atypical hyperplasia'] @entity1558 :: ('MESH:D001941', 'Disease') :: ['breast diseases']
@entity1 :: (9606,Species) :: ['women']
