UNASSIGNED: "No reflow" phenomenon is a common complication with significant prognostic repercussions after reperfused acute @entity583 . Previous studies have shown the feasibility and prognostic significance of coronary microcirculation assessment  by transthoracic Doppler of left anterior descending artery (LAD). The aim of the study was to evaluate the time course of  the coronary microcirculation status after acute anterior @entity583 reperfused by primary angioplasty with stent on  LAD. MATERIAL AND METHODS: Twenty-three @entity1 underwent transthoracic echocardiography at 3 days (M0) and one month  (M1) after reperfusion, with LAD flow analysis (peak systolic and diastolic velocities, diastolic deceleration time and systolic  flow reversal). The @entity1 were divided into two groups, of good reperfusion and "no reflow", by a 600 ms cut-off of the M0  diastolic deceleration time, previously shown to best discriminate between the two microvascular reperfusion states. RESULTS:   Of all @entity1 , 21 survived to M1 and were included in analysis. @entity3885 , as defined, was present in 50% of @entity1 at M0 and it was associated with significantly worse ejection fraction both at M0 and M1 (p=0.01 and 0.04, respectively). Killip class at admission was the only independent predictor of "no reflow". @entity318 increased from 661.9  339.3 at M0 to 948.2  201.8 at M1 (p=0.0003). In @entity1 with initial "no reflow", DDT increased to normal values at M1 (876.2  167.7 vs. 346.3  133.9 at M0, p<0.0001). In these @entity1 , the PDV/PSV ratio decreased at one month (1.91  0.37 vs. 2.70  1.22, p=0.06), by decrease of PDV (0.29  0.06 vs. 0.40  0.19, p=0.03). CONCLUSIONS: The parameters of coronary microcirculatory impedance improve significantly at one month after @entity1188 , suggesting delayed full reversibility of the @entity3885 .

Serial transthoracic coronary Doppler shows complete reversibility of XXXX pattern at one month after reperfused acute @entity583 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity318 :: ('MESH:D003634', 'Chemical') :: ['DDT'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['microvascular obstruction', 'Microvascular obstruction'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarction'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'myocardial  infarction']
@entity3885 :: (MESH:D008173,Disease) :: ['microvascular obstruction']
