INTRODUCTION: Infections are an important preventable cause of @entity204 in @entity5 @entity1 . The aim of this study was to clarify the epidemiologic characteristics and resistance patterns of causative isolates and mortality predictors in @entity5 @entity1 . METHODOLOGY: @entity1 with sterile site infections were evaluated in a retrospective cohort study. Etiological agents, antimicrobial resistance patterns of the isolates, and possible risk factors for mortality were recorded. Survivors and non-survivors on day 30 after each @entity281 onset were compared to identify the predictors of mortality. RESULTS: A total of 205 @entity281 episodes of 132 @entity1 were included in this study. Of them, 75% had @entity1583 and 25% had solid @entity5 . Febrile @entity1398 was diagnosed in 61.5%. Bloodstream infections were the most frequent @entity281 (78%). The majority of the pathogens were Enterobacteriaceae (44.3%) and nonfermentative isolates (17.6%). @entity281 were responsible for 40% of the episodes. The mortality rate was 23.4%. Inadequate initial antibiotic treatment (OR = 4.04, 95% CI = 1.80-9.05, p = 0.001), prolonged @entity1398 (> 7 days) before @entity281 (OR = 3.61, 95% CI = 1.48-8.80, p = 0.005), @entity281 due to Klebsiella species (OR = 3.75, 95% CI = 1.31-10.7, p = 0.013), and @entity3064 (OR = 5.00, 95% CI = 1.38-18.2, p = 0.014) were independent predictors of mortality. CONCLUSIONS: Gram-negative isolates were found to be the predominant pathogens with higher mortality rates. Local epidemiological data should be taken into account when administering empirical therapy since the inadequacy of initial antibiotherapy is associated with a poor outcome.

Emergence of multidrug resistant isolates and mortality predictors in XXXX with solid @entity5 or @entity1583 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors', 'infections of cancer', 'cancer'] @entity3064 :: ('470', 'Species') :: ['Acinetobacter baumannii'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'Multidrug-resistant (MDR) infections'] @entity1398 :: ('MESH:D009503', 'Disease') :: ['neutropenia'] @entity1583 :: ('MESH:D019337', 'Disease') :: ['hematologic malignancies'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1 :: (9606,Species) :: ['patients']
