OBJECTIVE: To evaluate the effectiveness of intravenous immunoglobulin (IVIG) treatment of @entity573 >= 10 days after illness onset. METHODS: We selected @entity1 initially treated with IVIG on days 11 to 20 in the database of the 20th nationwide survey in Japan. We then selected pair-matched control subjects of the same gender and age, who were initially treated with IVIG on days 4 to 8 with the same dose at the same institutions. We compared the proportions of additional treatments and @entity453 ( @entity453 ) between the groups. We also compared fractional changes in various laboratory data before and after IVIG. Fractional change was defined as follows: (Y - X)/X, in which X represents the data before treatment and Y the data after treatment. RESULTS: One hundred fifty @entity1 (75 pairs) were studied. The proportion of @entity1 who received additional treatments among those given initial IVIG after days 10 was slightly lower than those treated earlier (12% vs 16%). The fractional changes in the white blood cell count, % neutrophils, and @entity1851 were similar. Among all @entity1 , the proportions of @entity453 during the convalescent phase were significantly higher in the late than in the early group (27% vs 1%). Among @entity1 who had not developed @entity453 before initial treatment, the proportions with @entity453 during the acute phase were similar (8% vs 8%). CONCLUSIONS: IVIG treatment >= 10 days after illness onset achieves @entity32 but was found to be insufficient for preventing @entity453 .

Late intravenous immunoglobulin treatment in XXXX with @entity573 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['resolution of inflammation'] @entity573 :: ('MESH:C537014', 'Disease') :: ['Kawasaki disease'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CALs', 'coronary artery lesions'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein']
@entity1 :: (9606,Species) :: ['patients']
