As @entity1 with @entity299 grow older, @entity956 becomes more prevalent. A collaborative study was performed in 19 institutions to determine the clinical characteristics of these @entity1 and the factors affecting prognosis. There were 380 @entity1 with one or more electrocardiographically documented episodes of @entity956 that first occurred between ages 1 and 25 years (mean age at onset 10.3). Episodes of flutter continued to occur for a mean of 2.5 years after the onset. Of the 380 @entity1 , 60% had repaired @entity299 , 13% palliated @entity299 , 8% unoperated @entity299 , 8% an otherwise normal heart, 6% @entity296 , 4% rheumatic @entity299 and 2% other lesions. Overall, drugs were effective in eliminating @entity956 in 58% of @entity1 ; specifically, @entity2643 and @entity6838 plus @entity5126 were effective in 53%, digoxin alone in 44% and @entity1169 in 21%. @entity2643 was effective in seven (78%) of nine @entity1 . Corrective surgery was performed after the onset of @entity956 in 66 @entity1 ; in 52% the @entity956 was easier to control or it resolved and in only 4% it was worse. At follow-up (mean 6.5 years), 83% of the @entity1 were alive (49% without @entity956 and 34% with @entity956 ) and 17% died (10% suddenly, 6% of nonsudden cardiac cause and 1% of noncardiac cause). @entity204 occurred in 20% of those for whom an effective drug could not be found to eliminate @entity956 compared with 5% of those who were treated with an effective drug (p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

XXXX in the young: a collaborative study of 380 cases.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity1169 :: ('MESH:D011433', 'Chemical') :: ['propranolol'] @entity2643 :: ('MESH:D000638', 'Chemical') :: ['amiodarone', 'Amiodarone'] @entity296 :: ('MESH:D009202', 'Disease') :: ['cardiomyopathy'] @entity6838 :: ('MESH:D004077', 'Chemical') :: ['digoxin'] @entity956 :: ('MESH:D001282', 'Disease') :: ['atrial flutter'] @entity5126 :: ('MESH:D011802', 'Chemical') :: ['quinidine'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac disease', 'heart disease', 'congenital heart disease'] @entity204 :: ('MESH:D003643', 'Disease') :: ['Cardiac death']
@entity956 :: (MESH:D001282,Disease) :: ['Atrial flutter']
