The growing problem of widespread @entity1800 is a challenge for modern medicine. Emerging reports of @entity778 in Europe create a new epidemic problem. The virus responsible for causing the symptoms of the disease is transmitted by mosquitoes. Over 50% of the world's population lives in areas where the risk of @entity779 high. In total, according to WHO, infected with @entity779 is 2.4 million @entity1 and outbreaks of @entity66 are present in 100 countries that threaten the 2.5 billion population. There are four serotypes of @entity778 , which belong to the family Flaviviridae and the type of Flavirus. Serotypes are known as DENV-1, DENV-2, DENV-3 and DENV-4. Contact each of the serotypes of the virus causes long-lasting resistance to the other, and each of them is responsible for the induction of disease epidemics, including severe cases. In the first stage of the disease should seek to replace lost fluids and electrolytes. Because of the elevated body temperature is recommended to administer @entity1443 formulations and the use of cold compresses. Contraindicated is the use of @entity117 and non-steroidal anti-inflammatory drugs. In severe forms of @entity779 @entity1 absolutely should be hospitalized and treatment in the intensive care centers. In the treatment of shock, it is recommended that the administration of isotonic crystalloid fluids at 5-10 ml/kg/hr. under the control of hematocrit and fill peripheral microcirculation. The administration of blood products for the large current is required to control @entity548 . Dengue vaccine containing @entity108 - @entity108 chimeras is still at the stage of preclinical studies.

[Modern immunological and clinical determinants of XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients', 'people'] @entity778 :: ('MESH:D015658', 'Disease') :: ['dengue virus', 'dengue virus infections'] @entity108 :: ('CHEBI:34873', 'Chemical') :: ['DEN'] @entity66 :: ('MESH:D004194', 'Disease') :: ['endemic diseases'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['paracetamol'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral infections'] @entity779 :: ('MESH:D003715', 'Disease') :: ['dengue feveris', 'dengue']
@entity778 :: (MESH:D015658,Disease) :: ['virus dengue infection']
