OBJECTIVE: To assess the effect of @entity46 and radical laparoscopic excision on the quality of life of @entity1 with this condition. DESIGN: A prospective study. SETTING: The Northern Endometriosis Centre at South Cleveland Hospital, Middlesbrough and St. James's University Hospital, Leeds. POPULATION: Fifty-seven consecutive @entity1 undergoing laparoscopic excision of invasive @entity46 . METHODS: Questionnaires, both pre-operatively and four-month post-operatively, for a number of different symptoms associated with @entity46 were completed by @entity1 . Details of fertility, previous treatments and quality of life as measured by SF12 and EuroQOL (EQ-5D) and sexual activity questionnaire, as well as linear @entity158 scores for several symptoms, were recorded. Details of intra-operative findings was also collected. MAIN OUTCOME MEASURES: Effect of laparoscopic excision on @entity158 scores and quality of life, operative findings, type of surgery, length of surgery and incidence of intra- and post-operative complications. RESULTS: @entity1 with @entity46 were severely ill with significant @entity158 and impairment of quality of life and sexual activity. Four months after radical laparoscopic excision for deep @entity46 there was significant improvement in all the parameters measured including their quality of life based on EuroQOL evaluation: EQ-5D (0 x 595:0 x 729, P = 0 x 002) and EQ thermometer (68 x 9:77 x 7, P = 0 x 008); SF12 physical score (44 x 8:51 x 9, P = 0 x 015); sexual activity (habit P = 0 x 002, pleasure P = 0 x 002 and discomfort P < or = 0 x 001). Only the mental health score of SF12 failed to show any statistical improvement (47 x 1:48 x 4, P = 0 x 84). Symptomatically, there was a significant reduction in dysmenorrhoea (median 8 x 0:4 x 0, P < or = 0 x 001), pelvic @entity158 (median 7 x 0:2 x 0, P < or = 0 x 001), @entity546 (median 6 x 0:0 x 0, P < 0 x 001) and @entity158 scores (median 4 x 0:0 x 0, P < 0 x 001). Complications were noted, but were deemed to be acceptable for the extent of the surgery. CONCLUSIONS: This is an early analysis of the first 57 cases studied, but structured evaluation suggests that meaningful improvements in clinical symptoms and quality of life can be obtained with this approach with acceptable levels of operative morbidity. Further follow up of this series is required, but early evidence would suggest that the technique should be further evaluated as part of a randomised trial.

The effect of XXXX and its radical laparoscopic excision on quality of life indicators.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity546 :: ('MESH:D004414', 'Disease') :: ['dyspareunia'] @entity46 :: ('MESH:D004715', 'Disease') :: ['endometriosis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['rectal pain', 'pain']
@entity46 :: (MESH:D004715,Disease) :: ['endometriosis']
