INTRODUCTION: @entity9488 are common in @entity1 and adults and usually lead to a mild, self-limiting disease. Perinatally acquired @entity9488 , however, may lead to a severe disease including @entity693 , @entity198 , @entity99 , @entity1003 or @entity2401 . The mode of transmission may be not obvious. METHODS: 2 cases of neonatal @entity693 are presented. The disease was probably transmitted by the parents after birth during rooming-in within the hospital. The frequency of neonatal @entity9488 in Germany was determined by analysing data of the @entity9488 of the national commission for polio eradication. RESULTS: In both cases, the parents suffered from a @entity281 . In case 1, transmission by the febrile mother was suspected. In case 2, transmission of Coxsackie B5-virus by the father was confirmed by viral culture. Both neonates exhibited fever, one @entity1 had the typical clinical signs of @entity693 . Levels of inflammatory indicators in blood (CRP, @entity650 ) were remarkably low. From 2006 to 2009, 322 neonates were included within the voluntary, passive @entity9488 . In 81 @entity1 (25%) an enterovirus was detected via RT-PCR. The yearly frequency of @entity281 was between 8 and 21. In 58 of 322 specimens (18%) serotyping was possible. CONCLUSION: Infections with enterovirus are both clinically and epidemiologically relevant during the neonatal period. Predominantly in the typical season, from June to October, @entity281 may be an important differential diagnosis to @entity295 . The @entity281 may be transmitted via infected parents during rooming-in within the hospital.

[Neonatal XXXX : transmission via parents during rooming-in and current epidemiology in Germany].

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity650 :: ('3569', 'Gene') :: ['IL-6'] @entity9488 :: ('MESH:D004769', 'Disease') :: ['Non-polio-enterovirus infections', 'enterovirus surveillance system', 'enterovirus infections'] @entity295 :: ('MESH:D018805', 'Disease') :: ['neonatal sepsis'] @entity198 :: ('MESH:D004660', 'Disease') :: ['encephalitis'] @entity1003 :: ('MESH:D001778', 'Disease') :: ['coagulopathy'] @entity693 :: ('MESH:D008581', 'Disease') :: ['enterovirus meningitis', 'meningitis'] @entity281 :: ('MESH:D007239', 'Disease') :: ['febrile infection', 'infection', 'infections', 'enteroviral infections'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatitis'] @entity2401 :: ('MESH:D009205', 'Disease') :: ['myocarditis']
@entity693 :: (MESH:D008581,Disease) :: ['enterovirus meningitis']
