OBJECTIVE: To examine the longitudinal associations between caregiver strain and @entity1 ' clinical and psychosocial characteristics as well as caregivers' psychosocial characteristics. METHODS: At 4-month intervals during the 12   months study period, longitudinal data on caregiver strain and @entity1 and caregiver factors potentially associated with caregiver strain were collected from 126 couples, who participated in a randomised controlled trial on the effectiveness of case management in @entity746 ( @entity746 ). Caregiver strain was assessed with the Caregiver Strain Index (CSI). @entity1 and caregiver factors included sociodemographic characteristics, distress, coping style and perceived quality of care, as well as the @entity1 's functional status and emotional functioning. Multilevel regression analyses were performed. RESULTS: Caregiver strain increased significantly during the study period (b=0.315 points/months, p<0.001) and was significantly associated with @entity1 time-dependent factors functional status (b=-0.131 points/months, p<0.001) and emotional functioning (b=0.022 points/months, p=0.03), and caregiver time-dependent factors passive coping style (b=0.152 points/months, p=0.03), symptoms of @entity148 (b=0.186 points/months, p<0.001) and perceived quality of care for the caregiver (b=-0.452 points/months, p<0.001). CONCLUSIONS: Our study has identified that apart from the @entity1 's @entity717 and emotional well-being, a passive coping style of the caregiver, increased symptoms of @entity148 and feeling less supported by the @entity746 -team impact on caregiver strain. The multidisciplinary teams involved with the care of @entity1 with @entity746 need to be aware of these factors and increase their attention for the caregiver. This will help guide the development of evidence-based supportive interventions that focus on caregiver's coping style and avoiding distress. TRIAL REGISTRATION NUMBER: Netherlands Trial Register, number NTR1270.

Factors related to caregiver strain in XXXX : a longitudinal study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patient'] @entity717 :: ('MESH:D009069', 'Disease') :: ['physical disability'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity746 :: ('MESH:D000690', 'Disease') :: ['ALS', 'amyotrophic lateral sclerosis']
@entity746 :: (MESH:D000690,Disease) :: ['ALS']
