PURPOSE: The ideal pathological margin in @entity957 ( @entity957 ) is still debated. Our aim was to analyze the value of @entity5 -free pathological margin distance with regard to local recurrence in @entity957 . METHODS: We analyzed a series of 205 @entity1 who were treated for @entity957 from January 1980 to November 2007. @entity1 were categorized into 3 groups, based on pathological free margin (PFM): <3  mm (n  =  18); >= 3 and <8  mm (n  =  61); and >= 8  mm (n  =  126). RESULTS: The median age was 69 years. The median PFM was 10  mm (range: 1-65). Of 168 @entity1 who underwent lymphadenectomy, 64 (38.1%) developed LN @entity3 . After a median follow-up of 36.2 months, 78 (38%) cases recurred-47 (60.2%) experienced a local recurrence (LR). LR occurred in 16.7% of @entity1 with a PFM of <3  mm, 24.6% with a PFM >= 3 and <8  mm, and 22.2% of those with a PFM >= 8  mm (p  =  0.77). PFM did not correlate with LR when analyzed continuously (p  =  0.98). The 5-year disease-free survival (DFS) for LR was 79.6%. Margin distance did not negatively impact DFS (p  =  0.94); the presence of perineural invasion was the only variable that negatively influenced DFS (p  =  0.009). CONCLUSIONS: Although our results suggest no correlation between LR and pathological margin distance, the @entity5 -free resection margin remains significant with regard to locoregional control in @entity5 . A more conservative surgical approach may be considered in certain situations, such as margins near the clitoris, urethra, and anus.

How important is the pathological margin distance in XXXX ?

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'vulvar cancer'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity957 :: ('MESH:D002294', 'Disease') :: ['VSCC', 'vulvar squamous cell carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity5 :: (MESH:D009369,Disease) :: ['vulvar cancer']
