OBJECTIVE: To compare the outcome of labor in grandmultiparous @entity1 (para >5) who had induction of labor with @entity1421 vaginal tablets with grandmultiparous @entity1 in spontaneous labor, and to observe the complications during induction of labor. METHODS: A retrospective case control study was carried out at King Faisal Military Hospital, Khamis Mushayt between January 1993 through until December 1994. This included 64 grandmultiparous @entity1 that were induced with @entity1421 vaginal tablets. Ninety grandmultiparous @entity1 who went into labor spontaneously served as controls. Maternal and fetal data extracted from their hospital record files included age, parity, indication for induction, Bishop score at induction, total dose of @entity3009 used and complications of induction of labor. Other information were length of labor, need for syntocinon augmentation, @entity190 during the 3rd stage of labor, mode of delivery, birth weight, sex and Apgar score at 10 minutes. RESULTS: No serious complication of induction of labor such as rupture of the uterus was noted in the subjects studied. There were no significant differences when the mean age and parity of @entity1 in the 2 groups were compared (P>0.05) but there was difference in the gestational age at delivery (p=0.00). There was no significant difference in the mean length of first and 2nd stages of labor. The cesarean section rate was 11% and 8% in the cases and controls, while the need for syntocinon augmentation was twice in the cases than controls, 27% vs 14%. These were not statistically significant. CONCLUSION: We conclude that induction of labor with @entity1421 vaginal tablets may not have adverse effect on the outcome of labor compared with @entity1 in spontaneous labor. It may be safe to use @entity1421 vaginal tablets for induction of labor in the grand- multiparae. We recommend a randomized prospective trial to validate these observations.

A comparison of spontaneous labor with induced vaginal tablets XXXX in grand multiparae.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1421 :: ('MESH:D015232', 'Chemical') :: ['prostaglandin E2'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity3009 :: ('CHEBI:26333', 'Chemical') :: ['prostaglandin']
@entity1421 :: (MESH:D015232,Chemical) :: ['prostaglandin E2']
