OBJECTIVES: This study was conducted to provide a review of the prognostic factors of @entity189 . DESIGN: A retrospective analysis. SETTING/ @entity1 : @entity1 with @entity957 , treated in Northern Alberta, at the @entity5 Institute from 1975 to 1995 were analyzed using a population-based, @entity135 registry. There were 102 @entity1 , 73 male and 29 female, ranging in age from 35 years to 83 years, with a mean of 60 years. The clinical stages were T1: 5 @entity1 ; T2: 27 @entity1 , T3: 33 @entity1 ; T4: 11 @entity1 ; and Tx: 3 @entity1 . The nodal stages were N0: 33 @entity1 , N1: 26 @entity1 ; N2: 34 @entity1 , N3: 7 @entity1 ; Nx: 2 @entity1 . METHOD: The @entity1 were treated with various modalities: surgery alone: 2 @entity1 ; surgery plus radiation: 26 @entity1 ; radiation treatment alone: 61 @entity1 ; and others: 13 @entity1 . @entity1 were classified according to the UICC TNM 1992 criteria. The overall 5-year Kaplan-Meier survival in our series was 39%. The cause-specific 4-year survival was 57%. Various prognostic factors and their impact on survival were studied. RESULTS: On univariate analysis, the following factors were found to be significant. Age < 50 vs. > 50 (p = .02); endophytic growth pattern vs. exophytic growth of the primary (p = .01); @entity1066 vs. nonulcerated lesions (p = .000); various T stages (p = .003); clinical extension vs. no extension of @entity66 (p = .02); combined modality of treatment (surgery and radiation treatment) had the best chance of survival compared to radiation treatment alone (p = .03). Nodal stages N0 vs. N+ disease (p = .2); sex of the @entity1 , female vs. male (p = .83); and dose of radiation treatment < 5000 cGy vs. > 5000 cGy (p = .41) were found not to be significant. When the above significant factors were stratified according to the stage of the disease, only two were significant; @entity1066 vs. nonulcerated lesions (p = .04), and the modality of treatment chosen (e.g., radiation alone vs. radiation plus surgery) (p = .02). CONCLUSIONS: In this series of @entity1 , combined-modity approach using surgery and radiation treatment was found to be the best way to treat @entity189 . However, each treatment strategy should be individualized taking into account various prognostic factors.

XXXX : prognostic factors.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'PATIENTS'] @entity135 :: ('MESH:D006258', 'Disease') :: ['head and neck cancer'] @entity66 :: ('MESH:D004194', 'Disease') :: ['primary disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cross Cancer'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma of the tonsil'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcerated lesions'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma of the tonsil', 'tonsillar carcinoma']
@entity189 :: (MESH:D002277,Disease) :: ['Carcinoma of the tonsil']
