UNASSIGNED: In @entity8 , the presence of antibodies against M-type phospholipase A2 receptor is considered highly specific for idiopathic forms. However, no specific association to a particular clinical profile has been found for such antibodies. OBJECTIVE: To assess potential differences in initial clinical profile, course and prognosis of @entity8 depending on the presence of anti- @entity8164 antibodies. METHODS: Eighty-five @entity1 with @entity8 were included (55 anti- @entity8164 -positive and 30 anti- @entity8164 -negative). Clinical, biochemical and pathological variables were recorded at the time of diagnosis. Frequency of spontaneous remission, incidence of response to first-line therapy, frequency and number of recurrences, survival of renal function free from renal replacement therapy, survival of renal function free from @entity740 and frequency of occurrence of malignant, infectious or @entity792 during follow-up were recorded. RESULTS: At the time of diagnosis, anti- @entity8164 -negative @entity1 were significantly older and had a higher frequency of spontaneous remission. No differences were noted in the response to first-line treatment, frequency and number of recurrences, survival of renal function free from renal replacement therapy, or survival of renal function free from @entity740 . CONCLUSIONS: Anti- @entity8164 -negative @entity1 with @entity8 were older and experienced spontaneous remission more often than anti- @entity8164 -positive @entity1 . No differences in terms of treatment response, recurrences, and final prognosis were observed between both groups of @entity1 .

Clinical features, course and prognosis of XXXX depending on the presence of antibodies against M-type phospholipase A2 receptor.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['membranous nephropathy', 'idiopathic membranous nephropathy'] @entity740 :: ('MESH:D051436', 'Disease') :: ['chronic renal insufficiency'] @entity8164 :: ('22925', 'Gene') :: ['PLA2R'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmune diseases']
@entity8 :: (MESH:D007674,Disease) :: ['idiopathic membranous nephropathy']
