BACKGROUND: Early and midterm results of the arterial switch operation (ASO) in @entity3886 ( @entity3886 ) are good, but late outcome data in large populations are still few. METHODS AND RESULTS: Twelve hundred @entity1 had an ASO for @entity3886 between 1982 and 1999, with prospective follow-up of 1095 survivors. Outcome measures included late @entity204 , reoperation, @entity337 ( @entity337 ), @entity849 ( @entity849 ), and @entity301 . Median follow-up was 4.9 years (range 0.5 to 17 years). Late @entity204 occurred in 32 @entity1 ; survival was 88% at both 10 and 15 years. The hazard function for @entity204 declined rapidly, with no deaths after 5 years. Late mortality was correlated with reintervention and major events in the intensive care unit. Reoperation was performed in 103 @entity1 , more often in complex @entity3886 ; the cause was mainly @entity849 . Freedom from reintervention was 82% at 10 and 15 years, with a hazard function that declined rapidly but slowly increased after 3 years. At the last follow-up, @entity849 was present in 3.9% of @entity1 , and grade II or more @entity337 was present in 3.2%, with a cumulative incidence of 9% at 15 years. Among the 278 @entity1 who had a coronary arteriography, 8% had coronary lesions. @entity11705 were seen in 96.4% and 98.1%, respectively. CONCLUSIONS: Fifteen years after ASO, late mortality was low, with no deaths after 5 years; reoperation, mainly owing to @entity849 , occurred throughout the follow-up. @entity337 and coronary obstruction are rare but warrant further follow-up. Good left ventricular function and sinus rhythm are maintained.

Late outcome after arterial switch operation for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity11705 :: ('MESH:C563907', 'Disease') :: ['Normal left ventricle and sinus rhythm'] @entity301 :: ('MESH:D003327', 'Disease') :: ['coronary anomaly'] @entity3886 :: ('MESH:D014188', 'Disease') :: ['transposition of the great arteries', 'TGA'] @entity849 :: ('MESH:D011666', 'Disease') :: ['pulmonary stenosis', 'PS'] @entity337 :: ('MESH:D001022', 'Disease') :: ['AI', 'aortic insufficiency'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity3886 :: (MESH:D014188,Disease) :: ['transposition of the great arteries']
