OBJECTIVE: The objective of this study was to compare 2-hour postprandial @entity413 measurements with the standard 1-hour, 50 gm glucola screen as a predictor of gestational @entity6 . STUDY DESIGN: In this prospective study, 448 @entity1 were screened for @entity6 after 20 weeks' gestation. Each @entity1 was instructed to ingest a meal containing at least 100 gm of @entity1735 , and 2 hours later a plasma @entity413 level was obtained. Shortly after, each @entity1 was given 50 gm glucola followed by a 1-hour @entity413 measurement. If either screen showed a result of 140 mg/dl or more, a formal 3-hour @entity413 tolerance test was done. Data were analyzed with use of the receiver operating characteristic curve. RESULTS: Of the 448 @entity1 screened, 39 (8.7%) had a screening result of 140 mg/dl or greater and 16 (3.6%) of these had @entity6 . The receiver operating characteristic curve showed that the 1-hour @entity413 screen was more predictive of gestational @entity6 than the postmeal assessment. The area under the receiver operating characteristic curve (plus or minus the SEM) for the 1-hour @entity413 test was 0.746 +/- 0.086 (p < 0.005) whereas the 2-hour postprandial test produced an area of 0.524 +/- 0.097 (p = NS). The range of optimal 1-hour glucola discriminatory values was 182 to 190 mg/dl. Thus the critical cutoff value of the 1-hour glucola test that minimizes false-positive results and maximizes true-positive screening for gestational @entity6 is 182 mg/dl or greater. CONCLUSIONS: The 1-hour glucola test is a reliable screening test for @entity6 whereas the 2-hour post-prandial test is not.

Two-hour postprandial test versus one-hour, fifty-gram glucola test as screening tools for gestational XXXX : a critical analysis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1735 :: ('CHEBI:16646', 'Chemical') :: ['carbohydrate'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity6 :: ('MESH:D003920', 'Disease') :: ['gestational diabetes mellitus', 'diabetes']
@entity6 :: (MESH:D003920,Disease) :: ['diabetes']
