OBJECTIVE: To evaluate the effect of stochastic resonance (SR) stimulation on preterm @entity1 @entity26 desaturation, @entity1168 , and @entity386 events. We hypothesized that SR stimulation will reduce these events. METHODS: This was a randomized crossover study conducted from April 2012 to July 2014. Eligible preterm @entity1 were not receiving ventilation support and had at least 1 clinically documented @entity386 , @entity1168 , and/or @entity26 desaturation event. The 3 outcome variables were as follows: @entity26 desaturation, @entity1168 , and @entity386 events. @entity1 received up to two 3- or 4-hour intervention periods of 30-minute alternating intervals of SR stimulation and no SR stimulation. The first intervention period was randomly assigned to begin with SR stimulation either on or off, whereas the next intervention period automatically began with the opposite on/off state. We compared the SR stimulation "on" periods with the SR stimulation "off" periods with each @entity1 serving as his or her own control. RESULTS: The sample consisted of 36 @entity1 with a mean (  SD) gestational age of 30.5    3 weeks and a birth weight of 1409    450 g. SR stimulation decreased the number of apneic events by 50%. SR stimulation ameliorated every aspect of clinically significant @entity26 desaturation events, with a 20% to 35% decrease in the number, duration, and intensity of @entity26 desaturation events when SR stimulation was on. Also, SR stimulation produced a nearly 20% reduction in the intensity of @entity1168 events. CONCLUSIONS: SR stimulation may be a noninvasive and nonpharmacologic treatment option for @entity386 , @entity26 desaturation, and some aspects of @entity1168 in premature @entity1 .

Stochastic Resonance Effects on @entity386 , XXXX , and Oxygenation: A Randomized Controlled Trial.

@entity1 :: ('9606', 'Species') :: ['infants', 'Infants', 'infant'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['bradycardia'] @entity386 :: ('MESH:D001049', 'Disease') :: ['apnea']
@entity1168 :: (MESH:D001919,Disease) :: ['Bradycardia']
