PURPOSE: To compare the intellectual and language functions of @entity1 of mothers with @entity302 (CME) with that of controls matched for age and socioeconomic status. METHODS: Cases were CME, aged six years or more (n = 71), drawn from a prospective cohort in the Kerala Registry of @entity302 and Pregnancy. Controls were 201 @entity1 of parents without @entity302 , matched for age and socioeconomic status. The outcome measures included Indian adaptation of Wechsler Intelligence Scale for @entity1 and @entity22757 -a locally developed proficiency test for regional language. All relevant data were abstracted from the registry records. RESULTS: The Full Scale IQ and @entity22757 scores were significantly lower for the cases (87.7 +/- 22.6 and 73.4 +/- 17.3) compared to controls (93.0 +/- 14.4 and 83.2 +/- 11.8). Compared to controls, CME scored poor on all subtests of @entity22757 but their impairment was confined to only some of the subtests of IQ. Maternal education and maternal IQ significantly correlated with @entity258 and @entity22757 scores for CME whereas type of @entity302 , @entity410 during pregnancy or low birth weight did not have any significant association with these outcome measures. Polytherapy and higher dosage of antiepileptic drugs (AEDs) were associated with significant impairment in outcome measures. @entity1 with low developmental quotient at one year of age continued to have low scores on outcome measures at six years. CONCLUSIONS: Low maternal IQ, maternal education, and antenatal AED exposure were associated with significant impairment of intellectual and language functions for CME at six years.

Intellectual and language functions in XXXX of mothers with @entity302 .

@entity1 :: ('9606', 'Species') :: ['children', 'Infants'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity22757 :: ('51776', 'Gene') :: ['MLT'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy', 'Epilepsy'] @entity258 :: ('MESH:D009800', 'Disease') :: ['low IQ']
@entity1 :: (9606,Species) :: ['children']
