OBJECTIVE: To study the changes of the clinical aspects of @entity96 ( @entity96 ) during the past 30 years. METHODS: The clinical data of 3,250 @entity1 with @entity96 , from 10 regions of China were collected, analyzed, and compared with the clinical data of 3254 @entity96 cases 30 years before. RESULTS: The 3,250 @entity1 were aged 1- 80, with an average age of 49.1 years, younger than those 30 years before (43.7 years). The male to female ratio was 2.3:1, lower than that 30 years before (7.7:1). 73.5% of them sought medical advice within 3 months after the onset in comparison of 63.8% 30 years before. Compared with those 30 years before the symptoms and signs were alleviated in general. The HBsAg positive rate was 81.0%, the @entity3531 -Ag positive rate was 13.2%, and the alpha-fetoprotein positive rate was 75%. 1912 cases underwent pathological examination of which 91.8% were diagnosed as with @entity157 . The overall resection rate was 46,3%. Those of early, median, and late stages accounted for 29.9%, 51.5%, and 18.6% respectively in comparison with the rates of 0.4%, 47.0%, and 52.6% 30 years before. The one-year survival rate, three-year survival rate, and five-year survival rate were 66.1%, 39.7%, and 32.5% respectively for the whole group, 93.5%, 70.1%, and 59.1% for the early stage @entity1 , and 65.3%, 30.5%, and 23.5% respectively for the median stage @entity1 . The half-year survival rate and one-year survival rate of the late stage @entity1 were 52.5% and 14.7% respectively. Compared with the data 30 years before a lower percentages of the @entity1 died of @entity5693 , @entity548 of upper digestive tract and @entity548 due to @entity5 , and a higher percentage of then died of asthenia universalis and other causes. CONCLUSION: In comparison with the situation 30 years ago, @entity96 can be diagnosed earlier. More @entity1 undergo resection. The prognosis of @entity96 has been improved greatly.

[Changes of clinical aspect of XXXX in China during the past 30 years--control study for 3,250 cases with @entity96 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5693 :: ('MESH:D006501', 'Disease') :: ['hepatic coma'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity3531 :: ('11096', 'Species') :: ['HCV'] @entity96 :: ('MESH:D008113', 'Disease') :: ['PLC', 'primary liver cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['rupture of tumor'] @entity157 :: ('MESH:D006528', 'Disease') :: ['hepatocellular carcinoma']
@entity96 :: (MESH:D008113,Disease) :: ['primary liver cancer']
