BACKGROUND: Complete mesocolic excision (CME) seems to be associated with improved oncological outcomes compared with 'conventional' surgery, but there is a potential for higher morbidity. METHODS: Data for @entity1 after elective resection at the four centres in the Capital Region of Denmark (June 2008 to December 2013) were retrieved from the Danish @entity14 Group database and medical charts. Approval from a Danish ethics committee was not required (retrospective study). RESULTS: Some 529 @entity1 who underwent CME surgery at one centre were compared with 1701 @entity1 undergoing 'conventional' resection at the other three hospitals. Laparoscopic CME was performed in 258 (48  8 per cent) and laparoscopic 'conventional' resection in 1172 (68  9 per cent). More extended right colectomy procedures were done in the CME group (17  4 versus 3  6 per cent). The 90-day mortality rate in the CME group was 6  2 per cent versus 4  9 per cent in the 'conventional' group (P   =   0  219), with a propensity score-adjusted logistic regression odds ratio (OR) of 1  22 (95 per cent c.i. 0  79 to 1  87). Laparoscopic surgery was associated with a lower risk of mortality at 90   days (OR 0  63, 0  42 to 0  95). @entity3816 to other organs was more common in CME operations (9  1 per cent versus 3  6 per cent for 'conventional' resection; P   <   0  001), including more @entity4558 (3  2 versus 1  2 per cent; P   =   0  004) and superior mesenteric vein (1  7 versus 0  2 per cent; P   <   0  001) injuries. Rates of @entity295 with vasopressor requirement (6  6 versus 3  2 per cent; P   =   0  001) and @entity1576 (8  1 versus 3  4 per cent; P   <   0  001) were higher in the CME group. CONCLUSION: CME is associated with more intraoperative organ injuries and severe @entity532 than 'conventional' resection for @entity694 .

Short-term outcomes after complete mesocolic excision compared with 'conventional' XXXX surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity532 :: ('MESH:D003925', 'Disease') :: ['non-surgical complications'] @entity4558 :: ('MESH:D013158', 'Disease') :: ['splenic'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['postoperative respiratory failure'] @entity14 :: ('MESH:D015179', 'Disease') :: ['Colorectal Cancer'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colonic cancer'] @entity3816 :: ('MESH:D007431', 'Disease') :: ['Intraoperative injury']
@entity694 :: (MESH:D003110,Disease) :: ['colonic cancer']
