BACKGROUND AND AIMS:     The diagnostic use of magnification endoscopy with narrow-band imaging (ME-NBI) to assess histopathologically undifferentiated-type early @entity356 (UD-type EGCs) is not well elucidated. The purpose of this study was to examine the comparative relationship between ME-NBI images and histopathological findings in UD-type EGCs. METHODS:     We analyzed 78 consecutive cases of UD-type EGCs    <=   20   mm in diameter that underwent ME-NBI    <=   2   weeks prior to resection. The ME-NBI images were compared with histopathological findings following either @entity5848 ( @entity5848 ) or surgery. Applying the comparative results, we prospectively evaluated the success of identifying the lateral extent of UD-type EGCs resected by @entity5848 in additional consecutive cases. RESULTS:     Lesions with preserved but irregular surface microstructures (S-type based on ME-NBI) showed @entity194 and corresponded histologically to the non-whole-layer type of @entity5 (24/24, 100%). Lesions with an irregular microvasculature type (V-type, for example, corkscrew pattern) or mixed type upon ME-NBI corresponded histopathologically to the non-whole-layer type of @entity5 (15/54, 27.8%), the whole-layer type of @entity5 (27/54, 50.0%) or submucosal (sm) invasion @entity5 (12/54, 22.2%). Applying these comparative results, we used ME-NBI to successfully predict the lateral extent of @entity5 , which corresponded to the histopathological lateral extent in all 18 additional consecutive UD-type EGCs resected by @entity5848 . CONCLUSIONS:     ME-NBI images of UD-type EGCs were very closely related to the histopathological findings. Thus, ME-NBI can be useful in the pretreatment assessment of the histopathological patterns of @entity5 development and the lateral extent of such lesions.

Diagnosis of undifferentiated type early XXXX by magnification endoscopy with narrow-band imaging.

@entity5 :: ('MESH:D009369', 'Disease') :: ['intramucosal cancer', 'cancer'] @entity5848 :: ('MESH:D000784', 'Disease') :: ['ESD', 'endoscopic submucosal dissection'] @entity194 :: ('MESH:D001284', 'Disease') :: ['mucosal atrophy'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancers']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancers']
