BACKGROUND, AIMS: Oral @entity597 -reducing bacteria are involved in several clinical categories of @entity2521 . The aim of this cross-sectional study was to compare the presence of @entity597 -reducing bacteria (SRB) with other putative pathogens including spirochetes, @entity3841 , @entity3289 , @entity2523 , and @entity14148 in periodontal lesions. METHOD: Periodontal SRB were detected by enrichment culture and compared with a microscopic spirochete count (n=168). Species-specific oligonucleotide probes directed against the 16S rRNA were employed to determine the presence of A. actinomycetemcomitans, @entity2523 , @entity3289 , and @entity14148 (n=55). RESULTS: A significant positive correlation was observed between the presence of SRB and the proportions of spirochetes in @entity527 , although the 2 bacterial groups also occurred separately. SRB tended to be negatively correlated with the presence of A. actinomycetemcomitans. In contrast, all pockets with SRB harbored either @entity14148 , or both @entity14148 and @entity3289 (12/14) before therapy. Interestingly, the combination of SRB with @entity2523 occurred in 32% of the periodontal pockets before treatment. After initial periodontal therapy, the prevalence of this combination was reduced to 2% of the sites, and to 25% of the sites in recall @entity1 . CONCLUSION: The presence of SRB was positively correlated with @entity14148 , @entity3289 , and @entity2523 in periodontal lesions. These suspected pathogens form a complex strongly associated with destructive @entity2521 .

XXXX -reducing bacteria in relation with other potential periodontal pathogens.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity527 :: ('MESH:D058225', 'Disease') :: ['subgingival plaque'] @entity14148 :: ('158', 'Species') :: ['T. denticola', 'Treponema denticola'] @entity597 :: ('CHEBI:16189', 'Chemical') :: ['sulfate'] @entity3289 :: ('28112', 'Species') :: ['B. forsythus', 'Bacteroides forsythus'] @entity3841 :: ('714', 'Species') :: ['Actinobacillus actinomycetemcomitans'] @entity2521 :: ('MESH:D010518', 'Disease') :: ['periodontitis'] @entity2523 :: ('837', 'Species') :: ['Porphyromonas gingivalis', 'P. gingivalis']
@entity597 :: (CHEBI:16189,Chemical) :: ['Sulfate']
