BACKGROUND: @entity298 ( @entity298 ) is used as an alternative to hemodialysis in @entity454 ( @entity454 ). Icodextrin has been used as a hyperosmotic agent in @entity298 . The aim of the study was to assess two different point-of-care testing (POCT) @entity413 strips, affected and not affected by icodextrin, with serum @entity413 concentrations of the @entity1 using and not using icodextrin. METHODS: Fifty-two chronic ambulatory peritoneal dialysis (CAPD) @entity1 using icodextrin (Extraneal  ) and 20 CAPD @entity1 using another hyperosmotic fluid (Dianeal  ) were included in the study. Duplicate capillary and serum @entity413 concentrations were measured with two different POCT @entity413 strips and central laboratory hexokinase method. Assay principles of @entity413 strips were based on @entity413 dehydrogenase- @entity31937 ( @entity57685 -PQQ) and a mutant variant of @entity57685 (Mut @entity57685 ). The results of both strips were compared with those of hexokinase method. RESULTS: Regression equations between POCT and hexokinase methods in icodextrin group were y = 2.55x + 1.12 mmol/l and y = 1.057x + 0.16 mmol/l for the @entity57685 -PQQ and Mut @entity57685 methods, respectively. The mean difference between the results of hexokinase and those of @entity57685 -PQQ and Mut @entity57685 in icodextrin group was 3.41    1.56 and 0.72    0.64 mmol/l, respectively. However, the mean differences were found much lower in the control group; 0.64 mmol/l for @entity57685 -PQQ and 0.52 mmol/l for Mut @entity57685 . CONCLUSION: Compared to @entity57685 - @entity31938 , @entity413 strips of Mut @entity57685 correlated better with hexokinase method in @entity298 @entity1 using icodextrin.

Falsely Elevated @entity413 Concentrations in Peritoneal Dialysis XXXX Using Icodextrin.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal disease', 'ESRD'] @entity298 :: ('MESH:D010538', 'Disease') :: ['Peritoneal dialysis', 'PD'] @entity57685 :: ('9563', 'Gene') :: ['Q-GDH', 'GDH'] @entity31938 :: ('CHEBI:18315', 'Chemical') :: ['PQQ'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity31937 :: ('MESH:D045542', 'Chemical') :: ['pyrroloquinoline quinone']
@entity1 :: (9606,Species) :: ['Patients']
