BACKGROUND: @entity401 ( @entity401 ) is characterized by interstitial infiltration of T lymphocytes, and subpopulations of these cells may be associated with the progression of @entity82 . However, few studies evaluate the correlation of prognosis with this characteristic. Therefore, we performed morphological and quantitative analyses of T lymphocytes in @entity1 with @entity401 and evaluated the relationship between T lymphocytes and prognosis. METHODS: Immunohistochemistry was used to detect the presence of @entity404 + and @entity405 + T lymphocytes in 55 biopsies of @entity1 with @entity401 to determine the numbers of these T cell subpopulations in lymphoid follicles as well as in perivascular, interstitial, and peribronchial anatomical compartments. The relationship between @entity404 + and @entity405 + T lymphocyte populations and prognosis was analyzed. RESULTS: The mean age of 55 @entity1 was 48.9        10.5  years, and 36 (65  %) of @entity1 were @entity1 . All @entity1 were followed for a mean duration of 46        25  months. Thirteen (23.6  %) @entity1 died during follow-up. Perivascular @entity404 + lymphocyte infiltration (HR, 0.939; 95  % CI, 0.883-0.999; p   =   0.048) was an independent risk factor for survival. Perivascular infiltrates of @entity404 + T lymphocytes correlated with survival time (r   =   0.270, p   =   0.046). @entity1 with improved forced vital capacity survived longer and had higher numbers of @entity404 + T lymphocytes that infiltrated perivascular tissue. The densities of @entity404 + and @entity405 + T lymphocytes infiltrating other tissues were not significantly associated with survival time. CONCLUSIONS: Perivascular infiltration of @entity404 + T lymphocytes in @entity1 with @entity401 correlated with prognosis. The underlying mechanisms are unknown and require further studies.

Prognosis of nonspecific XXXX correlates with perivascular @entity404 + T lymphocyte infiltration of the lung.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity404 :: ('920', 'Gene') :: ['CD4'] @entity401 :: ('MESH:D017563', 'Disease') :: ['NSIP', 'Nonspecific interstitial pneumonia'] @entity405 :: ('925', 'Gene') :: ['CD8']
@entity401 :: (MESH:D017563,Disease) :: ['interstitial pneumonia']
