BACKGROUND: Aspiration events (AEs) are a well-recognized complication in @entity130 @entity1 and have traditionally been considered a risk factor for @entity55 . Despite this, there is no consensus on the incidence or clinical significance of AE in the @entity130 population. METHODS: All @entity1 admitted as @entity130 team activations at our Level I @entity130 center who were intubated in the field or on arrival from September 2013 to August 2014 were prospectively collected. Field and admission data including witnessed AEs were analyzed. Additional hospital data included imaging, associated injuries, laboratory, and clinical data. Early @entity1576 , @entity55 , and hospital mortality were collected. RESULTS: During the study period, 228 @entity1 met inclusion criteria. Median age was 35.5 years, and Injury Severity Score (ISS) was 21.0. Overall, 58 @entity1 (25.4%) had witnessed AEs. @entity1 with AE had significantly higher ISS (26.0 vs. 17.0, p = 0.027) and lower Glasgow @entity772 Scale (GCS) score on admission (median, 4.0 vs. 7.0; p = 0.003), despite similar field GCS score (p = 0.946). Body mass index (median, 27.2 vs. 26.2; p = 0.374) and intoxication rates (86.2% vs. 83.5%, p = 0.835) were similar between groups. Early @entity55 and @entity1576 were rare in all @entity1 and were not higher in those with AE. Although mortality was higher after AE in @entity1 who died directly after admission (51.7% vs. 30.0%, p = 0.004), in @entity1 who survived to intensive care unit admission, there was no longer a difference between groups and aspiration was not an independent predictor of mortality (p = 0.107) on multivariable regression analysis. CONCLUSION: The rate of aspiration in @entity130 is high and more likely to occur in @entity1 with @entity308 GCS score. In @entity1 who survive past admission, early @entity55 rates are similar, regardless of AE. These data suggest that aspiration is a marker of severe @entity221 and is associated with but not an independent predictor of mortality. LEVEL OF EVIDENCE: Prognostic/epidemiologic study, level III.

Witnessed aspiration in XXXX : Frequent occurrence, rare morbidity-A prospective analysis.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['increased injury burden or depressed'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity772 :: ('MESH:D003128', 'Disease') :: ['Coma'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory failure'] @entity221 :: ('MESH:D005334', 'Disease') :: ['illness'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity130 :: (MESH:D014947,Disease) :: ['trauma']
