OBJECTIVE: To establish the safety and efficacy of endovascular repair of @entity2334 . METHODS: Between May 2004 and February 2006, @entity1 with @entity439 considered high risk for conventional surgery were enrolled in a prospective trial to evaluate a novel endovascular grafting system. Devices were custom designed for each @entity1 using high-resolution computed tomography. @entity1 data included mortality, morbidity, procedural details, and surrogate end points for endovascular repair. These were collected at hospital discharge and at 1, 6, and 12 months. RESULTS: Seventy-three @entity1 underwent endovascular repair of @entity2334 , II, or III (n = 28), or for type IV (n = 45) @entity439 . Mean @entity439 size was 7.1 cm (range 4.5-11.3 cm). General anesthesia was used in 47% of @entity1 and regional anesthesia in 53%. There were no conversions to open surgery nor ruptures post-treatment. Technical success was achieved in 93% of @entity1 (68/73). Thirty-day mortality was 5.5% (4/73). Major perioperative complications occurred in 11 (14%) @entity1 and included @entity451 (2.7%, 2/73), new onset of dialysis (1.4%, 1/73), prolonged ventilator support (6.8%, 5/73), @entity583 (5.5%, 4/73), and minor @entity64 (1.4%; 1/72). A majority of @entity1 had no complications. Mean length of stay was 8.6 days. At follow-up, 6 deaths had occurred. There were no instances of stent migration nor aneurysmal growth. CONCLUSIONS: Endovascular repair of aortic @entity439 involving the visceral segment in nonsurgical candidates is feasible. Known complications of repair are not eliminated, but morbidity and mortality appeared low relative to the high-risk population studied. Further refinement of device design, delivery technique, and @entity1 selection is ongoing. Assessment of durability will require longer follow-up.

Endovascular treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['hemorrhagic stroke'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity2334 :: ('MESH:D017545', 'Disease') :: ['thoracoabdominal aortic aneurysms for type I', 'thoracoabdominal aortic aneurysms'] @entity439 :: ('MESH:D000783', 'Disease') :: ['thoracoabdominal aneurysms', 'aneurysms', 'aneurysm'] @entity451 :: ('MESH:C536857', 'Disease') :: ['paraplegia']
@entity2334 :: (MESH:D017545,Disease) :: ['thoracoabdominal aortic aneurysms']
