PURPOSE: To assess reproducibility in measuring left ventricular (LV) @entity296 in volunteers throughout the cardiac cycle using MR elastography (MRE) and to determine its correlation with age. METHODS: Cardiac MRE (CMRE) was performed on 29 normal volunteers, with ages ranging from 21 to 73 years. For assessing reproducibility of CMRE-derived stiffness measurements, scans were repeated per volunteer. Wave images were acquired throughout the LV myocardium, and were analyzed to obtain mean stiffness during the cardiac cycle. CMRE-derived stiffness values were correlated to age. RESULTS: Concordance correlation coefficient revealed good interscan agreement with rc of 0.77, with P-value   <   0.0001. Significantly higher @entity296 was observed during end-systole (ES) compared with @entity998 ( @entity998 ) across all subjects. Additionally, increased deviation between ES and @entity998 stiffness was observed with increased age. CONCLUSION: CMRE-derived stiffness is reproducible, with @entity296 changing cyclically across the cardiac cycle. Stiffness is significantly higher during ES compared with @entity998 . With age, ES @entity296 increases more than @entity998 , giving rise to an increased deviation between the two. Magn Reson Med 75:1586-1593, 2016.    2015 Wiley Periodicals, Inc.

Measuring age-dependent XXXX across the cardiac cycle using MR elastography: A reproducibility study.

@entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial stiffness'] @entity998 :: ('MESH:D002303', 'Disease') :: ['ED', 'end-diastole']
@entity296 :: (MESH:D009202,Disease) :: ['myocardial stiffness']
