BACKGROUND: The clinical course of unilesional plaques with a histological diagnosis of @entity3217 fungoides is generally benign. This uncommon situation raises the question of nosology among epidermotropic T-cell proliferations. CASE REPORT: Two @entity1 (age 65 and 70 years, cases 1 and 2) and one @entity1 (age 66 years, case 3) each had a well-limited unique oval-shaped plaque measuring 1 to 3 cm in diameter for several months. The localization of the erythematous, squamous plaques with minimal infiltration and little or no pruritus remained unchanged in the dorsal area. Histology reported @entity3217 fungoides: dense superficial dermal infiltration in band attached to the epidermis with a clear lower limit, formed by small and medium-sized atypical lymphocytes, sometimes with cerebriform nuclei. Epidermotropism on isolated cells or theques was noted. There was no spongiosis. Immunolabeling demonstrated predominance of @entity404 + cells and tumoral infiltration uptake of anti-V beta 8 monoclonal antibodies in the two cases examined. The lesion totally regressed in case 1 after local application of @entity3600 with no recurrence after 5 years. @entity1 2 declined treatment and no change was observed 5 years later. Surgical exeresis was performed in case 3 without recurrence 3 years later. DISCUSSION: No histological feature or T-cell immunophenotype distinguishes this clinical entity from @entity4888 . As no other long-term lesions developed, our three cases would argue for a benign course of what is probably a variety of @entity3217 fungoides. Unilesional @entity4888 must be @entity5526 . @entity33835 differs by its nearly exclusive epidermotropic distribution.

[Unilesional plaque-type XXXX fungoides: 3 cases].

@entity1 :: ('9606', 'Species') :: ['women', 'Patient', 'man'] @entity4888 :: ('MESH:D009182', 'Disease') :: ['classical mycosis fungoides', 'plaque mycosis fungoides'] @entity404 :: ('920', 'Gene') :: ['CD4'] @entity3217 :: ('MESH:D015821', 'Disease') :: ['mycosis'] @entity33835 :: ('MESH:D056267', 'Disease') :: ['Woringer-Kolopp disease'] @entity5526 :: ('MESH:D003877', 'Disease') :: ['lymphomatoid contact dermatitis'] @entity3600 :: ('MESH:D002330', 'Chemical') :: ['carmustine']
@entity3217 :: (MESH:D015821,Disease) :: ['mycosis']
