PURPOSE: Endovascular mechanical thrombectomy (mTE) in acute @entity385 due to large cerebral @entity432 is effective and safe. The procedure is currently offered by specialized hospitals. Physicians from smaller hospitals need to refer @entity1 to @entity64 centers. Secondary referrals involve delays for transportation. Little is known about effects of distant referrals on outcome and complications as compared to direct admittance. METHODS: To evaluate the effects of referral patterns on outcome and safety, we analyzed 941 @entity1 with anterior circulation @entity64 receiving mTE between January 2010 and December 2015. @entity1 were divided into three groups: directly admitted @entity1 (DAP), @entity389 ( @entity389 ) and long-distance referrals (LDR). We assessed (1)  procedural parameters (2)  frequency of good functional outcome (mRS <= 2 at 3  months) and (3)  mortality rates. RESULTS: Referrals had a significantly longer imaging-to-groin time compared to DAP (median 150  min vs. 85  min, p  <0.001), the same was true for LDR vs. @entity389 (median 157  min vs. 133.5  min, p  <0.001). Time to recanalization was significantly longer for referrals compared to DAP (median 348  min vs. 260  min, p  <0.001). There was no significant difference in the frequency of good functional outcome (DAP 39.5%, @entity389 35.1%, LDR 37.0%; p  =0.709), all-cause mortality at day 90 (DAP 31.5%, @entity389 23.0%, LDR 27.0%; p  =0.212) and the rate of symptomatic @entity932 (p  =0.834). CONCLUSION: Timing remains a critical factor in acute @entity385 treatment by endovascular means. Long distance referral to specialized @entity531 with high recanalization rates, however, does allow for a good functional outcome in a significant number of @entity1 .

Endovascular Thrombectomy in Acute XXXX : Outcome in Referred Versus Directly Admitted @entity1 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity932 :: ('MESH:D020300', 'Disease') :: ['intracranial hemorrhage'] @entity389 :: ('MESH:D007759', 'Disease') :: ['ICT', 'inner-city transfers'] @entity432 :: ('MESH:D001157', 'Disease') :: ['artery occlusion'] @entity531 :: ('MESH:D013901', 'Disease') :: ['neurovascular centers'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['Ischemic Stroke']
