Our purpose was to analyze detection, diagnostic characterization, and staging of renal solid lesions using different fast T1-weighted sequences with fat suppression in breath-hold mode compared with a gradient-echo sequence after contrast application. Twenty-five @entity1 with focal @entity8 were examined with a T1-weighted ultrafast turbo spin-echo (UTSE) sequence with frequency selective fat suppression (SPIR), two different segmented echo-planar imaging (EPI) sequences - a spin-echo and a gradient-echo echo-planar sequence (SE-, FFE-EPI) combined with SPIR and a gradient-echo (fast field echo, FFE) sequence in a prospective study. The images of all sequences were visually evaluated and in addition to qualitative evaluation the contrast-to-noise ratio (CNR) for cyst and solid lesions was measured. Among the different T1-weighted sequences, the best detection and characterization of renal solid lesions were obtained with the UTSE SPIR and the SE-EPI sequence (sensitivity: 100 and 75%, respectively; specificity: 90 and 75%, respectively). The FFE and FFE-EPI sequences showed lower sensitivity (86%) and the same specificity (75%). The staging of @entity703 was best achieved with the UTSE SPIR and SE-EPI sequence (84 and 73%, respectively). The staging was correct in only 47% and 58 for the FFE and FFE-EPI sequences, respectively. The investigated sequences showed no significant differences in CNR. The combination of fat suppression and breath-hold mode improves detection, characterization, and staging of @entity8 . The UTSE SPIR and SE-EPI sequence in breath-hold mode showed specific image artifacts, but offered high sensitivity and specificity for detection and characterization of @entity8 compared with the FFE sequence. The results of this study suggest, for T1-weighted imaging of @entity703 , use of UTSE or SE-EPI sequences with fat suppression in breath-hold mode for renal imaging.

Fast sequences with fat suppression in breath-hold mode: new standard in contrast-enhanced T1-weighted MR imaging of XXXX ?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal lesions'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal tumors']
@entity703 :: (MESH:D007680,Disease) :: ['renal tumors']
