BACKGROUND/AIMS: The effect of lymph node @entity3 around the splenic artery on the prognosis of proximal @entity356 @entity1 is not confirmed. The aim of this study is to clarify the optimal procedure for lymph node dissection along the splenic artery in proximal @entity356 . METHODOLOGY: Proximal @entity356 @entity1 who underwent total gastrectomy with pancreaticosplenectomy were examined. The anatomical location of lymph nodes and the @entity3 around the pancreas were also studied in @entity788 @entity1 who underwent total pancreatectomy. RESULTS: Multivariate analysis of lymph node @entity3 around the splenic artery showed that No. 11 lymph node @entity3 was affected by No.10 lymph node that was predicted by depth of invasion. Multivariate analysis of prognostic variables by Cox's proportional hazard regression revealed that No. 10 lymph node @entity3 was the significant factor affecting prognosis. No lymph node @entity3 infiltrating the pancreatic parenchyma was observed in the pancreatic body or the tail. CONCLUSIONS: Total gastrectomy preserving the pancreas and spleen is the optimal procedure in proximal T2 @entity356 . Total gastrectomy with splenectomy is appropriate in T3 cases, and distal pancreatectomy should be additionally done only in cases of direct invasion by the lymph node and/or the @entity5 to the pancreas.

Procedure for lymph node dissection around splenic artery in proximal XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis', 'metastases'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer']
@entity356 :: (MESH:D013274,Disease) :: ['gastric cancer']
