The purpose of this study was to review the published evidence of the effects of @entity85 , and their implications on the quality of life of these @entity1 . With increasing longevity of @entity1577 @entity1 , musculoskeletal manifestations have become important. Decreased @entity79 ( @entity79 ) and bone mineral content (BMC) are common at all ages in @entity1577 @entity1 , and its cause is probably multifactorial. Risk factors contributing to decreased BMC include age of the @entity1 , imbalance between bone accretion and degradation, body mass, nutrition, activity, exposure to glucocorticoid therapy, and @entity10844 . BMC correlates strongly to fat-free mass in @entity1577 @entity1 . Lung transplant, while increasing life span, can worsen @entity170 . Twenty-nine percent of @entity1 are below the 10th percentile for height. @entity174 rates are approximately twofold greater in females aged 16 to 32 years and males aged 25 to 34 years. Female @entity1 aged 6 to 16 have a higher than normal fracture rate and a higher rate than their male counterparts. Spinal consequences of @entity170 include @entity1513 in up to 62% of @entity1 . Back @entity158 was noted in 94% of @entity1 . @entity625 in @entity1577 , although less common, can be very incapacitating, and it is mainly of three types: @entity625 , @entity3582 , and @entity625 due to co-existent conditions and drug reactions. The treatment of @entity625 is mainly symptomatic in the majority of cases.

Musculoskeletal involvement in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity10844 :: ('MESH:D006058', 'Disease') :: ['gonadal dysfunction'] @entity625 :: ('MESH:D001168', 'Disease') :: ['CF arthritis', 'arthritis', 'Arthritis'] @entity174 :: ('MESH:D050723', 'Disease') :: ['Fracture'] @entity1513 :: ('MESH:D007738', 'Disease') :: ['excessive kyphosis'] @entity170 :: ('MESH:D010024', 'Disease') :: ['osteoporosis'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity85 :: ('MESH:D009140', 'Disease') :: ['cystic fibrosis (CF) on the musculoskeletal system'] @entity1577 :: ('MESH:D003550', 'Disease') :: ['CF'] @entity3582 :: ('MESH:D010004', 'Disease') :: ['hypertrophic osteoarthropathy']
@entity1577 :: (MESH:D003550,Disease) :: ['cystic fibrosis']
