OBJECTIVE: There is growing evidence that cerebellum plays a crucial role in cognition and emotional regulation. Cerebellum is likely to be involved in the physiopathology of both @entity162 and @entity161 . The objective of our study was to compare cerebellar size between @entity1 with @entity162 , @entity1 with @entity161 , and healthy controls in a multicenter sample. In addition, we studied the influence of @entity716 features on cerebellar size in @entity1 with @entity162 . METHOD: One hundred and fifteen @entity1 with @entity162 , 32 @entity1 with @entity161 , and 52 healthy controls underwent 3  Tesla MRI. Automated segmentation of cerebellum was performed using FreeSurfer software. Volumes of cerebellar cortex and white matter were extracted. Analyses of covariance were conducted, and age, sex, and intracranial volume were considered as covariates. RESULTS: Bilateral cerebellar cortical volumes were smaller in @entity1 with @entity161 compared with @entity1 with @entity162 and healthy controls. We found no significant difference of cerebellar volume between bipolar @entity1 with and without @entity716 features. No change was evidenced in white matter. CONCLUSION: Our results suggest that reduction in cerebellar cortical volume is specific to @entity161 . @entity76 in @entity162 , if present, appears to be more subtle than a reduction in cerebellar volume.

Cerebellar volume in XXXX and @entity162 with and without @entity716 features.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity162 :: ('MESH:D001714', 'Disease') :: ['bipolar disorder', 'bipolar I disorder'] @entity161 :: ('MESH:D012559', 'Disease') :: ['schizophrenia'] @entity76 :: ('MESH:D002526', 'Disease') :: ['Cerebellar dysfunction'] @entity716 :: ('MESH:D011605', 'Disease') :: ['psychotic']
@entity161 :: (MESH:D012559,Disease) :: ['schizophrenia']
