BACKGROUND @entity409 , which can be measured by @entity384 ( @entity384 ), is an early clinical marker of @entity731 , which is considered to be the main cause of the observed @entity65 in @entity27 ( @entity27 ) @entity1 . The association between @entity27 and @entity409 has been reported in a number of studies; however, the findings are not entirely consistent. Our aim was to meta-analytically synthesize the existing evidence to explore the association between @entity27 and @entity409 . MATERIAL AND METHODS Data from PubMed, EMBASE, the Cochrane library, and Google Scholar for all trials that investigated the relationship between @entity409 and @entity27 were systematically reviewed. The minimum inclusion criteria for the studies were reporting of the @entity27 ( @entity27 ) and @entity384 measurements (as an indicator of @entity409 ) for both @entity27 and control groups. Data from case-control studies that met the inclusion criteria were extracted. RESULTS Twenty-eight studies comprising a total of 1496 @entity27 @entity1 and 1135 controls were included in the meta-analysis. A random-effects model was used. The weighted mean difference in the @entity384 measurements was -3.07 and the 95% confidence interval was -3.71 to -2.43 (P<0.01). Meta-regression analysis showed that age, sex, body mass index (BMI), blood pressure, @entity413 , high-density lipoprotein (HDL) @entity165 , and low-density lipoprotein (LDL) @entity165 did not explain the heterogeneity. CONCLUSIONS This meta-analysis showed that @entity1 with @entity27 have decreased @entity384 , which may contribute to the development of @entity731 .

XXXX with Obstructive Sleep Apnea Display @entity384 : Evidence from a Meta-Analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity384 :: ('MESH:D002311', 'Disease') :: ['FMD', 'flow-mediated dilatation'] @entity409 :: ('MESH:D008107', 'Disease') :: ['endothelial dysfunction', 'Endothelial dysfunction'] @entity27 :: ('MESH:D020181', 'Disease') :: ['AHI', 'obstructive sleep apnea', 'Apnea-Hypopnea Index', 'OSA'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular complications'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity1 :: (9606,Species) :: ['Patients']
