OBJECTIVE: To describe the development of the Impact of Migraine on Partners and Adolescent @entity1 (IMPAC) scale. BACKGROUND: Although existing data and clinical experience suggest that the impact of @entity2704 is pervasive and extends beyond the individual with @entity2704 , no validated tools exist for assessing the impact of @entity2704 on the family. METHODS: The Chronic Migraine Epidemiology and Outcomes (CaMEO) Study is a longitudinal study of @entity1 with @entity2704 in the United States. The Family Burden Module (FBM) of the CaMEO Study contained an item pool of 53 questions derived through literature review, clinician input, and @entity1 focus groups pertaining to the following concepts: impact of @entity2704 on family interpersonal relationships, activities, well-being, finances, and health-related quality of life. Respondents with @entity2704 (ie, probands) were categorized into 4 groups based on household composition: @entity2704 probands with partners/spouses and @entity1 (M-PC), @entity2704 probands with partners/spouses only (M-P), @entity2704 probands with @entity1 (ren) only (M-C), and @entity2704 probands without a partner/spouse or @entity1 (ren) (M-O). The IMPAC scale was developed in 3 steps: (1) exploratory factor analysis and item reduction, (2) bifactor analysis, confirmatory factor analysis, and scoring, and (3) reliability and construct validity analyses. RESULTS: The analysis of data from 13,064 respondents to the FBM meeting criteria for @entity2704 yielded a 12-item IMPAC scale, with 4 items applying to all of the groups, 4 more items applying to the groups with partners (M-P and M-PC), and 4 additional items to the groups with @entity1 (M-C and M-PC). Item responses can be summed and converted into a scoring system assessing mild (<0.5 SD below mean; IMPAC scale Grade I), moderate (0.5 SD below to <0.5 SD above mean; Grade II), severe (0.5-<1.5 SD above mean; Grade III), and very severe (>= 0.5 SD above mean; Grade IV) family impact. Test information curves relating to the IMPAC scale for each household type indicated adequate reliability across a large range of family burden severity (from    1 SD below to    3 SD above mean) and IMPAC scores showed moderate-to-large correlations with other validated tools (range,        0.38-0.52), providing support for construct validity. CONCLUSIONS: We developed a questionnaire to assess family burden attributed to @entity2704 that is brief, robust, and psychometrically sound, with a simple scoring algorithm that can be applied to various household compositions. This questionnaire may be valuable in research settings to provide quantifiable data on the impact of @entity2704 on family dynamics and in clinical settings to facilitate conversations about family burden as a target and a motivation for better treatment.

Family Impact of Migraine: Development of the Impact of Migraine on Partners and Adolescent XXXX (IMPAC) Scale.

@entity1 :: ('9606', 'Species') :: ['child', 'children', 'Children', 'patient', 'people'] @entity2704 :: ('MESH:D008881', 'Disease') :: ['migraine']
@entity1 :: (9606,Species) :: ['Children']
