An analysis is presented of 188 @entity1 with a histological diagnosis of @entity4797 testis, treated by radical orchiectomy and radiation therapy between 1960 and 1981 at the @entity5 Institute. Using the Walter Reed Hospital staging classification, 149 (79%) @entity1 were Stage I, 34 (18%) were Stage II, and 5 (3%) were Stage III. The 5-year survival for all stages was 90%, and for Stage I was 98%, Stage II, 71%, and Stage III, 0%. All were treated primarily with radiation therapy. Prophylactic mediastinal radiation was not employed for Stage I, and was employed in half of Stage II @entity1 . Eleven @entity1 with Stage I relapsed, five in the mediastinum and/or neck nodes. Eight of 11 were cured with further treatment. Stage II @entity1 were subdivided according to the presence or absence of a palpable abdominal mass. @entity66 (Stage IIB) carried a poorer prognosis. Three of 20 @entity1 without a palpable mass (Stage IIA) died of disease; there was an 82% five-year survival rate. Eight of 14 with a palpable mass (Stage IIB) were cured by radiotherapy; there was a 54% five-year survival rate. All five Stage III @entity1 died within 1 year of diagnosis. Stage I and IIA @entity4797 is curable by radiation alone. Prophylactic mediastinal radiation is not indicated in either @entity5 . Long term @entity137 from radiation is not seen. Optimal treatment for Stage IIB disease is undetermined and new treatment regimens should be explored. Stage III disease requires primary chemotherapy.

XXXX : a 22-year experience with radiation therapy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity66 :: ('MESH:D004194', 'Disease') :: ['Palpable disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Cross Cancer', 'Stage I or IIA disease'] @entity4797 :: ('MESH:D018239', 'Disease') :: ['seminoma']
@entity4797 :: (MESH:D018239,Disease) :: ['Seminoma of the testis']
