UNASSIGNED: Aerobic exercise training has been shown to attenuate @entity73 and reduce @entity1010 with advancing age. The extent to which resistance exercise training improves cognition and prevents @entity1010 is less known, and few studies include long-term follow-up cognitive and neuroimaging assessments. We report data from a randomized controlled trial of 155 older @entity1 , who engaged in 52 weeks of resistance training (either once- or twice-weekly) or balance-and-toning (twice-weekly). Executive functioning and memory were assessed at baseline, 1-year follow-up (i.e., immediately post-intervention), and 2-year follow-up. A subset underwent structural magnetic resonance imaging scans at those time points. At 2-year follow-up, both frequencies of resistance training promoted executive function compared to balance-and-toning (standardized difference [d]=.31-.48). Additionally, twice-weekly resistance training promoted memory (d=.45), reduced cortical @entity62 (d=.45), and increased peak muscle power (d=.27) at 2-year follow-up relative to balance-and-toning. These effects were independent of one another. These findings suggest resistance training may have a long-term impact on cognition and white matter volume in older @entity1 . (JINS, 2015, 21, 745-756).

Long-Term Effects of Resistance Exercise Training on Cognition and Brain Volume in Older XXXX : Results from a Randomized Controlled Trial.

@entity1 :: ('9606', 'Species') :: ['women'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive decline'] @entity62 :: ('MESH:D056784', 'Disease') :: ['white matter atrophy'] @entity1010 :: ('MESH:C566985', 'Disease') :: ['brain atrophy']
@entity1 :: (9606,Species) :: ['Women']
