In @entity5924 , @entity32 and @entity82 lead to narrowing or occlusion of @entity133 . To determine how bronchiolar structural alterations relate to lung physiology, 19 @entity1 with a pathological diagnosis of @entity5924 were studied. The bronchiolar inflammatory and fibrotic features were correlated to the clinical presentation, and lung function tests. Eleven @entity1 demonstrated airflow limitation, one had a restrictive pattern and one had a mixed pattern, two had isolated gas trapping, but four had normal spirometry. Mild-to-moderate @entity32 was invariably present. It involved 60% of bronchioles subepithelially and 54% in the adventitia. Subepithelial @entity82 was observed in 15 @entity1 and adventitial in 12. @entity32 correlated with forced expiratory volume in one second and forced vital capacity and inversely correlated with residual volume. Subepithelial @entity82 inversely correlated with @entity32 . High-resolution computed tomography in 10 @entity1 revealed inspiratory (five out of 10) and expiratory air trapping (five out of five), ground glass opacities (seven out of 10), bronchial wall thickening (five out of 10), @entity4595 (two out of 10) and centrilobular nodules (two out of 10). The present study suggests that @entity32 and @entity82 occurs in bronchioles at different time points in the disease process, or that there is no transition between these types of pathology in the same @entity1 . No correlation was observed between the degree of @entity82 and the degree of airflow limitation.

XXXX : varying presentations and clinicopathological correlation.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['Adventitial bronchiolar inflammation', 'bronchiolar inflammation', 'inflammation', 'subepithelial and adventitial inflammation'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis', 'bronchiolar fibrosis'] @entity133 :: ('MESH:D002282', 'Disease') :: ['bronchiolar lumina'] @entity5924 :: ('MESH:D001988', 'Disease') :: ['obliterative bronchiolitis'] @entity4595 :: ('MESH:D001987', 'Disease') :: ['bronchiectasis']
@entity5924 :: (MESH:D001988,Disease) :: ['Obliterative bronchiolitis']
