BACKGROUND: The aim of this retrospective study was to verify the role of renal biopsy in pregnancies complicated by @entity8 . METHODS: A series of 15 percutaneous renal biopsies performed in 15 pregnant @entity1 with @entity8 presenting during pregnancy over the past 10 years (1990-1999) were reviewed. RESULTS: All the @entity1 underwent renal biopsy before 30 weeks of gestation. The indications for renal biopsy were @entity8 of unknown cause or symptomatic @entity1985 ( @entity1985 ). @entity1 with @entity6064 were excluded. Eight @entity1 had @entity1988 , including five with diffuse crescenteric changes and three with a mesangial proliferative pattern. Three had chronic @entity631 (CGN), two had mesangial proliferative @entity631 and one each had @entity6 and endocapillary proliferative @entity631 . There were no significant complications except in one @entity1 who experienced gross @entity811 . Early induction of labor was recommended for the four @entity1 with @entity6 or CGM. The other 11 @entity1 received intravenous pulse @entity1667 or high dose oral @entity617 therapy. The responses to @entity134 therapy in these 11 @entity1 were as follows: five achieved complete remission of @entity1985 , three achieved incomplete remission, and three achieved partial remission. After 2 years' follow-up, seven mothers achieved complete remission, three had died, three developed @entity177 ( @entity177 ), and two progressed to end @entity177 (ESRF) requiring chronic hemodialysis. Fourteen of the 15 pregnancies resulted in live births and the other @entity1 was stillborn. CONCLUSIONS: Renal biopsy performed during pregnancy is not contraindicated. The results of histopathological studies are extremely useful in counseling regarding continuation or termination of pregnancy, potential maternal and fetal outcome, and recommending specific therapeutic modalities.

Renal biopsy in pregnancies complicated by undetermined XXXX .

@entity1 :: ('9606', 'Species') :: ['child', 'women', 'Patients', 'patients', 'patient'] @entity1667 :: ('MESH:D008775', 'Chemical') :: ['methylprednisolone'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal disease', 'renal dysfunction'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic nephrosclerosis'] @entity1988 :: ('MESH:D008181', 'Disease') :: ['lupus nephritis'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['steroid'] @entity177 :: ('MESH:D051437', 'Disease') :: ['stage renal failure', 'chronic renal failure', 'CRF'] @entity6064 :: ('MESH:D014115', 'Disease') :: ['toxemia'] @entity1985 :: ('MESH:D009404', 'Disease') :: ['NS', 'nephrotic syndrome'] @entity811 :: ('MESH:D006417', 'Disease') :: ['hematuria'] @entity631 :: ('MESH:D005921', 'Disease') :: ['glomerulonephritis'] @entity617 :: ('MESH:D011239', 'Chemical') :: ['prednisolone']
@entity8 :: (MESH:D007674,Disease) :: ['renal disease']
