It has been suggested that, apart from @entity130 , chronic straining at stool may also result in @entity16 , contributing to the etiology of genuine stress incontinence (GSI). The @entity14884 ( @entity14884 ) has been associated with rectal as well as @entity3134 , suggesting that connective tissue abnormalities may also be implicated. This study was undertaken in order to further investigate whether - and if so, why - an association may exist between symptoms of obstructive defecation, lifetime @entity1142 , chronic heavy lifting and lower urinary tract (LUT) dysfunction. Cases were female @entity1 referred for urodynamic assessment with symptoms of @entity5450 . Controls were age-, sex- and postcode-matched community controls. Both cases and controls were assessed using a detailed questionnaire that also asked about symptoms of @entity14884 . Cases were also divided into their urodynamic classification of @entity5450 . All symptoms of obstructive defecation (52.3% vs 33.6%, P=0.00003), as well as chronic straining at stool (38.6% vs 23.4%, P=0.0005), were significantly more common in @entity1 with @entity5450 than in community controls. @entity14884 , chronic heavy lifting and a history of @entity3134 were significantly associated with @entity1 with @entity5450 compared to those with @entity5450 alone. Overall, symptoms of obstructed defecation were not more prevalent in any one urodynamic diagnostic group than in others. However, childhood @entity1142 and current @entity1142 were significantly more prevalent in @entity1 with @entity409 than in those with other urodynamic diagnoses (16.7% vs 5.5%, P = 0.0030 and 13.0% vs 5.7%, P = 0.017). We concluded that @entity1 with @entity5450 are more likely to have symptoms of obstructive defecation than are community controls. Connective tissue disorders such as @entity14884 may be an important factor in this association.

The association of obstructive defecation, lower urinary tract dysfunction and the XXXX : a case-control study.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity16 :: ('MESH:D009422', 'Disease') :: ['pudendal nerve damage'] @entity409 :: ('MESH:D008107', 'Disease') :: ['voiding dysfunction'] @entity3134 :: ('MESH:D011391', 'Disease') :: ['uterovaginal prolapse'] @entity5450 :: ('MESH:D014570', 'Disease') :: ['LUT dysfunction', 'LUT and obstructive defecation'] @entity14884 :: ('MESH:D007593', 'Disease') :: ['benign joint hypermobility syndrome', 'BJHS'] @entity1142 :: ('MESH:D003248', 'Disease') :: ['constipation'] @entity130 :: ('MESH:D014947', 'Disease') :: ['obstetric trauma']
@entity14884 :: (MESH:D007593,Disease) :: ['benign joint hypermobility syndrome']
