BACKGROUND: Preterm birth defined as birth prior to 37 weeks of gestation is caused by different risk factors and implies an increased risk for @entity204 for the @entity1 . The aim of the study was to investigate the effect of maternal stress during pregnancy on the risk of @entity600 . METHODS: A case-control study that included 340 @entity1 ; 168 @entity1 who gave birth preterm and 172 @entity1 who gave birth at term. Data were manually extracted from standardized medical records. If the medical record contained a @entity146 diagnosis or a self-reported stressor e.g., @entity308 or @entity148 the @entity1 was considered to have been exposed to stress during pregnancy. Adjusted odds ratio (AOR) was used to calculate the attributable risk (AR) of maternal stress during pregnancy on @entity600 , both for the @entity1 exposed to stress during pregnancy ( @entity1452   =   (AOR-1)/AOR) and for the whole study population (AR2   =   @entity1452 *case fraction). RESULTS: Maternal stress during pregnancy was more common among @entity1 who gave birth preterm compared to @entity1 who gave birth at term (p   <0.000, AOR 2.15 (CI   =   1.18-3.92)). Among the @entity1 who experienced stress during pregnancy 54% gave birth preterm with stress as an attributable risk factor. Among all of the @entity1 the percentage was 23%. CONCLUSIONS: Stress seems to increase the risk of @entity600 . It is of great importance to identify and possibly alleviate the exposure to stress during pregnancy and by doing so try to decrease the @entity600 rate.

Effect of maternal stress during pregnancy on the risk for XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'child'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity146 :: ('MESH:D001523', 'Disease') :: ['psychiatric'] @entity600 :: ('MESH:D000014', 'Disease') :: ['preterm birth'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity1452 :: ('6942', 'Gene') :: ['AR1'] @entity204 :: ('MESH:D003643', 'Disease') :: ['disease and early death']
@entity600 :: (MESH:D000014,Disease) :: ['preterm birth']
