BACKGROUND: Photodynamic therapy (PDT) is a non-invasive method for topical and selective treatment of pre-malignant lesions of oral cavity. The aim of our study was to determine therapeutic response to PDT in @entity1 with @entity8407 . METHODS: Twelve @entity1 participated in our study. Lesions affected a variety of intraoral sites. The most common location was buccal, gingival and mandibular mucosa. @entity1 were treated with topically applied 10% @entity8454 (ALA) and light from an argon-pumped dye laser. Irradiation was performed in several (6-8) sessions using light at 635 nm wavelength, delivering a total dose of 100 J/cm2 per session. RESULTS: A complete response was obtained in 10 out of 12 treated @entity1 . One recurrence was observed during 6 months. CONCLUSION: Photodynamic therapy appears to be a feasible alternative to conventional therapy of pre-malignant lesions of oral cavity.

Photodynamic therapy (PDT) using topically applied @entity8454 (ALA) for the treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity8454 :: ('MESH:D000622', 'Chemical') :: ['delta-aminolevulinic acid'] @entity8407 :: ('MESH:D007972', 'Disease') :: ['oral leukoplakia']
@entity8407 :: (MESH:D007972,Disease) :: ['oral leukoplakia']
