BACKGROUND: The Scottish Government set out its policy on addressing the poor oral health of Scottish @entity1 in 2005. This led to the establishment of Childsmile, a national programme designed to improve the oral health of @entity1 in Scotland. One element of the programme promotes daily tooth brushing in all nurseries in Scotland (Childsmile Core). A second targeted component (Childsmile Nursery) offers twice-yearly application of @entity1388 varnish to @entity1 attending nurseries in deprived areas. Studies suggest that @entity1388 varnish application can reduce caries in both adult and @entity1 populations. This trial aims to explore the effectiveness and cost-effectiveness of additional preventive value @entity1388 varnish application compared to Childsmile Core. METHODS/DESIGN: The Protecting Teeth@3 Study is an ongoing 2  year parallel group randomised treatment as usual controlled trial. Three-year-old @entity1 attending the ante pre-school year are randomised (1:1) to the intervention arm ( @entity1388 varnish _ treatment as usual) or the control arm (treatment as usual). @entity1 in the intervention arm will have Duraphat   @entity1388 varnish painted on the primary tooth surfaces and will continue to receive treatment as usual: the core Childsmile Nursery intervention. @entity1 in the treatment as usual arm will receive the same series of contacts, without the application of varnish and will also continue with the Childsmile Core intervention. Interventions are undertaken by Childsmile trained extended duty dental nurses at six-monthly intervals. @entity1 receive a baseline dental inspection in nursery and an endpoint inspection in Primary 1 at the age of 5 years old. We will use primary and secondary outcome measures to compare the effectiveness of Duraphat   @entity1388 varnish plus treatment as usual with treatment as usual only in preventing any further @entity1547 . We will also undertake a full economic evaluation of the trial. TRIAL REGISTRATION: This study is registered at ClinicalTrials.gov. Number: NCT01674933 (24 August 2012).

Comparison of the caries-protective effect of XXXX varnish with treatment as usual in nursery school attendees receiving preventive oral health support through the Childsmile oral health improvement programme - the Protecting Teeth@3 Study: a randomised controlled trial.

@entity1 :: ('9606', 'Species') :: ['children', 'Children', 'Participants', 'child'] @entity1547 :: ('MESH:D003731', 'Disease') :: ['dental decay'] @entity1388 :: ('MESH:D005459', 'Chemical') :: ['fluoride']
@entity1388 :: (MESH:D005459,Chemical) :: ['fluoride']
