BACKGROUND: Managing @entity158 in residents of residential aged care facilities (RACFs) is challenging, especially for @entity1 with @entity303 . Clinicians must weigh the benefits of analgesic use against the potential for adverse events, particularly @entity25 . OBJECTIVES: The aim was to investigate the association between analgesic use and @entity25 in residents with and without @entity303 in RACFs. METHODS: This was a cross-sectional study of 383 permanent residents from six low-level and high-level RACFs in South Australia. Main measures included analgesic use in the previous 24  h, analgesic load and self-reported @entity25 . Covariates included relevant comorbidities ( @entity22 , @entity308 , @entity158 ), Charlson's Comorbidity Index, sedative load, self-reported and clinician-observed @entity158 and @entity303 severity. Logistic regression was used to compute odds ratios (ORs) and confidence intervals (CIs) for the association between analgesic use and @entity25 . RESULTS: Analgesics were used by 288 residents (75.2  %) in the previous 24  h. These included @entity1443 (n  =  264, 68.9  %), opioids (n  =  110, 28.7  %) and oral NSAIDs (n  =  14, 3.7  %). Overall, 116 (30.3  %) residents were categorized as having @entity25 . Of those with @entity303 , 77 (45.6  %) were categorized as having @entity25 . Opioid use in the previous 24  h was not associated with @entity25 in unadjusted or adjusted analyses. @entity1443 use was positively associated with @entity25 (OR 2.31; 95  % CI 1.20-4.42). CONCLUSION: Although @entity25 occurred in a large number of residents, especially those with @entity303 , this @entity25 was not necessarily associated with use of opioids. The risk of opioid-induced sedation may have been managed by strategies including preferential prescribing of @entity1443 to residents at risk of @entity25 , opioid discontinuation in residents who experienced @entity25 , and use of low doses of opioids.

Analgesic Use and Daytime Sleepiness in Residents With and Without XXXX in Residential Aged Care Facilities.

@entity1 :: ('9606', 'Species') :: ['people'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementia'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'painful conditions'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['Paracetamol', 'paracetamol'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleepiness', 'daytime sleepiness'] @entity22 :: ('MESH:D007319', 'Disease') :: ['insomnia']
@entity303 :: (MESH:D003704,Disease) :: ['Dementia']
