BACKGROUND: Infection-associated @entity631 is rare in adults and its long-term prognosis is undefined. METHODS: We retrospectively evaluated the clinical course of 50 adults (30 @entity1 , 20 @entity1 ) with @entity281 -associated @entity631 diagnosed in our department from 1979 to 1999. The mean follow-up was 90+/-78 months. @entity1 were subdivided into two groups: group 1 included those without underlying disease and group 2 included those with severe underlying disease. RESULTS: At presentation, the median age was 54 years, and 33 @entity1 were @entity101 , 31 had @entity751 , eight had @entity1985 and 11 had non-nephrotic @entity644 . @entity1 in group 2 were significantly older and had a significantly higher @entity644 than @entity1 of group 1. Of the 21 @entity1 in group 2, nine had @entity1575 , four @entity5 , five @entity6 , three @entity4595 , one thalassaemia intermedia, one @entity6558 and one had anti-phospholipid antibodies syndrome. At the last follow-up, five @entity1 had died, 21 @entity1 were in complete remission, ten had partial remission, ten had @entity177 and three were on chronic dialysis. Multivariate analysis showed that an underlying disease (P=0.04) and interstitial infiltration at biopsy (P=0.036) were predictors of incomplete recovery. A correlation analysis between the year of diagnosis and the clinical/ histological characteristics at presentation showed that age (P=0.05), @entity281 (P=0.01), underlying disease (P=0.01) and interstitial infiltration at biopsy (P=0.02) increased over time, while the number of @entity1 with complete remission significantly decreased (P=0.001). CONCLUSIONS: Infection-associated @entity631 may progress to @entity177 in a consistent number of adult hospitalized @entity1 , particularly in those with an underlying disease and when associated with interstitial infiltration at biopsy.

Long-term prognosis of @entity631 associated with XXXX in adults.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['liver cirrhosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal insufficiency', 'chronic renal failure'] @entity281 :: ('MESH:D007239', 'Disease') :: ['atypical infections', 'infection'] @entity4595 :: ('MESH:D001987', 'Disease') :: ['bronchiectasis'] @entity751 :: ('MESH:D013577', 'Disease') :: ['nephritic syndrome'] @entity1985 :: ('MESH:D009404', 'Disease') :: ['nephrotic syndrome'] @entity631 :: ('MESH:D005921', 'Disease') :: ['glomerulonephritis'] @entity6558 :: ('MESH:D017285', 'Disease') :: ['polymyositis']
@entity281 :: (MESH:D007239,Disease) :: ['infection']
