AIMS: In spite of the folkloric use of the root of Carpolobia lutea as a sexual stimulant in @entity1 , there has been limited scientific proof of its efficacy. This study compares the efficacy of @entity1042 extract of C. lutea root (MECLR) and @entity7855 on the sexual activity of male @entity95 . METHODS: 20 adult male @entity95 were grouped into four of five @entity95 each. Groups 1-4 were treated orally for 28 days with 2 ml/kg 1% @entity9266 (vehicle), 40 mg/kg MECLR, 80 mg/kg MECLR, and 0.5 mg/kg @entity7855 (SC), respectively. Sexual activities of males from each group were assessed by cohabiting them with sexually receptive female at estrus on days 0, 1, 3, and 5 using digital camera mounted on mating arena. Serum @entity251 and @entity842 concentration of the corpora cavernosa homogenates were also determined. RESULTS: MECLR caused a dose-dependent significant increase in mount frequency, intromission frequency and ejaculatory latency (EL) while it reduced mount latency, intromission latency and post EL (similar to SC) when compared with the control. MECLR also caused significant increase in @entity842 concentration in corpora cavernosa but no change in serum @entity251 concentration. CONCLUSIONS: Results suggest that MECLR enhances male sexual activity possibly by augmenting @entity842 concentration. This study thus provides a novel scientific rationale for the use of C. lutea in the management of penile @entity323 and impaired libido.

Comparative evaluation of the aphrodisiac efficacy of XXXX and Carpolobia lutea root extract in male @entity95 .

@entity1 :: ('9606', 'Species') :: ['man'] @entity251 :: ('MESH:D013739', 'Chemical') :: ['testosterone'] @entity323 :: ('MESH:D007172', 'Disease') :: ['erectile dysfunction'] @entity1042 :: ('MESH:D000432', 'Chemical') :: ['methanol'] @entity95 :: ('9986', 'Species') :: ['rabbits'] @entity7855 :: ('MESH:C101426', 'Chemical') :: ['sildenafil', 'sildenafil citrate'] @entity842 :: ('MESH:D009569', 'Chemical') :: ['nitric oxide'] @entity9266 :: ('MESH:D011136', 'Chemical') :: ['Tween-20']
@entity7855 :: (MESH:C101426,Chemical) :: ['sildenafil']
