BACKGROUND: Endoscopic submucosal dissection (ESD) - initially developed for the treatment of early @entity356 in Japan - is an attractive option for en bloc resection of larger sessile or flat @entity14 . METHODS: A review of the current literature on colorectal ESD was carried out. RESULTS: In contrast to conventional endoscopic mucosal resection (EMR), ESD for larger @entity14 yields high en bloc resection rates and very low recurrence rates. The frequency of delayed @entity548 is similar for EMR and ESD. Higher perforation rates during ESD are mostly due to microperforations identified and treated during the intervention, and are therefore of minor clinical relevance. A major disadvantage of ESD is the necessity for high-level endoscopic skills and long procedure times. ESD also has the potential to replace laparoscopic surgery or transanal endoscopic microsurgery mainly due to its lower complication rates. CONCLUSION: ESD for the resection of larger flat or sessile colorectal lesions has potential advantages over conventional EMR or minimally invasive surgery. Due to the low incidence of early @entity356 , experience with ESD will remain limited in Western countries. The spread of colorectal ESD will depend on adequate training opportunities and also on modifications yielding a reduction in procedure time.

Endoscopic Submucosal Dissection (ESD) in XXXX .

@entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal neoplasia'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding']
@entity14 :: (MESH:D015179,Disease) :: ['Colorectal Tumors']
