BACKGROUND: Increased blood pressure (BP) in young adulthood is associated with @entity65 and mortality. Longitudinal studies of @entity1 at young ages are, however, limited. Our aim was to study the relationships of adolescent BP and tracking of BP into young adulthood with subclinical @entity731 , as assessed by @entity1004 ( @entity1004 ), at the age of 28 years. METHODS: The @entity731 Risk in Young Adults (ARYA) study comprises of a community-based sample of 750 subjects aged 27 to 30 years. In the 352 @entity1 and 398 @entity1 , at least one BP measurement was recorded at a mean age of 13 years in school health records. Recently, all @entity1 completed a questionnaire on cardiovascular risk factors, had a fasting blood sample drawn, and underwent an ultrasound examination of both common carotid arteries to assess @entity1004 . RESULTS: Linear regression showed that adolescent systolic BP was associated with thickening of the intima-media (an increase of 7.5 microm in @entity1004 per standard deviation increase in systolic BP; 95% CI 4.3 to 10.6). Similar relations were found for pulse pressure and mean arterial pressure. When sex, age, and body mass index at adolescence and young adulthood and adult BP were taken into account, the relations attenuated, but for pulse pressure they remained statistically significant. Furthermore, subjects who tracked in the highest systolic BP and pulse pressure levels from adolescence into young adulthood showed the thickest @entity1004 . CONCLUSION: Our findings strengthen the notion that elevated BP at adolescence and a relative increase in BP from adolescence to adulthood unfavorably affect cardiovascular risk, as indicated by increased @entity1004 .

Adolescent blood pressure and blood pressure tracking into young adulthood are related to subclinical @entity731 : the XXXX Risk in Young Adults (ARYA) study.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'patients', 'men'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis', 'Atherosclerosis'] @entity1004 :: ('MESH:C563733', 'Disease') :: ['carotid intima-media thickness', 'CIMT'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular morbidity']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerosis']
