BACKGROUND AND PURPOSE: Variable sex differences in clinical outcomes after @entity64 have been reported worldwide. This study aimed to elucidate whether sex is an independent risk factor of poor functional outcome after acute @entity385 . METHODS: Using the database of @entity1 with @entity64 registered in the Fukuoka @entity64 Registry in Japan from 1999 to 2013, 6236 previously independent @entity1 with first-ever @entity385 who were admitted within 24 hours of onset were included in this study. Baseline characteristics were assessed on admission. Study outcomes included @entity16 , @entity16 , and poor functional outcome (modified Rankin Scale score, 3-6 at discharge). Logistic regression analyses were performed to evaluate the association between sex and clinical outcomes. RESULTS: Overall, 2398 @entity1 (38.5%) were @entity1 . Severe @entity64 (National Institutes of Health @entity64 Scale score, >= 8) on admission was more prevalent in @entity1 than in @entity1 . The frequency of @entity16 or deterioration during hospitalization was not different between the sexes. After adjusting for possible confounders, including age, @entity64 subtype and severity, risk factors, and poststroke treatments, it was found that female sex was independently associated with poor functional outcome at discharge (odds ratio, 1.30; 95% confidence interval, 1.08-1.57). There was heterogeneity of the association between sex and poor outcome according to age: @entity1 had higher risk of poor outcome than @entity1 among @entity1 aged >= 70 years, but no clear sex difference was found in @entity1 aged <70 years. CONCLUSIONS: Female sex was associated with the risk of poor functional outcome at discharge after acute @entity385 .

Sex Differences in Short-Term Outcomes After Acute XXXX : The Fukuoka @entity64 Registry.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological deterioration', 'neurological improvement'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'Stroke', 'acute stroke'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['Ischemic Stroke']
