BACKGROUND: Superior @entity158 control has been suggested with transversus abdominis plane blocks, but evidence-based recommendations for transversus abdominis plane blocks and their effects on @entity1 outcomes are lacking. OBJECTIVE: The aim of this study was to determine whether transversus abdominis plane blocks improve early postoperative outcomes in @entity1 undergoing laparoscopic colorectal resection already on an optimized enhanced recovery pathway. DESIGN: This study is based on a prospective, randomized, double-blind controlled trial. SETTINGS: The trial was conducted at a tertiary referral center. @entity1 : @entity1 undergoing elective laparoscopic colorectal resection were selected. INTERVENTIONS(S): @entity1 were randomly assigned to receive either a transversus abdominis plane block or a placebo placed intraoperatively under laparoscopic guidance. All followed a standardized enhanced recovery pathway. @entity1 demographics, perioperative procedures, and postoperative outcomes were collected. MAIN OUTCOME MEASURES: @entity282 and @entity390 / @entity391 scores in the postanesthesia care unit and department, opioid use, length of stay, and 30-day readmission rates were measured. RESULTS: The trial randomly assigned 41 @entity1 to the transversus abdominis plane block group and 38 @entity1 to the control group. Demographic, clinical, and procedural data were not significantly different. In the postanesthesia care unit, the transversus abdominis plane block group had significantly lower @entity158 scores (p < 0.01) and used fewer opioids (p < 0.01) than the control group; @entity1209 were comparable (p = 0.99). The transversus abdominis plane group had significantly lower @entity158 scores on postoperative day 1 (p = 0.04) and throughout the study period (p < 0.01). There was no significant difference between groups in postoperative opioid use (p = 0.65) or @entity390 / @entity391 (p = 0.79). The length of stay (median, 2 days experimental, 3 days control; p = 0.50) and readmission rate (7% experimental, 5% control, p = 0.99) was similar across cohorts. LIMITATIONS: This study was conducted a single center. CONCLUSIONS: Transversus abdominis plane blocks improved immediate short-term opioid use and @entity158 outcomes. @entity158 improvement was durable throughout the hospital stay. However, the blocks did not translate into less overall narcotic use, shorter length of stay, or lower readmission rates.

The effect of transversus abdominis plane blocks on XXXX in laparoscopic colorectal surgery: a prospective, randomized, double-blind trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'PATIENTS', 'Patient'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'early pain', 'pain'] @entity282 :: ('MESH:D010149', 'Disease') :: ['Postoperative pain'] @entity1209 :: ('MESH:D020250', 'Disease') :: ['postoperative nausea/vomiting scores']
@entity282 :: (MESH:D010149,Disease) :: ['postoperative pain']
