OBJECTIVE: The extent of sonomorphologic differences of peripheral nerves between CMT and @entity7577 is unknown. METHODS: We recruited 9 @entity1 with CMT-1A and 9 with @entity7577 . @entity1 underwent a standardized sonographic protocol, which evaluated nerve size and vascularization. We quantitatively assessed fascicle size and echogenicity. RESULTS: All 18 @entity1 @entity1283 , but no increased vascularization. @entity7577 demonstrated larger nerves at sites of entrapment (median nerve at the carpal tunnel p=0.049, ulnar nerve at the sulcus p<0.001), greater swelling ratios of median (p<0.001), ulnar (p=0.017) and fibular nerve (p=0.005) than CMT-1A. CMT-1A revealed larger nerves proximal to sites of entrapment (median and fibular nerve, brachial plexus p<0.001). Nerve fascicles where larger (p<0.001) and more hypo-echogenic in CMT-1A. Nerve, fascicle size nor echogenicity correlated with age, gender or MRC sum-score. CONCLUSIONS: Ultrasonography of nerves reveals specific phenotypes differentiating CMT-1A from @entity7577 . In CMT-1A enlargement of nerves and fascicles is multifocal among multiple nerves, whereas in @entity7577 is restricted to sites of entrapment. SIGNIFICANCE: Our findings of specific sonomorphological phenotypes, differentiating CMT-1A from @entity7577 , may help to improve our pathophysiological insights in CMT and @entity7577 .

Distinctive patterns of XXXX in Charcot-Marie-Tooth type 1A and hereditary neuropathy with pressure palsies.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity7577 :: ('MESH:C536965', 'Disease') :: ['HNPP nerve enlargement', 'HNPP'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['demonstrated nerve enlargement']
@entity1283 :: (MESH:D006332,Disease) :: ['sonographic nerve enlargement']
