PURPOSE: Standard gamble (SG) is the preferred method of assessing preferences in situations with uncertainty and risk, which makes it relevant to @entity1 considered for aortic valve replacement (AVR). The present study assesses SG preferences in @entity1 with severe @entity472 ( @entity472 ). METHODS: All @entity1 >18  years old with severe @entity472 referred for AVR to our institution were invited to enroll in the study. The SG was administered by a clinical research nurse. The SF-36, EQ-5D 3L, Hospital Anxiety and @entity308 Scale (HADS), and @entity472 symptoms were administered by self-completed questionnaire. We hypothesized that SG utilities would have low-to-moderate correlations with physical and mental aspects of health based on our pathophysiological understanding of severe @entity472 . No correlations were expected with echocardiographic measures of the aortic valve. RESULTS: The response rate for SG was 98  %. SG moderately correlated with physical aspects of SF-36 (PCS, role-physical, vitality), health transition, @entity472 symptoms, and EQ-VAS (   S  =  0.31-0.39, p  <  0.001) and had low correlation with mental aspects of SF-36 and EQ-5D (   S  =  0.17-0.28, p  <  0.001). No correlation was found between SG and HADS, echocardiographic measures, age, gender, or education level (   S  =  0.01-0.06). CONCLUSIONS: SG is an acceptable and feasible method of assessing preferences in @entity1 with severe @entity472 that has evidence for validity. The inclusion of uncertainty lends the SG face validity in this population as a direct approach to assessing preferences and basis for QALY calculations.

Validity of standard gamble utilities in XXXX referred for aortic valve replacement.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity472 :: ('MESH:D001024', 'Disease') :: ['aortic stenosis', 'AS'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression']
@entity1 :: (9606,Species) :: ['patients']
