BACKGROUND: Despite advances in therapeutic strategies and improved guidelines, morbidity and mortality rates for out-of-hospital @entity1167 (OHCA) remain high. Especially, neurological prognosis is one of the most important problems even though brain protection therapy for @entity1 with OHCA has improved greatly in recent years due to the development of emergency post- @entity1167 interventions such as mild @entity2332 , early percutaneous coronary intervention, and extracorporeal cardiopulmonary resuscitation (CPR). Recently, cerebral regional @entity26 saturation (rSO2) has received attention as a method for evaluation of cerebral oxygenation. We have reported that conventional chest compression did not improve the rSO2 of @entity1167 @entity1 if they did not achieve return of spontaneous circulation. It is, however, unclear whether a mechanical CPR device is helpful in improving rSO2. The purpose of this study was to evaluate the effects of load-distributing-band CPR (LDB-CPR) on rSO2. METHODS: In this prospective study, LDB-CPR was begun for OHCA with the AutoPulse(TM) device on @entity1 arrival at hospital. During mechanical CPR, rSO2 values were recorded continuously from the forehead of the @entity1 . CPR for @entity1 with OHCA was performed according to the Japan Resuscitation Council Guidelines 2010 except for using the AutoPulse(TM) instead of manual chest compression. RESULTS: From December 2012 to December 2013, 34 @entity1 (mean age, 75.6        12.8  years) with OHCA were included in this study. Duration of time from recognition of @entity299 to arrival to hospital was 31.0        11.4  min. Compared with the rSO2 value of 38.9        0.7  % prior to starting LDB-CPR, rSO2 values at 4, 8 and 12  minutes increased significantly after initiation of LDB-CPR (44.0        0.9  %, 45.2        0.8  %, and 45.5        0.8  %, respectively, p   <   0.05). CONCLUSION: LDB-CPR significantly increased the rSO2 of @entity1167 @entity1 during resuscitation.

Load-distributing-band cardiopulmonary resuscitation for out-of-hospital XXXX increases regional cerebral oxygenation: a single-center prospective pilot study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac collapse'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['cardiac arrest'] @entity2332 :: ('MESH:D007035', 'Disease') :: ['therapeutic hypothermia']
@entity1167 :: (MESH:D006323,Disease) :: ['cardiac arrest']
