PURPOSE: To evaluate the tracheal intubating conditions when intubation time is determined by the onset time of the @entity4094 either of the adductor pollicis (AP) or of the orbicularis oculi muscle (OO). METHODS: In this prospective, double blind, randomised study, 40 adults ASA I-II undergoing general anaesthesia with tracheal intubation were allocated to two groups (n = 20) according to the reference muscle (AP or OO) used to determine the appropriate intubation time. Induction of anaesthesia was achieved with 5-7 mg.kg-1 @entity4490 , 1.5-2.5 micrograms.kg-1 @entity3575 and 0.9 mg.kg-1 @entity2898 (3 x ED95) for muscular relaxation. Supramaximal train of four stimulation of the ulnar and facial nerve every 10 sec was used to monitor the @entity4094 . After @entity227 or OO contraction, tracheal intubation and quality of intubation assessment were performed by two independent anaesthetists. Data are expressed as mean and standard error of the mean (X +/- SEM). RESULTS: Curarisation time of the OO was shorter (110 +/- 4.9 sec) than that of the AP (144 +/- 5.5 sec; P < 0.0001). Intubation conditions were excellent in 95% and good in 5% of the @entity1 in the AP group whereas in the OO group only 65% of the @entity1 had excellent and 20% good intubation conditions (P < 0.05). Coughing was observed in 15% of @entity1 in the OO group during tracheal intubation. CONCLUSION: Monitoring neuro-muscular activity of the AP using TOF to determine the appropriate tracheal intubation time and conditions in @entity1 paralysed with rocurorium is more clinically relevant than monitoring the OO muscle.

[Assessment of intubation time and conditions under the influence of XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4094 :: ('MESH:D009468', 'Disease') :: ['neuromuscular block'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual loss of AP'] @entity4490 :: ('MESH:D013874', 'Chemical') :: ['thiopentone'] @entity2898 :: ('MESH:C061870', 'Chemical') :: ['rocuronium'] @entity3575 :: ('MESH:D005283', 'Chemical') :: ['fentanyl']
@entity2898 :: (MESH:C061870,Chemical) :: ['rocuronium']
