OBJECTIVE: Eosinophilic @entity102 (ECRS) is as a subgroup of @entity102 ( @entity102 ) with @entity480 . ECRS is a refractory disease closely related to @entity565 . Fractionated exhaled @entity842 (FeNO) levels were reportedly elevated in some @entity748 with @entity102 after adequate treatment, suggesting that residual eosinophilic airway inflammation or ECRS might affect FeNO levels. METHODS: To investigate the association between @entity565 with ECRS and FeNO levels, we examined FeNO levels in 133 @entity748 (99 with ECRS and 34 without ECRS) and 13 @entity1 with ECRS without @entity565 . The severity of @entity565 was defined by the Global Initiative for Asthma guidelines and that of @entity1244 was evaluated by the sinus CT score based on the Lund-Mackay scale. RESULTS AND CONCLUSIONS: FeNO levels were elevated even in well-controlled @entity748 with ECRS, whereas @entity748 without ECRS and ECRS @entity1 without @entity565 did not have high FeNO levels (>50   ppb). Although FeNO levels were not correlated with @entity565 severity, they were positively correlated with the sinus CT score. In @entity748 with ECRS, @entity1 with higher FeNO levels had more severe ECRS and @entity565 . There is a possibility of having comorbid ECRS, particularly in @entity748 with high FeNO levels even after adequate treatment, including ICS, suggesting that @entity565 and ECRS may be closely associated as one @entity1030 with @entity32 . Continual awareness of the coexistent ECRS is ideally recommended for @entity748 with high FeNO levels.

Residual exhaled XXXX elevation in @entity748 is associated with eosinophilic @entity102 .

@entity748 :: ('MESH:D013224', 'Disease') :: ['asthmatics'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity1244 :: ('MESH:D012852', 'Disease') :: ['sinusitis'] @entity32 :: ('MESH:D007249', 'Disease') :: ['eosinophilic inflammation'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma', 'bronchial asthma'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic rhinosinusitis', 'CRS'] @entity842 :: ('MESH:D009569', 'Chemical') :: ['nitric oxide'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['airway disease'] @entity480 :: ('MESH:D009298', 'Disease') :: ['nasal polyps']
@entity842 :: (MESH:D009569,Chemical) :: ['nitric oxide']
