STUDY OBJECTIVE: To compare the effect of high-frequency oral airway oscillation, high-frequency chest wall oscillation, and conventional chest physical therapy ( @entity1191 ) on weight of expectorated sputum, pulmonary function, and @entity26 saturation in outpatients with stable @entity1577 ( @entity1577 ). DESIGN: Prospective randomized trial. SETTING: Pediatric pulmonary division of a tertiary care center. @entity1 : Fourteen outpatients with stable @entity1577 recruited from the @entity1577 center. INTERVENTIONS: Two modes of oral airway oscillation (1: frequency 8 Hz; inspiratory to expiratory [I:E] ratio 9:1; 2: frequency 14 Hz; I:E ratio 8:1), two modes of chest wall oscillation (1: frequency 3 Hz; I:E ratio 4:1; 2: frequency 16 Hz; I:E ratio 1:1, alternating with frequency 1.5 Hz, I:E ratio 6:1), and @entity1191 (clapping, vibration, postural drainage, and encouraged coughing) were applied during the first 20 min of 4 consecutive hours. MEASUREMENTS AND RESULTS: Sputum was collected on an hourly basis for a total of 6 consecutive hours. During the first and the last hour, @entity1 collected sputum without having any treatment and underwent pulmonary function tests (PFTs). @entity26 saturation was measured at 30-min intervals during hours 1 to 6. For the first 20 min of the second to the fifth hour, @entity1 received one of the treatments. To assess the effect of the intervention, the weight of expectorated sputum during hours 2 to 6 was averaged and expressed as percentage of the weight expectorated during the first hour (baseline). For the five treatment modalities, mean sputum dry and wet weights ranged between 122% and 185% of baseline. There was no statistically significant difference among the treatment modalities. As measured by sputum wet weight, all oscillatory devices tended to be less effective than @entity1191 (p=0.15). As measured by dry weight, oral airway oscillation at 8 Hz with an I:E ratio of 9:1 and @entity1191 tended to be more effective than the other treatment modalities (p=0.57). None of the treatment modalities had an effect on PFTs and @entity26 saturation and all were well tolerated. CONCLUSION: In outpatients with stable @entity1577 , high-frequency oscillation applied via the airway opening or via the chest wall and @entity1191 have comparable augmenting effects on expectorated sputum weight without changing PFTs or @entity26 saturation. In contrast to @entity1191 , high-frequency oral airway and @entity764 are self-administered, thereby containing health-care expenses.

Effect of high-frequency oral airway and chest wall oscillation and conventional chest physical therapy on expectoration in @entity1 with stable XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen', 'Oxygen'] @entity1191 :: ('CHEBI:27656', 'Chemical') :: ['CPT'] @entity764 :: ('MESH:D013898', 'Disease') :: ['chest wall oscillations'] @entity1577 :: ('MESH:D003550', 'Disease') :: ['CF', 'cystic fibrosis']
@entity1577 :: (MESH:D003550,Disease) :: ['cystic fibrosis']
