Endometriosis originates in the uterine lining and affects ~20% of reproductive-age @entity1 . The disease often causes chronic @entity2371 , affects ovulatory function and influences fertility. Although laparoscopic diagnosis of uterine @entity46 is quite specific, direct visualisation can be difficult or inaccurate in some circumstances, and it is not useful for diagnosing extra-abdominal disease. Laparoscopy is an invasive procedure, has significant morbidity and cannot be carried out frequently to monitor efficacy of therapy and the possibility of recurrence. Thus, a specific, non-invasive diagnostic test is required. One intriguing area of research uses the technology of radioimmunotargeting, which has previously been used for @entity5 detection. This technique could have potential for the specific detection and eventual treatment of @entity46 . A marker, @entity29074 ( @entity29074 ), has been identified that is expressed in ~90% of @entity46 specimens, and is not expressed or only weakly expressed in normal endometrium. The US Food and Drug Administration has approved a monoclonal antibody to @entity29074 for investigation as an immunoimaging agent in @entity5 that exhibit @entity1712 . @entity29074 targeting using this antibody could be useful for detecting and/or treating @entity46 .

Unique molecular markers in XXXX @entity46 : implications for diagnosis and therapy.

@entity1 :: ('9606', 'Species') :: ['women'] @entity1712 :: ('MESH:D004802', 'Disease') :: ['eosinophilia'] @entity29074 :: ('8288', 'Gene') :: ['eosinophil peroxidase', 'EPO'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'cancer'] @entity2371 :: ('MESH:D017699', 'Disease') :: ['pelvic pain'] @entity46 :: ('MESH:D004715', 'Disease') :: ['endometriosis']
@entity1 :: (9606,Species) :: ['human']
