BACKGROUND: This study compares esophageal pH-monitoring parameters of @entity1 with @entity354 ( @entity354 ) with or without @entity357 ( @entity357 ) and determines the outcome of those with @entity354 and @entity357 . METHODS: Among 718 @entity1 with @entity354 , 45 @entity1 (6%) with associated @entity357 were retrospectively studied. They were divided into those with @entity16 ( @entity16 , n = 35) and those with @entity16 ( @entity16 , n = 10). The pH-monitoring parameters of 27 of these (60%) were compared with pH-monitoring parameters of 27 control @entity1 who had @entity354 without @entity357 . RESULTS: Esophageal clearance was longer in @entity1 with @entity357 compared with those without @entity357 (P < 0.05). All 35 @entity16 @entity1 underwent a trial of conservative treatment, which failed in 9 @entity1 (25.7%). Surgery was the initial treatment in 8 @entity16 @entity1 . Follow-up was available in 20 @entity16 and 10 @entity16 @entity1 . Nine of 11 conservatively treated @entity16 @entity1 improved. All @entity16 (n = 9) and @entity16 (n = 8) @entity1 who underwent surgery improved. Conservative treatment failed in 2 @entity16 and in 2 @entity16 @entity1 . CONCLUSIONS: Presence of @entity357 in @entity1 with @entity354 is associated with prolonged exposure of the esophagus to acid and a high failure rate of nonoperative treatment. However, medical treatment should be tried in @entity16 @entity1 despite the significant failure rate.

@entity357 in XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity16 :: ('MESH:D009422', 'Disease') :: ['ND', 'neurologically normal development', 'NN', 'neurologic disorders'] @entity357 :: ('MESH:D006551', 'Disease') :: ['HH', 'hiatal hernia'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux', 'GER']
@entity354 :: (MESH:D005764,Disease) :: ['pediatric gastroesophageal reflux']
