Our aim was to determine the frequency of @entity4 ( @entity4 ) in @entity1 with @entity5576 ( @entity5576 ). We evaluated 30 @entity1 with @entity5576 for evidence of @entity4 by comparing @entity1372 and water excretion in the recumbent and standing postures and morning and evening body weights. Data were compared with findings in 30 @entity1 with @entity4 , 22 weight-matched obese normal subjects, and 20 lean normal subjects. The effect of treatment with diuretics or diuretics plus sympathomimetic agents was compared. Seventy-seven percent of @entity5576 @entity1 had evidence of peripheral @entity4 and 80% had significant orthostatic retention of @entity1372 or water. Excretion of a standard saline load and of a tap water load was significantly impaired in the upright posture in the @entity5576 and @entity4 @entity1 compared with the lean and obese normal subjects. Diuretic therapy induced @entity353 (up to 9 kg) and decreased mean @entity1017 from morning to evening in 5 of 12 @entity1 treated. In seven @entity1 also treated with diuretics plus sympathomimetic drugs, the diuretic-induced morning @entity353 and morning to evening @entity1017 were both significantly improved with the addition of sympathomimetic agents. Therapy reduced the frequency or severity of @entity10 in seven @entity1 and reduced @entity1829 in four @entity1 who received no other concurrent treatment for @entity5576 . The orthostatic retention of @entity1372 and water and the consequent @entity4 is very similar in @entity5576 and @entity4 @entity1 , suggesting a common pathogenesis for both disorders. Diuretic therapy, dietary salt and water restriction, and planned periods of recumbency merit study as a treatment for these @entity1 .

@entity5576 and XXXX may share a common pathogenesis.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity4 :: ('MESH:D004487', 'Disease') :: ['OE', 'orthostatic edema', 'edema'] @entity1372 :: ('MESH:D012964', 'Chemical') :: ['sodium'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity1829 :: ('MESH:D010211', 'Disease') :: ['papilledema'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headaches'] @entity5576 :: ('MESH:D011559', 'Disease') :: ['idiopathic intracranial hypertension', 'IIH']
@entity4 :: (MESH:D004487,Disease) :: ['orthostatic edema']
