An @entity2548 ( @entity2548 ) is an abnormal connection between an artery and a vein, whereby the interconnecting capillary network is missing. Such a @entity600 frequently occurs in the deep midline regions of the brain, and the subsequent increased flow into the draining vein of Galen substantially dilates in an aneurysmal manner. Congenital forms of the @entity384 of the vein of Galen (AVG) often lead to death in the neonatal period, predominantly due to @entity712 caused by the increased venous inflow as a consequence of the intracerebral arteriovenous shunting. In the presented case a male baby suffered from a rare combination of a cerebral @entity2548 and an @entity118 ( @entity118 ). He was born at week 38 of pregnancy and subsequently developed tachydyspnoe. Ultrasound (US) and CT scans revealed a large bilateral @entity2548 with dilated basal venous sinuses, @entity1276 and @entity1010 . In the heart, severe @entity8158 , @entity2461 and an @entity118 were detectable by US. Neurosurgical consultation rejected the possibility of an operative treatment due to size and localization of the lesion and the existing irreversible @entity75 . The @entity1 died because of @entity712 6 days after birth. Autopsy examination in the brain demonstrated a large conglomerate of dilated blood vessels predominantly in the midline and left occipital lobe, @entity4 and @entity1276 . In the heart, the @entity118 detected by US proved to be an ostium secundum-type lesion. Histologically, the conglomerate of vessels revealed features of an @entity2548 and matched the characteristics of AVG. Consequences of chronic @entity2806 were also present, with ferruginated neurons suggesting intrauterine damage caused by a congenital @entity2548 . Based on data in the literature, we assume that the left-to-right shunt due to increased venous influx into the heart caused not only @entity1283 , but may have also interfered with the normal development of the @entity955 leading to an @entity118 , contributing to the rapid progression of the @entity712 .

Vein of Galen malformation combined with XXXX in a neonate.

@entity1 :: ('9606', 'Species') :: ['child'] @entity712 :: ('MESH:D006333', 'Disease') :: ['cardiac failure'] @entity1276 :: ('MESH:D006849', 'Disease') :: ['hydrocephalus'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['ischemic brain injury'] @entity75 :: ('MESH:D001927', 'Disease') :: ['brain damage'] @entity384 :: ('MESH:D002311', 'Disease') :: ['aneurysmal dilatation'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['cardiomegaly'] @entity2461 :: ('MESH:D004374', 'Disease') :: ['patent ductus arteriosus'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformation'] @entity8158 :: ('MESH:D017380', 'Disease') :: ['right ventricular hypertrophy'] @entity1010 :: ('MESH:C566985', 'Disease') :: ['brain atrophy'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial septum'] @entity118 :: ('MESH:D006344', 'Disease') :: ['atrial septal defect', 'ASD'] @entity2548 :: ('MESH:D001164', 'Disease') :: ['AVF', 'arteriovenous fistula']
@entity118 :: (MESH:D006344,Disease) :: ['atrial septal defect']
