In this study, the extent to which @entity2845 in @entity1 with @entity191 can be influenced by practice and by specific training strategies was investigated. Fifteen @entity1 with @entity191 tested after withdrawal of anti-Parkinson medication, and 15 matched control subjects, practised a ballistic aiming task. Performance was tested before, during and after training and again 1 h later. The @entity191 @entity1 and control subjects were randomly assigned to one of two training schedules, practising with or without rhythmic auditory cues. At baseline, the @entity191 @entity1 showed longer movement times, with a marked decrease in maximum acceleration and deceleration in the initial open-loop phase compared with those of the control subjects. With training, they were able to make significant improvement in the speed of aimed movements, particularly in the early movement phase, without any deterioration in accuracy. These effects transferred to an untrained limb and were at least partially maintained after a 1-h delay. While @entity1 remained impaired relative to control subjects at all phases of training and follow-up, the @entity1 ' performance at the end of training did not differ significantly from the control subjects' baseline function. Contrary to expectation, rhythmic auditory cues did not enhance improvement in the speed of aimed movements in either @entity1 or control subjects. If anything, less improvement was shown in the cued groups, although there were suggestions that the aiming skill was retained better over the delay period. The results demonstrate preserved abilities to improve speed of single ballistic aiming movements in @entity191 @entity1 and the possibility of reducing @entity2845 by training.

Training improves the speed of aimed movements in XXXX .

@entity2845 :: ('MESH:D018476', 'Disease') :: ['bradykinesia'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease", "idiopathic Parkinson's disease"]
@entity191 :: (MESH:D010300,Disease) :: ['Parkinson's disease']
