BACKGROUND/AIMS: Radiofrequency ablation (RFA) has been proven effective for treating @entity157 ( @entity157 ) nodules. However, post-RFA local recurrence is a major factor limiting prognosis. Up to now, there is no consensus on a standardized treatment strategy for these local recurrences. The aim of this study is to evaluate the outcomes of salvage treatments for RFA-related local recurrence. METHODS: From May 2008 to June 2013, a total of 112 @entity1 with @entity157 were detected with local recurrence after RFA. Among them, 94 @entity1 received sequential treatments in our hospital, including salvage resection (SR) (n   =   24), salvage liver transplantation (n   =   2), repeated RFA (n   =   62), and transarterial chemoembolization (TACE) (n   =   6). We evaluated the treatment outcomes of @entity1 by @entity1104 ( @entity1104 ), RFA, and TACE. RESULTS: The median follow-up time was 32  months. After treatment, local recurrence was eradicated in 82 of 94 @entity1 (87.2  %). The complete response (CR) rate in the RFA group was 90.3  % (56/62), while it was 100  % (26/26) in the @entity1104 group (P   =   0.175) and 0  % (0/6) in the TACE group. When analysis confined to @entity1 with CR, the 1- and 3-year disease-free survival (DFS) rates were 57.7 and 20.2  % in the @entity1104 group, and 41.7 and 28.6  % in the RFA group, respectively (P   =   0.640). The 1- and 3-year overall survival (OS) rates were 93.3 and 69.1  % in the @entity1104 group, and 78.6 and 57.5  % in the RFA group, respectively (P   =   0.251). CONCLUSION: Repeated RFA is the first treatment choice for @entity1 with post-RFA local recurrence. @entity1104 should be considered when RFA failed or is inapplicable.

Local Recurrence after Radiofrequency Ablation of XXXX : Treatment Choice and Outcome.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'small hepatocellular carcinoma'] @entity1104 :: ('MESH:D000267', 'Disease') :: ['salvage surgery', 'SS']
@entity157 :: (MESH:D006528,Disease) :: ['Hepatocellular Carcinoma']
