BACKGROUND: Heavy menstrual @entity548 of endometrial origin (HMB) is a major healthcare problem in premenopausal @entity1 and affects several aspects of @entity1 's health and quality of life (QoL). The aim of this study was to compare the efficacy of Persian Golnar (PG) and @entity927 (TA) on heavy menstrual @entity548 of endometrial origin (HMB) and @entity1 ' QoL. METHODS: A double-blind randomized controlled trial with parallel design and block randomization technique was conducted. A total of 94 @entity1 with HMB were randomly assigned to take either PG or TA for 5 days from day 1 of menses for three consecutive menstrual cycles. @entity190 was measured by the pictorial @entity190 assessment chart (PBAC). Hematological assessments were made before the intervention and after treatment. QoL as a secondary outcome was evaluated using SF-36 and the @entity931 questionnaire (MQ). Statistical analysis was performed using t-test, paired ttest,   2 test, Mann-Whitney test, and Wilcoxon signed-rank test. RESULTS: In each group, 38 @entity1 (80.8%) completed the 3-month follow-up. Both PG and TA reduced @entity190 . PBAC mean (SD) score was reduced from @entity55870 (96.07) after the third treatment cycle, respectively (p< 0.001). Furthermore, mean hemoglobin, Hb (SD) concentrations in the PG and TA groups increased significantly from 12.06 (0.86) and 11.53 (0.86)mg/dl to 13.02 (0.82) and 12.72 (0.88) mg/dl (p< 0.001). QoL was significantly improved in both groups (p< 0.001). However, there were no significant differences between the groups after the intervention. CONCLUSION: The results of the present study demonstrate the efficacy of PG in treating HMB in terms of clinical and QoL indicators.

Anti-hemorrhagic activity of Punica granatum L. flower (Persian Golnar) against heavy menstrual XXXX of endometrial origin: a double-blind, randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss', 'Blood loss'] @entity927 :: ('MESH:D014148', 'Chemical') :: ['tranexamic acid'] @entity931 :: ('MESH:D008595', 'Disease') :: ['menorrhagia'] @entity55870 :: ('MESH:C566611', 'Disease') :: ['304.92 (176.17) and 304.44 (192.72) to 164.60 (100.24) and 143.13']
@entity548 :: (MESH:D006470,Disease) :: ['bleeding']
