BACKGROUND: @entity110 ( @entity110 ) is associated with considerable burden, but data from European @entity1 are limited. METHODS: This study is a retrospective, cross-sectional analysis of National Health and Wellness Survey data from the five largest EU countries (5EU: France, Germany, Italy, Spain, and the UK) collected between 2010 and 2013. @entity66 for @entity1 with @entity110 was estimated by comparing individuals currently treated for chronic @entity110 (proxy @entity110 cases) with controls selected from respondents without chronic @entity110 . Matching and regression models were used to quantify the impact of chronic @entity110 on health-related quality of life, self-reported @entity458 , work and activity impairment, and healthcare use. RESULTS: The sample included 175,923 respondents. Prevalence of diagnosed chronic @entity110 was 0.5 and 0.2  % were treating the condition with a prescription. Cases (N  =  369) had substantially lower (worse) regression-adjusted mean Mental Component Summary (40.2 vs. 45.4), Physical Component Summary (44.6 vs. 49.9), and SF-6D health utility scores (0.63 vs. 0.71; all p  <  0.001) relative to controls (N  =  1476), differences that exceed accepted minimally important differences for these measures. @entity308 , @entity148 , and sleep difficulties were approximately twice as prevalent among those currently receiving treatment for chronic @entity110 (all p  <  0.001). Cases also had elevated presenteeism (31 vs. 17  %), @entity73 (37 vs. 20  %), and impairment in non-work activities (42 vs. 26  %; all p  <  0.01) relative to controls. Physician visits (9.1 vs. 4.9), emergency room visits (0.8 vs. 0.3), and hospitalizations (0.3 vs. 0.2) were more frequent than in controls (all p  <  0.01). CONCLUSIONS: This research adds to the existing evidence showing significant burden of @entity110 .

The Impact of Chronic Urticaria from the XXXX 's Perspective: A Survey in Five European Countries.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Depression'] @entity66 :: ('MESH:D004194', 'Disease') :: ['Burden of disease'] @entity73 :: ('MESH:D003072', 'Disease') :: ['overall work impairment'] @entity458 :: ('MESH:D020018', 'Disease') :: ['psychological complaints'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity110 :: ('MESH:D014581', 'Disease') :: ['Chronic spontaneous urticaria', 'CSU', 'urticaria']
@entity1 :: (9606,Species) :: ['Patient']
