This study was designed to document the @entity1850 ( @entity1850 ) and @entity881 ( @entity881 ) in @entity235 with complicated @entity743 , and to assess their impact on outcome. Ninety-one cases were evaluated retrospectively for @entity1850 and 56 for @entity881 . The liver, kidneys, lungs, central nervous system and musculature were assessed. Eighty-seven percent of cases were @entity1850 -positive. Fifty-two percent of the cases assessed for organ damage had single-organ damage and 48 % had @entity881 . Outcome was not significantly affected by either @entity1850 or @entity881 , but involvement of specific organs had a profound effect. Central nervous system involvement resulted in a 57 times greater chance of death and renal involvement in a 5-fold increased risk compared to all other complications. Lung involvement could not be statistically evaluated owing to co-linearity with other organs, but was associated with high mortality. Liver and @entity121 were common, but did not significantly affect outcome. There are many similarities between the observations in this study and previous @entity1 and animal studies in related fields, lending additional support to the body of evidence for shared underlying pathophysiological mechanisms in systemic inflammatory states.

@entity1850 and multiple-organ damage/dysfunction in complicated @entity235 XXXX .

@entity1 :: ('9606', 'Species') :: ['human'] @entity235 :: ('9615', 'Species') :: ['dogs'] @entity1850 :: ('MESH:D018746', 'Disease') :: ['systemic inflammatory response syndrome', 'SIRS'] @entity881 :: ('MESH:D009102', 'Disease') :: ['multiple-organ dysfunction syndrome', 'MODS'] @entity743 :: ('MESH:D001404', 'Disease') :: ['babesiosis'] @entity121 :: ('MESH:D009135', 'Disease') :: ['muscle damage']
@entity743 :: (MESH:D001404,Disease) :: ['babesiosis']
