PURPOSE: To measure anterior chamber bacterial and fungal contamination at the beginning and end of @entity231 surgery with intraocular lens (IOL) implantation in a large series of @entity1 and to determine the influence of preoperative treatment and operative technique on contamination. SETTING: Department of Ophthalmology, County Hospital of Salzburg, Austria. METHODS: This prospective study comprised 700 consecutive @entity1 having planned @entity231 extraction (511 phacoemulsification, 189 extracapsular @entity231 extraction [ECCE]). Thirty-four @entity1 required an anterior vitrectomy; 8 myopic @entity1 did not receive an IOL. A preoperative smear and two intraoperative (at the beginning and end of surgery) anterior chamber aspirates were obtained from each @entity1 . Postoperative smears were obtained at discharge. Three preoperative treatments were evaluated: no lacrimal system irrigation, no topical antibiotic (n = 282); lacrimal system irrigation with balanced saline solution, no topical antibiotic (n = 243); lacrimal system irrigation, antibiotic ( @entity5154 ) eyedrops (n = 175). All @entity1 received topical @entity3352 twice a day preoperatively. RESULTS: Preoperative conjunctival smears showed bacterial growth in 76.6% of eyes, with coagulase-negative staphylococci (75%) the most common bacteria. Anterior chamber aspirates were culture positive in 14.1% at the beginning and in 13.7% at the end of surgery, with coagulase-negative staphylococci and corynebacteria the most common. Contamination rates of conjunctival smears taken at discharge were significantly lower (35%) than those taken preoperatively. There was no statistically significantly higher risk of anterior chamber contamination in eyes having ECCE than in those having phacoemulsification. Preoperative treatment did not statistically significantly influence intraoperative aqueous humor contamination rates. There were no cases of @entity282 . CONCLUSION: Bacteria entered the anterior chamber during @entity231 extraction and remained there at the end of surgery in a significant percentage of @entity1 . Surgical technique, preoperative antibiotics, and preoperative lacrimal system irrigation had no statistically significant effect on contamination.

Anterior chamber contamination during XXXX surgery with intraocular lens implantation.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract'] @entity5154 :: ('MESH:D009355', 'Chemical') :: ['neomycin'] @entity3352 :: ('MESH:D007213', 'Chemical') :: ['indomethacin'] @entity282 :: ('MESH:D010149', 'Disease') :: ['acute postoperative endophthalmitis']
@entity231 :: (MESH:D002386,Disease) :: ['cataract']
