The @entity1062 ( @entity1062 ) is widely used in clinical practice to diagnose and distinguish @entity1 with @entity303 . It remains unclear, however, whether the @entity1062 can distinguish among the early-onset @entity303 . Accordingly, we examined the ability of both quantitative and qualitative @entity1062 analyses to distinguish @entity146 ( @entity146 ) and early-onset @entity195 (eAD), the 2 most common @entity179 with onset <65 years of age. We hypothesized that executive aspects of the @entity1062 would discriminate between these 2 disorders. The study compared 15 @entity1 with @entity146 and 16 @entity1 with eAD on the @entity1062 using 2 different scales and correlated the findings with neuropsychological testing and magnetic resonance imaging. The total @entity1062 scores did not discriminate @entity146 and eAD; however, specific analysis of executive hand placement items successfully distinguished the groups, with eAD exhibiting greater errors than @entity146 . The performance on those executive hand placement items correlated with measures of naming as well as visuospatial and executive function. On tensor-based morphometry of the magnetic resonance images, executive hand placement correlated with right frontal volume. These findings suggest that lower performance on executive hand placement items occurs with involvement of the right dorsolateral frontal-parietal network for executive control in eAD, a network disproportionately affected in @entity195 of early onset. Rather than the total performance on the clock task, the analysis of specific errors, such as executive hand placement, may be useful for early differentiation of eAD, @entity146 , and other conditions.

Executive Abilities as Reflected by Clock Hand Placement: Frontotemporal Dementia Versus Early-Onset XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity146 :: ('MESH:D001523', 'Disease') :: ['bvFTD', 'behavioral variant frontotemporal dementia'] @entity303 :: ('MESH:D003704', 'Disease') :: ['dementias', 'dementia'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative dementias'] @entity1062 :: ('MESH:D013736', 'Disease') :: ['CDT', 'clock-drawing test'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', 'Alzheimer disease']
@entity195 :: (MESH:D000544,Disease) :: ['Alzheimer Disease']
