PURPOSE: The spread of @entity14 ( @entity14 ) affects both staging and treatment. In this prospective study we examined the relationship between @entity787 ( @entity787 ) levels in bile, mesenteric venous blood, and peripheral venous blood, and the presence of occult hepatic @entity3 in @entity1 with @entity14 . METHODS: Sixty @entity1 who underwent elective surgery at Ankara Oncology Hospital were voluntarily assigned to one of the three groups of 20 @entity1 each. The control group consisted of @entity1 operated on for @entity253 , the second group consisted of @entity1 with @entity14 without @entity3 , and the third group consisted of @entity1 with @entity14 and isolated liver @entity3 . Bile, mesenteric venous blood, and peripheral venous blood was collected perioperatively for the measurement of @entity787 levels. RESULTS: The bile @entity787 levels were significantly higher in the @entity14 @entity1 with @entity3 than in those without @entity3 and the controls. The @entity787 levels in the mesenteric venous blood and peripheral venous blood were significantly higher in the two groups of @entity14 @entity1 than in the control group. Overt hepatic @entity3 later developed in seven @entity1 from the @entity14 without @entity3 group who had relatively high @entity787 levels, but the difference was not significant. CONCLUSION: The @entity787 levels in bile, mesenteric venous blood, and peripheral venous blood were increased in @entity1 with @entity14 and liver @entity3 . The detection of elevated @entity787 levels in bile taken at surgery did not herald metachronous hepatic @entity3 in @entity14 @entity1 without liver @entity3 .

@entity787 to detect hepatic XXXX of @entity14 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity787 :: ('1084', 'Gene') :: ['CEA', 'carcinoembryonic antigen'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity14 :: ('MESH:D015179', 'Disease') :: ['CRC', 'colorectal carcinoma'] @entity253 :: ('MESH:D001660', 'Disease') :: ['benign biliary disorders']
@entity3 :: (MESH:D009362,Disease) :: ['metastases']
