AIM: The optimal treatment for @entity591 remains controversial, and this study aimed to fill this gap in the knowledge. METHODS: We retrospectively reviewed all cases of @entity591 diagnosed at two tertiary foetal cardiology centres in Sweden from 1990 to 2012. RESULTS: Of the 153 cases, 28% had @entity956 ( @entity956 ), 63% had @entity2917 ( @entity2917 ) and 9% had other mechanisms. @entity4 was present in 45, less frequently in @entity956 than in @entity2917 . Transplacental treatment was commenced in 99 and the rhythm normalised in two-thirds, without any significant difference in cardioversion rates between @entity956 and @entity2917 cases or nonhydropic and hydropic foetuses. @entity2778 treatment had a higher cardioversion rate than @entity6838 in @entity2917 (63% versus 33%, p  <  0.05) but not in @entity956 (57% versus 56%). Two or more drugs were used in 38%. Neonatal survival was 100% in nonhydropic and 84% in hydropic cases. After a median of eight years, 11/134 @entity1 still had @entity943 , one had died due to @entity943 and another had undergone cardiac transplantation. CONCLUSION: Transplacental treatment was frequently insufficient to obtain cardioversion in nonhydropic and hydropic foetuses, but all nonhydropic cases had favourable outcomes. Larger prospective studies are needed to optimise the treatment of cases with @entity4 .

Foetal XXXX treatment remains challenging even if the vast majority of cases have a favourable outcome.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2917 :: ('MESH:D013611', 'Disease') :: ['AVRT', 'atrioventricular reentrant tachycardia'] @entity4 :: ('MESH:D004487', 'Disease') :: ['hydrops', 'Hydrops'] @entity591 :: ('MESH:D013610', 'Disease') :: ['foetal tachyarrhythmia'] @entity6838 :: ('MESH:D004077', 'Chemical') :: ['digoxin'] @entity956 :: ('MESH:D001282', 'Disease') :: ['atrial flutter', 'AF'] @entity2778 :: ('MESH:D013015', 'Chemical') :: ['Sotalol'] @entity943 :: ('MESH:D001145', 'Disease') :: ['arrhythmias', 'arrhythmia']
@entity591 :: (MESH:D013610,Disease) :: ['tachyarrhythmia']
