BACKGROUND: This study examined whether acutely (aMDD) and remitted @entity308 @entity1 (rMDD) @entity51 in the two aspects of social cognition - facial emotion recognition (FER) and reasoning - when using ecologically valid material. Furthermore, we examined whether reduced facial mimicry mediates the association between depressive symptoms and FER, and whether FER @entity51 are associated. METHOD: In 42 aMDD, 43 rMDD, and 39 healthy controls (HC) FER was assessed using stimuli from the Amsterdam Dynamic Facial Expression Set, reasoning by the Movie for the Assessment of Social Cognition. Furthermore, the activity of Zygomaticus Major and Corrugator supercilii were recorded. RESULTS: aMDD recognized happy faces less accurately, were less confident recognizing happiness and anger and found it more difficult to recognize happiness, anger and fear than HC. rMDD were less confident recognizing anger and found it more difficult to recognize happiness, anger and fear than HC. Reduced mimicry did not explain FER deficits. aMDD but not rMDD showed impaired reasoning. LIMITATIONS: The stimulus material was comparably easy to decode. Therefore, it is possible that the FER deficits of aMDD and rMDD @entity1 are more pronounced than demonstrated in this study. CONCLUSIONS: aMDD @entity51 in FER and reasoning, whereas rMDD only show mild impairments in the recognition of emotional expressions. There must be other processes - besides mimicry - that serve the accurate recognition of emotional facial expressions.

Facial emotion recognition, theory of mind and the role of facial mimicry in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity51 :: ('MESH:D009461', 'Disease') :: ['deficits and reasoning deficits', 'show deficits'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressed']
@entity308 :: (MESH:D003866,Disease) :: ['depression']
