UNASSIGNED: We used magnetic resonance perfusion weighted imaging and pathological evaluation to examine different stages of radiation-induced @entity1545 and to investigate the correlation between the relative cerebral blood volume (rCBV) ratio and @entity6667 ( @entity6667 ). Thirty adult @entity35 were randomly divided into 2 groups: control and radiation group. The control group was not subjected to irradiation. The irradiation group @entity35 were examined by magnetic resonance imaging and magnetic resonance perfusion weighted imaging at 1, 3, 6, 9, and 12 months after radiation treatment. We measured the rCBV, mean transit time, and time to peak. @entity1710 and @entity1711 staining, immunohistochemical staining, and electron microscopy were performed. @entity6667 absorbance was evaluated by immunohistochemical staining. Compared with the control group, the differences in rCBV, mean transit time, time to peak, and @entity6667 absorbance after 3 months were statistically significant (P < 0.05). rCBV was positively correlated with @entity6667 (r = 0.94, P < 0.05). Magnetic resonance perfusion weighted imaging can reflect pathophysiological changes in brain tissue after irradiation. Decreased expression of @entity6667 plays a critical role in the pathogenesis of radiation-induced @entity1545 .

Correlation between magnetic resonance perfusion weighted imaging of radiation XXXX and pathology.

@entity1545 :: ('MESH:D020214', 'Disease') :: ['brain injury'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['eosin'] @entity1710 :: ('MESH:D006416', 'Chemical') :: ['Hematoxylin'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity6667 :: ('83785(Tax:10116)', 'Gene') :: ['vascular endothelial growth factor', 'VEGF']
@entity1545 :: (MESH:D020214,Disease) :: ['brain injury']
