UNASSIGNED: 4172 Background: @entity420 is one of the common problems in India. Most often this is diagnosed in locoregionally advanced or in Metastatic stage.Chemotherapy is needed in most cases of ca Stomach .This study deals with @entity420 in the rural south Indian population.This is a retrospective analysis. METHODS: The diagnosis was by endoscopic biopsy. Non Metastatic ca stomach was treated with initial surgery.Chemotherapy was offered to those with Metastatic,node positive or seosa or muscle positive @entity1 The common chemotherapy protocol used was ELF ( @entity2879 100 mg/m2, @entity4181 30mg/m2,5FU 350 mg/m2 all IVF d1-d3) at three weekly interval for six cycles. RESULTS: Total of eighty @entity1 were analysed.The lesion was in70% distal, 17% proximal and 13% unknown site. In 60% the infiltration was upto serosa or beyond and in 7% upto muscle.20% had liver involvement. Nodes were involved in 44% and peritoneum was involved in 15%. 29 @entity1 had adjuvant and 51 had palliative chemotherapy. All @entity1 who had adjuvant chemo had surgery(partial gastrectomy in 69%,total gastrectomy in 24% and gastro esophagectomy in 7%).37% of @entity1 on palliative chemo had surgery like partial gastrectomy, jejunostomy or gastrojejunostomy. 59%in adjuvant and 29%in palliation were regular for treatment.31% relapsed in adjuvant group.In the palliative group56%had stable disease and 44%had progressive disease.The follow up in adjuvant group was 1-155Wks(mean 36 and median 28)and in the palliative group 1 - 52 wks(mean 11 and median 5 wks). @entity137 is grade 1 or 2 and there was no @entity137 . CONCLUSION: Chemotherapy is needed for most of these @entity1 of ca stomach. ELF protocol was simple and relatively non toxic protocol.Inspite of this a fair proportion in both adjuvant and palliative groups were not regular on treatment. The main reason is unabated symptoms of @entity5 (in palliation group) and nutritional complications of gastrectomy (in the adjuvant group). Apart from addressing superior chemotherapy, we also need to investigate areas to improve @entity1 compliance, nutritional complications of gastrectomy and quality symptom management like standard gastric diversion procedure. No significant financial relationships to disclose.

XXXX -epidemiology and treatment results of rural South Indian experience.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity4181 :: ('MESH:D002955', 'Chemical') :: ['Leucovorin'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxic death', 'Toxicity'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancy'] @entity2879 :: ('MESH:D005047', 'Chemical') :: ['Etoposide'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma of stomach', 'Adenocarcinoma of stomach']
@entity420 :: (MESH:D000230,Disease) :: ['Adenocarcinoma of stomach']
