BACKGROUND AND OBJECTIVES: The purpose of this study was to review our Japanese institutional experience of @entity5 and to compare differences in the clinical spectrum between adults and @entity1 . METHODS: We retrospectively reviewed the records of 806 @entity1 (676 adults and 130 @entity1 ) between 1951 and 2000 at our institution. RESULTS: There were 244 @entity704 (36%), 106 @entity2971 (16%), 95 @entity45 (14%), 82 @entity706 (12%), 76 @entity5 (11%), and 24 @entity259 (4%) in adult @entity1 . There were 60 @entity5 (46%), 24 germ cell @entity5 (19%), 17 @entity706 (13%), 10 @entity45 (8%), and 5 @entity704 (4%) in the pediatric @entity1 . There was a significant higher incidence of @entity5 and a lower incidence of @entity704 and @entity259 in @entity1 than adults. The most common location was the anterior compartment (68%) in adults and the posterior compartment in @entity1 (52%). The prevalence of @entity5 in pediatric @entity1 was lower than adults (37% vs. 47%; P < 0.05). Symptoms due to compression or direct invasion into adjacent structures may have caused the higher incidence of @entity1353 or respiratory distress in the pediatric group compared to the adults (15.4% vs. 4.0%; P < 0.001). There were fewer incidences of @entity4 in @entity1 compared to adults (2.6% vs. 10.7%; P < 0.02). Emergent operations were required more often in the pediatric group than the adult group. CONCLUSIONS: We demonstrated definite differences in histologic distribution, location, and symptomatology in @entity5 between adult and pediatric populations, which should be considered in the evaluation and planning of a therapeutic modality for @entity5 .

Clinical spectrum of primary XXXX : a comparison of adult and pediatric populations at a single Japanese institution.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity704 :: ('MESH:D013945', 'Disease') :: ['thymomas'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma', 'lymphomas'] @entity2971 :: ('MESH:D009373', 'Disease') :: ['germ cell tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'mediastinal tumors', 'neurogenic tumors', 'malignancy'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity4 :: ('MESH:D004487', 'Disease') :: ['facial edema'] @entity45 :: ('MESH:D010181', 'Disease') :: ['congenital cysts'] @entity259 :: ('MESH:D013964', 'Disease') :: ['thyroid tumors']
@entity5 :: (MESH:D009369,Disease) :: ['mediastinal tumors']
