BACKGROUND: It is possible that blood B vitamins level and cognitive function may be affected by dietary intake of these vitamins, no study however has yet been conducted on relationships between B vitamins intake and cognitive function among elderly population in Korea. This study examined the relationship between B vitamins intake and cognitive function among elderly in South Korea. METHODS: @entity1 consisted of 100 adults with @entity73 ( @entity73 ), 100 with @entity195 ( @entity195 ), and 121 normal subjects. Dietary intake data that included the use of dietary supplements were obtained using a 24-hour recall method by well-trained interviewers. Plasma @entity1501 and @entity2186 concentrations were analyzed by radioimmunoassay, and @entity1255 ( @entity5784 ) was assessed by a high performance liquid chromatography-fluorescence method. RESULTS: Plasma levels of @entity1501 and @entity2186 were positively correlated with B vitamins intake; and plasma Hcy was negatively correlated with total intake of @entity8728 , @entity2245 , @entity2186 and @entity1501 . In the @entity195 group, a multiple regression analysis after adjusting for covariates revealed positive relationships between @entity8728 intake and test scores for the MMSE-KC, Boston Naming, Word Fluency, Word List Memory and Constructional Recall Tests; and between @entity2245 intake and the MMSE-KC, Boston Naming, Word Fluency, Word List Memory, Word List Recognition, Constructional Recall and Constructional Praxis Tests. Positive associations were observed between @entity2186 intake and the MMSE-KC, Boston Naming, Constructional Recall and Constructional Praxis Tests, and between @entity1501 intake and the Constructional Recall Test. In the @entity73 group, @entity8728 intake was positively associated with the MMSE-KC and Boston Naming Test, @entity2245 intake was positively associated with the Boston Naming Test, and @entity1501 intake was positively associated with the MMSE-KC and Word List Memory test. No associations were observed in the normal group. CONCLUSION: These results suggested that total B vitamins intake is associated with cognitive function in cognitively impaired @entity195 and @entity73 elderly, and the association is stronger in @entity195 @entity1 .

Association between intake of B vitamins and cognitive function in elderly Koreans with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Participants'] @entity1501 :: ('MESH:D005492', 'Chemical') :: ['folate'] @entity2245 :: ('MESH:D025101', 'Chemical') :: ['vitamin B6'] @entity1255 :: ('MESH:D006710', 'Chemical') :: ['homocysteine'] @entity73 :: ('MESH:D003072', 'Disease') :: ['MCI', 'mild cognitive impairment'] @entity2186 :: ('MESH:D014805', 'Chemical') :: ['vitamin B12'] @entity5784 :: ('CHEBI:17588', 'Chemical') :: ['Hcy'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"] @entity8728 :: ('MESH:D012256', 'Chemical') :: ['vitamin B2']
@entity73 :: (MESH:D003072,Disease) :: ['cognitive impairment']
