All @entity5 of the thyroid gland in Iceland during the 36 years 1955 to 1990 were studied. In all 494 @entity259 were diagnosed during that period. A considerable increase in the reported incidence of @entity259 was noted around 1965 and a decline around 1980. These changes are mainly due to variability in incidence of @entity1377 in females. The survival rate corrected for intercurrent death was similar for both @entity1377 . During the observation period there was a decline in mortality rate for this disease. In this study we also analysed if DNA-ploidy status and S-phase fraction had an effect on the prognosis of @entity1 with @entity259 . By analysing @entity5 material from paraffin blocks we were able to evaluate the ploidy status in 424 @entity5 and S-phase value in 417 @entity5 . Univariate analysis showed that both the ploidy status and the S-phase fraction gave significant values. When taking into account known prognostic variables of @entity259 in a multivariate analysis neither the ploidy status nor the S-phase value proved significant.

[ XXXX in Iceland. Epidemiology and prognostic factors with special emphasis on the results of nuclear DNA-analysis.]

@entity5 :: ('MESH:D009369', 'Disease') :: ['malignant primary tumours', 'tumours', 'tumour'] @entity1377 :: ('MESH:D002291', 'Disease') :: ['papillary and follicular carcinomas', 'papillary carcinomas'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity259 :: ('MESH:D013964', 'Disease') :: ['thyroid cancer', 'thyroid carcinomas', 'thyroid carcinoma', 'carcinoma of the thyroid gland']
@entity259 :: (MESH:D013964,Disease) :: ['Thyroid cancer']
