OBJECTIVES: New dual antiplatelet therapies (DAPTs) have been introduced in clinical practice for @entity1 with @entity1187 ( @entity1187 ). This nationwide study investigated @entity68657 patterns over time and @entity1 characteristics associated with the various treatments in a population with @entity1187 . DESIGN: This observational cohort study linked morbidity, mortality, and medication data from Swedish national registries. RESULTS: Overall, 91% (104,012 @entity1 ) of all @entity1 admitted to the hospital with an @entity1187 (2009-2013) were alive after discharge and included in this study. Compared with 2009, in 2013 @entity1 investigated with angiography increased by 10%, @entity1 revascularized with percutaneous coronary intervention (PCI) increased by 11%, and @entity1 prescribed @entity68657 increased by 8%. Mean @entity68657 duration increased from 225 to 298 days in @entity1 investigated with angiography, and from 155 to 208 days in @entity1 who were not investigated with angiography. Furthermore, in @entity1 undergoing angiography a treatment switch from @entity1397 to @entity3077 was observed. @entity68657 with @entity3076 was used to a low extent. Approximately 10% of @entity1 initiated on @entity3076 or @entity3077 switched to @entity1397 during first year of treatment. CONCLUSION: During the study more @entity1 underwent angiography and PCI. There was an increase in the proportion of @entity1187 @entity1 receiving @entity68657 , as well as longer duration of @entity68657 in line with ESC guidelines. Among @entity68657 treated @entity1 , @entity3077 has emerged as the preferred @entity3075 antagonist in @entity1 undergoing angiography, whereas @entity1397 tended to be prescribed to @entity1 treated non-invasively.

Treatment pattern of contemporary dual antiplatelet therapies after XXXX : a Swedish nationwide population based cohort study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndrome'] @entity3076 :: ('MESH:C408153', 'Chemical') :: ['prasugrel'] @entity1397 :: ('MESH:C055162', 'Chemical') :: ['clopidogrel'] @entity3077 :: ('MESH:C503700', 'Chemical') :: ['ticagrelor'] @entity68657 :: ('MESH:C028145', 'Chemical') :: ['DAPT'] @entity3075 :: ('64805', 'Gene') :: ['P2Y12']
@entity1187 :: (MESH:D054058,Disease) :: ['acute coronary syndrome']
