OBJECTIVE: This study aimed to compare the effectiveness and complications between the retropubic and transobturator approaches for the treatment of female stress @entity322 (SUI) by conducting a systematic review. MATERIALS AND METHODS: We selected all randomized controlled trials (RCTs) that compared retropubic and transobturator sling placements for treatment of SUI. We estimated pooled odds ratios and 95% confidence intervals for intraoperative and postoperative outcomes and complications. RESULTS: Six hundred twelve studies that compared retropubic and transobturator approaches to midurethral sling placement were identified, of which 16 were included in our research. Our study was based on results from 2646 @entity1 . We performed a subgroup analysis to compare outcomes and complications between the two approaches. The evidence to support the superior approach that leads to better objective/subjective cure rate was insufficient. The transobturator approach was associated with lower risks of @entity1494 (odds ratio (OR) 0.17, 95% confidence interval (CI) 0.09-0.32), @entity1410 (OR 0.32, 95% CI 0.16-0.63), and long-term voiding dysfunction (OR 0.32, 95% CI 0.17-0.61). However, the risk of thigh/groin @entity158 seemed higher in the transobturator group (OR 2.53, 95% CI 1.72-3.72). We found no statistically significant differences in the risks of other complications between the two approaches. CONCLUSIONS: This meta-analysis shows analogical objective and subjective cure rates between the retropubic and transobturator approaches to midurethral sling placement. The transobturator approach was associated with lower risks of several complications. However, good-quality studies with long-term follow-ups are warranted for further research.

Comparison between the retropubic and transobturator approaches in the treatment of female stress XXXX : a systematic review and meta-analysis of effectiveness and complications.

@entity1 :: ('9606', 'Species') :: ['women'] @entity322 :: ('MESH:D014549', 'Disease') :: ['urinary incontinence'] @entity1494 :: ('MESH:D001745', 'Disease') :: ['bladder perforation'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['retropubic/vaginal hematoma'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity322 :: (MESH:D014549,Disease) :: ['urinary incontinence']
