PURPOSE: The purpose of this study was twofold: (1) to provide a population-based estimate of @entity521 incidence, disease stage and age distribution, and survival and mortality rates in North America; and (2) to compare these figures in the province of Quebec at a time shortly before the institution of province-wide screening with those in a population-based control group, the Greater Delaware Valley (GDV) @entity5 Registry. MATERIALS AND METHODS: In Quebec, the four major pediatric teaching hospital records were searched for @entity1 with a diagnosis of @entity521 . Tumor board registry data and information supplied to the Division of Vital Statistics were also reviewed. Birth statistics were obtained from the population registry. The GDV @entity5 Registry is a population-based registry of @entity5 covering all of Delaware and parts of New Jersey, Pennsylvania, and Maryland. Age, stage of disease, and follow-up data were obtained through December 31, 1989, with @entity5934 staging data used for all comparisons. RESULTS: One hundred thirty @entity1 with @entity521 were identified in Quebec and 165 in the GDV, in a combined population of 3,178,736 @entity1 . The annual incidence of @entity521 was 10.95/10(6) under the age of 15 years and 27.75/10(6) between the ages of 0 and 4 years. The annual mortality rate due to @entity521 was 4.89/10(6) and 9.10/10(6) for the age groups 0 to 14 and 0 to 4, respectively. The overall 10-year survival rate for the 295 cases of @entity521 was 55%. The 10-year survival rates for @entity1 with @entity5 were 88%, 90%, 63%, 21%, and 81%. There was no significant difference observed in the incidence, mortality, or survival in the two populations. CONCLUSION: These data represent the first large, population-based description of the clinical presentation and outcome of @entity1 with @entity521 in North America, with no significant differences noted between Quebec @entity1 and the GDV @entity1 .

A population-based study of XXXX incidence, survival, and mortality in North America.

@entity5 :: ('MESH:D009369', 'Disease') :: ['Pediatric Tumor', 'pediatric cancer', 'Evans stage I-IV and IVS disease'] @entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity5934 :: ('MESH:C536380', 'Disease') :: ['Evans neuroblastoma'] @entity521 :: ('MESH:D009447', 'Disease') :: ['neuroblastoma']
@entity521 :: (MESH:D009447,Disease) :: ['neuroblastoma']
