Acute @entity520 is a metabolic status defined by decreased blood pH and @entity3157 , caused by overproduction of ruminal @entity6853 . It will appear when animals ingest excessive amount of nonstructural @entity3363 with low neutral detergent fiber. Animals will show @entity8814 with hydrorumen and a typical @entity5572 complex, associated with a plethora of systemic manifestations such as @entity294 and @entity5572 , infections of the lung, the heart, and/or the kidney, and laminitis, as well as @entity16 due to both @entity39 and the direct effect of @entity6853 on neurons. In feedlots, warning signs include decrease in chewing activity, weight, and dry matter intake and increase in laminitis and @entity294 prevalence. The prognosis is quite variable. Treatment will be based on the control of systemic @entity520 and @entity2700 . Prevention is the most important tool and will require normalization of ruminal pH and microbiota. Appropriate feeding strategies are essential and involve changing the dietary composition to increase neutral detergent fiber content and greater particle size and length. Appropriate grain processing can control the fermentation rate while additives such as prebiotics or probiotics can help to stabilize the ruminal environment. Immunization against producers of @entity6853 is being explored.

Ruminal XXXX in Feedlot: From Aetiology to Prevention.

@entity5572 :: ('MESH:D008100', 'Disease') :: ['dehydration, liver abscesses', 'parakeratosis-rumenitis liver abscess'] @entity2700 :: ('MESH:D003681', 'Disease') :: ['dehydration'] @entity39 :: ('MESH:D009336', 'Disease') :: ['cerebrocortical necrosis'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic symptoms'] @entity3157 :: ('CHEBI:17544', 'Chemical') :: ['bicarbonate'] @entity8814 :: ('MESH:D015814', 'Disease') :: ['ruminal hypotony/atony'] @entity520 :: ('MESH:D000138', 'Disease') :: ['acidosis', 'ruminal acidosis'] @entity6853 :: ('CHEBI:16004', 'Chemical') :: ['D-lactate'] @entity3363 :: ('MESH:D002241', 'Chemical') :: ['carbohydrates']
@entity520 :: (MESH:D000138,Disease) :: ['Acidosis']
