BACKGROUND: @entity4789 is an inflammatory disease that develops via an auto--immune mechanism following Group A beta @entity2142 . The aim of this study was to describe the clinical presentation of and cardiac involvement in @entity4789 . MATERIAL AND METHODS: The medical records of @entity4789 @entity1 admitted to the Pediatric Cardiology Unit between January 2001 and January 2013 were reviewed. The @entity1 were divided into two groups: 53 @entity1 admitted during January 2001--January 2007 were designated as Group 1, and 140 @entity1 admitted during January 2007--January 2013 were designated as Group 2. RESULTS: A total of 193 @entity1 were evaluated, including 53 in Group 1 and 140 in Group 2. There was no statistically significant difference in age, gender and latent period between the two groups. There was, however, a statistically significant difference between the annual number of cases (p=0.001). Moreover, 35 (66%) @entity1 in Group 1 and 89 (64%) @entity1 in Group 2 were admitted during the spring or winter. The most common finding, as the major criteria in the current study, was concurrent @entity2401 and @entity625 . The most common minor finding was the presence of increased acute--phase reactants. We noted a statistically significant difference between the two groups in terms of valvular involvement. Group 2 had significantly higher frequencies of isolated aortic and @entity339 than Group 1, but the composite frequency of these was lower. CONCLUSIONS: @entity4789 continues to be prevalent in @entity233 despite the country's socio--economic improvements. We conclude that echocardiography should be performed on all of the @entity1 with suspected @entity4789 because it markedly increases the detection of @entity2401 .

XXXX : a single center experience with 193 clinical cases.

@entity4789 :: ('MESH:D012213', 'Disease') :: ['Acute rheumatic fever', 'acute rheumatic fever'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral regurgitation'] @entity625 :: ('MESH:D001168', 'Disease') :: ['arthritis'] @entity233 :: ('9103', 'Species') :: ['Turkey'] @entity2142 :: ('MESH:D006461', 'Disease') :: ['hemolytic streptococcal tonsillopharyngitis'] @entity2401 :: ('MESH:D009205', 'Disease') :: ['carditis']
@entity4789 :: (MESH:D012213,Disease) :: ['Acute rheumatic fever']
