PURPOSE: To determine if cardiopulmonary exercise testing (CPET) was useful in predicting response to exercise in @entity5 @entity1 preoperatively. A secondary aim was to explore if exercise was associated with improved postoperative outcomes. METHODS: A retrospective cohort study was performed on consecutive @entity5 @entity1 from 2012 to 2014, referred for exercise prehabilitation and had two CPET preoperatively. RESULTS: Twenty-six @entity1 were analysed. There was a significant overall increase in @entity26 uptake at anaerobic threshold (AT) from 10.4 to 11.6  ml  kg(-1)  min(-1) (  AT   =   1.2        3.0  ml  kg(-1)  min(-1) [9  %]; p   =   0.046); peak @entity26 uptake (pVO2) from 16.0 to 17.7  ml  kg(-1) min(-1) (  pVO2   =   1.7        2.4  ml  kg(-1)  min(-1) [9  %]; p   =   0.002); and pVO2/BSA from 658 to 726  ml  min(-1)  m(-2); (  pVO2/BSA   =   68        112.3  mL  min(-1)  m(2) [10  %]; p   =   0.004). Fifty percent of @entity1 were responders to exercise, defined as having >10  % increase in AT. Responders had a median increase in AT of 26  % [IQR 7  %, 45  %] with an absolute increase in AT of 2.5  ml  kg(-1)  min(-1) [IQR 1.1, 3.9] (p   =   0.002) and a median increase in pVO2 of 22  % [IQR 11.5, 32.5  %] with an absolute increase in pVO2 of 3.8  ml.kg(-1).min(-1) [IQR 2.0, 5.7] (p   <   0.001). Responders were more likely to have a lower baseline AT (9.1  ml  kg(-1)  min(-1); p   =   0.002). CONCLUSIONS: Exercise improved @entity410 prior to major @entity5 surgery. Not all @entity1 responded the same, with only 50  % of the study cohort being responders to exercise. A low AT, pVO2 and ratio of AT/pVO2 at baseline were good predictors of response to exercise, with a tendency for responders to suffer fewer @entity260 .

Structured exercise program prior to major XXXX surgery improves cardiopulmonary fitness: a retrospective cohort study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['cardiorespiratory fitness'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity260 :: ('MESH:D011183', 'Disease') :: ['major postoperative complications']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
