BACKGROUND: To assess the prognostic value of @entity4341 stress echocardiography in survivors of a first uncomplicated @entity583 . @entity1 AND METHODS: A total of 75 @entity1 (68 @entity1 , 7 @entity1 ) aged 58 years (range, 37-77) were studied 3-5 days after a first @entity583 and followed up for a mean of 10 months. @entity4341 infusion was administered at high doses: 0.56 mg/kg, adding 0.28 mg/kg if the test was still negative. Two-dimensional echocardiography was continuously recorded during infusion and the test was considered positive if a decrease in regional contractile function appeared and negative if no assynergy was observed up to 15 min after the beginning of @entity4341 administration. A wall motion score index of regional function was derived by summation of individual segment scores divided by the number of interpreted segments. This was calculated for rest and peak @entity4341 echocardiograms. Fifty of 75 @entity1 underwent coronary angiography based on clinical criteria. RESULTS: There were 31 coronary events: 4 deaths, one reinfarction, 13 @entity951 . Thirteen @entity1 underwent coronary revascularization (9 bypass and 4 angioplasty). @entity4341 echocardiography was positive in 29 @entity1 (39%) and negative in 46 @entity1 (61%). Twenty @entity1 (69%) presented coronary events in the group of positive test versus only 11 (24%) of negatives (p = 0.0001). Four @entity1 died in the positive group while none in the negative group. Sensitivity, specificity and accuracy for all @entity299 were 65, 80 and 73%, respectively. Significant variables from univariate analysis were @entity4341 stress echocardiography response, wall motion score index at peak @entity4341 , ischemic changes in ECG and treatment with two or more antianginal drugs. Multivariate analysis showed positive @entity4341 echocardiography as the only independent prognostic factor to predict @entity299 in @entity1188 @entity1 (RR = 2.56; 95% CI = 1.12-5.84). Four of 19 @entity1 with one vessel disease and 17 of 22 @entity1 with 2-3 vessel disease presented a positive @entity4341 test; whereas the test was negative in the remaining nine @entity1 with normal coronary angiography. CONCLUSION: @entity4341 stress echocardiography is a safe and feasible pharmacologic stress imaging method to stratify @entity1188 @entity1 at risk of cardiovascular events.

[Prognostic value of @entity4341 echocardiography in 1st acute uncomplicated XXXX ].

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'PATIENTS', 'men'] @entity4341 :: ('MESH:D004176', 'Chemical') :: ['dipyridamole', 'Dipyridamole'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['postmyocardial infarction'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events'] @entity583 :: ('MESH:D009203', 'Disease') :: ['acute myocardial infarction']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
