Dietary fish oils, which are rich in @entity9539 , have been reported to reduce plasma lipid levels in normolipidemic subjects. We examined the effects of fish oil in 20 @entity6308 @entity1 : 10 with @entity407 and 10 with Type V. These @entity1 were put on three diets differing primarily in @entity844 composition and fat content. The control diet contained a @entity844 mixture typical of a low-fat therapeutic diet (ratio of polyunsaturated to saturated fat, 1.4), the fish-oil diet contained @entity9539 , and the vegetable-oil diet was rich in the @entity44044 , @entity4722 . Each diet was followed for four weeks. In the Type IIb group, the fish-oil diet led to decreases in both plasma @entity165 (-27 per cent) and @entity412 (-64 per cent), as compared with the control diet. Very-low-density lipoproteins (VLDLs) were also reduced markedly. The vegetable-oil diet had much less effect. With fish oil, the Type V group had marked decreases in total @entity165 and @entity412 levels (-45 and -79 per cent, respectively). VLDL levels were dramatically lowered, as were apoprotein E levels. The vegetable-oil diet (unlike the fish-oil diet) produced a rapid and significant rise in plasma @entity412 levels. We conclude that fish oils and fish may be useful components of diets for the treatment of @entity2298 .

Reduction of plasma lipids, lipoproteins, and apoproteins by dietary fish oils in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity407 :: ('MESH:D006949', 'Disease') :: ['Type IIb hyperlipidemia'] @entity844 :: ('CHEBI:35366', 'Chemical') :: ['fatty acid'] @entity2298 :: ('MESH:D015228', 'Disease') :: ['hypertriglyceridemia'] @entity6308 :: ('MESH:D064250', 'Disease') :: ['hypertriglyceridemic'] @entity44044 :: ('CHEBI:36009', 'Chemical') :: ['omega-6 fatty acid'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity9539 :: ('MESH:D015525', 'Chemical') :: ['omega-3 fatty acids'] @entity4722 :: ('MESH:D019787', 'Chemical') :: ['linoleic acid'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity2298 :: (MESH:D015228,Disease) :: ['hypertriglyceridemia']
