@entity11278 ( @entity11278 ) are forms of necrotizing @entity631 associated with anti-glomerular basement membrane (anti-GBM) and anti-neutrophil cytoplasmic antibodies (ANCA) against the antigens proteinase-3 (anti- @entity7134 ) and myeloperoxidase (anti-MPO). @entity11278 have a course of rapid progression to @entity177 . We compared the results from the semiquantitative ELISAs for anti-GMB antibodies, @entity7134 -ANCA and MPO-ANCA and the indirect immunofluorescence technique (IIF) against a new rapid assay (30 minutes) for the same antibodies in @entity1 with clinically suspected @entity11278 . The semiquantitative ELISAs for anti-GBM antibodies and @entity7134 -ANCA and MPO-ANCA have a proven diagnostic significance in @entity1 with @entity11278 I and III. There were no significant differences between the ANCA-GBM screening test and the results from the semiquantitative ELISAs (p > 0.05). We did not find significant differences between the results for @entity7134 -ANCA and MPO-ANCA from the ANCA-GBM screening test with @entity7134 and P-ANCA IIF values (p > 0.05). We also corroborated that the ANCA-GBM screening test is a diagnostic tool for @entity11278 I and III as useful as the semiquantitative ELISAs and the @entity2391 technique. The ANCA-GBM ELISA screening test is a tool as useful as the semiquantitative ELISA against anti-GBM antibodies for diagnosis of @entity11278 I. The comparison of the screening ELISA with the IIF technique and the semiquantitative ELISAs against @entity7134 -ANCA and MPO-ANCA showed similar utility for diagnosis of @entity11278 III. The advantages of the new screening assay are that three antibodies are tested at the same time, yielding results in only 30 minutes.

[Rapid-detection GBM-ANCA ELISA. An emergency tool for the early diagnosis of type I and II rapidly progressive XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity177 :: ('MESH:D051437', 'Disease') :: ['renal failure'] @entity11278 :: ('MESH:C538458', 'Disease') :: ['RPGN', 'Rapidly progressive glomerulonephritides'] @entity2391 :: ('3456', 'Gene') :: ['IFF'] @entity7134 :: ('5657', 'Gene') :: ['C-ANCA', 'PR3'] @entity631 :: ('MESH:D005921', 'Disease') :: ['glomerulonephritis']
@entity631 :: (MESH:D005921,Disease) :: ['glomerulonephritis']
