OBJECTIVES: This study was carried out to ascertain the aetiology of exudative @entity1143 when other diagnostic investigations such as pleural fluid and sputum examination for cytology and acid fast bacilli fail to yield a definitive diagnosis and to differentiate between @entity378 and @entity5 in cases suspicious of @entity5 . METHODS: Pleuroscopic biopsies were obtained in 219 cases by Chest Physicians in the endoscopy suite using flexi-rigid fiber-optic pleuroscopes. Histological sections were stained with H_E and microscopic examination performed. Ziehl-Nielsen stain for acid fast bacilli was performed in all suspected @entity378 cases and immunohistochemistry for @entity7457 and other markers were carried out for all cases suspicious of @entity5 . RESULTS: Adequate biopsy material for interpretation was obtained in 210 (95.9%) of 219 cases. Histopathology revealed 79 (37.6%) cases were @entity378 , 64 (30.5%) were malignant (primary from lung and other sites), 62 (29.5%) were non-specific @entity32 and 5 (2.4%) were @entity3509 . A definitive diagnosis of @entity378 , @entity5 was obtained in 70.5% of cases. @entity378 was encountered in a younger age-group than @entity5 . Mean age for @entity378 @entity1 was 49 years while for malignant @entity1 was 63 years. The majority (79.6%) of @entity5 encountered were metastatic @entity2220 .

Diagnostic flex-rigid pleuroscopic biopsy of parietal pleura for exudative @entity1143 in suspected malignant and XXXX cases: a retrospective study of 219 cases.

@entity1143 :: ('MESH:D010996', 'Disease') :: ['pleural effusions'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignances', 'malignancy and empyema', 'malignancy'] @entity3509 :: ('MESH:D004653', 'Disease') :: ['empyema'] @entity378 :: ('MESH:D014376', 'Disease') :: ['Tuberculosis', 'tuberculosis'] @entity2220 :: ('MESH:C538231', 'Disease') :: ['lung adenocarcinoma'] @entity7457 :: ('7080', 'Gene') :: ['Thyroid transcription factor 1']
@entity378 :: (MESH:D014376,Disease) :: ['tuberculosis']
