Although cutaneous @entity2132 ( @entity2132 ) has been noted after autologous hematopoietic cell transplantation, intestinal involvement has not been well documented. We evaluated 197 @entity1 undergoing autologous transplantation for intestinal symptoms; the source for hematopoietic cells was marrow (n=32), peripheral blood stem cells (n=146), or both (n=19). @entity1 with persistent @entity390 , @entity391 , and @entity448 after day 20 underwent upper intestinal endoscopy and mucosal biopsy. Eight @entity1 (4.1%) had diffuse @entity4 , @entity356 , and histological evidence of @entity3621 with focal apoptosis of crypt epithelial cells-typical of the findings in acute @entity2132 . All studies for viral, fungal, or bacterial causes were negative. Two @entity1 showed evidence of @entity2132 in skin and liver, respectively. All @entity1 received 1 mg/kg/day of oral @entity229 for 10 days; symptomatic improvement often occurred within days of therapy onset. At the end of @entity228 treatment, complete resolution of symptoms was seen in all eight @entity1 . In one patient, elevated serum alkaline phosphatase levels gradually normalized over the ensuing 3-4 weeks. When followed up 3 months after treatment, all @entity1 remained symptom-free without evidence of recurrent intestinal symptoms. We concluded that recipients of autologous hematopoietic cells may develop intestinal symptoms caused by a @entity3621 that is typical of acute @entity2132 . @entity1 with this syndrome promptly responded to treatment of a short course of @entity229 . The pathogenesis of @entity1819 after autologous transplant is unknown.

@entity3621 resembling XXXX following autologous hematopoietic cell transplantation.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity1819 :: ('MESH:D013272', 'Disease') :: ['gastric epithelial damage'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity448 :: ('MESH:D000855', 'Disease') :: ['anorexia'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['corticosteroid'] @entity2132 :: ('MESH:D006086', 'Disease') :: ['graft-vs.-host disease', 'GVHD'] @entity3621 :: ('MESH:D005756', 'Disease') :: ['lymphocytic gastritis'] @entity356 :: ('MESH:D013274', 'Disease') :: ['erythema of gastric mucosa']
@entity2132 :: (MESH:D006086,Disease) :: ['graft-vs.-host disease']
