BACKGROUND: Pediatric echocardiographic nomograms for systolic/diastolic functional indices are limited by small sample size and inconsistent methodologies. Our aim was to establish pediatric nomograms for mitral valve (MV) @entity11228 ( @entity11228 ) and tissue Doppler imaging (TDI) velocities. METHODS: We performed @entity11228 /TDI measurements of MV velocities and generated models testing for linear/logarithmic/exponential/square root relationships. Heteroscedasticity was accounted for by White test or Breusch-Pagan test. Age, weight, height, heart rate (HR), and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. RESULTS: In all, 904 Caucasian Italian healthy @entity1 (age 0 days-17 years; 45.5% females; BSA 0.12-2.12m(2)) were prospectively studied. No individual variable provided equations with an acceptable coefficient of determination (R(2)) and even the inclusion of multiple variables in the model resulted in only a partial amelioration of the R(2). Higher R(2) were obtained for @entity11228 -E deceleration time (0.53), septal (Se') and lateral (Le') MV-TDI e' velocity (Se': 0.54; Le': 0.55). Variability was higher at lower age and BSA. In older @entity1 patterns were more reproducible; however, the exclusion of neonates did not substantially improve the final models. The low R(2) hampered building of z-scores and calculation of estimated percentiles. Thus normative data have been presented as observed percentile according to age for all measurements. CONCLUSIONS: We report normal ranges for @entity11228 and TDI mitral velocities derived from a large population of Caucasian @entity1 . Variability of diastolic patterns especially at lower ages needs to be taken into account.

Nomograms for mitral inflow Doppler and tissue Doppler velocities in Caucasian XXXX .

@entity1 :: ('9606', 'Species') :: ['children'] @entity11228 :: ('MESH:C535500', 'Disease') :: ['pulsed wave Doppler', 'PWD']
@entity1 :: (9606,Species) :: ['children']
