BACKGROUND: @entity273 ( @entity274 ) in exhaled air condensate is elevated in inflammatory disorders of the lower respiratory tract. It is unknown whether viral colds contribute to exhaled @entity274 . AIM: To assess exhaled @entity274 during and after a common cold. METHODS: We examined @entity274 in the breath condensate of 20 normal subjects with acute symptoms of a common cold and after recovery 2 weeks later and, similarly, in 10 subjects without @entity281 . @entity274 was measured with a fluorimetric assay. RESULTS: At the time of @entity281 exhaled @entity274 (median, ranges) was 0.20 microM (0.03-1.2 microM), and this decreased to 0.09 microM (< 0.01-0.40 microM) after recovery (p = 0.006). There was no significant difference in lung function (forced vital capacity and forced expiratory volume in 1 sec) during and after colds. In the controls, exhaled @entity274 did not change over a 2-week period. CONCLUSIONS: @entity274 in exhaled air condensate is elevated during a common cold, and returns to normal within 2 weeks of recovery in healthy subjects. Hence, symptomatic @entity1729 may act as a confounder in studies of @entity274 as a marker of chronic lower airway @entity32 .

XXXX in breath condensate during a common cold.

@entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity274 :: ('CHEBI:16240', 'Chemical') :: ['H2O2'] @entity273 :: ('MESH:D006861', 'Chemical') :: ['Hydrogen peroxide'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['upper respiratory tract infection']
@entity273 :: (MESH:D006861,Chemical) :: ['Hydrogen peroxide']
