BACKGROUND: Alaska's marine mammals compose a large portion of the diet of indigenous coastal Alaskan @entity1 . @entity38814 ( @entity38814 ) and @entity44712 ( @entity44712 ), inhabitants of the Bering and Beaufort seas along Alaska's western and northern coasts, are 2 of the most important subsistence species, serving as major food sources to the native population. OBJECTIVE: To describe an Inupiaq @entity1 with symptoms consistent with an IgE-mediated @entity5419 after ingestion of @entity38814 and @entity44712 meat. METHODS: Extracts of cooked @entity38814 and @entity44712 were prepared, lyophilized, and evaluated for protein content. @entity3208 - @entity2975 gel electrophoresis was performed for each extract, followed by transfer to @entity12142 and IgE immunoblots. Skin prick testing was conducted using reconstituted extracts of 1:10 wt/vol dilution. RESULTS: Immunoblots revealed serum specific IgE binding with the extracts of @entity38814 and @entity44712 meat. Protein bands of approximately 25, 40, 50, and 90 kDa were found in the seal meat. Protein bands of 55 and 90 kDa were found in the whale meat. Skin prick test results were positive to whale and seal extracts with appropriate positive and negative controls. Ten control subjects had negative reactions to both extracts. CONCLUSION: A @entity1 with moderate anaphylaxis to @entity38814 and @entity44712 meat demonstrated serum specific IgE by means of immunoblot and positive skin prick test results. This is the first known reported case of specific IgE to these species.

Seal and whale meat: two newly recognized XXXX .

@entity1 :: ('9606', 'Species') :: ['patient', 'boy', 'people'] @entity5419 :: ('MESH:D005512', 'Disease') :: ['food allergy'] @entity3208 :: ('MESH:D012967', 'Chemical') :: ['Sodium dodecyl sulfate'] @entity44712 :: ('39304', 'Species') :: ['bearded seals', 'Erignathus barbatus', 'bearded seal'] @entity38814 :: ('27602', 'Species') :: ['Bowhead whales', 'Balaena mysticetus', 'bowhead whale'] @entity2975 :: ('CHEBI:51135', 'Chemical') :: ['polyacrylamide'] @entity12142 :: ('CHEBI:53325', 'Chemical') :: ['nitrocellulose']
@entity5419 :: (MESH:D005512,Disease) :: ['food allergies']
