Fibrin degradation products (F.D.P.) were determined in the serum of 163 @entity1 in whom @entity43 had been suspected on palpation at gynaecological examination and who were afterwards examined by laparoscopy or subjected to laparotomy. F.D.P. were found in the serum (0.5-30 mg/100 ml) of 23 (72%) out of 32 @entity1 with @entity5 . Of 131 @entity1 with benign findings F.D.P. (traces to 2 mg/100 ml) were found in six (4.5%), and in most of these the occurrence of F.D.P. could be explained on other clinical grounds. The findings suggest that the examination of F.D.P. in suspected @entity43 may be of diagnostic value.Determination of F.D.P. in malignant ascitic fluid showed very high values, ranging between 40 and 350 mg/ 100 ml. This argues for the occurrence of F.D.P. in the blood being due to an extravascular breakdown of fibrin caused by @entity5 cells, but they may also be due to thromboplastic and fibrinolytic agents from the @entity5 entering the blood stream.

Fibrin degradation products and XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity43 :: ('MESH:D010051', 'Disease') :: ['malignant ovarian tumour', 'ovarian tumours'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignant tumours', 'tumour']
@entity43 :: (MESH:D010051,Disease) :: ['ovarian tumours']
