BACKGROUND: Many @entity1 with @entity3885 ( @entity3885 ) carry an inaccurate diagnostic label. Symptom-based questionnaires could identify @entity1 likely to need spirometry. OBJECTIVES: We prospectively tested questions derived from a comprehensive literature review and an international Delphi panel to help identify chronic @entity3885 ( @entity1030 ) in @entity1 with prior evidence of @entity3885 . METHODS: Subjects were recruited via random mailing to primary-care practices in Aberdeen, Scotland, and Denver, Colorado. @entity1 aged 40 and older reporting any prior diagnosis of @entity3885 or any respiratory medications in the past year were enrolled. @entity1 answered 54 questions covering demographics and symptoms and underwent spirometry with reversibility testing. A study diagnosis of @entity1030 was defined by fixed @entity1224 as measured by post-bronchodilator FEV(1)/FVC <0.70. We examined ability of individual questions in a multivariate framework to discriminate between @entity1 with and without the study diagnosis of @entity1030 . RESULTS: 597 @entity1 completed all investigations and proceeded to analysis. The list of 54 questions yielded 52 items for analyses, which was reduced to 19 items for entry into a multivariate regression model. Nine items had significant relationships with the study diagnosis of @entity1030 , including increased age, pack-years, worsening cough, breathing-related disability or hospitalization, worsening @entity1353 , phlegm quantity, cold going to the chest, and receipt of treatment for breathing. Individual items yielded odds ratios ranging from 0.33 to 20.7. This questionnaire demonstrated a sensitivity of 72.0 and a specificity of 82.7. CONCLUSIONS: A short, symptom-based questionnaire identifies @entity1 more likely to have @entity1030 among @entity1 with prior evidence of @entity3885 .

Symptom-based questionnaire for differentiating XXXX and asthma.

@entity1 :: ('9606', 'Species') :: ['Persons', 'patients', 'Participants', 'persons'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['OLD', 'obstructive lung disease'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['COPD'] @entity1224 :: ('MESH:D000402', 'Disease') :: ['airway obstruction']
@entity1030 :: (MESH:D029424,Disease) :: ['COPD']
