BACKGROUND: Photodynamic therapy (PDT) is a new procedure for the treatment of @entity9292 . This preliminary study was designed to investigate the safety and effectiveness of this new technique in the treatment of @entity9292 . METHODS: Ten @entity1 were treated with PDT. Intralesional @entity2518 ( @entity6053 ) 2% was directly injected into the @entity292 . The internal and external orifices were closed. After an incubation period of 2  h, the @entity292 was irradiated using an optical fibre connected to a red laser (MULTIDIODE 630 PDT, INTERmedic, Spain) operating at 1  W/cm for 3  min (180  Joules). @entity1 demographics, operation notes and complications were recorded. RESULTS: There were no complications. The average length of @entity1 follow-up was 14.9  months (range 12-20  months). We could observe primary healing in eight @entity1 (80%). Two @entity1 (20%) showed persistence of suppuration after the operation. No @entity1 reported @entity322 postoperatively. CONCLUSIONS: PDT is a potential sphincter-saving procedure that is safe, simple and minimally invasive and has a high success rate.

Photodynamic therapy for the treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'Patient'] @entity322 :: ('MESH:D014549', 'Disease') :: ['incontinence'] @entity2518 :: ('CHEBI:17549', 'Chemical') :: ['5-aminolevulinic acid'] @entity9292 :: ('MESH:D012003', 'Disease') :: ['anal fistula'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula'] @entity6053 :: ('CHEBI:27432', 'Chemical') :: ['ALA']
@entity9292 :: (MESH:D012003,Disease) :: ['complex anal fistula']
