BACKGROUND: @entity1348 ( @entity1348 ) @entity32 in @entity1 with @entity4932 ( @entity4932 ) can lead to @entity158 and malfunction of the @entity1348 . Intra-articular corticosteroid injections (IACI) have been suggested as a treatment modality against @entity1348 @entity625 -related orofacial signs and symptoms. However, knowledge of the effect-durability of these injections remains unanswered. The aim of this pilot study was to evaluate the short and long-term effects of IACI on orofacial symptoms in a prospective observational study based on pre-specified clinical examination standards. METHODS: Thirteen @entity1 with @entity4932 and @entity625 -related orofacial signs and symptoms were included in this prospective pilot study (median 17.2  years, IQR 15-18.4  years). All @entity1 received @entity1348 IACI (11 bilateral and two unilateral) due to an insufficient response to previous @entity158 -management treatments. Three standardized clinical examinations were carried out: T1 prior to treatment, T2 short-term follow-up (mean 34  days post-treatment), T3 long-term follow-up (mean 333  days post-treatment). RESULTS: Significant @entity158 reduction was observed at the short-term follow-up (T2). Resolution of @entity158 after IACI was a rare finding at T2. Generally, the @entity158 significantly worsened between T2 and T3 examinations. The reported @entity158 levels rose between T2 and T3 indicating a loss of effect of the IACI at the long-term follow-up examination (T3). Non-significant improvements in @entity1348 mobility were observed at T2 and T3. CONCLUSION: Our results suggest a palliative (not curative) effect of IACI for @entity1348 @entity625 -related orofacial symptoms in @entity1 with long-term @entity158 complaints. The short-term improvements in signs and symptoms were partly resolved at the long-term follow-up.

@entity1348 steroid injections in XXXX with @entity4932 : an observational pilot study on the long-term effect on signs and symptoms.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity625 :: ('MESH:D001168', 'Disease') :: ['arthritis'] @entity4932 :: ('MESH:D001171', 'Disease') :: ['JIA', 'juvenile idiopathic arthritis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['orofacial pain', 'pain'] @entity1348 :: ('MESH:D013706', 'Disease') :: ['Temporomandibular joint', 'TMJ']
@entity1 :: (9606,Species) :: ['patients']
