STUDY DESIGN: Retrospective study of data collected prospectively by the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP). OBJECTIVE: To determine the incidence and risk factors for development of @entity55 following @entity2649 ( @entity2649 ). SUMMARY OF BACKGROUND DATA: @entity86 has important clinical consequences for @entity1 and the healthcare system. Few studies have examined @entity55 following spinal fusion procedures. METHODS: @entity1 in the ACS-NSQIP database who underwent @entity2649 during 2005-2013 were included. The primary outcome was a diagnosis of @entity55 within the first 30 postoperative days. Independent risk factors for the development of @entity86 were identified using multivariate regression. Rates of @entity295 and mortality were compared between @entity1 who did and did not develop @entity55 using multivariate regression that adjusted for all demographic, comorbidity, and procedural characteristics. RESULTS: 12,428 @entity1 undergoing @entity2649 were identified. The incidence of @entity55 was 0.59%.Independent risk factors for the development of @entity55 were @entity1030 ( @entity1030 ) (relative risk [RR]=2.7, p=0.006), @entity479 use (RR=2.6, p=0.017), @entity2175 ( @entity6 ) (RR=2.4, p=0.003), insulin-dependent @entity6 (RR=2.9, p=0.005), and greater number of operative levels (2-level: RR=1.7, p=0.033; 3-level: RR=2.7, p=0.007). @entity1 who developed @entity55 had a higher rate of @entity295 (15.1% versus 0.8%, adjusted RR=14.5, p<0.001) and mortality (2.7% versus 0.1%, adjusted RR=27.0, p<0.001) than other @entity1 . Of all @entity295 cases and postoperative mortalities, 10.5% and 18.2% occurred in @entity1 who had developed @entity55 , respectively. CONCLUSIONS: @entity55 occurs in approximately 1/200 @entity1 following @entity2649 . @entity55 plays a significant role in the development of @entity295 and mortality, with 10% of @entity295 and 20% of mortality cases occurring in @entity1 who had developed @entity55 . @entity1 with @entity1030 , @entity479 use, @entity6 , and a greater number of operative levels are at greater risk. These @entity1 should be counseled, monitored, and targeted with preventative interventions accordingly. LEVEL OF EVIDENCE: 3.

Incidence and Risk Factors for XXXX Following Posterior Lumbar Fusion Procedures: An ACS-NSQIP Study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity2175 :: ('MESH:D003924', 'Disease') :: ['non-insulin dependent diabetes mellitus'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity6 :: ('MESH:D003920', 'Disease') :: ['DM'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia', 'Pneumonia'] @entity2649 :: ('MESH:C563613', 'Disease') :: ['posterior lumbar fusion', 'PLF'] @entity86 :: ('MESH:D019106', 'Disease') :: ['Postoperative pneumonia', 'postoperative pneumonia'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease', 'COPD'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity55 :: (MESH:D011014,Disease) :: ['Pneumonia']
