BACKGROUND: @entity426 due to lower limb central paralysis, frequently involving @entity426 , is a common cause of disability in @entity15 and has been treated with transcutaneous functional electrical stimulation (FES). We provide here the first report of 4-channel semi-implantable FES of the peroneal nerve which has been successfully used for rehabilitation in @entity1 following @entity64 . METHODS: FES was implemented via a 4-channel semi-implantable closed-loop system (ActiGait  ,   Ottobock), generating dorsiflexion in @entity426 . Walking distance, gait symmetry (temporospatial gait analyses, Vicon Motion Systems  ), gait velocity (10  m walking test) and quality of life (SF-36 questionnaire) were measured to evaluate the therapeutic benefit of this system in two @entity1 with progressive @entity15 . RESULTS: Walking distance increased from 517 to 1884  m in @entity1 1 and from 52 to 506  m in @entity1 2. Gait velocity did not change significantly in @entity1 1 and increased from 0.6 to 0.8  m/s in @entity1 2. Maximum deviations of center of mass from the midline to each side changed significantly after 3  months of stimulation compared to baseline, decreasing from 15 to 12  mm in @entity1 1 and from 47 to 37  mm in @entity1 2. Both @entity1 experienced reduced @entity158 and @entity1295 and benefits to quality of life. Adverse events did not occur during the observation period. CONCLUSION: We conclude that implantable 4-channel FES systems are not only feasible but present a promising new alternative for treating central @entity426 in @entity15 @entity1 .

Functional electrical stimulation through direct 4-channel nerve stimulation to improve gait in XXXX : a feasibility study.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity426 :: ('MESH:D020233', 'Disease') :: ['drop foot', 'Gait dysfunction'] @entity15 :: ('MESH:D009103', 'Disease') :: ['MS', 'multiple sclerosis']
@entity15 :: (MESH:D009103,Disease) :: ['multiple sclerosis']
