BACKGROUND AND AIMS: @entity1 who underwent a successful repair of the @entity1498 show chronic hyperdynamic state and normal left ventricular (LV) geometry; however, there are few data regarding the LV systolic function in the long term. Accordingly, we assessed LV systolic mechanics and factors associated with LV @entity299 (LVSD) in @entity1 with repaired @entity9931 . METHODS: Clinical and echocardiographic data from 19 repaired @entity9931 were analyzed 28        13 years after surgery. Stress-corrected midwall shortening (sc- @entity15 ) and mitral annular peak systolic velocity (S') were analyzed as indexes of LV circumferential and longitudinal systolic function, respectively. Echocardiographic data of @entity9931 @entity1 were compared with 19 @entity1 matched for age and @entity101 and 38 healthy controls. Sc- @entity15 was considered impaired if <89%, S' if <8.5 cm/s (10th percentiles of healthy controls, respectively). RESULTS: There were no statistical differences between study groups in LV volumes, mass and geometry. LV ejection fraction and Sc- @entity15 were similar in all groups, however, @entity9931 group had a significantly lower peak S' in comparison with matched and healthy controls (7.1        1.3, 10.3        1.9, and 11.1        1.5, respectively; all P   <   0.001). Prevalence of longitudinal LVSD defined as low S' was 84% in @entity9931 , 13% in matched, and 5% in healthy control group (all P<0.05). Multivariate logistic regression analysis revealed that low peak S' was independently related to higher E/E' ratio and the presence of @entity9931 . CONCLUSIONS: @entity1 who underwent a successful repair of @entity9931 commonly show asymptomatic longitudinal LVSD associated with worse LV diastolic function in the long-term follow-up.

Insights from Cardiac Mechanics after Three Decades from Successfully Repaired XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity9931 :: ('MESH:D003065', 'Chemical') :: ['CoA'] @entity1498 :: ('MESH:D001017', 'Disease') :: ['aortic coarctation'] @entity299 :: ('MESH:D006331', 'Disease') :: ['systolic dysfunction'] @entity15 :: ('MESH:D009103', 'Disease') :: ['MS']
@entity1498 :: (MESH:D001017,Disease) :: ['Aortic Coarctation']
