INTRODUCTION: @entity1201 is still one of the most frequent causes of @entity1897 . Although regarded as eradicated in Portugal, is still documented in neuropathological study of @entity1 with clinical @entity1897 without proper diagnosis. MATERIAL AND METHODS: Review of the cases of @entity16 diagnosed in Neuropathology Unit of Centro Hospitalar do Porto between 1978 and 2013, atending to gender, age, clinical manifestations and neuropathological findings. RESULTS: Twenty one @entity1 were identified with neuropathological diagnosis of @entity16 , predominantly male. The mean age at diagnosis was 52 years, and sensory symptoms predominate as neurological manifestation of disease. Interval between symptoms and diagnosis was 1-38 years. In most nerve samples tuberculoid type of disease was identified. Bacilli were detected in skin and nerve in 44% of cases. DISCUSSION: @entity4216 is the most common presentation of @entity1201 but other clinical manifestations are possible, including @entity272 . Infection with @entity4430 injures myelinated and unmyelinated fibres, with replacement of nerve tissue by collagen @entity82 . The diagnosis of @entity1201 is only achieved by neuropathological study of @entity272 and / or peripheral nerve, supported by the identification of the bacillus. CONCLUSION: @entity1201 remains a public health problem in tropical areas and, although rare, still described in Western countries reason why should still be considered as a diagnostic possibility in the investigation of @entity1897 .

XXXX : Still a Possible Diagnosis in the Investigation of a @entity1897 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity16 :: ('MESH:D009422', 'Disease') :: ['Hansen disease neuropathy', 'Hansen  s disease neuropathy'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['peripheral neuropathy'] @entity4430 :: ('1769', 'Species') :: ['M. leprae'] @entity4216 :: ('MESH:D020422', 'Disease') :: ['Mononeuritis'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesions'] @entity1201 :: ('MESH:D007918', 'Disease') :: ['Leprosy', 'leprosy', 'Hansen disease']
@entity16 :: (MESH:D009422,Disease) :: ['Hansen Neuropathy']
