@entity6795 or @entity600 due to abnormalities of cortical development are a well-recognized cause of intractable @entity410 . This study retrospectively examines the clinicopathologic features of 52 cases of extratemporal @entity6795 (from 135 total resections performed over a 16-year period). The study consists of 52 @entity1 (27 males; 25 females) who underwent extratemporal resection for @entity302 at a mean age of 15.1 years (range, 3 months to 44.1 years). @entity410 duration before surgery ranged from 7 to 372 months (mean duration, 129 months). Patterns of @entity6795 observed included diffuse architectural disorganization (n=48), neuronal cytomegaly (n=32), increased number of molecular layer neurons (n=32), balloon cells (n=19), gray matter @entity3664 (n=3), neuronal glial clustering (n=3), and pial glial neuronal tissue (n=2). Five @entity1 had @entity4607 . Coexistent @entity5 were present in five @entity1 ; including three @entity10053 , one @entity7667 , and one low-grade fibrillary @entity816 . Two @entity1 had @entity2916 . Follow-up was available in 50 @entity1 (mean follow-up, 29 months). Thirty-eight @entity1 (73%) had complete resolution or significant decrease in @entity410 frequency, 13 @entity1 (25%) had increased @entity410 or no change in @entity410 , and one @entity1 died in the postoperative period. In conclusion, (1). @entity6795 was identified in 38.5% of extratemporal resections for @entity302 ; (2). the common @entity6795 patterns observed included diffuse cortical disorganization, neuronal cytomegaly, and increased molecular layer neurons; (3). 10% of extratemporal @entity6795 was associated with @entity5 ; (4). improved @entity410 control was obtained in approximately three fourths of @entity1 after resection; and (5). @entity410 associated with @entity10067 were less successfully managed with surgery.

@entity6795 in extratemporal lobe intractable XXXX : a study of 52 cases.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures', 'Seizure'] @entity3664 :: ('MESH:C548481', 'Disease') :: ['heterotopia'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity6795 :: ('MESH:D054220', 'Disease') :: ['cortical dysplasia', 'Cortical dysplasias'] @entity2916 :: ('MESH:D014402', 'Disease') :: ['tuberous sclerosis'] @entity816 :: ('MESH:D001254', 'Disease') :: ['astrocytoma'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy'] @entity10053 :: ('MESH:D018302', 'Disease') :: ['dysembryoplastic neuroepithelial tumors'] @entity10067 :: ('MESH:C537067', 'Disease') :: ['balloon cell dysplasia'] @entity7667 :: ('MESH:D018303', 'Disease') :: ['ganglioglioma'] @entity4607 :: ('MESH:D006222', 'Disease') :: ['coexistent nodular hamartomas']
@entity302 :: (MESH:D004827,Disease) :: ['epilepsy']
