PURPOSE: To evaluate the frequency of high-risk histopathologic factors in Turkish @entity1 enucleated for @entity995 and to analyze the association between growth pattern, rosetta formation, @entity5 thickness, presence of @entity39 , @entity730 , neovascularization, rate of mitosis, and high-risk histopathologic factors. METHODS: Pathology reports of 59 eyes who had received enucleation for @entity995 were reviewed retrospectively. The histopathologic data included presence of @entity3 , @entity5151 , scleral extension, @entity5 thickness, presence of @entity39 , @entity730 , neovascularization, rosetta formation and lymphocyte infiltration, rate of mitosis, and growth pattern. RESULTS: This study included 59 eyes from 30 (50.8%) male and 29 (49.2%) female @entity1 . The mean age was 22.87      18.99  months. There were 30 (50.8%) eyes with @entity3 , 30 (50.8%) eyes with @entity5151 , and 5 (8.5%) eyes with scleral invasion. Endophytic growth pattern was seen in 27 (45.8%) eyes, exophytic growth pattern was seen in 2 (3.4%) eyes, and combined growth pattern was seen in 30 (50.8%) eyes. Exophytic growth pattern was found statistically related to @entity3 (p  =  0.00). Although @entity5 with greater thickness tended to have more @entity3 (p  =  0.02), there was no relation between @entity5 thickness and @entity5151 (p  =  0.09). CONCLUSIONS: Incidences of choroidal and @entity5151 showed similarity with other developing countries. Because of higher incidence of high-risk factors, intra-arterial chemotherapy with its targeted effect should be preferred carefully.

Evaluation of high-risk features of primary enucleation of XXXX with @entity995 in a tertiary center of a developing country in the era of intra-arterial chemotherapy.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcification'] @entity5151 :: ('MESH:D019574', 'Disease') :: ['optic nerve invasion'] @entity3 :: ('MESH:D009362', 'Disease') :: ['choroidal invasion'] @entity995 :: ('MESH:D012175', 'Disease') :: ['retinoblastoma']
@entity1 :: (9606,Species) :: ['patients']
