Background/Aims: Endoscopic placement of self-expandable metal stents (SEMSs) has emerged as a palliative treatment for malignant @entity1084 ( @entity1084 ). Although covered SEMSs can prevent @entity5 ingrowth, frequent migration of covered SEMSs may offset their advantages in preventing @entity5 ingrowth. Methods: We conducted this multicenter, single-arm, retrospective study at six tertiary referral centers to evaluate the safety and efficacy of a partially covered SEMS with an uncovered large-bore flare at the proximal end as an antimigration system in 41 @entity1 with symptomatic malignant @entity1084 . The primary outcome was clinical success, and the secondary outcomes were technical success, stent dysfunction, adverse events, and survival after stent placement. Results: The technical and clinical success rates were 100% and 95%, respectively. @entity409 occurred in 17 @entity1 (41%), including stent migration in nine (23%), @entity5 ingrowth in one (2%), and @entity5 overgrowth in four (10%). Two @entity1 (5%) developed adverse events: one @entity788 and one perforation. No procedure-related @entity204 was observed. Conclusions: A novel partially covered SEMS with a large-bore flare proximal end was safe and effective for malignant @entity1084 but failed to prevent stent migration. Further research is warranted to develop a covered SEMS with an optimal antimigration system.

A Novel Partially Covered Self-Expandable Metallic Stent with Proximal Flare in XXXX with Malignant Gastric Outlet Obstruction.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatitis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity409 :: ('MESH:D008107', 'Disease') :: ['Stent dysfunctions'] @entity1084 :: ('MESH:D017219', 'Disease') :: ['gastric outlet obstruction', 'GOO'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1 :: (9606,Species) :: ['Patients']
