OBJECTIVE: To study the prevalence of Barrett esophagus (BE) ( @entity356 ) in adolescents treated for @entity1152 ( @entity1152 ). SUMMARY OF BACKGROUND DATA: @entity1152 @entity1 are at high risk of BE. METHODS: This multicenter prospective study included @entity1152 @entity1 aged 15 to 19 years. All eligible @entity1 were proposed an @entity1729 with multistaged esophageal biopsies under general anesthesia. Histological suspicion of @entity4648 was confirmed centrally. RESULTS: One hundred twenty @entity1 [mean age, 16.5 years (  1.4)] were included; 70% had been treated for @entity354 ( @entity354 ) during infancy. At evaluation, 8% were undernourished, 41% had received antireflux surgery, and 41% presented with @entity354 symptoms, although only 28% were receiving medical treatment. @entity2910 was found at endoscopy in 34% and confirmed at histology in 67%. BE was suspected after endoscopy in 37% and was confirmed by histology for 43% of @entity1 (50 gastric and 1 intestinal @entity4648 ). No endoscopic or histological anomalies were found at the @entity254 site. BE was not significantly related to clinical symptoms. In multivariate analysis, BE was associated with @entity1152 without @entity292 (P = 0.03), previous multiple antireflux surgery (P = 0.04), esophageal dilation (P = 0.04), suspicion of BE at endoscopy (P < 0.001), and histological @entity2910 (P = 0.02). CONCLUSIONS: @entity1 with @entity1152 are at high risk of persistent @entity354 and BE. The development of BE is related to @entity354 history. Long-term systematic follow-up of the esophageal mucosa including multistaged biopsies is required, even in asymptomatic @entity1 . (NCT02495051).

Prevalence of Barrett Esophagus in Adolescents and Young Adults With XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1152 :: ('MESH:D004933', 'Disease') :: ['esophageal atresia', 'EA'] @entity2910 :: ('MESH:D004941', 'Disease') :: ['esophagitis', 'Esophagitis'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity4648 :: ('MESH:D008679', 'Disease') :: ['metaplasia'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['upper endoscopy'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastroesophageal reflux disease', 'GERD'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric and/or intestinal metaplasia']
@entity1152 :: (MESH:D004933,Disease) :: ['Esophageal Atresia']
