INTRODUCTION: Aspects of the management of @entity5 remain controversial. In the management of early T1 N0 disease, treatments are divided between amputation and a variety of @entity17904 ( @entity17904 ); local excision, laser techniques, chemotherapy and radiotherapy. We report on a retrospective series of @entity1 with @entity5 . @entity1 AND METHODS: Thirty-seven @entity1 were diagnosed between 1987-1996. All @entity1 records were retrieved. Data recorded included TNM stage, histological grade and treatment. The end-points were death, nodal progression and local recurrence. RESULTS: Median survivor follow-up of 42 months was obtained. Twenty-six @entity1 (70%) presented with T1 disease, 7 (19%) T2 and 4 (11%) T3 or T4. @entity66 was seen in 11 (30%). The mean age was 63 years. Overall, 13 penile amputations were performed, 13 underwent radiotherapy, 6 were locally excised in combination with radiotherapy and 3 underwent local excision alone. Two @entity1 were unsuitable for treatment. Of the total (37 @entity1 ) 15 have died; 12 from @entity5 . Ten have suffered disease progression and 12 remain alive with no evidence of disease. Twenty-three @entity1 presented with early T1 NO disease. They were treated with radiotherapy (12), local excision (2), combined radiotherapy and excision (2) and partial amputation (4). Outcome was not significantly related to treatment modality. Spread to the inguinal nodes or local recurrence has occurred in 10, of whom 2 have died. Only 13 (57%) appear disease-free. CONCLUSIONS: The characteristics of the @entity1 and the disease in this series are similar to published series in Europe and North America. There is significant variability in the modalities of treatment used within this series. Local recurrence and disease progression occurs in 43% of T1 N0 lesions. There would seem to be some room for improvement. International data are retrospective and inconclusive with regard to best practice. There is an urgent requirement for randomised controlled trials to improve the outcome of these @entity1 .

XXXX : a case for guidelines.

@entity5 :: ('MESH:D009369', 'Disease') :: ['penile cancer'] @entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity17904 :: ('MESH:D010409', 'Disease') :: ['penis conserving techniques', 'PCT'] @entity66 :: ('MESH:D004194', 'Disease') :: ['Inguinal nodal disease']
@entity5 :: (MESH:D009369,Disease) :: ['Penile cancer']
