Rest-stress sestamibi single photon emission computed tomography (SPECT) has sensitivity and specificity similar to those of @entity4214 201 SPECT for detection of @entity453 . However, sestamibi is not ideal agent to study @entity296 . There is not published experience in Latin American using dual isotope SPECT protocol to evaluate myocardial perfusion and viability. We studied 44 consecutive @entity1 with @entity453 , 37 of them with previous @entity583 . Coronary angiography was performed in all @entity1 . We used a 3 mCi rest T 201 SPECT followed by stress and 25 mCi sestamibi injection. Sestamibi SPECT was performed 30 minutes after exercise or 1 hour after pharmacologic stress with @entity4341 . To validate perfusion findings @entity1 returning next day for rest sestamibi injection and SPECT. Scintigraphic data were read by two blinded expert using 20 SPECT segment analysis and each segment was scored using 5 points scoring system (0 = normal, 4 = absent uptake). The segmental score agreement between rest thallium 201 and rest sestamibi and the comparison of defect reversibility percentage and non reversibility between both protocols was 90.7%. CONCLUSION: Separate acquisition dual isotope myocardial perfusion SPECT is accurate for @entity453 evaluation. It showed a good agreement with rest-stress sestamibi SPECT for assessment of rest perfusion defects and reversibility and it was a better method to evaluate @entity296 .

[Simultaneous assessment of perfusion and XXXX with 2 isotope studies (thallium at rest and sestamibi in exercise). Initial experience in Mexico and Latin America].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial viability'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity4214 :: ('MESH:D013793', 'Chemical') :: ['thallium'] @entity4341 :: ('MESH:D004176', 'Chemical') :: ['dipyridamole'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease']
@entity296 :: (MESH:D009202,Disease) :: ['myocardial viability']
