Lymph node @entity3 associated with @entity263 ( @entity263 ) has been shown to be a poor prognostic factor. The role of pelvic lymph node dissection (PLND) itself in relation to survival remains unclear, however. A Medline search was conducted to address this issue. The following conclusions were drawn. Only recently, improved survival due to completion of radical prostatectomy (RP) (compared to abandoning RP) in known or presumed lymph-node-positive @entity1 has been shown. Lymph node sampling can only be considered representative if an adequate number of nodes is removed. While several authors have suggested that a therapeutic benefit in @entity1 undergoing RP is not provided by PLND, the reliability of these studies is uncertain. Contrary to this, several studies have indicated the possibility of long-term survival even in the presence of limited lymph node @entity3 . The role and timing of initiation of adjuvant @entity342 deprivation therapy (ADT) in @entity1 who have node-positive disease after RP is controversial. Recent studies suggest that delaying ADT may not adversely impact survival.

Sense and nonsense of an extended pelvic lymph node dissection in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer', 'PCa'] @entity342 :: ('CHEBI:50113', 'Chemical') :: ['androgen'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
