Epidemiology and natural history of cervical and @entity1204 are not identical. So, the part of surgery in their prevention is different. For @entity2622 , mass screening and prevention allowed reduction of rates of incidence and mortality. Surgery concerns such intra-epithelial @entity5 . All the procedures, either destructive, either ablative, expose to failures as recurrence of @entity5 and more as @entity189 . For high grade epidermoid @entity5 , conisation is the best of ablative procedures to set up an accurate pathologic diagnosis and consequently to determine adequate therapy: conservative by conisation, total hysterectomy or extended hysterectomy and lymphadenectomy. For in situ @entity420 , removal of the whole cervix or total hysterectomy appears in numerous circumstances more safety. For @entity1204 , there is no efficacious screening nor secondary prevention procedure available. Natural history, specially pre-invasive disease, is not well known. @entity1373 is a real pre-invasive disease and evolve to @entity189 in 25%, and no more than 25% of this lesions regress under progestative therapy. Destructive procedures, biopsy-curettage and even endometrectomy under hysteroscopy don't realise and efficacious treatment of @entity1373 and prevention of @entity189 . Total hysterectomy is the only one true prevention of @entity1204 after failure of progestative therapy for @entity1 who desire be pregnant, in first place for @entity1 who don't.

[Prevention of cervical and XXXX : role of surgery].

@entity1204 :: ('MESH:D016889', 'Disease') :: ['endometrial carcinoma', 'endometrial carcinomas'] @entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['neoplasias', 'intra-epithelial neoplasia'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['Atypical hyperplasia', 'atypical hyperplasia'] @entity2622 :: ('MESH:D002583', 'Disease') :: ['cervical carcinoma'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinoma', 'invasive carcinoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma']
@entity1204 :: (MESH:D016889,Disease) :: ['endometrial cancer']
