Congenitally missing teeth of three generations of a family and the spousal influence on the @entity711 of the third generation is investigated. For clarification, a review of commonly used terms is included in the paper. Although there are a number of factors affecting the failure to develop permanent tooth buds, most researchers believe that an autosomal dominant trait is responsible for the @entity711 in this family. Many syndromes are associated with @entity711 , but none seem to be prevalent in the direct descendants of the first generation. A member of the second generation married a @entity1 with Witkop's (tooth-and-nail) syndrome. Subsequently, their @entity1 exhibits the same manifestations. A feature noted in this three generation pedigree is missing permanent first molars. This is considered rare, especially when few abnormal ectodermal findings are reported. Additional findings include an increased number of missing teeth, decreased tooth size and a prominent maxillary labial frenum. The dental treatment for @entity1 affected will likely involve a multidisciplinary approach. The treatment is particularly important since the lack of a full complement of teeth impacts the emotional and physical well-being of the individual. @entity1 who are missing permanent teeth should be screened for other ectodermal abnormalities to rule out syndromes associated with congenitally missing teeth. @entity711 is predicted to affect fifty percent of the fourth generation. It may vary in penetrance and expression.

Features of XXXX in three generations.

@entity1 :: ('9606', 'Species') :: ['patients', 'Children', 'person', 'child'] @entity711 :: ('MESH:C538049', 'Disease') :: ['Oligodontia', 'oligodontia']
@entity711 :: (MESH:C538049,Disease) :: ['oligodontia']
