OBJECTIVE: To determine the association between @entity442 ( @entity442 ) and @entity79 ( @entity79 ) in @entity1 over 65 years of age. SUBJECTS AND METHODS: Forty-one male @entity1 aged 65-88 years without a history of drug use or illness which is known to affect @entity79 were enrolled in the study. The control group consisted of 20 healthy @entity1 (19-62 years old). An immunoradiometric assay was used to measure @entity442 levels. Dual-energy X-ray absorptiometry was used to determine @entity79 at the proximal femur and lumbar spine. A detailed questionnaire was used to assess the epidemiological findings. RESULTS: The @entity1 over 65 years of age had a lower mean @entity442 level (102.04 +/- 36.65 vs. 196.62 +/- 84.86 ng/ml) and a lower mean @entity79 at the femoral neck, trochanter and intertrochanteric zones, Ward's triangle and total hip than the controls. No statistically significant association was observed in the @entity79 of the lumbar vertebrae between the @entity1 and controls. @entity442 levels were strongly and negatively correlated with age (p < 0.0001, r = -0.82). Logistic regression analysis showed that low @entity442 levels were strongly associated with @entity2331 of the total hip, femoral neck, trochanter and intertrochanteric zone. CONCLUSION: The finding shows that low serum @entity442 levels were associated with an increased risk of hip @entity2331 and, hence, at least partly responsible for the @entity2331 observed in @entity1 aged 65 years or over.

Relationship between insulin-like growth factor 1 and @entity79 in XXXX aged over 65 years.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity79 :: ('MESH:D001847', 'Disease') :: ['bone mineral density', 'BMD'] @entity2331 :: ('MESH:D001851', 'Disease') :: ['osteopenia'] @entity442 :: ('3479', 'Gene') :: ['insulin growth factor 1', 'IGF-1']
@entity1 :: (9606,Species) :: ['men']
