BACKGROUND: @entity12757 is a recognized complication of topical anesthesia with @entity12022 during transesophageal echocardiography (TEE). Though several risk factors have been described, the importance of individual factors is not known. We performed a retrospective study to identify determinants of the risk of @entity12757 . MATERIALS AND METHODS: All @entity1 who underwent TEE with @entity12022 topical anesthesia between June 2005 and June 2007 were included in this retrospective study. RESULTS: Of the 886 @entity1 who were included in the study, 140 had active @entity281 (15.8%). The incidence of @entity12757 in this group was 2.9% (vs. 0%, P < 0.001). Compared to those without @entity281 , @entity1 in the active @entity281 group were more likely to have a lower hemoglobin (P < 0.001), serum @entity2313 level (P < 0.001), glomerular filtration rate less than 60 ml/min per 1.73 m(2) (P < 0.001), higher rates of dialysis (P < 0.001), a higher incidence of @entity5 (P = 0.01), and increased use of @entity1443 and sulfa drugs (P < 0.001). However, multivariate logistic regression analysis did not identify any statistically significant covariates. CONCLUSION: In conclusion, @entity1 with an active @entity281 who undergo TEE are at a higher risk of @entity12757 . However, none of the risk factors for @entity12757 including active @entity281 reached statistical significance in the regression analysis which has to be interpreted with caution in view of the low event rate.

Infection and the risk of topical anesthetic induced clinically significant XXXX after transesophageal echocardiography.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2313 :: ('213', 'Gene') :: ['albumin'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancy'] @entity12022 :: ('MESH:D001566', 'Chemical') :: ['benzocaine'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'systemic infection'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['acetaminophen'] @entity12757 :: ('MESH:D008708', 'Disease') :: ['Methemoglobinemia', 'methemoglobinemia']
@entity12757 :: (MESH:D008708,Disease) :: ['methemoglobinemia']
