AIMS: To define the impact of transcutaneous @entity886 (TAVI) using the CoreValve prosthesis on @entity296 in a serial echocardiographic study with analysis of strain and strain rate. METHODS: In 36 @entity1 (83    6 years; EuroScore: 26    13%) with severe @entity472 scheduled for CoreValve implantation serial echocardiographic studies pre- and postintervention (within 1 month) were performed. @entity851 and three apical views were acquired. Using customized computer software which allows automatic frame-by-frame tracking of acoustic markers during the heart cycle circumferential, radial, and @entity6475 (CS, @entity9712 , and LS) and strain rate ( @entity9362 , RSR, and LSR) were calculated for each segment in a 16 segment model of the left ventricle. RESULTS: @entity6475 , systolic, and early diastolic @entity6475 rate increased significantly within 1 month after TAVI (LS from -15.8    3.6% to -17.6    3.1%; P < 0.001; LSR(S) from -1.03    0.21 s(-1) to -1.21    0.19 s(-1); P < 0.001 and LSR (E) from -1.15    0.42 s(-1) to 1.51    0.44 s(-1); P < 0.001). Circumferential strain and strain rate values remained unchanged after CoreValve implantation. @entity9712 (29.1    17.1 to 34.0    15.8%; ns), RSR (S) (1.56    0.69 to 1.91    0.87 s(-1); ns) and RSR(E) (-1.56    0.78 to -1.81    0.82 s(-1); ns) increased only nonsignificantly after TAVI. Analysis of covariance showed only chronic @entity8 to have a relevant impact on early diastolic LSR (P = 0.01). CONCLUSIONS: Mainly longitudinal mechanics respond to unloading of the left ventricle after TAVI for severe @entity472 while radial and circumferential deformation is substantially unchanged. Pacemaker implantation or onset of @entity714 after TAVI do not influence early @entity296 parameters.

Impact of transcutaneous @entity886 on XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['kidney disease'] @entity296 :: ('MESH:D009202', 'Disease') :: ['myocardial deformation'] @entity851 :: ('MESH:D006130', 'Disease') :: ['Midparasternal short-axis'] @entity714 :: ('MESH:D002037', 'Disease') :: ['left bundle brunch block'] @entity9712 :: ('MESH:D041441', 'Disease') :: ['RS'] @entity886 :: ('MESH:C563178', 'Disease') :: ['aortic valve implantation'] @entity6475 :: ('MESH:D013180', 'Disease') :: ['longitudinal strain', 'Longitudinal strain'] @entity472 :: ('MESH:D001024', 'Disease') :: ['aortic stenosis'] @entity9362 :: ('51435', 'Gene') :: ['CSR']
@entity296 :: (MESH:D009202,Disease) :: ['myocardial deformation']
