UNASSIGNED: Background and study aim: Esophageal stricture following endoscopic submucosal dissection (ESD) can be a serious complication in @entity1 with large @entity33 . This preliminary study examined the efficacy of using a @entity6886 ( @entity6987 ) sheet with fibrin glue for the prevention of @entity3332 after ESD. @entity1 and methods: A total of 15 @entity1 were enrolled. After resection, @entity6987 sheets were placed over the surgical wound. The size of the @entity33 was estimated by dividing the circumference of the esophagus into 12 parts of equal size. The occurrence of @entity3332 at 6 weeks, along with the proportion of @entity1 who had @entity6987 sheet remaining in place 1 week and 2 weeks after ESD, and the occurrence of adverse events were investigated. Results: The size of @entity33 in the 15 @entity1 were 7/12 (n=4), 8/12 (n=5), 9/12 (n=4), 10/12 (n=1) and 11/12 (n=1). Esophageal stricture occurred in 1/13 @entity1 (7.7%; two @entity1 were not included in the analysis because they had required surgical resection during the follow-up period). The @entity6987 sheet remained at 1 week after ESD in 13/15 @entity1 (86.7%) and at 2 weeks after ESD in 6/15 @entity1 (40%). No adverse events were observed. Conclusion: @entity6987 sheets may have the potential to prevent @entity3332 .

@entity6886 sheet application to prevent XXXX after endoscopic submucosal dissection for esophageal squamous cell carcinoma.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity6987 :: ('MESH:D011454', 'Chemical') :: ['PGA'] @entity3332 :: ('MESH:D004940', 'Disease') :: ['esophageal stricture'] @entity33 :: ('MESH:D052016', 'Disease') :: ['mucosal defect', 'mucosal defects'] @entity6886 :: ('CHEBI:53492', 'Chemical') :: ['polyglycolic acid']
@entity3332 :: (MESH:D004940,Disease) :: ['esophageal stricture']
