UNASSIGNED: Struma ovarii exhibiting malignant histology are uncommon, and aggressive clinical courses with initial extraovarian spread are even more rare. This report describes a case of @entity19967 with a predominant @entity189 component. A 65-yr-old, gravida 2, para 2, female presented with lower abdominal discomfort and @entity158 . She had a 12*10*7.5 cm @entity5 in the right ovary. Intraoperative diagnosis was high-grade spindle cell @entity5 . Right salpingo-oophorectomy and hysterectomy were performed. Macroscopically, the @entity5 invading the right tube was a yellowish-white solid mass with focal microcysts containing greenish liquid and focal @entity730 . The @entity5 was histologically characterized by a spindle cell and @entity3038 , and a minor component of benign-looking thyroid tissue with ossification. Immunohistochemically, the sarcomatous component was focally positive for CAM 5.2, EMA, @entity7457 , and thyroglobulin, indicating @entity189 . The @entity1 was treated with chemotherapy and is alive, yet with @entity5 , 25 mo after surgery. This is the first case of @entity19967 with a predominant component of @entity189 . This type of @entity19967 may lead to diagnostic problems, and sampling and differential diagnosis among @entity43 are important for making correct diagnoses.

XXXX With a Predominant Component of @entity189 .

@entity3038 :: ('MESH:D018316', 'Disease') :: ['pleomorphic sarcomatous component'] @entity19967 :: ('MESH:D013330', 'Disease') :: ['malignant struma ovarii'] @entity1 :: ('9606', 'Species') :: ['patient'] @entity43 :: ('MESH:D010051', 'Disease') :: ['sarcomatous ovarian tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity189 :: ('MESH:D002277', 'Disease') :: ['anaplastic carcinoma'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcification'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity7457 :: ('7080', 'Gene') :: ['thyroid transcription factor-1']
@entity19967 :: (MESH:D013330,Disease) :: ['Malignant Struma Ovarii']
