PURPOSE: @entity731 is a @entity262 and @entity453 is frequently associated with @entity3657 . As aortic and mitral @entity340 ( @entity340 ) share some etiopathogenetic mechanisms with @entity731 , we analyzed the risk profile and the echocardiographic characteristics of @entity1 admitted for first @entity1187 ( @entity1187 ) to investigate whether the presence of @entity340 could be a marker of asymptomatic hemodynamically significant peripheral @entity731 . METHODS: A total of 151 @entity1 admitted for @entity1187 without previous history of @entity65 were consecutively enrolled. The presence of @entity340 was identified by echocardiography; a @entity543 >= 50% by ultrasound identified carotid @entity455 (CarAD); an ankle-brachial index  <=0.9 or >= 1.4 identified lower extremity @entity455 (LEAD). Significant peripheral @entity731 was defined by the presence of CarAD and/or LEAD. RESULTS: Peripheral @entity731 was diagnosed in 82 (54.3%) @entity1 ; isolated CarAD in 24, isolated LEAD in 20, both diseases in 38 @entity1 . @entity340 was present in 103 (68.2%) @entity1 . By multivariate analysis, age (OR  =  1.059, 95% CI 1.007-1.113, P  =  0.025), @entity6 (OR  =  5.068, 95% CI 1.480-17.351, P  =  0.010), @entity340 (OR  =  7.422, 95% CI 2.421-22.880, P  <  0.001), and multivessel CAD (OR  =  3.317, 95% CI 1.281-8.586, P  =  0.013) were the only independent predictors of having peripheral @entity731 . C-statistic for @entity340 was not inferior to that obtained by age (0.728, 95% CI 0.649-0.797 vs. 0.800, 95% CI 0.727-0.861, P  =  0.101) and to that obtained by the combination of multivessel CAD with @entity6 (0.750; 95% CI 0.673-0.817, P  =  0.635), and, furthermore, it was higher than that obtained by @entity6 alone (0.620, 95% CI 0.538-0.698, P  =  0.036). CONCLUSION: Ruling out the presence of significant peripheral @entity731 should be routinely considered in @entity1 with @entity1187 showing @entity340 at echocardiography.

Aortic and Mitral Calcification Is Marker of Significant Carotid and Limb XXXX in @entity1 with First Acute Coronary Syndrome.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndrome'] @entity455 :: ('MESH:D014652', 'Disease') :: ['artery disease'] @entity3657 :: ('MESH:D058729', 'Disease') :: ['peripheral artery disease'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes', 'diabetes mellitus'] @entity262 :: ('MESH:D034721', 'Disease') :: ['systemic disease'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis', 'Atherosclerosis'] @entity340 :: ('MESH:D006349', 'Disease') :: ['VC', 'valvular calcification'] @entity543 :: ('MESH:D016893', 'Disease') :: ['carotid stenosis'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerosis']
