AIMS: To prospectively evaluate sinopulmonary disease in 24 @entity1 with primary @entity465 (11 with @entity45175 , nine with isolated @entity7491 , and two with common variable @entity465 ) and chronic productive cough, ascertain the usefulness of chest high resolution computed tomography (HRCT) in evaluating the progression of @entity358 , and test a therapeutic approach to chronic @entity1244 . METHODS: @entity358 were evaluated using lung function tests and HRCT (Bhalla score); chronic @entity1244 was diagnosed clinically and confirmed by flexible fibreoptic endoscopy. Sixteen @entity1 entered the three year follow up. RESULTS: Lung function testing revealed an obstruction in four @entity1 ; chest HRCT was abnormal in 16. There was a linear relation between the Bhalla score > or =4 and the number of months with cough/year over the previous two years (clinical score), and between the difference in clinical scores during follow up and in the previous two years and the difference in Bhalla score. The @entity358 did not significantly progress over a three year period. Thirteen @entity1 had chronic @entity1244 ; 6/10 @entity1 followed up were successfully treated with antibiotics plus topical therapy and two with @entity11766 with endoscopic sinus surgery. CONCLUSIONS: In @entity1 with primary @entity465 and chronic productive cough, HRCT is very useful in delineating the extent of lung damage. The correlation between Bhalla score and clinical findings and the favourable outcome of the disease suggests that in most @entity1 chest HRCT should not be repeated annually as previously suggested. Medical therapy seems to be effective in many cases of chronic @entity1244 .

@entity358 in primary XXXX with chronic productive cough.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity45175 :: ('MESH:C536020', 'Disease') :: ['agammaglobulinaemia'] @entity1244 :: ('MESH:D012852', 'Disease') :: ['sinusitis'] @entity7491 :: ('MESH:D017098', 'Disease') :: ['IgA deficiency'] @entity465 :: ('MESH:D007153', 'Disease') :: ['immunodeficiency', 'humoral immunodeficiency'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung disease', 'pulmonary lesions', 'Pulmonary abnormalities'] @entity11766 :: ('MESH:D009668', 'Disease') :: ['nasal polypoid disease']
@entity465 :: (MESH:D007153,Disease) :: ['humoral immunodeficiencies']
