Bone ultrasound measures (QUSs) can assess @entity174 risk in the elderly. We compared three QUSs and their association with nonvertebral @entity174 history in 7562 Swiss @entity1 70-80 years of age. The association between nonvertebral @entity174 was higher for heel than phalangeal QUS. INTRODUCTION: Because of the high morbidity and mortality associated with @entity3604 , it is essential to detect subjects at risk for such @entity174 with screening methods. Because quantitative bone ultrasound (QUS) discriminated subjects with @entity3604 from controls in several cross-sectional studies and predicted @entity174 in prospective studies, QUS could be more practical than DXA for screening. MATERIAL AND METHODS: This cross-sectional and retrospective multicenter (10 centers) study was performed to compare three QUSs (two heel ultrasounds: Achilles+ [GE-Lunar] and Sahara [Hologic]; the phalanges: ultrasound DBM sonic 1200 [IGEA]) for determining by logistic regression nonvertebral @entity174 odds ratio (OR) in a sample of 7562 Swiss @entity1 , 75.3 +/- 3.1 years of age. The two heel QUSs measured the broadband ultrasound attenuation (BUA) and the speed of sound (SOS). In addition, Achilles+ calculated the stiffness index (SI) and the Sahara calculated the quantitative ultrasound index (QUI) from BUA and SOS. The DBM sonic 1200 measured the amplitude-dependent SOS (AD-SOS). RESULTS: Eighty-six @entity1 had a history of a traumatic @entity173 after the age of 50, 1594 had a history of @entity174 , and 2016 had other nonvertebral @entity174 . No @entity174 history was reported by 3866 @entity1 . Discrimination for @entity173 was higher than for the other nonvertebral @entity174 . The two heel QUSs had a significantly higher discrimination power than the QUSs of the phalanges, with standardized ORs, adjusted for age and body mass index, ranging from 2.1 to 2.7 (95% CI = 1.6, 3.5) compared with 1.4 (95% CI = 1.1, 1.7) for the AD-SOS of DBM sonic 1200. CONCLUSION: This study showed a high association between heel QUS and @entity173 history in elderly Swiss @entity1 . This could justify integration of QUS among screening strategies for identifying elderly @entity1 at risk for @entity3604 .

Comparison of three bone ultrasounds for the discrimination of subjects with and without XXXX among 7562 elderly @entity1 .

@entity1 :: ('9606', 'Species') :: ['women'] @entity173 :: ('MESH:D006620', 'Disease') :: ['hip fracture'] @entity3604 :: ('MESH:D058866', 'Disease') :: ['osteoporotic fractures'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fractures', 'forearm fracture', 'fracture']
@entity3604 :: (MESH:D058866,Disease) :: ['osteoporotic fractures']
