OBJECTIVE: Obesity is an established risk factor for higher systolic ( @entity13519 ) and diastolic (DBP) blood pressure in adolescence and early adulthood, but birth size may also have a role. We analyzed the effects of adolescent and adult @entity28 and birth size on BP in the young adult. RESEARCH METHODS AND PROCEDURES: In a prospective longitudinal study, anthropometric measurements were obtained at birth on 67 @entity1 and 67 @entity1 born in Boston. Their body mass indices (BMI) and BP were recorded 17 years and 30 years later. RESULTS: For @entity1 , adolescent and early adult @entity28 appeared to be the stronger determinants of higher BP, although smaller head and chest circumferences at birth may also be related. We found some evidence of birth (ponderal index [PI] and head circumference) anthropometric influences on age 17 BP levels in @entity1 . By age 30, body mass variables were the dominant predictors of male BP levels. Female BMI at age 17 was positively correlated with birth adiposity (PI), but BMI at 30 was related only to age 17 BMI. Similarly, male BMI at 17 years was higher for those who weighed more at birth, but BMI at 30 years was again related only to age 17 BMI. DISCUSSION: We conclude that adult weight and @entity1017 are the major determinants of adult BP.

Blood pressure in adolescence and early adulthood related to XXXX and birth size.

@entity1 :: ('9606', 'Species') :: ['women', 'girls', 'boys'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity13519 :: ('8991', 'Gene') :: ['SBP'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity']
@entity28 :: (MESH:D009765,Disease) :: ['obesity']
