Few studies have examined the incidence of @entity3620 ( @entity3620 ) associated with distinct sources of @entity1355 exposure (occupational, familial, or environmental). We assessed the impact of @entity1355 exposure-global and by source-on the incidence of @entity3620 in Broni, an Italian town in which an @entity1355 cement factory once operated (1932-1993). Based on data collected by the Lombardy Mesothelioma Registry, we calculated the number of observed and expected @entity3620 cases among workers, their cohabitants, and @entity1 living in the area in 2000-2011. We identified 147 @entity3620 cases (17.45 expected), 138 pleural and nine peritoneal, attributable to exposure to @entity1355 from the factory. Thirty-eight cases had past occupational exposure at the factory (2.33 expected), numbering 32 @entity1 (26 pleural, six peritoneal) and six @entity1 (four pleural, two peritoneal). In the families of the workers, there were 37 @entity3620 cases (4.23 expected), numbering five @entity1 (all pleural) and 32 @entity1 (31 pleural, one peritoneal). Among residents in Broni or in the adjacent/surrounding towns, there were 72 cases of @entity3620 (10.89 expected), numbering 23 @entity1 and 49 @entity1 . The largest @entity3620 excess was found in the towns of Broni (48 observed, 3.68 expected) and Stradella (16 observed, 1.85 expected). This study documents the large impact of the @entity1355 cement factory, with about 130 excess @entity3620 cases in a 12-year period. The largest @entity3620 burden was among @entity1 , from non-occupational exposure. Almost half of the @entity3620 cases were attributable to environmental exposure.

Impact of an XXXX cement factory on mesothelioma incidence: Global assessment of effects of occupational, familial, and environmental exposure.

@entity1 :: ('9606', 'Species') :: ['women', 'people', 'men'] @entity3620 :: ('MESH:C562839', 'Disease') :: ['malignant mesothelioma', 'pleural MM', 'MM'] @entity1355 :: ('MESH:D001195', 'Disease') :: ['asbestos']
@entity1355 :: (MESH:D001195,Disease) :: ['asbestos']
