OBJECTIVE: To evaluate the role of intraoperative ablation as an adjunct to resection in @entity1 with recurrent @entity14 (rCLM). METHODS: All @entity1 undergoing curative-intent reoperative surgery for rCLM from 1992 to 2009 at a tertiary @entity5 center were included. Overall survival (OS) and @entity1349 ( @entity1349 ) were compared between @entity1 treated with resection alone or in combination with ablation. RESULTS: A total of 112 reoperative hepatectomies were performed, of which 16 were combined with ablation. The proportion of @entity1 treated with resection and ablation increased from 0% to 41%. @entity1 undergoing resection and ablation had a greater @entity5 burden (median, 4 vs. 1, p   <   0.0001) and higher baseline clinical risk scores (median, 3 vs. 2, p   =   0.065) than @entity1 undergoing resection alone. @entity1 undergoing resection and ablation had lower intraoperative @entity190 than @entity1 undergoing resection alone (344 vs. 877  ml, p   =   0.018). Five-year OS from the time of surgery was 48.6%. In multivariable analysis, there was no significant difference in OS or @entity1349 based on the treatment modality. CONCLUSION: In @entity1 with rCLM, the use of intraoperative ablation can extend the limits of surgical resection in @entity1 with disease that might otherwise not be amenable to complete resection.

Use of intraoperative ablation as an adjunct to surgical resection in the treatment of recurrent XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal liver metastases'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['RFS', 'recurrence-free survival']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal liver metastases']
