AIMS: To analyse @entity1 survival after the resection of lung metastases from @entity14 and specifically to verify whether presence of liver @entity3 prior to lung metastasectomy affects survival. METHODS: All @entity1 who, between 1998 and 2008, underwent lung metastasectomy due to @entity14 were included in the study. Kaplan-Meier survival analysis was performed with the log-rank test and Cox regression multivariate analysis. RESULTS: During this period, 101 metastasectomies were performed on 84 @entity1 . The median age of @entity1 was 65.4 years, and 60% of @entity1 were male. The 30-day mortality rate was 2%, and incidence of complications was 7%. The overall survival was 72 months, with 3-and 5-year survival rates of 70% and 54%, respectively. A total of 17 @entity1 (20%) had previously undergone resection of liver @entity3 . No significant differences were found in the distribution of what were supposed to be the main variables between @entity1 with and without previous hepatic metastases. Multivariate analysis identified the following statistically significant factors affecting survival: previous liver metastasectomy (p  =  0.03), @entity5 -infiltrated pulmonary lymph nodes (p  =  0.04), disease-free interval  >=   48 months (p  =  0.03), and presence of more than one lung @entity3 (p  <  0.01). In @entity1 with previous liver @entity3 , the shorter the time between primary colorectal surgery and the hepatectomy, the lower the survival rate after pulmonary metastasectomy (p  =  0.048). CONCLUSIONS: A previous history of liver @entity3 shortens survival after lung metastasectomy. The time between hepatic resection and lung metastasectomy does not affect survival; however, @entity1 with @entity409 and @entity14 have poorer survival rates than those with @entity66 .

Survival after lung metastasectomy for XXXX : importance of previous liver @entity3 as a prognostic factor.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['metachronous disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity409 :: ('MESH:D008107', 'Disease') :: ['synchronous liver metastasis'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal neoplasia', 'colorectal carcinoma', 'colorectal cancer']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal cancer']
