OBJECTIVES: The aim of this study was to investigate the dual blood supply of @entity1149 ( @entity1149 ) and its association with @entity5 subtype, size, and stage, using computed tomography perfusion (CTP). MATERIALS AND METHODS: A total of 54 @entity1 (median age, 65 years; range, 42-79 years; 15 @entity1 , 39 @entity1 ) with suspected @entity2 underwent a CTP scan of the @entity2 . Pulmonary and bronchial vasculature regions of interest were used to calculate independently CTP parameters (blood flow [BF], blood volume [BV], and mean transit time [MTT]) of the @entity5 tissue. The mean and maximum pulmonary and bronchial perfusion indexes (PImean and PImax) were calculated. The tumoral volume and the largest tumoral diameter were assessed. Differences in CTP parameters and indexes among @entity1149 subtypes, @entity5 stages and @entity5 dimensions were analyzed using non-parametric tests. RESULTS: According to biopsy, 37 @entity1 had @entity1149 (22 @entity420 [ @entity420 ], 8 @entity957 [ @entity957 ], 7 @entity152 [ @entity152 ]). The mean bronchial BF/pulmonary BF, bronchial BV/pulmonary BV, and bronchial MTT/pulmonary MTT was 41.2    30.0/36.9    24.2 mL/100 mL/min, 11.4    9.7/10.4    9.4 mL/100 mL, and 11.4    4.3/14.9    4.4 seconds, respectively. In general, higher bronchial BF than pulmonary BF was observed in @entity1149 (P = 0.014). Using a tumoral volume cutoff of 3.5 cm, a significant difference in pulmonary PImax was found (P = 0.028). There was a significantly higher mean pulmonary BF in LCCs and @entity957 compared with @entity420 (P = 0.018 and P = 0.044, respectively), whereas the mean bronchial BF was only significantly higher in LCCs compared with @entity420 (P = 0.024). Correspondingly, the PImax was significantly higher in LCCs and @entity957 than in @entity420 (P = 0.001 for both). Differences between bronchial and pulmonary PImean and PImax among T stages and Union Internationale Contre le @entity5 stages were not statistically significant (P values ranging from 0.691 to 0.753). CONCLUSIONS: The known dual blood supply of @entity1149 , which depends on @entity5 size and histological subtype, is reflected in CTP parameters, with parameters depending both on @entity5 size and histological subtype. This has to be accounted for when analyzing @entity1149 with CTP.

Assessment of Bronchial and Pulmonary Blood Supply in XXXX Subtypes Using Computed Tomography Perfusion.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Cancer'] @entity957 :: ('MESH:D002294', 'Disease') :: ['SCCs', 'squamous cell carcinomas'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small cell lung cancer'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer', 'lung tumor'] @entity152 :: ('MESH:D018287', 'Disease') :: ['LCC', 'large-cell carcinomas'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas', 'ACs']
@entity1149 :: (MESH:D002289,Disease) :: ['Non-Small Cell Lung Cancer']
