OBJECTIVES: To analyze the zonal location of @entity263 as a possible predictive feature of progression-free survival after radical prostatectomy. METHODS: @entity263 were divided into three groups according to the percentage of @entity5 volume (70% or more, 31% to 69%, and 30% or less) located in the transition zone (TZ). In a total of 307 @entity1 , 5-year progression-free probabilities were estimated for different clinical and pathologic @entity5 characteristics using the Kaplan-Meier method. With emphasis on the percentage of @entity5 volume located in the TZ, univariate and multivariate analyses were performed to calculate their prognostic significance in predicting progression-free probability. RESULTS: @entity263 with 70% or more, 31% to 69%, and 30% or less of the @entity5 volume in the TZ was found in 17.3%, 6.8%, and 75.9% of the @entity1 , respectively. @entity1 with @entity5 with 70% or more of the @entity5 volume in the TZ had a significantly (log-rank P = 0.0402) greater rate of biochemical cure than those with 30% or less (82.1% versus 66.2%). The increasing percentage of @entity5 volume located in the TZ was significantly (P = 0.0258) associated with a greater progression-free probability in univariate analysis, but did not retain independent significance (P = 0.5748) in multivariate analysis. Instead, pathologic stage (P <0.0001), lymph node involvement (P = 0.0189), and Gleason score on prostatectomy specimen (P = 0.0023) were independent prognosticators. CONCLUSIONS: The location of @entity263 in the TZ was associated with a greater overall biochemical cure rate after radical prostatectomy. However, it was not an independent prognosticator on multivariate analysis. Therefore, the knowledge about zonal location of @entity263 offers no advantage over the well-established prognostic factors in predicting disease recurrence.

Zonal location of XXXX : significance for disease-free survival after radical prostatectomy?

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer', 'tumors'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['Prostate cancers', 'prostate cancer', 'Prostate cancer']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
