INTRODUCTION: this study was conducted to ascertain the effects of resistance circuit training on epicardial adipose tissue (EAT) in @entity28 aged @entity1 . A secondary objective was to assess @entity121 induced by supervised resistance training to confirm the intervention program was effective and safe. METHODS: in the present interventional study, a total of 48 @entity28 aged @entity1 were recruited from the community. Twenty-four of them were randomly assigned to perform a 12-week resistance circuit training programme, 3-days per week. This training was circularly performed in 6 stations: arm curl, leg extension, seated row, leg curl, triceps extension and leg press. The Jamar handgrip electronic dynamometer was used to assess maximal handgrip strength of the dominant hand. Two experienced observers assessed EAT by transthoracic two-dimensional echocardiography. Lastly, serum samples were analysed using one-step sandwich assays for @entity908 kinase activity (CK) and myoglobin (MB) concentration. RESULTS: as was hypothesized, resistance training significantly reduced EAT thickness (8.4    1.0 vs. 7.3    1.3 mm; p = 0.014; d = 0.76) in the experimental group. Resistance training induced no significant changes in markers of @entity121 such as CK (181.6    36.9 vs. 194.2    37.8 U/l; p = 0.31) and MB (62.4    7.1 vs. 67.3    7.7 ng/ml; p = 0.26). No significant changes in any of the tested outcomes were found in the control group. CONCLUSION: resistance training reduced EAT in aged @entity28 @entity1 . A secondary finding was that the training program was effective and safe. While current results are promising, future studies are still required to consolidate this approach in clinical application.

A SHORT-TERM CIRCUIT RESISTANCE PROGRAMME REDUCED EPICARDIAL FAT IN OBESE AGED XXXX .

@entity1 :: ('9606', 'Species') :: ['women'] @entity908 :: ('MESH:D003401', 'Chemical') :: ['creatine'] @entity121 :: ('MESH:D009135', 'Disease') :: ['muscle damage'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese']
@entity1 :: (9606,Species) :: ['WOMEN']
