UNASSIGNED: Objective   The objective of this study was to estimate the effect of low-dose @entity117 in multiple gestations to prevent @entity1468 and small for gestational age (SGA) neonates. Methods   A systematic review and meta-analysis were performed through electronic database searches. Randomized controlled trials (RCTs) of @entity1 with multiple gestations assigned to receive @entity117 or placebo or no treatment were included. Outcomes included @entity1468 (mild and severe) and SGA neonates. Relative risks (RR) with their 95% confidence intervals (CI) were calculated. Result   Out of 6,853 citations, 6 RCTS, including 898 pregnancies, were included. We observed a significant reduction in the risk of @entity1468 (RR, 0.67; 95% CI, 0.48-0.94) and mild @entity1468 (RR, 0.44; 95% CI, 0.24-0.82) but not severe @entity1468 (RR, 1.02; 95% CI, 0.61-1.72) with low-dose @entity117 . The risk of SGA was not changed (RR, 1.09; 95% CI, 0.80-1.47). The @entity1468 was not different between @entity1 randomized before (RR, 0.86; 95% CI, 0.41-1.81) or after 16 weeks' gestation (RR, 0.64; 95% CI, 0.43-0.96) (p   =   0.50). Conclusion   There is low level of evidence supporting the use of low-dose @entity117 for the prevention of @entity1468 and SGA neonates in multiple gestations.

Prevention of Preeclampsia with XXXX in Multiple Gestations: A Systematic Review and Meta-analysis.

@entity1 :: ('9606', 'Species') :: ['women'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['preeclampsia', 'reduction of preeclampsia']
@entity117 :: (MESH:D001241,Chemical) :: ['Aspirin']
