BACKGROUND _ AIMS: Chronic @entity29 ( @entity29 ) have been associated with an abnormal mucosal response to the @entity344 . Although dietary fiber affects the @entity344 , there is limited information on the role of fiber on @entity8787 activity. We investigated factors associated with fiber consumption and whether it was associated with flares in @entity1 with @entity8787 . METHODS: We collected a completed 26-item dietary survey from 1619 @entity1 in the @entity30 Foundation of America Partners Internet cohort ( @entity30 , 1130; @entity31 /indeterminate colitis, 489). Eligible individuals were in remission based on disease activity index at baseline and completed a follow-up survey 6 months later. Fiber and whole grain consumption were categorized into quartiles and deciles. Disease flare at 6 months was defined as a disease activity index score exceeding remission cutoff values, and/or an @entity8787 -related surgical procedure or hospitalization since baseline. RESULTS: @entity1 with longer duration of disease, past history of surgery, and past @entity8787 hospitalization ate less fiber. The risks for disease flare differed by disease type. Compared with those in the lowest quartile of fiber consumption, @entity1 with @entity30 in the highest quartile were less likely to have a flare (adjusted odds ratios [OR], 0.58; 95% confidence interval [CI], 0.37-0.90). @entity1 with @entity30 who reported that they did not avoid high-fiber foods were    40% less likely to have a disease flare than those who avoided high-fiber foods (adjusted OR, 0.59; 95% CI, 0.43-0.81). There was no association between fiber intake and flares in @entity1 with @entity31 (adjusted OR, 1.82; 95% CI, 0.92-3.60). CONCLUSIONS: Intake of dietary fiber is associated with @entity146 flares in @entity1 with @entity30 , but not UC. Recommendations to limit dietary fiber should be re-evaluated.

Avoidance of Fiber Is Associated With Greater Risk of XXXX Flare in a 6-Month Period.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients', 'Participants'] @entity146 :: ('MESH:D001523', 'Disease') :: ['reduced disease'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal microbiota'] @entity29 :: ('MESH:D015212', 'Disease') :: ['IBDs', 'inflammatory bowel diseases'] @entity8787 :: ('MESH:C535541', 'Disease') :: ['IBD'] @entity30 :: ('MESH:D003424', 'Disease') :: ["Crohn's and Colitis", "Crohn's disease"]
@entity30 :: (MESH:D003424,Disease) :: ['Crohn's Disease']
