BACKGROUND: Ileocecal resection is the most commonly performed operation in @entity1 with @entity30 . @entity455 , with their associated morbidity, are the most feared risks of surgery. OBJECTIVE: This study aimed to assess the influence of a variety of putative risk factors in a homogenous group of @entity1 undergoing first or subsequent surgery for @entity30 to quantify the cumulative risk for @entity455 . DESIGN AND @entity1 : All @entity1 undergoing ileocecal or ileocolic resections for @entity30 from 2000 to 2010 were studied with the use of a prospective database. Demographics, operative details, possible risk factors, and @entity455 were recorded. @entity1 having strictureplasties, multiple resections, or subtotal colonic resections were excluded from analysis. Statistical analysis was by univariate analysis (Mann-Whitney U test) and binary logistic regression. OUTCOMES: An @entity455 was defined as a proven @entity834 , postoperative fistulation, or @entity6177 formation. RESULTS: Two hundred seven @entity1 (109 female) with a median age of 35 years (range, 13-75 years) were identified. One hundred seventy-three underwent primary @entity254 , 94 as an emergency procedure. Fifty-three had laparoscopic (5 converted) procedures. Nineteen of 173 @entity834 complication events (11%) were recorded. @entity134 usage (OR 2.67, 95% CI 1.0-7.2) and the presence of preoperative @entity733 formation (OR 3.4, 95% CI 1.2-9.8) were identified as independent predictors of @entity455 . In the absence of both @entity230 and @entity6177 , the risk of @entity532 was 6%, which increased to 14% if either risk factor was present. When both risk factors were present, complication rates reached 40%. CONCLUSION: Steroid usage and preoperative @entity733 were associated with higher rates of @entity532 following ileocolic resection for @entity195 . When both risk factors are present, it is best to avoid primary @entity254 .

Influence of risk factors on the safety of ileocolic XXXX in @entity30 surgery.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity455 :: ('MESH:D014652', 'Disease') :: ['Anastomotic-associated complications', 'anastomotic-associated complication', 'anastomotic-associated complications'] @entity834 :: ('MESH:D057868', 'Disease') :: ['anastomotic', 'anastomotic leak'] @entity6177 :: ('MESH:D018784', 'Disease') :: ['intra-abdominal abscess'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity532 :: ('MESH:D003925', 'Disease') :: ['anastomotic complications'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['Steroid'] @entity733 :: ('MESH:D000038', 'Disease') :: ['abscess'] @entity195 :: ('MESH:D000544', 'Disease') :: ["Cohn's disease"] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity30 :: ('MESH:D003424', 'Disease') :: ["Crohn's disease"]
@entity254 :: (MESH:C563598,Disease) :: ['anastomosis']
