PURPOSE: To determine whether the practice of not routinely changing ventilator circuits in @entity1 who require prolonged mechanical ventilation is associated with @entity2489 ( @entity2489 ). METHODS: @entity1 were divided into two groups, ventilator circuits were routinely changed every 7 days for the control group (39) and every 14 days for the experimental group (40) over a period of 1 yr (April 1, 2009-March 31, 2010). Pediatric @entity1 (age 17 yr or less) were not included. @entity2489 was diagnosed by the criteria of the Centers of Disease Control and Prevention (CDC). Incidence of @entity2489 and characteristics of @entity281 were evaluated. RESULTS: In the experimental group, 2 episodes of @entity55 were observed in 40 @entity1 and 1,322 ventilator days. The rate of @entity2489 was 1.5 per 1,000 ventilator days. There was 1 episode of @entity55 in 39 @entity1 and 481 ventilator days for the control group. The rate of @entity2489 was 2.1 per 1,000 ventilator days. The difference between both groups was not significant (p=.695). CONCLUSION: Extending ventilator circuit change interval from 7 days to 14 days does not increase the risk for @entity2489 .

[Ventilator-associated XXXX with circuit changes every 7 days versus every 14 days].

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity2489 :: ('MESH:D053717', 'Disease') :: ['ventilator-associated pneumonia', 'VAP'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia']
@entity55 :: (MESH:D011014,Disease) :: ['pneumonia']
