Studies were conducted from 1986 through 1993 to further define the geographic distribution and relative importance of different species of @entity14427 as a cause of @entity232 in Peru. @entity1 with a clinical diagnosis of cutaneous and/or mucosal or diffuse cutaneous @entity232 were enrolled at the Naval Medical Research Institute @entity1713 (NAMRID) Laboratory in Lima, the @entity66 Clinic at San Marcos University Daniel A. Carri  n, the Central Military Hospital, and a Ministry of Health hospital in Cusco, Peru. Clinical features, lesion aspirates, and biopsy tissue were obtained from each @entity1 . All specimens were collected and assayed separately, including multiple specimens from some of the same @entity1 for @entity14427 parasites by inoculating aliquots of either aspirates or biopsy tissue suspensions onto Senekji's blood agar medium. Stocks of @entity14427 isolates were used to prepare promastigotes to produce extracts for identifying the @entity14427 species by the cellulose @entity598 electrophoresis enzyme technique. A total of 351 isolates of @entity14427 were obtained from 350 @entity1 who were infected primarily in the low and high jungle of at least 15 different Departments of Peru. Of the 351 isolates, 79% were identified as L. (V.) braziliensis, 7% as L. (V.) guyanensis, 10% as L. (V.) peruviana, 2% as L. (V.) lainsoni, and 1.7% as L. (L.) amazonensis. The clinical form of disease varied depending on the species of @entity14427 , with L. (V.) braziliensis being associated most frequently with cutaneous, mucosal @entity1066 and mixed @entity3137 , and L. (V) peruviana, L. (V.) guyanensis, L. (V.) lainsoni with @entity75 . @entity14427 (L.) amazonensis was isolated from six @entity1 , three with @entity75 , one with @entity3137 , and two with diffuse @entity75 . Among all of the @entity232 cases, males were affected more frequently, and cases occurred among @entity1 less than 10 to more than 51 years of age. These data further defined the geographic distribution and the relative frequency of @entity14427 species associated with different clinical forms of @entity232 in Peru.

Geographic distribution and clinical description of XXXX cases in Peru.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity66 :: ('MESH:D004194', 'Disease') :: ['Tropical Disease'] @entity1713 :: ('MESH:D012163', 'Disease') :: ['Detachment'] @entity75 :: ('MESH:D001927', 'Disease') :: ['cutaneous lesions'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcers'] @entity232 :: ('MESH:D007896', 'Disease') :: ['leishmaniasis'] @entity598 :: ('CHEBI:47622', 'Chemical') :: ['acetate'] @entity14427 :: ('MESH:C536652', 'Disease') :: ['Leishmania'] @entity3137 :: ('MESH:D009059', 'Disease') :: ['cutaneous and mucosal disease', 'mucosal lesions']
@entity232 :: (MESH:D007896,Disease) :: ['leishmaniasis']
