We report a case of @entity1188 in a 22-yr-old @entity1 , with an 11-yr history of poorly controlled Type 1 @entity6 complicated by laser-treated @entity989 , macroalbuminuria and severe @entity4148 , also affected by @entity7491 , @entity12012 , @entity66 . She was admitted to our Hospital for @entity158 to the left thigh hindering her from walking. The @entity158 had appeared without @entity130 about 2 months before admission, and worsened progressively in spite of anti-inflammatory drugs. Clinical picture (localised tender mass without skin signs of @entity32 in an afebrile @entity1 ) and laboratory data (erythrocyte sedimentation rate 113 mm in 1 hr, fibrinogen 635 mg/dl) suggested the diagnosis of @entity1188 . Magnetic resonance imaging (MRI) confirmed this hypothesis showing a hyperintense area in T2-weighted sequences at adductor muscle group with enhancement after intravenous contrast. Symptoms subsided over the following 4 weeks after bed rest, analgesics, @entity117 and a good glycaemic control. The 3-month follow-up MRI showed total recovery. At hospital admission, the @entity1 presented a very poor glycaemic control ( @entity4051 c 15.5%). After discharge, she started--in order to avoid the weight gain associated with intensive insulin therapy--a daily intense isometric training, undergoing frequent hypoglycaemic episodes. In a few months, in spite of repeated laser treatment, @entity989 progressed to the proliferative stage with bilateral vitreous @entity548 and visual acuity decreased dramatically notwithstanding vitrectomy. This case confirms the association of @entity1188 with poorly controlled long-standing @entity6 with microvascular complications, suggests the possible role of autoimmunity, and underlines the risk of repeated hypoglycaemic episodes and isometric exercise in the progression of @entity989 .

XXXX associated with multiple autoimmune disorders, @entity7491 and a catastrophically poor glycaemic control: a case report.

@entity1 :: ('9606', 'Species') :: ['woman', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity4051 :: ('3039', 'Gene') :: ['HbA1'] @entity66 :: ('MESH:D004194', 'Disease') :: ['coeliac disease and polygenic familiar hypercolesterolaemia'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity548 :: ('MESH:D006470', 'Disease') :: ['haemorrhages'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity7491 :: ('MESH:D017098', 'Disease') :: ['IgA deficiency'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['diabetic muscle infarction'] @entity4148 :: ('MESH:D001342', 'Disease') :: ['autonomic neuropathy'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity989 :: ('MESH:D012164', 'Disease') :: ['retinopathy', 'pre-proliferative retinopathy'] @entity12012 :: ('MESH:C562768', 'Disease') :: ['autoimmune hypothyroidism'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity1188 :: (MESH:D007238,Disease) :: ['Diabetic muscle infarction']
