Healthy physiological systems exhibit irregular variability whereas diseased systems display decreased signal variability or greater regularity. The objective of this article is to report a case series of critically ill adults who displayed ultra @entity4365 in cardiac output (ULF-CO) that were discovered during a clinical study testing software for continuous physiological monitoring. Data were collected from 13 critically ill surgical and @entity130 @entity1 who required continuous cardiac output monitoring. Physiologic data were collected from clinical monitors. The computerized time series of cases displaying CO oscillations were manually reviewed. Ten @entity1 with @entity295 or the @entity1850 exhibited 18 episodes of ultra low-frequency periodic oscillations (ULF-CO) with frequencies ranging from 0.0028 to 0.000053 Hz (periods, 6 to 316 min). Intensive care unit mortality rate was 50%. The amplitude and @entity998 during ULF-CO ranged from 0.1-4.6 L and 3.9-14.3%, respectively. Duration of ULF-CO ranged from 4-108.1 h. ULF-CO could not be explained as a result of patterned artifact from measurement error or therapeutic intervention. ULF-CO may be a pathophysiologic marker that might serve the diagnosis, prognosis, and treatment of @entity3124 .

Report of a case series of ultra low-frequency oscillations in cardiac output in critically ill adults with @entity295 , XXXX , and multiple organ dysfunction syndrome.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity998 :: ('MESH:D002303', 'Disease') :: ['coefficient of variation of cardiac output'] @entity3124 :: ('MESH:D016638', 'Disease') :: ['critical illness'] @entity4365 :: ('MESH:C565121', 'Disease') :: ['low-frequency periodic sinusoidal oscillations'] @entity1850 :: ('MESH:D018746', 'Disease') :: ['systemic inflammatory response syndrome'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity1850 :: (MESH:D018746,Disease) :: ['systemic inflammatory response syndrome']
