OBJECTIVE: @entity1 with @entity5 were stratified into risk groups for survival based on surgicopathologic findings from a prospective study conducted by the Gynecologic Oncology Group from 1977-1984. The purpose of this study is to reassess these risk groups in @entity1 treated in an era of contemporary management. METHODS: @entity1 with @entity189 were identified from 1990-2005 for retrospective analysis. Charts were abstracted for clinical, histopathologic and surgical data, and @entity1 stratified into four risk groups for survival based on the clinical size of @entity5 and extent of lymph node @entity3 . Univariate and multivariate characteristics were evaluated and 5-year survival determined by Kaplan-Meier method. RESULTS: 175 @entity1 were identified that underwent surgical management with a median age at diagnosis of 59.9 years. Stage distribution included: I (n=89, 51%), II (n=53, 30%), III (n=29, 17%), and IV (n=4, 2%). Stratification into risk groups included: minimal (n=89, 51%), low (n=69, 40%), intermediate (n=11, 6%), and high (n=6; 3%). The survival rate was 100%, 97%, 82% and 100%, respectively, at median follow-up of 54.5 months. Comparatively, the survival rates for historic groups were 97.9%, 87.4%, 74.8% and 29.0%. Using multivariate analysis, age (p=0.04) and lymph node @entity3 (p=0.009) were predictive of survival. CONCLUSIONS: Survival among the minimal and low risk groups is preserved in spite of less radical surgery. 5-year survival rate for intermediate and high risk @entity1 also appears to be improved. This is likely a result of advancement in adjuvant chemo-radiation and a younger @entity1 population that presents with @entity1442 .

Gynecologic Oncology Group risk groups for XXXX : improvement in survival in the modern era.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'vulvar cancer'] @entity189 :: ('MESH:D002277', 'Disease') :: ['vulvar carcinoma'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['less advanced disease'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity189 :: (MESH:D002277,Disease) :: ['vulvar carcinoma']
