OBJECTIVE: The purpose of this study was to determine the correlation between high-resolution CT morphologic features of small @entity2220 and @entity5 growth patterns. MATERIALS AND METHODS: We examined high-resolution CT morphologic features of 59 small, surgically resected @entity2220 (diameter, 6-20 mm) that were detected on screening for @entity2 using low-dose helical CT. Among these @entity420 , 14 (24%) were visible and 45 (76%) were invisible on conventional chest radiography. The correlation between high-resolution CT morphologic features and @entity5 growth patterns was analyzed. RESULTS: Sixteen (94%) of 17 type A (Noguchi's classification) @entity420 appeared as nodules of pure ground-glass attenuation (high-resolution CT type I). Ten (71%) of 14 type @entity5 appeared as heterogeneous, low-attenuation nodules (type II). Seven (29%) of 24 type C @entity5 appeared as nodules with ground-glass attenuation in the periphery and a high-density central zone (type III), and 12 (50%) of 24 type C @entity5 appeared as homogeneous nodules with soft-tissue density (type IV). Among @entity5 with a replacement growth pattern, the size and CT values of type C @entity5 were larger than those of type A or type @entity5 (p < 0.05), whereas the percentage of ground-glass attenuation and retained air space in type C @entity5 was smaller than those in type A or type @entity5 (p < 0.01). All (100%) four type D @entity5 appeared to be homogeneous nodules with soft-tissue density (type IV). CONCLUSION: Small @entity2220 shown on CT exhibit four high-resolution CT patterns that corresponded to the histopathologic findings of different @entity5 growth patterns.

High-resolution CT analysis of small XXXX revealed on screening helical CT.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'B tumors', 'tumors'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity2220 :: ('MESH:C538231', 'Disease') :: ['peripheral lung adenocarcinomas'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas']
@entity2220 :: (MESH:C538231,Disease) :: ['peripheral lung adenocarcinomas']
