BACKGROUND: The purpose of this study was to examine the effects of intravenous @entity6948 on the duration of @entity1341 -induced epidural anaesthesia and level of wakefulness and the respective side-effects. METHODS: Sixty ASA I-II @entity1 were included in the study. Consecutive @entity1 were allocated to groups according to the last digit (odd/even) of their admission numbers. All @entity1 had epidural anaesthesia with @entity1341 0.5% performed by the same experienced anaesthesiologist. In the first group, the @entity1 were administered intravenous @entity6948 infusion just after the epidural block and continued during the operation, while those in the second group were administered physiologic saline infusion at the same amount and duration. RESULTS: The recovery time of sensory block was significantly longer in the first group. The bispectral index values were lower in the first group than in the second. Also, heart rate was significantly lower in Group I than in Group II. Regarding side-effects, shivering was significantly less frequent in the first group, whereas there was a significant increase in the requirement of @entity3897 in the first group as @entity6948 caused @entity1168 . CONCLUSION: Intravenous administration of @entity6948 prolonged the duration of epidural anaesthesia, provided sedation and had few side-effects.

Effects of XXXX on the duration of anaesthesia and wakefulness in @entity1341 epidural block.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1341 :: ('MESH:D002045', 'Chemical') :: ['bupivacaine'] @entity3897 :: ('MESH:D001285', 'Chemical') :: ['atropine'] @entity6948 :: ('MESH:D020927', 'Chemical') :: ['dexmedetomidine'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['bradycardia']
@entity6948 :: (MESH:D020927,Chemical) :: ['dexmedetomidine']
