BACKGROUND/PURPOSE: The aim of this study was to address the perioperative aspects of hepatoportoenterostomy ( @entity4851 ) for @entity2876 ( @entity2876 ), through the study of a 15-year, single-center experience of the management of this disease. METHODS: One hundred twenty-seven @entity1 were divided into three groups, depending on the variant of @entity4851 performed: group A (n = 53) underwent @entity4851 with external diversion of the Roux-en-Y @entity254 ; group B (n = 54) underwent @entity4851 with a long (35 to 40 cm) Roux-en-Y @entity254 , without diversion; and group C (n = 20) underwent the same kind of @entity4851 as group B, but with a modified, "super extensive" dissection of the porta @entity99 . Eleven @entity1 in group B had an intussusception type antireflux valve in the Roux-en-Y loop. The porta @entity99 of 105 @entity1 was histologically classified in types I to III and correlated with rate of postoperative bile flow and age at surgery. Liver transplantation was performed after @entity4851 in 20 @entity1 . RESULTS: Overall, biliary drainage was achieved in 72.5% of the @entity1 after @entity4851 and 26.8% of all @entity1 became @entity1087 free. Porta @entity99 type III was associated with a significantly higher rate of biliary drainage post- @entity4851 then types I and II. There was no difference in the rate of bile drainage, relative number of @entity1087 -free @entity1 , and mean number of episodes of @entity255 per year among surgical groups A, B, C. In group A, 43.7% of the @entity1 had complications related to the stoma. The actuarial survival of @entity1 who underwent @entity4851 followed by liver transplantation was 85%. CONCLUSIONS: (1) There is no correlation between type of porta hepatis and age at surgery for @entity2876 ; (2) @entity9429 is associated with higher rates of bile drainage post- @entity4851 ) @entity1 older than 16 weeks with @entity2876 should still be considered for @entity25687 ) in these older @entity1 , factors other than the type of porta hepatis, possibly the degree of @entity409 , play a role in the lower rate of bile drainage observed; (5) external diversion of the Roux-en-Y in @entity4851 is not beneficial and is detrimental because of @entity532 ; (6) an antireflux valve in the Roux-en-Y loop does not reduce the incidence of @entity255 post- @entity2750 ) Surgical reexploration does not restore biliary drainage; and (8) sequential therapy with @entity4851 followed by liver transplantation remains the treatment of choice for @entity2876 .

Management of XXXX in the liver transplantation era: a 15-year, single-center experience.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity25687 :: ('7050', 'Gene') :: ['HPE; (4'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver damage'] @entity532 :: ('MESH:D003925', 'Disease') :: ['stoma-related complications'] @entity4851 :: ('6469', 'Gene') :: ['HPE; (3', 'HPE'] @entity9429 :: ('MESH:D010382', 'Disease') :: ['type III porta hepatis'] @entity2876 :: ('MESH:D001656', 'Disease') :: ['BA', 'biliary atresia'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatitis'] @entity255 :: ('MESH:D002761', 'Disease') :: ['cholangitis'] @entity2750 :: ('5727', 'Gene') :: ['HPE; (7']
@entity2876 :: (MESH:D001656,Disease) :: ['biliary atresia']
