BACKGROUND: @entity2012 is a complex syndrome which influences the connective tissue and bone metabolism. Although the effects of excess @entity2124 on bone tissue are well known, its effect on periodontal tissue is an enigma. METHODS: A total of 23 acromegalic @entity1 (mean age 48.13    9.4 years) were included randomly in to this cross-sectional study. The control group consisted of 60 healthy (mean age 50.3    8.5) individuals. All @entity1 were examined by the same periodontist to evaluate @entity2520 status. RESULTS: We studied a group of 23 acromegalic @entity1 (11 females, 12 males) with estimated duration of disease from minimum of one year to 10 years (mean 4.52    2.9 years). The frequency of advanced @entity7278 in acromegalics was significantly lower than in the healthy group (p = 0.002). @entity1442 was 10 times more frequent in healthy population than in the acromegalics. CONCLUSIONS: Advanced @entity7278 is 10 times less frequent in acromegalics than in healthy population. @entity2012 is a disease which seems to be protective for periodontal tissue (Tab. 4, Ref. 30).

XXXX is protective for periodontal tissue - advanced @entity7278 is rare in acromegalics.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity2520 :: ('MESH:D010510', 'Disease') :: ['periodontal disease'] @entity7278 :: ('MESH:D055113', 'Disease') :: ['chronic periodontitis'] @entity2124 :: ('2688', 'Gene') :: ['growth hormone'] @entity2012 :: ('MESH:D000172', 'Disease') :: ['Acromegaly'] @entity1442 :: ('MESH:D020178', 'Disease') :: ['Advanced periodontitis']
@entity2012 :: (MESH:D000172,Disease) :: ['Acromegaly']
