OBJECTIVES: We sought to describe the effect of alterations in hip morphology with respect to worsening @entity572 in a community-based sample including African American (AA) and white @entity1 and @entity1 . METHODS: This nested case-control study defined case hips as Kellgren Lawrence grade (KLG) <3 on baseline supine pelvis radiographs and KLG >= 3 or THR for @entity571 at the 1st or 2nd follow-up visit (mean 6 and 13 years, respectively); control hips had KLG <3 at both visits, with gender/race distribution similar to cases. Hip morphology was assessed using HipMorf software (Oxford, UK). Descriptive means and standard errors were obtained from generalized estimating equation (GEE) models. Sex-stratified GEE regression models (accounting for within- @entity1 correlation), adjusted for age, race, BMI, and side were then employed. RESULTS: A total of 120 individuals (239 hips; 71 case/168 control) were included (25% male, 26% AA, mean age 62 years, BMI 30  kg/m(2)). Case hips tended to have greater baseline @entity11664 angles, smaller minimum joint space width (mJSW) and more frequent triangular index signs. Adjusted results among @entity1 revealed that higher @entity11664 angle, Gosvig ratio, and acetabular index were positively associated with case hips; coxa profunda was negatively associated. Among @entity1 , greater @entity11664 angle, smaller mJSW, protrusio acetabuli, and triangular index sign were associated with case hips. CONCLUSIONS: We confirmed an increased risk of worsening @entity572 due to baseline features of @entity85 among @entity1 and @entity1 , as well as protrusio acetabuli among @entity1 , and provide the first estimates of these measures in AAs.

Measures of hip morphology are related to development of worsening radiographic hip osteoarthritis over 6 to 13 year follow-up: the Johnston County XXXX Project.

@entity1 :: ('9606', 'Species') :: ['women', 'person', 'men'] @entity571 :: ('MESH:D010003', 'Disease') :: ['OA'] @entity572 :: ('MESH:D006617', 'Disease') :: ['hip OA'] @entity85 :: ('MESH:D009140', 'Disease') :: ['cam deformity'] @entity11664 :: ('2028', 'Gene') :: ['AP alpha']
@entity571 :: (MESH:D010003,Disease) :: ['Osteoarthritis']
