OBJECTIVES: Endoscopic surveillance of @entity1 with columnar-lined oesophagus (CLO) may identify those with @entity420 (AC). The benefits of surveillance are unproven and there is little evidence to support recommendations for precise endoscopic intervals. We sought to examine surveillance practice for CLO in the UK and the impact of endoscopic intervals on detection of @entity66 . METHODS: Eight hundred and seventeen @entity1 with CLO, registered with the UK National Barrett's Oesophagus registry and undergoing surveillance were studied. Endoscopic intervals were calculated and frequency of detection of @entity66 analysed using chi2 test of association. Factors affecting surveillance intervals were analysed using multiple linear regression. RESULTS: 94.7% of @entity1 with @entity258 ( @entity258 ), 95.0% with @entity1893 ( @entity1893 ) and 71.4% with AC were diagnosed on surveillance endoscopies. Mean endoscopic surveillance intervals varied between the centres from 1.07 to 1.63 years for nondysplastic @entity16973 ; 0.69-1.19 years for @entity258 , and 0.35-1.17 years for @entity1893 ; with overall mean surveillance intervals of 1.29, 1.01 and 0.44 years, respectively. When @entity258 was surveyed, significantly higher proportions of @entity1893 /AC were detected at intervals of 3 months or less (P=0.013). Shorter endoscopic intervals were significantly associated with the presence of oesophageal strictures (P=0.002), @entity1066 (P=0.046), increasing @entity1 age (P<0.001) and higher grade of @entity1141 surveyed (P<0.001). CONCLUSION: A variation in surveillance practice for CLO was observed throughout the UK. A large proportion of @entity66 is detected on specific surveillance endoscopies. Shorter endoscopic intervals for surveillance of @entity258 are associated with an increased detection of @entity1893 /AC.

Surveillance of Barrett's columnar-lined oesophagus in the UK: endoscopic intervals and frequency of detection of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity16973 :: ('CHEBI:29879', 'Chemical') :: ['CLO'] @entity66 :: ('MESH:D004194', 'Disease') :: ['dysplastic disease'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcers'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['HGD', 'high-grade dysplasia'] @entity258 :: ('MESH:D009800', 'Disease') :: ['LGD', 'low-grade dysplasia'] @entity420 :: ('MESH:D000230', 'Disease') :: ['early adenocarcinoma'] @entity1141 :: ('MESH:C535662', 'Disease') :: ['dysplasia']
@entity1141 :: (MESH:C535662,Disease) :: ['dysplasia']
