INTRODUCTION: Intranasal @entity3575 provides rapid and powerful @entity1337 which is particularly interesting in @entity1 without intravenous access. We propose to use it for @entity1337 in adults presenting renal colics. METHODS: A prospective study was conducted from the 2nd January to February 2013 in our emergency department. @entity1 aged up to 18 years old who presented with renal colic were included in this audit. @entity1 were excluded if they had @entity909 , @entity73 , acute or chronic nasal problems. A formal written consent was obtained from @entity1 . The research team was alerted by medical and nursing staff. A member of the research team would check with medical or nursing staff whether administration of Intra nasal (IN) @entity3575 was required. It was administered at a pre-calculated dose of 1.5 mg/kg and 50 mg/ml concentration was used. Data was prospectively collected by one of the researchers at various intervals during the @entity1 's presentation and recorded on a pre-formatted data sheet. @entity158 scores were collected at 5, 15, 30, 45 and 60 minutes following IN @entity3575 using a visual analogue scale @entity158 . Observations routinely collected for @entity1 receiving IV opiates and any adverse events were also recorded. RESULTS: 23 eligible patientswere enrolled; median age was 51,3years. 47,8% were @entity1 and the mean weight was 73 kg. Median dose of IN @entity3575 was 106  g. Two @entity1 have required morphinic @entity1337 despite having received adapted dose of IN @entity3575 . The initial @entity158 scores before IN @entity3575 were high with a median of 82,2 mm (59-100). Five minutes after IN @entity3575 administration the median @entity158 score dropped to 48mm(36-63) and achieved the lowest score of 8mm(0-22) at 30 min. @entity158 scores were significantly lower at 5 min (P < 0.001) and at all subsequent time points (P < 0.001). No side effects were recorded. CONCLUSION: Intranasal @entity3575 seems to be efficient for @entity1337 in adult @entity1 with renal colic.

Does intranasal XXXX provide efficient @entity1337 for renal colic in adults?

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'patient'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity909 :: ('MESH:D014474', 'Disease') :: ['loss of consciousness'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain'] @entity3575 :: ('MESH:D005283', 'Chemical') :: ['fentanyl']
@entity3575 :: (MESH:D005283,Chemical) :: ['fentanyl']
