PURPOSE: The present study was conducted to evaluate the patterns of recurrence and factors related to axillary or supraclavicular recurrence (ASR) and to suggest the probable indications of supraclavicular radiotherapy (SCRT) field modification for @entity0 @entity1 with  >=  10 axillary @entity1600 ( @entity1600 ) @entity3 who had received the current standard systemic management and limited-field SCRT. MATERIALS AND METHODS: We performed a retrospective study of @entity1 with @entity0 with  >=  10 axillary @entity1600 @entity3 who had received standard surgery with postoperative @entity138 , including limited SCRT (level III and supraclavicular area) and @entity3907 -based adjuvant chemotherapy (except for neoadjuvant chemotherapy), from January 2000 to June 2012. ASR was defined as recurrence to levels I to III of the axillary or supraclavicular area. RESULTS: The present study included 301 @entity1 with @entity0 with  >=  10 axillary @entity1600 @entity3 . The median follow-up period was 59.1 months (range, 7.4-167.9 months). Overall, 32 cases (10.6%) of locoregional recurrence were observed, and 27 @entity1 (9.0%) exhibited ASR. Additionally, 16 @entity1 (5.3%) developed recurrence in levels I or II of the axillary area, which are not included in the SCRT field. ASR-free survival was significantly related to the @entity1600 ratio (LNR) in both univariate and multivariate analysis. CONCLUSION: ASR was the most prevalent locoregional recurrence pattern in @entity1 with @entity0 with  >=  10 axillary @entity1600 @entity3 , and LNR was a significant prognostic factor for the development of ASR. Modification of the SCRT field, including the full axilla, should be considered in @entity1 with a greater LNR.

Limited Supraclavicular Radiation Field in XXXX With  >=  10 Positive Axillary Lymph Nodes.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity138 :: ('MESH:C563738', 'Disease') :: ['RT'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['LN', 'lymph node'] @entity3907 :: ('MESH:C080625', 'Chemical') :: ['taxane'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Cancer']
