OBJECTIVES: To assess the association between plasma @entity1255 ( @entity5784 ), blood pressure (BP) and poor outcome at hospital discharge among acute @entity385 @entity1 , and if high @entity5784 increases the risk of poor outcome based on high BP status in a northern Chinese population. METHODS: Between June 1, 2009 and May 31, 2013, a total of 3695 acute @entity385 @entity1 were recruited from three hospitals in northern Chinese cities. Demographic characteristics, lifestyle risk factors, medical history, and other clinical characteristics were recorded for all subjects. Poor outcome was defined as a discharge modified Rankin Scale (mRS) score >= 3 or @entity204 . The association between @entity1255 concentration, admission blood pressure, and risk of poor outcome following acute @entity385 was analyzed by using multivariate non-conditional logistic regression models. RESULTS: Compared with those in the lowest quartile of @entity5784 concentration in a multivariate-adjusted model, those in the highest quartile of @entity5784 concentration had increased risk of poor outcome after acute @entity385 , (OR=1.33, P<0.05). The dose-response relationship between @entity5784 concentration and risk of poor outcome was statistically significant (p-value for trend =0.027). High BP was significantly associated with poor outcome following acute @entity385 (adjusted OR=1.44, 95%CI, 1.19-1.74). Compared with non-high BP with nhHcy, in a multivariate-adjusted model, the ORs (95% CI) of non-high BP with hHcy, high BP with nhHcy, and high BP with hHcy to poor outcome were 1.14 (0.85-1.53), 1.37 (1.03-1.84) and 1.70 (1.29-2.34), respectively. CONCLUSION: The present study suggested that high plasma @entity5784 and blood pressure were independent risk factors for prognosis of acute @entity385 , and hHcy may further increase the risk of poor outcome among @entity1 with @entity101 . Additionally, the results indicate that high @entity5784 with high BP may cause increased susceptibility to poor outcome among acute @entity385 @entity1 in a northern Chinese population.

High XXXX and blood pressure related to poor outcome of acute ischemia stroke in chinese population.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['high blood pressure'] @entity1255 :: ('MESH:D006710', 'Chemical') :: ['homocysteine'] @entity5784 :: ('CHEBI:17588', 'Chemical') :: ['Hcy'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity1255 :: (MESH:D006710,Chemical) :: ['homocysteine']
