Mimicking the architecture of the extracellular matrix is an effective strategy for tissue engineering. Composite nanofibers similar to natural bone structure can be prepared via an electrospinning technique and used in biomedical applications. Stem cells from @entity1 exfoliated deciduous teeth (SHEDs) can differentiate into multiple cell lineages, such as cells that are alternative sources of stem cells for tissue engineering. @entity9756 has important functions in bone remodeling; for example, this element can simulate bone formation and decrease bone resorption. Incorporating @entity68524 into nanofibers provides a potential material for bone tissue engineering. This study investigated the potential of @entity4351 ( @entity4351 ) nanofibers coated or blended with @entity68524 for the osteogenic differentiation of SHEDs. Cellular morphology and @entity98 assay revealed that nanofibers effectively support cellular attachment, spreading, and proliferation. @entity9756 -loaded @entity4351 nanofibers exhibited higher expressions of collagen type I, alkaline phosphatase, biomineralization, and bone-related genes than pure @entity4351 nanofibers during the osteogenic differentiation of SHEDs. This study demonstrated that @entity9756 can be an effective inducer of osteogenesis for SHEDs. Understanding the function of bioceramics (such as @entity9756 ) is useful in designing and developing strategies for bone tissue engineering.

Osteogenic differentiation of stem cells from @entity1 exfoliated deciduous teeth on @entity4351 nanofibers containing XXXX .

@entity1 :: ('9606', 'Species') :: ['human'] @entity4351 :: ('CHEBI:60736', 'Chemical') :: ['poly(  -caprolactone)', 'PCL'] @entity98 :: ('CHEBI:53233', 'Chemical') :: ['MTT'] @entity9756 :: ('MESH:D013324', 'Chemical') :: ['Strontium', 'strontium'] @entity68524 :: ('MESH:C052774', 'Chemical') :: ['strontium phosphate']
@entity68524 :: (MESH:C052774,Chemical) :: ['strontium phosphate']
