BACKGROUND: Extracorporeal membrane oxygenation (ECMO) has a significant role as a final rescue modality in severe @entity1576 of the newborn with @entity2914 ( @entity2914 ). The objective of this study was to compare the efficiency of venovenous (VV) versus venoarterial (VA) ECMO in newborns with @entity2914 . METHODS: A retrospective report of 11 years experience (1990 through 2001) of a single center, comparing VV and VA ECMO is given. VV ECMO was the preferred rescue modality for @entity1576 unresponsive to maximal medical therapy. Only when the placement of a VV ECMO 14F catheter was not possible, VA ECMO was used. Forty-six @entity1 met ECMO criteria; 26 were treated with VV ECMO and 19 with VA ECMO. One @entity1 underwent conversion from VV to VA ECMO. RESULTS: Before ECMO, there was no difference between VV and VA ECMO @entity1 in mean oxygenation index (83 v 83), mean airway pressure (18.4 v 18.9 cm @entity2507 ), ECMO cannulation age (28 v 20 hours), or in the percentage of @entity1 who needed @entity935 and @entity452 (100% v 100%). From November 1994, @entity842 (NO) was available; before ECMO, 11 of 14 (79%) VV ECMO @entity1 received NO versus 9 of 10 (90%) @entity1 in the VA group. VV ECMO @entity1 were larger (3.34 v 2.77 kg; P <.05) and of advanced gestational age (39.0 v 36.9 wk; P <.05) compared with VA ECMO @entity1 . There was no significant difference between VV and VA ECMO @entity1 in survival rate (18 of 26, 69% v 13 of 19, 68%), ECMO duration (152 v 150 hours), time of extubation (32.0 v 33.5 days), age at discharge (73 v 81 days), or incidence of short-term intracranial complications (3.8% v 10.5%) or myocardial stun (3.8% v 15.8%). CONCLUSIONS: The authors conclude that VV ECMO is as reliable as VA ECMO in newborns with @entity2914 in severe @entity1576 who need ECMO support and who can accommodate the VV double-lumen catheter. Because of its potential advantages, VV ECMO may be the preferred ECMO method in these @entity1 .

Venovenous versus venoarterial extracorporeal membrane oxygenation in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'infants'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['dobutamine'] @entity935 :: ('MESH:D004298', 'Chemical') :: ['dopamine'] @entity2914 :: ('MESH:D065630', 'Disease') :: ['congenital diaphragmatic hernia', 'CDH'] @entity2507 :: ('CHEBI:33813', 'Chemical') :: ['H(2)O'] @entity842 :: ('MESH:D009569', 'Chemical') :: ['nitric oxide'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory failure']
@entity2914 :: (MESH:D065630,Disease) :: ['congenital diaphragmatic hernia']
