SETTING: The ELISA test is generally accepted for serodiagnosis of @entity378 . Its sensitivity and specificity depend on the antigen used and data are not always concordant. In some @entity1 suspected of @entity378 , @entity370 or @entity2 , bronchoalveolar lavage (BAL) is performed. BAL fluid (BALF) contains immunoglobulins--their source is transudation from the serum but local IgG synthesis of IgG is not excluded. OBJECTIVE: The comparison of BALF versus serum in the serodiagnosis of @entity1907 , and its differentiation from @entity370 and @entity2 . DESIGN: The IgG against A60 and 38 kDa antigens in serum and BALF were measured using the commercially available IgG EIA kits. The study included 13 @entity378 @entity1 , 8 @entity1 with @entity370 , 10 @entity1 with @entity2 and 9 healthy volunteers. RESULTS: In the serum studies the sensitivity of the assays did not exceed 40% and 60% in the estimation of IgG 38 kDa and IgG A60, respectively. The specificity of both assays was similar: 81% (IgG 38 kDa) and 69-75% (IgG A60). In BALF studies the sensitivity of the IgG 38 kDa assay was 50% and its specificity was 44%. The ranges of the IgG A60 concentrations in BALF were similar in all subject groups. CONCLUSION: In differentiation between @entity378 , @entity370 and @entity2 , the measurement of IgG against A60 and 38 kDa antigens in serum is more useful than that in BALF.

Serum and bronchoalveolar IgG against A60 and 38 kDa antigens in the diagnosis of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity370 :: ('MESH:D012507', 'Disease') :: ['sarcoidosis'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculous', 'tuberculosis'] @entity1907 :: ('MESH:D014397', 'Disease') :: ['pulmonary tuberculosis']
@entity378 :: (MESH:D014376,Disease) :: ['tuberculosis']
