PURPOSE: @entity11170 ( @entity11170 ) affect a large proportion of @entity0 ( @entity0 ) survivors and can negatively affect their quality of life. Treatments other than @entity172 replacement to alleviate @entity11170 are needed. Body weight is related to hot flashes, but little is known about the effect of weight change on @entity11170 . @entity1 AND METHODS: We used data from 3,088 @entity1 previously treated for early-stage @entity0 who were enrolled onto the @entity1 's Healthy Eating and Living study to examine the association between weight change after a @entity0 diagnosis and the odds of reporting @entity11170 . RESULTS: Overall, 36.1% of @entity1 reported moderate to severe @entity11170 at study entry. At 2 years postdiagnosis, 69.2% of @entity1 remained within 10%, 4.8% lost at least 10%, and 26.0% gained at least 10% of their prediagnosis weight. Those who gained at least 10% of their prediagnosis weight had a greater risk of reporting @entity11170 than @entity1 who remained weight stable in that same period (odds ratio [OR], 1.33; 95% CI, 1.11 to 1.60; P = .003). Weight loss of at least 10% of prediagnosis weight was associated with a nonsignificant reduced risk (OR, 0.72; 95% CI, 0.47 to 1.08; P = .118) of reporting @entity11170 . However, the trend of weight change ( @entity353 and @entity1017 ) on @entity11170 was significant both when examined categorically (P = .03) and continuously (P < .001). CONCLUSION: Prevention of @entity1017 after a @entity0 diagnosis-a modifiable behavior-may offer a viable intervention for relief of @entity11170 . Effects of intentional @entity353 in @entity0 survivors requires further study.

Effect of postdiagnosis weight change on hot flash status among XXXX survivors.

@entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Women', 'PATIENTS'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer', 'BC'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity1017 :: ('MESH:D015430', 'Disease') :: ['weight gain'] @entity11170 :: ('MESH:D019584', 'Disease') :: ['HF', 'Hot flashes']
@entity0 :: (MESH:D001943,Disease) :: ['early-stage breast cancer']
