UNASSIGNED: With the high prevalence of @entity4806 there is a need for structured physical activity during childhood. However, altered tibiofemoral loading during physical activity in @entity28 @entity1 likely contribute to their increased risk of @entity74 of the knee. The goal of this study was to determine the effects of @entity4806 and walking duration on medial and lateral tibiofemoral contact forces. We collected experimental biomechanics data during treadmill walking at 1 m   s(-1) for 20 minutes in 10 @entity28 and 10 healthy-weight 8-12 year-olds. We created subject-specific musculoskeletal models using radiographic measures of tibiofemoral alignment and centers-of-pressure, and predicted medial and lateral tibiofemoral contact forces at the beginning and end of each trial. @entity28 and walking duration affected tibiofemoral loading. At the beginning of the @entity2205 , the average percent of the total load passing through the medial compartment during stance was 85% in the @entity28 @entity1 and 63% in the healthy-weight @entity1 ; at the end of the trial, the medial distribution was 90% in the @entity28 @entity1 and 72% in the healthy-weight @entity1 . Medial compartment loading rates were 1.78 times greater in the @entity28 @entity1 . The medial compartment loading rate increased 17% in both groups at the end compared to the beginning of the trial (p=0.001). We found a strong linear relationship between body-fat percentage and the medial-lateral load distribution (r(2) =0.79). Altered tibiofemoral loading during walking in @entity28 @entity1 may contribute to their increased risk of knee @entity158 and pathology. This article is protected by copyright. All rights reserved.

XXXX and walking duration increase medial tibiofemoral compartment contact forces.

@entity1 :: ('9606', 'Species') :: ['participants', 'children'] @entity28 :: ('MESH:D009765', 'Disease') :: ['Obesity', 'obese'] @entity2205 :: ('8743', 'Gene') :: ['trail'] @entity4806 :: ('MESH:D063766', 'Disease') :: ['pediatric obesity'] @entity74 :: ('MESH:D030342', 'Disease') :: ['orthopedic disorders'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity4806 :: (MESH:D063766,Disease) :: ['Pediatric obesity']
