BACKGROUND: A cytogenetical study should be performed to every newborn with @entity600 . If a chromosomal aberration is found, parents must be studied to give an adequate genetic advise. AIM: To study the frequency of @entity2008 in newborns with @entity600 . @entity1 AND METHODS: In the Clinical Hospital of the University of Chile all @entity600 in newborns are registered, as part of the Collaborative Latin American Study of @entity600 (ECLAMC). The frequency of @entity2008 , determined by cytogenetical studies, was determined in newborns with @entity600 . RESULTS: In the study period, there were 32,214 births. Of these, 2,268 live newborns and 43 @entity2209 had @entity600 . Ninety nine @entity1 with @entity600 had @entity2008 (4.3%). Trisomy 21 was the most common aberration with a rate of 23/10,000 births, followed by @entity7440 with a rate of 4/10,000 and @entity7440 with a rate of 1.2/10,000. Ninety four percent of these @entity1 were born alive and 16.1% died before discharge from the hospital. The masculinity indexes for Down syndrome and for @entity7440 were 0.38 and 0.61 respectively. CONCLUSIONS: A higher frequency of female gender for trisomy 21 and male gender for @entity7440 has not been reported previously.

[Prevalence of XXXX at birth in the Clinical Hospital of Universidad de Chile, 1990-2001].

@entity1 :: ('9606', 'Species') :: ['children', 'PATIENTS'] @entity2209 :: ('MESH:D050497', 'Disease') :: ['stillbirths'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations', 'Congenital Malformations'] @entity2008 :: ('MESH:D002869', 'Disease') :: ['chromosomal aberrations'] @entity7440 :: ('MESH:C580500', 'Disease') :: ['trisomy 18']
@entity2008 :: (MESH:D002869,Disease) :: ['chromosomal aberrations']
