OBJECTIVE: The role of gender on long-term infrainguinal open surgery outcomes still remains uncertain in @entity63 @entity1 . The aim of this study is to evaluate the gender-specific differences in @entity1 characteristics and long-term clinical outcomes in terms of survival, primary patency and limb salvage among @entity1 undergoing infrainguinal open surgery for CLI. MATERIAL AND METHODS: All consecutive @entity1 undergoing infrainguinal open surgery for @entity63 between 2003 and 2012 were included. Survival, limb salvage and primary patency rates were assessed. Independent outcome determinants were identified by the Cox proportional hazard ratio using age and gender as adjustment factors. RESULTS: 584 @entity1 (269 @entity1 and 315 @entity1 , mean age 76 and 71 years respectively) underwent 658 infrainguinal open surgery (313 in @entity1 and 345 in @entity1 ). Survival rate at 6 years was lower among @entity1 compared to @entity1 with 53.5% vs 70.9% (p  <  0.001). The same applied to primary patency (35.9% vs 52.4%, p  <  0.001) and limb salvage (54.3% vs 81.1%, p  <  0.001) at 6 years. Female-gender was an independent factor predicting @entity204 (hazard ratio 1.50), @entity715 (hazard ratio 2.37) and limb loss (hazard ratio 7.05) in age and gender-adjusted analysis. CONCLUSION: Gender-related disparity in @entity63 open surgical revascularization outcomes still remains.

Gender related Long-term Differences after Open Infrainguinal Surgery for XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'men'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity63 :: ('MESH:D007511', 'Disease') :: ['critical limb ischemia']
@entity63 :: (MESH:D007511,Disease) :: ['Critical Limb Ischemia']
