OBJECTIVE: We recently showed that frozen section diagnosis has an almost perfect specificity for the diagnosis of @entity5 in an @entity4134 , whereas the sensitivity was, though good, not perfect. The aim of the present study was to examine whether the accuracy of frozen section diagnosis is affected by the size of the adnexal masses. METHODS: We included @entity1 that underwent frozen section diagnosis for @entity4134 surgery. For each @entity1 we recorded serum @entity10224 level, menopausal status, @entity5 size, and histologic classification both at frozen section diagnosis and at definite histological examination. We calculated sensitivity and specificity of frozen section diagnoses, both in @entity5 below and above 10 cm diameter. RESULTS: We included 257 @entity1 , of whom 142 had a @entity5 , 28 had a borderline @entity5 and 87 had a @entity5 at definitive histological assessment. In case frozen section diagnosis showed @entity5 , this was always confirmed at final histological assessment. In @entity1 with a @entity5 <10 cm, there was only 1 false negative diagnosis in 50 @entity1 with a benign frozen section diagnosis, whereas there were 11 false negative diagnoses in 97 @entity1 in @entity1 with a @entity5 > or = 10 cm. The corresponding likelihood ratios of a benign diagnosis for presence of @entity5 were .15 for @entity5 > or = 10 cm and 0.03 for @entity5 <10 cm, respectively. CONCLUSION: The accuracy of frozen section diagnosis is dependent on @entity5 size. In adnexal masses > or = 10 cm, a benign result of the frozen section diagnosis is less reliable than in @entity1 with a @entity5 <10 in cm.

The impact of size of the XXXX on the accuracy of frozen section diagnosis.

@entity5 :: ('MESH:D009369', 'Disease') :: ['benign tumour', 'tumours', 'malignant tumour', 'malignancy', 'tumour'] @entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient'] @entity10224 :: ('94025', 'Gene') :: ['CA125'] @entity4134 :: ('MESH:D000292', 'Disease') :: ['adnexal mass']
@entity4134 :: (MESH:D000292,Disease) :: ['adnexal mass']
