@entity150 is the 9th most common type of @entity5 and the 13th most common cause of @entity204 worldwide. C-erbB-4 is a class of oncogenes plays a role in @entity5 development. The present work was performed to assess C-erbB-4 oncogene amplification by PCR technology and its correlation with @entity876 and @entity588 . This study included 50 male @entity1 (10 controls and 40 @entity150 @entity1 ). The @entity150 @entity1 include 20 specimens diagnosed as @entity1606 ( @entity1606 ) and 20 specimens diagnosed as @entity957 ( @entity957 ). The results revealed that 7 (35%) of both @entity1606 and @entity957 showed @entity1722 gene amplification. 12 (60%) of @entity1606 and 6 (30%) of @entity957 showed positive expression of @entity876 . 11 (55%) of @entity1606 and 6 (30%) of @entity957 showed positive @entity588 expression. A direct statistically significant association was detected between @entity1722 expression and @entity588 and @entity876 expression in @entity1606 and @entity957 specimens. Seven (35%) of @entity1606 showed @entity1722 gene amplification and expression of both @entity876 and @entity588 . Five (25%) of the examined @entity957 specimens showed @entity1722 gene amplification and positive expression for both @entity876 and @entity588 . The results indicated that a direct statistically significant association was detected in @entity1606 group between amplification of @entity1722 gene by PCR and expressionof @entity876 and @entity588 by immunohistochemistry.

Expression of @entity1722 gene in XXXX of Egyptian @entity1 and its correlation with @entity876 and @entity588 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity588 :: ('596', 'Gene') :: ['Bcl-2', 'bcl-2'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma', 'SCC'] @entity876 :: ('7157', 'Gene') :: ['p53'] @entity150 :: ('MESH:D001749', 'Disease') :: ['Urinary bladder cancer', 'bladder cancer', 'urinary bladder cancer'] @entity1606 :: ('MESH:D002295', 'Disease') :: ['transitional cell carcinoma', 'TCC'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity1722 :: ('2064', 'Gene') :: ['c-erb-B2']
@entity150 :: (MESH:D001749,Disease) :: ['bladder cancer']
