PURPOSE: To investigate the effects of pre-block @entity1337 and sedation using @entity22730 on haemodynamic stability, endocrine stress response and @entity1 ' @entity158 perception. METHODS: In a randomized, single-blinded, placebo-controlled study, 60 @entity1 having @entity231 surgery with peribulbar block were randomly assigned into two groups: group A (n = 30) received 0.05 mg/kg @entity22730 (Dipidolor) intravenously; group B received normal saline intravenously prior to peribulbar block. Mean arterial pressure, heart rate, respiratory rate and pulse oximetry were recorded perioperatively. @entity158 from peribulbar block was assessed using a verbal analogue scale. Urinary excretion of @entity17081 was measured to assess the endocrine stress response. Using a questionnaire, @entity1 assessed their @entity148 and @entity615 before and during surgery. RESULTS: Mean arterial pressure remained near baseline in group A. In group B, a significant increase in mean arterial pressure after peribulbar block was found (p < 0.001). In addition, a significant increase in urinary excretion of @entity17081 was found in group B (p = 0.013). @entity158 scores (p < 0.001), @entity148 (p = 0.02) and during surgery (p < 0.001) and @entity615 (p = 0.003) were significantly lower in group A. CONCLUSION: The presented study suggests that using @entity22730 for @entity1337 and sedation prior to peribulbar block produces haemodynamic stability and reduces @entity158 perception and endocrine stress response.

Use of @entity22730 for XXXX and sedation during peribulbar nerve block for @entity231 surgery.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract'] @entity17081 :: ('MESH:D014642', 'Chemical') :: ['vanillylmandelic acid'] @entity1337 :: ('MESH:D000699', 'Disease') :: ['analgesia'] @entity22730 :: ('MESH:D010892', 'Chemical') :: ['piritramide'] @entity615 :: ('MESH:D001416', 'Disease') :: ['back pain'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety before nerve block', 'anxiety'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain', 'pain']
@entity1337 :: (MESH:D000699,Disease) :: ['analgesia']
