UNASSIGNED: OBJECT Case selection for the surgical treatment of @entity2758 ( @entity2758 ) of the eloquent motor area remains challenging. The aim of this study was to determine the risk factors for worsened @entity121 after surgery in @entity1 with this disorder. METHODS At their hospital the authors retrospectively studied 48 consecutive @entity1 with @entity2758 involving motor cortex and/or the descending pathway. All @entity1 had undergone preoperative functional MRI (fMRI) and diffusion tensor imaging (DTI), followed by resection. Both functional and angioarchitectural factors were analyzed with respect to the change in @entity121 . Functional factors included @entity75 ( @entity75 ) on DTI and lesion-to-activation area distance (LAD) and cortical reorganization on fMRI. Based on preoperative @entity121 , the changes in @entity121 at 1 week and 6 months after surgery were defined as short-term and long-term surgical outcomes, respectively. Statistical analysis was performed using the statistical package SPSS (version 20.0.0, IBM Corp.). RESULTS Twenty-one @entity1 (43.8%) had worsened @entity121 1 week after surgery. However, only 10 @entity1 (20.8%) suffered from @entity121 worsening 6 months after surgery. The @entity75 was significantly correlated with short-term (p < 0.001) and long-term (p < 0.001) surgical outcomes. For long-term outcomes, @entity1 in the 5 mm >=  @entity75 > 0 mm (p = 0.009) and @entity75 > 5 mm (p < 0.001) categories were significantly associated with a lower risk of permanent motor worsening in comparison with @entity1 in the @entity75 = 0 mm group. No significant difference was found between @entity1 in the 5 mm >=  @entity75 > 0 mm group and @entity75 > 5 mm group (p = 0.116). Nidus size was the other significant predictor of short-term (p = 0.021) and long-term (p = 0.016) outcomes. For long-term outcomes, the area under the ROC curve (AUC) was 0.728, and the cutoff point was 3.6 cm. Spetzler-Martin grade was not associated with short-term surgical outcomes (0.143), although it was correlated with long-term outcomes (0.038). CONCLUSIONS An @entity7026 with a nidus in contact with tracked eloquent fibers ( @entity75 = 0) and having a large size is more likely to be associated with worsened @entity121 after surgery in @entity1 with eloquent motor area @entity2758 . Surgical treatment in these @entity1 should be carefully considered. In @entity1 with an @entity75 > 5 mm, radical resection may be considered to eliminate the risk of @entity548 .

Risk factors for worsened @entity121 after the surgical treatment of XXXX of the eloquent motor area.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity7026 :: ('MESH:D002538', 'Disease') :: ['AVM'] @entity2758 :: ('MESH:D001165', 'Disease') :: ['arteriovenous malformations', 'AVMs'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity75 :: ('MESH:D001927', 'Disease') :: ['LCD', 'lesion-to-corticospinal tract distance'] @entity121 :: ('MESH:D009135', 'Disease') :: ['muscle strength']
@entity2758 :: (MESH:D001165,Disease) :: ['arteriovenous malformations']
