BACKGROUND: Internationally, hospital survival is lower for @entity1 admitted at weekends and at night. Data from the UK National @entity1167 Audit (NCAA) indicate that crude hospital survival was worse after in-hospital @entity1167 (IHCA) at night versus day, and at weekends versus weekdays, despite similar frequency of events. OBJECTIVE: To describe IHCA demographics during three day/time periods-weekday daytime (Monday to Friday, 08:00 to 19:59), weekend daytime (Saturday and Sunday, 08:00 to 19:59) and night-time (Monday to Sunday, 20:00 to 07:59)-and to compare the associated rates of return of spontaneous circulation (ROSC) for >20   min (ROSC>20   min) and survival to hospital discharge, adjusted for risk using previously developed NCAA risk models. To consider whether any observed difference could be attributed to differences in the case mix of @entity1 resident in hospital and/or the administered care. METHODS: We performed a prospectively defined analysis of NCAA data from 27   700 @entity1 aged >= 16   years receiving @entity2850 and attended by a hospital-based resuscitation team in response to a resuscitation (2222) call in 146 UK acute hospitals. RESULTS: Risk-adjusted outcomes (OR (95% CI)) were worse (p<0.001) for both weekend daytime (ROSC>20   min 0.88 (0.81 to 0.95); hospital survival 0.72 (0.64 to 0.80)), and night-time (ROSC>20   min 0.72 (0.68 to 0.76); hospital survival 0.58 (0.54 to 0.63)) compared with weekday daytime. The effects were stronger for non-shockable than shockable rhythms, but there was no significant interaction between day/time of arrest and age, or day/time of arrest and arrest location. While many daytime IHCAs involved procedures, restricting the analyses to IHCAs in medical admissions with an arrest location of ward produced results that are broadly in line with the primary analyses. CONCLUSIONS: IHCAs attended by the hospital-based resuscitation team during nights and weekends have substantially worse outcomes than during weekday daytimes. Organisational or care differences at night and weekends, rather than @entity1 case mix, appear to be responsible.

Risk-adjusted survival for adults following in-hospital XXXX by day of week and time of day: observational cohort study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2850 :: ('MESH:D009408', 'Disease') :: ['chest compressions and/or defibrillation'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['Cardiac Arrest', 'cardiac arrest']
@entity1167 :: (MESH:D006323,Disease) :: ['cardiac arrest']
