OBJECTIVE: To assess the level of serum lipoprotein(a) [ @entity3452 ] in nonobese and @entity28 @entity2175 subjects with android body distribution. RESEARCH DESIGN AND METHODS: Serum @entity3452 levels were measured in 30 long-standing @entity2175 @entity1 (duration of @entity6 12.5 +/- 3 years, mean +/- SD), with 15 of the @entity1 being @entity28 of android distribution (BMI > 30 kg/m2 and waist-to-hip ratio > 0.8). In addition, there were 15 android @entity28 nondiabetic subjects and 10 healthy subjects serving as the control group. RESULTS: All groups of @entity1 in this study ( @entity6 , and @entity28 @entity6 ) showed significantly higher levels of @entity3452 than the healthy control group. @entity3452 concentrations were significantly higher in @entity2175 @entity1 with android type of @entity28 than in nondiabetic androids (24.1 +/- 5.6 vs. 14.8 +/- 2.4 mg/dl, P < 0.001). Significantly greater levels of @entity3452 were found in nonobese subjects with @entity6 when compared with @entity28 subjects without @entity6 (22.3 +/- 4.1 vs. 14.8 +/- 2.4 mg/dl, P < 0.001). Furthermore, @entity3452 serum concentrations were not dependent on the degree of glycemic control (controlled @entity2175 23.6 +/- 5.0 vs. uncontrolled @entity2175 21.4 +/- 2.7 mg/dl, NS), but were much greater in subjects with @entity6 complicated by @entity455 (complicated 26.3 +/- 5.0 vs. uncomplicated 20.5 +/- 2.7 mg/dl, P < 0.001). No correlation was found between @entity3452 and other lipid parameters in this study. CONCLUSIONS: @entity3452 levels are significantly elevated in both @entity28 and nonobese @entity2175 @entity1 regardless of the degree of glycemic control. @entity3452 is an independent risk factor showing greater elevations in those subjects complicated with @entity532 .

Lipoprotein(a) in XXXX and @entity2175 .

@entity2175 :: ('MESH:D003924', 'Disease') :: ['NIDDM'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular disease'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic, obese', 'diabetic', 'diabetes'] @entity28 :: ('MESH:D009765', 'Disease') :: ['android-obese', 'obese', 'obesity'] @entity532 :: ('MESH:D003925', 'Disease') :: ['diabetic vascular diseases'] @entity3452 :: ('4018', 'Gene') :: ['Lp(a)']
@entity28 :: (MESH:D009765,Disease) :: ['android obesity']
