OBJECTIVES: Today a perforated peptic @entity1066 (PPU) is a rare condition. However, emergency surgery for perforated @entity1066 presently carries a mortality risk of up to 30%. The aim of this study is to analyze and define factors influencing surgical prognosis in @entity1 operated upon for PPU. METHODS: We performed a retrospective analysis of 62 @entity1 treated for PPU in Suleyman Demirel University, Surgical Department between January 1995 to January 2004. Univariate analysis was performed to determine risk factors for mortality in PPU by chi-square test, Pearson and Spearman correlation tests using SPSS for Windows statistical software. We accepted statistical significance for p values <0.05. RESULTS: The overall mortality rate was 17.7%. The present study confirms the age, sex, American Society of Anesthesiology (ASA) classification, coexisting medical disease, elapsed time from symptoms to operation, blood pressure, pulse, serum albumin and @entity1011 levels, hemoglobin level and diameter of perforation as valid prognostic factors in whole series, whereas a previous history of @entity10189 , chronic ingestion history of nonsteroidal anti-inflammatory drugs, @entity167 ingestion, smoking habits, site of perforation, type of surgical treatment (simple suture or resection), @entity260 did not appear to be related to prognosis. CONCLUSION: Age, gender, ASA classification, coexisting medical disease, elapsed time from symptoms to operation, blood pressure, pulse, serum albumin and @entity1011 levels, hemoglobin level and diameter of perforation are factors significantly associated with fatal outcomes in @entity1 undergoing emergency surgery for PPU. Thus, such factors need to be carefully taken into account during the general workup of @entity1 admitted for PPU.

Prognostic factors of peptic XXXX perforation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity10189 :: ('MESH:D010437', 'Disease') :: ['peptic ulcer disease'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative complications'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine']
@entity1066 :: (MESH:D014456,Disease) :: ['ulcer']
