OBJECTIVE: To explore the efficacy and safety of acupuncture for @entity64 ( @entity64 ). METHODS: The randomized, double-blind control study was designed. 43 post- @entity64 @entity1 with current @entity308 episode (DSM-IV) were randomly assigned to an observation group (23 cases) and a control group (20 cases). The conventional symptomatic, supportive and anti-infection treatment in neurological internal medicine was applied to all of the cases in two groups. In observation group, acupuncture was applied to Baihui (GV 20), Yintang (EX-HN 3), Sishencong (EX-HN 1), Taichong ( @entity8950 ), etc. Additionally, the placebo was taken orally. In control group, acupuncture was applied to non-acupoint spots (5 mm lateral to the acupoints selected in observation group) with shallow needling technique. Moreover, @entity905 was taken orally. The treatment lasted for 6 weeks. @entity308 ( @entity308 ), Asberg antidepressant side effect scale (ASES), adverse response of acupuncture and efficacy were compared between two groups. RESULTS: The total effective rate was 73.9% (17/23) in observation group and was 80.0% (16/20) in control group, indicating equivalent efficacy between two groups. After treatment, @entity308 score was reduced remarkably as compared with that before treatment in two groups (P < 0.05). ASES scores in 4 weeks of treatment and after treatment in observation group and ASES score after treatment in control group were reduced remarkably as compared with those before treatment (all P < 0.05). ASES scores in 4 weeks of treatment and after treatment in observation group were reduced much more remarkably as compared with those in control group (both P < 0.05). The incidences of adverse response of acupuncture were 13.0% (3/23) and 15.0% (3/20) respectively in observation group and control group, indicating that the adverse response was transient and had not recurred after symptomatic measures. CONCLUSION: Acupuncture for @entity64 is as effective as @entity905 , without obvious drug-induced adverse reaction involved.

[Acupuncture for XXXX : a randomized controlled trial].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['post-stroke depression', 'stroke', 'PSD'] @entity308 :: ('MESH:D003866', 'Disease') :: ['Hamilton Depression Scale', 'HAMD', 'major depression'] @entity905 :: ('MESH:D005473', 'Chemical') :: ['fluoxetine', 'Fluoxetine'] @entity8950 :: ('4041', 'Gene') :: ['LR 3']
@entity64 :: (MESH:D020521,Disease) :: ['post-stroke depression']
