BACKGROUND: @entity4854 in the neohepatic phase of liver transplantation (LT) tends to decrease toward completion of the surgical procedure. Refractory @entity4854 in the neohepatic phase (RH) is influenced by multiple perioperative factors and may be connected to posttransplant outcomes. We attempted to demonstrate the relationship of RH to posttransplant outcomes and to establish a predictive model for RH in living donor liver transplantation (LDLT). METHODS: Perioperative data of 211 @entity1 who underwent LDLT from 2009 and 2012 were reviewed, including declines in the @entity13897 levels during the neohepatic phase. Perioperative variables including the posttransplant @entity3851 ( @entity3851 ) score until day 30 were compared between @entity1 with normal declines in @entity13897 and @entity1 with RH. Selected variables after intergroup comparisons were examined by means of multivariate logistic regression to establish a predictive model for RH occurrence. RESULTS: The mean @entity13897 decline was 22.3    31.5  mg/dL during the neohepatic phase, and 84 of 203 @entity1 (41.4%) had no decline in @entity13897 . In intergroup comparisons, preoperative factors associated with RH included sex, @entity1 -Pugh-Turcotte class, @entity3851 score, emergency, liver enzymes, and graft-to-recipient weight ratio. During surgery, surgical time, serum lactate, and arterial pH were associated with RH. After surgery, the RH group showed slower recovery of the @entity3851 score (15.2 versus 11.9 days) and higher @entity3851 scores until day 10 (P  < .05). After the multivariate analysis, recipient sex, emergency, surgical time ( <=9  h), and the final intraoperative serum lactate level (>= 5.0  mmol/L) were included in the predictive model for RH. CONCLUSIONS: RH was associated with delayed functional recovery of the liver graft in LT. Recipient sex, emergency, surgical time, and the final intraoperative serum lactate level were identified as predictors of RH. Close monitoring of intraoperative @entity13897 in LDLT may be an early prognostic indicator.

Perioperative predictors for refractory XXXX during the neohepatic phase of liver transplantation.

@entity1 :: ('9606', 'Species') :: ['Child', 'patients'] @entity13897 :: ('MESH:D018149', 'Disease') :: ['blood glucose'] @entity4854 :: ('MESH:D006943', 'Disease') :: ['hyperglycemia', 'Hyperglycemia'] @entity3851 :: ('MESH:D058625', 'Disease') :: ['MELD', 'model for end-stage liver disease']
@entity4854 :: (MESH:D006943,Disease) :: ['hyperglycemia']
