Botulinum toxin type A (BoNT-A) has been reported to be an effective treatment for limb @entity508 after @entity64 . However, the reduction in the @entity508 after BoNT-A injection alone does not ensure an improvement in the active motor function of the affected limb. The aim of this study was to clarify the clinical effects of a BoNT-A injection, followed by home-based functional training on not only the passive but also the active motor function of the affected @entity508 upper limb in poststroke hemiparetic @entity1 . Eighty poststroke @entity1 with @entity508 upper @entity1269 were studied. The severity of @entity1269 was categorized as Brunnstrom stage of 3 for hand-fingers in all @entity1 . BoNT-A (maximum dose of 240 U) was injected into the target muscles of the affected upper limb after a clinical evaluation using the modified Ashworth scale, range of motion, Fugl-Meyer Assessment, and the Wolf Motor Function Test. Following the injection, occupational therapists provided home-based functional training for each @entity1 on a one-to-one basis. The follow-up evaluation was performed 4 weeks after the injection. A significant improvement was found in the modified Ashworth scale and range of motion. The changes in the Fugl-Meyer Assessment and the Wolf Motor Function Test indicated a significant improvement in the active motor function of the affected upper limb. In conclusions, our proposed protocol of a BoNT-A injection, followed by home-based functional training seems to have the potential to improve the active motor function of the affected upper limb after @entity64 , although the efficacy should be confirmed in a randomized-controlled trial.

Botulinum toxin type A injection, followed by home-based functional training for upper XXXX after @entity64 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity508 :: ('MESH:D009128', 'Disease') :: ['spasticity', 'spastic'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1269 :: ('MESH:D010291', 'Disease') :: ['hemiparesis', 'limb hemiparesis']
@entity1269 :: (MESH:D010291,Disease) :: ['limb hemiparesis']
