BACKGROUND: This study compared long-term survival in @entity788 treated with Whipple pancreatoduodenectomy (PD) and pylorus-preserving pancreatoduodenectomy (PPPD). METHODS: Two hundred twenty-one @entity1 with @entity788 were treated. Prognostic variables included age, gender, type and period of operation, and @entity5 stage. In the @entity420 variables also included @entity5 and node status, type of lymphadenectomy, pathologic grade, and presence of microscopic @entity41 . The end point was @entity204 as a result of neoplastic recurrence. Survival curves were estimated by using the Kaplan-Meier method, and multifactorial analysis was also performed on the data from the @entity420 group. RESULTS: The mortality rate was 8.2% in the PD group versus 7.0% in the PPPD group. Morbidity rates were 34.4% for PD and 45.8% for PPPD. Five-year survival was 9.6% in the @entity420 and 63.8% in the @entity189 groups. Univariate analysis failed to show statistically significant differences in survival curves between the two treatments in either @entity1 group. Correcting for multiple variables in the @entity420 group did not reveal any significant differences in survival rates between the two treatments. CONCLUSIONS: PPPD was as successful as classic PD in the treatment of @entity420 and @entity788 . Long-term survival was not influenced by the type of resection.

Long-term survival in XXXX : pylorus-preserving versus Whipple pancreatoduodenectomy.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic head or periampullary cancer', 'periampullary cancer of the pancreas', 'pancreatic or periampullary cancer'] @entity41 :: ('MESH:D018365', 'Disease') :: ['residual tumor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity189 :: ('MESH:D002277', 'Disease') :: ['periampullary carcinoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity420 :: ('MESH:D000230', 'Disease') :: ['ductal adenocarcinoma', 'ductal adenocarcinomas']
@entity788 :: (MESH:D010190,Disease) :: ['pancreatic cancer']
