OBJECTIVES: To investigate the feasibility and efficacy of salvage endoscopic extraperitoneal radical prostatectomy (EERPE) in cases of recurrent @entity263 after high-intensity focused ultrasound therapy (HIFU) or radiotherapy. METHODS: Nine @entity1 underwent salvage EERPE with curative intent for biopsy-proven, locally recurrent @entity263 . Of these 9 @entity1 , 3 had previously undergone HIFU and 6 radiotherapy. Perioperative parameters (operation time, estimated @entity190 , conversion to open surgery rate, transfusion rate, transurethral catheter time), functional outcome, and short-term oncologic outcome were reviewed. RESULTS: Mean @entity1 age was 63.3 years (range 48 to 74 years). Mean preoperative PSA value was 12.64 ng/mL and mean prostate weight was 49.2 g. Mean @entity190 was 238 mL. There was no need for conversion to open surgery or transfusion. Mean operation time was 148 minutes, and mean total transurethral catheter time was 6 days. No intraoperative complications were reported. There was no clear difference in operation difficulty between the post-HIFU and postradiotherapy EERPE. After a mean follow-up of 17 months, 7 @entity1 were completely continent, and 2 needed 1 to 2 pads per day. Three @entity1 were potent before the surgical treatment, but no @entity1 reported potency postoperatively. In 1 @entity1 a PSA relapse (1.20 ng/mL) was recognized 12 months postoperatively. CONCLUSIONS: Salvage EERPE after failed HIFU and radiation therapy is a safe and efficient method to treat locally recurrent @entity263 . Short-term oncologic and functional outcomes are promising, but further study should be made on the long-term oncologic outcomes of this technique.

Salvage laparoscopic extraperitoneal radical prostatectomy after failed high-intensity focused ultrasound and radiotherapy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss']
@entity263 :: (MESH:D011471,Disease) :: ['localized prostate cancer']
