OBJECTIVE: @entity1 presenting with poor-grade @entity510 ( @entity510 ) have commonly been reported to have a poor prognosis; however, several reports suggest a favorable outcome in a subgroup of @entity1 . We analyzed our database to identify factors determining functional outcome after poor-grade @entity510 . METHODS: During the period 2004-2014, 248 @entity1 with poor-grade @entity510 were treated in our institution. Poor-grade @entity510 was defined as World Federation of Neurological Surgeons grades IV-V on admission. Data including @entity1 characteristics, treatment modality, radiologic features, and functional neurologic outcome were assessed and further analyzed. Outcome was assessed according to the modified Rankin Scale after 6 months and stratified into favorable (modified Rankin Scale score 0-2) versus unfavorable (modified Rankin Scale score 3-6). A multivariate analysis was performed to identify predictors of functional outcome. RESULTS: A favorable outcome was achieved in 24% of @entity1 with poor-grade @entity510 . @entity1 with a favorable outcome were significantly younger (P  = 0.005), harbored significantly smaller @entity439 (P  = 0.004), and had a lower initial World Federation of Neurological Surgeons grade (P < 0.0001). An unfavorable outcome was significantly more frequent in @entity1 with additional space-occupying @entity1410 compared with @entity1 without additional space-occupying @entity1410 (P  = 0.0009). On multivariate analysis, @entity1 age, World Federation of Neurological Surgeons grade V, signs of @entity1779 , @entity439 size, and presence of space-occupying @entity1410 were identified as significant predictors of unfavorable outcome in @entity1 with poor-grade @entity510 . CONCLUSIONS: A favorable outcome was achieved in 24% of severely ill @entity1 with poor-grade @entity510 . Therefore, treatment of @entity1 with poor-grade @entity510 should not be omitted. Careful individualized decision making is necessary for each @entity1 .

Poor-Grade XXXX : Factors Influencing Functional Outcome-A Single-Center Series.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity510 :: ('MESH:D013345', 'Disease') :: ['aneurysmal subarachnoid hemorrhage', 'SAH'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms', 'aneurysm'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['cerebral herniation']
@entity510 :: (MESH:D013345,Disease) :: ['Aneurysmal Subarachnoid Hemorrhage']
