OBJECTIVES: To compare the characteristics of inter body fusion after using an established poly (D, L-lactic acid) (PDLLA) cage, a titanium cage or autologous tricortical iliac crest graft in a @entity1237 cervical spine model in vivo. METHODS: Twenty-four @entity1237 were assigned to three groups: PDLLA cage group (n = 8), titanium alloy cage group (n = 8) and autologous iliac bone group (n = 8), and underwent C3-4 discectomy and fusion with the allocated procedure. Radiography was performed pre- and post-operatively and after 1, 2, 4, 8 and 12 weeks and disc space height (DSH), @entity5513 ( @entity5513 ), and @entity1515 angle (LA) measured at these time points. After 12 weeks, the @entity1237 were killed and fusion sites removed. Biomechanical testing was performed in flexion, extension, @entity717 , and lateral bending to determine the stiffness and range of motion (ROM). All specimens were also assessed histomorphologically. RESULTS: The @entity5513 of PDLLA cage four weeks postoperatively and DSH eight and twelve weeks postoperatively were significantly greater than that of autologous iliac bone graft (P < 0.05). The LA values did not differ significantly between groups. The stiffness of both types of cages for @entity717 and lateral bending, and ROM for every movement, were significantly greater than that of the autologous iliac bone graft group (P < 0.05). PDLLA and titanium cages did not differ significantly (P > 0.05). Radiographic and histomorphological assessment showed better fusion in the cage than the autologous bone groups. CONCLUSION: The PDLLA cage can provide good intervertebral distract ability and enough biomechanical stability for cervical fusion.

Reconstruction of Segmental Stability of XXXX Cervical Spine with Poly (D, L-lactic acid) Cage.

@entity717 :: ('MESH:D009069', 'Disease') :: ['axial rotation'] @entity5513 :: ('MESH:D009464', 'Disease') :: ['intervertebral angle', 'IVA'] @entity1515 :: ('MESH:D008141', 'Disease') :: ['lordosis'] @entity1237 :: ('9925', 'Species') :: ['goats', 'goat']
@entity1237 :: (9925,Species) :: ['Goat']
