BACKGROUND: There is a renewed interest in pallidotomy as a treatment for complicated @entity191 ( @entity191 ). AIM: To present the clinical results as well as the analysis of prognostic factors obtained in 28 @entity1 with @entity191 submitted to pallidotomy and followed by one year (n = 28) and 2 years (n = 12). RESULTS: The total motor score (Unified @entity191 Rating Scale [UPDRS]) in the off state improved by 33 and 23% at one and two years, respectively (p < 0.01). All the cardinal signs of the disease were significantly improved (p < 0.01): @entity400 (92%), @entity2003 (67%), @entity2845 (46%) and axial symptoms (21%). A slight tendency to worsening in axial symptoms was observed. @entity910 disappeared in all but one @entity1 . The Schawb _ England Scale in off was improved by 21%. No improvement in the non-operated side was observed. The subgroup of @entity1 with an improvement of less than 30% in the UPDRS was older than the one with larger clinical benefit. The observed tendency to worsening in the total motor score was related mainly to the progression of the symptoms in the non-operated side. Complications were mild and transient. CONCLUSIONS: Pallidotomy is a relatively safe and effective therapeutic option for complicated @entity191 @entity1 . An adequate selection of @entity1 is necessary, since efficacy is partial and limited to one hemibody.

[Pallidotomy in the treatment of complicated XXXX : clinical results at two years and analysis of prognostic factors].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2003 :: ('MESH:D009127', 'Disease') :: ['rigidity'] @entity910 :: ('MESH:D004409', 'Disease') :: ['Dyskinesias'] @entity191 :: ('MESH:D010300', 'Disease') :: ['PD and motor complications', "Parkinson's Disease", "Parkinson's disease", 'PD'] @entity2845 :: ('MESH:D018476', 'Disease') :: ['bradykinesia'] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor']
@entity191 :: (MESH:D010300,Disease) :: ['Parkinson's disease']
