@entity3144 is defined by histologic features and can be observed in a wide range of entities. Independent of the causative disease, extracutaneous complications are frequent, mainly in the kidneys and gastrointestinal tract. It has been suggested that the severity of histological changes could correlate with the clinical course of the disease. We have therefore compared the severity of histological changes of @entity3144 to clinical and laboratory findings indicative of extracutaneous involvement in a large group of @entity1 . Among 289 @entity1 followed for @entity1333 , we included 184 @entity1 with purpuric papules and proven @entity3144 who all had standardized investigations. A cutaneous biopsy was performed early and standardized laboratory investigations were carried out. The slides were retrospectively randomized and the depth of @entity1333 and severity of @entity39 were determined according to a semiquantitative scale. These data were compared to the renal, gastrointestinal and articular symptoms using Fischer's exact test, Chi-square test and variance analysis. The intensity of @entity39 and the depth of @entity1333 were no more severe in @entity1 having renal changes, gastrointestinal involvement or articular symptoms. Both variance analysis and Chi-square tests failed to show a significant increase in the severity score in @entity1 having extracutaneous complications. In this study, the severity of histopathological changes was not predictive of extracutaneous involvement. Thus it appears that the degree of involvement of the cutaneous vessels probably does not correlate with that of vessels in visceral organs.

The severity of histopathological changes of XXXX is not predictive of extracutaneous involvement.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3144 :: ('MESH:C535509', 'Disease') :: ['Leukocytoclastic vasculitis', 'leukocytoclastic vasculitis'] @entity39 :: ('MESH:D009336', 'Disease') :: ['vascular necrosis'] @entity1333 :: ('MESH:D014657', 'Disease') :: ['cutaneous vasculitis', 'vasculitis']
@entity3144 :: (MESH:C535509,Disease) :: ['leukocytoclastic vasculitis']
