We have examined 26 retrieved, failed @entity702 -alloy femoral stems. The clinical details, radiological appearances and the histology of the surrounding soft tissues in each @entity1 were also investigated. The stems were predominantly of the flanged design and had a characteristic pattern of wear. A review of the radiographs showed a series of changes, progressive with time. The first was lateral debonding with subsidence of the stem. This was followed by calcar resorption and fragmentation or @entity174 of the cement. Finally, @entity3061 was seen, starting with a radiolucency at the cement-bone interface and progressing to endosteal cavitation. Three histological appearances were noted: granulomatous, @entity16925 and @entity39 . We suggest that an unknown factor, possibly related to the design of the stem, caused it to move early. After this, micromovement at the cement-stem interface led to the generation of particulate debris and @entity174 of the cement. A soft-tissue reaction to the debris resulted in @entity3061 and failure of fixation of the prostheses.

A retrieval study of capital hip prostheses with XXXX alloy femoral stems.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrotic'] @entity3061 :: ('MESH:D010014', 'Disease') :: ['osteolysis'] @entity16925 :: ('MESH:D017441', 'Disease') :: ['necrobiotic'] @entity702 :: ('MESH:D014025', 'Chemical') :: ['titanium']
@entity702 :: (MESH:D014025,Chemical) :: ['titanium']
