BACKGROUND: The aim of the present study was to evaluate the efficacy and safety of intraperitoneal microdialysis in early detection of @entity834 after low anterior resection for @entity5 . METHODS: In a series of 116 consecutive @entity1 scheduled for low anterior resection for @entity5 , a total of 50 @entity1 consented to participate. Peritoneal microdialysis was performed by a 1 mm thin catheter anchored in close proximity to the @entity254 . Five @entity1 were excluded due to catheter malfunction. Average microdialysis time in the remaining 45 @entity1 was 177.6 (80-252) hours. Samples were collected every 4-hours, and the concentration of @entity413 , @entity880 , @entity2388 and @entity653 was measured. RESULTS: Four @entity1 developed symptomatic @entity834 . Two @entity1 developed @entity1661 . In 38 @entity1 the postoperative course was uncomplicated, considering major complications, and they served as controls. In three @entity1 with late (>or=10 days) @entity834 a significant increase in concentration of @entity880 and @entity880 / @entity2388 ratio (L/P-ratio) was seen several days prior to development of clinical symptoms. In one @entity1 with early @entity834 it coincided with the development of clinical symptoms. In the two @entity1 with @entity1661 the values were within normal range. CONCLUSION: Peritoneal microdialysis is a safe and promising tool in early diagnosis of @entity834 after low anterior resection for @entity5 .

Peritoneal microdialysis. Early diagnosis of @entity834 after low anterior resection for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity834 :: ('MESH:D057868', 'Disease') :: ['anastomotic leakage'] @entity5 :: ('MESH:D009369', 'Disease') :: ['rectosigmoid cancer'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity1661 :: ('MESH:D000008', 'Disease') :: ['non-abdominal sepsis'] @entity653 :: ('MESH:D005990', 'Chemical') :: ['glycerol'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity2388 :: ('MESH:D019289', 'Chemical') :: ['pyruvate']
@entity5 :: (MESH:D009369,Disease) :: ['rectosigmoid cancer']
