BACKGROUND: Magnetic resonance imaging (MRI) patterns of @entity235 cervical hydrated nucleus pulposus extrusion (HNPE) have been described by a few reports, but the correlation between microsurgical and MRI features has never been investigated. The aim of this study was to compare the MRI features of HNPE with microsurgical findings and cytological outcomes and also to investigate the anatomical and pathophysiological aspects of the disease. METHODS: A prospective clinical study was conducted in 36 @entity235 suffering from HNPE. The diagnosis was based on high-field MRI findings of ventral extradural lesions, adjacent to the dorsal aspect of intervertebral discs, characterised by high signal intensity in T2-weighted sequences and hypointensity in T1-weighted sequences. MRI images were analysed with regard to the intervertebral space involved, the grading of @entity1745 , the signal intensity and distribution of the material, and the thickness and signal intensity of the involved discs. All @entity1 underwent microsurgical decompression and direct observations were recorded and films of the surgical procedure analysed. RESULTS: The majority of @entity1 had acute onset of clinical signs (78  %), the @entity1 did not exhibit signs of @entity158 in 75  % of @entity235 and @entity51 varied from slight tetraparesis (33  %) to @entity1688 (28  %). The localization of the extruded disc material was ventral relative to the dorsal longitudinal ligament that was lifted dorsally and appeared intact at the site of compression. Direct microsurgical observations of the HNPE sites showed that extruded disc material was collected within the fibres of the dorsal longitudinal ligament. The consistency was gelatinous in 42  %, water-like in 33  %, and lumpy liquid in 25  % of cases. Cytological samples did not detect the presence of @entity32 , bacteria, fungi, neoplastic cells or foreign material. CONCLUSIONS: Microsurgical features of HNPE suggest that the extruded disc is collected within the fibres of the dorsal longitudinal ligament and this may explain the typical MRI appearance of this disease. Further pathophysiological studies are needed to investigate why the cervical nucleus pulposus extrusion appears to occur without obvious @entity130 .

Hydrated nucleus pulposus extrusion in XXXX : correlation of magnetic resonance imaging and microsurgical findings.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1688 :: ('MESH:D011782', 'Disease') :: ['tetraplegia'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity235 :: ('9615', 'Species') :: ['canine', 'dogs'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficits'] @entity1745 :: ('MESH:D013117', 'Disease') :: ['spinal cord compression'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity235 :: (9615,Species) :: ['dogs']
