OBJECTIVE: To study the incidence of biopsy-proven @entity226 ( @entity226 ) in a Hispanic population with clinical features suggestive of @entity226 . DESIGN: Retrospective review. @entity1 : Records of 121 consecutive @entity1 who underwent temporal artery biopsy at the Doheny Eye Institute and the Los Angeles County/University of Southern California Hospital from January 1986 through April 1998 were reviewed. MAIN OUTCOME MEASURES: The incidence of biopsy-proven @entity226 was determined, and the biopsy-positive group was compared with the biopsy-negative group. Study variables included age at diagnosis, gender, erythrocyte sedimentation rate (ESR), and ethnic background. RESULTS: Among these 121 @entity1 who underwent temporal artery biopsy, the mean age of those in the biopsy-positive group (75.2 +/- 5.0 years) was higher than that of those in the biopsy-negative group (69.1 +/- 9.2 years; P < 0.0001). There was no statistical correlation between biopsy-positive and biopsy-negative groups for gender or ESR level, but ESR was statistically significant for whites when we controlled for race. Nineteen of 66 white @entity1 (29%) had positive biopsy results, whereas only 1 of the 9 Asian @entity1 (11%) none of the 40 Hispanic @entity1 (0%; P < 0.0001) and none of the 6 African American @entity1 (0%) had positive biopsy results. CONCLUSIONS: @entity226 occurs primarily in the white population. None of the Hispanic @entity1 in our study was found to have positive biopsy results. Hispanic @entity1 may have unknown factors that protect them from this disease. Further study is necessary to examine the genetic predisposition.

The epidemiology of XXXX : a 12-year retrospective study.

@entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS', 'persons'] @entity226 :: ('MESH:D013700', 'Disease') :: ['giant cell arteritis', 'GCA', 'Giant cell arteritis']
@entity226 :: (MESH:D013700,Disease) :: ['giant cell arteritis']
