This study tested the hypothesis that @entity717 would result in improved @entity174 healing compared to interfragmentary @entity717 . Ten skeletally mature merino @entity742 underwent a middiaphyseal osteotomy of the right tibia, stabilized by external fixation with an interfragmentary gap of 3 mm. A custom made external fixator allowed either pure axial (n=5) or pure @entity717 (n=5) of 1.5 mm amplitude during locomotion by the animals. The movement of the osteotomy gap was monitored weekly in two @entity742 by an extensometer temporarily attached to the fixator. After 8 weeks the @entity742 were killed, and @entity446 was evaluated by radiography, biomechanical testing, and undecalcified histology. Shear movement considerably delayed the @entity3602 . Bridging of the @entity1949 occurred in all osteotomies in the axial group (100%), while in the shear group only three osteotomies (60%) were partially bridged. @entity1897 formation in the shear group was reduced by 36% compared to the axial group (p<0.05). In the axial group bone formation was considerably larger at the peripheral callus and in between the osteotomy gaps but not in the intramedullary area. The larger peripheral callus and excess in bone tissue at the level of the gap resulted in a more than three times larger mechanical @entity2003 for the axial than for the shear group (p<0.05). In summary, fixation that allows excessive @entity717 significantly delayed the @entity3602 compared to healing under axial movement of the same magnitude.

Shear movement at the @entity174 site delays healing in a diaphyseal XXXX model.

@entity3602 :: ('MESH:D003966', 'Disease') :: ['healing of diaphyseal osteotomies'] @entity1949 :: ('MESH:D012892', 'Disease') :: ['osteotomy fragments'] @entity2003 :: ('MESH:D009127', 'Disease') :: ['rigidity'] @entity742 :: ('9940', 'Species') :: ['sheep'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity1897 :: ('MESH:D010523', 'Disease') :: ['Peripheral callus'] @entity717 :: ('MESH:D009069', 'Disease') :: ['interfragmentary axial movement of transverse diaphyseal osteotomies', 'shear movement'] @entity446 :: ('MESH:C563468', 'Disease') :: ['healing of the osteotomies']
@entity174 :: (MESH:D050723,Disease) :: ['fracture']
