BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to be inversely related to @entity191 and @entity195 , both of which may share common mechanisms with essential @entity400 (ET). Use of these medications has not been studied in ET cases vs. controls. OBJECTIVE: To investigate the relationships between NSAID (esp. @entity5018 ) and @entity117 use and ET. METHODS: Subjects were enrolled in a case-control study of the environmental epidemiology of ET at the Columbia University Medical Center (CUMC; 2009-2014). We compared 92 ET cases to 107 controls (   1:1 matching) in terms of self-reported NSAID (esp. @entity5018 ) and @entity117 use. RESULTS: The proportion of NSAID or @entity117 users (current or past) was similar in ET cases and controls (for current user, p = 0.66; for past user, p = 0.90). Among users, however, the total dosage of @entity5018 (frequency in past year * number of tablets taken at a time * typical average strength of tablets) was higher in controls than ET cases (p = 0.04). ET cases and controls did not differ with respect to @entity117 use in the past year. CONCLUSION: The proportion of NSAID or @entity117 users did not differ in ET cases or controls; yet interestingly, @entity5018 use was less in ET cases than in controls. The latter raises the possibility that @entity5018 use could have a potential protective role in ET.    2014 S. Karger AG, Basel.

Non-steroidal anti-inflammatory drug use and essential XXXX .

@entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity5018 :: ('MESH:D007052', 'Chemical') :: ['ibuprofen'] @entity191 :: ('MESH:D010300', 'Disease') :: ["Parkinson's disease"] @entity400 :: ('MESH:D014202', 'Disease') :: ['tremor'] @entity195 :: ('MESH:D000544', 'Disease') :: ["Alzheimer's disease"]
@entity400 :: (MESH:D014202,Disease) :: ['tremor']
