BACKGROUND AND AIMS: Perforation during colonoscopy remains the most worrisome adverse event and usually requires urgent surgical rescue. The aim of this study was to evaluate the feasibility and effectiveness of endoscopic closure of full-thickness @entity694 . METHODS: We performed a retrospective analysis of all consecutive @entity1 with endoscopically closed @entity694 over the past 6 years (2009-2014). @entity694 were closed by using endoscopic clips or an endoscopic suturing device. Most @entity1 were admitted for treatment with intravenous antibiotics and kept on bowel rest. If their clinical condition deteriorated, urgent surgery was performed. If @entity1 remained stable, oral feeding was resumed, and @entity1 were discharged with subsequent clinical and endoscopic follow-up. RESULTS: Twenty-one @entity1 had iatrogenic @entity694 closed with an endoscopic suturing device or endoscopic clips during the study period. Primary closure of a colonic perforation was performed with endoscopic clips in 5 @entity1 and sutured with an endoscopic suturing device in 16 @entity1 . All 5 @entity1 after clip closure had worsening of @entity490 and required laparoscopy (4 @entity1 ) or rescue colonoscopy with endoscopic suturing closure (1 @entity1 ). Two @entity1 had @entity490 after endoscopic suturing closure, but diagnostic laparoscopy confirmed complete and adequate endoscopic closure of the perforations. The other 15 @entity1 did not require any rescue surgery or laparoscopy after endoscopic suturing. The main limitation of our study is its retrospective, single-center design and relatively small number of @entity1 . CONCLUSION: Endoscopic suturing closure of @entity694 is technically feasible, eliminates the need for rescue surgery, and appears more effective than closure with hemostatic endoscopic clips.

Endoscopic management of XXXX : clips versus suturing closure (with videos).

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity694 :: ('MESH:D003110', 'Disease') :: ['Colonic perforations', 'colonic perforations'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain']
@entity694 :: (MESH:D003110,Disease) :: ['colonic perforations']
