PURPOSE: To describe ophthalmic findings with emphasis on exophthalmometry and ultrasonic assessment of extraocular eye muscle diameter in a consecutive group of females with @entity2743 ( @entity2743 ), compared with healthy controls and @entity1 with other @entity1374 . We also investigated the relationship with biochemical markers of thyroid autoimmunity such as TSH receptor antibodies (TRAb) and anti-thyroid peroxidase antibodies (anti-TPO). METHODS: Seventy adult @entity1 (age 26-74 years) with various types of @entity1374 consecutively entered the study at a tertiary referral center for @entity6875 ( @entity6875 ). Twenty-three had long-standing @entity2743 with @entity6875 . Clinically, @entity6875 was mainly absent in 22 with newly diagnosed @entity2743 and in seven with relapse of @entity2743 . Nine with @entity2621 and nine with @entity1376 were included for comparison and 18 healthy females served as controls. A full ophthalmic status included B-scan ultrasonic assessment of the four horizontal rectus muscle thicknesses, and a clinical NOSPECS score was attempted for each. RESULTS AND CONCLUSIONS: Besides higher NOSPECS scores, the @entity6875 subgroup had higher exophthalmometry and muscle thickness. The @entity2743 groups without significant @entity6875 also scored higher in these ratings compared to controls. Hertel recordings, NOSPECS and muscle thicknesses were all correlated in @entity2743 but showed no correlation to thyroid antibodies (TRAb and anti-TPO). Thus, the muscle thickness did not correlate with thyroid autoimmune activity. Nevertheless, we found extraocular muscle assessment useful since a) thicker muscles were usually found in @entity1 with @entity2743 , with or without evidence of @entity6875 , and b) other space-occupying orbital lesions could be excluded, thereby reducing the need for the more elaborate imaging techniques (CT, MRI, etc.). (Eur J Ophthalmol 2002; 12: 351-8).

Ultrasound measurement of the horizontal external eye muscles in @entity1 with XXXX . Is orbital involvement associated with thyroid autoantibodies?

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity2743 :: ('MESH:D006111', 'Disease') :: ['GD', 'Graves disease'] @entity2621 :: ('MESH:D050031', 'Disease') :: ['Hashimotos thyroiditis'] @entity1376 :: ('MESH:C564546', 'Disease') :: ['multinodular goiter'] @entity6875 :: ('MESH:D049970', 'Disease') :: ['TAO', 'thyroid-associated ophthalmopathy'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroid disease', 'thyroid diseases']
@entity1374 :: (MESH:D013959,Disease) :: ['thyroid disease']
