BACKGROUND: Primary treatment of @entity1162 ( @entity1162 ) currently consists of beta-blocker therapy, although an @entity737 ( @entity737 ) is considered for high-risk @entity1 . However, both overdiagnosis and overtreatment must be avoided because their sequelae can be significant. OBJECTIVE: The purpose of this study was to evaluate the prevalence and details of @entity737 explants in a cohort of @entity1 from a tertiary genetic heart rhythm clinic for a previously rendered diagnosis of @entity1162 . METHODS: Overall, 1227 consecutive @entity1 were included in the study. All @entity1 had been referred to the Mayo Clinic for evaluation of possible @entity1162 and subsequently were either diagnosed with @entity1162 or dismissed as normal. Further stratification of @entity1 was conducted to assess how many @entity1 had an @entity737 and how many had a subsequent @entity737 explant. RESULTS: In total, 170 @entity1 (14%) had an @entity737 , including 157 of 670 @entity1 (23%) with confirmed @entity1162 and 13 of 557 @entity1 (2%) who did not have @entity1162 . Among these, 12 of 1227 (1%) had the @entity737 removed: 7 of 157 @entity1162 @entity1 (4.5%) compared to 5 of 14 non- @entity1162 @entity1 (36%). Before explant, 5 of 12 @entity1 (42%) experienced inappropriate shocks, ranging from 2 to as many as 54 shocks. In addition, 4 had a @entity281 , and 9 had @entity1652 (including lead dysfunction or @entity174 ). None of these @entity1 had a breakthrough cardiac event since removal of their @entity737 during 5.5    3.5 years of follow-up. CONCLUSION: Implications of overdiagnosis and overtreatment are profound because unnecessary @entity737 placement can be associated with @entity281 , malfunction, inappropriate shocks, and subsequent @entity148 .

Implantable cardioverter-defibrillator explantation for overdiagnosed or overtreated XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity174 :: ('MESH:D050723', 'Disease') :: ['fracture'] @entity1652 :: ('MESH:D009471', 'Disease') :: ['device malfunction'] @entity737 :: ('MESH:D057873', 'Disease') :: ['ICD', 'implantable cardioverter-defibrillator'] @entity281 :: ('MESH:D007239', 'Disease') :: ['device-related infection', 'infection'] @entity148 :: ('MESH:D001008', 'Disease') :: ['anxiety'] @entity1162 :: ('MESH:D008133', 'Disease') :: ['LQTS', 'long QT syndrome']
@entity1162 :: (MESH:D008133,Disease) :: ['congenital long QT syndrome']
