OBJECTIVES: To assess the efficacy of early invasive strategy for the treatment of Braunwald III-B type unstable @entity951 . METHODS: This study included 573 consecutive @entity1 of whom 267 underwent percutaneous coronary intervention (PCI) (312 lesions). The @entity1 were divided into two groups, 95 treated with the early invasive strategy of coronary angiography within 24 hr of admission (Group PCI-I) and the remaining 172 treated with the early conservative strategy of coronary angiography 24 hr after admission (Group PCI-C). RESULTS: No significant differences were noted in the baseline characteristics of the two groups except for ST segment elevation on electrocardiography at presentation, which occurred significantly less frequently in Group PCI-C (36.8% vs 8.1%, p < 0.0001). The initial success rate of percutaneous coronary intervention was sufficiently high in both groups (Group PCI-I: 96.9% vs Group PCI-C: 97.7%, NS). Acute @entity583 occurred in six @entity1 of Group PCI-C (3.5%) because of the side branch occlusion. There was no in-hospital @entity204 or emergent coronary artery bypass grafting. During the 6-month follow-up, there were no significant differences in the @entity204 rates (2.1% vs 1.7%), the @entity204 or @entity583 rates (5.3% vs 5.8%) and the @entity75 revascularization ratio (26.0% vs 25.7%) between Group PCI-I and Group PCI-C. CONCLUSIONS: The clinical outcomes of the early invasive strategy for unstable @entity951 were almost equivalent to those of the early conservative strategy, despite more frequent ST segmental elevation at admission in Group PCI-I. These findings suggest that the early invasive strategy for unstable @entity951 may be acceptable even in the current Japanese clinical setting without the use of GP IIb/IIIa receptor antagonist, low molecular weight heparin or @entity1397 .

[Clinical significance of early percutaneous coronary intervention in XXXX with Braunwald III-B type unstable @entity951 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity75 :: ('MESH:D001927', 'Disease') :: ['target lesion'] @entity1397 :: ('MESH:C055162', 'Chemical') :: ['clopidogrel'] @entity951 :: ('MESH:D000787', 'Disease') :: ['angina pectoris'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1 :: (9606,Species) :: ['patients']
