PURPOSE: The purpose of this study was to assess left ventricular (LV) function by gated SPECT in @entity1375 . METHODS: Thirty-eight acute @entity1375 @entity1 without any @entity299 and 40 healthy controls underwent gated SPECT at rest. Fourteen @entity1 had a second examination during @entity1955 replacement therapy. Gated SPECT was performed using Tc-99m sestamibi with 16 frames per cardiac cycle. The LV end-diastolic volume (EDV), end-systolic volume ( @entity5778 ), ejection fraction (EF), peak ejection rate (PER), peak filling rate (PFR), and time to peak filling (TTPF) were measured by quantitative gated SPECT (QGS). Systolic wall thickening/motion was determined in 5 myocardial segments. RESULTS: @entity1375 @entity1 exhibited a decrease in PFR (222 +/- 52 EDV/s) and prolongation of TTPF (194 +/- 32 msec) as compared with controls (247 +/- 41 EDV/s and 179 +/- 17 msec, respectively; P < 0.05). During @entity1955 therapy, the mean values for EDV (74 +/- 21 mL) and PFR (265 +/- 64 EDV/s) increased significantly in 14 follow-up @entity1 (pretreatment values 67 +/- 18 mL and 219 +/- 50 EDV/s, respectively; P < 0.05). A significant difference was detected in the mean TTPF between the @entity1955 group and the controls (195 +/- 35 msec vs 179 +/- 17 msec; P < 0.05). No significant differences were found in wall thickening and motion values (P > 0.05). CONCLUSION: Gated SPECT findings revealed @entity67 as indicated by a decrease in PFR and a prolongation in TTPF in @entity1 with @entity1375 .

Gated SPECT findings revealing XXXX in @entity1375 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1375 :: ('MESH:D007037', 'Disease') :: ['Hypothyroid', 'acute hypothyroidism', 'hypothyroid'] @entity1955 :: ('MESH:D013974', 'Chemical') :: ['thyroxine'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac disease'] @entity67 :: ('MESH:D018754', 'Disease') :: ['diastolic dysfunction'] @entity5778 :: ('1127767', 'Species') :: ['ESV']
@entity67 :: (MESH:D018754,Disease) :: ['diastolic dysfunction']
