The relation between myocardial functional changes and the apoptosis-related proteins in @entity1 with @entity384 ( @entity384 ) has not yet been reported. The purpose of this study was to assess this issue through the use of @entity452 stress echocardiography. A total of 81 segments of left ventricles (from 6 @entity1 with @entity384 ) were collected in this study. Segments from another 5 @entity1 who had died of noncardiac causes were used as the control. Apoptosis-related proteins ( @entity589 , @entity588 , and @entity876 ) and apoptosis were evaluated in these segments by immunocytochemical stain and terminal deoxynucleotidyl transferase-mediated DNA nick end-labeling assay. There were 26 segments with @entity452 -induced contractile reserve. There were significant differences in numbers of segments with overexpression of @entity588 and @entity589 in the study and control groups. However, @entity876 was not found in either group. The total terminal deoxynucleotidyl transferase-mediated DNA nick end-labeling-positive nuclei in explanted hearts of @entity384 was 0.73%. The myocardial contractile reserve was inversely associated with an overexpression of @entity588 (P <.01) rather than @entity589 . In conclusion, the expression of @entity589 and @entity588 proteins in @entity1 with @entity384 is enhanced and independent of @entity876 . Loss of contractile reserve is associated with overexpression of @entity588 protein in failing myocardium.

The correlation between expression of apoptosis-related proteins and myocardial functional reserve evaluated by @entity452 stress echocardiography in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity589 :: ('581', 'Gene') :: ['bax'] @entity452 :: ('MESH:D004280', 'Chemical') :: ['dobutamine'] @entity588 :: ('596', 'Gene') :: ['bcl-2'] @entity384 :: ('MESH:D002311', 'Disease') :: ['DCM', 'dilated cardiomyopathy'] @entity876 :: ('7157', 'Gene') :: ['p53']
@entity384 :: (MESH:D002311,Disease) :: ['dilated cardiomyopathy']
