Postnatal @entity2295 has been previously considered synonymous with angiogenesis but it was found that circulating endothelial progenitor cells may home into sites of @entity2295 and their differentiation into endothelial cells is consistent with vasculogenesis. In this study, we investigated @entity2295 of the adult @entity35 's cerebral cortex after surgical @entity1545 by electron microscopic ultrastructural and immunocytochemical studies. We found places with disrupted @entity75 . The blood vessels showed an incomplete endothelial lining. In the @entity75 we observed fibrin, likely derived from disrupted blood vessels. In the plasma there were cell aggregates characterized by endothelial-like features with fibrils in the cytoplasm, untypical for endothelial cells. These endothelial-like cells participated in the process of new vessel formation. We used the anti-alpha(v) beta3 integrin antibody to visualize the different morphogenic stages of newly formed blood vessels. We demonstrated the relationship between alpha(v) beta3 integrin localization and different stages of new vessel formation. Our data suggest that growth and development of new blood vessels due to @entity2295 following trauma of the adult @entity35 brain are not restricted to angiogenesis but encompass vasculogenesis as well.

New vessel formation after surgical XXXX in the @entity35 's cerebral cortex I. Formation of the blood vessels proximally to the surgical injury.

@entity35 :: ('10116', 'Species') :: ['rat'] @entity2295 :: ('MESH:D015861', 'Disease') :: ['neovascularization'] @entity75 :: ('MESH:D001927', 'Disease') :: ['brain parenchyma'] @entity1545 :: ('MESH:D020214', 'Disease') :: ['brain injury']
@entity1545 :: (MESH:D020214,Disease) :: ['brain injury']
