UNASSIGNED: Nanosponges (NSs) are a new age branched @entity70117 (CD) polymeric systems exhibiting tremendous potential in pharmaceutical, agro science, and biomedical applications. Over the past decade, different varieties of @entity7031 based on the type of CD and the crosslinker have been developed tailored for specific applications. @entity7031 technology has been instrumental in achieving solubilization, stabilization, sustained release, enhancement of activity, permeability enhancement, protein delivery, ocular delivery, stimuli sensitive drug release, enhancement of bioavailability, etc. There is a major explosion of research in the area of @entity7031 -aided @entity5 therapeutics. A wide of anticancer molecules both from a pharmacological and physicochemical perspective have been developed as @entity7031 formulations by several groups including ours. Our objective in this review is to capture a systematic and comprehensive snapshot of the state-of-the-art of @entity7031 -aided @entity5 therapeutics reported so far. This review will provide an ideal platform for both the formulation scientists working on new polymeric/drug development and @entity5 biologists/scientists to understand the current nanotechnologies in CD-based @entity7031 -aided @entity5 therapeutics. The scope of the review is limited to small molecules and CD-based @entity7031 . The review covers in detail the problems associated with anticancer small molecules, and the solution provided by CD-based @entity7031 specifically for @entity9800 , @entity6108 , @entity1311 , @entity440 , @entity4025 , @entity3092 , @entity26 - @entity7031 , @entity2903 , @entity632 , and @entity1487 . For further resources related to this article, please visit the WIREs website.

Cyclodextrin-based nanosponges: a versatile platform for XXXX nanotherapeutics development.

@entity632 :: ('MESH:D004317', 'Chemical') :: ['doxorubicin'] @entity440 :: ('MESH:D013629', 'Chemical') :: ['tamoxifen'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1311 :: ('MESH:D017239', 'Chemical') :: ['paclitaxel'] @entity6108 :: ('MESH:D003474', 'Chemical') :: ['curcumin'] @entity70117 :: ('CHEBI:23456', 'Chemical') :: ['cyclodextrin'] @entity7031 :: ('MESH:D056770', 'Disease') :: ['NS'] @entity9800 :: ('MESH:D002166', 'Chemical') :: ['camptothecin'] @entity2903 :: ('MESH:C047246', 'Chemical') :: ['temozolomide'] @entity4025 :: ('MESH:C059514', 'Chemical') :: ['resveratrol'] @entity3092 :: ('MESH:D011794', 'Chemical') :: ['quercetin'] @entity1487 :: ('MESH:D005472', 'Chemical') :: ['5-Fluorouracil']
@entity5 :: (MESH:D009369,Disease) :: ['cancer']
