UNASSIGNED: Shivering associated with spinal anesthesia during Cesarean delivery is an uncomfortable experience for the parturient, which may also cause adverse effects. In this prospective, randomized, double-blind, placebo-controlled study, we sought to evaluate the effect of intrathecal @entity6948 , administered as an adjunct to hyperbaric @entity1341 for Cesarean delivery, on the incidence and severity of shivering associated with spinal anesthesia. @entity1 undergoing Cesarean delivery were randomly allocated to three groups of 30 @entity1 each. Experimental treatments were added to hyperbaric @entity1341 as follows: @entity1 in group I (control) were administered isotonic saline. @entity1 in groups II and III received @entity6948 (2.5, 5     g, respectively), mixed with isotonic saline. Shivering was observed in 11, 10 and 2 @entity1 in groups I, II and III, respectively. The incidence of shivering in group III was significantly lower than that in groups I (p=0.005) and II (p=0.01). The severity of shivering was significantly different between the three groups (p=0.01). There were no significant inter-group differences with respect to mean arterial pressure and heart rate at any time point after administration of intrathecal local anesthesia (p>0.05). Intrathecal @entity6948 (5     g) administered as an adjunct to hyperbaric @entity1341 during Cesarean delivery significantly reduced the incidence and intensity of shivering associated with spinal anesthesia.

Intrathecal XXXX Alleviates Shivering during Cesarean Delivery under Spinal Anesthesia.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity1341 :: ('MESH:D002045', 'Chemical') :: ['bupivacaine'] @entity6948 :: ('MESH:D020927', 'Chemical') :: ['dexmedetomidine']
@entity6948 :: (MESH:D020927,Chemical) :: ['Dexmedetomidine']
