UNASSIGNED: @entity63 ( @entity63 ) is a powerful innate response to transient subcritical @entity63 that protects against severe @entity63 insults at distant sites. We have previously shown the safety and feasibility of limb @entity63 in @entity510 ( @entity510 ) @entity1 , along with changes in neurovascular and cerebral metabolism. In this study, we aim to detect the potential effect of an established lower-limb conditioning protocol on clinical outcomes of @entity510 @entity1 . Neurologic outcome (modified Rankin Scale (mRS)) of @entity1 enrolled in a prospective trial (RIPC-SAH) was measured. A matching algorithm was applied to identify control @entity1 with @entity510 from an institutional departmental database. @entity63 @entity1 underwent four lower-limb conditioning sessions, consisting of four 5-min cycles per session over nonconsecutive days. Good functional outcome was defined as mRS of 0 to 2. The study population consisted of 21 @entity63 @entity1 and 61 matched controls. There was no significant intergroup difference in age, gender, @entity439 location, clipping vs coiling, Fisher grades, Hunt and Hess grades, or @entity2553 . @entity63 was independently associated with good outcome (OR 5.17; 95  % confidence interval (CI) 1.21-25.02). @entity63 also showed a trend toward lower incidence of @entity64 (28.6 vs. 47.5  %) and @entity204 (4.8 vs. 19.7  %). @entity63 following @entity510 appears to have a positive effect in the functional outcomes of @entity1 with @entity510 . While this effect is consistent with prior preclinical studies, future trials are necessary to conclusively evaluate the effects of @entity63 for @entity510 .

Matched Cohort Analysis of the Effects of Limb Remote Ischemic Conditioning in XXXX with @entity510 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity510 :: ('MESH:D013345', 'Disease') :: ['aneurysmal subarachnoid hemorrhage', 'aSAH'] @entity63 :: ('MESH:D007511', 'Disease') :: ['Lower-limb RIC', 'Remote ischemic conditioning', 'RIC', 'ischemia', 'ischemic'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysm'] @entity2553 :: ('MESH:D020301', 'Disease') :: ['vasospasm'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1 :: (9606,Species) :: ['Patients']
