BACKGROUND: Current methods to establish the diagnosis of @entity378 are inadequate. OBJECTIVES: We aimed to determine the clinical features of @entity378 and evaluate inflammatory biomarkers in intestinal as well as @entity1907 . METHODS: We recruited 38 @entity378 @entity1 , 119 @entity1907 @entity1 and 91 controls with functional @entity344 between October 2009 and July 2012 for the investigation of clinical features, @entity1851 ( @entity1851 ), faecal and serum calprotectin. Faecal calprotectin >= 200     g/g was used as a cut-off to determine intestinal inflammation of clinical significance. Three @entity1 categories were established: (a) @entity1907 and faecal calprotectin <200     g/g (isolated @entity1907 ); (b) @entity1907 and faecal calprotectin >= 200     g/g (combined pulmonary and @entity378 ); (c) isolated @entity378 . RESULTS: Common clinical features of @entity378 were @entity490 , @entity1295 , @entity353 and watery @entity294 . Intestinal @entity378 @entity1 had elevated median @entity1851 (10.7   mg/l), faecal calprotectin (320     g/g) and serum @entity1190 (5.7     g/ml). Complete normalisation of @entity1851 (1.0   mg/L), faecal calprotectin (16     g/g) and serum calprotectin (1.4     g/ml)) was seen upon clinical remission. @entity1 with combined pulmonary and @entity378 had the highest levels of @entity1851 (53.8   mg/l) and serum calprotectin (6.5     g/ml) and presented with signs of more severe disease. CONCLUSION: Calprotectin analysis reveals @entity378 in @entity1 with @entity1907 and pinpoints those in need of rigorous follow-up.

Faecal calprotectin levels differentiate intestinal from XXXX : An observational study from Southern India.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity1190 :: ('MESH:D039841', 'Chemical') :: ['calprotectin'] @entity1907 :: ('MESH:D014397', 'Disease') :: ['pulmonary tuberculosis'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhoea'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal disorders'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity378 :: ('MESH:D014376', 'Disease') :: ['intestinal tuberculosis', 'tuberculosis'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein', 'CRP']
@entity1907 :: (MESH:D014397,Disease) :: ['pulmonary tuberculosis']
