BACKGROUND: @entity136 is a key drug for the treatment of @entity788 . @entity1 equilibrative @entity8742 transporter 1 ( @entity11573 ) is a major transporter responsible for @entity136 uptake into cells. This study was conducted to elucidate the association between expression level of @entity11573 and outcome for @entity788 @entity1 treated with neoadjuvant therapy including @entity136 . METHODS: Sixty-three @entity1 who underwent neoadjuvant chemoradiation followed by curative surgery for @entity1124 were included. Immunohistochemistry was performed using resected specimens and the staining intensity of @entity11573 was scored as having no staining, low staining, or high staining; the former two were defined as negative expression of @entity11573 . The association between expression level of @entity11573 and overall survival was evaluated by Cox proportional regression model. RESULTS: Expression level of @entity11573 was evaluated as positive in 22 (35%) @entity1 , and as negative in 41 (65%) @entity1 . Univariate analysis showed that regional lymph node @entity3 , vascular permeation, and perineural invasion are prognostic factors; however, expression level of @entity11573 did not reach statistical significance. Multivariate analysis showed only vascular permeation as a prognostic factor. CONCLUSIONS: Expression level of @entity11573 was not associated with prognosis for @entity788 @entity1 who were treated with neoadjuvant chemoradiation including @entity136 .

@entity1 equilibrative XXXX transporter 1 level does not predict prognosis in @entity788 @entity1 treated with neoadjuvant chemoradiation including @entity136 .

@entity1 :: ('9606', 'Species') :: ['patients', 'Human'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic cancer'] @entity1124 :: ('MESH:D021441', 'Disease') :: ['pancreatic ductal adenocarcinomas'] @entity8742 :: ('D009705', 'Chemical') :: ['nucleoside'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity11573 :: ('2030', 'Gene') :: ['hENT1'] @entity136 :: ('MESH:C056507', 'Chemical') :: ['Gemcitabine', 'gemcitabine']
@entity8742 :: (D009705,Chemical) :: ['nucleoside']
