INTRODUCTION: The main objective of the study was to determine the frequency of @entity1 receiving inappropriate empiric antibiotic therapy and to assess the impact in terms of increase length of hospital stay, 30-day re-admissions, and 30-day mortality. METHODS: An observational retrospective cohort study was conducted over a one-month period that included all @entity1 hospitalised from an @entity341 ( @entity341 ) due to @entity281 . Demographic variables, comorbidity, multi-resistance risk factors, site of @entity281 , microbiological findings, and antibiotic prescribed in @entity341 were collected. Outcomes were length of hospital stay, 30-day re-admissions, and 30-day mortality. RESULTS: A total of 376 @entity1 were included, with a mean age of 71.1 (SD 21) years. The most frequent causes were respiratory (45.7%) and urine (23.9%) infections. The number of @entity1 with length of stay over the median (>= 9 days) was 165 (46.1%), with re-admissions 74 (19.7%), and mortality at 30 days 44 (11.7%). There was inappropriate antibiotic treatment in 42 (11.2%) cases. After adjusting for demographic data, comorbidity, risk factors for multidrug resistant organism, presence of @entity295 criteria in @entity341 , and site of @entity281 , inappropriate treatment was associated with an extended length of hospital stay (OR 2.22; 95% CI; 1.07-4.60; P=.032), but did not to an increase in mortality (P=.271) or re-admission (P=.784) at 30 days. CONCLUSION: The inappropriate empirical antibiotic therapy in @entity1 admitted from the @entity341 leads to an extended hospital stay, but did not increase mortality or readmission.

[Effect of the inadequacy of antibiotic therapy in the XXXX on hospital stays].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity341 :: ('MESH:D004630', 'Disease') :: ['ED', 'Emergency Department'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis']
@entity341 :: (MESH:D004630,Disease) :: ['Emergency Department']
