BACKGROUND: Several observational studies have suggested a superior survival after mitral valve repair compared with replacement in @entity1 undergoing surgery for @entity884 . The objective of this study was to systematically review the rate of morbidity and mortality associated with mitral valve repair or replacement in @entity884 . METHODS: A Medline search was conducted for literature and a systematic review of 24 studies, reporting prognosis of @entity1 who underwent surgery for mitral @entity340 , was performed. Information on the @entity1 , type of surgery, and follow-up was abstracted using standardized protocols. RESULTS: A total of 470 @entity1 (39%) underwent mitral valve repair and 724 @entity1 (61%) underwent valve replacement. Lower in-hospital mortality (2.3% versus 14.4%, relative risk: 0.16, 95% confidence interval: 0.09 to 0.30, p < 0.0001) and long-term mortality (7.8% versus 40.5%, relative risk: 0.19, 95% confidence interval: 0.13 to 0.29, p < 0.0001) were observed among @entity1 undergoing mitral valve repair compared with replacement. In addition, the rates of early reoperation (2.2% versus 12.7%, p < 0.0001), early cerebrovascular events (4.7% versus 11.5%, p = 0.045), late reoperation (4.7% versus 8.7%, p = 0.039), late recurrent @entity884 (1.8% versus 7.3%, p = 0.0013), and late cerebrovascular events (1.6% versus 24.4%, p < 0.0001) were significantly lower after mitral valve repair. Meta-regression analysis demonstrated that mitral valve repair over replacement was associated with a better early and late prognosis after surgery. Male sex and acute surgery were (nonsignificantly) predictive of worse early outcome. CONCLUSIONS: A systematic review of literature showed that mitral valve repair is associated with good clinical in-hospital and long-term results among @entity1 undergoing surgery for @entity884 .

Mitral valve repair and replacement in XXXX : a systematic review of literature.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity340 :: ('MESH:D006349', 'Disease') :: ['valve endocarditis'] @entity884 :: ('MESH:D004696', 'Disease') :: ['infective endocarditis', 'endocarditis']
@entity884 :: (MESH:D004696,Disease) :: ['endocarditis']
