AIM: To investigate whether 7-d triple therapies are still valid in populations with low levels of resistance. METHODS: A total of 1106 @entity1534 ( @entity1534 )-positive @entity1 were divided into three groups, each of which received one type of 7-d triple therapy. Therapeutic outcomes of the @entity1 were assessed by the @entity7352 - @entity1133 breath test at 8 wk after treatment. The susceptibility of H. @entity1534 to antibiotics was determined by an agar-dilution method. Data analysis was performed by   (2) tests. RESULTS: The eradication rates in groups A, B and C were 90.71% (332/366), 90.46% (313/346) and 90.87% (189/208), respectively (P = 0.986). The resistance rates were 8.91% for @entity4581 , 14.78% for @entity5553 and 0% for @entity115 . The eradication rate was significantly different between @entity4581 - and @entity5553 -resistant @entity1 (P < 0.05) in group A. @entity1 whose treatment failed in group A also had a higher @entity4581 resistance rate than did successive @entity1 (P = 0.034). However, @entity5553 resistance had no obvious influence on the eradication rate. Furthermore, three main antibiotics ( @entity4581 , @entity5553 and @entity115 ) had lower DID (defined daily dose per 1000 inhabitants per day) in this city. CONCLUSION: @entity4581 resistance is the main reason for the failure of 7-d triple therapy. In populations with low levels of resistance, a 7-d triple therapy is a viable choice. The choice of therapy should not be influenced by conditions in high antibiotic resistance regions.

Seven-day triple therapy is a better choice for XXXX eradication in regions with low antibiotic resistance.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity115 :: ('MESH:D000658', 'Chemical') :: ['amoxicillin'] @entity1133 :: ('MESH:D014508', 'Chemical') :: ['urea'] @entity4581 :: ('MESH:D017291', 'Chemical') :: ['Clarithromycin', 'clarithromycin'] @entity7352 :: ('CHEBI:36928', 'Chemical') :: ['(13)C'] @entity5553 :: ('D064704', 'Chemical') :: ['levofloxacin'] @entity1534 :: ('210', 'Species') :: ['H. pylori', 'pylori', 'Helicobacter pylori']
@entity1534 :: (210,Species) :: ['Helicobacter pylori']
