BACKGROUND: Factors determining predictability of response to thymectomy for @entity1737 ( @entity1737 ) vary in the literature. METHODS: A 25-year retrospective review (1974 to 1999) of all thymectomies performed at a single institution was undertaken. RESULTS: In 113 consecutive thymectomies for @entity1737 , @entity1 comprised 79% (89 of 113 @entity1 ), and mean age was 40+/-15 years. Complications occurred in 14% of @entity1 (16 of 113). In-hospital mortality was 0, but 90-day hospital mortality was 0.88% (1 of 113 @entity1 ). Follow-up was obtained in 81% (92 of 113 @entity1 ) at a mean of 51+/-59 months postoperatively. Complete remission was achieved in 21% of @entity1 (19 of 92), and marked improvement of @entity1737 in 54% (50 of 92), for a total benefit rate of 75%. Fourteen percent (13 of 92) were unchanged, and 11% (10 of 92) were worse. Using univariate analysis, sex, age, and pathology correlated significantly with outcome (p < 0.05): 80% of @entity1 (57 of 70) benefited from the procedure, versus 57% of @entity1 (12 of 21). Eighty percent (57 of 70) of @entity1 less than 51 years of age were improved or in remission, versus 57% (12 of 22) older than 50. Twenty-three percent (5 of 22) of @entity1 with @entity704 deteriorated, versus 7.1% (5 of 70) without @entity704 . Sex did not significantly correlate in the multivariate model. CONCLUSIONS: Sex, age, and thymic pathology are potential predictors of outcome in thymectomy for @entity1737 , and may shape treatment decisions and target higher-risk @entity1 .

Predictors of outcome in thymectomy for XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity1737 :: ('MESH:D009157', 'Disease') :: ['MG', 'myasthenia gravis'] @entity704 :: ('MESH:D013945', 'Disease') :: ['thymoma']
@entity1737 :: (MESH:D009157,Disease) :: ['myasthenia gravis']
