BACKGROUND: A subset of @entity1 with severe @entity472 ( @entity472 ) have lower @entity64 volumes and valve gradients despite a normal left ventricular ejection fraction (LVEF), referred to as paradoxical low-flow @entity472 (PLF @entity472 ). However, the role of right ventricular (RV) function in @entity1 with severe @entity472 and preserved LVEF is not known. We hypothesized that right ventricular function is associated with left @entity64 in @entity1 with severe @entity472 and preserved LVEF. METHODS: From an echocardiographic database, we retrospectively identified 102 @entity1 with an indexed aortic valve area  <=0.6  cm(2) /m(2) and LVEF  >=   50%. We used univariate and multivariate linear regression analysis to assess the association between aortic valve @entity64 volume index (SVi) and right ventricular systolic function as measured by tricuspid annular plane systolic excursion (TAPSE) and by right ventricular fractional area change (FAC). RESULTS: Our population was 98% male with mean age 77.4      9.3  years and mean SVi of 36.1      7.9 mL/m(2) . Forty-four @entity1 (43%) met criteria for PLF @entity472 . TAPSE and FAC were positively associated with SVi in both univariate and multivariate regression analysis after correcting for left ventricular variables (b coefficient - TAPSE (cm): 4.59      1.3, P  =  0.001; FAC (%): 0.19      0.08, P  =  0.014). Additionally, PLF @entity472 @entity1 had significantly lower mean TAPSE and lower mean FAC when compared dichotomously to normal flow @entity472 @entity1 (P  <  0.05). CONCLUSIONS: Right ventricular systolic function assessed by TAPSE and FAC is significantly related to aortic valve flow in @entity1 with severe @entity472 and preserved LVEF.

Right Ventricular Function Is Associated with Left XXXX Volume in @entity1 with Severe Aortic Stenosis and Preserved Ejection Fraction.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity472 :: ('MESH:D001024', 'Disease') :: ['AS', 'aortic stenosis'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'ventricular stroke volume']
@entity64 :: (MESH:D020521,Disease) :: ['Ventricular Stroke']
