BACKGROUND: Endovascular stenting is a recognised treatment strategy for @entity1498 (CoA) in adults. We assessed systemic @entity101 control and the need for antihypertensive therapy after CoA stenting in adults. METHODS: Data were collected prospectively on 54 @entity1 (36 @entity1 ; mean age: 34  16 years) who underwent endovascular stenting for CoA over a 7-year period. Five @entity1 were excluded as they did not attend follow-up appointments. @entity1 underwent clinical examination, including right arm systolic blood pressure (SBP) and 24-hour ambulatory blood pressure monitoring at baseline, 6-12 weeks and 9-12 months. RESULTS: There was a significant fall in mean peak-to-peak systolic gradient (PG) across the CoA after stenting (26  11mmHg vs. 5  4mmHg; P<0.01). There were successive reductions in right arm SBP and ambulatory SBP at baseline, 6-12 weeks and 9-12 months post-procedure (right arm: 155  18mmHg vs. 137  17mmHg vs. 142  16mmHg, respectively; all P-values <0.01; ambulatory: 142  14mmHg vs. 132  16mmHg vs. 131  15mmHg, respectively; all P-values <0.01). Twenty-four @entity1 had severe CoA (PG >25mmHg before stenting); baseline SBP was significantly higher in severe versus non-severe @entity1 (160mmHg vs. 148mmHg; P=0.02). The absolute reduction in PG after stenting was significantly higher in the severe group (31  7mmHg vs. 14  5mmHg; P<0.0001), but there was no significant difference in SBP between groups at 6-12 weeks (141mmHg vs. 135mmHg; P=0.21) or 9-12 months (139mmHg vs. 139mmHg; P=0.96). CONCLUSION: Endovascular stenting of CoA results in a significant reduction in SBP at 6-12 weeks, which is sustained at 9-12 months, with similar outcomes in severe and non-severe CoA groups.

Benefit of endovascular stenting for XXXX on systemic @entity101 in adults.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity1498 :: ('MESH:D001017', 'Disease') :: ['aortic coarctation'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension']
@entity1498 :: (MESH:D001017,Disease) :: ['aortic coarctation']
