STUDY DESIGN: Retrospective cohort analysis. OBJECTIVE: To compare clinical outcomes after spine instrumentation and fusion using 3 different bone grafts in @entity1 with @entity1615 ( @entity1615 ). SUMMARY OF BACKGROUND DATA: @entity79 ( @entity16282 ) is the "gold standard" to promote fusion in posterior @entity1615 operations, although the morbidity of harvest is a concern. There is limited data comparing outcomes after @entity1615 surgery based on types of bone grafts. METHODS: @entity1 (10-18 yr) with @entity1615 who underwent deformity correction via a posterior approach were identified in the @entity85 Study Group database. All had a minimum of 2-year follow-up. @entity1 were subdivided into 3 groups based on bone graft used: @entity16282 , allograft, and @entity79 ( @entity79 ). Clinical data included @entity1 demographics, operative details, postoperative analgesic use, and perioperative complications. Lenke curve type and curve magnitude changes were radiographically analyzed. The Scoliosis Research Society-30 questionnaire was used to assess clinical outcomes. RESULTS: 461 @entity1 met inclusion criteria ( @entity1 : 381, @entity1 : 80; average age 14.7    1.7) and consisted of 152 @entity16282 @entity1 (124 @entity1 , 28 @entity1 ), 199 allograft @entity1 (167 @entity1 , 32 @entity1 ), and 110 @entity79 @entity1 (90 @entity1 , 20 @entity1 ). There was no difference in age (P = 0.41) or gender (P = 0.82). The @entity79 group had significantly smaller preoperative curves and shorter operative times. Postoperatively, @entity1 who received @entity79 had significantly longer hospital stays, used higher quantities of @entity1 -controlled intravenous analgesia and used epidurals longer. The @entity16282 group used @entity1 -controlled intravenous analgesia significantly longer. There were no differences between the groups in regards to curve type, number of levels fused, @entity86 , @entity1516 , reoperations for any indication, and Scoliosis Research Society-30 scores at the latest follow-up. CONCLUSION: Outcomes after primary posterior spinal fusion with instrumentation are not influenced by type of bone graft or substitute. LEVEL OF EVIDENCE: 3.

Type of bone graft or substitute does not affect outcome of spine fusion with instrumentation for XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'Children', 'patient', 'girls', 'boys'] @entity1615 :: ('OMIM:181800', 'Disease') :: ['AIS', 'adolescent idiopathic scoliosis'] @entity16282 :: ('MESH:D058540', 'Disease') :: ['AIC'] @entity79 :: ('MESH:D001847', 'Disease') :: ['Autogenous iliac crest bone graft', 'BS', 'bone substitute'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative infections'] @entity85 :: ('MESH:D009140', 'Disease') :: ['Spinal Deformity'] @entity1516 :: ('MESH:D011542', 'Disease') :: ['pseudarthrosis']
@entity1615 :: (OMIM:181800,Disease) :: ['adolescent idiopathic scoliosis']
