BACKGROUND: @entity1 treated with radical prostatectomy (RP) or @entity1161 ( @entity1161 ) for @entity263 can experience stress and symptoms that impact quality of life. OBJECTIVE: The objectives of this study were to describe @entity701 levels, perceived stress, symptoms, and symptom distress; compare differences in variables measured between RP and @entity1161 ; and identify associations among @entity701 levels, perceived stress, symptoms, and symptom distress in @entity1 treated for @entity263 . METHODS: A descriptive, cross-sectional study was conducted with 53 @entity1 (RP n = 24, @entity1161 n = 29). Data from saliva, questionnaires, and interviews were collected within 3 months of treatment. Saliva samples were collected at 4 times over 2 consecutive days. Data were analyzed using descriptive statistics, correlations, and regressions. RESULTS: A robust diurnal rhythm of @entity701 secretion with heightened levels in the early morning and lowered levels late in the day was found. On average, the entire sample had moderate symptoms and symptom distress for urinary, bowel, and @entity250 . The RP group reported significantly more urinary and @entity250 and fewer bowel symptoms than did the @entity1161 group. Perceived stress was positively correlated with higher afternoon @entity701 levels and greater symptom distress. CONCLUSION: Moderate symptoms and symptom distress found in our sample indicate the need for interventions to address these outcomes in @entity1 treated for @entity263 . Self-reported perceived stress can be used to assess the stress level and symptom distress in clinic setting. IMPLICATIONS FOR PRACTICE: @entity1 treated for @entity263 with RP or @entity1161 should be assessed for symptoms and symptom distress and targeted for early symptom management interventions.

High perceived stress is linked to afternoon @entity701 levels and greater symptom distress in XXXX with @entity263 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity263 :: ('MESH:D011471', 'Disease') :: ['localized prostate cancer', 'prostate cancer'] @entity1161 :: ('MESH:D011832', 'Disease') :: ['radiation therapy', 'RT'] @entity701 :: ('MESH:D006854', 'Chemical') :: ['cortisol'] @entity250 :: ('MESH:D012735', 'Disease') :: ['sexual dysfunction', 'sexual dysfunction symptoms']
@entity1 :: (9606,Species) :: ['patients']
