The purposes of this study were: to describe chest CT findings in normal non-smoking controls and cigarette smokers with and without @entity1030 ; to compare the prevalence of @entity854 with severity of @entity1030 ; and to evaluate concordance between visual and quantitative chest CT (QCT) scoring. METHODS: Volumetric inspiratory and expiratory CT scans of 294 subjects, including normal non-smokers, smokers without @entity1030 , and smokers with GOLD Stage I-IV @entity1030 , were scored at a multi-reader workshop using a standardized worksheet. There were 58 observers (33 pulmonologists, 25 radiologists); each scan was scored by 9-11 observers. Interobserver agreement was calculated using kappa statistic. Median score of visual observations was compared with QCT measurements. RESULTS: Interobserver agreement was moderate for the presence or absence of @entity2415 and for the presence of panlobular @entity2415 ; fair for the presence of centrilobular, paraseptal, and @entity2415 subtypes and for the presence of @entity2488 ; and poor for gas trapping, centrilobular nodularity, mosaic attenuation, and @entity384 . Agreement was similar for radiologists and pulmonologists. The prevalence on CT readings of most abnormalities (e.g. @entity2415 , @entity2488 , mosaic attenuation, expiratory gas trapping) increased significantly with greater @entity1030 severity, while the prevalence of centrilobular nodularity decreased. Concordances between visual scoring and quantitative scoring of @entity2415 , gas trapping and airway wall thickening were 75%, 87% and 65%, respectively. CONCLUSIONS: Despite substantial inter-observer variation, visual assessment of chest CT scans in cigarette smokers provides information regarding lung disease severity; visual scoring may be complementary to quantitative evaluation.

A combined pulmonary-radiology workshop for visual evaluation of XXXX : study design, chest CT findings and concordance with quantitative evaluation.

@entity2488 :: ('MESH:D001982', 'Disease') :: ['bronchial wall thickening'] @entity384 :: ('MESH:D002311', 'Disease') :: ['bronchial dilation'] @entity2415 :: ('MESH:D004646', 'Disease') :: ['bullous emphysema', 'emphysema'] @entity854 :: ('MESH:D018376', 'Disease') :: ['CT abnormalities'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['COPD']
@entity1030 :: (MESH:D029424,Disease) :: ['COPD']
