OBJECTIVE: To explore the physiological factors affecting exercise-induced changes in peak @entity26 consumption and function poststroke. DESIGN: Single-center, single-blind, randomized controlled pilot trial. SETTING: Community @entity64 services. @entity1 : Adults (N=40; age>50y; independent with/without stick) with @entity64 (diagnosed >6mo previously) were recruited from 117 eligible @entity1 . Twenty @entity1 were randomized to the intervention group and 20 to the control group. No dropouts or adverse events were reported. INTERVENTIONS: Intervention group: 19-week (3times/wk) progressive mixed (aerobic/strength/balance/flexibility) community group exercise program. CONTROL GROUP: Matched duration home stretching program. MAIN OUTCOME MEASURES: (1) Pre- and postintervention: maximal cardiopulmonary exercise testing with noninvasive (bioreactance) cardiac output measurements; and (2) functional outcome measures: 6-minute walk test; timed Up and Go test, and Berg Balance Scale. RESULTS: Exercise improved peak @entity26 consumption (18  5 to 21  5mL/(kg   min); P<.01) and peak arterial-venous @entity26 difference (9.2  2.7 to 11.4  2.9mL of @entity3612 /100mL of blood; P<.01), but did not alter cardiac output (17.2  4 to 17.7  4.2L/min; P=.44) or cardiac power output (4.8  1.3 to 5.0  1.35W; P=.45). A significant relation existed between change in peak @entity26 consumption and change in peak arterial-venous @entity26 difference (r=.507; P<.05), but not with cardiac output. Change in peak @entity26 consumption did not strongly correlate with change in function. CONCLUSIONS: Exercise induced peripheral muscle, but not cardiac output, adaptations after @entity64 . Implications for @entity64 clinical care should be explored further in a broader cohort.

Exercise Induces Peripheral Muscle But Not Cardiac Adaptations After XXXX : A Randomized Controlled Pilot Trial.

@entity1 :: ('9606', 'Species') :: ['participants', 'PARTICIPANTS'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity3612 :: ('D013481', 'Chemical') :: ['O2']
@entity64 :: (MESH:D020521,Disease) :: ['Stroke']
