PURPOSE: @entity5 ( @entity5 ) is a very rare odontogenic lesion, with most  knowledge based on single case reports. Therefore, a comprehensive analysis was performed of  the clinical and radiologic features of reported cases of @entity5 with an emphasis on treatment modalities. MATERIAL AND METHODS: This is a case series of DGCTs collected from the literature after a systematic search of Medline's PubMed and Google Scholar. Three additional cases were included from the authors' files. Demographic data of the @entity1 , lesion site and size, and radiologic features were analyzed. Treatment approach and events of recurrence were recorded. RESULTS: Forty-five cases (42 from the literature) were included. The mean age of @entity1 was 39.7    19.3  years (range, 12 to 79  yr) and the male-to-female ratio was 1.8:1. The mandible-to-maxilla ratio was 1.14:1, with the posterior region of the jaws being the most commonly involved site. Radiographically, 78% lesions were unilocular, 67% were mixed radiolucent and radiopaque, and 68% had well-defined borders. The mean lesion size was 4.0  cm (range, 1.8 to 13.0  cm). The primary treatment for 21 @entity1 was conservative surgery consisting of enucleation or curettage. Follow-up information for longer than 1  year (mean, 6.2    8.3  yr; range, 1 to 31  yr) was known for 15 @entity1 , of whom 11 (73%) had recurrences. The primary treatment in 19 @entity1 was radical surgery consisting of marginal or segmental resection. Follow-up information for longer than 1  year (mean, 3.3    2.6  yr; range, 1 to 10  yr) was known for 12  @entity1 , of whom 4 (33%) had recurrences. CONCLUSIONS: This study highlighted the potentially aggressive biological behavior of DGCTs that demands extensive surgery and long follow-up. However, owing to the rarity of @entity5 , more well-documented cases with long follow-up periods are needed to further define the optimal treatment modalities and prognosis.

Central XXXX : An Update on a Rare Aggressive Odontogenic Tumor.

@entity5 :: ('MESH:D009369', 'Disease') :: ['Dentinogenic ghost cell tumor', 'DGCT'] @entity1 :: ('9606', 'Species') :: ['patients']
@entity5 :: (MESH:D009369,Disease) :: ['Dentinogenic Ghost Cell Tumor']
