OBJECTIVES/HYPOTHESIS: The aim of this study was to identify any possible predictive factors of lateral neck recurrence in @entity1 with @entity3557 with no ultrasonographic and/or cytological evidence of @entity1600 at time of diagnosis. The influence of lateral neck recurrence on survival was also investigated. STUDY DESIGN: Observational retrospective study. METHODS: Retrospective review of clinical records of 610 @entity1 surgically treated for @entity3557 with clinically negative lymph nodes at the Otolaryngology Unit of the Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, from January 1984 to December 2008. RESULTS: Lateral neck recurrences were ipsilateral to the @entity5 in all cases and were associated with the occurrence of more aggressive histological variants and central neck @entity3 . Lateral neck recurrences were more frequently observed in @entity1 with distant metastases and were associated with a reduced disease-specific survival. CONCLUSION: Lateral neck compartment ipsilateral to the @entity5 was the most common site of recurrence, with about half of cases appearing in the first 28 months of follow-up. In @entity1 with @entity3557 , detection of lateral neck metastases prior to first surgery is crucial to surgical planning. Aggressive histological variants and postsurgical evidence of @entity1600 from @entity3557 in central neck compartment are associated with a higher risk of lateral neck recurrence. In these @entity1 , a closer postsurgical ultrasound surveillance of the lateral neck compartments seems worthwhile. LEVEL OF EVIDENCE: 4. Laryngoscope, 2014.

Lateral neck recurrence from XXXX : Predictive factors and prognostic significance.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3557 :: ('MESH:C536915', 'Disease') :: ['papillary thyroid carcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumor'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['lymph node metastasis'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity3557 :: (MESH:C536915,Disease) :: ['papillary thyroid carcinoma']
