OBJECTIVES: We have shown that, in a randomized trial comparing adherence to different @entity14 ( @entity14 ) screening strategies, @entity1 assigned to either @entity1503 ( @entity1503 ) or given a choice between @entity1503 and colonoscopy had significantly higher adherence than those assigned to colonoscopy during the first year. However, how adherence to screening changes over time is unknown. METHODS: In this trial, 997 @entity1 were cluster randomized to one of the three screening strategies: (i) @entity1503 , (ii) colonoscopy, or (iii) a choice between @entity1503 and colonoscopy. Research assistants helped @entity1 to complete testing only in the first year. Adherence to screening was defined as completion of three @entity1503 cards in each of 3 years after enrollment or completion of colonoscopy within the first year of enrollment. The primary outcome was adherence to assigned strategy over 3 years. Additional outcomes included identification of sociodemographic factors associated with adherence. RESULTS: @entity1 assigned to annual @entity1503 completed screening at a significantly lower rate over 3 years (14%) than those assigned to colonoscopy (38%, P<0.001) or choice (42%, P<0.001); however, completion of any screening test fell precipitously, indicating the strong effect of @entity1 navigation. In multivariable logistic regression analysis, being randomized to the choice or colonoscopy group, Chinese language, homosexuality, being married/partnered, and having a non-nurse practitioner primary care provider were independently associated with greater adherence to screening (P<0.01). CONCLUSIONS: In a 3-year follow-up of a randomized trial comparing competing @entity14 screening strategies, @entity1 offered a choice between @entity1503 and colonoscopy continued to have relatively high adherence, whereas adherence in the @entity1503 group fell significantly below that of the choice and colonoscopy groups. @entity1 navigation is crucial to achieving adherence to @entity14 screening, and @entity1503 is especially vulnerable because of the need for annual testing.Am J Gastroenterol advance online publication, 3 November 2015; doi:10.1038/ajg.2015.367.

Adherence to Competing Strategies for XXXX Screening Over 3 Years.

@entity1 :: ('9606', 'Species') :: ['participants', 'patient', 'Participants', 'Patient'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['FOBT', 'fecal occult blood testing'] @entity14 :: ('MESH:D015179', 'Disease') :: ['CRC', 'colorectal cancer']
@entity14 :: (MESH:D015179,Disease) :: ['Colorectal Cancer']
