BACKGROUND: The effect of surgery on quality of life (QOL) in the early postoperative period is important in @entity30 because of the multiple surgical procedures that @entity1 undergo and the acute QOL benefits that might occur as a result of modifications of medical treatment. Earlier studies of the effect of surgery on QOL have been retrospective and assessed changes 3 to 24 months after surgery. This study prospectively assesses the effect of surgery on QOL in the early postoperative period. STUDY DESIGN: @entity1 requiring surgical management of sequelae of @entity30 were obtained from a prospectively entered database including data on QOL. Preoperative and 30-day postoperative QOL were determined in 82 @entity1 using Cleveland Global Quality of Life (CGQL) scores (range from 0 [worst] to 10 [best possible] QOL). Preoperative and postoperative scores were compared using a paired t-test to determine the significance of any change in QOL after surgery. The effect of other variables on change in QOL after surgery was assessed using the t-test or analysis of variance. Multifactor analysis of variance was used to assess the effect of several independent variables. RESULTS: Eighty-two @entity1 (41 @entity1 ) of 142 @entity1 who had had surgery (58%) had complete preoperative and 30-day postoperative scores. The incidence of complications was 23% (11% were major). There was a significant improvement in QOL 30 days after surgery as measured by CGQL (0.6 +/- 0.2 preoperative to 0.7 +/- 0.2 postoperative; mean +/- SD; p < 0.001). The mean preoperative CGQL was 0.56 +/- 0.24 and the mean improvement was 0.11 +/- 0.20 toward a better QOL. Female @entity1 (p < 0.05) and those who did not develop complications within 30 days of surgery (p < 0.05) had a significantly greater improvement in CGQL after surgery than other groups. No other factor was predictive of improved outcomes. CONCLUSIONS: QOL as measured by CGQL improves early after surgery (30 days postoperatively). Improvement in CGQL is greater in female @entity1 and @entity1 who do not develop complications in the postoperative period. It is not affected by other @entity1 characteristics, nature of disease, indication, or procedure performed. Most @entity1 who undergo surgery for @entity30 feel that surgery has helped them and would undergo surgery again.

Quality of life improves within 30 days of surgery for XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'patient'] @entity30 :: ('MESH:D003424', 'Disease') :: ["Crohn's disease"]
@entity30 :: (MESH:D003424,Disease) :: ['Crohn's disease']
