Herein we reviewed the histopathological findings in 327 consecutive surgical specimens from @entity1 with pharmaco-resistant @entity302 (PRE). Three major pathological groups (78.3% of all cases) were identified: Ammon's @entity1463 (85 cases as an isolated lesion plus 18 as one part of a dual pathology), @entity5 (94 cases), and @entity600 (77 cases). @entity5 , often associated with @entity6795 ( @entity6795 ), were all of low histological grade and included 61 @entity10053 ( @entity10053 ), 29 @entity7667 , and 4 @entity1893 ( @entity1893 ). Among the @entity600 were observed 52 @entity6795 , 13 cavernomas, 8 cortical tubers, and 4 cysts. The remaining findings consisted of 16 scars (mostly post-traumatic) and 4 Rasmussen's @entity198 . Fifty-one (15.6%) specimens contained non-specific changes, and histological samples from 215 @entity1 with presurgical implantation of electrodes revealed iatrogenic changes. All these figures are in agreement with the most recent and comparable series, and confirm the high incidence of @entity10053 that appear clearly as the most common tumoral entity in PRE. Our data also support the hypothesis of a close histogenetic relationship between @entity18961 , @entity7667 , and PXA, with a putative common origin from pluripotential progenitor @entity2280 positive cells of the subpial granular layer. As for @entity6795 , our study confirms the clinical relevance of two main subtypes: severe @entity1050 (or @entity1050 ) with neuronal cytomegaly and balloon cells, and @entity10067 with a better outcome. Eventually, this series demonstrates that most @entity1 have significant @entity75 , among which, aspects that are relevant to the diagnostic surgical pathologist are highlighted [published with a complete image database on @entity1050 -Rom].

Surgical pathology of drug-resistant partial XXXX . A 10-year-experience with a series of 327 consecutive resections.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity198 :: ('MESH:D004660', 'Disease') :: ['encephalitis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors', 'Tumors'] @entity75 :: ('MESH:D001927', 'Disease') :: ['histopathological lesions'] @entity1050 :: ('MESH:D006223', 'Disease') :: ["Taylor's type CD", 'CD'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations'] @entity6795 :: ('MESH:D054220', 'Disease') :: ['cortical dysplasias', 'CDs'] @entity1463 :: ('MESH:D012598', 'Disease') :: ['horn sclerosis'] @entity10067 :: ('MESH:C537067', 'Disease') :: ["non-Taylor's type CDs"] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy'] @entity10053 :: ('MESH:D018302', 'Disease') :: ['DNTs', 'dysembryoplastic neuroepithelial tumors'] @entity2280 :: ('947', 'Gene') :: ['CD34'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['pleomorphic xanthoastrocytomas', 'PXAs'] @entity18961 :: ('30833', 'Gene') :: ['DNT'] @entity7667 :: ('MESH:D018303', 'Disease') :: ['gangliogliomas', 'ganglioglioma']
@entity302 :: (MESH:D004827,Disease) :: ['epilepsy']
