UNASSIGNED: Vitiligo is one of the most primitive well-known @entity74 with different suggested therapies. Therefore, this study investigated the efficiency and safety of topical @entity1140 in treatment of @entity1 with @entity1694 . This study was a clinical randomized designed study pre- post-test method, has been conducted on thirty cases with @entity1694 who have referred to polyclinic and dermatology clinic. @entity1 's evaluated and demographic information recorded in designed checklist. In the next stage, the disease activity scored by @entity1694 index disease activity system. Photography and depigmentation percent has recorded before treatment and further in 4(th), 8(th), 12(th), 16(th), 20(th), and 24(th) weeks. Finally, gathered data compared through SPSS-20 software. The final sample comprised 30 @entity1 including: 12 @entity1 (40%) and 18 @entity1 (60%). The average of @entity1 's age in this study was 26/13    18/20 (2-76-year-old). Eleven @entity1 was <= 15 years old and rest was older than 15. Sixty-six lesions have funded in @entity1 that maximum has accrued on face and neck (37/87%) and trunk (21/21%). In addition, minimum of lesions is related to genitalia (9/09%). In the in 4(th), 8(th), 12(th), 16(th) weeks, improvement in face and neck had increased significantly, into the past weeks. In the 20(th) and 24(th) weeks, the improvement has increased although it was not significant enhancement. Also about trunk, in the 4(th) week the improvement does not have significant increasing in compare to the past week. In the eighth, 12(th), 16(th), 20(th), and 24(th) weeks the improvement has been increased significantly in compare to the past weeks. Although in the case of limbs and genitalia, the improvement was lower. There was no significant difference between male and females and age. Although the improvement was, slow in older @entity1 . Study results, has presented applying topical @entity1140 in @entity1694 , particularly in face and neck, could be effective and does not seen any specified adverse effects during consumption of @entity1140 , it could be effective in decreasing effects in use of corticosteroid.

Effectiveness and safety of topical XXXX in treatment of @entity1694 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'Participant', 'persons', 'men'] @entity74 :: ('MESH:D030342', 'Disease') :: ['dermatoid disorders'] @entity1694 :: ('MESH:D014820', 'Disease') :: ['vitiligo'] @entity1140 :: ('MESH:D016559', 'Chemical') :: ['tacrolimus']
@entity1140 :: (MESH:D016559,Chemical) :: ['tacrolimus']
