We describe the case of a 38-year-old male @entity1 who had @entity3052 and developed prolonged @entity1398 after induction chemotherapy. He developed @entity715 complications at multiple sites. @entity2268 of the @entity6713 plexus became exacerbated and developed into critical @entity2688 . Because the @entity1 had no human leukocyte antigen-identical sibling, we considered an alternative donor. Because of the necessity for early neutrophil recovery to resolve the critical @entity281 , we proceeded with allogeneic peripheral blood stem cell transplantation (PBSCT) from a microchimeric haploidentical sibling donor. We infused peripheral blood mononuclear cells directly into the @entity1 without cryopreservation and thawing procedures. We aimed for the contaminating granulocytes to act as a granulocyte transfusion. Actually, the neutrophils increased to 1.6 x 10(9)/L on day 1, when the @entity1 showed a temporary resolution of @entity281 . Engraftment was achieved shortly after neutropenic nadir, and @entity2132 ( @entity2132 ) has been well controlled. Although the @entity1 experiences extensive @entity2132 , he has been well as an outpatient with a 90% Karnofsky performance status score. The @entity1778 has been in complete remission for more than 1 year. These findings suggest the clinical utility of a salvage therapy with allogeneic PBSCT from a microchimeric haploidentical donor to treat @entity1778 concurrent with life-threatening @entity281 .

Successful stem cell transplantation without cryopreservation from a microchimeric haploidentical sibling for refractory XXXX complicated with critical @entity2268 and @entity2688 .

@entity1 :: ('9606', 'Species') :: ['patient'] @entity2268 :: ('MESH:D013924', 'Disease') :: ['Thrombophlebitis'] @entity2688 :: ('MESH:D002481', 'Disease') :: ['cellulitis'] @entity3052 :: ('MESH:D015470', 'Disease') :: ['acute myeloid leukemia'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1398 :: ('MESH:D009503', 'Disease') :: ['neutropenia'] @entity2132 :: ('MESH:D006086', 'Disease') :: ['GVHD', 'chronic GVHD', 'acute graft-versus-host disease'] @entity1778 :: ('MESH:D007938', 'Disease') :: ['refractory leukemia', 'leukemia'] @entity6713 :: ('MESH:D006484', 'Disease') :: ['hemorrhoidal'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombotic']
@entity3052 :: (MESH:D015470,Disease) :: ['acute myeloid leukemia']
