BACKGROUND/AIMS: The importance of lateral node dissection has not yet been fully investigated in advanced @entity5 . To evaluate @entity5 cells in perirectal and lateral lymph nodes dissection from @entity420 considered free of disease by the @entity1710 - @entity1711 test. METHODOLOGY: Fifteen @entity1 submitted to neoadjuvant therapy and surgery for @entity420 with lateral node dissection were studied, retrospectively. The paraffin blocs of the nodes were analyzed with a immunohistochemical study and multiples cross section of the nodes. RESULTS: A total of 331 lymph nodes from these 15 @entity1 were assessed, distributed as 258 perirectal nodes, 73 non perirectal, and 27 lateral nodes. The average was 22.1 lymph nodes per @entity1 . Three @entity1 out of 15 (20%) with histological negative lateral lymph node had occult @entity3 detected by pancytokeratins @entity1325 and @entity1326 . One of these cases didn't present @entity5 in the surgical specimen of the rectum. A case of positive lateral node identified by @entity1710 - @entity1711 was also identified by immunohistochemical study. CONCLUSIONS: Although we had a small number of @entity1 in the present study, lateral node dissection is important in selected cases of @entity5 . Pancytokeratins @entity1325 and @entity1326 had a potential to improve study for detection of occult node @entity3 , being helpful in @entity5 prognosis.

Evaluation of lateral lymph node XXXX in advanced @entity5 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1326 :: ('6508', 'Gene') :: ['AE3'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'rectal cancer', 'advanced cancer'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['eosin'] @entity1325 :: ('6521', 'Gene') :: ['AE1'] @entity1710 :: ('MESH:D006416', 'Chemical') :: ['hematoxylin'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity420 :: ('MESH:D000230', 'Disease') :: ['rectal adenocarcinomas', 'rectal adenocarcinoma']
@entity3 :: (MESH:D009362,Disease) :: ['metastases']
