BACKGROUND AND OBJECTIVES: @entity1663 ( @entity1663 ) is a common, non-scarring type of hair loss, affecting approximately 2.1% of the population, many modality of treatment recommended like @entity479 injection, topical Immunotherapy and several systemic therapies. The aim of this study was to compare intralesional @entity479 injection and cryotherapyoutcomes in @entity1663 . MATERIALS AND METHODS: In an analytical-descriptive study, 120 @entity1663 @entity1 treated with intralesionalsteroid injection and 120 @entity1663 @entity1 treated with cryotherapy were randomly selected. These two groups matched for location, duration and size of lesion and also matched for age and gender. From March 2011 to September 2013, the effect and complications of the therapies after 3, 6, 9 and 12 weeks were assessed and results were compared between the two groups. RESULTS: Mean age of @entity1 in @entity479 injection group was 30.2    6.8 and in cryotherapy group was 31.8    7.1. Sexual distribution in both groups was 56.7% and 43.3 % for male and female, respectively. Location of disease in 80% was in scalp and 20% was in face in both groups. The time of beginning response in @entity479 group was 4.13    2.13 weeks and in cryotherapy group was 6.14    0.29 weeks, difference between two groups was significant (P = 0.001). In term of clinical response at the end of study, in @entity479 group,20 @entity1 (16.7%) no response, 32 @entity1 (26.7%), moderate response and68 @entity1 (56.7%) had a complete response, and also in cryotherapy group was, 52 @entity1 (43.3%) no response, 40 @entity1 (33.3%) moderate response and 28 @entity1 (23.3%) had a complete response. There was significant different in complete response rate and @entity479 injection was more effective than cryotherapy(P < 0.05). CONCLUSION: As the cryotherapy isa considerable treatment of @entity1663 , alsothis study proposes intralesional injection of @entity228 , as a replacement of @entity1663 therapy; particularly the short-term complications are not significantly different.

Comparative study of intralesional XXXX injection and cryotherapy in alopecia areata.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity228 :: ('CHEBI:50858', 'Chemical') :: ['corticosteroid'] @entity1663 :: ('MESH:D000506', 'Disease') :: ['AA', 'Alopecia areata'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity479 :: (D013256,Chemical) :: ['steroid']
