OBJECTIVES: Reports of @entity5 implantation after laparoscopic procedures have raised questions regarding the safety of laparoscopic surgery when applied to @entity1 with @entity5 . Our objective was to determine if laparoscopic pelvic lymph node dissection (LPLND) had a negative effect on @entity5 behavior and clinical outcome in @entity1 with Stage T1-3, N1-3, M0 (D1) @entity263 . METHODS: Fifty-two @entity1 were retrospectively identified at four institutions who had pelvic nodes positive for metastatic @entity263 at LPLND and at least 1 year of follow-up. Operative and clinical records were reviewed to determine morbidity, adjuvant treatment, onset of hormone-resistant disease, and survival. RESULTS: During a mean follow-up of 3.1 years, there were no cases of trocar site @entity5 implantation. There were four perioperative complications, including enterotomy, @entity130 , abscess, and symptomatic lymphocele formation. There were three deaths from @entity263 (5.8%) occurring 3 to 4 years after LPLND. For the 45 @entity1 treated with early @entity342 ablation, the 5-year biochemical @entity1486 and clinical progression free rates were 45% and 55%, respectively. CONCLUSIONS: @entity5 implantation after LPLND for @entity263 was not demonstrated, even in @entity1 who developed hormone-resistant disease. LPLND in @entity1 with Stage D1 disease did not alter short-term disease progression. Longer follow-up in a larger cohort is necessary to determine if LPLND will have an impact on the 5 and 10-year disease progression and survival rates for @entity1 with Stage D1 @entity263 .

Effect of laparoscopic pelvic lymph node dissection on the natural history of D1 (T1-3, N1-3, M0) XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate adenocarcinoma', 'prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'abdominal wall tumor', 'Abdominal wall tumor', 'malignancies'] @entity342 :: ('CHEBI:50113', 'Chemical') :: ['androgen'] @entity1486 :: ('354', 'Gene') :: ['prostate-specific antigen'] @entity130 :: ('MESH:D014947', 'Disease') :: ['epigastric vessel injury']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
