PURPOSE: @entity989 ( @entity989 ) is the primary cause of @entity227 in preterm @entity1 . There are available data confirming that circulating endothelial progenitor cells (EPCs) are involved in forming the growing network of blood vessels in the developing retina. In this study we sought to explore potential relationship between concentration of circulating bone marrow-derived EPCs and development of @entity989 in prospective study. MATERIAL AND METHODS: The study groups consisted of 90 preterm (23-36 weeks of gestational age), and 52 full-term control @entity1 . EPCs were analyzed in cord blood (CB) and subsequently in peripheral blood (PB) in second and sixth week since delivery. The incidence and stage of @entity989 was prospectively documented in the preterm @entity1 . RESULTS: EPC concentration in CB was considerably higher in the preterm @entity1 developing @entity989 . In the preterm @entity1 a noticeable decrease in PB EPC concentration within six weeks of the follow up was found, whereas in full-term @entity1 EPC concentration was maintained at invariable level. Of note, in the sixth week since delivery, EPC concentration in preterm @entity1 with @entity989 was lower compared to preterm @entity1 without @entity989 . CONCLUSIONS: Increase in CB EPC concentration in preterm @entity1 , including those developing @entity989 , indicates that the circulating EPC cells contribute to the process of blood vessel formation, and their number in CB reflects the degree of @entity3465 . Impaired blood vessel formation within retina in the course of @entity989 may result from decrease in circulating EPC number observed at the sixth week since delivery.

[The role of circulating endothelial progenitor cells in the progression of XXXX of @entity3465 --a prospective study].

@entity1 :: ('9606', 'Species') :: ['infants'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual impairment'] @entity3465 :: ('MESH:C536271', 'Disease') :: ['prematurity'] @entity989 :: ('MESH:D012164', 'Disease') :: ['ROP', 'Retinopathy of prematurity']
@entity989 :: (MESH:D012164,Disease) :: ['retinopathy']
