The purpose of this study was to investigate a case of @entity6538 ( @entity6538 ) in which numerous calcifications were observed not only in the lining epithelium, but also in the cyst wall, using cytokeratins 13 (CK13), 19 ( @entity4166 ), and core binding factor a-1 ( @entity8087 ) as primary antibodies. Cells of Malassez's epithelial rest were stained as controls. Cells of the epithelial nests in the cyst wall were reactive for CK13, but their @entity4166 staining was similar to that observed in the lining epithelial cells. Calcifying nodules were reactive only for CK13. Cells of Malassez's epithelial rest were reactive for @entity4166 but not for CK13. @entity8087 positive reactivity was observed only in nuclei of spindle cells in the periodontal ligament. CK13 was positive superficial to the prickle cells. @entity4166 was positive in the basal cells of the oral mucosa. In the lining epithelium of the cyst, the expressions of CK13 and @entity4166 were similar to their immunoreactions in the oral mucosa. These results suggest that the odontogenic epithelium differentiated into squamous epithelial cells, which began as ghost cells in the @entity6538 , and that this process depended on the @entity730 of differentiated odontogenic epithelial cells, not of osteogenic cells.

A case of XXXX with numerous calcifications: immunohistochemical analysis.

@entity730 :: ('MESH:D002114', 'Disease') :: ['dystrophic calcification'] @entity8087 :: ('860', 'Gene') :: ['cbfa-1', 'Cbfa-1'] @entity4166 :: ('3880', 'Gene') :: ['CK19'] @entity6538 :: ('MESH:D018333', 'Disease') :: ['COC', 'calcifying odontogenic cyst']
@entity6538 :: (MESH:D018333,Disease) :: ['calcifying odontogenic cyst']
