OBJECTIVE: @entity121 ( @entity121 ) is increased in subjects with @entity5710 or newly diagnosed @entity6 . However, no previous studies have evaluated the relationship between the severity of @entity2998 , assessed by the presence of carotid plaques or @entity850 , and the glycemic status, assessed either by fasting @entity413 , an oral @entity413 tolerance test (OGTT) or @entity3916 levels. METHODS: Cross-sectional analysis of 1475 subjects (mean age 62 years, 44% males), randomly selected from the population. A fasting blood sample was obtained to determine @entity413 , lipids, and @entity3916 levels. An OGTT was performed in non- @entity6 subjects. Carotid @entity731 was evaluated by echo-doppler. RESULTS: A 10.5% of the population had a previous diagnosis of @entity6 . Of the 1320 non- @entity6 @entity1 , 349 (26.4%) had normal fasting @entity413 , normal @entity413 tolerance and @entity3916  <  5.7%, and were considered controls. @entity5710 was diagnosed in 850 subjects (64.4%), and @entity6 was newly diagnosed in 121 (9.2%). The prevalence of @entity1 with carotid plaques was 34.2% in controls, 45.1% in prediabetics, 64.2% in newly diagnosed @entity6 , and 72.9% in established @entity6 @entity1 . These numbers were 0.3%, 1.1%, 5.0% and 7.7% for @entity543 , respectively. In multivariate analysis, glycemic status remained significantly associated with the prevalence of carotid plaques after adjusting for age, sex, statin treatment, and cardiovascular risk factors. CONCLUSIONS: Glycemic status is associated with all grades of @entity2998 , from early signs, as demonstrated by the @entity121 , to intermediate degrees, as demonstrated by the presence of carotid plaques, to advance @entity731 , as established by the presence of @entity543 .

Carotid XXXX severity in relation to glycemic status: A cross-sectional population study.

@entity1 :: ('9606', 'Species') :: ['participants', 'patients'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetics', 'diabetic', 'diabetes'] @entity5710 :: ('MESH:D011236', 'Disease') :: ['prediabetes', 'Prediabetes'] @entity3916 :: ('c|SUB|A|1|C', 'DNAMutation') :: ['A1C'] @entity2998 :: ('MESH:D002340', 'Disease') :: ['carotid atherosclerosis'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity543 :: ('MESH:D016893', 'Disease') :: ['carotid stenosis'] @entity121 :: ('MESH:D009135', 'Disease') :: ['IMT', 'Intima-media thickness'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity731 :: (MESH:D050197,Disease) :: ['atherosclerosis']
