We investigated the relationship of @entity227 ( @entity227 ) and age-related @entity2194 with mortality in a prospective, population-based cohort study of 3,280 Malay adults aged 40-80 years between 2004-2006. @entity1 underwent a full ophthalmic examination and standardized lens and fundus photographic grading. Visual acuity was measured using logMAR chart. @entity227 was defined as presenting ( @entity939 ) and best-corrected (BCVA) visual acuity worse than 0.30 logMAR in the better-seeing eye. @entity1 were linked with mortality records until 2012. During follow-up (median 7.24 years), 398 (12.2%) @entity1 died. In Cox proportional-hazards models adjusting for relevant factors, @entity1 with @entity227 ( @entity939 ) had higher all-cause mortality (hazard ratio[HR], 1.57; 95% confidence interval[CI], 1.25-1.96) and cardiovascular (CVD) mortality (HR 1.75; 95% CI, 1.24-2.49) than @entity1 without. @entity6 ( @entity6 ) was associated with increased all-cause (HR 1.70; 95% CI, 1.25-2.36) and CVD mortality (HR 1.57; 95% CI, 1.05-2.43). @entity2994 ( @entity2994 ) was associated with @entity101 (HR 3.14; 95% CI, 1.26-7.73). No significant associations were observed between @entity231 , @entity726 and age-related @entity1020 with mortality. We conclude that @entity1 with @entity227 were more likely to die than @entity1 without. @entity6 and @entity2994 are markers of CVD mortality.

Impact of @entity227 and XXXX on Mortality: the Singapore Malay Eye Study (SiMES).

@entity1 :: ('9606', 'Species') :: ['participants', 'Participants', 'persons'] @entity2194 :: ('MESH:D005128', 'Disease') :: ['eye diseases'] @entity227 :: ('MESH:D014786', 'Disease') :: ['VI', 'visual impairment'] @entity939 :: ('CHEBI:17246', 'Chemical') :: ['PVA'] @entity101 :: ('MESH:D006973', 'Disease') :: ['increased CVD mortality'] @entity6 :: ('MESH:D003920', 'Disease') :: ['DR', 'Diabetic retinopathy'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract'] @entity2994 :: ('MESH:D012170', 'Disease') :: ['Retinal vein occlusion', 'RVO'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity1020 :: ('MESH:D008268', 'Disease') :: ['macular degeneration']
@entity2194 :: (MESH:D005128,Disease) :: ['Eye diseases']
