AIM: To evaluate recurrence rate and associated risk factors for recurrence after @entity1068 ablation (EA) in @entity1 with predominantly cystic thyroid nodules. MATERIALS AND METHODS: This observational study was approved by the Ethics Committee of the Institutional Review Board and informed consent for procedures was obtained. From April 2009 to April 2013, 107 consecutive @entity1 with predominantly cystic nodules were treated using EA. Recurrence was defined as nodules showing a residual solid portion with internal vascularity, cosmetic problems remaining, or persistent symptoms, and @entity1 who requested additional therapy to resolve their symptomatic or cosmetic problems. Delayed recurrence was defined as treated nodules that showed no recurrent features at 1 month, but showed newly developed recurrent features during the longer follow-up period. Multivariate analysis was used for variables to demonstrate the independent factors related to @entity353 . RESULTS: One month after EA, 18.7% of @entity1 (20/107) showed recurrence. Among 87 @entity1 with non-recurrence, 24.1% (21/87) showed delayed recurrence. The total recurrence rate was 38.3% (41/107). @entity1 with recurrence (n  =  41) were treated using radiofrequency ablation (n  =  28), second EA (n  =  4), and refused further treatment (n  =  9). These @entity1 responded well to repeat EA and radiofrequency ablation. Multivariate analysis demonstrated that the initial nodule volume (>20  ml; p  <  0.036) and vascularity (grade >1; p  <  0.049) were independent predictors of @entity353 at last follow-up. CONCLUSIONS: The results revealed that although EA seemed to be effective during the initial period, delayed recurrence should be considered during longer-term follow-up. The independent predictors of recurrence were initial volume (>20  ml) and vascularity.

XXXX ablation of predominantly cystic thyroid nodules: Evaluation of recurrence rate and factors related to recurrence.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol'] @entity353 :: ('MESH:D015431', 'Disease') :: ['volume reduction']
@entity1068 :: (MESH:D000431,Chemical) :: ['Ethanol']
