AIM: To evaluate potential value of Virtual Touch quantification (VTQ) of acoustic radiation force impulse (ARFI) imaging for characterising focal solid @entity8 . MATERIALS AND METHODS: Two independent operators performed 10 and five measurements of each lesion and adjacent renal cortex, respectively. Mean shear wave velocity (SWV) and shear wave velocity ratio (SWR) of histotypes were compared. RESULTS: One hundred and ninety-seven @entity8 were evaluated, including 155 @entity1358 (RCCs; 129 clear-cell RCCs [ccRCCs], 14 papillary RCCs [pRCCs], and 12 chromophobe RCCs [cRCCs]) and 42 @entity359 ( @entity359 ). The interoperator reproducibility of SWV of @entity703 and renal cortex were good (ICC=0.852, and 0.903, respectively). SWV of the renal cortex at a depth of <4  cm was significant higher than that at a depth of >4  cm. Regardless of the subtypes of @entity1358 , SWV and SWR of RCCs differed significantly from those of @entity359 (2.28  0.85 versus 1.98  0.85; 1.09  0.56 versus 0.78  0.34; p=0.045 and p<0.001, respectively). At cut-off points of SWV >1.87  m/s or SWR >0.84 to differentiate RCCs from @entity359 , the sensitivity and specificity were 47.5%, 33.2% or 47.5%, 30.2%, respectively. When the subtypes of RCCs were taken into account, SWV and SWR of ccRCCs were significantly higher than those of pRCCs, cRCCs, and @entity359 , while there was no significant difference among the latter. With SWV >1.98  m/s or SWR >0.80 as the cut-off point to differentiate ccRCCs from other @entity703 , the sensitivity and specificity were 69.8%, 65% or 76.8%, 73.4%, respectively. CONCLUSION: The ARFI technique offers additional information regarding @entity703 elasticity with good reproducibility. SWV and SWR are potential biomarkers in this setting, helping to differentiate ccRCC from other @entity703 histotypes.

Virtual Touch quantification using acoustic radiation force impulse (ARFI) technology for the evaluation of focal solid XXXX : preliminary findings.

@entity1358 :: ('MESH:D002292', 'Disease') :: ['renal cell carcinomas', 'RCC'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal lesions'] @entity359 :: ('MESH:D018207', 'Disease') :: ['angiomyolipomas', 'AMLs'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal tumour', 'renal tumours']
@entity8 :: (MESH:D007674,Disease) :: ['renal lesions']
