UNASSIGNED: @entity2835 (formerly known as @entity2835 and now named primary @entity253 ) is a disease with a wide range of severity and variable rate of progression. The diagnosis of advanced @entity1575 / @entity82 portends an increased risk of liver-related morbidity and mortality. Because of its invasiveness, liver biopsy tends to be replaced by non-invasive tools for assessing @entity1575 , making prognosis and optimising risk stratification for selection of @entity1 , requiring new medical approaches. Many direct or indirect biomarkers have been found to correlate with the severity of @entity1575 in @entity2835 . They are easy to use but lack sensitivity and reproducibility in individuals with early stage disease. Three main radiologic approaches are currently proposed to assess @entity1575 : vibration controlled transient elastography (VCTE), acoustic radiation force impulse and magnetic resonance elastography. Data using VCTE are available only for the longitudinal evaluation of @entity1575 and prognosis in @entity2835 . VCTE outperformed all other non-invasive current surrogate markers of @entity1575 in @entity2835 . Because of its high acceptability and its ability to predict @entity99 , VCTE could be a useful tool to help allocate cirrhotic @entity1 into different categories of risk. None of the radiologic and serum markers have a perfect accuracy in studies so far published. Concordance between VCTE and serum biomarkers is a prerequisite for a correct prognosis assessment in individuals in clinical practice.

Non-Invasive Assessment of Liver Fibrosis Progression and Prognosis in Primary XXXX .

@entity2835 :: ('MESH:D008105', 'Disease') :: ['PBC', 'primary biliary cirrhosis'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity1575 :: ('MESH:D008103', 'Disease') :: ['liver fibrosis'] @entity253 :: ('MESH:D001660', 'Disease') :: ['biliary cholangitis'] @entity99 :: ('MESH:D056486', 'Disease') :: ['hepatic decompensation']
@entity253 :: (MESH:D001660,Disease) :: ['Biliary Cholangitis']
