Calcification of the middle cerebral artery (MCA) is uncommon in the healthy elderly. Whether @entity730 of the MCA is associated with cerebral @entity385 remains undetermined. We intended to investigate the association using Agatston @entity460 scoring of the MCA. This study retrospectively included 354 subjects with @entity385 in the MCA territory and 1518 control subjects who underwent computed tomography (CT) of the brain. We recorded major known risk factors for @entity385 , including age, gender, @entity101 , @entity6 , smoking, @entity407 , and @entity28 , along with the MCA @entity460 burden, measured with the Agatston @entity460 scoring method. Univariate and modified logistic regression analyses were performed to examine the association between the MCA @entity730 and @entity385 .The univariate analyses showed significant associations of @entity385 with age, @entity101 , @entity6 , smoking, total MCA Agatston score, and the presence of @entity730 on both or either side of the MCA. Subjects with the presence of MCA @entity730 on both or either side of the MCA were 8.46 times (95% confidence interval, 4.93-14.53; P<0.001) more likely to have a @entity2500 after adjustment for the major known risk factors, including age, @entity101 , @entity6 , and smoking. However, a @entity729 reflected by the Agatston score was not associated with higher risk of MCA @entity385 after adjustment for the confounding factors and presence of MCA @entity730 . These results suggest that MCA @entity730 is associated with @entity385 in the MCA territory. Further prospective studies are required to verify the clinical implications of the MCA @entity730 .

Middle Cerebral @entity729 : Association With XXXX .

@entity407 :: ('MESH:D006949', 'Disease') :: ['hyperlipidemia'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity2500 :: ('MESH:D020244', 'Disease') :: ['cerebral infarct than subjects without MCA calcification'] @entity730 :: ('MESH:D002114', 'Disease') :: ['calcification'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity729 :: ('MESH:D061205', 'Disease') :: ['higher degree of MCA calcification'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['Ischemic Stroke']
