Perfluorochemicals provide a biologically inert system for @entity26 transport to tissue. The purpose of the present study was to determine if a simple clean-up procedure could reverse the endocrine @entity137 of a commercially produced perfluorochemical emulsion, @entity37553 -E.T. The clean-up procedure consisted of a combined resin and dialysis treatment. The endocrine @entity137 of the untreated and treated perfluorochemical emulsions was tested by determining their effect on @entity251 secretion by @entity35 testes perfused in vitro. @entity35 testes perfused with untreated @entity37553 -E.T. secreted low amounts of @entity251 . However, the treated @entity37553 -E.T. was an effective and nontoxic @entity26 carrier for testes perfused in vitro. The results are significant because they suggest that the endocrine @entity137 of @entity37553 -E.T. is caused by toxic contaminants and not the perfluorochemicals. Additional experiments revealed that the @entity1388 ion may be the primary toxic contaminant of @entity37553 -E.T. The data support the efficacy of perfluorochemicals as @entity26 carriers for @entity35 testes perfused in vitro.

Reversal of the endocrine XXXX of commercially produced perfluorochemical emulsion.

@entity251 :: ('MESH:D013739', 'Chemical') :: ['testosterone'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity37553 :: ('MESH:C008807', 'Chemical') :: ['Oxypherol'] @entity35 :: ('10116', 'Species') :: ['rat', 'Rat'] @entity1388 :: ('MESH:D005459', 'Chemical') :: ['fluoride']
@entity137 :: (MESH:D064420,Disease) :: ['toxicity']
