Based on the good results of re-irradiation plus @entity221 in @entity0 recurrences on the chest wall, it was decided to offer similar treatment to a @entity1 with recurrent metastatic @entity0 in the orbital region. A female @entity1 was diagnosed in 1997 with @entity0 stage T4N0M0. She was treated with six neo-adjuvant chemotherapy courses and mastectomy, followed by hormonal treatment. In December 1998, she was diagnosed with @entity3 in the medial upper quadrant of the left orbit. This was excised, followed by 40 Gy radiotherapy. Nine months later, the @entity5 had recurred in the left orbit at the margin of the radiotherapy field. This again was treated with surgery, followed by 30 Gy radiotherapy. Two months thereafter, the @entity5 progressed and hormonal therapy was changed, without an effect on the @entity5 . Screening gave no evidence of @entity5 activity elsewhere. The @entity1 preferred treatment with re-irradiation plus @entity221 to a surgical approach. Eight fractions of 4 Gy were given in 4 weeks, combined with once weekly @entity221 . One week after treatment, the @entity5 had regressed completely. The @entity1 died 22 months following treatment. Until last follow-up, a few weeks before death, the @entity1 mentioned a dry left eye for which she used eyedrops, an unchanged vision and no further difficulties. On examination, there was epilation of the eyelids, a slight conjunctival @entity4 , no subcutaneous @entity82 and no evidence of @entity5 regrowth. For this @entity1 , a surgical approach would have resulted in @entity735 . @entity137 of re-irradiation plus @entity221 might lead to either a @entity1018 or a delayed @entity735 due to treatment-induced @entity137 . The chosen local treatment resulted in a very good palliative effect, which lasted for the @entity1 's remaining lifetime of 22 months.

Re-irradiation and XXXX for recurrent @entity0 in the orbital region: a case report.

@entity1 :: ('9606', 'Species') :: ['patient'] @entity1018 :: ('MESH:D054062', 'Disease') :: ['loss of vision'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity', 'Toxicity'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['eyelid tumour', 'tumour'] @entity4 :: ('MESH:D004487', 'Disease') :: ['oedema'] @entity735 :: ('MESH:D005124', 'Disease') :: ['loss of her left eye', 'loss of the left eye'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastatic disease'] @entity221 :: ('MESH:D005334', 'Disease') :: ['hyperthermia']
@entity221 :: (MESH:D005334,Disease) :: ['hyperthermia']
