BACKGROUND: @entity698 can be treated laparoscopically, but this approach is associated with a higher rate of @entity6177 . Pneumoperitoneum impairs the clearance of bacteria from the peritoneal cavity in experimental models of @entity298 . The aim of this study was to investigate the effects of intra-abdominal gas insufflation on bacterial growth in a @entity35 model. MATERIALS AND METHODS: The effects of intraperitoneal insufflation with different gases and a gasless model on bacterial proliferation in a setting of @entity526 -induced experimental @entity298 were studied in a @entity35 model. Saline (0.25 mL) was given intraperitoneally to six @entity35 male @entity35 as the sham group. @entity526 (1.5 x 10(9) cfu/mL per kilogram) was injected intraperitoneally into to 24 @entity35 . Microorganism counts were taken after 8 hours, and @entity35 were divided into three groups: group 1, @entity515 insufflation; group 2, @entity3727 insufflation; and group 3, no insufflation. Microorganism counts were repeated 8 hours after the procedure (at 16 hours postinjection). RESULTS: The difference in microorganism counts between 8 and 16 hours were significant in the @entity515 and @entity3727 insufflation groups (P < 0.05) but not in the group without @entity516 . CONCLUSIONS: Abdominal insufflation may promote intra-abdominal bacterial growth or decrease intra-abdominal bacterial clearance.

Effect of abdominal insufflation on bacterial growth in experimental XXXX .

@entity3727 :: ('CHEBI:17045', 'Chemical') :: ['N2O'] @entity698 :: ('MESH:D001064', 'Disease') :: ['Perforated appendicitis'] @entity6177 :: ('MESH:D018784', 'Disease') :: ['intra-abdominal abscess'] @entity515 :: ('CHEBI:29334', 'Chemical') :: ['CO2'] @entity35 :: ('10116', 'Species') :: ['rat', 'Wistar', 'rats'] @entity516 :: ('MESH:D011027', 'Disease') :: ['pneumoperitoneum'] @entity298 :: ('MESH:D010538', 'Disease') :: ['peritonitis'] @entity526 :: ('562', 'Species') :: ['Escherichia coli']
@entity298 :: (MESH:D010538,Disease) :: ['peritonitis']
