@entity15 ( @entity15 ) is a debilitating disease commonly attributed to degradation of white matter myelin. Symptoms include @entity1295 , as well as problems associated with vision and movement. Although @entity62 are observed routinely in @entity1 undergoing MRI scans, such measures are often a poor predictor of disease severity. For this reason, it is instructive to measure associated changes in brain function. Widespread white-matter demyelination may lead to delays of propagation of neuronal activity, and with its excellent temporal resolution, magnetoencephalography can be used to probe such delays in controlled conditions (e.g., during a task). In healthy subjects, responses to visuomotor tasks are well documented: in motor cortex, movement elicits a localised decrease in the power of @entity5357 (event-related beta desynchronisation) followed by an increase above baseline on movement cessation (post-movement beta rebound (PMBR)). In visual cortex, visual stimulation generates @entity101 . In this study, we use a visuomotor paradigm to measure these responses in @entity15 @entity1 and compare them to age- and gender-matched healthy controls. We show a significant increase in the time-to-peak of the PMBR in @entity1 which correlates significantly with the symbol digit modalities test: a measure of information processing speed. A significant decrease in the amplitude of @entity227 in @entity1 is also seen. These findings highlight the potential value of electrophysiological imaging in generating a new understanding of visual disturbances and abnormal motor control in @entity15 @entity1 . Hum Brain Mapp, 2017.    2017 The Authors @entity1 Brain Mapping Published by Wiley Periodicals, Inc.

Abnormal task driven neural oscillations in XXXX : A visuomotor MEG study.

@entity1 :: ('9606', 'Species') :: ['patients', 'Human'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual gamma oscillations'] @entity101 :: ('MESH:D006973', 'Disease') :: ['increased gamma oscillations'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity5357 :: ('MESH:D012497', 'Disease') :: ['beta band oscillations'] @entity62 :: ('MESH:D056784', 'Disease') :: ['areas of demyelination in white matter'] @entity15 :: ('MESH:D009103', 'Disease') :: ['Multiple sclerosis', 'MS']
@entity15 :: (MESH:D009103,Disease) :: ['multiple sclerosis']
