OBJECTIVE: To evaluate the impact of an emergency medical service protocol with reduced @entity3175 dose on the intubation rate of @entity1 with @entity410 activity treated by emergency medical service personnel and to evaluate the short-term outcome comparing 2 emergency medical service treatment protocols. METHODS: Retrospective review of the emergency medical service and hospital databases of @entity1 0-18 years with @entity410 activity. Prior to January 1996, the county emergency medical service protocol recommended a @entity3175 dose of 0.2-0.5 mg/kg i.v. or pr for termination of @entity410 activity (group 1). As of January 1996, the @entity3175 dose was reduced to 0.05-0.1 mg/kg i.v. or pr (group 2). Demographics, emergency medical service and emergency department interventions, and disposition data were abstracted. RESULTS: 1516 subjects met the enrollment criteria: 1003 (66%) in group 1 and 513 (34%) in group 2. Emergency medical service administered @entity3175 to 288 subjects: 189 (19%) in group 1 and 99 (19%) in group 2. Twenty (7%) of all treated subjects required intubation: 19 in group 1 and 1 in group 2 (relative risk 9.7, 95% CI 1.30-72.5). Mean @entity3175 dose was 0.17 mg/kg in group 1 and 0.13 mg/kg in group 2 (mean difference 0.04, 95% CI 0.02-0.06). No significant difference in the requirement for repeated anticonvulsant dose, complications, or emergency department interventions was noted. However, hospital admission rate was lower in group 2 (rate difference 0.06, 95% CI 0.01-0.11). CONCLUSIONS: Our study demonstrated a reduction in intubation rate and a need for hospitalization in the reduced @entity3175 dose emergency medical service protocol. The reduction in the @entity3175 dose was effective in terminating the @entity410 activity and did not increase the risk of adverse events.

The short-term outcome of XXXX management by prehospital personnel: a comparison of two protocols.

@entity1 :: ('9606', 'Species') :: ['children'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure'] @entity3175 :: ('MESH:D003975', 'Chemical') :: ['diazepam']
@entity410 :: (MESH:D012640,Disease) :: ['seizure']
