We evaluated the risk assessment value of a commercial cardiac troponin (cTn; Ortho Vitros ECi, Ortho-Clinical Diagnostics, Raritan, NJ) I assay in @entity1 with symptoms of @entity741 suggestive of @entity1187 and compared findings with those for a commercial @entity10020 assay in the same population. The cTn levels were measured by both assays in plasma samples from 273 @entity1 during 24 hours after admission. Baseline and maximum concentrations were used for risk stratification; cutoffs were the 99th percentile and 10% coefficient of variation. End points were all-cause @entity204 and @entity299 within 60 days. Relative risks (RRs) were estimated using Cox proportional hazards regression models and @entity22605 . RRs of @entity299 and @entity204 were significantly higher with increased baseline and maximum concentrations using either @entity6949 cutoff. The respective mortality rates for baseline @entity6949 of more than 0.08 microgram/L vs 0.08 microgram/L or less were 17.4% vs 2.9% (P = .001); cardiac event rates were 11.5% vs 3.6% (P = .03). Exclusion of @entity1 with ST-segment elevation had no significant effect on rates for either assay. Mortality was higher in the intermediate (0.09-0.2 microgram/L) than in the low (< or = 0.08 microgram/L) group for @entity6949 , with directionally similar results for @entity10020 . Our findings validate the Ortho @entity6949 assay as a risk stratification biomarker in @entity1 with symptoms of @entity741 .

Prognostic value of the Ortho Vitros cardiac troponin I assay in @entity1 with symptoms of XXXX . Risk stratification using European Society of Cardiology/American College of Cardiology recommended cutoff values.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndrome'] @entity6949 :: ('7137', 'Gene') :: ['cTnI'] @entity10020 :: ('7139', 'Gene') :: ['cTnT'] @entity22605 :: ('MESH:C538012', 'Disease') :: ['Kaplan-Meier curves'] @entity741 :: ('MESH:D017202', 'Disease') :: ['myocardial ischemia'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac events'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity741 :: (MESH:D017202,Disease) :: ['myocardial ischemia']
