OBJECTIVES: The aim of the study was to investigate if the feline vomeronasal organ (VNO) can be affected by inflammatory lesions and if these changes are associated with behavioural alterations. METHODS: VNOs from 20 @entity468 were sampled during necropsy, submitted for routine tissue processing and stained with @entity6175 and @entity1711 for histopathological evaluation. Of the 20 @entity468 , data on the presence of @entity146 towards @entity468 or @entity1 were collected by questionnaire survey at the point of @entity204 . Inflammatory lesions were classified depending on the duration of the process as acute or chronic, both in @entity7944 ( @entity7944 ) and in @entity6363 ( @entity6363 ). Fisher's exact test was used to compare VNO @entity32 with behavioural data. RESULTS: The @entity7944 was inflamed in 11/20 VNOs (55%) while the @entity6363 was inflamed in 13/20 (65%). Overall, the VNO was affected by @entity32 in 14/20 (70%) @entity468 , and all the lesions were classified as chronic. Five out of 20 @entity468 (25%) had documented intraspecific @entity146 and 8/20 (40%) had shown @entity146 towards @entity1 . Fisher's exact test showed a statistically significant correlation between @entity32 of the @entity7944 and intraspecific @entity146 (P = 0.038). No statistically correlations were observed between @entity7944 @entity32 and @entity146 towards @entity1 and between @entity6363 @entity32 and @entity146 towards @entity468 or @entity1 . CONCLUSIONS AND RELEVANCE: Our results show, for the first time, the existence of vomeronasalitis in animals and its possible association with intraspecific @entity146 . The inflammatory microenvironment could impair @entity7944 functionality, causing intraspecific communication alterations, probably through a reduction in chemical communication action and perception. Owing to the pivotal role of the VNO in the social life of @entity468 and other species, this report provides a rationale to further investigate this disease in relation to a variety of @entity74 .

Pathology and behaviour in feline medicine: investigating the link between vomeronasalitis and XXXX .

@entity1 :: ('9606', 'Species') :: ['humans'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity146 :: ('MESH:D001523', 'Disease') :: ['aggression', 'aggressive behaviours'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['eosin'] @entity6363 :: ('MESH:C537845', 'Disease') :: ['non-sensory epithelium', 'NSE'] @entity7944 :: ('MESH:C536309', 'Disease') :: ['VNSE', 'vomeronasal sensory epithelium'] @entity74 :: ('MESH:D030342', 'Disease') :: ['behavioural disorders'] @entity6175 :: ('CHEBI:5601', 'Chemical') :: ['haematoxylin'] @entity468 :: ('9685', 'Species') :: ['cats'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity146 :: (MESH:D001523,Disease) :: ['aggression']
