OBJECTIVE: To analyze the variables determining morbidity, mortality and outcome in subjects with @entity867 treated at a single center over a 10-year period. METHODS: A retrospective study was conducted on a series of 59 @entity1 with @entity867 surgically treated with stereotactically guided aspiration or open craniotomy excision. Such variables as age, gender, clinical presentation, number of days to diagnosis, location, number of lesions, predisposing factors, mechanism of @entity281 , etiological agent, and therapy were analyzed independently. Complications were defined as any deviation from the normal postoperative course occurring within 30 days of surgery, and classified according to a four-point gradual severity scale. Postoperative outcome was appraised through the Glasgow Outcome Scale (GOS) 6 months after surgery, 0-4 points were considered poor outcome and 5 points good outcome. RESULTS: Eighty abscesses were diagnosed and surgically managed in 59 @entity1 . The mean age was 44.69 years (range: 0.16-77); 59.3% were female. The median number of days to diagnosis was 7. Most frequent clinical presentations included @entity221 (52.5%), @entity10 (42.4%), and focal @entity51 (39%). Mechanism of @entity281 was mainly hematogenous spread (32.2%). Stereotactically guided aspiration was the treatment of choice for 74.6% of the @entity1 , whereas 25.4% of the cases were managed through open craniotomy excision. Outcome was favorable in 81.35% (n = 48) of the subjects. General morbidity was 27.1%, and mortality stood at 10.16%. Out of a total 38.98% (n = 23) of complications, two-thirds were due to medical causes. The analysis of variables revealed that only age (p = 0.02), immunosuppression (OR 5.83; p = 0.012) and hematogenous spread (p < 0.01) were associated with poor outcomes. CONCLUSIONS: Immunosuppression, hematogenous spread and advanced age were predictors of poor prognosis. Most of the complications following @entity867 management were not directly related to surgery or surgical technique.

Supratentorial and infratentorial XXXX : surgical treatment, complications and outcomes--a 10-year single-center study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurologic deficits'] @entity10 :: ('MESH:D006261', 'Disease') :: ['headache'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity867 :: ('MESH:D001922', 'Disease') :: ['brain abscess', 'brain abscesses']
@entity867 :: (MESH:D001922,Disease) :: ['brain abscesses']
