OBJECTIVE: To determine whether @entity28 is a potential risk factor of primary @entity5254 (CSFR). DESIGN: Retrospective study. SETTING: University hospital. @entity1 AND METHODS: The clinical data of 79 @entity1 diagnosed with CSFR who had been treated at our hospital between 1991 and 2001 were assessed. The data of 61 (77%) of 79 cases were complete and could be used for this study. @entity1 were segregated according to the cause of their CSFR: 21 (34%) due to head @entity130 , 14 (23%) due to previous surgery, 7 (11%) due to @entity600 , and 2 (3%) due to @entity5 adjacent to the anterior cranial fossa. Of the 61 subjects, 17 (28%) had CSFR without any detectable reason. This group was therefore designated as primary spontaneous CSFR. The body mass indexes (BMIs) of all @entity1 were compared and statistically evaluated. RESULTS: The mean BMI (calculated as weight in kilograms divided by the square of height in meters) of the 17 @entity1 with primary spontaneous CSFR was 34.87, which was significantly higher (P<.001) than the mean BMI of the other 44 @entity1 (28.53). The mean BMI of the group of @entity1 with CSFR due to previous surgery or @entity130 was significantly lower than the BMI of the group with primary spontaneous CSFR (P<.003), whereas in relation to the group afflicted with @entity5 and @entity600 , only a tendency (P<.28) was found. CONCLUSION: Our data suggest that @entity28 @entity1 are at an increased risk to develop primary spontaneous CSFR.

XXXX as a risk factor for primary spontaneous rhinoliquorrhea.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese', 'obesity'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity600 :: ('MESH:D000014', 'Disease') :: ['malformations', 'congenital malformation'] @entity5254 :: ('MESH:D002559', 'Disease') :: ['spontaneous cerebrospinal fluid rhinorrhea'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity28 :: (MESH:D009765,Disease) :: ['Obesity']
