UNASSIGNED: Objective Sex differences in the association of HbA1c and @entity65 ( @entity65 ) risk remain controversial. We examined @entity65 risk profile in both HbA1c-defined @entity6 and nondiabetic @entity1 and @entity1 . Methods We conducted a cross-sectional analysis of 7139 Chinese adults using data from the China Health and Nutrition Survey 2009. Results HbA1c-defined nondiabetic @entity1 have a more favorable @entity65 risk profile than female counterparts. However, HbA1c-defined @entity6 @entity1 have higher levels of @entity412 , low-density lipoprotein (LDL)- @entity165 , and @entity412 /high-density lipoprotein (HDL)- @entity165 and lower levels of HDL- @entity165 , be more @entity1144 as indicated by visceral adiposity index (VAI) and lipid accumulation product (LAP), and more insulin resistant as assessed by the @entity1674 and @entity413 index (TyG) than @entity4051 c-defined @entity6 @entity1 . Furthermore, HbA1c-defined @entity6 @entity1 showed greater relative differences in ferritin than @entity6 @entity1 when compared with their nondiabetic counterparts. Statistically signi   cant sex by HbA1c-defined @entity6 status interactions were observed for @entity412 , LDL- @entity165 , HDL- @entity165 , @entity412 /HDL @entity165 , VAI, LAP, TyG, and ferritin (all ps   <   0.05). Consideration of VAI or homeostasis model assessment of insulin resistance or both failed to eliminate the sex differences in the associations between @entity6 and these @entity65 risk factors. Conclusions @entity1 who progressed from HbA1c-defined nondiabetes to HbA1c-defined @entity6 have greater metabolic deteriorations and put on more visceral adiposity than @entity1 . Key messages HbA1c-defined nondiabetic @entity1 have a more favorable @entity65 risk profile than female counterparts. @entity1 have to undergo a greater metabolic deterioration to develop HbA1c-defined @entity6 than do @entity1 . @entity1 have to put on more visceral adiposity to develop HbA1c-defined @entity6 than do @entity1 .

Sex differences in the effect of HbA1c-de   ned @entity6 on a wide range of XXXX risk factors.

@entity1 :: ('9606', 'Species') :: ['women', 'Men', 'men'] @entity4051 :: ('3039', 'Gene') :: ['HbA1'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic', 'diabetes'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity1144 :: ('MESH:D056128', 'Disease') :: ['visceral obese'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular disease']
