UNASSIGNED: In constructed wetlands micropollutants can be removed from water by phytoremediation. However, micropollutant uptake and metabolism by plants here is poorly understood due to the lack of good analytical approaches. Reported herein is the first methodology developed and validated for the multi-residue determination of 81 micropollutants (pharmaceuticals, personal care products and illicit drugs) in the emergent macrophyte @entity34688 . The method involved extraction by microwave accelerated extraction (MAE), clean-up using off-line solid phase extraction and analysis by ultra-high-performance liquid chromatography tandem mass spectrometry. Development of the MAE method found the influence of studied variables on micropollutant recovery to be: extraction temperature  >  sample mass  >  solvent composition. Validation of the developed extraction protocol revealed method recoveries were in the range 80-120% for the majority of micropollutants. Method quantitation limits (MQLs) were generally <5  ng  g(-1) dry weight demonstrating the sensitivity of the methodology. Application of the method to @entity34689 from a constructed wetland used to treat trickling filter effluent found 17 micropollutants above their MQL, up to concentrations of 200  ng  g(-1). Other than uptake, the presence of several metabolites ( @entity2049 10,11 @entity4299 , @entity21553 , @entity54880 , @entity60931 and @entity38141 ) indicated metabolism within the plant may also occur. This new analytical methodology will enable a process mass balance of the constructed wetland to be attained for the first time, and thus help understand the role of phytoremediation in micropollutant removal by such systems.

Multi-residue determination of micropollutants in XXXX from constructed wetlands using microwave assisted extraction and ultra-high-performance liquid chromatography tandem mass spectrometry.

@entity38141 :: ('MESH:C033419', 'Chemical') :: ['norketamine'] @entity34689 :: ('1396451', 'Species') :: ['P.  australis'] @entity4299 :: ('CHEBI:32955', 'Chemical') :: ['epoxide'] @entity21553 :: ('MESH:C086816', 'Chemical') :: ['desvenlafaxine'] @entity54880 :: ('MESH:C010724', 'Chemical') :: ['2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine'] @entity60931 :: ('MESH:C080579', 'Chemical') :: ['N-desmethyltramadol'] @entity2049 :: ('MESH:D002220', 'Chemical') :: ['carbamazepine'] @entity34688 :: ('29695', 'Species') :: ['Phragmites australis']
@entity34688 :: (29695,Species) :: ['Phragmites australis']
