BACKGROUND: A 64-year-old @entity1 was admitted to our hospital with significant @entity353 and symptoms of @entity1295 . He had normocytic @entity417 and @entity1398 in peripheral blood. MATERIAL AND METHODS: Further haematological and endocrinological investigations were performed. RESULTS: Bone marrow aspiration and biopsy showed @entity6349 . Immunophenotyping and cytogenetics did not provide evidence of primary @entity66 . Endocrinological testing demonstrated secondary @entity1887 . Magnetic resonance imaging of the sella turcica showed an @entity4776 . @entity701 substitution eliminated the symptoms of the @entity1 and normalised his peripheral blood values. The disturbed maturity and @entity509 of the bone marrow were also normalised. INTERPRETATION: Normalisation of haematopoiesis after @entity701 substitution indicates that @entity701 plays an important role in the regulation of haematopoiesis. @entity4776 with isolated ACTH @entity701 deficiency is a very rare cause of disturbed haematopoiesis.

[ XXXX and @entity1398 in primary @entity4776 ].

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anaemia'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity66 :: ('MESH:D004194', 'Disease') :: ['haematological disease'] @entity1887 :: ('MESH:D000309', 'Disease') :: ['adrenal insufficiency'] @entity1295 :: ('MESH:D005221', 'Disease') :: ['fatigue'] @entity4776 :: ('MESH:D004652', 'Disease') :: ['empty sella', 'Primary empty sella syndrome'] @entity509 :: ('MESH:C538429', 'Disease') :: ['hypoplasia'] @entity1398 :: ('MESH:D009503', 'Disease') :: ['absolute neutropenia'] @entity701 :: ('MESH:D006854', 'Chemical') :: ['Cortisol', 'cortisol'] @entity6349 :: ('MESH:D004416', 'Disease') :: ['dysplastic signs']
@entity417 :: (MESH:D000740,Disease) :: ['Anemia']
