BACKGROUND: We investigated the risk factors of the regional @entity1600 ( @entity1600 ) recurrence in @entity3557 ( @entity3557 ) @entity1 underwent thyroidectomy and neck dissection according to the clinicopathologic features, preoperative clinical nodal status and the recurrence in previously dissected or undissected compartment of the neck. METHODS: A retrospective analysis was performed on 297 @entity1 who underwent total thyroidectomy and @entity1600 dissection between 2004 and 2010. @entity1 with and without regional recurrence were compared by the various clinicopathological factors. Recurrence-free survival rates were estimated by the Kaplan-Meier and Cox regression method. RESULTS: With a median follow-up of 53months, 22 (7.4%) @entity1 developed regional @entity1600 recurrence. Initial @entity1600 @entity3 and @entity5 size    1cm were independent predictive factors for regional recurrence. In @entity1 without preoperative clinical @entity1600 , @entity5 size    1cm and extrathyroidal extension were significant risk factors for regional recurrence. In cases with preoperative clinical @entity1600 , there was no specific significant factor for recurrence. @entity5 size    1cm, capsular invasion, extrathyroidal extension, and lymphovascular invasion were significant risk factors of regional recurrence in previously dissected compartments. @entity5 size    1cm and extrathyroidal extension were significant predictive factors of regional recurrence in previously undissected compartments. CONCLUSIONS: @entity5 size and @entity1600 @entity3 were independent predictors of regional @entity1600 recurrence in @entity3557 @entity1 after total thyroidectomy and central neck dissection. @entity1 with @entity5 size >1cm or extrathyroidal extension were more likely to have @entity5 recur both within the previously dissected field as well as the un-dissected compartments.

Recurrence in regional lymph nodes after total thyroidectomy and neck dissection in XXXX with @entity3557 .

@entity3557 :: ('MESH:C536915', 'Disease') :: ['PTC', 'papillary thyroid cancer'] @entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Tumor'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['LN', 'lymph node'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity1 :: (9606,Species) :: ['patients']
