Donor-derived @entity364 can be associated with severe complications in transplant recipients. Donor-derived @entity7553 has been described in kidney transplant recipients where contamination of the preservation fluid (PF) was a commonly proposed source. In liver transplantation, these @entity364 have been less explored. The aim of this study was therefore to determine the incidence and clinical relevance of Candida contamination of preservation fluid in the context of liver transplantation. A 5-year (2008-2012) retrospective multicentre study involving six French liver transplantation centers was performed to determine the incidence of Candida PF contamination. Postoperative clinical features, outcomes in recipients, and risk factors for Candida-related complications of liver transplantation were studied. Candida sp. was isolated from 28 of 2107 preservation fluid samples (1.33%). @entity5132 was the most common @entity375 (n  =  18, 64%). Twenty-two recipients (78.5%) received antifungal therapy (echinocandins in 68%) for 7-37  days. Eight @entity1 developed @entity375 -related complications (28.6%) including hepatic @entity438 (n  =  6) and @entity298 (n  =  2). The 1-year mortality rate among @entity1 after a @entity375 -related complication was 62.5%. The incidence of Candida PF contamination was low, but was associated with @entity260 and high mortality. Close radiological follow-up may enable early recognition of the arterial complications associated with PF contamination by Candida.

XXXX after Candida preservation fluid contamination in liver transplant recipients.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity260 :: ('MESH:D011183', 'Disease') :: ['dramatic postoperative complications'] @entity7553 :: ('MESH:D002177', 'Disease') :: ['candidiasis'] @entity5132 :: ('5476', 'Species') :: ['Candida albicans'] @entity364 :: ('MESH:D009181', 'Disease') :: ['fungal infections'] @entity375 :: ('4932', 'Species') :: ['yeast'] @entity298 :: ('MESH:D010538', 'Disease') :: ['Candida peritonitis'] @entity438 :: ('MESH:D002532', 'Disease') :: ['artery aneurysms']
@entity364 :: (MESH:D009181,Disease) :: ['Fungal complications']
