Sera from @entity1 with @entity31 (51), @entity30 (30), @entity3749 (13), untreated @entity66 (11), @entity1744 (24), and sera from 38 healthy control subjects were tested for antibodies to the principal @entity291 's milk proteins-casein, alpha-lactalbumin, and beta-lactoglobulin. The red-cell-linked antigen-antiglobulin reaction was used to determine the titres of direct agglutinating antibodies and IgA and IgG incomplete antibodies. Apart from @entity1 with @entity66 , direct agglutinating antibodies were found infrequently and then in low titres. Approximately 50% of subjects had low titres of IgA and IgG antibodies. However, the titres found in sera from @entity1 with @entity31 did not differ from those found in the control subjects or in @entity1 with @entity30 , @entity3749 , or @entity1744 . @entity1 with untreated @entity66 frequently had high antibody titres to the milk proteins. In all subjects tested, incomplete antibodies of IgA or IgG immunoglobulin class occurred with equal frequency. The frequent occurrence in adults of low titres of antibodies to the milk proteins may be due to continued absorption of minute amounts of protein. Absorption of allergens may be facilitated by @entity16 , such as that of @entity66 , with stimulation of antibody production. At the present time, however, there is little evidence to suggest that @entity6132 is a factor in the aetiology of @entity31 .

Circulating antibodies to XXXX 's milk proteins in @entity31 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity291 :: ('9913', 'Species') :: ['cow'] @entity66 :: ('MESH:D004194', 'Disease') :: ['coeliac disease', 'adult coeliac disease'] @entity6132 :: ('MESH:D016269', 'Disease') :: ['milk allergy'] @entity16 :: ('MESH:D009422', 'Disease') :: ['mucosal damage'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis'] @entity3749 :: ('MESH:D007787', 'Disease') :: ['hypolactasia'] @entity1744 :: ('MESH:D043183', 'Disease') :: ['irritable colon syndrome'] @entity30 :: ('MESH:D003424', 'Disease') :: ["Crohn's disease"]
@entity291 :: (9913,Species) :: ['cow']
