OBJECTIVE: To study the perinatal differences of full-term newborn @entity1 with perinatal @entity1763 in relation to their neurologic manifestations (postasphyctic @entity75 ). MATERIAL AND METHODS: Prospective epidemiologic study over perinatal @entity1763 in full-term @entity1 born in our hospital between november 1991-february 1995. Perinatal @entity1763 was graded as non-severe (first minute Apgar score < or = 6 and/or umbilical artery pH < 7.20, with abnormal fetal heart rate patterns and/or meconium stained amniotic fluid, and the need for immediate neonatal resuscitation) and severe (first minute Apgar score < or = 3 and umbilical artery pH < 7.10). @entity2806 was graded as mild, moderate and severe based on classification of Levene and Sarnat _ Sarnat. The perinatal variables were graded as prenatal (gestationals and obstetrics), neonatal (resuscitation, general data of the newborn, and organic manifestations of @entity1763 ) and postneonatal (neurologic sequelae at follow-up). RESULTS: During the study period there were 3,342 full-term, live births. Perinatal @entity1763 developed in 156 (31 severe and 125 non-severe). Neurologic manifestations were present in 25.6% of asphyxiated newborns: 40 cases of @entity2806 (mild in 30, moderate in 5 and severe in 5). The main differences between asphyxiated newborns with and without @entity2806 were: chronic maternal diseases, pathologic obstetric antecedents, distocic deliveries, neonatal resuscitation, severity of perinatal @entity1763 , sex and weight of newborns, days and origin of admission, @entity99 , extraneurologic manifestations (mainly pulmonary, digestive, haemodynamic and cardiologic) during neonatal period, and neurologic sequelae at follow-up. CONCLUSIONS: The main perinatal differences in relation to postasphyctic @entity75 are important in the knowledgement of their pathogenic mechanism (interrelation between neurologic and extraneurologic manifestations) and their follow-up ( @entity2806 is the most important prognostic factor of neurologic sequelae in the full-term asphyctic newborn).

[Perinatal differences in asphyxic full-term newborns in relation to the presence of XXXX ].

@entity1 :: ('9606', 'Species') :: ['infants'] @entity2806 :: ('MESH:D002545', 'Disease') :: ['hypoxic-ischemic encephalopathy', 'Hypoxic-ischemic encephalopathy'] @entity75 :: ('MESH:D001927', 'Disease') :: ['encephalopathy'] @entity1763 :: ('MESH:D001237', 'Disease') :: ['asphyxia'] @entity99 :: ('MESH:D056486', 'Disease') :: ['birth injury']
@entity2806 :: (MESH:D002545,Disease) :: ['hypoxic-ischemic encephalopathy']
