PURPOSE: Injectable agents are used to increase urethral coaptation for the treatment of @entity1690 . We evaluated the long-term results and complications of transurethral collagen injections in males. MATERIALS AND METHODS: We reviewed the charts of 322 @entity1 (mean age 67.2 years, range 40 to 91) with @entity1690 after therapy for @entity263 (307) or @entity1067 (15) who received transurethral collagen injections. The analysis included types and combinations of treatment for @entity263 or @entity1067 , pre-procedure voiding symptoms, total collagen received, maximal percentage improvement and durability of effect. RESULTS: The mean length of followup was 40.1 (+/-13.2) months. Overall, the mean number of injections was 4.37 (+/-2.09). Mean percent improvement after a series of injections was 44.59 (+/-38.26). Mean pad use before and after injection was statistically different (5.15 vs 2.98, p=0.0001). Mean duration of response was 6.3 (+/-8.14) months. In those who achieved complete continence (17%), the mean duration of response was 11.1 (+/-8.87) months. Within this group the mean number of injections and ml of collagen injected were 3.83 and 29.27, respectively. Five @entity1 (1.5%) complained of a quantitative increase in leakage after their series of collagen injections. CONCLUSIONS: Transurethral collagen injections are a good option for short-term therapy in @entity1 with @entity322 . The mean number of injections to achieve a plateau is 3 to 4, regardless of initial severity of @entity322 . Those in the radical prostatectomy only treatment group are statistically more likely to achieve continence than all other treatment groups.

Transurethral collagen injections for male XXXX : the University of Texas-Houston experience.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity1690 :: ('MESH:D046628', 'Disease') :: ['intrinsic sphincter deficiency'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer', 'prostate carcinoma'] @entity322 :: ('MESH:D014549', 'Disease') :: ['post-prostatectomy incontinence', 'incontinence'] @entity1067 :: ('MESH:D011470', 'Disease') :: ['benign prostatic hyperplasia']
@entity1690 :: (MESH:D046628,Disease) :: ['intrinsic sphincter deficiency']
