BACKGROUND: The incidence of @entity14 ( @entity14 ) shows a wide geographic variation and India along with other Asian and African countries has a low incidence. Most @entity1 present with advanced disease and no uniform treatment guidelines are followed at present. @entity1 AND METHODS: An audit of 91 @entity1 treated as per IRCH protocol between June 1994 and @entity1178 2000 in a single surgical unit was performed. RESULTS: The mean age of @entity1 was 45.3 years (18-90 years) and there was a predominance of @entity5 @entity1 (Rectal vs Colon = 76% vs 24%). Majority of the @entity5 were @entity5 (67%) and abdominoperineal resection was the commonest surgical procedure performed(40). The inoperability rate was 24% and sphincter salvage rate was 13%. Seventy nine percent of @entity1 had @entity420 and 90% of @entity14 @entity1 belonged to Astler-Collers stage B2 and C. A total of 37 @entity1 also received adjuvant radiotherapy and only 39 out of 60 @entity1 planned for adjuvant chemotherapy could complete the treatment. The operative mortality was 2.2% and morbidity was 18%. A total of 13 (14%) @entity1 had @entity66 (local 5, regional 3, distant 5). CONCLUSIONS: A significant number of @entity14 @entity1 in India present with advanced stage of disease and probably due to referral bias majority had @entity5 . By advocating multimodality protocols a good locoregional and systemic control can be achieved despite the advanced stage of presentation.

XXXX --experience at a regional @entity5 centre in India.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity66 :: ('MESH:D004194', 'Disease') :: ['relapse of disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['low rectal cancers', 'rectal cancers', 'rectal cancer'] @entity1178 :: ('3725', 'Gene') :: ['Jun'] @entity14 :: ('MESH:D015179', 'Disease') :: ['CRC', 'colorectal cancer'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma']
@entity14 :: (MESH:D015179,Disease) :: ['Colorectal cancers']
