PURPOSE: This study aimed to investigate the relationship between the number of oocytes retrieved and clinical outcomes in young @entity1 with normal ovarian reserve who were undergoing their first in vitro fertilization and embryo transfer (IVF-ET) cycle. The transfer strategy based on yielded oocytes was also discussed in this article. METHODS: A total of 1567 @entity1 who underwent first long protocol of IVF treatment in our reproductive medical center between January 2010 and June 2014 were categorized into five groups based on the retrieved oocyte number, namely, 4   6, 7   9, 10   12, 13   15, and >= 16. Baseline parameters were similar among the groups. Primary outcome was defined as the cumulative live birth rate (CLBR), and secondary outcomes included the rate of @entity1 with high risks for @entity43 ( @entity43 ). RESULTS: It was found that the CLBR increased with the number of oocytes, as well as the rate for high risks of @entity43 . In fresh cycles, 10   12 oocyte group demonstrated the highest implantation rate (53.32  %), clinical pregnancy rate (CPR) (73.13  %), and live birth rate (LBR) (61.14  %), with no significant differences. Moreover, both cumulative CPR (CCPR) and CLBR became significantly higher in the 10   12 oocyte group, compared with 4   6 and 7   9 groups. However, when the retrieved oocytes increased to 13   15 or >= 16, the cumulative results did not have a significant increase. Also, the high risk rate of @entity43 was much lower in the 10   12 group (11.53  %) than that in the 13   15 group (29.97  %) and >= 16 group (77.30  %). Unconditional multivariate logistic regression analysis showed that when >= 10 oocytes were retrieved, the CLBR increased significantly (P   <   0.01). When oocyte number exceeded 16, the CPR of frozen embryo transfer cycle was much higher than that of fresh cycle (P   <   0.05). CONCLUSIONS: For young @entity1 with normal ovarian reserve, retrieving 10   12 oocytes might result in optimized pregnancy outcomes in a fresh cycle with low @entity43 risk and would not compromise cumulative outcomes. When >= 16 oocytes were retrieved, a "freeze-all" embryo strategy might be preferable.

Optimum oocyte retrieved and transfer strategy in young XXXX with normal ovarian reserve undergoing a long treatment protocol: a retrospective cohort study.

@entity1 :: ('9606', 'Species') :: ['patients', 'women'] @entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian hyperstimulation syndrome', 'OHSS']
@entity1 :: (9606,Species) :: ['women']
