OBJECTIVE: The study was performed to evaluate the results of treatment of @entity43 after the introduction of centralised primary surgery in the County of North Jutland, Denmark. METHOD: Prospective study of consecutive cases of @entity43 undergoing primary surgical treatment at the Gynecologic Oncologic Center after the introduction of centralised primary surgery. Results of treatment recorded up to the date of last examination or @entity204 . RESULTS: From 1999 to 2002, 107 @entity1 with primary @entity43 underwent primary surgery at the Gynecologic Oncologic Center, Aalborg. This corresponds to 95.5% of @entity1 with @entity189 in the County of North Jutland. All @entity1 with Stage I to Stage IIIB disease had a complete, macroscopically radical cytoreduction performed. In @entity1 with Stage III and IV invasive @entity5 , the optimal debulking rate was 79.5%, and, in Stage IIIC and IV, the optimal debulking rate was 78.2%. Intra-operative and post-operative complications were generally few. @entity204 , defined as @entity204 within 30 days after surgery, was observed in 4 cases (3.7%). After primary surgery, @entity902 -based chemotherapy was given in most cases. For Stage I to IV @entity3 , the median survival was 46 months. In @entity1 with Stage IIIC and IV disease, the median survival was 32 months. In optimally debulked Stage IIIC and IV disease, the median survival was 41 months. CONCLUSIONS: The results indicate a survival benefit after introduction of centralised primary surgery. Compared to existing national and regional data on @entity43 , the results indicate an increase in median survival for all stages of approximately 15 months. Centralisation of primary surgery to centres with the necessary expertise may be the most significant way to increase @entity43 in Denmark.

The results of treatment of XXXX after centralisation of primary surgery. Results from North Jutland, Denmark.

@entity43 :: ('MESH:D010051', 'Disease') :: ['ovarian carcinoma', 'ovarian cancer', 'survival in ovarian cancer', 'epithelial ovarian cancer'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity189 :: ('MESH:D002277', 'Disease') :: ['invasive carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['invasive cancer'] @entity204 :: ('MESH:D003643', 'Disease') :: ['Post-operative death', 'death'] @entity902 :: ('MESH:D010984', 'Chemical') :: ['platinum']
@entity43 :: (MESH:D010051,Disease) :: ['epithelial ovarian cancer']
