AIM: The aim of the present study is to evaluate diffusion tensor tractography (DTT) as a tool for detecting @entity21 in @entity1 of acute, mild, and moderate @entity131 ( @entity131 ), using two diffusion variables: Fractional anisotropy (FA) and @entity1893 ( @entity1893 ). The correlation of these indices with the severity of @entity6413 was also assessed. MATERIALS AND METHODS: Nineteen @entity1 with acute, mild, or moderate @entity131 and twelve age- and sex-matched healthy controls were recruited. Following Magnetic Resonance Imaging (MRI) on a 3.0-T scanner, DTT was performed using the 'fiber assignment by continuous tracking' (FACT) algorithm for fiber reconstruction. Appropriate statistical tools were used to see the difference in FA and @entity1893 values between the control and @entity1 groups. In the latter group, the severity of @entity6413 was assessed six months following trauma, using the Rivermead Postconcussion Symptoms Questionnaire (RPSQ). RESULTS: The @entity1 displayed significant reduction in FA compared to the controls (P < 0.05) in several tracts, notably the corpus callosum, fornix, bilateral uncinate fasciculus, and bilateral superior thalamic radiations. Changes in @entity1893 were statistically significant in the left uncinate, @entity9479 . A strong correlation between these indices and the RPSQ scores was observed in several white matter tracts. CONCLUSION: Diffusion tensor imaging (DTI)-based quantitative analysis in acute, mild, and moderate @entity131 can identify @entity21 , over and above that visualized on conventional MRI scans. Furthermore, the significant correlation observed between FA and @entity1893 indices and the severity of @entity6413 could make it a useful predictor of the long-term outcome.

XXXX and the post-concussion syndrome: A diffusion tensor tractography study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity131 :: ('MESH:D001930', 'Disease') :: ['TBI', 'traumatic brain injury'] @entity9479 :: ('MESH:D013786', 'Disease') :: ['inferior longitudinal fasciculus, and left posterior thalamic radiation'] @entity1893 :: ('MESH:D008228', 'Disease') :: ['MD', 'mean diffusivity'] @entity21 :: ('MESH:D001480', 'Disease') :: ['axonal injury neuropathology', 'diffuse axonal injury'] @entity6413 :: ('MESH:D038223', 'Disease') :: ['post-concussive symptoms']
@entity131 :: (MESH:D001930,Disease) :: ['Traumatic brain injury']
