Prophylactic laparoscopic cholecystectomy should be performed in solid organ transplant @entity1 with asymptomatic @entity2963 . Modeled, decision analytic techniques were used to evaluate the different management strategies for asymptomatic @entity2963 in @entity8 . The clinical outcomes of expectant management, pretransplantation prophylactic cholecystectomy, and posttransplantation prophylactic cholecystectomy were analyzed for each population. The probabilities and outcomes were derived form a pooled analysis of published studies. One- and two-way sensitivity and cost analyses were performed. Prophylactic posttransplantation cholecystectomy is favored for cardiac transplant recipients with asymptomatic @entity2963 , resulting in 5:1000 @entity204 versus 80:1000 for pretransplantation cholecystectomy and 44:1000 for expectant management. In distinction, expectant management for asymptomatic @entity2963 is favored in pancreas/renal transplant @entity1 , resulting in 2:1000 @entity204 compared with 5:1000 for prophylactic cholecystectomy. After heart transplantation, a strategy of routine, prophylactic cholecystectomy is anticipated to result in a cost savings of  17,779 per quality-adjusted life-year. Prophylactic posttransplantation cholecystectomy is the preferred management strategy for cardiac transplant @entity1 with incidental @entity5990 , resulting in decreased mortality and significant cost savings per quality-adjusted life-year. Expectant management is the preferred strategy for @entity8 transplant recipients with asymptomatic @entity2963 .

Prophylactic cholecystectomy in transplant XXXX : a decision analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['cardiac and pancreas/renal transplant recipients', 'pancreas and/or kidney'] @entity5990 :: ('MESH:D042882', 'Disease') :: ['gallstones'] @entity2963 :: ('MESH:D002769', 'Disease') :: ['cholelithiasis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths']
@entity1 :: (9606,Species) :: ['patients']
