OBJECTIVE: To analyze the therapeutic results of intervention and the factors affecting the outcome of @entity1 with @entity699 ( @entity699 ) cared for at the All Indian Institute of Medical Science (AIIMS), New Delhi. DESIGN: @entity1 with @entity699 treated at a teritiary care centre from January 2000 to December 2009 were prospectively studied. RESULTS: Ninety-seven @entity1 received treatment for @entity699 during this period. Mean duration of follow-up was 3.4    2.2 (mean    SD) years. Eighty-one @entity1 (83.5%) underwent @entity1104 ( @entity1104 ) as the primary treatment modality. Fifty-four @entity1 (66.7%) went into remission after initial @entity1104 ; ten (18.5%) of them relapsed after a mean follow-up period of 2.9    2.1 (mean    SD) years. Histopathologic examination of resected tissue showed @entity21422 in 48 of the 54 (88.9%) who went into remission and 17 of the 27 (63.0%) who did not go into remission after the initial @entity1104 . Sixteen @entity1 with severe @entity699 underwent bilateral adrenalectomy (BA) as a life-saving measure which was followed by pituitary surgery 6 to 12 months later. Five @entity1 including one with a large macroadenoma required three or more procedures to achieve eucortisolism. CONCLUSION: Fifty-four out of 81 (66.7%) of our @entity1 with @entity699 had remission following initial @entity1104 , ten of whom relapsed later on. Sixteen @entity1 unerwent BA as a life-saving procedure. Factors affecting outcome were, age, gender, low dose @entity619 suppression test @entity701 value and histologic confirmation of @entity21422 .

XXXX : results of treatment and factors affecting outcome.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity21422 :: ('MESH:D049913', 'Disease') :: ['corticotroph adenoma'] @entity699 :: ('MESH:D003480', 'Disease') :: ['CD', "Cushing's disease", 'hypercortisolism'] @entity619 :: ('MESH:D003907', 'Chemical') :: ['dexamethasone'] @entity701 :: ('MESH:D006854', 'Chemical') :: ['cortisol'] @entity1104 :: ('MESH:D000267', 'Disease') :: ['transsphenoidal surgery', 'TSS']
@entity699 :: (MESH:D003480,Disease) :: ['Cushing's disease']
