OBJECTIVE: At presentation of @entity263 , @entity1 with proven lymph node @entity3 (N1) are comparatively rare. It is difficult to give prognostic information based on the present literature. The aim of this study was to evaluate the impact of known risk factors in @entity1 with pelvic node involvement and without distant @entity3 . METHODS: From the population-based, prospective @entity263 @entity5 registry of the South-East Region in Sweden, we collected data on all 181 @entity1 with N1, M0 @entity263 diagnosed from January 1987 to October 2000 with a follow-up to December 2001. Mean follow-up was 62 months. Pre-operative risk factors as age, T-category, serum PSA, @entity5 grade and also primary treatment given was correlated to the outcome. RESULTS: Median age at diagnosis was 65 years. Cancer-specific survival was highly variable with 5-year survival of 72%, a median of 8 years and the projected 13-year figure was 31%. T-category, age, PSA or treatment did not affect the outcome while poorly differentiated @entity5 had a tendency towards lower cancer-specific survival (p=0.0523) when compared to well and moderately differentiated @entity5 . CONCLUSIONS: This population-based cohort of @entity263 @entity1 with pelvic node involvement treated principally with non-curative intent had a median cancer-specific survival of 8 years. Preoperatively known risk factors seem to have but a modest impact on the prognosis for @entity1 in this stage of the disease.

Prognostic factors and survival in node-positive (N1) XXXX -a prospective study based on data from a Swedish population-based cohort.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumours', 'tumour'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity263 :: (MESH:D011471,Disease) :: ['prostate cancer']
