UNASSIGNED: @entity944 ( @entity944 ) is caused by the fungal pathogen, Fusarium virguliforme, and is a major threat to @entity1460 production in North America. There are two major components of this disease: (i) root @entity39 and (ii) @entity944 . Root symptoms consist of root @entity39 with vascular discoloration. Foliar @entity944 is characterized by interveinal @entity24194 and leaf @entity39 , and in severe cases by flower and pod abscission. A major toxin involved in initiating @entity944 has been identified. Nothing is known about how root @entity39 develops. In order to unravel the mechanisms used by the pathogen to cause root @entity39 , the transcriptome of the pathogen in infected @entity1460 root tissues of a susceptible cultivar, 'Essex', was investigated. The transcriptomes of the germinating conidia and mycelia were also examined. Of the 14,845 predicted F. virguliforme genes, we observed that 12,017 (81%) were expressed in germinating conidia and 12,208 (82%) in mycelia and 10,626 (72%) in infected @entity1460 roots. Of the 10,626 genes induced in infected roots, 224 were transcribed only following infection. Expression of several infection-induced genes encoding enzymes with oxidation-reduction properties suggests that degradation of antimicrobial compounds such as the phytoalexin, glyceollin, could be important in early stages of the root tissue infection. Enzymes with hydrolytic and catalytic activities could play an important role in establishing the necrotrophic phase. The expression of a large number of genes encoding enzymes with catalytic and hydrolytic activities during the late infection stages suggests that cell wall degradation could be involved in root @entity39 and the establishment of the necrotrophic phase in this pathogen.

Investigation of the Fusarium virguliforme Transcriptomes Induced during Infection of XXXX Roots Suggests that Enzymes with Hydrolytic Activities Could Play a Major Role in Root Necrosis.

@entity24194 :: ('MESH:D000747', 'Disease') :: ['chlorosis'] @entity1460 :: ('3847', 'Species') :: ['soybean'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity944 :: ('MESH:D003645', 'Disease') :: ['Sudden death syndrome', 'SDS', 'foliar SDS']
@entity1460 :: (3847,Species) :: ['Soybean']
