BACKGROUND: Interactions among several environmental, behavioral, social, and biological variables contribute to the epidemiology of @entity166 ( @entity166 ) and have an impact on the healthcare system and hospitalizations. We evaluated trends in ID hospitalizations at our Department for @entity166 in the last two decades to aid decision-makers in defining appropriate healthcare strategies. METHODS: The discharge diagnoses of all @entity1 admitted to the ID Department of L Sacco University Hospital between 1995 and 2011 were classified by the International Classification of Diseases (ICD-9) grouped in Major Diagnostic Categories (MDC). Linear regression was used to determine the trends in hospitalizations for each MDC. Estimates of the average annual change were based on the slope of the regression line. RESULTS: A sharp decline in @entity645 / @entity791 cases (-22.5 +/-6.0 cases per calendar year), and an increase in admissions for respiratory, @entity65 were recorded. The mean age of the @entity1 increased by 1.2  years (+/-0.049) for each calendar year of observation (linear trend, p   <   0.0001), increasing from 37.02 +/-11.91  years in 1995 to 56.02 +/-19.62  years in 2011 (p   <   0.0001). The mean number of comorbidities per @entity1 increased significantly over time (Mann-Whitney U test, p   =   0.0153). From 1998/1999 to 2010/2011 the hospital length of stay (LOS) increased for cardiovascular, digestive system, musculoskeletal, and skin/subcutaneous infections, and infectious and @entity4801 (p   <   0.01). The rate of hospital stay over threshold (HSOT) increased in the last 5  years by 1.12% for every 10-year age group. CONCLUSIONS: Older age, a higher number of comorbidities, a longer hospital LOS for certain conditions, and a higher rate of HSOT characterize the @entity1 admitted to this ID department in recent years. Despite progress in treatment and management, @entity166 continue to be a major threat to @entity1 health. The current challenge for ID departments is the treatment of complex cases, often associated with @entity102 in elderly @entity1 . Continuous monitoring at a local and national level will allow early identification of changes in the epidemiological patterns of @entity166 and provide information for healthcare system planning.

Trends in hospital admissions at a Department for XXXX in Italy from 1995 to 2011 and implications for health policies.

@entity1 :: ('9606', 'Species') :: ['human', 'patients', 'patient'] @entity645 :: ('57667', 'Species') :: ['HIV'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic diseases'] @entity4801 :: ('MESH:D010272', 'Disease') :: ['parasitic diseases'] @entity791 :: ('MESH:D000163', 'Disease') :: ['AIDS'] @entity166 :: ('MESH:D003141', 'Disease') :: ['infectious diseases', 'Infectious Diseases', 'IDs'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular, renal and musculoskeletal infections']
@entity166 :: (MESH:D003141,Disease) :: ['Infectious Diseases']
