INTRODUCTION: In clinical practice, endoscopic findings are often used for assessing disease activity in @entity29 ( @entity29 ). In recent years, blood and stool markers are being increasingly used for this purpose. Among them, the fecal calprotectin (FC) level is probably the most favored. Data on the reliability of FC are lacking from countries like India, where gut infections are common. OBJECTIVE: The aims of this study were to compare the FC level with the erythrocyte sedimentation rate (ESR) and the @entity1851 ( @entity1851 ) as non-invasive markers of @entity29 and, in @entity1 with @entity31 ( @entity31 ), and to study its correlation with disease extent, clinical activity, and endoscopic severity. METHODS: Records of @entity1 with @entity29 who had tests for FC, ESR and @entity1851 and colonoscopy done within a 2-week period, between 2012 and 2014, were retrieved. Sixty-three @entity1 ( @entity31 32, @entity30 [ @entity30 ] 31) were included for analysis. ESR, @entity1851 and FC were compared to endoscopy to assess @entity32 . RESULTS: @entity1 with @entity31 had higher levels of FC than those with @entity30 (median FC 800  mcg/g vs. 619  mcg/g, respectively; p   =   0.04). FC levels correlated with @entity1851 (r   =   0.4, p   <   0.001) but not with ESR (r   =   0.21, p   =   0.09). In @entity1 with @entity31 with endoscopic evidence of @entity32 , more (86.9  %) had FC >200  mcg/g (cut-off for disease activity in our laboratory) than had ESR >20  mm in the first hour (60.6  %) or positive @entity1851 (65.6  %) (<0.01); FC levels increased with increasing endoscopic Mayo score (p   =   0.001) and Truelove-Witt's clinical severity score (p   =   0.006), but did not correlate with disease extent (p   =   0.7). The best FC cut-off level to identify 'active @entity31 ' (Mayo grade 2 or more) was 800  mcg/g. CONCLUSION: Fecal  calprotectin level correlates with @entity1851 but not with ESR. In @entity1 with @entity31 with @entity32 , FC >200  mcg/g is more often positive than raised ESR or @entity1851 ; it also correlates with clinical and endoscopic activity but not with disease extent. FC level >800  mcg/g can be used to differentiate active from inactive @entity31 .

Fecal  calprotectin and its correlation with inflammatory markers and endoscopy in XXXX from India with @entity29 .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity31 :: ('MESH:D003093', 'Disease') :: ['ulcerative colitis', 'UC'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease', 'IBD'] @entity30 :: ('MESH:D003424', 'Disease') :: ['CD', 'ileocolonic CD', "Crohn's disease"] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein', 'CRP']
@entity1 :: (9606,Species) :: ['patients']
