BACKGROUND: Dietary induction of @entity4059 ( @entity4059 ) can reduce @entity294 in @entity1 with @entity29 . @entity1 with @entity5 may suffer from @entity294 with a prominent secretory component. We studied if @entity4059 -therapy could affect this type of @entity294 . METHODS: Six @entity1 with the midgut @entity4303 and two with metastasizing @entity259 ( @entity259 ) participated. Effects of intake of @entity4059 , in the form of @entity4059 -rich egg powder ( @entity4059 -egg), and induction of endogenous @entity4059 -activity by intake of specially processed cereals (SPCs) were studied. In an initial open part of the study all @entity1 received @entity4059 -egg for 4 weeks, followed by a double-blind crossover period with SPC and control cereals (CCs) for 6 weeks each. Daily number of bowel movements at the end of each treatment period was registered. RESULTS: Treatment with @entity4059 -egg resulted in a @entity717 in seven @entity1 (P<0.01). Registrations of bowel movements from both SPC and CC diet periods were obtained from five @entity1 . The daily number of bowel movements was lower during the SPC-period compared to the period with CC (P<0.05). All @entity1 had low levels of @entity4059 -activity in serum at baseline. During treatment with @entity4059 -egg, the mean level increased slightly. @entity4059 -activity was higher (P<0.05) after SPC compared to the CC diet. CONCLUSIONS: In a group of @entity1 with endocrine @entity294 , @entity4059 -activity could be induced, and @entity4059 -therapy reduced the number of bowel movements.

Antisecretory factor counteracts secretory XXXX of endocrine origin.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity4059 :: ('MESH:D007020', 'Disease') :: ['AF', 'antisecretory factor'] @entity5 :: ('MESH:D009369', 'Disease') :: ['neuroendocrine tumours'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhoea'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease'] @entity4303 :: ('MESH:D002276', 'Disease') :: ['carcinoid syndrome'] @entity717 :: ('MESH:D009069', 'Disease') :: ['decrease of bowel movements'] @entity259 :: ('MESH:D013964', 'Disease') :: ['medullary thyroid carcinoma', 'MTC']
@entity294 :: (MESH:D003967,Disease) :: ['diarrhoea']
