BACKGROUND AND OBJECTIVE: @entity729 ( @entity729 ) is indicated by @entity460 deposits in the coronary artery wall. Calcification is a component of @entity731 and @entity453 . Currently, there are no data on calcification in Saudi @entity1 at high risk of @entity453 . The aim of this study was to investigate the prevalence and percentiles of @entity729 score in high-risk asymptotic @entity1 in Saudi Arabia with comparison of age-specific @entity729 percentiles derived from large population-based published study in the United States. DESIGN AND SETTING: Retrospective analysis of @entity729 scores (CACS) at a single tertiary care center. METHODS: Between January 2011 and April 2015, @entity1 referred for @entity729 screening because of the presence of one or more CAD risk factors were enrolled in the study. CT scans were interpreted by an experienced radiographic technologist, and confirmed by a radiologist. RESULTS: The study sample consisted of 918 @entity1 , mean (SD) age of 55 (11) years. All @entity1 were asymp.tomatic and referred by their primary care physician or cardiologist for @entity729 screening because presence of one or more CAD risks factors. CAD risk factors included @entity6 , @entity101 , @entity1007 , family history of CAD, and @entity28 . Baseline CAD risk factors were remarkably higher than in the US comparator group. CACS for 25th, 50th, 75th, and 90th percentiles were calculated. The 75th and 90th CACS percentiles in Saudi @entity1 were significantly higher than the US percentiles. Age and @entity6 are the most independent predictor of severity of @entity729 . LIMITATIONS: A potential bias due to sample collection because data was from a single tertiary care center, the study was retrospective and the sample size was small. CONCLUSION: There are significantly higher CACS percentiles in Saudi @entity1 compared with international data. Application of available published percentiles to a local population is not applicable and underestimates the severity of subclinical @entity731 . A large local population-based study is warranted to establish local CACS percentiles for a better understanding CAD screening, diagnosis, and treatment.

Coronary artery @entity460 score in high-risk asymptomatic XXXX in Saudi Arabia.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity1007 :: ('MESH:D006937', 'Disease') :: ['hypercholesterolemia'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obesity'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity729 :: ('MESH:D061205', 'Disease') :: ['Coronary artery calcification', 'CAC'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis']
@entity1 :: (9606,Species) :: ['women']
