STUDY OBJECTIVES: To determine the ability of quantitative CT, with special reference to area of @entity2415 , to predict early postoperative oxygenation capacity and outcome after lung lobectomy for @entity5 . METHODS: Sixty-two consecutive @entity1 scheduled to undergo lung lobectomy for @entity5 were enrolled in this study. The area of @entity2415 (< - 910 Hounsfield units) was measured on a three-dimensional CT lung model. Arterial @entity26 saturation (Sao(2)) was calculated from Pao(2) measured 1 day before and 1 day after surgery with @entity1 at rest breathing room air. A @entity1 was considered to have recovered at the completion of a standardized management regimen. RESULTS: Postoperative Sao(2) (postSao(2)) was predicted by the baseline value and the area of @entity2415 with the use of a regression equation. Ten of the 62 @entity1 (16%) had @entity260 (CPCs). The median time to postoperative recovery was 3 days (range, 1 to 17 days). Predicted postSao(2) and predicted postoperative FEV(1) were shown to be significant independent predictors of postoperative CPCs as well as postoperative recovery time. CONCLUSION: Determining the area of @entity2415 by quantitative CT is useful in predicting early postoperative oxygenation capacity. Predicted oxygenation capacity and predicted ventilatory capacity independently affect perioperative outcomes. Therefore, using quantitative CT in combination with spirometry may improve risk prediction in @entity1 undergoing lung lobectomy for @entity5 . However, the role of quantitative CT in grading nonemphysematous @entity358 , such as @entity401 , must be investigated.

Role of quantitative CT in predicting hypoxemia and complications after lung lobectomy for @entity5 , with special reference to area of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity260 :: ('MESH:D011183', 'Disease') :: ['postoperative cardiopulmonary complications'] @entity2415 :: ('MESH:D004646', 'Disease') :: ['emphysema'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung diseases'] @entity401 :: ('MESH:D017563', 'Disease') :: ['interstitial lung diseases']
@entity2415 :: (MESH:D004646,Disease) :: ['emphysema']
