@entity4023 injection into the glenohumeral joint is a treatment option in the management of @entity2585 of the shoulder. We hypothesized that a systematic review would demonstrate that intra-articular @entity4023 injections would result in significant improvements in passive range-of-motion, shoulder and general clinical outcome measures, and @entity158 scales at short- and mid-term follow-up. Multiple medical databases were searched for levels I-IV evidence with a priori defined specific inclusion and exclusion study criteria. Clinical outcome measures used included Constant score, VAS @entity158 scores, Cho functional scores, JOA scores, and range-of-motion measurements. Seven studies were included (four Level I and three Level IV; 292 subjects, 297 shoulders). Mean subject age was 59.1 years and mean pre-treatment duration of symptoms was 7.3 months. 140 subjects underwent one or multiple hyaluronate injections (120 glenohumeral joint; 20 subacromial bursa). Clinical follow-up was mean 9.0 weeks. @entity4023 injection into the glenohumeral joint has significantly improved shoulder range-of-motion, constant scores, and @entity158 at short-term follow-up following treatment of @entity2585 . Isolated intra-articular hyaluronate injection has significantly better constant scores than control. Isolated intra-articular hyaluronate injection has equivalent clinical outcomes and range-of-motion compared to intra-articular corticosteroid injection. Intra-articular @entity17540 injection was safe, with no reported complications within the studies in this review. @entity4023 injection into the glenohumeral joint is a safe, effective treatment in the management of @entity2585 of the shoulder. Short-term evidence indicates that clinical outcomes are better than control and equivalent to intra-articular corticosteroid injection.

Treatment of XXXX with intra-articular hyaluronate: A systematic review.

@entity17540 :: ('CHEBI:16336', 'Chemical') :: ['hyaluronate'] @entity2585 :: ('MESH:D002062', 'Disease') :: ['adhesive capsulitis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity4023 :: ('MESH:D006820', 'Chemical') :: ['sodium hyaluronate', 'Sodium hyaluronate']
@entity2585 :: (MESH:D002062,Disease) :: ['adhesive capsulitis']
