PURPOSE: @entity6795 ( @entity31304 ) are abnormalities of the cerebral cortex that arise from abnormal formation of the cortical plate, and have become increasingly identified as an important etiology for @entity302 . Little is known about the spectrum, distribution and clinical features of @entity31304 , especially in resource-limited regions. This study investigates the distribution of @entity31304 and compares the clinical features and long-term prognosis between the two forms of @entity31304 : Simple and Multiple. METHOD: One hundred and fifty @entity302 @entity1 (138 adults, 12 pediatric @entity1 ) with radiologically diagnosed @entity31304 were identified at a tertiary @entity302 center in western China. @entity1 were divided into three subtypes according to the Barkovich classification. They were further divided into either Simple or @entity2826 forms based on whether they had a single type of @entity31304 or other co-existing @entity75 . RESULTS: The most common type of @entity2826 is focal @entity6795 . We found perinatal insults more common in group III @entity1 . @entity2826 was identified in 36 of 150 @entity1 , and was associated with higher rates of delayed milestones (p=0.005), @entity73 (p=0.023) and @entity51 (p=0.002) compared to Simple @entity2826 . Extra-temporal @entity302 was more commonly seen among individuals with @entity2826 (p=0.017). @entity1 with @entity2826 were younger at time of @entity410 onset (p=0.003) and at assessment (p=0.002), had a lower @entity410 -free rate (p=0.033) and had worse outcomes overall. @entity1 with @entity3664 were more commonly associated with other abnormalities. CONCLUSION: @entity31304 are a critical cause of @entity302 and pose a big challenge for resource-limited countries. Imaging techniques are crucial in diagnosing and classifying @entity85 . @entity600 lead to more severe clinical features and worse prognosis. Identifying and classifying @entity31304 can help physicians to better estimate @entity1 prognosis and seek the best, individualized therapeutic options.

@entity6795 and XXXX : A cohort of 150 @entity1 in western China.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'Participants'] @entity2826 :: ('MESH:D012514', 'Disease') :: ['MCD', 'Multiple MCD'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure'] @entity31304 :: ('MESH:C537834', 'Disease') :: ['MCDs'] @entity75 :: ('MESH:D001927', 'Disease') :: ['developmental brain abnormalities'] @entity73 :: ('MESH:D003072', 'Disease') :: ['cognitive impairment'] @entity3664 :: ('MESH:C548481', 'Disease') :: ['heterotopias'] @entity600 :: ('MESH:D000014', 'Disease') :: ['Multiple malformations'] @entity6795 :: ('MESH:D054220', 'Disease') :: ['cortical dysplasia', 'Malformations of cortical development'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological deficits'] @entity302 :: ('MESH:D004827', 'Disease') :: ['refractory epilepsy', 'epilepsy'] @entity85 :: ('MESH:D009140', 'Disease') :: ['cortical deformities']
@entity302 :: (MESH:D004827,Disease) :: ['epilepsy']
