BACKGROUND: Over the past decades, survival of @entity1 with @entity978 ( @entity978 ) has increased but remains curtailed by cardiovascular mortality (CVM). @entity978 survivors at greatest risk for @entity65 have not been clearly identified. We sought to report trends of CVM identify @entity978 survivors at highest risk. METHODS: The Surveillance, Epidemiology, and End Results (SEER) database was queried for all adult @entity1 diagnosed with @entity978 (age 20-49 years) between 1990 and 2011. The trend of CVM and disparities are presented. RESULTS: Of 19,781 @entity978 @entity1 , 53% were male and 83% were white; @entity1 had a mean age of 33    8.3 years at diagnosis. Eighteen percent had stage I disease, 45% stage II, 18% stage III, and 15% stage IV. The risk for CVM was higher in blacks (adjusted hazard ratio [HR], 1.97; P  = .002), @entity1 (adjusted HR, 2.2; P  < .001), and @entity1 with older age at diagnosis (adjusted HR, 1.073 per year; P  < .001). CVM has decreased, with 5-year cumulative incidence decreasing from 1.17% in 1990 to 0.18% in 2006, averaging 7% per year (adjusted HR, 0.927; P  < .001). This trend was seen only in @entity1 with @entity66 (P  < .001) but not with advanced disease (P  = NS). CVM as a proportion of all-cause mortality increases sharply at 50 years of age, constituting more than 30% of all causes of @entity204 . CONCLUSION: Despite an overall decrease in CVM in @entity978 survivors over the last decades, older @entity1 , black @entity1 , and @entity1 , especially those who have advanced-stage disease at diagnosis, are at the highest risk of @entity65 . Cardiovascular screening and risk modification should be intensified in @entity978 @entity1 with these characteristics.

Trends and Disparities in Cardiovascular Mortality Among Survivors of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity66 :: ('MESH:D004194', 'Disease') :: ['early disease'] @entity978 :: ('MESH:D006689', 'Disease') :: ['HL', 'Hodgkin lymphoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular death']
@entity978 :: (MESH:D006689,Disease) :: ['Hodgkin Lymphoma']
