OBJECTIVE: To assess the clinical outcomes of surgical treatment for acquired @entity2696 in @entity1 who received radical surgery and/or adjuvant radiation therapy for @entity5 . METHODS: A retrospective chart review of eight @entity1 was performed to assess the demographic information, chief complaints, treatment modality for @entity5 , location, and primary treatment modality for vulvar LC, postoperative changes in symptoms, and/or signs, the development of local recurrence and the outcome of @entity1 . RESULTS: All eight @entity1 were previously diagnosed with @entity5 FIGO clinical stage IA to IIA and received surgery, radiation therapy, or concurrent chemoradiation therapy. Microscopic examination revealed multiple, dilated, D2-40-positive dermal vascular channels containing eosinophilic proteinaceous material, consistent with LC. Most chief complaints showed considerable improvements on assessment at the outpatient clinic after the primary surgery. No @entity1 showed aggravation of symptoms. Two @entity1 developed local recurrences. One @entity1 developed recurrence on the opposite side 13  months after local excision. We performed a second wide local excision. Another @entity1 developed recurrence 47  months after the primary surgery. Since the lesion was very small and localized, we decided to manage it conservatively, but monitor it very closely. The remaining six @entity1 remained free of recurrence. CONCLUSION: It is not easy for gynecologists to have an initial clinical diagnosis of LC, because there are a number of diseases that exhibit similar clinical manifestation to that of vulvar LC. Even if it is diagnosed correctly, local recurrence often occurs. Relevant symptoms associated with LC are not only distressing, but also affect @entity1 ' quality of life. Based on our data, we propose that surgical treatment could provide a more long-lasting answer compared to other treatment modalities, since it is beneficial in terms of clinical outcomes. In the future, a long-term follow-up investigation is required to assess the prognosis and to compare the efficacy and side effects of each modality.

Clinical outcomes of primary surgical treatment for acquired XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2696 :: ('MESH:D008202', 'Disease') :: ['vulvar lymphangioma circumscriptum'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cervical cancer']
@entity2696 :: (MESH:D008202,Disease) :: ['vulvar lymphangioma circumscriptum']
