OBJECTIVE: To examine the effect of exercise on overnight @entity4053 in @entity1 with @entity6 ( @entity6 ). STUDY DESIGN: At 5 clinical sites, 50 subjects with @entity6 (age 11 to 17 years) were studied in a clinical research center on 2 separate days. One day included an afternoon exercise session on a treadmill. On both days, frequently sampled blood @entity413 levels were measured at the DirecNet central laboratory. Insulin doses were similar on both days. RESULTS: During exercise, plasma @entity413 levels fell in almost all subjects; 11 (22%) developed @entity4053 . Mean @entity413 level from 10 pm to 6 am was lower on the exercise day than on the sedentary day (131 vs 154 mg/dL; P=.003). @entity4053 developed overnight more often on the exercise nights than on the sedentary nights (P=.009), occurring on the exercise night only in 13 (26%), on the sedentary night only in 3 (6%), on both nights in 11 (22%), and on neither night in 23 (46%). @entity4053 was unusual on the sedentary night if the pre-bedtime snack @entity413 level was>130 mg/dL. CONCLUSIONS: These findings indicate that overnight @entity4053 after exercise is common in @entity1 with @entity6 and support the importance of modifying @entity6 management after afternoon exercise to reduce the risk of @entity4053 .

Impact of exercise on overnight glycemic control in XXXX with @entity6 .

@entity1 :: ('9606', 'Species') :: ['children'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity6 :: ('MESH:D003920', 'Disease') :: ['type 1 diabetes mellitus', 'T1DM', 'diabetes'] @entity4053 :: ('MESH:D007003', 'Disease') :: ['hypoglycemia', 'Hypoglycemia']
@entity1 :: (9606,Species) :: ['children']
