Rotavirus is the most frequent cause of severe @entity294 in @entity1 aged <5 y. A prospective, multicentre, observational study was conducted in Europe during the 2004-2005 rotavirus season. The study was undertaken in areas of Belgium, France, Germany, Italy, Spain, Sweden, and the UK, to estimate the incidence of community-acquired @entity697 ( @entity697 ) and @entity1902 ( @entity1902 ) in @entity1 under 5 y of age seeking medical care in 3 settings: primary care, emergency department, and hospital. A post-hoc analysis was done to further describe the age distribution of @entity1 with @entity1902 . The study included 2846 @entity1 with @entity697 . Of 2712 @entity1 for whom ELISA results were available, 1102 (40.6%) were rotavirus-positive to the results section well. Overall, 86.1% of @entity1902 cases occurred in @entity1 aged between 3 months and 3 y, whereas 1.8% of cases were observed in @entity1 aged less than 3 months. A total of 3.6% of cases occurred in @entity1 aged more than 4 y. These results suggest that, in Europe, routine vaccination for rotavirus should be offered to all @entity1 in early childhood to be effective during the main at-risk period. This could significantly reduce the substantial burden of this potentially serious childhood disease.

Age distribution of paediatric XXXX cases in Europe: the REVEAL study.

@entity1 :: ('9606', 'Species') :: ['children', 'infants'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhoea'] @entity697 :: ('MESH:D000208', 'Disease') :: ['acute gastroenteritis', 'AGE'] @entity1902 :: ('MESH:D005759', 'Disease') :: ['RVGE', 'rotavirus gastroenteritis']
@entity1902 :: (MESH:D005759,Disease) :: ['rotavirus gastroenteritis']
