BACKGROUND: @entity131 ( @entity131 ) is classified into mild, moderate and severe, based on the Glasgow @entity772 Score (GCS). However, @entity131 @entity1 are often influenced by @entity1068 , which in itself can attenuate the level of consciousness. This study investigated the effect of @entity1068 on the GCS group classification in @entity131 @entity1 . METHODS: The Oslo University Hospital trauma database was searched for all @entity1 admitted with a @entity542 where the blood @entity1068 concentration (BEC) had been measured (n   =   1004). The effect of BEC on GCS groups was analysed using multivariate ordinal logistic regression. RESULTS: This study identified 546, 142 and 316 @entity1 in the mild, moderate and severe groups, respectively. Increasing BEC by 1   g   kg(-1) and pre-hospital intubation had OR   =   1.34 and 16.34 for being in a more severe GCS group, respectively. Increasing head abbreviated injury scale (head-AIS) was significantly associated with being in a more severe GCS group. The modelled probability of detecting a head-AIS of 4 or 5 in a @entity1 with BEC of 2.0   g   kg(-1) was 20%, 38% and 65% in the mild, moderate and severe groups, respectively. CONCLUSIONS: Increasing BEC was associated with increasing odds of being in a more severe GCS group. However, because the modelled probability of significant @entity1545 was high in @entity1 with high levels of BEC, a reduced level of consciousness in intoxicated @entity1 mandates further radiological investigations.

The impact of blood @entity1068 concentration on the classification of XXXX severity in @entity131 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1545 :: ('MESH:D020214', 'Disease') :: ['brain injury'] @entity131 :: ('MESH:D001930', 'Disease') :: ['TBI', 'Traumatic brain injury'] @entity542 :: ('MESH:D006259', 'Disease') :: ['head injury'] @entity772 :: ('MESH:D003128', 'Disease') :: ['Coma'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol']
@entity542 :: (MESH:D006259,Disease) :: ['head injury']
