BACKGROUND: Few studies have examined whether @entity75 encountered in @entity1 undergoing meniscectomy should be surgically treated. The primary aim of the ChAMP (Chondral Lesions And Meniscus Procedures) Trial is to determine whether there is a difference in knee @entity158 between @entity1 undergoing debridement versus observation of @entity75 encountered during arthroscopic meniscectomy. This paper describes the rationale and study design for the ChAMP Trial. METHODS/DESIGN: The ChAMP Trial is a randomized controlled trial of @entity1 aged 30 and older undergoing partial meniscectomy and randomly allocated to debridement (CL-Deb, N=98) or observation (CL-Obs, N=92) of @entity75 identified during surgery and deemed to be significant (Outerbridge Grade II-IV). @entity1 and data collectors were unaware of treatment allocation until completion of the study. @entity1 with surgically insignificant (Outerbridge Grade I) @entity75 or no @entity75 were included as a third non-randomized comparison group (NoCL, N=76). The primary outcome is the difference in knee @entity158 assessed by WOMAC (Western Ontario and McMaster Universities Arthritis Index) between the CL-Deb and CL-Obs groups at 1-year after surgery. Secondary outcomes include 1-year differences in additional measures of knee @entity158 , function, symptoms, activity, and quality of life assessed by the WOMAC, KOOS ( @entity3331 and @entity571 Outcome Score), visual analog @entity158 scale, and physical exam; as well as general health assessed with the SF-36 (Short-form Health Survey). Increased intraoperative costs associated with the addition of chondral debridement will also be assessed. DISCUSSION: This study will add to the scant literature regarding management of @entity75 in @entity1 undergoing meniscectomy and might provide treatment guidance for clinicians and their @entity1 .

Design of a randomized controlled trial to compare debridement to observation of XXXX encountered during partial meniscectomy: The ChAMP (Chondral Lesions And Meniscus Procedures) Trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity571 :: ('MESH:D010003', 'Disease') :: ['Osteoarthritis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['chondral lesions'] @entity3331 :: ('MESH:D007718', 'Disease') :: ['Knee Injury'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain']
@entity75 :: (MESH:D001927,Disease) :: ['chondral lesions']
