PURPOSE: The preservation of meniscal structure and function after segmental meniscal loss is of crucial importance to prevent early development of @entity571 . Implantation of artificial meniscal implants has been reported as a feasible treatment option. The purpose of this study was to assess the clinical and magnetic resonance imaging (MRI) results 4  years after implantation of a @entity2636 scaffold for @entity1347 following partial medial meniscectomy. METHODS: Eighteen @entity1 received arthroscopic implantation of an Actifit(  ) @entity2636 meniscal implant (Orteq Sports Medicine, London, UK) for deficiency of the medial meniscus. @entity1 were followed at 6, 12, 24, and 48  months. Clinical outcome was assessed using established @entity1 -reported outcome scores (KOOS, KSS, UCLA Activity Scale, VAS for @entity158 ). Radiological outcome was quantified by MRI scans after 6, 12, 24, and 48  months evaluating scaffold morphology, tissue integration, and status of the articular cartilage as well as signs of @entity32 . RESULTS: Median @entity1 age was 32.5  years (range 17-49  years) with a median meniscal defect size of 44.5  mm (range 35-62  mm). Continuing improvement of the VAS and KSS Knee and Function Scores could be observed after 48  months compared to baseline, whereas improvement of the activity level according to UCLA continued only up to 24  months and decreased from there on. The KOOS Score showed significant improvement in all dimensions. MRI scans showed reappearance of bone bruises in two @entity1 with scaffold extrusion. No significant changes in the articular cartilage could be perceived. CONCLUSION: Arthroscopic treatment for @entity1 with @entity1347 using a @entity2636 meniscal implant can achieve sustainable midterm results regarding @entity158 reduction and knee function. LEVEL OF EVIDENCE: IV.

Midterm follow-up after implantation of a XXXX meniscal scaffold for segmental medial meniscus loss: maintenance of good clinical and MRI outcome.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity571 :: ('MESH:D010003', 'Disease') :: ['osteoarthritis'] @entity1347 :: ('MESH:C537775', 'Disease') :: ['chronic segmental meniscal loss', 'chronic segmental medial meniscus deficiency'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity2636 :: ('MESH:D011140', 'Chemical') :: ['polyurethane']
@entity2636 :: (MESH:D011140,Chemical) :: ['polyurethane']
