To identify factors influencing outcome and morbidity in @entity1 selected for @entity6789 , we retrospectively reviewed 23 @entity1 with intractable generalized @entity410 who underwent @entity6789 between 1991 and 1994. Three @entity1 had a complete @entity6789 , while 20 had an anterior callosotomy. Three of those @entity1 subsequently had completion of the anterior callosotomy. Overall, 41% of @entity1 were nearly or completely free of the @entity410 types targeted for surgical treatment, while another 45% had @entity410 less than half as frequently. Four @entity1 developed simple partial motor @entity410 after callosotomy. A transient disconnection syndrome was observed in 57% of @entity1 . The best predictor of good outcome was a normal preoperative MRI. @entity1032 @entity1 had poorer outcomes. Outcome was not predicted by extent of callosal section or lateralization on neurological examination, EEG, MRI, and SPECT. Completion of anterior callosotomy resulted in significant reductions in @entity410 frequency. Though most @entity1 do not become @entity410 -free after @entity6789 , worthwhile palliation of an otherwise intractable illness can be achieved. An analysis of prognostic factors should lead to better selection of @entity1 for surgery.

Corpus callosotomy for medically intractable XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures'] @entity6789 :: ('MESH:D061085', 'Disease') :: ['corpus callosotomy'] @entity1032 :: ('MESH:D008607', 'Disease') :: ['Mentally retarded']
@entity410 :: (MESH:D012640,Disease) :: ['seizures']
