OBJECTIVE: To determine the expression of @entity31653 , @entity31652 , @entity2285 , @entity2284 ) in @entity189 and normal laryngeal mucosa. METHODS: Total RNA were extracted from 21 @entity5 tissue samples and the normal mucosa of the corresponding larynx. The expression of HSPs mRNA was examined by Slot blot analysis. RESULTS: 1. @entity4041 and @entity2285 were selectively overexpressed 5 times more in @entity189 than in normal mucosa of larynx. 2. @entity31652 and @entity2284 were constitutively expressed at low level in these two groups. There was no significant difference between the levels of expression of @entity31652 and @entity2284 in @entity189 and normal controls. CONCLUSION: The results that @entity4041 and @entity2285 mRNA were selectively overexpressed in @entity189 suggested that @entity4041 and @entity2285 might play a specific role in the pathogenesis of @entity5 . To clarify the mechanism of HSPs action could help to provide theorical basis for the biological therapy of @entity5 .

[Expression of heat shock proteins in XXXX ].

@entity31653 :: ('3324', 'Gene') :: ['HSPs(HSP90 alpha'] @entity4041 :: ('3320', 'Gene') :: ['HSP90 alpha'] @entity2284 :: ('3315', 'Gene') :: ['HSP27'] @entity2285 :: ('3308', 'Gene') :: ['HSP 70', 'HSP70'] @entity5 :: ('MESH:D009369', 'Disease') :: ['laryngeal cancer'] @entity189 :: ('MESH:D002277', 'Disease') :: ['laryngeal carcinoma'] @entity31652 :: ('3326', 'Gene') :: ['HSP90 beta']
@entity189 :: (MESH:D002277,Disease) :: ['laryngeal carcinoma']
