OBJECTIVES: We examined cause of @entity204 in relation to age, length of follow-up and other baseline characteristics in @entity1 in the 1985-1986 National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty (NHLBI PTCA) Registry. BACKGROUND: The manner in which cardiac versus noncardiac mortality of @entity1 with coronary revascularization varies in relation to @entity1 and study characteristics has not been well documented. METHODS: Cause of @entity204 determined from a review of 5 years of annual follow-up forms and @entity204 certificates was analyzed in 2,127 @entity1 who had coronary angioplasty (mean age 57.6 years) without acute @entity583 . RESULTS: Within 5 years of the initial procedure, there were 205 deaths (9.6%), with 52.7% attributed to cardiac causes. @entity1 with a low baseline ejection fraction, history of @entity101 , previous bypass surgery, previous @entity583 , inoperable or high surgical risk or multivessel disease had significantly higher 5-year cardiac mortality. @entity1 with a history of @entity6 , @entity712 or severe concomitant noncardiac disease had higher rates of both cardiac and noncardiac mortality. As length of follow-up increased, older @entity1 died of noncardiac causes more often than cardiac causes. Age > or = 65 years was a strong independent predictor of 5-year noncardiac mortality (p < 0.001), but not cardiac mortality (p = 0.08). CONCLUSIONS: All-cause mortality rates may be high in elderly revascularized @entity1 , yet cardiac mortality may be less than that expected because of a high risk of @entity204 . Although all-cause mortality is a more reliable end point than cause-specific mortality, both cardiac and all-cause mortality should be considered in coronary intervention studies involving older @entity1 and long-term follow-up.

Cause of XXXX analysis in the NHLBI PTCA Registry: results and considerations for evaluating long-term survival after coronary interventions.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity712 :: ('MESH:D006333', 'Disease') :: ['congestive heart failure'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity204 :: ('MESH:D003643', 'Disease') :: ['noncardiac death', 'death']
@entity204 :: (MESH:D003643,Disease) :: ['death']
