PURPOSE: Giant pediatric @entity5 (GPIT) remains to be a challenging disease with high morbidity and mortality. METHODS: The clinical data of 60 @entity1 under 18  years of age operated on with GPIT (>= 5  cm in diameter) were retrospectively analyzed. RESULTS: Gross total resection was achieved in 46 cases (77%) and subtotal resection was obtained in 14 cases (23%). Ninety percent (47/52) of the cases with obstructive @entity1276 were resolved remarkably and only 10% (5/52) of the @entity1 needed a ventriculoperitoneal shunt after @entity5 resection. Postoperative histopathological type revealed @entity1313 in 51 cases (85%). The most common @entity5 was @entity2946 ; other types include the following: @entity424 , @entity816 , @entity11 , @entity6196 ( @entity6196 ), @entity816 , @entity6010 , @entity3038 , @entity9204 , and @entity5606 ( @entity5606 ). Benign histopathological categories include the following: @entity976 , @entity2846 , and @entity1653 . No @entity204 or serious complications occurred after the operation. However, transient subcutaneous effusion occurred in 14 @entity1 postoperatively, @entity128 including the posterior cranial nerve in two cases and abduction nerve in one case, and mutism and @entity358 were observed in two cases, respectively. The follow-up period ranged from 1 to 72  months, with an average of 32  months. Poor prognosis occurred significantly in the high-grade @entity5 and @entity6196 , @entity5606 , and @entity3038 were implicated in the @entity204 of @entity1 within 1  year. CONCLUSIONS: To the best of our knowledge, the present study is the first description of clinicopathological features and the largest case analysis for GPIT. Optimal outcomes for GPIT were achieved by strict evaluation and perioperative management as well as microsurgical skills.

Clinicopathological features and microsurgical outcomes for giant pediatric XXXX in 60 consecutive cases.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6196 :: ('MESH:D018242', 'Disease') :: ['primitive neuroectoderm tumor', 'PNET'] @entity6010 :: ('MESH:D005729', 'Disease') :: ['gangliocytoma'] @entity3038 :: ('MESH:D018316', 'Disease') :: ['gliosarcoma'] @entity424 :: ('MESH:D004806', 'Disease') :: ['ependymoma'] @entity1276 :: ('MESH:D006849', 'Disease') :: ['hydrocephalus'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['malignant brain tumors'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'neoplasm', 'intracranial tumor', 'malignant tumors'] @entity5606 :: ('MESH:D018335', 'Disease') :: ['AT/RT', 'atypical teratoid rhabdoid tumor'] @entity128 :: ('MESH:D020209', 'Disease') :: ['nerve injury'] @entity11 :: ('MESH:D005910', 'Disease') :: ['mixed glioma'] @entity1653 :: ('MESH:D008579', 'Disease') :: ['meningioma'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary infection'] @entity816 :: ('MESH:D001254', 'Disease') :: ['pilocytic astrocytoma', 'subependymal giant cell astrocytoma'] @entity2846 :: ('MESH:D020288', 'Disease') :: ['choroid plexus papilloma'] @entity976 :: ('MESH:D003397', 'Disease') :: ['craniopharyngioma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity2946 :: ('MESH:D008527', 'Disease') :: ['medulloblastoma'] @entity9204 :: ('MESH:C562943', 'Disease') :: ['choroid plexus carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['intracranial tumor']
