The objective of this study was to determine the epidemiology of @entity5 of the central nervous system (CNS) in pediatric @entity1 from a Brazilian oncology institute. We retrospectively analyzed 741 charts (415 males and 326 females) of @entity1 under 21 years of age who were diagnosed with a @entity1221 . The analysis included @entity1 from 1989 to 2009 and was performed using the World Health Organization criteria. We evaluated the distribution of age, sex, topography, clinical symptoms, symptom intervals, and classification of the @entity5 . @entity1 with clinical/radiologic diagnoses were included. Seven hundred forty-one @entity1 with @entity5 in the CNS were reviewed, and 83% of the @entity1 presented a histologic diagnosis. Males (56%) were more prevalent than females. In @entity1 under the age of 1 year, the supratentorial compartment was the predominant region involved (62.0%). Astrocytoma was the most frequent @entity5 type (37.0%), followed by @entity2946 (13.6%), @entity976 (10.5%), and @entity424 (6.8%). Headaches were the most common symptom, and the symptom intervals varied from 1 to 5010 days. Approximately 4% of the @entity1 had associated @entity74 . Although it was not a population study and selection bias may have occurred, this study supplies important epidemiologic data from an emerging country in which population studies are rare.

XXXX : a single-center experience from 1989 to 2009.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients'] @entity424 :: ('MESH:D004806', 'Disease') :: ['ependymoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumors', 'tumors'] @entity1221 :: ('MESH:D016543', 'Disease') :: ['CNS tumor'] @entity74 :: ('MESH:D030342', 'Disease') :: ['genetic syndromes'] @entity976 :: ('MESH:D003397', 'Disease') :: ['craniopharyngioma'] @entity2946 :: ('MESH:D008527', 'Disease') :: ['medulloblastoma']
@entity1221 :: (MESH:D016543,Disease) :: ['Pediatric central nervous system tumors']
