BACKGROUND: Rapid and safe endotracheal intubation is of paramount importance in general anaesthesia. The aim of this study was to compare the intubating conditions of @entity2900 with @entity2898 and @entity3369 using "Timing principle". The timing principle entails administration of a single bolus dose of nondepolarizing muscle relaxant, followed by an induction drug at the onset of @entity425 . @entity1 #ENTITYSTARTX00026; METHODS: 75 @entity1 were divided into three groups of 25 each. @entity1 allocated to Groups A and B received @entity2898 0.6 mg kg(-1) and @entity3369 0.12 mg kg(-1) respectively. At the onset of @entity425 ( @entity1736 ), anesthesia was induced with @entity1875 2.5 mg kg(-1); intubation was accomplished after 60 seconds of induction agent in both groups. @entity1 in Group C received @entity1875 2.5mg kg(-1) followed by @entity2900 2mg kg(-1) and their tracheas were intubated at 60s.Train of four count was assessed at adductor pollicis muscle using nerve stimulator at intubation and time to loss of @entity215 was observed. in group A and B. Intubating conditions were assessed according to a grading scale and haemodynamic variables were compared at 1,3 and 5 minutes after intubation. RESULTS: Intubating conditions were either excellent(84% in group A,48% in group B and 88% in group C) or good (16% in group A, 48% in group B and 12 %in group C)and only 4% pt had poor intubating conditions in group B. @entity1 were interviewed postoperatively, and all were satisfied with the technique of induction of anesthesia.Rocuronium and @entity3369 are haemodynamically stable drugs as compared to @entity2900 . CONCLUSION: Rocuronium 0.6 mg kg(-1) provides good to excellent intubating conditions at 60 s comparable to @entity2900 after the induction of anesthesia using the timing principle.

Comparison of intubating conditions of @entity2898 and @entity3369 with XXXX using "timing principle".

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity3369 :: ('MESH:D014673', 'Chemical') :: ['vecuronium', 'vecuronium bromide', 'Vecuronium'] @entity215 :: ('MESH:D013771', 'Disease') :: ['TOF'] @entity425 :: ('MESH:D018908', 'Disease') :: ['clinical weakness'] @entity1875 :: ('MESH:D015742', 'Chemical') :: ['propofol'] @entity2898 :: ('MESH:C061870', 'Chemical') :: ['rocuronium', 'rocuronium bromide'] @entity1736 :: ('MESH:D001763', 'Disease') :: ['ptosis'] @entity2900 :: ('MESH:D013390', 'Chemical') :: ['Succinylcholine', 'succinylcholine']
@entity2900 :: (MESH:D013390,Chemical) :: ['succinylcholine']
