OBJECTIVE: To investigate the occurrence, genetic inheritance, and @entity393 conditions of @entity8468 ( @entity8468 ), and to measure the width of external aperture of vestibular aqueduct (VA) of @entity8468 , and to analyze the relationship between the @entity393 and the width of external aperture. METHODS: A retrospective review was conducted by the history, auditory, and vestibular function examinations in 95 @entity1 (190 ears) of @entity8468 . The width of VA was measured by CT scanning criterion of each @entity8468 @entity1 in the past 10 years (from 1992 to 2002). RESULTS: In 95 @entity1 , there were male 65 cases and female 30 cases. The male cases was more than the females by a ratio of 2.2:1. Twelve cases (12.6%) would have familial genetic history. The average of the consult age was 7.6 years (range from 1.2 to 39 years). The most @entity1 were misdiagnosed, the @entity393 originated from mild @entity542 in 21 cases (22.1%), the @entity393 after common cold in 13 cases (13.6%). Nine cases (9.5%) misdiagnosed as @entity2459 , 5 cases (5.3%) as @entity2167 @entity393 of @entity4028 antibiotic. The profound @entity393 was found in 172 ears (92.4%). The average width of external aperture of @entity8468 was 7.5 mm +/- 1.2 mm (mean +/- s, 77 cases, 154 ears). The level of @entity393 did not proportional to the width of VA. The @entity393 could be derived from protein-rich endolymph refluxed into the cochlear and vestibule. CONCLUSION: The @entity8468 is distinct clinical entity characterized by fluctuate and progressive SNHL. The diagnosis depends upon the CT scan and MR image. If the hearing fluctuated and subsequently improved, the @entity1 were kept under conservation treatment. If the significantly decreased of hearing effected school performance, the cochlear implant might be considered.

[Clinical analysis of 95 XXXX with @entity8468 ].

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity2167 :: ('MESH:D006311', 'Disease') :: ['ototoxic'] @entity542 :: ('MESH:D006259', 'Disease') :: ['head trauma'] @entity8468 :: ('OMIM:600791', 'Disease') :: ['LVAS', 'large vestibular aqueduct syndrome'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss', 'hearing deterioration', 'hearing impairment'] @entity4028 :: ('CHEBI:47779', 'Chemical') :: ['Aminoglycoside'] @entity2459 :: ('MESH:D003639', 'Disease') :: ['sudden hearing loss']
@entity1 :: (9606,Species) :: ['patients']
