PURPOSE: To describe the clinical features and response to treatment of @entity1 with @entity712 ( @entity751 ) and to propose a hypothesis for a decompensation mechanism in such @entity1 . METHODS: Fourteen adults with @entity751 who had been symptomatically stable for a mean duration of 25 years developed @entity892 in the absence of @entity16 . After retrospective chart review, they underwent detailed orthoptic testing. Results from this cross-sectional analysis were compared with similar data from 16 control subjects with stable @entity751 . RESULTS: Compared to stable @entity751 @entity1 , decompensated subjects had significantly poorer horizontal fusional amplitudes but greater torsional fusional amplitudes; they were also more likely to have a small vertical strabismus and to have received initial treatment later. Stable subjects, however, also had subnormal horizontal as well as torsional fusional amplitudes. There was no difference between groups with respect to @entity2516 , @entity4457 , type or prior treatment of strabismus, stereoacuity, or angle of deviation. After treatment, all @entity1 regained monofixational alignment, but up to one-third had continued @entity892 . Symptoms recurred in two @entity1 whose treatment was initially successful. CONCLUSIONS: @entity1 with @entity751 lose fusional amplitudes over time. In some cases this results in development of sensory torsion with secondary decompensation and @entity892 . The rate of decompensation averages 7% per year from ages 20 to 70. Treatment for decompensation offers excellent motor results, but sensory symptoms may persist and recurrent symptoms may develop. Monitoring and maintenance of fusional vergence amplitudes should be part of the routine care for @entity1 with @entity751 .

The XXXX (an American Ophthalmological Society thesis).

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity712 :: ('MESH:D006333', 'Disease') :: ['decompensated monofixation syndrome'] @entity2516 :: ('MESH:D012030', 'Disease') :: ['refractive error'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic or orbital disease'] @entity751 :: ('MESH:D013577', 'Disease') :: ['MFS'] @entity892 :: ('MESH:D004172', 'Disease') :: ['diplopia'] @entity4457 :: ('MESH:D000550', 'Disease') :: ['amblyopia']
@entity712 :: (MESH:D006333,Disease) :: ['decompensated monofixation syndrome']
