The authors evaluated the relation between occupational exposure to extremely low frequency (ELF) magnetic fields and mortality from @entity65 . The study was based on 27,790 subjects from the Swedish Twin Registry. Exposure to ELF magnetic fields was assessed by linking occupation reported in 1967 or 1973 to a job exposure matrix. Four levels of exposure were related to cause-specific mortality through 1996, and primary and contributing causes of @entity204 were considered. The authors estimated relative risks by Cox regression, with adjustment for several @entity65 risk indicators. The authors calculated the synergy index to evaluate potential interaction between exposure to ELF magnetic fields (>0.2 microT) and genetic susceptibility to @entity583 ( @entity583 ). @entity943 -related @entity204 , @entity63 @entity299 other than @entity583 , and @entity731 showed no association with ELF magnetic fields. The authors found a low-level increase in @entity583 risk in the highest exposure group (relative risk=1.3, 95% confidence interval: 0.9, 1.9) and suggestions of an exposure-response relation (p=0.02). A synergy index of 2.7 (95% confidence interval: 1.1, 6.6) in monozygotic twins indicated that the risk of @entity583 was strengthened among ELF magnetic field-exposed subjects with genetic susceptibility to the disease. The results for @entity583 corroborate previous findings from the United States. The unusual opportunity to include genetic susceptibility in the present analyses showed that evaluations of effect modification in vulnerable subjects are warranted in ELF magnetic field research.

Occupational exposure to extremely low frequency magnetic fields and mortality from XXXX .

@entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease', 'cardiovascular diseases'] @entity299 :: ('MESH:D006331', 'Disease') :: ['heart disease'] @entity583 :: ('MESH:D009203', 'Disease') :: ['AMI', 'acute myocardial infarction'] @entity943 :: ('MESH:D001145', 'Disease') :: ['Arrhythmia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular disease']
