BACKGROUND AND OBJECTIVES: Aberrant circadian rhythm with persistent nocturnal sympathetic hyperactivity has pointed out malfunctioning autonomic nervous system in @entity239 ( @entity239 ) @entity1 . This is a common pathogenesis shared also by @entity1 with nondipping blood pressure (BP) pattern. Therefore, we aimed to investigate the frequency of nondipping BP pattern in normotensive @entity1 with newly diagnosed @entity239 compared with healthy @entity1 . METHODS: Sixty-seven normotensive @entity1 with new diagnosis of @entity239 and 38 age-matched healthy volunteer @entity1 were recruited into the study. All subjects underwent 24-hour ambulatory BP monitoring on a usual working day. Individuals were defined as "dippers" if their nocturnal BP values decreased by more than 10% compared with daytime values; defined as "nondippers" in case of a decline less than 10%. Serum @entity1011 , fasting blood @entity413 , @entity165 levels, albumin, and thyroid-stimulating hormone levels were assessed. RESULTS: Ambulatory measurements showed significantly higher diastolic BP values in @entity1 with @entity239 for both average of 24-hour recordings. @entity1 with @entity239 had significantly lower systolic (9.1    3.9 vs 11.5    4.9, P = 0.010) and diastolic dipping ratios (12.3    6.1 vs 16.1    6.4, P = 0.004). The number of nondippers in the @entity239 group was significantly higher than that of controls for both systolic (66% vs 34%, P = 0.002) and diastolic BP measurements (42% vs 21%, P=0.031). @entity1 with @entity239 were 3.68 times more likely to be systolic nondipper and 2.69 times more likely to be diastolic nondipper. CONCLUSIONS: We have demonstrated a significant relationship between @entity239 and nondipping BP pattern, and we suggest that nondipping profile, which has been closely associated with @entity65 , may appear as an additional risk factor in @entity1 with @entity239 .

XXXX and nondipper circadian blood pressure variability.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients'] @entity239 :: ('MESH:D005356', 'Disease') :: ['fibromyalgia', 'FM'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular morbidity'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity239 :: (MESH:D005356,Disease) :: ['Fibromyalgia']
