@entity1 who develop @entity1468 are at high-risk for premature @entity65 and @entity204 . The aim of this study was to assess microvascular function and @entity65 in the early postpartum period for @entity1 who did/did not have a pregnancy complicated by @entity1468 . Peripheral microvascular function was assessed in @entity1 in the third trimester of uncomplicated pregnancies, with re-evaluation at 2 and 6 months postpartum. The effect of @entity1468 on postpartum microvascular function was assessed 2 and 6 months after delivery. Never-pregnant, naturally cycling @entity1 served for comparison. Cutaneous microvascular reactivity to @entity934 and @entity1854 , delivered locally by iontophoresis, was measured by laser Doppler flowmetry. 30-year and lifetime risk estimates for @entity65 were established. @entity934 -mediated vasodilation was enhanced by normotensive pregnancy, and declined to nonpregnant levels by 6 months postpartum. @entity934 -mediated vasodilation remained high in pre-eclamptic subjects from 2 to 6 months postpartum compared to normotensive and never-pregnant controls. Pre-eclamptic subjects exhibited elevated 30-year and lifetime risk at 6 months postpartum. This study provides in vivo evidence of microvascular and @entity65 implications of @entity1468 as early as 6 months postpartum, and suggests that the development of @entity1468 may be used to identify @entity1 at risk and eligible for risk screening and intervention.

Increased microvascular vasodilation and XXXX following a pre-eclamptic pregnancy.

@entity1 :: ('9606', 'Species') :: ['women', 'Women'] @entity1854 :: ('MESH:D009599', 'Chemical') :: ['sodium nitroprusside'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['pre-eclampsia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease', 'cardiovascular risk'] @entity934 :: ('MESH:D000109', 'Chemical') :: ['acetylcholine', 'Acetylcholine']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular risk']
