OBJECTIVES: Persistent left ventricular (LV) @entity1184 after surgery is frequent, but its clinical relevance is controversial. We evaluated if residual @entity4346 ( @entity1184 ) is associated with clinical outcomes after aortic valve replacement (AVR) for severe @entity472 ( @entity472 ). METHODS: We analysed clinical and echocardiographic parameters before and after AVR, in a prospective cohort of 132 @entity1 with severe @entity472 . The mean follow-up was 6.0    1.5 years. Clinical endpoints were all-cause @entity204 and combination of as in all-cause @entity204 and non-fatal cardiovascular hospitalization. At AVR, myocardial biopsies for collagen volume fraction (CVF) evaluation were done in 56 random @entity1 . RESULTS: Residual @entity1184 was present in 44% of @entity1 after AVR. @entity1 with residual @entity1184 were older, more frequently @entity1 and had @entity101 ( @entity101 ). Preoperatively, they had higher LV mass indices (LVMI), higher E/e' and left atrial volume indices, as well as lower peak systolic annular velocity. Female gender, @entity101 , LVMI and E/e' were independent predictors of persistent @entity1184 . CVF at the time of surgery was higher in those with residual @entity1184 (20.0    14.6 vs 13.2    11.5%, P = 0.027). The risk of all-cause @entity204 and non-fatal cardiovascular hospitalization was higher in @entity1 with residual @entity1184 [OR 2.89 (95% CI 1.12-7.44); P = 0.035], but there were no differences in all-cause mortality. Residual @entity1184 was associated with a worse outcome in @entity1 but not in @entity1 . CONCLUSIONS: Residual @entity1184 after AVR is common and is associated with worse prognosis, particularly in @entity1 . In addition, @entity101 , higher baseline @entity10389 and worse @entity67 can help to identify @entity1 at risk for incomplete normalization of @entity10389 .

Relevance of residual left ventricular hypertrophy after surgery for isolated XXXX .

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'men'] @entity101 :: ('MESH:D006973', 'Disease') :: ['HT', 'hypertension'] @entity67 :: ('MESH:D018754', 'Disease') :: ['diastolic dysfunction'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['LVH', 'hypertrophy'] @entity10389 :: ('MESH:C536141', 'Disease') :: ['LVM'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['LV hypertrophy'] @entity472 :: ('MESH:D001024', 'Disease') :: ['AS', 'aortic stenosis'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity472 :: (MESH:D001024,Disease) :: ['aortic stenosis']
