BACKGROUND: The associations between @entity358 ( @entity565 , @entity1030 [ @entity1030 ], and @entity378 [ @entity378 ]) and subsequent @entity2 risk have been reported, but few studies have investigated the association with different histologic types of @entity2 . METHODS: @entity1 newly diagnosed with @entity2 from 2004 to 2008 were identified from the National Health Insurance Research Database in Taiwan. Histologic types of @entity2 were further confirmed using the Taiwan Cancer Registry Database. Cox proportional hazards regression was used to calculate the hazard ratio (HR) of @entity565 , @entity1030 , and @entity378 and to estimate the risk of specific types of @entity2 . RESULTS: During the study period, 32,759 cases of @entity2 were identified from 15,219,024 insurants aged 20  years and older. In @entity1 and @entity1 , the adjusted HR estimates of @entity957 were respectively 1.37 (95  % confidence interval [CI], 1.21-1.54) and 2.10 (95  % CI, 1.36-3.23) for @entity378 , 1.52 (95  % CI, 1.42-1.64) and 1.50 (95  % CI, 1.21-1.85) for @entity565 , and 1.66 (95  % CI, 1.56-1.76) and 1.44 (95  % CI, 1.19-1.74) for @entity1030 . Similarly, the adjusted HR estimates of @entity420 were respectively 1.33 (95  % CI, 1.19-1.50) and 1.86 (95  % CI, 1.57-2.19) for @entity378 , 1.13 (95  % CI, 1.05-1.21) and 1.18 (95  % CI, 1.09-1.28) for @entity565 , and 1.50 (95  % CI, 1.42-1.59) and 1.33 (95  % CI, 1.25-1.42) for @entity1030 . The @entity4153 were respectively 1.24 (95  % CI, 1.01-1.52) and 2.23 (95  % CI, 1.17-4.25) for @entity378 , 1.51 (95  % CI, 1.35-1.69) and 1.63 (95  % CI, 1.16-2.27) for @entity565 , and 1.39 (95  % CI, 1.26-1.53) and 1.78 (95  % CI, 1.33-2.39) for @entity1030 . CONCLUSIONS: @entity565 , @entity1030 , and @entity378 were associated with an increased risk of all major subtypes of @entity2 . The risk was the highest among @entity1 with @entity378 .

The effects of XXXX on histologic types of @entity2 in both sexes: a population-based study in Taiwan.

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'Patients'] @entity4153 :: ('MESH:D018288', 'Disease') :: ['HRs of small cell carcinoma'] @entity565 :: ('MESH:D001249', 'Disease') :: ['Asthma', 'asthma'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity2 :: ('MESH:D008175', 'Disease') :: ['lung cancer'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary diseases'] @entity1030 :: ('MESH:D029424', 'Disease') :: ['chronic obstructive pulmonary disease', 'COPD'] @entity378 :: ('MESH:D014376', 'Disease') :: ['TB', 'tuberculosis'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma']
@entity358 :: (MESH:D008171,Disease) :: ['pulmonary diseases']
