UNASSIGNED: @entity302 activity was analyzed during pregnancy, the postpartum period and after weaning to establish alterations of @entity410 throughout the reproductive cycle. Wistar Albino Glaxo Rijswijk (WAG/Rij) @entity35 were used in the study as a model of @entity2048 and because their @entity410 do not interfere with rearing offspring. The number of @entity11228 ( @entity11228 ) was gradually elevated from the 19(th) pregnancy day to delivery. Meanwhile, the characteristics of individual @entity11228 did not change suggesting that SWD generation remained the same. In the postpartum and postweaning periods, the number of @entity11228 was not increased in the absence of pups. However, returning the pups to mothers resulted in a markedly elevated number of @entity11228 for 1 h. If pups were taken away after 30 min, the number of @entity11228 dropped immediately suggesting that the presence of pups increased the SWD number. The time mothers spent with the litter and in @entity1513 suckling posture were in correlation with their SWD number further suggesting the importance of interaction with pups in SWD induction. Suckling elevates prolactin levels but surprisingly, its intracerebroventricular injection markedly reduced SWD number in suckled WAG/Rij mothers suggesting that the SWD-inducing effect of suckling is not mediated by prolactin. Rather, the elevated prolactin level may provide some protection against pro- @entity302 effects of suckling. In conclusion, we first identified periods within the reproductive cycle with increased @entity302 activity, implying that more attention should be devoted to @entity302 activity changes in mothers.

@entity302 activity in Wistar Albino Glaxo Rijswijk XXXX mothers.

@entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity1513 :: ('MESH:D007738', 'Disease') :: ['kyphosis'] @entity11228 :: ('MESH:C535500', 'Disease') :: ['SWDs', 'spike-wave discharges'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epileptic', 'Absence epileptic', 'absence epileptic'] @entity2048 :: ('MESH:D004832', 'Disease') :: ['absence epilepsy'] @entity35 :: ('10116', 'Species') :: ['rats']
@entity35 :: (10116,Species) :: ['rat']
