BACKGROUND: The altered hemodynamics, and therefore the arterial @entity551 is the most prevalent adverse effect after @entity510 . The objective of the study was to determine the exact role of local anesthetic selection underlying spinal anesthesia-induced @entity551 in the elderly @entity1 . We conducted a descriptive, observational pilot study to assess the hemodynamic impact of @entity510 with isobaric @entity1343 versus hyperbaric @entity1341 for @entity173 surgery. DESCRIPTION: Hundred twenty ASA status I-IV @entity1 aged 65 and older undergoing @entity173 surgery were enrolled. The primary objective of our study was to compare hemodynamic effects based on systolic blood pressure (SBP) and dyastolic blood pressure (DBP) values, heart rate (HR) and hemoglobin (Hb) and respiratory effects based on partial @entity26 saturation (SpO2%) values. The secondary objective was to assess potential adverse events with the use of @entity1343 versus @entity1341 . Assessments were performed preoperatively, at 30 minutes into surgery, at the end of anesthesia and at 48 hours and 6 months after surgery. Among intraoperative events, the incidence of @entity551 was statistically significantly higher (p <0.05) in group BUPI (38.3%) compared to group LEVO (13.3%). There was a decrease (p <0.05) in systolic blood pressure (SBP) and diastolic blood pressure (DBP) at 30 minutes intraoperatively (19% in group BUPI versus 17% in group LEVO). SpO2% increased at 30 minutes after anesthesia onset (1% in group BUPI versus 1.5% in group LEVO). Heart rate (HR) decreased at 30 minutes after anesthesia onset (5% in group BUPI versus 9% in group L). Hemoglobin (Hb) decreased from time of operating room (OR) admission to the end of anesthesia (9.3% in group BUPI versus 12.5% in group LEVO). The incidence of red blood cell (RBC) transfusion was 13.3% in group BUPI versus 31.7% in group LEVO, this difference was statistically significant. Among postoperative events, the incidence of @entity712 ( @entity712 ) was significantly higher in group BUPI (8,3%). At 6 months after anesthesia, no differences were found. CONCLUSIONS: Given the hemodynamic stability and lower incidence of intraoperative @entity551 observed, @entity1343 could be the agent of choice for @entity510 in elderly @entity1 .

Hemodynamic impact of isobaric @entity1343 versus hyperbaric @entity1341 for @entity510 in XXXX aged 65 and older undergoing hip surgery.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity712 :: ('MESH:D006333', 'Disease') :: ['congestive heart failure', 'CHF'] @entity510 :: ('MESH:D013345', 'Disease') :: ['subarachnoid anesthesia'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity1341 :: ('MESH:D002045', 'Chemical') :: ['bupivacaine'] @entity173 :: ('MESH:D006620', 'Disease') :: ['hip fracture'] @entity1343 :: ('MESH:C476513', 'Chemical') :: ['levobupivacaine'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension']
@entity1 :: (9606,Species) :: ['patients']
