OBJECTIVE: To identify risk factors and mycological characteristics of @entity4963 in Pediatric ICU of a tertiary-care hospital. METHODS: @entity1 were screened for @entity4963 by blood culture. Recovered isolates were speciated and subjected to antifungal susceptibility testing. For every candidemic @entity1 , three controls were matched for age, underlying diagnosis and period of hospitalization. Premature neonates were also matched for birth-weight. Proportion of cases and controls on specific antibiotics or indwelling devices was compared using Chi-square test, while unpaired t-test was used for comparing the number of antibiotics used and the number of days of antibiotic administration. Concordance between susceptibility testing methods was evaluated using Chi-square test. RESULTS: Significantly wider spectrum of antibiotic coverage was observed among the 28 candidemic @entity1 . While every patient received antibiotic against enteric gram-negative bacilli, antibiotic usage for additional groups of microorganisms was significantly higher among cases. Association of @entity4963 with increasing use of indwelling devices was also observed. Endogenous colonization was higher in candidemic @entity1 . @entity5132 was the commonest species (n   =   18), followed by @entity9841 (n   =   7). @entity2380 and @entity3102 resistance was observed in 10.7  % cases. CONCLUSIONS: This information on pediatric @entity4963 could be used to devise locally-tailored strategies for identifying at-risk @entity1 , underline the importance of routine antifungal susceptibility testing and formulate appropriate guidelines for management.

Antibiotic Overuse as a Risk Factor for XXXX in an Indian Pediatric ICU.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'infants'] @entity9841 :: ('5482', 'Species') :: ['C. tropicalis'] @entity2380 :: ('MESH:D015725', 'Chemical') :: ['Fluconazole'] @entity3102 :: ('MESH:D007654', 'Chemical') :: ['ketoconazole'] @entity4963 :: ('MESH:D058387', 'Disease') :: ['candidemia'] @entity5132 :: ('5476', 'Species') :: ['Candida albicans']
@entity4963 :: (MESH:D058387,Disease) :: ['Candidemia']
