BACKGROUND: Video-assisted thoracoscopic surgery (VATS) for clinical stage I @entity1149 ( @entity1149 ) has been widely used as a less invasive surgical procedure, but the resection method is still controversial. We retrospectively compared the surgical outcomes of lobectomy, segmentectomy and wedge resection. @entity1 AND METHODS: A total of 411 @entity1 with clinical stage I @entity1149 who underwent VATS (218 males and 193 females, aged 69.3 years; 345 @entity420 , 57 @entity957 , and 9 others) were investigated. The surgical procedure was lobectomy in 289, segmentectomy in 38, and wedge resection in 84. Surgical outcomes were compared among these 3 groups. RESULTS: Demographic characteristics showed that the rate of elderly and male @entity1 was higher in the wedge resection group. The 5-year survival rates for the lobectomy, segmentectomy, and wedge resection groups were 82.1, 87.2, and 55.4%, respectively. In the wedge resection group, the 5-year survival rate was 83.3% in @entity1 undergoing intentional low-risk operations for small @entity5 with ground glass opacity, and 41.1% in those undergoing conservative high-risk operations because of comorbidities. Using Cox's proportional multivariate analysis and sex differences, histology, and @entity5 size as co-influential factors, the surgical procedure was found to be a significantly poor prognostic factor, and the hazard ratio of wedge resection relative to lobectomy was 4.30. CONCLUSION: The outcomes of VATS lobectomy and segmentectomy procedures for clinical stage I @entity1149 were equivalent, while the outcome for VATS wedge resection was inferior. VATS wedge resection for clinical stage I @entity1149 should be carefully indicated and requires adequate @entity1 selection.

Comparison of the surgical outcomes of thoracoscopic lobectomy, segmentectomy, and wedge resection for clinical stage I XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinomas'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small cell lung cancer'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinomas']
@entity1149 :: (MESH:D002289,Disease) :: ['non-small cell lung cancer']
