BACKGROUND: Nasal @entity1412 demonstrates histological features of epithelial remodeling and variable inflammatory cellular infiltration. We studied a large series of Chinese @entity480 ( @entity480 ) samples to characterize these histological features and their associations with clinical characteristics. METHODS: A detailed histological study of @entity1412 was performed employing various histopathological techniques. A total of 153 intraoperative @entity480 biopsies were analyzed histologically. Sections were examined under microscopy to determine the percentages of different types of inflammatory cells, and types of epithelial remodeling. Two systems of subtyping NPs based on inflammatory cell infiltration were assessed. These were correlated with @entity1 characteristics. RESULTS: Epithelial remodeling patterns include @entity2543 (87.8% of specimens), @entity1373 (53.2%), and @entity1544 (44.6%). Smoking was a strong independent association of @entity1544 (adjusted odds ratio [OR] 9.9; 95% confidence interval [CI], 4.2 to 22.9; p < 0.01). The most common inflammatory cells were neutrophils (median of 12.8%) and CD8+ T cells (12.8%), followed by macrophages (11.0%), CD4+ T cells (9.7%), @entity1712 (8.6%), and mast cells (7.6%). We defined 2 systems to classify NPs based on proportions of @entity1712 and neutrophils. The majority of @entity480 samples were neutrophilic. The first classification system has greater histological correlation. Based on the first classification, @entity1412 was associated with @entity2543 (OR 3.7, p = 0.019) and @entity1373 (OR 3.4, p < 0.001). CONCLUSION: The majority of Chinese NPs are neutrophilic and @entity2543 is the most common pattern of epithelial remodeling. We show for the first time that smoking has a strong association with @entity1544 in @entity1412 .

Smoking is an independent association of @entity1544 in Chinese XXXX .

@entity1 :: ('9606', 'Species') :: ['patient'] @entity1712 :: ('MESH:D004802', 'Disease') :: ['eosinophils'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['goblet cell hyperplasia'] @entity1544 :: ('MESH:D018307', 'Disease') :: ['squamous metaplasia'] @entity2543 :: ('MESH:D017573', 'Disease') :: ['epithelial hyperplasia'] @entity1412 :: ('MESH:D011125', 'Disease') :: ['polyposis', 'nasal polyposis', 'eosinophilic nasal polyposis'] @entity480 :: ('MESH:D009298', 'Disease') :: ['nasal polyp', 'NP']
@entity480 :: (MESH:D009298,Disease) :: ['nasal polyps']
