OBJECTIVES: To investigate the effects of intravenous iloprost on @entity120 ( @entity120 ) in @entity1 undergoing congenital heart surgery. METHODS: In this prospective, randomized study, the study group (n = 15) received a continuous infusion of iloprost (2.0 ng/kg/min) that was delivered immediately after weaning from cardiopulmonary bypass and continued for 72 h postoperatively. @entity1 in the control group (n = 12) were managed conventionally. The groups were compared in terms of postoperative data, including systolic and mean pulmonary artery (PA) pressures, PA/systemic pressure ratio, @entity880 level, @entity120 crisis, ventilation time, reintubation and lengths of @entity1213 ( @entity1213 ) and hospital stay. Transthoracic echocardiography was used to assess PA pressures at 1 day, 7 days and 30 days after surgery. RESULTS: No mortality occurred. @entity120 crisis occurred in 2 (16.6%) @entity1 in the control group and 4 (26.7%) @entity1 in the study group (P = 0.53). Postoperative PA pressures and PA/systemic pressure ratios were similar between the groups (P > 0.05). The durations of @entity1213 (P = 0.40) and hospital (P = 0.98) stays were similar between the groups. Echocardiographic studies demonstrated a significant @entity551 in the control (P = 0.001) and study (P = 0.0001) groups. However, no significant change was observed between the groups (P > 0.05). The Tukey multiple comparison test showed a significant decrease in PA pressures at each follow-up in both groups (P < 0.05). CONCLUSIONS: Intravenous iloprost demonstrated no additional benefit over the conventional management of @entity1 with @entity120 after repair of @entity4615 . Clinicians may prefer other alternative agents in @entity1 with a high risk of @entity120 crisis.

The effect of intravenous iloprost on XXXX after paediatric congenital heart surgery.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'infants'] @entity120 :: ('MESH:D006976', 'Disease') :: ['PAH', 'pulmonary artery hypertension'] @entity4615 :: ('MESH:C538262', 'Disease') :: ['intracardiac defects'] @entity1213 :: ('MESH:D012555', 'Disease') :: ['intensive care unit', 'ICU'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity551 :: ('MESH:D007022', 'Disease') :: ['decrease in postoperative PA pressures']
@entity120 :: (MESH:D006976,Disease) :: ['pulmonary artery hypertension']
