INTRODUCTION: Orthodontic @entity1 usually complain about masticatory limitations associated with the activation of fixed appliances. The aim of this investigation was to evaluate whether @entity158 reflects differences in the objective evaluation of mastication and in the levels of proinflammatory cytokines in the crevicular fluid of @entity1 undergoing orthodontic treatment. METHODS: Twenty @entity1 with @entity3232 requiring orthodontic treatment were included in this prospective study. Their @entity158 experience, masticatory performance, and levels of @entity1356 and @entity1421 in crevicular fluid were evaluated at 3 times: before bracket placement, 24  hours after archwire placement, and 30  days after the initial appointment. All variables were compared with those of a control group of 25 subjects with normal occlusion. RESULTS: The masticatory performance of the @entity1 was significantly reduced at 24  hours after bracket placement, the period in which they reported higher values of @entity158 and had higher levels of @entity1356 . The levels of @entity1421 did not change in the periods evaluated, and there were no correlations between the levels of cytokines and the functional limitations observed. The only significant correlation was between @entity158 and decreased masticatory performance. CONCLUSIONS: The masticatory performance of orthodontic @entity1 is significantly reduced only during the period of greatest @entity158 . However, these alterations did not correlate with any measurement of @entity1356 or @entity1421 in the crevicular fluid, suggesting that these solitary measurements are inadequate to predict the @entity158 and masticatory limitations experienced by @entity1 undergoing orthodontic treatment.

Association among XXXX , masticatory performance, and proinflammatory cytokines in crevicular fluid during orthodontic treatment.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1356 :: ('3553', 'Gene') :: ['interleukin 1-beta'] @entity1421 :: ('MESH:D015232', 'Chemical') :: ['prostaglandin E2'] @entity3232 :: ('MESH:D008310', 'Disease') :: ['malocclusions'] @entity158 :: ('MESH:D010146', 'Disease') :: ['temporary pain', 'pain', 'orthodontic pain']
@entity158 :: (MESH:D010146,Disease) :: ['pain']
