We present a rare case of colorectalcarcinoma in which @entity1269 was the initialsymptom. A 75-year-old @entity1 presented with incomplete left-sided @entity1269 . Brain magnetic resonance imaging(MRI)revealed a 13-mm mass in the right frontal lobe; the mass was resected via craniotomy. Pathological findings, which included the results of immunohistochemical analysis, indicated brain @entity3 from @entity14 . Colonoscopy revealed advanced @entity694 in the ascending colon, and computed tomography(CT)did not revealany extracranialmetastases. Left-sided hemicolectomy was performed. Whole-brain radiotherapy was scheduled, but before initiation of the therapy, metastases were detected in the neck lymph node and right arm skin, and the brain metastases relapsed. The relapsed brain metastatic lesions were resected, and radiotherapy was administered to the whole brain and the severely @entity158 site of skin @entity3 . However, the @entity1 died 201 days after presentation. Historically, systemic chemotherapy was considered ineffective for metastatic @entity1313 , and the standard treatments for brain @entity3 were surgery and radiotherapy. Although recent advances in systemic chemotherapy for @entity14 have resulted in improved @entity1 survival, @entity1 with brain metastases from @entity14 still have a poor prognosis. Modern chemotherapeutic agents, including molecularly targeted agents such as bevacizumab, should be validated for the management of brain metastases.

[ @entity14 with XXXX due to isolated brain metastases as an initial symptom - a case report].

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'patient'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['brain tumor'] @entity1269 :: ('MESH:D010291', 'Disease') :: ['hemiparesis'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity158 :: ('MESH:D010146', 'Disease') :: ['painful'] @entity694 :: ('MESH:D003110', 'Disease') :: ['colon cancer']
@entity1269 :: (MESH:D010291,Disease) :: ['hemiparesis']
