OBJECTIVE: The aim of the study was to evaluate the impact of the clinical significance of @entity263 (PC) on @entity1349 ( @entity1349 ) after radical cystoprostatectomy (RC) for @entity150 ( @entity150 ). METHODS: A total of 822 consecutive @entity1 underwent RC in 3 academic centers between 1996 and 2011. The clinical significance of incidental PC was determined according to the Epstein criteria. The Kaplan-Meier analysis with log-rank was used to investigate the impact of PC on @entity1349 and univariate and multivariate Cox regression analyses for risk factors of @entity1349 . The median follow-up was 36 months (interquartile range 10-49). RESULTS: Of the 822 @entity1 , 117 (14.2%) had clinically significant, 243 (29.6%) insignificant and 462 (56.2) no PC at RC. @entity1 with PC were at higher risk for @entity3 ( @entity3 ) of @entity150 compared to @entity1 without PC (p < 0.001). The 5-year @entity1349 for @entity1 with clinically significant, insignificant and no PC was 33.3, 51.3 and 51.5%, respectively (p = 0.050). In the subgroup of pN0 @entity1 (n = 601), clinically significant PC was significantly associated with inferior @entity1349 (p = 0.044) but not in multivariable analysis (p = 0.46). CONCLUSIONS: We did not find the clinical significance of incidental PC to be an independent predictor. However, the positive correlation between incidental PC and @entity3 of @entity150 deserves further investigation.

Prognostic Significance of Incidental @entity263 at Radical Cystoprostatectomy for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Men', 'men'] @entity263 :: ('MESH:D011471', 'Disease') :: ['incidental prostate cancer'] @entity150 :: ('MESH:D001749', 'Disease') :: ['BC', 'bladder cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['lymphovascular invasion', 'LVI'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity150 :: (MESH:D001749,Disease) :: ['Bladder Cancer']
