In a study carried out in the Ghassreghand Division (Baluchistan, Iran) from March through November 1995, efficacy of @entity317 -impregnated bednets was compared to that of untreated nets, in relation to @entity311 control. Ten villages with a total population of 4,572 and 3 villages with a total population of 1,935 were used as treatment and control, respectively. The collection, impregnation (target dosage of 40 mg active ingredient [AI]/m2), and redistribution of the nets (9% nylon, 52% light @entity2708 , 30% medium @entity2708 , and 9% heavy @entity2708 ), carried out in mid-April, were done by local health workers, supervised by the senior research staff. Anopheles culicifacies was considered to be the main vector of @entity311 in the named area. This species is mainly zoophilic, endophilic, and exophagic. The initial uptake of the insecticide was lower than the target dosage, with high variation (nylon, 12.5 +/- 5.4 mg AI/m2; light @entity2708 , 33.3 +/- 26.1 mg AI/m2; medium @entity2708 , 25.9 +/- 20 mg AI/m2; heavy @entity2708 , 17.6 +/- 12.5 mg AI/m2). The use of impregnated mosquito nets (used primarily outside) had no significant effect on the incidence of @entity311 . No difference was detected in the parasite density of @entity1 with positive slides. No significant effect was observed in the parous rate, @entity1 blood index, and sporozoite rate of anopheline vectors. Only the indoor resting densities of An. culicifacies and other @entity311 vectors were drastically reduced after the introduction of the @entity317 -impregnated nets into the treatment villages. The residual activity of @entity317 was lower than expected. The mortality of anophelines brought in contact with the treated nets for 3 min in bioassays dropped to less than 55% in 3 months. The loss of chemical activity was greatest for the light @entity2708 nets, followed by the medium @entity2708 nets. @entity317 -treated nets were mildly irritating to host-seeking female anophelines in the laboratory. The protective rate of impregnation (all fabric kinds included) in preventing female mosquitoes from biting through the impregnated nets was initially 5-6 times that of the nonimpregnated nets. The study did not detect any significant difference between the use of untreated versus impregnated bednets in the Ghassreghand area. In planning future medium-scale trials, comparison of new compounds and formulations to the more widely used @entity312 such as @entity315 and @entity316 is highly recommended.

XXXX (EW 050)-impregnated bednets in a @entity311 control program in Ghassreghand (Baluchistan, Iran).

@entity317 :: ('MESH:C052570', 'Chemical') :: ['Cyfluthrin', 'cyfluthrin'] @entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity2708 :: ('3635', 'Species') :: ['cotton'] @entity312 :: ('MESH:D011722', 'Chemical') :: ['pyrethroids'] @entity316 :: ('MESH:C017180', 'Chemical') :: ['deltamethrin'] @entity315 :: ('MESH:D026023', 'Chemical') :: ['permethrin'] @entity311 :: ('MESH:D008288', 'Disease') :: ['malaria']
@entity317 :: (MESH:C052570,Chemical) :: ['Cyfluthrin']
