OBJECTIVE: To study the accuracy of CT for staging T3a (TNM 2009) @entity1358 ( @entity1358 ). METHODS: Unenhanced and nephrographic phase CT studies of 117 @entity1 (male:female   =   82:35; age range, 21-86   years) with T1-T3a @entity1358 were independently reviewed by 2 readers. The presence of sinus or perinephric fat, or @entity703 characteristics were noted. RESULTS: Median (range) @entity5 size was 5.5 (0.9-19.0)   cm; and 46 (39%), 16 (14%) and 55 (47%) @entity5 were @entity2558 , pT2 and pT3a @entity1358 , respectively. The sensitivity/specificity for sinus fat, perinephric fat and @entity8 were 71/79%, 83/76% and 59/93% (Reader 1) and 88/71%, 68/72% and 69/91% (Reader 2) with k   =   0.41, 0.43 and 0.61, respectively. Sinus fat invasion was seen in 47/55 (85%) cases with T3a @entity1358 vs 16/55 (29%) and 33/55 (60%) for perinephric fat and @entity8 . Tumour @entity39 , irregularity of @entity5 edge and direct @entity5 fat increased the odds of local invasion [odds ratio (OR), 2.5-3.7; p   <   0.05; k   =   0.42-0.61]. Stage T3a @entity5 were centrally located (OR, 3.9; p   =   0.0009). CONCLUSION: Stage T3a @entity1358 was identified with a sensitivity of 59-88% and specificity of 71-93% (k   =   0.41-0.61). Sinus fat invasion was the most common invasive feature. ADVANCES IN KNOWLEDGE: Centrally situated @entity703 with an irregular @entity5 edge, inseparable from @entity50 and CT features of @entity5 @entity39 should alert the reader to the possibility of Stage T3a @entity1358 (OR, 2.5-3.9).

Stage T3a @entity1358 : staging accuracy of CT for sinus fat, perinephric fat or XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2558 :: ('58492', 'Gene') :: ['pT1'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal vein invasion'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumours', 'tumour contact with perirenal fascia or sinus', 'tumour'] @entity1358 :: ('MESH:D002292', 'Disease') :: ['renal cell carcinoma', 'RCC'] @entity50 :: ('MESH:D012851', 'Disease') :: ['sinus structures or the perirenal fascia'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal tumours', 'renal vein invasion and tumour']
@entity8 :: (MESH:D007674,Disease) :: ['renal vein invasion']
