BACKGROUND: Cymbopogon citratus (Poaceae) a tropical perennial herb plant that is widely cultivated to be eaten either fresh with food or dried in tea or soft drink has been reported to possess a number of medicinal and aromatic properties. This study aimed at evaluating the protective effects of C. citratus aqueous extract against @entity99 induced by @entity273 ( @entity274 ), in male @entity35 . MATERIALS AND METHODS: Twenty-five @entity35 were randomly divided into five different groups of five animals in each group; (1) Control. (2) Received @entity274 (0.5%) with drinking water. (3), and (4) received @entity274 and C. citratus (100 mg  kg(-1) b wt), @entity620 (250 mg  kg(-1) b wt) respectively. (5), was given C. citratus alone. The treatments were administered for 30 days. Blood samples were collected and serum was used for biochemical assay including liver enzymes activities, total protein, total @entity648 and @entity1234 , @entity2041 in serum and liver homogenates. Liver was excised and routinely processed for histological examinations. RESULTS: C. citratus attenuated @entity409 due to @entity274 administration as indicated by the significant reduction (p<0.05), in the elevated levels of ALT, AST, @entity6032 , LDH, @entity1906 , and @entity1865 in serum and liver homogenates; increase in TP and @entity2197 levels in serum and liver homogenates; and improvement of liver histo-pathological changes. These effects of the extract were similar to that of @entity620 which used as antioxidant reference. CONCLUSION: C. citratus could effectively ameliorate @entity274 -induced oxidative stress and prevent @entity99 in male @entity35 .

Hepatoprotective effect of cymbopogon citratus aqueous extract against @entity273 -induced XXXX in male @entity35 .

@entity6032 :: ('114108(Tax:10116)', 'Gene') :: ['ALP'] @entity274 :: ('CHEBI:16240', 'Chemical') :: ['H2O2'] @entity620 :: ('MESH:D001205', 'Chemical') :: ['vitamin C'] @entity648 :: ('MESH:D001663', 'Chemical') :: ['bilirubin'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver damage'] @entity2041 :: ('MESH:D005978', 'Chemical') :: ['glutathione'] @entity2197 :: ('CHEBI:16856', 'Chemical') :: ['GSH'] @entity273 :: ('MESH:D006861', 'Chemical') :: ['hydrogen peroxide'] @entity1234 :: ('MESH:D008315', 'Chemical') :: ['malonaldehyde'] @entity1906 :: ('MESH:D014390', 'Disease') :: ['TB'] @entity35 :: ('10116', 'Species') :: ['rats'] @entity99 :: ('MESH:D056486', 'Disease') :: ['liver injury'] @entity1865 :: ('CHEBI:566274', 'Chemical') :: ['MDA']
@entity99 :: (MESH:D056486,Disease) :: ['liver injury']
