BACKGROUND: Recently, topical steroid application has been shown by a small number of studies to be an effective alternative to circumcision for the treatment of @entity5372 . However, only potent or very potent corticosteroids have been more thoroughly studied in this treatment option. A prospective study was conducted to determine whether comparable results could be achieved using a weaker steroid cream. METHODS: @entity1 , 3-13 years of age, with non-retractable foreskin due to a tight ring at the tip were offered the regimen of twice-daily preputial retraction and topical application of 0.02% @entity2995 cream. The degree of preputial retractability was assessed at presentation and at 4 and 6 weeks of treatment. Success was defined as full retraction or free retraction up to agglutination of the foreskin to the glans. RESULTS: Eighty-three @entity1 completed the treatment. Successful retraction was achieved in 48/83 (58%) @entity1 after 4 weeks and 70/83 (84%) @entity1 after 6 weeks of application. The overall response rate aggregated from six published series using 0.05% @entity5935 was 87% at 4 weeks and 90% on completion of treatment. Thus, the results appear inferior when analysed at 4 weeks but compare favourably with those reported for a more potent @entity134 on completion of the full course of treatment. CONCLUSIONS: Even though the @entity2713 cream used in the present study is less potent than the more commonly used 0.05% @entity17834 cream, it could effect comparable improvements in foreskin retractability after 6 weeks of treatment.

Treatment of childhood XXXX with a moderately potent topical steroid.

@entity1 :: ('9606', 'Species') :: ['Boys', 'patients', 'boys'] @entity2995 :: ('MESH:D014222', 'Chemical') :: ['triamcinolone acetonide'] @entity17834 :: ('CHEBI:31277', 'Chemical') :: ['betamethasone valerate'] @entity5935 :: ('MESH:D001623', 'Chemical') :: ['betamethasone'] @entity134 :: ('CHEBI:35341', 'Chemical') :: ['steroid'] @entity5372 :: ('MESH:D010688', 'Disease') :: ['phimosis'] @entity2713 :: ('MESH:D014221', 'Chemical') :: ['triamcinolone']
@entity5372 :: (MESH:D010688,Disease) :: ['phimosis']
