OBJECTIVES: The aim of this study is to investigate the association between age, gender, body-mass index, smoking behavior, orthopedic comorbidity, neurologic comorbidity, @entity299 , vascular comorbidity, @entity849 , internal comorbidity and Initial @entity613 Distance during and after Supervised Exercise Therapy at 1, 3, 6 and 12 months in a large sample of @entity1 with @entity613 . METHODS: Data was prospectively collected in standard physiotherapy care. @entity1 received Supervised Exercise Therapy according to the guideline @entity613 of the Royal Dutch Society for Physiotherapy. Three-level mixed linear regression analysis was carried out to analyze the association between @entity1 characteristics, comorbidities and Initial @entity613 Distance at 1, 3, 6 and 12 months. RESULTS: Data from 2995 @entity1 was analyzed. Results showed that being female, advanced age and a high body-mass index were associated with lower Initial @entity613 Distance at all-time points (p = 0.000). Besides, a negative association between @entity299 and Initial @entity613 Distance was revealed (p = 0.011). The interaction time by age, time by body-mass index and time by vascular comorbidity were significantly associated with Initial @entity613 Distance (p <= 0.05). Per year increase in age (range: 33-93 years), the @entity613 Distance was 8m after 12 months of Supervised Exercise Therapy. One unit increase in body-mass index (range: 16-44 kg/m2) led to 10m less improvement in Initial @entity613 Distance after 12 months and for vascular comorbidity the reduction in improvement was 85m after 12 months. CONCLUSIONS: This study reveals that females, @entity1 at advanced age, @entity1 with a high body-mass index and @entity299 are more likely to show less improvement in @entity613 ( @entity613 ) after 1, 3, 6 and 12 months of Supervised Exercise Therapy. Further research should elucidate treatment adaptations that optimize treatment outcomes for these subgroups.

XXXX Characteristics and Comorbidities Influence Walking Distances in Symptomatic Peripheral Arterial Disease: A Large One-Year Physiotherapy Cohort Study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity849 :: ('MESH:D011666', 'Disease') :: ['pulmonic comorbidity'] @entity613 :: ('MESH:D007383', 'Disease') :: ['Initial Claudication Distances', 'Claudication', 'reduction in Initial Claudication', 'Intermittent Claudication', 'ICD'] @entity299 :: ('MESH:D006331', 'Disease') :: ['cardiac comorbidity']
@entity1 :: (9606,Species) :: ['Patient']
