UNASSIGNED: @entity281 undetectable by microscopy but detectable by Polymerase Chain Reaction (PCR) (submicroscopic @entity311 ) are common in endemic areas like Ghana. Submicroscopic @entity311 has been linked with severe pregnancy outcomes as well as contributing to @entity311 transmission. In this cross-sectional study 872 consenting pregnant @entity1 (gestation >=  20 weeks) were recruited from 8 hospitals in Central Region, Ghana, between July and December 2009. @entity281 was detected by microscopy and PCR. Haemoglobin was measured and @entity417 was defined as haemoglobin lower than 11   g/dL. Majority of the @entity1 , 555 (63.6%), were Intermittent Preventive Treatment in Pregnancy with @entity1484 (IPTp-SP) users while 234 (36.4%) were nonusers. The prevalence of @entity311 by microscopy was 20.9% (182/872) and 9.7% (67/688) of microscopy negative @entity1 had submicroscopic @entity311 . IPTp-SP usage significantly (odds ratio = 0.13, 95% confidence interval = 0.07-0.23, p = 0.005) reduced the prevalence of submicroscopic @entity311 as more nonusers (51/234) than users (16/454) were PCR positive. After controlling for other variables the effect of IPTp-SP remained statistically significant (odds ratio = 0.11, 95% confidence interval = 0.02-0.22, p = 0.006). These results suggest that Intermittent Preventive Treatment with @entity16945 - @entity4765 is useful in the reduction of submicroscopic @entity311 in pregnancy.

Effectiveness of Intermittent Preventive Treatment in Pregnancy with @entity16945 - XXXX against Submicroscopic falciparum Malaria in Central Region, Ghana.

@entity1 :: ('9606', 'Species') :: ['women'] @entity1484 :: ('MESH:C001205', 'Chemical') :: ['Sulphadoxine-Pyrimethamine'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anaemia'] @entity16945 :: ('CHEBI:9329', 'Chemical') :: ['Sulphadoxine'] @entity281 :: ('MESH:D007239', 'Disease') :: ['Malaria infections', 'Malaria infection'] @entity311 :: ('MESH:D008288', 'Disease') :: ['malaria'] @entity4765 :: ('MESH:D011739', 'Chemical') :: ['Pyrimethamine']
@entity4765 :: (MESH:D011739,Chemical) :: ['Pyrimethamine']
