OBJECTIVE: To report a case of drug-induced @entity221 associated with @entity500 treatment in a @entity1 with @entity370 . CASE SUMMARY: A 52-year-old @entity1 with @entity10070 presented to the emergency department with a 1-day history of @entity221 (temperature 39.9   C), chills, @entity390 , and @entity391 . One week earlier, @entity500 50 mg/day had been started for worsening @entity1353 . The @entity1 was admitted and evaluated for acute infectious processes. All of his home medications ( @entity6383 , @entity229 , @entity5023 / @entity10453 , @entity5753 , @entity10112 , @entity2492 , @entity7923 , @entity3045 ), except @entity229 , were held. Results of chest X-ray, viral cultures, and urine and blood cultures revealed no source of @entity281 . The @entity1 's temperature returned to normal within 30 hours after discontinuation of @entity500 ; rechallenge was not performed. DISCUSSION: Fever as an adverse drug reaction is often unrecognized, particularly in medically complex @entity1 . @entity500 has been reported to cause @entity221 in @entity1 with @entity29 and in those with @entity309 ; to our knowledge, there have been no previous reports documenting @entity500 -induced @entity221 in @entity1 with @entity370 . The chronological course of febrile response and defervescence is highly suggestive of drug-induced @entity221 . CONCLUSIONS: The rapid resolution of @entity221 after discontinuation of @entity500 suggests that it was the likely source of @entity221 in this @entity1 . If @entity500 is increasingly prescribed in @entity1 with @entity370 , @entity221 as an adverse reaction may become more common.

@entity500 -induced XXXX in @entity370 .

@entity1 :: ('9606', 'Species') :: ['patient', 'man', 'patients'] @entity390 :: ('MESH:D009325', 'Disease') :: ['nausea'] @entity500 :: ('MESH:D001379', 'Chemical') :: ['Azathioprine', 'azathioprine'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['dyspnea'] @entity309 :: ('MESH:D001172', 'Disease') :: ['rheumatoid arthritis'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity3045 :: ('MESH:D000420', 'Chemical') :: ['albuterol'] @entity391 :: ('MESH:D014839', 'Disease') :: ['vomiting'] @entity7923 :: ('MESH:C073007', 'Chemical') :: ['ibandronate'] @entity29 :: ('MESH:D015212', 'Disease') :: ['inflammatory bowel disease'] @entity6383 :: ('MESH:D006886', 'Chemical') :: ['hydroxychloroquine'] @entity5753 :: ('MESH:D008148', 'Chemical') :: ['lovastatin'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity10112 :: ('MESH:C064276', 'Chemical') :: ['pantoprazole'] @entity10453 :: ('MESH:C057823', 'Chemical') :: ['salmeterol'] @entity370 :: ('MESH:D012507', 'Disease') :: ['sarcoidosis'] @entity5023 :: ('MESH:C065382', 'Chemical') :: ['fluticasone'] @entity221 :: ('MESH:D005334', 'Disease') :: ['drug fever', 'fever'] @entity10070 :: ('MESH:D017565', 'Disease') :: ['pulmonary sarcoidosis'] @entity2492 :: ('MESH:C049109', 'Chemical') :: ['zolpidem']
@entity221 :: (MESH:D005334,Disease) :: ['fever']
