UNASSIGNED: Purpose To evaluate surgical success after pulmonary endarterectomy ( @entity3587 ) by means of cardiopulmonary magnetic resonance (MR) imaging. Materials and Methods In this institutional review board-approved study, 20 @entity1 with chronic @entity120 were examined at 1.5 T with a dynamic contrast material-enhanced three-dimensional fast low-angle shot sequence before and 12 days after @entity3587 (25th-75th percentile range, 11-16 days). Lung segments were evaluated visually before @entity3587 for parenchymal hypoperfused segments. Pulmonary blood flow (PBF), first-pass bolus kinetic parameters, and biventricular mass and function were determined. Mean pulmonary artery pressure ( @entity7215 ) and 6-minute walking distance were measured before and after @entity3587 . The Shapiro-Wilk test, paired two-sided Wilcoxon rank sum test, Spearman    correlation, and multiple linear regression analysis were performed. Results Two weeks after @entity3587 , regional PBF increased 66% in the total lung from 32.7 to 54.2 mL/min/100 mL (P = .0002). However, after adjustment for cardiac output, this change was not evident anymore (increase of 7% from 7.03 to 7.54 mL/min/100 mL/L/min, P = .1). Only in the lower lobes, a significant increase in PBF after cardiac output adjustment remained: a 16% increase in the right lower lobe from 7.53 to 8.71 mL/min/100 mL (P = .01) and a 14% increase in the left lower lobe from 7.42 to 8.47 mL/min/100 mL/L/min (P < .05). Right ventricular mass and function also improved. @entity7215 decreased from 46 to 24 mm Hg (P < .0001). Six-minute walking distance increased from 390 to 467 m (P = .02) 5 months after @entity3587 . Percentage change of @entity7215 and PBF in the lower lobe tended to be significant predictors of percentage change in 6-minute walking distance (b = -1.79 [P = .054] and b = 0.45 [P = .076], respectively) in multiple linear regression analysis. Conclusion Improvement of PBF after @entity3587 was observed predominantly in the lower lungs, and the magnitude of improvement of PBF in the lower lobes correlated with the improvement in exercise capacity, reflecting surgical success. (  ) RSNA, 2016.

MR Imaging-derived Regional Pulmonary Parenchymal Perfusion and Cardiac Function for Monitoring @entity1 with Chronic XXXX before and after Pulmonary Endarterectomy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity120 :: ('MESH:D006976', 'Disease') :: ['thromboembolic pulmonary hypertension'] @entity3587 :: ('3888', 'Species') :: ['PEA'] @entity7215 :: ('19012(Tax:10090)', 'Gene') :: ['mPAP']
@entity120 :: (MESH:D006976,Disease) :: ['Thromboembolic Pulmonary Hypertension']
