PURPOSE: To determine the relationship between the blood flow parameters of the optic disc rim and the @entity227 . DESIGN: Observational cross-sectional study. METHODS: Tissue blood flow in the neuroretinal rim within the optic disc was determined with the Heidelberg retina flowmeter(HRF) in 54 eyes of 54 @entity1 with normal tension @entity726 (NTG). @entity1 were selected whose @entity227 were confined to either the superior or inferior hemifield. Blood flow measurements were made in a 10 degrees x 2.5 degrees area of the superior and inferior neuroretinal rim within the optic disc. The @entity450 ( @entity450 ) was calculated by the automatic full-field perfusion image analyzer program, and the ratio of the @entity450 in the superior to the inferior rim areas (the S/I ratio) was calculated from the same HRF image in order to minimize the variation of measurement condition. RESULTS: Inferior rim blood flow is less than superior rim blood flow in @entity1 with superior hemifield defect, and superior rim blood flow is reduced compared to inferior in @entity1 with @entity75 . The mean S/I ratios of the @entity450 in the @entity1 with superior hemifield defect (1.46, n=37) was significantly higher than that in the @entity1 with @entity75 (0.79, n=17; P<0.0001, Mann-Whitney U-test). CONCLUSIONS: The blood flow in the neuroretinal rim was found to correspond to the regional @entity227 in eyes with NTG. Reductions in flow were associated with reductions in function.

Decreased blood flow at neuroretinal rim of optic nerve head corresponds with @entity227 in eyes with normal tension XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual field defect', 'visual field defects', 'glaucomatous visual field changes'] @entity75 :: ('MESH:D001927', 'Disease') :: ['inferior hemifield defect'] @entity726 :: ('MESH:D005901', 'Disease') :: ['glaucoma'] @entity450 :: ('MESH:D006940', 'Disease') :: ['MBF', 'mean blood flow']
@entity726 :: (MESH:D005901,Disease) :: ['glaucoma']
