Our objective was to find out prevalence of @entity3458 among the population of three districts (Kanker, Dantewada and Raigarh) of Chhattisgarh with clinical and hematological profile of @entity3458 @entity1 . A cross sectional study was done. A total of 15,701 @entity1 collectively from three districts voluntarily attended the mobile camp and were screened for @entity3458 . First solubility test were done and were confirmed by Hb electrophoresis. The prevalence of sickle cell trait (HbAS) was 1,672 (10.6  %), @entity3458 (HbSS) and inconclusive band was 97 (0.66  %). The HbSS and inconclusive band were subjected to HPLC. Among them 12 (0.076  %) cases were double heterozygous for Hb-S and @entity8674 minor (SB+), 2 (0.012  %) cases were double heterozygous for Hb-S and Hb-E (S/HBE), 1 (0.006  %) case was double heterozygous for Hb-S and Hb-D Punjab (S/HBD) and 22 (0.14  %) cases had Hb-S with Hb-F level more than 20  % (SSF). Maximum number of HbSS cases were 13 (2.29  %) out of 567 @entity1 in the age group 0-5  years and HbAS cases were 124 (15.6  %) out of 794 @entity1 in the age group 21-25  years. On comparison between vaso-occlusive and steady state, homozygous @entity1 showed decrease in Hb, HCT, @entity27127 , RBC in vaso-occlusive crises (p  <  0.001) than steady state. Also there was one moderate negative correlation in number of blood transfusion (r  =  0.46) with fetal hemoglobin (HbF) level. @entity1 with high HbF can have severe disease. This happens due to uneven distribution of fetal hemoglobin in F-cells with mean HbF remaining constant but in our study, those who had HbF level above 15-20  % were having fewer crises.

The screening and morbidity pattern of XXXX in chhattisgarh.

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'persons'] @entity27127 :: ('5367', 'Gene') :: ['MCH'] @entity8674 :: ('MESH:D017086', 'Disease') :: ['beta thalassemia'] @entity3458 :: ('MESH:D000755', 'Disease') :: ['sickle cell anemia', 'sickle cell disease']
@entity3458 :: (MESH:D000755,Disease) :: ['sickle cell anemia']
