AIMS: Individuals with @entity6 are susceptible to hypoglycaemia during and after continuous moderate-intensity exercise, but hyperglycaemia during intermittent high-intensity exercise. The combination of both forms of exercise may have a moderating effect on glycaemia in recovery. The aims of this study were to compare the physiological responses and associated glycaemic changes to continuous moderate-intensity exercise vs. continuous moderate-intensity exercise + intermittent high-intensity exercise in athletes with Type 1 @entity6 . METHODS: Interstitial @entity413 levels were measured in a blinded fashion in 11 trained athletes with Type 1 @entity6 during two sedentary days and during 2 days in which 45 min of afternoon continuous moderate-intensity exercise occurred either with or without intermittent high-intensity exercise. The total amount of work performed and the duration of exercise was identical between sessions. RESULTS: During exercise, heart rate, respiratory exchange ratio, @entity26 utilization, ventilation and blood @entity880 levels were higher during continuous moderate-intensity + intermittent high-intensity exercise vs. continuous moderate-intensity exercise (all P < 0.05). Despite these marked cardiorespiratory differences between trials, there was no difference in the reduction of interstitial @entity413 or plasma @entity413 levels between the exercise trials. Nocturnal @entity413 levels were higher in continuous moderate-intensity + intermittent high-intensity exercise and in sedentary vs. continuous moderate-intensity exercise (P < 0.05). Compared with continuous moderate-intensity exercise alone, continuous moderate-intensity + intermittent high-intensity exercise was associated with less post-exercise hypoglycaemia (5.2 vs. 1.5% of the time spent with @entity413 < 4.0 mmol/l) and more post-exercise hyperglycaemia (33.8 vs. 20.4% of time > 11.0 mmol/l). CONCLUSIONS: Although the decreases in @entity413 level during continuous moderate-intensity exercise and continuous moderate-intensity + intermittent high-intensity exercise are similar, the latter form of exercise protects against @entity7965 in athletes with Type 1 @entity6 .

Continuous moderate-intensity exercise with or without intermittent high-intensity work: effects on acute and late glycaemia in athletes with XXXX .

@entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes', 'Type 1 diabetes mellitus'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity7965 :: ('MESH:D006457', 'Disease') :: ['nocturnal hypoglycaemia'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose']
@entity6 :: (MESH:D003920,Disease) :: ['Type 1 diabetes mellitus']
