INTRODUCTION: Although laparoscopic liver resection (LLR) has developed rapidly, its usefulness for the treatment of large @entity5 is less clear, due to concerns about compromising oncological principles and @entity1 safety. The purpose of this study was to explore the feasibility and safety of LLR for the treatment of @entity157 ( @entity157 ) with a @entity5 size larger than 5   cm. @entity1 AND METHODS: From January 2007 to December 2014, we performed LLR in 45 @entity1 with @entity157 with a @entity5 size >= 5   cm. Perioperative outcome, @entity5 recurrence, and overall @entity1 survival were analyzed. RESULTS: Median age was 60 years (interquartile range [IQR] 52-68) and 64.4% (29/45) were male. Seven @entity1 (15.6%) had larger than 10   cm of @entity157 . No operative @entity204 occurred and six of the laparoscopic procedures were converted to open resection (conversion rate 13.3%). Median operation time was 365 minutes (IQR 277-443) and median estimated @entity190 (EBL) was 400.0   mL (IQR 275-600). There was no R1 or R2 resection and median resection margin was 19.0   mm (IQR 8.0-33.0). Complications above Clavien-Dindo classification grade III occurred in four @entity1 (8.9%). The median overall follow-up time was 10.7 month (range 1.1-62.1). One-year recurrence free survival (RFS) and @entity1349 ( @entity1349 ) were 86.0% and 95.5%, and 3-year RFS and @entity1349 were 70.7% and 86.0%. CONCLUSION: LLR appears safe and feasible in @entity1 with @entity157 with a @entity5 size larger than 5   cm. Expansion of indication for LLR in @entity1 with @entity157 may be considered.

Laparoscopic Liver Resection of XXXX with a Tumor Size Larger Than 5   cm: Review of 45 Cases in a Tertiary Institution.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity157 :: ('MESH:D006528', 'Disease') :: ['HCC', 'hepatocellular carcinoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity157 :: (MESH:D006528,Disease) :: ['Hepatocellular Carcinoma']
