We report a 7-year-old @entity1 with @entity9058 and an uncommon @entity455 and @entity227 . She was also verified to be complicated with @entity7092 . The @entity1 was treated with @entity2879 , @entity619 , and @entity205 . During the fifth hospital week, a generalized @entity3173 developed followed by @entity772 . When she regained full consciousness, she complained of a visual disturbance. The ophthalmologic examination showed bilateral extensive @entity1829 with numerous @entity2708 -wool spots, indicative of @entity732 . This is inconsistent with the main finding of previous cases with ocular involvement, namely @entity1829 . @entity227 remained in both eyes even after systemic therapy. An awareness of this rare but serious complication is important because it may be preventable by early institution of chemotherapy. The pathogenesis of the @entity989 is also discussed.

Ocular involvement and XXXX in @entity9058 in association with congenital dyfsfibrinogenemia.

@entity1 :: ('9606', 'Species') :: ['girl', 'patient'] @entity227 :: ('MESH:D014786', 'Disease') :: ['visual sequelae', 'Severely reduced visual acuity and visual field defects'] @entity455 :: ('MESH:D014652', 'Disease') :: ['complication of vascular retinopathy'] @entity7092 :: ('MESH:C562727', 'Disease') :: ['dysfibrinogenemia'] @entity2708 :: ('3635', 'Species') :: ['cotton'] @entity9058 :: ('MESH:D051359', 'Disease') :: ['hemophagocytic lymphohistiocytosis'] @entity772 :: ('MESH:D003128', 'Disease') :: ['deep coma'] @entity2879 :: ('MESH:D005047', 'Chemical') :: ['etoposide'] @entity3173 :: ('MESH:D004830', 'Disease') :: ['tonic-clonic convulsion'] @entity619 :: ('MESH:D003907', 'Chemical') :: ['dexamethasone'] @entity205 :: ('MESH:D016572', 'Chemical') :: ['cyclosporin A'] @entity1829 :: ('MESH:D010211', 'Disease') :: ['retinal edema', 'papilledema'] @entity989 :: ('MESH:D012164', 'Disease') :: ['retinopathy'] @entity732 :: ('MESH:D015356', 'Disease') :: ['vaso-occlusive retinopathy']
@entity227 :: (MESH:D014786,Disease) :: ['visual sequelae']
