@entity6078 ( @entity6078 ) is the most prevalent of the primary @entity465 , and is characterised by low IgG and IgA, and sometimes IgM. There is some evidence of genetic susceptibility, with 20% of @entity1 having a @entity74 with variable expression. It is a @entity74 with protean manifestations, and as a result diagnosis is often delayed until the second or third decade, with resultant irreversible organ damage, in particular @entity4595 . Effective treatment is available with regular 3-4-weekly infusions of immunoglobulin. The mechanism of the @entity465 has not yet been fully elucidated. The majority of @entity1 present with recurrent @entity281 , however, this is a @entity66 and thus presents to physicians in diverse specialties including dermatology. Other clinical features of the disorder include @entity344 , @entity32 , cutaneous features, unusual presentations of enteroviral and @entity9463 , an increased incidence of @entity792 , and a predisposition to @entity706 and @entity5 . Therefore a knowledge of the disorder and appropriate suspicion by all clinicians of the possibility of such rare problems and a consequent low threshold for performing relevant investigations is imperative in allowing early recognition and instituting effective treatment. We describe a case of @entity6078 identified when the @entity1 developed widespread @entity221 . This case is an important example of a possible presentation of @entity6078 within the dermatology clinic and demonstrates that maintaining a high level of clinical suspicion is essential for the diagnosis of the rare primary @entity465 .

A case of common variable XXXX presenting with furunculosis.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['granulomatous inflammation'] @entity9463 :: ('MESH:D009175', 'Disease') :: ['mycoplasma infection'] @entity66 :: ('MESH:D004194', 'Disease') :: ['multisystem disorder'] @entity706 :: ('MESH:D008223', 'Disease') :: ['lymphoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['stomach cancer'] @entity6078 :: ('MESH:D017074', 'Disease') :: ['Common variable immunodeficiency', 'CVID'] @entity221 :: ('MESH:D005334', 'Disease') :: ['skin infection, fever and malaise'] @entity344 :: ('MESH:D005767', 'Disease') :: ['gastrointestinal problems'] @entity281 :: ('MESH:D007239', 'Disease') :: ['sinopulmonary infection'] @entity465 :: ('MESH:D007153', 'Disease') :: ['immunodeficiency', 'immunodeficiencies'] @entity4595 :: ('MESH:D001987', 'Disease') :: ['bronchiectasis'] @entity74 :: ('MESH:D030342', 'Disease') :: ['dominantly inherited disorder', 'heterogeneous disorder'] @entity792 :: ('MESH:D001327', 'Disease') :: ['autoimmunity']
@entity465 :: (MESH:D007153,Disease) :: ['immunodeficiency']
