Nineteen cases of "localized" leishmania @entity3298 without any evidence of @entity234 are reported. Fifteen males and 4 females aged 5 to 30 years have presented with localized lymphadenopathy of up to 3 months duration. The disease has a seasonal incidence of late summer to mid-winter. @entity4536 even when present, usually was overlooked. Lesions of @entity4536 were absent in 3; healed in 1; small, similar to insect bites in 5; classic in 3; lupoid in 1 and unknown in 6 patients. Serum leishmanial antibody determination by IFAT performed on 12 cases were positive. Toxoplasma serology was negative. Histological picture of one lymph node biopsy showed an (anergic) intact histiocytic response characterized by thousands of intracellular amastigotes, no @entity39 and inconspicuous plasma cells. In 17 biopsies the picture was that of histiocytic granulomata with varying degrees of @entity39 , moderate numbers of amastigotes in several foci, @entity82 and varying numbers of plasma cells. One biopsy from a lupoid case shows numerous epitheloid granulomata, no organisms, no @entity39 and inconspicuous plasma cells. Electron microscopy has been performed on 8 biopsies to confirm leishmania amastigotes. Differential diagnosis from @entity3252 and @entity11102 is discussed. Histological types of responses in the lymph nodes are comparable to those described in @entity4536 : an anergic response with intact macrophage @entity738 , a histiocytic response with @entity39 , and a lupoid type of response with epithelioid @entity738 .

"Localized" leishmania XXXX : a light and electron microscopic study.

@entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity738 :: ('MESH:D006099', 'Disease') :: ['granulomas', 'granuloma'] @entity39 :: ('MESH:D009336', 'Disease') :: ['necrosis'] @entity234 :: ('MESH:D007898', 'Disease') :: ['visceral leishmaniasis'] @entity4536 :: ('MESH:D016773', 'Disease') :: ['cutaneous leishmaniasis', 'Cutaneous leishmaniasis'] @entity11102 :: ('MESH:D002372', 'Disease') :: ['cat-scratch disease'] @entity3252 :: ('MESH:D014123', 'Disease') :: ['toxoplasmosis'] @entity3298 :: ('MESH:D008199', 'Disease') :: ['lymphadenitis']
@entity3298 :: (MESH:D008199,Disease) :: ['lymphadenitis']
