@entity715 is a common pathology underlying @entity741 , @entity1211 ( @entity1211 ). The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2010 documented that @entity741 and @entity64 collectively caused one in four @entity204 worldwide. GBD  2010 did not report data for @entity1211 as a cause of @entity204 and disability. We performed a systematic review of the literature on the global disease burden caused by @entity1211 in @entity258 and high-income countries. Studies from western Europe, North America, Australia and southern Latin America (Argentina) yielded consistent results, with annual incidence rates ranging from 0.75 to 2.69 per 1000 individuals in the population. The incidence increased to between 2 and 7 per 1000 among those aged >=   70  years. Although the incidence is lower in individuals of Chinese and Korean ethnicity, their disease burden is not low, because of population aging. @entity1211 associated with hospitalization was the leading cause of disability-adjusted life-years (DALYs) lost in @entity258 and middle-income countries, and the second most common cause in high-income countries, being responsible for more DALYs lost than @entity55 , @entity1212 , and adverse drug events. @entity1211 causes a major @entity258 and high-income countries. More detailed data on the global burden of @entity1211 should be obtained to inform policy and resource allocation in health systems, and to evaluate whether improved utilization of preventive measures will reduce the burden.

XXXX : a major contributor to the global disease burden.

@entity1212 :: ('MESH:D055499', 'Disease') :: ['catheter-related bloodstream infections'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity55 :: ('MESH:D011014', 'Disease') :: ['nosocomial pneumonia'] @entity258 :: ('MESH:D009800', 'Disease') :: ['burden of disease across low-income, middle-income', 'low-income', 'low-income, middle-income'] @entity741 :: ('MESH:D017202', 'Disease') :: ['ischemic heart disease'] @entity715 :: ('MESH:D013927', 'Disease') :: ['Thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['ischemic stroke, and venous thromboembolism', 'VTE'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'deaths']
@entity715 :: (MESH:D013927,Disease) :: ['Thrombosis']
