OBJECTIVES: The aim of this retrospective study was to determine the predictors of @entity256 (ISR) among the lesions causing the first ISR by intravascular ultrasound (IVUS) studies. BACKGROUND: Although some predictors of diffuse ISR have been reported, parameters on IVUS relating to diffuse ISR are not well characterized. METHODS: We classified 52 ISR lesions that had undergone successful stent implantation and led to restenosis into two types--focal and diffuse ISR--using quantitative coronary angiography. @entity256 was defined as > or =50% diameter stenosis, and diffuse ISR as lesion length > or =10 mm at follow-up. The @entity5707 ( @entity5707 ) was defined as the vessel area at the @entity75 divided by that of averaged reference segments. RESULTS: There were no significant differences in @entity1 , angiographic, and procedural characteristics between the focal (n = 25) and diffuse (n = 27) ISR groups. Baseline @entity5707 was significantly greater in the diffuse ISR group (1.03 +/- 0.18 vs. 0.88 +/- 0.24, p = 0.0159). Negative remodeling, defined as @entity5707 <0.9, was detected in 60% of the focal ISR group and in only 26% of the diffuse ISR group. By logistic regression analysis, baseline @entity5707 was the only independent predictor of diffuse ISR (p = 0.0341). Moreover, volumetric analyses revealed that lesions developing into diffuse ISR had less capacity to compensate for further plaque growth. CONCLUSIONS: Among the first ISR lesions, baseline positive remodeling was the most powerful predictor of diffuse ISR. Measuring pre-interventional arterial remodeling patterns by IVUS may be helpful to stratify lesions at higher risk.

Arterial remodeling patterns before intervention predict XXXX : an intravascular ultrasound study.

@entity75 :: ('MESH:D001927', 'Disease') :: ['target lesion'] @entity1 :: ('9606', 'Species') :: ['patient'] @entity256 :: ('MESH:D023903', 'Disease') :: ['Restenosis', 'diffuse in-stent restenosis'] @entity5707 :: ('MESH:D020257', 'Disease') :: ['RI', 'remodeling index']
@entity256 :: (MESH:D023903,Disease) :: ['diffuse in-stent restenosis']
