We compared the efficacy of @entity3974 , @entity3303 , @entity1340 , and @entity3575 in minimizing @entity158 caused by the injection of @entity2898 in 250 @entity1 . After tourniquet application on the forearm, the @entity1 were given saline (3 mL) (Group 1, n = 50), @entity3974 (4 mg) (Group 2, n = 50), @entity3303 (30 mg) (Group 3, n = 50), @entity1340 (50 mg) (Group 4, n = 50), or @entity3575 (100 microg) (Group 5, n = 50) diluted into a 3-mL solution. The occlusion was released after 20 s and @entity2898 was injected over 10-15 s. The @entity1 were observed and asked immediately if they had @entity158 in the arm, and the response was assessed. Reactions such as discomfort and @entity158 , withdrawal of the hand, and so on after the administration of @entity2898 were recorded as side effects for 24 h. Ten @entity1 in Group 1, 28 @entity1 in Group 2, 37 @entity1 in Group 3, 30 @entity1 in Group 4, and 15 @entity1 in Group 5 reported no @entity158 . Light @entity158 was seen in 11 @entity1 in Group 1, 14 @entity1 in Group 2, 11 @entity1 in Group 3, 12 @entity1 in Group 4, and 20 @entity1 in Group 5. Moderate @entity158 was seen in 15 @entity1 in Group 1, 6 @entity1 in Group 2, 2 @entity1 in Group 3, 8 @entity1 in Group 4, and 10 @entity1 in Group 5. Severe @entity158 was seen in 14 @entity1 in Group 1, 2 @entity1 in Group 2, 0 @entity1 in Group 3, 0 @entity1 in Group 4, and 5 @entity1 in Group 5. Correlation determined with log-linear analysis found in Group 1 @entity158 score 0 (P < 0.001), Group 1 @entity158 score 1 (P < 0.001), and Group 3 @entity158 score 0 (P < 0.001). We conclude that @entity3974 , @entity3303 , @entity1340 , and @entity3575 decrease the level of @entity2898 injection @entity158 . Among these drugs, @entity3303 is the most effective, whereas @entity3575 is the least effective. IMPLICATIONS: We compared the efficacy of @entity3974 , @entity3303 , @entity1340 , and @entity3575 in minimizing the @entity158 on injection of @entity2898 in 250 @entity1 . @entity3974 , @entity3303 , @entity1340 , and @entity3575 were effective in preventing and decreasing the level of @entity2898 injection @entity158 . Among these drugs, @entity3303 was the most effective, and @entity3575 was the least effective.

The prevention of @entity158 from injection of @entity2898 by @entity3974 , @entity3303 , @entity1340 , and XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1340 :: ('MESH:D014147', 'Chemical') :: ['tramadol'] @entity3974 :: ('MESH:D017294', 'Chemical') :: ['ondansetron', 'Ondansetron'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity2898 :: ('MESH:C061870', 'Chemical') :: ['rocuronium'] @entity3575 :: ('MESH:D005283', 'Chemical') :: ['fentanyl']
@entity3575 :: (MESH:D005283,Chemical) :: ['fentanyl']
