Sixteen @entity1 with @entity15 , 14 with remitting and 2 with progressive course, and their follow up for 4-16 (mean, 9 years) are reported. The disease manifested in eight @entity1 at the age of 1.5-9 years, while in the other eight at the age of 12-14 years. The cases were acute, but had a stronger inclination to remission than in adulthood. In addition to the "classical" symptoms known in adult, @entity15 , papilloedema and acute @entity428 were observed in nine @entity1 . Dehydrating treatment was life saving in these cases. @entity1319 occurred in two @entity1 , and two @entity1 had @entity410 , one of whom later developed chronic @entity302 . The CSF was pathological in all the cases. Oligoclonal gamma-globulin subfraction was found in three out of the five @entity1 tested. Three @entity1 died. Histological examination was carried out in two of them; it revealed severe perivenous demyelinisation due to @entity32 . @entity821 treatment occasionally with @entity500 reduced the duration of exacerbations, but could not prevent renewed ones and caused severe side-effects. @entity15 is a rare but not exceptional condition in @entity1 . The differences between cases in @entity1 and adults are age-dependent.

XXXX in childhood: long term katamnestic investigations.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity410 :: ('MESH:D012640', 'Disease') :: ['convulsions'] @entity821 :: ('MESH:D003348', 'Chemical') :: ['Cortisone'] @entity500 :: ('MESH:D001379', 'Chemical') :: ['azathioprine'] @entity428 :: ('MESH:D019586', 'Disease') :: ['increased intracranial pressure'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy'] @entity15 :: ('MESH:D009103', 'Disease') :: ['Multiple sclerosis', 'multiple sclerosis'] @entity1319 :: ('MESH:D015835', 'Disease') :: ['Opsoclonus']
@entity15 :: (MESH:D009103,Disease) :: ['Multiple sclerosis']
