PURPOSE: To review the outcome of single-stage posterior instrumentation for progressive tubercular thoracic and thoracolumbar @entity1513 in 45 @entity1 . METHODS: Records of 16 @entity1 and 29 @entity1 aged 20 to 59 (mean, 34.1) years who underwent single-stage posterior instrumentation for active thoracic (n=27) or thoracolumbar (n=18) @entity378 by a single surgeon and were followed up for a minimum of 5 years were reviewed. Neurological status was evaluated using the Frankel grading system. @entity158 was assessed using the visual analogue score (VAS). Disability status was assessed using the Oswestry Disability Index (ODI). Outcome was graded according to the Kim and Lee criteria. @entity1513 at presentation, preoperation (after one month of conservative therapy), immediate postoperation, and 5-year follow-up was measured on radiographs to determine the @entity1513 progression, @entity85 , @entity86 , and @entity85 . RESULTS: Respectively for 27 and 18 @entity1 with thoracic or thoracolumbar involvement, at 5 years the mean VAS score improved from 5.5 to 1.9 (p<0.001) and from 6.8 to 1.5 (p<0.001), whereas the mean ODI improved from 60.8 to 11.7 (p<0.001) and from 57.5 to 7.6 (p<0.001). The outcome was excellent in 17 and 11, good in 7 and 5, and fair in 3 and 2 @entity1 , respectively. The mean @entity1513 progression from presentation to preoperation was from 20.2   to 26.2   and from 10.3   to 14.1  , respectively, whereas the corresponding mean predicted @entity1513 progression was from 15.5   to 48.1   and from 13.8   to 50.4  . The respective mean @entity85 was -8.1   and -8.5  ; the respective mean @entity85 was 4.1   and 6.8  ; and the respective mean loss of correction at 5 years was 1.9 and 1.9. Two @entity1 had a dural tear, and 3 @entity1 had a transient @entity130 . Two @entity6 @entity1 had @entity2737 . One @entity1 had downward migration of one rod at 30 months but remained asymptomatic. CONCLUSION: Single-stage posterior instrumentation combined with continued chemotherapy for a minimum 12 months is a viable option for early progressive @entity1513 .

Single-stage posterior instrumentation for progressive tubercular thoracic and thoracolumbar XXXX .

@entity1 :: ('9606', 'Species') :: ['men', 'women', 'patients', 'patient'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity1513 :: ('MESH:D007738', 'Disease') :: ['thoracic and thoracolumbar tubercular kyphosis', 'Kyphosis', 'kyphosis'] @entity2737 :: ('MESH:D014946', 'Disease') :: ['superficial wound infection'] @entity86 :: ('MESH:D019106', 'Disease') :: ['postoperative loss of correction'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain'] @entity85 :: ('MESH:D009140', 'Disease') :: ['correction of deformity', 'residual deformity'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculosis'] @entity130 :: ('MESH:D014947', 'Disease') :: ['root injury']
@entity1513 :: (MESH:D007738,Disease) :: ['kyphosis']
