Understanding of the elastic pressure/volume (Pel/V) curve is still limited in health and disease. The aim of the present study was to elucidate the Pel/V curve and @entity17220 ( @entity17220 ) lung (EL) and chest wall (ECW) in healthy @entity1707 . Six young (20.8 kg) and seven adult (58.9 kg), anaesthetized, paralysed and ventilated @entity1707 were studied. Pel/V curves were recorded at zero end-expiratory pressure (ZEEP) and at positive end-expiratory pressure (PEEP) up to 40 cm @entity2507 with a computer controlled ventilator during an insufflation at a low, constant flow. Pel/V curves of the respiratory system showed a complex pattern in both young and adult @entity1707 . During the insufflation, @entity17220 decreased, increased, fell, and increased again. A second Pel/V curve recorded immediately after the first one showed lower elastance and only one early fall in @entity17220 . ECW fell over the initial segment and was then nearly stable. Difference between 1st and 2nd curves reflected changes in EL caused by recruitment during the 1st insufflation. At PEEP, such signs of collapse and recruitment were reduced. A strong tendency to @entity891 contributes to a complex pattern of elastic pressure/volume curves. At low volumes and distending pressures the chest wall contributes significantly to changes in respiratory system elastance.

Elastic properties of the lung and the chest wall in young and adult healthy XXXX .

@entity1707 :: ('9823', 'Species') :: ['pigs'] @entity2507 :: ('CHEBI:33813', 'Chemical') :: ['H2O'] @entity17220 :: ('MESH:D015619', 'Disease') :: ['elastance of the respiratory system', 'ERS'] @entity891 :: ('MESH:D001261', 'Disease') :: ['lung collapse']
@entity1707 :: (9823,Species) :: ['pigs']
