OBJECTIVE: This study provides prenatal characteristics and postnatal outcomes of @entity1 with severe @entity3799 . METHODS: A retrospective analysis of clinical information from cases prenatally diagnosed with severe @entity3799 (>90   angulation) in the Fetal Care Center at Cincinnati @entity1 's Hospital Medical Center between 2007 and 2010 was performed. We excluded @entity601 and @entity5 of the head or neck. RESULTS: We identified five @entity1 with severe @entity3799 . The fetal spine abnormality was diagnosed between 18 and 27 weeks of gestation. Classical cesarean section was recommended in all @entity1 . There were no immediate airway or neurological complications in the delivery room. @entity154 were present in four of the five @entity1 . These @entity1 had a more complicated clinical course and three separate syndromes including a complex collagenopathy, @entity4032 , and @entity11375 were identified. One @entity1 had an isolated cervical deformation secondary to a large uterine fibroid with a benign clinical course. None of the @entity1 have required spinal surgery. CONCLUSION: Our @entity1 suggest that connective tissue diseases or @entity4032 may be important risk factors for the development of severe @entity3799 . There were no significant long-term complications directly related to @entity3799 .

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@entity1 :: ('9606', 'Species') :: ['patients', 'Children', 'patient', 'infants'] @entity154 :: ('MESH:D000013', 'Disease') :: ['Extravertebral anomalies'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity11375 :: ('MESH:D007714', 'Disease') :: ['Klippel-Feil syndrome'] @entity3799 :: ('MESH:D002575', 'Disease') :: ['cervical scoliosis'] @entity601 :: ('MESH:D009436', 'Disease') :: ['iniencephaly'] @entity4032 :: ('MESH:D059446', 'Disease') :: ['heterotaxy']
@entity3799 :: (MESH:D002575,Disease) :: ['Severe cervical scoliosis']
