BACKGROUND: @entity1956 remains the most common transfusion-transmitted @entity1800 . We explored the current status of pre-transfusion screening and post-transfusion follow-up testing for @entity1956 virus (HBV) surface antigen (HBsAg) and antibodies (anti-HBs) in blood recipients from an area of high @entity97 endemicity. METHODS: A total of 7,780 blood recipients were transfused with at least 1 unit of blood component at a single university hospital in Korea between January 2006 and December 2009. Their medical records were reviewed, and their demographic and transfusion-related data were analyzed. RESULTS: Pre-transfusion HBsAg and anti-HBs levels were tested in 77.6% (6,037/7,780) of the recipients. The results varied widely according to recipient age. In all, 32.8% (1,982/6,037) of the recipients who were tested had dual negative pre-transfusion results for HBsAg and anti-HBs and, therefore, were at increased risk of @entity97 transmission. Post-transfusion follow-up testing for HBsAg and/or anti-HBs was performed in 22% (436/1,982) of the increased-risk group. CONCLUSIONS: Our data show that current transfusion-related laboratory testing practice is not sufficient to properly investigate possible post-transfusion infections. Routine laboratory tests, including HBsAg and anti-HBs, should be recommended in transfusion guidelines.

Pre- and post-transfusion testing for XXXX virus surface antigen and antibody in blood recipients: a single-institution experience in an area of high endemicity.

@entity97 :: ('10407', 'Species') :: ['HBV'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral infection'] @entity1956 :: ('MESH:D006509', 'Disease') :: ['Hepatitis B', 'hepatitis B']
@entity1956 :: (MESH:D006509,Disease) :: ['hepatitis B']
