BACKGROUND: Psoriasis is an immunoinflammatory disease associated with cardiovascular risk factors, atherothrombotic events, and @entity49 . @entity1211 ( @entity1211 ) is potentially lethal and shares risk factors with @entity1569 , but the risk of @entity1211 associated with @entity1569 is unknown. The present study investigated the potential association between @entity1569 and @entity1211 . METHODS AND FINDINGS: Information from nationwide prospectively recorded registers of hospitalization, drug dispensing from pharmacies, socio-economic data, and causes of @entity204 was linked on an individual level. In an unselected nationwide cohort, we used multivariate Poisson regression models controlling for age, gender, comorbidity, concomitant medication, socio-economic data, and calendar year, to assess the risk of @entity1211 associated with @entity1569 . A total of 35,138 @entity1 with mild and 3,526 @entity1 with severe @entity1569 were identified and compared with 4,126,075 controls. @entity1 with @entity1569 had higher incidence rates per 1000 @entity1 -years of @entity1211 than controls (1.29, 1.92, and 3.20 for controls, mild @entity1569 , and severe @entity1569 , respectively). The rate ratio (RR) of @entity1211 was elevated in all @entity1 with @entity1569 with RR 1.35 (95% confidence interval [CI] 1.21-1.49) and RR 2.06 (CI 1.63-2.61) for mild and severe @entity1569 , respectively. Exclusion of @entity1 with @entity5 , and censoring of @entity1 undergoing surgery did not alter the results. CONCLUSION: This nationwide cohort study indicates that @entity1 with @entity1569 are at increased risk of @entity1211 . The risk was highest in young @entity1 with severe @entity1569 . Physicians should be aware that @entity1 with @entity1569 may be at increased risk of both venous and arterial @entity1031 events.

Psoriasis carries an increased risk of XXXX : a Danish nationwide cohort study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'person'] @entity1569 :: ('MESH:D011565', 'Disease') :: ['psoriasis'] @entity5 :: ('MESH:D009369', 'Disease') :: ['malignancies'] @entity49 :: ('MESH:D019851', 'Disease') :: ['hypercoagulability'] @entity1031 :: ('MESH:D013923', 'Disease') :: ['thromboembolic'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['Venous thromboembolism', 'VTE'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity1211 :: (MESH:D054556,Disease) :: ['venous thromboembolism']
