OBJECTIVE: @entity393 is a possible complication of vestibular neurectomy and intratympanic @entity801 administration in M  ni  re's disease. The aim of this study was to compare the incidence of this complication with the two treatments. STUDY DESIGN: Retrospective review. SETTING: Tertiary referral center. @entity1 : The initial study population reviewed consisted of 24 @entity1 receiving @entity801 injections and 209 @entity1 undergoing vestibular nerve section. Comparison of data was performed among all 24 intratympanic @entity801 @entity1 and the last 24 vestibular neurectomy @entity1 operated on via the retrosigmoid approach. INTERVENTIONS: Intratympanic @entity801 administration (26-156 mg) and @entity394 . MAIN OUTCOME MEASURE: Auditory and vertigo results were evaluated according to the American Academy of Otolaryngology 1995 criteria. RESULTS: The mean preoperative pure-tone average for @entity1 undergoing vestibular nerve section was 48.5 dB, with a speech discrimination score of 85%. In these @entity1 , the postoperative pure-tone average was 50.3 dB, and the speech discrimination score was 82%. @entity1 undergoing @entity801 injection had a mean pretreatment pure-tone average of 50.1 dB and a speech discrimination score of 87%. The posttreatment pure-tone average and discrimination score for the @entity801 group were 74.7 dB and 65%, respectively. The amount of postprocedure @entity393 was significantly greater in the @entity801 group (p = 0.03). Excellent control of vertigo (classes A and B) was obtained in 95.8% of the @entity1 treated with vestibular nerve section and in 75% of the @entity1 in the @entity801 group. CONCLUSION: @entity801 administration and vestibular neurectomy are both effective for relieving vertigo in M  ni  re's disease. The incidence of @entity393 is significantly higher after @entity801 injection.

Auditory results after vestibular nerve section and intratympanic XXXX for M  ni  re's disease.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity801 :: ('MESH:D005839', 'Chemical') :: ['gentamicin', 'Gentamicin'] @entity393 :: ('MESH:D034381', 'Disease') :: ['hearing loss', 'Hearing loss'] @entity394 :: ('MESH:D015837', 'Disease') :: ['retrosigmoid vestibular neurectomy']
@entity801 :: (MESH:D005839,Chemical) :: ['gentamicin']
