BACKGROUND: A majority of factors associated with the occurrence of clinical relevant postoperative @entity3472 (CR-POPF) after pancreaticoduodenectomy (PD) can only be identified intra- or postoperatively. There are no reports for assessing the morphological features of @entity788 and analyzing its influence on CR-POPF risk after PD preoperatively. METHOD: A total of 90 @entity1 underwent PD between April 2012 and May 2014 in our hospital were included. Preoperative computed tomographic (CT) images were imported into the Medical Image Three-Dimensional Visualization System (MI-3 @entity6094 ) for acquiring the morphological features of @entity788 . The demographics, laboratory test and morphological features of @entity788 were recorded prospectively. The clinical course was evaluated focusing on the occurrence of @entity3472 as defined by the International Study Group on @entity3472 (ISGPF). Logistic regression analysis was used to identify independent predictors of CR-POPF. RESULTS: CR-POPF occurred in 18 @entity1 (14 grade B, 4 grade C). In univariate analysis, male gender (P  =  0.026), body mass index (BMI)  >=   25.3  kg/m(2) (P  =  0.002), main pancreas duct diameter (MPDD)  <  3.1  mm (P  =  0.005), remnant pancreatic parenchymal volume (RPPV)  >  27.8  mL (P  <  0.001), and area of cut surface (AOCS)  >  222.3  mm(2) (P  <  0.001) were associated with an increased risk of CR-POPF. In multivariate analysis, BMI  >=   25.3  kg/m(2) (OR 12.238, 95  % CI 1.822-82.215, P  =  0.010) and RPPV  >  27.8  mL (OR 12.907, 95  % CI 1.602-104.004, P  =  0.016) were the only independent risk factors associated with CR-POPF. A cut-off value of 27.8  mL for RPPV established based on the receiver operating characteristic (ROC) curve, which was the strongest single predictive factor for CR-POPF, with a sensitivity and specificity of 77.8 and 86.1  %, respectively. The area under the ROC curve of RPPV was 0.770 (95  % CI 0.629-0.911, P  <  0.001). CONCLUSIONS: Our study demonstrated that CR-POPF is correlated with BMI and RRPV. MI-3 @entity6094 provides us a novel and convenient method for measuring the RPPV. Preoperative acquisition of RPPV and BMI may help the surgeons in fitting postoperative management to @entity1 's individual risk after PD.

Body Mass Index and Stump Morphology Predict an Increased Incidence of XXXX After Pancreaticoduodenectomy.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity788 :: ('MESH:D010190', 'Disease') :: ['pancreatic stump'] @entity3472 :: ('MESH:D010185', 'Disease') :: ['Pancreatic Fistula', 'pancreatic fistula'] @entity6094 :: ('216614', 'Species') :: ['DVS']
@entity3472 :: (MESH:D010185,Disease) :: ['Pancreatic Fistula']
