UNASSIGNED: 878 Background: Less than 5% of new @entity5 @entity1 participate in clinical trials. The objective of this study was to evaluate accrual to a clinical trial of @entity0 adjuvant chemotherapy at a regional @entity5 centre. METHODS: A retrospective review of @entity1 treated for primary @entity0 between June 2001 and June 2003 was conducted. RESULTS: 165 charts were reviewed. 62 @entity1 received adjuvant chemotherapy. Of these, 42 (68%) fit the age criteria for the clinical trial. 15 were ineligible due to @entity5 characteristics. Of the 27 @entity1 who were eligible for the trial based on age and @entity5 characteristics, 12 (44%) could not be treated on clinical trial because they lived in a peripheral community. Of the 15 remaining @entity1 who were eligible for treatment on clinical trial at the @entity5 center, 7 (47%) were actually entered in the trial. @entity1 's fear of potential @entity137 was the primary reason for not participating in the clinical trial. CONCLUSIONS: At our institution, living in a peripheral community was a leading reason for ineligibilty for a clinical trial of adjuvant chemotherapy of @entity0 . Accrual to this specific trial was nearly half of all @entity1 who were eligible based on age, @entity5 characteristics, and location. No significant financial relationships to disclose.

Local accrual pattern of a XXXX adjuvant chemotherapy clinical trial.

@entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
