BACKGROUND/AIMS: Liver transplantation for @entity3851 remains controversial at many transplant centers. The aim of the present study was to evaluate the outcome of @entity1 with @entity5881 who underwent liver transplantation at Centro Trapianti, Policlinico S. Orsola, Bologna. METHODOLOGY: We describe the outcomes of 18 @entity988 @entity1 with @entity3851 who received orthotopic liver transplants at our center from April, 1986 to February, 1996. The data obtained was compared with that of 114 @entity1 with virus-related @entity82 selected as transplant controls. An absolute period of abstinence from @entity167 consumption for at least six months was required. RESULTS: Regarding the actuarial survival rate and @entity455 , no significant differences were noted in comparing the non- @entity988 with the @entity988 recipients, except for a higher incidence of @entity2803 in the @entity988 group followed-up for more than four months. The @entity988 relapse rate was 27.2%, but only one @entity1 returned to harmful drinking. Seventy-three percent of subjects who were followed-up for at least six months were occupied in gainful employment. @entity988 did not affect employment status. CONCLUSION: This data demonstrates that liver transplantation for selected @entity1 with end-stage alcohol-related @entity82 achieves good results in survival, complications and employment status, and it appears difficult to defend an inflexible claim to have demonstrated an absolute long-term abstinence before transplantation when a severe deterioration of liver function is present.

Orthotopic liver transplantation for XXXX : rates of survival, complications and relapse.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2803 :: ('MESH:D003586', 'Disease') :: ['Cytomegalovirus infection'] @entity82 :: ('MESH:D005355', 'Disease') :: ['cirrhosis'] @entity5881 :: ('MESH:D008108', 'Disease') :: ['alcoholic liver disease'] @entity455 :: ('MESH:D014652', 'Disease') :: ['non-fatal post-transplant complications'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity988 :: ('MESH:D000437', 'Disease') :: ['Alcoholic relapse', 'alcoholic'] @entity3851 :: ('MESH:D058625', 'Disease') :: ['end-stage liver disease', 'alcoholic end-stage liver disease']
@entity5881 :: (MESH:D008108,Disease) :: ['alcoholic liver disease']
