BACKGROUND: @entity1162 ( @entity1162 ) can lead to @entity943 , especially @entity1166 ( @entity1166 ) @entity591 and/or @entity1165 ( @entity1165 ). The aim of this study is to characterize @entity1 with life-threatening @entity943 associated with drug-induced @entity1162 and to identify risk factors of distinct presenting @entity943 . MATERIAL AND METHODS: In this retrospective study, we present 33 consecutive cases of life-threatening @entity943 associated with drug-induced long QT, which were direct admitted as emergency to a medical intensive care unit (MICU) during an observational time of 6 years. RESULTS: Of 33 identified cases, 55   % presented with @entity1166 with the need of resuscitation and 45   % showed nonsustained @entity1165 , respectively. In the total cohort the mean corrected QT interval (QTc) was 532        29  ms, with 530        31  ms (n   =   14) in @entity1 and 533        28  ms (n   =   19) in @entity1 (p   =   0.80), respectively. Cardiac drugs with QTc interval prolonging effect were reported in 24   % of cases, and the other 76   % involved noncardiac medications. Although @entity1371 is the most common risk factor for drug-induced malignant @entity943 , a QTc interval of at least 500  ms seems to be the major determinant of the risk of drug-induced proarrhythmias. Interestingly, @entity1 with @entity1166 exhibit more @entity1168 as such with @entity1165 . CONCLUSIONS: This is the first study of @entity1 with drug-induced life-threatening @entity943 who were admitted as a case of emergency to a MICU. Physicians should be aware of drug-induced @entity1162 and be able to identify @entity1 at risk and avoid specific drugs in such @entity1 .

Life-threatening XXXX due to drug-induced @entity1162 : A retrospective study over 6 years from a medical intensive care unit.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['VT', 'ventricular tachycardia'] @entity1166 :: ('MESH:D016171', 'Disease') :: ['TdP', 'torsade de pointes'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['bradycardia'] @entity591 :: ('MESH:D013610', 'Disease') :: ['tachycardia'] @entity1162 :: ('MESH:D008133', 'Disease') :: ['LQTS', 'Long QT syndrome'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmia', 'cardiac arrhythmias', 'arrhythmias'] @entity1371 :: ('MESH:D007008', 'Disease') :: ['hypokalemia']
@entity943 :: (MESH:D001145,Disease) :: ['cardiac arrhythmias']
