BACKGROUND: Data relating high-sensitivity cardiac troponin T (hs- @entity10020 ) to long-term myocardial function and @entity1188 size in @entity1 after @entity583 ( @entity583 ) are lacking. We aimed to evaluate the use of early hs- @entity10020 concentrations for prediction of myocardial function and @entity1188 size assessed by cardiac magnetic resonance imaging (CMR) one year following @entity583 . METHODS: Sixty-six @entity1 , revascularized by primary percutaneous coronary intervention (PCI) for first-time @entity583 , were enrolled in this observational study. Serial hs- @entity10020 , @entity908 kinase (CK), high-sensitivity C-reactive protein (hs-CRP) and @entity880 dehydrogenase (LDH) levels were measured on admission, 6h, 12h, and 24h post-PCI. @entity1 underwent CMR within the first week and 12months thereafter. RESULTS: Except for admission hs- @entity10020 , all single time point and peak hs- @entity10020 concentrations showed significant correlations with left ventricular ejection fraction (LVEF: r=-0.404 to -0.517, all ps<0.01) and @entity1188 size (IS: r=0.421 to 0.700, all ps<0.01) at baseline and follow-up. The area under the curve (AUC) of peak hs- @entity10020 was 0.82 (95% CI 0.71-0.92) for the prediction of decreased LVEF (<55%) and 0.89 (95% CI 0.81-0.97) for the prediction of large IS (>8%) at 12months. The combination of all four biomarkers resulted in an AUC of 0.82 and 0.92 for the prediction of reduced LVEF and large IS at 12months, respectively (both ps>0.05). CONCLUSION: In stable @entity583 @entity1 successfully revascularized by primary PCI, serial and peak concentrations of hs- @entity10020 are closely correlated to long-term LVEF and IS. Combination of hs- @entity10020 with CK, hs-CRP, or LDH did not add any significant prognostic value as compared with hs- @entity10020 alone.

High-sensitivity troponin T for prediction of left ventricular function and XXXX size one year following @entity583 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity908 :: ('MESH:D003401', 'Chemical') :: ['creatine'] @entity10020 :: ('7139', 'Gene') :: ['cTnT'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct'] @entity880 :: ('MESH:D019344', 'Chemical') :: ['lactate'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST-elevation myocardial infarction']
@entity1188 :: (MESH:D007238,Disease) :: ['infarct']
