BACKGROUND: The objective of this study was to investigate @entity65 risk factor (cvRF) profiles and compare their trends over 17 years in @entity1 with and without @entity1187 ( @entity1187 ) undergoing percutaneous coronary intervention (PCI). HYPOTHESIS: Time trends of cvRF are different between @entity1187 and non- @entity1187 @entity1 . METHODS: This study was a time-trend analysis from 1994 to 2010 within the Mayo Clinic PCI registry. Outcome measures were incidence and prevalence of cvRF, including the Framingham Risk Score (FRS), at the time of admission for PCI. RESULTS: Age of non- @entity1187 @entity1 was higher than that of @entity1187 @entity1 , and age distribution slightly shifted toward older age in both groups (P for trend <0.001). There was no difference in FRS between the 2 groups; however, 10-year @entity65 risk (%) remained higher in non- @entity1187 than in @entity1187 @entity1 , decreasing over time. Diastolic blood pressure and high-density lipoprotein @entity165 were higher in non- @entity1187 @entity1 , but total @entity165 and low-density lipoprotein @entity165 were higher in @entity1187 @entity1 , with an improving trend over time. Prevalence of @entity6 , @entity101 , and history of @entity1007 were higher in non- @entity1187 @entity1 , increasing over time. Smoking did not change over time. Use of most medications increased over time in both groups. CONCLUSIONS: Most cvRFs and their time trends exhibited statistically significant differences between @entity1187 and non- @entity1187 @entity1 , except systolic blood pressure, body mass index, and history of @entity583 . A new risk-factor profile assessment may be needed for stratification of PCI @entity1 according to @entity1187 and non- @entity1187 status. Clinical and public-health interventions should consider different approaches to @entity1187 and non- @entity1187 @entity1 .

Comparison of Time Trends of XXXX Risk Factors and Framingham Risk Score Between @entity1 With and Without Acute Coronary Syndrome Undergoing Percutaneous Intervention Over the Last 17 Years: From the Mayo Clinic Percutaneous Coronary Intervention Registry.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndrome'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity1007 :: ('MESH:D006937', 'Disease') :: ['hypercholesterolemia'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity65 :: (MESH:D002318,Disease) :: ['Cardiovascular Disease']
