OBJECTIVE: There is a possible correlation between @entity46 and an increased risk of @entity43 ( @entity43 ), but many uncertainties remain, including race, exposure or surveillance time, and surgical confirmation. Therefore, we carried out a large-scale, nationwide, controlled cohort study in the Taiwanese @entity1 to respond to these uncertainties. MATERIALS AND METHODS: A historical cohort study was performed by linking the National Health Insurance Research Database of Taiwan. Each @entity1 diagnosed with @entity46 (n  =  7537) between 2000 and 2009 was background matched with up to two @entity1 without @entity46 (n  =  15,074). The total was 136,643 @entity1 -years of follow-up and 24 @entity1 having new @entity43 . Cox regression analysis was used to determine the relationship between the @entity43 incidence rate and an @entity46 status. RESULTS: The @entity43 incidence rate of the @entity46 and @entity46 @entity1 was 3.31 per 10,000 @entity1 -years and 0.99 per 10,000 @entity1 -years, respectively, contributing to an adjusted hazard ratio (HR) of 3.28 (95% confidence interval, 1.37-7.85). The @entity1 with surgical confirmation had a much higher adjusted HR (3.87; 95% confidence interval, 1.58-9.47). No significantly statistical difference of surveillance time between @entity1 with and without @entity46 (3.87  years vs. 3.73  years). The occurrence of @entity43 was not also affected by exposure time of @entity1 with @entity46 . CONCLUSION: Taiwanese @entity1 with @entity46 really had a risk of newly developed @entity43 , especially those who had a surgical diagnosis, and this three-fold increase of risk was neither influenced by exposure time nor biased by surveillance.

Endometriosis and the subsequent risk of XXXX .

@entity43 :: ('MESH:D010051', 'Disease') :: ['EOC', 'epithelial ovarian cancer'] @entity1 :: ('9606', 'Species') :: ['women', 'patient', 'person'] @entity46 :: ('MESH:D004715', 'Disease') :: ['non-endometriosis', 'endometriosis']
@entity43 :: (MESH:D010051,Disease) :: ['epithelial ovarian cancer']
