BACKGROUND: In Africa, studies primarily devoted to @entity6008 due to @entity3458 are rare. The objectives of the study were to determine the epidemiology, diagnosis and progression of @entity6008 in @entity3458 . @entity1 AND METHODS: A 5-year multicentre, retrospective study was conducted in three university hospitals in Dakar. We included all @entity1 with @entity6008 occurring in a setting of @entity3458 . RESULTS: We identified 40  cases of @entity6008 associated with @entity3458 , representing 3.4% of the current population of sickle cell @entity1 in our institutions. The average @entity1 age was 25.9  years and the sex ratio was 2.33. @entity6008 was the presenting feature enabling diagnosis of @entity3458 in one third of the cases. The average time to consultation from onset was 5.4  years. @entity158 was reported in 22  cases (48%). @entity1066 were isolated in 76% and multiple in 24% of cases. The most common site was the medial malleolus (39%). A CBC allowed identification of @entity417 in 35  cases. Haemoglobin electrophoresis was performed and homozygous sickle cell SS disease was identified in 39  cases and heterozygous @entity13654 in 1  case. Local treatments included physiologic serum, topical antibiotics and skin grafting. Systemic treatment included supplementation with @entity1501 in all @entity1 , blood transfusion in 16  cases, vasodilators in 11  cases and antibiotics in 25  cases. The outcome was favourable in 61.8% of cases. DISCUSSION: In Dakar, @entity3458 is a common cause of @entity6008 and is frequently revealed by @entity6008 .

[Leg ulcers in XXXX : A retrospective study of 40  cases].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity1501 :: ('MESH:D005492', 'Chemical') :: ['folic acid'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anaemia'] @entity13654 :: ('MESH:D006450', 'Disease') :: ['SC disease'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['Ulcers'] @entity3458 :: ('MESH:D000755', 'Disease') :: ['sickle cell disease'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain'] @entity6008 :: ('MESH:D007871', 'Disease') :: ['chronic leg ulcers', 'chronic leg ulcer', 'Chronic leg ulcer']
@entity3458 :: (MESH:D000755,Disease) :: ['sickle cell disease']
