BACKGROUND: The relation between diet and @entity1 health has long been investigated. The aim of this work is to evaluate the association between CHD risk and the consumption of fruit and vegetable, in a large sample of cardiac @entity1 and controls. METHODS: Stratified sampling from all Greek regions, consisted of 848 (700 males, 58 +/- 10 years old and 148 females, 65 +/- 9 years old) randomly selected @entity1 , admitted to the cardiology clinic for a first event of an @entity1187 ( @entity1187 ). In addition we selected 1078 frequency paired, by sex-age-region, controls in the same hospitals but without any clinical suspicion of CHD. Using validated food-frequency questionnaires we assessed total diet, including fruit and vegetable intake, on a weekly basis. Multiple logistic regression analysis estimated the relative risk of developing @entity1187 by level of fruits and vegetables intake after taking into account the effect of several potential confounders. RESULTS: Data analysis revealed that the benefit of fruit or vegetable consumption increases proportionally by the number of servings consumed (P for trend < 0.001). After adjusting for the conventional cardiovascular risk factors, those in the upper quintile of fruit consumption (5 or more items/day) had 72% lower risk for CHD (odds ratio = 0.28, 95% CI 0.11-0.54, P < 0.001), compared with those in the lowest quintile of intake (< 1 items/day). Similarly, consumption of vegetable more than 3 days/week was associated with 70% lower risk for CHD (odds ratio = 0.30, 95% CI 0.22-0.40, P < 0.001), compared with those that they did not consume vegetables. Of particular interest, a 10% reduction in coronary risk was observed for every one piece of fruit consumed per day (odds ratio = 0.90, 95% CI 0.85-0.97, P = 0.004). CONCLUSIONS: Consumption of fruits and vegetables seems to offer significant protection against CHD.

Consumption of fruits and vegetables in relation to the risk of developing XXXX ; the CARDIO2000 case-control study.

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['acute coronary syndrome', 'ACS']
@entity1187 :: (MESH:D054058,Disease) :: ['acute coronary syndromes']
