BACKGROUND _ OBJECTIVES: @entity1 frequently experience @entity158 of moderate to severe degree during gynaecologic procedures. This prospective, randomized, placebo-controlled trial was aimed to investigate the analgesic efficacy of preoperative oral @entity20365 , intravenous @entity1443 , @entity3303 spray, @entity6882 and @entity3522 on fractional curettage procedure. METHODS: A total of 144 mutiparous @entity1 were randomly allocated to one of the six groups. The first group (control group) consisted of 22 @entity1 and they did not receive any treatment. The second group had 26 @entity1 receiving oral 25 mg @entity20365 . The 23 @entity1 of the third group received two puff @entity3303 sprays on cervical mucosa. t0 he forth group consisted of 25 @entity1 receiving 100 mg @entity6882 . In the fifth group, the 23 @entity1 received 1000 mg intravenous @entity1443 and the sixth group consisted of 25 @entity1 receiving @entity3522 . RESULTS: @entity6882 was the best choice for reducing @entity158 score during curettage procedure (t2:intra-operative). All analgesic procedures were significantly effective in reducing @entity158 during postoperative period (t3). Significant @entity158 reduction was achieved for both intra- and postoperative period by using analgesics. INTERPRETATION _ CONCLUSIONS: The results of our study showed that @entity3303 puffs provided the @entity158 relief than the other analgesics used. Therefore, @entity3303 may be considered as the first choice analgesic in fractional curettage (NCT ID: 01993589).

Effect of @entity1443 , @entity20365 , @entity3303 spray, XXXX _ @entity3522 application for @entity158 relief during fractional curettage: A randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Patients'] @entity3522 :: ('MESH:D004008', 'Chemical') :: ['diclofenac sodium'] @entity6882 :: ('MESH:D008614', 'Chemical') :: ['Pethidine', 'pethidine'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain', 'best pain'] @entity1443 :: ('MESH:D000082', 'Chemical') :: ['paracetamol'] @entity20365 :: ('MESH:C118296', 'Chemical') :: ['dexketoprofen trometamol']
@entity6882 :: (MESH:D008614,Chemical) :: ['pethidine']
