BACKGROUND AND OBJECTIVES: Partial nephrectomy or radical nephrectomy is the standard of care for @entity1 with @entity703 , but surgery may result in @entity177 . We sought to identify @entity1 characteristics associated with renal functional recovery following radical nephrectomy. DESIGN, SETTING, @entity1 , _ MEASUREMENTS: We performed a retrospective study among 572 @entity1 with @entity703 who underwent RN between 2006 and 2013. The primary endpoint was recovery of postoperative @entity470 to the preoperative level. We plotted the trajectory of each @entity1 's @entity470 from their first postoperative visit up to 3 years after surgery. Cumulative incidence and competing risks regression estimated associations between @entity1 and clinical characteristics and @entity470 recovery, stratified by preoperative @entity470 . RESULTS: Median age was 61.5 years; 68% of @entity1 were male, and 89% were white. Overall, @entity470 increased over time following an @entity86 . Median postoperative follow-up among survivors was 10.8 (minimum, 0.03; maximum, 36.0) months; during follow-up, 263 @entity1 achieved @entity470 recovery. Median time to @entity470 recovery was 25.3 months. Two-year cumulative incidence of @entity470 recovery was 49% overall and 44% and 58% among those with preoperative @entity470 >= 60 and <60 ml/min per 1.73 m(2), respectively (P<0.001). On multivariable analysis, younger age at surgery and female sex were significantly associated with a higher chance of @entity470 recovery among @entity1 with preoperative @entity470 <60 ml/min per 1.73 m(2). Among @entity1 with preoperative @entity470 >= 60 ml/min per 1.73 m(2), @entity101 was significantly associated with a lower chance of @entity470 recovery, whereas @entity5 size was significantly associated with a higher chance of @entity470 recovery. CONCLUSIONS: Overall, almost half of the @entity1 in this study recovered to their preoperative @entity470 by 2 years following surgery. Distributions of preoperative risk factors differed by preoperative @entity470 , leading to distinct factors that were significantly associated with chance of @entity470 recovery.

Factors Associated with Recovery of Renal Function following Radical XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PARTICIPANTS'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity470 :: ('1956', 'Gene') :: ['eGFR'] @entity5 :: ('MESH:D009369', 'Disease') :: ['increased tumor'] @entity177 :: ('MESH:D051437', 'Disease') :: ['loss of renal function'] @entity86 :: ('MESH:D019106', 'Disease') :: ['initial postoperative decrease'] @entity703 :: ('MESH:D007680', 'Disease') :: ['kidney neoplasms']
@entity703 :: (MESH:D007680,Disease) :: ['Nephrectomy for Kidney Neoplasms']
