OBJECTIVE: To study the relationship between intrauterine growth and the @entity209 , particularly fasting serum lipids in young adulthood. METHODS: Seven hundred and forty-four young adults aged 26-31 years participated in the ARYA birth cohort. Birth characteristics were available from charts kept by the Municipal Health Service, Utrecht, The Netherlands. Adult medical history and lifestyle information were assessed by questionnaires. Adult anthropometry, blood pressure, fasting plasma @entity413 , total @entity165 , HDL- @entity165 , @entity1674 were measured, and LDL- @entity165 was calculated. RESULTS: Subjects in the lower tertiles of birth weight (1250-3209 and 3210-3649 g) had higher risks for @entity209 than those in the highest birth weight tertile (3650-5500 g): odds ratio, 1.8; 95% confidence interval (CI) 1.0-3.5 and 1.4; 0.7-2.7, respectively; p for trend = 0.064, adjusted for gender, @entity65 family history and current education. Birth weight was inversely related to @entity551 (linear regression coefficient, -1.9 mmHg/kg birth weight; 95% CI -3.4 to -0.3) and to (log) @entity1674 in mmol/L (-0.03/kg birth weight; 95% CI -0.06 to -0.01), adjusted for gender, current body mass index and current education. Birth weight showed inverse relations to diastolic blood pressure, serum @entity413 , total and LDL @entity165 and positive relations to waist circumference and HDL @entity165 levels, although not statistically significant. Birth length and ponderal index were not related to the @entity209 or lipid profiles. CONCLUSION: Lower birth weight indicates a higher risk for @entity209 in young adults, particularly through higher serum @entity1674 and higher @entity551 .

Lower birth weight predicts XXXX in young adults: the Atherosclerosis Risk in Young Adults (ARYA)-study.

@entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity209 :: ('MESH:D008659', 'Disease') :: ['metabolic syndrome'] @entity551 :: ('MESH:D007022', 'Disease') :: ['systolic blood pressure'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity209 :: (MESH:D008659,Disease) :: ['metabolic syndrome']
