This series describes the sonographic characteristics and pregnancy outcomes of fetuses with abnormal insertion of the umbilical vein (UV) into the inferior vena cava (IVC). We conducted a retrospective study that described the sonographic features of 6 @entity1 who underwent a routine anatomic scan during early pregnancy. Six @entity1 had a diagnosis of abnormal insertion of the UV to the IVC; in 3, the diagnosis was made at 12 weeks' gestation. @entity299 were detected in 3 @entity1 , including @entity1757 , @entity2294 , tricuspid and @entity339 , and an @entity5216 . Four had @entity154 , including @entity75 . Only 1 fetus who presented with UV insertion into the IVC as an isolated finding had a normal karyotype, resulting in term vaginal delivery. Four other @entity1 had @entity2008 , including trisomies 13 and 21, Turner mosaicism of 45,XO/46,XY, and Robertsonian translocation, and 1 @entity1 terminated the pregnancy without a karyotype evaluation. Abnormal insertion of the UV into the IVC with agenesis of the ductus venosus can be seen as early as the first trimester. When detected, a detailed anatomic examination should be performed, as well as a fetal karyotype evaluation. Isolated cases of insertion of the UV into the IVC at a position lower than usual may have a good prognosis.

Umbilical vein insertion into the inferior vena cava: an ominous sign of XXXX ?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity154 :: ('MESH:D000013', 'Disease') :: ['noncardiac anomalies'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral regurgitation'] @entity2294 :: ('MESH:D010490', 'Disease') :: ['pericardial effusion'] @entity75 :: ('MESH:D001927', 'Disease') :: ['cystic hygroma and skeletal, brain, and abdominal anomalies'] @entity1757 :: ('MESH:D006345', 'Disease') :: ['ventricular septal defects'] @entity299 :: ('MESH:D006331', 'Disease') :: ['Cardiac anomalies'] @entity2008 :: ('MESH:D002869', 'Disease') :: ['chromosomal abnormalities'] @entity5216 :: ('MESH:C535555', 'Disease') :: ['aberrant right subclavian artery']
@entity2008 :: (MESH:D002869,Disease) :: ['chromosomal abnormalities']
