OBJECTIVES/HYPOTHESIS: The goal of the study was to identify geographic trends in the primary treatment of @entity5 . STUDY DESIGN: Retrospective analysis of the United States National @entity5 Institute's Surveillance, Epidemiology, and End-Results (SEER) database. METHODS: Using the most up-to-date November 2014 submission of the SEER database in addition to SEER-18 data files, a cohort was created of stage I to II squamous cell glottic cancer from 2004 to 2012. The treatment groups (radiation and surgery) were compared with respect to several pretreatment covariates including age, race, gender, state where they received treatment, year of diagnosis, and American Joint Committee on @entity5 (AJCC) stage. RESULTS: In analyzing geographic trends, a statistically significant difference in treatment received by region and state was found (P < .0001.). When examining @entity1 demographics, there was no statistically significant difference in treatment by age (P = .5206), AJCC stage (P = .4922), or year of diagnosis (P = .6593). There was a significant difference in racial distribution by treatment (P = .0038), with @entity1 receiving surgery more likely to be black than @entity1 receiving radiation (12% vs. 10%). In analyzing @entity1349 ( @entity1349 ), there was no significant difference in @entity1349 among the four US treatment regions (P = .2508). CONCLUSIONS: Geographic factors impact overall treatment of @entity5 . In addition, it was determined that race was a factor that correlated to differences in treatment modality. Finally, @entity1349 across the United States was determined to be significantly better in @entity1 receiving radiation therapy. LEVEL OF EVIDENCE: 4 Laryngoscope, 2015.

Geographic trends in management of early-stage XXXX .

@entity5 :: ('MESH:D009369', 'Disease') :: ['early-stage glottic cancer', 'Cancer'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity5 :: (MESH:D009369,Disease) :: ['laryngeal cancer']
