BACKGROUND: Tea and coffee are the most commonly consumed beverages in the worldwide. The relationship between tea and coffee consumption on the risk of @entity5 was still unclear. METHODS: Relevant studies were identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013. Observational studies that reported RRs and 95% CIs for the link of tea and coffee consumption on the risk of @entity5 were eligible. A meta-analysis was obtained to combine study-specific RRs with a random-effects model. RESULTS: A total of 2,803 cases and 503,234 controls in 10 independent studies were identified. The overall analysis of all 10 studies, including the case-control and cohort studies, found that tea drinking was not associated with @entity189 (RR=1.03; 95% CI: 0.66-1.61). However, coffee consumption was significantly associated with the @entity189 (RR=1.47; 95% CI: 1.03-2.11). A dose-response relationship between coffee intake and @entity189 was detected; however, no evidence of dose-response link between tea consumption and @entity189 risk was detected. CONCLUSIONS: The results from this meta-analysis of observational studies demonstrate that coffee consumption would increase the @entity5 risk, while tea intake was not associated with risk of @entity189 .

Tea and coffee consumption and risk of XXXX : a systematic review meta-analysis.

@entity5 :: ('MESH:D009369', 'Disease') :: ['laryngeal cancer'] @entity189 :: ('MESH:D002277', 'Disease') :: ['laryngeal carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['laryngeal cancer']
