BACKGROUND: The objective of this study was to investigate the use of cryosurgery and to determine whether there is a role for combined therapy with @entity167 ablation in the treatment of @entity1 with @entity157 . METHODS: Twelve @entity1 with biopsy proven @entity157 underwent ultrasound-guided cryosurgical ablation of their @entity96 . Postoperative @entity167 ablation was performed on those @entity1 who were found to have @entity41 or recurrence after the cryosurgical procedure. RESULTS: Of the 12 @entity1 (9 males, 3 females) the size of the primary @entity5 ranged from 3-13 cm with average size of 7 cm in greatest dimension. Most @entity1 had advanced disease according to the TNM staging system: 9 @entity1 had @entity3480 , 2 Stage III, and 1 Stage II. Three @entity1 had @entity41 after the cryosurgical procedure. The @entity41 was treated with @entity167 ablation. The 1-year survival rate for the entire group was 50% (5 of 10) and the 2-year survival rate was 30% (3 of 10). At last follow-up, 1 @entity1 with an 8-cm @entity5 was disease free for 3 years and another @entity1 with a 13-cm @entity5 was disease free for 2.5 years. Both of these @entity1 had @entity3480 . CONCLUSIONS: The authors found cryosurgery to be promising in the treatment of this extremely aggressive form of @entity5 , with the ability to prolong @entity1 survival. Follow-up treatment with @entity167 ablation is an important adjunct in treating @entity41 and controlling recurrences.

Cryosurgery as a treatment for @entity5 : results, complications, and XXXX ablation.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity41 :: ('MESH:D018365', 'Disease') :: ['residual tumors', 'residual tumor'] @entity96 :: ('MESH:D008113', 'Disease') :: ['liver tumor'] @entity167 :: ('CHEBI:16236', 'Chemical') :: ['alcohol'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity3480 :: ('MESH:C538167', 'Disease') :: ['Stage IVA disease'] @entity157 :: ('MESH:D006528', 'Disease') :: ['hepatocellular carcinoma']
@entity167 :: (CHEBI:16236,Chemical) :: ['alcohol']
