BACKGROUND: Open repair is the gold standard management for @entity439 . Fenestrated @entity439 repair (FEVAR) is indicated for high-risk @entity1 . The long-term outcomes of FEVAR are largely unknown, and there is no Level I comparative evidence. This systematic review and meta-analysis of case series compares elective juxtarenal @entity439 surgery by open repair and FEVAR. METHODS: A systematic literature search was conducted for all published studies on elective repair of @entity439 by FEVAR and open repair. The MEDLINE, EMBASE, and Cochrane databases were searched from 1947 to April 2013. The exclusion criteria were case series of  <10 @entity1 or @entity1756 . The primary outcomes were perioperative mortality and postoperative @entity177 . The secondary outcomes were secondary reinterventions and long-term survival. RESULTS: We identified 35 case series with data on 2326 @entity1 . Perioperative mortality was 4.1% in open repair and FEVAR case series (odds ratio for open repair with FEVAR, 1.059; 95% confidence interval, 0.642-1.747; P  = .822). @entity177 was not significantly different (odds ratio for open repair with FEVAR, 1.136; 95% confidence interval, 0.754-1.713; P  = .542). FEVAR @entity1 had higher rates of secondary reintervention, @entity8 during follow-up, and a lower long-term survival compared with open repair @entity1 . CONCLUSIONS: FEVAR and open repair have similar short-term outcomes but have diverging long-term outcomes that may be secondary to the selection bias of FEVAR being offered to high-risk @entity1 . FEVAR is a favorable option in high-risk @entity1 , and open repair remains viable as the gold standard.

Open repair versus fenestrated XXXX repair of @entity439 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal impairment'] @entity177 :: ('MESH:D051437', 'Disease') :: ['Postoperative renal insufficiency', 'renal insufficiency'] @entity439 :: ('MESH:D000783', 'Disease') :: ['endovascular aneurysm', 'aneurysm', 'juxtarenal aneurysms'] @entity1756 :: ('MESH:D017542', 'Disease') :: ['ruptured aneurysms']
@entity439 :: (MESH:D000783,Disease) :: ['endovascular aneurysm']
