To examine the validity of a newly established "three-odor detection ( @entity63346 )" procedure using one of volatile organic compounds (VOCs), @entity4108 , food-restricted male @entity19 were used. Five animals each were assigned to either @entity63346 or single-odor detection (SOD). @entity63346 was composed of two trainings and one test (TEST) session. @entity19 were trained to discriminate an odor of coffee from no odor and odors of coffee and cheese from no odor in trainings 1 and 2, respectively. In TEST, @entity19 were required to discriminate odors of coffee, cheese, and @entity4108 from no odor. In SOD, @entity19 were required to discriminate an odor of @entity4108 from no odor. Each training or test was conducted once a day until animals achieved a learning criterion (75% correct response rate for 2 consecutive days), or until a maximum number of sessions (20 sessions) was completed. The number of sessions for reaching the learning criterion of animals in TEST (8.2    0.8) was smaller than that of animals in SOD (19.2    0.8). Results indicated that @entity19 in @entity63346 detected low levels of VOCs more rapidly than animals in SOD. I concluded that @entity63346 is a useful procedure for detecting low levels of VOCs.

Evaluation of the ability of XXXX to detect VOCs, using a positive operant reinforcement procedure.

@entity19 :: ('10090', 'Species') :: ['Mice', 'mice'] @entity63346 :: ('MESH:C536561', 'Disease') :: ['TOD'] @entity4108 :: ('MESH:C008281', 'Chemical') :: ['limonene']
@entity19 :: (10090,Species) :: ['mice']
