OBJECTIVE: To compare the neurological outcome of microsurgical clipping versus coiling in @entity1 with anterior circulation @entity439 . STUDY DESIGN: Comparative study. PLACE AND DURATION OF STUDY: Department of Neurosurgery, Lahore General Hospital, Lahore, from January 2010 to December 2013. METHODOLOGY: @entity1 aged 14 - 60 years, with @entity1756 of anterior circulation and World Federation of Neurosurgical Society (WFNS) grades 1, 2 and 3 were included. @entity1 more than 60 years, medically unfit @entity1 and posterior circulation @entity439 and WFNS grades 4 and 5 were excluded. @entity439 sac obliteration was done in randomized manner with microsurgical clipping or coiling. Postoperatively, the @entity1 were assessed and followed-up upto one year for outcome parameters on the bases of WFNS grade and Modified Ranking Scale (mRS) as favourable ( @entity5329 ) and unfavourable ( @entity5329 ). RESULTS: Among 140 subjects selected for study, 70 were included in group A, i.e. coiling and other 70 were in group B, i.e. clipping. The median age of @entity1 in group A was 52.5    10 years and in group B was 51.00    10 years. Overall, 56 (40%) males, 28 (60%) males in each group; and 84 (60%) females, 42 (60%) in each group were included. The male to female ratio in this study was 1:1.5. In group A, i.e. coiling, 27 (38.6%) @entity1 had no disability (grades 1 and 2), 25 (35.7%) were slightly disabled (grade 3) and 18 (25.7%) had moderate disability (grade 4); whereas in group B, i.e. clipping group 23 (32.9%) @entity1 had no disability (grades 1 and 2), 23 (32.9%) were slightly disabled (grade 3) and 24 (34.3%) had moderate disability (grade 4). At one year follow-up, in group A, favourable outcome was achieved in 56 (80%) of @entity1 compared to 48 (68.6%) in group B; whilst, 14 (20%) @entity1 in group Aand 22 (33.1%) in group B showed unfavourable outcome. Although mortality rate was higher in clipping (n=3, 4.3%) as compared to coiling (n=1, 1.4%), but was not statistically significant (p = 0.310). CONCLUSION: Endovascular coiling of anterior circulation @entity439 is safe and as effective and successful as @entity439 clipping and is less invasive also.

Aneurysmal Subarachnoid Hemorrhage: Outcome of XXXX Versus Coiling in Anterior Circulation @entity439 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms', 'aneurysm', 'Aneurysm'] @entity5329 :: ('380836(Tax:10090)', 'Gene') :: ['mRS  <=2', 'mRS > 2'] @entity1756 :: ('MESH:D017542', 'Disease') :: ['ruptured cerebral aneurysm']
@entity439 :: (MESH:D000783,Disease) :: ['Aneurysm Clipping']
