UNASSIGNED: @entity1 with @entity1151 ( @entity1151 ) are often tested for @entity49 , which are hereditary and acquired conditions that predispose to @entity715 . If a @entity74 is identified, then testing is often performed on members of the @entity1 's family. Testing for these conditions can be complex, as the presence of acute @entity715 and antithrombotic therapies can make the results of many tests unreliable. Many risk factors for @entity715 exist that are not routinely assessed by laboratory testing, and it is likely that many @entity74 remain to be discovered. Also, various risk factors for @entity715 interact with one another. Therefore, the results of a laboratory @entity49 evaluation provide a limited ability to assess a @entity1 or family members' risk for future @entity715 , and such testing usually does not provide information that improves a management decision. @entity49 testing is expensive and carries potential risks. This article reviews common @entity49 , their epidemiology and classification, and timing and technical aspects of accurate testing and provides rational suggestions for the use of @entity49 testing in five clinical situations: (1) following provoked @entity1151 (or other @entity1211 ), (2) following unprovoked @entity1211 , (3) in relatives of @entity1 with @entity715 , (4) in female relatives of @entity1 with @entity715 considering @entity172 use, and (5) in female relatives of @entity1 with @entity715 who are considering pregnancy. Published guidelines and guidance statements from professional societies and other groups are also reviewed. Clinicians should carefully consider the relevant risks and benefits before testing @entity1 for @entity49 . When performed, testing should be timed correctly and care should be taken to properly interpret results. New models that incorporate multiple genetic and clinical markers may improve the utility of testing, but these await further research.

Thrombophilic Evaluation in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen'] @entity49 :: ('MESH:D019851', 'Disease') :: ['thrombophilias', 'Thrombophilia', 'thrombophilia'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['PE', 'acute pulmonary embolism'] @entity74 :: ('MESH:D030342', 'Disease') :: ['hereditary thrombophilia conditions', 'hereditary condition'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thromboembolism']
@entity1151 :: (MESH:D011655,Disease) :: ['Acute Pulmonary Embolism']
