1. Arteriovenous differences for @entity493 , @entity2227 and @entity1160 were measured across subcutaneous adipose tissue and forearm muscle in normal subjects. 2. After an overnight fast, adipose tissue showed net production of @entity493 and @entity1160 and uptake of @entity2227 in each of 11 subjects. 3. In seven subjects, adipose tissue blood flow was measured and the measurements were continued for 6 h after eating a mixed meal. The pattern of @entity535 metabolism across the adipose tissue was remarkably little disturbed after the meal, except for a short period of apparent uptake of @entity493 as the concentration of that @entity535 rose. 4. The pattern of @entity535 metabolism across adipose tissue was qualitatively similar to that across the forearm, although it differed quantitatively in that @entity2227 uptake was more prominent (compared with @entity1160 release) in the adipose tissue. 5. The rates of @entity493 and @entity1160 release observed suggest that adipose tissue may play a substantial role in the whole-body production of these @entity1522 .

XXXX metabolism in human subcutaneous adipose tissue in vivo.

@entity1522 :: ('CHEBI:33709', 'Chemical') :: ['amino acids'] @entity2227 :: ('CHEBI:29987', 'Chemical') :: ['glutamate'] @entity1160 :: ('CHEBI:28300', 'Chemical') :: ['glutamine'] @entity535 :: ('CHEBI:33704', 'Chemical') :: ['amino acid'] @entity493 :: ('CHEBI:16449', 'Chemical') :: ['alanine']
@entity535 :: (CHEBI:33704,Chemical) :: ['Amino acid']
