UNASSIGNED: The study concerns the determination of mechanical properties of @entity1 coronary arterial walls with both experimental and constitutive modeling approaches. The research material was harvested from 18 @entity1 (range 50-84 years). On the basis of hospital records and visual observation, each tissue sample was classified according to the stage (0, I, II, III) of @entity731 development ( @entity4696 ). Then, strip samples considered as a membrane with the shape of rectangular parallelepiped were preconditioned and subjected to uniaxial tensile tests in longitudinal (n=27) and circumferential (n=4) direction. With experimental data obtained, the stress-strain characteristics were prepared. Furthermore, tensile strengths and related strains, @entity2693 and tangent modules of elasticity were computed. For a constitutive model of passive mechanical behavior of coronary arteries, values of material parameters were computed. The studies led to the following conclusions. Most importantly, the @entity731 changes affect all the mechanical properties of arterial walls. A progress of @entity4288 contributes to an increase of @entity455 . The highest values of the @entity2693 are obtained for the tissues in the advanced stage of the disease. We were also able to observe that gradual calcification, progression of @entity731 and degradation of collagen in the tissue caused a decrease of tensile strengths and related strains. Finally, a comparison made for the tissues with the advanced @entity4696 showed that the tensile strengths and strains were much higher in the case of the samples with the circumferential orientation rather than those with the longitudinal one.

Experimental and constitutive modeling approaches for a study of biomechanical properties of XXXX coronary arteries.

@entity1 :: ('9606', 'Species') :: ['human', 'patients'] @entity455 :: ('MESH:D014652', 'Disease') :: ['vascular stiffness'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic', 'atherosclerosis'] @entity4696 :: ('MESH:D003865', 'Disease') :: ['SAD'] @entity4288 :: ('MESH:D001161', 'Disease') :: ['arteriosclerosis'] @entity2693 :: ('MESH:C566112', 'Disease') :: ['stiffness coefficients']
@entity1 :: (9606,Species) :: ['human']
