The @entity3146 ( @entity3146 ) classification which proposes new approaches to the diagnosis, terminology and differential diagnosis of @entity75 of the breast was applied to a series of female @entity1 comprising @entity1722 oncogene expression which may serve as an adjunct to the morphology by immunohistochemistry. The study was performed using the data of 94 @entity1 . There was no difficulty encountered in the diagnosis of @entity1373 ( @entity1373 ). In @entity1 with @entity1373 ( @entity1373 ), the diagnosis could be made by using the 2-mm rule of the @entity3146 classification in @entity1 who exhibited cytologic and structural characteristics of @entity3821 ( @entity3821 ) alone or in conjunction with classical @entity1373 patterns. However, in lesions that mimicked classical @entity1373 patterns despite displaying cytological features of in situ @entity189 , the experience and view point of the pathologist played a more prominent role. When the @entity3146 classification criteria were applied to grade @entity3821 , although the system was found to be practical, it did not provide adequate differentiation in intermediate grade (grade II- @entity3146 2) @entity1 and further improvement was considered desirable. Fourty-five cases (47.8%) @entity1373 , 19 (20.2%) @entity1373 , and 30 (31.9%) were @entity3821 . There were statistically significant differences in the levels of @entity1722 oncogene expression between @entity1373 , @entity1373 and @entity3821 (p<0.001). In DCISs, grade, cell size, pleomorphic nuclear atypia showed statistically significant associations with @entity1722 oncogene expression. These results suggest that @entity1722 oncogene expression is a valuable marker in the differential diagnosis and prognostic evaluation of @entity1 with @entity75 .

@entity1722 oncogene expression in XXXX of the breast.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3821 :: ('MESH:D002285', 'Disease') :: ['Ductal Carcinoma in Situ', 'DCIS lesions', 'DCIS'] @entity75 :: ('MESH:D001927', 'Disease') :: ['intraductal proliferative lesions'] @entity1373 :: ('MESH:D006965', 'Disease') :: ['Atypical Ductal Hyperplasia', 'IDH', 'intraductal hyperplasia', 'AIDH'] @entity189 :: ('MESH:D002277', 'Disease') :: ['carcinomas'] @entity3146 :: ('MESH:D018290', 'Disease') :: ['DIN', 'ductal intraepithelial neoplasia'] @entity1722 :: ('2064', 'Gene') :: ['C-erbB2', 'c-erbB2']
@entity75 :: (MESH:D001927,Disease) :: ['intraductal proliferative lesions']
