BACKGROUND: @entity1381 ( @entity1381 ) is characterized by @entity810 , @entity2106 and @entity882 . AIM: To describe the characteristics of @entity1 with the diagnosis of @entity1381 in Chile, and to identify the most reliable early predictors of morbidity and mortality. MATERIAL AND METHODS: The clinical records of @entity1 with @entity1381 aged less than 15 years, attended between January 1990 and December 2003 in 15 hospitals, were reviewed. Demographic, clinical, biochemical, hematological parameters, morbidity and mortality were analyzed. RESULTS: A cohort of 587 @entity1 aged 2 to 8 years, 48% males, was analyzed. Ninety two percent had @entity294 . At the moment of diagnosis, @entity1696 was observed in 39% of the @entity1 , @entity101 in 45% and @entity410 in 17%. Forty two percent required renal replacement therapy (RRT) and peritoneal dialysis was used in the majority of cases (78%). The most frequently isolated etiological agent was @entity526 . Mortality rate was 2.9% in the acute phase of the disease and there was a positive correlation between mortality and @entity1696 , @entity410 , white blood cell count (WCC)>20.000/mm3 and requirements of renal replacement therapy (p<0.05). Twelve percent of @entity1 evolved to @entity177 and the risk factors during the acute phase were the need for renal replacement therapy, @entity1696 , WCC>20.000/mm3, @entity410 and @entity101 . CONCLUSIONS: The present study emphasizes important clinical and epidemiological aspects of @entity1381 in a Chilean pediatric population.

[ XXXX in Chile: clinical features, evolution and prognostic factors].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity882 :: ('MESH:D013921', 'Disease') :: ['thrombocytopenia'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity177 :: ('MESH:D051437', 'Disease') :: ['chronic renal failure'] @entity810 :: ('MESH:D058186', 'Disease') :: ['acute renal failure'] @entity1381 :: ('MESH:D006463', 'Disease') :: ['Hemolytic-uremic syndrome', 'HUS'] @entity1696 :: ('MESH:D001002', 'Disease') :: ['anuria'] @entity2106 :: ('MESH:D011697', 'Disease') :: ['microangiopathic hemolytic anemia'] @entity526 :: ('562', 'Species') :: ['Escherichia coli']
@entity1381 :: (MESH:D006463,Disease) :: ['Hemolytic-uremic syndrome']
