The possible methods of preventing @entity583 have been discussed. The desirability of prevention in the total problem of @entity583 is stressed. The methods consist of the prevention of the underlying @entity453 , and the secondary prevention of @entity741 contributed by other factors than those presumed to relate to @entity731 . In the primary prevention of @entity453 the two major risk factors are elevation of serum lipids and of blood pressure. The benefits to be achieved by reduction of elevation of both of these abnormalities are discussed. Both require a long-term approach starting as early in life as possible. The major methods of prevention or retardation of @entity63 irrespective of @entity453 involve discontinuance of cigarette-smoking and a program of increased physical activity. In addition, prevention or correction of @entity6582 , @entity417 or @entity49 should be included. The use of @entity26 , in higher percentage or at higher pressure than in the atmosphere, surgical intervention to improve the myocardial blood supply and pharmacologic agents to improve myocardial metabolism are also considered. Quantitation of the benefit of preventive programs is still impossible. Benefit from lowering blood lipids and blood pressure requires long-term therapy begun early in life. Discontinuance of cigarette smoking and increasing the amount of physical activity offer reasonable assurance of immediate benefit. So also does correction of @entity1503 . Pharmacologic agents and surgery to improve coronary blood flow still require further evaluation.

Prevention of XXXX .

@entity6582 :: ('MESH:D011086', 'Disease') :: ['polycythemia'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anemia'] @entity63 :: ('MESH:D007511', 'Disease') :: ['coronary ischemia'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerosis'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity49 :: ('MESH:D019851', 'Disease') :: ['hypercoagulability'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['hematologic abnormalities'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary artery disease', 'coronary atherosclerosis'] @entity741 :: ('MESH:D017202', 'Disease') :: ['myocardial ischemia'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction']
@entity583 :: (MESH:D009203,Disease) :: ['myocardial infarction']
