OBJECTIVE: To systematically review the literature and synthesize data on the diagnostic performance of a 12-hour urine collection for @entity644 in pregnant @entity1 with suspected @entity1468 . DATA SOURCES: We performed a literature search of PubMed, Embase, Scopus, ClinicalTrials.gov, and CINAHL through February 2014 using key words related to gestational @entity101 , @entity1468 , and @entity644 . METHODS OF STUDY SELECTION: Studies that contained results of both the 12-hour and 24-hour urine collection in the same @entity1 were eligible. TABULATION, INTEGRATION, AND RESULTS: Three independent reviewers abstracted test performance characteristics from each study for the performance of a 12-hour urine collection for the diagnosis of @entity644 defined as 300 mg in 24 hours. Diagnostic meta-analysis was performed to obtain summary statistics. Heterogeneity was assessed using the Cochrane Q or I. Receiver operating characteristic curve analysis was used to assess the optimal diagnostic cutpoint for @entity644 from a 12-hour urine collection. Stratified analysis was performed based on whether @entity1 were on bed rest during urine collection. A total of seven studies met inclusion criteria. The 12-hour urine protein was overall highly predictive of @entity644 on 24-hour urine collection area under receiver operating characteristic curve: 0.97 (95% confidence interval [CI] 0.95-0.98). The pooled sensitivity was 92% (95% CI 86-96) and specificity was 99% (95% CI 75-100). The optimal cutpoint based on the receiver operating characteristic curve was 150 mg of protein on 12-hour collection. CONCLUSION: A 12-hour urine collection compares favorably with a 24-hour urine collection for the diagnosis of @entity644 in @entity1 with suspected @entity1468 and has the advantage of convenience and improved clinical efficiency.

The Utility of 12-Hour Urine Collection for the XXXX : A Systematic Review and Meta-analysis.

@entity1 :: ('9606', 'Species') :: ['women', 'patients'] @entity644 :: ('MESH:D011507', 'Disease') :: ['proteinuria'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['preeclampsia'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension']
@entity1468 :: (MESH:D011225,Disease) :: ['Diagnosis of Preeclampsia']
