This study was designed to clarify the clinical and pathologic features of diffusely infiltrative @entity957 of the esophagus. Diffusely infiltrative @entity957 were classified grossly into two types, namely, @entity5223 and @entity189 . There were seven @entity1 with the former type and three with the latter type. @entity5223 was associated with a prominently thickened esophageal wall with strictures, whereas @entity189 demonstrated thickening of the esophageal wall without strictures. Microscopically, all @entity1 had lymph node metastases and lymphatic invasion. Blood vessel invasion was found in seven @entity1 and extranodal invasion was found in seven. The prognosis of @entity1 with both types of @entity189 was extremely poor. Only two @entity1 who underwent curative surgery as well as chemoradiotherapy survived for more than 1 year. Therefore, further morphological studies on the early stages of diffusely infiltrating @entity418 should be performed. New treatment strategies such as intensive preoperative chemoradiotherapy based on sensitivity tests in individual @entity1 will be required for treating the advanced stages of this disease.

Diffusely infiltrative XXXX of the esophagus.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma', 'squamous cell carcinomas'] @entity189 :: ('MESH:D002277', 'Disease') :: ['nonscirrhous-type carcinoma', 'carcinoma', 'nonscirrhous carcinoma'] @entity5223 :: ('MESH:D002293', 'Disease') :: ['scirrhous carcinoma', 'Scirrhous-type carcinoma'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal carcinoma']
@entity957 :: (MESH:D002294,Disease) :: ['squamous cell carcinoma']
