BACKGROUND: Radiation is essential for function preservation in the management of soft tissue @entity242 (STS). One of the advantages of brachytherapy is that it allows for specific localization of radiation dose to the @entity5 bed. We examined the results of our clinical experiences with immediate postoperative @entity1168 ( @entity1168 ) brachytherapy and external beam radiation treatment (EBRT) for STS. METHODS: A total of 17 @entity1 (11 primary and six recurrent) between 1995 and 1999 were included in this review. The inclusion criteria for @entity1168 and EBRT were as follows: (1) high-grade @entity5 , (2) low-grade @entity5 of > or = 10 cm, (3) recurrent @entity5 abutting or invading critical structures and (5) positive margin. The catheters (six French) were placed parallel to the long axis of the @entity5 with a 1-1.5 cm spacing in between. If necessary, muscle or gel-foam was placed over the critical structures to maintain a minimum space of 0.5 cm from the catheters. On postoperative day 6, @entity1 received @entity1168 (2-3 Gy/fraction x6, twice daily). Three weeks later, @entity1 received EBRT (total 36-60 Gy). The follow-up duration was between 13 and 60 months (median 31 months). RESULTS: There was no local failure within the radiation field in any of the @entity1 . One @entity1 required wound revision for @entity245 after brachytherapy. During EBRT, most @entity1 experienced only mild erythema (grade 1 or 2 skin reaction). In long-term follow-up, there were no @entity1 with @entity16 or significant @entity82 . CONCLUSIONS: Our results suggest that immediate postoperative @entity1168 with a total dose of 12-18 Gy over 3 days is an effective treatment combined with EBRT in the management of STS.

High dose rate interstitial brachytherapy in soft tissue XXXX : technical aspects and results.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity242 :: ('MESH:D012509', 'Disease') :: ['sarcoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumor, (4) tumor'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neuropathy'] @entity245 :: ('MESH:D002658', 'Disease') :: ['delayed healing'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['HDR', 'high dose rate']
@entity242 :: (MESH:D012509,Disease) :: ['sarcoma']
