OBJECTIVES: To study the clinical characteristics, treatment modalities, and outcome of @entity1 with superior @entity5 who underwent surgery over a 15-year period. DESIGN: Retrospective clinical study. METHODS: Clinical records of all @entity1 operated on for superior @entity5 by the same surgical team between 1988 and 2002 were reviewed retrospectively. RESULTS: Sixty-seven @entity1 were operated on in this period. All the @entity1 underwent en bloc lung and chest wall resection. Surgical approaches were as follows: posterolateral thoracotomy according to Paulson (n = 33), combined transcervical and transthoracic approach (n = 33), and isolated transcervical approach (n = 1). Types of pulmonary resection included lobectomies (n = 59), pneumonectomies (n = 2), and wedge resections (n = 6). Pathologic stages were IIB, IIIA, and IIIB in 49 cases, 12 cases, and 6 cases, respectively. Resection was complete in 55 @entity1 (82%). Operative mortality was 8.9% (n = 6). Postoperative treatment was administered in 53 @entity1 (radiotherapy, n = 42; chemoradiotherapy, n = 9; and chemotherapy, n = 2). Overall 2-year and 5-year survival rates were 54.2% and 36.2%, respectively. Five-year survival was significantly higher after complete resection than after incomplete resection (44.9% vs 0%, p = 0.000065). The presence of associated major illness negatively affected the outcome (5-year survival, 16.9% vs 52%; p = 0.043). Age, @entity353 , @entity1576 , @entity5 size, presence of @entity66 , and histologic type did not influence the long-term outcome. At multivariate analysis, only the completeness of resection and the absence of associated major comorbidities had an independent positive prognostic value. CONCLUSIONS: Superior @entity5 remains an extremely severe @entity558 , but long-term survivals may be achieved in a large percentage of cases. The presence of associated major illness and the completeness of resection are the two most important factors affecting the long-term outcome.

Surgical treatment of superior XXXX : results and prognostic factors.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity558 :: ('MESH:C536528', 'Disease') :: ['condition'] @entity353 :: ('MESH:D015431', 'Disease') :: ['weight loss'] @entity66 :: ('MESH:D004194', 'Disease') :: ['nodal disease'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'sulcus tumors', 'sulcus tumor'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory impairment']
@entity5 :: (MESH:D009369,Disease) :: ['sulcus tumors']
