UNASSIGNED: Extracranial carotid artery occlusion or high-grade @entity850 with concomitant @entity999 causes severe @entity385 and shows poor response rates to @entity5275 ( @entity5275 ). Endovascular therapy (EVT) utilizing thrombectomy assisted by carotid stenting was long considered risky because of procedural complexities and necessity of potent platelet inhibition-in particular following @entity5275 . This study assesses the benefits and harms of thrombectomy assisted by carotid stenting and identifies factors associated with clinical outcome and procedural complications. Retrospective single-center analysis of 47 consecutive @entity64 @entity1 with @entity432 or high-grade @entity850 and concomitant intracranial embolus treated between September 2011 and December 2014. Benefits included early improvement of @entity64 severity (NIHSS  >=   10) or complete remission within 72  h and favorable long-term outcome ( @entity5329 ). Harms included complications during and following EVT. Mean age was 64.3  years (standard deviation   12.5), 40 (85  %) @entity1 received @entity5275 initially. Median NIHSS was 16 (inter-quartile range 14-19). Mean time from @entity64 onset to recanalization was 311  min (standard deviation   78.0). Early clinical improvement was detected in 22 (46  %) @entity1 . Favorable outcome at 3  months occurred in 32 (68  %) @entity1 . Expedited @entity1 management was associated with favorable clinical outcome. Two (4  %) @entity1 experienced symptomatic @entity548 . Eight (17  %) @entity1 experienced stent @entity715 . Four (9  %) @entity1 died. Thrombectomy assisted by carotid stenting seems beneficial and reasonably safe with a promising rate of favorable outcome. Nevertheless, adverse events and complications call for additional clinical investigations prior to recommendation as clinical standard. Expeditious @entity1 management is central to achieve good clinical outcome.

Thrombectomy assisted by carotid stenting in acute XXXX management: benefits and harms.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity5329 :: ('380836(Tax:10090)', 'Gene') :: ['mRS   <=  2'] @entity5275 :: ('MESH:D015819', 'Disease') :: ['IVT', 'intravenous thrombolysis'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhage'] @entity999 :: ('MESH:D020766', 'Disease') :: ['intracranial embolism'] @entity432 :: ('MESH:D001157', 'Disease') :: ['carotid occlusion'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity385 :: ('MESH:D002544', 'Disease') :: ['ischemic stroke']
@entity385 :: (MESH:D002544,Disease) :: ['ischemic stroke']
