BACKGROUND: @entity3562 has been identified as a risk factor for @entity453 ( @entity453 ). South Asians appear to have a high incidence of @entity453 , while East Asians have a very low incidence. HYPOTHESIS: The present study was undertaken because the relative association of plasma @entity1255 levels (PH) with @entity453 in South Asians (SA = Indian, Pakistani, @entity3595 Lankan) and East Asians (EA = Chinese, Japanese) is not known. METHODS: Fasting PH were drawn on all @entity1 with @entity453 of SA (age 62.4+/-1.1 years, 72 @entity1 , 14 @entity1 ) and EA (age 61.8+/-3.0 years, 13 @entity1 , 4 @entity1 ) descent. These were compared with PH available from Caucasian (CA) @entity1 (age 61.1+/-1.1 years, 89 @entity1 , 17 @entity1 ) with @entity453 . RESULTS: The PH in SA, EA, and CA @entity1 were 11.0+/-0.5, 7.6+/-0.5, and 10.8+/-0.6 micromol/l, respectively (p<0.001 between EA and SA/CA). Percentages of SA, EA, and CA with elevated PH (> 12.0 micromol/l) were 33.7, 5.9, and 28.2%, respectively. There were no significant differences in the lipid subfractions between the SA and EA group. History of smoking was significantly higher in the EA (52.9 vs. 26.2%), while @entity101 and @entity6 had similar prevalences. CONCLUSION: Significant differences in PH of SA versus EA @entity1 with @entity453 exist. The relative contribution of @entity1255 in the development of @entity453 appears to be less in EA immigrants. In contrast, the association between @entity453 and PH in SA immigrants appears to be similar to that of Caucasians.

Possible ethnic differences in plasma @entity1255 levels associated with XXXX between south Asian and east Asian immigrants.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes mellitus'] @entity1255 :: ('MESH:D006710', 'Chemical') :: ['homocysteine'] @entity3595 :: ('6717', 'Gene') :: ['Sri'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'coronary artery disease'] @entity3562 :: ('MESH:D020138', 'Disease') :: ['Hyperhomocysteinemia']
@entity453 :: (MESH:D003324,Disease) :: ['coronary artery disease']
