@entity12874 polymerase (PARP) synthesizes @entity12874 in response to DNA strand breaks using @entity2125 + as a substrate. It leads to consequences for metabolism not only on a cellular level, but also on a tissue level, among others: NAD+ and @entity855 depletion. @entity6112 ( @entity6112 ) in @entity291 is supposed to be connected with the imbalance between production and neutralization of reactive @entity26 species, leading to oxidative damage to DNA, lipids and proteins. The aim of this preliminary study was to detect the presence of PARP in @entity291 placenta and to describe the enzyme with respect to type of placental tissue, time and mode of delivery. Placentomes, collected after spontaneous delivery or caesarian section, were divided into maternal and foetal parts of placenta, homogenized, and subjected to electrophoresis. @entity291 were divided into six groups as follows: (A) caesarian section before term with @entity6112 , (B) caesarian section before term without @entity6112 , (C) spontaneous delivery at term with @entity6112 , (D) spontaneous delivery at term without @entity6112 , (E) caesarian section at term with @entity6112 , (F) caesarian section at term without @entity6112 . PARP was detected by Western blotting using commercially available bovine anti PARP antibody. Bands referred to as @entity291 PARP standard were present in all examined tissues as well as the products of its cleavage. However, the patterns of bands were different with respect to type of tissue, time, and mode of delivery. Further experiments on detailed relationship between PARP activity and the process of releasing and retaining of @entity291 placenta are necessary.

@entity12874 polymerase in XXXX retained and not retained placenta.

@entity2125 :: ('MESH:D009243', 'Chemical') :: ['NAD'] @entity6112 :: ('MESH:D016055', 'Disease') :: ['Retention of foetal membranes', 'RF'] @entity12874 :: ('MESH:D011064', 'Chemical') :: ['poly(ADP-ribose)', 'Poly(ADP-ribose)'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity291 :: ('9913', 'Species') :: ['Cows', 'cows', 'bovine'] @entity855 :: ('MESH:D000255', 'Chemical') :: ['ATP']
@entity291 :: (9913,Species) :: ['bovine']
