Despite a high symptom burden, little is known about the incidence or predictors of hospitalization among @entity463 @entity1 , including risks during chemoradiation (CRT). We studied 196 consecutive newly diagnosed @entity463 @entity1 treated at our institution from 2006-2010. @entity137 data were reviewed during and after the CRT phase, defined as the period between diagnosis and 6  weeks after radiotherapy completion. Logistic regression and proportional hazards modeling identified predictors of hospitalization and @entity1349 ( @entity1349 ). Median age was 59  years (range, 23-90) and 83  % had Karnofsky performance status (KPS) score  >=   70. Twenty-six percent of @entity1 underwent gross total resection, 77  % received  >=   59.4  Gy of radiotherapy, and 89  % received concurrent @entity2903 . Median @entity1349 was 15.6  months (IQR, 8.5-26.8  months). Forty-three percent of @entity1 were hospitalized during the CRT phase; @entity1349 was 10.7 vs. 17.8  months for @entity1 who were vs. were not hospitalized, respectively (P  <  .001). Nearly half of the hospitalizations were due to generalized weakness (17  % of hospitalizations), @entity410 (16  %), or @entity1211 (13  %). On multivariate analysis, age (odds ratio [OR], 1.03; 95  % CI, 1.002-1.060; P  =  .034) and KPS (OR, 0.95; 95  % CI, 0.93-0.97; P  <  .001) were associated with risk of hospitalization. Hospitalization during the CRT phase was associated with decreased @entity1349 (adjusted hazard ratio, 1.47; 95  % CI, 1.01-2.13; P  =  .043), after adjustment for known prognostic factors. Hospitalization during the CRT phase is common among @entity463 @entity1 in the @entity2903 era and is associated with shorter @entity1349 .

Incidence, risk factors, and reasons for hospitalization among XXXX @entity1 receiving chemoradiation.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizures'] @entity137 :: ('MESH:D064420', 'Disease') :: ['Toxicity'] @entity2903 :: ('MESH:C047246', 'Chemical') :: ['temozolomide'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thromboembolism'] @entity463 :: ('MESH:D005909', 'Disease') :: ['glioblastoma'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity463 :: (MESH:D005909,Disease) :: ['glioblastoma']
