BACKGROUND: This study was undertaken to evaluate the long-term prognostic significance of conventional peritoneal cytology in @entity1 with advanced @entity14 after curative resection. METHODS: A review was performed of 189 @entity1 who underwent curative resection for @entity1803 /T4 @entity694 and upper/middle rectum between March 1987 and December 1991. @entity1 outcomes were reviewed retrospectively. Peritoneal cytology was performed before manipulation of the @entity5 . Intraoperatively, 50 ml of saline were instilled and 20 ml were reaspirated for cytology. In all @entity1 , Papanicolaou and Giemsa stainings were performed to detect intraperitoneal free @entity5 cells. RESULTS: The median follow-up was 103 months. Malignant cells were identified in peritoneal washings from 11 @entity1 (5.8%). Of the 11 @entity1 with positive cytology, six (54.5%) developed recurrence and peritoneal recurrence was observed in four (36.4%). In contrast, of the 178 @entity1 with negative cytology, 46 (25.8%) developed recurrence and peritoneal recurrence was observed in four (2.2%). The peritoneal recurrence rate was significantly increased (P = 0.0004) in the @entity1 with positive cytology. The @entity5 -specific 10-year survival rates for the @entity1 with positive and negative cytology were 45.5 and 80.3%, respectively (P = 0.0051). Multivariate analysis (Cox proportional hazard model) revealed that peritoneal cytology (positive: P = 0.0256) and lymph node @entity3 ( @entity477 : P = 0.0004) were independent predictors of @entity5 -specific survival. CONCLUSION: Conventional peritoneal cytology serves as a new prognostic marker after curative resection in @entity1 with advanced @entity14 . It appears to be a useful diagnostic procedure for predicting recurrence, especially peritoneal recurrence.

Long-term prognostic value of conventional peritoneal cytology after curative resection for XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'Patient'] @entity1803 :: ('7694', 'Gene') :: ['pT3'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity477 :: ('351', 'Gene') :: ['pN2'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis'] @entity694 :: ('MESH:D003110', 'Disease') :: ['carcinoma of the colon']
@entity14 :: (MESH:D015179,Disease) :: ['colorectal carcinoma']
