OBJECTIVE: An earlier investigation reported a five-fold increase in @entity0 risk among @entity1 who smoked during pregnancy. Using a similar design, we re-examined this hypothesis. METHODS: The source population comprised Massachusetts residents who gave birth between 1987 and 1999 with a birth record in the Massachusetts Vital Statistics Registry. Cases were diagnosed with @entity0 between 1988 and 2000 at ages 25-55 with a record in the Massachusetts Cancer Registry. Three controls were matched to each case on maternal age, year of giving birth, and birth facility. Information on smoking, the matched factors, and potential confounders were collected from the birth certificate. The data were analyzed using conditional logistic regression. RESULTS: After adjusting for potential confounders, @entity1 who smoked during pregnancy did not have an increased risk of @entity0 compared to @entity1 who did not smoke during pregnancy (relative risk = 1.0, 95% Confidence interval CI = 0.81-1.2). We observed no dose response relation between number of cigarettes smoked per day during pregnancy and @entity0 risk. There was no evidence that our results were biased by misclassification from @entity1 inaccurately reporting their smoking status. CONCLUSION: In contrast to the previous study, we did not observe an increased risk of @entity0 in @entity1 who smoked during pregnancy.

A null association between smoking during pregnancy and XXXX using Massachusetts registry data (United States).

@entity1 :: ('9606', 'Species') :: ['women'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
