STUDY DESIGN: Retrospective study. OBJECTIVES: To model the effect of time since @entity1576 in spinal cord injured-individuals and to investigate the effect of @entity1 characteristics. SETTING: A total of 173 @entity1 who sustained a @entity1566 between 1966 and April 2013 and who had previously participated in research or who underwent clinically indicated outpatient respiratory function tests at the Austin Hospital in Melbourne, Australia, were included in the study. At least two measurements over time were available for analysis in 59 @entity1 . METHODS: Longitudinal data analysis was performed using generalised linear regression models to determine changes in respiratory function following @entity1566 from immediately post injury to many years later. Secondly, we explored whether injury severity, age, gender and body mass index (BMI) at injury altered the time-dependent change in respiratory function. RESULTS: The generalised linear regression model showed no significant change (P=0.276) in respiratory function measured in (forced) vital capacity ((F)VC) after the @entity1566 . However, significant (P<0.05) differences in respiratory function over time were found when categorising age and BMI. CONCLUSION: This clinical cohort with long-term, repeated measurements of respiratory function showed no significant overall change in respiratory function over 23 years. However, a decline in respiratory function over time was observed in subgroups of individuals older than 30 years at the onset of injury and in those with a BMI>30   kg   m(-2).

Long-term change in respiratory function following XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'people'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['injury on longitudinal respiratory function measures'] @entity1566 :: ('MESH:D013119', 'Disease') :: ['spinal cord injury']
@entity1566 :: (MESH:D013119,Disease) :: ['spinal cord injury']
