UNASSIGNED: Our bi-specialty clinic was established to systematically investigate @entity1 with suspected peri-operative @entity56 . Four hundred and ten @entity1 were studied; 316 following an intra-operative reaction ('postoperative' group) and 94 with a previous history of reaction, referred before undergoing anaesthesia ('pre-operative' group). In the postoperative group, 173 (54.7%) were diagnosed with IgE-mediated reactions: 65 (37.6%) to neuromuscular blocking drugs; 54 (31.2%) antibiotics; 15 (8.7%) @entity1216 and 12 (6.9%) patent blue dye. Reactions were severe in 114 @entity1 (65.9%). All reactions to patent blue dye were severe. We identified IgE sensitisation in 22 (13.2%) cases with isolated mucocutaneous reactions. Only 173 (54.7%) patients had serum tryptase samples taken. Referrers' suspected causal agent was confirmed in only 37.2% of @entity1 . Of 94 @entity1 reviewed 'pre-operatively', 29 (30.8%) were diagnosed with @entity10284 reactions, reinforcing the importance of investigating this group of @entity1 . Knowledge of the range of causative agents identified in our study should guide the investigation of suspected peri-operative @entity56 .

Anaesthesia-associated XXXX : seven years' data from a British bi-specialty clinic.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1216 :: ('MESH:D002710', 'Chemical') :: ['chlorhexidine'] @entity10284 :: ('MESH:D006969', 'Disease') :: ['IgE-mediated hypersensitivity'] @entity56 :: ('MESH:D004342', 'Disease') :: ['hypersensitivity reactions']
@entity56 :: (MESH:D004342,Disease) :: ['hypersensitivity reactions']
