BACKGROUND: This study was performed to evaluate the impact of baseline characteristics and treatment methods on the outcome of @entity703 ( @entity359 ). METHODS: This was a pooled analysis of individual data of 441 @entity1 with @entity359 retrieved from 58 studies and 3 institutional series. RESULTS: Ninety-three @entity1 underwent nephrectomy, 163 partial nephrectomy/enucleation, 128 embolisation, 19 cryoablation, 6 radiofrequency ablation, and 32 conservative treatment. Their mean follow-up period was 44.5  months. @entity1 who experienced major @entity548 at presentation had significantly larger @entity5 than did those without @entity548 (mean diameter, 10.1 vs. 5.9  cm, respectively; p   <   0.0001). A total of 9.4  % and 26.4  % of @entity548 @entity5 had a diameter of <4 and <6  cm, respectively. A @entity5 diameter of >= 8.0  cm (hazard ratio, 2.07; 95  % confidence interval, 1.20-4.77) and the treatment method (p   =   0.001) were independent predictors of re-intervention. The risk of re-intervention was significantly higher after embolisation, particularly for large @entity5 (5-year rate of freedom from re-intervention: diameter of >= 8.0  cm, 49.2  %; diameter of <8.0  cm, 74.8  %; p   =   0.018). Conservatively treated AMLs had a mean baseline diameter of 3.2        2.7  cm; after 41  months, their mean diameter was 3.7        3.1  cm (p   =   0.109). CONCLUSIONS: The prevalence of major @entity548 is high in sporadic AMLs with a diameter of >6  cm. These results suggest that conservative treatment can be considered in AMLs of <6  cm in diameter. Among current treatment methods, embolisation was associated with a significantly higher risk of re-intervention. Further studies are needed to define risk factors for @entity548 and assess the relative benefits of different treatment modalities.

Treatment of renal angiomyolipoma: pooled analysis of individual XXXX data.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumours', 'tumour'] @entity359 :: ('MESH:D018207', 'Disease') :: ['AML'] @entity703 :: ('MESH:D007680', 'Disease') :: ['sporadic renal angiomyolipoma']
@entity1 :: (9606,Species) :: ['patient']
