BACKGROUND: @entity1726 is associated with a variety of @entity25 . The @entity935 agonists (DA) @entity399 and @entity25049 were recently implicated in causing " @entity25 " and motor vehicle accidents. METHODS: In order to determine the overall rate of subjective @entity25 in @entity1726 and to determine if any factors, including specific medications, correlate with sleep pathology, the authors surveyed consecutive @entity1 with @entity1726 seen over a 3-month period in a @entity717 Clinic. The authors collected demographic and medication data, and the @entity1 completed the Epworth Sleepiness Scale (ESS), questions assessing the presence of @entity4531 ( @entity4531 ), a modified National Sleep Foundation sleep survey, and specific questions regarding falling asleep while driving. RESULTS: A total of 320 @entity1 completed the questionnaire. The authors eliminated 17, six for incomplete data and 11 for having a primary diagnosis other than @entity1726 . The mean age of the remaining 303 @entity1 was 67.1 +/- 10.7 years, and the mean duration of @entity1726 was 9.1 +/- 5.7 years. The ESS scores averaged 11.1 +/- 5.9, and in 50.2% of @entity1 the score was abnormally high (>10). Stepwise regression analysis found that sleepiness correlated with longer duration of @entity1726 (p < 0.001), more advanced @entity1726 (p < 0.004), male sex (p < 0.001), and the use of any DA (p < 0.003). The soporific effects of the three most common DA ( @entity399 , @entity25049 , and @entity4088 ) were similar. Falling asleep while driving was reported by 63/279 (22.6%) of current drivers and correlated with higher ESS scores (p < 0.05). Other @entity25 , including @entity4531 , were also frequently reported. CONCLUSION: @entity25 is common in @entity1726 and correlates with more advanced and longer duration of @entity1726 , and male sex. The DA were also independently associated with @entity25 , but in this group, no single DA was more culpable than the others.

XXXX and other @entity25 in Parkinson's disease.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity25049 :: ('MESH:C046649', 'Chemical') :: ['ropinirole'] @entity935 :: ('MESH:D004298', 'Chemical') :: ['dopamine'] @entity4088 :: ('MESH:D010479', 'Chemical') :: ['pergolide'] @entity1726 :: ('OMIM:168600', 'Disease') :: ['PD'] @entity4531 :: ('MESH:D012148', 'Disease') :: ['restless legs syndrome', 'RLS'] @entity399 :: ('MESH:C061333', 'Chemical') :: ['pramipexole'] @entity717 :: ('MESH:D009069', 'Disease') :: ['Movement Disorders'] @entity25 :: ('MESH:D012893', 'Disease') :: ['sleep disorders', 'Daytime sleepiness', 'daytime sleepiness', 'sleep problems', 'sleep attacks']
@entity25 :: (MESH:D012893,Disease) :: ['Daytime sleepiness']
