UNASSIGNED: Diffuse low-grade @entity11 are rare primitive @entity5 of adults. These @entity5 progress continuously over time and then turn to a higher grade of @entity5 associated with @entity16 , leading ultimately to @entity204 . @entity5 size is one of the most important prognostic factors. Thus, it is of great importance to be able to assess the volume of the @entity5 during the @entity1 ' monitoring. MRI is nowadays the recommended modality to achieve this. Furthermore, if surgery remains the first option for diffuse low-grade @entity11 , chemotherapy is increasingly used (before or after a possible surgery). However, crucial and difficult questions remain to be answered: identifying subgroups of @entity1 who could benefit from chemotherapy, determining the best time to initiate chemotherapy, defining the duration of chemotherapy and evaluating the optimal time to perform surgery, or otherwise radiotherapy. In this study, we propose to help clinicians in decision-making, by designing new predictive models dedicated to the evolution of the diameter of the @entity5 . Two proposed statistical models (linear and exponential) have been validated on a database of 16 @entity1 whose @entity2903 -based chemotherapy lasted between 14 and 32 months, with an average duration of 22.8 months. The selection of the most appropriate model has been achieved with the corrected Akaike's Information Criterion. The results are very promising, with coefficients of determination varying from 0.79 to 0.97 with an average value of 0.90 for the linear model. This shows it is possible to alert the clinician to a change in the @entity5 diameter's dynamics.

Predictive models for diffuse low-grade XXXX @entity1 under chemotherapy.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cerebral tumours', 'Tumour', 'malignancy', 'tumors'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurological disability'] @entity11 :: ('MESH:D005910', 'Disease') :: ['gliomas'] @entity2903 :: ('MESH:C047246', 'Chemical') :: ['temozolomide'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity11 :: (MESH:D005910,Disease) :: ['glioma']
