CONCLUSIONS: Low dose oral @entity7855 tablets are safe and effective to decrease the lesions volume in some @entity600 @entity1 , especially with @entity75 or mixed type. OBJECTIVE: To evaluate the efficacy and safety of oral @entity7855 in treatment of pediatric head and neck @entity600 ( @entity600 ). SUBJECTS AND METHODS: In this open-label study, 21 @entity1 diagnosed with @entity600 were given oral @entity7855 and stopped at week 24. Volume change of lesions compared with baseline was used to evaluate therapeutic outcome. The improvement of various symptoms and the adverse effects of @entity7855 were recorded during the follow-up period. RESULTS: Eight @entity1 (38.0%) showed excellent improvement (>75-100%), one @entity1 (4.8%) had good (>50-75%), two @entity1 (9.6%) had fair (>25-50%), three @entity1 (14.3%) had minimal (0-25%), and seven @entity1 (33.3%) had no improvement. The snoring or stridor completely disappeared in two subjects, although there was no apparent decrease in @entity600 size. Moreover, all three @entity1 with @entity75 displayed a positive response to @entity7855 treatment, followed by mixed type (9/12, 75%). Only two out of six @entity1 with @entity75 had minimal clearance. Only four @entity1 showed transient mild @entity294 , there was no other adverse effect in this series.

Efficacy and safety of oral XXXX in treatment of pediatric head and neck @entity600 .

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity75 :: ('MESH:D001927', 'Disease') :: ['microcystic lesions', 'macrocystic lesion', 'macrocystic lesions'] @entity294 :: ('MESH:D003967', 'Disease') :: ['diarrhea'] @entity600 :: ('MESH:D000014', 'Disease') :: ['LMs', 'lymphatic malformations'] @entity7855 :: ('MESH:C101426', 'Chemical') :: ['sildenafil', 'sildenafil citrate']
@entity7855 :: (MESH:C101426,Chemical) :: ['sildenafil']
