UNASSIGNED: Background Cocaine is a highly abused substance in United States with almost 70 % of cocaine adulterated with levamisole. It is known to cause @entity1333 involving multiple organs due to its direct toxic effect and by the contribution of levamisole or a combined effect of both. Case Report A 51-year-old @entity1 complained of @entity158 @entity1910 in her hands and lower extremities that started few hours after smoking cocaine and progressed to blistering dark lesions in her lower extremities. She denied any other systemic complaints. Although she has been smoking cocaine for more than 35 years, these @entity272 started only 4 years ago. Examination revealed @entity925 in the hand and @entity925 with @entity548 in the legs. Initially, she had only a significantly positive atypical p-ANCA and later developed combined positivity of both @entity3335 ( @entity3335 ) and Anti-proteinase-3( @entity7134 ) antibodies with a p-ANCA pattern on immunofluorescence. We report a unique case of cocaine (likely contaminated with levamisole)-induced delayed recurrent @entity1333 with varying vasculitic antibodies over the years. Conclusions This case highlights the fact that @entity1 can develop cocaine-related @entity1333 after many years of uneventful abuse. Cocaine, with its adulterant levamisole, has the propensity to trigger diverse immunological reactions, which is evident by the varying antibody profile seen in the same @entity1 over time.

Cocaine-Induced Delayed Recurrent XXXX : A 4-Year Follow-Up.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'patient'] @entity3335 :: ('4353', 'Gene') :: ['MPO', 'Myeloperoxidase'] @entity1910 :: ('MESH:D005076', 'Disease') :: ['erythematous rash'] @entity1333 :: ('MESH:D014657', 'Disease') :: ['vasculitis'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhagic bulla'] @entity158 :: ('MESH:D010146', 'Disease') :: ['painful'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin eruptions'] @entity7134 :: ('5657', 'Gene') :: ['PR3'] @entity925 :: ('MESH:D063806', 'Disease') :: ['tender retiform purpura']
@entity1333 :: (MESH:D014657,Disease) :: ['Vasculitis']
