STUDY OBJECTIVES: To investigate the relationship between direct or environmental @entity286 smoke (ETS) exposure and both hospital-based care (HBC) and quality of life (QOL) among subjects with @entity565 . STUDY DESIGN: We report baseline cross-sectional data on 619 subjects with @entity565 , including direct or ETS exposure and QOL, and prospective longitudinal data on HBC using administrative databases for 30 months following baseline evaluation. SETTING AND @entity1 : @entity1 were health maintenance organization members with physician-diagnosed @entity565 involved in a longitudinal study of risk factors for hospital-based @entity565 care. MEASUREMENTS: Demographic characteristics and QOL were assessed with administered questionnaires, including the Marks Asthma Quality-of-Life (AQLQ) and SF-36 questionnaires. HBC was defined as episodes per @entity1 -year of hospital-based @entity565 care, which included emergency department and urgency care visits, and hospitalizations for @entity565 . RESULTS: Current smokers reported significantly worse QOL than never-smokers in two of five domains of the AQLQ (p < 0.05). Subjects with ETS exposure also reported significantly worse QOL than those without ETS exposure in two domains (p < 0.05). On the SF-36, current smokers reported significantly worse QOL than never-smokers in five of nine domains (p < 0.05). Subjects with ETS exposure reported significantly worse QOL than those without ETS exposure in three domains (p < 0.05). Current smokers used significantly more hospital-based @entity565 care than never-smokers (adjusted relative risk [RR], 1.40; 95% confidence interval [CI], 1.01 to 1.95) while ex-smokers did not exhibit increased risk compared with nonsmokers (adjusted RR, 0.94; 95% CI, 0.7 to 1.3). Also, subjects with ETS exposure used significantly more hospital-based @entity565 care than those without ETS exposure (RR, 2.34; 95% CI, 1.80 to 3.05). CONCLUSIONS: Direct or environmental @entity286 exposure prospectively predicted increased health-care utilization for @entity565 and reduced QOL in @entity1 with @entity565 . These findings add to our existing knowledge of the detrimental effects of @entity286 smoke and are of relevance specifically to @entity1 with @entity565 .

Associations of smoking with hospital-based care and quality of life in XXXX with obstructive airway disease.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS', 'Participants', 'person'] @entity286 :: ('4097', 'Species') :: ['tobacco'] @entity565 :: ('MESH:D001249', 'Disease') :: ['asthma']
@entity1 :: (9606,Species) :: ['patients']
