PURPOSE: To provide guidelines for safe implantation of @entity726 ( @entity726 ) in small and pediatric eyes to avoid contact between the optic nerve (ON) and the posterior edge of the @entity26585 plate. METHODS: We developed a formula for calculating limbus-to-ON distance to estimate the available "real estate" for @entity26585 placement in small eyes. The formula was validated using eyes of pediatric decedents undergoing clinical autopsy, with @entity3656 ( @entity3656 ) of 15-24  mm. For each autopsy eye, we measured @entity3656 , anterior chamber depth, corneal diameter, and limbus-to-ON distances for the four eye quadrants. The main outcome measure was the degree of agreement between measured and calculated limbus-to-ON distances. RESULTS: A total of 15 autopsy eyes were divided into derivation (n  =  10) and validation (n  =  5) groups. A formula was derived to estimate superotemporal limbus-to-ON distance (DST) using @entity3656 and corneal diameter data. Linear regression showed excellent correlation between the measured DST and @entity3656 (R(2)  =  0.98). There was excellent agreement between measured and calculated limbus-to-ON values for all four eye quadrants (R(2) range, 0.92-0.98). CONCLUSIONS: Our formula accurately predicts limbus-to-ON distances across a wide range of clinically relevant ALs. Based on this information, @entity26585 surgery in small eyes can be adjusted by positioning the @entity26585 closer to the limbus or by trimming the posterior edge of the @entity26585 plate. To our knowledge, this is the first set of guidelines developed to promote safe implantation of @entity726 in small eyes.

Staying away from the optic nerve: a formula for modifying XXXX drainage device surgery in pediatric and other small eyes.

@entity3656 :: ('MESH:D007870', 'Disease') :: ['AL', 'axial lengths'] @entity26585 :: ('OMIM:166260', 'Disease') :: ['GDD'] @entity726 :: ('MESH:D005901', 'Disease') :: ['GDDs', 'glaucoma drainage devices']
@entity726 :: (MESH:D005901,Disease) :: ['glaucoma']
