Obesity has reached epidemic proportions in the USA. Consequently, there is an increasing number of @entity28 @entity6 @entity1 who would otherwise be appropriate candidates for pancreas transplantation (PTx). This is a retrospective study of all PTx performed at Indiana University between 2003 and 2009 (n = 308) comparing recipients with body mass index (BMI) < 25, 25-29.9, and >= 30 kg/m(2) Data included recipient and donor demographics, seven and 90-d @entity393 , one-yr pancreas, kidney (for SPK only) and @entity1 survival, causes of @entity393 and @entity204 , peak amylase and lipase, length of stay, readmissions, complications, HbA1C, and @entity2690 . Of the 308 PTx, 100 (32%) were overweight and 42 (14%) were @entity28 . Obese recipients were older and more likely to be @entity1 . Donor demographics were similar. There was no difference in seven-d or 90-d @entity393 , one-yr pancreas, kidney or @entity1 survival, cause of @entity393 or @entity204 , 30-d peak amylase or lipase, HbA1C, or @entity2690 . The incidence of post-transplant technical, immunological and infectious complications was similar except for an increased incidence of @entity2803 in the @entity28 group. Two recipients returned to insulin therapy despite normal @entity2690 levels. Although technically challenging, PTx can be successful in select @entity28 recipients with similar results compared to normal BMI recipients.

Growth of a nation part II: impact of recipient XXXX on whole-organ pancreas transplantation.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'men'] @entity2803 :: ('MESH:D003586', 'Disease') :: ['cytomegalovirus infection'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity28 :: ('MESH:D009765', 'Disease') :: ['obese'] @entity2690 :: ('3630', 'Gene') :: ['c-peptide', 'C-peptide'] @entity393 :: ('MESH:D034381', 'Disease') :: ['graft loss'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity28 :: (MESH:D009765,Disease) :: ['obesity']
