BACKGROUND: @entity378 has increased in parallel with the acquired @entity465 and the use of immunosuppressive therapy, and the growing incidence of @entity1907 , especially with intestinal involvement, reflects this trend. However, the duration of anti-tuberculous therapy has not been clarified in intestinal @entity378 . AIM: To compare the efficacy of different treatment durations in @entity1964 in terms of response and recurrence rates. METHODS: Forty @entity1 with @entity1964 were randomized prospectively: 22 @entity1 into a 9-month and 18 into a 15-month group. Diagnosis was made either by colonoscopic findings of discrete @entity1066 and histopathological findings of caseating @entity738 and/or acid-fast bacilli, or by clinical improvement after therapeutic trial. @entity1 were followed up with colonoscopy every other month until complete response or treatment completion, and then every 6 months for 1 year and annually. Complete response was defined as a resolution of symptoms and active @entity378 by colonoscopy. RESULTS: Complete response was obtained in all @entity1 in both groups. Two @entity1 in the 9-month group and one in the 15-month group underwent operation due to @entity1321 , respectively. No recurrence of active intestinal @entity378 occurred during the follow-up period in either group. CONCLUSIONS: @entity1964 can be managed by 9-month chemotherapy without disease recurrence. Further investigations are needed in immunocompromised @entity1 .

Is a 9-month treatment sufficient in XXXX ? A prospective, randomized, single-centre study.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity738 :: ('MESH:D006099', 'Disease') :: ['granuloma'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcers'] @entity465 :: ('MESH:D007153', 'Disease') :: ['immunodeficiency syndrome epidemic'] @entity1321 :: ('MESH:D007415', 'Disease') :: ['intestinal obstruction and perianal fistula'] @entity378 :: ('MESH:D014376', 'Disease') :: ['Tuberculosis', 'tuberculosis'] @entity1964 :: ('MESH:D004760', 'Disease') :: ['tuberculous enterocolitis', 'Tuberculous enterocolitis'] @entity1907 :: ('MESH:D014397', 'Disease') :: ['extra-pulmonary tuberculosis']
@entity1964 :: (MESH:D004760,Disease) :: ['tuberculous enterocolitis']
