@entity712 is a very common disease with ageing of the population and represents the leading cause of admission to hospital. The consequences of ageing, the frequency of @entity299 and @entity101 predispose to the development of @entity712 . Ageing promotes arterial, aortic and @entity299 , resulting in an increase of cardiac work, @entity1283 and progressive alteration of ventricular function. The elderly heart has a reduced compliance, and loses its preload reserve and its chronotropic reserve. It adapts poorly to effort, @entity943 and loss of atrial systole. @entity712 can be atypical with @entity51 . Radiological examination, and especially echocardiography, are essential. There is often a very predominant alteration of diastolic function (abnormalities of relaxation and compliance). Treatment is made difficult by the presence of multi-organ disease, which reduces the safety margin of digitalis alkaloids, diuretics and @entity1289 inhibitors. Blood digoxin, @entity1011 and @entity972 levels must be regularly monitored. Revascularization techniques should not be abandoned and aortic valve surgery, in particular, gives good results when it is not performed too late. @entity1289 inhibitors and vasodilators are generally well tolerated.

[ XXXX with normal systolic function. Physiopathology and therapeutic implications].

@entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity712 :: ('MESH:D006333', 'Disease') :: ['Heart failure', 'heart failure'] @entity1289 :: ('1636', 'Gene') :: ['ACE'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['myocardial hypertrophy'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurological and pulmonary or gastrointestinal signs'] @entity299 :: ('MESH:D006331', 'Disease') :: ['ischaemic heart disease', 'cardiac remodelling'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity943 :: ('MESH:D001145', 'Disease') :: ['arrhythmias']
@entity299 :: (MESH:D006331,Disease) :: ['Cardiac insufficiency']
