The @entity339 ( @entity339 ) in @entity48166 has been infrequently analyzed from a pathological standpoint. In this study, we have attempted to elucidate the pathology of @entity339 in this interesting syndrome in 44 autopsied cases of combined non-primum @entity118 ( @entity118 ) and @entity339 collected over 16 years. The @entity1 were divided into 3 groups: Group 1: non-primum @entity118 with clinically diagnosed @entity4794 ( @entity4794 )  regurgitation, Group 2: non-primum @entity118 with clinically diagnosed @entity339 ( @entity339 ) and, Group 3: non-primum @entity118 with no clinically evident @entity339 , but with mitral valve pathology diagnosed at autopsy. All 44 @entity1 were symptomatic. There were 26 males (59%). The ages ranged from 13 to 73 years. A history of @entity4789 was available in 2 @entity1 while 16 @entity1 had undergone surgery or intervention for the disease. Of the 18 @entity1 in Group 1, six @entity1 did not show histological features of @entity6331 , although they shared similar gross morphological features. Furthermore, the @entity339 in 12 of 19 @entity1 in Group 2 was non-rheumatic. Also, only one @entity1 had histological evidence of rheumatic activity among seven cases in Group 3. In spite of a high rheumatic load at our center, more than half (54.5%) of @entity1 had "non-rheumatic" mitral valve pathology. Thus, the mitral @entity340 commonly labeled 'rheumatic' in @entity48166 are not always so. The distinction into rheumatic and non-rheumatic @entity339 in non-primum @entity118 has to be made on the basis of microscopic criteria.

XXXX : Is the mitral pathology always rheumatic?

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity4789 :: ('MESH:D012213', 'Disease') :: ['rheumatic fever'] @entity6331 :: ('MESH:D012214', 'Disease') :: ['rheumatic heart disease'] @entity339 :: ('MESH:D008944', 'Disease') :: ['mitral valve disease', 'mitral regurgitation', 'MVD', 'MR'] @entity48166 :: ('MESH:D008185', 'Disease') :: ["Lutembacher's syndrome"] @entity4794 :: ('MESH:D008946', 'Disease') :: ['MS', 'mitral stenosis'] @entity118 :: ('MESH:D006344', 'Disease') :: ['atrial septal defect', 'ASD'] @entity340 :: ('MESH:D006349', 'Disease') :: ['valvular lesions']
@entity48166 :: (MESH:D008185,Disease) :: ['Lutembacher's syndrome']
