UNASSIGNED: @entity302 with @entity1654 (BECTS) is often associated with neural circuit dysfunction, particularly during the transient active state characterized by @entity302 ( @entity302 ). Little is known, however, about the functional neural circuit abnormalities in BECTS without @entity302 , or if such abnormalities could be used to differentiate BECTS @entity1 without @entity302 from healthy controls (HCs) for early diagnosis. To this end, we conducted resting-state functional magnetic resonance imaging (RS-fMRI) and simultaneous Electroencephalogram (EEG) in @entity1 with BECTS (n   =   43) and age-matched HC (n   =   28). The simultaneous EEG recordings distinguished BECTS with @entity302 (n   =   20) from without @entity302 (n   =   23). Intrinsic brain activity was measured in all three groups using the amplitude of low frequency fluctuation at rest. Compared to HC, BECTS @entity1 with @entity302 exhibited an intrinsic activity abnormality in the thalamus, suggesting that @entity9479 could contribute to IED emergence while @entity1 without @entity302 exhibited @entity2526 in middle frontal gyrus and superior parietal gyrus. Using multivariate pattern classification analysis, we were able to differentiate BECTS without @entity302 from HCs with 88.23% accuracy. BECTS without @entity302 transients can be distinguished from HC and BECTS with @entity302 by unique regional abnormalities in resting brain activity. Both @entity854 as reflected by @entity102 as reflected by RS-fMRI may contribute to BECTS development and expression. Intrinsic brain activity and multivariate pattern classification techniques are promising tools to diagnose and differentiate BECTS syndromes. Hum Brain Mapp, 2015.    2015 Wiley Periodicals, Inc.

Intrinsic brain activity as a diagnostic biomarker in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity102 :: ('MESH:D002908', 'Disease') :: ['IEDs and chronic abnormalities'] @entity2526 :: ('MESH:D025063', 'Disease') :: ['intrinsic activity abnormalities'] @entity9479 :: ('MESH:D013786', 'Disease') :: ['thalamic dysfunction'] @entity1654 :: ('MESH:D019305', 'Disease') :: ['centrotemporal spikes'] @entity854 :: ('MESH:D018376', 'Disease') :: ['transient abnormalities'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epileptic', 'IEDs', 'interictal epileptiform discharges', 'Benign epilepsy']
@entity1654 :: (MESH:D019305,Disease) :: ['benign epilepsy with centrotemporal spikes']
