BACKGROUND: @entity3328 is a @entity1800 caused by 1 of the 3 strains of @entity9925 . The World Health Organization launched an eradication campaign in 1988. Although the number of cases of @entity3328 has @entity810 , eradication has not yet been achieved, and there are a substantial number of survivors of the disease. @entity3328 present a unique set of challenges to the anesthesiologist. The scientific literature regarding the anesthetic management of survivors of @entity3328 , however, is limited and primarily experiential in nature. Using a retrospective, matched cohort study, we sought to more precisely characterize the anesthetic implications of @entity3328 and to determine what risks, if any, may be present for @entity1 with a history of the disease. METHODS: Using the Mayo Clinic Life Sciences System Data Discovery and Query Builder, study subjects were identified as those with a history of @entity3328 who had undergone major surgery at Mayo Clinic Rochester between 2005 and 2009. For each case, 2 sex- and age-matched controls that underwent the same surgical procedure during the study period were randomly selected from a pool of possible controls. Medical records were manually interrogated with respect to demographic variables, comorbid conditions, operative and anesthetic course, and postoperative course. RESULTS: We analyzed 100 cases with 2:1 matched controls and found that the peri- and postoperative courses were very similar for both groups of @entity1 . @entity158 scores, postanesthesia care unit admission, length of postanesthesia care unit stay, intensive care unit admission, length of intensive care unit stay, and initial extubation location were not significantly different between the 2 groups. Looking at @entity358 in our primary outcome, there was no significant difference between the 2 groups (17% vs 14% for polio versus control, respectively; conditional logistic regression odds ratio = 1.5; 95% confidence interval, 0.7-3.3; P = 0.33). In addition, no difference was noted in those requiring a code or rapid response team intervention (4% vs 3% for polio versus control; P = 0.46) and the 30-day mortality rate was also not significantly different, with 2% of polio @entity1 dying compared with 3% of controls (P = 0.79). The analysis of the primary outcome was repeated for the subset of @entity1 with a history of @entity3328 who had persistent @entity51 preoperatively (n = 36) and their matched controls (n = 72). In this subset analysis, there were 4 (11%) polio @entity1 and 8 (11%) control @entity1 who experienced @entity358 (conditional logistic regression odds ratio = 1.00; 95% confidence interval, 0.27-3.72; P = 1.00). The percentage of @entity1 experiencing specific @entity358 of interest was similar between groups (postoperative mechanical ventilation: 6% vs 8% for polio and control @entity1 , respectively; prolonged mechanical ventilation: 0% vs 1%; reintubation: 8% vs 4%; @entity358 : 6% vs 6%; and aspiration: 0% vs 1%). CONCLUSIONS: This study suggests that @entity1 with a history of @entity3328 do not seem to have an increased risk of @entity358 in the perioperative period. However, an odds ratio as great as 3.3-fold may be present.

Anesthesia and XXXX : A Matched Cohort Study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3328 :: ('MESH:D011051', 'Disease') :: ['poliomyelitis', 'Survivors of poliomyelitis', 'Poliomyelitis', 'paralytic poliomyelitis'] @entity9925 :: ('138950', 'Species') :: ['poliovirus'] @entity51 :: ('MESH:D009461', 'Disease') :: ['neurologic deficits'] @entity1800 :: ('MESH:D014777', 'Disease') :: ['viral infectious disease'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary complications', 'pulmonary infection'] @entity810 :: ('MESH:D058186', 'Disease') :: ['drastically declined'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain']
@entity3328 :: (MESH:D011051,Disease) :: ['Poliomyelitis']
