We elucidated the mechanism and clinical significance of @entity308 in @entity1 with an @entity583 using first-pass, contrast-enhanced, myocardial perfusion magnetic resonance imaging (MRI). Forty-seven @entity1 with acute @entity583 underwent first-pass contrast-enhanced MR studies within 2-6 days postinfarction. @entity1 were followed-up for a minimum of 1 year after @entity1188 (range, 12-32 months). Total perfusion deficit scores derived qualitatively from MRIs were compared in @entity1 with (group 1, n = 30) and without (group 2, n = 17) ST @entity308 precordially. Perfusion remote from the @entity1188 zone was also compared. The combined end points of adverse clinical events and/or the need for further intervention were assessed for each group. Total perfusion deficit scores were significantly higher in group 1 than group 2 (medians 9.7 versus 4.5, p < 0.005). Posterolateral basal extension of hypoperfusion was greater in group 1 versus group 2 (1.23 versus 0.42, p < 0.02), with no evidence of remote anterior perfusion abnormalities. There were more @entity1 with an adverse clinical end point in group 1 versus group 2 (18 versus 1, p < 0.01). Furthermore, in @entity1 with ST @entity308 (group 1), there was a significant increase in number of adverse clinical end points in @entity1 with a global deficit score > 15 versus 0-5 (7/7 versus 1/7, p < 0.01). MRI shows that @entity308 in @entity583 is a marker for a larger global perfusion abnormality with posterolateral basal extension and an increase in adverse clinical end points. Furthermore, the magnitude of the perfusion deficit correlates with an increase in the number of adverse clinical end points, highlighting the potential of MRI perfusion studies as a research and clinical tool in @entity583 .

Mechanism and clinical significance of XXXX in @entity583 : evaluation by contrast-enhanced dynamic myocardial perfusion magnetic resonance imaging.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'inferior myocardial infarction'] @entity308 :: ('MESH:D003866', 'Disease') :: ['precordial ST depression', 'depression'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct']
@entity308 :: (MESH:D003866,Disease) :: ['precordial ST depression']
