OBJECTIVE: To identify causative bacteria from cerebrospinal fluid (CSF) of @entity1 with @entity693 and analyse various clinical and laboratory parameters. METHODS: Over a 20 month period, September 1994 to April 1996, one hundred episodes of acute @entity4008 in @entity1 aged 1 month-12 years were studied in a tertiary urban hospital in South India. Organisms were isolated from the cerebrospinal fluid (CSF) in 35% of cases. Among @entity1 and @entity1 , the two major pathogens were @entity327 (17%) and @entity2260 (12%). RESULTS: The illness at presentation was mild in 13% and severe in 36% of cases. The association of subdural effusion in @entity1 with Salmonella Gp B @entity693 merits attention. The overall case fatality rate was 25%. @entity2260 had a higher case fatality rate than Salmonella Gp B and @entity327 (50% vs 17% vs 12%). All the three @entity1 below 3 months of age with @entity2260 @entity693 died. On analysis of selected clinical and laboratory features by discriminant analysis, CSF culture was the significant (P = 0.02) variable in relation to outcome. In @entity2506 , CSF WBC count was a highly significant variable in relation to outcome (Wilk's Lambda 0.15, F = 24.64, P = 0.0002). CONCLUSION: Prevention of infections due to @entity327 and @entity2260 should be given higher priority.

Childhood XXXX in Pondicherry, South India.

@entity1 :: ('9606', 'Species') :: ['children', 'infants'] @entity4008 :: ('MESH:D016920', 'Disease') :: ['bacterial meningitis'] @entity327 :: ('727', 'Species') :: ['H. influenzae'] @entity2260 :: ('2104', 'Species') :: ['S. pneumoniae'] @entity2506 :: ('MESH:D008586', 'Disease') :: ['pneumococcal meningitis'] @entity693 :: ('MESH:D008581', 'Disease') :: ['meningitis']
@entity4008 :: (MESH:D016920,Disease) :: ['bacterial meningitis']
