PURPOSE: To investigate the use of an expanded @entity736 -coated @entity5648 stent-graft in @entity1 with failing hemodialysis access circuits and compare grafts with and without a heparin-coated surface. MATERIALS AND METHODS: A single-institution retrospective review of 16 @entity1 (average age, 55 years; seven @entity1 ) treated for hemodialysis access circuit stenoses was performed. @entity1 had a prosthetic arteriovenous (AV) graft (n = 10) or autogenous AV @entity292 (n = 6), all with clinically relevant access stenoses that were refractory to angioplasty alone; 10 @entity1 also had access circuit @entity715 at the time of treatment. Stents were placed in the basilic (n = 4), brachial (n = 7), cephalic (n = 4), and femoral (n = 1) veins. Study endpoints included primary treatment area patency, primary circuit patency, primary assisted circuit patency, and secondary circuit patency, followed to a maximum of 6 months. RESULTS: Primary treatment area patency rates at 30 days and 180 days were 75% and 31%, respectively. Secondary patency rates at the same time points were 88% and 68%, respectively. Mean primary treatment area patency was 93 days. @entity715 was a major cause of failure, occurring in seven of 11 cases of primary treatment area patency loss. Subgroup analysis demonstrated that the heparin-coated configuration (n = 7) showed a 6-month primary patency rate of 57%, compared with 11% for the stent-grafts without heparin bonding (n = 9; P = .06). CONCLUSIONS: Overall, the majority of deployed stent-grafts lost primary patency within 6 months, with @entity715 a major cause of failure. However, the addition of a heparin-coated surface appeared to improve results in these otherwise treatment-refractory access circuits.

Evaluation of expanded XXXX -covered stents for the treatment of venous outflow stenosis in hemodialysis access grafts.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'men'] @entity292 :: ('MESH:D005402', 'Disease') :: ['fistula'] @entity736 :: ('CHEBI:53251', 'Chemical') :: ['polytetrafluoroethylene'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis', 'Thrombosis'] @entity5648 :: ('MESH:C013616', 'Chemical') :: ['nitinol']
@entity736 :: (CHEBI:53251,Chemical) :: ['polytetrafluoroethylene']
