OBJECTIVE: Local @entity479 injection to the stricture region after internal urethrotomy (IU) is a promising technique to avoid the recurrence, although the effectiveness and safety of this technique is still controversial. We aimed to determine the efficacy and safety of local @entity230 as applied with the IU procedure. MATERIAL-METHOD: A total of 83 @entity1 data with @entity3832 in @entity1 were examined retrospectively. @entity1 classified in two groups who had @entity479 injection with internal urethrotomy or not. Metil @entity617 40 mg was injected with transurethral injection needle in the stricture region at the 5, 7 and 12 o'clock sites at the same session with internal urethrotomy. Procedure was considered successful if @entity1 did not report any voiding difficulty and maximum flow rate > 15 mL/second for a voided volume of at least 150 mL after removal of the catheter. @entity1 's age, time to recurrence, previous recurrences were evaluated. RESULTS: The mean age was 56.4 (18-83) years. Of those @entity1 33/83 had recurrent @entity850 . Nineteen out of these 33 recurrent @entity850 @entity1 were treated with local @entity479 injection and 14/33 had no injection. Only two @entity1 of the @entity479 treated group had recurrence. Despite that 12 @entity1 had recurrence in the @entity479 non-treated group. Also the primary @entity850 @entity1 showed no recurrence at the @entity479 + IU group. CONCLUSIONS: The use of local @entity230 with IU seems to decrease the high stricture recurrence rate following IU. When local @entity230 were administered with complementary intention, the disease control outcomes are encouraging. Further robust comparative effectiveness studies are now required.

The effectiveness of local XXXX injection after internal urethrotomy to avoid recurrence.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient', 'Patient', 'men'] @entity3832 :: ('MESH:D014525', 'Disease') :: ['urethral stricture'] @entity230 :: ('MESH:D013256', 'Chemical') :: ['steroids'] @entity850 :: ('MESH:D003251', 'Disease') :: ['stenosis'] @entity617 :: ('MESH:D011239', 'Chemical') :: ['prednisolone'] @entity479 :: ('D013256', 'Chemical') :: ['steroid']
@entity479 :: (D013256,Chemical) :: ['steroid']
