UNASSIGNED: In this pilot study, we compared the @entity1188 and @entity4 size in acute @entity583 ( @entity583 ) @entity1 treated by @entity7976 with those treated by @entity1507 , using cardiac magnetic resonance (CMR) imaging. Fifty-two acute @entity583 @entity1 who underwent emergency percutaneous coronary intervention (PCI) were enrolled, and were assigned to receive @entity7976 or @entity1507 at random just before reperfusion. For the assessment of @entity1188 and @entity4 areas, short-axis delayed enhancement (DE) and T2-weight (T2w) CMR images were acquired 6.1      2.4  days after the onset of @entity583 . A significant correlation was observed between the peak @entity1011 kinase (CK) level and the @entity1188 size on DE CMR (r  =  0.62, p  <  0.05), as well as the @entity4 size on T2w CMR (r  =  0.70, p  <  0.05) in @entity1 treated by @entity7976 (28 @entity1 ). A similar correlation was seen between the peak CK level and the @entity1188 size on DE CMR (r  =  0.84, p  <  0.05), as well as the @entity4 size on T2w CMR (r  =  0.84, p  <  0.05) in @entity1 treated by @entity1507 (24 @entity1 ). The maximum CK level was significantly lower in @entity1 treated by @entity7976 rather than @entity1507 (1991      1402, 2785      2121  IU/L, respectively, p  =  0.03). Both the @entity4 size on T2w CMR and the @entity1188 size on DE CMR were significantly smaller in @entity1 treated by @entity7976 rather than @entity1507 (17.7      9.9, 21.9      13.7  %; p  =  0.03, 10.3      6.0, 12.7      6.9  %, p  =  0.03, respectively). The presence and amount of @entity3885 were significantly smaller in @entity1 treated by @entity7976 rather than @entity1507 (39.2, 64.7  %; p  =  0.03; 2.2      1.3, 3.4      1.5  cm(2); p  =  0.02, respectively). Using CMR imaging, we demonstrated that the complementary use of intravenously and intracoronary administered @entity7976 during PCI favorably acts more on the damaged myocardium after @entity583 than @entity1507 . We need a further powered prospective study on the use of @entity7976 .

Impacts of @entity7976 on @entity1188 in comparison with XXXX : assessed by cardiac magnetic resonance imaging.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity1507 :: ('CHEBI:48107', 'Chemical') :: ['nitrate'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['microvascular obstruction'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI'] @entity7976 :: ('MESH:D020108', 'Chemical') :: ['nicorandil']
@entity1507 :: (CHEBI:48107,Chemical) :: ['nitrate']
