The allergenicity of @entity7227 ( @entity10155 ) is related to oxidative processes on and in the skin. @entity1 with stronger reactions to @entity10155 are significantly more likely to have a clear history of reacting to normal consumer hair dye. Those with stronger reactions are much less likely to be still dyeing their hair. Individuals allergic to @entity10155 have a significant frequency of simultaneous sensitivity to chemically related clothing dyes. A 24-hour test application of hair dye, which has been proposed as a self-screen, does not reliably predict all individuals allergic to @entity10155 . Duration studies have proven that exposures of 5 to 30 minutes, the period used for hair dyeing, are sufficient to elicit reactions. A significant rise in the frequency of @entity10155 @entity566 was observed over 7 years among our patch test population. Active sensitization from standard @entity10155 patch testing is not common. Immunologic findings relating to @entity10155 can correctly predict that if hair dyes are commonly used there will be a significant prevalence of @entity566 to @entity10155 among the normal adult population and that some clinical reactions will be severe. To protect the public from @entity566 to chemicals in consumer products, immunologic and epidemiologic data should both be used by regulatory authorities.

Clinical and experimental aspects of allergic contact dermatitis to XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients'] @entity7227 :: ('MESH:C029728', 'Chemical') :: ['para-phenylenediamine'] @entity566 :: ('MESH:D006967', 'Disease') :: ['allergy'] @entity10155 :: ('MESH:D014373', 'Chemical') :: ['PPD']
@entity7227 :: (MESH:C029728,Chemical) :: ['para-phenylenediamine']
