BACKGROUND AND OBJECTIVES: Few reports have described the combined use of biologic and imaging techniques in the diagnosis of lymph node @entity3 . We prospectively evaluated lymph node @entity3 diagnosed by biologic and imaging means in @entity1 with @entity418 . METHODS: Preoperative ultrasound and endoscopic ultrasound (EUS) examination were performed in 80 @entity1 . Biopsy specimens were immunohistochemically examined using @entity4910 ( @entity4910 ) and @entity7620 ( @entity7620 ) antibodies, and @entity5 were classified into three grades. RESULTS: The sensitivity, specificity, and accuracy values of ultrasound examination were 88.2, 58.6, and 77.5%, respectively. The incidence of nodal involvement was 0% (0/10) in @entity1 with grade 1 @entity5 , 57.1% (16/28) in those with grade 2 @entity5 , and 83.3% (35/42) in those with grade 3 @entity5 . Of the 57 @entity1 with lymph node @entity3 determined sonographically, 50 had grade 2 or 3 @entity5 that were histologically confirmed. The remaining seven @entity1 with grade 1 @entity5 did not have involved nodes. Of the 23 @entity1 without lymph node @entity3 according to ultrasound examination, the incidence of lymph node @entity3 in @entity1 with grade 1, 2, and 3 @entity5 was 0, 16.7, and 50.0%, respectively. CONCLUSIONS: When used together, imaging and molecular procedures may offer improved identification of lymph node @entity3 in @entity1 with @entity957 of the esophagus.

Biologic and imaging diagnosis of lymph node @entity3 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma'] @entity4910 :: ('595', 'Gene') :: ['cyclin D1', 'CD1'] @entity7620 :: ('1828', 'Gene') :: ['DG1', 'desmoglein 1'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal carcinoma'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastasis']
@entity418 :: (MESH:D004938,Disease) :: ['esophageal carcinoma']
