BACKGROUND: @entity1 with a history of a false-positive mammogram result may be at increased risk of developing subsequent @entity0 . METHODS: Using 1994 to 2009 @entity0 Surveillance Consortium data, we included @entity1 ages 40 to 74 years with a screening mammogram that resulted in a false-positive with recommendation for additional imaging, false-positive with recommendation for biopsy, or true-negative with no @entity5 within one year following the examination. We used partly conditional Cox proportional hazards survival models to assess the association between a false-positive mammogram result and subsequent @entity0 , adjusting for potential confounders. Adjusted survival curves stratified by breast density and false-positive result were used to evaluate changes in risk over time. RESULTS: During 12,022,560 @entity1 -years of follow-up, 48,735 @entity5 were diagnosed. Compared with @entity1 with a true-negative examination, @entity1 with a false-positive with additional imaging recommendation had increased risk of developing @entity0 [adjusted HR (aHR) = 1.39; 95% confidence interval (CI), 1.35-1.44] as did @entity1 with a false-positive with a biopsy recommendation (aHR = 1.76; 95% CI,1.65-1.88). Results stratifying by breast density were similar to overall results except among @entity1 with almost entirely fatty breasts in which aHRs were similar for both the false-positive groups. @entity1 with a false-positive result had persistently increased risk of developing @entity0 10 years after the false-positive examination. CONCLUSION/IMPACT: @entity1 with a history of a false-positive screening mammogram or biopsy recommendation were at increased risk of developing @entity0 for at least a decade, suggesting that prior false-positive screening may be useful in risk prediction models. Cancer Epidemiol Biomarkers Prev; 24(12); 1-8.   2015 AACR.

Increased Risk of Developing XXXX after a False-Positive Screening Mammogram.

@entity1 :: ('9606', 'Species') :: ['women', 'Women', 'person'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'cancer'] @entity0 :: ('MESH:D001943', 'Disease') :: ['Breast Cancer', 'breast cancer']
@entity0 :: (MESH:D001943,Disease) :: ['Breast Cancer']
