PURPOSE: To evaluate the effectiveness of intraarterial @entity3303 in controlling @entity158 after uterine artery embolization (UAE). MATERIALS AND METHODS: In this double-blind prospective study, @entity1 undergoing UAE received preservative-free 1% @entity3303 or saline solution (control) in the uterine arteries before embolization. Postprocedural @entity158 was managed with @entity1 -controlled intravenous @entity1286 . Attempted doses, number of doses received, total @entity1286 dose, and maximum @entity158 numeric rating scale (NRS) score during the postprocedural hospitalization were recorded and compared. Three-month follow-up magnetic resonance (MR) imaging and symptomatic questionnaires were collected and compared. RESULTS: Ten @entity1 received @entity3303 and eight @entity1 received placebo. Moderate to severe @entity2553 was noted in seven @entity1 after @entity3303 injection, whereas no @entity2553 was noted in the placebo group (P =.004). @entity1 in the @entity3303 group had lower NRS @entity158 scores than those in the placebo group (P =.012), whereas there was no difference in @entity1286 requirement between treated @entity1 and control subjects. The study was terminated after 18 @entity1 were treated as a result of unexpected @entity2553 . CONCLUSIONS: Intraarterial 1% @entity3303 is associated with moderate to severe @entity2553 . @entity3303 significantly lowers subjective @entity158 , but there is no difference in analgesic requirements. The routine use of intraarterial @entity3303 is not recommended for @entity158 control until the long-term effects of @entity2553 on outcome is known.

Intraarterial @entity3303 for XXXX control after uterine artery embolization for leiomyomata.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity3303 :: ('MESH:D008012', 'Chemical') :: ['lidocaine', 'Lidocaine'] @entity1286 :: ('MESH:D009020', 'Chemical') :: ['morphine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity2553 :: ('MESH:D020301', 'Disease') :: ['vasospasm']
@entity158 :: (MESH:D010146,Disease) :: ['pain']
