Objective. To quantify the effectiveness of nasal expiratory positive airway pressure (nasal EPAP) devices or Provent as treatment for @entity27 ( @entity27 ). Methods. PubMed and six other databases were searched through November 15, 2015, without language limitations. Results. Eighteen studies (920 @entity1 ) were included. Pre- and post-nasal EPAP means    standard deviations (M    SD) for @entity27 ( @entity27 ) in 345 @entity1 decreased from 27.32    22.24 to 12.78    16.89 events/hr (relative reduction = 53.2%). Random effects modeling mean difference (MD) was -14.78 events/hr [95% CI -19.12, -10.45], p value < 0.00001. @entity26 desaturation index (ODI) in 247 @entity1 decreased from 21.2    19.3 to 12.4    14.1 events/hr (relative reduction = 41.5%, p value < 0.00001). Lowest @entity26 saturation (LSAT) M    SD improved in 146 @entity1 from 83.2    6.8% to 86.2    11.1%, MD 3 @entity26 saturation points [95% CI 0.57, 5.63]. Epworth Sleepiness Scale (ESS) M    SD improved (359 @entity1 ) from 9.9    5.3 to 7.4    5.0, @entity1605 .5 [95% CI -3.2, -1.8], p value < 0.0001. Conclusion. Nasal EPAP (Provent) reduced @entity27 by 53.2%, ODI by 41.5% and improved LSAT by 3 @entity26 saturation points. Generally, there were no clear characteristics (demographic factors, medical history, and/or physical exam finding) that predicted favorable response to these devices. However, limited evidence suggests that high nasal resistance could be associated with treatment failure. Additional studies are needed to identify demographic and polysomnographic characteristics that would predict therapeutic success with nasal EPAP (Provent).

Nasal Expiratory Positive Airway Pressure Devices (Provent) for XXXX : A Systematic Review and Meta-Analysis.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen', 'Oxygen'] @entity1605 :: ('OMIM:217000', 'Disease') :: ['MD -2'] @entity27 :: ('MESH:D020181', 'Disease') :: ['apnea-hypopnea index', 'obstructive sleep apnea', 'OSA', 'AHI']
@entity27 :: (MESH:D020181,Disease) :: ['OSA']
