BACKGROUND: @entity1204 incidence rates are low in Asia and Africa and high in North America and Northern Europe. @entity5 is often the most common female @entity5 in developing countries, and @entity281 with @entity1082 ) is its main risk factor. However, other factors, such as occupational exposures may modify the HPV-related risk. We conducted an exploratory register-linkage study in Finland to assess the role of occupational exposures on incidence rates of @entity5 of the endometrium and cervix uteri. METHODS: Occupational risk factors for @entity1204 were explored in a 25-year follow-up of female workers born 1906-1945 (N = 413,877) identified through the Population Census of Finland of 1970. Job titles in census records were converted to exposures of 31 occupational agents through a job-exposure matrix. Poisson regression models estimated relative risks (RR) for each agent, standardized for birth cohort, follow-up period, and socio-economic status. For each agent, the product of level and probability of exposure was calculated and subdivided in three categories: zero, low, and medium/high. Adjustment at the job title level was done for the turnover rate ( @entity1204 ), mean parity, and age at first birth ( @entity1204 ). RESULTS: @entity1204 (2,833 cases) was associated with exposure to animal dust (RR 1.2, low level, 174 cases) and sedentary work (RR 1.3, high level, 145 cases). @entity5 (1,101 cases) was associated with exposure to aliphatic and alicyclic (RR 1.3, low level, 91 cases), aromatic (RR 1.2, low level, 318 cases; RR 1.4, high level, 41 cases), and chlorinated @entity7294 solvents (RR 1.3, low level, 50 cases), @entity3440 dust (RR 1.2, low level, 251 cases), and wood dust (RR 1.2, low level, 249 cases). CONCLUSIONS: This study suggests that occupational exposures may be associated with increased risk of @entity1204 .

Occupational exposures and XXXX of the endometrium and cervix uteri in Finland.

@entity1204 :: ('MESH:D016889', 'Disease') :: ['endometrial and cervical cancers', 'endometrial cancer', 'Endometrial cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancers', 'cancer', 'Cervical cancer'] @entity7294 :: ('CHEBI:24632', 'Chemical') :: ['hydrocarbon'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection'] @entity1082 :: ('10566', 'Species') :: ['human papillomavirus (HPV'] @entity3440 :: ('MESH:D012822', 'Chemical') :: ['silica']
@entity5 :: (MESH:D009369,Disease) :: ['cancers']
