@entity5 in the elderly show reduced growth potential; impaired angiogenesis may contribute to this phenomenon. Recent studies have suggested that the angiogenic potential of a @entity5 may be inferred by the vascularity measured in histological sections. The purpose of this study has been to determine whether vascularity is related to age, survival or other clinical parameters in resected @entity1149 ( @entity1149 ). A group of 88 consecutive @entity1 with a follow-up period of at least 5 years was selected. The group exhibited a wide age range (37-78 years) and similar survival characteristics to those of the general @entity1149 population. @entity5 sections were stained with a pan-endothelial antibody ( @entity2881 ) and vascularity was quantitated, without knowledge of the clinical details, by three methods: highest microvascular density; average microvascular density; and average microvascular volume. The results were analysed by non-parametric statistical tests. A correlation was found between all three methods of quantitation. Vascularity was not associated with age, sex, @entity5 type, stage, volume, size ( @entity1619 ) nodal status (TNM-N) or survival. However, survival time was generally longer for @entity1 with higher vascularity, reaching borderline significance (P = 0.06) for the average microvascular density values. Higher @entity5 volume (P = 0.02) and stage (P = 0.05) were associated with lower survival times. Using multivariate survival analysis, @entity5 volume was the only factor related to survival. We conclude that vascularity is not associated with age and has no significant prognostic value in @entity1149 .

Relationship between vascularity, age and survival in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1619 :: ('MESH:D015458', 'Disease') :: ['TNM-T'] @entity5 :: ('MESH:D009369', 'Disease') :: ['Tumour', 'Lung tumours', 'tumour'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small-cell lung cancer'] @entity2881 :: ('7450', 'Gene') :: ['vWF']
@entity1149 :: (MESH:D002289,Disease) :: ['non-small-cell lung cancer']
