BACKGROUND: It is unknown whether progression of familial @entity1000 differs from progression in the non-familial form. It has been suggested that @entity74 indicates a worse prognosis, and that this should be considered when planning the timing of heart transplantation. OBJECTIVE: To compare five year survival or time to heart transplantation in an unselected series of @entity1 with @entity384 who had been evaluated for familial v non- @entity74 through the echocardiographic investigation of first degree relatives. DESIGN: Medical records were reviewed and questionnaires were mailed to all @entity1 who had previously participated in a family based study of @entity384 . Information was gathered about survival, heart transplantation, and left ventricular ejection fraction (LVEF) measurements. Survival data were censored at the time of cardiac transplantation. RESULTS: Follow up data were obtained for 99 of 101 @entity1 (69 with non-familial and 30 with @entity74 ). Five year survival was 55% for non-familial and 51% for familial @entity1 (NS). The main predictor of mortality was an LVEF of < 30%. Familial status did not predict mortality. There was no significant difference in follow up LVEF values between the groups. CONCLUSIONS: Five year survival is not significantly different in the familial and non-familial forms of @entity384 .

Progression of familial and non-familial XXXX : long term follow up.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity384 :: ('MESH:D002311', 'Disease') :: ['dilated cardiomyopathy'] @entity1000 :: ('MESH:C536277', 'Disease') :: ['idiopathic dilated cardiomyopathy'] @entity74 :: ('MESH:D030342', 'Disease') :: ['familial disease']
@entity384 :: (MESH:D002311,Disease) :: ['dilated cardiomyopathy']
