OBJECTIVE: Assess to impact @entity2332 on @entity15032 , CPP, @entity428 and cerebral autoregulation. Material and methods. 14 @entity1 with @entity131 (GOS<9) underwent @entity2332 by Thermogard system within 32-35   C (Zoll, USA). @entity428 was measured intraparenchymal by Codman sensor. Cerebral autoregulation was estimated by correlation coefficient @entity10166 (Soft ICM Plus, Cambridge, UK). Temperature was measured in urinary bladder. There were selected five time periods: 1 - phase of initial state, 2 - phase of induction @entity2332 , 3 - phase of @entity2332 , 4 - phase of rewarming, 5 - phase after finishing @entity2332 . All data preset as Mediana (min; max). Stat analysis was perfomed using Soft Statistica 10.0. Results. Phase 1 lasted nearly 7 (2; 12) h, @entity15032 94 (81; 102), CPP - 73 (52; 87), @entity428 27 (16; 45) mm Hg, @entity10166 0,25 (-0,15; 0,7), temperature 38,2   C (37; 39,8). Phase 2: 5 (2; 12) h, @entity15032 95 (85; 114), CPP 80 (65; 96), @entity428 18 (10; 22) mm Hg, @entity10166 -0,055 (-0,15; 0,7), temperature 35,2   C (34,5; 35,5). Phase 3: 55 (20; 100) h, there were not significant changed @entity15032 , CPP, @entity10166 , @entity428 15 (10; 18) mm Hg, temperature was 33,5   C (32; 34,7). Phase 4: 17 (8; 24) h, @entity15032 90 (70; 100), CPP 77 (55; 85), @entity428 15 (9; 27) mm Hg and @entity10166 0,2 (-0,2; 0,32). Temperature 36,9   C (35,9; 38,5). Phase 5: 20 (6; 240) h, @entity15032 87(53; 110), CPP 72 (47; 107), @entity428 17 (10; 32) mm Hg and @entity10166 0,2 (-0,2; 0,6). Temperature 37,7   C (36,7; 39,0). Conclusion. @entity2332 is an effective method for correction of intracranial @entity101 . @entity2332 can use as a additional option of intensive care during refractory intracranial @entity101 . Rewarming phase is the most dangerous time on the re-development of intracranial @entity101 and disruption of autoregulation.

[The use of intravascular @entity2332 to correct intracranial XXXX in @entity1 with severe @entity131 ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity131 :: ('MESH:D001930', 'Disease') :: ['TBI'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity428 :: ('MESH:D019586', 'Disease') :: ['ICP'] @entity10166 :: ('57716', 'Gene') :: ['Prx'] @entity15032 :: ('26', 'Gene') :: ['ABP'] @entity2332 :: ('MESH:D007035', 'Disease') :: ['hypothermia', 'Hypothermia']
@entity101 :: (MESH:D006973,Disease) :: ['hypertension']
