OBJECTIVE: To test Antarth, a polyherbal phytomedicine, for its efficacy and safety in @entity1 with @entity571 ( @entity571 ) and compared with placebo. MATERIAL AND METHODS: A total of 90 male or female adult @entity1 who were diagnosed clinically and radiologically with @entity571 were recruited in the study. Antarth or placebo was given 2 capsules b.i.d. for 3 months and the @entity1 were assessed every month for its efficacy. @entity3522 was allowed to be taken as rescue medication. RESULTS: After 3 months of treatment, the reduction in severity of @entity158 on Visual Analog Scale (VAS) was more in Antarth group compared to placebo but the difference between the two groups was not significant. However, @entity158 during functioning of disabled joints while walking distance, squatting, sitting cross-legged and climbing steps were significantly reduced in Antarth group compared to placebo (P < 0.05). Reduction in consumption of rescue medication, @entity3522 , was more in Antarth than in placebo group. CONCLUSIONS: In @entity1 ' Global Assessment, @entity1 treated with Antarth were more satisfied than the ones treated with placebo. Observations were similar in Physicians' Global Assessment too. There were no adverse events in both the groups.

A double-blind, randomized, multicentric, placebo-controlled clinical trial of antarth, a phytomedicine, in the treatment of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity571 :: ('MESH:D010003', 'Disease') :: ['osteoarthritis', 'OA'] @entity3522 :: ('MESH:D004008', 'Chemical') :: ['Diclofenac sodium', 'diclofenac sodium']
@entity571 :: (MESH:D010003,Disease) :: ['osteoarthritis']
