BACKGROUND: @entity209 ( @entity209 ) has a robust concurrent association with @entity308 . A small, methodologically limited literature suggests that @entity209 and @entity308 are reciprocally related over time, an association that could contribute to their overlapping influences on morbidity and mortality in @entity65 , @entity6 , and @entity5 . PURPOSE: Using a refined approach to the measurement of @entity209 as a continuous latent variable comprising continuous components, this study tested the prospective associations between @entity209 and @entity308 . METHODS: This study of 1114 clergy included four annual assessments of @entity308 and @entity209 components. Standard methods were used to measure @entity209 risk factors, and the @entity1 Health Questionnaire-8 was used to assess @entity308 . We used confirmatory factor analysis to verify the structure of @entity209 and @entity308 and structural equation modeling to quantify the prospective relationships. RESULTS: The statistical models confirmed the validity of quantifying @entity209 as a continuous latent variable, replicated previous evidence of a concurrent association, and indicated a significant prospective association of @entity308 with subsequent @entity209 . Initial @entity209 was at most only weakly associated with subsequent @entity308 , and the former prospective effect was significantly larger. Associations of @entity308 and @entity209 were significant for both @entity1 and @entity1 , but somewhat stronger among @entity1 . CONCLUSIONS: Results support representation of @entity209 as a continuous latent variable. The association of @entity308 with later @entity209 suggests that interventions addressing these correlated risk factors may prove useful in preventive efforts.

Prospective Associations Between XXXX : the Spirited Life Study of Methodist Pastors in North Carolina.

@entity1 :: ('9606', 'Species') :: ['women', 'Patient', 'men'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depressive symptoms', 'depression', 'initial depressive symptoms'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetes'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity209 :: ('MESH:D008659', 'Disease') :: ['Metabolic syndrome', 'Met-S'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular disease']
@entity308 :: (MESH:D003866,Disease) :: ['Depressive Symptoms and the Metabolic Syndrome']
