BACKGROUND: While the use of @entity1289 ( @entity1289 ) inhibitors for @entity1 with @entity712 ( @entity712 ) is supported by the results of clinical trials and expert guidelines, national physician practices are unknown. METHODS: We analyzed 1529 physician office visits by @entity1 with @entity712 available from the 1989 through 1994 National Ambulatory Medical Care Surveys. We examined changes over time in the use of @entity1289 inhibitors and use of other medications for @entity712 . Potential clinical and nonclinical predictors of use of @entity1289 inhibitors were evaluated using multiple logistic regression. RESULTS: The prevalence of @entity712 increased from 0.9% of all office visits in 1989 to 1.1% in 1994. Use of @entity1289 inhibitors increased from 24% in visits by @entity1 with @entity712 in 1989 to 31% in 1994 (P = .02). From 1989 through 1994, use of @entity1289 inhibitors was more likely in visits to cardiologists (46% vs 22% for all other physicians), in the Midwest (31% vs 24% in all other regions), in whites (27% vs 21% in nonwhites), in privately insured @entity1 (31% vs 24% in all others), and in @entity1 (29% vs 23% in @entity1 ). Multiple logistic regression analysis showed independent effects of specialty, region, and sex. Other medications commonly used for @entity1 with @entity712 included diuretics (62% of visits for 1989-1994), digoxin (38%), and @entity460 channel antagonists (15%). Use of diuretics showed no significant trend between 1989 and 1994, whereas use of @entity6838 decreased significantly. CONCLUSION: The low rates of use of @entity1289 inhibitors in @entity1 with @entity712 and the wide variations in their use suggest a need to move beyond clinical trials and focus attention on modifying physician practices.

National patterns of XXXX inhibitor use in @entity712 .

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity712 :: ('MESH:D006333', 'Disease') :: ['congestive heart failure', 'CHF'] @entity1289 :: ('1636', 'Gene') :: ['ACE', 'angiotensin-converting enzyme'] @entity6838 :: ('MESH:D004077', 'Chemical') :: ['digoxin'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium']
@entity1289 :: (1636,Gene) :: ['angiotensin-converting enzyme']
