PURPOSE: The specificity of the @entity272 ( @entity272 ) is influenced by the previous BCG vaccination during childhood in Japan. The QuantiFERON (QFT) is expected to detect @entity281 among @entity378 contacts, however, its use is still limited. We report a case of @entity1906 outbreak that caused by a private lesson teacher. His sputum was found to be acidfast bacillus-positive (Gaffky 4) by smears examination. We evaluated the risk factors of @entity281 using @entity272 among contacts. MATERIAL AND METHOD: A total of 184 @entity1 were examined by a @entity272 . These results were used to estimate the rate of @entity281 by a mixture model. Logit analysis was also performed to estimate the number of infected @entity1 by using the relation between the positive rate of QFT and the size of erythema using a past report. We applied the Wells-Riley mathematical model of airborne transmission to calculate the risk of @entity281 . RESULT: As compared with @entity1 who had less contact with the index @entity1906 case, the estimated rate of @entity281 was higher among @entity1 who had close contact during the month before the index case started medical treatment (5% vs 23%). According to the model, the case added 1.1-4.0 quanta per hour (qph) to the room during a month before starting the treatment. CONCLUSION: These results suggest the importance of an early diagnosis of the index case to prevent @entity281 .

[The transmission of XXXX in a cram school].

@entity1 :: ('9606', 'Species') :: ['person', 'persons'] @entity281 :: ('MESH:D007239', 'Disease') :: ['TB infection', 'infection', 'latent infection'] @entity1906 :: ('MESH:D014390', 'Disease') :: ['TB'] @entity272 :: ('MESH:D012871', 'Disease') :: ['TST', 'tuberculin skin test'] @entity378 :: ('MESH:D014376', 'Disease') :: ['tuberculosis']
@entity378 :: (MESH:D014376,Disease) :: ['tuberculosis']
