The neonatal predictors of @entity4242 , defined as a head circumference <5th centile in @entity1 born preterm, has not been systematically assessed. @entity1 were drawn from the Developmental Epidemiology Network (DEN) cohort of very low-birthweight @entity1 (VLBW: 500-1500g) born from 1991 to 1993 at three sites in the USA. Neurological assessments were carried out among 198 singleton @entity1 (mean age 6 years 8 months, SD 0.5 years). Ninety-six @entity1 (48.5%) were male. @entity4242 was observed in 30 @entity1 (15%) and, using multivariate analysis, it was found to be associated with gestational age <26 weeks and @entity2107 ( @entity2107 ). Sonography-defined @entity62 ( @entity62 , i.e. echolucency or echodensities) was not associated with increased odds of @entity4242 , while occurrence of @entity548 ( @entity548 ) was in univariate but not multivariate analysis. In analyses that excluded @entity1 with @entity548 / @entity62 , odds of @entity4242 increased in dose-related fashion according to number of days on ventilator: >5 days, OR=4.5; 95%CI=1.4 to 15; >10 days, OR=5.7; 95%CI=1.7 to 19; >15 days OR=8.3; 95% CI=2.3 to 29.2. Among @entity1 without @entity2107 , @entity4242 was not associated with differences in IQ, while IQ scores among @entity1 with @entity2107 or any ventilation were disproportionately lower among those with @entity4242 . In multivariate analyses predicting IQ at age 7 years, @entity4242 was found to modify the association between neonatal @entity358 and IQ.

Factors associated with XXXX at school age in a very-low-birthweight population.

@entity1 :: ('9606', 'Species') :: ['children', 'Children'] @entity548 :: ('MESH:D006470', 'Disease') :: ['intraventricular hemorrhage', 'IVH'] @entity2107 :: ('MESH:D001997', 'Disease') :: ['bronchopulmonary dysplasia', 'BPD'] @entity358 :: ('MESH:D008171', 'Disease') :: ['lung disease'] @entity4242 :: ('MESH:D008831', 'Disease') :: ['Microcephaly', 'microcephaly'] @entity62 :: ('MESH:D056784', 'Disease') :: ['WMD', 'white-matter damage']
@entity4242 :: (MESH:D008831,Disease) :: ['microcephaly']
