BACKGROUND: The objective of this study was to evaluate the safety of total thyroidectomy for @entity1374 and summarise the treatment experience in a less-developed region. METHODS: This was a retrospective observational cohort study using the computerised database of the First Affiliated Hospital of Harbin Medical University. All consecutive thyroidectomy @entity1 from 2003 to 2014 were included in this study. Demographics, surgical procedure, diagnoses, morbidity and mortality were retrospectively reviewed. RESULTS: There were a total of 714 @entity1 and 4845 @entity1 in this study, with a mean age of 55 (range 9-87) years. A total of 4632 @entity1 underwent total thyroidectomy for primary surgical treatment, and 189 @entity1 previously underwent partial thyroidectomy. A total of 56.2% of the @entity1 had @entity1376 , including 12.23% who were @entity3935 . @entity2743 and @entity2621 were diagnosed in 2.82 and 7.23% of the @entity1 , respectively. @entity3557 was identified in 1336 @entity1 , 44.99% of whom had @entity7172 . The total prevalence of permanent complications of first-time and secondary surgeries was 0.35 and 7.41%, respectively. During thyroid surgery, 945 @entity1 underwent parathyroid autotransplantation. CONCLUSIONS: Initial total thyroidectomy can be safely performed for both benign and malignant @entity1374 in a less-developed region. The morbidity of a secondary surgical procedure after subtotal thyroidectomy is significantly high compared to first-time surgery.

Total thyroidectomy as primary surgical management for XXXX : surgical therapy experience from 5559 thyroidectomies in a less-developed region.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity3557 :: ('MESH:C536915', 'Disease') :: ['Papillary thyroid cancer'] @entity3935 :: ('MESH:D013958', 'Disease') :: ['thyrotoxic'] @entity2743 :: ('MESH:D006111', 'Disease') :: ["Graves' disease"] @entity2621 :: ('MESH:D050031', 'Disease') :: ["Hashimoto's disease"] @entity1376 :: ('MESH:C564546', 'Disease') :: ['multinodular goitre'] @entity7172 :: ('MESH:C563277', 'Disease') :: ['papillary microcarcinoma'] @entity1374 :: ('MESH:D013959', 'Disease') :: ['thyroid diseases', 'thyroid disorders']
@entity1374 :: (MESH:D013959,Disease) :: ['thyroid disease']
