OBJECTIVE: To distinguish the @entity4 , @entity130 , or @entity397 in the traumatic skeletal muscle fiber in vivo using diffusion tensor imaging (DTI) and tractography on magnetic resonance imaging (MRI). METHODS: The skeletal @entity121 models were made in 4 @entity95 (eight hindlimbs) by @entity68 discus (weight 1.0 kg, diameter 6 cm) falling down vertically from 45 cm height to @entity95 ' thighs. Conventional sequences and two-dimensional (2D) diffusion-weighted (DW) @entity9468 ( @entity9468 ) echo planar imaging (EPI) sequence with fat suppression (b = 600 s/mm2) were performed on 1. 5T MRI scanner. The grading of @entity4 , @entity130 , and fiber @entity397 in the damaged muscle were made according to their histopathological views, which was consistent with the images. The mean apparent diffusion coefficient (ADC) values and fractional anisotropy (FA) values were measured from the region of interests (ROIs) of all groups on 2D DW images used for tractography. Analysis of variance test was performed to analyze all data. RESULTS: ADC values of the areas in normal muscle, @entity4 muscle, @entity130 muscle, and ruptured muscle were (6.12 +/- 1.34) x 10(-3), (6.38 +/- 1.30) x 10(-3), (8.06 +/- 0.97) x 10(-3), and (9.57 +/- 0.93) x 10(-3) mm2/s, respectively. There was significant difference among groups (P < 0.001), but no difference between @entity4 muscle and normal muscle group (P > 0.05). The FA values of normal muscle, @entity4 muscle, @entity130 muscle, and ruptured muscle were 0.42 +/- 0.12, 0.36 +/- 0.12, 0.26 +/- 0.09, 0.12 +/- 0.08, respectively, with a significant difference among groups (P < 0.001). In the @entity4 muscle, the tracking cross-fiber could be seen but it decreased slightly. In the @entity130 muscle, the tracking fiber decreased markedly. In the ruptured muscle, the transverse-orientation tracking fiber vanished, yet some interrupted longitudinal-orientation tracking fiber could be found. CONCLUSION: The @entity4 , @entity130 , and @entity121 in @entity95 damaged skeletal muscle can be verified according to the ADC and the FA on DTI and tractography.

Grading of XXXX skeletal @entity121 by diffusion tensor imaging and tractography on magnetic resonance imaging.

@entity68 :: ('MESH:D007501', 'Chemical') :: ['iron'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity95 :: ('9986', 'Species') :: ['rabbits', 'rabbit'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture'] @entity9468 :: ('MESH:D014717', 'Disease') :: ['SE', 'spin-echo'] @entity121 :: ('MESH:D009135', 'Disease') :: ['muscle trauma', 'rupture of muscle fiber'] @entity130 :: ('MESH:D014947', 'Disease') :: ['injury']
@entity95 :: (9986,Species) :: ['rabbit']
