UNASSIGNED: OBJECT The authors sought to determine whether flow diversion with the Pipeline Embolization Device (PED) can approximate microsurgical decompression in restoring function after @entity129 following carotid @entity438 . METHODS This multiinstitutional retrospective study involved 45 @entity1 treated with PED across the United States. All @entity1 included presented between November 2009 and October 2013 with @entity129 (cranial nerves [CNs] II, III, IV, and VI) due to @entity438 . Outcome analysis included clinical and procedural variables at the time of treatment as well as at the latest clinical and radiographic follow-up. RESULTS Twenty-six @entity439 (57.8%) were located in the cavernous segment, while 6 (13.3%) were in the clinoid segment, and 13 (28.9%) were in the ophthalmic segment of the internal carotid artery. The average @entity439 size was 18.6 mm (range 4-35 mm), and the average number of flow diverters placed per @entity1 was 1.2. Thirty-eight @entity1 had available information regarding duration of @entity129 prior to treatment. Eleven @entity1 (28.9%) were treated within 1 month of symptom onset, while 27 (71.1%) were treated after 1 month of symptoms. The overall rate of @entity129 improvement for all @entity1 was 66.7%. The @entity51 resolved in 19 @entity1 (42.2%), improved in 11 (24.4%), were unchanged in 14 (31.1%), and worsened in 1 (2.2%). Overtime, the rate of @entity129 improvement was 33.3% (15/45), 68.8% (22/32), and 81.0% (17/21) at less than 6, 6, and 12 months, respectively. At last follow-up, 60% of @entity1 in the isolated @entity34857 group had improvement, while in the @entity16413 , IV, or VI group, 85.7% had improved. Moreover, 100% (11/11) of @entity1 experienced improvement if they were treated within 1 month of symptom onset, whereas 44.4% (12/27) experienced improvement if they treated after 1 month of symptom onset; 70.4% (19/27) of those with partial deficits improved compared with 30% (3/10) of those with complete deficits. CONCLUSIONS @entity129 caused by @entity438 responds similarly when the @entity439 is treated with the PED compared with open surgery and coil embolization. Lower morbidity and higher occlusion rates obtained with the PED may suggest it as treatment of choice for some of these lesions. Time to treatment is an important consideration regardless of treatment modality.

The fate of XXXX after flow diversion for carotid @entity439 .

@entity129 :: ('MESH:D003389', 'Disease') :: ['cranial neuropathy', 'Cranial neuropathy'] @entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity34857 :: ('22978', 'Gene') :: ['CN II'] @entity51 :: ('MESH:D009461', 'Disease') :: ['CN deficits'] @entity439 :: ('MESH:D000783', 'Disease') :: ['aneurysms', 'aneurysm'] @entity16413 :: ('51251', 'Gene') :: ['CN III'] @entity438 :: ('MESH:D002532', 'Disease') :: ['intracranial aneurysm', 'artery aneurysms', 'cerebral aneurysm']
@entity129 :: (MESH:D003389,Disease) :: ['cranial neuropathy']
