OBJECTIVE: Renal replacement therapy (RRT) is essential for maintenance of life for those with @entity454 . However, there remain many areas of uncertainty about which method of RRT should be chosen. This paper reports an economic model based on a systematic review that attempts to determine which method of dialysis, continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis, a @entity1 should have as the initial method of RRT. METHODS: A systematic review and a costing exercise carried out in a Scottish hospital were used to populate a Markov model. Scenario analysis was used to model plausible variations in variables included in the model. RESULTS: In 8 of the 16 scenarios developed hemodialysis dominated CAPD. In a further eight scenarios, the cost per life-year displayed considerable variability, ranging from between 5,000 Pounds to 51,000 Pounds. The higher costs per life-year were associated with minimum estimates of additional survival for a @entity1 starting RRT on hospital hemodialysis. CONCLUSION: It may be more cost-effective to manage @entity1 starting on RRT with hospital hemodialysis than CAPD. This has particular implications for the United Kingdom, given that up to 50% of new @entity1 receive CAPD.

Dialysis for XXXX . Determining a cost-effective approach.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal disease']
@entity454 :: (MESH:D007676,Disease) :: ['end-stage renal disease']
