BACKGROUND: Positive results from early clinical intervention of mild @entity131 (MTBI) @entity1 by rehabilitation specialists have been reported. Various treatments have been used, but few controlled studies are published. We hypothesised that early rehabilitation of selected MTBI @entity1 would reduce long term sequelae. METHOD: A randomised controlled trial with one year follow-up. Among 1719 consecutive @entity1 with MTBI, 395 individuals, 16-60 years of age, met the MTBI definition. Exclusion criteria were: previous clinically significant @entity75 and/or a history of @entity734 . The control group (n = 131) received regular care. The intervention group (n = 264) was examined by a rehabilitation specialist. 78 @entity1 were mainly referred to an occupational therapist. The problems were identified in daily activities and in terms of @entity6413 ( @entity6413 ), an individualised, tailored treatment was given. Primary endpoint was change in rate of @entity6413 and in life satisfaction at one-year follow-up between the groups. FINDINGS: No statistical differences were found between the intervention and control groups. @entity1 who experienced few @entity6413 two to eight weeks after the injury and declined rehabilitation recovered and returned to their pre-injury status. @entity1 who suffered several @entity6413 and accepted rehabilitation did not recover after one year. INTERPRETATION: In this particular MTBI sample, early active rehabilitation did not change the outcome to a statistically-significant degree. Further studies should focus on @entity1 with several complaints during the first 1-3 months and test various types of interventions.

Mild XXXX : the impact of early intervention on late sequelae. A randomized controlled trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity131 :: ('MESH:D001930', 'Disease') :: ['traumatic brain injury'] @entity75 :: ('MESH:D001927', 'Disease') :: ['brain disorders'] @entity6413 :: ('MESH:D038223', 'Disease') :: ['PCS', 'post-concussion symptoms'] @entity734 :: ('MESH:D019966', 'Disease') :: ['substance abuse']
@entity131 :: (MESH:D001930,Disease) :: ['traumatic brain injuries']
