BACKGROUND: The oesophageal leak pressure is defined as the pressure which breaks the seal between the cuff of a supraglottic airway and the peri-cuff mucosa, allowing penetration of fluid into the pharynx and the oral cavity. As a consequence, a decrease in this variable increases the risk of reflux and can lead to @entity358 . The aim of this study was to analyse the effects of cuff overinflation and pressure on the neck on the oesophageal leak pressure of seven supraglottic airways. METHODS: Three laryngeal masks, two laryngeal tubes, and two oesophageal-tracheal tubes were tested in an experimental setting. In five @entity1 cadavers, we simulated a sudden increase in oesophageal pressure. To measure baseline values (control), we used an intracuff pressure as recommended by the manufacturer. The first intervention included overinflation of the cuff by applying twice the amount of pressure recommended. A second intervention was defined as external pressure on the neck. RESULTS: The oesophageal leak pressure was decreased for laryngeal masks (control, 28 cm @entity4358 ; overinflation, 9 cm @entity4358 ; pressure on the neck, 8 cm @entity4358 ; P<0.01) and for laryngeal tubes (control, 68 cm @entity4358 ; overinflation, 37 cm @entity4358 ; pressure on the neck, 39 cm @entity4358 ; P<0.01) and was unaffected for oesophageal-tracheal tubes (control, 126 cm @entity4358 ; overinflation/pressure on the neck, 130 cm @entity4358 ; n.s.). CONCLUSION: Cuff overinflation and pressure on the neck can enhance the risk of @entity354 when using supraglottic airways. Therefore, both manoeuvres should be avoided in clinical practice.

Overinflation of the cuff and pressure on the neck reduce the preventive effect of supraglottic airways on @entity358 : an experimental study in XXXX cadavers.

@entity1 :: ('9606', 'Species') :: ['human'] @entity4358 :: ('D014867', 'Chemical') :: ['H2O'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary aspiration'] @entity354 :: ('MESH:D005764', 'Disease') :: ['gastro-oesophageal reflux']
@entity1 :: (9606,Species) :: ['human']
