OBJECTIVES: To evaluate the impact of laparoscopic excision of lesions on deep @entity46 related @entity249 . DESIGN: Retrospective study SETTING: Endometriosis tertiary referral centre POPULATION: A group of 115 @entity1 who had undergone laparoscopic surgery for @entity249 with histological confirmation of deep @entity46 . METHODS: @entity1 medical records and operative reports were reviewed. Telephone interviews were conducted for long-term follow up of fertility outcomes. MAIN OUTCOME AND MEASURES: Evaluation of fertility outcome following laparoscopic treatment of deep @entity46 by spontaneous conception and by assisted reproductive technology (ART) correlated with lesion number, size and localization (anterior, posterolateral, douglas and multiple localization). RESULTS: After a mean follow up of 22 months the overall pregnancy rate was 54.78 % (n=63) with a live-birth rate of 42.6% (n=49). Amongst those @entity1 given the chance to conceive spontaneously (n=70) the overall pregnancy rate was 60% (n=42), 38.5% (n=27) conceived spontaneously and 21.4% (n=15) by ART. The removal of multiple localization of the disease was associated with a higher pregnancy rate after surgery. When comparing isolated lesion size and disease localization there was no difference in pregnancy rate. Furthermore those @entity1 who underwent surgical eradication of the disease for the first time had a higher pregnancy rate (OR 4.18). CONCLUSIONS: This study demonstrates that laparoscopic excision of deep @entity46 enhances pregnancy rate, both by means of spontaneous conception or following use of assisted reproductive techniques. First surgical treatment of multiple lesions was associated with higher pregnancy rates while isolated lesions influenced the pregnancy-rate irrespective of their location and size.

The impact of laparoscopic surgical management of deep XXXX on pregnancy rate.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity249 :: ('MESH:D007246', 'Disease') :: ['infertility'] @entity46 :: ('MESH:D004715', 'Disease') :: ['endometriosis']
@entity46 :: (MESH:D004715,Disease) :: ['endometriosis']
