PURPOSE: Retinal nerve fiber layer (RNFL) will show @entity10747 following damage to the optic nerve or the optic tract in @entity1 with @entity977 . RNFL changes after surgery have not been studied thoroughly in @entity1 with the transsphenoidal surgery and @entity1 with the transcranial surgery. METHODS: Thirty-seven @entity1 with @entity977 were recruited from Huashan hospital between September 2010 and July 2014. @entity1 were divided into two groups: the transsphenoidal group and the transcranial group. Before surgery, 3 and 9  months after surgery, follow-up optic coherence tomography were conducted. RESULTS: Twenty-one @entity1 underwent transsphenoidal surgery and 16 @entity1 underwent transcranial surgery. No obvious difference were observed between these two groups before surgery. The mean RNFL thickness did not change significantly in @entity1 who underwent transsphenoidal surgery: 91.1 before surgery, 92.7 at 3  months after surgery (p  =  0.392) and 92.8 at 9  months after surgery (p  =  0.395). The mean RNFL thickness decreased in @entity1 who underwent transcranial surgery: 93.6 before surgery, 86.1 at 3  months after surgery (p  =  0.000) and 88.1 at 9  months after surgery (p  =  0.005). CONCLUSIONS: In the short time follow-up, there was no change of RNFL thickness in @entity977 @entity1 underwent transsphenoidal surgery, but a decrease in @entity1 underwent transcranial surgery.

Retinal nerve fiber layer changes after transsphenoidal and transcranial XXXX resection.

@entity1 :: ('9606', 'Species') :: ['patients', 'Patients'] @entity10747 :: ('MESH:D012183', 'Disease') :: ['retrograde degeneration'] @entity977 :: ('MESH:D010911', 'Disease') :: ['pituitary adenoma']
@entity977 :: (MESH:D010911,Disease) :: ['pituitary adenoma']
