UNASSIGNED: Coronary CT angiography (CCTA) is used in @entity1 with low-intermediate @entity662 presenting to the emergency department for its reliability in excluding @entity1187 ( @entity1187 ). However, its influence on medication modification in this setting is unclear. We sought to determine whether knowledge of CCTA-based @entity453 ( @entity453 ) was associated with change in statin and @entity117 prescription. We used the CCTA arm of the Rule Out Myocardial Infarction using Computed Angiographic Tomography II multicenter, randomized control trial (R-II) and comparison cohort from the observational Rule Out Myocardial Infarction using Computed Angiographic Tomography I cohort (R-I). In R-II, subjects were randomly assigned to CCTA to guide decision making, whereas in R-I @entity1 underwent CCTA with results blinded to caregivers and managed according to standard care. Our final cohort consisted of 277 subjects from R-I and 370 from R-II. @entity1187 rate was similar (6.9% vs 6.2% respectively, p  = 0.75). For subjects with CCTA-detected obstructive @entity453 without @entity1187 , initiation of statin was significantly greater after disclosure of CCTA results (0% in R-I vs 20% in R-II, p  = 0.009). Conversely, for subjects without CCTA-detected @entity453 , @entity117 prescription was lower with disclosure of CCTA results (16% in R-I vs 4.8% in R-II, p  = 0.001). However, only 68% of subjects in R-II with obstructive @entity453 were discharged on statin and 65% on @entity117 . In conclusion, physician knowledge of CCTA results leads to improved alignment of @entity117 and statin with the presence and severity of @entity453 although still many @entity1 with CCTA-detected @entity453 are not discharged on @entity117 or statin. Our findings suggest opportunity for practice improvement when CCTA is performed in the emergency department.

Use of Coronary Computed Tomographic Angiography Findings to Modify Statin and XXXX Prescription in @entity1 With Acute @entity662 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1187 :: ('MESH:D054058', 'Disease') :: ['ACS', 'acute coronary syndrome'] @entity662 :: ('MESH:D002637', 'Disease') :: ['chest pain'] @entity117 :: ('MESH:D001241', 'Chemical') :: ['aspirin'] @entity453 :: ('MESH:D003324', 'Disease') :: ['CAD', 'coronary artery disease']
@entity117 :: (MESH:D001241,Chemical) :: ['Aspirin']
