OBJECTIVE: To assess the frequency of external cerebrospinal fluid (CSF) drain-related CNS @entity281 before and after implementation of a protocol for their prevention. DESIGN: Quasi-experimental study, with comparison of incidence before and after the implementation of the intervention. SETTING AND @entity1 : Bambino Ges   @entity1 's Hospital in Rome, Italy. @entity1 receiving an external cerebrospinal fluid drain from 1 January 2013 to 31 March 2015. MAIN OUTCOME MEASURES: Drain-related @entity281 . RESULTS: Fifty-two @entity1 were included in the study. Before protocol implementation, cumulative incidence was 14 per 100 drains. Incidence rate was 8/1,000 catheter-days. After protocol implementation, cumulative incidence and incidence rate were 6.7 per 100 drains and 4.6 per 1,000 catheter-days (p=0.61 and p=0.2 versus the pre-intervention period, respectively). Infected @entity1 were significantly younger (median age: 16.5 days vs 13.4 months; p=0.026), had a significantly higher number of procedures (5 vs 1 procedure per @entity1 ; p <0.0001) and were most frequently affected by post-haemorrhagic @entity1276 of premature newborns (50% vs 16.7%; p=0.039), compared to non-infected @entity1 . CONCLUSIONS: After protocol implementation, we observed a reduction of incidence of CSF drain-related @entity281 , though the short post-intervention period limited the power of the study to detect a significant difference. @entity1 <1 year of age, with multiple interventions and post-haemorrhagic @entity1276 had higher risk of CSF drain-related @entity281 .

Reducing external drainage-related cerebrospinal fluid XXXX through implementation of a multidisciplinary protocol: experience in a paediatric hospital.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'Children', 'patient', 'PARTICIPANTS'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity1276 :: ('MESH:D006849', 'Disease') :: ['hydrocephalus']
@entity281 :: (MESH:D007239,Disease) :: ['infections']
