UNASSIGNED: It is known that specific alteration of rhythm in temperature (SART) stress produces @entity158 . However, it remains to be investigated whether SART stress induces @entity3825 . In this study, we investigated the @entity56 in the SART stress model by pharmacological tools and @entity10237 . Four-week-old @entity35 were exposed to repeated cold stress. @entity3825 was measured by visceromotor response to @entity14 , and the effects of @entity29940 and @entity4480 on @entity3825 were investigated in SART @entity35 . @entity10237 was given by @entity2951 injection into the left forepaw to induce @entity23 ( @entity23 ). SART stress induced @entity56 that was sustained at minimum for one week. In pharmacological analysis, alosetron and @entity4480 improved SART stress-induced @entity56 . @entity10237 induced @entity23 in normal conditions, but was disrupted in SART @entity35 . On the other hand, @entity18311 mRNA in distal colon was not affected by SART stress. In conclusion, SART @entity35 exhibit several features of @entity3825 in @entity5377 , and may be a useful model for investigating the central modification of @entity158 control in @entity5377 .

Specific alteration of rhythm in temperature-stressed XXXX possess features of abdominal pain in @entity5377 patients.

@entity29940 :: ('MESH:C090840', 'Chemical') :: ['alosetron'] @entity18311 :: ('29266(Tax:10116)', 'Gene') :: ['RMCP-II'] @entity5377 :: ('MESH:D053560', 'Disease') :: ['IBS'] @entity2951 :: ('MESH:D002211', 'Chemical') :: ['capsaicin'] @entity3825 :: ('MESH:D059265', 'Disease') :: ['Visceral pain', 'visceral pain'] @entity23 :: ('MESH:D007174', 'Disease') :: ['diffuse noxious inhibitory controls', 'DNIC'] @entity10237 :: ('MESH:D059226', 'Disease') :: ['heterotopical nociception', 'Heterotopical nociception'] @entity56 :: ('MESH:D004342', 'Disease') :: ['visceral hypersensitivity'] @entity4480 :: ('MESH:C058218', 'Chemical') :: ['duloxetine'] @entity158 :: ('MESH:D010146', 'Disease') :: ['somatic pain', 'pain'] @entity14 :: ('MESH:D015179', 'Disease') :: ['colorectal distension'] @entity35 :: ('10116', 'Species') :: ['Sprague-Dawley rats', 'rats']
@entity35 :: (10116,Species) :: ['rats']
