UNASSIGNED: Purpose To determine whether @entity1 with a solitary kidney are at higher risk for contrast material-induced @entity810 ( @entity810 ) than matched control @entity1 with bilateral kidneys. Materials and Methods This retrospective study was HIPAA compliant and approved by the institutional review board. Adult @entity1 with bilateral kidneys or a solitary kidney from unilateral nephrectomy who underwent contrast material-enhanced computed tomography (CT) at this institution from January 2004 to August 2013 were identified. The effects of contrast material exposure on the rate of @entity810 -defined as an increase in maximal observed serum @entity1011 (SCr) level of either (a) >= 0.5 mg/dL (44.2  mol/L) or (b) >= 0.3 mg/dL (26.52  mol/L) or 50% over baseline within 24-72 hours of exposure-and 30-day post-CT emergent dialysis and @entity204 were determined after propensity score-based 1:3 matching of @entity1 with solitary kidneys and control @entity1 with bilateral kidneys. Differences in clinical characteristics and outcomes between the solitary and bilateral kidney groups were assessed by using the Wilcoxon rank sum test or Pearson   (2) test prior to matching and by using conditional logistic regression after matching. Results Propensity score matching yielded a cohort of 247 @entity1 with solitary kidneys and 691 @entity1 with bilateral kidneys. The rate of @entity810 was similar between the solitary and bilateral kidney groups (SCr >=  0.5 mg/dL @entity810 definition odds ratio = 1.11 [95% confidence interval {CI}: 0.65, 1.86], P = .70; SCr >=  0.3 mg/dL or 50% over baseline @entity810 definition odds ratio = 0.96 [95% CI: 0.41, 2.07], P = .99). The rate of emergent dialysis was rare and also similar between cohorts (odds ratio = 1.87 [95% CI: 0.16, 16.4], P = .61). Although the rate of mortality was higher in the solitary kidney group (odds ratio = 1.70 [95% CI: 1.06, 2.71], P = .0202), chart review showed that no @entity204 was attributable to @entity810 . Conclusion Our study did not demonstrate any significant differences in the rate of @entity810 , dialysis, or @entity204 attributable to contrast-enhanced CT in @entity1 with a @entity8 . (  ) RSNA, 2015 Online supplemental material is available for this article.

Is the Presence of a Solitary Kidney an Independent Risk Factor for XXXX after Contrast-enhanced CT?

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['solitary kidney versus bilateral kidneys'] @entity810 :: ('MESH:D058186', 'Disease') :: ['AKI', 'acute kidney injury'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity810 :: (MESH:D058186,Disease) :: ['Acute Kidney Injury']
