BACKGROUND: Encouraging results on survival of @entity1 with @entity3620 have been shown with the use of cytoreductive surgery and perioperative intraperitoneal chemotherapy. This study explores the impact of aggressive surgical treatment on overall survival of @entity298 . METHODS: This is a retrospective analysis of prospectively collected clinical data of all @entity1 with diagnosis of @entity3620 treated in a designated referral centre in Greece. All @entity1 were offered cytoreductive surgery and intraperitoneal chemotherapy. @entity1 's characteristics, operative reports, pathology reports, and discharge summaries were stored in an electronic database and later reviewed and analysed. RESULTS: Cytoreduction for @entity298 was performed on 20 @entity1 (15 @entity1 and 5 @entity1 ) with a mean age of 59.4 years (SD 16.1). Mean @entity3906 index was 16.1 (SD 10.4) and the median completeness of cytoreduction score was 2 (range 1-2). Mean overall survival was 46.8 months (SE 4.03) with a mean of 21.4 and median of 18 months of follow-up. Disease-specific survival was 100% for the observed period. Univariate analysis showed the completeness of cytoreduction as the only possible predictor of survival. A median of 10 (range 4-14) peritonectomy procedures were performed per @entity1 . Median hospital stay was 14 (range 10-57 days). Grade III and IV complications occurred post-operatively in 5 @entity1 (25%). Two @entity1 died in the post-operative period of @entity1151 and @entity583 . CONCLUSION: Cytoreductive surgery with HIPEC has proved the most effective treatment even when taking account of the cost of significant morbidity.

Treating XXXX with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. A case series and review of the literature.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'Patient', 'men'] @entity3906 :: ('MESH:D010534', 'Disease') :: ['peritoneal cancer'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['pulmonary embolism'] @entity3620 :: ('MESH:C562839', 'Disease') :: ['malignant peritoneal mesothelioma'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity298 :: ('MESH:D010538', 'Disease') :: ['peritoneal mesothelioma']
@entity298 :: (MESH:D010538,Disease) :: ['peritoneal mesothelioma']
