CONTEXT: The impact of R1 resection on outcomes in @entity1 with @entity1124 ( @entity1124 ) is unclear, with most studies assessing survival for up to 5 years. OBJECTIVE: The aim of this study was to evaluate the prognostic influence of @entity4960 resection on >5-year survival in @entity1 with @entity1124 . MATERIAL AND METHODS: Of the 271 @entity1 with @entity1124 who underwent pancreatic resection over a 26-year period, 33 had survived for >= 5 years. R1 status was defined as the presence of @entity5 tissue  <=1 mm from a circumferential margin surface. @entity1 were followed-up for 61 to 288 months. RESULTS: Of the 33 long-term survivors, 19 and 14 underwent @entity4960 resection, respectively. The percentage of male @entity1 was significantly higher in the R1 than in the R0 group. The R0 group tended to show a weaker relationship between R status and stage than the R1 group. Multivariate analysis showed that R status was an independent prognostic marker (P=0.0071), and Kaplan-Meier curves showed that >5-year survivors in the R1 group had significantly poorer prognoses (P=0.002). CONCLUSIONS: @entity1 who have survived >5 years following R1 resection for @entity1124 can experience @entity5 recurrence in the resected area.

Influence of microscopically positive resection margins on long-term (>5-year) survival after resection of XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity4960 :: ('910', 'Gene') :: ['R0 and R1', 'R1 and R0'] @entity1124 :: ('MESH:D021441', 'Disease') :: ['PDAC', 'pancreatic ductal adenocarcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor']
@entity1124 :: (MESH:D021441,Disease) :: ['pancreatic ductal adenocarcinoma']
