The @entity1600 ( @entity1600 ) is the only focus of axillary metastasis in a significant proportion of @entity1 . In this single institutional study, clinicopathologic characteristics were investigated to determine the factors predicting the status of a @entity1600 biopsy and the metastatic involvement of non-SLNs. Data were retrospectively reveiwed for 400 consecutive @entity1 with clinical T1/T2 N0 @entity0 who underwent a @entity1600 biopsy including axillary and/or internal mammary lymph nodes. The SLNs were evaluated by using the new AJCC staging criteria following multiple sectioning and immunohistochemical (IHC) analyses of nodes. The @entity1600 contained @entity3 in 148 @entity1 (38.5%) including 18 @entity1 (12.2%) with micrometastases (<or=0.2 mm) and 130 @entity1 (87.8%) with macrometastases (>0.2 cm). Five @entity1 had @entity5 cells detected by IHC (<or=0.2 mm, N(0i)). @entity1 with @entity5 size more than 2 cm (T1, 29.8% versus T2, 51.6%; OR=2.31, 95% CI, 1.50-3.56) and lymphovascular invasion (LVI-, 30.3% versus LVI+, 51.3%; OR=2.07, 95% CI, 1.34-3.19) were more likely to have positive SLNs in both univariate and multivariate analyses. Among @entity1 with a positive @entity1600 biopsy, those with T2 @entity5 (versus T1; 63.1% versus 36.9; OR=2.93, 95% CI, 1.43-6.04), macrometastases in SLNs (versus micrometastases; 88.9% versus 11.1%; OR=8.83; 95% CI, 1.82-42.87) and extracapsular node extension (versus without extracapsular node extension; 65.4% versus 34.6%; OR, 2.23; 95% CI, 1.05-4.72) were more likely to have non- @entity1600 @entity3 in both univariate and multivarite analyses. These results indicate that clinicopathologic factors might be helpful to select @entity1 who were less likely to have negative @entity1600 or non-SLNs. However, additional factors are still needed to be identified to omit surgical axillary staging.

Factors predicting the sentinel and non- @entity1600 @entity3 in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'isolated tumor', 'tumors'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['sentinel lymph node', 'SLN'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
