OBJECTIVE: The purpose of this study was to retrospectively investigate whether preoperative MRI plays a key role in clinical prediction of micrometastasis (< 1 cm) to pelvic lymph nodes in @entity263 . MATERIALS AND METHODS: One hundred one @entity1 with @entity263 who underwent preoperative MRI and radical prostatectomy with pelvic lymph node dissection were included. None of the @entity1 had a pelvic lymph node with a short-axis diameter of 1 cm or larger on MRI. Both clinical ( @entity1486 , biopsy Gleason score, greatest percentage of biopsy core, and percentage of positive cores) and MRI parameters ( @entity5 apparent diffusion coefficient and @entity5 staging) were assessed. The univariate, multivariate, and ROC curve analyses were conducted. RESULTS: Of 101 @entity1 , nine (8.9%) had pelvic lymph node @entity3 . In univariate analysis, all of the clinical and MRI parameters were related to micrometastasis to pelvic lymph nodes (p < 0.05). However, multivariate analysis revealed that only preoperative MRI stage was significant (p = 0.044). AUC of preoperative MRI stage was 0.954 (odds ratio, 21.7). Respective sensitivity and specificity of preoperative @entity5 staging by MRI were 100% and 65.2% with cutoff of T3a or more, and 88.9% and 94.6% with cutoff of T3b for predicting micrometastasis to pelvic lymph nodes. CONCLUSION: Preoperative MRI staging may play a role in prediction of micrometastasis (< 1 cm) to pelvic lymph nodes in @entity263 .

Prediction of Micrometastasis (< 1 cm) to Pelvic Lymph Nodes in XXXX : Role of Preoperative MRI.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity263 :: ('MESH:D011471', 'Disease') :: ['prostate cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity3 :: ('MESH:D009362', 'Disease') :: ['metastases'] @entity1486 :: ('354', 'Gene') :: ['prostate-specific antigen']
@entity263 :: (MESH:D011471,Disease) :: ['Prostate Cancer']
