@entity2971 ( @entity2971 ) represent only 2-5% of adult germ cell @entity5 . Some publications from Asia have reported inferior treatment outcomes compared to data from an international study group. To ascertain whether this is generally the case, here we analyze treatment outcomes for 30 Japanese @entity1 with @entity2971 . The medical records of 30 @entity1 (25 nonseminomas and 4 pure @entity4797 ) treated from 1992 to 2002 were reviewed retrospectively. All @entity1 with @entity4797 achieved long survival except one who died of chemotherapy-related @entity295 . Ten and 11 @entity1 with @entity2971 presented with mediastinal and retroperitoneal primary sites, respectively. The 5-year @entity1349 ( @entity1349 ) and progression-free survival (PFS) for nonseminoma was 71% and 42%, respectively. The 5-year @entity1349 and PFS was 60% and 44%, respectively, for 10 @entity1 with mediastinal nonseminoma, and 91% and 48%, respectively, for @entity1 with @entity8678 . Tumor marker values on day 7 were available for 19 @entity1 . Among the 19 @entity1 in whom AFP or beta-HCG were measured on day 7, the values had declined in 12 @entity1 and were transiently elevated in 7 @entity1 compared to pretreatment values. The transient elevations of @entity5 markers were significantly associated with poor @entity1349 (P = 0.02) and PFS (P = 0.008). The treatment outcome of Japanese @entity1 with @entity2971 seemed to be comparable to that reported from international studies, suggesting no difference between ethnic groups. Transient @entity5 marker elevations on day 7 predict poor survival in @entity2971 @entity1 and may be a useful parameter for identifying @entity1 requiring more aggressive treatment.

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@entity1 :: ('9606', 'Species') :: ['patients'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity2971 :: ('MESH:D009373', 'Disease') :: ['Extragonadal germ cell tumors', 'EGCT'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'malignancies'] @entity8678 :: ('MESH:D012186', 'Disease') :: ['retroperitoneal nonseminoma'] @entity4797 :: ('MESH:D018239', 'Disease') :: ['seminomas', 'seminoma'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity2971 :: (MESH:D009373,Disease) :: ['Extragonadal germ cell tumors']
