We report 2 cases of signet ring cell @entity694 . Case 1: A 61-year-old @entity1 was admitted for lower @entity490 . Colonoscopy revealed an elevated lesion in the orifice of the appendix. @entity2580 was diagnosed on biopsy. The surgical findings showed multiple peritoneal dissemination nodules, while the @entity5 was unresectable owing to extensive invasion into the retroperitoneum. The histopathological findings were @entity2580 , T4b(retroperitoneum), NX, P3, Stage    . Although the @entity1 received 14 courses of treatment with S-1 as postoperative chemotherapy, he died of his illness at 32 postoperative months. Case 2: A 76-year-old @entity1 was admitted for @entity490 . Perforation of the lower gastrointestinal tract was diagnosed on abdominal CT, and an emergency operation was performed. The surgical findings demonstrated a large number of peritoneal dissemination nodules, cecal invasion of a sigmoid @entity5 , and perforation of the ascending colon. The @entity5 was thought to be unresectable, and the perforated segment was resected. The histopathological findings were @entity2580 , T4b(cecum), NX, P3, Stage    . Although 11 courses of treatment using FOLFIRI+ @entity1493 were administered as postoperative chemotherapy, the @entity1 died of his illness at 26 postoperative months.

[Experience of the Pharmacotherapy against Appendix and Sigmoid XXXX with the Peritoneal Dissemination].

@entity1 :: ('9606', 'Species') :: ['patient', 'man'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'primary tumor'] @entity2580 :: ('MESH:D018279', 'Disease') :: ['Signet ring cell carcinoma', 'signet ring cell carcinoma'] @entity1493 :: ('12064', 'Species') :: ['Bev'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity694 :: ('MESH:D003110', 'Disease') :: ['carcinoma of the appendix and colon']
@entity694 :: (MESH:D003110,Disease) :: ['Colon Signet Ring Cell Carcinoma']
