AIMS/HYPOTHESIS: Our aim was to examine the association of White's classification with obstetric and perinatal risk factors and outcomes in type 1 @entity6 @entity1 . METHODS: Obstetric records of a population-based cohort of 1,094 consecutive type 1 @entity6 @entity1 with a singleton childbirth during 1988-2011 were studied. The most recent childbirth of each @entity1 was included. RESULTS: The prepregnancy and the first trimester HbA1c increased from White's class B to F (p for trend <0.001). @entity551 and @entity1468 frequencies increased stepwise from class B to F (p for trends <0.001). Vaginal deliveries decreased and Caesarean sections and deliveries before 37  weeks increased from class B to F (p for trends <0.001). @entity8455 (p for trend   =   0.003) decreased and small-for-gestational age @entity1 (p for trend   =   0.002) and neonatal intensive care unit admissions (p for trend   =   0.001) increased from class B to F. In logistic regression analysis, White's classes were associated with @entity1468 but, with the exception of class R ( @entity989 ) and F ( @entity8 ), not with other adverse outcomes when adjusted for first trimester HbA1c >= 7% (>= 53  mmol/mol) and blood pressure >= 140/90  mmHg. First trimester HbA1c >= 7% was associated with @entity1468 , @entity3152 , fetal @entity8455 and neonatal intensive care unit admission. CONCLUSIONS/INTERPRETATION: White's classification is useful in estimating the risk of @entity1468 in early pregnancy independently of suboptimal glycaemic control and @entity101 . However, its utility in predicting adverse perinatal outcomes seems limited when information on first trimester HbA1c, blood pressure and @entity2412 is available.

White's classification and pregnancy outcome in XXXX with type 1 @entity6 : a population-based cohort study.

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'infants'] @entity8 :: ('MESH:D007674', 'Disease') :: ['nephropathy'] @entity3152 :: ('MESH:D007752', 'Disease') :: ['preterm delivery'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension'] @entity6 :: ('MESH:D003920', 'Disease') :: ['diabetic'] @entity989 :: ('MESH:D012164', 'Disease') :: ['proliferative retinopathy'] @entity1468 :: ('MESH:D011225', 'Disease') :: ['pre-eclampsia'] @entity2412 :: ('MESH:D048909', 'Disease') :: ['diabetic microvascular complications'] @entity8455 :: ('MESH:D005320', 'Disease') :: ['macrosomia', 'Fetal macrosomia'] @entity551 :: ('MESH:D007022', 'Disease') :: ['Systolic and diastolic blood pressure']
@entity1 :: (9606,Species) :: ['women']
