OBJECTIVES: The purpose of this study was to investigate the prognostic impact of @entity5 volume (TV) on @entity1 with stage I @entity1149 ( @entity1149 ) after complete resection. MATERIALS AND METHODS: We retrospectively reviewed the clinicopathological characteristics of 274 @entity1 with stage I @entity1149 who had received preoperative chest computed tomography (CT) scans and complete resection. TV was semi-automatically measured from chest CT scans by using an imaging software program. The optimal cutoff values of TV were determined by X-tile software. Disease-free survival (DFS) and @entity1349 ( @entity1349 ) were compared using Kaplan-Meier analysis. Univariate and multivariate analyses were performed to identify risk factors for DFS and @entity1349 . RESULTS: By using 3.046cm(3) and 8.078cm(3) as two optimal cutoff values of TV, the @entity1 were separated into three groups. The 5-year DFS and @entity1349 for @entity1 with TV<= 3.046cm(3), 3.046-8.078cm(3), and>8.078cm(3) were 88.0%, 73.6%, and 62.1%, respectively (P<0.001), and 91.4%, 84.5%, and 73.3%, respectively (p<0.001). Multivariate analysis showed that age and TV were independent factors associated with DFS. Sex, age, histology, visceral @entity3 , and TV were independent factors associated with @entity1349 . Stage Ia @entity1 might be separated into three groups on the basis of TV with significantly different DFS and @entity1349 . @entity1 with @entity5 diameter<= 2cm and 2-3cm were also stratified into two groups with significantly different DFS and @entity1349 on the basis of TV, respectively. CONCLUSION: TV is an independent risk factor for DFS and @entity1349 for stage I @entity1149 after complete resection. TV might provide additional prognostic information over @entity5 diameter in @entity1 with stage I @entity1149 .

The prognostic impact of XXXX volume on stage I @entity1149 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor'] @entity1149 :: ('MESH:D002289', 'Disease') :: ['NSCLC', 'non-small cell lung cancer'] @entity3 :: ('MESH:D009362', 'Disease') :: ['pleural invasion'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity5 :: (MESH:D009369,Disease) :: ['tumor']
