BACKGROUND: @entity1779 ( @entity1779 ) have been observed in the elderly and have been regarded as a manifestation of @entity6249 ( @entity6249 ). @entity8 may have a common source of pathogenesis because these organs are closely connected through anatomic and hemodynamic similarities. The purpose of this study was to clarify the associations between kidney biomarker levels and @entity1779 in @entity101 @entity1 . METHODS: The presence and number of @entity1779 were assessed on susceptibility-weighted imaging. We calculated the urinary albumin/ @entity1011 ratio (UACR) from morning spot urine and the estimated glomerular filtration rate (eGFR) in serum samples. Serum @entity9649 ( @entity9649 ) was measured with an automated particle-enhanced turbidimetric immunoassay. RESULTS: UACR and @entity9649 levels were higher in the @entity1 with @entity1779 than those without, and the eGFR was lower in the @entity1 with @entity1779 than those without. A logistic regression analysis indicates that eGFR and UACR were independently associated with the prevalence of deep or infratentorial @entity1779 . The odds ratio (OR) (95% confidence interval (CI)) of eGFR and UACR was 1.95 (1.37-3.27) and 2.25 (1.66-4.46), respectively. @entity9649 was independently associated with @entity1779 in both deep or infratentorial and lobar locations. The ORs (95% CI) were 2.59 (1.57-6.22) and 1.57 (1.15-4.85), respectively. Furthermore, @entity9649 exhibited fair diagnostic value for @entity1779 , with an area under the curve of 0.80. CONCLUSIONS: Kidney biomarker levels are associated with the presence of CMB in @entity101 @entity1 without a history of transient @entity63 attack (TIA) or @entity64 , independent of conventional risk factors, and @entity9649 was a better marker for @entity1779 than eGFR and UACR.

Associations Between Biomarkers of Renal Function With Cerebral Microbleeds in XXXX @entity1 .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity9649 :: ('1471', 'Gene') :: ['cystatin C', 'CysC'] @entity8 :: ('MESH:D007674', 'Disease') :: ['Cerebral and glomerular SVD'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertensive'] @entity6249 :: ('MESH:D059345', 'Disease') :: ['SVD', 'small vessel disease'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['Cerebral microbleeds', 'CMBs']
@entity101 :: (MESH:D006973,Disease) :: ['Hypertensive']
