INTRODUCTION: Internal carotid artery dissection with tandem internal carotid and @entity2500 may be responsible for large @entity385 that carries a general poor prognosis. Recanalization of internal carotid artery (ICA) dissection by stent-assisted thrombolysis has been recently proposed. We report two cases of acute symptomatic ICA dissection with @entity432 successfully treated with emergent endovascular stent-assisted thrombolysis using new self-expandable intracranial stents. METHODS: A 37-year-old @entity1 and a 59-year-old @entity1 were admitted in our hospital after acute severe symptoms of right-hemispheric @entity64 with National Institutes of Health @entity64 Scale (NIHSS) scores of 15 and 18, respectively. In both cases, magnetic resonance angiography showed @entity432 and angiography confirmed @entity432 with ICA dissection. An extensive mismatch region was diagnosed by Perfusion-diffusion MRI of the brain within 3 h after symptoms onset. Treatment was initiated 4 h after symptom onset by implantation of self-expandable intracranial stents into the dissected ICA and administration of intra-arterial recombinant tissue plasminogen activator. RESULTS: Recanalization of the ICA and @entity2500 ( @entity2500 ) was accomplished within 6 h after symptoms onset. In both cases, no periprocedural complication was observed and follow-up CT scan showed only a mild @entity4798 in the @entity2500 territory. After, respectively, 12 and 10 months follow-up, @entity1 had a favorable outcome with NIHSS 0 and mRS < or = 1. CONCLUSION: Endovascular stent-assisted thrombolysis appears to be a promising treatment in @entity432 due to ICA dissection. Our work underline the potential use of self-expandable intracranial stents in symptomatic acute ICA dissection.

Endovascular stent-assisted thrombolysis in XXXX .

@entity1 :: ('9606', 'Species') :: ['woman', 'patients', 'man'] @entity4798 :: ('MESH:D020520', 'Disease') :: ['brain infarct'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke', 'Stroke'] @entity2500 :: ('MESH:D020244', 'Disease') :: ['middle cerebral artery', 'middle cerebral artery occlusion', 'MCA'] @entity432 :: ('MESH:D001157', 'Disease') :: ['tandem occlusion'] @entity385 :: ('MESH:D002544', 'Disease') :: ['cerebral infarction']
@entity432 :: (MESH:D001157,Disease) :: ['acute occlusive carotid artery dissection']
