BACKGROUND: BMI is one factor that is used to determine a @entity1 's eligibility for lipid screening and treatment. BMI, which is an indirect measure of body fat, may inadequately represent the biological effect of body fat percentage on lipid concentrations. OBJECTIVE: We examined the relation between directly measured body fat percentage and lipid concentrations in a representative sample of US youths. DESIGN: Data from 7821 @entity1 aged 8-19 y from the 1999-2004 NHANES were analyzed. Body fat percentage was measured by dual-energy X-ray absorptiometry. Total and HDL- @entity165 concentrations were measured in serum. Serum @entity412 and LDL- @entity165 concentrations were measured in a subsample of 2661 fasting NHANES @entity1 aged 12-19 y. Prevalences of adverse total @entity165 (>200 mg/dL), LDL @entity165 (>130 mg/dL), @entity1674 (>150 mg/dL), and HDL @entity165 (<35 mg/dL) were measured. RESULTS: Approximately 10.0% [  0.7% (SE)] of @entity1 had high total @entity165 , 7.0    0.4% of @entity1 had low HDL @entity165 , 9.7    1.0% of @entity1 had high @entity1674 , and 7.6    0.7% of @entity1 had high LDL @entity165 . Prevalence of adverse total @entity165 , HDL @entity165 , @entity1674 , and LDL @entity165 in US youths with high adiposity (greater than or equal to the age- and sex-specific 75th percentile of body fat percentage) was significantly greater (P < 0.01) than for @entity1 without high adiposity. In multiple linear regressions adjusted for age, survey period, and race-ethnicity, the variance in lipid concentrations explained by body fat percentage was 2-20% (P < 0.001). CONCLUSION: Adverse lipid concentrations and high adiposity are significantly associated in youths.

Association of body fat percentage with lipid concentrations in XXXX and adolescents: United States, 1999-2004.

@entity1 :: ('9606', 'Species') :: ['participants', 'child'] @entity1674 :: ('MESH:D014280', 'Chemical') :: ['triglycerides'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol']
@entity1 :: (9606,Species) :: ['children']
