Since June 1993, unilateral laparoscopic retroperitoneal lymph node dissection (LRPLND) was performed in 6 @entity1 diagnosed with clinical stage I nonseminomatous @entity2971 (NSGCT). All of the @entity1 had undergone prior radical orchiectomy. The @entity5 was left-sided in three cases and right-sided in three cases. Preoperative staging by means of @entity5 markers assessment, computerized tomography scan (CT) of the chest and abdomen and chest X-ray was unremarkable for metastatic disease. All procedures were accomplished without any complications in a mean time of 325 min (275 to 420 min). The estimated peri- and postoperative @entity190 was minimal. Of note, the comparison between the hematocrit and hemoglobin decrease of LRPLND and RPLND showed a statistically significant reduction (3.1 vs 11.1% P < 0.01 and 1.1 vs 3.2 g/dl P < 0.01). None of the @entity1 required blood transfusion. In the case of the first @entity1 the hospital stay was 18 days due to a widespread @entity9285 . In the remaining five cases the average hospitalization was 4.8 days ranging between 4 and 6 days. The @entity1 resumed normal activities within 12 to 27 days (mean 16.2 days) postoperatively. Mean number of lymph nodes removed was 6.8, ranging between 5 and 9. Histologic examination of the dissected lymph nodes revealed microscopic metastases from @entity189 in two @entity1 . Both of these @entity1 were subject to adjuvant chemotherapy. The mean follow-up period @entity16222 .3 months, ranging between 18 and 48 months. To date, no relapses have been observed. In accordance with other reports, we believe that LRPLND is both feasible and effective. However, larger and more comprehensive studies with long-term follow-up are required to determine whether this approach is reliable and definitely superior to standard open surgery in the management of clinical stage I NSGCT.

[Laparoscopic unilateral retroperitoneal lymphadenectomy in XXXX of the testis in clinical stage I].

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity9285 :: ('MESH:D013352', 'Disease') :: ['subcutaneous emphysema'] @entity2971 :: ('MESH:D009373', 'Disease') :: ['germ cell tumors'] @entity190 :: ('MESH:D006473', 'Disease') :: ['blood loss'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'testicular cancer'] @entity16222 :: ('MESH:C038900', 'Chemical') :: ['is 33'] @entity189 :: ('MESH:D002277', 'Disease') :: ['embryonal carcinoma']
@entity5 :: (MESH:D009369,Disease) :: ['non-seminomatous neoplasms']
