UNASSIGNED: Pre-treatment with antiplatelet agents is described to be a risk factor for mortality after spontaneous @entity1779 ( @entity1779 ). However, the impact of antithrombotic agents on mortality in @entity1 who undergo @entity1410 evacuation compared to conservatively treated @entity1 with @entity1779 remains controversial. This analysis is based on a prospective registry for quality assurance in @entity64 care in the State of Hesse, Germany. @entity1 ' data were collected between January 2008 and December 2012. Only @entity1 with the diagnosis of spontaneous @entity1779 were included (International Classification of Diseases 10th Revision codes I61.0-I61.9). Predictors of in-hospital mortality were determined by univariate analysis. Predictors with P<0.1 were included in a binary logistic regression model. The binary logistic regression model was adjusted for age, initial Glasgow @entity772 Score (GCS), the presence of @entity548 ( @entity548 ), and pre- @entity1779 disability prior to ictus. In 8,421 @entity1 with spontaneous @entity1779 , pre-treatment with oral anticoagulants or antiplatelet agents was documented in 16.3% and 25.1%, respectively. Overall in-hospital mortality was 23.2%. In-hospital mortality was decreased in operatively treated @entity1 compared to conservatively treated @entity1 (11.6% versus 24.0%; P<0.001). Patients with antiplatelet pre-treatment had a significantly higher risk of @entity204 during the hospital stay after @entity1410 evacuation (odds ratio [OR]: 2.5; 95% confidence interval [CI]: 1.24-4.97; P=0.010) compared to patients without antiplatelet pre-treatment treatment (OR: 0.9; 95% CI: 0.79-1.09; P=0.376). In conclusion a higher rate of in-hospital mortality after pre-treatment with antiplatelet agents in combination with @entity1410 evacuation after spontaneous @entity1779 was observed in the presented cohort.

In-hospital mortality after pre-treatment with antiplatelet agents or oral anticoagulants and XXXX evacuation of intracerebral @entity1410 .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity548 :: ('MESH:D006470', 'Disease') :: ['intraventricular hemorrhage', 'IVH'] @entity772 :: ('MESH:D003128', 'Disease') :: ['Coma'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity1779 :: ('MESH:D002543', 'Disease') :: ['ICH', 'intracerebral hemorrhage']
@entity1410 :: (MESH:D006406,Disease) :: ['hematoma']
