"Blue eye" disease of @entity1707 in Mexico is caused by @entity70216 and characterized by @entity249 in sows and boars, nervous signs in young @entity1707 , and @entity5575 in @entity1707 of all ages. The pathogenesis of reproductive tract lesions in rubulavirus-infected boars has not previously been investigated. In a first experiment, four 9-month-old boars were inoculated with @entity70216 and killed 5, 15, 30 or 45 days post-inoculation (pi). In a second experiment, four similar boars were inoculated with the same virus and two animals were killed on each of days 70 and 80 pi. Swelling of the head of the epididymis developed in all inoculated boars at approximately day 15 pi. @entity1319 and concentration were detected in semen samples collected from one boar from day 21 pi. At post-mortem examination, nodules were seen in the head of the epididymis of the boars killed 15, 30 or 45 days pi and the right testis of the @entity1707 killed 30 days pi was @entity3202 . Corresponding histopathological epididymal alterations included formation of spermatic @entity738 and @entity13312 of ductular epithelium. These lesions were associated with mononuclear cell infiltration and interstitial @entity3385 . Degeneration of seminiferous tubules and interstitial mononuclear cell infiltration were seen in the @entity3202 of the @entity1707 killed 30 days pi. There was @entity82 of the head of the epididymis in all boars killed 70 or 80 days pi and one of these animals also had right testicular @entity194 associated with degeneration of seminiferous tubules, lymphocytic infiltration and giant cell formation. Porcine rubulavirus antigen was detected by immunofluorescence labelling in the head of the epididymis of the @entity1707 killed 15, 30 or 45 days pi and in one animal killed on day 70 pi. These results indicate that @entity70216 can cause severe @entity11570 and reduced semen quality in sexually mature boars.

Lesions in the reproductive tract of boars experimentally infected with XXXX .

@entity1707 :: ('9823', 'Species') :: ['pigs', 'pig'] @entity249 :: ('MESH:D007246', 'Disease') :: ['infertility'] @entity82 :: ('MESH:D005355', 'Disease') :: ['fibrosis'] @entity738 :: ('MESH:D006099', 'Disease') :: ['granulomas'] @entity13312 :: ('MESH:C536522', 'Disease') :: ['vacuolar degeneration'] @entity5575 :: ('MESH:D003318', 'Disease') :: ['corneal opacity'] @entity3202 :: ('MESH:D016109', 'Disease') :: ['atrophic', 'atrophic testis'] @entity70216 :: ('53179', 'Species') :: ['porcine rubulavirus'] @entity11570 :: ('MESH:D009920', 'Disease') :: ['epididymo-orchitis'] @entity194 :: ('MESH:D001284', 'Disease') :: ['atrophy'] @entity3385 :: ('MESH:D012178', 'Disease') :: ['fibroplasia'] @entity1319 :: ('MESH:D015835', 'Disease') :: ['Reduced spermatozoan motility']
@entity70216 :: (53179,Species) :: ['porcine rubulavirus']
