The aim of the work was to study sex-specific differences between certain risk factors of @entity65 and hemodynamic parameters in elderly subjects and their relation to age-specific diseases and genealogic history of longevity. Total @entity165 , @entity412 , @entity413 , fibrinogen, @entity414 , @entity1133 , @entity1011 levels in plasma and arterial pressure (AP) were measured. Hemodynamic parameters were calculated by the formulas for the @entity64 volume, cardiac output, myocardial contractility, pulse pressure, total peripheral resistance (TPR), endurance factor of cardiac activity, and Kerdo index. Each new decade of life was characterized by peculiar hemodynamic patterns. Pulse AP (PAP) and TPR increased with age and was associated with sex-related metabolic changes. Elderly @entity1 presented with hypocholesterolemia and @entity417 . Total @entity165 , fibrinogen, and @entity413 levels did not correlate with age. To conclude, elevated PAP, TPR, and @entity4346 are risk factors of @entity65 in old subjects. Combination of several risk factors in young and middle-age subjects reduces prognostic value of the longevity factor in the familial history. Aging is accompanied by the development of gender-related differences in metabolic parameters.

[Aging, age-related diseases, and certain risk factors of XXXX in subjects of advanced and senile age].

@entity1 :: ('9606', 'Species') :: ['men'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anemia'] @entity1133 :: ('MESH:D014508', 'Chemical') :: ['urea'] @entity412 :: ('CHEBI:17855', 'Chemical') :: ['triglyceride'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['left ventricular hypertrophy'] @entity65 :: ('MESH:D002318', 'Disease') :: ['cardiovascular diseases'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity413 :: ('MESH:D005947', 'Chemical') :: ['glucose'] @entity165 :: ('MESH:D002784', 'Chemical') :: ['cholesterol'] @entity414 :: ('MESH:D014527', 'Chemical') :: ['uric acid']
@entity65 :: (MESH:D002318,Disease) :: ['cardiovascular diseases']
