STUDY DESIGN: It is well known that changes of the body temperature as well as @entity130 influence the blood flow in the brain and spinal cord. However, there is still a lack of knowledge concerning the levels of blood flow changes, especially during @entity2332 . OBJECTIVES: This investigation was carried out to examine the effects of systemic @entity2332 and @entity130 on @entity602 ( @entity602 ). METHODS: Twenty-four @entity35 were randomized either to thoracic laminectomy only (Th VII-IX) or to 35 g spinal cord compression @entity130 . The animals were further randomized to either constant normothermia (38 degrees C) or to a systemic cooling procedure, ie reduction of the esophageal temperature from 38 to 30 degrees C. @entity602 was recorded 5 mm caudal to the injury zone using Laser-Doppler flowmetry which allows a non-invasive continuous recording of local changes in the blood flow. The autoregulation ability was tested at the end of the experiments by inducing a 30-50 mmHg blood-pressure fall, using blood-withdrawal from the carotid artery. RESULTS: The mean @entity602 decreased 2.8% and 3.5% per centigrade reduction of esophageal temperature in the animals sustained to @entity2332 with and without @entity130 , respectively. This could be compared to a decrease of 0.2%/min when only @entity130 was applied. No significant differences were seen between the groups concerning auto regulatory ability. CONCLUSIONS: Our results indicate that the core temperature has a high impact on the @entity602 independent of previous @entity130 recorded by Laser-Doppler flowmetry. This influence exceeds the response mediated by moderate compression @entity130 alone.

Spinal cord blood flow changes following systemic XXXX and spinal cord compression injury: an experimental study in the @entity35 using Laser-Doppler flowmetry.

@entity35 :: ('10116', 'Species') :: ['rats'] @entity602 :: ('MESH:D013118', 'Disease') :: ['SCBF', 'spinal cord blood flow'] @entity2332 :: ('MESH:D007035', 'Disease') :: ['hypothermia'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity2332 :: (MESH:D007035,Disease) :: ['hypothermia']
