PURPOSE: To examine the accuracy of the cardiothoracic ratio (CTR) at routine computed tomography (CT) of the chest to diagnose @entity1283 by using echocardiography (ECHO) as a criterion standard, and secondarily, to search for @entity299 correlating with @entity4346 ( @entity4346 ) at ECHO. MATERIALS AND METHODS: We searched 2 databases: @entity5 @entity1 who had chest CT who also underwent routine ECHO by one experienced cardiologist, from January to March 2008. Consecutive @entity1 were enrolled who had chest radiography (CXR) within 1 month and ECHO within 6 months of CT. Cardiothoracic ratio was defined as the transverse greatest cardiac diameter from outer to outer myocardium on axial images divided by the transverse greatest thoracic diameter from inner to inner chest wall on axial images, as measured by 2 board-certified radiologists. Left ventricular short diameter on CT was measured from inner to inner myocardium. @entity4346 at ECHO was defined using the standard American Society of Echocardiography criteria. Other data captured included cardiac and chemotherapy history, and secondary signs of @entity712 . The Pearson correlation coefficient (r) and Wilcoxon rank sum tests and receiver operating characteristic (ROC) curves were used for statistical analysis. RESULTS: 101 @entity1 , 52 @entity1 and 49 @entity1 , with a mean age of 58 years met the entry criteria. Cardiothoracic ratio at CXR and CT were highly correlated (r = 0.802) (P < 0.001). There was moderate ability of CT CTR to identify @entity4346 (area under the receiver operating characteristic curve AUC = 0.70; 95% CI, 0.51-0.90). The CT left ventricular short diameter showed moderate correlation with the ECHO left ventricular internal diameter (r = 0.49) and left ventricular mass (r = 0.37). CONCLUSION: In @entity1 with @entity5 undergoing routine ECHO, the cardiothoracic ratio at routine CT scans was highly correlated with that at CXR. Preliminary estimates in this small study indicate a low likelihood of @entity4346 when the CTR is less than 0.49.

Shall we report XXXX at routine computed tomography of the chest?

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'men'] @entity712 :: ('MESH:D006333', 'Disease') :: ['heart failure'] @entity5 :: ('MESH:D009369', 'Disease') :: ['cancer'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['cardiomegaly'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['Left ventricular hypertrophy', 'left ventricular hypertrophy', 'LVH'] @entity299 :: ('MESH:D006331', 'Disease') :: ['CT cardiac measurements']
@entity1283 :: (MESH:D006332,Disease) :: ['cardiomegaly']
