OBJECTIVE: @entity1028 ( @entity1028 ) repair is a complex procedure performed in @entity1 at high cardiovascular risk. High volume intra-operative @entity548 is often recorded, and the amount of intra-operative blood product transfusion is associated with relevant morbidity and mortality. The aim of the study was to identify pre-operative predictors of intra-operative @entity1503 ( @entity1503 ) to stratify @entity1 pre-operatively. METHODS: This was a retrospective analysis of prospectively collected data of all @entity1 who underwent open @entity1028 surgery at San Raffaele Scientific Institute from January 2009 to December 2015. Intra-operative red blood cell (RBC) transfusions were administered to maintain a hematocrit of at least 30%. A @entity1503 was defined as a transfusion of at least four RBC units, corresponding to 1000  mL. RESULTS: The study population included 428 @entity1 : 260 (61%) received fewer than 4 RBC units, and 168 (39%) were transfused with at least 4 RBC units. In @entity1 who underwent @entity1503 , higher mortality was observed after surgery (p=.003), longer intensive care unit admission (p=.004), and longer mechanical ventilation compared with less transfused @entity1 (p=.0002). The @entity1 who received fewer units were administered a higher dose of heparin during the surgical operation compared with @entity1 of the @entity1503 group: 3400  1100 vs. 2900  1300 IU (international units) (p=.0004). Pre-operative @entity177 (OR 1.8), the pre-operative haemoglobin value (OR 0.8), and the need for urgent or emergent surgery (OR 3.15) were independent predictors of @entity1503 on multivariate analysis. CONCLUSIONS: The identification of @entity1 at risk of intra-operative @entity1503 during @entity1028 surgery is critical as these @entity1 experience a worse outcome. Nevertheless, only few independent predictors are available for clinical practice.

Predicting the Need for Intra-operative Large Volume Blood Transfusions During XXXX Repair.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity177 :: ('MESH:D051437', 'Disease') :: ['chronic renal failure'] @entity1503 :: ('MESH:D006402', 'Disease') :: ['LVBT', 'large volume blood transfusions'] @entity1028 :: ('MESH:D017544', 'Disease') :: ['TAAA', 'Thoraco-abdominal aortic aneurysm']
@entity1028 :: (MESH:D017544,Disease) :: ['Thoraco-abdominal Aortic Aneurysm']
