BACKGROUND:    @entity3001 @entity1 with @entity8831 are said to have post-treatment @entity3001 symptoms (PTLDS) if there is persistence of subjective symptoms for at least 6 months following antibiotic treatment and resolution of the @entity272 . The purpose of this study was to characterize PTLDS in @entity1 with culture-confirmed early @entity3001 followed for >10 years. METHODS:    Adult @entity1 with @entity8831 with a positive skin or blood culture for @entity2069 were enrolled in a prospective study beginning in 1991 and followed up at 6 months and annually thereafter to determine the long-term outcome of this infection. The genotype of the infecting strain of @entity2069 was evaluated in subjects with PTLDS. RESULTS:    One hundred twenty-eight subjects with culture-confirmed early @entity3001 , of whom 55% were male, were followed for a mean    SD of 14.98    2.71 years (median = 15 years; range = 11-20 years). Fourteen (10.9%) were regarded as having possible PTLDS, but only 6 (4.7%) had PTLDS documented at their last study visit. Nine (64.3%) had only a single symptom. None of the 6 with PTLDS at their last visit was considered to be functionally impaired by the symptom(s). PTLDS was not associated with a particular genotype of @entity2069 . CONCLUSIONS:    PTLDS may persist for >10 years in some @entity1 with culture-confirmed early @entity3001 . Such long-standing symptoms were not associated with functional impairment or a particular strain of @entity2069 .

Long-term Assessment of Post-Treatment Symptoms in XXXX With Culture-Confirmed Early Lyme Disease.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3001 :: ('MESH:D008193', 'Disease') :: ['Lyme disease'] @entity2069 :: ('139', 'Species') :: ['B. burgdorferi', 'Borrelia burgdorferi'] @entity8831 :: ('MESH:C538499', 'Disease') :: ['erythema migrans'] @entity272 :: ('MESH:D012871', 'Disease') :: ['skin lesion']
@entity1 :: (9606,Species) :: ['Patients']
