BACKGROUND: Few studies have investigated the relationship of anthropometric measurements with computed tomography (CT) body fat composition, and even fewer determined if these relationships differ by sex and race. METHODS: CT scans from 1,851 @entity1 in the population based Multi-Ethnic Study of @entity731 were assessed for visceral and subcutaneous fat areas by semi-automated segmentation of body compartments. Regression models were used to investigate relationships for anthropometry with visceral and subcutaneous fat separately by sex and race/ethnicity. RESULTS: @entity1 were 50% female, 41% Caucasian, 13% Asian, 21% African American, and 25% Hispanic. For visceral fat, the positive relationship with weight (p = 0.028), waist circumference (p<0.001), waist to hip ratio (p<0.001), and waist to height ratio (p = 0.05) differed by sex, with a steeper slope for @entity1 . That is, across the range of these anthropometric measures the rise in visceral fat is faster for @entity1 than for @entity1 . Additionally, there were differences by race/ethnicity in the relationship with height (p<0.001), weight (p<0.001), waist circumference (p<0.001), hip circumference (p = 0.006), and waist to hip ratio (p = 0.001) with the Hispanic group having shallower slopes. For subcutaneous fat, interaction by sex was found for all anthropometric indices at p<0.05, but not for race/ethnicity. CONCLUSION: The relationship between anthropometry and underlying adiposity differs by sex and race/ethnicity. When anthropometry is used as a proxy for visceral fat in research, sex-specific models should be used.

The Sex and Race Specific Relationship between Anthropometry and Body Fat Composition Determined from Computed Tomography: Evidence from the Multi-Ethnic Study of XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'women', 'Participants', 'men'] @entity731 :: ('MESH:D050197', 'Disease') :: ['Atherosclerosis']
@entity731 :: (MESH:D050197,Disease) :: ['Atherosclerosis']
