In a unit serving a population of three million, 60 @entity101 @entity1 with @entity455 were identified over a 10-year period. The presence of @entity455 was usually suggested by intravenous urography (IVU), although this was falsely negative in 21 per cent of cases; isotope renography (IR) was normal in a similar proportion of @entity1 (25 per cent). Eight @entity1 were treated medically and 52 underwent surgical procedures; nephrectomy in 32, autotransplantation in 10, by pass graft in six and percutaneous transluminal angioplasty in four. Twenty-three per cent of @entity1 were cured, 37 per cent improved and 40 per cent unchanged one year after surgery, but the response could not be accurately predicted. Clinical features were of some value in that those @entity1 most likely to benefit from surgery were younger, had less severe @entity101 of shorter duration, smoked less, had less severe @entity989 and less @entity1283 . There was also a trend for those with better renal function and less electrocardiographic evidence of left @entity123 to benefit from surgery. The IVU and IR did not predict response to surgery but arteriographic appearances of @entity4267 indicated there should be a favourable response. The renal vein @entity916 ratio, basal or stimulated, was of no prognostic value since approximately two-thirds of @entity1 with ratios above or below the threshold value had some benefit from surgery. We conclude that the surgical treatment of @entity2792 is worthwhile but the number of @entity1 suitable for surgery is small. Clinical features and the results of simple investigations provided the best guide to surgical outcome in our @entity1 .

XXXX : ten years' experience in a regional centre.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity455 :: ('MESH:D014652', 'Disease') :: ['renovascular disease'] @entity101 :: ('MESH:D006973', 'Disease') :: ['hypertension', 'hypertensive'] @entity1283 :: ('MESH:D006332', 'Disease') :: ['cardiomegaly'] @entity916 :: ('5972', 'Gene') :: ['renin'] @entity2792 :: ('MESH:D006978', 'Disease') :: ['renovascular hypertension'] @entity4267 :: ('MESH:D005352', 'Disease') :: ['fibromuscular dysplasia'] @entity989 :: ('MESH:D012164', 'Disease') :: ['retinopathy'] @entity123 :: ('MESH:D024741', 'Disease') :: ['ventricular hypertrophy']
@entity2792 :: (MESH:D006978,Disease) :: ['Renovascular hypertension']
