OBJECTIVE: To assess the impact of @entity955 ( @entity955 ) and sinus rhythm restoration on the distribution of reticulated platelets (RPs), which are known to be associated with @entity715 propensity and have a greater predilection for @entity715 participation. @entity1 AND METHODS: The RP content was assessed by flow cytometry (thiazole orange/ @entity1428 ) in 110 consecutive @entity1 with @entity955 before and 3 to 4 months after catheter ablation of the pulmonary veins. Results were compared with those of 55 age- and sex-matched controls with normal sinus rhythm. RESULTS: The mean    SD percentage of RPs was higher in @entity1 with @entity955 compared with controls (28.5%  7.3% vs 6.4%  5.3%; P<.001). The RP content did not vary by CHA2DS2-VASc score. After catheter ablation of the pulmonary veins, 63 @entity1 were available for follow-up assessment. A significant reduction of RPs was observed compared with preintervention values (29.85%  7.1% vs 20.79%  7.6%; P<.001). During follow-up, 19% of @entity1 (12 of 63) had confirmed AF recurrence. The mean    SD percentage of RPs was higher in this group than in those without a recurrence (24.7%  6.5% vs 18.9%  7.5%; P=.01). CONCLUSION: Nonvalvular @entity955 affects the percentage of RPs, independent of the CHA2DS2-VASc score. After ablation, RP content dropped significantly. High RP content in @entity1 with @entity955 may explain the potential mechanism of @entity1031 complications and the lack of efficacy of currently available antiplatelet therapy for @entity64 prevention in this @entity943 .

Impact of XXXX and Sinus Rhythm Restoration on Reticulated Platelets.

@entity1 :: ('9606', 'Species') :: ['patients', 'PARTICIPANTS'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1031 :: ('MESH:D013923', 'Disease') :: ['thromboembolic'] @entity1428 :: ('3690', 'Gene') :: ['CD61'] @entity955 :: ('MESH:D001281', 'Disease') :: ['atrial fibrillation', 'nonvalvular atrial fibrillation', 'NVAF'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombus', 'thrombotic'] @entity943 :: ('MESH:D001145', 'Disease') :: ['dysrhythmia']
@entity955 :: (MESH:D001281,Disease) :: ['Atrial Fibrillation']
