INTRODUCTION: Survivors of @entity3166 ( @entity3166 ) often develop a post- @entity3166 intestinal stricture, causing severe and prolonged morbidity. OBJECTIVES: We first aimed to determine the incidence of post- @entity3166 strictures. Second, we aimed to determine risk factors associated with intestinal post- @entity3166 strictures. MATERIALS AND METHODS: A total of 441 @entity1 diagnosed with @entity3166 Bell's stage >= 2 were retrospectively included in three academic pediatric surgical centers between January 2005 and January 2013. Clinical data were related to the occurrence of intestinal post- @entity3166 strictures. Post- @entity3166 strictures were defined as clinically relevant strictures with a radiological and/or surgical confirmation of this post- @entity3166 stricture. RESULTS: The median gestational age of the 337 survivors of the acute phase of @entity3166 was 29weeks (range 24-41) and median birth weight was 1130g (range 410-4130). Of the survivors, 37 (17%) medically treated @entity3166 @entity1 developed a post- @entity3166 strictures versus 27 surgically treated @entity3166 @entity1 (24%; p=0.001). Highest @entity1851 ( @entity1851 ) level measured during the @entity3166 episode was associated with the development of post- @entity3166 strictures (OR 1.20, 95% confidence interval 1.11-1.32; p=0.03). No post- @entity3166 strictures were detected in @entity1 with @entity1851 levels <46mg/L. CONCLUSION: This multicenter retrospective cohort study demonstrates an overall incidence of clinical relevant post- @entity3166 strictures of 19%, with a higher rate (24%) in @entity3166 cases treated surgically. Increased @entity1851 levels during the @entity3166 episode were associated with the development of post- @entity3166 strictures.

Risk factors associated with postnecrotizing enterocolitis strictures in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3166 :: ('MESH:D020345', 'Disease') :: ['NEC', 'necrotizing enterocolitis'] @entity1851 :: ('1401', 'Gene') :: ['C-reactive protein', 'CRP']
@entity1 :: (9606,Species) :: ['infants']
