Adequate indoor-air quality (IAQ)-defined by the temperature, relative humidity, and the levels of @entity544 , small particles, and total volatile organic compounds (TVOC)-is crucial in laboratory animal facilities. The ventilation standards for controlling these parameters are not well defined. This study assessed the effect of 2 ventilation strategies on IAQ in 2 rooms housing @entity2608 ( @entity2608 ). We hypothesized that using a demand-controlled ventilation ( @entity14637 ) system with a baseline ventilation rate of less than 3 @entity11535 ( @entity11535 ) would maintain IAQ comparable to or better than the traditional constant flow rate (CFR) system at 12 fresh @entity11535 . During a 60-d study period, each of the 2 rooms operated 30 d on @entity14637 and 30 d on CFR ventilation. In both rooms, temperatures remained more consistently within the established setpoint during the @entity14637 phase than during the CFR phase. Relative humidity did not differ significantly between rooms or strategies. @entity3158 was lower during the CFR phase than @entity14637 phase. Small-particle and TVOC levels were lower during CFR in the larger (3060 ft(3)) room but not the smaller (2340 ft(3)) room. During the @entity14637 phase, the larger room was at the baseline airflow rate over 99% of the time and the smaller room over 96% of the time. The @entity14637 strategy resulted in a baseline airflow rate of less than 3 @entity11535 , which in turn provided acceptable IAQ over 96% of the time; higher ventilation rates were warranted only during sanitation periods.

Comparison of Indoor Air Quality between 2 Ventilation Strategies in a Facility Housing XXXX ( @entity2608 ).

@entity3158 :: ('D002245', 'Chemical') :: ['CO2'] @entity11535 :: ('MESH:D009041', 'Disease') :: ['fresh-air changes per hour', 'ACH'] @entity544 :: ('MESH:D002245', 'Chemical') :: ['carbon dioxide'] @entity2608 :: ('9544', 'Species') :: ['Macaca mulatta', 'rhesus macaques'] @entity14637 :: ('64279', 'Species') :: ['DCV']
@entity2608 :: (9544,Species) :: ['Rhesus Macaques']
