BACKGROUND: To analyze the clinical impact derived from endovascular treatment failure on @entity1 with @entity432 ( @entity432 ) regarding their preoperative clinical stage. METHODS: Retrospective review for primary endovascular procedures for @entity432 from 2008 to 2013. Primary end point included clinical deterioration defined as @entity63 ( @entity63 ) or clinical worsening by, at least, one Rutherford's classification category, related to procedure's failure (restenosis >70% or occlusion). RESULTS: Ninety procedures were analyzed in 85 @entity1 , 87.8% operated due to @entity63 . The lesion treated was classified as Trans-Atlantic Inter-Society Consensus (TASC)-A/B in 76.7%, with a mean length of 98.5      54  mm. Covered stent graft (SG) was used in 31.1% of the cases. Median follow-up was 14.5  months and treatment failure occurred in 33.3% of cases (n  =  30, 9 restenosis and 21 occlusions). Clinical worsening was assessed in 40% of treatment failures and 6 of 21 (28.6%) presented as @entity63 . Twenty-two major adverse limb events (MALEs) were recorded and 8 major amputations. Regarding the type of stent, more occlusions were recorded on @entity1 treated with SG compared with bare metal stent (39.3% vs. 16%; P  =  0.02). However, no differences were found between groups regarding clinical worsening attributable to treatment failure (HR, 1.33; CI 95%, 0.5-3.5; P  =  0.5). On multivariate analysis, TASC-C/D lesions (HR, 5.5; CI 95%, 2.3-13.3; P  <  0.001) and female sex (HR, 4.9; CI 95%, 1.9-12.5; P  =  0.001) behaved as significant predictors for failure and dual-antiplatelet therapy as a protective factor (HR, 0.3; CI 95%, 0.3-0.13; P  =  0.03). No predictors were obtained regarding clinical worsening and occurrence of MALEs in our series. CONCLUSIONS: @entity1 with failure of endovascular procedures on @entity432 appeared with clinical worsening in a no negligible number of cases in our sample regarding their preoperative clinical situation. Thus, we believe that endovascular treatment should be carefully deliberated.

Clinical Outcomes after Endovascular Treatment Failure in @entity1 with XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity432 :: ('MESH:D001157', 'Disease') :: ['femoropopliteal occlusive disease', 'FPOD'] @entity63 :: ('MESH:D007511', 'Disease') :: ['acute limb ischemia', 'ALI', 'critical limb ischemia']
@entity432 :: (MESH:D001157,Disease) :: ['Femoropopliteal Occlusive Disease']
