In the clinical grounds, @entity1 with >= 90  % luminal narrowing during @entity934 ( @entity1617 ) testing had variable response. We investigated @entity63 findings and chest symptoms in @entity1 with >= 90  % luminal narrowing when performing ACh tests, retrospectively. We performed 763 ACh tests over 13  years (2001-2013). We analyzed chest symptoms and positive @entity63 ECG changes during ACh tests. More than 90  % luminal narrowing was found in 441 @entity1 (57.8  %) including 355 @entity1 in the right coronary artery (RCA) and 363 @entity1 in the left coronary artery (LCA). Chest symptom was observed in 386 @entity1 (87.5  %) including 293 @entity1 in the RCA and 304 @entity1 in the LCA. ST elevation was found in 161 @entity1 including 110 in the RCA and 85 @entity1 in the LCA, @entity308 was recognized in 146 @entity1 including 119 @entity1 in the RCA and 117 @entity1 in the LCA. Three quarter of @entity1 with >= 90  % luminal narrowing had significant @entity63 ECG changes, whereas two-third of @entity1 with >= 90  % luminal narrowing complained usual chest @entity158 accompanied with significant @entity63 ECG changes. Unusual chest symptom was complained in 7.3  % @entity1 with >= 90  % luminal narrowing. Neither chest symptom nor ECG changes were found in 30 @entity1 (6.8  %) with >= 90  % luminal narrowing. A third of these @entity1 had @entity63 findings on non-invasive tests before catheterization and six @entity1 had @entity432 . We should realize some limitation to define positive coronary @entity2473 based on the @entity63 ECG change and chest symptom during ACh tests.

@entity2473 on @entity934 @entity2473 provocation tests: comparison of clinical positive XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity308 :: ('MESH:D003866', 'Disease') :: ['while ST depression'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity1617 :: ('CHEBI:22614', 'Chemical') :: ['ACh'] @entity2473 :: ('MESH:D013035', 'Disease') :: ['spasm'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity432 :: ('MESH:D001157', 'Disease') :: ['subtotal or total occlusion'] @entity934 :: ('MESH:D000109', 'Chemical') :: ['acetylcholine']
@entity2473 :: (MESH:D013035,Disease) :: ['spasm']
