INTRODUCTION: Learning capacity may influence an individual's response to @entity2026 rehabilitation. However, investigations into the relationship between novel word learning ability and response to @entity5547 therapy are lacking. The aim of the present study was to evaluate the novel word learning ability in post- @entity64 @entity2026 and to establish the relationship between learning ability and @entity5547 treatment outcomes. We also explored the influence of locus of language breakdown on novel word learning ability and @entity5547 treatment response. MATERIAL AND METHODS: 30 adults (6F; 24M) with chronic, post- @entity64 @entity2026 were recruited to the study. Prior to treatment, @entity1 underwent an assessment of language, which included the @entity1650 Test and three baseline confrontation naming probes in order to develop sets of treated and untreated items. We also administered the novel word learning paradigm, in which @entity1 learnt novel names associated with unfamiliar objects and were immediately tested on recall (expressive) and recognition (receptive) tasks. @entity1 completed 48h of Aphasia Language Impairment and Functioning Therapy (Aphasia LIFT) over a 3 week (intensive) or 8 week (distributed) schedule. Therapy primarily targeted the remediation of word @entity51 , so naming of treated and untreated items immediately post-therapy and at 1 month follow-up was used to determine therapeutic response. RESULTS: Performance on recall and recognition tasks demonstrated that @entity1 were able to learn novel words; however, performance was variable and was influenced by @entity1 ' @entity2026 severity, lexical-semantic processing and locus of language breakdown. Novel word learning performance was significantly correlated with @entity1 ' response to therapy for treated items at post-therapy. In contrast, @entity1 ' novel word learning performance was not correlated with therapy gains for treated items at 1 month follow-up or for untreated items at either time point. Therapy intensity did not influence treatment outcomes. DISCUSSION: This is the first group study to directly examine the relationship between novel word learning and therapy outcomes for @entity5547 rehabilitation in adults with @entity2026 . Importantly, we found that novel word learning performance was correlated with therapy outcomes. We propose that novel word learning ability may contribute to the initial acquisition of treatment gains in @entity5547 rehabilitation.

The relationship between novel word learning and @entity5547 treatment success in adults with chronic XXXX .

@entity1 :: ('9606', 'Species') :: ['participants', 'Participants'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity1650 :: ('MESH:D001308', 'Disease') :: ['Comprehensive Aphasia'] @entity51 :: ('MESH:D009461', 'Disease') :: ['retrieval deficits'] @entity2026 :: ('MESH:D001037', 'Disease') :: ['aphasia'] @entity5547 :: ('MESH:D000849', 'Disease') :: ['anomia']
@entity2026 :: (MESH:D001037,Disease) :: ['aphasia']
