Abstract Objective. @entity827 ( @entity827 ) is the most common form of @entity8649 . We aimed to evaluate the small bowel mucosa by capsule endoscopy (CE) in @entity827 @entity1 for investigation of other possible causes of @entity490 . Material and methods. The study group consisted of 41 @entity1 with @entity827 . A standard questionnaire was used to record the gastrointestinal symptoms, other clinical findings, Mediterranean @entity221 gene ( @entity16498 ) mutations, and history of medications including non-steroidal anti-inflammatory drugs (NSAIDs). Gastroscopy, colonoscopy and small bowel CE were performed in all @entity1 , and biopsies were taken from terminal ileum and duodenum. Results. The mean age of the @entity1 was 34    11 years, 63% of them were female, and 76.5% of them were carrying @entity16498 exon 10 mutations. Only one @entity1 used NSAIDs in addition to @entity3812 . In endoscopic investigations, @entity356 was detected in only one @entity1 , and no significant findings were detected in colonoscopy. CE showed small bowel @entity33 in 44% ( @entity2681 in 26.8%, @entity1066 in 17.1%) and @entity4 in 29.3% of the @entity1 . Most (64%) of the @entity1066 and @entity2681 were localized to jejunum, and only 24% were in ileum. Mitotic changes as an indirect finding of @entity3812 @entity137 were not different from the changes observed in samples of independent group of @entity1 with @entity1744 . Conclusion. Mucosal defect was observed in half of the @entity827 @entity1 , which may be associated with underlying @entity32 or chronic @entity3812 exposure. Detection of nonspecific @entity32 without mitotic changes supports that @entity33 may be associated with the autoinflammatory process.

Small bowel mucosal damage in XXXX : results of capsule endoscopy screening.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity32 :: ('MESH:D007249', 'Disease') :: ['chronic inflammation', 'inflammation'] @entity16498 :: ('4210', 'Gene') :: ['MEFV'] @entity137 :: ('MESH:D064420', 'Disease') :: ['toxicity'] @entity827 :: ('MESH:D010505', 'Disease') :: ['Familial Mediterranean fever', 'FMF'] @entity2681 :: ('MESH:D014077', 'Disease') :: ['erosions'] @entity4 :: ('MESH:D004487', 'Disease') :: ['edema'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer'] @entity33 :: ('MESH:D052016', 'Disease') :: ['mucosal defects'] @entity1744 :: ('MESH:D043183', 'Disease') :: ['irritable bowel syndrome'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity3812 :: ('MESH:D003078', 'Chemical') :: ['colchicine'] @entity8649 :: ('MESH:D056660', 'Disease') :: ['autoinflammatory diseases'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric erosion']
@entity827 :: (MESH:D010505,Disease) :: ['familial Mediterranean fever']
