OBJECTIVE: This study aimed to investigate the role of endothelial progenitor cells (EPCs) in transplantation in @entity35 with @entity295 induced by endotoxins (lipopolysaccharides, @entity558 ). METHODS: EPCs of @entity35 were isolated, cultured, and identified. EPCs were fluorescently labeled with the green fluorescent protein adenoviral transfection method. The @entity35 were divided into normal control group (NC group), endothelial progenitor cell transplantation control group (EPC group), @entity295 model group ( @entity558 group), and endothelial progenitor cell transplantation treatment group ( @entity558 +EPC group). The @entity295 model was established by intravenous delivery of @entity558 . Two EPC transplantation groups were injected with a fluorescently labeled EPC suspension via the tail vein. One day and 7 days after transplantation, lung, liver, and kidney tissues were obtained to detect the wet/dry ratio (W/D) and perform @entity1710 and @entity1711 (HE) staining. An ELISA assay was used to detect cytokines @entity568 and @entity13358 . Real-time polymerase chain reaction was used to detect @entity7942 mRNA expression in lung, liver, and kidney tissues. RESULTS: EPC transplantation can significantly reduce lung, liver, and kidney tissue damage and W/D ratios in septic @entity35 , downregulate @entity7942 mRNA expression, and reduce @entity568 and @entity13358 levels. CONCLUSION: EPC transplantation can significantly alleviate lung, liver, and kidney tissue damage.

Role of Endothelial Progenitor Cell Transplantation in XXXX With @entity295 .

@entity558 :: ('MESH:C536528', 'Disease') :: ['LPS'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity13358 :: ('25325(Tax:10116)', 'Gene') :: ['IL-10'] @entity1711 :: ('MESH:D004801', 'Chemical') :: ['eosin'] @entity568 :: ('24498(Tax:10116)', 'Gene') :: ['interleukin (IL)-6', 'IL-6'] @entity1710 :: ('MESH:D006416', 'Chemical') :: ['hematoxylin'] @entity35 :: ('10116', 'Species') :: ['Sprague-Dawley rats', 'rats'] @entity7942 :: ('29260(Tax:10116)', 'Gene') :: ['TLR4']
@entity35 :: (10116,Species) :: ['Rats']
