BACKGROUND: Lateral neck @entity1600 ( @entity1600 ) metastases (N1b) have been identified as independent risk factors of recurrence in @entity1 with @entity3557 ( @entity3557 ). OBJECTIVE: This study aimed to determine the predictive factors of recurrence in N1b @entity3557 @entity1 and to clarify the postoperative event patterns. METHODS: All @entity1 who underwent operation for N1b @entity3557 between 1978 and 2012 were reviewed. The median follow-up period was 6.5  years. RESULTS: In total, 344 N1b @entity1 were included. Twenty-four @entity1 (7%) were lost to long-term follow-up. Among the remaining 320 @entity1 , the mean (  SD) follow-up time was 8.9      8.8  years (median, 6.5; range, 2-36.4). Eighty-two @entity1 (26%) presented with @entity1600 recurrence (LR). Multivariate analyses showed that @entity1600 metastases with extracapsular extension and the @entity1600 ratio (ratio between the number of N1 and number of resected @entity1600 ) in the lateral compartment were independent predictors of recurrent disease. The median time to reoperation was 19  months (range, 3-173), with 79% of reoperations occurring within 2  years after the initial thyroidectomy. Reoperations for LR (75 @entity1 ) were performed in 76% of the @entity1 with a focused minimal access approach or selective @entity1600 dissection. After curative reoperative surgery for recurrence, complications occurred in 6 @entity1 (8%), including a 1% permanent complication rate. CONCLUSION: Extranodal extension of @entity1600 metastases and the @entity1600 ratio in the lateral compartment are prognostic factors for recurrence. In most cases, reoperation for LR can be performed with a focused minimal access approach, with a low morbidity rate.

Recurrence of XXXX with lateral cervical node metastases: Predictive factors and operative management.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1600 :: ('MESH:D014388', 'Disease') :: ['LN', 'lymph node'] @entity3557 :: ('MESH:C536915', 'Disease') :: ['papillary thyroid carcinoma', 'PTC']
@entity3557 :: (MESH:C536915,Disease) :: ['papillary thyroid carcinoma']
