PURPOSE: To evaluate the clinical utility of optical coherence tomography angiography (OCTA) in @entity1 with @entity2994 ( @entity2994 ), and to systematically compare OCTA images with changes seen on color fundus photography and @entity941 angiography (FA). DESIGN: Reliability analysis. METHODS: Eighty-one eyes of 76 @entity1 with a history of @entity2994 (branch, central, or hemicentral), both acute and chronic, underwent OCTA and color fundus photography. In 29 eyes, data were compared to FA imaging. Comparative and multimodal analysis of the 3 imaging procedures were performed. RESULTS: We identified good agreement between FA and OCTA scans centered on the macula for capillary nonperfusion (intraclass correlation coefficient [ICC] 0.825 for the 3  * 3-mm scan and 0.891 for the 8  * 8-mm scan). Agreement for area of capillary changes (dilation, pruning, and @entity8721 ) was also substantial (ICC 0.712 for the 3  * 3-mm scan and 0.787 for the 8  * 8-mm scan). For foveal avascular zone grading, agreement was good for the 3  * 3-mm scan (kappa  = 1.000 for radius and kappa  = 0.799 for outline) but poor for the 8  * 8-mm scan (kappa  = 0.156 for radius and kappa  = 0.600 for outline). The quality of the images obtained was an important issue for OCTA, as 15.1% of scans were nongradable, particularly in @entity1 unable to maintain fixation. CONCLUSIONS: OCTA is a quick, reliable, and noninvasive method to evaluate the area of capillary nonperfusion and foveal avascular zone morphology in @entity1 with @entity2994 . However, good fixation is a requirement for acquisition of good-quality images.

Systematic Evaluation of Optical Coherence Tomography Angiography in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2994 :: ('MESH:D012170', 'Disease') :: ['retinal vein occlusion', 'RVO'] @entity8721 :: ('MESH:D013684', 'Disease') :: ['telangiectasia'] @entity941 :: ('MESH:D019793', 'Chemical') :: ['fluorescein']
@entity2994 :: (MESH:D012170,Disease) :: ['Retinal Vein Occlusion']
