OBJECTIVES: To assess the clinical characteristics, pathology, and long-term follow-up of @entity1 with bilateral @entity703 (BNFRTs). METHODS: @entity1 with BNFRTs and @entity5 were identified from a prospective surgery database. The Mann-Whitney U test, Cox proportional hazards regression analysis, and the log-rank test were used to compare groups. RESULTS: From a database of 1082 @entity1 with nonmetastatic @entity703 , 46 were identified with BNFRTs (4.25%). Thirty-three had @entity5 and 13 had @entity5 . The median @entity1 age of BNFRT @entity1 was 61 years. Of the 92 @entity703 in these 46 @entity1 , 42% were managed with radical nephrectomy (RN) and 58% with @entity1625 ( @entity1625 ); 7 underwent bilateral @entity1625 . The @entity5 were @entity1358 in 66% (n = 61), @entity1377 in 14% (n = 13), and the remaining 20% were of varied histologic origin. A 76.2% concordance was noted between the histologic subtypes of the two @entity703 in each @entity1 . Median follow-up was 74 months. Thirty-three @entity1 (72%) were disease-free and 7 @entity1 had recurrence (2 local, 5 metastatic). Compared with @entity1 having unilateral disease, BNFRT @entity1 had an equivalent disease-free survival (DFS) (bilateral: 3-year DFS 90%, 5-year DFS 83%; unilateral: 3-year DFS 92%, 5-year DFS 82% [P = 0.449]). No difference in DFS was observed between synchronous and @entity5 . CONCLUSIONS: BNFRTs were present in 4.25% of @entity1 with @entity703 . Conventional clear cell histology was the most common histologic subtype; concordance among @entity5 was found to be 76%. DFS rates comparable to those of @entity5 can be obtained by using combinations of @entity1625 and RN.

Long-term follow-up of bilateral XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'patient'] @entity1377 :: ('MESH:D002291', 'Disease') :: ['papillary carcinoma'] @entity1625 :: ('MESH:D004828', 'Disease') :: ['PN', 'partial nephrectomy'] @entity5 :: ('MESH:D009369', 'Disease') :: ['synchronous tumors', 'asynchronous tumors', 'tumors', 'unilateral tumors'] @entity1358 :: ('MESH:D002292', 'Disease') :: ['conventional clear cell carcinoma'] @entity703 :: ('MESH:D007680', 'Disease') :: ['renal tumors', 'nonfamilial renal tumors', 'sporadic renal tumors']
@entity703 :: (MESH:D007680,Disease) :: ['sporadic renal tumors']
