BACKGROUND: A prospective 1-year study was conducted to assess the frequency, clinical spectrum, histologic description, and follow-up of @entity7592 unrelated to ingestion of caustic or corrosive agents. METHODS: The diagnosis of @entity7592 was based on a diffusely black esophagus at endoscopy and typical histologic features of @entity39 . Ingestion of caustic and corrosive agents was excluded in all @entity1 . Medical history, associated diseases, and clinical symptoms were recorded for each @entity1 . Nutritional status was evaluated based on clinical and biochemical parameters. Treatment included short-term parenteral nutrition and intravenous administration of a pump proton inhibitor. A second endoscopy was performed when possible at 2 weeks after presentation to assess regression of @entity7592 . RESULTS: Among 3900 @entity1 who underwent EGD, 8 (0.2%) with @entity7592 were identified. Nutritional status was poor for 6 @entity1 . Complete resolution of @entity7592 without further recurrence was observed in 4. No esophageal strictures appeared during follow-up. Four @entity1 died, but no death was directly related to @entity7592 . CONCLUSION: Acute @entity39 is not as infrequent an endoscopic finding as has been reported. Acute @entity39 appears to be associated with poor general health status and is not a purely local phenomenon.

Acute XXXX : a 1-year prospective study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity7592 :: ('MESH:D015882', 'Disease') :: ['acute esophageal necrosis'] @entity39 :: ('MESH:D009336', 'Disease') :: ['esophageal necrosis', 'diffuse mucosal and submucosal necrosis']
@entity39 :: (MESH:D009336,Disease) :: ['esophageal necrosis']
