OBJECTIVE: To evaluate the therapeutic effects of probiotics on @entity4837 and the safety. METHODS: Sixty-eight neonates with @entity1087 were divided into a control group and a treatment group (n=34) randomly, and treated by blue light phototherapy and that in combination with probiotics. The serum @entity648 levels were detected before and 1, 4, 7 days after treatment. The time when therapy showed effects and @entity1087 faded, clinical outcomes as well as adverse reactions were recorded. The categorical data were expressed as (  s) and compared by t test. The numerical data were expressed as (case, %) and compared by      test. P<0.05 was considered statistically significant. RESULTS: Serum @entity648 levels of the two groups were similar before treatment (P>0.05). The levels significantly decreased 1, 4 and 7 days after treatment (P<0.05), but there was no significant inter-group difference on the post-treatment 1st day (P>0.05). The treatment group underwent more significant decreases on the 4th and 7th days than the control group did (P=0.002, 0.001). In the treatment group, the therapy exerted effects on (1.0  0.5) d and @entity1087 faded on (3.8  1.7) d, which were (2.6  0.6) d and (5.3  2.1) d respectively in the control group (P=0.001, 0.002). The effective rate of the treatment group significantly exceeded that of the control group (P=0.002). There were no obvious adverse reactions in either group. CONCLUSIONS: Probiotics lowered the serum @entity648 levels of neonates with @entity1087 rapidly, safely and significantly, and accelerated @entity1087 fading as well. This method is worthy of application in clinical practice.

Therapeutic effects of probiotics on XXXX .

@entity648 :: ('MESH:D001663', 'Chemical') :: ['bilirubin'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity4837 :: ('MESH:D007567', 'Disease') :: ['neonatal jaundice']
@entity4837 :: (MESH:D007567,Disease) :: ['neonatal jaundice']
