BACKGROUND: Autoantibodies or antibodies against self-antigens are produced either during physiological processes to maintain homeostasis or pathological process such as @entity130 and @entity281 . Infection with parasites including @entity31365 has been shown to generally induce elevated self-antibody (autoantibody) levels. @entity31365 is increasingly recognized as one of the most important emerging @entity1 @entity311 in Southeast Asia that can cause severe @entity281 leading to mortality. Autoimmune-like phenomena have been hypothesized to play a role in the protective immune responses in @entity281 . METHODS: We studied the autoantibody profile from serum of eleven @entity1 diagnosed with @entity31365 . Autoantigen arrays were used to elucidate the autoantibody repertoire of @entity31365 infected @entity1 . The patented OGT Discovery Array with 1636 correctly folded antigen was employed. RESULTS: Analysis of the @entity1 versus control sera gave us 24 antigens with high reactivity with serum antibodies. CONCLUSIONS: Understanding the autoantibody profile of malarious @entity1 infected with @entity31365 would help to further understand the host-parasite interaction, host immune response and disease pathogenesis. These reactive antigens may serve as potential biomarkers for cases of asymptomatic @entity311 and mild @entity311 or predictive markers for severe @entity311 .

Autoantibody profile of XXXX infected with knowlesi @entity311 .

@entity1 :: ('9606', 'Species') :: ['human', 'patients', 'patient'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infection', 'malaria infection'] @entity311 :: ('MESH:D008288', 'Disease') :: ['malaria'] @entity31365 :: ('5850', 'Species') :: ['Plasmodium', 'Plasmodium knowlesi', 'P. knowlesi'] @entity130 :: ('MESH:D014947', 'Disease') :: ['trauma']
@entity1 :: (9606,Species) :: ['patients']
