In the Western world the percentage of subjects over the age of 60 years is rapidly increasing. Therefore, elderly individuals represent a progressively increasing proportion of @entity1 with @entity741 ( @entity741 ), which is the most prevalent disease in this age range. In the elderly both the clinical presentation and the outcome of @entity741 have some peculiar features which may have important therapeutic implications. The prevalence of both @entity453 and uncomplicated angina pectoris increases up to the sixth decade when it reaches a plateau. Conversely, the prevalence of @entity583 increases progressively at increasing ages without reaching any plateau at all. These findings indicate that the higher prevalence of @entity583 in the elderly is not caused by a worsening of the @entity731 background, but rather by a greater prevalence and/or severity of the functional factors such as local smooth muscle hyperreactivity, local thrombotic stimuli and alterations of the systemic @entity715 -thrombolysis equilibrium which are more directly responsible for the irreversible occlusion of a coronary artery branch. Therefore, the prevention of @entity741 in the elderly should focus mainly on the ischemic stimuli leading to coronary @entity715 rather than on the @entity731 background. Another important feature of @entity741 in the elderly is the high short and medium-term mortality of acute @entity583 . This excess of mortality is caused mainly by a much higher incidence of @entity7086 , which does not appear to be related to the severity of @entity453 nor to the @entity1188 size.(ABSTRACT TRUNCATED AT 250 WORDS)

[Morphofunctional changes in the left ventricle of the elderly XXXX and the vulnerability to myocardial necrosis].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity7086 :: ('MESH:D006341', 'Disease') :: ['cardiac rupture'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarct'] @entity741 :: ('MESH:D017202', 'Disease') :: ['IHD', 'ischemic heart disease'] @entity453 :: ('MESH:D003324', 'Disease') :: ['coronary atherosclerosis'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis']
@entity1 :: (9606,Species) :: ['person']
