The current trend is to allow @entity66 ( @entity66 ) @entity1 to introduce oats to their gluten free diet. We sought further data from the clinical setting with regards to oats consumption by coeliac @entity1 . Several oat products were tested for @entity3505 contamination using a commercial enzyme linked immunoassay (ELISA) kit, and six samples were examined by an ELISA using a cocktail of monoclonal antibodies, mass spectrometry, and western blot analysis. Nineteen adult @entity66 @entity1 on a gluten free diet were challenged with 50 g of oats per day for 12 weeks. Serological testing and gastroduodenoscopy was performed before and after the challenge. Biopsies were scored histologically and levels of mRNA specific for @entity379 were determined by reverse transcription-polymerase chain reaction analysis. Oats were well tolerated by most @entity1 but several reported initial abdominal discomfort and bloating. One of the @entity1 developed @entity194 and a @entity1910 during the first oats challenge. She subsequently improved on an oats free diet but developed @entity194 and @entity1909 during a second challenge. Five of the @entity1 showed positive levels of @entity379 mRNA after challenge. Some concerns therefore remain with respect to the safety of oats for coeliacs.

Oats induced @entity194 in XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['coeliac disease', 'CD'] @entity1910 :: ('MESH:D005076', 'Disease') :: ['rash'] @entity379 :: ('3458', 'Gene') :: ['interferon gamma'] @entity194 :: ('MESH:D001284', 'Disease') :: ['subtotal villous atrophy', 'partial villous atrophy'] @entity3505 :: ('4565', 'Species') :: ['wheat'] @entity1909 :: ('MESH:D003872', 'Disease') :: ['dramatic dermatitis']
@entity66 :: (MESH:D004194,Disease) :: ['coeliac disease']
