Fifteen compounds were extracted and purified from the leaves of @entity16666 . cv. Rosa-plena. These compounds include liriodenine (1), lysicamine (2), (-)-anonaine (3), (-)-asimilobine (4), (-)-caaverine (5), (-)-N-methylasimilobine (6), (-)-nuciferine (7), (-)-nornuciferine (8), (-)-roemerine (9), 7-hydroxydehydronuciferine (10) cepharadione B (11), b-sitostenone (12), stigmasta-4,22-dien-3-one (13) and two chlorophylls: pheophytin-a (14) and aristophyll-C (15). The anti-oxidation activity of the compounds was examined by antiradical scavenging, metal chelating and ferric reducing power assays. The results have shown that these compounds have antioxidative activity. The study has also examined the antiproliferation activity of the isolated compounds against @entity1 @entity320 , prostate and @entity356 cells. The results shown that 7-hydroxydehydronuciferine (10) significantly inhibited the proliferation of @entity320 , prostate and @entity356 cells. Together, these findings suggest that leaves of @entity16666 . cv. Rosa-plena are a good resource for obtaining the biologically active substances with antioxidant properties.

Antioxidant and anticancer aporphine alkaloids from the leaves of XXXX . cv. Rosa-plena.

@entity1 :: ('9606', 'Species') :: ['human'] @entity16666 :: ('4432', 'Species') :: ['Nelumbo nucifera Gaertn'] @entity356 :: ('MESH:D013274', 'Disease') :: ['gastric cancer'] @entity320 :: ('MESH:D008545', 'Disease') :: ['melanoma']
@entity16666 :: (4432,Species) :: ['Nelumbo nucifera Gaertn']
