OBJECTIVE: Modes of treatment for @entity704 remain controversial. The aim of this study is to analyse the early and long-term results of surgical intervention for this condition. METHODS: Between 1972 and 2008, 43 out of 315 @entity1 , who underwent resection with radical intent for @entity704 , subsequently relapsed. Of these, 30 cases were deemed suitable for resection and operation, and were surgically treated. The remaining 13 were treated with radio- and/or chemotherapy (RT/CT). Overall outcomes for long-term survival up to 5 years (LTS) and disease-free survival (DFS) were analysed using standard statistics. RESULTS: The average age of the relapsed @entity1 was 54.7  12.7 years. There were 21 males and 22 females. Forty out of the 43 had @entity1737 ( @entity1737 ). Fifteen cases concerned a single detected relapse lesion. Among the 43 @entity1 , relapses were found in the following sites: pleura (25 cases), mediastinum (12), lung (five), liver and bone (one). The perioperative mortality was 0% and the morbidity was 27%. Twenty-two of the surgically treated @entity1 had complete resection; their LTS was 77% and DFS was 71%. Those @entity1 who underwent surgery had significantly better outcomes compared with @entity1 treated with radio- and/or chemotherapy (LTS only 35%; hazard ratio (HR): 0.22; 95% confidence interval (CI): 0.08-0.59; p=0.001). Complete repeated resection yielded much better outcomes than partial resection (LTS 91% vs 31%, p<0.001), whereas incomplete resection was associated, as one might expect, with a poor prognosis (HR: 6.12; 95% CI: 1.18-31.55; p=0.031). No evidence for an association with other clinical, surgical and pathological characteristics was found with regard to LTS or DFS. CONCLUSIONS: Surgical resection is recommended for the treatment of @entity704 , provided that criteria for suitability for resection/operation are satisfactory at the time of diagnosis. Best survival outcomes are found to depend on the degree of @entity1939 .

Single-centre 40-year results of redo operation for recurrent XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1939 :: ('MESH:D001766', 'Disease') :: ['completeness of the repeat resection'] @entity1737 :: ('MESH:D009157', 'Disease') :: ['MG', 'myasthenia gravis'] @entity704 :: ('MESH:D013945', 'Disease') :: ['recurrent thymoma', 'thymoma']
@entity704 :: (MESH:D013945,Disease) :: ['thymomas']
