INTRODUCTION: The objective of the study to is to determine the characteristics associated with endotracheal intubation in @entity326 @entity1 . METHODS: This is a post hoc analysis of the database of the SEPSISPAM study, including @entity1 with @entity326 . RESULTS: Among the 776 @entity1 , 633 (82%) were intubated within 12 hours of study inclusion (early intubation), 113 (15%) were never intubated, and 30 (4%) had delayed intubation. Intensive care units (ICUs) were classified according to frequency of early intubation: early intubation less than 80% of @entity1 (lowest frequency: 7 ICUs, 254 @entity1 ), 80% to 90% (middle frequency: 5 ICUs, 170 @entity1 ), and greater than 90% (highest frequency: 6 ICUs, 297 @entity1 ). Type of ICU, @entity358 , lactate greater than 2 mmol/L, lower Pao2/fraction of inspired @entity26 ratio, lower Glasgow score, and absence of immunosuppression were independently associated with early intubation. @entity1 never intubated had a lower initial severity and a low mortality rate. In comparison to @entity1 intubated early, @entity1 with delayed intubation had had fewer days alive without organ support by day 28. Intensive care units with the highest frequency of early intubation had a higher mortality rate in comparison to ICUs with middle frequency of early intubation. A nonsignificant increased mortality was observed in ICU with lowest frequency of early intubation. CONCLUSIONS: Practices regarding the place of endotracheal intubation in @entity326 may impact outcome.

Impact of endotracheal intubation on XXXX outcome: A post hoc analysis of the SEPSISPAM trial.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary infection'] @entity326 :: ('MESH:D012772', 'Disease') :: ['septic shock']
@entity326 :: (MESH:D012772,Disease) :: ['septic shock']
