1. The effect of @entity18398 and @entity3163 on swelling- and @entity8816 ( @entity17462 )-stimulated KCl cotransport was examined in blood cells from homozygote sickle cell @entity417 @entity1 . 2. Blood was drawn into heparin or @entity1098 by vein puncture from sickle cell @entity1 previously diagnosed in the haematology clinics of Princess Badee'a Teaching Hospital. A standard method for measuring flux by using radioactive @entity12310 was used. 3. @entity18398 strongly inhibited swelling-stimulated KCl cotransport if added before swelling. @entity18398 and @entity3163 added before @entity17462 inhibited the activation of transport by @entity17462 . @entity18398 added after @entity17462 did not inhibit transport. 4. The inhibition of the effects of @entity17462 by @entity18398 and @entity3163 indicates that activation of the flux by @entity17462 requires the action of phosphatase.

Inhibition of K+ transport in @entity1 sickle cell erythrocytes by @entity18398 and XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3163 :: ('MESH:D012969', 'Chemical') :: ['sodium fluoride'] @entity417 :: ('MESH:D000740', 'Disease') :: ['anaemia'] @entity8816 :: ('MESH:D005033', 'Chemical') :: ['N-ethylmaleimide'] @entity12310 :: ('MESH:D012413', 'Chemical') :: ['rubidium'] @entity18398 :: ('MESH:D019319', 'Chemical') :: ['okadaic acid', 'Okadaic acid'] @entity1098 :: ('MESH:D004492', 'Chemical') :: ['EDTA'] @entity17462 :: ('CHEBI:44485', 'Chemical') :: ['NEM']
@entity3163 :: (MESH:D012969,Chemical) :: ['sodium fluoride']
