BACKGROUND: @entity2791 ( @entity2791 ) is a cause of @entity454 . We studied the effect of percutaneous renal artery intervention (PRI) in @entity1 with advanced, progressive disease at risk for @entity177 , hypothesizing a beneficial effect. METHODS: Thirty-nine primary and 14 secondary PRIs were performed on 28 @entity1 with @entity731 @entity2791 , serum @entity1011 >300 micromol/L, and progressive loss of renal function >/=1 year before PRI. Renal function and RA patency were prospectively followed for 12 months after primary and secondary PRI. The intervention's effect on the progressive loss of renal function was calculated by comparing reciprocal slopes of serum @entity1011 against time before and after PRI. RESULTS: Progression of @entity177 slowed significantly following PRI. Mean (+/-SE) slopes of reciprocal serum @entity1011 values were: 6.69 +/- 0.97 L micromol(-1) day(-1) (x10(-6)) before and 6.76 +/- 3.03 L micromol(-1) day(-1) (x10(-6)) after PRI (P= 0.0007). Fifteen @entity1 (53.5%) showed improvement or stabilization of progressive @entity8 . Out of 11 @entity1 expected to become dialysis dependent within one year, 8 (72.7%) experienced an improvement in renal function sufficient to remain dialysis-free. Favorable outcome correlated with a lower @entity1011 level (P= 0.0137) and a more negative slope of progression (r= 0.49, P= 0.020) at entry. Mortality was 10.7%, and rate of local complications was 7.1%. @entity177 following PRI was suspected in 17.9% of @entity1 . CONCLUSION: PRI may improve renal function and ultimately delay dialysis in @entity1 with @entity177 . Possible advantages must be weighed against the risk of @entity177 advancement and high procedure-related complication rate.

Delay of dialysis in XXXX : prospective study on percutaneous renal artery interventions.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity8 :: ('MESH:D007674', 'Disease') :: ['renal dysfunction'] @entity2791 :: ('MESH:D012078', 'Disease') :: ['Renal artery stenosis', 'RAS'] @entity177 :: ('MESH:D051437', 'Disease') :: ['advanced renal failure', 'renal failure', 'Deterioration of renal function'] @entity1011 :: ('MESH:D003404', 'Chemical') :: ['creatinine'] @entity731 :: ('MESH:D050197', 'Disease') :: ['atherosclerotic'] @entity454 :: ('MESH:D007676', 'Disease') :: ['end-stage renal failure']
@entity454 :: (MESH:D007676,Disease) :: ['end-stage renal failure']
