BACKGROUND: High birthweight is a potential risk factor for childhood @entity1313 , particularly @entity816 . We investigated several birth characteristics in relationship to @entity1313 in young @entity1 . METHODS: We obtained 849 invasive central nervous system (CNS) @entity5 cases, ages 0-4 years, from California's population-based @entity5 registry for 1988-1997. We matched 746 (88%) of these cases to a California live birth certificate. We randomly selected two control birth certificates for each case, matched on date of birth and gender. We used conditional logistic regression to obtain odds ratios (OR) and 95% CI. The birth characteristics examined included birthweight, gestational age, race, parental age, and parental education. RESULTS: Analysing all CNS @entity5 combined, we found that @entity1 of other racial/ ethnic groups had OR below one compared with non-Hispanic white @entity1 . When adjusted for gestational age, race/ethnicity, and mother's place of birth, the OR for high birthweight (>/=4000 g) was 1.05 (95% CI: 0.79-1.38) compared with @entity1 with birthweights of 2500-3999 g. For @entity816 (313 cases), the adjusted OR for high birthweight was 1.40 (95% CI: 0.90-2.18). When parental education was included in the model (available for only a subset of the birth years), the adjusted OR was 1.71 (95% CI: 1.01-2.90). High birthweight did not appear to be a risk factor for @entity5 ( @entity5 ). CONCLUSIONS: We found high birthweight associated with increased risk of @entity816 , but not @entity5 , in young @entity1 .

Birth characteristics and XXXX in young @entity1 .

@entity1 :: ('9606', 'Species') :: ['children'] @entity816 :: ('MESH:D001254', 'Disease') :: ['astrocytomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['PNET', 'cancer', 'tumours', 'primitive neuroectodermal tumours'] @entity1313 :: ('MESH:D001932', 'Disease') :: ['brain tumours', 'brain cancers']
@entity1313 :: (MESH:D001932,Disease) :: ['brain cancers']
