UNASSIGNED: Stereotactic radiation technique including single fraction radiosurgery and conventional fractionated stereotactic radiotherapy is widely reported as an effective treatment of @entity977 . Because of the restricted radiation tolerance dose of the optic pathway, single fraction radiosurgery has been accepted for small @entity5 located far away from the optic apparatus, while fractionated stereotactic radiotherapy may be suitable for larger @entity5 located close to the optic pathway. More recently, hypofractionated stereotactic radiotherapy has become an alternative treatment option that provides high rate of @entity5 control and visual preservation for the perioptic lesions within 2 to 3 mm of the optic pathway. The objective of the study was to analyze the clinical outcomes of perioptic @entity977 treated with hypofractionated stereotactic radiotherapy. From 2009 to 2012, 40 @entity1 with perioptic pituitary @entity652 were treated with CyberKnife robotic radiosurgery. The median @entity5 volume was 3.35 cm(3) (range, 0.82-25.86 cm(3)). The median prescribed dose was 25 Gy (range, 20-28 Gy) in 5 fractions (range, 3-5). After the median follow-up time of 38.5 months (range, 14-71 months), 1 (2.5%) @entity1 with @entity2013 had @entity5 enlargement, 31 (77.5%) were stable, and the remaining 8 (20%) @entity5 were smaller in size. No @entity1 's vision deteriorated after hypofractionated stereotactic radiotherapy. Hormone normalization was observed in 7 (54%) of 13 @entity1 . No newly developed @entity4614 was detected in our study. These data confirmed that hypofractionated stereotactic radiotherapy achieved high rates of @entity5 control and visual preservation. Because of the shorter duration of treatment, it may be preferable to use hypofractionated stereotactic radiotherapy over fractionated stereotactic radiotherapy for selected @entity977 immediately adjacent to the optic apparatus.

The Clinical Outcome of Hypofractionated Stereotactic Radiotherapy With CyberKnife Robotic Radiosurgery for Perioptic XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2013 :: ('MESH:D015175', 'Disease') :: ['prolactinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity4614 :: ('MESH:D007018', 'Disease') :: ['hypopituitarism'] @entity977 :: ('MESH:D010911', 'Disease') :: ['pituitary adenomas'] @entity652 :: ('MESH:D000236', 'Disease') :: ['adenoma']
@entity977 :: (MESH:D010911,Disease) :: ['Pituitary Adenoma']
