This study was a retrospective analysis of 75 @entity1 with perforated @entity1682 treated at the Baptist Medical Centre in Ogbomoso, Nigeria over a 4-year period. The mean age was 11.4 years. The usual symptoms were @entity221 and @entity490 , with a mean duration of 10.5 days. The diagnosis of perforation was usually based on the history and physical examination alone. The time interval from hospital presentation to operation was 11 hours, during which intravenous crystalloid and antibiotics were administered. Among the 75 @entity1 , 53 (71%) had a single perforation, and 22 had multiple perforations. D  bridement and two-layered closure was performed in 71 (95%) and resection with @entity254 in 4 (5%). Ileus resolution was usually not complete until the eighth postoperative day, and the mean time until the surviving @entity1 were afebrile was 10 days. Complications other than @entity204 occurred in 7 (9%) @entity1 , and there were 15 @entity204 (20% mortality). All @entity204 were attributed to overwhelming @entity295 , and all but one of the @entity204 occurred during the first 72 postoperative hours. The only factor statistically significant as a predictor of mortality was the duration of @entity490 . Improvement in perioperative management including intensive care nursing and more effective antibiotics, although expensive, could result in decreased mortality. A significant decrease in mortality can occur only when the prevention of @entity1682 becomes a higher priority than its treatment.

Typhoid intestinal perforations in Nigerian XXXX .

@entity1 :: ('9606', 'Species') :: ['children'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity254 :: ('MESH:C563598', 'Disease') :: ['anastomosis'] @entity490 :: ('MESH:D015746', 'Disease') :: ['abdominal pain'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death', 'deaths'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity1682 :: ('MESH:D014435', 'Disease') :: ['typhoid enteritis', 'typhoid fever']
@entity1 :: (9606,Species) :: ['children']
