OBJECTIVES: To evaluate the frequency of @entity1082 -related @entity957 in African Americans and whites and to examine @entity1 outcomes in these 2 groups. DESIGN: Retrospective study. SETTING: One tertiary care, university medical center. @entity1 : Information on @entity1 with stage III/IV @entity957 diagnosed between 1998 and 2007, and with primary surgical samples available for review, were selected from a radiotherapy database. One @entity1 was Native American and was excluded from analysis; data on 174 @entity1 were analyzed. RESULTS: One hundred forty-eight @entity1 (85.1%) were white and 26 (14.9%) were African American. @entity1082 in situ hybridization-positive and p16-positive @entity5 were much more common in whites (63.5% and 83.1% of @entity5 , respectively) than in African Americans (11.5% and 34.6% of @entity5 , respectively) (P < .001). African Americans were also more likely to have received definitive (nonsurgical) rather than postoperative radiation therapy (P = .001) and had a higher frequency of T3/T4-stage @entity5 (P = .03) compared with whites. Disease-free survival was significantly shorter for African Americans (P = .02). In multivariate analysis, viral status (P = .006), T stage (P = .02), and treatment type (P = .002), but not race (P = .98), were significant factors contributing to disease-free survival. CONCLUSIONS: In high-stage @entity957 , the proportion of @entity1082 -related @entity5 is much higher in whites than in African Americans. African Americans also appear to develop higher @entity5 and are more likely to receive definitive therapy. The shorter disease-free survival observed in African Americans may be due to viral status, treatment type, and higher T stage, but does not appear to be due to race.

@entity1082 -related XXXX of the oropharynx: a comparative study in whites and African Americans.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'PATIENTS'] @entity957 :: ('MESH:D002294', 'Disease') :: ['oropharyngeal squamous cell carcinoma'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumors', 'T-stage tumors'] @entity1082 :: ('10566', 'Species') :: ['human papillomavirus', 'Human papillomavirus']
@entity957 :: (MESH:D002294,Disease) :: ['squamous cell carcinoma']
