AIM: To examine whether high-flow nasal @entity26 (HFNO) availability influences the use of general anesthesia (GA) in @entity1 undergoing endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) and associated outcomes. METHODS: In this retrospective study, @entity1 were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras ( @entity7971 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo @entity7971 ( @entity7971 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included @entity26 saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively. RESULTS: During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in @entity7971 2 compared to @entity7971 1 with the same trend between @entity7971 2 and 3 (P = 0.012 and 0.045 respectively). The @entity26 saturation nadir during sedation was significantly higher in @entity7971 2 compared to @entity7971 3 (P < 0.001) but not between eras 1 and 2 (P = 0.028) or 1 and 3 (P = 0.069). The procedure time within each @entity7971 was significantly longer under GA compared to deep sedation (P <=  0.007) as was the anesthesia-only time (P <=  0.001). CONCLUSION: High-flow nasal @entity26 availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation.

High-flow nasal XXXX availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity26 :: ('MESH:D010100', 'Chemical') :: ['oxygen'] @entity7971 :: ('26284', 'Gene') :: ['era']
@entity26 :: (MESH:D010100,Chemical) :: ['oxygen']
