BACKGROUND AND OBJECTIVES: Lymph node involvement adversely affects the survival of @entity1 with @entity418 . We retrospectively investigated whether the number of involved lymph nodes and the degree of lymph node dissection affect survival. @entity1 AND METHODS: Eighty-eight @entity1 underwent surgical resection and reconstruction for T -T3 @entity1721 . @entity1 were classified into three groups: group 1, 32 @entity1 without lymph node involvement; group 2, 26 @entity1 with 1 to 3 positive nodes; and group 3, 30 @entity1 with > or = 4 involved lymph nodes. RESULTS: The 3-year and 5-year survival rates were 34.8% and 30.0% in group 1, 30.0% and 22.7% in group 2, and 14.8% and 0% in group 3, respectively. The @entity1349 ( @entity1349 ) X +/- SD of the @entity1 in group 3 (453.06+/-74.5 days) was significantly shorter than in group 1 (450.1+/-450.5, P = 0.0005) and group 2 (937.3+/-1317.9, P = 0.0295). For @entity1 in groups 1 and 2, the @entity1349 for three-field lymph node dissection (1136.9+/-1476.4 days) was longer than for two-field lymph node dissection (1007.4+/-1476.4 days, P = 0.0355). However, in group 3, there was no survival advantage to three-field lymph node dissection. CONCLUSION: We conclude that the survival in @entity1 with @entity418 involving four or more nodes, is poorer than in @entity1 with lesser involvement. Three-field lymph node dissection does contribute to prolonged survival in @entity1 with node-negative disease or fewer than four positive nodes.

The number of lymph node metastases influences survival in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients', 'PATIENTS'] @entity1721 :: ('MESH:C562729', 'Disease') :: ['thoracic esophageal squamous cell carcinoma'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal cancer', 'thoracic esophageal cancer'] @entity1349 :: ('MESH:D011475', 'Disease') :: ['mean survival time', 'MST']
@entity418 :: (MESH:D004938,Disease) :: ['esophageal cancer']
