OBJECTIVE: To assess the time course of arterial adaptations during 6 weeks of functional electric stimulation (FES) training and 6 weeks of detraining in subjects with @entity1566 ( @entity1566 ). DESIGN: Intervention study (before-after trial). SETTING: University medical center. @entity1 : Volunteer sample of 9 subjects with @entity1566 . INTERVENTIONS: Six weeks of twice weekly FES cycling and 6 weeks of detraining. MAIN OUTCOME MEASURES: Vascular characteristics were measured by plethysmography (baseline and peak blood flow of the thigh) and echo Doppler (diameter of the femoral artery and @entity384 [ @entity384 ]). RESULTS: After 2 weeks of FES training, arterial characteristics changed significantly; there was an increase in baseline and peak blood flow, an increase in femoral artery diameter, and a decrease in @entity384 of the femoral artery. Detraining reversed baseline and peak thigh blood flow, vascular resistance, and femoral diameter toward pretraining values within 1 week. However, detraining did not restore the @entity384 of the femoral artery, even after 6 weeks. CONCLUSIONS: Two weeks of hybrid FES training (4 exercise bouts) is sufficient to improve peak leg blood flow and arterial diameter, and to normalize @entity384 . In addition, detraining results in rapidly reversed vascular characteristics within 1 week.

Rapid vascular adaptations to training and detraining in XXXX with @entity1566 .

@entity1566 :: ('MESH:D013119', 'Disease') :: ['spinal cord injury', 'SCI'] @entity1 :: ('9606', 'Species') :: ['PARTICIPANTS'] @entity384 :: ('MESH:D002311', 'Disease') :: ['flow-mediated dilation', 'FMD']
@entity1 :: (9606,Species) :: ['persons']
