BACKGROUND: Resuscitation guidelines often recommend ongoing cardiopulmonary resuscitation (CPR) efforts to hospital for @entity1167 ( @entity1167 ) witnessed by emergency medical service (EMS) personnel. In this study, we examine the relationship between EMS CPR duration and survival to hospital discharge in EMS witnessed @entity1167 @entity1 . METHODS: Between January 2003 and December 2011, 1035 adult EMS witnessed arrests of presumed cardiac aetiology were included from the Victorian Ambulance Cardiac Arrest Registry. CPR duration was defined as the total sum of prehospital CPR time in minutes. Adjusted logistic regression analyses were used to assess the impact of EMS CPR duration on survival to hospital discharge. RESULTS: 382 (37.3%) @entity1 were discharged alive. The median CPR duration was 12min (95% CI: 11-13) overall, but was higher in non-survivors compared to survivors (24min vs. 2min, p<0.001). The 99th percentile CPR duration in @entity1 surviving to hospital discharge differed by the initial rhythm of arrest: 32min (95% CI: 27-44) overall, 32min (95% CI: 23-44) for @entity2224 and pulseless @entity1165 (VF/VT), 34min (95% CI: 30-34) for pulseless electrical activity ( @entity3587 ), and 28min (95% CI: 21-28) for @entity1167 . There were no survivors after 44min for all rhythms. After adjusting for prehospital confounders, every minute increase in CPR duration was associated with a 13% reduction in the odds of survival to hospital discharge (OR 0.87, 95% CI: 0.84-0.89, p<0.001). The multivariable model predicted no chance of survival at or after a CPR duration of 48min for VF/VT @entity1 , 47min for @entity3587 @entity1 and 45min for @entity1167 @entity1 . CONCLUSION: Resuscitation efforts exceeding 32min yielded less than 1% of survivors from EMS witnessed @entity1167 . On the basis of this data, EMS witnessed @entity1167 @entity1 may benefit from ongoing CPR efforts up to 48min in duration.

Impact of cardiopulmonary resuscitation duration on survival from paramedic witnessed XXXX : An observational study.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachycardia'] @entity2224 :: ('MESH:D014693', 'Disease') :: ['ventricular fibrillation'] @entity1167 :: ('MESH:D006323', 'Disease') :: ['out-of-hospital cardiac arrests', 'asystole', 'OHCA'] @entity3587 :: ('3888', 'Species') :: ['PEA']
@entity1167 :: (MESH:D006323,Disease) :: ['out-of-hospital cardiac arrests']
