Fruit morphogenesis is a process unique to flowering plants, and yet little is known about its developmental control. Following fertilization, fruits typically undergo a dramatic enlargement that is accompanied by differentiation of numerous distinct cell types. We have identified a mutation in @entity958 called fruitfull ( @entity29399 -1), which abolishes elongation of the silique after fertilization. The @entity29399 -1 mutation is caused by the insertion of a DsE transposable enhancer trap element into the 5' untranslated leader of the @entity29399 MADS-box gene. beta-glucuronidase (GUS) reporter gene expression in the enhancer trap line is observed specifically in all cell layers of the valve tissue, but not in the replum, the septum or the seeds, and faithfully mimics RNA in situ hybridization data reported previously. The lack of coordinated growth of the fruit tissues leads to crowded seeds, a failure of dehiscence and, frequently, the premature @entity397 . The primary defect of @entity29399 -1 fruits is within the valves, whose cells fail to elongate and differentiate. Stomata, which are frequent along the epidermis of wild-type valves, are completely eliminated in the @entity29399 mutant valves. In addition to the effect on fruit development, @entity29399 cauline leaves are broader than those of wild type and show a reduction in the number of internal cell layers. These data suggest that @entity29399 / @entity29399 regulates the transcription of genes required for cellular differentiation during fruit and leaf development.

The FRUITFULL MADS-box gene mediates cell differentiation during XXXX fruit development.

@entity958 :: ('3702', 'Species') :: ['Arabidopsis'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture of the carpel valves'] @entity29399 :: ('836212(Tax:3702)', 'Gene') :: ['FUL', 'ful', 'AGL8']
@entity958 :: (3702,Species) :: ['Arabidopsis']
