OBJECTIVE: To study the efficacy of intrathecal @entity1068 block to relieve intractable @entity508 in @entity791 -related @entity7578 ( @entity7578 ) when long-term intrathecal @entity1772 infusion cannot be used. METHODS: A 33-year-old @entity1 with @entity791 -related @entity7578 developed very severe @entity3500 ( @entity2003 score, 4) and painful @entity2473 . The @entity1 was unable to sit in his wheelchair and remained bed bound. Combined oral @entity1772 and @entity21819 at therapeutical doses were used without any effect on the @entity508 . The @entity1 refused the placement of an intrathecal catheter for long-term @entity1772 infusion. A single intrathecal @entity1068 (6 ml) injection in the L2-L3 intervertebral space with the @entity1 placed in a lateral Trendelenburg (40 C) position was performed. RESULTS: The procedure was very effective in improving the stiffness ( @entity2003 score. 2, after the technique) and the @entity2473 disappeared. No side effects during or after the injection were observed. CONCLUSION: Intrathecal @entity1068 block is a last but very useful choice for treatment of intractable @entity508 in @entity7578 and other @entity16 in @entity791 @entity1 when other oral treatments have failed and intrathecal @entity1772 infusion is not suitable.

Successful intrathecal @entity1068 block for intractable @entity508 of XXXX -related @entity7578 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient', 'man'] @entity791 :: ('MESH:D000163', 'Disease') :: ['AIDS'] @entity2003 :: ('MESH:D009127', 'Disease') :: ['Ashworth rigidity'] @entity21819 :: ('MESH:C023754', 'Chemical') :: ['tizanidine'] @entity3500 :: ('MESH:D020336', 'Disease') :: ['spastic paraparesis'] @entity508 :: ('MESH:D009128', 'Disease') :: ['spasticity'] @entity16 :: ('MESH:D009422', 'Disease') :: ['neurologic disorders'] @entity2473 :: ('MESH:D013035', 'Disease') :: ['muscle spasms'] @entity1772 :: ('MESH:D001418', 'Chemical') :: ['baclofen'] @entity1068 :: ('MESH:D000431', 'Chemical') :: ['ethanol'] @entity7578 :: ('MESH:D007968', 'Disease') :: ['progressive multifocal leukoencephalopathy', 'PML']
@entity791 :: (MESH:D000163,Disease) :: ['AIDS']
