PURPOSE: To estimate the prevalence of @entity15439 in Heidelberg and Mannheim and to map its geographical distribution in Germany. METHODS: @entity15439 @entity1 were ascertained through the databases of the Low Vision Department at the University of Heidelberg, and of the @entity1 support group Pro Retina. Ophthalmic and audiologic examinations and medical records were used to classify @entity1 into one of the subtypes. RESULTS: The database of the University of Heidelberg contains 247 @entity15439 @entity1 , 63 with @entity15439 ( @entity37305 ) and 184 with @entity15439 ( @entity24129 ). The @entity37305 : @entity24129 ratio in the Heidelberg database was 1:3. The Pro Retina database includes 248 @entity15439 @entity1 , 21 with @entity37305 and 227 with @entity24129 . The total number of @entity15439 @entity1 was 424, with 75 @entity37305 and 349 @entity24129 @entity1 ; 71 @entity1 were in both databases. The prevalence of @entity15439 in Heidelberg and suburbs was calculated to be 6.2 per 100,000 inhabitants. There seems to be a homogeneous distribution in Germany for both subtypes. CONCLUSION: Knowledge of the high prevalence of @entity15439 , with up to 5,000 @entity1 in Germany, should lead to increased awareness and timely diagnosis by ophthalmologists and otologists. It should also ensure that these @entity1 receive good support through hearing and vision aids.

Prevalence and geographical distribution of XXXX in Germany.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity24129 :: ('7399', 'Gene') :: ['USH2'] @entity37305 :: ('MESH:C536488', 'Disease') :: ['USH1'] @entity15439 :: ('MESH:D052245', 'Disease') :: ['Usher syndrome type 1', 'Usher syndrome type 2', 'Usher syndrome']
@entity15439 :: (MESH:D052245,Disease) :: ['Usher syndrome']
