PURPOSE: To determine the efficacy and safety of oral @entity1169 as a first-line treatment for superficially located @entity7492 ( @entity7492 ) and propose an assessment tool to measure treatment response. METHODS: @entity1 with superficial @entity7492 under 1 year of age were prospectively recruited between May 2012 and December 2013 at the Department of Pediatrics of Chungbuk National University Hospital. @entity1169 was administered to 12 @entity1 (median age, 3.8 months) while monitoring cardiovascular and adverse metabolic effects. If a @entity1 showed no adverse events, the dosage was gradually increased up to 3 mg/kg/day and maintained for 1 year. We used our own scoring system to assess treatment response using parameters like change in color, and longest diameter, and thickness of the @entity7492 . RESULTS: Eleven out of 12 @entity1 completed the protocol with consistent improvement of @entity2695 during therapy. @entity1 on @entity1169 showed a more than 50% involution in the first 3 months, with additional steady involution until 1 year. @entity1 with the highest scores at 1 month maintained their score and showed better responses until treatment termination. The @entity1 with the lowest score at 1 month did not show any further regression and stopped @entity1169 treatment 4 months after initiation. In two @entity1 with recurrences after successful therapeutic regression, @entity1169 was effective after being reintroduced. @entity1169 treatment was not interrupted in any @entity1 due to adverse events. CONCLUSION: Oral @entity1169 at 3 mg/kg/day showed a consistent, rapid, and therapeutic effect on superficial IHs without significant adverse events.

A prospective study to assess the efficacy and safety of oral XXXX as first-line treatment for infantile superficial @entity2695 .

@entity1169 :: ('MESH:D011433', 'Chemical') :: ['propranolol', 'Propranolol'] @entity7492 :: ('MESH:C535860', 'Disease') :: ['IH', 'infantile hemangioma'] @entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'patient', 'infants'] @entity2695 :: ('MESH:D006391', 'Disease') :: ['hemangiomas']
@entity1169 :: (MESH:D011433,Chemical) :: ['propranolol']
