We prospectively studied the type, frequency and outcome of @entity281 in 513 @entity1 with 762 consecutive episodes of @entity1398 ( @entity1398 ) over a five-year period between 1995 and 1999 in a single paediatric oncology unit. The findings were then compared with a similar study carried out in our unit between 1990 and 1994. The types of bacterial isolates and sensitivity patterns were also studied to identify trends and to gauge the suitability of antibiotics chosen for empirical therapy. @entity582 was documented in 35.4% of @entity1398 episodes, although 70% of @entity1 did not have an obvious site of @entity295 . The majority of isolates (61.9%) were gram-negative bacteria, a consistent finding throughout the study period. Resistance to @entity5505 , @entity4509 and imipenem among gram-negative bacteria was 26.3%, 21.2% and 0.7%, respectively. Methicillin resistance among gram-positive bacteria was 26.3%, while no @entity2176 -resistant bacteria were encountered. There were 36 @entity295 -related @entity204 . Factors associated with a fatal outome were prolonged capillary refill time, @entity551 , @entity221 above 39 degrees C and @entity55 . Rapid neutrophil recovery was associated with a good prognosis. A change to our current choice of empirical antibiotics for @entity1398 , comprising @entity5505 / @entity2756 and @entity4509 appears necessary because of the relatively high resistance rates found.

Surveillance study of bacteraemic episodes in febrile neutropenic XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity2756 :: ('MESH:D002443', 'Chemical') :: ['ceftriaxone'] @entity295 :: ('MESH:D018805', 'Disease') :: ['sepsis'] @entity2176 :: ('MESH:D014640', 'Chemical') :: ['vancomycin'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever'] @entity4509 :: ('MESH:D000583', 'Chemical') :: ['amikacin'] @entity551 :: ('MESH:D007022', 'Disease') :: ['hypotension'] @entity281 :: ('MESH:D007239', 'Disease') :: ['infections'] @entity1398 :: ('MESH:D009503', 'Disease') :: ['FN', 'febrile neutropenia'] @entity582 :: ('MESH:C531821', 'Disease') :: ['Bacteraemia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['deaths'] @entity5505 :: ('MESH:D002442', 'Chemical') :: ['ceftazidime']
@entity1 :: (9606,Species) :: ['children']
