There has been a growing awareness of the association between @entity3557 and @entity1412 ( @entity1412 ). The cases of four young @entity1 with @entity3557 occurring with @entity1412 are presented. Three @entity1 underwent surgery to provide specimens for detailed histological examination. The surgical specimens showed well-encapsulated multicentric @entity5 exhibiting a predominantly papillary architectural growth pattern. In some areas, follicular architecture and cribriform patterns were noted. Atypical areas of spindle cells in a trabecular or solid configuration, which are not normally seen in classical @entity3557 , were evident. Malignant cells exhibited a graduation of cuboidal to tall cells with abundant amphophilic cytoplasm. The nuclei did not exhibit the typical nuclear clearing as seen in @entity3557 , but nuclear grooving and inclusions were noted. Psammoma bodies were not seen in any of the specimens. In a limited review of these @entity1 , features such as young age at presentation, multicentricity and unusual histology suggest that @entity259 associated with @entity1412 may represent a distinct form of @entity259 .

@entity259 in @entity1 with XXXX .

@entity3557 :: ('MESH:C536915', 'Disease') :: ['papillary thyroid carcinoma'] @entity1 :: ('9606', 'Species') :: ['patients'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumours'] @entity1412 :: ('MESH:D011125', 'Disease') :: ['familial adenomatous polyposis', 'FAP'] @entity259 :: ('MESH:D013964', 'Disease') :: ['thyroid cancer', 'thyroid carcinoma']
@entity1412 :: (MESH:D011125,Disease) :: ['familial adenomatous polyposis']
