BACKGROUND AND STUDY AIMS: Angiographic and surgical therapy are standards of care for persistent diverticular @entity548 . Colonoscopic intervention using epinephrine injection, multipolar electrocautery, and placement of an Endoclip has not gained widespread acceptance due to concerns about complications,and the widespread management of severe lower @entity360 by surgeons and interventional radiologists. The utility of colonoscopic band ligation for control of diverticular @entity548 was evaluated both in vivo and ex vivo. @entity1 AND METHODS: Endoscopic band ligation of @entity7261 was performed on surgical resection specimens and in @entity1 with actively @entity548 @entity17825 . RESULTS: In the in-vivo study, active diverticular @entity548 was completely controlled in four @entity1 by endoscopic band ligation. In two cases, a visible vessel was seen on the everted and banded diverticulum. Procedure time ranged from 45 to 140 min. The total lengths of hospital stays for the four @entity1 were 2, 6, 14, and 35 days. The long hospital stays (> 7 days)were associated with non-gastrointestinal co-morbidity. There were no acute complications of band ligation. No rebleeding or need for surgery occurred during a follow-up period of 12 months in any of the @entity1 . In the ex-vivo study, 11 @entity7261 were successfully everted and banded in five of nine surgical specimens (one right colon and four left colons). Mucosa was identified in all of the "banded" segments. Ten of 11 ligated @entity7261 revealed evidence of blood vessels or submucosal tissue. The presence of subserosal fat was suggested in three of the 11 "banded" segments, and none of the ex-vivo ligated @entity7261 contained muscularis propria or serosal involvement. There was no evidence of perforation. CONCLUSIONS: Both in-vivo and ex-vivo data suggest that endoscopic band ligation may be a safe and effective therapy for actively @entity548 @entity17825 .

Treatment of XXXX @entity17825 by endoscopic band ligation: an in-vivo and ex-vivo pilot study.

@entity1 :: ('9606', 'Species') :: ['patients', 'PATIENTS'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding'] @entity17825 :: ('MESH:D004241', 'Disease') :: ['colonic diverticula'] @entity7261 :: ('MESH:D004240', 'Disease') :: ['diverticula'] @entity360 :: ('MESH:D006471', 'Disease') :: ['gastrointestinal bleeding']
@entity548 :: (MESH:D006470,Disease) :: ['bleeding']
