BACKGROUND: @entity11037 ( @entity11037 ) is an important postoperative problem with an incidence of 20% to 35% especially prevalent after the removal of mandibular molars. Fibrinolysis with subsequent loss of @entity4461 is believed to be the general cause of @entity11037 . OBJECTIVES: This study aims to evaluate the efficacy of @entity927 , an antifibrinolytic agent in comparison with a placebo with respect to the reduction of incidence of @entity11037 after the extraction of mandibular molars by using following parameters: @entity158 , disintegration of Clot, @entity7868 . MATERIALS AND METHODS: A double blind study consisted of 60 @entity1 , who underwent routine dental extractions of mandibular molar teeth. Group A (30 @entity1 ) requiring routine dental extractions of mandibular teeth was randomly selected and was administered a dose of @entity927 orally (Pause 500mg) one hour prior to extraction of teeth. Gel foam soaked in @entity927 (160mg) was placed into the extraction socket postoperatively. A figure of eight silk suture was placed over the socket to secure the gelfoam. Group B (30 @entity1 ); a placebo ( @entity24149 ) was given orally one hour prior to the extraction and gel foam soaked in saline was placed into the extraction socket postoperatively. A figure of eight silk suture was placed over the socket. @entity158 was rated individually by each @entity1 at 3(rd), 7(th), 14(th) day after extraction and the results was statistically analysed. RESULTS: This study supports that the use of @entity927 both locally and systemically following the removal of the teeth reduces the incidence of @entity11037 associated with the extraction of mandibular molars. CONCLUSION: @entity927 has several advantages also when used for simple dental extractions, namely: low cost and ready availability and therefore we recommend this treatment modality.

The Efficacy of XXXX in the Reduction of Incidence of Dry Socket: An Institutional Double Blind Study.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity7868 :: ('MESH:D006209', 'Disease') :: ['halitosis'] @entity11037 :: ('MESH:D004368', 'Disease') :: ['Alveolar osteitis', 'AO'] @entity4461 :: ('MESH:D020141', 'Disease') :: ['blood clotting'] @entity158 :: ('MESH:D010146', 'Disease') :: ['Pain'] @entity927 :: ('MESH:D014148', 'Chemical') :: ['tranexamic acid', 'Tranexamic acid'] @entity24149 :: ('MESH:C029036', 'Chemical') :: ['crocin']
@entity927 :: (MESH:D014148,Chemical) :: ['Tranexamic Acid']
