OBJECTIVE: To clarify the functional subdivisions of the @entity1 lateral premotor cortex (PM) in the visuomotor control. METHODS: Event-related potentials (ERPs) were epicortically recorded from PM in 5 @entity302 @entity1 . S1-Go/ @entity14841 choice delayed @entity137 ( @entity137 ), S1-warned S2-Go simple @entity137 and control fixation paradigms were compared using paired visual stimuli (S1, S2). RESULTS: Signal-related activity peaked at 176-194 ms after S1 in the ventrorostral PM (PMvr) in all 3 paradigms, indicating its role in signal perception. Early set-related activity was recorded with its peak <810 ms after S1 in the dorsorostral PM (PMdr) and was larger in the choice than in the simple @entity137 paradigm, suggesting its role in signal selection. Its cognitive component was recorded as surface-positive transients at PMdr, while its motoric aspect, seen as negative transients, extended to the caudal PM. Late sustained set-related activity was observed in preparation for hand movement in the caudal PM at the hand and face positive motor areas. After presentation of S2, movement-related activity was observed at the hand sensorimotor area for motor execution, following the signal-related activity at PMvr. CONCLUSIONS: The present ERP study suggests the temporally sequential representation of predominantly 'cognitive' function in the rostral PM and 'motor' function in the caudal PM. SIGNIFICANCE: The rostrocaudal cognitive-motor gradient was demonstrated in the lateral premotor cortex in @entity1 by means of an epicortical ERP approach.

Motor-related functional subdivisions of XXXX lateral premotor cortex: epicortical recording in conditional visuomotor task.

@entity1 :: ('9606', 'Species') :: ['humans', 'human', 'patients'] @entity14841 :: ('57142', 'Gene') :: ['NoGo'] @entity137 :: ('MESH:D064420', 'Disease') :: ['reaction time', 'RT'] @entity302 :: ('MESH:D004827', 'Disease') :: ['epilepsy']
@entity1 :: (9606,Species) :: ['human']
