UNASSIGNED: This study was conducted to investigate the effect of combining extremely low frequency-pulsed electromagnetic field ( @entity51507 -PEMF) and low-level laser therapy (LLLT) on alkali-burned @entity95 corneas. Fifty alkali-burned corneas of 50 @entity95 were categorized into five groups: @entity51507 -PEMF therapy with 2  mT intensity ( @entity51508 ) for 2  h daily; LLLT for 30  min twice daily; combined @entity51507 -PEMF and LLLT ( @entity51507  +  LLLT); medical therapy (MT); and control (i.e., no treatment). Clinical examination and digital photography of the corneas were performed on days 0, 2, 7, and 14. After euthanizing the @entity95 , the affected eyes were evaluated by histopathology. The clinical and histopathologic results were compared between the groups. On days 7 and 14, no significant difference in the @entity2687 area was evident between the @entity51507 , LLLT, @entity51507  +  LLLT, and MT groups. Excluding the controls, none of the study groups demonstrated a significant @entity7499 in both routine histopathology and immunohistochemistry for CD31. Keratocyte loss was significantly higher in the MT group than in the @entity51507 , LLLT, and @entity51507  +  LLLT groups. Moderate to severe @entity32 in the LLLT group was comparable with that in the MT group and was significantly lower than that in the other groups. In conclusion, combining LLLT and @entity51507 was not superior to @entity51507 alone or LLLT alone in healing @entity2687 . However, given the lower intensity of @entity32 and the lower rate of keratocytes loss with LLLT, this treatment may be superior to other proposed treatment modalities for healing alkali-burned corneas.

Short-term effects of extremely low-frequency pulsed electromagnetic field and pulsed low-level laser therapy on XXXX model of @entity2687 .

@entity32 :: ('MESH:D007249', 'Disease') :: ['stromal inflammation', 'corneal inflammation'] @entity7499 :: ('MESH:D016510', 'Disease') :: ['corneal neovascularization'] @entity51508 :: ('100344338(Tax:9986)', 'Gene') :: ['ELF 2'] @entity95 :: ('9986', 'Species') :: ['rabbits', 'rabbit'] @entity51507 :: ('100008618(Tax:9986)', 'Gene') :: ['ELF'] @entity2687 :: ('MESH:D003316', 'Disease') :: ['corneal defect', 'corneal alkali burns']
@entity95 :: (9986,Species) :: ['rabbit']
