UNASSIGNED: @entity6 has been reported to increase the risk of @entity150 , but the studies' results are still inconclusive. Age, sex, and geographical area-specific incidence and relative risks of above @entity5 are also scarce in the literature. We prospectively investigated the age, sex, geographical area-specific incidence and relative risks of kidney and @entity150 in @entity6 population of Taiwan. @entity6 @entity1 (n=615,532) and age- and sex-matched controls (n=614,871) were linked to inpatient claims (2000-2008) to identify the admissions for @entity703 (International Classification of Diagnosis, 9th version, Clinical Modification: 189) and bladder (International Classification of Diagnosis, 9th version, Clinical Modification: 188). The @entity1 -year approach with Poisson assumption was used to evaluate the incidence density. We also estimated the age, sex, and geographical area-specific relative risks of @entity5 in relation to @entity6 with Cox proportional hazard regression model.The overall incidence density of @entity703 for @entity6 @entity1 and @entity1 were 3.87 and 4.28 per 10,000 @entity1 -years, respectively; the corresponding figures for @entity150 were 5.73 and 3.25 per 10,000 @entity1 -years. Compared with the controls, @entity6 @entity1 were at significantly increased hazards of kidney (covariate adjusted hazard ratio [aHR]: 1.31, 95% confidence interval [CI] 1.18-1.46) and bladder aHR: 1.13, 95% CI 1.04-1.23). @entity6 @entity1 , on the contrary, only experienced significantly elevated @entity703 (aHR: 1.14, 95% CI 1.04-1.26). @entity6 @entity1 aged >65 years showed the most significantly increased hazard of developing @entity703 (aHR: 1.40) and bladder (aHR: 1.13). The most significantly increased @entity703 was noted for @entity1 @entity6 @entity1 aged >65 years. There was also a significant interactive effect of geographic area with @entity6 on the incidence of kidney and @entity150 in both sexes. @entity6 @entity1 >45 years and @entity6 @entity1 >65 years were found to have significantly increased hazard of @entity703 , but only @entity6 @entity1 >65 years were at significantly increased hazard of @entity150 . The significant geographic variations in incidence and relative hazard of kidney and @entity150 warrant further investigations of the underlying reasons.

Risk of Malignant Neoplasms of Kidney and Bladder in a Cohort Study of the XXXX Population in Taiwan With Age, Sex, and Geographic Area Stratifications.

@entity1 :: ('9606', 'Species') :: ['women', 'patients', 'patient', 'person', 'men'] @entity6 :: ('MESH:D003920', 'Disease') :: ['Diabetes', 'Diabetic', 'diabetic', 'diabetes'] @entity5 :: ('MESH:D009369', 'Disease') :: ['above malignancy', 'neoplasms'] @entity150 :: ('MESH:D001749', 'Disease') :: ['malignant neoplasms of kidney and bladder', 'bladder neoplasms', 'malignant neoplasm of bladder', 'bladder neoplasm'] @entity703 :: ('MESH:D007680', 'Disease') :: ['malignant neoplasm of kidney', 'neoplasm of kidney', 'hazard of kidney neoplasm']
@entity6 :: (MESH:D003920,Disease) :: ['Diabetic']
