UNASSIGNED: @entity438 represent 5% of @entity438 , and become symptomatic between 40 and 70years with a female predominance. In the paediatric population, the @entity439 rate is higher than in the adult population. Classified as saccular, fusiform and @entity9155 , the natural history of @entity438 is characterized by @entity715 , growth and @entity397 . The pathogenesis of these @entity439 is influenced by a number of risk factors, including genetic variables. Genome-wide association studies have identified some chromosomes highlighting candidate genes. Although these @entity439 can occur at the same locations as their smaller counterparts, a predilection for the cavernous location has been observed. @entity439 present with symptoms caused by a mass effect depending on their location or by @entity397 ; @entity63 manifestations rarely reveal the @entity439 . If the initial clinical descriptions have been back up by imagery, the clinical context with a pertinent analysis of the risk factors remain the cornerstone for the management decisions of these lesions. Five year cumulative @entity397 rates for @entity1 with @entity439 were 40% for those located on the anterior part of circle of Willis and 50% for those on the posterior part. The poor outcome of untreated @entity1 justifies the therapeutic risks.

Epidemiology, genetic, natural history and clinical presentation of XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemic'] @entity397 :: ('MESH:D012421', 'Disease') :: ['rupture'] @entity439 :: ('MESH:D000783', 'Disease') :: ['giant aneurysms', 'giant aneurysm', 'Giant aneurysms', 'aneurysm'] @entity9155 :: ('CHEBI:46670', 'Chemical') :: ['serpentine'] @entity715 :: ('MESH:D013927', 'Disease') :: ['thrombosis'] @entity438 :: ('MESH:D002532', 'Disease') :: ['Giant cerebral aneurysms', 'giant cerebral aneurysms', 'intracranial aneurysms']
@entity438 :: (MESH:D002532,Disease) :: ['giant cerebral aneurysms']
