1. This study examined the effect of an acute injection of contrast medium on generation of @entity943 in diseased hearts in @entity1 .2. Subjects were 100 @entity1 in sinus rhythm undergoing cardiac catheterization in whom good quality echocardiograms could be obtained. The subjects comprised 78 males and 22 females aged 37-83 years.3. @entity943 induced by left ventricular angiography ranged from nil to brief bursts of @entity1165 . There was a strongly positive relationship between left ventricular internal dimension in diastole (LVIDd) and induced @entity943 . Out of 26 @entity1 , 25 developed @entity943 when LVIDd>=5 cm (96%), but only 24 out of 74 @entity1 developed @entity943 when LVIDd<5 cm (32%) (P<0.001). In non-dilated hearts where K+<4.0 mmol/l, @entity943 developed in 100% (10 out of 10) of those with @entity4346 ( @entity4346 ), but in only 40% (8 out of 20) without @entity4346 (P<0. 005). Where K+>=4.0 mmol/l, no @entity943 occurred in @entity1 with @entity4346 but was present in 52% (31 out of 60) of @entity1 without @entity4346 (P<0.005). There were no relationships with age, end-diastolic pressure, blood pressure, @entity299 or sex of @entity1 . 4. These data support the view that acute injection of contrast medium in @entity1 induces @entity943 dependent upon the underlying state of the heart, with potentially complex interplay between left ventricular dimension, @entity1184 and @entity972 status, supporting similar observations in experimental animals.

Arrhythmogenic effect of ventriculography in @entity1 with left ventricular dilation and/or XXXX .

@entity1 :: ('9606', 'Species') :: ['humans', 'patients', 'patient', 'man'] @entity972 :: ('MESH:D011188', 'Chemical') :: ['potassium'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachycardia'] @entity1184 :: ('MESH:D006984', 'Disease') :: ['hypertrophy'] @entity4346 :: ('MESH:D017379', 'Disease') :: ['left ventricular hypertrophy', 'LVH'] @entity299 :: ('MESH:D006331', 'Disease') :: ['ischaemic heart disease'] @entity943 :: ('MESH:D001145', 'Disease') :: ['Arrhythmia', 'arrhythmias', 'arrhythmia']
@entity1184 :: (MESH:D006984,Disease) :: ['hypertrophy']
