BACKGROUND: Phase-contrast magnetic resonance imaging (PC-MRI) enables quantification of cerebrospinal fluid (CSF) flow and total cerebral blood (tCBF) flow and may be of value for the etiological diagnosis of @entity179 . This investigation aimed to study CSF flow and intracerebral vascular flow in @entity1 with @entity195 ( @entity195 ) and @entity1 with @entity73 ( @entity73 ) and to compare the results with @entity1 with @entity5083 ( @entity5083 ) and with healthy elderly volunteers ( @entity4973 ). METHODS: Ten @entity73 and 9 mild @entity195 @entity1 were identified in a comprehensive neurological and neuropsychological assessment. They underwent brain MRI; PC-MRI pulse sequence was performed with the following parameters: two views per segment; @entity1182 angle: 25   for vascular flow and 20   for CSF flow; field-of-view (FOV): 14   14 mm  ; matrix: 256   128; slice thickness: 5 mm; with one excitation for exams on the 3 T machine, and 2 excitations for the 1.5 T machine exams. Velocity (encoding) sensitization was set to 80 cm/s for the vessels at the cervical level, 10 or 20 cm/s for the aqueduct and 5 cm/s for the cervical subarachnoid space (SAS). Dynamic flow images were analyzed with in-house processing software. The @entity1 ' results were compared with those obtained for HEVs (n = 12), and for @entity5083 @entity1 (n = 13), using multivariate analysis. RESULTS: Arterial tCBF and the calculated pulsatility index were significantly greater in @entity73 @entity1 than in HEVs. In contrast, vascular parameters were lower in @entity5083 @entity1 . Cervical CSF flow analysis yielded similar values for all four populations. Aqueductal CSF @entity64 volumes (in  l per cardiac cycle) were similar in HEVs (34    17) and @entity195 @entity1 (39    18). In contrast, the aqueductal CSF was hyperdynamic in @entity73 @entity1 (73    33) and even more so in @entity5083 @entity1 (167    89). CONCLUSION: Our preliminary data show that @entity73 @entity1 present with high systolic arterial peak flows, which are associated with higher mean total cerebral arterial flows. @entity8468 are within normal range in @entity195 and higher than normal in @entity5083 . This study provides an original dynamic vision of cerebral @entity179 , consistent with the vascular theory for @entity195 , and supporting primary flow disturbances different from those observed in @entity5083 .

Cerebrospinal fluid and blood flow in mild @entity73 and @entity195 : a differential diagnosis from XXXX .

@entity1 :: ('9606', 'Species') :: ['patients'] @entity1182 :: ('8837', 'Gene') :: ['flip'] @entity64 :: ('MESH:D020521', 'Disease') :: ['stroke'] @entity73 :: ('MESH:D003072', 'Disease') :: ['a-MCI', 'amnesic mild cognitive impairment'] @entity4973 :: ('42005', 'Species') :: ['HEV'] @entity8468 :: ('OMIM:600791', 'Disease') :: ['Aqueductal CSF oscillations'] @entity179 :: ('MESH:D019636', 'Disease') :: ['neurodegenerative diseases'] @entity195 :: ('MESH:D000544', 'Disease') :: ['AD', "Alzheimer's disease"] @entity5083 :: ('MESH:D006850', 'Disease') :: ['idiopathic normal pressure hydrocephalus', 'NPH']
@entity5083 :: (MESH:D006850,Disease) :: ['idiopathic normal pressure hydrocephalus']
