OBJECTIVE: To analyze the curative effect of aggressive B cell @entity1893 and relevant influencing factors of its prognosis. METHODS: The curative effects of aggressive @entity1893 which were diagnosed as diffuse small cleaved (E), diffuse mixed (F), diffuse large cell (G) or diffuse @entity706 (H) pathologically and certified as @entity1892 immunohistologically and treated with @entity3726 or other ADM-containing regimens for at least 4 cycles from 1993 to 1997 were analyzed. An analysis of the correlation of prognosis with different factors was made. RESULTS: The curative effects of 191 out of the 230 cases were evaluated. 131 (68.9%) @entity1 achieved CR, and 47 (24.6%) achieved PR. The 6-year @entity1349 ( @entity1349 ) rates and progress free survival (PFS) rates were 51.4% and 43.3% respectively. According to IPI risk stratification, the 6-year @entity1349 rates were 66.6%, 42.2%, 23.6%, and 10.0% in the low-risk, low-intermediate-risk, high-intermediate-risk, and high risk groups respectively (P = 0.000 0). The 6-year PFS rates were 59.7%, 30.2%, 16.7%, and 10.3% in the low-risk, low intermediate risk, high-intermediate-risk, and high risk groups respectively. The prognosis analysis showed that @entity1349 and PFS were significantly correlated with different clinical characteristics such as stage, PS, number of extra-nodal lesions, LDH bulky disease, and B symptom. CONCLUSION: The treatment with @entity3726 as its main component has a beneficial effect on aggressive @entity1892 in low risk group, but is less effective for the low-intermediate, high-intermediate, and high risk.

[Curative effect on aggressive B cell XXXX and relevant influencing factors of its prognosis, a study of 203 cases].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity706 :: ('MESH:D008223', 'Disease') :: ['immunoblastic lymphoma'] @entity3726 :: ('1649', 'Gene') :: ['CHOP'] @entity1892 :: ('MESH:D016393', 'Disease') :: ['B cell lymphoma'] @entity1893 :: ('MESH:D008228', 'Disease') :: ["non-Hodgkin's lymphoma"] @entity1349 :: ('MESH:D011475', 'Disease') :: ['OS', 'overall survival']
@entity1893 :: (MESH:D008228,Disease) :: ['non-Hodgkin's lymphoma']
