STATEMENT OF PROBLEM: @entity4236 ( @entity4236 ) and ethmoid @entity420 ( @entity420 ) are rare sinonasal malignancies that often involve the skull base. Standard surgical treatment is craniofacial resection (CFR), which allows for efficient removal but entails significant morbidity and mortality. Because expanded endoscopy nasal approaches are newly developed, we aimed to describe the procedure in @entity1 with @entity4236 and @entity420 and compare it with CFR in terms of efficiency and morbidity. METHODS: This work reports on a retrospective series of 16 @entity1 with @entity420 and @entity4236 treated endoscopically with anterior skull-base resection in a single institution over 9 years. Invasion of the frontal sinus, massive extension to the cerebral parenchyma, spread of the @entity5 above the orbits or lysis of anterior facial skeleton were contraindications for endoscopy resection. RESULTS: Of the 16 @entity1 , 11 had @entity420 and 5 @entity4236 . In total, 37.5% (6) exhibited skull-base invasion. All @entity1 had postoperative radiotherapy. In the early postoperative period, one @entity1 experienced delayed @entity410 due to a minor subdural @entity1410 . Two delayed complications were observed: one encephalocele related to inappropriate postoperative care, which required revision surgery, and one extended radionecrosis. Five-year disease-free survival was 83% and 5-year recurrence-free survival 58%. Local control rate was 91% for @entity420 and 100% for @entity4236 . CONCLUSIONS: With low perioperative morbidity and efficient local control, ethmoidectomy combined with anterior skull-base resection is a promising approach for managing selected cases of @entity420 and @entity4236 . These findings need further investigation with prolonged follow-up.

Endoscopy skull-base resection for ethmoid XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumour'] @entity4236 :: ('MESH:D018304', 'Disease') :: ['ON', 'Olfactory neuroblastoma'] @entity1410 :: ('MESH:D006406', 'Disease') :: ['hematoma'] @entity420 :: ('MESH:D000230', 'Disease') :: ['AC', 'adenocarcinoma']
@entity420 :: (MESH:D000230,Disease) :: ['adenocarcinoma and olfactory neuroblastoma']
