UNASSIGNED: A recent meta-analysis found that @entity146 are associated with an increased @entity14 ( @entity14 ) risk. Yet, the finding on TV viewing time, the most widely used surrogate of @entity146 , was based on only two studies. Furthermore, light-intensity activities (e.g., standing and slow walking), non-sedentary by posture but close to @entity146 by Metabolic Equivalent Task values, have not been investigated in relation to @entity14 risk. Thus, we prospectively analyzed the relationships based on 69,715 @entity1 from Nurses' Health Study (1992-2010) and 36,806 @entity1 from Health Professionals Follow-Up Study (1988-2010). Throughout follow-up, time spent on @entity146 including sitting watching TV and on light-intensity activities were assessed repeatedly; incidence of @entity14 was ascertained. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models from each cohort. A total of 1,119 and 913 incident cases were documented from @entity1 and @entity1 , respectively. The multivariable HR comparing   >=    21 versus   <   7 hours/week of sitting watching TV was 1.21 (95% CI=1.02 to 1.43, Ptrend =.01) in @entity1 and 1.06 (95% CI= 0.84 to 1.34, Ptrend =.93) in @entity1 . In @entity1 , those highly sedentary and physically less active had an approximately 41% elevated risk of @entity14 (95% CI=1.03 to 1.92) compared with those less sedentary and physically more active. The other @entity146 and light-intensity activities were not related to @entity14 risk in @entity1 or @entity1 . In conclusion, we found that prolonged sitting time watching TV was associated with an increased @entity14 risk in @entity1 but not in @entity1 . This article is protected by copyright. All rights reserved.

XXXX and light-intensity activities in relation to @entity14 risk.

@entity1 :: ('9606', 'Species') :: ['women', 'men'] @entity14 :: ('MESH:D015179', 'Disease') :: ['CRC', 'colorectal cancer'] @entity146 :: ('MESH:D001523', 'Disease') :: ['sedentary behaviors']
@entity146 :: (MESH:D001523,Disease) :: ['Sedentary behaviors']
