BACKGROUND: There is limited experience on @entity2778 use in the management of childhood @entity943 . This study reviews the results of our experience with oral @entity2778 for treatment and prevention of @entity591 in @entity1 . METHODS: The records of 62 @entity1 (27 female, 35 male, mean age: 8.5+/-5.3 years) treated with @entity2778 for supraventricular or @entity943 from 1994 to 1999 at our institution were reviewed. Demographic, clinical, echocardiographic, electrocardiographic (ECG), ambulatory ECG and electrophysiologic variables were collected. RESULTS: Forty-two (63.6%) @entity1 had re-entrant @entity4710 , eight @entity1 (12.9%) had @entity591 , one @entity1 (1.6%) had junctional ectopic @entity591 , four @entity1 (6.5%) had @entity1165 , and seven @entity1 (11.3%) had complex @entity943 , as evidenced by surface or ambulatory ECG records; or revealed during the electrophysiological study. The mean @entity2778 dose was 3.9+/-1.2 mg/kg per day. In 15.5+/-13.9 months of @entity2778 use 50% (n=31) had complete relief of symptoms and/or @entity943 and 29% (n=18) had partial relief. @entity2778 was ineffective in 20% (n=13). @entity2778 was more effective in re-entrant type @entity4710 (P=0.012). @entity2778 was the first choice in 35.5% of @entity1 . The @entity2778 therapy was initiated in inpatient settings in 40.3% (25 @entity1 ). Complications due to @entity2778 were seen in six @entity1 (five @entity1 developed @entity1168 /pauses, and one @entity1 had @entity1166 ) for which the @entity2778 dose was modified. In @entity1 with @entity1817 , a pacemaker was implanted and in another @entity1 @entity2778 was stopped. CONCLUSION: @entity2778 , being an effective and safe drug particularly in @entity1 , is a good therapeutic alternative for the preventive treatment of childhood @entity591 .

@entity2778 in treatment of pediatric XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'patients', 'patient'] @entity1165 :: ('MESH:D017180', 'Disease') :: ['ventricular tachycardia'] @entity1166 :: ('MESH:D016171', 'Disease') :: ['torsades de pointes'] @entity591 :: ('MESH:D013610', 'Disease') :: ['tachycardia', 'atrial tachycardia', 'tachyarrhythmias'] @entity1817 :: ('MESH:D012804', 'Disease') :: ['sick sinus syndrome'] @entity2778 :: ('MESH:D013015', 'Chemical') :: ['Sotalol', 'sotalol'] @entity4710 :: ('MESH:D013617', 'Disease') :: ['supraventricular tachycardia', 'supraventricular tachycardias'] @entity943 :: ('MESH:D001145', 'Disease') :: ['ventricular arrhythmias', 'arrhythmias', 'arrhythmia'] @entity1168 :: ('MESH:D001919', 'Disease') :: ['bradycardia']
@entity943 :: (MESH:D001145,Disease) :: ['cardiac arrhythmias']
