Resistance to @entity6145 (RTH) is a rare @entity74 . Here in, we report two @entity1 with RTH in whom @entity259 was diagnosed. Two @entity1 were admitted to our clinic and their laboratory results were elevated thyroid hormone levels with unsuppressed TSH. We considered this situation thyroid hormone resistance in the light of laboratory and clinical datas. Thyroid nodule was palpated on physical examination. Thyroid ultrasonography showed multiple nodules in both lobes. Total thyroidectomy was performed. The pathological findings were consistent with @entity7172 . BRAFV600E mutation analysis results were negative. RTH is very rare and might be overlooked. There is no consensus on how to overcome the persistently high TSH in @entity1 with RTH and @entity259 ( @entity259 ). Further studies are needed to explain the relationship between RTH and @entity259 which might be helpful for the treatment of these @entity1 .

XXXX resistance in two @entity1 with @entity7172 and their BRAFV600E mutation status.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity6145 :: ('CHEBI:60311', 'Chemical') :: ['thyroid hormone'] @entity74 :: ('MESH:D030342', 'Disease') :: ['autosomal dominant hereditary disorder'] @entity7172 :: ('MESH:C563277', 'Disease') :: ['papillary thyroid microcarcinoma'] @entity259 :: ('MESH:D013964', 'Disease') :: ['DTC', 'differentiated thyroid cancer']
@entity6145 :: (CHEBI:60311,Chemical) :: ['Thyroid hormone']
