OBJECTIVE: To assess the impact of @entity17389 ( @entity17389 ) on the outcome of pregnancy. DESIGN: Case control study of 137 pregnant @entity1 (cases) and 120 non-pregnant @entity1 (controls) with @entity17389 between 1985 and 1995. SETTING: A rural hospital in Tabora Region, Tanzania. RESULTS: Risk of birth during the attack of @entity17389 was 58.0%, with an extremely high perinatal mortality of 436 per 1000 births. The total loss of pregnancies including abortions was 475. per 1000. Case-fatality rate in pregnant @entity1 was 1.5%, compared to 1.7% in the non-pregnant @entity1 . A @entity137 was seen in 1.5% of the cases and in 1.7% of controls. Relapse rate was 3.6%, compared to 1.7% in non-pregnant @entity1 . Pregnant @entity1 with @entity17389 show higher densities of spirochetes than non-pregnant @entity1 (p < 0.001). The risk of delivery during the attack was positively correlated to increasing density of the spirochetemia (p < 0.001) and to gestational age (p < 0.001). Perinatal @entity204 was related to low birthweight (p < 0.001) and low gestational age (p < 0.001) and not to degree of spirochetemia. CONCLUSIONS: The extremely high perinatal mortality rate during an attack asks for prevention and early effective management of @entity17389 . This is a challenge where access to health services in rural areas of developing countries is hampered by many factors.

XXXX and pregnancy outcome in rural Tanzania.

@entity1 :: ('9606', 'Species') :: ['women'] @entity17389 :: ('MESH:D012061', 'Disease') :: ['TBRF', 'tick-borne relapsing fever'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity137 :: ('MESH:D064420', 'Disease') :: ['Jarisch-Herxheimer reaction']
@entity17389 :: (MESH:D012061,Disease) :: ['Tick-borne relapsing fever']
