@entity2842 ( @entity2842 ) is a chemokine involved in the macrophage infiltration of @entity5 tissue. Tumor associated macrophages (TAMs) are a population of mononuclear-phagocytic cells, which can express complex functions related to @entity5 biology. The present study was designed to analyse the expression of @entity2842 in parenchymal and stromal elements on frozen sections of 27 @entity9962 not otherwise specified (NOS) by immunohistochemistry. The expression of @entity2842 in @entity5 parenchyma and the degree of @entity5 differentiation were assessed. @entity2842 was detected in the @entity513 . Positive immunoreactivity manifested as diffuse, homogeneous, moderate or strong, cytoplasmic staining, confined to @entity5 epithelium. Generally, @entity2842 -negative @entity5 tended to be well differentiated, while chemokine-positive @entity5 exhibited a low level of differentiation. @entity2842 immunoreactivity was also present in TAMs ( @entity469 positive cells) in 23 of 27 @entity5 , and in endothelial cells in 11 of 27 @entity5 . These results indicate that parenchymal and, more variably, stromal elements of @entity1 invasive @entity513 NOS can express @entity2842 in vivo. Additionally, these findings suggest that @entity2842 expression in @entity5 parenchyma is correlated with the histological grade of @entity9962 .

Expression of XXXX in @entity1 invasive ductal breast cancer.

@entity1 :: ('9606', 'Species') :: ['human'] @entity9962 :: ('MESH:D018270', 'Disease') :: ['ductal invasive breast carcinoma', 'breast invasive ductal carcinomas'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'tumors'] @entity469 :: ('968', 'Gene') :: ['CD68'] @entity513 :: ('MESH:D044584', 'Disease') :: ['parenchyma in 15 of 27 ductal carcinomas', 'ductal carcinomas'] @entity2842 :: ('6347', 'Gene') :: ['Monocyte chemotactic protein-1', 'MCP-1']
@entity2842 :: (6347,Gene) :: ['monocyte chemotactic protein-1']
