BACKGROUND: The Global Programme to Eliminate @entity3754 was launched in 2000 with the goal of interrupting transmission of @entity3754 ( @entity3754 ) through multiple rounds of mass drug administration (MDA). In Guinea, there is evidence of ongoing @entity3754 transmission, but little is known about the most densely populated parts of the country, including the capital Conakry. In order to guide the @entity3754 control and elimination efforts, serological and entomological surveys were carried out to determine whether or not @entity3754 transmission occurs in Conakry. METHODS: The prevalence of circulating filarial antigen ( @entity3795 ) of @entity10065 was assessed by an @entity1062 ( @entity1062 ) in @entity1 recruited from all five districts of Conakry. Mosquitoes were collected over a 1-year period, in 195 households in 15 communities. A proportion of mosquitoes were analysed for @entity10065 , using dissection, loop-mediated isothermal amplification (LAMP) assay and conventional polymerase chain reaction (PCR). RESULTS: @entity3795 test revealed no infection in the 611 individuals examined. A total of 14,334 mosquitoes were collected; 14,135 Culex (98.6  %), 161 Anopheles (1.1  %) and a few other species. Out of 1,312 Culex spp. (9.3  %) and 51 An. gambiae (31.7  %) dissected, none was infected with any stage of the @entity10065 parasite. However, the LAMP assay revealed that 1.8  % of An. gambiae and 0.31  % of Culex spp. were positive, while PCR determined respective prevalences of 0  % and 0.19  %. CONCLUSIONS: This study revealed the presence of @entity10065 DNA in mosquitoes, despite the apparent absence of infection in the @entity1 population. Although MDA interventions are not recommended where the prevalence of @entity1062 is below 1  %, the entomological results are suggestive of the circulation of the parasite in the population of Conakry. Therefore, rigorous surveillance is still warranted so that @entity3754 transmission in Conakry would be identified rapidly and adequate responses being implemented.

Assessing the presence of XXXX in vector and @entity1 populations from urban communities in Conakry, Guinea.

@entity1 :: ('9606', 'Species') :: ['human', 'people'] @entity3754 :: ('MESH:D004605', 'Disease') :: ['lymphatic filariasis', 'LF', 'Lymphatic Filariasis'] @entity3795 :: ('31658', 'Species') :: ['CFA'] @entity1062 :: ('MESH:D013736', 'Disease') :: ['immuno-chromatography test', 'ICT'] @entity10065 :: ('6293', 'Species') :: ['W. bancrofti', 'Wuchereria bancrofti']
@entity10065 :: (6293,Species) :: ['Wuchereria bancrofti']
