OBJECTIVE: To study the pathology, imaging and clinical features of a @entity1 with @entity1467 associated @entity401 . METHOD: Data of a case with @entity1467 associated @entity401 confirmed by lung imaging and pathology were collected, analyzed and the related reports in literature were reviewed. RESULT: The @entity1 was a one year and 7 months old @entity1 who suffered from severe @entity55 and recurrent infection during his hospital stay. When his disease was stable, he did not have @entity1353 , but a chest computed tomography (CT) showed ground-glass opacity, regional @entity358 , which indicated @entity401 . Unequal air inflation in bilateral lungs and diffuse overdistension of peripheral air spaces in lung surface were seen through thoracoscope. Pathological examination indicated that @entity133 and alveolar sac were enlarged, alveolar septa was expanded. There were two reports in lung pathology of @entity1467 , @entity851 was seen in 86%-88% cases. The multiple @entity45 in chest CT was characteristic. Clinically, @entity1467 had high morbidity of @entity1729 and progress to @entity1576 frequently. @entity86 was constant which required long duration of respiratory support. CONCLUSION: Trisomy 21 syndrome associated @entity851 were confirmed, which manifest as alveolar simplification in pathology and @entity401 in imaging. The risk of @entity1576 in these cases caused by infection and surgery should be considered.

[Trisomy 21 syndrome associated XXXX : a case report].

@entity1 :: ('9606', 'Species') :: ['patient', 'boy', 'child'] @entity851 :: ('MESH:D006130', 'Disease') :: ['alveolar growth abnormalities'] @entity1353 :: ('MESH:D004417', 'Disease') :: ['shortness of breath and cyanosis'] @entity55 :: ('MESH:D011014', 'Disease') :: ['pneumonia'] @entity133 :: ('MESH:D002282', 'Disease') :: ['alveolar, alveolar ducts'] @entity1467 :: ('MESH:D004314', 'Disease') :: ['trisomy 21 syndrome'] @entity358 :: ('MESH:D008171', 'Disease') :: ['emphysema, band-like change in lung parenchyma'] @entity45 :: ('MESH:D010181', 'Disease') :: ['subpleural cysts'] @entity1729 :: ('MESH:D012141', 'Disease') :: ['respiratory tract infection'] @entity1576 :: ('MESH:D012131', 'Disease') :: ['respiratory failure'] @entity401 :: ('MESH:D017563', 'Disease') :: ['interstitial lung disease', 'interstitial lung diseases'] @entity86 :: ('MESH:D019106', 'Disease') :: ['Prolonged postoperative desaturation']
@entity401 :: (MESH:D017563,Disease) :: ['interstitial lung disease']
