@entity1 with @entity5 are highly susceptible to @entity1031 , which account for a significant percentage of the morbidity and mortality of the disease. Up to 15% of @entity1 with clinically overt @entity5 present with @entity1211 during the course of their disease. Moreover, @entity1 with @entity5 represent 20% of all @entity1 in whom @entity1150 and @entity1151 are diagnosed. This prothrombotic state in @entity5 can occur due to the ability of @entity5 cells to directly activate the blood-clotting cascade and cause @entity715 or induce procoagulant properties and inhibit anticoagulant properties of vascular endothelial cells, platelets, monocytes, and macrophages. It also is well established that this prothrombotic tendency in @entity1 with @entity5 can be enhanced greatly by anticancer treatments, such as surgery and chemotherapy. This phenomenon can be seen in @entity1 with @entity0 , particularly after surgery and chemotherapy. Increased clotting risk also is associated with the use of central venous access devices, commonly used to administer chemotherapeutic agents in @entity1 with @entity5 . @entity715 prophylaxis, therefore, should be considered for @entity1 with @entity0 who are at risk before and during intervention. In the current review, the authors discuss the problem of @entity1031 in @entity1 with @entity0 who are undergoing therapy, the mechanisms by which @entity1031 occur, and the potential strategies by which these events may be prevented. Better understanding of these pathogenetic pathways may lead to the development of more targeted strategies to prevent @entity1031 in @entity1 with @entity5 .

Coagulopathic complications in XXXX .

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'cancer'] @entity1151 :: ('MESH:D011655', 'Disease') :: ['pulmonary embolism'] @entity1150 :: ('MESH:D020246', 'Disease') :: ['deep venous thrombosis'] @entity1031 :: ('MESH:D013923', 'Disease') :: ['thromboembolism', 'thromboembolisms', 'thromboembolic complications'] @entity715 :: ('MESH:D013927', 'Disease') :: ['Thrombosis', 'thrombosis'] @entity1211 :: ('MESH:D054556', 'Disease') :: ['venous thromboembolism']
@entity0 :: (MESH:D001943,Disease) :: ['breast cancer']
