BACKGROUND: @entity1 with @entity1095 have been excluded from initial studies of percutaneous @entity1652 ( @entity1652 ) despite representing a significant proportion of those requiring endovascular intervention. We sought to determine whether these devices could be safely used in @entity1 with @entity1095 . METHODS: @entity1 were stratified into two groups and five subgroups on the basis of indication for arteriography, and they were prospectively randomized at the end of the procedure to receive either the @entity1652 or manual compression. Ankle-brachial index was determined and duplex ultrasound scanning of the accessed femoral artery was performed, before and after the procedure. Ultrasound data included peak systolic velocity, minimum intraluminal vessel diameter, and presence or absence of calcified plaque. Time to hemostasis, ambulation, and discharge were recorded, and major or minor complications were noted. RESULTS: Of 102 @entity1 included in the study, 52 @entity1 were randomized to receive the @entity1652 . There was no difference in ankle-brachial index, minimum intraluminal vessel diameter, or peak systolic velocity in the accessed vessel after closure with @entity1652 or manual compression. Time to hemostasis, ambulation, and discharge was significantly less in the @entity1652 group (P =.001). Presence of calcified plaque was not associated with complications (P =.146). In the @entity1652 group, hemostasis was achieved with 49 of 52 devices (94.2%). There were six complications (5.9%), two of which were major and required operative intervention. All complications were @entity548 and not occlusive. There was no difference in overall complication rate between @entity1652 (7.7%) and manual compression (4.0%) groups (P =.678). No infection was noted in any of the 102 @entity1 . CONCLUSIONS: Suture-mediated percutaneous arterial closure can be safely performed in @entity1 with @entity1095 , even in the presence of calcified plaque. This closure technique enables shorter time to hemostasis, ambulation, and hospital discharge. There are observed differences in minor, but not major, complication rates for MC versus percutaneous arterial closure in @entity1 with @entity1095 , but these differences did not achieve statistical significance in this small series.

Percutaneous arterial closure in XXXX : a prospective randomized evaluation of the Perclose device.

@entity1 :: ('9606', 'Species') :: ['Patients', 'patients'] @entity1652 :: ('MESH:D009471', 'Disease') :: ['SMCD', 'suture-mediated closure devices'] @entity1095 :: ('MESH:D016491', 'Disease') :: ['peripheral vascular disease'] @entity548 :: ('MESH:D006470', 'Disease') :: ['hemorrhagic']
@entity1095 :: (MESH:D016491,Disease) :: ['peripheral vascular disease']
