OBJECTIVES: Deep endovenous stenting to relieve @entity102 ( @entity102 ) secondary to post-thrombotic or non-thrombotic @entity1228 is becoming increasingly well described. However, current and adequately reported systematic reviews on the topic are lacking. This report aimed to produce a systematic review and meta-analysis of the available data, reported to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guideline. METHODS: MEDLINE, EMBASE, and the Cochrane Central Register for Controlled Trials databases and key references were searched. RESULTS: Sixteen studies were included (14 before-and-after studies, 1 controlled before-and-after study, and 1 case series) encompassing successful deep venous stenting in 2,373 and 2,586 post-thrombotic or non-thrombotic limbs and @entity1 respectively. The data were too heterogeneous to perform a meta-analysis. There were significant improvements in validated measures of the severity of @entity102 and @entity66 -specific quality of life. Persistent @entity1066 rates ranged from 56% to 100% in limbs that had often already failed conservative management. Primary and secondary stent patency ranged from 32% to 98.7% and 66%-96% respectively. The major complication rate ranged from 0 to 8.7% per stented limb. A GRADE assessment demonstrated the quality of the evidence for five outcomes to be "Very Low" and one to be "Low" ( @entity1066 ). CONCLUSIONS: The quality of evidence to support the use of deep venous stenting to treat obstructive @entity102 is currently weak. The treatment does however appear promising and is safe and should therefore be considered as a treatment option while the evidence base is improved.

A Systematic Review of Endovenous Stenting in Chronic XXXX Secondary to Iliac Vein Obstruction.

@entity1 :: ('9606', 'Species') :: ['patients'] @entity66 :: ('MESH:D004194', 'Disease') :: ['venous disease'] @entity1066 :: ('MESH:D014456', 'Disease') :: ['ulcer healing'] @entity102 :: ('MESH:D002908', 'Disease') :: ['chronic venous disease', 'CVD'] @entity1228 :: ('MESH:D062108', 'Disease') :: ['iliac vein obstruction']
@entity66 :: (MESH:D004194,Disease) :: ['Venous Disease']
