The combination of axial @entity2473 in clusters, @entity739 , and @entity1155 delay beginning in the first year of life defines @entity739 . @entity2338 remains the choice of treatment for many neurologists. Recent controlled studies support @entity5305 as first-line therapy, and open-label studies suggest that @entity1771 , @entity2812 , and @entity10315 may be useful in treating @entity2473 . Studies regarding the efficacy and safety of such treatments often come from small, uncontrolled trials and are often inconclusive. @entity4677 is effective for treating @entity1625 , but it is uncertain whether it is effective for treating @entity739 . To evaluate the efficacy of @entity4677 monotherapy in newly diagnosed @entity739 , @entity4677 was used initially in the treatment of five @entity1 with @entity739 . On admission, @entity4677 (30 mg/kg) tablets were crushed and administered via nasogastric tube. Two @entity1 were @entity410 free, two @entity1 experienced a 50% reduction in @entity410 frequency, and one @entity1 had no improvement in @entity410 frequency. There were no relapses in the two @entity1 at 6 months after the cessation of @entity410 . It appears that @entity4677 may be effective in the initial treatment of selected @entity1 with @entity739 .

@entity4677 monotherapy in newly diagnosed XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity2338 :: ('MESH:D004393', 'Disease') :: ['Adrenocorticotrophic hormone'] @entity4677 :: ('MESH:C026098', 'Chemical') :: ['levetiracetam', 'Levetiracetam'] @entity1625 :: ('MESH:D004828', 'Disease') :: ['localization-related epilepsy'] @entity410 :: ('MESH:D012640', 'Disease') :: ['seizure', 'seizures'] @entity5305 :: ('MESH:D020888', 'Chemical') :: ['vigabatrin'] @entity10315 :: ('MESH:C022189', 'Chemical') :: ['zonisamide'] @entity739 :: ('MESH:D013036', 'Disease') :: ['hypsarrhythmia', 'cryptogenic West syndrome', 'West syndrome'] @entity2473 :: ('MESH:D013035', 'Disease') :: ['spasms'] @entity1771 :: ('MESH:C052342', 'Chemical') :: ['topiramate'] @entity1155 :: ('MESH:D011596', 'Disease') :: ['psychomotor'] @entity2812 :: ('MESH:C047781', 'Chemical') :: ['lamotrigine']
@entity739 :: (MESH:D013036,Disease) :: ['cryptogenic West syndrome']
