@entity887 in @entity1 with @entity884 may complicate the placement of a cardiac valvular prosthesis. To evaluate the vascular consequences of these emboli, a 15-year review of 102 @entity1 undergoing valve replacement for proven @entity884 was undertaken. Thirty-one @entity1 with 36 episodes of septic embolization were identified. Ten of these were separate extremity occlusive events. All @entity1 with extremity emboli were admitted with @entity158 ; four had limb-threatening emboli. All @entity1 grew gram-positive bacteria from their blood except a single @entity5132 isolate. Appropriate antimicrobial therapy was used in all @entity1 . Angiography confirmed the diagnosis in 11 of 12 @entity1 . Embolic targets included the lower extremities in all except a single instance. Four @entity1 had @entity999 . All but one of the vascular procedures were carried out subsequent to or simultaneously with cardiac valve replacement. Initial operative management included embolectomy (4) and primary amputation (2). Two delayed procedures were required. One @entity1 died. Four @entity1 had limited @entity63 that resolved with antibiotics and anticoagulation. This report suggests that @entity884 requiring valvular replacement is associated with embolization in one third of @entity1 . The presentation of @entity1095 is that of acute extremity @entity63 . The diagnosis should be confirmed by angiography to rule out the possibility of @entity999 . When possible, valve replacement should precede peripheral vascular management, which may include operative or medical components as dictated by the extent of @entity63 .

XXXX complicating @entity884 .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1095 :: ('MESH:D016491', 'Disease') :: ['peripheral vascular emboli'] @entity63 :: ('MESH:D007511', 'Disease') :: ['ischemia', 'limb ischemia'] @entity999 :: ('MESH:D020766', 'Disease') :: ['multiple emboli'] @entity5132 :: ('5476', 'Species') :: ['Candida albicans'] @entity887 :: ('MESH:D004617', 'Disease') :: ['Embolic phenomena'] @entity158 :: ('MESH:D010146', 'Disease') :: ['pain'] @entity884 :: ('MESH:D004696', 'Disease') :: ['infective endocarditis']
@entity887 :: (MESH:D004617,Disease) :: ['Septic embolism']
