Thirty seven @entity1 whose sputum cultures had yielded positive isolates of @entity4507 malmoense during the years 1978-1983 have been reviewed. Significant @entity358 was present in 34 @entity1 (92%), 3 of whom had only single isolates cultured from their sputum. The significance of isolates in the remaining 3 @entity1 was not established. There was pre-existing @entity358 in 22 @entity1 and another 4 were taking immuno-suppressive drugs. Various drug regimens were used to treat the condition but the best responses were seen in 5 @entity1 (13.5%) who received 3 standard drugs given for between 18-24 months. Relapse occurred in 3 of another 5 who were treated with the same combination but given for less than 18 months. Omission of @entity3110 from this standard regimen was associated with an unfavourable course in another 7 @entity1 . Regimens which included the second line drugs @entity8295 and @entity8296 were given to 10 @entity1 . The responses in this group were poor and were probably related to @entity137 and poor @entity1 compliance. Four of these @entity1 eventually underwent successful resectional surgery.

@entity358 with XXXX malmoense--a review of treatment and response.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity3110 :: ('MESH:D004977', 'Chemical') :: ['ethambutol'] @entity8296 :: ('MESH:D003523', 'Chemical') :: ['cycloserine'] @entity137 :: ('MESH:D064420', 'Disease') :: ['drug toxicity'] @entity8295 :: ('MESH:D005000', 'Chemical') :: ['ethionamide'] @entity4507 :: ('MESH:D009164', 'Disease') :: ['Mycobacterium'] @entity358 :: ('MESH:D008171', 'Disease') :: ['pulmonary disease', 'pulmonary infection']
@entity4507 :: (MESH:D009164,Disease) :: ['Mycobacterium']
