BACKGROUND: Mastectomy with immediate breast reconstruction (M+IBR) is performed increasingly for @entity0 treatment, but whether this trend extends to the growing number of @entity1 diagnosed >= age 65 is unknown. We studied the effects of age and comorbidities on the use and outcomes of M+IBR. STUDY DESIGN: @entity1 undergoing mastectomy for @entity0 were ascertained from the National @entity5 Database 2004-2012. Performance of M+IBR and outcomes were compared by age group (<65 versus >= 65) and other @entity1 and @entity5 factors. RESULTS: 364,767 @entity1 underwent mastectomy, of whom 127,501 (35.0%) had IBR. Among M+IBR @entity1 , 10.3% were >= age 65 including 1.5% >= 75. From 2004 to 2012, M+IBR increased from 6.7% to 18.1% in @entity1 >= 65 (p<0.001), paralleling the increase in @entity1 <65 years (32.9% to 57.3%, p<0.001). Contralateral prophylactic mastectomy rates in M+IBR @entity1 were lower in @entity1 >= 65 (27.4%) than <65 (45.9%), p<0.001. A Charlson-Deyo score >0 (any comorbidity) was more frequent in @entity1 >= 65 having mastectomy alone (27.0%) versus M+IBR (18.4 %), p<0.001. Among M+IBR @entity1 , the Charlson-Deyo score was >0 in 18.4% of @entity1 >= 65 versus 9.8% among @entity1 <65, p<0.001. Thirty-day unplanned readmission rates were higher for older @entity1 : 3.7% versus 2.9% for M+IBR @entity1 >= 65 versus <65, respectively, even those with a Charlson-Deyo score=0, 3.5% versus 2.8%, both p<0.001. CONCLUSIONS: M+IBR rates are increasing with 10% of M+IBR @entity1 now >= age 65. Higher 30-day unplanned readmission rates in elderly M+IBR @entity1 with or without comorbidities suggest the need to establish criteria for safe M+IBR in these @entity1 .

Mastectomy and Immediate Breast Reconstruction for XXXX in the Elderly: A National @entity5 Data Base Study.

@entity1 :: ('9606', 'Species') :: ['women', 'Patients', 'patients', 'patient'] @entity5 :: ('MESH:D009369', 'Disease') :: ['tumor', 'Cancer'] @entity0 :: ('MESH:D001943', 'Disease') :: ['breast cancer']
@entity5 :: (MESH:D009369,Disease) :: ['Cancer']
