AIM: To assess whether susceptibility-weighted imaging (SWI) provides better image contrast for the detection of haemorrhagic ischaemia-reperfusion injury in the heart. MATERIALS AND METHODS: Thirty @entity1 (all @entity1 ; mean age 53 years) underwent cardiac magnetic resonance imaging (MRI) within 7 days of primary percutaneous intervention for acute @entity583 ( @entity583 ). Multiple gradient-echo T2* sequences with magnitude and phase reconstructions were acquired. A high-pass filtered phase map was used to create a mask for the SWI reconstructions. The difference in image contrast was assessed in those @entity1 with @entity3885 . A mixed effects regression model was used to test the effect of echo time and reconstruction method on phase and contrast-to-noise ratio (CNR). Medians and interquartile ranges (IQR) are reported. RESULTS: T2* in haemorrhagic @entity1188 was shorter than in non-haemorrhagic @entity1188 (33.5  ms [24.9-43] versus 49.9  ms [44.6-67.6]; p=0.0007). The effect of echo time on phase was significant (p<0.0001), as was the effect of @entity548 on phase (p=0.0016). SWI reconstruction had a significant effect on the CNR at all echo times (echoes 1-5, p<0.0001; echo 6, p=0.01; echo 7, p=0.02). The median echo number at which @entity548 was first visible was less for SWI compared to source images (echo 2 versus echo 5, p=0.0002). CONCLUSION: Cardiac SWI improves the contrast between @entity548 and the surrounding tissue following @entity583 and has potential as a new tool for identifying @entity1 with ischaemia-reperfusion injury.

XXXX : susceptibility-weighted cardiac MRI for the detection of  reperfusion @entity548 at 1.5 T.

@entity1 :: ('9606', 'Species') :: ['patients', 'men'] @entity548 :: ('MESH:D006470', 'Disease') :: ['myocardial haemorrhage', 'haemorrhage'] @entity3885 :: ('MESH:D008173', 'Disease') :: ['microvascular obstruction'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarcts'] @entity583 :: ('MESH:D009203', 'Disease') :: ['STEMI', 'ST elevation myocardial infarction']
@entity583 :: (MESH:D009203,Disease) :: ['Acute myocardial infarction']
