Diet-induced milk fat @entity308 is caused by highly fermentable and high-unsaturated @entity844 (FA) diets, and results in reduced milk fat concentration and yield, reduced de novo FA, and increased trans isomers of the alternate biohydrogenation pathways. The hypothesis of the current experiment was that a diet higher in fermentability and lower in unsaturated FA (UFA) would accelerate recovery compared with a high-UFA and lower-fermentability diet. Eight ruminally cannulated and 9 noncannulated multiparous Holstein @entity291 were randomly assigned to treatment sequences in a replicated Latin square design. During each period milk fat @entity308 was induced for 10 d by feeding a low-fiber, high-UFA diet [25.9% @entity8249 ( @entity8249 ) and 3.3% C18:2]. Following the induction phase, @entity291 were switched to recovery treatments for 18 d designed to correct dietary fermentability, UFA, or both fermentability and UFA concentration. Treatments during recovery were (1) correction of fiber and UFA diet [control; 31.8% @entity8249 and 1.65% C18:2], (2) a diet predominantly correcting fiber, but not UFA [high oil (HO); 31.3% @entity8249 and 2.99% @entity31079 ], and (3) a diet predominantly correcting UFA, but not fiber concentration [ @entity258 ( @entity258 ); 28.4% @entity8249 and 1.71% C18:2]. Milk and milk component yield, milk FA profile, ruminal pH, and 11 rumen microbial taxa were measured every third day during recovery. Milk yield decreased progressively in HO and control, whereas it was maintained in the @entity258 diet. Milk fat concentration increased progressively during recovery in all treatments, but was on average 9% lower in @entity258 than control from d 12 to 18. Milk fat yield increased progressively in all treatments and was not different between control and @entity258 at any time point, but was lower in HO than control on d 15. Milk trans-10 C18:1 and trans-10,cis-12 conjugated @entity4722 decreased progressively in all treatments, but was higher in HO than control from d 3 to 18 [136    50 and 188    57% (mean    SD)], whereas @entity258 caused a smaller increase in these FA compared with control (67    25 and 90    22%). Additionally, milk trans-11 C18:1 and cis-9,trans-11 conjugated @entity4722 was decreased in control and @entity258 and increased in HO during recovery. Selected microbial species observed changed during recovery, but major treatment differences were only observed for Streptococcus bovis. The @entity258 diet that was similar in UFA but 3.4% units lower in @entity8249 compared with to the control had a similar decrease in alternate trans biohydrogenation intermediates in milk. The HO diet that was similar in @entity8249 but 2.0% units higher in UFA compared with the control had higher alternate trans biohydrogenation intermediates in milk compared with control. However, recovery of milk fat yield was similar between treatments at most time points.

Effect of diet fermentability and unsaturated fatty acid concentration on recovery from diet-induced milk fat XXXX .

@entity844 :: ('CHEBI:35366', 'Chemical') :: ['fatty acid'] @entity8249 :: ('MESH:D004916', 'Disease') :: ['neutral detergent fiber', 'NDF'] @entity308 :: ('MESH:D003866', 'Disease') :: ['depression'] @entity258 :: ('MESH:D009800', 'Disease') :: ['LF', 'low fiber'] @entity291 :: ('9913', 'Species') :: ['cows'] @entity4722 :: ('MESH:D019787', 'Chemical') :: ['linoleic acid'] @entity31079 :: ('CHEBI:61159', 'Chemical') :: ['C18:2']
@entity308 :: (MESH:D003866,Disease) :: ['depression']
