A total of 357 clinical @entity4195 isolates collected between 1994 and 1999 in Rio de Janeiro city were tested for susceptibility to 10 antimicrobial drugs by agar-diffusion tests. All isolates were susceptible to @entity114 , cephems, and @entity2176 . High resistance rates were observed for @entity803 (43.1%) and @entity206 / @entity207 (77.9%). Three isolates (0.8%) were resistant to @entity2929 , and three exhibited intermediate susceptibility. Determination of the @entity2929 MICs by the agar dilution method, showed 1.6% of @entity2929 resistant isolates (the three @entity2929 -resistant and the three @entity2929 -intermediate isolates found by agar-diffusion test). Of the @entity2929 -resistant isolates subjected to the double-disc diffusion test for @entity2929 and @entity3402 , three isolates expressed the iMLSB and three the M phenotype. The resistance phenotypes were confirmed by comparing the @entity3402 MICs determined under normal testing conditions and those determined after induction by pre-growth in 0.06 microg/ml of @entity2929 . Three ermTR and three mefA-containing isolates were detected by PCR. In strains belonging to the iMLSB phenotype, two clones were identified by PFGE following restriction with SmaI. M phenotype isolates could not be restricted with SmaI. Our results indicate a low rate of @entity2929 resistance among @entity4195 isolated in Rio de Janeiro, Brazil, and pointed to the presence of both resistance mechanisms found in streptococci.

Antimicrobial susceptibility and survey of macrolide resistance mechanisms among XXXX isolated in Rio de Janeiro, Brazil.

@entity2176 :: ('MESH:D014640', 'Chemical') :: ['vancomycin'] @entity3402 :: ('MESH:D002981', 'Chemical') :: ['clindamycin'] @entity114 :: ('MESH:D010406', 'Chemical') :: ['penicillin'] @entity2929 :: ('MESH:D004917', 'Chemical') :: ['erythromycin'] @entity4195 :: ('1314', 'Species') :: ['Streptococcus pyogenes', 'S. pyogenes'] @entity207 :: ('MESH:D013420', 'Chemical') :: ['sulfamethoxazole'] @entity803 :: ('MESH:D013752', 'Chemical') :: ['tetracycline'] @entity206 :: ('MESH:D014295', 'Chemical') :: ['trimethoprim']
@entity4195 :: (1314,Species) :: ['Streptococcus pyogenes']
