AIM OF THE STUDY: To analyse trends in the incidence rates of @entity420 and @entity957 ( @entity1289 and SCC, respectively) in white @entity1 between 1992 and 2010. MATERIAL AND METHODS: We used data from the Surveillance, Epidemiology, and End Results (SEER program to identify cases of @entity418 ). Age adjusted incidence rates (IR) were calculated for @entity1289 and SCC for two different time periods (1992-1996 and 2006-2010) and stratified by age, stage, and histologic type. We used joinpoint analysis to detect changes in rates between 1992 and 2010. RESULTS: Between the time periods 1992-1996 and 2006-2010, the age-adjusted incidence rates for SCC in white @entity1 decreased from 1.2/100,000 to 0.8/100,000 personyears, and for @entity1289 it increased from 0.5/100,000 to 0.7/100,000 personyears. Similar to white @entity1 , the increase in the incidence of @entity1289 was consistent for all stages and all age groups in white @entity1 . However, it was most pronounced in @entity1 aged 45-59 years, where the incidence of @entity1289 (0.9/100,000 @entity1 -years) in 2006-2010 exceeded the incidence of SCC (0.6/100,000 @entity1 -years). On joinpoint regression analysis, an inflection point was seen in 1999 for @entity1289 , indicating a slower rate of increase for @entity1289 after 1999 (annual percentage change of 8.00 before 1999 vs. 0.88 starting in 1999). CONCLUSIONS: The incidence of @entity1289 is increasing in white @entity1 , irrespective of age or stage. Indeed, @entity1289 is now more common than SCC in white @entity1 between 45 and 59 years of age.

Changing incidence of XXXX among white @entity1 : analysis of SEER data (1992-2010).

@entity1 :: ('9606', 'Species') :: ['women', 'person', 'men'] @entity1289 :: ('1636', 'Gene') :: ['ACE'] @entity957 :: ('MESH:D002294', 'Disease') :: ['squamous cell carcinoma of the oesophagus'] @entity418 :: ('MESH:D004938', 'Disease') :: ['esophageal cancer'] @entity420 :: ('MESH:D000230', 'Disease') :: ['adenocarcinoma']
@entity418 :: (MESH:D004938,Disease) :: ['esophageal cancer']
