OBJECTIVES: To describe the use of laser Doppler velocimetry for measurement of vaginal blood flow and report the effects of @entity172 compared with @entity172 - @entity342 treatment in post-menopausal @entity1 . DESIGN: Literature review of pelvic blood flow studies and sexual function. Findings from a prospective, randomized, parallel study. SETTING: Normal @entity1 volunteers in an academic research environment. INTERVENTIONS: Laser Doppler measurements of vaginal blood flow were compared before and after the administration of oral esterified @entity172 or esterified @entity172 plus @entity8645 for four and eight weeks of daily drug administration. MAIN OUTCOME MEASURES: Vaginal blood flow velocities. RESULTS: Laser Doppler velocimetry proved readily adaptable for measurement of vaginal blood flow. Although esterified @entity172 plus @entity8645 showed greater effects on blood flow than esterified @entity172 alone, the results were not statistically significant. CONCLUSIONS: Vaginal blood flow is an objective measure of sexual function which can be determined with laser Doppler velocimetry. The vasodilator effects of esterified @entity172 and esterified @entity172 with @entity8645 are similar.

Ovarian hormones and vaginal blood flow: using laser Doppler velocimetry to measure effects in a clinical trial of post-menopausal XXXX .

@entity172 :: ('MESH:D004967', 'Chemical') :: ['estrogen', 'estrogens'] @entity1 :: ('9606', 'Species') :: ['women', 'human'] @entity342 :: ('CHEBI:50113', 'Chemical') :: ['androgen'] @entity8645 :: ('MESH:D008777', 'Chemical') :: ['methyltestosterone']
@entity1 :: (9606,Species) :: ['women']
