OBJECTIVE: To optimize the treatment of PQ @entity4968 by a therapeutic regimen designed on the presently available clinical research reports following the principles of evidence-based medicine. METHODS: A treatment plan for a randomly chosen PQ poisoned @entity1 was designed, with regard to the application of blood purification and immunosuppressor, following the suggestions in literatures adopted through computer aided search of Cochrane library (issue 1, 2010), MEDLINE (1950-2010.1) and China Biomedicine Literature Database (CBM, 1978-2010). The systematic evaluations,Meta-analysis and the randomized controlled trials (RCT) on treatment for PQ @entity4968 were collected to guide the design. A one year follow-up was conducted after the discharge of the @entity1 . RESULTS: 7 articles matching the adoption criteria were analyzed. These reports demonstrate that blood purification and glucocorticoid combined with @entity786 are effective against PQ @entity4968 . Blood purification can prolong the survival, but has little effect on mortality, whereas immunosuppressants increase the survival rate. With adjustment to the @entity1 's condition, an evidence-based treatment plan was used for the @entity1 upon her consent. The @entity1 showed significant improvement throughout the hospitalization with no complication found during the follow-up. CONCLUSION: With guidance from the latest research, an evidence-based treatment plan tailored to the @entity1 's specific needs may benefit @entity1 with PQ @entity4968 at least in short term. However, the long term effect of such measure still requires further studies with longer follow-up.

[An evidence-based treatment design for paraquat (PQ) XXXX ].

@entity1 :: ('9606', 'Species') :: ['patient'] @entity786 :: ('MESH:D003520', 'Chemical') :: ['cyclophosphamide'] @entity4968 :: ('MESH:D011041', 'Disease') :: ['poisoning']
@entity4968 :: (MESH:D011041,Disease) :: ['poisoning']
