PURPOSE: Total parenteral nutrition (TPN) has prolonged survival in @entity1 with intestinal failure; however, @entity3851 ( @entity3851 ) may preclude its use. @entity3851 is an indication for isolated liver transplantation (ILT) or @entity8 ( @entity8 ). Isolated liver transplantation for @entity3851 should only be considered in @entity1 who have the potential for enteral autonomy. METHODS: We retrospectively reviewed the records of @entity1 with @entity3851 who underwent ILT (n = 7) or @entity8 (n = 5) between 1994 and 2005. The median age at the time of transplantation was 10.0 months. Intestinal failure followed @entity3166 (n = 3), @entity6675 (n = 3), @entity6675 with @entity3313 (n = 3), @entity6675 with @entity1146 (n = 1), @entity1518 (n = 1), and @entity14873 microcolon @entity1944 (n = 1). RESULTS: Isolated liver transplant @entity1 had a median length of small bowel of 70 cm and tolerated a median of 50% of enteral calories. The median length of small bowel in @entity1 who underwent @entity8 was 29 cm, and none tolerated more than 30% of goal enteral feeds. Reduced-size (n = 5) and whole-liver (n = 2) allografts were used for @entity1 undergoing ILT. @entity1 undergoing @entity8 received liver-small bowel-pancreas (n = 4) or @entity409 (n = 1). Overall @entity1 survival was 57% in ILT (median follow-up = 25.1 months); 3 survivors are TPN independent, and the fourth @entity1 requires TPN 3 days/wk. @entity1 survival was 40% after @entity8 (median follow-up = 13.0 months); 1 @entity8 @entity1 died of abuse 16.9 months after transplant and was TPN independent at the time of @entity204 . Both survivors are TPN independent. @entity648 levels are within normal range in all survivors. CONCLUSION: Isolated liver transplantation for @entity3851 in the setting of intestinal failure is a viable option in @entity1 who have the potential for enteral autonomy. Multivisceral transplantation is the only alternative in @entity1 without the potential for intestinal recovery. Survival can be achieved in @entity1 with @entity3851 , but mortality remains high for both procedures.

Isolated liver and @entity8 for total parenteral nutrition-related XXXX .

@entity1 :: ('9606', 'Species') :: ['children', 'Patients', 'patients', 'patient', 'Patient'] @entity1944 :: ('MESH:D007410', 'Disease') :: ['intestinal hypoperistalsis syndrome'] @entity8 :: ('MESH:D007674', 'Disease') :: ['MVT', 'multivisceral transplantation'] @entity3166 :: ('MESH:D020345', 'Disease') :: ['necrotizing enterocolitis'] @entity3313 :: ('MESH:D045822', 'Disease') :: ['volvulus'] @entity648 :: ('MESH:D001663', 'Chemical') :: ['Bilirubin'] @entity14873 :: ('MESH:C536139', 'Disease') :: ['megacystis'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver-small bowel-pancreas-colon'] @entity1518 :: ('MESH:C562835', 'Disease') :: ['malrotation'] @entity6675 :: ('MESH:D020139', 'Disease') :: ['gastroschisis'] @entity3851 :: ('MESH:D058625', 'Disease') :: ['end-stage liver disease owing to TPN-induced cholestasis', 'ESLD-TPN'] @entity1146 :: ('MESH:D018633', 'Disease') :: ['atresia'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death']
@entity3851 :: (MESH:D058625,Disease) :: ['end-stage liver disease']
