OBJECTIVE: To explore associations between @entity227 , @entity231 , and mortality in older @entity1 after adjusting for other factors associated with mortality. METHODS: A population cohort of 3654 @entity1 aged 49 years or older (82.4% of eligible residents in the Blue Mountains region, west of Sydney, Australia), were examined at the Blue Mountains Eye Study baseline period (1992-1994) and followed up 5 years later (1997-1999). Australian National Death Index data were used to confirm @entity1 who had died since baseline. Associations between mortality and presence of @entity227 and @entity231 at baseline were assessed using the Cox proportional hazards regression model, controlling for age, sex, demographic and socioeconomic status, medical history, and health risk behaviors. RESULTS: By June 30, 1999, 604 @entity1 (16.5%) had died. The age- and sex-standardized 7-year cumulative mortality rate was 26% among @entity1 with any @entity227 and 16% in @entity1 without @entity227 . After adjusting for factors found significantly associated with mortality, including age, male sex, low self-rated health, low socioeconomic status, systemic medical conditions, and negative health risk behaviors, the presence at baseline of any @entity227 was independently associated with increased mortality risk (risk ratio [RR], 1.7; 95% confidence interval, 1.2-2.3). The presence of age-related @entity231 , either nuclear (RR, 1.5), cortical (RR, 1.3), or posterior subcapsular @entity231 (RR, 1.5), was also significantly associated with increased mortality risk. These associations remained statistically significant when @entity227 and each type of @entity231 were included simultaneously in the multivariate Cox model. CONCLUSION: @entity227 and age-related @entity231 may be independent risk factors for increased mortality in older @entity1 .

@entity227 , age-related XXXX , and mortality.

@entity1 :: ('9606', 'Species') :: ['participants', 'persons'] @entity227 :: ('MESH:D014786', 'Disease') :: ['Visual impairment', 'visual impairment'] @entity231 :: ('MESH:D002386', 'Disease') :: ['cataract']
@entity231 :: (MESH:D002386,Disease) :: ['cataract']
