The 1996 Annual Report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) summarizes data voluntarily collected from 130 centers on 4329 @entity1 and adolescent @entity1 who received renal transplants on or after January 1, 1987. This report updates information on transplants; data on dialysis and @entity740 have, for the first time, been reported separately (in submission). The NAPRTCS registry shows that the majority of pediatric renal transplants are performed in @entity1 above 6 years of age (73%). The most frequent diagnoses @entity3551 (16%), @entity8 (16%), and @entity628 (12%). Pre-emptive transplantation was performed in 24% of @entity1 . Triple drug maintenance therapy with @entity229 , @entity205 and @entity500 was used by >70% of all transplant recipients throughout 7 years of follow-up. Fifty-six per cent of transplant recipients were rehospitalized during months 1-5 (51% live donor (LD), 62% @entity20944 ( @entity20944 )), with rejection and infection as the main causes. In the period 30-35 months post-transplant, 19-22% of @entity1 (163 LD, 185 @entity20944 ) were rehospitalized. The median time to the first rejection was 46 days for @entity20944 transplants and 377 days for LD grafts (p<.001). Six-year graft survival rates were 73% and 56% for LD grafts and @entity20944 grafts, respectively (p<.001). The overall growth deficit was constant over a period of 60 months. However, @entity1 transplanted under 5 years of age reduce their height deficit by about one-third compared to an increase in height deficit of up to 22% for older @entity1 . The NAPRTCS data analysis also demonstrates a delay in first rejection episodes in LD compared to @entity20944 transplants, and a steady improvement in @entity20944 graft survival over the past 5 years in pediatric transplant recipients.

Renal transplantation in XXXX from 1987-1996: the 1996 Annual Report of the North American Pediatric Renal Transplant Cooperative Study.

@entity1 :: ('9606', 'Species') :: ['children', 'patients'] @entity3551 :: ('MESH:C536483', 'Disease') :: ['include obstructive uropathy'] @entity8 :: ('MESH:D007674', 'Disease') :: ['aplastic/hypoplastic/dysplastic kidneys'] @entity500 :: ('MESH:D001379', 'Chemical') :: ['azathioprine'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity628 :: ('MESH:D005923', 'Disease') :: ['focal segmental glomerulosclerosis'] @entity740 :: ('MESH:D051436', 'Disease') :: ['chronic renal insufficiency'] @entity205 :: ('MESH:D016572', 'Chemical') :: ['cyclosporine'] @entity20944 :: ('MESH:D002102', 'Disease') :: ['CD', 'cadaver donor']
@entity1 :: (9606,Species) :: ['children']
