OBJECTIVE: To evaluate differences in meniscal T1   and T2 quantification in @entity1 with acute anterior cruciate ligament (ACL) injuries and to determine correlations of these differences with MR morphological grading and @entity1 -reported outcomes. DESIGN: Bilateral knees of 52 @entity1 with @entity131 and 20 healthy controls were scanned using 3  T magnetic resonance imaging (MRI) T1   and T2 mapping in this prospective study. Quantitative analysis of the meniscus was performed in anterior and posterior horns of the lateral and medial menisci. Morphological meniscal damage was assessed using modified whole-organ MRI scores (WORMS). Measurements were compared between injured, uninjured contralateral, and control knees using a mixed-effects regression model. Correlations between meniscal T1  /T2, WORMS and @entity3331 and @entity571 Outcome Scores (KOOS) were examined using partial correlation analysis. RESULTS: Mean meniscal T1   and T2 values were significantly higher in ACL-injured knees compared to control and contralateral knees. Menisci of ACL-injured knees without tears, including those limited to modified meniscal WORMS grade 0, also had significantly higher T1   and T2 values compared to menisci of uninjured knees. Within ACL-injured knees, T1   and T2 values showed significant positive associations with meniscal WORMS and significant negative associations with KOOS. CONCLUSION: Acute @entity130 are associated with significantly increased meniscal T1   and T2 values in both @entity1 with and without @entity75 or tears, suggesting quantitative MRI provides more sensitive measures of meniscal differences compared to traditional morphological MRI sequences. Correlation between meniscal T1  /T2 and KOOS suggest that quantitative MRI is reflective of the extent of @entity1 ' clinical symptoms.

MR T1   and T2 of meniscus after acute anterior cruciate XXXX .

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity131 :: ('MESH:D001930', 'Disease') :: ['acute ACL injury'] @entity571 :: ('MESH:D010003', 'Disease') :: ['Osteoarthritis'] @entity75 :: ('MESH:D001927', 'Disease') :: ['meniscal lesions'] @entity3331 :: ('MESH:D007718', 'Disease') :: ['Knee Injury'] @entity130 :: ('MESH:D014947', 'Disease') :: ['ACL injuries']
@entity130 :: (MESH:D014947,Disease) :: ['ligament injuries']
