OBJECTIVES: The aim of this study was to determine the correlation between coronary artery @entity460 (CAC) scores on 3  mm electrocardiography (ECG)-gated computed tomography (CT) scans and standard 6 mm chest CT scans, and to compare relative strength of associations of CAC on each scan type with mortality risk. BACKGROUND: @entity729 predicts @entity65 ( @entity65 ) and all-cause mortality, and is  typically measured on ECG-gated 3 mm CT scans. @entity1 undergo standard 6 mm chest CTs for various clinical indications much more frequently, but CAC is not usually quantified. To better understand the usefulness of standard  chest CTs to quantify CAC, we conducted a case-control study among @entity1 who had both scan types. METHODS: Between 2000 and 2003, 4,544 community-living individuals self- or physician-referred for "whole-body" CT scans, had 3 mm ECG-gated CTs and standard 6 mm chest CTs, and were followed for mortality through 2009. In this nested case-control study, we identified 157 deaths and 494 controls frequency matched (1:3) on age and sex. The Agatston method quantified CAC on both scan types. Unconditional logistic regression determined associations with mortality, accounting for @entity65 risk factors. RESULTS: @entity1 were 68    11 years of age and 63% male. The Spearman correlation of CAC scores between the 2  scan types was 0.93 (p  < 0.001); median CAC scores were lower on 6 mm CTs compared to 3 mm CTs (22  vs.104 Agatston units, p  < 0.001). Adjusted for traditional @entity65 risk factors, each standard deviation higher CAC  score on 6 mm CTs was associated with 50% higher odds of @entity204 (odds ratio: 1.5; 95% confidence interval: 1.2  to 1.9), similar to 50% higher odds on the 3 mm ECG-gated CTs (odds ratio: 1.5; 95% confidence interval: 1.1  to  1.9). CONCLUSIONS: CAC scores on standard 6 mm chest CTs are strongly correlated with 3 mm ECG-gated CTs and similarly predict mortality in community-living individuals. Chest CTs performed for other clinical indications may provide an  untapped resource to garner @entity65 risk information without additional radiation exposure or expense.

Relationship of Coronary XXXX on Standard Chest CT Scans With Mortality.

@entity1 :: ('9606', 'Species') :: ['Patients', 'Participants', 'persons'] @entity460 :: ('MESH:D002118', 'Chemical') :: ['calcium'] @entity729 :: ('MESH:D061205', 'Disease') :: ['Coronary artery calcification'] @entity204 :: ('MESH:D003643', 'Disease') :: ['death'] @entity65 :: ('MESH:D002318', 'Disease') :: ['CVD', 'cardiovascular disease']
@entity460 :: (MESH:D002118,Chemical) :: ['Calcium']
