Anticoagulant responses to @entity1229 vary among @entity1 , based on genetic factors, diet, concomitant medications, and disease state. We evaluated the effectiveness and safety of a 10mg @entity1229 initiation nomogram in an Asian population. Retrospective cross-sectional audit studies were conducted from March 2009 to March 2010. The use of a 10mg-loading dose to initiate @entity1229 treatment resulted in 33(84.6%) @entity1 attaining a therapeutic INR within four days (mean time, 2.6 days). There was no significant correlation between age, gender, race, and serum albumin for the time to reach a therapeutic INR. A significant correlation was noted for @entity1 's baseline INR and time to reach a therapeutic INR (P<0.05). No significant differences were observed in time to reach a therapeutic INR in @entity1 treated with specific class of concomitant drugs or @entity1 with specific disease states. The overall incidence of over-anticoagulation was 35.9%; however, no @entity548 episodes were encountered. In conclusion, the use of a 10mg @entity1229 nomogram was effective in rapidly achieving a therapeutic INR. However, the nomogram's safety is debatable owing to the high over-anticoagulation rate @entity1229 -administered @entity1 . Caution is recommended in the initiation of @entity1229 treatment using the 10mg nomogram.

Effectiveness and safety of a 10mg XXXX initiation nomogram in asian population.

@entity1 :: ('9606', 'Species') :: ['patients', 'patient'] @entity1229 :: ('MESH:D014859', 'Chemical') :: ['warfarin'] @entity548 :: ('MESH:D006470', 'Disease') :: ['bleeding']
@entity1229 :: (MESH:D014859,Chemical) :: ['warfarin']
