BACKGROUND: A 35-year-old postpartum @entity1 presented with @entity583 ( @entity583 ) due to @entity13865 ( @entity13865 ). In addition to conventional medical therapy, she was treated with immunosuppressive agents ( @entity229 and cytoxan) because of five noncontiguous coronary dissections, surgical inoperability, and @entity951 . Repeat angiography 94 days later demonstrated angiographically normal vessels. METHODS: A literature review of 42 additional cases of peripartum @entity13865 was performed, and the results were compared with this @entity1 . RESULTS: Mortality was 48.8% (21/43). @entity1164 was the initial presentation in 27.9% (12/43) of cases. The left coronary artery was involved in 78.6% (44/56) of dissections with left main segment dissection in 10 cases. In @entity1 who survived > 24 h post @entity1188 , recurrent @entity583 , usually due to a second coronary dissection, occurred in 20.8% (5/24). Histopathologic studies have often shown periadventitial @entity32 (80%, 16/20), in which eosinophils predominate (68.8%, 11/16), and may be linked to the medial degeneration often found in these cases. CONCLUSIONS: The common observation of eosinophilic periadventitial @entity32 suggests a role in the pathophysiology of this rare, yet serious condition. Aggressive immunosuppressive therapy in this case of multivessel dissection resulted in spontaneous angiographic healing of all lesions.

Immunosuppressive therapy for peripartum-type XXXX : case report and review.

@entity1 :: ('9606', 'Species') :: ['women', 'woman', 'patient'] @entity1164 :: ('MESH:D016757', 'Disease') :: ['Sudden cardiac death'] @entity32 :: ('MESH:D007249', 'Disease') :: ['inflammation'] @entity229 :: ('MESH:D011241', 'Chemical') :: ['prednisone'] @entity13865 :: ('MESH:C565153', 'Disease') :: ['SCAD', 'spontaneous coronary artery dissection'] @entity951 :: ('MESH:D000787', 'Disease') :: ['postinfarction angina'] @entity1188 :: ('MESH:D007238', 'Disease') :: ['infarction'] @entity583 :: ('MESH:D009203', 'Disease') :: ['myocardial infarction', 'MI']
@entity13865 :: (MESH:C565153,Disease) :: ['spontaneous coronary artery dissection']
