BACKGROUND _ OBJECTIVE: Many clinic data showed that it is difficult to control primary @entity96 (PLC) by transcatheter arterial chemoembolization ( @entity3375 ) alone due to existence of double blood supply of liver by hepatic artery and portal vein. This study was designed to evaluate the efficacy of transcatheter arterial chemoembolization combined with portal venous chemoembolization (PVCE) in the treatment of moderate and advanced stages of PLC. METHODS: Fifty-eight cases of moderate and advanced stages of PLC were treated with a combination of @entity3375 and PVCE ( @entity3375 ) and 118 @entity1 with moderate and advanced stages of PLC were treated with @entity3375 alone ( @entity3375 group). RESULTS: (1)The total response rates were 86.2% in @entity3375 +PVCE group and 69.5% in @entity3375 group. The remarkable response rates were 31.0 % in @entity3375 and 13.6% in @entity3375 group (P< 0.05). (2)The half-year survival rates were 93.1% in @entity3375 and 72.0% in @entity3375 group (P< 0.05). The 1-year survival rates were 43.1% in @entity3375 and 51.7% in @entity3375 group. The 4-year survival rates were 6.9% in @entity3375 and 5.1% in @entity3375 group (P >0.05). (3) Side effects included @entity221 , bellyache, white blood cell drop, hypohepatia, @entity1087 ,and @entity843 . The degree of @entity409 was positively associated with the amount of iodized oil. CONCLUSION: The combination of @entity3375 and PVCE appears to promote the short-term efficacy but not the long-term efficacy, compared with @entity3375 alone for @entity1 with moderate and advanced PLC.

[Comparison of therapeutic effects between transcatheter arterial chemoembolization and transcatheter arterial-portal venous double chemoembolization in treatment of moderate and advanced stages of primary XXXX ].

@entity1 :: ('9606', 'Species') :: ['patients'] @entity3375 :: ('6868', 'Gene') :: ['TACE', 'TACE/PVCE group'] @entity1087 :: ('MESH:D007565', 'Disease') :: ['jaundice'] @entity96 :: ('MESH:D008113', 'Disease') :: ['liver carcinoma'] @entity843 :: ('MESH:D001201', 'Disease') :: ['ascites'] @entity409 :: ('MESH:D008107', 'Disease') :: ['liver damage'] @entity221 :: ('MESH:D005334', 'Disease') :: ['fever']
@entity96 :: (MESH:D008113,Disease) :: ['liver carcinoma']
