Scopolamine Patch and Acupressure Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean Section
Condition: Nausea; Vomiting; Satisfaction
MeSH terms: Nausea; Vomiting
Intervention: scopolamine patch; acupressure point P6
Intervention description: Group I (n=80): Will receive scopolamine patch placement on the skin behind the right ear 1 hour before initiation of the regional anesthesia for the duration of surgery. The time of the application of the patch will be recorded, and the time of the start of the surgery will be recorded. The last time point for evaluation of patient's nausea/vomiting will be when the patient arrives to the post anesthesia care unit. A member of the research team will remove the patch from the patient and properly dispose the patch upon arrival to the post anesthesia care unit.; Group II (n=80): Will receive acupressure point P6 stimulation. This is a stimulation of the chi channel at the master of the heart (MH8 position) at the small depression of the volar surface of the distal right forearm just above the crest of the wrist. The device will be put on the patients in the operating room prior to administration of the regional anesthesia and will be removed after the cesarean section is complete. The device will be removed from the patient in the operating room, before the patient is transported to the recovery room. Patients will receive continuous stimulation at a level that is comfortable for her prior to administration of the standardized regional anesthesia.
Intervention MeSH terms: Scopolamine; Butylscopolammonium Bromide
Phase: Phase 4
Study type: Interventional
Primary purpose: Prevention
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Enrollment: 240.0
Sex: Female
Minimum age: 18 Years
Maximum age: 45 Years
Healthy volunteers: Accepts Healthy Volunteers
Keywords: cesarean section; acupressure point p6; scopolamine patch

Summary:

      The purpose of this study is to compare the effectiveness of reducing intra-cesarean section
      nausea and vomiting with regional anesthesia in subjects who will receive scopolamine patch
      with acupressure point P6 stimulation versus subjects that receive just scopolamine patch
      versus subjects that receive just acupressure point P6 stimulation.
    

Eligibility criteria:

        Inclusion Criteria:

          1. Female subjects ages 18 to 45

          2. Subjects with ASA Class I or II

          3. Subjects with elective primary or repeat cesarean delivery

          4. Subjects who receive spinal and/or epidural anesthesia

          5. English and non-English speaking subjects will be included in the study

        Exclusion Criteria:

          1. Female subjects <18 years of age

          2. Subjects requiring emergent cesarean delivery

          3. Gestational age < 37 weeks

          4. History of placenta accreta

          5. Multiple gestation pregnancy

          6. ASA status III or higher

          7. Current history of pregnancy induced hypertension, pre-eclampsia, or eclampsia

          8. History of any chronic medication use (other than prenatal vitamins), including
             inhaler medications

          9. Current urinary tract infection, pneumonia, or otitis media

         10. Coagulopathies or skin infections overlying the spine

         11. History of open angle glaucoma, seizures or psychosis