Combined Bleaching Technique: Efficacy and Tooth Sensitivity
Condition: Tooth Bleaching; Tooth Sensitivity
MeSH terms: Dentin Sensitivity; Hypersensitivity
Intervention: Combined Bleaching(2x20); Combined Bleaching(2x20) with arginine; Combined Bleaching (1x20); Combined Bleaching(1x20) with arginine; 8% arginine and calcium carbonate
Intervention description: one clinical session with two applications of 35% hydrogen peroxide of 20 minutes each. 10% carbamide peroxide for two hours daily over the course of two weeks.; one clinical session with two applications of 35% hydrogen peroxide of 20 minutes each. 10% carbamide peroxide for two hours daily over the course of two weeks.; one clinical session with one application of 35% hydrogen peroxide of 20 minutes each. 10% carbamide peroxide for two hours daily over the course of two weeks.; one clinical session with one application of 35% hydrogen peroxide of 20 minutes each. 10% carbamide peroxide for two hours daily over the course of two weeks.; using during all the treatment.
Intervention MeSH terms: Calcium Carbonate; Calcium
Phase: Phase 4
Study type: Interventional
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Investigator)
Enrollment: 108.0
Sex: All
Minimum age: 18 Years
Maximum age: 35 Years
Healthy volunteers: Accepts Healthy Volunteers

Summary:

      The aim of this clinical study is to evaluate the efficacy and dental sensitivity associated
      with Combined Bleaching Technique (in-office + at-home) varying in-office bleaching
      application under two different time protocols, and dentifrice containing arginine 8% and
      carbonate calcium use. One hundred eight participants who meet the study inclusion criteria
      will be selected. The desensitizing agent used will be a dentifrice containing 8% arginine
      and calcium carbonate. In each evaluation will be determined: tooth sensitivity and color.
      The data collected will be submitted to the factorial statistical analysis for evaluation of
      color and chi-square test for tooth sensitivity (α = 5%).
    

Eligibility criteria:

        Inclusion Criteria:

          -  Upper and lower anterior teeth without restorations;

          -  Upper and lower anterior teeth that have never undergone a bleaching procedure and are
             A2 or darker in color compared to the Vita Classical).

        Exclusion Criteria:

          -  Presence of primary and/or secondary carious lesion (s) on upper and lower anterior
             teeth;

          -  Presence of non-carious lesions, such as abfraction, erosion and abrasion;

          -  Presence of clinically visible cracks or defects of dental enamel on the dental
             surfaces of the upper and lower anterior teeth;

          -  Use of fixed orthodontic appliances;

          -  Presence of tooth sensitivity classified as equal to or greater than mild;

          -  Presence of severe dental dimming;

          -  Presence of parafunctional habits;

          -  Presence of any oral pathology;

          -  Smokers;

          -  pregnant and lactating women