Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury
Condition: Depression; Self-injurious Behavior
MeSH terms: Depression; Self-Injurious Behavior
Intervention: Interpersonal Psychotherapy for Depressed Adolescents
Intervention description: Open clinical trial of IPT-ASI for depressed and self-injuring adolescents, 12-18 years. Goal is to assess feasibility of using IPT-A protocol for teens with co-morbid depression and self-injury. All eligible participants receive 12 weeks of individual IPT-ASI with optional monthly booster sessions. IPT-ASI is a psychosocial intervention that focuses on the importance of interpersonal relationships in relation to psychological functioning. The first phase (4 weeks) includes a review of depression and self-injury symptoms, psycho-education about depression and self-injury, and a detailed assessment of the patient's important interpersonal relationships. The middle phase (weeks 5-9) involves interpersonal skill building, including communication skills, affect identification and expression, problem solving. The final phase ( weeks 10-12) involves review of skills, generalization of skills to other relationships, termination.
Phase: Phase 1
Study type: Interventional
Primary purpose: Treatment
Allocation: Non-Randomized
Intervention model: Single Group Assignment
Masking: None (Open Label)
Enrollment: 10.0
Sex: All
Minimum age: 12 Years
Maximum age: 18 Years
Healthy volunteers: No
Keywords: self-injurious behavior; depression; adolescents; psychotherapy

Summary:

      The purpose of this study is to examine the feasibility of using Interpersonal Psychotherapy
      for Depressed Adolescents (IPT-A) to treat adolescents who are experiencing symptoms of
      depression and are engaging in non-suicidal self-injurious behaviors. The trial will include
      recruiting 10 particpants, administering 12-sessions of individual IPT-A, and determining how
      the IPT-A protocol needs to be amended to adequately address the self-injury in addition to
      depression.
    

Eligibility criteria:

        Inclusion Criteria:

          1. 12 to 18 years of age

          2. Diagnosis of MDD, Dysthymic Disorder, Depressive Disorder NOS, Adjustment Disorder
             with depressed Mood

          3. Non-suicidal self-injurious behavior

          4. CDRS >= 36

          5. C-GAS <= 65

          6. English speaking patient

          7. One English speaking caregiver -

        Exclusion Criteria:

          1. Suicide attempt within past 6 months or actively suicidal

          2. Severe incident of non-suicidal self-injury in past 3 months

          3. Severe episode of MDD

          4. Treatment resistant non-suicidal self-injury

          5. Frequent non-suicidal self-injury

          6. Mentally retarded

          7. Current diagnosis of: PTSD, OCD, Schizophrenia, Bipolar Disorder, Psychosis, Substance
             Dependence, ADHD

          8. Current substance use

          9. Currently in active treatment for same condition

         10. Currently taking antidepressant medication

         11. Medical illness likely to interfere with treatment -