PROUD Study - Preventing Opioid Use Disorders
Condition: Anesthesia; Opioid Use
MeSH terms: Opioid-Related Disorders
Intervention: Guided mindfulness exercises; Self-administered aromatherapy; Baby aspirin; Tylenol/Acetaminophen; Pregabalin; Prednisone; Meloxicam; Prilosec; Tramadol; Voltaren; Zofran; Pepcid; Reglan; Versed; Lidocaine; Propofol; Ancef; Tranexamic Acid (TXA); Decadron; Bupivacaine hydrochloride; Toradol
Intervention description: Guided Meditation twice daily; Self-administered aromatherapy every 6 hours and at bedtime; Baby aspirin 81mg: Twice daily for 6 weeks after surgery; Tylenol/Acetaminophen 1000mg: Pre-operative one dose; Every 8 hours for three weeks after surgery; Pregabalin 25mg:
Twice a day for two weeks before surgery; Pre-operative 25-100 mg; Twice a day for two weeks after surgery; Prednisone 5mg: Daily for three weeks after surgery; Meloxicam 7.5mg:
Twice a day, with food, for two weeks before surgery; Twice a day, with food, for two weeks after surgery; Prilosec 20mg:
Daily for two weeks before surgery; Daily for for two weeks after surgery; Rescue pain medicine Tramadol 50mg up to three times a day as needed will be provided for rescue pain; Voltaren 1% topical arthritis gel up to 4 times daily pre-operative only; Zofran 4 mg pre-operative; Pepcid 20 mg pre-operative; Reglan 10 mg pre-operative; Versed 2 mg pre-operative; Lidocaine (preservative free) height based dosing for subarachnoid block intraoperatively; Propofol 10-125 mcg/kg/min intraoperative; Ancef 2-3 gm weight-based dosing intraoperative; Tranexamic Acid (TXA) 2 gm intraoperative; Decadron 10 mg intraoperative; Local anaesthetic 0.5% bupivacaine hydrochloride intraoperative; Toradol nonsteroidal anti-inflammatory drug max 30 mg intraoperative
Intervention MeSH terms: Aspirin; Acetaminophen; Prednisone; Ketorolac Tromethamine; Meloxicam; Diclofenac; Lidocaine; Pregabalin; Tramadol; Bupivacaine; Propofol; Omeprazole; Tranexamic Acid
Phase: Phase 4
Study type: Interventional
Primary purpose: Treatment
Allocation: Non-Randomized
Intervention model: Single Group Assignment
Intervention model description: Matched Prospective Case with Retrospective Control Study and Staff Survey
Masking: None (Open Label)
Enrollment: 57.0
Sex: All
Minimum age: 18 Years
Healthy volunteers: No
Keywords: Hip replacement; Opioid free; Perioperative period; Team work

Summary:

      The objective of this study is to pilot an opioid free anesthetic protocol for patients
      undergoing total hip replacement.
    

Eligibility criteria:

        Inclusion Criteria Intervention group:

          -  Prospective study participants undergoing unilateral total hip replacement surgery
             between the months of February through May, 2021

        Inclusion Criteria Control:

          -  Retrospective controls selected from the Emory Healthcare System Clinical Data
             Warehouse that underwent unilateral total hip replacement surgery between the months
             of February through May, 2020

        Inclusion Criteria Professional Staff:

          -  All staff that participate in the implementation of the opioid free surgical protocol.

        Exclusion Criteria:

          -  Participants that do not speak English will not be eligible for participation in the
             study.

          -  Individuals less than 18 years of age will not be included for participation in the
             study.

          -  Individuals with cognitive impairment or the inability to provide informed consent
             will not be included in the study.