Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone
Condition: Tenosynovitis
MeSH terms: Tenosynovitis
Intervention: Treatment Group: Corticosteroid injection; Control Group (corticosteroid alone); Treatment Group: Lidocaine
Intervention description: Subjects will receive a corticosteroid injection that is 40 mg/mL injection of Methylprednisolone or 40mg/mL injection of methylacetate injectable suspension or 40 mg/mL triamcinolone.; Control Group (corticosteroid alone) subjects will receive (40 mg/mL injection of Methylprednisolone acetate injectable suspension or 40 mg/mL triamcinolone) .; Subjects will receive an injection of lidocaine (1% lidocaine HCl).
Intervention MeSH terms: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Lidocaine; Prednisolone hemisuccinate; Prednisolone phosphate
Phase: Phase 4
Study type: Interventional
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Randomized, unblinded controlled clinical trial
Masking: None (Open Label)
Enrollment: 62.0
Sex: All
Minimum age: 18 Years
Maximum age: 95 Years
Healthy volunteers: No
Keywords: orthopedic disorders; corticosteroids(CS); Lidocaine; Injections

Summary:

      The clinical trial is a randomized control trial to compare the efficacy of a combined
      lidocaine and corticosteroid (CS) injection versus a corticosteroid injection (CS) alone on
      pain, range of motion, and patient reported outcomes for the treatment of common upper
      extremity tendinopathies and nerve entrapments that are often treated with a combination of
      these injectates.
    

Eligibility criteria:

        Inclusion Criteria:

          -  All adult clinical patients of Emory upper extremity surgeons undergoing injection for
             treatment of the following who are willing to participate in the study will be
             included in the study: Tenosynovitis of the upper extremity, including but not limited
             to, the shoulder, biceps, elbow, wrist, thumb, carpometacarpal, midcarpal, elbow, and
             small joints of the hand.

          -  Between the ages of 18 years and 95 years.

          -  For trigger finger: patients with a diagnosis of stenosing tenosynovitis based on a
             history of triggering and the presence of tenderness over the A1 pulley upon clinical
             examination. All patients, based on the Quinnell grading of trigger finger will be
             included.

        Exclusion Criteria:

          -  Patients who are minors, vulnerable subjects, or who are not willing to consent to
             participate in the study.

          -  Allergies to glucocorticoids, current daily use of glucocorticoids or strong opioids
             (morphine, fentanyl, hydromorphone, ketobemidone, methadone, nicomorphine, oxycodone,
             and meperidine), severe diabetic neuropathy of the hand influencing pain perception,
             rheumatoid arthritis, and neurological or psychiatric diseases, potentially
             influencing pain perception.

          -  Subjects who, in the opinion of the investigator, may be non-compliant with study
             schedules or procedures.