bioihbjkbjnl/mcl2 huggingface dataset:
Collection of Gingival Crevicular Fluid From Periodontitis Patients
Condition: Gingival Diseases
MeSH terms: Periodontitis; Gingival Diseases
Study type: Interventional
Phase: Phase 3

Summary: 
      To collect GCF (gingival crevicular fluid) samples from diseased patients suffering only from
      gingivitis and/or periodontitis.
    


Intervention name(s): Fluoride; Fluoride, triclosan
Intervention type(s): Drug; Drug
Intervention description(s): Brush twice daily for 6 weeks; Brush twice daily
Other intervention name(s): Coglate Great Regular Flavor toothpaste; Colgate Total toothpaste
Intervention MeSH terms: Triclosan; Fluorides
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Treatment
Women's-Specific Footwear With Prosthetic Feet
Condition: Lower Limb Amputation Below Knee (Injury); Lower Limb Amputation Above Knee (Injury)
MeSH terms: Wounds and Injuries
Study type: Observational

Summary: 
      The purpose of this study is to address footwear challenges unique to women prosthesis users.
      Comparing the effectiveness of different footwear and prosthesis combinations will help guide
      clinical decision making regarding the prescription of prosthetic devices, while keeping what
      the patient wants in mind.

      It is expected that these results will be used to generate new knowledge for the development
      of versatile prosthetic devices that accommodate a user's unique lifestyle while helping the
      patient to make good progress in rehabilitation.

      Investigators will characterize perceived limitations in footwear among women prosthesis
      users. Investigators think that women prosthesis users will be restricted in footwear choices
      and clothing choices due to the use of a prosthetic device.

      Specifically, investigators expect perceived limitations in footwear will be greater for
      shoes with higher heels than shoes without heels.
    

Detailed description: 
      The project involves development, distribution, and analysis of a questionnaire designed to
      address footwear use among women lower limb prosthesis users. Responses from sixty women with
      a lower extremity amputation will be targeted. VA participants will be identified by the
      MVAHCS. These potential participants will receive the IRB-approved survey via mail. Eligible
      participants include women with unilateral or bilateral lower extremity amputations.

      The questionnaire will target the types of footwear worn by prosthesis users and the types of
      footwear desired to be worn. It will also capture the various types of prosthetic feet worn
      in each footwear category, amputation type, time spent walking in a prosthetic device, and
      general satisfaction with the prosthesis function during daily living when worn with shoes.
    

Intervention name(s): Questionnaire
Intervention type(s): Other
Intervention description(s): This is a questionnaire developed by DoD and VA researchers specifically for this study.
Other intervention name(s): "WSF Questionnaire"
Observational model: Cohort
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        Women Veterans with Lower Limb Amputation (excluding Syme's and Hip Disarticulation)
      
Keywords: Limb Prosthesis; Shoe; Self Concepts
Comparing Cold Biopsy Forceps Versus Cold Snare Biopsy for Colon Polyps
Condition: Colon Polyps
MeSH terms: Polyps; Colonic Polyps
Study type: Interventional

Summary: 
      Comparing the efficacy of cold biopsy forceps versus cold snare biopsy for removing colon
      polyps.
    

Detailed description: 
      Polyps were randomized to be treated with either CSP or CFP. After the initial polypectomy,
      additional EMR was performed at the polypectomy site to assess the presence of residual polyp
      tissue.
    

Intervention name(s): Cold Biopsy forceps; Cold snare biopsy
Intervention type(s): Procedure; Procedure
Intervention description(s): removal of polyps using cold biopsy forceps; Removal of colon polyps using cold snare biopsy
Allocation: Randomized
Intervention model: Single Group Assignment
Masking: Single (Participant)
Primary purpose: Treatment
Keywords: cold biopsy forceps; cold snare biopsy
Gelesis Glycemic Index Study
Condition: Obesity; Diabetes; PreDiabetes
MeSH terms: Prediabetic State
Study type: Interventional

Summary: 
      A study to determine glucose and insulin responses to 50g and 100 g of carbohydrate with and
      without Gelesis200.
    

Detailed description: 
      This will be a single centre, open-label, randomized, single-administration, 4-period, 4-way,
      crossover, pilot study with glycemic and insulin assessments. There is also an option for 2
      additional single-administration periods based on the results of an interim analysis.

      The study includes 2 treatments arms with Gelesis200 (4.20 g 10 minutes before a 50 g
      carbohydrate breakfast and 4.20 g 10 minutes before a 100 g carbohydrate breakfast) plus 2
      control arms consisting of consumption of the breakfasts with water only.

      The optional periods consist of 1 treatment arm with Gelesis200 and 1 control arm with
      breakfast and water only. Either only one or both the optional periods may be conducted. The
      number of additional period(s) to conduct, the amount of Gelesis200 in the treatment arm, as
      well as the meal composition will be based on interim analysis results.
    

Intervention name(s): Gelesis200; Water, only (placebo)
Intervention type(s): Device; Other
Intervention description(s): Encapsulated hydrogel; 300 mL of water
Allocation: Randomized
Intervention model: Crossover Assignment
Intervention model description: 4-way crossover with the option for 2 more crossover arms after interim analysis
Masking: None (Open Label)
Primary purpose: Prevention
Project RESIST: Increasing Resistance to Tobacco Marketing Among Young Adult Sexual Minority Women Using Inoculation Message Approaches
Condition: Cigarette Smoking Behavior
Study type: Interventional

Summary: 
      Project RESIST is an R01 study funded by NCI focused on determining the effects of using
      culturally tailored inoculation approaches to increase resilience to tobacco marketing
      influences among young adult sexual minority women ages 18-30 and incorporates critical
      stakeholder inputs that support later adoption and implementation. The study team is
      utilizing formative research to design and pre-test anti-smoking messages and two national
      longitudinal online survey experiments.
    

Detailed description: 
      This study will recruit 2000 young adult sexual minority women (SMW), ages 18-30 years,
      current smokers (n = 1000) and not current smokers (n=1000). The study team will randomly
      assign participants to a condition in which they will be exposed to either culturally
      tailored anti-smoking messages or non-tailored. Participants will receive these messages at
      baseline and 1, 2, and 3 weeks post baseline. They will be asked to complete a follow-up
      survey one month post baseline. Intentions to quit smoking as well as intention (among
      current smokers) and intention to purchase cigarettes (among current nonsmokers) will be
      measured at baseline and one-month post baseline.
    

Intervention name(s): Culturally tailored anti-smoking messages; Non-culturally tailored interventions
Intervention type(s): Other; Other
Intervention description(s): Anti-smoking messages that are culturally tailored for sexual minority women.; Anti-smoking messages that are not culturally tailored for sexual minority women.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Participants will be randomly assigned to the tailored or non-tailored arms using random assignment function within survey software.
Masking: Single (Participant)
Primary purpose: Other
Safety and Immunogenicity of a TNFa Kinoid in Patients With Crohn's Disease
Condition: Crohn's Disease
MeSH terms: Crohn Disease
Study type: Interventional
Phase: Phase 1/Phase 2

Summary: 
      Evaluation of the safety and the immune response induced by active immunization through a
      TNFa kinoid in patients with Crohn's disease.
    


Intervention name(s): TNFa Kinoid
Intervention type(s): Biological
Intervention description(s): TNFa kinoid at days 0, 7, 28
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: anti-TNFa; immunization; kinoid; crohn's disease
Reformative Versus Single Step Dilation Percutaneous Dilatational Tracheostomy
Condition: Respiratory Failure; Respiratory Depression
MeSH terms: Respiratory Insufficiency
Study type: Interventional

Summary: 
      Percutaneous dilatational tracheostomy (PDT), especially single-step dilatational
      tracheostomy (sd-PDT), is now frequently preferred to surgical tracheostomy. Occasionally, it
      needs a second dilation maneuver .Dissection of the deep cervical fascia during PDT, known as
      reformative PDT (re-PDT), may facilitate the procedure. This study was designed to compare
      re-PDT with sd-PDT in ICU patients
    

Detailed description: 
      Percutaneous dilatational tracheostomy (PDT) is a popular airway management technique in the
      intensive care unit (ICU).Occasionally the first dilation may be challenging when using
      Ciaglia and colleagues' method, and a second dilation may be needed to insert the
      tracheostomy tube. In these circumstances, potentially life-threatening complications, such
      as hemorrhage and hypoxia, may arise. The investigators found the reasons for difficulty in
      achieving smooth dilation of the stoma.The investigators compared the traditional method with
      the improved method.
    

Intervention name(s): reformative dilation technique
Intervention type(s): Procedure
Intervention description(s): reformative dilation technique was used when operating tracheostomy
Other intervention name(s): reformative tracheostomy
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary purpose: Treatment
Keywords: tracheostomy，fascia，force gauge
Gastric Sonography in the Fasted Term Pregnant Patient for Elective Cesarean Delivery
Condition: Respiratory Aspiration; Pregnancy
MeSH terms: Respiratory Aspiration
Study type: Observational

Summary: 
      Food residue in the stomach of patients scheduled to have surgery is considered a major risk
      factor for pulmonary aspiration of gastric contents. The resulting respiratory compromise
      after aspiration is associated with significant morbidity and mortality. The risk of
      pulmonary aspiration is especially important in pregnant women, as they may often require
      surgery without having observed appropriate fasting. In pregnant patients scheduled for
      elective surgery, standard preoperative guidelines apply as the general non-pregnant surgical
      population (8-hour fasting of solid food and 2-hour fasting of clear fluids). A bedside
      ultrasound assessment of the status of the gastric content and volume would be of great value
      for the clinician. This technique has recently been shown very promising in fasted
      non-pregnant patients scheduled for elective surgery. Therefore, it is important to study its
      feasibility in the pregnant population scheduled for elective Cesarean Delivery.

      The investigators hypothesize that no residual solid contents will be found in the gastric
      sonography, and a small volume of gastric fluid will be observed in the antrum in both supine
      and right lateral decubitus.
    

Detailed description: 
      The aim of this prospective study is to provide a qualitative and quantitative description of
      the sonographic appearance of the gastric antrum in fasted pregnant undergoing elective
      Cesarean delivery.

      The investigators expect that the information obtained from the systematic ultrasonographic
      qualitative/quantitative assessment of the gastric content may help anesthesiologist to
      better assess aspiration risk and guide anesthetic and airway management, particularly in
      pregnant women scheduled for elective Cesarean delivery after standard preoperative fasting
      guidelines.
    

Intervention name(s): Ultrasound
Intervention type(s): Device
Intervention description(s): Two-dimensional portable ultrasound unit with a low frequency (2-5 MHz) curved array transducer
Observational model: Case-Only
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        Term pregnant patients who have scheduled elective cesearean sections.
      
Keywords: Respiratory Aspiration; Pregnancy; Ultrasound; Gastric Contents
Assessment of the Acute Effect of IP
Condition: Deficiency Growth Hormone
Study type: Interventional

Summary: 
      It is a nutraceutical system, consisting of oral tablet and an oral spray called Alpha GPC,
      which helps your body naturally restore the HGH levels.
    


Intervention name(s): Placebo; IP
Intervention type(s): Dietary Supplement; Dietary Supplement
Intervention description(s): Beige-brown powder with speckles in clear enteric coated caplet with berry flavor liquid.; Beige-brown powder with speckles in clear enteric coated caplet with berry flavor liquid.
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary purpose: Supportive Care
A Study to Evaluate Androderm®'s Effect on Blood Pressure in Adult Hypogonodal Male Participants
Condition: Hypogonadism
MeSH terms: Hypogonadism
Study type: Interventional
Phase: Phase 4

Summary: 
      This study will evaluate the effect of a once daily Androderm® dose on Blood Pressure (BP) in
      adult hypogonadal men as measured by 24-hour ABPM.
    


Intervention name(s): Androderm®
Intervention type(s): Drug
Intervention description(s): Androderm® transdermal dose.
Intervention MeSH terms: Testosterone
Intervention model: Single Group Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Long-term Outcome in Pediatric Surgical Bypass Grafting After Traumatic Injury and Tumor Resection
Condition: Child Health; Bypass Graft Occlusion
MeSH terms: Wounds and Injuries
Study type: Observational

Summary: 
      Introduction:

      Vascular bypass surgery in children differs significantly from adults. It is a rarely
      performed procedure in the setting of trauma and tumor surgery to facilitate limb salvage.
      Beside the technical challenges to reconstruct the small and spastic vessels, bypass grafting
      should not impede growth of the extremity. The primary aim of this study was to assess
      long-term outcome after pediatric bypass grafting, in a single academic center, focusing on
      potential effects on limb development.

      Methods:

      In this retrospective cohort analyses we included all pediatric patients undergoing vascular
      bypass grafting at the Medical University of Vienna between 2002-2017. All patients ≤ 18
      years suffered a traumatic injury or underwent a tumor resection of the lower or upper limb,
      respectively. The youngest female patient was 0.4 years, the youngest male patient was 3.5
      years.
    


Intervention name(s): pediatric vascular bypass grafting
Intervention type(s): Procedure
Intervention description(s): pediatric vascular bypass grafting
Observational model: Cohort
Time perspective: Retrospective
Sampling method: Non-Probability Sample
Study population: 
        This study represents a retrospective cohort analysis of pediatric patients who underwent
        vascular bypass grafting by an experienced team of vascular surgeons at the Medical
        University Vienna between 2002-2017.

        All data regarding demographics, operative techniques and outcome were collected from the
        in-hospital database registry in collaboration with the Department of Orthopedics and
        Trauma-Surgery. All patients ≤ 18 years who suffered a traumatic injury or vascular surgery
        due to a planned orthopedic extremity tumor resection were included in this study. 33
        patients underwent vascular repair, a total of 15 patients fulfilling the criteria could be
        identified.
Pressure Ulcers in Knee Replacement Surgery
Condition: Knee Osteoarthritis; Pressure Ulcer
MeSH terms: Pressure Ulcer
Study type: Observational

Summary: 
      From the point of view of nursing to know exactly the different risk factors for the onset of
      pressure ulcers is very important as it allows to accurately orient preventive care
      interventions.

      All the variable that could influence the development of pressure ulcer in patients
      undergoing knee replacement surgery are identified and collected: age, sex, body max index,
      risk to develop Pressure Ulcer (braden score), treatment to prevent pressure ulcers (typology
      of the devices used, such as air mattresses with alternating or static pressure, heel drains,
      frequency of mobilization carried out by both the patient care), management of eventual
      incontinence (use of diapers, urinary catheter), type of anesthesia, type of analgesia,
      length of stay, the ASA physical status classification system (ASA score), comorbidity,
      cancer, use of devices for controlling the position of the operated limb (foam valve), the
      number of physical therapy sessions actually carried out.
    


Observational model: Cohort
Time perspective: Retrospective
Sampling method: Non-Probability Sample
Study population: 
        Patients undergoing knee replacement surgery following chronic joint disease
Acute Effect of Massage and Exercise on Muscle Tenderness
Condition: Musculoskeletal Disorders
MeSH terms: Musculoskeletal Diseases
Study type: Interventional

Summary: 
      Many people experience pain, tenderness and soreness of joint and muscles, both in sport and
      working life. Pain killers can provide acute relief of pain, but may not be a feasible
      solution for all people. Here the investigators examine the acute effect of massage and
      exercise on induced muscle tenderness (delayed onset muscular soreness).
    


Intervention name(s): Exercise; Massage
Intervention type(s): Behavioral; Other
Intervention description(s): Exercise will be performed for 10 minutes at the left or right trapezius (randomized); massage will be provided for 10 minutes at the left or right trapezius (randomized)
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Prevention
Keywords: DOMS
To Examine Smoking Behavior of Prisoners - 1
Condition: Smoking Behavior
Study type: Observational

Summary: 
      The purpose of this study is to understand the smoking behavior of female incarcerated
      smokers and to determine how smokers differ from non-smokers on measures of substance abuse,
      personality, criminal history, and mental illness
    


Observational model: Cohort
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        All adult women incarcerated in a state prison in Virginia are eligible to participate.
Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation Among Patients Undergoing Magnetic Resonance Imaging in Radiology Department at ILBS, New Delhi.
Condition: Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation Among Patients Undergoing Magnetic Resonance Imaging
MeSH terms: Anxiety Disorders
Study type: Interventional

Summary: 
      A study to assess the Effectiveness of Video Based Education Versus Music Therapy on Anxiety,
      Experience, and Co-operation among Patients undergoing Magnetic Resonance Imaging. This is a
      Experimental Multiple Interventions Pre test - Post test Design. Three groups namely, Video
      Based Education group, Music Therapy Group and control groups are there in study.There will
      be significant difference in the Mean Anxiety Scores, Experience level, and Co-operation
      level of patients undergoing MRI in Video Based Education , Music Therapy group and Control
      Group
    


Intervention name(s): Video Based Education, Music Therapy
Intervention type(s): Behavioral
Intervention description(s): Video Based Education and Music Therapy was given as a part of Interventions to relieve anxiety of patients undergoing Magnetic Resonance Imaging
Other intervention name(s): VBE, MT
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Participants were assigned randomly to three groups
Masking: Double (Participant, Care Provider)
Primary purpose: Supportive Care
Keywords: Anxiety, Video Based Education, Music Therapy, Experience, Cooperation, Magnetic Resonance Imaging
The Effects of Acupuncture on Insomnia Among Midlife Women
Condition: Menopause Syndrome
MeSH terms: Sleep Initiation and Maintenance Disorders
Study type: Interventional

Summary: 
      Aims: To explore the effects of acupuncture on the improvement of insomnia, fatigue,
      depression and menopausal symptoms among midlife women.
    

Detailed description: 
      This research is a study with a randomized clinical trial. Participants were 40-60 years old
      with a sleep disturbance which persists more than one month. Twenty participants were
      randomly assigned into the experimental and control groups. The experimental group received
      acupuncture treatment (Taichong, Shenmen, Neiguan points) twice a week, total three weeks,
      plus sleep hygiene guidance; the control group received subcutaneous acupuncture
      (non-therapeutic acupuncture points) twice a week, total three weeks and given sleep Health
      guidance. All participants received pre-test and post-test, including sleep multiple
      physiological examination (PSG), Pittsburgh sleep quality table, Epworth sleepiness scale,
      hospital anxiety depression scale, menopausal symptom questionnaire, sleep disturbance
      comprehensive scale, and wore Actiwatch for three days. Data analysis was performed using
      SPSS.
    

Intervention name(s): Acupuncture
Intervention type(s): Other
Intervention description(s): Acupoint:Taichong, Shenmen, Neiguan points with twice a week for total three weeks
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: This study is designed according to the Impaired Sleep Model, and is a single-blind randomized clinical trial.
Masking: Single (Participant)
Primary purpose: Treatment
Keywords: Midlife Women; Acupuncture; Insomnia; Polysomnography