Pulsed Electromagnetic Field Versus Pulsed High Intensity Laser in the of Osteoprosis
Condition: Osteopenia or Osteoporosis
MeSH terms: Osteoporosis; Bone Diseases, Metabolic
Study type: Interventional

Summary: 
      Osteoporosis is the most prevalent metabolic bone disease. Although osteoporosis is widely
      considered to be much more prevalent in women approximately 39% of new osteoporotic fractures
      estimated to have occurred Worldwide in 2000 were in men. A number of studies investigate the
      effect of physical therapy modalities in treatment of osteoporosis. The use of pulsed
      electromagnetic field (PEMF) represents an attractive alternative for Osteoporosis. Previous
      studies suggested that pulsed electromagnetic field could be beneficial for increase bone
      mineral density in osteoporotic patients, but there is a lack of Knowledge about the
      comparison with pulsed high laser therapy.
    

Detailed description: 
      Objectives: This randomized controlled study aims to investigate theEffect of Full-Body
      Pulsed Electromagnetic Field versus Pulsed High Intensity Laser Therapy in the Treatment of
      Men with Osteopenia or Osteoporosis Methods: Ninty male patients with osteopenia or
      osteoporosis will participate in this study, their age ranges between 30-60 years. They have
      BMD T-scores ≤ - 1.5. All patients will be randomized into one of three groups. Group one
      received PEMF and exercise (PEMF+EX), group two received HILT and exercise (HILT+EX) and
      group three will be treated by exercise alone (Ex). The exercise training program will
      include treadmill and aerobic exercises for hip and upper limb will be performed for 50
      minutes.PEMF was administered to the whole body for PEMF groups using a 1.8×0.6m mat 30
      minutes/day, 3 times/week for 3 months. Dual-energy X-ray absorptiometry (DEXA) will assess
      Bone mineral density BMD (g/cm2), bone mineral content (BMC), T-Score and Z-Score at the
      lumbar spine, proximal femur and forearm region, bone markers (25-hydroxy Vit D , Total,
      undercarboxylated Ostocalcin, Parathyroid Hormone, Total and Ionized calcium and Alkaline
      Phosphatase (ALP), also will be measured. The assessment will be done at baseline, after
      treatment (12 weeks) and after 6 months as follow up. The data will be analyzed using
      repeated measures Analysis of variance (ANOVA) for comparison between pre-treatment and post
      treatment measurement intervals. One-way ANOVA is used to compare between each treatment
      interval in treatment groups at pre-test and post treatment measurement intervals. The level
      of significance is set at 0.05 for all tests.
    

Intervention name(s): Pulsed Electromagnetic Field; Exercise Program; Pulsed High Laser Therapy
Intervention type(s): Other; Other; Other
Intervention description(s): PEMF was administered to the whole body for PEMF groups using a 1.8×0.6m mat 30 minutes/day, 3 times/week for 3 months.; The exercise training program included treadmill and aerobic exercises for hip and upper limb and performed for 50 minutes.; High Laser was delivered with a total dose of energy of 3000 J was delivered in two treatment phases. The initial phase was performed with fast manual scanning at 510, 610, and 710 mJ/cm2 in three successive subphases and 500 J in each subphase for a total of 1500 J. The final phase was the same as the initial phase except that the scanning was slow. The average area for the upper thigh or lower back was 200 cm2 with an average fluency of 15 J/cm2 and the application time for each area was 18 min. HILT was applied using a HIRO 3 device (ASA, Arcugnano, Vicenza, Italy).
Allocation: Randomized
Intervention model: Factorial Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary purpose: Treatment
Keywords: T-scores of ≤1.5