The Effect of Peripheral Neuropathy Symptoms on Temporomandibular Joint Functionality
Condition: Diabete Type 2
MeSH terms: Peripheral Nervous System Diseases; Diabetes Mellitus, Type 2
Study type: Observational

Summary: 
      The aim of this observational case-control study was to investigate the effect of diabetic
      peripheral neuropathy symptoms on temporomandibular joint functionality in patients with type
      2 diabetes.
    

Detailed description: 
      The number of participants planned to be included in the study was decided with the G-Power
      programme. While calculating the number of individuals to be included in the study, it was
      calculated that the sample size to obtain an effect size of 0.6 for the purpose of evaluation
      within the 95% confidence interval in a way to provide 80% study power at 5% Type 1 and 20%
      Type 2 error limits should be 74 (n=37) individuals. This study included 70 individuals (DM
      study group=40 individuals, control group=30 individuals).

      Peripheral neuropathy symptoms of all participants were evaluated with the Michigan
      Neuropathy Screening Test. In the evaluation of TMJ functionality, the presence of pain,
      maximum pain-free mouth opening, mandibular dysfunction and dysfunction were assessed with
      the help of scales. Duration of diabetes mellitus was recorded and quality of life was
      evaluated with Ferran Powers Quality of Life Index.
    

Intervention name(s): Michigan Neuropathy Screening Instrument; Numeric Pain Scale; Mandibular Function Disorder Questionnaire; Fonseca Anamnestic Index; Ferrans&Powers Quality of Life Index Diabetes Version
Intervention type(s): Other; Other; Other; Other; Other
Intervention description(s): A two-step test consisting of symptom questionnaire and physical examination was used. The symptom questionnaire includes 15 questions about the legs and feet. Physical examination includes assessment of the appearance of the feet, Achilles reflex, thumb vibration and monofilament tests.; In this simple method, which is frequently used to measure pain intensity in the clinic and whose validity and reliability have been demonstrated, the participant is asked to mark a number on a 10 cm scale with numbers ranging from "0" (no pain) to "10" (unbearable pain) for the pain.; This valid and reliable scale evaluating mandibular dysfunction consists of two dimensions and 17 questions.A high total score obtained from the questionnaire indicates a high level of impairment in jaw function; This scale, which is valid and reliable as a TMJ disorder assessment tool, includes 10 questions. The presence of TMD is accepted in those with a score of 25.; This index consists of two parts and a total of 68 items. A high score indicates a good quality of life.
Observational model: Case-Control
Time perspective: Cross-Sectional
Sampling method: Probability Sample
Study population: 
        The study group included individuals aged between 48-78 (min-max) years who were diagnosed
        with type 2 DM in the treatment units of Harran University Training and Research Hospital,
        while the control group included age and gender homogeneous healthy individuals without a
        diagnosis of DM.
      
Keywords: diabetes mellitus; temporomandibular joint; neuropathy