Are There Dietary Factors Affecting the Development of Pancreatitis in Patients With Gallstones?
Condition: Diet Habit; Gall Stone; Pancreatitis
MeSH terms: Pancreatitis; Gallstones
Study type: Observational [Patient Registry]

Summary: 
      The most common cause of acute pancreatitis is gallstones. It is known that diet and obesity
      play a role in the formation of gallstones. It has been reported that the risk of gallstone
      formation is two times higher in obese individuals with a body mass index (BMI) >30 than in
      normal-weight individuals with a BMI between 20-25. The epidemiological literature on the
      relationship between diet and risk of acute pancreatitis is very limited. In addition, it is
      often unclear which type (acute, recurrent, or chronic) and subtype (gallstone-related or
      non-gallstone-related) of acute pancreatitis is studied in studies. Although there are
      studies in the literature evaluating the relationship between diet and development of
      gallstones or the development of pancreatitis with diet, studies examining the role of diet
      in the development of pancreatitis in patients with gallstones are very limited. In this
      study, we aimed to investigate the dietary differences in patients with gallstones who had
      pancreatitis and those who did not.
    

Detailed description: 
      The incidence of acute pancreatitis has been reported as 4.9-35/100.000, and the incidence
      increases every year with the increase in obesity and gallstone rates. It is most commonly
      observed between the ages of 30-60 and no difference was found in terms of gender
      distribution. The most common cause of acute pancreatitis is gallstones. Alcohol use, drugs
      and other reasons come next.

      It is known that diet and obesity play a role in the formation of gallstones. It has been
      reported that the risk of gallstone formation is two times higher in obese individuals with a
      body mass index (BMI) >30 than in normal-weight individuals with a BMI between 20-25. In
      addition, many studies have reported that increased use of dietary refined carbohydrates and
      triglycerides and reduced dietary fiber intake are associated with gallstone formation.

      The epidemiological literature on the relationship between diet and risk of acute
      pancreatitis is very limited. In addition, it is often unclear which type (acute, recurrent,
      or chronic) and subtype (gallstone-related or non-gallstone-related) of acute pancreatitis is
      studied in studies. On the other hand, Sarles et al. In a comprehensive study conducted in
      1973, he reported that high fat and protein consumption and alcoholism increase the risk of
      pancreatitis, regardless of etiology. Few case-control and ecological studies have evaluated
      the effect of protein, fat, and carbohydrate intakes on alcohol-related or gallstone-related
      acute pancreatitis risk or non-gallstone-related acute pancreatitis risk or acute
      pancreatitis mortality.

      At the beginning of the twentieth century, an inverse relationship between coffee consumption
      and the risk of alcohol-induced acute pancreatitis was observed in a prospective study, and
      an inverse relationship with fruit consumption in two smaller case-control studies, and a
      positive association with consumption of freshwater fish and parboiled rice. In parallel,
      overly large meals and food allergies after a long period of fasting have been reported to be
      risk factors for acute pancreatitis.

      Although there are studies in the literature evaluating the relationship between diet and
      development of gallstones or the development of pancreatitis with diet, studies examining the
      role of diet in the development of pancreatitis in patients with gallstones are very limited.
      In this study, we aimed to investigate the dietary differences in patients with gallstones
      who had pancreatitis and those who did not.

      In the study, age, gender, body mass index, alcohol and cigarette consumption status, daily
      physical activity status, eating frequency, frequency of food consumption for three days, and
      their food consumption status will be evaluated with the BeBis 8 Full version program and it
      will be compared whether there is a difference between patients who had pancreatitis and
      those who did not. .
    

Intervention name(s): diet survey
Intervention type(s): Other
Intervention description(s): Dietary survey applied to all participants
Observational model: Case-Control
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        All the participants have gallstone. In control group participants did not have any
        pancreatitis history. In case group patients have pancreatitis.
      
Keywords: meat; egg; fat; protein