The Bed Rest Avoidance Study
Condition: Study Focuses on Bed Rest and Deconditioning in Hospital Inpatients
Study type: Interventional
Phase: Phase 3

Summary: 
      Hospitalized patients spend the majority of their time lying in bed, even when they are
      capable of being out of bed. Up to 50% of inpatients suffer functional decline at least in
      part due to lying in bed after admission, and even those who are not placed on bed rest by
      their physicians spend an average of 20 out of 24 hours lying in bed. The loss of functional
      ability and exercise tolerance happens remarkably fast, as early as hospital day 2 (24-48
      hours). Functional decline often results in a prolonged hospital stay and the need for
      additional rehabilitation resources both during and after the hospitalization to return a
      patient to their baseline functional status. Functional decline has also been associated with
      excess mortality.

      The investigators sought to flip the culture of hospital-based care such that the bed was
      viewed as a place for patients to sleep, and patients would be encouraged to get out of bed
      when they were not trying to sleep. The investigators hypothesized that patients were unaware
      of the risks of prolonged immobilization and that the lack of an alternative comfortable
      place for patients to sit other than their bed contributed to their immobility. Previous
      studies have demonstrated that mobility protocols improve patient-centered outcomes in narrow
      patient populations such as post-surgical patients or the elderly, but such interventions
      have not been studied in a heterogeneous patient population. Additionally, previously studied
      protocols have been labor-intensive from a nursing standpoint, requiring, for example, that
      staff provide one-on-one supervised ambulation 3-4 times per day. The investigators aimed to
      determine whether establishing a relatively low-intensity, pragmatic protocol to discourage
      patients from lying in bed would result in shorter length of stay by improving mobility. The
      investigators further aimed to assess the additional impact of providing a recliner chair, a
      safe and comfortable alternative to their bed on these outcomes.

      This a prospective, controlled investigation of a novel intervention intended to reduce time
      subjects spent lying in bed. The intervention will be conducted at Los Angeles County +
      University of Southern California (LAC+USC) Medical Center from March 20, 2017 through
      September 19, 2017. The intervention and control wards are symmetrically laid out. All wards
      consist of medical/surgical beds without cardiac telemetry monitoring. Subjects will be
      admitted per clinical routine, with bed assignments made by the bed control department, which
      was not aware of the study. Handouts developed at a 3rd grade level will inform subjects and
      their families about the risks of bed rest and encouraged the subjects to only lie in bed
      when they were attempting to sleep. Handouts are translated into 5 languages (Spanish,
      Korean, Tagalog, Mandarin, Vietnamese). Nursing staff on the intervention wards will provide
      these handouts to subjects and their families as part of the standard admission process. In
      addition, laminated reminder signs identical to the handouts will be posted on the wall
      opposite the head of the bed. Posters were placed in the main entrance of the study units.

      Half of the intervention rooms will also be provided with recliner chairs (Winco Vero Care
      Cliner) that were bariatrics rated to 500 pounds, vinyl-covered for facile disinfection, and
      had 180-degree swing arms and locking casters. The other intervention rooms and the control
      rooms had standard hospital chairs in addition to the hospital bed.

      The primary outcome measure is the difference in the length of hospital stay for admissions
      to intervention rooms compared to control rooms. Subjects' age and gender will be collected
      in order to control for these factors in the primary analysis. The Medicare Severity
      Diagnosis Related Group (MS DRG) relative weight for each patient will be collected to
      control for illness severity.

      As a secondary endpoint, functional status will be assessed using the "6-Clicks" objective
      functional scoring system. Scores will be measured at several points during the each
      hospitalization As a process measure, nurses will maintain a log of hours per shift that
      subjects spend in bed. Finally, as a safety measure, the rates of falls per 1000 patient-days
      will be collected.

      Data will be abstracted using an automated query of the electronic health record's bed
      management database (Cerner, Kansas City, MO). All patients who are placed on one of the
      study wards during the intervention period-including those admitted from the emergency
      department, elective medical and surgical admissions, inter-hospital transfers and
      intra-hospital transfers-will be included.
    


Intervention name(s): Provision of recliner chairs and encouragement to get out of bed
Intervention type(s): Behavioral
Intervention description(s): Provision of recliner chairs and encouragement to get out of bed
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Prevention