Comparative Study on Postoperative Analgesia With Transversus Abdominis Plane Block to Local Anesthetic Infiltration With Ropivacaine in Laparoscopic Abdominal Surgery
Condition: Analgesia; Ropivacaine; Laparoscopic Abdominal Surgery; Local Infiltration
MeSH terms: Agnosia
Study type: Interventional

Summary: 
      The goal of this clinical trial is to compare the postoperative analgesic efficacy of
      ultrasound-guided TAP block with Local Anesthetic Infiltration of ropivacaine in patients
      undergoing laparoscopic surgery. The main question it aims to answer is:

      • If Transversus Abdominis Plane block with Ropivacaine will produce long duration of
      analgesia than the Local Anesthetic Infiltration with ropivacaine after laparoscopic
      abdominal surgery .
    

Detailed description: 
      Pain is a natural phenomenon. Pain is an unpleasant sensory and emotional experience
      associated with actual or potential tissue damage. Pain is distressing and detrimental in
      post-operative patients. Management of post-operative pain has been a challenge to
      anesthetists. Pain treatment increase speed of recovery, minimum patient suffering, decrease
      length of stay, reduced hospital costs, increased patient satisfaction, increase productivity
      and quality of life.

      Peripheral nerve blockade or field block with local anesthesia is helpful in managing
      postoperative pain effectively whilst avoiding complication associated with intravenous
      narcotics or neuraxial blockade. Regional block will help in reduction of dose and frequency
      of intravenous narcotics used in postoperative period, hence minimizing the side effects of
      narcotics.

      Ultrasound guided abdominal nerve blocks are increasingly being used for anaesthesia and
      analgesia. The Transversus Abdominis Plane (TAP) block is a peripheral nerve block that
      results in anesthesia of the abdominal wall. This plane represents an anatomical potential
      space with nerves leaving the plane to innervate the abdominal muscles and skin. Transversus
      abdominis plane block (TAP block) is a novel procedure to provide postoperative analgesia
      following laparoscopic surgery.

      Ropivacaine has a greater degree of motor sensory differentiation. Ropivacaine has been
      safely used up to the dose of 200 mg (100 ml of 0.2% ropivacaine) as a field block for post
      operative analgesia. We are giving a larger volume of ropivacaine (20 ml on each side)
      expecting to cover the upper abdomen when TAP block is performed via posterior approach.

      NULL HYPOTHESIS There is no difference in post operative analgesia with Transversus Abdominis
      Plane block and local anesthetic infiltration after laparoscopicabdominal surgery

      General objective

      1. To compare the efficacy of Transversus Abdominal plane block and local anesthetic
      infiltration after laparoscopic abdominal surgery

      Specific objective

        1. To compare the visual analog score (VAS) between two groups

        2. To compare time to first analgesic requirement between two groups.

        3. To compare the total dose of analgesia in 24 hours between the two groups
    

Intervention name(s): Ropivacaine in Transversus abdominis plane; Ropivacaine in Local infiltration at port site
Intervention type(s): Drug; Drug
Intervention description(s): This group received 20ml of Ropivacaine 0.2% Injectable Solution in bilateral transversus abdominis plane at the end of surgery; This group received local infiltration of 20ml of Ropivacaine 0.2% Injectable Solutionat port sites at the end of surgery
Intervention MeSH terms: Ropivacaine
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Patients were randomly assigned to two groups having 50patients in each, by using a computer-generated table of random numbers which was enclosed in a sealed envelope and was opened by an anesthesia assistant who was not involved in the study.
Masking: Double (Participant, Care Provider)
Primary purpose: Supportive Care
Keywords: Ropivacaine; TAP Block; Analgesia; Laparoscopic abdominal surgery