Cardiometabolic Effects of Aerobic Exercise Plus Breaking Sitting
Condition: Sedentary Behaviour; Sedentary Time
Study type: Interventional

Summary: 
      The goal of this randomized crossover clinical trial is to investigate the effects of
      interrupting prolonged sitting with intermittent walks of equal volume but at different
      frequencies, in addition to moderate-intensity aerobic exercise, on postprandial serum lipid
      profile in young adults between the ages of 18-30. The main questions it aims to answer are:

        -  Do interrupting prolonged sitting with intermittent walks of equal volume but at
           different frequencies sustain positive cardiometabolic effects after moderate-intensity
           aerobic exercise?

        -  If "yes", which frequency of breaks is more effective to provide cardiometabolic
           benefits?

      Participants will complete four conditions on separate days: 1) 6.5 hours of prolonged
      sitting after 30 minutes of moderate intensity aerobic exercise 2) breaking prolonged sitting
      with 2 minutes of walking every 30 minutes after 30 minutes of moderate intensity exercise 3)
      breaking prolonged sitting with 4 minutes of walking every 1-h after 30 minutes of moderate
      intensity exercise 4) breaking prolonged sitting with 8 minutes of walking every 2-h after 30
      minutes of moderate intensity aerobic exercise.
    


Intervention name(s): Aerobic exercise+6.5 h of prolonged sitting; Aerobic exercise+2 minutes of walking breaks every 30 minutes; Aerobic exercise+4 minutes of walking breaks every 1-h; Aerobic exercise+8 minutes of walking breaks every 2-h
Intervention type(s): Other; Other; Other; Other
Intervention description(s): Volunteers, whose fasting blood samples are drawn and who eat a standard breakfast, will perform a 30-minute walking exercise on a treadmill at 40-45% of their heart rate reserve. They will then sit in the chair for 6.5 hours. While seated, volunteers will be asked not to leave their seats except to use the toilet. Volunteers will be able to read and use computers and phones while sitting. Venous and capillary blood samples will be drawn at regular intervals and their blood pressures will be measured.; Volunteers, whose fasting blood samples are drawn and who eat a standard breakfast, will perform a 30-minute walking exercise on a treadmill at 40-45% of their heart rate reserve. They will then interrupt sitting with 2-minute walks at 35-40% of their heart rate reserve every 30 minutes for 6.5 hours after moderate-intensity aerobic exercise. They will make a twelve interruptions throughout 6.5 hours period and will have a total of 24 minutes of interruption throughout the intervention. While seated, volunteers will be asked not to leave their seats except to use the toilet. Volunteers will be able to read and use computers and phones while sitting. Venous and capillary blood samples will be drawn at regular intervals and their blood pressures will be measured.; Volunteers, whose fasting blood samples are drawn and who eat a standard breakfast, will perform a 30-minute walking exercise on a treadmill at 40-45% of their heart rate reserve. They will then interrupt sitting with 4-minute walks at 35-40% of their heart rate reserve every 1 hour for 6.5 hours after moderate-intensity aerobic exercise. They will make six interruptions throughout 6.5 hours period and will have a total of 24 minutes of interruption throughout the intervention. While seated, volunteers will be asked not to leave their seats except to use the toilet. Volunteers will be able to read and use computers and phones while sitting. Venous and capillary blood samples will be drawn at regular intervals and their blood pressures will be measured.; Volunteers, whose fasting blood samples are drawn and who eat a standard breakfast, will perform a 30-minute walking exercise on a treadmill at 40-45% of their heart rate reserve. They will then interrupt sitting with 8-minute walks at 35-40% of their heart rate reserve every 2 hour for 6.5 hours after moderate-intensity aerobic exercise. They will make six interruptions throughout 6.5 hours period and will have a total of 24 minutes of interruption throughout the intervention. While seated, volunteers will be asked not to leave their seats except to use the toilet. Volunteers will be able to read and use computers and phones while sitting. Venous and capillary blood samples will be drawn at regular intervals and their blood pressures will be measured.
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Other
Keywords: sedentary break; prolonged sitting; blood lipids; blood pressure; aerobic exercise; walking