The Effect of Proprietary Water on Physiological and Perceptual Responses
Condition: Hydration; Dehydration
MeSH terms: Dehydration
Study type: Interventional

Summary: 
      The purpose of this study is to determine if drinking proprietary water (PW) during a
      standardized daily plan as compared to distilled water (control) and carbohydrate-electrolyte
      (CE) drink can improve hydration status over time. Another purpose is to determine if PW, as
      compared to control and CE, can improve hydration status, perceptual responses, physiological
      responses, and cognition measures in a heat stressful environment. Healthy, physically active
      males and females aged 18 to 50y will be recruited for the study. Participants will be
      randomized into one of three groups: PW, CE, or Control. The participant will be given a
      daily standardized plan integrating their assigned fluid into daily hydration habits for five
      days. Participants will provide their first-morning urine sample, keep a daily food log, and
      answer questions about their perceptions of hydration. After the five days, they will
      participate in a treadmill exercise protocol within a warm environment (heat chamber).
      Multiple physiological, perceptual, and cognitive measures will be obtained while
      participants exercise and then recover.
    

Detailed description: 
      The study will investigate the effects of drinking proprietary water over a five-day
      free-living period and then during a heat stress environment compared to distilled water and
      a carbohydrate-electrolyte drink on markers of hydration, performance, and cognition. This
      will be a single-blind between-subjects study design. Participants will report to The
      University of South Carolina for two visits. At the first visit, potential participants will
      be explained the procedures and risks of the study and then sign an informed consent.
      Anthropometrics and demographic data will next be collected. Lastly, participants will be
      familiarized with specific measures and the testing protocol. Participants will take home
      study products to consume over 5-free living days in which they will need to keep a food and
      drink log and collect their first urine void of the day to drop off at the laboratory. After
      the free-living days, participants will return to the laboratory for their heat stress
      environment test. They will consume a standardized breakfast, complete questionnaires, then
      perform a 45-minute exercise protocol in the heat chamber. After the first 45-minutes, there
      will be a break to complete cognitive measures and return to the heat chamber for another
      45-minute exercise protocol. Throughout the exercise protocols, participants will be
      responding to perceptual questions and blood draws. Following, they will rest for 60 minutes,
      during which they will answer more perceptual questionnaires and blood measures.
    

Intervention name(s): proprietary water; Active comparator; Placebo
Intervention type(s): Dietary Supplement; Other; Other
Intervention description(s): They are randomized to consume a proprietary water product for five-free living days and to drink on the heat stress chamber day.; They are randomized to consume a carbohydrate drink for five-free living days and to drink on the heat stress chamber day.; They are randomized to consume water for five-free living days and to drink on the heat stress chamber day.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Between subjects, single-blind
Masking: Single (Participant)
Primary purpose: Other