Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth
Condition: Obesity and Type 2 Diabetes
MeSH terms: Diabetes Mellitus; Diabetes Mellitus, Type 2
Study type: Interventional

Summary: 
      The overall goal of this project is to examine the physiological and metabolic effects of a
      16-week circuit-training (strength training + aerobic activities) program, with and without a
      behavioral component utilizing motivational interviewing, in 45 overweight Latina adolescent
      girls (14-18 years of age). This 16-week randomized control study will examine the
      incremental effects of the following 3 intervention groups on insulin sensitivity, insulin
      secretion, adiposity, and habitual and ad libitum physical activity:

        -  Control group (delayed circuit training intervention; n=15)

        -  Circuit training group (strength + aerobic training; 2 times per week; n=15)

        -  Circuit training (same as above) + weekly motivational interviewing sessions (n=15)

      Specific Aim 1: To examine the effects of a 16-week circuit training program on adiposity,
      insulin dynamics, other associated hormones and adipocytokines, cardiorespiratory fitness,
      and muscular strength in overweight Latina adolescent girls. Hypothesis 1: Participation in
      the circuit-training program will result in significant improvements in both physiological
      and metabolic outcomes, including: a) body composition as measured by DEXA, b) fat
      distribution as measured by MRI, c) adipose tissue hormones (e.g. leptin, adiponectin, TNF-α)
      as measured by fasting blood samples, d) insulin sensitivity and secretion as measured by
      frequently sampled intravenous tolerance test, e) aerobic fitness as measured by the single
      stage submaximal treadmill test, and f) increase muscular strength as measured by repetition
      maximums.

      Specific Aim 2: To examine the incremental effects of adding the motivational interviewing
      sessions to the circuit training on self-selected ad libitum physical activity during a
      5-hour observational period, habitual physical activity levels using 7 day accelerometry, and
      the meanings and motivation to exercise using questionnaires before and after the
      intervention. Hypothesis 2: The addition of motivational interviewing will encourage and
      empower participants to be more active outside of the intervention and foster healthy
      physical activity behaviors in daily life. Improvements in physical activity behaviors will
      lead to greater improvements in all other health outcomes listed in specific aim 1 compared
      to circuit training alone and control group.
    


Intervention name(s): Circuit Training; Circuit training + motivational interviewing
Intervention type(s): Behavioral; Behavioral
Intervention description(s): Circuit Training (aerobic + strength training 2 times per week for 16 weeks); Circuit training (aerobic + strength training 2 times per week for 16 weeks) + motivational interviewing (4 individual + 4 group sessions)
Other intervention name(s): CT; CT + MI
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Prevention
Keywords: obesity; adolescents; adiposity; insulin sensitivity; type 2 diabetes; Latino; circuit training; physical activity; motivational interviewing