The Effect of Bilateral Erector Spina Plane Block on Postoperative Analgesia in Cesarean Section Under SpinalAnaesthesia
Condition: Pain, Postoperative
MeSH terms: Pain, Postoperative
Study type: Interventional

Summary: 
      Acute pain after cesarean section (SC) can be variable. Untreated pain can affect patients'
      life quality. Currently regional nerve blocks are frequently used as a part of multimodal
      analgesia. Erector spina plane block (ESPB), a recently defined interfacial plane block,
      provides multisegmental analgesia by spreading to both ventral and dorsal branches of the
      spinal nerve roots in the cranio-caudal plane with a single injection. The aim of this study
      is to evaluate the effects of ESPB on postoperative pain, analgesic use and patient
      satisfaction in patients delivered by CS under spinal anesthesia.
    

Detailed description: 
      Cesarean section (CS) is one of the most common surgical procedures in the world. Acute pain
      intensity after cesarean section can be variable, making difficult to predict pain severity.
      Untreated pain can affect patients' life quality. Currently regional nerve blocks are
      frequently used as a part of multimodal analgesia. Erector spina plane block (ESPB) is a
      recently defined interfascial plane block. As a result of ultrasound (USG) guided local
      anesthetic drug injection into the fascial plane between erector spina muscle and vertebral
      transverse process, multisegmental analgesia provided by spreading to the both ventral and
      dorsal branches of the spinal nerve roots in cranio-caudal plane with a single injection. The
      primary aim of this study was to evaluate the effects of bilateral ESPB on postoperative
      pain, using the visual analog scale (VAS) in patients delivered by CS under spinal
      anesthesia. The secondary aims of the study are to evaluate the effects of ESPB on analgesic
      drug use and patient satisfaction in the postoperative period.

      116 pregnants, aged between 18-45 years, delivered by CS from May 2020 to June 2021 included
      the prospective, randomised, single centre study. Exclusion criteria were age under 18 years,
      over 45 years, body mass index (BMI) over 35 kg/m2, ASA status over III, multiple pregnancy,
      preeclampsia, bleeding diathesis, opioid use and allergy to drugs to be used in the study.
      Spinal anesthesia was administered with 0.5% bupivacaine and fentanyl 12.5mcg at the level of
      L4-5 interspace with 26G quincke spinal needle in the sitting position. At the end of the
      surgery, in ESPB group, patients were given a sitting position with the help of 2 people for
      USG-guided ESPB. The high-frequency linear USG probe was placed in the midline at T12 level,
      after the spinous process visualized, the transverse process was visualized by moving probe
      3-4cm laterally. After confirming the location of the needle tip with 1-2ml hydrodissection,
      10 ml bupivacaine + 10 ml salin was applied both right and left sides. At the postoperative
      2, 4, 6, 12 and 24th hours, patients' rest, cough, movement, low back and headache VAS
      values, analgesic drug use, first analgesic use time and satisfaction were evaluated. ESPB
      spread level was evaluated with pin-prick at the 4-6th hours. The SPSS 11.5 program was used
      for statistical analysis.
    

Intervention name(s): Spinal anesthesia + bilateral erector spine plane block; Spinal anesthesia
Intervention type(s): Other; Other
Intervention description(s): Intraoperative period: Spinal anesthesia was administered with 0.5% bupivacaine and fentanyl 12.5mcg at the level of L4-5 interspace in the sitting position. At the end of the surgery, patients were given a sitting position with the help of 2 people for USG-guided ESPB. The high-frequency linear USG probe was placed in the midline at T12 level, after the spinous process visualized, the transverse process was visualized by moving probe 3-4cm laterally. After confirming the location of the needle tip with 1-2ml hydrodissection, 10 ml bupivacaine + 10 ml salin was applied both right and left sides.
Postoperative period: If patients' VAS value >4, 75mg diclofenac intramuscular was administered. After 30 mins if patients' VAS values >4, 1000mg paracetamol intravenously was administered.; Intraoperative period: Spinal anesthesia was administered with 0.5% bupivacaine and fentanyl 12.5mcg at the level of L4-5 interspace in the sitting position.
Postoperative period: If patients' VAS value >4, 75mg diclofenac intramuscular was administered. After 30 mins if patients' VAS values >4, 1000mg paracetamol intravenously was administered.
Intervention MeSH terms: Anesthetics
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Supportive Care
Keywords: Erector spina plane block; postoperative pain; obstetric analgesia