The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males
Condition: Mental Fatigue
MeSH terms: Mental Fatigue
Study type: Interventional

Summary: 
      This is a cross-over design study in which subjects arrived to the lab and were assigned a
      supplement to ingest. Prior to ingestion subjects completed baseline reaction time testing
      along with a questionnaire. Thirty minutes after ingestion subjects filled out the same
      questionnaire, completed a reaction time test, followed by a series of dynamic exercises.
      After the last exercise was finished subjects filled out the questionnaire, completed another
      reaction time test and repeated the series of dynamic exercises. Following the exercises,
      subjects filled out the questionnaire and completed a fourth round of reaction time testing.
      In total subjects would complete 2 rounds of dynamic exercises and 4 rounds of reaction time
      testing with heart rate being recorded before and after the dynamic exercise rounds. Subjects
      were told to wash-out for 7 days and return to the lab to complete the same testing but on
      the alternative supplement.
    

Detailed description: 
      Subjects expressing interest in doing the study, were interviewed in the Human Performance
      Lab (HPL) to determine whether they appear to qualify to participate in the study. Qualifying
      subjects, were then invited back to the HPL for an entry/familiarization session and be
      verbally told all of the requirements of the study. During this session, subjects signed
      Informed Consent Statements and completed personal and medical history questionnaires.
      Subject were familiarized to the study protocol via a verbal and written explanation
      outlining the study design. This included describing the testing sessions to the subjects
      about the tests to be performed including the Makoto testing system (reaction time testing).
      Subjects practiced several times during this session to eliminate the learning curve of using
      new equipment. Subjects were also taken through 1 round of the dynamic exercises to ensure
      ability to complete each exercise as needed. Subjects were then given an appointment time to
      perform qualifying Makoto testing to achieve greater than or equal to 70% accuracy on 3
      towers at a level 7 for three consecutive trails.

      Following the practice session, subjects recorded all food intake via MyFitnessPal for three
      days (3-d) prior to baseline testing. Subjects were instructed to refrain from exercise,
      caffeine, and alcohol the day prior to baseline testing and to consume their normal breakfast
      the morning of testing. Subjects were given a meal replacement bar in place of lunch, to
      consume ~2 hours before their testing session. During this time, subjects had body
      composition and hemodynamic assessments recorded. Two hours after ingestion of meal bar
      subjects reported back to the HPL and completed a Visual Analog Scale (VAS) questionnaire, a
      baseline Makoto prior to ingesting their assigned supplement. Thirty minutes after ingestion,
      Makoto and dynamic exercisers were completed. This involved subjects doing a standardized
      full body workout in 2 different rounds of exercise. After each round of exercise subjects
      filled out the VAS and performed Makoto testing. Subject then were instructed to wash-out and
      were scheduled for their 2nd testing session ~7 days later.
    

Intervention name(s): Caffeine Blend; Sugar Pill
Intervention type(s): Dietary Supplement; Other
Intervention description(s): Taken orally in capsule form; Taken orally in capsule form
Intervention MeSH terms: Caffeine
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Double (Participant, Investigator)
Primary purpose: Other
Keywords: caffeine; mental performance; reaction time; focus