The Effect of Whole Body Vibration in Individuals With Parkinson's Disease
Condition: Parkinson Disease
MeSH terms: Parkinson Disease
Study type: Interventional

Summary: 
      Previous studies reported that whole body vibration has the potential impact on balance and
      walking abilities in individuals with Parkinson's disease; however, the inconsistent
      treatment protocols and different experimental designs lead to inconclusive results.
      Therefore, the purpose of this study is to investigate the short term and long term effect of
      whole body vibration on sensorimotor function in individuals with Parkinson's disease. The
      experimental design will be randomized double-blinded controlled trial. Sixty individuals
      with idiopathic Parkinson's disease will be randomly assigned to two groups and they are
      non-random whole body vibration group and conventional therapy group. Each participant will
      receive the treatment about one hour after the administration of medicine. For non-random
      whole body vibration group, participants will be required to maintain the erect standing
      position on the vibratory platform and the frequency and amplitude of vibratory stimuli will
      be 6Hz and 3mm respectively. Each treatment includes five sessions and each session is
      composed of one minute whole body vibration and one minute rest. For the conventional therapy
      group, participants will receive the occupational therapy including dynamic balance training
      and functional ambulatory training. Each session is 10 minutes in both groups and all
      participants will receive one and twelve treatment sessions for short-term and long-term
      effect respectively. Outcome measures include proprioceptive sensitivity threshold of upper
      limb, position sense test of the knee joint, Unified Parkinson's disease rating scale-motor
      (UPDRS motor), functional reach, and time up and go test (TUG). Specifically, the
      investigators want to answer the following four questions: 1) Is there any difference in
      proprioceptive sensitivity, motor performance and balance before and after treatment in
      individuals with Parkinson's disease? 2) Is there any difference in short-term and long term
      effect of whole body vibration in individuals with Parkinson's disease? 3) Is there any
      difference in treatment effect in individuals with Parkinson's disease in Taiwan?
    


Intervention name(s): non-random whole body vibration; occupational therapy
Intervention type(s): Behavioral; Behavioral
Intervention description(s): Each participant will receive the treatment about one hour after the administration of medicine. For non-random whole body vibration group, participants will be required to maintain the erect standing position on the vibratory platform and the frequency and amplitude of vibratory stimuli will be 6Hz and 3mm respectively. Each treatment includes five sessions and each session is composed of one minute whole body vibration and one minute rest.; Participants will receive the occupational therapy including dynamic balance training and functional ambulatory training.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: randomized double-blinded controlled trial
Masking: Double (Investigator, Outcomes Assessor)
Primary purpose: Treatment
Keywords: proprioception; vibration; balance