Aerobic Versus Resistance Exercises on Liver Enzymes Following Burn Injuries
Condition: Burns
MeSH terms: Burns
Study type: Interventional

Summary: 
      1. Subjects:

           Sixty patients suffering from partial thickness burn with burned body surface area
           (BBSA) about 30% to 50% will be randomly divided into two equal groups each one has 30
           patients.

        2. Equipment and tools:

      2.1. Measurement equipment: Spectrophotometer device. 2.2. Therapeutic equipment and tools:
      Treadmill device for aerobic exercises and dumbbells and sand bags for resistance exercises.
    

Detailed description: 
      Sixty patients who have partial thickness burn with burned body surface area (BBSA) about 30%
      to 50% will participate in this study after their release from intensive care unit. Their
      ages will be ranged from 20 to 45 years. The participants will be selected from Orabi
      hospital and randomly distributed into two equal groups. In this study the patients will be
      randomly assigned into two equal groups (30 patients for each group):

      1.1(a) Group A (Aerobic exercise group): This group includes 30 burned patients who will
      receive aerobic exercises 8 weeks (3times/week) in form of (treadmill device) in addition to
      their physical therapy program (splinting, stretching ex. and ROM ex.) and medical treatment.

      1.1(b) Group B (Resistance exercise group): This group includes 30 burned patients who will
      receive resistance exercises 8 weeks (3times/week) by using dumbbells and sand bags in
      addition to their physical therapy program (splinting, stretching ex. and ROM ex.) and
      medical treatment.

      3.1-Measurement procedures:

        -  Serum blood draws will be taken by certified technicians with the participant in a
           seated position.

        -  Spectrophotometry is the measurable analysis technique using the electromagnetic
           spectra. It deals with the ranges of wavelengths such as near ultraviolet, near infrared
           and visible light. A device called a spectrophotometer is used to measure the absorbance
           or transmittance through a liquid sample. The spectrophotometer takes a measurement at a
           specific wavelength and it is possible to choose any wavelength in the
           spectrophotometers register as the double beam sends a beam through a blank reference
           sample and one through the sample to be measured (Nilsson, 2010).

      3.2-Therapeutic procedures: 3.2.a- Treadmill device for aerobic exercise: During the 8-week
      intervention period, an aerobic training (AT) program of submaximal intensity will include a
      45-minute session three times a week (135 min/week) under the supervision of the researcher.
      Aerobic exercise will consist of three phases: warm-up, training and cool down. At the
      beginning of exercise session, subjects will have a ten-minute warm-up. The warmup protocol
      will be slowly running on treadmill. Then, the warm-up phase will be followed by the training
      phase. At baseline, the training phase will be commenced with two 15-minute running on
      treadmill at 60% of their maximal heart rate (MHR) in the first week and increased to two
      15-minute running on treadmill at 75% MHR per week by the final week of training. By the end
      of exercise session, subjects will have a five-minute cool down. The cool down protocol will
      be slowly running on treadmill (Khalighfard et al., 2011).

      Maximum heart rate will be calculated using the formula: (HRMax =220- age) (Chaudhary et al.,
      2010).

      3.2.b- Dumbbells and sand bags for resistance exercise: Resistance training will be performed
      during 8-weeks with thrice weekly sessions on nonconsecutive days. The program will consist
      of seven exercises: triceps press, biceps curl, lat pull down, calf raise, leg press, leg
      extension and sit-ups using dumbbells and sand bags. Each session will last approximately 45
      minutes and consist of a 5-minute warm-up with stretching following by resistance exercise
      that will be done as a cir¬cuit, ending with 5-minute cool down. The 1 repetition maximum
      (1RM) is measured at baseline and follow¬ing the intervention. Initially, participants will
      do two circuits using 50% of their 1RM and repeat them 10 times for the first and second
      weeks, progressing to two circuits, using 60% of their 1RM and repeat 10 times for the third
      and fourth weeks. In fifth and sixth weeks, participants will do three circuits using 60% of
      their 1RM and repeat 10 times. In the last two weeks, patients will do three circuits using
      70% of their 1RM and repeat 10 times. A 90-second rest will be allowed between sets of
      exercises (Hallsworth et al., 2011).
    

Intervention name(s): Experimental
Intervention type(s): Other
Intervention description(s): The purpose of the study is to evaluate which is more effective aerobic or resistance exercises in reducing plasma liver enzymes level (AST and ALT) post burn. Subjects and Methods: Sixty burned patients with burned body surface area about 30% to 50% will participate in this study. Their ages will be ranged from 20-45 years. They will be selected from Orabi Hospital and will be divided randomly into two equal groups.
Allocation: Randomized
Intervention model: Sequential Assignment
Masking: Single (Participant)
Primary purpose: Treatment