A Castor Bean Solution for Cleaning Dentures
Condition: Prostheses-related Infections
MeSH terms: Prosthesis-Related Infections
Study type: Interventional

Summary: 
      To evaluate the efficacy of a castor bean-based solution (Ricinus communis) for removal of
      complete denture biofilm, comparing it with two products available on the market (sodium
      hypochlorite and alkaline peroxide). Fifty complete maxillary denture-wearers were instructed
      to brush their dentures after meals and once a day, for a period of 07 days, immerse them in
      the following solutions: A - Control: Physiological solution(20 minutes). B - Polident
      alkaline peroxide(3 minutes). C - 1% sodium hypochlorite(20 minutes). D - castor bean-based
      solution(20 minutes). The participants immersed their dentures in each of the solutions,
      according to a randomized sequence. For biofilm quantification, before (Baseline) and after
      the use of each product, the internal surfaces of maxillary complete dentures were revealed
      (1% neutral red), photographed and the stained biofilm was quantified with the aid of
      software (Image Tool 3.0). After concluding measurements of the areas (total and biofilm),
      the percentage of surface covered by biofilm of the complete denture was calculated .
    

Detailed description: 
      The study sought to minimize the occurrence of bias, and whenever possible sought to "blind"
      the parties involved (researchers, volunteers and statisticians), since none of them had
      knowledge of the allocation of treatments. The present study also followed the criteria
      described in the CONSORT Declaration
    

Intervention name(s): Physiological solution; Sodium hypochlorite; Alkaline Peroxide; Castor bean solution
Intervention type(s): Other; Other; Other; Other
Intervention description(s): The volunteers were instructed to brush the internal surface of complete dentures for 2 minutes, 3 times a day, after meals (breakfast, lunch and dinner) and use the following chemical immersion methods, only once a day after dinner: A - Control (Co): Physiological solution, for 20 minutes. B) 1% Sodium Hypochlorite, for 20 minutes. C) Polident Alkaline Peroxide, for 3 minutes. D) 2,0% Castor bean solution Ricinus communis, for 20 minutes. In addition, the participants were instructed to immerse their dentures in water during the night period, before going to sleep.; The volunteers were instructed to brush the internal surface of complete dentures for 2 minutes, 3 times a day, after meals (breakfast, lunch and dinner) and use the following chemical immersion methods, only once a day after dinner: A - Control (Co): Physiological solution, for 20 minutes. B) 1% Sodium Hypochlorite, for 20 minutes. C) Polident Alkaline Peroxide, for 3 minutes. D) 2,0% Castor bean solution Ricinus communis, for 20 minutes. In addition, the participants were instructed to immerse their dentures in water during the night period, before going to sleep.; The volunteers were instructed to brush the internal surface of complete dentures for 2 minutes, 3 times a day, after meals (breakfast, lunch and dinner) and use the following chemical immersion methods, only once a day after dinner: A - Control (Co): Physiological solution, for 20 minutes. B) 1% Sodium Hypochlorite, for 20 minutes. C) Polident Alkaline Peroxide, for 3 minutes. D) 2,0% Castor bean solution Ricinus communis, for 20 minutes. In addition, the participants were instructed to immerse their dentures in water during the night period, before going to sleep.; The volunteers were instructed to brush the internal surface of complete dentures for 2 minutes, 3 times a day, after meals (breakfast, lunch and dinner) and use the following chemical immersion methods, only once a day after dinner: A - Control (Co): Physiological solution, for 20 minutes. B) 1% Sodium Hypochlorite, for 20 minutes. C) Polident Alkaline Peroxide, for 3 minutes. D) 2,0% Castor bean solution Ricinus communis, for 20 minutes. In addition, the participants were instructed to immerse their dentures in water during the night period, before going to sleep.
Other intervention name(s): Saline solution; 1% Sodium hypochlorite; Effervescent tabs; Polident; Ricinus communis solution; Castor oil solution
Intervention MeSH terms: Sodium Hypochlorite; Eusol; Castor Oil; Pharmaceutical Solutions
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary purpose: Prevention
Keywords: biofilm, castor bean, sodium hypochlorite, alkaline peroxide