High Intensity Resistance and Aerobic Training Among Women With PCOS
Condition: Polycystic Ovary Syndrome
MeSH terms: Polycystic Ovary Syndrome; Syndrome
Study type: Interventional

Summary: 
      polycystic ovarian syndrome (PCOS) is the most common endocrine female disorder, affecting
      4-18% women of reproductive age. The prevalence of PCOS in South Asian women, especially in
      Pakistani women, is much higher (52%) as compared to white population (20 - 25% in UK). On
      the basis of cultural, environment, diet and lifestyle practices these women are more prone
      to development of such disorder. So such public health issue needs to be addressed by strong
      evidence conducted by a clinical trial. The current study is planned to compare effects of
      two different exercise protocols of high intensity on anthropometric measures, hormonal
      profile and quality of life.
    

Detailed description: 
      PCOS is a prevalent condition that is affecting adolescent girls now and has serious impacts
      on menstrual health and quality of life making them prone to early risk development for
      chronic metabolic diseases. The comparison between high intensity resistance and aerobic
      training would give results that which one is more effective in gaining benefits and better
      effects on overall health both physically(menstrual) as well as mentally that would
      eventually tell us about the quality of life of such patients.

      After the initial screening process, the participants fulfilling the Roterdam criteria,
      willing to participate in the exercise trial will be recruited and then randomized to the
      allocated groups of either high intensity resistance or high intensity aerobics. At baseline,
      their anthropometrics measurements, LH/FSH ratios and fasting plasma glucose test will be
      done. Patient will be called thrice a week for 3 months for training. It is hypothesized that
      high intensity resistance or high intensity aerobics will improve anthropometric measures
      along with hormonal profile and quality of life.
    

Intervention name(s): High intensity resistance Exercise Training; High intensity aerobic Exercise Training
Intervention type(s): Other; Other
Intervention description(s): The resistance training will consist of five resistance exercises (thrice a week on non-consecutive days): squat, leg press, knee extension, lunges, and abdominal crunches. Every participant will be assessed pre and post intervention for hormonal change, BMI/anthropometric measures, fasting glucose and quality of life.The plan will be followed for 12 weeks; The training protocol will begin with a 5-minute warm-up and will end with a 5-minute cool down, during which the HR will be 60-75% of the HRmax. At least 90 min of exercise per week for obese PCOS patients, with treadmill walking that may include whole-body movement involving more than 2/3 of the muscles, the exercise intensity will be high intensity
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Parallel assignment into two groups
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment