Comparison of Effect of Prolotherapy and Paraffin Waxes for Hand Osteoarthritis
Condition: Hand Osteoarthritis
MeSH terms: Osteoarthritis
Study type: Interventional

Summary: 
      Patients with hand osteoarthritis will be randomized into two groups, paraffin wax and
      prolotherapy group. Patients will be evaluated before and after treatment , after 2 weeks 4
      weeks and 3 months after treatment. Evaluation parameters are visual analog scale, Duruoz
      hand index scales, grip strength, lateral pinch, two point pinch and three point pinch
      strengths.
    

Detailed description: 
      This study is a randomized clinical trial. 40 Patients with hand osteoarthritis will be
      randomized into 2 groups, paraffin wax and prolotherapy group.Paraffin group patients will be
      told to take of jewellery and dip their hands into the bath of melted wax (52 ºC) with hands
      open and hand wrist in neutral position for 10 times .In paraffin wax group, patients will be
      treated 5 days a week for 2 weeks period. Paraffin wax bath will be applied for 20 minutes in
      every physical therapy session. Prolotherapy is a nonsurgical regenerative injection
      technique that introduces small amounts of an irritant solution to the site of painful and
      degenerated tendon insertions (entheses), joints, ligaments, and in adjacent joint spaces
      during several treatment sessions to promote growth of normal cells and tissues.Hypertonic
      dextrose solution is most common used agent. In prolotherapy group, %15 dextrose solution
      will be applied to medial and lateral aspect of proximal interphalangeal joints (PIJ), distal
      interphalangeal joints and carpometacarpal joint of thumb for 3 sessions once a week period.
      Grip strength, lateral pinch, two point pinch, three point pinch strengths, Visual analog
      scale (VAS), Duruoz Hand Index scales will be assessed before the intervention and after two
      weeks, 4 weeks and 3 months after intervention .
    

Intervention name(s): Paraffin wax; Prolotherapy
Intervention type(s): Other; Drug
Intervention description(s): Paraffin group patients will be told to take of jewellery and dip their hands into the bath of melted wax (52 ºC) with hands open and hand wrist in neutral position for 10 times .In paraffin wax group, patients will be treated 5 days a week for 2 weeks period. Paraffin wax bath will be applied for 20 minutes in every physical therapy session.; . Prolotherapy is a nonsurgical regenerative injection technique that introduces small amounts of an irritant solution to the site of painful and degenerated tendon insertions (entheses), joints, ligaments, and in adjacent joint spaces during several treatment sessions to promote growth of normal cells and tissues.Hypertonic dextrose solution is most common used agent. In prolotheraphy group, %15 dextrose solution will be applied to medial and lateral aspect of proximal interphalangeal joints (PIJ), distal interphalangeal joints and carpometacarpal joint of thumb for 3 sessions once a week period
Other intervention name(s): paraffin
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Single (Investigator)
Primary purpose: Treatment
Keywords: paraffin; prolotherapy; hand osteoarthritis