Efficacy of Bioptron Light Therapy (BLT) on Post Chemotherapy Oral Mucositis
Condition: Oral Mucositis (Ulcerative)
MeSH terms: Mucositis; Stomatitis
Study type: Interventional

Summary: 
      The study aimed to study the effect of Bioptron light therapy (BLT) on oral mucositis after
      receiving chemotherapy in patients with head and neck cancer,Oral mucositis (OM) is a common
      and severe acute side-effect of many oncologic treatments, especially in patients treated for
      head and neck cancer. It affects quality of life and require supportive care and proper
      treatment plane.

      This study had been conducted on thirty cancer patients (head &neck) receiving chemotherapy &
      radiotherapy (males and females) with oral mucositis with ulceration and pain(grade 2 and
      more), their age ranged from 35 to 55 years, capable of understanding the study assessment
      method and willing to complete the current study, they were free from any immunodeficiency
      disorders or diseases that could impair the healing process and impact the results as
      diabetes mellitus. Patients were randomly allocated from patients from the National Cancer
      Institute, Cairo University. Group A (BLT group): This group consisted of 15 patients
      receiving BLT for about 10 minutes every day for thirty days in addition to routine oral
      mucositis medical care (Analgesics, anti-inflammatory treatment and antimicrobial treatment
      for any new mouth infections), Group B (Control group): This group consisted of 15 patients
      receiving daily routine oral mucositis medical care(Analgesics, anti-inflammatory treatment
      and antimicrobial treatment for any new mouth infections) for thirty days The methods of
      evaluation in the current study were the WHO oral mucositis scale (OMS) and the Common
      toxicity criteria scale (CTCS). At the same time, the treatment equipment was the polarized
      light therapy device Bioptron Compact III (PAG-860 manufactured in Switzerland) Assessment by
      WHO oral mucositis scale and (OMS) and (CTCS) were used before treatment and after treatment
      to measure improvement in oral mucositis.

      The results of WHO oral mucositis scale (OMS) and the Common toxicity criteria scale (CTCS)
      were assessed first at the beginning of the study and one month after the end of the study;
      calculation of mean, standard deviation, minimum and maximum for each group was done by
      descriptive statistics, means comparison between the two groups pre and post-application and
      within each group was made using The t-test. With a level of significance Alpha point of 0.05
    


Intervention name(s): Bioptron Light Therapy (BLT)
Intervention type(s): Other
Intervention description(s): BLT for 30 days 10 minutes every day. The treatment points displayed were: one point in the right jugal mucosa, one point in the left jugal mucosa, one point in the lower lip 's inner mucosa, analgesics, anti-inflammatory treatment, and antimicrobial treatment for any new mouth infections)
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Treatment