Prevalence of Onychodystrophy in Patients With Chronic Venous Disease of the Lower Limbs
Condition: Lower Extremity Chronic Venous Insufficiency; Onychodystrophy
MeSH terms: Venous Insufficiency
Study type: Observational [Patient Registry]

Summary: 
      The objective of this study is to determine the degree of correlation between the clinical
      severity of chronic venous disease and the prevalence of onychodystrophy. The completion of
      the study will require a previous synthetic explanation of the aforementioned two diseases,
      emphasizing the factors which have an impact on the proposed analysis.
    

Detailed description: 
      The ultimate goal of this work is to determine if patients with a higher clinical severity of
      chronic venous disease also present a higher prevalence of onychodystrophy. Chronic venous
      disease (CVD) is a vascular disease that manifests itself in the lower limbs and is related
      to a number of different clinical syndromes, all of which have venous hypertension (HTV) in
      common.

      Onychodystrophy in the lower limbs is a progressive non-infectious condition associated with
      various factors the prevalence of which increases with age.It is mainly an acquired
      condition, but it can also be congenital. It is associated to a number of factors, it can
      sometimes be asymptomatic and it is progressive, non transmittable and evolves at a slow
      pace. It is characterised by an abnormal pigmentation, changes in the shape or texture and/or
      the deformation of nails.

      The work performed was observational, cross-sectional, analytical, inferential and
      unicentric. In order to prove its feasibility, the researcher conducted a preliminary
      investigation work (pilot study) with a total of 40 patients (aged 40 to 85) who were treated
      at the Service of Angiology and Vascular Surgery of the Hospital de Sant Pau (Barcelona,
      Spain). These patients were selected to verify their data and then the researcher performed a
      statistical study from a descriptive and inferential point of view to find out whether there
      is a relation betwen the prevalence of onychodystrophy and the degree of severity of chronic
      venous disease. In order to minimise methodological mistakes in the outcomes and sampling,
      the study has been carefully defined and framed.
    

Intervention name(s): observational cross-sect. analytical inferential unicentric
Intervention type(s): Other
Intervention description(s): collecting data from patients of the Service of Angiology and Vascular Surgery of the Hospital de Sant Pau
Other intervention name(s): collecting data
Observational model: Other
Time perspective: Cross-Sectional
Sampling method: Probability Sample
Study population: 
        After the collection of the data, the researcher will establish the variables, including
        all clinical data, the Doppler echography data, the CVD symptoms, and the class to which
        the subject belongs according to the CEAP Classification ( ranging from 0 to 6). All these
        data will be analyzed in relation to the presence of onychodystrophy in each patient. Other
        variables that can be related to onychodystrophy will also be registered: type of footwear,
        feet deformation, personal history and local factors considered potentially responsible for
        the presence of onychodystrophy. Finally, the researcher will perform the statistical
        analysis relating all the variables to finally determine whether there exists or not a
        correlation betwen (CVD) and onychodystrophy.
      
Keywords: CEAP classification; CVD: Chronic Venous Disease; Onychodystrophy; Body Mass Index