Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions
Condition: White Spot Lesion of Tooth
MeSH terms: Exanthema
Study type: Interventional

Summary: 
      this study aimed to assess the effect of the application of the low-viscosity Icon resin
      infiltrate on the color change of the diagnosed white spot enamel lesions (WSLs) over 3-, 6-,
      and 12-m follow-up periods. The ICDAS scoring system was used to visually diagnose WSLs in a
      total of 96 anterior teeth in 49 participants and the teeth were then were evaluated for
      their color change using a spectrophotometer. According to the manufacturer directions the
      Icon kit was applied to the WSLs-diagnosed teeth as follows: the WSLs were treated with 15%
      hydrofluoric acid (Icon-Etch) was applied to the lesions for 120 seconds then it was rinsed
      for 30 seconds. Next, the etched WSLs were treated with 99% ethanol (Icon-dry) and for 30
      seconds. Then the Icon-Resin was applied and light cured for 40 seconds. The change of color
      was done after 3-, 6- and 12-month . The mean and standard deviation values were
      statistically analyzed with the repeated measure ANOVA test and the Paired sample t-test.
    

Detailed description: 
      The early caries may not be noticeable till it appears as rough enamel surface that might has
      chalky-white or even dark spots of brown color with no cavities formed. These spots reported
      were referred to as the white spot enamel lesions, that can be visually diagnosed with the
      ICDAS scoring method (International Caries Detection and Assessment System) that was proposed
      for the assessment of caries including early enamel lesions that are not yet cavitated and
      appear after through dryness of the enamel surface.

      Remineralization of the white spots enamel lesion presents the first choice treatment option.
      Still it has some short-outcomes, such as the staining-ability and unreliable esthetic
      results. It was reported that the Icon resin infiltration to masking the white spot enamel
      lesion at the minute of its application without a detectable change of color up to a period
      of six months. The Icon resin infiltration technique depends on its low-viscosity that
      enables its penetration into enamel surface through capillary action, occluding the micro
      porosities created in the enamel as a result of the white enamel lesions development. So
      that, the progression of the lesion would be stopped.

      Therefore, this clinical study was conducted to assess the effectiveness of the application
      of the Icon resin infiltration on the change of the color change of the white spot enamel
      lesions at follow-up periods of 3-, 6-, and 12-months.
    

Intervention name(s): Icon resin application
Intervention type(s): Other
Intervention description(s): Application of the low-viscosity resin infiltration (Icon) to the white spot enamel lesions
Intervention model: Single Group Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Low-viscosity resin infiltration; Icon; color change; white spot enamel lesions