Remote Monitoring in Parkinson's Disease
Condition: Parkinson Disease
MeSH terms: Parkinson Disease
Study type: Interventional

Summary: 
      The goal of this observational study is to learn about the usefulness of physical activity
      measures and tremor detection using wearable devices and smartphone video to detect and
      evaluate disease burden in people with Parkinson's disease.

      Participants will wear an activity tracker at home and complete a short research visit where
      they will make a video using a smartphone of themselves performing a fine motor task. They
      will wear the activity tracker for two weeks at home.
    

Detailed description: 
      For all groups (there is no control group):

      At enrollment, the participants will complete a baseline survey that records participant sex,
      years since the diagnosis of Parkinson's disease, current use of levodopa medication, and
      whether levodopa was taken today.

      Next, a research nurse from neurology will complete the Unified Parkinson's Disease Rating
      Scale (UPDRS) assessment. As part of this assessment, the researchers will make a video
      recording of Part 3 (the motor assessment) as a gold standard for comparison with the
      participant-recorded videos.

      Next, the participant will complete the PDQ-39 (Parkinson's disease questionnaire), a 39 item
      questionnaire about the quality of life.

      After completing the PDQ-39, the researchers will provide the participant with a camera,
      small tripod, and a set of written directions about how to perform the UPDRS motor
      assessment. The goal with this task is to simulate a home recording session to uncover any
      issues and create preliminary data for validation of the home recording compared to the gold
      standard collected by the study team. The recordings will then be converted to x, y, z
      landmarks using MediaPipe, running on UIowa hardware.

      After completing the video, the participant will complete a short survey about ease of making
      the video recording.

      After completing the baseline assessments, the research team will provide the participant
      with a Fitbit Inspire 3 activity tracker watch, configure the tracker to sync with their
      phone, and provide an overview of use.

      The participant will wear the activity tracker for 24 hours a day for the next 14 days except
      for if the device needs charging and when bathing.

      At 14 days, the research team will send participants a link to complete a web-based exit
      survey about their experience with the activity tracker during the study.
    

Intervention name(s): Video and Activity Tracker
Intervention type(s): Other
Intervention description(s): At enrollment, the participants will complete a baseline survey, PDQ-39 (Parkinson's disease questionnaire), and the Unified Parkinson's Disease Rating Scale (UPDRS) assessment. The researchers will provide the participant with a camera, small tripod, and a set of written directions about how to record the UPDRS motor self-assessment video.
After completing the baseline assessments, the research team will provide the participant with a Fitbit Inspire 3 activity tracker watch. The participant will wear the activity tracker for 24 hours a day for the next 14 days except for if the device needs charging and when bathing.
At 14 days, the research team will send participants a link to complete a web-based exit survey about their experience with the activity tracker during the study.
Intervention model: Single Group Assignment
Masking: None (Open Label)
Primary purpose: Other