Calorie Restricted Diet and Exercise
Condition: Metabolic Syndrome
MeSH terms: Metabolic Syndrome; Syndrome
Study type: Interventional

Summary: 
      Calorie-restricted(CR) diet and exercise were effective to reduce Metabolic syndrome(MetS),
      however, its effect on knee functions for MetS patients with degenerate meniscus
      lesions(DMLs) was still poorly investigated.
    

Detailed description: 
      The CR diet and exercise group received a balanced diet with an energy consists carbohydrates
      45-65%; fat 20-35%; and protein 10- 35% and a deficit of 600 kcal/day from their daily energy
      requirement. Total daily energy intake of 1200-2000 kcal/day were based on baseline weight,
      and for safety, no woman was provided with less than 1100 kcals/d and no man less than 1300
      kcals/d. The energy of the intake calorie restricted diet per day was calculated based on the
      detailed composition of meals, such as rice, vegetables, eggs, pork, and beef, using the
      Chinese food composition tables. Our diets were cooked with traditional Chinese cooking
      methods such as boiling, stir-frying, and stewing. During the intervention, other
      lipid-lowering drugs were not allowed to intake supplement as it alters the outcome.
      Participants receive education or counseling by a dietitian for modulations of their caloric
      intake weekly.

      The exercise intervention included aerobic exercises and resistance exercise, flexibility
      exercises about 150 minutes for ≥2 d/week for 6 months. The aerobic exercises included
      walking on a treadmill, stationary cycling for at least 30 minutes for≥2 d/week. Resistance
      exercises included nine upper-extremity and lower-extremity exercise with weighting lift
      machines for ≥2 d/week, while, flexibility exercise including the major muscle-tendon groups
      (a total of 60 s per exercise) for ≥2 d/week. Participants performed 1 or 2 sets with 8-12
      repetitions of each exercise. The exercise sessions were monitored by telephone video.
      Patients who complete at least 80% of diet restriction and exercise were included in
      analysis. Calorie restricted diet and exercise group contain both the above intervention.
    

Intervention name(s): calorie restricted diet and exercise; exercise alone
Intervention type(s): Behavioral; Behavioral
Intervention description(s): The CR diet and exercise group received a balanced diet with an energy consists carbohydrates 45-65%; fat 20-35%; and protein 10- 35% and a deficit of 600 kcal/day from their daily energy requirement.The exercise intervention consists of aerobic exercises and resistance exercise, flexibility exercises about 150 minutes for≥2 d•wk for six months. The aerobic exercises included walking on a treadmill, stationary cycling for at least 30 minutes for≥2 d•wk, while, resistance exercises included nine upper-extremity and lower-extremity exercise with weighting lift machines for ≥2 d•wk, while, flexibility exercise including the major muscle-tendon groups (a total of 60 s per exercise) for ≥2 d•wk. Participants performed 1 or 2 sets with 8-12 repetitions of each exercise. The exercise sessions were monitored by telephone video.; In exercise alone group, participants then underwent their usual habitual dietary diet and the above exercise intervention during the program.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary purpose: Treatment