Study of the Effect of the VR Technology on Recovery of the Autonomic Nervous System in Volunteers Affected by Stress
Condition: Stress
Study type: Interventional

Summary: 
      The study assess the effect of the VR technology (Pure Purr technology) on the recovery of
      the autonomic nervous system in healthy volunteers affected by moderate stress. Study subject
      randomized into two groups: in Group 1 volunteers first be tested with the VR headset A, and
      during the next visit- headset B. Group 2 volunteers first be tested with the VR headset B,
      and during the next visit- headset A. Before, after and during VR session was conducted
      stress modulation and ECG recording.

      The Pure Purr technology combines several audio and visual stimuli aimed at activation of the
      parasympathetic nervous system. Therefore, this study will investigate the effect of this
      technology on the recovery of autonomic nervous system performance after moderate stress.
    

Detailed description: 
      Pure Purr technology is based on discoveries in neurophysiology, medicine, acoustics, and
      computer engineering, which are used to initiate the physiological process of recreation,
      i.e. allostasis. Literally this term means "achieving stability through change". This is an
      active mechanism playing a part in normalization of the tone of the autonomic nervous system
      and maintaining stability of the body internal environment. The condition in which all our
      functions are implemented fully and sparingly in response to the load, and the level of
      adaptation remains high for a long time. Pure Purr is a software and hardware complex for
      relaxation and recreation based on a virtual reality headset with a display with sufficient
      resolution, built-in processor, memory, and extended-range stereo speakers. Positive effect
      on the cognitive function of the brain and the system of neurohumoral regulation is achieved
      due to the synchronous actuation of a number of stimuli, such as: visual sequence enhanced by
      the effect of virtual reality, harmonious music with the binaural rhythm technology, and
      modified cat purrs. Currently, the use of each technology is a scientifically proven trigger
      for the activation of individual parts of the human nervous system. And combining them in one
      software complex enhances the overall effect.
    

Intervention name(s): Pure Purr VR technology; Sham VR technology
Intervention type(s): Device; Device
Intervention description(s): The Pure Purr technology consists of BoboVR X1 headset with pre-installed software. The virtual reality headset reproduces a dynamic video content that is visually perceived with the help of the high-resolution screen. Also, the headset is able to play audio and transmit it via the headphones.
The audio sequence has been modified by adding a binaural effect and has been synchronized with the tact of respiratory movements and the frequency of heart rate.; The sham technology includes an identical BoboVR X1 virtual reality headset with pre-installed software. The audio-visual sequence is similar to the one in the investigational version of the software. The key difference is that the audio sequence has not been modified with the binaural effect and has not been synchronized with the tact of respiratory movements and the frequency of heart rate.
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Single (Investigator)
Primary purpose: Other
Keywords: VR; moderate stress