Adolescent Outpatient and Continuing Care Study
Condition: Substance Abuse; Substance Dependence
MeSH terms: Substance-Related Disorders
Study type: Interventional
Phase: Phase 3

Summary: 
      The purpose of this study was to evaluate the effectiveness and cost-effectiveness of two
      types of outpatient treatment with and without Assertive Continuing Care (ACC) for 320
      adolescents with substance use disorders. Study participants were randomly assigned to one of
      four conditions: (a) Chestnut's Bloomington Outpatient Treatment (CBOP) without ACC; (b) CBOP
      with ACC; (c) Motivational Enhancement Therapy/Cognitive Behavior Therapy-7 session model
      (MET/CBT7) without ACC; and (d) MET/CBT7 with ACC. Based on prior quasi and experimental
      studies, the investigators hypothesized that MET/CBT would be more effective and
      cost-effective than CBOP in terms of increasing days abstinent and decreasing substance abuse
      problems. Additionally, the investigators hypothesized that the groups receiving ACC would
      have significantly better outcomes than the groups without ACC. Lastly, the investigators
      hypothesized that adding ACC to MET/CBT would be the most cost-effective option in terms of
      days abstinent.
    

Detailed description: 
      This study evaluated the effectiveness and cost-effectiveness of two types of outpatient
      treatment with and without Assertive Continuing Care (ACC) for 320 adolescents with substance
      use disorders. Study participants were randomly assigned to one of four conditions: (a)
      Chestnut's Bloomington Outpatient Treatment (CBOP) without ACC; (b) CBOP with ACC; (c)
      Motivational Enhancement Therapy/Cognitive Behavior Therapy-7 session model (MET/CBT7)
      without ACC; and (d) MET/CBT7 with ACC. All study conditions attained high rates of
      participant engagement and retention. Follow-up interviews were completed with over 90% of
      the adolescents at three, six, nine, and 12 months after treatment admission. There was a
      significant time by condition effect over 12 months, with CBOP having a slight advantage for
      average percentage of days abstinent. Unlike previous findings that ACC provided incremental
      effectiveness following residential treatment, there were no statistically significant
      findings with regard to the incremental effectiveness of ACC following outpatient treatment.
      Analysis of the costs of each intervention combined with its outcomes revealed that the most
      cost-effective condition was MET/CBT7 without ACC.
    

Intervention name(s): Chestnut Bloomington Outpatient (CBOP); Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7); Assertive Continuing Care (ACC)
Intervention type(s): Behavioral; Behavioral; Behavioral
Intervention description(s): CBOP is an evidence-informed intervention that has developed over 20 years and been shaped by treatment research. The underlying theory of change is that the combination of multiple evidence-based and best-practice treatment components will increase the adolescent's desire to change, provide the necessary skills, and create an environment supportive for this change. The intervention is based on a manual and is primarily delivered through skill and therapy groups, combined with a limited number of family and individual sessions for treatment planning and progress reviews.; A manual-based 5-session MET/CBT model was supplemented with 2 family sessions. First was a family session to provide parents with an overview. Next was an individual adolescent MET session that focused on building rapport, explaining treatment, building motivation, and reviewing personalized feedback. In the third session, the therapist helped the adolescent complete a functional analysis of substance use and a personal goal worksheet. During sessions 4-6, the adolescent joined a closed group of 6 for 90-min CBT skills groups focusing on substance refusal skills, enhancing social support, planning for high-risk situations, and coping with relapse. The last session was a family session to review progress, relapse signs, and continuing care plans. Treatment lasted about 12 weeks.; ACC is a home-based continuing care approach that takes place over a 12-14 week period and has shown promise in a randomized clinical trial of adolescents discharged from residential treatment. Following an operant reinforcement and skills training model, ACC combines the Adolescent Community Reinforcement Approach and case management services to help adolescents and their caregivers engage in prosocial activities, skills, and needed community services during weekly home visits.
Allocation: Randomized
Intervention model: Factorial Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Substance abuse; Adolescent outpatient treatment; Continuing care; Outcomes