Therapeutic Termination of Pregnancy and Psychiatric Implications
Condition: Therapeutic Abortion With Complications; Personality Disorders; Trauma, Psychological; Reproductive Behavior; Post Traumatic Stress Disorder; Depression, Reactive
MeSH terms: Depression; Stress Disorders, Traumatic; Stress Disorders, Post-Traumatic; Personality Disorders; Psychological Trauma; Adjustment Disorders
Study type: Observational

Summary: 
      25 parental couples, with a prenatal diagnosis of fetal abnormality, had psychiatric
      evaluation for eligibility before TToP and after one year from the procedure. Women and
      unborn's fathers were also subjected to different psychometric questionnaires (HAM-D, HAM-A,
      BDI-II, PCL-5, IPDS, CTQ, CD-RISC-10).
    

Detailed description: 
      The therapeutic interruption of pregnancy (TTOP) may have psychiatric outcomes like
      depression, anxiety and post-traumatic stress disorder (PTSD). Personality issues, childhood
      traumas and paternal consequences are too little investigated in current Literature.

      The investigator's aim is exploring the contribution of maternal personality disorders and
      maternal history of childhood traumas to psychiatric outcomes after a TToP, paternal
      psychiatric outcomes and their role on their partner's psychopathological and psychiatric
      outcomes.

      25 couples, with a prenatal diagnosis of fetal abnormality, had psychiatric evaluation for
      eligibility before TToP and after one year from the procedure. Women and unborn's fathers
      were also subjected to different psychometric questionnaires (HAM-D, HAM-A, BDI-II, PCL-5,
      IPDS, CTQ, CD-RISC-10).

      At the time of first contact (T0) only women were subjected to a psychiatric clinical
      examination in order to evaluate their legal eligibility to TToP, according to Italian Law n.
      194/78. At T0 women were also subjected to Hamilton's rating scale for depression (HRSD or
      HAM-D), Hamilton's rating scale for anxiety (HRSA or HAM-A), Beck Depression Inventory
      (BDI-II). At the follow up after 1 year from the first examination (T1) the parental couples
      were subjected to a questionnaire with multiple psychometric tests for mother and her
      partner. The female version included Post-traumatic stress disorder checklist (PCL-5), Iowa
      Personality Disorder Screen (IPDS), Beck Depression Inventory (BDI-II), Connor-Davidson
      Resilience Scale 10 (CD-RISC 10) and Short-Form Questionnaire on childhood trauma (CTQ-SF).
      The male version included Post-traumatic stress disorder checklist (PCL-5), Iowa Personality
      Disorder Screen (IPDS), Connor-Davidson Resilience Scale 10 (CD-RISC 10) and Short-Form
      Questionnaire on childhood trauma (CTQ-SF).
    

Intervention name(s): Multiple psychometric questionnaire; Clinical psychiatric examination
Intervention type(s): Diagnostic Test; Procedure
Intervention description(s): At the time of first contact (T0) only women were subjected to Hamilton's rating scale for depression (HRSD or HAM-D), Hamilton's rating scale for anxiety (HRSA or HAM-A), Beck Depression Inventory (BDI-II). At the follow up after 1 year from the first examination (T1) they were subjected to a questionnaire with multiple psychometric tests for mother and her partner. The female version included Post-traumatic stress disorder checklist (PCL-5), Iowa Personality Disorder Screen (IPDS), Beck Depression Inventory (BDI-II), Connor-Davidson Resilience Scale 10 (CD-RISC 10) and Short-Form Questionnaire on childhood trauma (CTQ-SF). The male version included Post-traumatic stress disorder checklist (PCL-5), Iowa Personality Disorder Screen (IPDS), Connor-Davidson Resilience Scale 10 (CD-RISC 10) and Short-Form Questionnaire on childhood trauma (CTQ-SF).; At the time of first contact (T0) only women were subjected to psychiatric clinical examination
Observational model: Cohort
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        45 parental couples (90 subjects: 45 women and 45 men) with a prenatal diagnosis of fetral
        abnormality followed by Obstetrical Department of ASST Monza
      
Keywords: Therapeutic Abortion; Personality Disorders; Childhood Trauma; Post Traumatic Stress Disorder; Depression