Non-carious Cervical Lesions and Treatments
Condition: Tooth Sensitivity
MeSH terms: Dentin Sensitivity
Study type: Interventional

Summary: 
      This study will compare clinically the efficacy, time to action and duration of different
      treatments for patients with non-carious cervical lesions (NCCLs) that caused dentin
      hypersensitivity (DH).
    

Detailed description: 
      This study will compare clinically the efficacy, time to action and duration of different
      treatments for patients with non-carious cervical lesions (NCCLs) that caused dentin
      hypersensitivity (DH). Casuistic and methods: 60 participants with NCCLs and positive for DH
      will be enrolled in the study to receive randomly the followed treatments: LA= 780 nm and
      70mW GaAlAs Laser/ 4 sessions; LAP= placebo laser/ four sessions; RGI= ClinproTM XT Varnish/
      in-office single session; RX= adhesive RelyXTM Arc/ in-office single session; DE= stannous
      fluoride dentifrice/30-days-home-use; DE-P= placebo dentifrice/30-days-home-use. Pain from DH
      is measured with visual analogue scale (VAS), pre-treatment and in accordance with each
      treatment, immediately after the end of the treatment (S1); one and two weeks (1S and 2S) and
      one and two months (1M and 2M) after the end of the treatments. Strategies of treatments are
      compared each other in each period of evaluation and along time with pre-treatments values of
      pain, using Kruskall-Wallis and Friedman Test (p<0.05).
    

Intervention name(s): Experimental: • Group LA; Placebo Comparator: • Group LA-P; Experimental: • Group DE; Placebo Comparator: • Group DE-P; Experimental: • Group RGI; Experimental: Group RX
Intervention type(s): Device; Device; Other; Other; Other; Other
Intervention description(s): to apply Laser (780 nm and 70mW) at the cementum-enamel junction fat the teeth affected by sensitivity; to apply Laser (780 nm and 70mW) at the cementum-enamel junction at the teeth affected by sensitivity with the laser device having no effective laser emission, only guided by light; to brush teeth with a blinded dentifrice with 0,45% of stannous fluoride and a soft-bristled manual toothbrush (Johnson & Johnson®).; to brush teeth with a blinded dentifrice with 1500 ppm of available fluoride and a soft-bristled manual toothbrush (Johnson & Johnson®).; to apply a thin layer of resin based glass-ionomer product on the cervical surface of the affected teeth affected by sensitivity following the manufacturer instructions.; to apply Adper Single Bond Plus Adhesive in accordance with the manufacturer instructions, at the teeth affected by sensitivity product for 20 seconds.
Other intervention name(s): low laser therapy; low laser therapy; desensitizing dentifrice; placebo desensitizing dentifrice; resin glass ionomer restorarion; selant with resin cement
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: 60 participants with NCCLs and positive for DH are enrolled in the study to receive randomly the followed treatments: LA= 780 nm and 70mW GaAlAs Laser/ 4 sessions; LAP= placebo laser/ four sessions; CP= ClinproTM XT Varnish/ in-office single session; RX= adhesive RelyXTM Arc/ in-office single session; DE= stannous fluoride dentifrice/30-days-home-use; DE-P= placebo dentifrice/30-days-home-use
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Non-carious cervical lesions; dentin hypersensitivity