Obsessive-compulsive Symptoms in Children and Adolescents With Anorexia Nervosa
Condition: Anorexia Nervosa
MeSH terms: Anorexia; Anorexia Nervosa
Study type: Interventional

Summary: 
      The purpose of this study is to determine obsessive-compulsive symptoms and BMI changes in
      children and adolescents with anorexia nervosa and find out whether there is a group-level
      correlation between the two. We also investigate a possible link between obsessive compulsive
      symptoms and the psychological features of eating disorders.

      It is a national, academic, interventional study. The data will be acquired through
      questionnaires.
    

Detailed description: 
      Children and adolescents with anorexia nervosa show a high psychiatric co-morbidity. In
      clinical practice, compulsions and compulsive thoughts are frequently reported in children
      and adolescents with anorexia nervosa. Obsessive compulsive disorder occurs in 19% of
      patients with anorexia nervosa and anorexia nervosa is seen in 3-17% of female patients with
      obsessive compulsive disorder.

      A precise explanation for this coexistence is still unknown.An underlying genetic correlation
      and common neuropsychological factors and personality traits are described in the literature
      as possible explanations. Little is know about the relation between obsessive compulsive
      symptoms and the psychological features of eating disorders.

      It is also unclear whether obsessive compulsive symptoms can be seen as a result of the
      underweight and weight loss associated with anorexia nervosa and whether these symptoms clear
      up with weight recovery. Research on this is very limited and shows different results. The
      aim of this study is to examine obsessive compulsive symptoms and weight change in children
      and adolescents with anorexia nervosa and to determine whether there is a group-level
      correlation between the two.

      It is a national, academic, interventional study. The data will be acquired through the
      following questionnaires:

        -  Questionnaires to be completed by the minor:

             -  Dutch version of the Children's Yale-Brown Obsessive Compulsive Scale (CYBOCS,
                Goodman W.K. e.a., vertaald en bewerkt door Lidewij Wolters en Else de Haan, DAT de
                Bascule, juni 2012, existing of two parts CY-BOCS Symptom Checklist en CY-BOCS
                Severity Ratings)

             -  Dutch version of the Eating Disorder Inventory-3 (EDI-3, David M. Garner,
                Nederlandse vertaling door Tatjana van Strien, Hogrefe Uitgevers B.V. Amsterdam,
                2014)

        -  Questionnaires to be completed by the parent or guardian:

             -  General questionnaire: personal data, family and school and social information,
                child psychiatric history

             -  Dutch version of the problem part of the Child Behavior Checklist (CBCL, T.M.
                Achenbach, Nederlandse vertaling door F.C. Verhulst en J. van der Ende, Erasmus MC
                - Sophia Kinderziekenhuis Rotterdam, 2001)

             -  Anorectic Behavior Observation Scale (ABOS, Vandereycken W., Universitair Centrum
                Kortenberg, 1992)

             -  Consent Form to contact if the completed questionnaires have increased results
    

Intervention name(s): Questionnaires
Intervention type(s): Other
Intervention description(s): Administered Questionnaires:
Dutch version of Children's Yale-Brown Obsessive Compulsive Scale (CYBOCS, Goodman W.K. e.a.)
Dutch version of Eating Disorder Inventory-3 (EDI-3, David M. Garner)
General Questionnaire: demografic , scholar and social information and child psychiatric history
Dutch version of the Child Behavior Checklist (CBCL, T.M. Achenbach)
Anorectic Behavior Observation Scale (ABOS, Vandereycken W., Universitair Centrum Kortenberg, 1992)
Intervention model: Single Group Assignment
Intervention model description: A national, academic, interventional study. The data will be acquired through questionnaires.
Masking: None (Open Label)
Primary purpose: Other
Keywords: obsessive compulsive symptoms