Effects of Routine Physical Therapy With and Without Proprioceptive Neuromuscular Facilitation on Balance, Gait and Function in Patients With Parkinson's Disease
Condition: Parkinson Disease
MeSH terms: Parkinson Disease
Study type: Interventional

Summary: 
      Objective of this study is to compare the effectiveness of routine physical therapy with and
      without Proprioceptive Neuromuscular Facilitation on Balance, gait and function in patients
      with Parkinson's disease.

      Alternate hypothesis:

      There will be a difference in the effects of routine physical therapy with and without
      proprioceptive neuromuscular facilitation on balance, gait and function in patients with
      Parkinson's disease.

      Null hypothesis:

      There will be no difference in the effects of routine physical therapy with and without
      proprioceptive neuromuscular facilitation on balance, gait and function in patients with
      Parkinson's disease.
    

Detailed description: 
      It will be a prospectively registered, parallel designed, single blinded randomized
      controlled trial with concealed allocation, conducted in University of Lahore Teaching
      Hospital and Sir Ganga Raam hospital, Lahore, Pakistan. Patients who met eligibility criteria
      will be informed about the aim of study.consent form will be signed by all eligible
      participants. Eligibility of participants will be confirmed by the physiotherapist of
      research team before randomization. After baseline assessment, eligible patients will be
      randomly allocated(in a 1:! ratio) in two groups( group A and group B). Fish bowl method of
      randomization will be used and will be done by one of the research team members who will not
      involve in patient recruitment or assessment or data analysis.

      Randomization assignments will be kept in opaque, sealed envelopes for concealment of group
      allocation and will be unsealed by researcher after baseline testing. Researchers who assess
      outcomes or will do data analyses will be masked to group allocation.The calculated sample
      size is 32 (16 in each group), after adding 20% dropout the sample size will be 32+6=38, 19
      patients in each group.(statistical power 80% and alpha level of 5%).
    

Intervention name(s): Proprioceptive Neuromuscular Facilitation; Routine physical therapy
Intervention type(s): Other; Other
Intervention description(s): Proprioceptive Neuromuscular Facilitation (PNF) is a more advanced form of flexibility training, which involves both the stretching and contracting of the muscle group being targeted. PNF stretching is one of the most effective forms of stretching for improving flexibility and increasing range of motion.; Routine physiotherapy in Parkinson Disease will be administered according to the European Physiotherapy guidelines for Parkinson Disease and focused on the following areas based on the stage of the disease:Self-management support, prevention of inactivity and fear of falls, maintaining or improving global motor activities, improvement of physical performance, and improvement in the ability to perform transfer, balance, gait, and manual activities, reduce pain, and delay the onset of physical limitations.
Other exercises include:
Range of motion exercises
Stretching exercises
Upper and lower limb strengthening exercises
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: Parkinson' disease; Proprioceptive Neuromuscular Facilitation; Freezing of gait; Berg Balance Scale; Functional Independence Measure; Freezing of Gait Questionnaire