Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral
Condition: Carotid Atherosclerosis; Carotid Stenosis; Ischemic Attack; Stroke; Bleeding
MeSH terms: Carotid Stenosis; Carotid Artery Diseases; Atherosclerosis; Hemorrhage
Study type: Interventional

Summary: 
      The aim is to compare the safety of using transfemoral and transradial approach in patient
      undergoing carotid arteries stenting.
    

Detailed description: 
      The use of transradial approach in carotid arteries stenting can significantly decrease the
      amount of adverse events associated with transfemoral approach such as bleeding or hematoma.
      Otherwise providing transradial approach is fraught with technical difficulties of common
      carotid artery canulation that can result in embolic complications. Taking into account the
      absence of studies in this area of medicine, providing investigation evaluating parameters of
      safety for both methodics is very actual.
    

Intervention name(s): Transradial carotid artery stenting; Transfemoral carotid artery stenting
Intervention type(s): Procedure; Procedure
Intervention description(s): The radial artery is punctured with a trocar. A guidewire is advanced through its lumen, and the trocar is withdrawn. An introducer is passed into the vessel. Then a standard endovascular procedure is carried out under local anesthesia and fluoroscopic control. To prevent cerebral embolism, a protection device is positioned distally of target lesion in internal carotid artery. Then balloon angioplasty of target lesion (if required) is provided. After the angiographic control stent is implanted. After removing all of devices a control angiographic study is provided. Medical therapy includes aspirin(acid acetylsalicylic) 125 - 300 mg/d and plavix (clopidogrel) in dose 300-600 mg prescription before the procedure and heparin sodium injection during the procedure(5000 U iv). After the procedure aspirin(acid acetylsalicylic) in dose 100 mg/d within long period should be prescribed in all the patients, and Plavix (clopidogrel) in dose 75/d should be prescribed within 2 months.; The common femoral artery is punctured with a trocar. A guidewire is advanced through its lumen, and the trocar is withdrawn. An introducer is passed into the vessel. Then a standard endovascular procedure is carried out under local anesthesia and fluoroscopic control. To prevent cerebral embolism, a protection device is positioned distally of target lesion in internal carotid artery. Then balloon angioplasty of target lesion (if required) is provided. After the angiographic control stent is implanted. After removing all of devices a control angiographic study is provided. Medical therapy includes aspirin(acid acetylsalicylic) 125 - 300 mg/d and plavix (clopidogrel) in dose 300-600 mg prescription before the procedure and heparin sodium injection during the procedure(5000 U iv). After the procedure aspirin(acid acetylsalicylic) in dose 100 mg/d within long period should be prescribed in all the patients, and Plavix (clopidogrel) in dose 75/d should be prescribed within 2 months.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Carotid atherosclerosis; Carotid stenosis; Ischemic attack; Stroke; Carotid stenting; Transradial approach; Transfemoral approach; Bleeding; Thromboembolism; Embolism; Neurocognitive disorders