Clinical & Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Primary Root Canal Filling
Condition: Pulp Disease, Dental; Obturation; Root Canal Infection
MeSH terms: Dental Pulp Diseases; Stomatognathic Diseases
Study type: Interventional

Summary: 
      Preserving primary teeth is essential for many aspects such as the child's growth and
      development, esthetic, functional, psychological, and dental arch integrity aspects. a
      randomized blinded controlled clinical trial aimed to evaluate the clinical and radiographic
      success of Zinc Oxide-Ozonated Olive Oil as root canal filling materials for primary molars
      compared to Zinc Oxide-Olive Oil & Zinc Oxide-eugenol. 90 primary molars of 30 children aged
      between 4-8 years with pulpally involved primary molars, are equally divided into 3 groups
      which treated with Zinc Oxide-Ozonated Olive Oil , zinc oxide -olive oil and zinc oxide
      eugenol as obturation materials following pulpectomy procedure. The subjects were followed up
      clinically and radiographically at 3, 6 and 12 months.
    

Detailed description: 
      Pulpectomy for primary teeth involves root canal preparation followed by obturation with a
      resorbable material. Zinc oxide eugenol (ZOE) is the most widely used obturating material.
      The main ZOE disadvantages are the difference in rate of resorption compared to the root, and
      limited antimicrobial activity. ZOE is formed when crude eugenol is mixed with zinc oxide.
      the set material easily hydrolyzes, resulting in free eugenol release which can be harmful to
      human soft tissues; this motivated the search for a new eugenol substitute to be combined
      with zinc oxide. Olive oil is a vegetable oil that comprises antioxidants, carotenoids,
      oleuropein, and oleocanthal, a phenolic component that significantly contributes to its
      antibacterial and anti-inflammatory properties. ozone in the form of ozonated olive oil, have
      the ability to produce nascent oxygen deep into the treated area without triggering
      irritation so, improved rheological characteristics, increased intracellular ATP, stimulated
      cellular metabolism, and expression of cytokines related to healing, particularly
      Transforming Growth Factor.
    

Intervention name(s): pulpectomy procedure and the clinical evaluation; radiographic evaluation
Intervention type(s): Procedure; Radiation
Intervention description(s): in this study, pulpectomy procedure was performed in a single visit and the root canals were filled with different obturating materials. The clinical follow up evaluation was carried out after three, six and twelve months after pulpectomy procedures. The teeth were clinically evaluated each follow up visit for the following clinical features: absence of spontaneous pain, no tenderness with percussion, no abnormal mobility and absence of swelling & sinus or fistula. If the tooth exhibited any one of above clinical features, the pulpectomy was considered to be a failure (F); otherwise, it was regarded as clinical success (S).; Radiographic evaluation was performed immediately after teeth restoration (base line radiograph), then after three, six and twelve months. The parallel periapical technique was performed using the rinn (XCP) periapical film holder and a long cone which was mounted to the x-ray tube. The criteria for radiographic success were no evidence of extensive pathologic root resorption, reduction or no change in pre-operative pathologic inter-radicular radiolucency and no evidence of new postoperative pathologic radiolucency.
Other intervention name(s): clinical evaluation of root canal treatment of primary molars
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary purpose: Treatment
Keywords: pulpectomy; Ozonated Olive Oil; zinc oxide eugenol; primary molars