Bond Apatite in Horizontal Augmentation Versus Bio-Oss
Condition: Horizontal Ridge Deficiency
Study type: Interventional

Summary: 
      Sixteen healthy patients selected from the Outpatient Clinic of the Department of Oral
      Medicine, Periodontology, Diagnosis and Oral Radiology, Faculty of Dentistry, Mansoura
      University for the replacement of missing single maxillary anterior or premolar tooth (in the
      esthetic zone) by dental implant. Patients were selected according to the following criteria:
      1) Patients older than 18 years. 2) Good general health, with no systemic diseases that might
      contraindicate receiving a dental implant. 3) Every patient should have at least one missing
      tooth in the maxillary anterior premolar area and subsequently scheduled for implant
      supported prosthesis. 4) The tooth has been extracted from at least 3 months. 5) Insufficient
      horizontal bone (class III according to Len Tolstunov classification. 6) Good oral hygiene.

      Patients were classified into two groups:

      Group (I) (study group): eight patients with missing anterior or premolar tooth with
      insufficient horizontal (bucco/labio palatal) bone width were treated with dental implants
      and Bond Apatite (AugmaBio, United States of America) as a bone graft material to fill the
      defect.

      Group (II) (positive control group): eight patients with missing anterior or premolar tooth
      with insufficient horizontal (bucco/labio palatal) bone width were treated with dental
      implants and Bio-Oss (Bio-Oss, GeistlichPharmaAG, Wolhusen, Switzerland) as a bone graft
      material to fill the defect and pericardium resorbable membrane.

      Patients were evaluated with the following clinical and radiological parameters presurgical
      and 12 months after operation:

      A) Clinical evaluation:

      The following parameters were evaluated:

        1. Modified plaque index:

           This is fundamentally based on the visual detection of plaque, it ascertains the
           thickness of plaque along the gingival margin, namely the desirability of distinguishing
           clearly between severity and the location of soft debris aggregates.

        2. Modified gingival index:

           It is a method to assess the severity of gingivitis based on gingival color, contour,
           presence of bleeding, stippling and crevicular fluid flow. It is completely noninvasive
           method (only visual).

        3. Probing depth:

      Peri-implant pocket depth was measured using plastic implant probe (contrast PA probe #
      CPNG22, Helmut Zepf Medizintechnik Gmbh®) after final restoration was inserted.

      B) Radiographic evaluation:

      Bone width was assessed using CBCT 12 months after implant insertion. Bone width measurements
      were made on tomographic slices perpendicular to the longitudinal axis of the alveolar crest;
      2 mm from the alveolar crest.
    


Intervention name(s): Bond Apatite; Bio-Oss
Intervention type(s): Other; Other
Intervention description(s): composite graft formed of biphasic calcium sulphate and hydroxyapatite at a ratio of 2:1; xenograft bone substitute
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary purpose: Treatment