Post-operative Pain After Laser Root Canal Treatment of Necrotic Teeth With Apical Periodontitis
Condition: Pulp Necroses; Apical Periodontitis; Pulp Disease, Dental
MeSH terms: Periodontitis; Periapical Periodontitis; Dental Pulp Necrosis; Dental Pulp Diseases; Stomatognathic Diseases; Pain, Postoperative; Necrosis
Study type: Interventional
Phase: Phase 2

Summary: 
      The aim of this study is to evaluate in vivo the post operative pain after laser root canal
      treatment in necrotic teeth in an evidence-based clinical trial. The null hypothesis being
      tested is that there is no difference in post operative pain between conventional irrigation
      and the two types of lasers used.

      Thirty patients are equally divided into 3 separate groups :

        -  Group A (Conventional): 2.5% NaOCL and 17% EDTA.

        -  Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination

        -  Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient
           is given pain scale chart Numeric Rating Scale (NRS) to record his/her pain level before
           any endodontic treatment. All data will be collected, tabulated, summarized, and
           statistically analyzed.
    

Detailed description: 
      Postoperative pain is a common complication following conventional endodontic treatment.
      According to a systematic review, the frequency of endodontic postoperative pain is between
      3% and 58% of patients.Postoperative pain is attributed to chemical, mechanical and
      microbiological factors.

      Residual microorganisms remaining due to the complexity of the root canal system and the
      limited penetration capability of conventional irrigants are directly responsible for Post
      operative pain The aim of this study is to evaluate in vivo the post operative pain after
      laser root canal treatment in necrotic teeth in an evidence-based clinical trial. The null
      hypothesis being tested is that there is no difference in post operative pain between
      conventional irrigation and the two types of lasers used.

      Thirty patients are equally divided into 3 separate groups :

        -  Group A (Conventional): 2.5% NaOCL and 17% EDTA.

        -  Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination

        -  Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient
           will be given pain scale chart (NRS scale) to record his/her pain level before any
           endodontic treatment. After disinfection, local anesthetic, tooth isolation, access
           cavity preparation and final obturation. Patients are asked to mark on a numeric rating
           scale (NRS) to determine incidence of postoperative pain and rate its intensity at 6,
           12, 24, 48, 72 hours, and 7 days after the procedure All data will be collected,
           tabulated, summarized, and statistically analyzed.
    

Intervention name(s): Conventional group; Dual laser group; Combined group
Intervention type(s): Drug; Device; Combination Product
Intervention description(s): conventional disinfection using 2.5% sodium hypochlorite and 17% EDTA; Er,Cr:YSGG intracanal laser irradiation to remove smear layer followed by diode laser for disinfection; 17% EDTA was used to remove smear layer followed by diode laser for disinfection
Other intervention name(s): (NaOCl/EDTA); (Er,Cr:YSGG/Diode); (EDTA/Diode)
Intervention MeSH terms: Edetic Acid
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary purpose: Treatment
Keywords: laser in endodontics; post-operative pain