Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument
Condition: Borderline Personality Disorder
MeSH terms: Personality Disorders; Borderline Personality Disorder
Study type: Observational

Summary: 
      Borderline personality disorder is a mental illness that severely impacts a person's ability
      to regulate their emotions. This loss of emotional control can increase impulsivity, affect
      how a person feels about themselves, and negatively impact their relationships with others.
      In fact, the societal impact of BPDs might be found in emotional suffering, disability and
      economic burden. In addition in BPD, the suicide rate might be as high as 8-10%. the presence
      of BPD also interferes with response to treatment of physical and psychiatric comorbidities,
      such as migraine, HIV, anxiety disorders and substance use disorders. Furthermore, BPD in
      particular, are associated with high rates of unemployment, absences from work and
      inefficiency at work, with only 25% of patients suffering from BPD working full time and 40%
      receiving disability payments. Accordingly, early detection and management would be of great
      societal and economic impact. Our Study aim is to validate the Arabic version of Maclean
      Instrument for screening and detection of BPD and and investigate the possible risk factors
      associated with that disease
    

Detailed description: 
      Borderline personality disorder (BPD) is a mental health problem that affects the way you
      feel about yourself and others, the way you think , difficulty in managing behavior and
      emotions, self-image issues and a pattern of relationships that are unstable. BPD patients
      frequently describe their life as unpredictable and stressful. As stated in the Diagnostic
      and Statistical Manual of Mental Disorders (5th ed.), borderline personality disorder (BPD)
      is a serious mental illness characterized by a pervasive pattern of instability in
      interpersonal relationships, self-image and effect, as well as marked impulsivity. This
      condition arises in early adulthood or adolescence, leading to severe functional impairment
      and subjective discomfort. Unfortunately, diagnosis and treatment of BPD is often delayed,
      leading to a less favorable outcome. This is especially true in patients with early onset
      BPD, in whom the detection and subsequent therapeutic intervention on the disorder is usually
      further put off. Indeed, in the last two decades, there has been a great sensibilization
      towards personality disorder (PD)diagnosis in adolescence, reflected in the significant
      increase in empirical studies regarding this matter, and in the legitimization of adolescent
      PD diagnosis in psychiatric nomenclature (DSM-5 and ICD-11), as well as in national treatment
      guidelines in the UK and Australia. Nonetheless, a recent review by Sharp has stressed how
      scientific evidence and national practice guidelines are yet to penetrate routine clinical
      care. Indeed, in common clinical practice diagnosis and consequently, treatment of BPD is
      usually delayed due to underestimation of symptoms and, often, hesitation to diagnose this
      disorder in younger individuals. BPD is progressively considered a life expectancy formative
      disorder that exists on a layered continuum of severity. The recent studies for the adults
      who have BDP disease couldn't find a pharmacological treatment for them. The symptoms
      treatment with pharmacotherapy is not accurate for the treatment of BDP in adults, the
      pharmacotherapy should not be used for adolescent BPD. The only study exist is about the
      using of omega-3 fatty acids and the increase risk of psychosis. Overall, there is no
      pharmacological treatment for the BDP disease for adults, also the risks of iatrogenic and
      poly-pharmacy toxicity is high in these young people. The other comorbidities of the disease
      are treated from the clinical for adolescents, using the pharmacological therapy when needed.
      Our study aim is to validate the Arabic version of Maclean Instrument for screening and
      detection of BPD and and investigate the possible risk factors associated that disease thus
      decreasing the societal and economic burden of that disease
    

Intervention name(s): no intervention
Intervention type(s): Other
Intervention description(s): no intervention
Observational model: Ecologic or Community
Time perspective: Cross-Sectional
Sampling method: Non-Probability Sample
Study population: 
        adults
      
Keywords: BPD; Maclean instrument; validation; risk factors