High Intensity Resistance Training In Postmenopausal Women (HIRT)
Condition: Post Menopause
Study type: Interventional

Summary: 
      Menopause is defined as a permanent cessation of menstrual cycle for 12 months due to
      intrinsic diminution of ovarian oocytes among women in older age. Globally reported mean age
      for menopause is 48.78 years (ranges from 46-52 years). Menopausal age reported among Asian
      and African population was lower as compared to European women . Among postmenopausal women,
      age related various central nervous system, musculoskeletal, urogenital, metabolic and skin
      changes ensue along with osteoporosis (T-score = ≤ -2.5) and decreased bone mineral density
      due to estrogen deficiency that is directly associated with fragility fractures and
      disability among this age group. Therefore, recruitment of older adults in resistance
      training program is crucial in inducing increases in muscle strength and ameliorating glucose
      tolerance and increased insulin sensitivity along with improvements in BMD and BMR.
    

Detailed description: 
      Physical activity is extremely crucial in maintaining quality of life and estrogen metabolism
      among postmenopausal women, owing to the increased risk of falls, age related decline in
      cardiopulmonary, musculoskeletal endurance and cognitive capacity. In Pakistan, fitness of
      women specifically of postmenopausal age group is ignored due to some cultural norms.
      Performance of physical activity in the form of resistance training (RT) is one of the best
      known methods to improve physical fitness in the elderly. So the current study is planned
      with objectives to determine effects of High Intensity Resistance Training in Postmenopausal
      Women. Supervised exercise training will be provided for 3 months and functional performance
      will be measured accordingly.

      After initial screening of postmenopausal women including history and anthropometric details,
      females meeting inclusion criteria and willing to participate in high intensity resistance
      exercise trial will be recruited in the study. After that; physical fitness, performance base
      testing for functional performance outcome measures and MENQOL assessment will be done at
      baseline and after 3 months. Patients will perform resistance training twice a week, 40-50
      min/session for 12 weeks respectively. It is hypothesized that supervised high intensity
      resistance training will improve functional performance, physical fitness and Quality of life
      among postmenopausal women.
    

Intervention name(s): High Intensity Resistance Training (HIRT); Low-moderate Resistance Exercise Training
Intervention type(s): Other; Other
Intervention description(s): High Intensity Resistance Exercises Supervised High Intensity Resistance Training with 15 minutes of cycling as a warm-up activity then HIRT through Quadriceps drill, Squats, Lunges, Leg press, Biceps curls and Deadlift with 120 seconds of rest interval between each set of exercise and between exercises will be performed by the participants with appropriate cool down through generalized stretching exercises. Participants will perform exercises twice weekly, 40-50 minutes/session for 12 weeks respectively.; Supervised Low-moderate Resistance Training with 15 minutes of cycling as a warm-up activity then Quadriceps drill, Squats, Lunges, Leg press, Biceps curls and Deadlift with 120 seconds of rest interval between each set of exercise and between exercises will be performed by the participants with appropriate cool down through generalized stretching exercises. Participants will perform exercises twice weekly, 40-50 minutes/session for 12 weeks respectively.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: This will be a single factor, Pretest-Posttest Control Group Design with parallel assignment of patients in to two groups.
Masking: Single (Participant)
Primary purpose: Treatment