A Study to Determine if Aquamin (as AquaCal and AquaPT) Improves Digestive Discomfort
Condition: Digestive System Disorders
MeSH terms: Digestive System Diseases; Gastrointestinal Diseases
Study type: Interventional

Summary: 
      Digestive discomfort includes gastrointestinal symptoms such as abdominal pain, altered bowel
      habit, flatulence and bloating and can sometimes result from slower intestinal transit and
      other digestive irregularities.

      The objective of this study is to investigate the effect of consuming Aquamin (as AquaCal and
      AquaPT) on digestive discomfort and symptoms amongst adults without diagnosed
      gastrointestinal disorders.
    

Detailed description: 
      Digestive discomfort includes gastrointestinal symptoms such as abdominal pain, altered bowel
      habit, flatulence and bloating and can sometimes result from slower intestinal transit and
      other digestive irregularities. Digestive discomfort may lead to health issues in the
      long-term. In a recent survey of over 1,000 women in the UK, 88% reported having experienced
      digestive discomfort from time to time, but the majority of them (70%) had never consulted a
      doctor or nurse. Digestive discomfort is often a source of embarrassment for people; they
      therefore may be reluctant to address these issues with a healthcare professional.

      Aquamin is a seaweed-derived mineral source, which is rich in calcium, magnesium and 74 other
      trace minerals including zinc, iron and selenium. It is produced from the red algae,
      Lithothamnion Calcareum, which is found in just three locations in the world, including the
      south-west coast of Ireland and Iceland. During a five-year life span, these algae absorb
      essential minerals from the sea - this gives Aquamin its unique multimineral content. The
      algae then break down naturally and settle on the sea bed. These calcified skeletal remains
      are harvested, washed, dried and milled and provided in a capsule formulation. Aquamin is
      proven to deliver digestive health benefits. In a recent study, mice feed on a high-fat
      'Western-style' diet (HFWD) and Aquamin, suppressed colon polyp formation and a reduction in
      systemic inflammatory changes in comparison to those not receiving Aquamin.

      The objective of this study is to investigate the effect of consuming Aquamin (as AquaCal and
      AquaPT) on digestive discomfort and symptoms amongst adults without diagnosed
      gastrointestinal disorders.
    

Intervention name(s): AquaCal; AquaPT; Placebo
Intervention type(s): Dietary Supplement; Dietary Supplement; Dietary Supplement
Intervention description(s): AquaCal is produced by Marigot Ltd. The daily dose of 4 capsules of AquaCal provide 800mg calcium, (the EU RDA for calcium) and 74 mgs Magnesium (EU RDA 375mg). Subjects swallowed 4 capsules/day for six weeks.; AquaPT is produced by Marigot Ltd according to EU and FDA requirements. The daily dose of 4 capsules of AquaPT provides 720mg calcium, 200mgs green tea (polyphenols) and 50 mgs pine bark extract. Subjects swallowed 4 capsules/day for six weeks.; Subjects swallowed 4 capsules/day for six weeks.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary purpose: Treatment
Keywords: Bloating; Flatulence; Stomach discomfort