Health Effect of Energy Drink Consumption
Condition: Blood Pressure; Blood Glucose, High; Cognitive Change
Study type: Interventional

Summary: 
      Energy drinks consumption has varied effects on the hemodynamic, blood glucose levels, brain
      functions and memory. The use of energy drinks is pervasive and especially young adults
      consume it often as binge drinking. The negative health effects of excessive use of energy
      drinks has been reported in the scientific literature. Often energy drinks are consumed to
      enhance alertness and cognition improvement. In this trial, the investigators intend to
      compare the effects of a widely available energy drink brand in the country with the usual
      black tea with 5gm sugar and milk. The aims of this study is:

        1. To determine the effect of consumption of energy drinks on hemodynamics parameters.

        2. To determine the effect of consumption of energy drinks on short term memory

        3. To determine the effect of consumption of energy drinks on vigilance in adults

        4. To determine the effect of consumption of energy drinks on blood glucose in adults

        5. To analyze the effect of energy drink on perception in adults
    

Detailed description: 
      The participants will be halved in two groups: control group (consuming tea with 5gm of sugar
      only) and experimental group (consuming energy drinks only) to acquire data regarding
      fluctuations in hemodynamic parameters including heart rate (HR) and blood pressure
      (BP)-systolic and diastolic (SBP and DBP) by measuring them before and after 30 minutes of
      the consumption of tea with 5gm of sugar or energy drink in control or experimental groups.
      In addition blood glucose level will be monitored in both the groups via glucometer before
      and after. Reactions of energy drinks in comparison to tea on their respective groups will
      also be analyzed by help of a stroop test (where the name of the color itself does not match
      the ink of the color in which it is printed) for understanding its impact on cognitive
      strengths and on memory by a minor sequence learning game controlled by time lapse. After
      these interventions participants will be requested to fill out the questionnaire.

      The investigatorsare aiming for a sample size of 76 participants, 38 in each of the two
      groups.

      Data will be entered and analyzed in Statistical Package for the Social Sciences version 20
      or above. Mean and SD will be calculated for variables such as age, weight, blood pressure
      (Systolic and Diastolic) and heart rate, blood glucose and Stroop Test score. For qualitative
      variables such as sex, co morbidity e.g. heart disease, hypertension, family history will be
      presented as absolute frequencies and proportions. The hemodynamic parameters will be
      recorded before and after consumption of energy drinks in the intervention and the control
      group. Independent samples student t-test will be used to compare mean values of hemodynamic
      parameter between intervention and control group. Significance level of 5% will be set for
      the study keeping power at 80%.
    

Intervention name(s): energy drink
Intervention type(s): Other
Intervention description(s): An easily available 250 ml branded energy drink will be randomized to the partcipants after informed consent. Before and thirty minutes after drinking the given energy drink the participant cognition, heart rate, blood pressure and blood glucose will be measured.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Basic Science
Keywords: energy drink; hemodynamics; memory; stroop test