Comparison of the Effects of Different Nutrition Treatments on Patients With Irritable Bowel Syndrome
Condition: Irritable Bowel Syndrome
MeSH terms: Irritable Bowel Syndrome; Syndrome
Study type: Interventional

Summary: 
      Irritable Bowel Syndrome (IBS) is a disease associated with changes in bowel habits
      characterized by unexplained abdominal discomfort or pain. Common symptoms of the disease
      include gas, bloating, diarrhea, constipation, and common gastrointestinal problems
      associated with psychosocial problems. IBS makes it difficult for patients to attend school
      and work, reduce productivity, increase healthcare costs and negatively affect quality of
      life. Although IBS is not a life-threatening disease, it is a condition that must be tackled
      throughout life. The disease is clinically managed through dietary interventions and
      appropriate lifestyle changes, and pharmacological symptom-targeted or psychological
      treatments.

      The aim of this study is to determine the effects of different dietary treatment methods on
      patients 'severity symptom score and quality of life, and the patients' compliance with
      different dietary treatments.
    

Detailed description: 
      Patients between the ages of 19-65 who applied to Gaziantep University Faculty of Medicine,
      Department of Gastroenterology and diagnosed with Irritable Bowel Syndrome by the physician
      according to the Rome IV criteria will be included in the study. The aim of the study will be
      explained to the patients and the dietary treatment that will be recommended if they
      participate in the study will be told that they should be followed for 4 weeks. In addition,
      it will be notified that surveys will be conducted at the beginning and end of the 4-week
      period. Written consent will be obtained from individuals who agree to participate in the
      study.

      The minimum number of individuals in each group was determined to be 13 when the power was
      calculated as 80 at a 95% confidence interval. Individuals who accepted to participate in the
      study will be randomized into 4 different groups by minimization method according to age,
      gender, irritable bowel syndrome subtypes (diarrhea, constipation, mixed / undefined) and
      initial irritable bowel syndrome severity scores (mild, moderate, severe):. 1st Group:
      Traditional diet recommendations, 2nd Group: Low FODMAP diet, 3rd Group: Gluten-free diet,
      4th Group: Low-FODMAP gluten-free diet. When individuals are first enrolled in the study,
      they will be trained by the dietician for one hour before the medical nutrition treatment
      they will apply for 4 weeks.

      "Irritable Bowel Syndrome Severity Scoring Scale", "Bristol Stool Scale", "Irritable Bowel
      Syndrome Quality of Life Scale", "Food Consumption Frequency Survey including FODMAP Intake"
      and "Food Consumption Frequency Survey Including Gluten Intake" will be applied to
      individuals at the beginning of the study and at the end of the 4th week.
    

Intervention name(s): dietary treatment (low FODMAP); dietary treatment (gluten free); dietary treatment (low FODMAP+gluten free); dietary treatment (Traditional diet recommendations)
Intervention type(s): Other; Other; Other; Other
Intervention description(s): The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.; The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.; The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.; The aim of the study will be explained to the patients and the dietary treatment that will be recommended if they participate in the study will be told that they should be followed for 4 weeks. In addition, it will be notified that surveys will be conducted at the beginning and end of the 4-week period.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary purpose: Treatment
Keywords: low FODMAP; gluten free diet; irritable bowel syndrome