The Effect of Obesity on the Incidence of Postoperative Cognitive Dysfunction in Gynecological Day Case Surgery
Condition: Postoperative Cognitive Dysfunction
MeSH terms: Obesity; Postoperative Cognitive Complications; Cognitive Dysfunction
Study type: Interventional

Summary: 
      Cognitive dysfunction is the impairment of mental process of perception. memory and
      information processing which allow the human to acquire knowledge and plan for the future.
      The etiology of Post operative cognitive dysfunction (POCD) is unclear and seems to be
      multifactorial involving a combination of patient, surgical, anesthetic and environmental
      factors. The definition of day surgery in Great Britain and Ireland is clear; the patient is
      admitted and discharged on the same day.
    

Detailed description: 
      Cognitive dysfunction is the impairment of mental process of perception. memory and
      information processing which allow the human to acquire knowledge and plan for the future.
      The etiology of Post operative cognitive dysfunction (POCD) is unclear and seems to be
      multifactorial involving a combination of patient, surgical, anesthetic and environmental
      factors. It can be a manifestation of transient or permanent cerebral injury. While cognitive
      function tends to improve overmonths to years postoperatively in affected individuals, some
      proportion has seemingly permanent cognitive injury. Most of the studies of POCD, however,
      have methodological difficulties, as pointed out by Newman and colleagues in their review of
      more than 40 studies.

      The overweight/obese population has been steadily increasing worldwide. According to the WHO,
      with1.3 billion overweight (25 < body mass index [BMI] < 30) people and 600 million obese
      (BMI > 30) people in the world, the obesity rate exceeds10% for both genders and has more
      than doubled during the past 40 years. Furthermore, It considered as seven of the top10
      causes of death / physical disability and chronic disorders such as cancer and diabetes,
      which are closely related to obesity.

      The definition of day surgery in Great Britain and Ireland is clear; the patient is admitted
      and discharged on the same day, with day surgery as the intended management. The term '23-h
      stay' is used in the United states healthcare system. Obesity itself is not a
      contraindication to day surgery, as morbidly obese patients can be safely managed by experts,
      provided appropriate resources are available. This includes factoring in additional time for
      anaesthesia and surgery as well as the presence of skilled assistants and equipment.

      The incidence of complications during the operation or in the early recovery phase is greater
      in patients with increasing body mass index. However, these problems would still occur with
      inpatient care and have usually resolved or been successfully treated by the time a day-case
      patient would be discharged. In addition, obese patients benefit from short-duration
      anaesthetic techniques and early mobilisation associated with day surgery.

      Our study will aim to assess the early cognitive dysfunction after general anesthesia in
      normal weight patients, overweight and mild obese patients in gynacological day-case surgery.
    

Intervention name(s): Effect of Obesity on incidence of Postoperative cognitive in Gynecological Day- Day- case surgery
Intervention type(s): Behavioral
Intervention description(s): The effect of obesity on the incidence of postoperative cognitive dysfunction in Gynecological day-case surgery
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Investigator)
Primary purpose: Diagnostic
Keywords: Obesity; Day-case Surgery; Postoperative cognitive dysfunction