Assessment of Sleep Complaints in Brain Tumor Survivors
Condition: Brain Tumors
MeSH terms: Brain Neoplasms
Study type: Observational

Summary: 
      Survivors of pediatric brain tumors are noted to have increased rates of excessive daytime
      sleepiness. However, very little data are available regarding the specific sleep disturbances
      of pediatric brain tumor survivors. Children ages 8 to 18 years of age who are at least 5
      years from diagnosis and at least 2 years post treatment or observation only for a brain
      tumor will be targeted to assess the prevalence of sleep complaints.

      The study focuses on the following objectives:

        -  To estimate sleep disturbance in a cohort of pediatric brain tumor survivors.

        -  Estimate the rates of parent- and self-reported excessive daytime sleepiness in
           pediatric brain tumors

        -  Estimate the rates of parent-reported sleep-disordered breathing, including snoring and
           witnessed apneas, in pediatric brain tumor survivors

        -  Estimate the rates of parent- and self-reported behavioral sleep problems, including
           nocturnal enuresis, bedtime resistance, nighttime awakenings, nightmares, and fatigue in
           pediatric brain tumor survivors.

      The Study focuses on the following secondary objectives:

        -  To describe bedtime patterns and sleep hygiene of pediatric brain tumor survivors.

        -  Estimate the typical parent- and self-reported weekday sleep duration of pediatric brain
           tumor survivors

        -  Estimate the typical parent- and self-reported weekend sleep duration of pediatric brain
           tumor survivors and if it differs from the weekday sleep duration

        -  Estimate the typical parent- and self-reported consistency of sleep hygiene in pediatric
           brain tumor survivors
    

Detailed description: 
      This non-therapeutic single arm study will characterize the prevalence and types of sleep
      complaints of pediatric brain tumor survivors. Brain tumor survivors ages 8 to 18 years who
      are at least 5 years post diagnosis and 2 years post active therapy and their
      parents/guardians will be approached to participate during clinic visits. If the patient and
      guardian agree to participate, they will be administered three questionnaires in the clinic
      during the patient's visit. From the medical record, the following variables will be utilized
      to characterize the subjects and estimate which groups are at greatest risk of sleep
      disturbances:

        -  Specific brain tumor diagnosis

        -  Location of tumor (cerebral hemispheres, parasellar region, posterior fossa, or spine)

        -  Age at diagnosis

        -  Obesity status

        -  Treatment modality (surgery, radiation therapy, and/or chemotherapy vs. observation
           only)
    

Observational model: Cohort
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        Children ages 8 to 18 years of age who are patients at St Jude Children's Research Hospital
        and are at least 5 years from diagnosis and at least 2 years post treatment or observation
        only for a brain tumor were targeted to assess the prevalence of sleep complaints.
      
Keywords: Sleep complaints; Brain Tumor Survivors