Aerobic Physical Training and Heart Rate Variability in Hypertersion
Condition: Autonomic Nervous System Diseases
MeSH terms: Nervous System Diseases; Autonomic Nervous System Diseases; Primary Dysautonomias
Study type: Interventional

Summary: 
      This study compared the changes in the cardiovascular, hemodynamic and metabolic variables of
      hypertensive patients who received aerobic physical training with intensity determined by the
      protocol of double non-exhaustive efforts (DENE) with that of patients who received routine
      outpatient care 12 weeks after Entry into the study. 63 men and women participated in the
      study and were allocated in the intervention group (n = 42) and control group (n = 21).The
      following were performed: Cardiopulmonary exercise test (TECP) for evaluation of peak oxygen
      consumption (VO2peak), oxygen pulse and double product; DENE protocol for the determination
      of the intensity of the training. It was obtained the recording of the intervals between
      consecutive heart beats (iRR) to evaluate the autonomic modulation of the heart rate. Body
      mass index, waist circumference (AC), hip circumference (CQ) and Waist / hip ratio (WHR) were
      measured.
    

Detailed description: 
      The study was designed to compare changes in the cardiovascular, hemodynamic and metabolic
      variables of hypertensive patients who received aerobic physical training with intensity
      determined by the DENE protocol with that of patients who received routine ambulatory care 12
      weeks after entering the study.

      Sixty-three hypertensive men and women, divided into the intervention group (GI) (n=42) and
      the control group (n = 21) participated in the study.

      All procedures were performed by trained researchers and qualified staff and the evaluations
      and intervention were performed at the specialty medical outpatient clinic.

      After agreeing to participate in the study, we collected sociodemographic and clinical data,
      body mass index (BMI), waist circumference (WC) and waist / hip ratio (WHR). The participants
      were submitted to the cardiopulmonary exercise test (TECP), to evaluate the peak oxygen
      consumption (VO2peak), oxygen pulse and double product. Between one and seven days after
      TECP, consecutive heart rate intervals (iRR) were recorded for evaluation of autonomic heart
      rate modulation using a Polar model RS800CX (Polar Electro Co.Ltda Kempele, Finland). . The
      DENE protocol for determining the intensity of the training was applied in the GI to
      determine the training intensity in the treadmill. Intervention participants underwent
      supervised aerobic physical training at the pre-determined intensity, which consisted of
      three weekly sessions, lasting one hour, over a period of 12 weeks. Control participants
      receive routine care from the outpatient clinic for the same period. At the end of the 12
      weeks, measures, recording of the iRR intervals, oxygen pulse, double product, BMI, waist
      circumference (AC), hip circumference (QC) and waist / hip ratio (WHR) were obtained. All
      subjects were previously informed about the procedures Signed a free and informed consent
      form. The project was approved by the Commission of Research Committee of the Institution
      with the number 086.096 / 14.
    

Intervention name(s): Physical training program; Physical training program
Intervention type(s): Behavioral; Behavioral
Intervention description(s): Physical training program consisted of three weekly sessions lasting up to one hour over a period of twelve weeks. and will be carried out respecting the traditional training principles: biological individuality, Specificity, overload, adaptation and reversibility; All sessions were started with stretches for lower and upper limbs lasting 10 minutes for warm-up, and after trekking on treadmill using the predetermined critical velocity (Vcrit). The exercises were completed with cooling of the muscle groups for one minute still on the treadmill, plus 10 minutes of relaxation exercises on the mat at the end of aerobic exercise.
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: Exercisy therapy; Hypertension; Physiopathology; Heart rate; Nonlinear dynamics