Acute Effects of Juice Consumption With Biofunctional Compounds and Probiotics on Glucose Metabolism
Condition: Potential Abnormality of Glucose Tolerance; Appetite Disorders
MeSH terms: Feeding and Eating Disorders
Study type: Interventional

Summary: 
      This study investigated the short-term effects of fruit juice enriched with Vitamin D3 or n-3
      PUFA or probiotics and the combination of the three ingredients on glucose metabolism.
    

Detailed description: 
      This study aimed to 1. Determine the glycemic index and glycemic load of mixed fruit juice
      (pomegranate, grape, apple, and orange) enriched with Vitamin D3 or n-3 PUFA or probiotics,
      and the combination of the three bio-functional ingredients, compared to regular mixed fruit
      juice and the reference food (D-glucose), and 2.Examine the short-term effects of the five
      mixed fruit juices on postprandial blood glucose and salivary insulin responses, blood
      pressure, and subjective appetite, in healthy adults.
    

Intervention name(s): Glucose as reference food; Control juice; Juice with vitamin D3; Juice with n-3 fatty acids; Juice with probiotics; Juice with probiotics, vitamin D3, and n-3 fatty acids
Intervention type(s): Other; Other; Other; Other; Other; Other
Intervention description(s): Eleven healthy, normal body weight subjects after 10-14hr fast, consumed 50g glucose diluted in 300mL water, tested two times, in different visits, within 5-10 min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90, 120, 150 and 180 min. Salivary insulin samples were taken at baseline, 15, 30, 45, 60, 90, 120, and 180 min.; Eleven healthy, normal body weight subjects after 10-14hr fast, consumed 50g available carbohydrates from control juice (consisted of pomegranate, grape, apple and orange), tested once, within 5-10 min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90, 120, 150 and 180 min. Salivary insulin samples were taken at baseline, 15, 30, 45, 60, 90, 120, and 180 min.; Eleven healthy, normal body weight subjects after 10-14hr fast, consumed 50g available carbohydrates from juice (consisted of pomegranate, grape, apple and orange) containing vitamin D3, tested once, within 5-10 min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90, 120, 150 and 180 min. Salivary insulin samples were taken at baseline, 15, 30, 45, 60, 90, 120, and 180 min.; Eleven healthy, normal body weight subjects after 10-14hr fast, consumed 50g available carbohydrates from juice (consisted of pomegranate, grape, apple and orange) containing n-3 fatty acids, tested once, within 5-10 min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90, 120, 150 and 180 min. Salivary insulin samples were taken at baseline, 15, 30, 45, 60, 90, 120, and 180 min.; Eleven healthy, normal body weight subjects after 10-14hr fast, consumed 50g available carbohydrates from juice (consisted of pomegranate, grape, apple and orange) containing probiotics, tested once, within 5-10 min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90, 120, 150 and 180 min. Salivary insulin samples were taken at baseline, 15, 30, 45, 60, 90, 120, and 180 min.; Eleven healthy, normal body weight subjects after 10-14hr fast, consumed 50g available carbohydrates from juice (consisted of pomegranate, grape, apple and orange) containing probiotics, vitamin D3 and n-3 fatty acids, tested once, within 5-10 min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90, 120, 150 and 180 min. Salivary insulin samples were taken at baseline, 15, 30, 45, 60, 90, 120, and 180 min.
Other intervention name(s): reference drink D-Glucose; Vitamin D3; n-3 fatty acids; probiotics; probiotics, vitamin D-3, and n-3 fatty acids
Intervention MeSH terms: Vitamin D; Ergocalciferols; Cholecalciferol; Vitamins
Allocation: Randomized
Intervention model: Crossover Assignment
Intervention model description: Crossover assignment
Masking: Double (Participant, Investigator)
Primary purpose: Other
Keywords: blood glucose; insulin; glycemic index; glycemic load; juices; probiotics; vitamin D3; n-3 fatty acids