The Effect of Functional Bread Dadih on Microbiota Profile of Weight Increase Pregnant Women and Infant Birth Weight
Condition: Birth Weight; Pregnancy Weight Gain
MeSH terms: Body Weight; Birth Weight; Weight Gain; Gestational Weight Gain
Study type: Interventional

Summary: 
      The aims of study to determine the effect of giving functional bread and dadih's vla on
      weight gain of pregnant women and birth weight of babies.
    

Detailed description: 
      Dadih contains BAL 108 CFU/ml which is probiotic. Consumption of functional bread and dadih's
      vla during pregnancy can improve the composition of the gut microbiota so that it can
      increase maternal weight and provide adequate nutrition during pregnancy. Good nutrient
      absorption can support good nutritional status and weight in babies who are born. This study
      aims to determine the effect of giving functional bread and dadih's vla on weight gain of
      pregnant women and birth weight of babies.

      This study used a randomized controlled trial (RCT) design with a population of all pregnant
      women in the Kuranji, Nanggalo and Andalas Health Centers. The sample consisted of 88 people
      and was divided into two groups, namely the intervention group and the control group. Each
      amounted to 44 samples. The sample selection used the double-blind method and randomized
      controlled trial (RCT) research design. The intervention started at about 12-20 weeks of
      gestation and continued until just before the time of delivery. In the third trimester,
      subjects received healthy food, breastfeeding practices, and child development education to
      support mothers in maintaining their nutritional status, preparing exclusive breastfeeding,
      and optimizing child development.

      Healthy babies born to mothers will be the focus of this study and followed up until the age
      of three months to assess their growth. The information includes the baby's health history
      after birth, anthropometric measurements, nutritional intake, and breastfeeding practices
      which are measured repeatedly in the first, second, and third months.

      Data quality assurance is carried out through training starting from the period of data
      collection and supervision during and after data collection, including the data analysis
      process. This included training for enumerators, subjects and using a validated questionnaire
      for a group of subjects representing similar characteristics for this study. Data input and
      cleaning process will use excel and SPSS while for food intake data using NutriSurvey 2007.
      Data entry will be carried out by data collection officers after data collection. The data
      cleaning process includes removing outliers and regrouping multiple results that have similar
      meanings. The data will be interpreted as mean ± standard deviation if the data is normally
      distributed and the median (min-max) if the data is not normally distributed. Statistical
      analysis using SPSS 25 and data will be analyzed using univariate and bivariate analysis.
      Univariate analysis is used to describe characteristics and socio-demographics, medical
      history, pregnancy, and obstetric profiles of pregnant women. Numerical variables between
      groups will be analyzed using an Independent sample t-test if the data has normal
      distribution or the Mann Whitney test if the data distribution is not normal. Categorical
      variables between groups will be analyzed using Chi-square or Fisher test. Differences
      between birth and 3 months old follow up will be analyzed using independent t-tests if the
      data distribution has normal distribution or Mann Whitney test if the data distribution is
      not normal.
    

Intervention name(s): Bread and vla dadiah; Bread and vla without dadiah
Intervention type(s): Other; Other
Intervention description(s): Consumption bread and vla dadiah to pregnant women 1 Pieces a day during 12 weeks.; Consumption bread and vla without dadiah to pregnant women 1 Pieces a day during 12 weeks.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary purpose: Prevention
Keywords: Functional Bread; Weight Increase; Infant Weight