Aerobic and Strength Training With Caloric Restriction on Insulin Resistance in Obese Premenopausal Women
Condition: Insulin Resistance Syndrome
MeSH terms: Insulin Resistance; Metabolic Syndrome
Study type: Interventional

Summary: 
      A total of 42 premenopausal women diagnosed clinically as having insulin resistance. Their
      ages ranged from 35 to 45 years old; their body mass index was >30 kg/m2 and They were obese
      women complained of insulin resistance and non diabetic or cardiovascular disease, were
      randomly assigned to group A participated in aerobic & resistive exercise program, and group
      B participated in aerobic exercise and followed prescribed diet restriction program. Both of
      the groups (A&B) followed the treatment program 3 times per weeks for 8 weeks. Assessment of
      the fasting glucose, fasting insulin, and HOMA test of insulin resistance were measured for
      all subjects in both groups (A and B) was carried out before and after the end of the
      treatment program
    

Detailed description: 
      Forty two obese premenopausal women diagnosed as having insulin resistance were participated
      in this study. They were selected randomly from the out Patient Clinic of Obstetrics at Kasr
      El Ainy University Hospital, Faculty of Medicine, Cairo University. Their age ranged from 35
      - 45years, their body mass (BMI) were>30kg/m2. Exclusion criteria of the study were as
      follows: Patients having diabetic or cardiovascular disease, Patients with life threatening
      disorders as renal failure and myocardial infarction, Patients with active malignancy and
      patients with severe hemorrhage, hyperthyroidism, acute viral diseases and mental disorders.
      Participants were assigned randomly used sealed envelope into two groups (A&B) equally in
      number. Group (A): (Combined resistive and aerobic exercise group) consisted of 20 women were
      participated in aerobic & resistive exercise program plus diet restriction, 3 times per weeks
      for 8 weeks. Group (B): consisted of 20 women were participated in aerobic exercise plus diet
      restriction 3 times per weeks for 8 weeks.
    

Intervention name(s): Resistance exercise; Aerobic exercise; diet restriction
Intervention type(s): Other; Other; Dietary Supplement
Intervention description(s): Resistance exercise were performed for all participants in group (A) only included 9 exercise for big muscles of upper limbs (shoulder flexors muscles, shoulder extensors and shoulder abductors), lower limbs (hip flexors, hip extensors and knee flexors and knee extensors) and abdominal muscle using moderate work load (60 - 75% of IRM) 1set of 10 repetitions, progressing to 2 sets of 10 repetitions after four weeks for 20 minutes; aerobic exercise were performed on treadmill. For 20 minutes. All patients in both groups (A,B) had attended the program of a resistance exercises and followed by aerobic exercise for 8 weeks in form of 20 minutes walking on the treadmill without inclination.; All participants in both groups (A,B) were instructed to follow a moderate restricted diet limited to (1800-2000) kcal/ day under supervision of a certified dietician. The diet contained: Protein and fibers: 20% carbohydrate: 50-60%, fat: low 20%.
Other intervention name(s): exercise
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: were randomly assigned to group A participated in aerobic and resistive exercise program, and group B participated in aerobic exercise and followed prescribed diet restriction program. Both of the groups (A&B) followed the treatment program 3 times per weeks for 8 weeks. Assessment of the fasting glucose, fasting insulin, and HOMA test of insulin resistance were measured for all subjects in both groups (A and B) was carried out before and after the end of the treatment program.
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: resistive exercises; aerobic exercises; diet; insulin resistance; premenopausal