Impact of Nuun SPORT on Subjective Exercise Performance in Male and Female Runners
Condition: Hydration
Study type: Interventional

Summary: 
      The study will examine the impact of the Nuun Sport tablets, as compared to water only, on
      heart rate, perceived exertion, and related outcomes in male and female runners, during and
      following the performance of a 60-minute treadmill run.
    

Detailed description: 
      As discussed in our prior applications (protocol FY2020-327 and FY2021-96), maintaining
      adequate hydration is essential to optimal health (Perrier, 2017), as well as athletic
      performance (Nuccio et al., 2017). When individuals exercise (in particular in a warm
      environment), they can lose excessive amounts of fluids through sweating, along with
      necessary electrolytes (e.g., sodium, potassium, chloride). With dehydration, individuals may
      feel sluggish and can experience impaired physical performance. (Kenefick, 2018)

      Many attempts have been made to improve and measure the hydration status of active
      individuals (Love et al., 2018). This typically involves the ingestion of fluids leading up
      to activity (typically plain water), as well as the ingestion of fluids during the activity
      itself (water, along with a diluted carbohydrate/electrolyte beverage).

      During aerobic exercise, the shift in fluid (intake versus losses) can affect electrolyte
      balance, with dehydration and potential adverse effects on performance and health (Perrier et
      al., 2021; Armstrong et al. 2021). A better understanding of rehydration methods and
      resultant efficacy would permit selection by an athlete of the optimal method for preventing
      dehydration to optimize physical performance and reduce potential deleterious effects.

      It is well-accepted that electrolyte replenishment is of importance, both during and
      following exercise-to aid in rehydration for subsequent bouts. Electrolytes (sodium in
      particular) have been used for decades to aid athlete hydration and this has led to the
      development of various sport drinks-which also include small amounts of carbohydrate (e.g.,
      Gatorade, Powerade).

      The present study will examine the impact of the Nuun Sport tablets, as compared to water
      only, on heart rate, perceived exertion, and related outcomes: changes in body mass, changes
      in plasma volume, post-exercise urine volume, and changes in urine specific gravity in male
      and female runners, during and/or following the performance of a 60-minute treadmill run.
    

Intervention name(s): Nuun Sport Drink; Control
Intervention type(s): Dietary Supplement; Dietary Supplement
Intervention description(s): Subjects will consume a total of 24 ounces water and 1.5 tablets of Nuun SPORT. Specifically, subjects will drink 12 ounces of Nuun drink 15 minutes prior to the 60 min run and 4 ounces of Nuun drink at 15 min, 30 min, and 45 min during the run.; Subjects will consume a total of 24 ounces water. Specifically, subjects will drink 12 ounces of water 15 minutes prior to the 60 min run and 4 ounces of water at 15 min, 30 min, and 45 min during the run.
Allocation: Randomized
Intervention model: Crossover Assignment
Intervention model description: randomized, cross-over trial with water control.
Masking: None (Open Label)
Primary purpose: Basic Science
Keywords: Electrolyte; Running; Nuun