Therapeutic Exercise in Cancer-Related Fatigue in Women After Breast Cancer Treatment
Condition: Fatigue; Breast Cancer
MeSH terms: Breast Neoplasms; Fatigue
Study type: Interventional

Summary: 
      The main objective of this study is to determine whether the proposed program of therapeutic
      exercise is effective in improving fatigue, more than the exercise unsupervised depending on
      their preferences, in women treated for breast cancer.
    

Detailed description: 
      Introduction: The prevalence of cancer-related fatigue in women treated for breast cancer is
      about 30% having significant effects in reducing their quality of life. There is evidence of
      the presence of sleep problems and immune response. Several studies claim that physical
      exercise is effective during and after treatment of the disease as it improves the quality of
      life, cardiorespiratory function, physical functioning and symptoms of fatigue although not
      always found significant differences between intervention groups exercises compared with a
      control group. Although the results of these studies are promising, generally present
      methodological biases as small sample size, absence of masking, heterogeneous groups, lack of
      monitoring short and long term and especially lack of specificity in relation to prescribed
      exercise ( frequency, intensity, time and type of exercise).

      Subjects and methods: A randomized clinical trial, the examiner being blinded unaware of the
      intervention group to which subjects were assigned. Participants will be randomly assigned to
      two groups:

      An experimental group, where the participants will be treated with Therapeutic Exercise;

      And a group where will be done Physical Exercise according their preferences.

      Pre-intervention, immediate post-intervention, 3 and 6 months assessments will be made. The
      selection criteria will be: Adult women treated for breast cancer, completed at least 6
      months before, with persistent fatigue. All participants must understand and sign freely
      Informed Consent.

      Sample size: 40 women for each group.

      Data Analysis: A descriptive analysis of all variables was performed. It establish for all
      cases a confidence level of 95% (p <0.05). The effectiveness was assessed by comparing the
      experienced change of the two groups in outcome variables between physical therapy
      examinations.
    

Intervention name(s): Physical Exercise; Therapeutic Education; Therapeutic exercise-Physiotherapy
Intervention type(s): Other; Behavioral; Other
Intervention description(s): The patients were instructed to perform autonomous physical exercise program based preferences (progressive march on flat ground, dancing, cycling, etc.). They will receive written information. The program is 9 weeks with a frequency of 3 days per week and sessions about 50 minutes long.; Individual Therapeutic Education about healthy habits and exercise on breast cancer.; Cardiovascular exercise
Individualized progressive strength and resistance exercises of principals muscle groups of the lower limbs, upper limbs and trunk.
Flexibilization exercises
Other intervention name(s): Exercise; Hygienic and behavioral advises; Physiotherapy exercise
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: Physical Therapy Modalities; Breast Cancer Treatment; Exercise Therapy; Dyspnea