A Retrospective Analysis of Neck Dissection Following Complete Response to Chemoradiation in HNSCC
Condition: Head and Neck Cancer
MeSH terms: Head and Neck Neoplasms
Study type: Observational

Summary: 
      RATIONALE: Gathering disease-related information from medical charts of patients with primary
      head and neck cancer who have undergone neck dissection after complete response to
      chemotherapy and radiation therapy may help doctors learn more about the disease and find
      better methods of treatment.

      PURPOSE: This clinical trial is evaluating the medical charts of patients with primary head
      and neck cancer who have undergone neck dissection after complete response to chemotherapy
      and radiation therapy.
    

Detailed description: 
      OBJECTIVES:

        -  Perform a retrospective analysis, by medical chart review, of patients with primary
           squamous cell carcinoma of the head and neck who underwent neck dissection following
           complete response to chemoradiotherapy.

        -  Determine whether the role of a post-chemoradiotherapy neck dissection affects the
           outcome of the patient's disease, in terms of overall survival, disease-free survival,
           and recurrence rates.

      OUTLINE: This is a pilot, retrospective study.

      Patients who have undergone neck dissection after achieving a complete clinical and
      radiological response to chemoradiotherapy are compared to patients who did not. Data are
      gathered by medical chart review.
    

Intervention name(s): medical chart review
Intervention type(s): Other
Intervention description(s): medical chart review
Observational model: Case-Control
Time perspective: Retrospective
Sampling method: Non-Probability Sample
Study population: 
        Adults with the diagnosis of primary squamous cell carcinoma of the head and neck at any of
        the following sites:

          -  Oral cavity

          -  Oropharynx

          -  Hypopharynx

          -  Larynx
      
Keywords: stage I squamous cell carcinoma of the hypopharynx; stage II squamous cell carcinoma of the hypopharynx; stage III squamous cell carcinoma of the hypopharynx; stage IV squamous cell carcinoma of the hypopharynx; stage I squamous cell carcinoma of the larynx; stage II squamous cell carcinoma of the larynx; stage III squamous cell carcinoma of the larynx; stage IV squamous cell carcinoma of the larynx; stage I squamous cell carcinoma of the lip and oral cavity; stage II squamous cell carcinoma of the lip and oral cavity; stage III squamous cell carcinoma of the lip and oral cavity; stage IV squamous cell carcinoma of the lip and oral cavity; stage I squamous cell carcinoma of the oropharynx; stage II squamous cell carcinoma of the oropharynx; stage III squamous cell carcinoma of the oropharynx; stage IV squamous cell carcinoma of the oropharynx; stage I verrucous carcinoma of the larynx; stage II verrucous carcinoma of the larynx; stage III verrucous carcinoma of the larynx; stage IV verrucous carcinoma of the larynx; stage I verrucous carcinoma of the oral cavity; stage II verrucous carcinoma of the oral cavity; stage III verrucous carcinoma of the oral cavity; stage IV verrucous carcinoma of the oral cavity