Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones
Condition: Renal Stone
MeSH terms: Kidney Calculi; Nephrolithiasis
Study type: Interventional

Summary: 
      We want to compare the effect of lignocaine 2 % gel, Naproxen sodium and their combination on
      the pain control during extracorporial shock wave lithotripsy for renal stones.
    

Detailed description: 
      Introduction of ESWL (extracorporeal shock wave lithotripsy) has revolutionized the treatment
      of urolithiasis due to its noninvasive in nature, cost effectiveness, reduced hospitalization
      time and less morbidity1, 2.Impact of shock waves cause pain in most of the patient requiring
      analgesia or sedation. It is important to make patient pain free to get the maximum possible
      stone free rates3, 4. Opioids are used most commonly for pain relief in ESWL but with side
      effects requiring patient monitoring and delayed hospital stay3, 4. NSAIDS also showed
      promising results regarding pain control in ESWL without side effects of opoids1, 5. Local
      analgesia gels have controversial role in relieving pain in ESWL 1, 6. There are yet no
      guidelines for pain relief during ESWL1, 4. We intend to compare the effect of local
      analgesia gel, oral NSAIDS and their combination on pain during lithotripsy.
    

Intervention name(s): Lidocaine gel,; Naproxen Sodium; Lidocaine gel and Naproxen Sodium
Intervention type(s): Drug; Drug; Drug
Intervention description(s): 2% lidocain gel will be applied to coresponding lumber area 30 minutes before ESWL for renal stones. Maximum of 4000 shock waves will be delivered. Rescue analgesia will be given as intravenous nalbuphine if patient demanded. Pain score is measured with visual analogue pain score from 1 to 10 after completion of procedure if patient donot needed rescue analgesia and during procedure just before giving rescue analgesia in those who demanded it.; Tab Naproxen sadium 550 mg per oral will be given to patients 30 minutes before ESWL for renal stones. Maximum of 4000 shock waves will be delivered. Rescue analgesia will be given as intravenous nalbuphine if patient demanded. Pain score is measured with visual analogue pain score from 1 to 10 after completion of procedure if patient donot needed rescue analgesia and during procedure just before giving rescue analgesia in those who demanded it.; Tab Naproxen sodium 550 mg per oral will be given to patients 45 minutes before ESWL and 2% lidocain gel will be applied to coresponding lumber area 30 minutes before ESWL for renal stones. Maximum of 4000 shock waves will be delivered. Rescue analgesia will be given as intravenous nalbuphine if patient demanded. Pain score is measured with visual analogue pain score from 1 to 10 after completion of procedure if patient donot needed rescue analgesia and during procedure just before giving rescue analgesia in those who demanded it.
Other intervention name(s): Lignicaine; NSAIDS; NSAIDS and Lidocaine
Intervention MeSH terms: Naproxen; Anti-Inflammatory Agents, Non-Steroidal; Lidocaine
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Double (Participant, Care Provider)
Primary purpose: Treatment
Keywords: Lidocaine gel; Extracorporeal shockwave lithotripsy; Naproxen sodium; Pain score