Efficacy of Amygdala Retraining With Mindfulness (ART+MF) vs Compassion Therapy (CT) for the Treatment of Patients With Fibromyalgia
Condition: Fibromyalgia
MeSH terms: Fibromyalgia; Myofascial Pain Syndromes
Study type: Interventional

Summary: 
      Amygdala Retraining Treatment (ART) is a new and promising therapy for patients with Chronic
      Fatigue Syndrome (CFS) and Fibromyalgia (FM), however, randomized controlled trials (RCT) are
      scarce. The investigators have added mindfulness to this therapy, based on preliminary
      reports of its efficacy on patients, obtaining Amygdala Retraining Treatment with Mindfulness
      (ART+MF).

      Other therapy that has been assessed in many psychiatric and medical disorders during the
      last years has been Compassion Therapy (CT). There are no studies on its efficacy in FM.

      Aims: The aim of this trial is to assess the efficacy of both ART+MF and CT on the general
      function of the patients with FM. A secondary objective is to assess the effect of these
      therapies on psychological (pain, depression, anxiety, etc.) and biological variables (some
      biomarkers related with inflammation).

      Methods:

        -  Design: Randomized, controlled trial with three arms: a) ART+MF, b) CT and c) Relaxation
           as control intervention.

        -  Sample: A sample (N=60 patients, about N=20 for each arm) will be recruited from primary
           care settings at the city of Zaragoza, Spain.
    


Intervention name(s): ART with Mindfulness; Mindfulness Compassion; Relaxation
Intervention type(s): Behavioral; Behavioral; Behavioral
Intervention description(s): Introduction of ART with Mindfulness. Visualization of 100% recovery
Developing Fibromyalgia and CFS. How stress triggers the central nervous system. The benefits of Mindfulness in chronic stress. Mindfulness Practice. Breathing meditation
The ART. Breaking the negative thoughts related to the illness. Walking meditation
Mindfulness and the Body Scan. Breaking the cycle of stress. Body-scan meditation
Mindfulness and self-compassion. Kindly awareness meditation
The accelerator of ART. Behaviors related to CFS and Fibromyalgia. Metta meditation
Aware of negative thoughts related to stress stimulus. Mindfulness in daily activities
Limiting beliefs, identity patterns. Motivation and sense of life. Meditation on values
The recovery, cycles and stages. Fear of fail about recovery. Positive Visualization of future self
Return to regular life. Mindfulness practice; Introduction.Definition of Compassion
Self-Esteemed and Compassion
Cultivate the understanding of the nature of inner experience. Working positive and negative thoughts.Connecting with difficult emotions
Identifying the causes of suffering.How participants contribute to their own suffering. Attachments.Practice of Vulnerability
Love,affection and self-compassion.How participants connect with the suffering of others
Equanimity
Forgiveness
Interdependence. Gratitude.Affection to unknown people
Developing affection and empathy.Empathy and burn out
Review of the practices and meditations; 10 sessions based on relaxation techniques as active comparator intervention
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary purpose: Treatment