Female Sexual Function After Cystectomy
Condition: Sexual Activity
Study type: Observational

Summary: 
      Cystectomy with bladder replacement, with or without urinary diversion, is the preferred
      treatment option for benign pathologies responsible for neurogenic bladder or sphincter
      dysfunction after failure of conservative treatments.

      This surgery has both the objective of preventing urological complications and improving
      quality of life.

      We know that women are especially affected by these conditions, as demonstrated by the high
      prevalence of demyelinating diseases such as multiple sclerosis in this population. Patients
      are often young and sexually active before the surgery.

      Despite the existence of validated evaluation tools since the early nineties, there is poor
      data exploring effects of invasive procedures such as cystectomy on sexual activity and
      quality of sexual life in female patients.

      Indeed, existing literature largely focuses on sexual function in male population after
      cystectomy for urothelial cancer.

      Data on sexual function after stoma formation in women with colorectal cancer show a
      significant change after the surgery, partly due to body image issues. We can easily suppose
      that there's also an important impact of cystectomy that may affect sexual quality of life.

      Thus, the objective of the study is to assess sexual function and determine factors that may
      influence sexual quality of life in female patients following cystectomy or urinary
      diversion.
    


Intervention name(s): Questionnaires
Intervention type(s): Other
Intervention description(s): Four Questionnaires in French will be sent to participants :
1 questionnaire about sexual and urinary symptoms before and after the surgery ;
1 validated questionnaire "Female Sexual Function Index" to assess sexual function over the past 4 weeks ;
1 validated questionnaire "Body Image Scale" to assess body image during the past week ;
1 validated questionnaire "Stoma Quality of Life", only for patients with incontinent urostomy.
If the questionnaires are not returned 15 days after sending, a follow-up phone call will be made by one of the investigators.
The data collection will include both the answers to the questionnaires and the patients' computerized medical data:
Pathology responsible for the urological disorders and date of onset of the disorders
Date and Type of surgery performed
Patient's age at the time of surgery
Post-operative complications within one month of surgery
Observational model: Case-Only
Time perspective: Other
Sampling method: Non-Probability Sample
Study population: 
        The study population consists in alive female patients aged 18-75 years, who undergone a
        partial or total cystectomy and/or urinary diversion and/or urinary ostomy repair
        operations between 01/01/2007 and 15/12/2019 at the "Lyon Sud" Hospital and able to
        complete the questionnaires.

        All patients suffer from urological disorders caused by a non-malignant pathology, and have
        had surgery after failure of conservative therapies.

        Among the patients identified from the computerized medical records, 55 suffer from
        Multiple sclerosis, 29 patients from Spinal Cord Injury, 21 suffer from Suprapontine and
        pontine lesion or disease, 19 suffer from non-traumatic lesion or disease between caudal
        brainstem and sacral spinal cord,18 suffer from lesions of the peripheral nervous system, 8
        suffer from interstitial cystitis or idiopathic disorders and 1 suffers from a
        neurodegenerative disease of unknown etiology