Rapid Screening Circuit of COVID 19 in Schools, Pilot Study
Condition: SARS-CoV-2 (COVID-19)
MeSH terms: COVID-19
Study type: Interventional

Summary: 
      The outbreak of coronavirus disease 2019 (COVID-19), caused by acute respiratory syndrome
      severe coronavirus 2 (SARS-CoV-2), emerged in Wuhan in December 2019 and has spread which
      poses a serious threat to public health. While 80% of the patients are asymptomatic or have a
      mild illness, 20% develop a serious illness. Predominant symptoms include fever, cough, and
      myalgias.

      Most children have one mild or asymptomatic disease that can be resolved without medical
      attention and that, exceptionally, may progress to pneumonia and respiratory failure
      requiring hospitalization

      Schools have started the course with strict protocols to prevent the transmission of
      SARS-Cov-2 among the members of the educational communities and thus avoid an
      uncontrollability of the epidemic. These protocols include scaled entrances in the centers
      and differentiated circulation to optimize compliance with social distance. They also include
      the creation of coexistence groups, the Ventilation of the spaces, hand washing, disinfection
      of furniture, and wearing a face mask. One key point in the prevention of infection is the
      rapid detection of infected individuals, their isolation immediate and quarantine, and
      screening of coexistence groups of positive cases. The diagnosis of Suspicious cases from
      both schools and other settings is done with a PCR, mostly in Primary Care Centers (PCC).
      This is causing an increased considerable volume of work for primary care centers.

      In addition to the overload of the PCCs, the waiting time between sampling and PCR means that
      the person must remain at home until the result is obtained, with the negative impact that
      this means on the daily lives of students, teachers, and families. The use of a quick test
      performed on the own schools and with staff from the center itself trained to do this first
      screening would have three very relevant consequences for the system:

        1. Speed up the diagnosis and minimize the waiting time between the presentation of
           symptoms and quarantine of the whole group (if positive)

        2. Avoid a waiting time at home with the alteration - often unnecessary - of the day of
           students, their families, and school staff.

        3. Decongest the PCCs, receiving only the cases that need confirmation
    

Detailed description: 
      The outbreak of coronavirus disease 2019 (COVID-19), caused by acute respiratory syndrome
      severe coronavirus 2 (SARS-CoV-2), emerged in Wuhan in December 2019 and has spread which
      poses a serious threat to public health. While 80% of the patients are asymptomatic or have a
      mild illness, 20% develop a serious illness. Predominant symptoms include fever, cough, and
      myalgias.

      Most children have one mild or asymptomatic disease that can be resolved without medical
      attention and that, exceptionally, may progress to pneumonia and respiratory failure
      requiring hospitalization

      Schools have started the course with strict protocols to prevent the transmission of
      SARS-Cov-2 among the members of the educational communities and thus avoid an
      uncontrollability of the epidemic. These protocols include scaled entrances in the centers
      and differentiated circulation to optimize compliance with social distance. They also include
      the creation of coexistence groups, the Ventilation of the spaces, hand washing, disinfection
      of furniture, and wearing a face mask. One key point in the prevention of infection is the
      rapid detection of infected individuals, their isolation immediate and quarantine, and
      screening of coexistence groups of positive cases. The diagnosis of Suspicious cases from
      both schools and other settings is done with a PCR, mostly in Primary Care Centers (PCC).
      This is causing an increased considerable volume of work for primary care centers.

      In addition to the overload of the PCCs, the waiting time between sampling and PCR means that
      the person must remain at home until the result is obtained, with the negative impact that
      this means on the daily lives of students, teachers, and families. The use of a quick test
      performed on the own schools and with staff from the center itself trained to do this first
      screening would have three very relevant consequences for the system:

        1. Speed up the diagnosis and minimize the waiting time between the presentation of
           symptoms and quarantine of the whole group (if positive)

        2. Avoid a waiting time at home with the alteration - often unnecessary - of the day of
           students, their families, and school staff.

        3. Decongest the PCCs, receiving only the cases that need confirmation
    

Intervention name(s): Escola L'Horitzó; Escola John Talabot
Intervention type(s): Other; Other
Intervention description(s): Diagnosis of SARS-CoV-2 infection by rapid antigen detection tests in nasal and nasopharyngeal swabs, in asymptomatic and symptomatic subjects who attend regularly to L'Horitzó school .; John Talabot School will provide the incidence of infection by SARS-CoV-2 in order to compare the incidence of infection from L'Horitzó School.
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Intervention model description: Experimental Group: People attending L'Horitzó School (students, teachers, administrative and service staff) Control Group (No Intervention): Escola John Talabot
Masking: None (Open Label)
Primary purpose: Prevention
Keywords: SARS-CoV-2; COVID-19; Coronavirus; School