Effects of Progressive Resistance Training Compared With Aerobic Training in Patients With Hemophilia
Condition: Quality of Life; Muscle Weakness
MeSH terms: Muscle Weakness; Hemophilia A
Study type: Interventional

Summary: 
      This study aims to assess the effects of progressive resistance training compared with
      aerobic training, among those with hemophilia. Participants will be divided into two groups.
      The control group will receive an aerobic exercise protocol, and the resistance group will
      follow a resistance training program. Each group will receive a total of eight sessions.
      Target muscles are deltoids, biceps, triceps, quadriceps, hamstrings, and calves.

      Subjective and objective assessment will be performed for each group, to determine the
      effectiveness of each intervention.
    

Detailed description: 
      Participant's height, weight and age will be recorded for pre-test anthropometric data.
      Height will be measured using a stadiometer, and weight will be measured with an electronic
      scale.

      Treatment sessions will be conducted twice a week, for 8 weeks. The control group will be
      administered a standard physical therapy intervention program which will consist of active
      muscle stretching and aerobic exercises.

      Exercises will include:

        -  Flexion, extension and abduction at the shoulder joint for anterior, middle and
           posterior fibers of deltoid

        -  Flexion and extension at the elbow for biceps and triceps trachii

        -  Flexion and extension at the knee joint for quadriceps and hamstring muscles

        -  Plantar flexion at the ankle joint for gastrocnemius and soleus Three sets of ten
           repetitions of each exercise will be done.

      The intervention group will undergo a progressive resistance training program consisting of
      active muscle stretching and resistance training. Exercise for intervention group will
      consist of:

        -  Resisted flexion, extension and abduction at the shoulder joint for anterior, middle and
           posterior deltoid, using dumbbells

        -  Resisted flexion and extension at the elbow for biceps and triceps trachii, using
           dumbbells

        -  Resisted flexion and extension of knee joint for quadriceps and hamstring muscles, using
           therabands

        -  Resisted dorsiflexion and plantar flexion of gastrocnemius and soleus, using therabands

      Resistance will be increased on basis of progressive overload principle. Three sets of ten
      repetitions will be performed per muscle group. Initial weight of the dumbbells will be 1kg
      and will be increased by 0.5kg per week. Therabands used will be Yellow, Red, Green and Blue.
      Resistance for therabands will be upgraded every two weeks. Treatment time per group will be
      approximately 40 minutes. Exercises will be progressed in a gradual manner to give
      participants time to build muscle strength.
    

Intervention name(s): Progressive resistance training; Aerobic training
Intervention type(s): Other; Other
Intervention description(s): Resistance training of upper limb and lower limb muscles. Resistance will be increased on a weekly basis. Dumbbells and therabands will be used to provide resistance.; The control group will be administered a standard physical therapy intervention program which will consist of active muscle stretching and aerobic exercises.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Health Services Research
Keywords: Hemophilia; resistance training; aerobic exercise; Pakistan