Rate of Torque Development in Adolescents With Osgood-Schlatter
Condition: Osgood-Schlatter Disease
MeSH terms: Osteochondrosis
Study type: Observational

Summary: 
      Osgood-Schlatter is a growth-related condition involving multiple different types of tissue
      in the tendon-bone interface at the tibial tubercle. Osgood-Schlatter affects one in ten
      adolescents causing persistent pain and reduced ability to maintain physical activities.
      Changes in rate of torque development is associated with decreased neuromuscular functioning
      and pain chronicity, thereby affecting athletic performances and general physical activities.
      However, changes in rate of torque development has not been investigate in patients with
      Osgood-Schlatter and could help characterize the condition and guide management.

      The aim of the study is to investigate early and peak rate of torque development during
      maximal voluntary isometric knee extension and knee flexion in adolescents with
      Osgood-Schlatter, compared to a matched group of asymptomatic adolescents (controls), in a
      cross-sectional study.

      The study will include 13 adolescent participants with Osgood-Schlatter and a group of 13
      pain free controls matched on sex, age, and sports participation on the group level. Testing
      will include rate of torque measurements of knee extension and flexion for each limb with a
      fixated handheld dynamometer during a single test-session lasting approximately two hours.
      The examiner responsible for strength-testing will be blinded to case-status. Along with
      anthropometric data, participants will perform the anterior knee pain provocation test to
      assess pain-response to sustained knee loading, a countermovement jump test to assess power
      and jump height, and provide patient-reported measures of condition severity, pain,
      disability, and quality of life. Data collection will start March 2023 and is expected to
      finish by May 2023.
    


Intervention name(s): Rate of torque development testing of knee flexors and knee extensors using a fixated handheld dynamometer (MicroFet 2, Hoggan, Scientific L.L.C., Salt Lake City, USA), sampling rate of 100hz)
Intervention type(s): Other
Intervention description(s): Participants and their parents/guardian receives information about the test procedures. Written informed consent is obtained before clinical examination and testing.
Clinical testing is performed, anthropometric values are obtained and patient reported outcome measure is filled out, before the tests are performed. Cases will receive treatment for their condition and controls a movie ticket as compensation.
Observational model: Case-Control
Time perspective: Cross-Sectional
Sampling method: Non-Probability Sample
Study population: 
        Adolescents aged 9-16 residing in the uptake area of Copenhagen University Hospital,
        Amager-Hviodvre (1.8m total residents), who is made aware of the study be either 1) being
        referred to the orthopedic department for Osgood-Schlatter, 2) sees adverts and local
        sports clubs, or 3) sees the online advert on the research unit webpage
      
Keywords: Adolescents; Rate of torque development; Osgood-Schlatter; Neuromuscular; Inhibition