Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
Condition: Surgical Site Infection
MeSH terms: Surgical Wound Infection
Study type: Interventional

Summary: 
      We are investigating outcome of antibiotic coated vicryl versus non coated vicryl in terms of
      rate of surgical site infection and lebgth of hospital stay in children after lalaprotomy for
      perforated viscera. total 100 patients will be taken and 50 in each group.
    

Detailed description: 
      Pneumoperitoneum is typically a surgical emergency, particularly in children and more than
      90% of occurrences are caused by perforation of the gastrointestinal tract and other hollow
      viscera. Wound infections after abdominal surgery are still frequent types of nosocomial
      infections. Sutures can be a source of wound infection and dehisence due to bacterial
      adherence and colonization. Sutures coated with antibacterial agents have been developed in
      an attempt to reduce bacterial adherence and colonization of suture materials. The objective
      of the study is to compare the outcome of antibiotic coated vicryl versus non-coated vicryl
      in abdominal fascial closure after laparotomy in children in regards of surgical site
      infections. It will be a randomized controlled trial in which 100 patients admitted in
      Children Hospital Lahore will be included. Simple random sampling will be carried out.
      Informed written consent will be taken from patients' guardian. The patients will be divided
      into two groups (50 in each group). Group-A patients will undergo laparotomy closure with
      antibiotic coated vicryl while Group-B patient will experience non-coated vicryl in abdominal
      fascial closure. All patients will be examined on 3rd, 7th and 30th post-operative day for
      wound infection according to Southampton wound scoring system. Data will be collected through
      predesigned proforma, which will be entered and statistically analyzed using SPSS version
      24.0. For quantitative variables mean and standard deviation will be calculated and for
      qualitative variables frequency and percentages will be calculated. Data will be presented in
      tables and graphs. Chi-square test will be used to estimate the association between
      qualitative variables. P-value <0.05 will be considered significant. It is expected that
      results of this study may be helpful for healthcare providers to provide appropriate
      treatment to the patients and to prevent them from wound related complications.
    

Intervention name(s): antibiotic coated vicryl used for fascial closure
Intervention type(s): Procedure
Intervention description(s): in this group fascial closure was done with antibiotic coated vicryl to compare with non coated vicryl after lapaprotomy in contaminated wounds
Intervention MeSH terms: Anti-Bacterial Agents
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Other
Keywords: SSIs, anti biotic coated vicryl, laparotomy, Triclosan coated vicryl, Vicryl plus, Surgical site infection, Uncoated vicryl,