Refining Novel Culturally Tailored Behavioral Weight Loss Treatment Components for Sexual Minority Women With Obesity
Condition: Obesity
MeSH terms: Obesity; Weight Loss
Study type: Interventional

Summary: 
      Obesity disproportionately impacts sexual minority women. Behavioral weight loss programs are
      the gold standard treatment for mild to moderate obesity. The investigators have developed an
      online behavioral weight loss program that is effective, low-cost, and highly scalable.
      However, existing research suggests that tailoring treatment to address 3 well-established
      weight loss barriers in sexual minority women will be critical for maximizing the relevance
      and efficacy of behavioral weight loss for this group. The goal of the first phase of this
      K23 is to develop 3 novel treatment components targeting sexual minority women's weight loss
      barriers (i.e., minority stress, low social support, and negative body image), to pilot the
      program in sexual minority women with overweight/obesity, and to conduct individual
      qualitative interviews to elicit feedback on the intervention's acceptability, cultural
      relevance, usability, and feasibility that will be used to refine the program. After a
      pre-piloting phase (consisting of initial content piloting, interviews, and intervention
      refinement; anticipated n=12), 8 participants will pilot the full 3-month weight loss program
      and will be randomized to pilot 0-3 novel tailored components (targeting minority stress,
      negative body image, and social support) over the 3-month period. Participants will complete
      quantitative and qualitative assessments of intervention acceptability and appropriateness
      post-treatment and the intervention will be refined.
    


Intervention name(s): Behavioral Weight Loss Intervention; Minority Stress Intervention; Negative Body Image Intervention; Social Support Intervention
Intervention type(s): Behavioral; Behavioral; Behavioral; Behavioral
Intervention description(s): Rx Weight Loss: PRIDE is a fully automated online behavioral obesity treatment that is tailored for sexual minority women and involves viewing 12 online video lessons delivered each week, self-monitoring body weight, calorie intake, and physical activity levels, and receiving personalized automated weekly feedback on progress toward goals.; The Minority Stress Intervention is designed to help sexual minority women cope with stress and stigma (e.g., due to weight, sexual orientation, gender). In this program, participants watch online video lessons that teach cognitive and behavioral strategies for coping with minority stress so that it may have less of an influence on participants' weight and well-being.; The Negative Body Image Intervention is designed to help participants improve their body image. In this program, participants will watch online video lessons that provide education on queer women's body image and teach cognitive and behavioral strategies for improving your body image (regardless of your weight) to reduce its influence on your health.; The Social Support Intervention provides online opportunities for participants to receive more social support as they work toward their weight loss goals. Participants receive education on the importance of social support for weight management, they can earn badges for completing program milestones, and they gain access to a private online forum to get support and advice from other participants.
Other intervention name(s): Coping with Stress Program; Body Image Program
Allocation: Randomized
Intervention model: Factorial Assignment
Intervention model description: After a pre-piloting phase (consisting of initial content piloting, interviews, and intervention refinement; anticipated n=12), participants (anticipated n=8) will receive the online weight loss treatment and will be randomized to receive 0-3 novel intervention components (targeting minority stress, negative body image, and social support) over the 3-month period. Participants will complete quantitative and qualitative assessments of intervention acceptability and appropriateness post-treatment.
Enrollment for both the pre-piloting phases (anticipated n=12) and open pilot trial phase (anticipated n=8) are reported here.
Masking: None (Open Label)
Primary purpose: Other
Keywords: Sexual minority women; LGBTQ health; Weight loss