Effect of Oxyflower® Gel as a Coadjuvant in Pericoronitis Treatment
Condition: Pericoronitis
MeSH terms: Pericoronitis
Study type: Interventional

Summary: 
      The objective of this study is to evaluate the clinical effect and the impact on the quality
      of life of the coadjuvant treatment with Oxyflower® gel in cases of pericoronitis in lower
      third molar, compared to chlorhexidine gel and placebo gel.
    

Detailed description: 
      This study consist of 51 participants diagnosed with pericoronitis who received coadjuvant
      treatment with gel. The participants were submitted to emergency treatment, with local
      debridement and irrigation with saline solution followed by topical application of the
      randomized gel: oxyflower®, chlorhexidine, or placebo gel. In cases of pericoronitis with
      systemic signs / symptoms, such as fever, malaise and lymphadenopathy, systemic antibiotic
      therapy was prescribed one hour before debridement, lasting seven days. All participants
      received oral hygiene guidelines and were instructed to apply the same gel twice daily for
      one week . After 30 days, it was performed tooth removal for cases in which there is not
      enough space for dental eruption; or distal wedge surgery when there is space for dental
      eruption with excessive gingiva in the distal. It was evaluated as outcomes: pain, quality of
      life, depth of probing, level of bone crest in the distal of second molar, buccal opening and
      extent of edema / erythema. A comparative analysis was performed between the groups, before
      and after treatment.
    

Intervention name(s): OxyFlower gel; Chlorhexidine gel; Placebo gel
Intervention type(s): Other; Other; Other
Intervention description(s): the region with pericoronitis was debrided using gauze and curettes, with copious irrigation with sterile saline solution. At this moment, the gel was applied topically under the pericoronal hood, with a standard volume of 2microIiters, using a dosing syringe. Then, participants received instructions on oral hygiene and how to use the gel at home, twice a day for one week. After 30 days, it was performed third molar removal or distal wedge removal; the region with pericoronitis was debrided using gauze and curettes, with copious irrigation with sterile saline solution. At this moment, the gel was applied topically under the pericoronal hood, with a standard volume of 2microIiters, using a dosing syringe. Then, participants received instructions on oral hygiene and how to use the gel at home, twice a day for one week. After 30 days, it was performed third molar removal or distal wedge removal.; the region with pericoronitis was debrided using gauze and curettes, with copious irrigation with sterile saline solution. At this moment, the gel was applied topically under the pericoronal hood, with a standard volume of 2microIiters, using a dosing syringe. Then, participants received instructions on oral hygiene and how to use the gel at home, twice a day for one week. After 30 days, it was performed third molar removal or distal wedge removal
Intervention MeSH terms: Chlorhexidine
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary purpose: Treatment
Keywords: Quality of life; Pericoronitis; Phytotherapy