Percutaneous Ultrasound-guided "Three-step" Radiofrequency Ablation for Giant Hepatic Hemangioma
Condition: Hepatic Hemangioma
MeSH terms: Hemangioma
Study type: Interventional

Summary: 
      Hepatic hemangioma is the most common benign tumor of the liver.For huge liver hemangioma,
      however, it need to use the conventional radiofrequency ablation can increase one-time
      ablation volume of radiofrequency electrode or enhance ablation power and extend the melting
      time, not only bring patients suffering discomfort, but easy to damage the adjacent organs,
      causing serious complications such as hemorrhage, perforation of gastrointestinal tract,acute
      renal failure .Therefore, the investigators have developed a new, standardized radiofrequency
      ablation for giant hepatic hemangioma to shorten the duration of treatment, reduce surgical
      complications and improve the surgical success rate.

      The purpose of this study was to evaluate the safety, feasibility and efficacy of the new
      radiofrequency ablation (" three-step "radiofrequency ablation) in the treatment of giant
      hepatic hemangioma.
    

Detailed description: 
      Hepatic hemangioma is the most common benign tumor of the liver, with an incidence of 0.4-20%
      in the general population.For small and asymptomatic patients with hepatic hemangioma,
      regular reexamination is necessary without medical intervention.However, patients with giant
      hepatic hemangioma(diameter ≥ 5cm) may have symptoms such as abdominal pain, indigestion,
      jaundice, or rapid increase in lesion volume, or even spontaneous rupture and hemorrhage,
      which require active treatment.Currently, surgical resection is the most effective method for
      the treatment of hepatic hemangioma, but the incidence and mortality of related complications
      have been reported as high as 27% and 3% respectively

      .Other alternative therapies, such as transcatheter arterial embolization, radiotherapy and
      steroid therapy, have also been reported for the treatment of hepatic hemangioma, but the
      efficacy is not satisfactory .

      Percutaneous ultrasound-guided radiofrequency ablation is a safe and minimally invasive
      treatment with reliable efficacy. In recent years, this technique has been successfully
      applied in the treatment of hepatic hemangioma with a diameter of < 5cm.For huge liver
      hemangioma, however, need to use the conventional radiofrequency ablation can increase
      one-time ablation volume of radiofrequency electrode or enhance ablation power and extend the
      melting time, not only bring patients suffering discomfort, but easy to damage the adjacent
      organs, causing serious complications such as hemorrhage, perforation of gastrointestinal
      tract, acute renal failure .Therefore, the investigators have developed a new,standardized
      radiofrequency ablation for giant hepatic hemangioma to shorten the duration of treatment,
      reduce surgical complications and improve the surgical success rate.

      The purpose of this study was to evaluate the safety, feasibility and efficacy of the new
      radiofrequency ablation (" three-step "radiofrequency ablation) in the treatment of giant
      hepatic hemangioma.
    

Intervention name(s): "three-step" radiofrequency ablation; radiofrequency ablation
Intervention type(s): Procedure; Procedure
Intervention description(s): After destroying the main blood supply of the tumor, extracting the blood in the tumor, reducing the blood flow in the tumor and shrinking the tumor volume, the remaining tumor was then treated with radiofrequency ablation, namely the "three-step" radiofrequency ablation with "one block, two inhalation and three damages".; Conventional radiofrequency ablation
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Treatment