Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer
Condition: Breast Cancer; Cognitive/Functional Effects; Colorectal Cancer; Lung Cancer; Pain; Prostate Cancer; Psychosocial Effects of Cancer and Its Treatment
MeSH terms: Breast Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms
Study type: Observational

Summary: 
      RATIONALE: Questionnaires that assess symptoms caused by cancer and cancer therapy may help
      improve the ability to plan treatment for patients with invasive cancer to help them live
      longer and more comfortably.

      PURPOSE: This clinical trial is studying symptoms caused by cancer and cancer therapy in
      patients with invasive breast, lung, prostate, or colorectal cancer.
    

Detailed description: 
      OBJECTIVES:

      Primary

        -  Determine the prevalence, severity, and interference due to physical and psychological
           symptoms experienced (over a 4 to 5 week period) by patients with invasive primary
           breast, lung, prostate, or colorectal cancer who are being followed on an outpatient
           basis at ECOG institutions.

      Secondary

        -  Determine if the number of symptom-related interventions are related to the providers'
           perception of symptom severity.

        -  Determine whether physical symptoms are more commonly prioritized and treated compared
           to psychological symptoms.

        -  Determine the percentage of patients who experience a significant reduction in
           moderate-to-severe symptoms and characterize the determinants of symptom relief.

        -  Determine the focus and scope of interventions chosen by oncologists to improve the
           symptom control of patients seen in outpatient clinics.

      OUTLINE: This is an open-label, multicenter study. Patients are stratified according to
      disease type, prevalence according to gender, race/ethnicity, age, and type of treatment.

      Patients complete the M.D. Anderson Symptom Assessment Inventory and other questionnaires,
      rating the symptoms most frequently found in this patient group and how much these symptoms
      interfere with mood and activity-related domains, on day 1 and again between days 28-35.

      At the same time points, a healthcare provider (treating physician, nurse, or physician
      assistant) completes the Revised Edmonton Staging System for Cancer Pain questionnaire,
      assessing the patient's cancer pain on the basis of mechanism of pain, incidental pain,
      psychological distress and addictive behavior, and cognitive function, for clinical prognosis
      on pain control.

      PROJECTED ACCRUAL: A total of 2,310 patients and their physicians will be accrued for this
      study.
    

Intervention name(s): assessment of therapy complications; cognitive assessment; psychosocial assessment and care
Intervention type(s): Procedure; Procedure; Procedure
Keywords: pain; psychosocial effects of cancer and its treatment; cognitive/functional effects; recurrent breast cancer; stage I breast cancer; stage II breast cancer; stage IIIA breast cancer; stage IIIB breast cancer; stage IIIC breast cancer; stage IV breast cancer; recurrent colon cancer; stage I colon cancer; stage II colon cancer; stage III colon cancer; stage IV colon cancer; recurrent rectal cancer; stage I rectal cancer; stage II rectal cancer; stage III rectal cancer; stage IV rectal cancer; extensive stage small cell lung cancer; limited stage small cell lung cancer; recurrent small cell lung cancer; recurrent non-small cell lung cancer; stage I non-small cell lung cancer; stage II non-small cell lung cancer; stage IIIA non-small cell lung cancer; stage IIIB non-small cell lung cancer; stage IV non-small cell lung cancer; recurrent prostate cancer; stage I prostate cancer; stage IIB prostate cancer; stage IIA prostate cancer; stage III prostate cancer; stage IV prostate cancer; male breast cancer; pulmonary carcinoid tumor