The Effects of Alginate Ag Dressing in the Pressure Injury Patients
Condition: Pressure Injury; Long-Term Care
MeSH terms: Wounds and Injuries; Crush Injuries
Study type: Interventional

Summary: 
      Wound infection and bleeding is a risk factor for pressure injury. Calcium alginate silver
      dressing (CASD) has been shown to be beneficial in a variety of wounds. However, evidence of
      its benefit in pressure injury(PI) patients in long-term care institutions, especially with
      respect to Taiwan population, is sparse. This study was to evaluate the effect of CASD and
      conventional wound dressings on the PI patients in long-term care institutions.
    

Detailed description: 
      Background: Wound infection and bleeding is a risk factor for pressure injury. Calcium
      alginate silver dressing (CASD) has been shown to be beneficial in a variety of wounds.
      However, evidence of its benefit in PI patients in long-term care institutions, especially
      with respect to Taiwan population, is sparse.

      Objective: To evaluate the effect of CASD and conventional wound dressings on the PI patients
      in long-term care institutions. The study hypothesis that when using the CASD will improving
      wound bed status more than conventional dressing change.

      Design: Prospective, randomized trial Setting: Multiple center long-term care institutions in
      Taiwan. Methods: In this clinical trial, 200 PI patients will randomly assigned to treatment
      with either calcium alginate silver dressing or conventional wound dressings for up to 14
      days or to the point of full reepithelialization of the wound. The length and depth of the
      studied wounds were recorded once a week. The instruments will using the PI measurement tool
      measured on day0, day7 and day14.The collected data were analyzed by descriptive and
      inferential statistical methods . The Mann-Whitney test was applied to compare primary
      endpoint between groups. Differences in secondary endpoint were also compared.

      Expected results: PI is an indicator of care quality in long-term care institutions. However,
      as the population ages, PI are prone to infection and bleeding problems, causing patients to
      have potential health problems such as sepsis and hemoglobin reduction. The results of this
      study will provide evidence-based care for wound dressing in long-term care institutions,
      thereby improving patient care.
    

Intervention name(s): Alginate silver silver ion dressing
Intervention type(s): Other
Intervention description(s): Alginate silver silver ion dressing is a soft, comfortable wound dressing with a high mannuronic acid content. Gels on contact with wound exudate or blood, creating a moist wound environment for optimal wound healing. Silver ions protect the dressing from a range of microorganisms.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Subjects who meet the inclusion criteria of this study will be randomly assigned by the research assistant to the experimental group or the control group by generating random numbers on the computer.
Masking: Double (Participant, Care Provider)
Primary purpose: Treatment
Keywords: pressure injury; patient; wound infection; nurses