Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy
Condition: Osteosarcoma; Ewing's Sarcoma; Rhabdomyosarcoma; Synovial Sarcoma; Malignant Peripheral Nerve Sheath Sarcoma; Malignant Fibrous Histiocytoma of the Bone; Chondrosarcoma of the Bone
MeSH terms: Neoplasms; Sarcoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma, Ewing; Chondrosarcoma; Sarcoma, Synovial; Histiocytoma; Histiocytoma, Benign Fibrous; Histiocytoma, Malignant Fibrous
Study type: Interventional

Summary: 
      This application proposes a prospective clinical trial to evaluate the impact of adding a
      focused physical therapy (PT) intervention to the preoperative regimen of individuals
      diagnosed with a malignancy of the lower extremity (LE). The primary aim will be to determine
      if individuals diagnosed with a malignancy of the LE can participate in a 10 week
      preoperative strengthening, stretching, and aerobic exercise regimen.
    

Detailed description: 
      The intervention group will receive PT 3 times per week for 60 minutes each session. The
      therapy sessions will include endurance, strengthening, and stretching exercises. Endurance
      exercises will consist of ambulating with assistive devices as needed, using the upper
      extremity (UE) ergometer, and/or playing the Wii. Strengthening exercises will involve both
      UE's and LE's. For UE's, bicep curls, triceps curls, shoulder flexion, and/or press-ups from
      the therapy mat or wheelchair will be included. For the LE's, bridging, long arc quads,
      hamstring curls, calf raises in standing, single LE squats, and/or dorsiflexion (DF) in
      supine will be performed on the uninvolved extremity. Resistance and exercise time will be
      increased depending upon participant's tolerance. Stretching will consist of ankle stretch
      into DF in supine or long sitting, hamstring stretch in supine with hip flexed to 90 degrees,
      and trunk extension in sitting.

      PRIMARY OBJECTIVE

      To determine if individuals diagnosed with a malignancy of the LE can participate in a 10
      week preoperative strengthening, stretching, and aerobic exercise regimen.
    

Intervention name(s): Endurance; Strengthening; Stretching; Home exercise program
Intervention type(s): Other; Other; Other; Other
Intervention description(s): Endurance exercise will consist of ambulating with assistive devices as needed, upper extremity (UE) ergometer, and/or playing the Wii.; Strengthening exercises will involve both UE's and LE's. For UE's, bicep curls, triceps curls, shoulder flexion, and/or press-ups from the therapy mat or wheelchair will be included. For the LE's, bridging, long arc quads, hamstring curls, calf raises in standing, single LE squats, and/or dorsiflexion (DF) in supine will be performed on the uninvolved extremity.; Stretching will consist of ankle stretch into DF in supine or long sitting, hamstring stretch in supine with hip flexed to 90 degrees, and trunk extension in sitting.; All participants will be given a tailored home exercise program (HEP) including endurance exercises, strengthening, and stretching exercises to be completed on days they do not have PT. If the participants return home, they will be asked to complete the HEP at least 3 days per week. The physical therapist will contact the participant weekly to modify the HEP if necessary and determine compliance.
Other intervention name(s): Physical therapy; Physical therapy; Physical therapy; Physical therapy
Intervention model: Single Group Assignment
Masking: None (Open Label)
Primary purpose: Supportive Care
Keywords: Lower extremity malignancy