Investigation of Factors Affecting Cardiorespiratory Fitness in Individuals With Systemic Hypertension
Condition: Systemic Hypertension; Muscle Weakness; Vascular Stiffness
MeSH terms: Muscle Weakness; Hypertension
Study type: Observational

Summary: 
      The investigators aim to investigate the factors affecting cardiorespiratory fitness in
      individuals with systemic hypertension.
    

Detailed description: 
      Systemic artery hypertension is a condition characterized by persistent high blood pressure
      (BP) in systemic arteries. Blood pressure is expressed as the rate of systolic BP (SBP)
      (pressure exerted by the blood on the arterial walls when the heart contracts) and diastolic
      BP (DBP) (pressure that occurs when the heart is relaxed).

      Hypertension is defined as SBP level ≥ 140 mmHg and DBP level ≥ 90 mmHg. Pre-hypertension,
      defined as the gray area, or increased normal blood pressure, ranges between SBP 130-139 mmHg
      and DBP 85-89 mmHg. Hypertension is among the most common preventable risk factors for
      cardiovascular diseases. Although hypertension, which is seen as a silent killer due to the
      absence of any symptoms in its early stages until a serious medical crisis such as heart
      attack, stroke or chronic kidney disease, is often asymptomatic, some patients may present
      with headache, dizziness, visual impairment or fainting spells. There is still too much
      uncertainty about the pathophysiology of hypertension. Fewer patients (between 2% to 5%) as
      the cause of increased blood pressure; there is an underlying kidney or adrenal disease.
      However, one reason is not clearly defined and in the rest condition "essential hypertension"
      is defined. A number of physiological mechanisms are involved in maintaining normal blood
      pressure, and irregularities of these mechanisms play a role in the development of essential
      hypertension. These physiological mechanisms; cardiac output and peripheral resistance,
      renin-angiotensin-aldosterone system, autonomic nervous system, vasoactive substances,
      excessive coagulation, insulin sensitivity, genetic factors, diastolic dysfunction and
      endothelial dysfunction.

      Evaluation of exercise capacity and prescribing individualized exercise programs in
      individuals with increased cardiovascular risk and risk factors is a protective and
      therapeutic health policy. Hypertensive individuals should be evaluated to evaluate motor and
      cardiovascular functions and prescribe exercise. Hypertension and the chronic diseases it may
      cause make it difficult for individuals to perform their daily life activities and may limit
      the participation of individuals in daily life. The exercise, being one of the most important
      components involved in the management of hypertension together hypertensive subjects of
      exercise capacity, activities of daily living (ADL), is considerably less than the studies
      that assessed in detail the balance parameters and the impact of hypertension as it is made
      in almost all geriatric population of the studies makes it difficult to demonstrate directly.
      The aim of our study is to evaluate individuals in terms of all these variables and to
      determine the factors affecting them, to examine the effect of antihypertensive drugs on
      daily life activity and exercise capacity, and to examine whether gender differences are
      observed.
    

Observational model: Other
Time perspective: Prospective
Sampling method: Probability Sample
Study population: 
        Stable hypertension patients between the ages of 18-65, who are in accordance with the
        criteria for inclusion in the clinical condition of Hacettepe University Faculty of
        Medicine, Department of Cardiology and Department of Nephrology from Hacettepe University
        Faculty of Medicine, Department of Internal Diseases, are included in the study. and who
        reffered to the Cardiopulmonary Rehabilitation Unit for Physiotherapy also who are willing
        to participate in the study will be include in the study.