Effect of Interferential Electrical Stimulation on Pain Perception and Disability Level on Interstitial Cystitis
Condition: Interstitial Cystitis
MeSH terms: Cystitis; Cystitis, Interstitial
Study type: Interventional

Summary: 
      A total of 40 volunteers women with a diagnosis of interstitial cystitis. Their ages ranged
      from 25 to 40 years old; their body mass index was > 30 kg/m2 and were randomly assigned to a
      group (A) received interferential current at the lower abdomen, and also received traditional
      medicine or group (B) received traditional medicine for 8 successive weeks. Both of the
      groups received the treatment program for 8 successive weeks. Assessment of pain perception
      and disability level for all patients in both groups (A&B) were done through Visual analogue
      scale, O'Leary-Sant Symptom Index or Interstitial Cystitis Index (ICSI) and blood cortisol
      concentration were done before and after the treatment program.
    

Detailed description: 
      Forty volunteers women diagnosed clinically by gynecologist as painful bladder syndrome were
      participated in this study. They were selected randomly from the gynecological outpatient
      clinic, at Al-Zahra Universal Hospital, Al Azhar University, their ages ranged from 25 to 40
      years and their body mass index was > 30 kg/m2. All participants complain from suprapubic
      pain related to bladder filling, accompanied by other symptoms such as increased daytime and
      night-time frequency. Exclusion criteria of the study were as follows: Participant who had
      acute viral disease, acute tuberculosis and mental disorders, benign or malignant tumors of
      the pelvic region, Participant who had active endometriosis or having artificial pacemaker or
      cardiac arrhythmia, Participant who had sensory disturbances.

      Participants were assigned randomly used sealed envelope into two groups (A&B) equally in
      number. Group (A): Consisted of twenty patients suffering from painful bladder syndrome. They
      received interferential current at the lower abdomen, and also received traditional medicine
      (they were administered anticholinergics (propiverine hydrochloride 20 mg/once per day in the
      morning) for 8 successive weeks. Group (B): Consisted of twenty patients suffering from
      painful bladder syndrome. They received traditional medicine (they were administered
      anticholinergics (propiverine hydrochloride 20 mg/once per day in the morning) for 8
      successive weeks
    

Intervention name(s): interferential current; Propiverine Hydrochloride
Intervention type(s): Device; Drug
Intervention description(s): Treatment was applied using four vacuum electrodes with wet sponge, two of them were put under the patient lumber region on a distance from lumber spinous process by five cm on each side and the other two were applied over the suprapubic region parallel to iliac crest.; propiverine hydrochloride 20 mg/once per day in the morning
Intervention MeSH terms: Propiverine
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: A total of 40 volunteers women with a diagnosis of interstitial cystitis. Their ages ranged from 25 to 40 years old; their body mass index was > 30 kg/m2 and were randomly assigned to a group (A) received interferential current at the lower abdomen, and also received traditional medicine or group (B) received traditional medicine for 8 successive weeks.
Masking: Double (Participant, Investigator)
Primary purpose: Treatment