The Effect of Robot-Assisted Gait Training in Stroke Patients
Condition: Stroke
MeSH terms: Stroke
Study type: Interventional

Summary: 
      Stroke has been defined by the World Health Organization as a condition with rapid onset and
      vascular origin, leading to a focal or global deterioration in brain functions lasting 1 day
      or longer. Stroke is an important health problem affecting a large part of the society with
      its high frequency and mortality. Post-stroke disability reduces the patient's quality of
      life and causes socioeconomic and social problems. Post-stroke hemiplegia often causes a
      decrease in the ambulatory ability of the patient. As a result, the patient's independence to
      move inside and outside the home is negatively affected. Gait is one of the most affected
      sensorimotor functions in stroke patients. Although the majority of patients strive to walk
      independently, they cannot reach a level of independent walking sufficient to perform
      activities of daily living (ADL). Current studies emphasize that the intensive early
      rehabilitation program is effective in treating patients with gait and movement disorders.
      Rehabilitation programs with a multidisciplinary approach are the most effective options that
      can be applied to increase a patient's functional status and post-stroke independence.
      Robotic-assisted walking devices are one of the current and effective methods used to regain
      ambulation.
    

Detailed description: 
      Robotic-assisted walking devices are used in the treatment of many neurological diseases such
      as spinal cord trauma, multiple sclerosis, post-stroke hemiplegia. In treatments applied with
      robotic walking devices, since accurate and equal weight transfer is provided in both lower
      extremities, sensorimotor learning of the patient is also supported. Thanks to the intense
      and repetitive simulation provided in every phase of the walk and the proprioceptive inputs
      taken, reorganization occurs in the cortical and sub-cortical regions. With the continuous
      facilitation of the walking cycle, neural transmission is regenerated or existing
      communication is strengthened between the motor areas of the brain and sensory pathways. The
      advantages of robotic systems can be listed as enabling longer and more intense treatments,
      ensuring that the patient feels better cognitively, adapting to exercise better, providing
      the opportunity to check the patient's condition objectively by monitoring and recording the
      patient's condition functionally. A recent systematic review showed that individuals with
      stroke who received robotic gait training combine with physiotherapy were more likely to
      achieve independent walking than those who received gait training without robotic gait
      training. Different studies on the effectiveness of robotic rehabilitation have reported that
      robot-assisted gait training should be applied together with a physiotherapy program.
      However, there is no clear information on the optimal dosage of Robot-Assisted Gait Training
      (RAGT) to achieve clinically meaningful functional recovery after a central nervous system
      injury. This study aims to investigate the effect of RAGT dosage on Functional Recovery and
      Quality of Life in patients with stroke.
    

Intervention name(s): Control; Robotic Group 1; Robotic Group 2
Intervention type(s): Other; Other; Other
Intervention description(s): Individuals in this group will be randomly recruited from hospitalized stroke volunteers. Since these individuals receive routine rehabilitation 5 days a week, they will be evaluated at the beginning and end of 18 sessions over a total period of 6 weeks. Conventional physiotherapy will include normal joint movements, muscle strengthening exercises, balance and mobility exercises, and exercises to improve daily life activity.; Individuals in this group will receive one session of robotic rehabilitation in addition to conventional therapy each week; Individuals in this group will receive two sessions of robotic rehabilitation in addition to conventional therapy each week
Other intervention name(s): Conventional therapy
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Three groups with one control group
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: Rehabilitation; Robotic; Stroke