Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins
Condition: Gastric Cancer
MeSH terms: Stomach Neoplasms
Study type: Interventional

Summary: 
      The investigators designed a prospective randomized, controlled clinical trial then recruited
      149 consecutive advanced gastric cancer patients. Further divided into a ERAS group (n=73)
      and a conventional pathway group (n=76). Surgical technique in both groups was same
      laparoscopic-assisted gastrectomy with D2 lymphadenectomy. Compared outcomes included
      clinical parameters and serum indicators.
    

Detailed description: 
      Enhanced recovery after surgery combined with laparoscopic-assisted gastrectomy was
      successfully carried out in this study. Recovery parameters such as the length of time to
      return to normal diet,mean hospital stay (d) were recorded.
    

Intervention name(s): ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; ERAS protocols; conventional pathway group; conventional pathway group; conventional pathway group; conventional pathway group; conventional pathway group; conventional pathway group
Intervention type(s): Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure; Procedure
Intervention description(s): Normal meal allowed until 6 h before surgery and Carbohydrate drink until 2 h before surgery; No bowel preparation; No nasogastric placement; if used, remove on the 1st postoperative day; Vasoactive drugs used if need be; Temperature management; Intra-abdominal drains not to be used; Intraperitoneal Ropivicaine infusion; On the 1st postoperative day Nasogastric catheter removed /Urinary catheter removed.
Oral non-opioid analgesia/Drinking 0.5L liquid. Active mobilisation; On the 2nd postoperative day：Drains removed Oral diet was initiated; 3-4th postoperative day： Stop oral non opioid analgesia; On the5-6th postoperative day Check discharge criteria; No solid foods at dinner before surgery and no liquids 12 h before surgery. Routine bowel preparation Nasogastric placement on the morning of surgery; Routine use of anesthesia medicine. Standard 5-trocar laparoscopy-assisted procedure. I.V. fluids not restricted (Ringer's lactate 20 ml/kg in the first hour, then at the rate of 10-12 ml/kg/h) Routine use of abdominal drainage tubes and placement of catheters.; 1st postoperative day: Keep Nasogastric catheter Removal of urinary catheter Opioid analgesic by intramuscular injection Parenteral nutrition until flatus. I.V. fluids not restricted Mobilization in bed; 2nd postoperative day Patient is advised to get out of bed until 24-48h after surgery; 3-4th postoperative day： Remove nasogastric tube after flatus Oral liquids started. Encouraged to walk in the ward.; 5-6th postoperative day：Oral diet was changed from liquids to semi-fluids and normal food.
Drains removed
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Treatment
Keywords: Enhanced recovery after surgery; laparoscopic gastrectomy; advanced gastric cancer; C-reactive,visceral proteins