Soccer Intervention in Prostate Cancer Survivors
Condition: Prostate Cancer
MeSH terms: Prostatic Neoplasms
Study type: Interventional

Summary: 
      This study seeks to directly test the implementation feasibility of a soccer-based and
      lifestyle education intervention to determine the effects on bone health, body composition,
      mental health, functional and cardiometabolic status among prostate cancer survivors.
    

Detailed description: 
      Prostate cancer (PCa) is the most common cancer in men in the U.S. and in other
      industrialized countries. The lifetime probability of PCa in males is one in nine, and it has
      a high economic burden, with costs expected to rise. Modern tailored treatment approaches,
      including androgen deprivation therapy (ADT), have resulted in longer life expectancy, but
      also longer treatment periods, which lead to significant adverse side effects. These often
      include decreased bone mineral density (BMD), increased risk of fractures, low functional
      capacity, loss of lean body mass (LBM), increased fat mass, insulin resistance, psychological
      distress and pain. Of particular concern is a sharp decline in bone health, with systemic
      bone loss caused by PCa-produced osteoclastogenic cytokines and drug interventions.
      Independent of disease stage, fractures in PCa patients are predictors of survival. In
      addition, concomitant physical inactivity and stress during and after treatment predispose
      PCa patients to elevated risk of deconditioning, BMD loss, cardiovascular and metabolic
      disease morbidity and mortality.

      Exercise-based lifestyle interventions aimed at counteracting treatment-induced adverse
      effects have been shown to be safe and effective in improving bone, functional and
      cardiometabolic health for patients with PCa. However, men, in general, are harder to engage
      in physical activity (PA) and lifestyle interventions. As an alternative to traditional
      exercise programs, recreational team sports provide a unique environment that may lead to
      increased physical activity participation and motivation to engage in other lifestyle
      changes. More than any other sport, recreational soccer (RS) has been shown to be a
      successful health intervention in patients with, or at risk of chronic diseases, including
      PCa.

      Leveraging the growing enthusiasm around soccer in Atlanta and the U.S. may lead to increased
      interest, participation, retention and engagement in lifestyle change programming among PCa
      survivors. Therefore, this study seeks to directly test the implementation feasibility of a
      soccer-based lifestyle change intervention to determine the effect on bone health, body
      composition, mental health, functional and cardiometabolic status among PCa survivors.

      Participants will be offered an intensive intervention including RS programming and lifestyle
      education. The group will receive RS, consisting of conditioning drills and games, adapted to
      the population during 60-minute sessions twice per week. The researchers will evaluate health
      outcomes at baseline and after 3 months of the intervention.
    

Intervention name(s): Soccer
Intervention type(s): Behavioral
Intervention description(s): Soccer drills and other fitness routines (two 1-hour sessions per week)
In person education in Life's Simple 7 to help improve life through Lifestyle changes: smoking status, physical activity, weight, diet, blood glucose, cholesterol, and blood pressure.
Other intervention name(s): Recreational Soccer (RS)
Intervention model: Single Group Assignment
Masking: None (Open Label)
Primary purpose: Prevention