Comparison of Wound Integrity for Clear Corneal Cataract Incisions
Condition: Cataract
MeSH terms: Cataract
Study type: Interventional

Summary: 
      This is a randomized controlled trial to evaluate the safety and efficacy of two different
      closing methods for clear corneal cataract incisions
    

Detailed description: 
      Compared with other incision types , clear corneal incision has the advantages of simple
      operation, small incision and good healing. It has been widely used in recent decades and has
      become the most commonly used incision type in phacoemulsification cataract surgery.However,
      there is no unified standard for the closed method of the clear corneal incision, and some
      studies have shown that the wound Integrity of clear corneal incision is not well.In the
      poorly closed incision, the risk of infection increased due to the leakage .Especially in
      2.2mm incision, the frequent entry and exit of the instrument reduces the corneal rebound
      ability at the incision so that the incision is hard to closed. Ensuring wound Integrity for
      clear corneal cataract incision is the key to the success of cataract surgery.

      Clinically closed methods include stromal hydration and suture.The effectiveness of stromal
      hydration as one of the most commonly used methods has been validated, but also adds
      additional negative effects. Additionally, the suture extends the operation time and improves
      the operation cost, and is also accompanied by some complications, which has been less used.
      Exploring a safe and effective closed method will benefit for most cataract patients.

      This study intends to evaluate the safety and efficacy of a closed method that incision is
      pressed by a cotton swab.The investigators planned to select 130 cataract patients who met
      the inclusion criteria. The investigators will press the clear corneal incision with a cotton
      swab in experimental group, while the control group used stromal hydration to close the
      corneal incision. Wound Integrity, wound leakage, corneal thickness at the incision,
      keratometric value at the incision, anterior chamber depth and incidence of incision-related
      descemet membrane detachment were compared between the two groups.
    

Intervention name(s): pressure by a cotton swab; stromal hydration with the balanced salt solution（BSS）
Intervention type(s): Procedure; Procedure
Intervention description(s): All patients undergo uneventful phacoemulsification by a 2.2 mm temporal transparent corneal incision using Centurion Vision System (Alcon Laboratories, Fort Worth, TX, USA). After the nucleus and cortex are removed, IOL is implanted in the capsular bag. Finally, the clear corneal incision is closed with pressure by a cotton swab.; All patients undergo uneventful phacoemulsification by a 2.2 mm temporal transparent corneal incision using Centurion Vision System (Alcon Laboratories, Fort Worth, TX, USA). After the nucleus and cortex are removed, IOL is implanted in the capsular bag. Finally, the clear corneal incision is closed with stromal hydration.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary purpose: Treatment