Screening Strategy for Asymptomatic Sexually Transmitted Infections (STI) in a Cohort of HIV Outpatients Men Who Have Sex With Men (DRIVER)
Condition: HIV
MeSH terms: Infections; Sexually Transmitted Diseases
Study type: Interventional

Summary: 
      Comparison of two screening strategies of asymptomatic sexually transmitted infections :
      routine screening versus screening as reported by the risks taken by the patient, in a cohort
      of HIV outpatients men who have sex with men. The aim of this study will be create and
      validate a simple tool for clinicians. A digital tool will be developed will allowed
      empowerment of HIV-positive men who have sex with men.
    

Detailed description: 
      Main objectives are :

      create and validate a risk score for STIs (DRIVER score) in a population of HIV-positive men
      who have sex with men (MSM).

      determine the prevalence of asymptomatic STIs in a population of HIV-positive MSM

      Secondary objectives are :

      compare 2 screening strategies regarding STIs in HIV-positive MSM (systematic screening vs
      screening according to self-declared risk factors) conduct a cost-efficiency analysis of both
      strategies evaluate patients' knowledge of STIs develop a DRIVER digital tool that will be
      made available to patients on websites, mobile apps…

      Position of the problem :

      Over the past 15 years, a resurgence of symptomatic STIs has been observed at both at the
      global and at the local (French) level. This has been true for gonorrhea since 2008, for
      syphilis since 2000 and for lymphogranuloma venereum since 2003. The epidemiology of
      asymptomatic STIs has not been studied as thoroughly but asymptomatic carriage of Neisseria
      gonorrhoeae and Chlamydia trachomatis as well as latent syphilis account for at least half of
      cases declared in the past few years. The population of HIV-positive MSM is the demographic
      category with the highest rates of STIs. In addition, risky sexual attitudes are on the rise
      in the MSM population in general (in 2010, the French RESIST Network reported that condom use
      during anal penetrations between males had dropped from 49% in 2008 to 37% in 2010).

      Screening practices are currently center- and healthcare-provider dependant. Study will allow
      a comparison of screening practices thanks to a score that will be built, validated and made
      available to clinicians and patients.

      Type of study : Prospective, non randomized, multicentric and cross-sectional Timeline :
      Study duration : 18 months Beginning of study : March 2015
    

Intervention name(s): creation of a STIs score risk; validation of a STIs score risk
Intervention type(s): Other; Other
Intervention description(s): 4 questionnaires 3 screening test ( syphilis, chlamydia, gonorrhea); DRIVER questionnaire (DRIVER STI score risk) 3 screening test ( syphilis, chlamydia, gonorrhea)
Other intervention name(s): First period; Second period
Allocation: Non-Randomized
Intervention model: Factorial Assignment
Masking: None (Open Label)
Primary purpose: Screening
Keywords: HIV-positive MSM (men who have sex with men); asymptomatic sexually transmitted infections; screening