How Has Glaucoma Affected Your Quality of Life?
Condition: Glaucoma; Quality of Life
MeSH terms: Glaucoma
Study type: Interventional

Summary: 
      Hypothesis 1: Self-reported health-related quality of life decreases as vision impairment
      worsens in subjects with glaucoma.

      Hypothesis 2: Changes in health-related quality of life are associated with changes in
      clinical measures of vision and performance-based measures of visual function.
    

Detailed description: 
      You are being asked to participate in this research study because you have glaucoma, which is
      the second leading cause of blindness in the world and accounts for 15% of blindness
      worldwide. Vision loss caused by glaucoma can significantly worsen your health-related
      quality of life. Despite the fact that glaucoma has such a big impact on a large number of
      people, research examining the long-term effects of glaucoma-related vision loss on one's
      quality of life is scarce.

      The purpose of this study is to look at the long-term effect of this condition on your
      quality of life so that we may gain valuable information about what factors influence the
      quality of life of people with glaucoma. To participate in this study, you will need to allow
      us to perform clinical tests on your eyes, to self-report your well-being and health-related
      quality of life, and to let us know how well you perform your daily life activities.
    

Intervention name(s): Clinical evaluation; Performance based measures; Subjective measures of vision-related quality of life
Intervention type(s): Other; Other; Other
Intervention description(s): Biomicroscopy (look at front of eye), ophthalmoscopy (look at back of eye), visual acuity, visual fields, intraocular pressure, spectral domain optical coherence tomography, Pelli-Robson and the Spaeth-Richman Contrast Sensitivity tests; Compressed Assessment of Ability Related to Vision (CAARV) items include: 1) computerized motion detection; 2) recognizing facial expressions; 3) reading street signs; and 4) finding objects in a room; National Eye Institute Visual Functioning Questionnaire 25 (NEI-VFQ-25) includes a series of questions pertaining to vision or feelings about a vision condition and the Modified Glaucoma Symptom Scale (MGSS) includes a series of questions pertaining to eye comfort.
Other intervention name(s): Ophthalmic examination; Compressed Assessment of Ability Related to Vision; Visual Functioning Questionnaire; Modified Glaucoma Symptom Scale
Intervention model: Single Group Assignment
Intervention model description: A prospective, longitudinal,observational cohort study to investigate how glaucoma affects patients' quality of life and visually-related function. Annual visits included (1) Clinical evaluation: a slit lamp examination, fundoscopy, intraocular pressure measurement, visual field examination, spectral domain optical coherence tomography, Pelli-Robson Contrast Sensitivity test and the Spaeth-Richman Contrast Sensitivity test; (2) a performance based measure: the Compressed Assessment of Ability Related to Vision; and (3) Subjective measures of vision-related quality of life (the National Eye Institute Visual Functioning Questionnaire 25 and the Modified Glaucoma Symptom Scale).
Masking: None (Open Label)
Primary purpose: Other
Keywords: Health related quality of life; Clinical measures of vision