Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinical Trial.
Condition: Peri-implant Mucositis
MeSH terms: Mucositis
Study type: Interventional

Summary: 
      The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with
      supportive home oral care for the treatment of peri-implant mucositis.

      Patients with bilateral implants with peri-implant mucositis will undergo professional dental
      hygiene with ultrasonic handpiece and manual scaler, followed by the application of glycine
      Airflow powders. Then, patients will be randomly divided into two groups: the Trial Group
      will undergo a split-mouth application of chlorhexidine gel 1% for quadrants 1 and 4 and of
      Biorepair Periogel 0.12% for quadrants 2 and 3, with one daily home application for the
      following 15 days after the visits and the use of Biorepair Parodontogel toothpaste; the
      control Group will not use any gels.

      The improvement of peri-implant mucositis will be evaluated between the two groups and
      differences between the two gels will be assessed, if present.
    

Detailed description: 
      The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with
      supportive home oral care for the treatment of peri-implant mucositis.

      Patients with bilateral implants with peri-implant mucositis will undergo professional dental
      hygiene with ultrasonic handpiece and manual scaler, followed by the application of glycine
      Airflow powders. Then, patients will be randomly divided into two groups:

        -  Trial Group: split-mouth application of chlorhexidine gel 1% for quadrants 1 and 4 and
           of Biorepair Periogel 0.12% for quadrants 2 and 3. Home oral care will be continued with
           1 application per day of the two gels for the following 15 days after the visits for the
           same quadrants, and the use of Biorepair Parodontogel Toothpaste.

        -  Control Group: no application neither of chlorhexidine gel nor of Biorepair Periogel.

      The improvement of peri-implant mucositis will be evaluated between the two groups and
      differences between the two gels will be assessed, if present, evaluating periodontal indices
      at the baseline, after three months and after six months.
    

Intervention name(s): Chlorhexidine and Biorepair gel and toothpaste application; Standard oral hygiene
Intervention type(s): Other; Other
Intervention description(s): Split-mouth application of chlorhexidine gel 1% (quadrants 1 and 4) and Biorepair Periogel (quadrants 2 and 3) after professional dental hygiene. Home oral care will be continued with chlorhexidine 0,12% gel and Biorepair Periogel in the same quadrants, for the following 15 days from the visits, together with the use of Biorepair Parodontogel toothpaste.; Use of standard toothpastes for home oral hygiene.
Intervention MeSH terms: Chlorhexidine
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary purpose: Treatment
Keywords: non-surgical periodontal therapy