Effect of Iodine Deficiency on Periodontitis
Condition: Periodontal Diseases; Periodontitis; Iodine Deficiency; Periodontitis, Adult
MeSH terms: Periodontitis; Periodontal Diseases; Chronic Periodontitis
Study type: Observational [Patient Registry]

Summary: 
      The goal of this observational study is to compare urine iodine levels of participants
      with/without periodontitis.

      The main question it aims to answer is there a relationship between iodine levels of urine
      and periodontitis.

      Participants will give urine samples without any intervention.
    

Detailed description: 
      Periodontitis is a chronic, inflammatory disease with a cyclical course with active and
      passive periods, which may result in the destruction of gingival fibers, resorption of
      alveolar bone, and subsequent tooth loss, by spreading the inflammatory event that started in
      the gingiva to the tissues supporting the tooth as a result of the effects of bacteria. The
      disease is closely associated with many systemic conditions. These conditions include
      diabetes, cardiovascular diseases, respiratory diseases, birth complications, pregnancy,
      puberty.

      Iodine deficiency is an important public health problem by affecting 10-15% of the population
      due to the diseases it causes. Iodine deficiency affects individuals of all ages. When the
      daily iodine requirement cannot be met, a group of mental, physical and developmental
      retardation symptoms called "Iodine deficiency disorders" (IEB) (Iodine deficiency
      disorders-IDD) occur. With the obligatory iodization of table salt, which started in 1998 in
      order to eliminate iodine deficiency in Turkey, this problem has been tried to be combated by
      switching to iodized salt consumption.

      The study material was used by 73 adult individuals who applied to Atatürk University Faculty
      of Dentistry, Department of Periodontology for different reasons {1. group (H): periodontally
      healthy individuals, group 2 (P): individuals with periodontitis}. Urine samples will be
      collected from the participants without any periodontal intervention. Iodine levels in the
      urine will be studied.

      There are studies in the literature to determine iodine deficiency and to determine the
      population periodontal disease status; however, there are no studies evaluating the possible
      relationship between iodine deficiency and periodontitis.

      The aim of this study; To evaluate the iodine levels detected in the urine samples of
      patients with periodontitis by comparing them with healthy controls, and to investigate the
      possible role of iodine deficiency in the pathogenesis of periodontitis or a simple marker of
      disease activity in the light of these findings.
    

Intervention name(s): healthy; periodontitis
Intervention type(s): Other; Other
Intervention description(s): no intervention; no intervention
Observational model: Case-Control
Time perspective: Cross-Sectional
Sampling method: Probability Sample
Study population: 
        individuals who referred to Atatürk University, Department of Periodontology
      
Biospecimen description: 
      urine of participants
    
Keywords: periodontitis; Iodine Deficiency