Effects of Blood Flow Restriction Training on Exercises in Healthy Individuals.
Condition: Health, Subjective
Study type: Interventional

Summary: 
      Partial restriction of blood flow to working muscles during exercise is proven to increase
      muscle mass and strength even with low-intensity of exercise. Blood Flow Restriction Training
      (BFRT) is also beneficial to improve the maximum rate of oxygen consumption (VO2max), bone
      health, and vascular health. Recent studies focus on its effects beyond the musculoskeletal
      system. Post-exercise hypotension is a known acute physiological response that happens after
      intense exercise. Early studies demonstrated BFRT might amplify the acute hypotensive effects
      with low intensity of exercise. However, it's not clear what type of exercise would help to
      lower blood pressure when it is combined with BFRT.
    

Detailed description: 
      Partial restriction of blood flow to working muscles during exercise is proven to increase
      muscle mass and strength even with low-intensity of exercise. Blood Flow Restriction Training
      (BFRT) is also beneficial to improve the maximum rate of oxygen consumption (VO2max), bone
      health, and vascular health. Recent studies focus on its effects beyond the musculoskeletal
      system. Post-exercise hypotension is a known acute physiological response that happens after
      intense exercise. Early studies demonstrated BFRT might amplify the acute hypotensive effects
      with low intensity of exercise. However, it's not clear what type of exercise would help to
      lower blood pressure when it is combined with BFRT. Considering BFRT, it's safe to implement
      among hypertensive individuals as per recent studies. It's still unclear what type of
      exercise would benefit maximum in reducing blood pressure while using it along BFR. The study
      aims to determine whether BFRT can influence BP, MAP, HR, and muscle girth differently while
      doing resisted exercises and aerobic exercise. Understanding the effects of BFRT on these
      parameters can provide valuable insights for optimizing exercise protocols and improving
      overall health outcomes. In general, this study can also add to the increasing amount of
      studies about the possible advantages and drawbacks of BFRT, and provide guidance on how to
      design exercise programs for people with borderline hypertension or in those with early phase
      of hypertension.
    

Intervention name(s): Aerobic exercises; Resisted exercises
Intervention type(s): Procedure; Procedure
Intervention description(s): This group received a single session of low-intensity cycling for 20 minutes. A period of reperfusion (3 to 5 minutes) were provided in both groups after 10 minutes of exercise training by deflating the BFR cuffs. The cuffs were inflated after 5 minutes of reperfusion, and the exercises were completed in both groups.; This group received four sets of 15 repetitions of knee extension, hamstring curls, and standing calf raises (20-40% 1RM) with 30 sec to 1 minute rest period between sets. A period of reperfusion (3 to 5 minutes) were provided in both groups after 10 minutes of exercise training by deflating the BFR cuffs. The cuffs were inflated after 5 minutes of reperfusion, and the exercises were completed in both groups.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary purpose: Treatment
Keywords: Blood flow Restriction Training; Blood Pressure; Heart Rate; Mean Arterial Pressure; Muscle Girth