Thenar Tissue Oxygen Concentration (StO2): A Non-invasive Surrogate for Central Venous Oxygen Saturation (ScvO2)
Condition: Oxygen Concentration Levels
Study type: Observational

Summary: 
      Oxygen concentration for patients undergoing cardiac catheterization and during admission to
      an intensive care unit is important outcome measure for clinical care. Currently, the tool
      used to monitor the oxygen concentration is a central venous access positioned in the
      superior vena cava or in the pulmonary artery to monitor the central venous oxygen saturation
      (ScvO2). However, it is invasive and not always possible due to a lack of a central line
      access. In this research study, the investigator would like use a noninvasive means for the
      ScvO2 by using the thenar tissue oxygen concentration (StO2). The primary aim for the study
      is to determine if the thenar StO2 correlates with ScvO2 and can serve as a noninvasive
      surrogate for ScvO2.
    

Detailed description: 
      Participants will be undergoing a cardiac catheterization at Shands Children's Hospital or
      will be admitted to the intensive care unit, and as part of the clinical care either a
      central venous access positioned in the superior vena cava or in the pulmonary artery. As a
      part of the routine clinical care blood gases are frequently taken for continuous evaluation
      of therapy to monitor the central venous oxygen saturation (ScvO2). A measurement of thenar
      tissue oxygen concentration will be timed with a central venous blood gas draw to monitor the
      tissue oxygen concentration (StO2).

      The StO2 measurement will be taken by using the InSpectraTM StO2 monitor manufactured by
      Hutchinson Technology Inc. after applying the noninvasive clip on probe to the thenar
      eminence of the right hand to measure the StO2 level. After a stable reading is obtained for
      60 seconds it will be recorded.

      The two different measurements of oxygen concentration will be compared to determine if a
      correlation exists.
    

Intervention name(s): StO2 measurement; Blood Gases
Intervention type(s): Device; Other
Intervention description(s): All participants will have a measurement of the tissue oxygen concentration (StO2) level after applying the noninvasive probe to the thenar eminence. This measurement is done at the same time as a blood gas from the central venous catheter is obtained. The StO2 measurement is documented once for the subject in the study.; All participants will have a measurement of the tissue oxygen concentration (StO2) level after applying the noninvasive probe to the thenar eminence. This measurement is done at the same time as a blood gas from the central venous catheter is obtained. The StO2 measurement is documented once for the subject in the study.
Other intervention name(s): InSpectraTM StO2 monitor; central venous oxygen saturation (ScvO2)
Observational model: Case-Only
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        Participants will be undergoing a cardiac catheterization atan area Children's Hospital or
        will be admitted to the intensive care unit, and as part of the clinical care.