The Effects of Nutritional on Disease Activity and Functional Status in RA
Condition: Rheumatoid Arthritis
MeSH terms: Arthritis; Arthritis, Rheumatoid
Study type: Observational [Patient Registry]

Summary: 
      Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disease.

      RA is a chronic inflammatory disease in which many patients cannot achieve remission despite
      current pharmacological treatments. Chronic inflammation in RA causes an increase in
      metabolic index and nutritional requirements. In recent studies, it is mentioned that diet
      regimens and foods consumed in nutrition affect inflammation.

      The aim of this study is to evaluate the nutritional status and habits of patients with RA
      and to examine their effects on disease activity level, quality of life and functional
      status.

      A questionnaire form will be applied to collect data on demographic information, disease
      activity, nutritional status and habits, physical activity status and physical functional
      status of the patients included in the study.
    

Detailed description: 
      Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disease affecting
      0.5-1.0% of the population. RA is a chronic inflammatory disease in which many patients
      cannot achieve remission despite current pharmacological treatments. Chronic inflammation in
      RA causes an increase in metabolic index and nutritional requirements. In recent studies, it
      is mentioned that diet regimens and foods consumed in nutrition affect inflammation.

      The aim of this study is to evaluate the nutritional status and habits of patients with RA
      and to examine their effects on disease activity level, quality of life and functional
      status.

      This study will be conducted with 100 patients diagnosed with RA in Balıkesir University,
      Health Practice and Research Hospital, Department of Physical Medicine and Rehabilitation
      outpatient clinic.

      Patients between the ages of 18-75, diagnosed with RA according to the ACR 2010 diagnostic
      criteria, with a disease duration of 2 or more, using less than 10 mg of prednisolone per
      day, will be included in the study. Patients with a duration of ≤2 years after the diagnosis
      of RA, a change in the use of DMARDs and/or biological agents in their medical treatment for
      the last 8 weeks, using prednisolone more than 10 mg daily, malignancy, pregnant, lactating,
      and those who cannot understand the information in the questionnaire was not included in the
      study.

      A questionnaire form will be applied to collect data on demographic information, disease
      activity, nutritional status and habits, physical activity and physical functional status of
      the patients included in the study.

      As a result of this study, it is aimed to help patients with rheumatoid arthritis reach
      remission with diet programs and recommendations in addition to existing drug treatments.
    

Intervention name(s): questionnaire form
Intervention type(s): Other
Intervention description(s): A questionnaire will be applied to all participants. A questionnaire form will be applied to collect data on demographic information, pain, disease activity, nutritional habits, physical activity status and physical functional status of the patients included in the study.
Observational model: Case-Crossover
Time perspective: Cross-Sectional
Sampling method: Probability Sample
Study population: 
        Patients aged 18-75 years, with a disease duration of at least 2 years or more, diagnosed
        with RA according to ACR 2010 diagnostic criteria,
      
Keywords: Rheumatoid Arthritis, nutrition, inflammation