Examination of the Effect of Skin Antisepsis With Pre-heated Povidone Iodine on Surgical Site Infections: A Quasi-Experimental Study
Condition: Surgical Site Infections
MeSH terms: Infections; Communicable Diseases; Surgical Wound Infection
Study type: Interventional

Summary: 
      Surgical Site Infections (SSI) develop as a complication of surgical care 30-90 days after
      surgery without implants and within 1 year after implanted operations. Despite advances in
      asepsis practices, sterilization methods, surgical technique and antibiotic prophylaxis, SSI
      is the most important cause of hospital stay, morbidity and even mortality. SSI, which
      constitutes approximately 20% of healthcare associated infections (HAI) all over the world,
      is also the HAI with the highest cost. Although it has been reported that 60% of the SSI can
      be prevented by using evidence-based guidelines, 2-5% of the operated patients develop SSI,
      the hospital stay of patients with SSI is 7-11 days longer, the risk of death increases 2-11
      times, It was reported that the cause of death was direct SSI. In the United States of
      America (USA), SSI constitutes 31% of HAI, it is seen in 2-5% of inpatients, approximately
      160,000-300,000 SSIs occur each year, the most common and costly HAI.Abdominal surgery; It
      includes the treatment of diseases of organs such as stomach, gall bladder, pancreas, spleen,
      liver, small intestine and large intestine. It has been reported that the incidence of SSIs
      after abdominal surgery is 15-25% higher than other types of surgery. In a study conducted by
      Alcan et al. (2020), 69.8% of nurses stated that they used Povidone Iodine as skin
      antisepsis. Wistrand et al. (2015) compared preoperative 36 ° C and room temperature 20 ° C
      Chlorhexidine Gluconate solutions, but reported that there was no difference in bacterial
      colonization and SSI rates. In their study in Turkey, Gezer et al. (2020) reported that the
      prevalence of SSI was significantly lower in the Povidone Iodine group heated to 37 ° C
      before surgery compared to the Povidone Iodine group applied at 25 ° C room temperature.
    

Detailed description: 
      This study was planned in accordance with a single blind randomized controlled full
      experimental study design to determine the effect of skin antisepsis with Povidone Iodine,
      which was heated at 37°C and at a room temperature of 20°C in the preoperative period, in
      reducing surgical site infections in patients who underwent abdominal surgery. Patients who
      will undergo abdominal surgery at Dr. Burhan Nalbantoğlu State Hospital will comprise the
      sample of volunteer patients who meet the inclusion criteria and agree to participate in the
      study. The data of the study was planned to be collected using the Patient Information Form,
      Surgical Site Infection Follow-up Form and Post Discharge Patient Follow-up Form.
    

Intervention name(s): Follow-up
Intervention type(s): Diagnostic Test
Intervention description(s): The primary outcome of this study was SSI within 30 days of surgery, as defined by the Centers for Disease Control and Prevention. Secondary outcomes were identification of the causative organism, and investigation of clinical factors such as body mass index (BMI), operation time, days of hospitalization, etc. that may be associated with SSI.
All patients were followed up for SSI until discharge from hospital and at the outpatient visits. SSI surveillance data forms were used for the collection of primary and secondary outcome data.
SSI rates and distribution of identified micro-organisms for each group will measured
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Care Provider)
Primary purpose: Screening
Keywords: Povidone Iodine; Skin antisepsis; Abdominal Surgery