African American Depression Intervention Trial (AADI)
Condition: Major Depressive Disorder
MeSH terms: Depression; Depressive Disorder; Depressive Disorder, Major
Study type: Interventional
Phase: Phase 3

Summary: 
      Primary Aim 1: Examine effectiveness of the Oh Happy Day Class (OHDC) compared to the Coping
      With Depression (CWD)in increasing retention, adherence, engagement, satisfaction, and
      treatment-seeking. The investigators hypothesize the OHDC compared to the CWD will result in
      greater increases in: 1a. retention, 1b. adherence, 1c. engagement, and 1d. satisfaction at
      the middle and end of the intervention, and 2.e. greater increase in treatment-seeking 3-,
      6-, 9-, and 12- months post-intervention. Outcome measures: logs: attendance, homework
      completion, class-participation level; Client Satisfaction Inventory; and Cornell Service
      Index. Primary Aim 2: Examine effectiveness of the OHDC in reducing symptoms of depression at
      the middle and immediate end of the intervention, and 3-, 6-, 9-, and 12- months
      post-intervention. The investigators hypothesize the OHDC will result in greater reduction in
      depressive symptoms compared to the CWD at 3-months post-intervention. Outcome measures:
      Center for Epidemiologic Studies Depression Scale and Quick Inventory of Depression Symptoms.
      Secondary Aim 3: Examine the effectiveness of the OHDC in improving self-reports of mental
      and physical health status and reducing self-reports of perceived disability. The
      investigators hypothesize the OHDC compared to the CWD will result in greater self-report of:
      3a. improved mental and physical health status, and 3b. reduced self-report of disability at
      the immediate end of the intervention and 3-,6-, 9-, 12- months post-intervention. Outcome
      measures: SF-12 Health Survey, and World Health Organization Disability Assessment Schedule.

      Public Health Impact: Based on CAI research, the OHDC has the potential to be four times more
      effective than the CWD. If our hypotheses are proven, the OHDC will be the first
      evidence-based culturally adapted depression intervention designed specifically for African
      American men and women between the ages of 30-60.
    


Intervention name(s): Coping with Depression Course (CWD) and Oh Happy Day Class (OHDC)
Intervention type(s): Behavioral
Intervention description(s): The OHDC is a culturally adapted, cognitive behavioral group counseling intervention. The OHDC is theoretically grounded in social learning theory and an Afrocentric paradigm (Nguzo Saba). It uses a social support group and psychoeducation format so participants learn skills to help them in coping and reducing symptoms of depression. The OHDC is offered over 13 weeks with 2-hour sessions in a clinical setting.
The CWD, an evidence-based cognitive behavioral depression intervention. The CWD is offered over 8 weeks with 2-hour sessions in a clinical.
Arms: lifestyle counseling (OHDC), lifestyle counseling (CWD)
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Depression