Effectiveness and Implementation of a Mindfulness Intervention for Depressive Symptoms Among Adults in a FQHC
Condition: Depressive Symptoms; Stress, Psychological; Stress, Physiological
MeSH terms: Depression; Stress, Psychological
Study type: Interventional

Summary: 
      The objective of this project is to examine the clinical effectiveness of a mindfulness
      intervention on reducing depressive symptoms among socio-economically disadvantaged,
      racial/ethnic minority adults and explore factors related to implementation in a Federally
      Qualified Health Center (FQHC). This research will be used to develop a generalizable model
      for delivery of streamlined mental health interventions in community based settings that will
      be broadly disseminated and scalable to other populations. Black and Hispanic adults are more
      likely than those who are White to receive depression treatment in primary care, where
      antidepressants are the most commonly offered treatment. However, Black and Hispanic adults
      are less likely than Whites to find antidepressants acceptable. A mindfulness depression
      intervention provided within primary care may be more accessible and acceptable for
      low-income, racial/ethnic minority individuals, a severely underserved population. The
      investigators will conduct a randomized controlled trial to test the clinical effectiveness
      of a mindfulness intervention (M-Body) on reducing depressive symptoms, compared to usual
      care, among low-income racial/ethnic minority adults in a FQHC. The M-Body intervention is
      based on Mindfulness Based Stress Reduction and has been tailored for the FQHC setting and
      patient population. Adults (N=254) with depressive symptoms will be recruited from a FQHC in
      the Chicago, IL area that serves majority racial/ethnic minority individuals (90%) living at
      or below the poverty line (74%). Half of the patients will be randomized to the M-Body
      intervention arm where they will receive 8-weeks of mindfulness training led by FQHC staff
      and the other half will be randomized to usual care. Information on factors relevant to
      implementation of the intervention in the FQHC will be obtained by convening a series of
      workgroups and individual interviews with FQHC staff, executive leadership and community
      stakeholders. Specific Aims: 1) Determine the effectiveness of M-Body on reducing depressive
      symptoms compared to enhanced usual care for racial/ethnic minority adults in a FQHC; 2)
      Explore potential mediators (stress related biomarkers, mindfulness) and moderators (age,
      personal, social, environmental stressors) of the intervention's effect; 3) Conduct a broad
      assessment of organizational and individual agency factors related to preparation and
      implementation of the M-Body intervention in a FQHC using a mixed methods approach.
    


Intervention name(s): mindfulness
Intervention type(s): Behavioral
Intervention description(s): 8-week mindfulness based group intervention
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary purpose: Treatment