Investigation in Integrated Perspective of Radiculomyelopathy Patients
Condition: Cervical Myelopathy; Cervical Radiculopathy
MeSH terms: Radiculopathy; Spinal Cord Diseases
Study type: Interventional

Summary: 
      Cervical radiculopathy and myelopathy are common degenerative disorders, which can create a
      large amount of social and medical burden. The aims of this study are(1) to investigate the
      functional outcomes progression before and after surgery, (2) to evaluate the biomechanical
      change and compensatory patterns of patients with or without decompression surgery, and (3)
      to design innovation intervention for the patients with cervical myelopathy and
      radiculopathy.
    

Detailed description: 
      Neck pain, which is common in population recently, is causing the huge burden in the global
      medical service system. Cervical myelopathy, that is induced by disc degeneration, is turning
      to be an alarming public health issue. The clinical manifestations of cervical myelopathy
      include neck/shoulder pain, numbness/weakness of four limbs, sensorimotor impairment, and
      sociopsychological dysfunction. However, most of the previous studies tend to justify
      patients, prognosis in a single dimension. The investigators realized that no standard
      protocol for management in patients with the variety of manifestation and severity of signs
      and symptoms.This study is purposed to integrate and analyze the finding in surgery
      selection, clinical manifestation, psychological consultation, compensatory patterns in the
      neuromusculoskeletal system, postural control, home exercise and biomechanical features.
      Then, the investigators will develop a complementary model in assessment and prediction of
      prognosis, and also an applicable standard guideline in the clinical setting. To achieve the
      expected target, the principal investigator will play the role as the main coordinator in the
      team. The 3-year plan is listed as below:

        1. In the first year, the patients will be recruited for projects from different
           co-investigators. The recruited participants will be allocated to different study group
           after assessment to ensure the most suitable intervention are offered to the
           participants.

        2. In the second year, the participants' recruitment will be continuing. The effectiveness
           previous treatment will be assessed. The study procedure will be adjusted based on pilot
           results.

      2. In the third year, the study finding of all co-investigators and results of the
      biomechanical analysis will be integrated to establish the model of prognosis prediction and
      clinical management guideline. This study will provide a complete clinical management
      guideline in cervical myelopathy, which is expected to be globally leading reference in the
      management of cervical myelopathy.
    

Intervention name(s): specific rehabilitation exercise
Intervention type(s): Other
Intervention description(s): specific rehabilitation exercise for patients with cervical myelopathy
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Other
Keywords: decompression surgery; functional outcome; biomechanic; rehabilitation