Effect of Different Types of Aerobic Training on Peak VO2 and Ejection Fraction for Diastolic Heart Failure Patients; a Comparative Randomized Control Trial
Condition: Effect of Different Types of Aerobic Training on Diastolic Heart Failure Patients
MeSH terms: Heart Failure; Heart Failure, Diastolic
Study type: Interventional

Summary: 
      Background: Heart failure is described by a lack of confirmed efficient therapies and
      exercise intolerance. Physical activity is related to a lower risk of adverse cardiovascular
      consequences, involving heart failure. The purpose of the study: determine the effect of
      different types of aerobic training on peak VO2 and ejection fraction in diastolic heart
      failure patients. Subject and methods: Forty eligible male patients with diastolic heart
      failure, aged between 50 - 60 years old, participated in this study. They were selected from
      an outpatient clinic of general Zagazig hospital and were assigned into 2 equal groups in
      numbers. The first group (A) received aerobic exercise for the upper limb in form of arm
      ergometer exercises, while the second group (B) received aerobic exercise for the lower limb
      in form of cycling. Training duration for both groups was 3 sessions/week for 12 weeks. Peak
      VO2, and ejection fraction of both groups were measured and compared pre and post-treatment.
      Results: There was no significant difference in the ejection fraction between groups
      post-treatment. There was a significant increase in the peak VO2 of group B compared with
      that of group A post-treatment. Conclusion: there is no effect of different types of aerobic
      training on ejection fraction and peak VO2 for diastolic heart failure patients, but lower
      limb exercise is more effective than upper limb exercise in improvement of peak VO2 for
      diastolic heart failure patients.
    

Detailed description: 
      Ejection fraction and peak VO2 of both groups were measured pre exercise program and after 12
      weeks at the end of the study exercise program.

        -  Vivid S5 cardiovascular ultrasound system (BT308), made in china, was used to measure
           ejection fraction.

        -  Oxycon pro (ER900, Germany) cardiopulmonary exercise test unit was used to measure Peak
           Vo2

      Treatment procedure:

      Group A received aerobic exercise for upper limb in the form of arm ergometer 3 session/week
      for 12 weeks. Patient started with warming up for 5 minutes in form of stretching. Patients
      used arm ergometer without resistance for upper limb aerobic exercise for 20 minutes and
      instructed to take rest if they feel tired or fatigue. The intensity was according to rate of
      perceive exertion, after 20 minutes, patients were asked to cool down for 5 minutes in the
      form of stretching at the end of an exercise session.

      Group B received aerobic exercise for lower limb in the form of cycling 3session/week for 12
      weeks. Patient started with warming up for 5 minutes. Patients used bicycle for lower limb
      aerobic exercise for 20 minutes and instructed to take rest if they feel tired or fatigue.
      The intensity was according to rate of perceive exertion. After 20 minutes, patients were
      asked to cool down for 5 minutes in the form of stretching at the end of an exercise session.
    

Intervention name(s): aerobic exercise for upper limb; aerobic exercise for lower limb
Intervention type(s): Other; Other
Intervention description(s): aerobic exercise for upper limb in the form of arm ergometer 3 session/week for 12 weeks. Patient started with warming up for 5 minutes in form of stretching. Patients used arm ergometer without resistance for upper limb aerobic exercise for 20 minutes and instructed to take rest if they feel tired or fatigue. The intensity was according to rate of perceive exertion, after 20 minutes, patients were asked to cool down for 5 minutes in the form of stretching at the end of an exercise session.; received aerobic exercise for lower limb in the form of cycling 3session/week for 12 weeks. Patient started with warming up for 5 minutes. Patients used bicycle for lower limb aerobic exercise for 20 minutes and instructed to take rest if they feel tired or fatigue. The intensity was according to rate of perceive exertion. After 20 minutes, patients were asked to cool down for 5 minutes in the form of stretching at the end of an exercise session.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Supportive Care
Keywords: Diastolic heart failure; ejection fraction; aerobic exercise; peak VO2