Sedation and Nursing Management in EEG Recording in Children
Condition: Electroencephalography; Melatonin; Chloral Hydrate; Hydroxyzine; Sleep Deprivation
MeSH terms: Sleep Deprivation
Study type: Interventional

Summary: 
      Electroencephalogram (EEG) has an important place in establishing the correct diagnosis,
      providing appropriate intervention, and predicting the prognosis in the long term in
      children. When the literature is examined, it is seen that different sedative drugs
      (benzodiazepines, barbiturates, phenothiazine, chloral hydrate, hydroxyzine, melatonin, etc.)
      and their combinations are used to provide sedation during EEG recordings, but there is no
      ideal sedative drug. Nurses working in the field of pediatric neurology in EEG recordings; It
      has important roles in preparing the child and parent for the procedure, applying sedation
      before the procedure, performing the EEG recording properly, monitoring vital signs during
      the procedure, monitoring the effects of the sedative substance after the procedure, and
      sending the patient home safely. Pediatric nurses fulfill these roles by adopting a
      multidisciplinary team approach. In this context, the aim of our research is; The aim of this
      study is to evaluate the effects of chloral hydrate, hydroxyzine and melatonin, which are
      used as sedative agents before EEG recording in children, on sleep success, time to fall
      asleep, side effects and EEG background.
    

Detailed description: 
      The aim of this study is to evaluate the effects of chloral hydrate, hydroxyzine and
      melatonin, which are used as sedative agents before EEG recording in children, on sleep
      success, time to fall asleep, side effects and EEG background.It is a randomized controlled
      experimental study.The universe of the study consisted of all children who had EEG recordings
      in the Pediatric Neurology Outpatient Clinic of a tertiary hospital. Its sample is; It
      comprised 180 children aged 1-7 years who met the inclusion criteria, evaluated for epilepsy,
      suspected epilepsy, febrile convulsions, and other neurological diseases.G power program was
      used to determine the sample size of the study. For each group (chloral hydrate, hydroxyzine,
      melatonin and natural sleep) 45 individuals were included in the study by taking 95% power
      and 0.05 margin of error while making the calculation. Randomization was carried out in the
      study in order to provide an equal number of samples for each group (chloral hydrate,
      hydroxyzine, melatonin and natural sleep) and to avoid bias. "Block randomization method" was
      used in order to provide equal samples for all four groups in randomization.Data Collection
      tools of the research; Child's Information Form, Ramsay Sedation Score, Steward Recovery
      Score. Statistical analyzes of the study were performed with the SPSS 20.0 (IBM Incorp,
      Chicago, IL, USA) program. Descriptive measures were frequency (percentage ratio) for
      categorical variables, mean±SD and median for numerical variables; It was presented as Q1-Q3.
      Conformity of continuous numerical measurements to normal distribution was tested by
      Kolmogorov-Smirnov method, but it was found that it did not fit normal distribution (p
      <0.05). Multivariate logistic regression model was established to determine the properties
      that are effective on sedative substances. A p value of <0.05 was considered statistically
      significant in the entire study. In order to conduct the study, ethical approval from the
      Antalya Training and Research Hospital Clinical Research Ethics Committee, approval from the
      Turkish Medicines and Medical Devices Agency, institutional permission from the hospital
      where the study will be conducted, and written consent from the participants were obtained.
    

Intervention name(s): Sedation and Nursing Management in EEG Recording in Children; Chloral Hydrate; Hydroxyzine; Melatonin
Intervention type(s): Other; Drug; Drug; Drug
Intervention description(s): Evaluation of the effect of sedative agents applied during EEG recording in children; Chloral Hydrate; Hydroxyzine; Melatonin
Intervention MeSH terms: Melatonin; Chloral Hydrate; Hydroxyzine
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Supportive Care