Intradialytic High-Intensity Interval Training in Hemodialysis Patients
Condition: End Stage Renal Disease; Exercise, Compulsive
MeSH terms: Kidney Failure, Chronic; Compulsive Exercise
Study type: Interventional

Summary: 
      Chronic Kidney Disease (CKD) is defined as a chronic, progressive degeneration state in the
      regulation of the fluid-electrolyte balance of the kidney and metabolic-endocrine functions
      as a result of the glomerular filtration rate (GFR) falling below 60 ml/min/1.73 m²,
      regardless of the etiology of the kidney disease. End Stage Renal Failure (ESRD) is the last
      stage of CRF and is a life-threatening condition. Although the majority of ESRD patients
      survive on dialysis, their quality of life and functional capacity decrease due to uremic
      cardiomyopathy, cardiovascular diseases, anemia, diabetes mellitus, bone diseases,
      deconditioning, fatigue, weakness, inactivity and accompanying psychological problems.

      Rehabilitation program including exercise in CKD patients; The program, which is performed
      under observation on non-dialysis days, can be applied in three ways: the (intradialytic)
      rehabilitation program performed during hemodialysis in the dialysis unit, and the home
      exercise program. Intradialytic exercise (IDE) is defined as exercise training performed
      during the hemodialysis session to increase the patient's strength and endurance and thus
      target various physiological and psychosocial parameters. Three types of exercises are
      generally recommended in the exercise program for dialysis patients. These are aerobic
      exercise, strengthening exercise, and combined aerobic and resistance exercise program.
      Aerobic exercise (both on dialysis and on non-dialysis days) is the most common type of
      exercise used in hemodialysis patients. It is stated that physical exercise improves the
      exercise capacity, muscle strength, functional capacity and quality of life of patients
      receiving dialysis treatment, provides blood pressure control, reduces the risk of diabetes
      development and cardiovascular disease, alleviates depression and anxiety symptoms, increases
      survival and dialysis efficiency.

      When the literature is examined, no study has been found that examines how the application of
      high-intensity intermittent exercise training, which has very important advantages, in the
      intradialytic process has an effect. Therefore, the aim of our study is to compare the
      effects of intradialytic high-intensity intermittent exercise training and moderate-intensity
      exercise training on dialysis effectiveness, functional capacity and quality of life in
      hemodialysis patients.
    


Intervention name(s): High Intensity Interval Exercise Training; Moderate Intensity Exercise Training
Intervention type(s): Other; Other
Intervention description(s): High Intensity Interval Training Group; Moderate Intensity Training Group
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Treatment
Keywords: intradialytic exercise; high-intensity interval training; chronic kidney disease; dialysis adequacy; functional capacity