The Effect of Exercise in Water on Functional Fitness in People With Parkinson's Disease
Condition: Parkinson; Parkinson Disease; Neurologic Disorder
MeSH terms: Parkinson Disease; Nervous System Diseases
Study type: Interventional

Summary: 
      The goal of this clinical trial study is to learn about the effect of aquatic exercise in
      parkinson's patients. The main questions it aims to answer are:

        -  What is the effect of exercise in water on balance in parkinson's patients?

        -  What is the effect of exercise in water on muscle strength in parkinson's patients?

        -  What is the effect of exercise in water on flexibility in parkinson's patients?
           Parkinson's patients in this study will do some functional tests. One group of them will
           do exercises in water 3 times weekly for 8 weeks.
    

Detailed description: 
      Parkinson's disease (PD) is a progressive, neurodegenerative movement disorder characterised
      by the motor symptoms bradykinesia, tremor, rigidity, and postural instability. These are
      commonly associated with non-motor disturbances, neurobehavioural symptoms and reduced
      quality of life.

      Exercise is currently recommended as an additional strategy to manage PD-induced disability
      and is a key component of rehabilitation programs for people with PD.

      Aquatic exercise is another form of non-conventional exercise that has been growing in
      popularity in the context of neurorehabilitation.16 The aquatic setting offers specific
      mechanical advantages due to the hydrostatic and hydrodynamic principles of buoyancy,
      viscosity and drag.

      Due to its ability to enhance functional mobility whilst also being enjoyable,aquatic
      exercise has become a very popular form of physical training in the management of
      neurodegenerative disorders.

      Recent studies suggest that high-intensity interval training (HIIT) is promising for
      promoting neuroplasticity in human PD, with short training time and reduced burden.
      Biomarkers for neuroplasticity such as brain-derived neurotrophic factor (BDNF) and
      neurodegeneration (including neurofilament light chain ((NfL) and α-synuclein) may play a
      role, but their response to HIIT is not well-investigated.

      The aims of this study are to investigate the effects of HIIT exercises in water on balance,
      muscle strength, flexibility and gait speed in PD patients.
    

Intervention name(s): Exercise in water
Intervention type(s): Other
Intervention description(s): Participants will do some exercises in water for 30-60 minutes. Exercises will be performed at a moderate exercise intensity (12-14 on the Borg Rate of Perceived (RPE) Scale).
All protocols are tailor-made based on each individual's needs and physical abilities.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Participants will be randomly allocate to intervention group or control group and will be examined in the same way
Masking: Single (Outcomes Assessor)
Primary purpose: Supportive Care
Keywords: Parkinson Disease; Aqua Therapy; Balance; Neurological Disorders