Effect of Different Exercise Modalities Training in Patients With Obstructive Sleep Apnea.
Condition: Obstructive Sleep Apnea
MeSH terms: Apnea; Sleep Apnea Syndromes; Sleep Apnea, Obstructive
Study type: Interventional

Summary: 
      The objective of this study was to compare different exercise modalities (moderate continuous
      intensity training, high intensity interval training, and inspiratory muscle training) on
      Apnea-Hypopnea index and oxidative stress in patients with Obstructive sleep apnea.
    

Detailed description: 
      Forty patients with OSA aged 20 and 50 years old, dividing into 4 groups (MICT, HIIT, IMT,
      and CON) by stratified (with sex, age, and OSA severity) and single random sampling. The MICT
      group received 50 minutes of running at 65-70% of maximum heart rate 3 days/week for 12
      weeks. The HIIT groups received 28 minutes of running (High intensity at 85-90% of maximum
      heart rate 2 minutes interval with low intensity 50-55% of maximum heart rate 2 minutes) 3
      days/week for 12 weeks. The IMT group received Powerbreathe ® device, performing 240 breath
      (8 sets) per day at 50% of Maximal inspiratory pressure (MIP), 5 days/week for 12 week. The
      CON group did not have any intervention but usual care. Data collection was split 2 days (1st
      day for polysomnography evaluation, and 2nd day for questionnaire, blood collection, body
      composition, exhaled nitric oxide, pulmonary function, respiratory muscle strength and
      aerobic capacity). All variables were measured before and after exercise program.
    

Intervention name(s): Moderate continuous training (MICT); High intensity interval training (HIIT); Inspiratory muscle training (IMT); Control
Intervention type(s): Other; Other; Other; Other
Intervention description(s): The participants received a moderate continuous training (MICT) program of walking or running a treadmill 3 days/week, 12 weeks. This training comprises 5 minutes of warm up at 50-55% of maximal heart rate, following by 50 minutes of exercise at 65-70% of maximal heart rate, and 5 minutes of cool down at 50-55% of maximal heart rate. The intensity of exercise increases to 70-75% of maximal heart rate at week 7-12.; The participants received a 7x2 high intensity interval training (HIIT) program of walking or running a treadmill 3 days/week, 12 weeks. This training comprises training comprises 5 minutes of warm up at 50-55% of maximal heart rate, following by 28 minutes of exercise (2 minutes of high intensity at 85-90% of maximal heart rate interval with 2 minutes of low intensity at 50-55% of maximal heart rate 7 times), and 5 minutes of cool down at 50-55% of maximal heart rate. The intensity of exercise at high intensity increases to 90-95% of maximal heart rate at week 7-12.; The participants received Powerbreathe ® ClassicLight in this training program. The IMT group demonstrated the training 8 cycles of 30 breath, 5 days/week with progressive load 50% of maximal inspiratory pressure (MIP) at week 1-3, 60% of MIP at week 4-6, 70% of MIP at week 7-9, and 80% of MIP at week 10-12. Every first day of the week participants had to undergoing load adjustment at laboratory; The CON group did not have any intervention but usual care.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: HIIT; Pulmonary function; Sleep; Exercise; Polysomnography