bioihbjkbjnl/mcl2 huggingface dataset:
Yoga on Posttraumatic Growth and Quality of Life
Condition: Posttraumatic Growth; Quality of Life
Study type: Interventional

Summary: 
      The objective of this study is to examine the effect of yoga on posttraumatic growth and
      quality of life. The birth action, which includes positive and negative experiences, can be
      an important opportunity to achieve posttraumatic growth and improve the quality of life.

      This is a experimental model with pretest-posttest control group study. Two hundred and
      fifty-two women who met the criteria for inclusion in the study made up the research
      population. Three instruments were used to obtain the research data: Personal Information
      Form, Posttraumatic Growth Inventory (PTGI) and SF-36 Quality of Life Questionnaire (SF-36).
    

Detailed description: 
      Failure in modern medicine approaches or side effects of treatments and drugs, as well as the
      woman's anxiety to hurt herself and her baby direct her and her relatives to try
      complementary therapies. Women should prefer natural ways in coping with these postpartum
      problems rather than seeking medical advice.

      When yoga and meditation, which are included in the group of mind-body-based complementary
      therapies, are performed in the postpartum period, they will help to relieve tensions and
      distresses that accumulate during birth, strengthen the pelvic floor, heal perineum, bring
      reproductive organs back to their prepregnancy condition healthily, provide the mother and
      the infant a sleep pattern, and have an easier transition to sleep.
    

Intervention name(s): Yoga
Intervention type(s): Behavioral
Intervention description(s): Yoga Practice and Program: Yoga practice consisted of 10 weeks. Yoga practice involved following stages; 5-minute breathing exercises in standing or sitting position, 40-minute postpartum period specific asanas and last 15- minute deep relaxation in lying position were made by the researcher.
Allocation: Randomized
Intervention model: Crossover Assignment
Intervention model description: Randomized Controlled trial with a prospective pretest-posttest experimental model
Masking: Single (Participant)
Primary purpose: Supportive Care
Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic Impairment
Condition: Hepatic Insufficiency
MeSH terms: Hepatic Insufficiency; Liver Failure
Study type: Interventional
Phase: Phase 1

Summary: 
      The purpose of this study is to assess the effects of hepatic impairment on the single dose
      pharmacokinetics of BMS-790052.
    


Intervention name(s): BMS-790052
Intervention type(s): Drug
Intervention description(s): Capsules, Oral, 30 mg, single dose, one day
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
BPA Levels Relationship With IVF/ICSI Outcomes in Patients With Male Factor
Condition: Infertility, Male; IVF
MeSH terms: Infertility; Infertility, Male
Study type: Interventional

Summary: 
      Association between blood and semen BPA levels and ICSI outcomes in patients with male factor
    


Intervention name(s): BPA levels
Intervention type(s): Other
Intervention description(s): BPA (Bisfenol A) in blood and ejaculate samples
Intervention model: Single Group Assignment
Masking: None (Open Label)
Primary purpose: Supportive Care
Research on Suicidal Ideation of University Students in Harbin City and Cognitive Behavior Therapy
Condition: Suicide
MeSH terms: Suicide; Suicidal Ideation
Study type: Interventional

Summary: 
      The purposes of this research are:

        -  to understand the status of suicidal ideation, suicidal behavior, and depression in
           Harbin University students; and

        -  to analyse the infect factors of suicidal ideation and suicidal behavior.

      With cognitive behavior interventions on students with suicidal ideation, suicidal behavior,
      and middle or high degree of depression, the researchers can provide a scientific and
      effective intervention to the students.

      Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial.

      Brown GK, Ten Have T, Henriques GR, Xie SX, Hollander JE, Beck AT. Department of Psychiatry,
      University of Pennsylvania, Philadelphia 19104, USA. gregbrow@mail.med.upenn.edu JAMA. 2005
      Aug 3;294(5):563-70.
    

Detailed description: 
      By using suicidal ideation scale, to assess the status of suicidal ideation and suicidal
      attempt in 6000 university students in Harbin city. About 300 students with suicidal ideation
      and depression disorder randomized into two groups (control and intervention groups) accept
      the cognitive behavior intervention. We will assess the depression after intervention.
    

Intervention name(s): cognitive behavior therapy
Intervention type(s): Behavioral
Intervention description(s): cognitive behavior therapy once a week
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Prevention
Keywords: Suicidal ideation; cognitive behavior therapy
A Prospective Study to Evaluate the Safety of a New Trivalent Intranasal Influenza Vaccine
Condition: Influenza
MeSH terms: Influenza, Human
Study type: Interventional
Phase: Phase 4

Summary: 
      This prospective annual release study was designed to assess the safety of a trivalent
      influenza virus vaccine using a new strain recommended for the 2008-2009 influenza season not
      previously contained in the trivalent intranasal FluMist vaccine. Three hundred healthy
      adults received a single dose of vaccine or placebo and were followed for 180 days.
    

Detailed description: 
      This was a prospective, randomized, double-blind, placebo-controlled release study. Eligible
      subjects were randomly assigned in a 4:1 fashion to receive a single dose of trivalent
      vaccine or placebo by intranasal spray. Randomization was stratified by site. Each subject
      received 1 dose of study vaccine on Study Day 0. The duration of study participation for each
      subject was the time from study vaccination through 180 days after study vaccination.
    

Intervention name(s): Trivalent influenza virus vaccine; Placebo
Intervention type(s): Biological; Biological
Intervention description(s): Trivalent vaccine was supplied in intranasal sprayers containing a total volume of 0.5 ml of sucrose-phosphate buffer, egg allantoic fluid, and approximately 10:7 FFU (fluorescent focus units) of each of three cold-adapted, attenuated, 6:2 reassortant influenza strains A/South Dakota/6/07 (H1N1), A/Uruguay/716/07 (H3N2), and B/Florida/4/2006.; Placebo was supplied in intranasal sprayers containing 0.5 ml of sucrose-phosphate buffer.
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary purpose: Prevention
Keywords: Influenza; FluMist; vaccine; prevention; trivalent
Study to Assess the Effect of Gabapentin Enacarbil on Simulated Driving in Healthy Subjects
Condition: Restless Legs Syndrome (RLS)
MeSH terms: Psychomotor Agitation; Restless Legs Syndrome
Study type: Interventional
Phase: Phase 1

Summary: 
      This is a double-blind, placebo-and active-controlled 3-period crossover study designed to
      assess the effect of GEn 600 mg on simulated driving performance in healthy volunteers.
    

Detailed description: 
      proportional systemic gabapentin exposure over a wide dose range. This is a double-blind,
      placebo-and active-controlled 3-period crossover study designed to assess the effect of GEn
      600 mg on simulated driving performance. Subjects will receive each of 3 treatments in a
      randomized order: GEn 600 mg, placebo and placebo/diphenhydramine 50 mg. Each treatment
      period will consist of 6 days, with subjects being dosed at approximately 5 pm on each dosing
      day. The placebo /diphenhydramine treatment will consist of placebo on Days 1-4 and 6 and 50
      mg diphenhydramine on Day 5. Placebo will be administered on Day 6 in all treatment periods
      to ensure washout of drug prior to the start of the next treatment period. Simulated driving
      performance will be assessed at baseline (prior to randomization) and on Day 5 in the evening
      (7-9 pm) and on Day 6 between7-9 am and between 11am-1pm for each treatment period.
    

Intervention name(s): gabapentin enacarbil; diphenhydramine; placebo
Intervention type(s): Drug; Drug; Drug
Intervention description(s): 600 mg investigational compound; 50 mg active comparator; placebo
Other intervention name(s): XP13512; GSK1838262
Intervention MeSH terms: Diphenhydramine; Promethazine; Gabapentin
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary purpose: Treatment
Keywords: gabapentin; restless leg syndrome
Candesartan Effect in Second Stage Arterial Hypertension
Condition: Stage II Hypertension
MeSH terms: Hypertension
Study type: Interventional
Phase: Phase 4

Summary: 
      To compare the changes in mean sitting DBP from baseline after 4 weeks of therapy with either
      candesartan cilexetil/HCT combination therapy or candesartan cilexetil monotherapy regimen
    


Intervention name(s): Candesartan Cilexetil; Hydrochlorothiazide; Candesartan Cilexetil
Intervention type(s): Drug; Drug; Drug
Intervention description(s): Candesartan Cilexetil 16 mg oral; Hydrochlorothiazide 12.5 mg; Candesartan Cilexetil 32 mg oral
Other intervention name(s): Atacand; HCTZ; Diazide; Atacand
Intervention MeSH terms: Hydrochlorothiazide; Candesartan; Candesartan cilexetil
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Candesartan Cilexetil; hydrochlorothiazide; severe hypertension
Investigation of the Effectiveness of Dynamic Neuromuscular Stabilization Exercises After Lumbar Disc Herniation Surgery
Condition: Low Back Pain; Kinesiophobia
MeSH terms: Intervertebral Disc Displacement; Low Back Pain; Kinesiophobia
Study type: Interventional

Summary: 
      The aim of the study is to investigate the effects of dynamic neuromuscular stabilization
      exercises on pain, functionality and fear in individuals who have undergone lumbar disc
      herniation surgery.
    

Detailed description: 
      The research was planned as a randomized controlled trial, which is a quantitative study.
      Participants will be divided into 2 groups as control and exercise groups by simple
      randomization method. The individuals in the control group of the study will not be given any
      exercise program after surgery. A home exercise program created with Dynamic Neuromuscular
      Stabilization exercises after surgery will be applied to the individuals in the intervention
      group. Data collection will be carried out through an online survey. The scales and forms to
      be used before and after the treatment are respectively: 1. Oswestry Low Back Pain Disability
      Questionnaire 2. International Physical Activity Questionnaire (Short Form) 3. Questionnaire
      for Fear of Daily Living Activities The questionnaires will be uploaded to the Google Forms
      database and the participants will be accessed via e-mail or mobile phone applications. .
      They will be asked to fill out the questionnaires before starting the post-surgical exercise
      program and the exercise program will be explained practically before discharge. The
      exercises will be planned 3 times a week and for 8 weeks.
    

Intervention name(s): exercise; control
Intervention type(s): Other; Other
Intervention description(s): The dynamic neuromuscular stabilization group will receive developmental postures based on developmental kinesiology. It will involve a supine 3month Position, side-lying Position, Quadruped, oblique sitting, bear position, squat Position. Each position will be performed for 30-60 s for five reps, active exercise 5-10 reps under supervision for two days/week, and unsupervised for 3 days/week for 8 weeks; No intervention will be made.
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: The dynamic neuromuscular stabilization exercises
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Keywords: pain; Neuromuscular Stabilization exercises; Kinesiophobia; surgical
Iron Supplementation of Marginally Low Birth Weight Infants
Condition: Anemia; Iron-Deficiency; Child Behavior Disorders; Cognitive Manifestations
MeSH terms: Neurobehavioral Manifestations; Anemia, Iron-Deficiency; Iron Deficiencies; Birth Weight; Mental Disorders; Child Behavior Disorders
Study type: Interventional
Phase: Phase 4

Summary: 
      Iron is essential for brain development and there is a well established association between
      iron deficiency in infants and poor neurological development. In Sweden, about 5% of newborns
      have low birth weight (< 2500 g). Due to small iron stores at birth and rapid postnatal
      growth, they have increased risk of iron deficiency and it is therefore important to prevent
      iron deficiency in this population. However, excessive iron supplementation can have adverse
      effects in infants such as growth impairment. In a randomized, controlled trial, we are
      investigating the effects of 0, 1 or 2 mg/kg/d of iron on brain myelination, cognitive
      development and growth in low birth weight infants.
    


Intervention name(s): Iron
Intervention type(s): Drug
Intervention description(s): Ferrous succinate mixture
Other intervention name(s): Ferromyn S, AstraZeneca, Södertälje, Sweden
Intervention MeSH terms: Ferrous succinate
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary purpose: Prevention
Keywords: Iron supplements; Infant; Low birth weight; Prevention of iron deficiency and its physiological consequences; Safety
Patient-Specific Versus Conventional Instrumentation in TKA
Condition: Osteoarthritis, Knee
MeSH terms: Osteoarthritis, Knee
Study type: Interventional

Summary: 
      The aim of this prospective multicenter randomized clinical trial (RCT) is to compare the
      clinical and radiologic results of primary total knee arthroplasty (TKA) using
      patient-specific versus conventional instrumentation.
    


Intervention name(s): PSI; Conventional instrumentation
Intervention type(s): Device; Device
Other intervention name(s): Patient specific instrumentation
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment
Tolerability and Pharmacokinetics of Telmisartan in Combination With Lacidipine in Healthy Male Subjects
Condition: Healthy
Study type: Interventional
Phase: Phase 1

Summary: 
      The trial objectives were to investigate the tolerability and pharmacokinetics of 80 mg
      telmisartan and 2, 4 or 6 mg lacidipine administered concurrently.
    


Intervention name(s): Telmisartan; Lacidipine; Placebo
Intervention type(s): Drug; Drug; Drug
Intervention MeSH terms: Telmisartan; Lacidipine
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Double
Primary purpose: Treatment
A Multi-centre Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)
Condition: Colorectal Cancer
MeSH terms: Colorectal Neoplasms
Study type: Interventional
Phase: Phase 4

Summary: 
      To compare the polyp and adenoma detection rate of MOVIPREP versus an oral Sodium
      Picosulfate/Magnesium Citrate solution.
    


Intervention name(s): MOVIPREP; CitraFleet
Intervention type(s): Drug; Drug
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Investigator)
Primary purpose: Screening
Safety and Pharmacokinetics of Intravenous and Oral Posaconazole in Immunocompromised Children (MK-5592-097)
Condition: Neutropenia
MeSH terms: Neutropenia
Study type: Interventional
Phase: Phase 1

Summary: 
      This study aims to evaluate the pharmacokinetics of posaconazole (POS) administered
      intravenously (IV) or orally to immunocompromised pediatric participants.
    


Intervention name(s): Posaconazole IV solution; Posaconazole powder for oral suspension
Intervention type(s): Drug; Drug
Intervention description(s): Posaconazole by IV solution twice on Day 1, then once daily on Days 2-10.; Posaconazole once daily by PFS for a minimum of 10 days
Other intervention name(s): Noxafil; Noxafil
Intervention MeSH terms: Posaconazole
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Prevention
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
Condition: Allergic Rhinitis; Asthma in Children; Dental Caries; Periodontal Diseases
MeSH terms: Rhinitis; Dental Caries; Periodontal Diseases; Asthma; Rhinitis, Allergic
Study type: Observational

Summary: 
      The aim of the study was to evaluate if there were differences in oral findings between
      patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
    

Detailed description: 
      The aim of the study was to evaluate if there were differences in oral findings between
      patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
      At the oral evaluation, the following indexes were calculated: PSR, Periodontal Screening and
      Recording; PI, Plaque Control Record and DMFT, Decayed Missing Filled Teeth Index. Absence or
      presence of mouth breathing was also recorded. Linear regressions were calculated to compare
      the oral findings with gravity of allergic rhinitis, to asthma compensation and to asthma
      treatment.
    

Intervention name(s): Oral examination
Intervention type(s): Diagnostic Test
Intervention description(s): Patients underwent oral examination with the recording of DMFT, PSR, PI and presence/absence of mouth breathing.
Observational model: Cohort
Time perspective: Prospective
Sampling method: Probability Sample
Study population: 
        Patients addressing to the Pediatric clinic of Fondazione IRCCS Policlinico San Matteo,
        Pavia, Italy for medical care.
AutoSet for Her Clinical Trial Protocol
Condition: Obstructive Sleep Apnea
MeSH terms: Sleep Apnea Syndromes; Sleep Apnea, Obstructive
Study type: Interventional

Summary: 
      The purpose of this study is to assess the efficacy and user preference of the Newport
      AutoSet for Her in female obstructive sleep apnea (OSA) patients.

      Efficacy will be evaluated by comparing the apnea and hypopnea index (AHI) and oxygen
      desaturation index (ODI) of the Newport AutoSet for Her algorithm to a standard algorithm.

      User preference will be evaluated by subjective feedback relating to comfort, ease of falling
      asleep, sleep disturbance and feeling of being refreshed.
    


Intervention name(s): Standard AutoSet algorithm; Modified AutoSet algorithm
Intervention type(s): Device; Device
Intervention description(s): An AutoSet device with a standard algorithm developed for sleep breathing parameters that are specific to a particular gender.; An AutoSet device with an algorithm developed for sleep breathing parameters specific to females.
Other intervention name(s): AutoSet for Her
Allocation: Randomized
Intervention model: Crossover Assignment
Masking: Single (Participant)
Primary purpose: Treatment
Keywords: Obstructive sleep apnea; Efficacy; Subjective feedback; Preference
no Antibiotics for Elective Cesarean With Low Risk of Infection
Condition: Antibiotics , Elective Cesarean, China
MeSH terms: Infections
Study type: Observational [Patient Registry]

Summary: 
      The purpose of this study is to discuss whether the parturients who underwent elective
      cesarean of such kind do not need prophylactic use of antibiotics and evaluate the risks and
      economic benefits involved.
    


Observational model: Case-Control
Time perspective: Prospective
Sampling method: Probability Sample
Study population: 
        antibiotics group:202 none antibiotics group:212
      
Keywords: antibiotics, cesarean
Menopausal Health Training for Husbands on Women's Quality of Life and Marital Satisfaction
Condition: Menopause
Study type: Interventional

Summary: 
      The investigators conducted a clinical trial to evaluation the effect of a menopausal health
      training for Husbands of 45-60 years women on the women's quality of life and marital
      satisfaction during transitional period to menopause.
    

Detailed description: 
      The investigators applied a menopausal health training program for Husbands of 45-60 years
      women. The content of menopausal health training program was about the nature of menopause,
      signs and symptoms, complications, treatment option and health behavior during transitional
      period. Training program lasted 3 sessions. The investigators assessed quality of life and
      marital satisfaction using Hildich marital satisfaction questionnaire and Menopause Quality
      of Life questionnaire(MENQOL), respectively, three month after intervention.
    

Intervention name(s): Training program about menopausal health isues
Intervention type(s): Other
Intervention description(s): A three sessions raining program about health issues during menopause for spouses of 45-60 years old
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Keywords: Menopause; Quality of Life; Marital Satisfaction; training