Quality of Life in Children Treated for Cancer
Condition: Leukemia; Lymphoma; Unspecified Childhood Solid Tumor, Protocol Specific
MeSH terms: Lymphoma; Leukemia
Study type: Observational

Summary: 
      RATIONALE: Questionnaires that measure quality of life may improve the ability to plan
      treatment for children with cancer.

      PURPOSE: This randomized clinical trial is studying the quality of life in children treated
      for cancer.
    

Detailed description: 
      OBJECTIVES: I. Assess the validity and reliability of a quality of life questionnaire
      (MM-QOL) that is being developed for patients with previously or currently treated childhood
      cancers.

      OUTLINE: This is a randomized, multicenter study. Patients are stratified according to age
      (8-12 vs 13-20) and treatment (current vs previous). Patients are randomized to one of two
      arms of the study. Arm I (Reliability): Patients will complete the same questionnaire two
      weeks apart. (age 13-20 stratum closed as of 7/14/00) Arm II (Validity): Patients will
      complete a study questionnaire plus a Child Health Questionnaire. Patients between ages 8-12
      are interviewed and patients between ages 13-20 complete a written questionnaire.

      PROJECTED ACCRUAL: A total of 716 patients (416 for arm I (208 for 8-12 age group and 208 for
      13-20 age group) and 300 for arm II (150 for 8-12 age group and 150 for 13-20 age group))
      will be accrued for this study.
    

Intervention name(s): Quality of Life Forms
Intervention type(s): Other
Intervention description(s): Completion of the instrument [Minneapolis-Manchester Quality of Life (MM-QOL)] that measures HRQOL in the survivors of childhood cancer in a standardized, valid way and to assess the feasibility of incorporating this endpoint in a variety of clinical trials.
Time perspective: Cross-Sectional
Sampling method: Probability Sample
Study population: 
        Previous treatment for cancer or currently undergoing treatment for cancer.
      
Keywords: recurrent childhood acute lymphoblastic leukemia; childhood Burkitt lymphoma; stage I childhood lymphoblastic lymphoma; stage II childhood lymphoblastic lymphoma; stage III childhood lymphoblastic lymphoma; stage IV childhood lymphoblastic lymphoma; recurrent childhood lymphoblastic lymphoma; recurrent childhood acute myeloid leukemia; childhood diffuse large cell lymphoma; childhood immunoblastic large cell lymphoma; unspecified childhood solid tumor, protocol specific; childhood acute myeloid leukemia in remission; stage II childhood Hodgkin lymphoma; stage I childhood Hodgkin lymphoma; stage III childhood Hodgkin lymphoma; stage IV childhood Hodgkin lymphoma; recurrent/refractory childhood Hodgkin lymphoma; stage I childhood small noncleaved cell lymphoma; stage I childhood large cell lymphoma; stage II childhood small noncleaved cell lymphoma; stage II childhood large cell lymphoma; stage III childhood small noncleaved cell lymphoma; stage III childhood large cell lymphoma; stage IV childhood small noncleaved cell lymphoma; stage IV childhood large cell lymphoma; recurrent childhood small noncleaved cell lymphoma; recurrent childhood large cell lymphoma