In Vivo Comparative Study of Calcium Hydroxide and Triple Antibiotic Paste in Intracanal Medicament in Emergency Pain Reduction
Condition: Pain
MeSH terms: Emergencies
Study type: Interventional

Summary: 
      Interappointment pain is a universal concern for clinician and patients alike which remain a
      significant challenge for dentalprofessional.The purpose of this study was to evaluate the
      effects of calcium hydroxide, and triple antibiotic paste as intra-canal medicaments in
      emergency pain reduction in patients undergoing endodontic treatment .
    

Detailed description: 
      Before commencing treatment, the complete procedure was explained to the patients and consent
      was obtained. Local anesthesia was administered, and the tooth was isolated under rubber dam.
      Access cavity preparation was done, and canals were explored using endodontic explorer
      (DG-16,). Working length was determined with No. 15 K-files using apex locater and was
      confirmed with radiovisiography . Cleaning and shaping were along with copious irrigation
      using 3% NaOCl and 0.9% saline . Canals will be dried and one of the following two
      medicaments will be inserted into the canals in random sequences

      Group 1 :Calcium Hydroxide:

      CH was placed as an intracanal medicament. Atotal of 100 mg of CH powder was dispensed and
      mixed with one drop of pro-pylene glycol on a clean and dry glass slab to prepare a thick
      paste-like consistency. This paste was carried into the canal , and access opening was
      restored temporarily with temporary cement

      Group 2: Triple antibiotic paste:

      It was prepared by removing the coating and crushing of antibiotic
      ciprofloxacin500mg,metronidazole 400mg,, and clindamycin tablets separately using a mortar
      and pestle. The crushed powder was passed through a fine sieve to remove heavy filler
      particles and obtain a fine powder. The ciprofloxacin, metronidazole, and clindamycin powders
      thus obtained were weighed separately and mixed in a 1:3 proportions respectively,to obtain
      triple antiobiotic mixture.A total 100 mg of this Ta mixture was dispensed and mixed with one
      drop of propylene glycol to get a thick paste-like consistency. This paste was placed gently
      compacted into the canal , and access opening was restored with temporary cement Before
      dismissal ,no antiobiotics will be prescribed and the patients who had been taking
      antibiotics will be recorded.Patient will be requested to stop antibiotics.They will be
      requested to stop analgesic.The preoperative pain experienced on the previous night will be
      recorded using visual analogue scale.Patient will be then instructed to record the degree of
      pain experienced after 2nd day ,7th day and 15 day postoperatively
    

Intervention name(s): Calcium Hydroxide; Triple Antibiotic paste
Intervention type(s): Drug; Drug
Intervention description(s): After completion of canal and shaping ,canal was dried and CH was placed as an intracanal medicament. A total of 100 mg of CH powder was dispensed and mixed with one drop of pro-pylene glycol on a clean and dry glass slab to prepare a thick paste-like consistency. This paste was carried into the canal and access opening was restored temporarily with temporary cement; After completion of cleaning and shaping ,canal was dried and tripe antibiotic was placed as intracanal medicament.It was prepared by removing the coating and crushing of antibiotic ciprofloxacin500mg,metronidazole 400mg,, and clindamycin tablets separately using a mortar and pestle. It was prepared by removing the coating and crushing of antibiotic ciprofloxacin500mg,metronidazole 400mg,, and clindamycin tablets separately using a mortar and pestle. This paste was placed gently compacted into the canal and access opening was restored with temporary cement
Intervention MeSH terms: Anti-Bacterial Agents; Calcium
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Investigator)
Primary purpose: Treatment