An Investigation of the Effect of Types of Catheters on Bloodstream Infection in Patients With Major Burns: Prediction With Procalcitonin and Prognosis
Condition: Burns
MeSH terms: Infections; Sepsis; Burns
Study type: Interventional

Summary: 
      Bloodstream infections and catheter-related infections frequently occur in burn patients. It
      is important to correctly assess and manage these infections. The present study aimed to
      investigate the effects of catheter types used in major burn patients on bloodstream
      infections as well as to predict sepsis status and manage its prognosis using a procalcitonin
      biomarker.
    

Detailed description: 
      Aim:

      Bloodstream infections and catheter-related infections frequently occur in burn patients. It
      is important to correctly assess and manage these infections. The present study aimed to
      investigate the effects of catheter types used in major burn patients on bloodstream
      infections as well as to predict sepsis status and manage its prognosis using a procalcitonin
      biomarker.

      Materials and Methods:

      A total of 34 patients admitted to the intensive care unit of the Burn Center, December 25th
      State Hospital, Ministry of Health, between 2019 and 2022, were included in the study
      conducted at the Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences,
      Hasan Kalyoncu University.

      Study inclusion criteria

        -  Conscious and cooperative (based on the Glasgow coma score; eyes open spontaneously (E):
           4, obeys commands (M): 6, oriented verbal (V) response: 5; and E4M6V5);

        -  Enterally fed, aged over 18 years;

        -  No antibiotic treatment from hospitalization to discharge;

        -  Meets the major burn class standards defined by the American Burn Association; and

        -  Stable hemodynamic values and vital signs with no need for inotropic medication.

      Study exclusion criteria

        -  Organ dysfunctions or multiple organ failures

        -  Antibiotics treatment Nutrient types and diets were the same in all groups. All patients
           received similar standard medical care and treatment from the time of emergency
           admission and acute care of the burn injury until the time of discharge. In addition,
           types and numbers of clinical interventions, such as surgical debridement and grafting,
           were similar in all groups. All patients who were included in this study were assessed
           for four weeks from the first day of hospitalization and taken to the treatment program.

      Patients included in the study were divided into two groups based on whether they used PVCs
      or CVCs. Patients' procalcitonin, thrombocyte, and leukocyte levels were assessed every other
      day for 4 weeks, beginning on the first day they were admitted to the burn center. The above
      examinations at the Laboratories of the December 25th State Hospital, Ministry of Health of
      the Republic of Turkey, were retrieved retrospectively from the hospital database.

      .
    

Intervention name(s): Patients' procalcitonin, thrombocyte, and leukocyte levels were assessed every other day for 4 weeks, beginning on the first day they were admitted to the burn center.
Intervention type(s): Diagnostic Test
Intervention description(s): This patients who were included in this study were assessed for four weeks from the first day of hospitalization and taken to the treatment program. All patients who use peripheral venous catheters in this group.
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Diagnostic
Keywords: burns; Blood stream infections; procalcitonin