Effectiveness of Theobromine Toothpaste
Condition: Dental Plaque; Dental Care
MeSH terms: Dental Plaque
Study type: Interventional

Summary: 
      Since plaque control forms the basis for caries prevention, the type of toothpaste and its
      constituents becomes more important.

      Toothpaste containing fluoride are widely popular and fluorides have been historically
      reported to have effects against dental caries. However, the fluoride safe doses are still
      discussed ,because fluoride has toxicity and causing fluorosis.

      The aim of the current research is to find alternative agent that can be used without side
      effects.
    

Detailed description: 
      Participants will be examined to ensure that they have met the smple entrey criteria,then the
      participants will be randomly assigned to four groups each one according to a group:

        1. A group of children using low-fluoridated toothpaste (500ppm)

        2. A group of children using fluoridated toothpaste (1450ppm)

        3. A group of children using theobromine toothpaste (2%)

        4. A group of children using low-fluoridated toothpaste (4%) The researcher will teach the
           participants how to brush using (tell-show-do)technique.

             -  The brushing method that will be used is the fones technique.

             -  Brushing duration must be 2minutes.

             -  Frequency of brushing must be twice a day

             -  The amount of toothpaste used is pea size.

      Mechanism of examination and follow up:

      A thorough scaling and plaque removal was conducted and the children were advised to brush
      their teeth using their regular toothpaste for a week before starting the research.

      Gingival will be evaluated with gingival index (loe and silness)
    

Intervention name(s): Evaluation of the effectiveness of low- fluoridated toothpaste.; Evaluation of the effectiveness of fluoridated toothpaste.; Evaluation of the effectiveness of theobromine toothpaste (2%) toothpaste.; Evaluation of the effectiveness of theobromine toothpaste(4%) toothpaste.
Intervention type(s): Other; Other; Other; Other
Intervention description(s): Children will be given low- fluoridated toothpaste, plaque score in groups will be assess pre given toothpaste in baseline,aweek,2week,and after 3weeks by using the TMQHPI for both buccal and lingual surface.
Gingivalitis will be assess pre given toothpaste,aweek,2weeks,and after 3weeks by using gingival index (loe and silness).; Children will be given e fluoridated toothpaste, plaque score in groups will be assess pre given toothpaste in baseline,aweek,2week,and after 3weeks by using the TMQHPI for both buccal and lingual surface.
Gingivalitis will be assess pre given toothpaste,aweek,2weeks,and after 3weeks by using gingival index (loe and silness).; Children will be given theobromine toothpaste(2%),plaque score in groups will be assess pre given toothpaste in baseline,aweek,2week,and after 3weeks by using the TMQHPI for both buccal and lingual surface.
Gingivalitis will be assess pre given toothpaste,aweek,2weeks,and after 3weeks by using gingival index (loe and silness).; Children will be given theobromine toothpaste(4%),plaque score in groups will be assess pre given toothpaste in baseline,aweek,2week,and after 3weeks by using the TMQHPI for both buccal and lingual surface.
Gingivalitis will be assess pre given toothpaste,aweek,2weeks,and after 3weeks by using gingival index (loe and silness).
Intervention MeSH terms: Theobromine
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary purpose: Prevention
Keywords: Dental Primary Prevention; Theobromine toothpaste; Fluoridated toothpaste