Photobiomodulation for Concussions: the Use of the ImPACT® Test as an Assessment Tool
Condition: Mild Traumatic Brain Injury
MeSH terms: Brain Injuries; Brain Injuries, Traumatic; Brain Concussion
Study type: Observational

Summary: 
      Brain photobiomodulation (PBM) therapy is an innovative modality for the stimulation of
      neural activity in order to improve brain function and is currently under investigation as a
      treatment for several diverse neurological disorders. Our emphasis on this study is to review
      the use of PBM as a treatment modality for concussions and the use of ImPACT® (Immediate
      Post-Concussion Assessment and Cognitive Testing) test to assess improvement in cognition and
      symptomatology in patients with post-concussion syndrome (PCS) treated with PBM.
    

Detailed description: 
      -  This will be a retrospective, single arm, unmasked, clinical study.

        -  Data scores will be collected for patients who initially underwent the Workplace
           Post-Injury 1 test of the ImPACT® test system prior to PBM treatment.

        -  Patients were treated with photobiomodulation using the BIOFLEX® DUO+ system that
           utilized a 180 bulb Light Emitting Diode (LED) array followed by laser probes. Both
           delivery methods were applied to the cervical spine and the cranium, and both entailed
           the use of red light at 660 nm wavelength and near-infrared light at 830-840 nm
           wavelength. Treatment is provided three times per week on alternating days with weekends
           off for 4 weeks for a total of 12 treatments utilizing Health Canada approved device
           specific protocol guidelines for treatment of the cervical spine.

        -  Data scores will be collected for a second ImPACT® test using the Workplace Post-Injury
           2 test.

        -  Results of the Post-Injury 1 test and the Post-Injury 2 test will be compared.
    

Intervention name(s): BIOFLEX DUO+
Intervention type(s): Device
Intervention description(s): Data scores will be collected for patients who initially underwent the Workplace Post-Injury 1 test of the ImPACT® test system prior to PBM treatment.
Patients were treated with photobiomodulation using the BIOFLEX® DUO+ system that utilized a 180 bulb Light Emitting Diode (LED) array followed by laser probes. Both delivery methods were applied to the cervical spine and the cranium, and both entailed the use of red light at 660 nm wavelength and near-infrared light at 830-840 nm wavelength. Treatment is provided three times per week on alternating days with weekends off for 4 weeks for a total of 12 treatments utilizing Health Canada approved device specific protocol guidelines for treatment of the cervical spine.
Data scores will be collected for a second ImPACT® test using the Workplace Post-Injury 2 test.
Results of the Post-Injury 1 test and the Post-Injury 2 test will be compared.
Other intervention name(s): ImPACT test
Observational model: Cohort
Time perspective: Retrospective
Sampling method: Non-Probability Sample
Study population: 
        Data will be collected for all patients diagnosed with post-concussion syndrome who sought
        consult and treated using photobiomodulation therapy at Meditech Rehabilitation Centre
        using the BIOFLEX® DUO+ system
      
Keywords: Concussion, Photobiomodulation, ImPACT