Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic
Condition: Ventilation During Resuscitation
MeSH terms: COVID-19
Study type: Interventional

Summary: 
      Complex practical BLS training have been stopped all over the world due to COVID-19 pandemic
      in 2020. While launching the new Simulation Centre at Medical Faculty of Masaryk University
      in Brno, Czech Republic, teachers and students have been dealing with the risk of COVID-19
      transmission during the simulation training. One of the highest risks for the transfer of
      COVID-19 between the medical students is during the mouth-to-mouth ventilation training in
      BLS.

      It has been assumed that rescuers during BLS simulation training with use of breathable
      nanofiber respirator with layers with accelerated copper can provide efficient mouth-to-mouth
      rescue breaths to the mannequin in compliance with safety rules.
    

Detailed description: 
      The main aim of this study is to assess the efficiency of mouth-to-mouth ventilation through
      breathable self-sterilizing nanofiber respirators with accelerated copper in COVID-19
      pandemic time. 100 volunteers (medical students trained as BLS trainers an medical students
      trained in BLS) will provide 2 minutes cycle of BLS according to European Resuscitation
      Council (ERC) guidelines 2021 wearing the breathable self-sterilizing nanofiber respirators
      with accelerated copper in three different mannequins: Professional Adult Medium Skin CPR-AED
      Training Manikin with CPR Monitor (Prestan), Resusci Anne QCPR AED (Laerdal), Resusci Baby
      QCPR (Laerdal). The mannequin will be utilised in a randomised order. The efficiency of
      mouth-to-mouth rescue breaths as "visible breath " and "not visible breath" will be recorded.
      In first BLS mannequin, the visibility of chest rising by the observer will be recorded. In
      two other mannequins, the ventilation metrics and each rescue breath evaluation in QCPR Skill
      Reporter will be recorded. Overall, 3 levels of visible breath according to the relation to
      set optimal breath volume (400 to 600 mL in adult, 30 to 50 mL in infant): low volume breath
      (below 400ml in adults and below 30ml in infant), optimal volume breath (between 400-600ml in
      adult and between 30-50 ml in infant), high volume breath (over 600ml in adult and over 50ml
      in infant) will be evaluated. For the primary analysis of efficiency of mouth-to-mouth
      ventilation, data from all three mannequins using outcome No breath / Visible breath will be
      evaluated. Secondary analysis will utilize data from two mannequins where detailed
      stratification No Breath / low / optimal / high Visible breath is possible. The mean volume
      of rescue breaths in the 2-minute cycle, average pause, longest pause, success in achieving
      the optimal breath volume, adverse events will be recorded. Regarding the technique of
      provided mouth-to-mouth ventilation, head tilt in adult or neutral position in infant and
      pinching of the nose will be evaluated.
    

Intervention name(s): Mout-to-mouth ventilation; Mout-to-mouth ventilation with quantitative analysis
Intervention type(s): Procedure; Procedure
Intervention description(s): we will record the visibility of chest rising; we will record the visibility of chest rising, review the ventilation metrics and evaluate each rescue breath in QCPR Skill Reporter
Other intervention name(s): Mout-to-mouth ventilation
Allocation: Randomized
Intervention model: Crossover Assignment
Intervention model description: Medical students trained as BLS providers (first group) and Medical student trained as teachers will perform mouth-to-mouth ventilation in 3 case scenarios on 3 different mannequins.
Masking: None (Open Label)
Primary purpose: Other
Keywords: Basic life support; COVID-19; Self-sterilizing nanofiber respirator; Mouth-to-mouth ventilation; Efficiency