Clinical Efficacy of Different Fissure Sealant Materials in the Newly Erupted Non-Carious First Permanent Molars
Condition: Fissure Sealant
Study type: Interventional

Summary: 
      The aim of this study is to compare the clinical retention rates, marginal adaptation,
      marginal discoloration and secondary caries formation of two different types of
      resin-modified glass ionomers (Fuji® II LC; Clinpro™ XT Varnish) and giomer-containing
      fissure sealant materials (Beautifil Flow) with glass ionomer-containing fissure sealant
      material (Fuji Triage®) used on newly erupted non-carious first permanent molars as a fissure
      sealant.

      The study included 384 teeth belonging to 182 children, aged between 5 to 9 years old, who
      have two newly erupted mandibular permanent first molars.
    

Detailed description: 
      Firstly, patients were randomly allocated to three main groups: Group 1; Fuji II LC/Fuji
      Triage (Control) (62 patients), Group 2; Clinpro XT Varnish/Fuji Triage (Control) (60
      patients), Group 3; Beautifil Flow/Fuji Triage (Control) (60 patients). After clinical
      applications, all samples were evaluated in terms of retention, marginal adaptation, marginal
      discoloration and secondary caries formation using modified USPHS criteria in 6th, 12th and
      18th months. Also samples were evaluated in terms of remineralization effect using the laser
      fluorescence method. Evaluations on occlusal and buccal surfaces were performed separately.
    

Intervention name(s): Fuji® II LC CAPSULE; Clinpro™ XT Varnish; Beautifil Flow; Fuji Triage® CAPSULE
Intervention type(s): Device; Device; Device; Device
Intervention description(s): Fuji® II LC is a resin modified glass ionomer contained, fluoride releasing and light-cured material. Since the product is tolerant to moisture and saliva, it's used for fissure sealant of newly erupted teeth.
Test 1 newly erupted first permanent molars were cleaned with a pumice paste using a bristle brush and isolated with cotton rolls. Then, 20% cavity conditioner was applied to all surfaces of the tooth for 10 seconds.The tooth surface was rinsed with water and dried. Thereafter, Fuji® II LC was applied to the pits and fissures on the tooth surface using a brush. Then, the varnish was applied and cured according to the manufacturer's instructions.; Clinpro™ XT Varnish is a resin modified glass ionomer containing, fluoride-releasing, light-cured varnish. Since the product is tolerant to moisture and saliva, it is used for fissure sealant of newly erupted teeth. The product can be recharged with fluoride using fluoride-containing products.
Test 2 newly erupted first permanent molars were cleaned with a pumice paste using a bristle brush and isolated with cotton rolls. Then, 35% phosphoric acid was applied to all surfaces of the tooth for 15 seconds.Then the tooth surface was rinsed with water and dried. Thereafter, Clinpro™ XT Varnish was applied in compliance with the manufacturers' instructions.; Beautiful Flow is a Giomer contained, fluoride releasing and light cured material. The product contains pre-reacted glass ionomer particles (PRG). It is a high water resistant material. It is used for fissure sealant.
Test 3 newly erupted first permanent molars were cleaned with a pumice paste using a bristle brush and isolated with cotton rolls. Then, 7% phosphoric acid was applied to all surfaces of the tooth for 10 seconds. Then the tooth surface was rinsed with water and dried. Afterwards, a two-stage self-etch adhesive system was applied. Thereafter, Beautiful Flow was applied in compliance with the manufacturers' instructions.; Fuji Triage® is a new generation glass ionomer containing with low viscosity, high fluoride content and light curing materials. Since the product is tolerant of moisture and saliva, it is used for fissure sealant of newly erupted teeth.
Control newly erupted first permanent molars were cleaned with a pumice paste using a bristle brush and isolated with cotton rolls. Then, 20% cavity conditioner was applied to all surfaces of the tooth for 10 seconds.Then the tooth surface was rinsed with water and dried. Thereafter,Fuji Triage® was applied to the pits and fissures on the tooth surface using a brush. Thereafter, the varnish was applied and cured according to the manufacturer's instructions.
Other intervention name(s): Fuji® II LC CAPSULE, GC Corporation, Tokyo, Japan; Clinpro™ XT Varnish, 3M ESPE, St. Pauls, Miniapolis, MN, USA; Beautifil Flow, Shofu, Kyoto, Japan; Fuji Triage® CAPSULE, GC Corporation, Tokyo, Japan
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: randomized controlled, three-arm parallel, single-blinded, split-mouth clinical trial
Masking: Double (Participant, Outcomes Assessor)
Primary purpose: Treatment
Keywords: Conventional glass ionomer; fissure sealant; giomer; laser fluorescence; newly erupted teeth; resin modified glass ionomer