Evaluation of Carpal Tunnel Syndrome in Pregnancy
Condition: Carpal Tunnel; Carpal Tunnel Syndrome
MeSH terms: Carpal Tunnel Syndrome; Syndrome
Study type: Observational

Summary: 
      Carpal tunnel syndrome (CTS) is a condition that happens when the median nerve in the wrist
      gets compressed, causing pain, numbness, and tingling in the hand and fingers. It's a common
      condition that affects between 3% and 6% of people in the general population.

      During pregnancy, CTS can be a bigger problem because hormonal changes can cause swelling and
      put more pressure on the median nerve. Studies show that CTS can affect up to 45% of pregnant
      women, making it important to identify and manage.

      CTS can be diagnosed through a physical exam by a doctor, who will check for symptoms like
      pain, tingling, or weakness in the hand and fingers. Ultrasound can also be used to diagnose
      CTS by measuring the size of the median nerve in the wrist. This is a non-invasive imaging
      technique that is generally considered reliable for diagnosing CTS.

      In previous studies, ultrasound has been used to measure the size of the median nerve in
      pregnant women with carpal tunnel syndrome (CTS). However, a new ratio of median nerve
      cross-sectional area to flexor carpi radialis cross-sectional area (MN-CSA/FCR-CSA) has not
      been studied in pregnant women. This ratio may be a more sensitive diagnostic tool for CTS
      because it is not affected by swelling, which is a common symptom during pregnancy that can
      affect the size of the median nerve.
    

Detailed description: 
      Carpal tunnel syndrome (CTS) is a condition that arises due to the compression of the median
      nerve in the carpal tunnel of the wrist. The prevalence of CTS in the general population is
      estimated to be between 3% and 6%, with higher rates in certain occupations or activities
      that involve repetitive hand movements or vibrations.

      During pregnancy, CTS can be particularly important due to hormonal changes that can cause an
      increase in fluid retention and pressure on the median nerve. The prevalence of CTS during
      pregnancy varies widely in the literature, with some studies reporting rates as high as 45%.

      Ultrasound is a non-invasive imaging technique that can be used to diagnose CTS by measuring
      the cross-sectional area of the median nerve. While there is some debate regarding the
      normative values of median nerve cross-sectional area, ultrasound is generally considered a
      reliable diagnostic tool for CTS.

      Previous research has utilized ultrasound to measure the cross-sectional area of the median
      nerve (MN-CSA) in pregnant women diagnosed with carpal tunnel syndrome (CTS). However, the
      potential diagnostic value of the MN-CSA/flexor carpi radialis cross-sectional area (FCR-CSA)
      ratio has not been examined in this population. Given that edema, a common symptom of
      pregnancy, may affect MN-CSA but not MN-CSA/FCR-CSA ratio, this novel ultrasound parameter
      may offer superior sensitivity for diagnosing CTS in pregnant women.
    

Intervention name(s): Evaluation of median nerve with ultrasound
Intervention type(s): Diagnostic Test
Intervention description(s): ultrasound examination wrist
Observational model: Case-Control
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        CTS in pregnancy
      
Keywords: pregnancy; carpal tunnel syndrome