HAptic Neurofeedback Design for Stroke
Condition: Stroke
MeSH terms: Stroke
Study type: Interventional

Summary: 
      Interventional study with minimal risks and constraints, prospective, monocentric.
    

Detailed description: 
      Many patients with stroke have a severe motor deficit in the upper limb impacting their
      independence. Electroencephalogram (EEG) Neurofeedback is a re-education technique that
      improves cerebral plasticity and motor gain in these people during the chronic phase of
      stroke. The visual feedback usually used tends to diminish the subject's attentional
      resources, while the proprioceptive feedbacks appear to be more effective on cortical
      excitability. Vibration feedback inducing movement illusion has been shown to be effective in
      healthy subjects, but has not been tested in people with stroke.
    

Intervention name(s): Visual virtual Conditions; Standard EEG; Neurofeedback Training Stroke Patients
Intervention type(s): Other; Other; Other
Intervention description(s): The objective is to evaluate if certain virtual visual conditions can increase the illusion of movement induced by the tendon vibration of the upper limb.
Thirty healthy volunteers and 20 post-stroke subjects will test 3 different situations of vibration applications, with no EEG Neurofeedback session. It will be applied to the subject (healthy and post-stroke) according to a randomized order a vibrator for a few minutes on his non-dominant (or deficit) hand hidden from view, with a screen representing a static virtual hand, then a vibrator on his hand hidden with a screen representing an animated virtual hand, then a vibrator on his hand hidden with a screen representing an empty background.; Twenty healthy volunteers test 3 separate electroencephalographic recording conditions without Neurofeedback. It will be applied to the subject an EEG headset recording brain activity during the application of vibration stimulation producing the illusion of movement on the non-dominant hand or during a task Mental imagery of the upper limb, or during the joint application of vibratory stimulation and a mental imaging task on the affected upper limb in a randomized order.; The post-stroke subject is evaluated on clinical tests (FMA, ARAT, MAL, NHPT, Finger Tapping test) during the first visit. Then, he performs 12 sessions of NFB (on his deficit member) lasting 45 minutes, spread over 6 weeks, depending on the feedback modality that has been drawn randomly (visual or visuo-vibratory). A second visit after the first NFB session and a third visit after the last NFB session evaluates the motor skills of the trained upper limb (FMA, ARAT, MAL, NHPT, Finger Tapping test) and a satisfaction questionnaire is given to the subject for evaluate tolerance and satisfaction with the feedback modality assigned. Evaluation of changes of EEG sensorimotor rhythms at the end of the program.
Other intervention name(s): 3 different situations of vibration applications, without EGG neurofeedback session; 3 separate electroencephalographic recording conditions without Neurofeedback; 12 neurofeedback sessions spread over 6 weeks according to the feedback modality that will be drawn (visual or visuo-vibratory)
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Other
Keywords: stroke; neurofeedback; tendon vibration; virtual reality; haptic