Composition for Treating Cirrhosis and Liver Cancer (SB-1121)
Condition: Cirrhosis of the Liver
MeSH terms: Liver Neoplasms; Liver Cirrhosis; Fibrosis
Study type: Interventional

Summary: 
      The composition treats cirrhosis and hepatocellular carcinoma (Hcc) at an early stage. The
      product is extracted from herbs, including Adenosma glutinosum extract, Eclipta prostrata
      extract, Phyllanthus urinaria extract, Impatiens balsamina extract, Ascorbic acid, pyridoxine
      5-phosphate, L-Arginine hydrochloride, Pregnenolone acetate. These components have
      participated in repairing and regenerating new liver parenchyma, preventing fibrosis cell
      generation, preventing liver cancer cell growth at an early stage. The composition
      supplements precursors which help the body strengthen antibodies and reduce the risk of
      inflammation, restore physiological and biochemical functions of liver cells after chronic
      inflammation.
    

Detailed description: 
      The composition is fractionally extracted from herbs. Flavonoids, isoflavonoids, and
      pregnenolone combined with ascorbic acid, pyridoxine 5-phosphate, L-arginine act as the key
      compounds in the regeneration of fibrosis liver cells, remove scar tissue, stimulate and
      release growth hormones, prevent progression to Hcc and prevent Hcc recurrence.

      The pharmaceutical ingredients involved in the composition are calculated to increase their
      effectiveness in preventing and curing cirrhosis and Hcc.

      Currently, many preparations have been and are being studied to fight against cirrhosis and
      liver cancer globally. The effectiveness of this preparation is a new finding which has been
      proven over 5 years of follow-up.

      Pregnenolone is a cortisol precursor. Cortisol plays an important role in several systems in
      the body, including the immune system(in the cycle of the immune system to produce B
      lymphocytes). This ingredient is used as a supplement to stabilize the endothelium, regulate
      the amount of cortisol within normal limits, and help the body produce B lymphocytes with a
      good response.

      Kaempferol is a flavonoid that participates in cell protection against toxic proteins which
      were produced during prolonged inflammation; blocking the action and removing denatured
      proteins that change the parenchyma of liver cells. The selected flavonoids repaired the
      fibrotic structure of liver parenchyma after chronic inflammation. Ascorbic acid, pyridoxine
      5-phosphate, and L-arginine help to facilitate biological functions in cell adhesion,
      synergize with flavonoids in cell membrane protection, structural repair, and liver cell
      regeneration.

      Ascorbic acid, pyridoxine 5-phosphate act as enzymes that catalyze processes conveniently.
    

Intervention name(s): SB-1121(1); SB-1121(2)
Intervention type(s): Drug; Drug
Intervention description(s): The daily maintenance, SB-1121(1) dose is to take 2 times a day, 1 tablet each time.; The daily maintenance, SB-1121(2) dose is to take 2 times a day, 1 tablet each time.
Other intervention name(s): Cirrhosis/SB-1121; Cirrhosis/Hcc/SB-1121
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Participant)
Primary purpose: Treatment
Keywords: Liver; Cirrhosis; Hcc; Flavonoids; Pregnenolone; Ascorbic acid; B6