Carbohydrate-Protein Supplementation During Endurance Running
Condition: Supplementation During Endurance Performance
Study type: Interventional

Summary: 
      The purpose of this study is to assess whether the greater performance benefits from
      ingesting carbohydrate-protein supplements during endurance running, in comparison to the
      traditionally used carbohydrate supplement, is attributed to the extra calories contained in
      the carbohydrate-protein supplement or the presence of protein.
    

Detailed description: 
      The purpose of this study is to determine whether the performance benefits from consuming a
      carbohydrate-protein (CHO-P) supplement, such as Accelerade, during endurance exercise, as
      opposed to the traditionally used carbohydrate (CHO) supplement, such as Gatorade, are
      attributed to the extra calories in the CHO-P supplement or the presence of protein alone in
      comparison to CHO supplements. Numerous studies comparing CHO and CHO-P supplements on
      endurance performance have found contradicting results in terms of CHO-P supplementation and
      performance benefits. While physiological mechanisms have been proposed as to why the CHO-P
      supplements elicit greater performance, research has yet to determine why some studies have
      found this, especially while other studies have found no performance benefits from CHO-P
      supplementation. This inconsistency in research may be due to the caloric difference between
      supplements tested; due to the addition of protein, the CHO-P supplement contains more
      calories per serving than the CHO supplement. As a result, this study will be comparing 4
      different supplements during endurance exercise, a CHO-P supplement, CHO supplement, a double
      carbohydrate supplement (CHO-CHO), and a placebo (PLA). The CHO and CHO-P supplement will be
      matched for CHO content, whereas the CHO-P and CHO-CHO supplements will be matched for total
      caloric content. Participants will be asked to run four 12-mile runs on 4 separate occasions,
      approximately 7-10 days apart, and will be blinded to supplement content and order of
      supplement administration among trials. The 12-mile run will elicit an exercise bout greater
      than 60 minutes, which is relevant when supplementing exercise with CHO or CHO-P. Performance
      will be assessed via time it takes to complete both the 12-mile run and the 1.6 mile maximal
      effort at the end of the run.
    

Intervention name(s): CHO, CHO-P, CHO-CHO, PLA; CHO-P, CHO-CHO, PLA, CHO; CHO-CHO, PLA, CHO, CHO-P; PLA, CHO, CHO-P, CHO-CHO
Intervention type(s): Dietary Supplement; Dietary Supplement; Dietary Supplement; Dietary Supplement
Intervention description(s): The CHO supplement will be administered during trial 1. The CHO-P will be administered during trial 2. The CHO-CHO supplement will be administered during trial 3. The PLA supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.; The CHO-P supplement will be administered during trial 1. The CHO-CHO will be administered during trial 2. The PLA supplement will be administered during trial 3. The CHO supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.; The CHO-CHO supplement will be administered during trial 1. The PLA will be administered during trial 2. The CHO supplement will be administered during trial 3. The CHO-P supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.; The PLA supplement will be administered during trial 1. The CHO will be administered during trial 2. The CHO-P supplement will be administered during trial 3. The CHO-CHO supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.
Intervention MeSH terms: Prednisone; Prednisolone; Cyclophosphamide; Doxorubicin; Vincristine
Allocation: Randomized
Intervention model: Factorial Assignment
Masking: Single (Participant)
Primary purpose: Other
Keywords: carbohydrate-protein; endurance exercise; supplement