Method of Early Diagnosis of Laryngopharyngeal Reflux
Condition: Laryngopharyngeal Reflux; Laryngopharyngitis Chronic; Gastro Esophageal Reflux; Laryngitis
MeSH terms: Laryngitis; Gastroesophageal Reflux; Laryngopharyngeal Reflux; Croup
Study type: Interventional

Summary: 
      The investigator will issue a Patient Information Consent for the participant in the study.
      1.Patients will be asked to complete the Reflux Symptom Index questionnaire.

      Clinical survey, medical history. 2. Objective methods for assessing the patient's condition:

      - examination of ENT organs. 3. Laboratory and instrumental research methods: Endoscopic
      laryngoscopy and video laryngoscopy, pH-metry, acoustic voice analysis.

      4.Sociological method. 5. Subjective methods for assessing the condition of the larynx. 6.
      Аnalysis of the received data
    

Detailed description: 
      The investigator will issue a Patient Information Consent for the participant in the study.
      1.Patients will be asked to complete the Reflux Symptom Index questionnaire.

      Clinical survey, medical history 2. Objective methods for assessing the patient's condition:

      - examination of ENT organs: rhinoscopy, otoscopy, pharyngoscopy and laryngoscopy 3.
      Laboratory and instrumental research methods - Endoscopic laryngoscopy and video
      laryngoscopy. pH-metry: The collection of mucus from the laryngopharynx for the determination
      of acid-base values. Acoustic voice analysis: objective assessment of the voice condition
      4.Sociological method: determination of lifestyle, nutrition, the presence or absence of bad
      habits.

      5. Subjective methods for assessing the condition of the larynx - Questionnaires.

      6. Аnalysis of the received data
    

Intervention name(s): pH metry; Filling out the questionnaire; Endoscopic laryngoscopy; Acoustic voice analysis
Intervention type(s): Diagnostic Test; Diagnostic Test; Device; Device
Intervention description(s): The collection of mucus from the laryngopharynx to determine the acid-base values through pH-metry.; Completion of the questionnaire index of reflux symptoms. An analysis of the results of the effectiveness of this method in patients with complaints of sore throat, coughing, burning sensation in the throat, cough, frequent sore throat, difficulty swallowing, lump in the throat, feeling of a foreign body in the throat, voice change, heartburn, belching will be carried out. Evaluation results range from 0 to 5, where 0 is an indicator of no problem, and 5 is an indicator of a serious problem; Video laryngoscopy and assessment of the presence / severity of the symptoms. Evaluation results range from 0 to 4, where 0 is an indicator of no problem, and 4 is an indicator of a serious problem; acoustic analysis of the voice was performed in singers with voice disorders before and after treatment using program of the Lingwaves
Allocation: Non-Randomized
Intervention model: Parallel Assignment
Masking: None (Open Label)
Primary purpose: Diagnostic
Keywords: Laryngopharyngeal Reflux; Laryngopharyngitis Chronic; Gastro Esophageal Reflux; Laryngitis; pH monitoring; pH metric; acoustic voice analysis