Maximal Exercise Capacity and Extra-pulmonary Characteristics in Patients With Lung Cancer With Complete Remission .
Condition: Lung Cancer
MeSH terms: Lung Neoplasms
Study type: Observational

Summary: 
      While lung cancer are rare disease in the early 20th century, its incidence increased in
      parallel with the increase in smoking habits. It is the most common type of cancer in the
      world. Despite advances in the efficacy of chemotherapy and radiotherapy regimens, surgical
      resection is the most effective curative treatment modality to improve survival in non-small
      cell lung cancer. Pulmonary resection candidates are selected according to not only tumor
      type and stage, but also functional status, exercise capacity, underlying lung disorders and
      health-related quality of life assessments. Patients with lung cancer often have lung and
      heart comorbidities that affect the outcome of the outcome measures and restricts cancer
      treatment options. In patients with lung cancer, shortness of breath, physical inactivity,
      weakness in peripheral muscles and exercise intolerance are described. Pulmonary
      rehabilitation is a multidisciplinary treatment designed to improve exercise capacity,
      functional status, health-related quality of life and to reduce the attenuation of chronic
      shortness of breath and fatigue in patients with chronic lung problems.

      In literature, the effect of surgery in patients with lung cancer on postoperative
      respiratory muscle strength is not clear. There is no study investigating the effect of
      chemotherapy and radiotherapy on respiratory muscle strength. For these reasons, the aim of
      the study was to evaluate the curative period of non-small cell lung cancer patients with
      reliability and validity assessment methods. The hypothesis of our study was; when compared
      with patients with lung cancer and healthy individuals, exercise capacity, respiratory and
      peripheral muscle strength, physical activity levels, sleep and quality of life of lung
      cancer patients are reduced; dyspnoea, fatigue, depression, cough and pain levels increase.
    

Detailed description: 
      According to sample size calculation 20 lung with complete remission cancer patients and 20
      healthy individuals were included in the study. Cross-sectional observational research. The
      demographic, physical and physiological characteristics were recorded from the patient files.
      Exercise capacity (using cardiopulmonary exercise testing), physical activity, pulmonary
      functions, respiratory and peripheral muscle strength, dyspnea and fatigue perception,
      depression, cough, pain and quality of life were evaluated. Primary outcome measurement is
      maximal exercise capacity. Secondary outcomes are respiratory and peripheral muscle strength,
      pulmonary functions, physical activity, dyspnea and fatigue perception, depression, cough,
      pain and quality of life.
    

Observational model: Case-Control
Time perspective: Other
Sampling method: Non-Probability Sample
Study population: 
        20 patients with lung cancer were included in the patients group and 20 healthy individuals
        were included in the control group
      
Keywords: Lung cancer; Exercise capacity; Cardiopulmonary exercise test; Respiratory muscle strength; Physical activity; Pulmonary functions; Peripheral Muscle Strength; Quality of life; Sleep of quality; Dyspnea; Depression; Fatigue; Cough