The Effect of Nursing Education on Oral Mucositis in Bone Marrow Transplant Patients
Condition: Blood Stem Cell Transplant Failure; Oral Mucositis; Nurse's Role
MeSH terms: Mucositis; Stomatitis
Study type: Interventional

Summary: 
      In this study, it is aimed to examine the effect of oral care training for oral mucositis,
      which will be given by the researcher to patients who have undergone bone marrow
      transplantation, on the incidence and severity of oral mucositis in patients. The aim of the
      study is to be carried out in a public and private hospital in Antalya province, in two
      different hospitals with a public and private status, and with a total of 60 patients, 30 of
      which are in the experimental group and 30 in the control group. In the study, "oral care
      training for oral mucositis" and "oral mucositis follow-up procedure" will be developed by
      the researcher for bone marrow transplant patients. Bone marrow transplant patients will be
      educated and followed up according to the follow-up procedure before starting the
      chemotherapy regimen treatments planned before the transplant.
    

Detailed description: 
      Type of study: It was designed as a randomized controlled experimental study.

      Location and Characteristics of the Research:

      With the application for the Permission of the Research Ethics Committee, the official
      institution permission process was started and the Medstar Antalya Hospital was approved by
      Prof. Dr. It is planned to be performed in İhsan Karadoğan Bone Marrow Transplantation unit
      and in the Adult Bone Marrow Transplantation Unit of Akdeniz University Medical Faculty
      Hospital. prof. Dr. İhsan Karadoğan bone marrow transplant unit has a total of 19 beds and 16
      KIT nurses work. There are 12 patient beds and 11 KIT nurses work in the Adult Bone Marrow
      Transplant Unit of Akdeniz University Medical Faculty Hospital. In both units, the rooms have
      a positive pressure system, air filtration is provided with the hepafilter system, it works
      with private rooms and a system of having only one attendant.

      Population and Sample of the Research:

      The population of the study will consist of individuals over 17 years of age, who are
      hospitalized in the relevant clinics and have been decided to have a bone marrow transplant,
      who can speak Turkish and who have no communication barriers, who are prepared for
      transplantation, and who do not have oral mucositis in their mouths. The research sample will
      consist of patients who have these characteristics and agree to participate in the study.
      Patients will be randomly assigned to the experimental and control groups.

      The targeted situation with this study; The aim of the study is to reduce the development of
      intraoral infections due to the decrease of immune resistance of the patients after the
      transplantation with the effect of the chemotherapy treatment given before the transfer of
      the nurse training given for oral mucositis or the degree of the developing oral mucositis,
      the severity of the pain, its effect on nutrition, speech and swallowing power. Another goal
      of this study is to enable patients to know the effects of oral mucositis that may develop
      during the transplant process and to manage this process effectively.

      Analysis of Data:

      The analysis of the obtained data will be evaluated with SPSS 20.0 package programs. The
      normal distribution of the data will be checked with the Shapiro-Wilk test. Independent
      two-sample t-test will be used to compare normally distributed data, and Manny-Whitney U-test
      will be used for non-normally distributed data. In the comparison of the pre-test and
      post-test data of the experimental (educational) and control groups, dependent sample t-test
      will be used for normally distributed variables, and Wilcoxon t-test will be used for
      non-normally distributed variables. Chi-square (X2) test exact values will be used in the
      comparison of categorical variables. The relationships of continuous data will be looked at
      with Spearman's rho correlation analysis. Statistical significance level will be accepted as
      p<0.05 in all analyzes.
    

Intervention name(s): Oral mukositis nurse's education for patients
Intervention type(s): Other
Intervention description(s): Education given to patients by nurses on the prevention, treatment and care of oral mucositis
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: This is a randomized controlled trial. Oral mucositis levels of patients treated in hospital for bone marrow transplantation will be examined. Before starting the research, permission will be obtained from the patients, and after the necessary randomization, they will be assigned to the experimental and control groups. The patients in the experimental group will be trained for oral mucositis. Oral diagnosis of the patients will be made once a week for four weeks and the effectiveness of the nursing education given to the patients will be evaluated.
Masking: Single (Participant)
Primary purpose: Health Services Research
Keywords: Blood Stem Cell Transplantation; Oral Mucositis; Nurse Education for Patients