Cupping Therapy on Immune System in Post Covid -19
Condition: Covid-19 Patients
MeSH terms: COVID-19
Study type: Interventional

Summary: 
      Purpose of this study is to investigate

        1. The effect of Dry cupping therapy on T-Lymphocyte in post covid-19 patients.

        2. The effect of Dry cupping therapy on serum Cytokine in post covid-19 patients.

        3. The effect of Dry cupping therapy on Immunoglobulin IgA.

        4. The effect of Dry cupping therapy on Immunoglobulin IgM.

        5. The effect of Dry cupping therapy on Immunoglobulin IgG. seventy six patients of both
           genders with deficiency in T-Lymphocyte number,,higher level of serum cytokine and lower
           immunoglobulin IgA,IgM,IgG after two weeks of recovery from covid-19 . Age range from
           Twenty one to Sixty six years old .They participated in the study and recruited from
           surveillance unit of Shobra general hospital .These patients recruited by phone and have
           been offered to participate in the programme.The patients were divided equally into two
           groups (A and B). Assessment was done before and after treatment. T-Lymphocyte, serum
           cytokine and immunoglobulin IgA, IgM and IgG were analyzed by kenza 240 TX from
           fluorescence-labeled flow cytometry. Disposable cupping therapy instrument was used in
           treatment of group (A) in addition to traditional medical treatment in the form of
           vitamin C, D and anticoagulant drugs. Traditional medical treatment only was used in
           treatment of group (B).The obtained results of this study will determine the significant
           improvement of participated two groups.

           .
    

Detailed description: 
      Patient were selected randomly and distributed in two groups by computer generation. The
      sample size was calculated using the G*Power software (version 3.0.10). F-test MANOVA within
      and between interaction effects was selected. Considering a power of 0.80, an α level of 0.05
      (2 tailed) and effect size of 0.39; two groups and response variables of five, a generated
      sample size of at least 38 participants per group was required and total sample size of 76
      subjects.
    

Intervention name(s): Cupping therapy with convential medical treatment; Convential medical treatment
Intervention type(s): Combination Product; Drug
Intervention description(s): Device:Cupping therapy device
Group A participants received Dry cupping therapy one session per week for 8 weeks with 6 days intervals between sessions and with cups applied to the skin for around 8 minutes. (In addition to convential medical treatment for 8 weeks in the form of :
Vitamin D: The recommended dietary dose of vitamin D is 600 IU each day for adults 70 and younger .
Vitamine C: The recommended dietary dose 200 mg/day vitamin c
Anticoagulation drugs ("blood thinners")Doctors usually prescribe low-molecular-weight heparin (enoxaparin) (30 mg), each given subcutaneously every 12 hours .; Group B participants received convential medical treatment for 8 weeks in the form of :
Vitamin D: The recommended dietary dose of vitamin D is 600 IU each day for adults 70 and younger .
Vitamine C: The recommended dietary dose 200 mg/day vitamin C
Anticoagulation drugs ("blood thinners")Doctors usually prescribe low-molecular-weight heparin (enoxaparin) (30 mg), each given subcutaneously every 12 hours .
Allocation: Randomized
Intervention model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary purpose: Treatment