Patient and Partner Perception After Remission of Cushing's Syndrome
Condition: Hypercorticism
MeSH terms: Cushing Syndrome; Adrenocortical Hyperfunction
Study type: Observational [Patient Registry]

Summary: 
      Hypercortisolism leads to long term physical and cognitive sequelae. This also holds true for
      quality of life, even several years after remission. This altered quality of life, highly
      subjective, is however, badly evaluated by the family of the patient. This could lead to
      misunderstanding, avec worsen the general physical and mental health of the patient. To our
      knowledge, this theoretical difference of perception has never been evaluated up to now.

      The aim of our study is to evaluate the difference of perception of the quality of life and
      body image between patients in remission of hypercortisolism, and their caregivers. Secondary
      objectives will be to evaluate the quality of life of the caregivers, the coping strategies,
      and the depression/anxiety parameters of both the patient and the caregiver. Patients and
      methods: the study is Observative, prospective and non-randomized. Inclusion criteria will be
      patients, aged more than 18, with hypercortisolism in remission for at least 1 year.
      Self-questionnaires on quality of life, body image, coping, depression and anxiety will be
      provided to the patient and his/her caregiver. Fulfilling will be blind between the patient
      and his/her caregiver. Inclusion period will be 12 months.

      Results will be compared between the patient and his/her caregiver. Expected results:
      investigators anticipate that some caregivers will have a different perception of the general
      physical and mental condition as stated by the patient. The first time that the quality of
      life of the caregiver would be also altered.

      This original project might lead to modify the management of Cushing's syndrome, by
      considering both the patient and his/her caregiver on a long term basis after remission.
    

Detailed description: 
      Introduction: Hypercortisolism leads to long term physical and cognitive sequelae. This also
      holds true for quality of life, even several years after remission. This altered quality of
      life, highly subjective, is however, badly evaluated by the family of the patient. This could
      lead to misunderstanding, avec worsen the general physical and mental health of the patient.
      To our knowledge, this theoretical difference of perception has never been evaluated up to
      now. Aims: The aim of our study is to evaluate the difference of perception of the quality of
      life and body image between patients in remission of hypercortisolism, and their caregivers.
      Secondary objectives will be to evaluate the quality of life of the caregivers, the coping
      strategies, and the depression/anxiety parameters of both the patient and the caregiver.
      Patients and methods: the study is Observative, prospective and non-randomized. Inclusion
      criteria will be patients, aged more than 18, with hypercortisolism in remission for at least
      1 year. Self-questionnaires on quality of life, body image, coping, depression and anxiety
      will be provided to the patient and his/her caregiver. Fulfilling will be blind between the
      patient and his/her caregiver. Inclusion period will be 12 months. Results will be compared
      between the patient and his/her caregiver. Expected results: investigators anticipate that
      some caregivers will have a different perception of the general physical and mental condition
      as stated by the patient. The first time that the quality of life of the caregiver could be
      also altered. Perspectives: This original project might lead to modify the management of
      Cushing's syndrome, by considering both the patient and his/her caregiver on a long term
      basis after remission.
    

Intervention name(s): Questionnaires of life quality for patients; Questionnaires of life quality for caregivers
Intervention type(s): Other; Other
Intervention description(s): the WhoQoL
a specific scale of Cushing's syndrome
The Beck II scale
HAD scale
Rosenberg questionnaire
Stunkard, Sorensen and Schlusinger (1983) figurines
Brief Cope scale; the WhoQoL
The Beck II scale
HAD scale
Observational model: Cohort
Time perspective: Prospective
Sampling method: Non-Probability Sample
Study population: 
        patients, aged more than 18, with hypercortisolism in remission for at least 1 year.