The Effect of Lidocaine and Benzocaine on Pain and Injection Satisfaction in Peripheral Intravenous Catheter Application
Condition: Peripheral Intravenous Catheterization Application
Study type: Interventional
Phase: Phase 3

Summary: 
      Objective: This research was conducted as a randomized controlled, double-blind experimental
      study to determine the effect of topical lidocaine and benzocaine on patient's pain and
      injection satisfaction before peripheral intravenous catheter application.

      Study Design: The study was completed with 120 individuals who were treated in the green area
      of a University Hospital Emergency Service and met the inclusion criteria of the study. In
      collecting research data; Case Report Form (ORF), Baseline Algometer (66 Lb / 30 Kg) and
      Informed Consent Form were used. Lidocaine Spray, Benzocaine Spray and Alcohol were used in
      research groups.
    

Detailed description: 
      Objective: This research was conducted as a randomized controlled, double-blind experimental
      study to determine the effect of topical lidocaine and benzocaine on patient's pain and
      injection satisfaction before peripheral intravenous catheter application.

      Study Design: The study was completed with 120 individuals who were treated in the green area
      of a University Hospital Emergency Service and met the inclusion criteria of the study.
      Ethics committee approval, Turkey Pharmaceuticals and Medical Devices Agency clinical
      research permission, institutional permission and written informed consent from individuals
      were obtained in the study. In collecting research data; Case Report Form (ORF), Baseline
      Algometer (66 Lb / 30 Kg) and Informed Consent Form were used. Lidocaine Spray, Benzocaine
      Spray and Alcohol were used in research groups. Private health insurance was provided for all
      patients included in the study for complications arising from the procedure. The data
      obtained from the research were evaluated in computer environment using IBM SPSS Statistics
      23.0 statistics package program.
    

Intervention name(s): Lidocaine Spray; Benzokain Sprey; Alcohol
Intervention type(s): Drug; Drug; Other
Intervention description(s): Individuals who met the research criteria and signed the informed consent form were numbered according to the order in which they came to the hospital. Later, the numbered individuals were assigned to the study groups according to the randomization list created in the computer environment.
Lidocaine Spray was applied 60 seconds before to the area where the peripheral intravenous catheter application of the patients in the Experiment I Group (Lidocaine Spray) will be performed. After waiting 60 seconds, peripheral intravenous catheter application was performed.
The nurse responsible for data collection measured blood pressure, pulse rate and peripheral oxygen saturation values 5 minutes before and just after the application with a finger-type pulse oximeter.
After performing peripheral intravenous catheterization, the pain level felt by the individual during the procedure and the injection satisfaction level values were taken and recorded on the Case Report Form by the nurse.; Individuals who met the research criteria and signed the informed consent form were numbered according to the order in which they came to the hospital. Later, the numbered individuals were assigned to the study groups according to the randomization list created in the computer environment.
Benzocaine Spray was applied 60 seconds before to the area where the peripheral intravenous catheter will be applied to the patients in the Experiment II Group (Benzocaine Spray). After waiting 60 seconds, peripheral intravenous catheter application was performed.
The nurse responsible for data collection measured blood pressure, pulse rate and peripheral oxygen saturation values 5 minutes before and just after the application with a finger-type pulse oximeter.
After performing peripheral intravenous catheterization, the pain level felt by the individual during the procedure and the injection satisfaction level values were taken and recorded on the Case Report Form by the nurse.; Individuals who met the research criteria and signed the informed consent form were numbered according to the order in which they came to the hospital. Later, the numbered individuals were assigned to the study groups according to the randomization list created in the computer environment.
In patients in the placebo group, alcohol was sprayed 60 seconds before the area where the peripheral intravenous catheter will be applied. After waiting 60 seconds, peripheral intravenous catheter application was performed.
The nurse responsible for data collection measured blood pressure, pulse rate and peripheral oxygen saturation values 5 minutes before and just after the application with a finger-type pulse oximeter.
After performing peripheral intravenous catheterization, the pain level felt by the individual during the procedure and the injection satisfaction level values were taken and recorded on the Case Report Form by the nurse.
Intervention MeSH terms: Lidocaine
Allocation: Randomized
Intervention model: Factorial Assignment
Intervention model description: During the data collection, 120 individuals who met the inclusion criteria and were selected with the randomization list created on the computer constituted the sample of the study.
Masking: Single (Participant)
Primary purpose: Prevention
Keywords: Peripheral intravenous catheterization; pain; injection satisfaction; pharmacological method; lidocaine; benzocaine