Effects of 12- Weeks of Quantitative Weight-bearing Progressive Resistance Exercise Training on Glycemia Control and Improving Muscle Strength With Type 2 Diabetes Combine Pre-sarcopenia.
Condition: Twelve Week Quantitative Weight Bearing of Resistance Training Effect on Glycemic Control and Muscle Strength
MeSH terms: Sarcopenia; Body Weight
Study type: Interventional

Summary: 
      According to the International Diabetes Federation (IDF) in 2017 investigator found that the
      incidence of type 2 diabetes is currently 425 million people aged 20 to 79 in the world, and
      this data will increase o 629 million at 2045, The etiology of more than 90% is related to
      aging, it has become a serious challenge to public health.

      Sarcopenia is a newly noticed severe syndrome characterized by reduced walking speed,
      decreased grip strength, and decreased muscle mass. Patients with type 2 diabetes are at risk
      of sarcopenia and are those with normal blood sugar. One of the main ways to improve the face
      of sarcopenia is to exercise intensity. By carrying out a gradual training plan instead of
      using different weights, it will lead to muscle hypertrophy and increase in muscle strength
      to achieve muscle gain. In view of the fact that the commercially available sandbags are
      cheap and easy to obtain, the weight is fixed, and the use variability is high, it is
      expected to introduce quantitative weight-bearing progressive exercises in type 2 diabetes
      and have symptoms of muscle loss to improve muscle mass, and to control blood sugar. The
      quality of life can have better benefits.
    

Detailed description: 
      Purpose:This study aim is effectiveness of 12 weeks quantitative weight-bearing progressive
      exercise training in patients with type 2 diabetes mellitus(T2DM) with pre-sarcopenia
      promotion muscle strength and blood sugar control.

      Hypothesis:After 12 weeks of quantitative sandbag training , the experimental group can have
      a significant increase in the muscle mass of the upper and lower limbs、grip strength、5-time
      chair stand test、Lipid profile、glycemic control(HbA1c) and quality of life.

      Methods:This study will be a randomized controlled trial. Forty adult diagnosis with T2DM
      with pre-sarcopenia patient randomly assigned to experimental group and control group.
      Experimental group wearing 0.5 kg quantitative sandbag 12~15 Repetitions/set X 5 set X 3day.
      Weight adjustment: After the first month of intervention, if the experimental can perform for
      more than 20 repetitions/set , we will asked to increase the weight of the sandbag to 1 kg
      until the end of the experiment Conditions:The effectiveness of 12 weeks quantitative
      weight-bearing can improvement of Glycemic control and limb muscle strength.
    

Intervention name(s): Quantitative weight -bearing and report exercise sign data every weekly
Intervention type(s): Behavioral
Intervention description(s): keep their normal live style
Other intervention name(s): Self-manage
Allocation: Randomized
Intervention model: Parallel Assignment
Intervention model description: Forty adult diagnosis with T2DM with pre-sarcopenia patient randomly assigned to experimental group and control group. Experimental group wearing 0.5 kg quantitative sandbag 12~15 Repetitions/set X 5 set X 3day.control group keep normal lives
Masking: Single (Participant)
Primary purpose: Other
Keywords: Resistance training；Muscle strength；Glycemic control