Effect of a Combined Exercise Program on Neuropathic Pain and Perceived Quality of Life in Type 2 Diabetes
Condition: Diabetes Mellitus, Type 2; Neuropathic Pain; Neuropathy, Diabetic
MeSH terms: Neuralgia; Diabetic Neuropathies; Diabetes Mellitus; Diabetes Mellitus, Type 2
Study type: Interventional

Summary: 
      Therapeutic exercise is one of the therapies used as a treatment for diabetic neuropathy,
      which is a complication of diabetes. In order to reduce pain and improve the perception of
      quality of life, a combined therapeutic exercise program will be implemented as an adjuvant
      and non-pharmacological treatment for diabetic neuropathy.
    

Detailed description: 
      This is a prospective, longitudinal, quasi-experimental study of repeated measures
      (pretest-posttest), has been approved by the research and ethics committee of the Faculty of
      Medicine of the Autonomous University of Yucatan, issuing a report on October 26, 2022. An
      identification form will be filled out that will include socio-demographic and clinical data:
      presence of type II diabetes, presence of neuropathy, sex, age, marital status, schooling,
      occupation, BMI, time of diagnosis, HbA1C, insulin use, medical treatment and a neurological
      examination of the extremities. The DN4 questionnaire will be used to evaluate neuropathic
      pain and its characteristics, the VAS will be used to evaluate the degree of intensity or
      severity of pain, and the SF-36 questionnaire will be used to evaluate perception before and
      after the combined exercise program. During the intervention stage, a therapeutic exercise
      program will be applied that will include two modalities: aerobic and resistance exercise in
      the facilities of the Unidad Universitaria de Inserción social de San José Tecoh. The
      duration will be 8 weeks with a frequency of 3 sessions per week, with a duration per session
      of 60 minutes each, to achieve the minimum total time suggested by the guidelines of 150
      minutes per week. These exercises will be prescribed in three phases to increase times,
      series, repetitions and resistances in a progressive manner according to the Borg scale. For
      the analysis of the variables, the parametric Student's t-test for related samples or the
      nonparametric Wilcoxon test with significance at 95% reliability will be used. The
      implementation of the study can demonstrate significant improvements in the symptomatology of
      diabetic neuropathy, directly impacting on the perception of the quality of life of patients
      with type II diabetes.
    

Intervention name(s): Combined Exercise
Intervention type(s): Other
Intervention description(s): Therapeutic exercise program will be applied that will include two modalities: aerobic and resistance exercise. The duration will be 8 weeks with a frequency of 3 sessions per week, with a duration per session of 60 minutes.
Intervention model: Single Group Assignment
Intervention model description: A prospective, longitudinal, quasi-experimental study of repeated measures (pretest-posttest)
Masking: None (Open Label)
Primary purpose: Treatment
Keywords: Diabetes Mellitus type 2; Neuropathic pain; combined exercise