Patients receiving Truvada or any other antiretroviral therapy may continue to develop opportunistic infections and other complications of HIV infection , and therefore should remain under close clinical observation by physicians experienced in the treatment of patients with HIV associated diseases .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The development of opportunistic infections or other complications related to the course of the HIV infection is still possible with Truvada or any other antiretroviral treatment . Appropriate clinical monitoring by a physician experienced in the treatment of HIV infection and associated diseases therefore remains necessary .


Patients receiving emtricitabine or any other antiretroviral therapy may continue to develop opportunistic infections and other complications of HIV infection , and therefore should remain under close clinical observation by physicians experienced in the treatment of patients with HIV associated diseases .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The development of opportunistic infections or other complications related to the course of HIV infection is still possible with emtricitabine . Appropriate clinical monitoring by a physician experienced in the treatment of HIV infection therefore remains necessary .


Patients should be advised that Agenerase , or any other current antiretroviral therapy does not cure HIV and that they may still develop opportunistic infections and other complications of HIV infection .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Patients should be informed that Agenerase , like other current antitretroviral therapy , does not eliminate HIV . The development of opportunistic infections or other complications related to the course of HIV infection is still possible .


Patients should be monitored closely for signs of these side effects during the first 18 weeks of treatment , and blood tests for liver problems should be carried out regularly throughout treatment .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The first 18 weeks of treatment is a critical period which requires close monitoring of patients . Regular blood tests should be done during treatment to check for any liver problems .


Patients should be regularly reassessed by a doctor , so that the strength of Seretide they are receiving remains optimal and is only changed on medical advice .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The doctor should check regularly that the prescribed dosage of Seretide is suitable for the patient's clinical condition . It will only be changed on medical advice .


Patients should be regularly reassessed by a doctor , so that the strength of Viani they are receiving remains optimal and is only changed on medical advice .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The doctor should check regularly that the prescribed strength of Viani is suitable for the patient's clinical condition . It will only be changed on medical advice .


Patients who develop this hypersensitivity reaction must discontinue Kivexa and must never be rechallenged with Kivexa , or any other medicinal product containing abacavir ( Ziagen or Trizivir ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Patients who develop a hypersensitivity reaction should stop Kivexa . In these patients , treatment with Kivexa , or any other medicine containing abacavir ( Ziagen or Trizivir ) , should never be reintroduced .


Patients with cirrhosis may be at a higher risk for hepatic decompensation following hepatitis exacerbation , and therefore should be monitored closely during therapy .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Patients with cirrhosis may have a higher risk of hepatic decompensation after hepatitis exacerbates . They should therefore be closely monitored during treatment .


Pharmacodynamic analysis demonstrated that this was a temporary effect; recovery of normal B-cells began within 6 months and median counts of B-cells were within normal range within 9 months after treatment .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Pharmacodynamic analysis has shown that this phenomenon is only temporary . Recovery of B cells begins within 6 months with a median again falling within normal limits within 9 months of treatment .


Pharmacodynamic effects Aclasta treatment rapidly reduced the rate of bone turnover from elevated post-menopausal levels with the nadir for resorption markers observed at 7 days , and for formation markers at 12 weeks .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Pharmacodynamic effects Treatment with Aclasta rapidly reduces the rate of bone turnover , starting with high postmenopausal rates . The minimum values are observed after 7 days for the resorption markers , and after 12 weeks for the formation markers .


Phosphodiesterase inhibitors which are dependent on CYP3A4 metabolism , such as tadalafil and sildenafil , are expected to result in an approximately 2-fold and 11-fold increase in AUC respectively , when co-administered with ritonavir containing regimens including Kaletra and may result in an increase in PDE5 inhibitor associated adverse reactions including hypotension , synope , visual changes and prolonged erection .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Phosphodiesterase inhibitors whose metabolism is dependent on the CYP3A4 isoform , such as tadalafil and sildenafil , are likely to cause an approximately 2-fold and 11-fold increase in AUC , respectively , in co-administered with regimens containing ritonavir , including Kaletra . Thus , their co-administration with Kaletra could lead to an increase in adverse events associated with PDE5 inhibitors , including hypotension , syncope , visual disturbances and prolonged erection .


Physicians and patients should remain alert for signs and symptoms of gastrointestinal ulceration and haemorrhage during EXJADE therapy and promptly initiate additional evaluation and treatment if a serious gastrointestinal adverse event is suspected .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Doctors and patients should pay attention to any signs and symptoms of gastrointestinal ulceration and bleeding while taking EXJADE . Patient management should be initiated promptly if a serious gastrointestinal adverse event is suspected .


Pioglitazone on its own has been approved by the EU under the name Actos , can be used with metformin in type 2 diabetes patients who are not satisfactorily controlled on metformin alone .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Pioglitazone alone has been approved by the EU under the name Actos . It can be used with metformin in patients with type 2 diabetes that is insufficiently controlled by metformin alone .


Plavix is taken to prevent blood clots ( thrombi ) forming in hardened blood vessels ( arteries ) , a process known as atherothrombosis , which can lead to atherothrombotic events ( such as stroke , heart attack , or death ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Plavix is used to prevent blood clots ( thrombi ) from forming in blood vessels ( arteries ) that have become rigid . This disease also called atherothrombosis can lead to the occurrence of atherothrombotic events ( such as stroke , heart attack , or death ) .


Powder in a vial ( type I glass ) with a stopper ( fluor-resin laminated butyl rubber ) , a strip ( aluminium ) and a cap ( violet polypropylene flip-off ) , and 1 ml of solvent in a vial ( type I glass ) with a stopper ( fluor-resin laminated chlorobutyl elastomer ) , a strip ( lacquered aluminium ) and a cap ( white polypropylene flip-off ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Powder in a vial ( type I glass ) with a stopper ( laminated rubber butyl fluoro-resin ) , a film and a cap ( polypropylene , flip-off type ) , and a 1 ml vial of solvent .  ( type I glass ) fitted with a stopper ( elastomer laminated in chloro-butyl fluoro resin ) , a film ( lacquered aluminum ) and a flip-off type cap ( white polypropylene ) .


Pre- treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before commencement of treatment .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Prior treatment with anti-inflammatory substances may lead to the appearance or worsening of side effects . It is therefore recommended to observe a period free from such treatments of at least 24 hours before starting the treatment .


Pre-treatment with other anti- inflammatory medicines may result in additional or increased adverse effects and , accordingly a treatment-free period with such substances should be observed for at least 24 hours before the commencement of treatment with Onsior .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Prior treatment with other anti-inflammatory medicines may increase side effects or cause additional side effects . Therefore , a period of at least 24 hours without treatment should be observed before the start of treatment with Onsior .


Prior to initiating therapy with TRISENOX , a 12-lead ECG must be performed and serum electrolytes ( potassium , calcium , and magnesium ) and creatinine must be assessed; preexisting electrolyte abnormalities must be corrected and , if possible , medicinal products that are known to prolong the QT interval must be discontinued .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Before starting treatment with TRISENOX , a 12-lead ECG will be performed , as well as a serum test for electrolytes ( potassium , calcium and magnesium ) and creatinine . Pre-existing electrolyte abnormalities will be corrected and , if possible , treatments known to prolong the QT interval will be discontinued .


Priority in the step-by-step approach was given to taxes , actual social contributions and social benefits other than social transfers in kind , as categories representing reliable indicators of trends in public finances that are already available on time ( first step ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In the step-by-step approach , priority has been given to the categories of taxes , actual social contributions and social benefits excluding social transfers in kind . These categories are reliable indicators that indicate the trend of public finances and are now available on time ( first step ) .


PritorPlus may increase the blood pressure lowering effect of other medicines and you should consult with your doctor if you need to adjust the dose of your other medicine while taking PritorPlus .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

PritorPlus may increase the blood pressure lowering effect of other medicines . You should check with your doctor to see if the dose of these other medicines needs to be adjusted while you are taking PritorPlus .


Provisional duties shall be secured by a guarantee and the release of the products concerned for free circulation in the Community shall be conditional upon the provision of such guarantee .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

A security must be lodged for the amount of the provisional duties . The products in question may not be released for free circulation in the Community until a security has been lodged .


Pursuant to Directive 2002/60/EC , Italy has submitted for approval a plan for the eradication of African swine fever in feral pigs in the region of Sardinia , that also includes measures to prevent spread of disease in domestic pigs .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In accordance with Directive 2002/60 / EC , Italy has submitted for approval a plan for the eradication of African swine fever in the feral pig population in the region of Sardinia . This plan also includes measures to prevent the spread of the disease in domestic pigs .


Race Pharmacokinetic studies show an increase in exposure in Japanese and Chinese subjects compared with Caucasians ( see section 4 . 2 Posology and Method of administration and section 5 . 2 Pharmacokinetic properties )
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Pharmacokinetic studies show an increase in exposure in Japanese and Chinese subjects compared to Caucasians .  ( See sections 4-4 Special warnings and special precautions for use and 5-2 Pharmacokinetic properties ) .


Ranexa is a medicine used in combination with other medicines to treat angina pectoris , which is a chest pain or discomfort that you feel anywhere along the upper part of your body between your neck and upper abdomen , often brought on by exercise or too much activity .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Angina pectoris is pain or discomfort in the chest that can be felt in various places on the upper body between the neck and the upper abdomen . Angina pectoris is usually caused by exercise or being overactive .


Regarding cardiac dysfunction , this was one of the exclusion criteria so the studies give no information on use of the product in animals with such a condition but there is also no data suggesting that the cardiac patients must not be treated with the substance .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Heart failure was one of the exclusion criteria , which is why studies do not provide information on the use of the product in animals with such a disorder . However , none of the data collected suggests an impossibility of treating the cardiac subject with this substance .


Renal insufficiency: the pharmacokinetics of efavirenz have not been studied in patients with renal insufficiency; however , less than 1% of an efavirenz dose is excreted unchanged in the urine , so the impact of renal impairment on efavirenz elimination should be minimal ( see section 4 . 2 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Renal Impairment: The pharmacokinetics of efavirenz have not been studied in patients with renal impairment . However , as less than 1% of the dose of efavirenz is excreted unchanged in the urine , renal impairment is expected to have little influence on the elimination of efavirenz ( see section 4 . 2 ) .


Rifampicin: co-administration in 9 healthy subjects of Tracleer 125 mg twice daily for 7 days and rifampicin , a potent inducer of CYP2C9 and CYP3 A4 , decreased the plasma concentrations of bosentan by 58% , and this decrease could achieve almost 90% in an individual case .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Rifampicin: Concomitant use of Tracleer 125 mg twice daily for 7 days in 9 healthy volunteers and rifampicin , a potent inducer of CYP2C9 and CYP3A4 , resulted in a 58% decrease in plasma bosentan concentration . This decrease reached nearly 90% in one of the subjects .


SPF eggs are not speficically definied as such in Community legislation therefore a specific definition has to be laid down .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Eggs free from specific pathogenic organisms are not explicitly defined as such in Community legislation . A specific definition should therefore be established .


Sales of total REWS units made by the Community industry on the Community market fell over the period 1994 to 1996 , but then increased in line with the Euro-effect as explained at recital 34 .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The volume of unit sales of all types of REWS of the Community industry on the Community market decreased between 1994 and 1996 . Subsequently , it increased for the "euro effect" as explained in recital 34 .


Salmeterol produces a longer duration of bronchodilation , lasting for at least 12 hours , than recommended doses of conventional short-acting beta-2-agonists .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Salmeterol produces bronchodilation which persists for about 12 hours . This duration is greater than that generally observed with short-acting beta-2 mimetics administered at the usual dosages .


Saquinavir does not induce chromosomal damage in vivo in the mouse micronucleus assay or in vitro in human peripheral blood lymphocytes and does not induce primary DNA damage in vitro in the unscheduled DNA synthesis test .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Saquinavir does not induce chromosomal damage in vivo when tested for the micronucleus in mice or in vitro in human peripheral blood lymphocytes . It does not induce primary DNA damage in vitro during the unscheduled DNA synthesis test .


Serum antibodies have been shown to persist in chickens for at least 7 months and studies performed with other vaccine strains show that serum antibodies would be expected to persist in chickens for at least 12 months after administration of two doses of vaccine .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Serum antibodies have been shown to persist for at least 7 months in hens . Studies with other vaccine strains have shown that serum antibodies can persist for at least 12 months after receiving two doses of the vaccine .


Sevoflurane causes dose-dependant respiratory depression , therefore respiration should be closely monitored during sevoflurane anaesthesia and the inspired concentration of sevoflurane adjusted accordingly .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Sevoflurane causes dose-dependent respiratory depression . Respiration should therefore be carefully monitored during sevoflurane anesthesia , and the inspired concentration of sevoflurane will be adjusted accordingly .


Should you experience a significant increase in your usage of BeneFIX in order to control a bleed , please contact your doctor immediately; your blood should be checked for inhibitors to factor IX activity .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

If you need to significantly increase the doses of BeneFIX to control a bleeding episode , contact your doctor immediately . A blood test will be performed to detect the presence of factor IX inhibitors .


Since PROCOMVAX has not been studied in persons who have malignancies or are otherwise immunocompromised , the extent of the immune response in such persons is unknown .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

PROCOMVAX has not been studied in people with malignant tumors or immune deficiency of another origin . The level of the immune response in these people is not known .


Since it would be expensive and disruptive to have a toll booth at each end of the tunnel for each Member State to collect their share of the toll , tolls are collected as a whole at the entrance of the tunnel .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The installation of a toll system at both ends of the tunnel , allowing each of the Member States concerned to collect its share of the toll , would be expensive and would have disruptive effects . Therefore , tolls are collected globally at the entrance to the tunnel .


Since montelukast is metabolised by CYP 3A4 , caution should be exercised , particularly in children , when montelukast is coadministered with inducers of CYP 3A4 , such as phenytoin , phenobarbital and rifampicin .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Montelukast is metabolized by CYP 3A4 . Therefore , caution is required , especially in children , when co-administering montelukast with CYP 3A4 inducing drugs such as phenytoin , phenobarbital and rifampin .


Since there have been no cases of overdose reported to date , neither signs nor symptoms of overdose have been identified .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

To date , no case of overdose has been reported . Accordingly , no signs or symptoms of overdose can be described .


Since there is no change in pharmacokinetics in patients with impaired renal function , and since there are no signs that doxazosin aggravates existing renal impairment , the usual dose can be used in these patients ( see section 4 . 4 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

No alteration of pharmacokinetic characteristics is noted in patients with renal impairment and there is no evidence that doxazosin may worsen existing renal impairment . The usual dose can therefore be used in these patients ( see section 4 . 4 ) .


Since vildagliptin is not a cytochrome P ( CYP ) 450 enzyme substrate and does not inhibit or induce CYP 450 enzymes , it is not likely to interact with active substances that are substrates , inhibitors or inducers of these enzymes .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Vildagliptin is not a substrate , inhibitor or inducer of cytochrome P 450 ( CYP450 ) enzymes . therefore , it is unlikely to interact with active substances which are substrates , inhibitors or inducers of these enzymes .


Skin patch testing was used as a research tool for the PREDICT-1 study but has no utility in the clinical management of patients and therefore should not be used in the clinical setting .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

A patch test was used as a research tool in the PREDICT-1 study but has no utility in the clinical management of patients . Therefore , it should not be used in clinical practice .


Some Marketing Authorisation Holders ( Annex IV ) appealed against the opinion and the grounds for appeal were received on 15 April 1996 .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

A few marketing authorization holders ( Annex IV ) appealed against this opinion . The grounds for their appeal were received on April 15 , 1996 .


SonoVue is a transpulmonary echocardiographic contrast agent for use in patients with suspected or established cardiovascular disease to provide opacification of cardiac chambers and enhance left ventricular endocardial border delineation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

SonoVue is an echocardiographic contrast medium , crossing the pulmonary capillary bed , used in patients with known or suspected cardiovascular disease . It allows the opacification of the heart chambers and improves the definition of the endocardial relief of the left ventricle .


Special precautions for use in animals Halogenated volatile anaesthetics can react with dry carbon dioxide ( CO2 ) absorbents to produce carbon monoxide ( CO ) that may result in elevated levels of carboxyhaemoglobin in some dogs .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Special precautions for use in animals Volatile halogenated anesthetics may react with dry carbon dioxide ( CO2 ) absorbers . This reaction leads to the production of carbon monoxide ( CO ) , which can result in increased levels of carboxyhemoglobin in some dogs .


Specifically , consumers should enjoy a minimum level of legal certainty in respect of their contractual relations with their direct telephone service provider , such that the contractual terms , conditions , quality of service , condition for termination of the contract and the service , compensation measures and dispute resolution are specified in their contracts .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Consumers in particular should enjoy a minimum level of legal certainty with regard to their contractual relationships with their direct telephone service provider . To this end , the contract terms and conditions , quality of service , terms and conditions for termination of the contract and service , compensation measures and dispute settlement should be specified in their contracts .


Stiripentol is quickly absorbed , with a time to peak plasma concentration of about 1 . 5 hours .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Stiripentol is rapidly absorbed . It reaches its peak plasma concentration after about 1 . 5 hours .


Subjects with renal impairment Cmax and AUC of rivastigmine were more than twice as high in subjects with moderate renal impairment compared with healthy subjects; however there were no changes in Cmax and AUC of rivastigmine in subjects with severe renal impairment .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Subjects with renal impairment In subjects with moderate renal impairment , the peak plasma concentration and AUC are more than doubled compared to subjects with normal renal function . In contrast , in severe renal failure , no change in Cmax or AUC was found .


Such confirmation is necessary in order to permit the detailed examination of the dossier as well as to allow Member States the possibility of granting provisional authorisation for plant protection products containing this active substance in accordance with Article 8 ( 1 ) of the Directive .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

This determination is necessary to enable a detailed examination of the documents . It is also intended to give the Member States the opportunity to grant provisional authorization for plant protection products with the relevant active substance in accordance with Article 8 ( 1 ) of the Directive .


Survival and tumour progression have been examined in five large controlled studies involving a total of 2 833 patients , of which four were double-blind placebo-controlled studies and one was an open- label study .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Survival and tumor progression were evaluated in five large controlled studies involving a total of 2833 patients . Of these studies four were double-blind , placebo-controlled and one was open-label .


Table 2 lists the adverse reactions recorded in the pooled 104-week NV-02B-007 GLOBE and NV- 02B-015 studies by system organ class and by frequency using the following convention: very common ( 1/ 10 ) ; common ( 1/ 100 to < 1/ 10 ) ; uncommon ( 1/ 1 , 000 to < 1/ 100 ) ; rare ( 1/ 10 , 000 to < 1/ 1 , 000 ) ; very rare ( < 1/ 10 , 000 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Table 2 shows the adverse reactions recorded in the 104 week studies NV-02B-007 GLOBE and NV-02B-015 . These side effects are listed by system organ class and frequency using the following convention: very common ( 1/10 ) ; common ( 1/100 , <1/10 ) ; uncommon ( 1/1000 , <1/100 ) ; rare ( 1 / 10 , 000 , <1 / 1 , 000 ) ; very rare ( <1 / 10 , 000 ) .


Taking into account the specific needs , capabilities and constraints of the OCT , financial assistance should be granted to the OCT as budgetary support , provided the OCT management of public expenditure presents sufficient transparency , accountability and effectiveness .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Taking into account the specific needs , capacities and constraints of the OCTs , financial assistance should be granted to them . It may take the form of budgetary support , provided that the management of public expenditure by the OCTs presents a sufficient degree of transparency , reliability and efficiency .


Tarceva has not been studied for its possible effects on the ability to drive and use machines but it is very unlikely that your treatment will affect this ability .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The effects of Tarceva on the ability to drive and use machines have not been studied . However , it is very unlikely that your treatment will affect them .


Taxotere/ Docetaxel Winthrop was also expected to be used to treat breast cancer that can be treated with surgery when the cancer has been shown to be expressing large amounts of HER2: this is a type of cancer that produces ( expresses ) a specific protein called HER2 in large quantities on the surface of the tumour cells .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Taxotere / Docetaxel Winthrop was also expected to be used to treat breast cancer which cannot be treated with surgery when it was found to "express" large amounts of HER2 . It is a type of cancer that produces ( expresses ) a specific protein called HER2 in large quantities on the surface of cancer cells .


Tell your doctor if you have ever had any allergic type reactions due to other medicines as Fasturtec can cause allergic-type reactions , including severe cases .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Tell your doctor if you have ever had allergic-type reactions to any other medicine . Fasturtec can cause reactions of this type , sometimes serious .


The 1997 budget , as last amended by Management Board , totals ECU 28 . 2 million , made up of a subsidy of ECU 14 million from the EU general budget , expected fee revenue of ECU 14 million and ECU 200 000 from bank interest .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The 1997 budget , as last amended by the Management Board , amounts to a total of ECU 28 . 2 million . It is made up of a contribution of 14 million ECU from the general budget of the EU , an amount of 14 million ECU corresponding to the planned fees and a sum of 200 , 000 corresponding to bank interest .


The 24-hour concentration following a high fat meal was increased by approximately 33% due to delayed absorption; the median Tmax increased from 2 . 0 to 5 . 0 hours .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Following a high fat meal , concentration at 24 hours was increased by about 33% due to delayed absorption . The median Tmax increased from 2 . 0 to 5 . 0 hours .


The 5 -glucuronide of zidovudine is the major metabolite in both plasma and urine , accounting for approximately 50 to 80% of the administered dose eliminated by renal excretion .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The 5 -glucuronide compound of zidovudine is the main metabolite found in plasma and urine . It represents approximately 50 to 80% of the dose administered and excreted via the kidneys .


The Administrative Council shall hold an ordinary meeting once a year; in addition , it shall meet on the initiative of its Chairman or at the request of the Commission or of one-third of the Member States .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The board of directors meets in ordinary session once a year . It also meets on the initiative of the President or at the request of the Commission or one third of the Member States .


The Applicant/ MAH subsequently proposed to follow the same proposal for other diarrhoea indications , taking into account data supporting oral 500 mg bid daily dose and considering bioavailability purposes , the corresponding IV dosage should be 400 mg bid .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Subsequently , the Applicant / MAH proposed to follow the same proposal as for the other indications of diarrhea , taking into account the data in favor of an oral daily dose of 500 mg twice daily . To achieve bioavailability goals , the corresponding intravenous dosage should be 400 mg twice daily .


The CHMP also assessed the optimal , recommended dose range for bipolar mania and considered , based on the submitted efficacy analysis of risperidone patients , grouped according to their mode daily dose during the study , that efficacy was demonstrated over the recommended dose range 1 to 6 mg/ day , and that some patients can effectively be treated at doses in the lower end of this dose range .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The CHMP also assessed the range of optimal and recommended doses for bipolar mania . On the basis of the presented analysis of the efficacy of risperidone in patients grouped according to their daily dose during the study , it considered that the efficacy of the treatment was demonstrated in the recommended dose range of 1 to 6 . mg / day and that some patients can be treated effectively at doses within the lower end of this range .


The CHMP noted the pivotal study JHQJ was powered to detect differences in TtDP in overall survival and that the pivotal study for the ovarian cancer had a specific population consisting of platinum sensitive patients with a very poor prognosis and the CHMP was of the opinion that the proposed wording was in accordance with the submitted study for the marketing authorisation in this indication .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The CHMP noted that the JHQJ core study was carried out to detect differences in the time to disease progression on overall survival and that the core ovarian cancer study was performed in a specific population consisting of platinum-sensitive patients with a very poor prognosis . The CHMP was of the opinion that the proposed formulation was in agreement with the study submitted for the marketing authorization for this indication .


The CVMP concluded that the benefits of Flexicam exceed the risks for the alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders , reduction of post-operative pain and inflammation following orthopaedic and soft tissue surgery in dogs and reduction of post-operative pain after ovariohysterectomy and minor soft tissue surgery in cats and recommended that Flexicam be given a marketing authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The CVMP therefore decided that Flexicam's benefits are greater than its risks for the reduction of inflammation and pain in acute and chronic musculoskeletal disorders , for the reduction of postoperative pain and inflammation following orthopedic or soft tissue surgery in dogs , as well as for postoperative pain reduction after ovariohysterectomy and minor soft tissue surgery in cats . It recommended that marketing authorization be granted for Flexicam .


The Commission cannot accept the argument concerning the schemes limited effects on competition , because the fact that the measure remains in force for only one year does not rule out the possibility that the amounts involved may be large enough to have significant effects on certain markets .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Commission cannot accept the argument that the scheme has limited effects on competition . Indeed , the fact that the aid scheme is only in force for a period of one year does not exclude the amounts concerned from being large enough to have a significant impact on certain markets .


The Commission concludes that the complementary set of proxies can be used for a first qualification of the bids to assess whether the bids are for high-function software for large and complex enterprises .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Commission concludes that the complementary set of indicators can be used for an initial classification of tenders . This can be used to assess whether the tenders concern high-function software for large , complex companies .


The Commission has accordingly sought to ensure an overall contraction in the volume of business in line with its practice in the past but , above all , also an effective reduction in the banks presence on the markets , having regard to the effects of the measures proposed on the individual lines of business .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In the light of the situation , the Commission , following its usual practice , has set itself the aim of ensuring an adequate reduction of the total volume . The Commission has mainly set itself the objective of ensuring an effective reduction of the bank's presence on the markets , taking into account the effects of the measures it intended to take .


The Commission has negotiated on behalf of the Community an agreement to extend for one year the existing Agreement and protocols on trade in textile products with the Republic of Belarus , with quantitative limits adjusted to take into account annual growth rates and Belarussian demand for some categories .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Commission has negotiated on behalf of the Community an Agreement extending by one year the Agreement and the Protocols currently governing trade in textile products with the Republic of Belarus . The quantitative limits have been adjusted to take into account the annual growth rates and the demands made by Belarus for certain categories .


The Commission here believes that internalisation of costs is a priority objective that can be achieved in various ways , including by way of instruments based on market laws or those based on a regulatory approach , these being the most effective tools for achieving the objectives described above .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In this context , the Commission is of the opinion that the internalisation of costs is a priority objective to be achieved . This can be achieved by various means such as policy instruments based on the law of the market , or those based on a regulatory approach , which constitute the most effective tools to achieve the objectives described above .


The Commission notes that such a distortion seems to be inherent in the very nature of the project in question but has accepted distortions of this kind in other cases involving transport infrastructures because , in its view , the benefits of such projects outweighed those distortions .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Commission notes that this distortion appears to be inherent in the nature of the project in question . However , in other transport infrastructure cases , it admitted similar distortions considering that the benefits of such projects outweighed the distortions .


The Commission received comments from third parties , which were forwarded to the French authorities by letter dated 11 February 2003 and to which the French authorities replied by letter dated 9 April 2003 .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Commission received comments from third parties which were forwarded to the French authorities by letter of 11 February 2003 . For their part , the French authorities responded to these comments by letter of 9 April 2003 .


The Commission shall draw up a report on the operation of this Regulation before the end of the fourth year following its entry into force and shall , on that basis , assess whether any adaptation of the Regulation is desirable .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Before the end of the fourth year after the entry into force of this Regulation , the Commission shall draw up a report on its operation . On this basis , it assesses whether the regulation needs to be amended .


The Commission shall submit , by the end of 1991 , a report on the operation of the system , including a re-examination of the correction of budgetary imbalances granted to the United Kingdom , established by this Decision .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Before the end of 1991 , the Commission shall report on the operation of the scheme introduced by this Decision . This report also includes a re-examination of the correction for budgetary imbalances granted to the United Kingdom .


The Committee for Medicinal Products for Human Use ( CHMP ) decided that the benefits of Soliris are greater than its risks for the treatment of patients with PNH , but noted that evidence of the benefit of Soliris is limited to patients who have had blood transfusions in the past .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Medicinal Products for Human Use ( CHMP ) decided that the benefit / risk ratio of Soliris was favorable for the treatment of patients with PNH . The Committee noted , however , that the benefits of Soliris are limited to patients who have had blood transfusions in the past .


The Committee for Medicinal Products for Veterinary Use ( CVMP ) concluded that the benefits of Dicural are greater than the risks for the treatment and recommended that Dicural be given a marketing authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Medicinal Products for Veterinary Use ( CVMP ) decided that Dicural's benefits are greater than its risks in this treatment . It therefore recommended the granting of a marketing authorization for Dicural .


The Committee for Medicinal Products for Veterinary Use ( CVMP ) concluded that the benefits of Easotic exceed the risks for the treatment of acute otitis externa , and acute exacerbation of recurrent otitis externa associated with bacteria susceptible to gentamicin and fungi susceptible to miconazole in particular Malassezia pachydermatis , and recommended that Easotic be given a marketing authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Medicinal Products for Veterinary Use ( CVMP ) decided that Easotic's benefits are greater than its risks in the treatment of acute otitis externa and the acute exacerbation of recurrent otitis externa associated with bacteria susceptible to gentamicin and the fungus sensitive to miconazole , in particular Malassezia pachydermatis . It recommended the granting of the marketing authorization for Easotic .


The Committee for Medicinal Products for Veterinary Use ( CVMP ) concluded that the benefits of Porcilis PCV exceed the risks for the active immunisation of pigs , over the age of three days , against PCV2 , and recommended that Porcilis PCV be given a marketing authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Veterinary Medicinal Products ( CVMP ) decided that Porcilis PCV's benefits are greater than its risks in the active immunization of pigs , from 3 days of age , against PCV2 . It therefore recommended the granting of a marketing authorization for Porcilis PCV .


The Committee for Medicinal Products for Veterinary Use ( CVMP ) concluded that the benefits of Posatex exceed its risks for the treatment of acute otitis externa and acute exacerbations of recurrent otitis externa in dogs and recommended that Posatex be given a marketing authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Medicinal Products for Veterinary Use ( CVMP ) decided that Posatex's benefits are greater than its risks for the treatment of acute otitis externa and acute exacerbations of recurrent otitis externa in dogs . It recommended the granting of the marketing authorization for Posatex .


The Committee for Medicinal Products for Veterinary Use ( CVMP ) concluded that the benefits of Profender exceed the risks for cats or dogs suffering from , or at risk from , mixed parasitic infections , and recommended that Profender be given a marketing authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Medicinal Products for Veterinary Use ( CVMP ) decided that Profender's benefits are greater than its risks for dogs and cats with or at risk of mixed parasitic infections . It recommended the granting of a marketing authorization for Profender .


The Committee for Medicinal Products for Veterinary Use ( CVMP ) concluded that the benefits of Pruban exceeded the risks for the treatment of acute localised moist dermatitis in dogs , and recommended that Pruban be granted a market authorisation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Committee for Medicinal Products for Veterinary Use ( CVMP ) decided that Pruban's benefits are greater than its risks for the treatment of acute localized exudative dermatitis in dogs . It recommended the granting of a marketing authorization for Pruban .


The Community has concluded a further ECSC steel agreement with the Russian Federation concerning trade in certain steel products covered by the European Coal and Steel Community Treaty which take account of developments in the relationship between the Parties ( 2 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Community has concluded another ECSC Steel Agreement with the Russian Federation on trade in certain steel products covered by the Treaty establishing the European Coal and Steel Community . This agreement takes into account the development of relations between the parties ( 2 ) .


The Community producers market share increased from 26 , 5 % in 2000 to 28 , 1 % in 2001 and remained at about this level in 2002 , but then fell by 1 , 9 percentage points ( or 6 , 7 % ) to 26 , 1 % in 2003 , its lowest level in the period considered .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The market share of Community producers rose from 26 . 5% in 2000 to 28 . 1% in 2001 , reaching approximately this level in 2002 . It then dropped to 26 . 1% in 2003 , losing 1 . 9 percentage points ( or 6 . 7% ) and recording the lowest level in the period under review .


The German authorities have informed the Commission on the re-occurrence during October 2005 of the disease in feral pigs in certain areas of North Rhine-Westfalia and have amended the plans for the eradication of classical swine fever and the emergency vaccination of feral pigs against classical swine fever accordingly and notified it to the Commission .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The German authorities have informed the Commission that in October 2005 the disease reappeared in the wild boar population in certain areas of North Rhine-Westphalia . As a result , they changed their plans to eradicate classic swine fever in the wild boar population and to provide emergency vaccination for wild boars and brought these changes to the attention of the Commission .


The MAH agreed that platinum-based combination therapies are the standard of care but defended the use of gemcitabine monotherapy in the treatment of elderly patients and patients with a Performance Status of 2 , as these groups are at higher risk for chemotherapy-related morbidities or in cases where platinum-based combinations cannot be tolerated .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Marketing Authorization Holder confirmed that platinum-based combination therapies are standard of care , but supported the use of gemcitabine monotherapy in the treatment of elderly patients and patients with performance status 2 . Indeed these groups are exposed to higher risks of morbidity because of chemotherapy or when platinum-based combinations are not tolerated .


The MAH agreed that the indication is redundant because the first line treatment of pancreatic treatment with gemcitabine is standard of care and agreed to remove it .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The marketing authorization holder concedes that the indication is redundant: in fact , the first-line treatment for pancreatic treatment with gemcitabine is standard treatment . He therefore agreed to delete it .


The Member States shall authorise the importation from Canada of fresh meat of domestic swine conforming to the certification conditions laid down in the model certificate set out in Annex II , and accompanied by such a certificate duly completed and issued before departure of the consignment from Canada .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Member States shall authorize the import , in accordance with the certification conditions set out in the model certificate set out in Annex II , the import from Canada of fresh meat of domestic animals of the porcine species . A copy duly completed and issued before the consignment leaves Canada must accompany the pork meats so imported .


The Ombudsman shall be assisted by a secretariat , the principal officer of which he shall appoint .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The ombudsman is assisted by a secretariat . He appoints the head thereof .


The Safety of Residues Working Party will continue to progress MRLs for old substances and will complete the guidelines on standardisation of withdrawal periods in milk in early 1997 , as well as revising those requirements for MRLs for substances for use in minor species and redefining the target tissues for which MRLs should be established generally .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The Residue Safety Working Group will continue to establish MRLs for existing products and will complete the drafting of guidelines for standardization of withdrawal periods in milk in early 1997 . It will also review the requirements for MRLs for products used in minor species and re-define target tissues for which MRLs should generally be established .


The absorption of nelfinavir may be reduced in conditions where gastric pH is increased , therefore concomitant use of VIRACEPT with Proton Pump Inhibitors is not recommended ( see section 4 . 4 ) , except for omeprazole which is contra-indicated ( see section 4 . 3 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Absorption of nelfinavir may be decreased in situations where gastric pH is increased . Therefore , the concomitant use of VIRACEPT and proton pump inhibitors is not recommended ( see section 4 . 4 ) , except for omeprazole where it is contraindicated ( see section 4 . 3 ) .


The absorption profile of Effentora is largely the result of an initial rapid absorption from the buccal mucosa , with peak plasma concentrations following venous sampling generally attained within an hour after oromucosal administration .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The absorption profile of Effentora results largely from rapid initial absorption from the oral mucosa . Blood samples show that peak plasma concentrations are obtained within one hour of oral transmucosal administration .


The active moiety in zinc acetate dihydrate is zinc cation , which blocks the intestinal absorption of copper from the diet and the reabsorption of endogenously secreted copper .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Zinc in the form of a cation constitutes the active moiety of zinc acetate dihydrate . It blocks the intestinal absorption of copper from food and the reabsorption of endogenous secreted copper .


The active substance in Cerenia , maropitant , is broken down via the liver and it is , therefore , recommended to use it with caution in dogs with liver disease .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The active substance in Cerenia , maropitant , is metabolized by the liver . It is therefore recommended to be used with caution in dogs with liver disease .


The advisory procedure should be followed in any case in which it is considered to be the most appropriate; the advisory procedure will continue to be used in those cases where it currently applies;
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The advisory procedure should be used wherever it is considered the most appropriate . The advisory process will continue to be used in those cases where it is already in use .


The analgesic effects of fentanyl are related to the blood level of the active substance; in opioid-naive patients , minimum effective analgesic serum concentrations of fentanyl range from 0 . 3-1 . 2 ng/ ml , while blood levels of 10-20 ng/ ml produce surgical anaesthesia and profound respiratory depression .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The analgesic effects of fentanyl are related to the plasma concentrations of the active substance . In subjects who have never received opioid therapy , the minimum blood levels of fentanyl producing an effective analgesic effect are between 0 . 3 and 1 . 2 ng / ml .


The application referred to in paragraph 1 shall specify the activity for which the building will be used and give any other information that will enable the customs authorities to evaluate the grounds for granting the authorization .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The application referred to in paragraph 1 must state the activity for which the building will be used . This application shall also contain all the information enabling the customs authorities to assess whether they can issue the authorization .


The appropriations in their entirety shall be earmarked for specific purposes by title and chapter; the chapters shall be further subdivided into articles and items .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

All funds are factually classified according to titles and chapters . The chapters are divided into articles and items .


The available data indicate that the rate of clinically relevant infection is unchanged when such therapies are used in patients previously treated with MabThera , however patients should be closely observed for signs of infection if biologic agents and/ or DMARDs are used following MabThera therapy .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The available data indicate that the rate of clinically relevant infection is unchanged when such treatments are used in patients previously treated with MabThera . However , patients should be closely monitored for signs of infection if they are receiving biological agents and / or other DMARDs after their treatment with MabThera .


The capsules work only in your digestive system to stop about a quarter of the fat in your meals from being absorbed .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The capsules only work on your digestive system . They prevent about a quarter of the fat in your meals from being absorbed .


The colorforming reaction is conferred on the paper by the basic chemical molecule , in a reaction where , the application of heat or pressure opens up the ring in the basic molecule .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The dye-forming reaction of the basic molecule proceeds on paper . The ring structure is opened under the influence of heat or pressure .


The colostrum is collected and filtered and the lactoserum ( the whey , the liquid part of milk ) is concentrated to make Locatim .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

This colostrum was then harvested and filtered . The whey ( whey , the liquid part of the milk ) was then concentrated to give the Locatim product .


The company that makes Aclasta will provide educational packs for doctors who prescribe Aclasta for osteoporosis , reminding them how the medicine should be used , and similar packs for patients , which explain the medicine s side effects and when they should contact their doctor .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The company that makes Aclasta will provide information kits reminding doctors of how this medicine is to be used to doctors who prescribe Aclasta as an anti-osteoporosis treatment . Similar kits will be provided to patients to clarify the side effects of the drug and when they should contact their doctor .


The competent authority responsible for the checks in slaughterhouses shall provide to the Commission at the latest on 25 of each month a report in accordance with the format in Annex V which shall cover the checks carried out during the preceding month and the measures taken to remedy detected animal health and welfare shortcomings .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The competent authority responsible for controls in slaughterhouses shall submit a report to the Commission in the format set out in Annex V by the twenty-fifth of each month . This report shall indicate the controls carried out during the previous month and the measures taken to remedy identified deficiencies in animal health and welfare .


The complaint contained evidence of dumping of the said product and of material injury resulting therefrom , which was considered sufficient to justify the initiation of the proceedings .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The complaint contained evidence of dumping of the product in question and of material injury caused thereby . This evidence was considered sufficient to justify the initiation of the proceedings .


The condition as set out in paragraph 1 ( b ) of the Annex provided for Bombardier to enter into a Joint Development Agreement with ETR for cooperation between these two companies until 2006 in relation to the tram "CityRunner Type Linz" , for which ETR supplies the electrical traction , thereby allowing ETR to continue to be active in the market for trams .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The condition of paragraph 1 ( b ) of the Annex was that Bombardier had to conclude a joint development agreement with ETR . The subject matter was a collaboration between the two companies until 2006 in the development of the Cityrunner Linz trams , for which ETR supplies the electrical traction so that ETR can remain active on the tram market .


The confidentiality of communications is guaranteed by Article 5 Directive 97/66/EC; in accordance with that Directive , Member States must prohibit any kind of interception or surveillance of such communications by others than the senders and receivers , except when legally authorised .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The secrecy of communications is guaranteed by Article 5 of Directive 97/66 / EC . In accordance with this Directive , Member States must prohibit any kind of unlawful interception or the surveillance of such communications by others than senders and receivers , except where such activities are legally permitted .


The contribution of the new Member shall be calculated on the basis of the share allotted to that Member and of the unexpired portion of the year in question at the time of the accession of the new Member , but the assessments made upon the other Members for that calendar year shall not be altered .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The contribution of the new member is calculated on the basis of the share allocated to that member and the part of the current year remaining at the time the new member joins . However , the fees set for the other members for the current calendar year will not be changed .


The criteria relating to inland ports should be supplemented by criteria concerning either the nature of their equipment or the volume of traffic and those ports should be shown , by way of indication , on maps .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The criteria for inland ports are to be supplemented by criteria relating either to the type of port facilities or the volume of traffic . These ports should be shown on information maps .


The database of authorised medicinal products in the EU will make authoritative , up-to-date information on all these products available to regulators , health professionals and the general public; while the current version of the application is already available to EU regulators , public access will be provided by September 2006 .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The EU Authorized Medicines Database will make up-to-date and authoritative information on all products available to regulators , healthcare professionals and the general public . While the current version of this application is already available to regulators in the EU , it will be available to the general public by September 2006 .


The diphtheria and tetanus toxoids are prepared from the toxins of cultures of Corynebacterium diphtheriae and Clostridium tetani by formaldehyde detoxification followed by purification .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Diphtheria and tetanus toxoids are prepared from toxins extracted from cultures of Corynebacterium diphtheriae and Clostridium tetani . They are detoxified with formaldehyde and then purified .


The dose can be increased to the 8 mg/ 4 mg tablets after eight weeks if needed , but this should be done with caution , due to the risk of fluid retention .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

It can be increased to 8 mg / 4 mg after eight weeks , if necessary . However , this passage must be operated with caution due to the risk of water retention .


The duration of treatment depends on the patient s condition and response to treatment , and ranges from 24 weeks to a year .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The duration of treatment depends on the patient's condition and response to treatment . It can range from 24 weeks to a year .


The duration of treatment should be kept as short as possible and should not be continued after the symptoms have disappeared .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The duration of treatment should be as short as possible . Treatment should not be continued after symptoms have resolved .


The duties of the President shall be to open , suspend and close sittings; to rule on the admissibility of amendments , on questions to the Council and Commission , and on the conformity of reports with these Rules; to ensure observance of these Rules , maintain order , call upon speakers , close debates , put matters to the vote and announce the results of votes; and to refer to committees any communications that concern them .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

It rules on the admissibility of amendments , on questions addressed to the Council and the Commission and on the conformity of the reports with the regulation . He ensures that the rules are observed , maintains order , gives the floor to speak , declares the discussions closed , puts questions to the vote and announces the results of the votes .


The effects of ORENCIA in pregnancy are not known , so do not use ORENCIA if you are pregnant unless your doctor specifically recommends it .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The effects of ORENCIA on pregnancy are not known . Therefore , do not use ORENCIA if you are pregnant , unless your doctor specifically recommends it .


The effects of arsenic , cadmium , mercury , nickel and polycyclic aromatic hydrocarbons on human health , including via the food chain , and the environment as a whole , occur through concentrations in ambient air and via deposition; the accumulation of these substances in soils and the protection of ground water should be taken into account .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The effects of arsenic , cadmium , mercury , nickel and polycyclic aromatic hydrocarbons on human health , including through the food chain , and on the environment as a whole are felt through concentrations in ambient air and deposition . The accumulation of these substances in soils and the protection of surface water should be taken into account .


The figure obtained , multiplied by 12 and rounded up to the next whole number , shall constitute the number of months on which compensatory interest shall be applicable .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The obtained figure is multiplied by twelve and then rounded up to a whole number . The result is the number of months during which compensatory interest is charged .


The first , marked 'original` and bearing the number 1 , shall be issued to the applicant and the second , marked 'copy for the competent authority` and bearing the number 2 , shall be kept by the issuing authority , whereas the third marked 'copy for the customs supervising office` and bearing the number 3 will be sent to the customs supervising office , as defined in Article 13 .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The second copy , marked "copy of competent authorities" and the number 2 , is kept by the authorities issuing the license . The third copy , marked "copy of the customs office of control" and the figure 3 , shall be sent to the customs office of control as defined in Article 13 .


The first 37 patients were started at 400 mg , the protocol was subsequently amended to allow higher dosing and the remaining 223 patients were started at 600 mg .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The first 37 patients started treatment at 400 mg . The protocol was then amended to allow for a higher dosage , and the next 223 patients received an initial dose of 600 mg .


The first 77 patients were started at 400 mg , the protocol was subsequently amended to allow higher dosing and the remaining 158 patients were started at 600 mg .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The first 77 patients started treatment at 400 mg . Subsequently , the protocol was amended to allow a higher dosage and the following 158 patients started treatment at 600 mg .


The first perceptible analgesic effect occurred in 7 -13 minutes , with clinically meaningful analgesia demonstrated in 23-39 minutes and a peak effect within 2 hours following administration of single doses of 40 mg IV or IM Dynastat .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The first sensation of analgesia appeared within 7-13 minutes , with clinically significant analgesia onset within 23-39 minutes . Peak activity occurred within 2 hours of receiving a single 40 mg IV or IM dose of Dynastat .


The following dose regimen is recommended for titration , although in all cases the physician should take into account the clinical need of the patient , age and concomitant illness .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The following dosage regimen is recommended for titration . However , the physician must always take into account the clinical needs of the patient , his age and concomitant illnesses .


The following related adverse reactions were listed below by system organ class and within each frequency grouping , adverse reactions are presented in order of decreasing seriousness: common ( 1/ 100 to < 1/ 10 ) ; uncommon ( 1/ 1 , 000 to < 1/ 100 ) ; rare ( 1/ 10 , 000 to < 1/ 1 , 000 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The following side effects have been classified below by system organ class . Within each frequency grouping , undesirable effects are presented in order of decreasing seriousness: common ( 1/100 , <1/10 ) ; uncommon ( 1/1000 , <1/100 ) ; rare ( 1 / 10 , 000 <1 / 1 , 000 ) .


The import , sale , supply and/ or use of this veterinary medicinal product is or may be prohibited in certain Member States on the whole or part of their territory , see package leaflet for further information .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

A Member State may prohibit the import , sale , supply and / or use of this veterinary medicinal product in all or part of its territory . Read the instructions for use for more information .


The imported product and the Community product were both perceived by consumers as alternatives to satisfy a particular want or demand , in this respect the differences identified by certain exporters and importers were simply minor variations .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The imported product and the Community product were both considered by consumers as alternative products intended to satisfy a specific demand . From this point of view , the differences reported by some exporters and importers were only minor variations .


The incidence of thrombotic/ thromboembolic events observed in clinical trials was similar between romiplostim and placebo , and an association between these events and elevated platelet counts was not observed .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The incidence of thromboembolic events observed in clinical studies was similar between romiplostim and placebo . No link between these events and a high platelet count has been found .


The incidence rates for moderate and severe pain after Optaflu vaccination are similar to those of egg-derived influenza vaccines; however a slightly increased risk for mild short-lasting injection site pain was observed with Optaflu in the subgroup of elderly vaccinees ( 8% compared to 6% with egg-derived influenza vaccine ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The incidence rates for moderate and severe severe pain following vaccination with Optaflu are similar to rates obtained with influenza vaccines derived from eggs . However , a slightly higher risk of mild , short-lived injection site pain was observed with Optaflu in the vaccinated elderly subgroup ( 8% versus 6% with egg-derived influenza vaccines ) . .


The initial contribution of any member which becomes a Party to this Agreement after its entry into force shall be assessed by the Council on the basis of the share allotted to that member and of the unexpired portion of the year in question , but the assessments made upon the other members for that calendar year shall not be altered .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The initial share of each member who becomes a party to this agreement after its entry into force is set by the board according to the share allotted to this member and the fraction of the remaining year . However , the quotas set for the other members for the current calendar year are not changed .


The injury suffered by the Community industry during this period was caused by dumped imports originating in the Czech Republic , Malaysia , Russia , the Republic of Korea and Slovakia , and therefore definitive anti-dumping measures were imposed against these countries in August 2002 ( 12 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The injury suffered by the Community industry during this period was caused by dumped imports from Malaysia , the Republic of Korea , Russia , Slovakia and the Czech Republic . Therefore , definitive anti-dumping measures were imposed on those countries in August 2002 ( 12 ) .


The level of these duties , which were re-imposed as late as December 1999 following a full "sunset" review , ranged up to 154 , 72 % for one company in China .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

These duties were re-imposed in December 1999 in the context of an expiry review . For a company in China the duty amounted to 154 . 72% .


The main measure of effectiveness was based on the change in the questionnaire score before the study began and after six months of treatment .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

These studies were based on a questionnaire specially designed to measure sexual interest and activity by recording the number of satisfactory intercourse over a four-week period . The main measure of effectiveness was based on the change in the score obtained on the questionnaire before the start of the study and after six months of treatment with this medicine .


The main measure of effectiveness was the change in the speed at which the patients made saccadic horizontal eye movements after a year , but the study also looked at other neurological symptoms such as the patients ability to swallow and their intellectual function .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The main measure of effectiveness was the change in the rate at which patients jerked the eyes horizontally after one year of treatment . The study also looked at other neurological symptoms such as patients' ability to swallow or their intellectual function .


The maintenance effect on typical absence seizures remains unclear , thus a warning will be included in the SPC stating that In children taking lamotrigine for the treament of typical absence seizures , efficacy may not be maintained in all patients .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The continued effect on typical absence seizures is still unclear . A warning should therefore be added to the SPC , stating that "In children taking lamotrigine for the treatment of typical absence seizures , efficacy may not be maintained in all patients" .


The majority of LVEF decreases ( greater than 60% ) were observed during the first nine weeks of treatment , however limited data was available for long term exposure .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The majority ( over 60% ) of the decreases in LVEF were seen within the first nine weeks of treatment . However , the data available regarding longer exposure times are limited .


The maximum recommended dosing frequency is once per day , but continuous daily use of 10 or 20 mg tadalafil is not recommended .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The maximum recommended dose is once a day . Continued daily use of 10 mg or 20 mg tadalafil tablets , however , is not recommended .


The maximum reduction in blood pressure is generally attained 4 to 8 weeks after the start of treatment and is sustained during long-term therapy .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In general , the maximum reduction in blood pressure is achieved 4 to 8 weeks after the start of treatment . It persists during long-term treatment .


The maximum reduction in blood pressure is generally attained 4-8 weeks after the start of treatment and is sustained during long-term therapy .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In general , the maximum reduction in blood pressure is obtained 4 to 8 weeks after the start of treatment . It persists during long-term treatment .


The maximum volume which can be measured with the dispensing syringe is 5 ml and therefore steps 3-5 must be repeated for dosage volumes greater than 5 ml .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The maximum volume that can be withdrawn at one time is 5 ml . Steps 3 to 5 should be repeated to withdraw volumes greater than 5 ml .


The modulated infrared beams then enter the infrared detectors , which are double layer transmission detectors with a front , and a rear chamber each filled with one of the isotopicly pure gases ( 13CO2 or 12CO2 , respectively ) to be measured .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The modulated infrared rays are then collected by the detectors . These are double-layer transmission detectors comprising a front chamber and a rear chamber each filled with one of the isotopically pure gases to be measured respectively ( 13CO2 and 12CO2 ) .


The most commonly reported adverse reactions are bleedings occurring in total in approximately 14% of patients; the frequency of major bleeds ( including wound site bleedings ) is less than 2% .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The most frequently reported side effects were bleeding , occurring in total in about 14% of patients . The frequency of major bleeding events ( including bleeding from the wound ) was less than 2% .


The most likely manifestations of overdose are expected to be hypotension and tachycardia; bradycardia might also occur from overdose .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In the event of overdose , the most likely clinical signs would be hypotension and tachycardia . Bradycardia could also occur .


The need for a booster dose of hepatitis B vaccine in healthy individuals who have received a full primary vaccination course has not been established; however some official vaccination programmes currently include a recommendation for a booster dose of hepatitis B vaccine and these should be respected .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The need for a booster dose of hepatitis B vaccine in healthy subjects who have received a full primary vaccination has not been established . However , some official vaccination programs include a recommendation for a booster dose of the hepatitis B vaccine , which should be observed .


The nonclinical toxicity profile of mycophenolate mofetil appears to be consistent with adverse events observed in human clinical trials which now provide safety data of more relevance to the patient population ( see section 4 . 8 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

This toxicity profile of mycophenolate mofetil in animals corresponds to the side effects observed in clinical trials . The safety data in humans are thus confirmed ( see section 4 . 8 ) .


The number of applications being processed using the mutual recognition procedure is increasing and this trend is expected to continue , principally because from 1 January 1998 parallel applications for a product authorised in another Member State will have to be processed using mutual recognition , in accordance with the legislation .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The number of requests processed through the mutual recognition procedure is increasing . This trend is expected to continue , mainly due 38 to the fact that , from 1 January 1998 , applications for a product authorized in another Member State will have to be processed by mutual recognition , in accordance with the law .


The observed incidence of antibody positivity in an assay may be influenced by several factors including sample handling , concomitant medications and underlying disease , therefore , comparison of the incidence of antibodies to other products may be misleading .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The observed incidence of a positive antibody test can be influenced by several factors including sample handling , concomitant treatments , and underlying disease . Therefore , the comparison between the incidences of antibodies directed against other products can be misleading .


The occurrence of avian influenza infections with virus of low pathogenicity has considerably decreased in the last few months; however it appears appropriate to prolong the vaccination programme for a further six months protecting the population against a re-introduction of the infection .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Avian influenza infections with weakly pathogenic viruses have declined significantly in recent months . However , it seems appropriate to extend the vaccination program for a further six months in order to protect the stocks against re-infection .


The pharmacokinetic properties of amprenavir following co-administration of Telzir with ritonavir have been evaluated in healthy adult subjects and HIV-infected patients and no substantial differences were observed between these two groups .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Following co-administration of fosamprenavir and ritonavir , the pharmacokinetics of amprenavir have been evaluated in healthy adult subjects and in patients with HIV infection . No significant difference was observed between these two groups .


The powder and solvent are mixed just before administration , and the resulting suspension is given directly into the mouth of the baby using the oral syringe provided .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

If the medicine is administered as a powder and a solvent , these should be mixed just before the administration of the vaccine . The resulting suspension should be poured directly into the infant's mouth using the oral applicator provided .


The powder should be mixed with the solvent provided just before use , and the contents of more than one vial of powder can be dissolved in on vial of solvent if needed .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The powder should be mixed immediately before use with the solvent provided . It is possible , if necessary , to mix the contents of several vials of powder with a single vial of solvent .


The primary pathways of metabolism in man are by alcohol dehydrogenase and by glucuronidation to produce the 5 -carboxylic acid and 5 - glucuronide which account for about 66% of the administered dose .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

In humans , abacavir is primarily metabolized by alcohol dehydrogenase and glucuronyl transferase . This leads to the formation of 5 -carboxylic acid and 5-glucuronide which account for approximately 66% of the administered dose .


The principal adverse reactions associated with the administration of mycophenolate in combination with ciclosporin and corticosteroids include diarrhoea , leucopenia , sepsis and vomiting and there is evidence of a higher frequency of certain types of infections ( see section 4 . 4 ) .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The main adverse reactions associated with the administration of mycophenolate in combination with ciclosporin and corticosteroids are: diarrhea , leukopenia , generalized infections and vomiting . In addition , some infections appear to occur with increased frequency ( see section 4 . 4 ) .


The proceeding was initiated as a result of a complaint lodged on 6 July 2000 by SRAM Deutschland GmbH , representing a major proportion of the Community production of IGH .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The proceedings were initiated on July 6 , 2000 by SRAM Deutschland GmbH . This company accounts for a significant part of the gear hub production in the Community .


The product concerned by this investigation is the same as in the previous investigations , namely synthetic staple fibres of polyester , not carded , combed or otherwise processed for spinning; it is commonly referred to as polyester synthetic fibres ( PSF ) and currently classifiable within CN code 5503 20 00 .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The product under consideration is the same as in the previous investigations , namely synthetic staple fibers of polyester , not carded , combed or otherwise processed for spinning . It is generally referred to as "synthetic polyester fibers" and currently falls within CN code 5503 20 00 .


The programme calls for the CAP to be applied in that region and provides for special measures to be adopted , in particular to improve the conditions in which agricultural products are produced and marketed there and to mitigate the effects of its exceptional geographical situation and constraints as since recognised in Article 299 ( 2 ) of the Treaty .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

This program is based on the application of the CAP in this region and foresees the adoption of specific measures . It includes measures to improve the production and marketing conditions for the region's agricultural products and to mitigate the effects of its exceptional geographical location and constraints , which have now been recognized in Article 299 ( 2 ) of the Treaty .


The purchaser must , before withdrawing the oil , pay to the intervention agency the provisional amount of the selling price , which shall be calculated by multiplying the quantity indicated as contained in the lot by the price offered for the lot .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Before withdrawing the oil , the buyer is required to pay the intervention agency the provisional amount of the selling price . The provisional amount is calculated by multiplying the quantity indicated as contained in the lot by the price offered for that lot .


The recommended dose of Humira for adult patients is an initial dose of 80 mg administered subcutaneously , followed by 40 mg subcutaneously given every other week starting one week after the initial dose .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The recommended dose of Humira to start treatment in adults is 80 mg subcutaneously . The dosage will continue one week later with 40 mg subcutaneously every other week .


The referral procedure was initiated with UK as the reference member state ( RMS ) , due to concerns raised by the concerned member states Greece , Poland and Spain regarding major safety and efficacy issues and the immunological protection correlates , they considered the submitted clinical documentation insufficient to establish the clinical efficacy and safety of Menitorix , considering the product to be an entirely new conjugated , bivalent vaccine .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The referral procedure has been launched , with the United Kingdom as Reference Member State ( RMS ) , due to concerns expressed by the Member States concerned , Greece , Poland and Spain , about major issues in terms of efficacy and safety and the associated uncertainties in terms of immune protection . These states considered that the clinical literature submitted was insufficient to establish the clinical efficacy and safety of Menitorix , as this product is an entirely new conjugate equivalent vaccine .


The residual medicinal product must be flushed in the administration tubing as rapid infusion of Busilvex has not been tested and is not recommended .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Residual product from the tubing should not be injected quickly . As the rapid infusion of Busilvex has not been tested , it is not recommended .


The risk of myopathy during treatment with HMG-CoA reductase inhibitors is increased with concurrent administration of ciclosporin , fibric acid derivatives , macrolide antibiotics including erythromycin , azole antifungals , or niacin and on rare occasions has resulted in rhabdomyolysis with renal dysfunction secondary to myoglobinuria .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The risk of myopathy during treatment with HMG-CoA reductase inhibitors increases when combined with ciclosporin , fibrates , macrolide antibiotics including erythromycin , azole antifungals or nicotinic acid . In rare cases , this combination has caused rhabdomyolysis with kidney dysfunction secondary to myoglobinuria .


The safety and efficacy of Aldurazyme in patients with renal or hepatic insufficiency have not been evaluated and no dosage regimen can be recommended in these patients .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The safety and efficacy of Aldurazyme have not been evaluated in patients with hepatic or renal impairment . No dosage regimen can be recommended in these patients .


The safety and efficacy of Kepivance in children and adolescent patients have not been established , Kepivance should not be used in children or adolescents until further data become available .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The safety and effectiveness of Kepivance have not been established in children and adolescents . Kepivance should not be used in children or adolescents without further data .


The safety of this medicinal product for use in human pregnancy has not been established in controlled clinical trials and therefore should only be given with caution to pregnant women and breast-feeding mothers .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

The safety of this medicine in pregnant women has not been established through controlled clinical trials . Therefore , this drug should be prescribed with caution in pregnant or breastfeeding women .


The same Articles provide that it is also important to ensure equilibrium and the natural development of prices and trade on the markets in cereals and rice and , furthermore , to take into account the economic aspect of the proposed exports , and the need to avoid disturbances on the Community market .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

According to the same articles , a balanced situation and natural price and trade development must be ensured on the grain and rice markets . Account should also be taken of the economic aspects of the planned exports and the need to avoid market disruption in the Community .


The se increases may be partly due to competitive inhibition of the elimination of bile salts from hepatocytes but other mechanisms , which have not been clearly established , are probably also involved in the occurrence of liver dysfunction .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

This increase in serum transaminase activity may be partly related to competitive inhibition of bile salt elimination by hepatocytes . Other mechanisms , which have not yet been clearly determined , could also be involved when a disturbance in liver functions appears .


The sole cooperating company in Israel , Jolybar , slits , sheets and converts purchased PET film and sells it as products which fall under the same CN codes as the product concerned , but is generally not of Indian origin and therefore it cannot be considered the product concerned .
The above sentence is very complicated. Please provide me a simplified synonymous version consisting of multiple sentences:

Jolybar , the only cooperating Israeli company , cuts and processes purchased PET film and sells them as products which fall under the same CN code as the product concerned , but are generally not of Indian origin . It cannot therefore be considered that this is the product concerned .