passages.id: split_8_test_2027_passage
passages.type: progene_text
passages.text: Expression of C / EBPalpha is suppressed at the translational level by interaction of the poly ( rC ) - binding protein hnRNP E2 with CEBPA mRNA , and ectopic expression of hnRNP E2 in myeloid precursor cells down - regulates both C / EBPalpha and G - CSF - R and leads to rapid cell death on treatment with G-CSF ( encoded by CSF3 ) .