passages.id: split_8_test_2123_passage
passages.type: progene_text
passages.text: Accordingly , a number of population studies have explored the association of ischaemic heart disease with gene polymorphisms of the inflammatory molecules tumour necrosis factors ( TNF ) alpha and beta , transforming growth factors ( TGF ) beta1 and 2 , interleukin ( IL ) 1 and its receptor antagonist ( IL 1ra ) , CD14 ( the receptor for lipopolysaccharide ) , P and E selectins , and platelet endothelial cell adhesion molecule ( PECAM ) 1 .