passages.id: split_8_test_1578_passage
passages.type: progene_text
passages.text: Integrin signals are relayed in part by focal adhesion kinase ( FAK ) activation and the formation of a transient signaling complex initiated by Src homology 2 ( SH2 ) - dependent binding of Src family protein - tyrosine kinases to the FAK Tyr - 397 autophosphorylation site .