passages.id: split_8_test_1380_passage
passages.type: progene_text
passages.text: Two of these GEFs , MR-GEF ( M-Ras-regulated GEF , KIAA0277 ) and PDZ-GEF ( KIAA0313 ) bound specifically to nucleotide - free Rap1 and Rap1 / Rap2 , respectively .