passages.id: split_8_test_2905_passage
passages.type: progene_text
passages.text: In multivariate Cox proportional hazard models , heart failure / systolic dysfunction ( hazard ratio 2.91 ; 95 % CI 1.17 - 7.26 ; p = 0.02 ) , high levels of D-dimer on OAT ( top vs. lower two quartiles ) ( hazard ratio 4.78 , 95 % CI 1.39 - 16.41 ; p = 0.01 ) and t-PA antigen levels ( continuous variable ) ( hazard ratio 1.09 ; 95 % CI 1.01 - 1.17 ; p = 0.02 ) were significantly associated with combined cardiovascular events .