passages.id: split_8_test_862_passage
passages.type: progene_text
passages.text: Indeed , comparative studies with an RsmC (-) mutant , an RsmA ( - ) mutant , and an RsmA ( - ) RsmC ( - ) double mutant have revealed that the negative effects on exoprotein production and virulence are due to the cumulative regulatory effects of RsmC on rsmA and rsmB .