passages.id: split_8_test_895_passage
passages.type: progene_text
passages.text: In HeLa cells , the JNKK2 - JNK1 fusion protein showed significant JNK activity , which was comparable with that of JNK1 activated by many stimuli and activators , including EGF , TNF-alpha , anisomycin , UV irradiation , MEKK1 , and small GTP binding proteins Rac1 and Cdc42Hs .