passages.id: split_8_test_694_passage
passages.type: progene_text
passages.text: Dibutyryl cAMP and forskolin had little or no effect on HEF1 phosphorylation , and the protein kinase A inhibitor H89 failed to detectably inhibit the response to calcitonin , indicating that the G(s) / cAMP / protein kinase A pathway does not mediate the calcitonin effect .