passages.id: split_8_test_512_passage
passages.type: progene_text
passages.text: The open reading frame and some surrounding sequence also have significant homology with the breakpoint enhancer elements , which also contain open reading frames , implicated in the HPFH-1 / 2 and HPFH-6 deletional forms of the human syndrome , hereditary persistence of foetal haemoglobin ( HPFH ) .