passages.id: split_8_test_3380_passage
passages.type: progene_text
passages.text: Moreover , APC interacts with IQGAP1 , an effector of Rac1 and Cdc42 , and APC - stimulated guanine nucleotide exchange factor ( Asef ) , a Rac1 - specific guanine nucleotide exchange factor ( GEF ) .