passages.id: split_8_test_1764_passage
passages.type: progene_text
passages.text: Because residual FAK protein in ISIS 15421 - treated A549 cells was highly phosphorylated at the Tyr - 397 / Src homology ( SH ) 2 binding site , expression of the FAK COOH - terminal domain ( FRNK ) was also used as an inhibitor of FAK function .