passages.id: split_8_test_1547_passage
passages.type: progene_text
passages.text: Suppression of interleukin 12 ( IL-12 ) production by dendritic cells ( DCs ) has been hypothesized to be a principal mechanism underlying the biological action of interferon ( IFN ) - beta used for treatment of multiple sclerosis ( MS ) , a chronic inflammatory disease of the central nervous system with possible autoimmune origin .