passages.id: split_8_test_2901_passage
passages.type: progene_text
passages.text: Established clinical risk factors and levels of prothrombin fragment 1+2 ( F1+2 ) , thrombin - antithrombin complexes ( TAT ) , D-dimer , tissue plasminogen activator ( t-PA ) and plasminogen activator inhibitor 1 ( PAI-1 ) antigen and activity , before and during OAT ( after 3.9 +/- 0.7 months ; INR 2.57 +/- 0.57 ) were determined .