passages.id: split_8_test_1889_passage
passages.type: progene_text
passages.text: The significant increase in the concentration of homocysteine in children with Type 1 diabetes and arterial hypertension indicates that this group is particularly exposed to early atherosclerotic changes , independently of metabolic control and the parameters of lipid metabolism , and requires the implementation of treatment aimed at reducing the blood concentration of homocysteine .