passages.id: split_6_test_1311_passage
passages.type: progene_text
passages.text: Transient transfection experiments with CaCo-2 and HepG2 cells indicated that the 315 - bp fragment contained an intestine - specific enhancer , and analysis of the DNA sequence revealed putative binding sites for the tissue - specific transcription factors hepatocyte nuclear factor 3beta , hepatocyte nuclear factor 4 , and CAAT enhancer - binding protein beta .