passages.id: split_6_test_1663_passage
passages.type: progene_text
passages.text: Our data furthermore indicate that an eventual therapy with chemical chaperones that restores the routing of AQP2 mutants to the apical membrane of collecting ducts cells might relieve NDI in patients encoding AQP2 - A147T , and to a lesser extent AQP2 - T126M and AQP2 - G64R , but not in patients encoding AQP2 - N68S , AQP2 - R187C or AQP2 - S216P .