passages.id: split_6_test_2911_passage
passages.type: progene_text
passages.text: IFN - DCs secreted large amounts of the inflammatory cytokines IL-6 , IL-10 , TNF-alpha , IL-1beta , and IL-18 , and promoted a Th1 response that was independent of IL - 12p70 and IL - 18 , but substantially inhibited by IFN-alpha neutralization .