passages.id: split_6_test_3125_passage
passages.type: progene_text
passages.text: To address how transforming growth factor ( TGF ) - beta and oncogenic H-ras signal transduction pathways interact with each other in the malignant progression of breast epithelial cells , we investigated the role of TGF-beta signaling pathway in invasive and migrative properties of H-ras - transformed MCF10A human breast epithelial cells in this study .