passages.id: split_6_test_2256_passage
passages.type: progene_text
passages.text: As previously demonstrated in vitro ( L. Decker et al. , 2000 , Mol. Cell. Neurosci. 16 , 422 - 439 ) , these data illustrate the involvement of PSA and NCAM in neural precursor motility and differentiation in the normal and injured central nervous system , suggesting distinct roles for these two molecules under pathophysiological conditions .