passages.id: split_6_test_710_passage
passages.type: progene_text
passages.text: Transient tyrosine phosphorylation of Crk in fibroblast growth factor-2 - stimulated endothelial cells was dependent on the juxtamembrane tyrosine residue 463 in FGFR-1 , and a Crk SH2 domain precipitated FGFR-1 via phosphorylated Tyr - 463 , indicating direct complex formation between Crk and FGFR-1 .