passages.id: split_6_test_3194_passage
passages.type: progene_text
passages.text: Utilizing a mouse cDNA array containing 514 chemokine and chemokine related genes , the loss of MCP-1 was observed to cause a significant upregulation of nine genes ( Decorin , Persephin , IL-1beta , MIP-2 , MSP , IL1ra , CCR5 , CCR3 , IL-11 ) and significant downregulation of two genes ( CCR4 and CD3Z ) in acute wounds .