passages.id: split_6_test_3456_passage
passages.type: progene_text
passages.text: We found that polyI : C , LPS , R848 , S-28463 , and ODN2006 , which are specifically recognized by TLR3 , TLR4 , TLR7 / 8 , and TLR9 in mammals , induced substantial amounts of type I interferon ( IFN ) and interleukin-6 ( IL-6 ) in freshly prepared chicken splenocytes .