passages.id: split_6_test_2629_passage
passages.type: progene_text
passages.text: To study the effects of palmitoylation on ASGP-R activity and function , we generated four types of stably transfected cell lines in SK-Hep-1 hepatoma cells , expressing wild - type , or partially or completely palmitoylation - defective ASGP - Rs containing Cys - to - Ser mutations in either one or both subunits .