passages.id: split_6_test_1846_passage
passages.type: progene_text
passages.text: These two new chlorofluoroquinolones were as effective as or more effective than ciprofloxacin against all experimental infections evaluated , not only against gram - negative bacteria , such as Escherichia coli or P. aeruginosa , but also against gram - positive pathogens , such as Staphylococcus aureus or Streptococcus pneumoniae .