passages.id: split_5_test_2174_passage
passages.type: progene_text
passages.text: We show that ADF is a much more potent actin - depolymerizing agent than cofilin : the maximum level of depolymerization at pH 8 by ADF is about 20 microM compared to 5 microM for cofilin , but little depolymerization occurs at pH 6.5 with either protein .