passages.id: split_5_test_3303_passage
passages.type: progene_text
passages.text: Relative to type I IFNs used alone , the addition of type II IFN caused enhanced expression not only of many of the genes correlated with the direct antiviral state but also of genes involved in (1) antigen presentation to cytotoxic T lymphocytes ( CTLs ) , (2) macrophage , natural killer ( NK ) , and T helper 1 ( Th1 ) cell recruitment and activation , (3) complement system function , (4) apoptosis , and ( 5 ) ISGs with unknown functions .