passages.id: split_5_test_574_passage
passages.type: progene_text
passages.text: In this study we describe that platelet - derived growth factor ( PDGF ) , 12-O-tetradecanoyl-phorbol-acetate ( TPA ) , and forskolin induced CREB ( cAMP - responsive element - binding protein ) Ser-133 phosphorylation with comparable magnitude and kinetics in NIH 3T3 cells .