passages.id: split_5_test_2995_passage
passages.type: progene_text
passages.text: Assays of DNA synthesis , cell proliferation , and migration were performed in response to sc - uPA , ATF , kringle , and CTF in the presence and absence of the plasmin inhibitors epsilon - aminocaproic acid ( EACA ) and aprotinin , the Galphai inhibitor pertussis toxin , and the mitogen - activated protein kinase 1 ( the upstream regulator of the extracellular - signal regulated kinase [ ERK ] ) inhibitor PD98059 .