passages.id: split_5_test_1342_passage
passages.type: progene_text
passages.text: In this case - control study , involving 142 coronary artery disease ( CAD ) patients and 102 controls , we have typed six genetic polymorphisms in three homocysteine metabolizing genes and examined their relationship to the incidence of CAD , tHcy levels , and lowering of tHcy levels in response to folic acid supplementation .