passages.id: split_5_test_323_passage
passages.type: progene_text
passages.text: Members of the mitogen activated protein ( MAP ) kinase family , extracellular signal - regulated kinase , stress - activated protein kinase-1 / c-Jun NH2 - terminal kinase , and p38 , are central elements that transduce the signal generated by growth factors , cytokines , and stressing agents .