passages.id: split_5_test_1830_passage
passages.type: progene_text
passages.text: Using deletion mutants of the 5' - flanking region of the p75TNFR gene , we were able to identify a putative DNA binding site for the transcription factor nuclear factor - interleukin-6 ( NF-IL-6 ) to be responsible for the transcriptional upregulation of the p75TNFR gene under conditions of hypoxia and reoxygenation .