passages.id: split_5_test_2927_passage
passages.type: progene_text
passages.text: We describe a method for detection of protein - protein interactions among HLH proteins in vivo in which dimerization through the HLH motif reconstructs a hybrid transcription factor containing the DNA - binding domain of yeast GAL4 linked to one HLH motif and the activation domain of VP-16 linked to another .