passages.id: split_5_test_872_passage
passages.type: progene_text
passages.text: Upon binding to FGFR1 , basic FGF stimulates cytosolic form of phospholipase A2 ( cPLA2 ) , phospholipase C-gamma1 ( PLC-gamma1 ) and phospholipase D ( PLD ) , the key enzymes for the production of various lipid second messengers , in a tyrosine kinase - dependent manner .