passages.id: split_5_test_2230_passage
passages.type: progene_text
passages.text: Here we assess the significance of the Arg-95 to Trp gain - of - function mutation in the v-Src SH3 domain through comparisons of Src -/- fibroblasts transformed with either Prague C v - Src or a point mutant ( v - Src - RT ) containing a normal ( Arg - 95 ) SH3 domain .