passages.id: split_5_test_3535_passage
passages.type: progene_text
passages.text: LPS stimulation can significantly increase the phosphorylation of ERK(1/2 ) , p38 MAPK and JNK in the epithelial cells of airway and activate the MAPK transduction pathway , thereby can activate the downstream signal transduction pathway , and can ultimately result in the release of cytokines by the epithelial cells of airway .