passages.id: split_5_test_2381_passage
passages.type: progene_text
passages.text: After a 4 - week run - in placebo period , patients were randomized to : atenolol 50 mg / day ; trandolapril 2 mg / day ; verapamil 240 mg / day or verapamil 180 + trandolapril 2 mg / day combination ; forced double - dose titration was carried out at the 4th week .