passages.id: split_5_test_1730_passage
passages.type: progene_text
passages.text: Relative to APV alone , RTV co - administration resulted in a 3.3 - to 4 - fold and 10.84 to 14.25 - fold increase in the geometric least - square ( GLS ) mean area under the plasma concentration - - time curve ( AUC(tau,ss) ) and minimum concentration ( C(min,ss ) ) , respectively .