passages.id: split_5_test_3256_passage
passages.type: progene_text
passages.text: We performed this study to determine the relationship between activation of nuclear factor ( NF ) - kappaB and inhibition of keratinocyte growth by anthralin , which not only might be useful for a better understanding of the role of NF-kappaB in the pathogenesis of psoriasis , but also indicate whether the inflammatory reaction induced by anthralin is inseparable from its antipsoriatic activity .