passages.id: split_4_validation_1141_passage
passages.type: progene_text
passages.text: These data suggest that the induction of urokinase by HGF / SF is regulated by a Grb2 / Sos1 / Ha-Ras / c-Raf / RhoA / Mek1 / Erk2 / c-++ + Jun - dependent mitogen - activated protein kinase pathway .