passages.id: split_4_validation_1322_passage
passages.type: progene_text
passages.text: When administered to relaxin - deficient mice ( which undergo an age - dependent progression of organ fibrosis ) over a 4 month treatment period , mouse relaxin was able to significantly inhibit the progression of collagen accumulation in several organs including the lung , kidney , testis , and skin ( all p < 0.05 vs untreated group ) , consistent with the actions of H2 relaxin .