text_1: 对于 并 无可 靶向 的 驱动 突变 的 晚期 非小 细胞 肺癌 ( NSCLC ) 患者 , 其 一线 治疗 已 取得 实质性 进展 .
  
text_2: substantial progress has been made in the first @-@ line treatment of patients with advanced non @-@ small @-@ cell lung cancer ( NSCLC ) without driver alterations that can be targeted .
  