text_1: 新 的 临床试验 设计 方法 ( 如 根据 癌症 的 驱动 突变 决定 患者 接受 不同 治疗 的 篮式 和 伞式 研究 ) 已 获得 一些 偶然 的 成功 , 但 总体而言 结果 令人 失望 124 .
  
text_2: new approaches in clinical @-@ trial design - such as basket and umbrella studies , in which patients are directed to different therapies by virtue of the driver mutations of their cancers - have shown some occasional successes but overall have been disappointing.124
  