text_1: 60-year-old woman just had a pulmonary embolus and deep vein thrombosis a few months back.  She has Factor V Leiden, homozygous and she wanted me to give her more information for her children.  I (investigator) said, "So the question is . . . "  She said, "The question is prophylactic anticoagulation for them and information for their kids (grandchildren of the patient)."
text_2: What are the implications for children of a patient homozygous for Factor V Leiden?