sentences.id: IEPA.d170.s410
sentences.origID: 166
sentences.text: Influence of obesity and menopausal status on serum leptin, cholecystokinin, galanin and neuropeptide Y levels
sentences.id: IEPA.d170.s410.e0
sentences.origID: 363
sentences.text: leptin
sentences.id: IEPA.d170.s410.e1
sentences.origID: 364
sentences.text: neuropeptide Y
sentences.id: IEPA.d170.s411
sentences.origID: 167
sentences.text: Obesity occurs in 60% of women after menopause and is characterized by an excess of adipose tissue that depends on several orexigenic (neuropeptide Y (NPY) stimulates carbohydrate ingestion, galanin stimulates fat intake) and anorectic (leptin, cholecystokinin (CCK)) factors
sentences.id: IEPA.d170.s411.e0
sentences.origID: 365
sentences.text: neuropeptide Y
sentences.id: IEPA.d170.s411.e1
sentences.origID: 366
sentences.text: leptin
sentences.id: IEPA.d170.s412
sentences.origID: 168
sentences.text: Both leptin and insulin can reduce hypothalamic NPY production and secretion
sentences.id: IEPA.d170.s412.e0
sentences.origID: 367
sentences.text: leptin
sentences.id: IEPA.d170.s412.e1
sentences.origID: 368
sentences.text: NPY
sentences.id: IEPA.d170.s412.i0
sentences.e1: IEPA.d170.s412.e0
sentences.e2: IEPA.d170.s412.e1
sentences.type: PPI
sentences.id: IEPA.d170.s413
sentences.origID: 169
sentences.text: We investigated basal levels of serum leptin, CCK, galanin and NPY in 16 non-obese premenopausal women, in 15 obese premenopausal women (body mass index (BMI) 34.6 +/- 1.3 SD) and in ten obese postmenopausal women (BMI 34.7 +/- 1.5 SD) to determine the relationship between obesity, menopause and these neuropeptides
sentences.id: IEPA.d170.s413.e0
sentences.origID: 369
sentences.text: leptin
sentences.id: IEPA.d170.s413.e1
sentences.origID: 370
sentences.text: NPY
sentences.id: IEPA.d170.s414
sentences.origID: 170
sentences.text: Significantly increased leptin and galanin levels in postmenopausal obese women coupled with decreased NPY levels revealed some changes in the neuropeptides regulating eating behavior, which may be the reason for the onset of postmenopausal obesity
sentences.id: IEPA.d170.s414.e0
sentences.origID: 371
sentences.text: leptin
sentences.id: IEPA.d170.s414.e1
sentences.origID: 372
sentences.text: NPY