sentences.id: IEPA.d55.s139
sentences.origID: 257
sentences.text: After protein kinase C activity was functionally depleted by treating cells with phorbol 12-myristate 13-acetate for 24 hours, AVP did not augment IL-1beta-induced NO production
sentences.id: IEPA.d55.s139.e0
sentences.origID: 559
sentences.text: protein kinase C
sentences.id: IEPA.d55.s139.e1
sentences.origID: 560
sentences.text: AVP
sentences.id: IEPA.d55.s140
sentences.origID: 258
sentences.text: The effect of AVP was also inhibited in the presence of the protein kinase C inhibitor calphostin C
sentences.id: IEPA.d55.s140.e0
sentences.origID: 561
sentences.text: AVP
sentences.id: IEPA.d55.s140.e1
sentences.origID: 562
sentences.text: protein kinase C
sentences.id: IEPA.d55.s140.i0
sentences.e1: IEPA.d55.s140.e0
sentences.e2: IEPA.d55.s140.e1
sentences.type: PPI
sentences.id: IEPA.d55.s141
sentences.origID: 259
sentences.text: The addition of AVP increased protein kinase C activity in cardiac myocytes, and its effect was significantly inhibited in the presence of calphostin C
sentences.id: IEPA.d55.s141.e0
sentences.origID: 563
sentences.text: AVP
sentences.id: IEPA.d55.s141.e1
sentences.origID: 564
sentences.text: protein kinase C
sentences.id: IEPA.d55.s141.i0
sentences.e1: IEPA.d55.s141.e0
sentences.e2: IEPA.d55.s141.e1
sentences.type: PPI
sentences.id: IEPA.d55.s142
sentences.origID: 260
sentences.text: These results support the hypothesis that the heart may be a target organ for AVP and that AVP modulates IL-1beta-induced iNOS expression in myocytes through the V1a receptor, which is mediated at least partially via activation of protein kinase C
sentences.id: IEPA.d55.s142.e0
sentences.origID: 565
sentences.text: AVP
sentences.id: IEPA.d55.s142.e1
sentences.origID: 566
sentences.text: AVP
sentences.id: IEPA.d55.s142.e2
sentences.origID: 567
sentences.text: protein kinase C
sentences.id: IEPA.d55.s142.i0
sentences.e1: IEPA.d55.s142.e1
sentences.e2: IEPA.d55.s142.e2
sentences.type: PPI