sentences.id: IEPA.d32.s66
sentences.origID: 479
sentences.text: Gamma-aminobutyric acid mediation of the inhibitory effect of nitric oxide on the arginine vasopressin and oxytocin responses to insulin-induced hypoglycemia
sentences.id: IEPA.d32.s66.e0
sentences.origID: 1082
sentences.text: oxytocin
sentences.id: IEPA.d32.s66.e1
sentences.origID: 1083
sentences.text: insulin
sentences.id: IEPA.d32.s66.i0
sentences.e1: IEPA.d32.s66.e0
sentences.e2: IEPA.d32.s66.e1
sentences.type: PPI
sentences.id: IEPA.d32.s67
sentences.origID: 480
sentences.text: Previous studies have demonstrated that the nitric oxide (NO) synthase inhibitor L-NAME exerts positive effects on the arginine vasopressin (AVP) and oxytocin (OT) responses to insulin-induced hypoglycemia, suggesting inhibitory actions of NO
sentences.id: IEPA.d32.s67.e0
sentences.origID: 1084
sentences.text: oxytocin
sentences.id: IEPA.d32.s67.e1
sentences.origID: 1085
sentences.text: insulin
sentences.id: IEPA.d32.s67.i0
sentences.e1: IEPA.d32.s67.e0
sentences.e2: IEPA.d32.s67.e1
sentences.type: PPI
sentences.id: IEPA.d32.s68
sentences.origID: 481
sentences.text: AVP and OT secretory patterns during insulin (0.15 IU/kg, i.v.)-tolerance tests (ITT) were examined in seven normal male subjects with (experimental tests) and without (control test) concomitant treatment with L-NAME (40 micrograms/kg injected plus 50 micrograms/kg infused, i.v.), the GABAergic agent sodium valproate (600 mg in three divided doses orally) or the combination of L-NAME and sodium valproate
sentences.id: IEPA.d32.s68.e0
sentences.origID: 1086
sentences.text: OT
sentences.id: IEPA.d32.s68.e1
sentences.origID: 1087
sentences.text: insulin
sentences.id: IEPA.d32.s69
sentences.origID: 482
sentences.text: Insulin-induced hypoglycemia increased by 2-fold (peak vs. baseline) plasma AVP and OT levels
sentences.id: IEPA.d32.s69.e0
sentences.origID: 1088
sentences.text: Insulin
sentences.id: IEPA.d32.s69.e1
sentences.origID: 1089
sentences.text: OT
sentences.id: IEPA.d32.s69.i0
sentences.e1: IEPA.d32.s69.e0
sentences.e2: IEPA.d32.s69.e1
sentences.type: PPI
sentences.id: IEPA.d32.s70
sentences.origID: 483
sentences.text: These data indicate a GABAergic mediation of the inhibitory modulation by NO of the AVP and OT responses to insulin-induced hypoglycemia
sentences.id: IEPA.d32.s70.e0
sentences.origID: 1090
sentences.text: OT
sentences.id: IEPA.d32.s70.e1
sentences.origID: 1091
sentences.text: insulin
sentences.id: IEPA.d32.s70.i0
sentences.e1: IEPA.d32.s70.e0
sentences.e2: IEPA.d32.s70.e1
sentences.type: PPI