sentences.id: IEPA.d150.s363
sentences.origID: 196
sentences.text: Possible central nervous system (CNS) mechanisms could mediate these responses in that leptin receptors are located on hypothalamic neurons that coexpress neuropeptide-Y (NPY) or proopiomelanocortin (POMC) and both peptides that have been implicated as mediators of the CNS action of leptin.
sentences.id: IEPA.d150.s363.e0
sentences.origID: 425
sentences.text: neuropeptide-Y
sentences.id: IEPA.d150.s363.e1
sentences.origID: 426
sentences.text: leptin
sentences.id: IEPA.d150.s363.i0
sentences.e1: IEPA.d150.s363.e0
sentences.e2: IEPA.d150.s363.e1
sentences.type: PPI
sentences.id: IEPA.d150.s364
sentences.origID: 197
sentences.text: Leptin has been demonstrated to decrease or down regulate NPY expression and increase POMC expression
sentences.id: IEPA.d150.s364.e0
sentences.origID: 427
sentences.text: Leptin
sentences.id: IEPA.d150.s364.e1
sentences.origID: 428
sentences.text: NPY
sentences.id: IEPA.d150.s364.i0
sentences.e1: IEPA.d150.s364.e0
sentences.e2: IEPA.d150.s364.e1
sentences.type: PPI