sentences.id: IEPA.d34.s80
sentences.origID: 373
sentences.text: Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue
sentences.id: IEPA.d34.s80.e0
sentences.origID: 853
sentences.text: leptin
sentences.id: IEPA.d34.s80.e1
sentences.origID: 854
sentences.text: uncoupling protein
sentences.id: IEPA.d34.s81
sentences.origID: 374
sentences.text: To establish the cell type expressing leptin, we also assessed the size and organization of lipid droplets, the ultrastructural features of mitochondria, and the presence or absence of uncoupling protein, a brown fat-specific marker
sentences.id: IEPA.d34.s81.e0
sentences.origID: 855
sentences.text: leptin
sentences.id: IEPA.d34.s81.e1
sentences.origID: 856
sentences.text: uncoupling protein
sentences.id: IEPA.d34.s82
sentences.origID: 375
sentences.text: In brown adipose tissue of lean animals, multilocular uncoupling protein (UCP)-positive brown adipocytes had typical brown mitochondria and were leptin-negative, both in fed and fasted conditions
sentences.id: IEPA.d34.s82.e0
sentences.origID: 857
sentences.text: uncoupling protein
sentences.id: IEPA.d34.s82.e1
sentences.origID: 858
sentences.text: leptin
sentences.id: IEPA.d34.s83
sentences.origID: 376
sentences.text: At the periphery of the interscapular brown adipose tissue depot, unilocular, UCP-negative adipocytes (mean diameter: 41.55 microns) with white-type mitochondria were observed, and these cells were leptin-positive
sentences.id: IEPA.d34.s83.e0
sentences.origID: 859
sentences.text: UCP
sentences.id: IEPA.d34.s83.e1
sentences.origID: 860
sentences.text: leptin
sentences.id: IEPA.d34.s84
sentences.origID: 377
sentences.text: In obese (db/db) animals, brown fat was composed mainly of small unilocular, UCP-positive adipocytes (mean diameter: 40.08 microns), which were also leptin-positive
sentences.id: IEPA.d34.s84.e0
sentences.origID: 861
sentences.text: UCP
sentences.id: IEPA.d34.s84.e1
sentences.origID: 862
sentences.text: leptin
sentences.id: IEPA.d34.s85
sentences.origID: 378
sentences.text: In summary, classical brown adipocytes differ from white adipocytes, not only by their morphology and UCP expression, but also by their apparent lack of detectable leptin expression
sentences.id: IEPA.d34.s85.e0
sentences.origID: 863
sentences.text: UCP
sentences.id: IEPA.d34.s85.e1
sentences.origID: 864
sentences.text: leptin