text:  PD03_3 2i-adapted mouse embryonic stem cells, PD0325901(1 μM), CHIR99021 and LIF are withdrawn for 24 hours treatment: PD0325901; cell line: 2i-adapated Ctnnb1-Biotin-3xFLAG knock-in ESC line (Ctnnb1-BioFLneo;BirA ESC)