tokens: T-lymphocyte proliferation is suppressed by 1 , 25-dihydroxyvitamin D3 [ 1 , 25 ( OH ) 2D3 ] , the active metabolite of vitamin D3 , and is associated with a decrease in interleukin 2 ( IL-2 ) , gamma interferon , and granulocyte-macrophage colony-stimulating factor mRNA levels .