tokens: PRAD1 , previously designated D11S287E , was identified on 11q13 as a chromosomal breakpoint region rearranged with the parathyroid hormone gene in a subset of parathyroid adenomas ; this highly conserved putative oncogene , which encodes a novel cyclin , has been linked to BCL1 and implicated also in subsets of breast and squamous cell neoplasms with 11q13 amplification .