tokens: This demonstrated ( 1 ) the association between mutations in exons 8 and 9 and DMS ; ( 2 ) among patients with DMS , a higher frequency of exon 8 mutations among 46 , XY patients with female phenotype than among 46 , XY patients with sexual ambiguity or male phenotype ; and ( 3 ) statistically significant evidence that mutations in exons 8 and 9 preferentially affect amino acids with different functions . .