tokens: Analysis was performed on 61 women with chemotherapy - responsive metastatic breast cancer receiving 96 - h infusional cyclophosphamide as part of a triple sequential high - dose regimen to assess association between presence of peritransplant congestive heart failure ( CHF ) and the following pretreatment characteristics : presence of electrocardiogram ( EKG ) abnormalities , age , hypertension , prior cardiac history , smoking , diabetes mellitus , prior use of anthracyclines , and left - sided chest irradiation .