tokens: METHODS : For a period of 2 weeks , CsA 15 mg / kg / day ( given orally ) , FK506 3 . 0 mg / kg / day ( given orally ) or SRL 0 . 4 mg / kg / day ( given intraperitoneally ) was administered once a day as these doses have earlier been found to achieve a significant immunosuppressive effect in Sprague - Dawley rats .