tokens: All six patients had supersaturated bile ( mean ( SEM ) cholesterol saturation index of 1 . 19 ( 0 . 08 ) ( range 1 . 01 - 1 . 53 ) ) and all had abnormally rapid cholesterol microcrystal nucleation times ( < 4 days ( range 1 - 4 ) ) , whilst in four , the bile contained cholesterol microcrystals immediately after sampling .