tokens: The herpesvirus entry mediator C ( HveC ) , previously known as poliovirus receptor - related protein 1 ( PRR1 ) , and the herpesvirus Ig - like receptor ( HIgR ) are the bona fide receptors employed by herpes simplex virus - 1 and - 2 ( HSV - 1 and - 2 ) for entry into the human cell lines most frequently used in HSV studies .