tokens: From 1977 to 1985 , 42 patients with squamous cell carcinoma of the anal canal were treated with mitomycin C ( 15 mg / m2 ) and 5 - fluorouracil ( 750 mg / m2 ) on day 1 , 5 - FU ( 750 mg / m2 / d ) alone on days 2 to 5 , and radiation therapy ( 3000 cGy ) on days 7 to 28 .