tokens: Lumbar spine bone mineral density ( BMD ) by dual - energy X - ray absorptiometry ( DXA ) increased by 0 . 6 % , 3 . 6 % and 8 . 1 % after 48 weeks in groups L , M and H respectively , responses in groups M and H being significantly higher than in L ( p < 0 . 05 , Mann - Whitney U - test ) .