passages.id: 1.0alpha7.train.1301.sent
passages.type: sentence
passages.text: The binding of  cyclin A to  CDC2 (sometimes referred to as  CDK1) or  CDK2 is a  pre-requisite for kinase activity and promotes phosphorylation on Thr161 or Thr160 (for  CDC2 or  CDK2, respectively), by the  CDK-activating kinase (CAK)      [17-21]  .
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