passages.id: 1.0alpha7.train.157.sent
passages.type: sentence
passages.text: Second, it is now believed that p27KIP1 interacts mostly with D-type cyclins and CDK4 and more weakly with cyclin E and CDK2, and that binding of p27KIP1 to cyclin D-CDK4 would allow the activation of cyclin E-CDK2 complexes at the G1-S transition (54, 55, 56).
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