passages.id: 1.0alpha7.train.1008.sent
passages.type: sentence
passages.text: However, when the upstream  AG is mutated, eliminating the binding of  SPF45 to the  pre-mRNA,  SXL still binds to the RNA, but is no longer able to inhibit the second step of splicing.
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coreferences.id: 1.0alpha7.train.1008.coref2
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