passages.id: 1.0alpha7.train.263.sent
passages.type: sentence
passages.text: This indicates that the binding of GSK-3beta to Axin is essential for its activity to degrade beta-catenin, consistent with the observation that AxindeltaGSK-3beta does not enhance the phosphorylation of beta-catenin even in the presence of APC-(1211-2075).
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