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passages.type: sentence
passages.text: We have previously shown that two E-boxes in the SM α-actin promoter at -214 bp (E1) and -252 bp (E2) functioned as positive regulatory elements in cultured SMCs and that USF proteins, ubiquitously expressed bHLH-leucine zipper transcription factors, activated the SM α-actin promoter in an E1-dependent (but not E2-dependent) manner.
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