passages.id: 1.0alpha7.train.269.sent
passages.type: sentence
passages.text: In this report, we show that AlF-C1 and AlF-C2 bind directly to Orc1, a subunit of ORC, and discuss that in mammalian cells, sequence-specific DNA-binding proteins might be involved in recruiting ORC to regulate replication initiation and/or transcription repression.
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