abstract: An apparently new syndrome of @entity231 , @entity1274 , @entity70801 , @entity851 , and @entity1032 was described by Gripp et al. 1996. The authors reported on two unrelated @entity1 with @entity231 , @entity1274 , distinctive facial appearance, @entity1032 , postnatal @entity851 , and skeletal changes. We report on two additional @entity1 with findings most similar to the reported @entity1 by Gripp et al. 1996, including bilateral @entity231 , @entity393 , @entity2122 , @entity851 , @entity853 , and @entity245 . Both of the @entity1 reported herein had chromosome microarray analysis, which showed normal results in @entity1 2 but abnormal results in @entity1 1 and his mother who both had a chromosome 11q25 subtelomere deletion. @entity1 1 and his mother's findings are atypical for the common findings reported in @entity19634 (11q terminal deletion syndrome), and consistent with the @entity1 reported by Gripp et al. 1996. The etiology for these cases has been unknown. The microarray results on @entity1 1 suggest that the other @entity1 with findings of @entity245 , @entity851 , @entity231 , @entity1274 , and similar craniofacial features may have either a microdeletion of chromosome 11q terminal region or haploinsufficiency of a gene localized to this region.
  
entities_list.pseudoidentifier: @entity1 @entity2122 @entity1032 @entity851 @entity231 @entity853 @entity245 @entity70801 @entity1274 @entity19634 @entity393
entities_list.identifier: ('9606', 'Species') ('MESH:D019465', 'Disease') ('MESH:D008607', 'Disease') ('MESH:D006130', 'Disease') ('MESH:D002386', 'Disease') ('MESH:D009139', 'Disease') ('MESH:D002658', 'Disease') ('MESH:C563390', 'Disease') ('MESH:D006319', 'Disease') ('MESH:D054868', 'Disease') ('MESH:D034381', 'Disease')
entities_list.synonyms: ['patients', 'Patient'] ['craniofacial abnormalities'] ['mental retardation'] ['short stature'] ['congenital cataracts'] ['skeletal abnormalities'] ['developmental delay'] ['Down syndrome-like facial appearance'] ['sensorineural hearing loss', 'sensorineural deafness'] ['Jacobsen syndrome'] ['hearing loss']