text: SUMMARY
  Both the innate and adaptive immune subsystems are necessary to provide an effective immune response whether to an actual pathogenic agent or to an immunization. Further, effective immunizations must induce long-term stimulation of both the humoral and cell-mediated arms of the adaptive system by the production of effector cells for the current infection and memory cells for future infections with the pathogenic agent. At least seven different types of vaccines are currently in use or in development that produce this effective immunity and have contributed greatly to the prevention of infectious disease around the world.
  
entities.text: ['immune subsystems']
entities.type: Anatomical_system
entities.entity_id: PMC-3068582-sec-06_T1
entities.text: ['cell']
entities.type: Cell
entities.entity_id: PMC-3068582-sec-06_T2
entities.text: ['effector cells']
entities.type: Cell
entities.entity_id: PMC-3068582-sec-06_T3
entities.text: ['memory cells']
entities.type: Cell
entities.entity_id: PMC-3068582-sec-06_T4