Four trials that were not combined in meta-analyses suggested that extracts with high ( > 30 mg/d ) levels of genistein consistently reduced the frequency of hot flushes .
BACKGROUND Vasomotor symptoms , such as hot flushes and night sweats , are very common during the menopausal transition .
Hormone therapy has traditionally been used as a highly effective treatment , but concerns about increased risk of some chronic diseases have markedly increased the interest of women in alternative treatments .
Some of the most popular of these treatments are foods or supplements enriched with phytoestrogens-plant-derived chemicals that have estrogenic action .
OBJECTIVES To assess the efficacy , safety and acceptability of food products , extracts and dietary supplements containing high levels of phytoestrogens when compared with no treatment , placebo or hormone therapy for the amelioration of vasomotor menopausal symptoms ( such as hot flushes and night sweats ) in perimenopausal and postmenopausal women .
Oestrogenic effects of plant foods in postmenopausal women.
Otolaryngol Head Neck Surg 1988;114 : 887 - 90 . 9 Jacobson JT , Morehouse CR . A comparison of auditory brain stem response  and behavioural screening in high risk and normal newborn infants . Ear Hear 1984;5:247 - 53 . 10 Mahoney TM , Eichwald JG . The ups and " downs " of high risk screening : the Utah statewide program . Seminars in Hearing 1987;8:155 - 63 . 11 Stein L , Clark S , Kraus N. The hearing impaired infant : patterns of identification and habilitation . Ear Hear 1983;4:232 - 6 . 12 Elssmann SF , Matkin ND , Sabo MP . Early identification of sensorineural hearing impairment . The HearingJournal 1987;40:13 - 7 . 13 American Speech-Hearing- Language Association . Guidelines for the identification of hearing impairment in at risk infants age birth to 6 months . ASHA 1988;30:61 - 4 . 14 Hendricks-Munoz KD , Walton JP .  Hearing loss in infants with persistent fetal circulation . Pediatrics 1988;81:650 - 6 . 15 Naulty CM , Weiss IP , Herer GR . Progressive sensorineural hearing loss in survivors of persistent fetal circulation . Ear Hear 1986;7:74 - 7 . 16 Hall DMB , ed . Screening for hearing impairment . In : Health for all children . Oxford : Oxford Medical Publications , 1989:59 - 67
Four trials that were not combined in meta-analyses suggested that extracts with high ( > 30 mg/d ) levels of genistein consistently reduced the frequency of hot flushes .
BACKGROUND Vasomotor symptoms , such as hot flushes and night sweats , are very common during the menopausal transition .
Hormone therapy has traditionally been used as a highly effective treatment , but concerns about increased risk of some chronic diseases have markedly increased the interest of women in alternative treatments .
Some of the most popular of these treatments are foods or supplements enriched with phytoestrogens-plant-derived chemicals that have estrogenic action .
OBJECTIVES To assess the efficacy , safety and acceptability of food products , extracts and dietary supplements containing high levels of phytoestrogens when compared with no treatment , placebo or hormone therapy for the amelioration of vasomotor menopausal symptoms ( such as hot flushes and night sweats ) in perimenopausal and postmenopausal women .