RESULTS No statistical significant difference in bond strength between both categories was observed in caries-affected dentin at immediate evaluation and in sound dentin after ageing .
Etch- and -rinse adhesives , however , performed better in sound enamel and dentin substrates considering immediate bond strength .
None study assessed the long-term adhesive effectiveness to sound or demineralized enamel .
Although the articles included in this meta- analysis showed high heterogeneity and high risk of bias , the in vitro literature suggests superior performance of etch- and -rinse adhesives in primary teeth in comparison with self-etch systems
AIM To systematic ally review the literature for in vitro studies that evaluated the immediate or after ageing bond strength of  etch- and -rinse and self-etch adhesive systems to enamel and dentin of primary teeth .
Casein Phosphopeptide-Amorphous Calcium Phosphate and Shear Bond Strength of Adhesives to Primary Teeth Enamel
Background : CPP-ACP ( Phosphopeptide-Amorphous Calcium Phosphate ) has an important role in caries prevention in pediatric patients . This study was done , because of the great use of CPP-ACP and the need for restoration for teeth treated with CPP-ACP as well as the importance of shear bond strength of adhesives in the success of restorations . Objectives : This study aim ed to evaluate the effect of casein phosphopeptide-amorphous calcium phosphate ( CPP-ACP ) on shear bond strength of dental adhesives to enamel of primary teeth molars . Material s and Methods : This in vitro study was conducted on 180 extracted primary molars . They were r and omly divided into 6 groups and each group was divided into 2 subgroups ( treated with CPP-ACP and untreated ) . In subgroups with CPP-ACP , enamel was treated with CPP-ACP paste 1 h/d for 5 days . Types of adhesives that were evaluated in this study were Tetric N-Bond , AdheSE , AdheSE One F , single Bond 2 , SE Bond , and Adper Prompt L-Pop . Shear bond strength was tested with a universal testing machine and mode of failure was evaluated under stereomicroscope . Data were analyzed by T test , 2-way analysis of variance ( ANOVA ) , Tukey and Fisher exact test using SPSS18 . P < 0.05 was considered as significance level . Results : Shear bond strengths of different adhesive systems to enamel of primary teeth treated and untreated with CPP-ACP showed no significant difference ( P > 0.05 ) . Mode of failure in all groups regardless of CPP-ACP administration was mainly adhesive type . Our results indicated that CPP-ACP did not affect shear bond strength of studied adhesives to primary teeth enamel . Conclusions : To have a successful and durable composite restoration , having a high strength bonding is essential . Considering the wide use of CPP-ACP in preventing tooth decay and the role of adhesive shear bond strength ( SBS ) in success of composite restoration , we conducted the present study to evaluate the effect of CPP-ACP on the SBS of adhesives to primary teeth enamel
RESULTS No statistical significant difference in bond strength between both categories was observed in caries-affected dentin at immediate evaluation and in sound dentin after ageing .
Etch- and -rinse adhesives , however , performed better in sound enamel and dentin substrates considering immediate bond strength .
None study assessed the long-term adhesive effectiveness to sound or demineralized enamel .
Although the articles included in this meta- analysis showed high heterogeneity and high risk of bias , the in vitro literature suggests superior performance of etch- and -rinse adhesives in primary teeth in comparison with self-etch systems
AIM To systematic ally review the literature for in vitro studies that evaluated the immediate or after ageing bond strength of  etch- and -rinse and self-etch adhesive systems to enamel and dentin of primary teeth .