The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .
Effects of lutein supplement on serum inflammatory cytokines, ApoE and lipid profiles in early atherosclerosis population.
AIM The purpose of this study was to determine the effects of lutein supplement on serum cytokines , apoE and lipoprotein profiles in early atherosclerosis population . METHODS Early atherosclerosis patients ( n= 65 ) were r and omized to receive placebo ( A+P , n= 31 ) or 20 mg/d lutein ( A+L , n= 34 ) for 3 months . RESULTS Serum lutein increased significantly compared to baseline after lutein supplements in A+L group ( p<0.001 ) . Lutein supplements result ed in a significant decrease in serum interleukin-6 ( IL-6 ) and monocyte chemoattractant protein-1 ( MCP-1 ) at 3 month in A+L group ( p<0.05 ) . Intragroup comparison revealed a significant difference in the changes of serum MCP-1 between A+L and A+P groups ( p= 0.021 ) . The serum low-density lipoprotein ( LDL ) and triglyceride ( TG ) significantly decreased in A+L group ( p<0.05 ) . The changes in serum lutein were negatively associated with those in serum LDL in A+L group ( r=-0.384 , p=0.043 ) , while no such relationship was observed in A+P group ( r= 0.087 , p= 0.685 ) . CONCLUSION An increase in serum lutein after supplementation can reduce inflammatory cytokines and regulate serum lipids , which may pay important roles in early atherosclerosis
The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .