There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Fish oil-supplementation from 9 to 12 months of age affects infant attention in a free-play test and is related to change in blood pressure.
INTRODUCTION This intervention examined whether fish-oil-supplementation in late infancy modifies free-play test scores and if this is related to blood pressure ( BP ) and mean RR interval . PATIENTS AND METHODS 83 Danish 9-month-old infants were r and omized to ±fish oil ( FO ) ( 3.4±1.1mL/d ) for 3months and 61 of these completed the free-play-test before and after the intervention . RESULTS Most of the free-play scores changed during the intervention , but the intervention affected only the number of looks away from the toy , which was increased in + FO and decreased in -FO ( p=0.037 ) . The increased numbers of looks away were associated with an increase in erythrocyte eicosapentaenoic acid ( r=0.401 , p=0.017 , n=35 ) and were also associated with a decrease in systolic-BP ( r=-0.511 , p<0.001 , n=52 ) . CONCLUSIONS The results indicate that n-3 fatty acid intake also in late infancy can influence brain development and that the cognitive and cardiovascular effects may be related
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .