Evidence suggests that pragmatic diabetes prevention programs are effective .
Effectiveness varies substantially between programs but can be improved by maximizing guideline adherence .
OBJECTIVE To summarize the evidence on effectiveness of translational diabetes prevention programs , based on promoting lifestyle change to prevent type 2 diabetes in real-world setting s and to examine whether adherence to international guideline recommendations is associated with effectiveness .
Lifestyle interventions aim ed to translate evidence from previous efficacy trials of diabetes prevention into real-world intervention programs .
The Pre-diabetes Risk Education and Physical Activity Recommendation and Encouragement (PREPARE) programme study: are improvements in glucose regulation sustained at 2 years?
OBJECTIVE To determine whether improvements in glucose regulation following the PREPARE structured education programme were sustained at 24 months . PATIENTS AND METHODS Ninety-eight overweight or obese individuals with impaired glucose tolerance were r and omized to receive : ( 1 ) advice leaflet , ( 2 ) 3-h structured education programme aim ed at promoting physical activity , ( iii ) 3-h structured education with personalized pedometer use . The primary outcome was change in 2-h post-challenge plasma glucose . RESULTS Seventy-three ( 74 % ) individuals were included for analysis at 24 months ; age 65 ± 8 years , BMI 29.3 ± 4.8 kg/m(2 ) , South Asian ethnicity 21 % . A statistically significant reduction in 2-h glucose of -1.6 mmol/l ( -0.4 to -2.7 ) was seen in the education-with-pedometer group compared with the control group . There is no significant difference in the education-only group . CONCLUSION Improvements in glucose regulation following a pragmatic group-based structured education with pedometer use were sustained at 24 months
Evidence suggests that pragmatic diabetes prevention programs are effective .
Effectiveness varies substantially between programs but can be improved by maximizing guideline adherence .
OBJECTIVE To summarize the evidence on effectiveness of translational diabetes prevention programs , based on promoting lifestyle change to prevent type 2 diabetes in real-world setting s and to examine whether adherence to international guideline recommendations is associated with effectiveness .
Lifestyle interventions aim ed to translate evidence from previous efficacy trials of diabetes prevention into real-world intervention programs .