Significant heterogeneity was not observed by nut type or other factors .
Tree nut intake  lowers total cholesterol , LDL cholesterol , ApoB , and triglycerides .
The major determinant of cholesterol lowering appears to be nut dose rather than nut type .
BACKGROUND The effects of nuts on major cardiovascular disease ( CVD ) risk factors , including dose-responses and potential heterogeneity by nut type or phytosterol content , are not well established .
OBJECTIVES We examined the effects of tree nuts ( walnuts , pistachios , macadamia nuts , pecans , cashews , almonds , hazelnuts , and Brazil nuts ) on blood lipids [ total cholesterol , low-density lipoprotein ( LDL ) cholesterol , high-density lipoprotein , and triglycerides ] , lipoproteins [ apolipoprotein A1 , apolipoprotein B ( ApoB ) , and apolipoprotein B100 ] , blood pressure , and inflammation ( C-reactive protein ) in adults aged ≥18 y without prevalent CVD .
A Pilot Study on the Effects of Almond Consumption on DNA Damage and Oxidative Stress in Smokers
Abstract : The effects of almond consumption on DNA damage and oxidative stress among cigarette smokers were studied . Thirty healthy adult male regular smokers were r and omly divided into three groups , 10 subjects per group . Group A ( control group ) did not receive any almonds . Subjects in Groups B and C received 3 oz and 6 oz ( 84 g and 168 g ) of almonds each day respectively for 4 wk . Two known biomarkers for DNA damage , urinary 8-hydroxy-2’-deoxyguanosine ( 8-OH-dG ) and single str and DNA breaks of peripheral blood lymphocytes , were measured by enzyme-linked immunosorbent assay and comet assay , respectively . In addition , plasma malondialdehyde ( MDA ) level , superoxide dismutase ( SOD ) , and glutathione peroxidase ( GSH-Px ) activities were measured as biomarkers for oxidative stress . The results showed lower levels of urinary 8-OH-dG and single str and DNA breaks in the two almond-treated groups as compared with the control group . Furthermore , MDA levels in the almond-treated groups were lower than the controls . However , no significant effects of almonds  on SOD and GSH-Px activities were found . In conclusion , results from this pilot study indicate that almond consumption has preventive effects on oxidative stress and DNA damage caused by smoking . A larger , r and omized , placebo-controlled clinical trial on almonds will be initiated in the near future
Significant heterogeneity was not observed by nut type or other factors .
Tree nut intake  lowers total cholesterol , LDL cholesterol , ApoB , and triglycerides .
The major determinant of cholesterol lowering appears to be nut dose rather than nut type .
BACKGROUND The effects of nuts on major cardiovascular disease ( CVD ) risk factors , including dose-responses and potential heterogeneity by nut type or phytosterol content , are not well established .
OBJECTIVES We examined the effects of tree nuts ( walnuts , pistachios , macadamia nuts , pecans , cashews , almonds , hazelnuts , and Brazil nuts ) on blood lipids [ total cholesterol , low-density lipoprotein ( LDL ) cholesterol , high-density lipoprotein , and triglycerides ] , lipoproteins [ apolipoprotein A1 , apolipoprotein B ( ApoB ) , and apolipoprotein B100 ] , blood pressure , and inflammation ( C-reactive protein ) in adults aged ≥18 y without prevalent CVD .