This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .
Comparison of 40 milliliters of 0.25% intrapleural bupivacaine with epinephrine with 20 milliliters of 0.5% intrapleural bupivacaine with epinephrine after cholecystectomy.
To determine the influence of the volume of local anesthetic injected for intrapleural analgesia , 40 patients undergoing cholecystectomy were r and omly allocated to two groups of 20 patients each . One group received 40 mL of 0.25 % bupivacaine with epinephrine injected intrapleurally postoperatively . The other group received 20 mL of 0.5 % bupivacaine with epinephrine . The onset time of analgesia was nearly the same in both groups and within 25 min all patients were nearly pain free . Our data demonstrate that 100 mg of bupivacaine with epinephrine elicits effective analgesia after cholecystectomy . There are only minor differences between 20 and 40 mL with regard to pain relief . The authors conclude that the volume of local anesthetic within the range of 20 - 40 mL in an adult has little influence on the extent or duration of intrapleural analgesia
This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .