Conclusion l-carnitine consumption does not reduce serum leptin significantly .
However , a significant effect on leptin was observed in diabetic patients and patients who received doses more than 3 mg per day in the course of < 12 weeks
Purpose The actual effects of l-carnitine administration on leptin serum level is inconsistent .
In order to assess the efficacy of l-carnitine supplementation on serum leptin we conducted a meta- analysis of r and omized controlled trials ( RCTs ) .
Safety Measures of L‐Carnitine L‐Tartrate Supplementation in Healthy Men
The purpose of this investigation was to examine the effects of ingestion of L-CARNIPURE ( L-carnitine L-tartrate [ LCLT ] ) on alterations in a complete blood cell profile and in circulating metabolic enzymes . Using a balanced , placebo ( P ) , cross-over design ( 1 week washout ) , 10 healthy , active men volunteered and acted as their own control taking either a  P or LCLT supplement ( 3 gday−1 ) for 3 weeks  . Postabsorptive morning blood sample s were obtained both before and after 21 days of P and LCLT supplementation . Serum sample s were analyzed for clinical chemistries including a complete chemistry panel with markers of liver and renal function along with various minerals and electrolytes . In addition , whole blood was analyzed for a complete blood count with differential . It was determined that there were no statistically significant differences between the LCLT and the placebo conditions for any of the variables examined . The results of this study suggest that LCLT , when used as a dietary supplement , has no adverse effects on metabolic and hemato-logical safety variables in normally healthy en
Conclusion l-carnitine consumption does not reduce serum leptin significantly .
However , a significant effect on leptin was observed in diabetic patients and patients who received doses more than 3 mg per day in the course of < 12 weeks
Purpose The actual effects of l-carnitine administration on leptin serum level is inconsistent .
In order to assess the efficacy of l-carnitine supplementation on serum leptin we conducted a meta- analysis of r and omized controlled trials ( RCTs ) .