Similar effects also appeared in SBP and DBP categories regardless of follow-up duration .
PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions .
In adults without IGT or diabetes , lifestyle interventions result ed in significant improvements in SBP , DBP , TC , LDL-C , HDL-C , and TG , and might further reduce CVD risk
Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease ( CVD ) risk among persons with impaired glucose tolerance ( IGT ) , but it is unclear whether they should be implemented among persons without IGT .
We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes .
One-year effectiveness of two hypocaloric diets with different protein/carbohydrate ratios in weight loss and insulin resistance.
BACKGROUND The maintenance of weight loss may be influenced by the distribution of macronutrients in the diet and insulin sensitivity . OBJECTIVE The objective of the study was to evaluate the longterm effect of two hypocaloric diets with different protein/carbohydrate ratios in overweight and obese individuals either with insulin resistance ( IR ) or without insulin resistance ( IS ) . DESIGN Prospect i ve , r and omized , clinical intervention study . Forty patients were classified as IR/IS after a 75 g oral glucose tolerance test and then r and omized to a diet with either 40 % carbohydrate/30 % protein/30 % fat ( diet A ) or 55 % carbohydrate/15 % protein/30 % fat ( diet B ) . RESULTS After one year of follow-up there was no difference in weight loss between diets A and B in each group , but the IS group maintained weight loss better than the IR group [ -5.7 ( 3.9 ) vs. -0.6 ( 4.1 ) ; P = 0.04 ] . No differences were found in either Homeostasis Model Assessment ( HOMA ) or other metabolic glucose parameters except lower insulin at 120 minutes with diet A [ 21.40 ( 8.30 ) vs. 71.40 ( 17.11 ) ; P = 0.02 ] . CONCLUSIONS The hypocaloric diets with different protein/carbohydrate ratios produced similar changes in weight . Insulin resistance may play a negative role in maintaining weight loss
Similar effects also appeared in SBP and DBP categories regardless of follow-up duration .
PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions .
In adults without IGT or diabetes , lifestyle interventions result ed in significant improvements in SBP , DBP , TC , LDL-C , HDL-C , and TG , and might further reduce CVD risk
Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease ( CVD ) risk among persons with impaired glucose tolerance ( IGT ) , but it is unclear whether they should be implemented among persons without IGT .
We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes .