Conclusion Our findings may encourage curcumin supplementation based on its meaningful effect on glycemic control and positive trend on lipid outcomes in prediabetes and T2DM
Scope Studies have demonstrated inconsistent effects of curcumin on glycemic outcomes and lipid parameters in patients with prediabetes and type 2 diabetes mellitus ( T2DM ) .
This study aim ed to assess the effect of curcumin on glycemic control and lipid profile in prediabetes and T2DM .
Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial.
Curcumin is a phytocompound found in the root of turmeric , a common herbal ingredient in many Asian cuisines . The compound contains anti-inflammatory activity , which is mediated through an up-regulation of adiponectin and reduction of leptin . Consumption of curcumin was shown to prevent some deteriorative conditions caused by inflammation , such as ulcerative colitis , rheumatoid arthritis and esophagitis , and so on . Inflammation-associated cardiovascular conditions such as atherosclerosis are common in diabetes patients . The anti-inflammation effect of curcumin might be beneficial to prevent such condition in these patients . We aim to evaluate an antiatherosclerosis effect of curcumin in diabetes patients . Effects of curcumin on risk factors for atherosclerosis were investigated in a 6-month r and omized , double-blinded and placebo-controlled clinical trial that included subjects diagnosed with type 2 diabetes . An atherosclerosis parameter , the pulse wave velocity , and other metabolic parameters in patients treated with placebo and curcumin were compared . Our results showed that curcumin intervention significantly reduced pulse wave velocity , increased level of serum adiponectin and decreased level of leptin . These results are associated with reduced levels of homeostasis model assessment -insulin resistance , triglyceride , uric acid , visceral fat and total body fat . In summary , a 6-month  curcumin  intervention in type 2 diabetic population lowered the atherogenic risks . In addition , the extract helped to improve relevant metabolic profiles in this high-risk population
Conclusion Our findings may encourage curcumin supplementation based on its meaningful effect on glycemic control and positive trend on lipid outcomes in prediabetes and T2DM
Scope Studies have demonstrated inconsistent effects of curcumin on glycemic outcomes and lipid parameters in patients with prediabetes and type 2 diabetes mellitus ( T2DM ) .
This study aim ed to assess the effect of curcumin on glycemic control and lipid profile in prediabetes and T2DM .