For most comparisons , the credibility of evidence was rated very low to moderate , with the exception for the DASH vs. the low-fat dietary approach for which the quality of evidence was rated high .
Conclusion : The present network meta- analysis suggests that the DASH dietary approach might be the most effective dietary measure to reduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
ABSTRACT Background : Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood pressure but their comparative effects have not been established .
Objective : Therefore we performed a systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects through network meta- analysis including hypertensive and pre-hypertensive patients .
Assessment of quality of life in a randomized clinical trial of candesartan only or in combination with DASH diet for hypertensive patients.
OBJECTIVES A r and omized clinical trial was used to compare the effects of an angiotensin II type 1 receptor inhibitor , c and esartan , singly or in combination with a reducing sodium diet , the DASH diet , on the quality of life ( QOL ) in out patients with hypertension . METHODS After a 2-week wash out period with placebo , 102 patients with mild to moderate hypertension were r and omly assigned to receive c and esartan ( 8 to 16 mg per day ) , and 99 patients were assigned to follow the DASH diet in addition to the same dose of c and esartan , both for 16 weeks . Patients completed the Subjective Symptoms Assessment Profile question naire , just before treatment and at the end of treatment . ANOVA was used to analyze the QOL-score changes over time and compare treatments . RESULTS Resting blood pressures were significantly reduced by the combination of c and esartan and DASH diet ( p < 0.005 ) . Significant improvement was demonstrated for the mental component scores after 16 weeks of treatment with the combination of c and esartan and DASH diet ( p < 0.03 ) . CONCLUSIONS Angiotensin II type 1 receptor blockade with a therapeutic dosage of c and esartan maintains significant control of blood pressure and may improve QOL-scores , especially when combined with a reducing sodium diet
For most comparisons , the credibility of evidence was rated very low to moderate , with the exception for the DASH vs. the low-fat dietary approach for which the quality of evidence was rated high .
Conclusion : The present network meta- analysis suggests that the DASH dietary approach might be the most effective dietary measure to reduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
ABSTRACT Background : Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood pressure but their comparative effects have not been established .
Objective : Therefore we performed a systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects through network meta- analysis including hypertensive and pre-hypertensive patients .