Only antibiotic-impregnated suture , a no-shave policy , and double gloving with glove change prior to shunt h and ling , were associated with a significant reduction in shunt infection .
In a hospital with high methicillin-resistant staphylococcus aureus ( MRSA ) prevalence , a r and omized controlled trial found that perioperative vancomycin rather than cefazolin significantly reduced shunt infection rates .
Conclusion Despite wide variation in compliance rates , the implementation of comprehensive surgical protocol s reduced shunt infection in all published studies .
Antibiotic-impregnated suture , a no-shave policy , double gloving with glove change prior to device manipulation , and 5 % chlorhexidine hair wash were associated with significant reductions in shunt infection
Purpose Cerebrospinal fluid shunt infection is associated with patient morbidity and high cost .
We conducted a systematic review of the current evidence of comprehensive surgical protocol s or individual interventions design ed to reduce shunt infection incidence .
A randomised control trial on the use of topical methicillin in reducing post-operative ventriculoperitoneal shunt infection.
BACKGROUND A double-blind r and omised control study was conducted on all patients who were admitted or referred to the Department of Neurosurgery , Sultanah Aminah Hospital , Johor Bahru , with a diagnosis of hydrocephalus where a ventriculoperitoneal shunt was indicated . METHODS The period of study was from November 2005 to May 2007 , and the follow-up period was 3 months after surgery . R and omisation was carried out in the operating room prior to the procedure . The scrub nurse selected a sealed envelope , which contained the assignment of each patient to 1 of 2 treatment groups : Group 1 patients were treated with topical methicillin , and Group 2 patients were not treated with topical methicillin . Prophylactic antibiotic , cefuroxime ( 25 mg/kg ) was given intravenously at induction . St and ard sterile operative technique was followed in preparing and draping the patients . RESULTS A total of 90 patients were recruited in the study , and 13 ( 14.4 % ) patients developed an infection within 3 months post-operation . Group 1 had a 8.9 % risk of infection , and Group 2 had a 20 % risk ; however , there was no statistically significant post-operative ventriculoperitoneal shunt ( VPS ) infection reduction with the use of topical methicillin in VPS surgery ( P = 0.230 ) . Multivariate analysis showed that only duration of surgery had a significant influence on the incidence of post-operative VPS infection in the non-methicillin group ( P = 0.02 ) . The non-methicillin group had an 8 times greater risk of developing post-operative VPS infection than the methicillin group if surgery lasted longer than 1 hour . CONCLUSION Topical methicillin had no significance in the reduction of post-operative VPS infection
Only antibiotic-impregnated suture , a no-shave policy , and double gloving with glove change prior to shunt h and ling , were associated with a significant reduction in shunt infection .
In a hospital with high methicillin-resistant staphylococcus aureus ( MRSA ) prevalence , a r and omized controlled trial found that perioperative vancomycin rather than cefazolin significantly reduced shunt infection rates .
Conclusion Despite wide variation in compliance rates , the implementation of comprehensive surgical protocol s reduced shunt infection in all published studies .
Antibiotic-impregnated suture , a no-shave policy , double gloving with glove change prior to device manipulation , and 5 % chlorhexidine hair wash were associated with significant reductions in shunt infection
Purpose Cerebrospinal fluid shunt infection is associated with patient morbidity and high cost .
We conducted a systematic review of the current evidence of comprehensive surgical protocol s or individual interventions design ed to reduce shunt infection incidence .