Surgery results in greater improvement in weight loss outcomes and weight associated comorbidities compared with non-surgical interventions , regardless of the type of procedures used .
When compared with each other , certain procedures result ed in greater weight loss and improvements in comorbidities than others .
Outcomes were similar between RYGB and sleeve gastrectomy , and both of these procedures had better outcomes than adjustable gastric b and ing .
For people with very high BMI , biliopancreatic diversion with duodenal switch result ed in greater weight loss than RYGB .
Isolated sleeve gastrectomy led to better weight-loss outcomes than adjustable gastric b and ing after three years follow-up .
BACKGROUND Bariatric ( weight loss ) surgery for obesity is considered when other treatments have failed .
The effects of the available bariatric procedures compared with medical management and with each other are uncertain .
This is an up date of a Cochrane review first published in 2003 and most recently up date d in 2009 .
OBJECTIVES To assess the effects of bariatric surgery for overweight and obesity , including the control of comorbidities .
Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial.
BACKGROUND Obesity is a risk factor for cancer . Intentional weight loss in the obese might protect against malignancy , but evidence is limited . To our knowledge , the Swedish Obese Subjects ( SOS ) study is the first intervention trial in the obese population to provide prospect i ve , controlled cancer-incidence data . METHODS The SOS study started in 1987 and involved 2010 obese patients ( body-mass index [ BMI ] > or=34 kg/m(2 ) in men , and > or=38 kg/m(2 ) in women ) who underwent bariatric surgery and 2037 contemporaneously matched obese controls , who received conventional treatment .  While the main endpoint of SOS was overall mortality , the main outcome of this exploratory report was cancer incidence until Dec 31 , 2005 . Cancer  follow-up rate was 99.9 % and the median follow-up time was 10.9 years ( range 0 - 18.1 years ) . FINDINGS Bariatric surgery result ed in a sustained mean weight reduction of 19.9 kg ( SD 15.6 kg ) over 10 years , whereas the mean weight change in controls was a gain of 1.3 kg ( SD 13.7 kg ) . The number of first-time cancers after inclusion was lower in the surgery group ( n=117 ) than in the control group ( n=169 ; HR 0.67 , 95 % CI 0.53 - 0.85 , p=0.0009 ) . The sex-treatment interaction p value was 0.054 . In women , the number of first-time cancers after inclusion was lower in the surgery group ( n=79 ) than in the control group ( n=130 ; HR 0.58 , 0.44 - 0.77 ; p=0.0001 ) , whereas there was no effect of surgery in men ( 38 in the surgery group vs 39 in the control group ; HR 0.97 , 0.62 - 1.52 ; p=0.90 ) . Similar results were obtained after exclusion of all cancer cases during the first 3 years of the intervention . INTERPRETATION Bariatric surgery was associated with reduced cancer incidence in obese women but not in obese men . FUNDING Swedish Research Council , Swedish Foundation for Strategic Research , Swedish Federal Government under the LUA/ALF agreement , Hoffmann La Roche , Cederoths , AstraZeneca , Sanofi-Aventis , Ethicon Endosurgery
Surgery results in greater improvement in weight loss outcomes and weight associated comorbidities compared with non-surgical interventions , regardless of the type of procedures used .
When compared with each other , certain procedures result ed in greater weight loss and improvements in comorbidities than others .
Outcomes were similar between RYGB and sleeve gastrectomy , and both of these procedures had better outcomes than adjustable gastric b and ing .
For people with very high BMI , biliopancreatic diversion with duodenal switch result ed in greater weight loss than RYGB .
Isolated sleeve gastrectomy led to better weight-loss outcomes than adjustable gastric b and ing after three years follow-up .
BACKGROUND Bariatric ( weight loss ) surgery for obesity is considered when other treatments have failed .
The effects of the available bariatric procedures compared with medical management and with each other are uncertain .
This is an up date of a Cochrane review first published in 2003 and most recently up date d in 2009 .
OBJECTIVES To assess the effects of bariatric surgery for overweight and obesity , including the control of comorbidities .