CLINICAL IMPLICATION S Only SCORAD , EASI , and POEM currently perform adequately .
BACKGROUND Valid and reliable outcome measurements are a prerequisite for evidence -based practice .
The comparative validity and reliability of outcome measurements for assessing atopic eczema ( AE ) severity is unclear .
OBJECTIVE We sought to assess the validity , reliability , sensitivity to change , and ease of use of outcome measurements for AE .
We also sought to give recommendations on which outcomes to use in clinical research and for clinical monitoring .
Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis
Treatment of atopic dermatitis with essential fatty acids remains controversial . A double-blind , placebo-controlled , parallel-group study was done to investigate the response of patients with atopic dermatitis to essential fatty acid supplements .  Patients with atopic dermatitis were r and omised to receive evening primrose oil , evening primrose oil and fish oil , or placebo for 16 weeks . Disease activity was monitored by clinical severity scores recorded by the investigator , topical steroid requirement , and symptom scores recorded by subjects . Of 123 subjects recruited , 102 completed the treatment period . No improvement with active treatment was demonstrated . Our study , which avoided the method ological and analytical problems of previous studies , found no effect of essential fatty acid supplementation in atopic dermatitis
CLINICAL IMPLICATION S Only SCORAD , EASI , and POEM currently perform adequately .
BACKGROUND Valid and reliable outcome measurements are a prerequisite for evidence -based practice .
The comparative validity and reliability of outcome measurements for assessing atopic eczema ( AE ) severity is unclear .
OBJECTIVE We sought to assess the validity , reliability , sensitivity to change , and ease of use of outcome measurements for AE .
We also sought to give recommendations on which outcomes to use in clinical research and for clinical monitoring .