When each device is compared incrementally , BioMonitor 2-AF dominates Reveal LINQ and Confirm RX .
BACKGROUND Cryptogenic stroke is a stroke for which no cause is identified after st and ard diagnostic tests .
Long-term implantable cardiac monitors may be better at diagnosing atrial fibrillation and provide an opportunity to reduce the risk of stroke recurrence with anticoagulants .
OBJECTIVES The objectives were to assess the diagnostic test accuracy , clinical effectiveness and cost-effectiveness of three implantable monitors [ BioMonitor 2-AF ™ ( Biotronik SE & Co. KG , Berlin , Germany ) , Confirm Rx ™ ( Abbott Laboratories , Lake Bluff , IL , USA ) and Reveal LINQ ™ ( Medtronic plc , Minneapolis , MN , USA ) ] in patients who have had a cryptogenic stroke and for whom no atrial fibrillation is detected after 24 hours of external electrocardiographic monitoring .
Valuation of EQ-5D health states in Poland: first TTO-based social value set in Central and Eastern Europe.
OBJECTIVE Currently , there is no EQ-5D value set for Pol and . The primary objective of this study was to elicit EQ-5D Polish values using the time trade-off ( TTO ) method . METHODS Face-to-face interviews with visitors of in patients in eight medical centers in Warsaw , Skierniewice , and Puławy were carried out by trained interviewers . Quota sampling was used to achieve a representative sample of the Polish population with regard to age and sex . Modified protocol from the Measurement and Value of Health study was used . Each respondent ranked 10 health states and valued 4 health states using the visual analog scale and 23 using the TTO . Mean and variance stability tests were performed to determine whether using a larger number of health states per respondent would yield credible results . Modeling included r and om effects and r and om parameters models . RESULTS Between February and May 2008 , 321 interviews were performed . Modeling based on 6777 valuations result ed in an additive model with all coefficients statistically significant , R(2 ) equal to 0.45 , and value -0.523 for the worst possible health state . Means and variance did not differ significantly for states valued in the middle and at the end of the TTO exercise . CONCLUSIONS This is the first EQ-5D value set based on TTO in Central and Eastern Europe so far . Because the values differ considerably from those elicited in Western European countries , its use should be recommended for studies in Pol and . Increasing the number of health states that each respondent is asked to value using TTO seems feasible and justifiable
When each device is compared incrementally , BioMonitor 2-AF dominates Reveal LINQ and Confirm RX .
BACKGROUND Cryptogenic stroke is a stroke for which no cause is identified after st and ard diagnostic tests .
Long-term implantable cardiac monitors may be better at diagnosing atrial fibrillation and provide an opportunity to reduce the risk of stroke recurrence with anticoagulants .
OBJECTIVES The objectives were to assess the diagnostic test accuracy , clinical effectiveness and cost-effectiveness of three implantable monitors [ BioMonitor 2-AF ™ ( Biotronik SE & Co. KG , Berlin , Germany ) , Confirm Rx ™ ( Abbott Laboratories , Lake Bluff , IL , USA ) and Reveal LINQ ™ ( Medtronic plc , Minneapolis , MN , USA ) ] in patients who have had a cryptogenic stroke and for whom no atrial fibrillation is detected after 24 hours of external electrocardiographic monitoring .