There were no overall effects from antioxidant vitamins , inositol or dietary minerals on psychiatric symptoms .
There is preliminary evidence that certain vitamin and mineral supplements may reduce psychiatric symptoms in some people with schizophrenia .
BACKGROUND When used as an adjunctive with antipsychotics , certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia , by restoring nutritional deficits , reducing oxidative stress , or modulating neurological pathways .
The effect of vitamin E addition to acute neuroleptic treatment on the emergence of extrapyramidal side effects in schizophrenic patients: An open label study
The anti-oxidant vitamin E has been reported to be effective in the treatment of tardive dyskinesia . The present open label study examined the effect of supplemental therapy with vitamin E on acute extrapyramidal symptoms and cell enzymes in patients receiving neuroleptic drugs . Thirty-nine hospitalized schizophrenic patients were r and omly assigned to two groups : group 1 ( n = 20 ) was treated with neuroleptics , and group 2 ( n = 19 ) with neuroleptics combined with a fixed dose of vitamin E ( 600 IU/day ) , administered for two weeks . All patients were assessed with the Simpson-Angus Rating Scale ( Simpson and Angus , 1970 ) for neuroleptic induced Parkinsonism ( NIP ) , Barnes ' Akathisia Scale ( Barnes , 1989 ) , and Brief Psychiatric Rating Scale : laboratory parameters included serum creatine kinase ( CK ) activity , serum glutamate oxaloacetic transaminase ( SGOT ) and white blood cell count ( WBC ) . The addition of vitamin E to neuroleptic agents was associated with a trend ( p = 0.08 ) towards prevention of the emergence of NIP compared to neuroleptic treatment alone . Addition of vitamin E to neuroleptics may reduce the severity of acute NIP in schizophrenic patients
There were no overall effects from antioxidant vitamins , inositol or dietary minerals on psychiatric symptoms .
There is preliminary evidence that certain vitamin and mineral supplements may reduce psychiatric symptoms in some people with schizophrenia .
BACKGROUND When used as an adjunctive with antipsychotics , certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia , by restoring nutritional deficits , reducing oxidative stress , or modulating neurological pathways .