The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .
Clinical effect of a new liquid dentifrice containing triclosan/copolymer on existing plaque and gingivitis.
BACKGROUND Dentifrices traditionally have been formulated as pastes or gels . However , liquid varieties recently have become available The authors conducted a study to determine whether a fluori date d liquid product with added triclosan and a polyvinyl methyl ether/maleic acid , or PVM/MA , copolymer delivery system is efficacious for the control of supragingival plaque and gingivitis . METHODS The authors conducted a six-month , double-blind , parallel , stratified clinical study in accordance with American Dental Association guidelines for the clinical evaluation of antiplaque/antigingivitis products . Subjects who qualified with a suitable amount of existing plaque and gingivitis were given one of two dentifrices : an " experimental " liquid dentifrice containing 0.3 percent triclosan , 2.0 percent PVM/MA copolymer and 0.243 percent sodium fluoride , or NaF , in a silica base ; or a " placebo " dentifrice containing 0.243 percent NaF in a silica base . The authors collected subjects ' plaque and gingival index scores at baseline , three months and six months . RESULTS The results of the study indicate that the use of the experimental liquid dentifrice provided a significant reduction in existing levels of plaque and gingivitis as compared with the placebo st and ard dentifrice . At six months , the experimental group demonstrated a 34.9 percent reduction in plaque formation and a 25.7 percent reduction in gingivitis as compared with the placebo group ( P < .001 ) . CONCLUSIONS When compared with the placebo , the experimental dentifrice had a significantly better ability to reduce plaque and gingivitis . When compared with results reported in the literature , this new form of dentifrice achieved results comparable in efficacy to those of traditional dentifrice pastes with matching active ingredients . CLINICAL IMPLICATION S This study confirms that a liquid dentifrice containing a triclosan/copolymer/NaF delivery system is efficacious in its ability to reduce existing plaque and gingivitis
The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .