The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .
Plasma carotenoids and risk of acute myocardial infarction in the Singapore Chinese Health Study.
BACKGROUND AND AIM Modification of low-density lipoprotein due to oxidative stress is essential in the development of coronary atherosclerosis . Data of specific carotenoids except β-carotene on cardioprotective effects in humans are limited . METHODS AND RESULTS This study examined the associations between plasma concentrations of specific carotenoids and incidence of acute myocardial infa rct ion . The study included 280 incident cases of acute myocardial infa rct ion and 560 matched controls nested within the Singapore Chinese Health Study , a prospect i ve cohort of 63,257 Chinese men and women aged 45 - 74 years old enrolled in 1993 - 1998 in Singapore . Retinol and carotenoids in prediagnostic plasma were quantified using high-performance liquid chromatography . High levels of plasma β-cryptoxanthin and lutein were associated with decreased risk of acute myocardial infa rct ion after adjustment for multiple risk factors for coronary heart disease . For β-cryptoxanthin , the odds ratio ( 95 % confidence interval ) for the highest ( Q5 ) versus the lowest ( Q1 ) quintile was 0.67 ( 0.37 - 1.21 ) ( P for trend=0.03 ) . For lutein , the odds ratios ( 95 % confidence intervals ) for the combined Q2-Q3 and the combined Q4-Q5 versus Q1 were 0.71 ( 0.45 - 1.12 ) and 0.58 ( 0.35 - 0.94 ) respectively ( P for trend=0.03 ) . There was no statistically significant association between other carotenoids or retinol and risk of acute myocardial infa rct ion . CONCLUSIONS High plasma levels of β-cryptoxanthin and lutein were associated with decreased risk of acute myocardial infa rct ion . The findings of this study support a cardioprotective role of these two carotenoids in humans
The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .