In the meta- analysis , tadalafil and sildenafil appeared to have similar efficacies and overall adverse event rates .
However , compared with sildenafil , tadalafil significantly improved psychological outcomes .
Furthermore , the patients and their partners preferred tadalafil over sildenafil , and no significant difference was found in the adherence and persistence rates between tadalafil and sildenafil .
Additionally , the myalgia and back pain rates were higher and the flushing rate was lower with tadalafil than with sildenafil .
Conclusion Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients ’ sexual confidence .
Furthermore , patients and their partners prefer tadalafil to sildenafil .
Hence , tadalafil may be a better choice for ED treatment
Aims Erectile dysfunction ( ED ) is a major care problem worldwide .
Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED .
This systematic review and meta- analysis were conducted to directly compare tadalafil with sildenafil for the treatment of ED .
Prevalence of erectile dysfunction and possible risk factors among men of South-Western Nigeria: a population based study
Introduction Erectile dysfunction ( ED ) is currently one of the most common sexual dysfunctions worldwide but it is usually underestimated because it is not a life threatening condition . The associated stigma makes men who have it to suffer in silence . This study was conducted to determine the prevalence of erectile dysfunction and the possible associated risk factors among Nigerian men . Methods The study was a descriptive cross-sectional population based survey  among men aged 30 - 80 years in Ogbomoso , South-west , Nigeria . A multistage r and om sampling method was used . The instrument used was the  International Index of Erectile Function Question naire-5 ( IIEF-5 ) . Unadjusted odds ratios of possible risk factors were calculated by univariate analyses . Binary logistic regression analysis was used to eliminate the effect of possible confounders on the risk factors to get the adjusted odds ratios . Results The general prevalence of ED in this study was 58.9 % . Sixty-seven ( 47.2 % ) , 16 ( 11.3 % ) and 59(41.5 % ) respondents had mild , moderate and severe ED respectively . Age , hypertension , use of anti-hypertensive drugs , diabetes mellitus and heart disease all had significant unadjusted associations with ED , but their adjusted associations were not statistically significant . Diabetes mellitus maintained a positive statistically significant relationship with ED after adjustment for potential confounders [ OR= 8.31(95 % CI 1.02 - 67.65 ) , P= 0.048 ] . Conclusion The prevalence of ED is high among south-western Nigeria male adults . Physicians , especially primary care ones , need to pay more attention to the sexual history of their patients in order to diagnose and manage ED more frequently
In the meta- analysis , tadalafil and sildenafil appeared to have similar efficacies and overall adverse event rates .
However , compared with sildenafil , tadalafil significantly improved psychological outcomes .
Furthermore , the patients and their partners preferred tadalafil over sildenafil , and no significant difference was found in the adherence and persistence rates between tadalafil and sildenafil .
Additionally , the myalgia and back pain rates were higher and the flushing rate was lower with tadalafil than with sildenafil .
Conclusion Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients ’ sexual confidence .
Furthermore , patients and their partners prefer tadalafil to sildenafil .
Hence , tadalafil may be a better choice for ED treatment
Aims Erectile dysfunction ( ED ) is a major care problem worldwide .
Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED .
This systematic review and meta- analysis were conducted to directly compare tadalafil with sildenafil for the treatment of ED .