Moreover , there was nonlinear association between duration of psyllium consumption , BMI and WC .
Conclusion : Psyllium supplementation does not reduce body weight , BMI , and WC significantly
Abstract Background : Previous studies reported inconsistent findings regarding the effects of psyllium supplementation on  obesity measures .
This systematic review and meta- analysis was performed to summarize data from available r and omized clinical trials ( RCTs ) on the effect of psyllium supplementation on  body weight , body mass index ( BMI ) , and waist circumference ( WC ) in adults .
Gastrointestinal side effects of orlistat may be prevented by concomitant prescription of natural fibers (psyllium mucilloid)
OBJECTIVES : This placebo-controlled open study was design ed to test the hypothesis that most of the gastrointestinal ( GI ) side events induced by treatment of obese patients with orlistat ( a gastrointestinal lipase inhibitor ) could be prevented or ameliorated by concomitant use of natural fibers ( psyllium mucilloid ) . DESIGN : Two groups of obese women ( BMI > 27 kg/m2 ) were treated with orlistat 120 mg three times a day . One group ( A , n=30 ) was r and omized to receive orlistat and , approximately 6.0 g of orange-flavored psyllium mucilloid dissolved in water and the other group ( B , n=30 ) received orlistat and orange-flavored placebo . At the end of 30 days and 2 weeks of washout , group A switched to placebo and group B received psyllium while continuing orlistat three times a day . SUBJECTS : Sixty professional women , more than 21-y-old with a body mass index ( BMI ) between 27.3 and 48.0 kg/m2 , who were not receiving any other medication . MEASUREMENTS : Assessment s included weekly visits to attending physician , filling a form in which GI events were recorded , monthly measurements of body weight , blood pressure and serum lipids . The frequency and severity of GI events were evaluated by a score system , based on information provided by the patients . RESULTS : Both groups A and B significantly lost ( P<0.01 ) weight after 60 days of orlistat ( A=96.8 to 94.9 kg and B=98.7 to 96.5 kg ) . Similarly , BMI values declined significantly in both groups . While in the psyllium plus orlistat group ( group A ) the mean ±s.e.m . of the scores reflecting GI events was 13.0±1.8 , the placebo plus orlistat group ( B ) had a value of 35.9±2.7 ( P<0.01 ) . When the reverse situation was instituted the placebo and orlistat group presented a mean score of 36.1±3.6 and the psyllium plus orlistat a mean score of 8.9±1.5 ( P<0.01 ) . CONCLUSIONS : Psyllium hydrophilic mucilloid concomitantly prescribed to obese patients receiving 120 mg of orlistat three times a day is an effective and safe adjunct therapy that is helpful in controlling the GI side effects of this pancreatic lipase inhibitor
Moreover , there was nonlinear association between duration of psyllium consumption , BMI and WC .
Conclusion : Psyllium supplementation does not reduce body weight , BMI , and WC significantly
Abstract Background : Previous studies reported inconsistent findings regarding the effects of psyllium supplementation on  obesity measures .
This systematic review and meta- analysis was performed to summarize data from available r and omized clinical trials ( RCTs ) on the effect of psyllium supplementation on  body weight , body mass index ( BMI ) , and waist circumference ( WC ) in adults .