Overall , lactobacilli were beneficial for the treatment of patients with bacterial vaginosis .
No clear benefit was seen for c and idiasis or urinary tract infection .
In conclusion , the use of certain lactobacillus strains such as L. rhamnosus GR-1 and L. reuteri for prevention and treatment of recurrent urogenital infection is promising , especially for recurrent bacterial vaginosis .
Abstract Probiotics are increasingly being used to treat and prevent urogenital infections .
However , a critical assessment of their efficacy in major urogenital infections is lacking .
We report the results of a systematic review to determine the efficacy of probiotics for prevention or treatment of three major urogenital infections : bacterial vaginosis , vulvovaginal c and idiasis , and urinary tract infection .
Why Do Different Criteria for ‘Cure’ Yield Different Conclusions in Comparing Two Treatments for Bacterial Vaginosis?
Objective : The objective of this study was to determine why different criteria for response to treatment of bacterial vaginosis ( BV ) led to markedly different conclusions about treatment efficacy in a r and omized trial comparing metronidazole gel versus metronidazole/nystatin ovules . Study : We compared the impact of two treatment regimens on individual components of Amsel and Nugent criteria at follow-up visits 14 , 42 , and 104 days after initiating treatment . Results : Compared with gel , ovules more effectively eliminated amines , clue cells , and Gardnerella , Prevotella , or Mobiluncus morphotypes from vaginal fluid , thus achieving cure based on “ usual ” criteria ( absence of BV by Amsel or Nugent criteria ) , but did not more effectively restore Lactobacillus morphotypes or lower vaginal pH , thus not meeting Federal Drug Administration ( FDA ) criteria for cure . Conclusion : Because early vaginal recolonization by lactobacilli was poor after both gel and ovules , FDA draft criteria for cure missed marked differences in treatment efficacies against Gardnerella , clue cells , and amines . Cure defined more “ usually ” may give more useful information
Overall , lactobacilli were beneficial for the treatment of patients with bacterial vaginosis .
No clear benefit was seen for c and idiasis or urinary tract infection .
In conclusion , the use of certain lactobacillus strains such as L. rhamnosus GR-1 and L. reuteri for prevention and treatment of recurrent urogenital infection is promising , especially for recurrent bacterial vaginosis .
Abstract Probiotics are increasingly being used to treat and prevent urogenital infections .
However , a critical assessment of their efficacy in major urogenital infections is lacking .
We report the results of a systematic review to determine the efficacy of probiotics for prevention or treatment of three major urogenital infections : bacterial vaginosis , vulvovaginal c and idiasis , and urinary tract infection .