The MFSI-SF demonstrated moderate test-retest reliability in a small number of studies .
The MFSI-SF fatigue subscales were positively correlated with measures of distress , depressive , and anxious symptoms .
Purpose Fatigue is a subjective complaint that is believed to be multifactorial in its etiology and multidimensional in its expression .
Fatigue may be experienced by individuals in different dimensions as physical , mental , and emotional tiredness .
The purpose s of this study were to review and characterize the use of the 30-item Multidimensional Fatigue Symptom Inventory-Short Form ( MFSI-SF ) in published studies and to evaluate the available evidence for its psychometric properties .
A multi-nutrient supplement reduced markers of inflammation and improved physical performance in active individuals of middle to older age: a randomized, double-blind, placebo-controlled study
Background While exercise acts to combat inflammation and aging , the ability to exercise may itself be compromised by inflammation and inflammation 's impact on muscle recovery and joint inflammation . A number of nutritional supplements have been shown to reduce inflammation and improve recovery . The purpose of the current investigation was to examine the effect of a multi-nutrient supplement containing branched chain amino acids , taurine , anti-inflammatory plant extracts , and B vitamins on inflammatory status , endothelial function , physical function , and mood in middle-aged individuals . Methods Thirty-one healthy and active men ( N = 16 , mean age 56 ± 6.0 yrs ) and women ( N = 15 , mean age = 52 ± 7.5 yrs ) participated in this investigation . Subjects completed one 28 day cycle of placebo supplementation and one 28 day cycle of multi-nutrient supplementation ( separated by a one week washout period ) in a balanced , r and omized , double-blind , cross-over design . Subjects completed weekly perceptual logs ( PROMIS-57 , KOOS ) and pre- and post- testing around the supplementation period . Testing consisted of brachial artery flow mediated dilation ( FMD ) , blood measures , and physical performance on vertical jump , h and grip strength , and balance ( dispersion from center of pressure ) . Significance for the investigation was p ≤ 0.05 . Results IL-6 significantly decreased in both men ( from 1.2 ± 0.2 to 0.7 ± 0.4 pg·mL-1 ) and women ( from 1.16 ± 0.04 to 0.7 ± 0.4 pg·mL-1 ) . Perceived energy also improved for both men ( placebo : 1.8 ± 0.7 ; supplement : 3.7 ± 0.8 AUC ) and women ( placebo : 1.2 ± 0.7 ; supplement : 2.8 ± 0.8 AUC ) . Alpha-1-antichymotrypsin ( from 108.9 ± 38.6 to 55.5 ± 22.2 ug·mL-1 ) , Creatine Kinase ( from 96 ± 34 to 67 ± 23 IU·L-1 ) , general pain , and joint pain decreased in men only , while anxiety and balance ( from 0.52 ± 0.13 to 0.45 ± 0.12 cm ) improved in women only . Men showed increased performance in vertical jump power ( from 2642 ± 244 to 3134 ± 282 W ) and grip strength ( from 42.1 ± 5.9 to 48.5 ± 4.9 kg ) . Conclusions A multi-nutrient supplement is effective in improving inflammatory status in both men and women , markers of pain , joint pain , strength , and power in men only , and both anxiety and balance ( a risk factor for hip fracture ) in women . Therefore , a multi-nutrient supplement may help middle-aged individuals to prolong physical function and maintain a healthy , active lifestyle
The MFSI-SF demonstrated moderate test-retest reliability in a small number of studies .
The MFSI-SF fatigue subscales were positively correlated with measures of distress , depressive , and anxious symptoms .
Purpose Fatigue is a subjective complaint that is believed to be multifactorial in its etiology and multidimensional in its expression .
Fatigue may be experienced by individuals in different dimensions as physical , mental , and emotional tiredness .
The purpose s of this study were to review and characterize the use of the 30-item Multidimensional Fatigue Symptom Inventory-Short Form ( MFSI-SF ) in published studies and to evaluate the available evidence for its psychometric properties .