Quantitative relations between baseline iron status , study duration , and iron dose on changes in iron-status biomarkers , which were generated from the meta-analyses , can be used to predict effects of trials of iron supplementation and fortification and to design iron-intervention programs
BACKGROUND The response of status biomarkers to an increase in iron supply depends on several physiologic and environmental factors , which make it difficult to predict the outcome of an intervention .
OBJECTIVE We assessed effects of baseline iron status , sex , menopausal status , duration of intervention , iron form , and daily dose on the change in iron status in response to iron supplementation .
The effect of iron supplementation on the physical work capacity in the elderly.
. The effect of a high oral iron supplementation ( 120 mg day ) on the physical work capacity has been studied in a group of apparently healthy men and women of ages 58–71 years , and this effect was correlated with the initial values of and changes in some variables constituting usual clinical estimates of the state of iron nutrition . The increase in physical work capacity was about 4 % higher in men and about 12 % higher in women in the group supplemented with iron than in the control ( placebo ) group . In the control group there was a positive correlation between increase in physical work capacity and initial value for stainable iron in the bone marrow , and a negative correlation between increase in physical work capacity and decrease in the value for stainable iron in the bone marrow ; it is pointed out that these findings should not be expected in the iron-supplemented group , where variations in the depot iron will be of less influence . In the iron-supplemented group the total iron binding capacity decreased significantly , while the remaining variables constituting estimates of the state of iron nutrition showed no significant changes . The increase in physical work capacity in the iron-supplemented group did not appear to be correlated to the initial value either for haemoglobin concentration or for other variables estimating the state of iron nutrition . It is concluded that in apparently healthy people the increase in physical work capacity during moderate training is related to the availability of iron
Quantitative relations between baseline iron status , study duration , and iron dose on changes in iron-status biomarkers , which were generated from the meta-analyses , can be used to predict effects of trials of iron supplementation and fortification and to design iron-intervention programs
BACKGROUND The response of status biomarkers to an increase in iron supply depends on several physiologic and environmental factors , which make it difficult to predict the outcome of an intervention .
OBJECTIVE We assessed effects of baseline iron status , sex , menopausal status , duration of intervention , iron form , and daily dose on the change in iron status in response to iron supplementation .