There was strong evidence that duration away from work from both MSK or pain-related conditions and MH conditions were significantly reduced by multi-domain interventions encompassing at least two of the three domains .
There was moderate evidence that these multi-domain interventions had a positive impact on cost outcomes .
There was strong evidence that cognitive behavioural therapy interventions that do not also include workplace modifications or service coordination components are not effective in helping workers with MH conditions in RTW .
Evidence for the effectiveness of other single-domain interventions was mixed , with some studies reporting positive effects and others reporting no effects on lost time and work functioning .
Purpose The objective of this systematic review was to synthesize evidence on the effectiveness of workplace-based return-to-work ( RTW ) interventions and work disability management ( DM ) interventions that assist workers with musculoskeletal ( MSK ) and pain-related conditions and mental health ( MH ) conditions with RTW .
Cost-Utility Analysis of a Collaborative Care Intervention for Major Depressive Disorder in an Occupational Healthcare Setting
Purpose Major depression is associated with high levels of absence and reduced productivity . Therefore the costs to society are high . The aim of this study was to evaluate the cost-utility of collaborative care for major depressive disorder ( MDD ) compared to care as usual in an occupational healthcare setting . A societal perspective was taken . Methods In this r and omised controlled trial , 126 sick-listed workers with MDD were included ( 65 collaborative care ,  61 care as usual )  . Baseline measurements and follow up measures ( 3 , 6 , 9 and 12 months ) were assessed by question naire . We applied the Trimbos/iMTA question naire for costs associated with psychiatric illness , the SF-HQL and the EQ-5D respectively measuring the health care utilization , production losses and general health related quality of life . Results The average annual healthcare costs in the collaborative care group were € 3,874 ( 95 % CI € 2,778–€5,718 ) compared to € 4,583 ( 95 % CI € 3,108–€6,794 ) in the care as usual group . The average quality of life years ( QALY ’s ) gained were lower in the collaborative care group , 0.05 QALY . The majority of the ICERS ( 69 % ) indicate that collaborative care  is less costly but also less effective  than care as usual . Including the productivity costs did not change this result . Conclusions The cost-utility analysis showed that collaborative care generated reduced costs and a reduction in effects compared to care as usual and was therefore not a cost-effective intervention
There was strong evidence that duration away from work from both MSK or pain-related conditions and MH conditions were significantly reduced by multi-domain interventions encompassing at least two of the three domains .
There was moderate evidence that these multi-domain interventions had a positive impact on cost outcomes .
There was strong evidence that cognitive behavioural therapy interventions that do not also include workplace modifications or service coordination components are not effective in helping workers with MH conditions in RTW .
Evidence for the effectiveness of other single-domain interventions was mixed , with some studies reporting positive effects and others reporting no effects on lost time and work functioning .
Purpose The objective of this systematic review was to synthesize evidence on the effectiveness of workplace-based return-to-work ( RTW ) interventions and work disability management ( DM ) interventions that assist workers with musculoskeletal ( MSK ) and pain-related conditions and mental health ( MH ) conditions with RTW .