No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .
Differential oxidation of individual dietary fatty acids in humans.
BACKGROUND Dietary fatty acids that are more prone to oxidation than to storage may be less likely to lead to obesity . OBJECTIVE The aim of this study was to determine the effect of chain length , degree of unsaturation , and stereoisomeric effects of unsaturation on the oxidation of individual fatty acids in normal-weight men . DESIGN Fatty acid oxidation was examined in men consuming a weight-maintenance diet containing 40 % of energy as fat .  After consuming the diet for 1 wk , subjects were fed fatty acids labeled with (13)C in the methyl or carboxyl position ( 10 mg/kg body wt ) . The fatty acids fed in r and om order were laurate , palmitate , stearate , oleate , elai date ( the trans isomer of oleate ) , linoleate , and linolenate blended in a hot liquid meal . Breath sample s were collected for the next 9 h and the oxidation of each fatty acid was assessed by examining liberated (13)CO(2 ) in breath . RESULTS Cumulative oxidation over the 9-h test ranged from a high of 41 % of the dose for laurate to a low of 13 % of the dose for stearate . Of the 18-carbon fatty acids , linolenate was the most highly oxidized and linoleate appeared to be somewhat conserved . (13)C recovery in breath from the methyl-labeled fatty acids was approximately 30 % less than that from the carboxyl-labeled fatty acids . CONCLUSIONS In summary , lauric acid is highly oxidized , whereas the polyunsaturated and monounsaturated fatty acids are fairly well oxidized . Oxidation of the long-chain , saturated fatty acids decreases with increasing carbon number
No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .