Collectively , these outcomes support a volumetric dilution of vitamin D. The slopes of the respective regression lines , however , indicate a smaller increase in 25OHD than would be expected from a direct mobilization of stores into the circulation .
Hence , sequestration of 25OHD and its conversion to inactive metabolites would also play a role .
The purpose of this review was to confirm a volumetric dilution of vitamin D in obesity .
It was based on the hypothesis that weight loss , particularly fat loss , would increase serum 25-hydroxyvitamin D ( 25OHD ) in the obese .
Dairy Foods in a Moderate Energy Restricted Diet Do Not Enhance Central Fat, Weight, and Intra-Abdominal Adipose Tissue Losses nor Reduce Adipocyte Size or Inflammatory Markers in Overweight and Obese Adults: A Controlled Feeding Study
Background . Research on dairy foods to enhance weight and fat loss when incorporated into a modest weight loss diet has had mixed results . Objective . A 15-week controlled feeding study to determine if dairy foods enhance central fat and weight loss when incorporated in a modest energy restricted diet of overweight and obese adults . Design . A 3-week run-in to establish energy needs ; a 12-week 500 kcal/d energy reduction with 71 low-dairy-consuming overweight and obese adults r and omly assigned to diets : ≤1 serving dairy/d ( low dairy , LD ) or ≤4 servings dairy/d ( adequate dairy , AD ) . All foods were weighed and provided by the metabolic kitchen . Weight , fat , intra-abdominal adipose tissue ( IAAT ) , subcutaneous adipose tissue ( SAT ) macrophage number , SAT inflammatory gene expression , and circulating cytokines were measured . Results . No diet differences were observed in weight , fat , or IAAT loss ; nor SAT mRNA expression of inflammation , circulating cytokines , fasting lipids , glucose , or insulin . There was a significant increase ( P = 0.02 ) in serum 25-hydroxyvitamin D in the AD group . Conclusion . Whether increased dairy intake during weight loss results in greater weight and fat loss for individuals with metabolic syndrome deserves investigation . Assessment of appetite , hunger , and satiety with followup on weight regain should be considered
Collectively , these outcomes support a volumetric dilution of vitamin D. The slopes of the respective regression lines , however , indicate a smaller increase in 25OHD than would be expected from a direct mobilization of stores into the circulation .
Hence , sequestration of 25OHD and its conversion to inactive metabolites would also play a role .
The purpose of this review was to confirm a volumetric dilution of vitamin D in obesity .
It was based on the hypothesis that weight loss , particularly fat loss , would increase serum 25-hydroxyvitamin D ( 25OHD ) in the obese .