In conclusion , a number of new active drugs were found to improve some cognitive functions , in particular verbal episodic memory .
Pharmacological cognitive enhancement refers to improvement in cognitive functions after drug use in healthy individuals .
This popular topic attracts attention both from the general public and the scientific community .
The objective was to explore innovative mechanisms of psychostimulant 's action , whose potential effectiveness was assessed in r and omized placebo-controlled trials ( RCTs ) .
Evidence That a Positive Modulator of AMPA-Type Glutamate Receptors Improves Delayed Recall in Aged Humans
Elderly subjects ( 65 - 76 years ) were tested for recall of nonsense syllables prior to and after oral administration of 1-(quinoxalin-6 ylcarbonyl)piperidine ( CX516 ) , a central ly active drug that enhances currents mediated by AMPA-type glutamate receptors . A significant and positive drug effect was found for delayed ( 5 min ) recall at 75 min posttreatment ; average scores for the highest dose group were more than twofold greater than for the placebo group . The drug had no evident influence on heart rate or self- assessment of several psychological variables
In conclusion , a number of new active drugs were found to improve some cognitive functions , in particular verbal episodic memory .
Pharmacological cognitive enhancement refers to improvement in cognitive functions after drug use in healthy individuals .
This popular topic attracts attention both from the general public and the scientific community .
The objective was to explore innovative mechanisms of psychostimulant 's action , whose potential effectiveness was assessed in r and omized placebo-controlled trials ( RCTs ) .