The benefits of antioxidants or DHA/EPA supplementation for CF , although observed in some studies , are not consistent enough to recommend routine use of these supplements .
Antioxidant micronutrients and essential fatty acids supplementation intake appears to have a protective effect in some diseases such as cardiovascular disease , cancer , and asthma .
The aim of this study was to perform a systematic review to evaluate the effects of these nutrients on nutritional and clinical outcomes of patients with cystic fibrosis ( CF ) .
This is a systematic review of r and omized clinical trials ( RCTs ) in CF .
Predictive 5-year survivorship model of cystic fibrosis.
The objective of this study was to create a 5-year survivorship model to identify key clinical features of cystic fibrosis . Such a model could help research ers and clinicians to evaluate therapies , improve the design of prospect i ve studies , monitor practice patterns , counsel individual patients , and determine the best c and i date s for lung transplantation . The authors used information from the Cystic Fibrosis Foundation Patient Registry ( CFFPR ) , which has collected longitudinal data on approximately 90 % of cystic fibrosis patients diagnosed in the United States since 1986 . They developed multivariate logistic regression models by using data on 5,820 patients r and omly selected from 11,630 in the CFFPR in 1993 . Models were tested for goodness of fit and were vali date d for the remaining 5,810 patients for 1993 . The vali date d 5-year survivorship model included age , forced expiratory volume in 1 second as a percentage of predicted normal , gender , weight-for-age z score , pancreatic sufficiency , diabetes mellitus , Staphylococcus aureus infection , Burkerholderia cepacia infection , and annual number of acute pulmonary exacerbations . The model provides insights into the complex nature of cystic fibrosis and supplies a rigorous tool for clinical practice and research
The benefits of antioxidants or DHA/EPA supplementation for CF , although observed in some studies , are not consistent enough to recommend routine use of these supplements .
Antioxidant micronutrients and essential fatty acids supplementation intake appears to have a protective effect in some diseases such as cardiovascular disease , cancer , and asthma .
The aim of this study was to perform a systematic review to evaluate the effects of these nutrients on nutritional and clinical outcomes of patients with cystic fibrosis ( CF ) .
This is a systematic review of r and omized clinical trials ( RCTs ) in CF .