The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .
Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial.
Pulmonary problems are among the most frequent chronic complications of sulfur mustard ( SM ) intoxication and are often accompanied by deregulated production of pro-inflammatory cytokines . Curcuminoids , comprising curcumin , demethoxycurcumin and bisdemethoxycurcumin , are phytochemicals with remarkable anti-inflammatory properties that are derived from dried rhizomes of the plant Curcuma longa L. ( turmeric ) . The present pilot study aim ed to investigate the clinical effects of supplementation with curcuminoids on markers of pulmonary function and systemic inflammation in SM-intoxicated subjects . In a r and omized double-blind placebo-controlled trial , 89 male subjects who were suffering from chronic SM-induced pulmonary complications were recruited and assigned to either curcuminoids ( 500 mg TID per oral ; n=45 ) or placebo ( n=44 ) for a period of 4 weeks . Efficacy measures were changes in the spirometric parameters ( FVC , FEV1 , FEV1/FVC ) and serum levels of inflammatory mediators including interleukins 6 ( IL-6 ) and 8 ( IL-8 ) , tumor necrosis factor-α ( TNFα ) , transforming growth factor-β ( TGFβ ) , high-sensitivity C-reactive protein ( hs-CRP ) , calcitonin gene related peptide ( CGRP ) , substance P and monocyte chemotactic protein-1 ( MCP-1 ) . 78 subjects completed the trial .  Although FEV1 and FVC remained comparable between the groups , there was a greater effect of curcuminoids vs. placebo in improving FEV1/FVC ( p=0.002 ) . Curcuminoids were also significantly more efficacious compared to placebo in modulating all assessed inflammatory mediators : IL-6 ( p<0.001 ) , IL-8 ( p=0.035 ) , TNFα ( p<0.001 ) , TGFβ ( p<0.001 ) , substance P ( p=0.016 ) , hs-CRP ( p<0.001 ) , CGRP ( p<0.001 ) and MCP-1 ( p<0.001 ) . Curcuminoids  were safe and well-tolerated throughout the trial . Short-term adjunctive therapy with curcuminoids  can suppress systemic inflammation in patients suffering from SM-induced chronic pulmonary complications
The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .