SET was still beneficial for maximal and pain-free walking distances at 12 months , but it did not have a significant effect on quality of life parameters .
AUTHORS ' CONCLUSIONS SET has statistically significant benefit on treadmill walking distance ( maximal and pain-free ) compared with non-supervised regimens .
BACKGROUND Although supervised exercise therapy is considered to be of significant benefit for people with leg pain ( peripheral arterial disease ( PAD ) ) , implementing supervised exercise programs ( SETs ) in daily practice has limitations .
This is an up date of a review first published in 2006 .
OBJECTIVES The main objective of this review was to provide an accurate overview of studies evaluating the effects of supervised versus non-supervised exercise therapy on maximal walking time or distance on a treadmill for people with intermittent claudication .
Peripheral Arterial Occlusive Disease: Prognostic Value of Signs, Symptoms, and the Ankle-Brachial Pressure Index
Objectives . To determine whether different levels of the ankle-brachial pressure index ( ABPI ) are associated with an increased risk for progressive limbischemia , nonfatal and fatal cardiovascular events . To investigate the prognostic value of signs and symptoms associated with peripheral arterial occlusive disease ( PAOD ) . Design . Prospect i ve follow-up study . Setting . Eighteen general practice centers in the Netherl and s. Participants . Three thous and six hundred forty-nine participants ( 53 % female ) with a mean age of 59 years ( range : 40 - 78 years ) . Main outcome measures . Progressive limbischemia , cardiovascular morbidity and mortality . Results . At baseline , 458 participants had PAOD , defined as an ABPI < 0.95 . Among these , 148 ( 32.2 % ) had an ABPI < 0.70 . Cox proportional hazards models showed that after a mean follow-up period of 7.2 years , PAOD patients with an ABPI < 0.70 were at higher risk for cardiovascular death , compared with participants with a moderately reduced ABPI ( < 0.95 - 0.70 ) : HR 2.3 versus 1.2 . Older age , complaints of intermittent claudication , abnormal pedal pulses , elevated blood pressure , and coexisting cardiovascular disease at baseline were also significant independent prognostic factors for one or more of the adverse outcome events in these patients . Conclusion . The ABPI is inversely associated with cardiovascular mortality  in PAOD patients . A low ABPI is an independent predictor for cardiovascular mortality in PAOD patients
SET was still beneficial for maximal and pain-free walking distances at 12 months , but it did not have a significant effect on quality of life parameters .
AUTHORS ' CONCLUSIONS SET has statistically significant benefit on treadmill walking distance ( maximal and pain-free ) compared with non-supervised regimens .
BACKGROUND Although supervised exercise therapy is considered to be of significant benefit for people with leg pain ( peripheral arterial disease ( PAD ) ) , implementing supervised exercise programs ( SETs ) in daily practice has limitations .
This is an up date of a review first published in 2006 .
OBJECTIVES The main objective of this review was to provide an accurate overview of studies evaluating the effects of supervised versus non-supervised exercise therapy on maximal walking time or distance on a treadmill for people with intermittent claudication .