CONCLUSIONS This review provides some support to the notion that patients experiencing antipsychotic side-effects are at risk of developing more negative attitudes toward medication .
BACKGROUND Antipsychotics are associated with a wide range of side-effects .
Many patients experience antipsychotics as unpleasant and something they would rather avoid , leading some of them to discontinue taking their medication .
The importance of evaluating the patients ' perspective , especially their attitudes toward medication in the presence of side-effects , has long been emphasized .
However , no definite conclusion has been made to date on the relationship between antipsychotic side-effects and attitudes toward medication .
OBJECTIVES The objective of this systematic review was to determine the best available evidence regarding the impact of antipsychotic side-effects on attitudes toward medication in patients with schizophrenia and related disorders , which include schizoaffective and schizophreniform disorders .
SEARCH STRATEGY The search aim ed to find published studies using a range of data bases .
Psychological predictors of insight and compliance in psychotic patients.
BACKGROUND A possible neuropsychological basis for poor insight in psychosis has been proposed . Consistent supporting evidence for this is lacking . METHOD Seventy-four consecutive acutely psychotic in- patients who were recruited for a r and omised controlled trial of compliance therapy  were given a battery of neuropsychological tests , along with a comprehensive clinical assessment , before and after the intervention . RESULTS Performance on neuropsychological tests improved during the patients ' admission and treatment in hospital , as did symptoms and levels of insight . Cognitive function showed no relationship to insight and compliance initially , and very little after the intervention . Factors related to insight and compliance prior to discharge included : diagnosis , attitudes to medication , side-effects , being a detained patient , and whether or not compliance therapy was given . CONCLUSIONS Clinical variables and attitudes to treatment appear to be more relevant to compliance and the development of insight in acute psychosis than neuropsychological impairment
CONCLUSIONS This review provides some support to the notion that patients experiencing antipsychotic side-effects are at risk of developing more negative attitudes toward medication .
BACKGROUND Antipsychotics are associated with a wide range of side-effects .
Many patients experience antipsychotics as unpleasant and something they would rather avoid , leading some of them to discontinue taking their medication .
The importance of evaluating the patients ' perspective , especially their attitudes toward medication in the presence of side-effects , has long been emphasized .
However , no definite conclusion has been made to date on the relationship between antipsychotic side-effects and attitudes toward medication .
OBJECTIVES The objective of this systematic review was to determine the best available evidence regarding the impact of antipsychotic side-effects on attitudes toward medication in patients with schizophrenia and related disorders , which include schizoaffective and schizophreniform disorders .
SEARCH STRATEGY The search aim ed to find published studies using a range of data bases .