No significant changes were observed for blood lipids , anthropometric measures , HbA1c and fasting glucose .
The present systematic review provides evidence for beneficial effects of long-term interventions administering a low glycemic index/load diet with respect to fasting insulin and pro-inflammatory markers such as C-reactive protein which might prove to be helpful in the primary prevention of obesity-associated diseases
AIM The aim of the present meta- analysis was to investigate the long-term effects of glycemic index-related diets in the management of obesity with a special emphasis on the potential benefits of low glycemic index/load ( GI/GL ) in the prevention of obesity-associated risks .
A low-glycemic load diet reduces serum C-reactive protein and modestly increases adiponectin in overweight and obese adults.
Low-glycemic load ( GL ) diets improve insulin resistance and glucose homeostasis in individuals with diabetes . Less is known about whether low-GL diets , independent of weight loss , improve the health profile for persons without diabetes or other preexisting conditions . We conducted a r and omized , cross-over feeding study testing low- compared to High-GL diets on biomarkers of inflammation and adiposity in healthy adults . Eighty participants ( n = 40 with BMI 18.5 - 24.9 kg/m² ; n = 40 with BMI 28.0 - 40.0 kg/m² ) completed two 28-d feeding periods in r and om order where one period was a high-GL diet ( mean GL/d = 250 ) and the other a low-GL diet ( mean GL/d = 125 ) . Diets were isocaloric with identical macronutrient content ( as percent energy ) . All food was provided and participants maintained weight and usual physical activity . Height , weight , and DXA were measured at study entry and weight assessed again thrice per week . Blood was drawn from fasting participants at the beginning and end of each feeding period and serum concentrations of high-sensitivity CRP , serum amyloid A , IL-6 , leptin , and adiponectin were measured . Linear mixed models tested the intervention effect on the biomarkers ; models were adjusted for baseline biomarker concentrations , diet sequence , feeding period , age , sex , and body fat mass . Among participants with high-body fat mass ( > 32.0 % for males and > 25.0 % for females ) , the low-GL diet reduced CRP ( P = 0.02 ) and marginally increased adiponectin ( P = 0.06 ) . In conclusion , carbohydrate quality , independent of energy , is important . Dietary patterns emphasizing low-GL foods may improve the inflammatory and adipokine profiles of overweight and obese individuals
No significant changes were observed for blood lipids , anthropometric measures , HbA1c and fasting glucose .
The present systematic review provides evidence for beneficial effects of long-term interventions administering a low glycemic index/load diet with respect to fasting insulin and pro-inflammatory markers such as C-reactive protein which might prove to be helpful in the primary prevention of obesity-associated diseases
AIM The aim of the present meta- analysis was to investigate the long-term effects of glycemic index-related diets in the management of obesity with a special emphasis on the potential benefits of low glycemic index/load ( GI/GL ) in the prevention of obesity-associated risks .