Conclusion The evidence is limited to suggest moxibustion is an effective supportive cancer care in nausea and vomiting .
Background Moxibustion is a traditional Chinese method that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points .
Considering moxibustion is closely related to acupuncture , it seems pertinent to evaluate the effectiveness of moxibustion as a treatment of symptoms of cancer .
The objective of this review was to systematic ally assess the effectiveness of moxibustion for supportive cancer care .
Effect of pre-moxibustion on apoptosis and proliferation of gastric mucosa cells.
AIM To observe the effects of pre-moxibustion on apoptosis and proliferation of gastric mucosal cell in rats with stress-induced ulcer , and to analyze the relationship between those effects and the expression of heat-shock protein 70 ( HSP70 ) . METHODS Sixty healthy Sprague Dawley rats were r and omly assigned into four groups , namely group A , B , C and D. The animal model of stress ulcer was established by water immersion and restraint stress . The rats in group A , B , and D served as the restraint , model , and non-acupoint controls , respectively , while those in group C received moxibustion at Zusanli and Liangmen points . Immunohistochemical methodology was used to detect the expression of HSP70 , apoptosis index ( AI , multiply 10(-6)/microm(2 ) ) and proliferation index ( PCNA-LI , multiply 10(-6)/microm(2 ) ) . The mucosal expression of transforming growth factor alpha(TGF-alpha ) was detected by radioimmunoassay . RESULTS Moxibustion at Zusanli and Liangmen points significantly decreased the gastric injury and the apoptosis of gastric mucosal cells , while markedly increased the mucosal expression of TGF-alpha and HSP70 as well as the proliferation of gastric mucosal cells . Compared with group A , ulcer index ( UI ) ( 26.8 + /- 9.8 vs 12.0 + /- 5.9 , P < 0.01 ) , AI ( 9.6 + /- 4.2 vs 4.4 + /- 2.6 , P < 0.05 ) and expression of HSP70 ( 9.6 + /- 4.2 vs 4.4 + /- 2.6 , P < 0.05 ) were significantly increased , but the content of TGF-alpha ( 104.7 + /- 51.2 pg/mL vs 254.0 + /- 86.9 pg/mL , P < 0.01 ) and PCNA-LI ( 6.9 + /- 4.7 vs 14.9 + /- 4.6 , P < 0.05 ) were significantly decreased in group B. However , ulcer index values ( UI ) and AI were obviously lower in group C compared to groups B and D ( 14.1 + /- 5.4 vs 26.8 + /- 9.8 and 26.2 + /- 7.7 , P < 0.01 ; 3.0 + /- 1.6 vs 9.6 + /- 4.2 and 8.2 + /- 5.2 , P < 0.05 , respectively ) , but content of TGF-alpha ( 237.0 + /- 72.6 pg/mL vs 104.7 + /- 51.2 pg/mL and 154.1 + /- 61.3 pg/mL , P < 0.01 ) and expression of HSP70 ( 0.13 + /- 0.03 vs 0.08 + /- 0.06 and 0.06 + /- 0.04 , P < 0.05 ) were higher in group C. Furthermore , the PCNA-LI was significantly higher in group C than in group B ( 21.6 + /- 4.1 vs 6.9 + /- 4.7 , P < 0.01 ) . CONCLUSION Moxibustion at Zusanli and Liangmen points has a protective effect on rats gastric mucosa in stress-induced gastric ulcer , which is closely related to its actions in promoting synthesis of TGF-alpha and proliferation of gastric mucosal cells , suppressing gastric mucosal cell apoptosis , and up-regulating HSP70 expression
Conclusion The evidence is limited to suggest moxibustion is an effective supportive cancer care in nausea and vomiting .
Background Moxibustion is a traditional Chinese method that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points .
Considering moxibustion is closely related to acupuncture , it seems pertinent to evaluate the effectiveness of moxibustion as a treatment of symptoms of cancer .
The objective of this review was to systematic ally assess the effectiveness of moxibustion for supportive cancer care .