Serenoa repens was not more effective than placebo for treatment of urinary symptoms consistent with BPH
BACKGROUND Benign prostatic hyperplasia ( BPH ) , a nonmalignant enlargement of the prostate , can lead to obstructive and irritative lower urinary tract symptoms ( LUTS ) .
The pharmacologic use of plants and herbs ( phytotherapy ) for the treatment of LUTS associated with BPH is common .
The extract of the berry of the American saw palmetto , or dwarf palm plant , Serenoa repens ( also known by its botanical name of Sabal serrulatum ) , is one of several phytotherapeutic agents available for the treatment of BPH .
OBJECTIVES This systematic review aim ed to assess the effects of Serenoa repens in the treatment of LUTS consistent with BPH .
[Efficacy of pretreatment with Serenoa repens on bleeding associated with transurethral resection of prostate].
AIM Aim of the study is to evaluate the efficacy of a pretreatment with lipidic-sterolic extract of Serenoa repens ( Permixon ) to reduce bleeding during transurethral resection of prostate ( TURP ) in patients with benign prostatic hyperplasia . METHODS This is a monocentric , r and omised versus control group study . We enrolled 108 patients , r and omised either in the experimental group or in the control one . Patients in the experimental group received a pretreatment with Serenoa repens ( 320 mg/die of Permixon ) for at least 8 weeks before the TURP procedure . In the control group patients did not receive any medical treatment before the intervention . RESULTS Out of 108 enrolled patients , 88 were evaluated per protocol . In the pretreated group the perioperative bleeding was significantly lower than in the control one ( respectively 124 vs 287 ml ) and the need of transfusion decreased remarkably . Moreover , in the pretreated group , the duration of postoperative catheterization ( respectively 3 vs 5 days ) and the evaluated hematological parameters ( red cells 4.5 vs 4 million , hemoglobin 13.4 vs 11.9 g , hematocrit 40 % vs 35 % ) were significantly lower than in the control group . CONCLUSION The pretreatment with Serenoa repens , before TURP procedure , improves the efficacy of the procedure itself and reduces the risk of complications , in particular perioperative bleeding and duration of postoperative catheterization
Serenoa repens was not more effective than placebo for treatment of urinary symptoms consistent with BPH
BACKGROUND Benign prostatic hyperplasia ( BPH ) , a nonmalignant enlargement of the prostate , can lead to obstructive and irritative lower urinary tract symptoms ( LUTS ) .
The pharmacologic use of plants and herbs ( phytotherapy ) for the treatment of LUTS associated with BPH is common .
The extract of the berry of the American saw palmetto , or dwarf palm plant , Serenoa repens ( also known by its botanical name of Sabal serrulatum ) , is one of several phytotherapeutic agents available for the treatment of BPH .
OBJECTIVES This systematic review aim ed to assess the effects of Serenoa repens in the treatment of LUTS consistent with BPH .