A literature analysis supported links between  sugar  intake and both total energy intake and body weight gain , and between sugar intake and blood triglycerides independently of total energy intake .
The effects of sugar on blood triglycerides were shown to be mediated by the fructose component of sucrose and were observed with an intake of fructose > 50 g/day .
In addition , prospect i ve cohort studies showed associations between sugar intake and the risk of diabetes/insulin resistance , cardiovascular diseases , NAFLD , and hyperuricemia .
Carbohydrate-induced thermogenesis in obese women. Effect of insulin and catecholamines
Results of studies on diet-induced thermogenesis in obese persons are contradictory . A number of factors have been postulated to mediate the obligatory and facultative component of thermogenesis . This study was design ed to investigate some further factors mediating the carbohydrate- induced thermogenesis in obese women . In 13 obese women , thermogenic responses to glucose and fructose were compared and related to subsequent hormonal changes . The thermogenic effect after fructose ingestion was significantly ( p<0.006 ) higher in comparison with glucose , despite lower values for both glucose and insulin concentrations . Carbohydrate oxidation was significantly higher after fructose ( 81±7 E% vs 62±10 E% p<0.01 ) while oxidation of fat was lower ( 10±9 E% vs 21±12 E% p<0.01 ) . These effects may partly be due to the de novo lipogenesis and /or to changes in cellular metabolism . No clear relationship could be found between thermogenesis and the activity of the sympathetic nervous system , as expressed by urinary catecholamine levels . These results indicate that not insulin but the cellular rate of carbohydrate metabolism is responsible for the thermogenic response to different carbo-nutrients
A literature analysis supported links between  sugar  intake and both total energy intake and body weight gain , and between sugar intake and blood triglycerides independently of total energy intake .
The effects of sugar on blood triglycerides were shown to be mediated by the fructose component of sucrose and were observed with an intake of fructose > 50 g/day .
In addition , prospect i ve cohort studies showed associations between sugar intake and the risk of diabetes/insulin resistance , cardiovascular diseases , NAFLD , and hyperuricemia .