No significant differences were observed for weight , waist circumference , fat mass , blood lipids ( i.e. total cholesterol , LDL-cholesterol , HDL-cholesterol , triacylglycerols ) , C-reactive protein , diastolic and systolic blood pressure , fasting glucose and glycosylated hemoglobin .
Sensitivity analysis of high quality RCTs confirmed the data of the primary analyses , while exclusion of studies with diabetic subjects result ed in an additional benefit of high-protein diets with respect to a more marked increase in HDL-cholesterol .
Conclusion According to the present meta- analysis of long-term RCTs , high-protein diets exerted neither specific beneficial nor detrimental effects on outcome markers of obesity , cardiovascular disease or glycemic control .
Background Meta-analyses of short-term studies indicate favorable effects of higher protein vs. lower protein diets on health outcomes like adiposity or cardiovascular risk factors , but their long-term effects are unknown .
A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women.
Cl aims about the merits or risks of carbohydrate ( CHO ) vs. protein for weight loss diets are extensive , yet the ideal ratio of dietary carbohydrate to protein for adult health and weight management remains unknown . This study examined the efficacy of two weight loss diets with modified CHO/protein ratios to change body composition and blood lipids in adult women . Women ( n = 24 ; 45 to 56 y old ) with body mass indices > 26 kg/m(2 ) were assigned to either a CHO Group consuming a diet with a CHO/protein ratio of 3.5 ( 68 g protein/d ) or a Protein Group with a ratio of 1.4 ( 125 g protein/d ) . Diets were isoenergetic , providing 7100 kJ/d , and similar amounts of fat ( approximately 50 g/d ) . After consuming the diets for 10 wk , the CHO Group lost 6.96 + /- 1.36 kg body weight and the Protein Group lost 7.53 + /- 1.44 kg . Weight loss in the Protein Group was partitioned to a significantly higher loss of fat/lean ( 6.3 + /- 1.2 g/g ) compared with the CHO Group ( 3.8 + /- 0.9 ) . Both groups had significant reductions in serum cholesterol ( approximately 10 % ) , whereas the Protein Group also had significant reductions in triacylglycerols ( TAG ) ( 21 % ) and the ratio of TAG/HDL cholesterol ( 23 % ) . Women in the CHO Group had higher insulin responses to meals and postpr and ial hypoglycemia , whereas women in the Protein Group reported greater satiety . This study demonstrates that increasing the proportion of protein to carbohydrate in the diet of adult women has positive effects on body composition , blood lipids , glucose homeostasis and satiety during weight loss
No significant differences were observed for weight , waist circumference , fat mass , blood lipids ( i.e. total cholesterol , LDL-cholesterol , HDL-cholesterol , triacylglycerols ) , C-reactive protein , diastolic and systolic blood pressure , fasting glucose and glycosylated hemoglobin .
Sensitivity analysis of high quality RCTs confirmed the data of the primary analyses , while exclusion of studies with diabetic subjects result ed in an additional benefit of high-protein diets with respect to a more marked increase in HDL-cholesterol .
Conclusion According to the present meta- analysis of long-term RCTs , high-protein diets exerted neither specific beneficial nor detrimental effects on outcome markers of obesity , cardiovascular disease or glycemic control .
Background Meta-analyses of short-term studies indicate favorable effects of higher protein vs. lower protein diets on health outcomes like adiposity or cardiovascular risk factors , but their long-term effects are unknown .