The evidence supports the WPAI as having test-retest reliability ( reproducibility ) over time ; convergent validity , as indicated by moderate correlations with measures of quality of life and moderate-to-strong correlations with measures of disease activity ; known-groups validity , as indicated by differences in WPAI scores between patients with active and inactive disease ; ability ( sensitivity ) to detect change , as indicated by substantial improvement in scores for patients who achieve remission , accompanied by substantial worsening of scores for patients who relapse ; and , responsiveness to treatment , with improvements in scores following treatments that reduce disease activity .
Patients with ulcerative colitis , a type of inflammatory bowel disease , report negative impacts of disease symptoms on work-related outcomes , including absenteeism and presenteeism .
As a way to better underst and the impact of this disease and its treatment on work-related outcomes , the current review examines the use of the Work Productivity and Activity Impairment Question naire ( WPAI ) , a patient-reported outcomes measure of absenteeism , presenteeism , and impairment in other activities , in studies of patients with ulcerative colitis .
This review assesses the measurement properties of the WPAI in this patient population : its reliability , construct validity , ability to detect change , and responsiveness to effective treatments .
The Validity and Reproducibility of a Work Productivity and Activity Impairment Instrument
Summary The construct validity of a quantitative work productivity and activity impairment ( WPAI ) measure of health outcomes was tested for use in clinical trials , along with its reproducibility when administered by 2 different methods . 106 employed individuals affected by a health problem were r and omised to receive either 2 self-administered question naires ( self administration ) or one self-administered question naire followed by a telephone interview ( interviewer administration ) . Construct validity of the WPAI measures of time missed from work , impairment of work and regular activities due to overall health and symptoms , were assessed relative to measures of general health perceptions , role ( physical ) , role ( emotional ) , pain , symptom severity and global measures of work and interference with regular activity . Multivariate linear regression models were used to explain the variance in work productivity and regular activity by validation measures . Data generated by interviewer-administration of the WPAI had higher construct validity and fewer omissions than that obtained by self-administration of the instrument . All measures of work productivity and activity impairment were positively correlated with measures which had proven construct validity . These validation measures explained 54 to 64 % of variance ( p < 0.0001 ) in productivity and activity impairment variables of the WPAI . Overall work productivity ( health and symptom ) was significantly related to general health perceptions and the global measures of interference with regular activity . The self-administered question naire had adequate reproducibility but less construct validity than interviewer administration . Both administration methods of the WPAI warrant further evaluation as a measure of morbidity
The evidence supports the WPAI as having test-retest reliability ( reproducibility ) over time ; convergent validity , as indicated by moderate correlations with measures of quality of life and moderate-to-strong correlations with measures of disease activity ; known-groups validity , as indicated by differences in WPAI scores between patients with active and inactive disease ; ability ( sensitivity ) to detect change , as indicated by substantial improvement in scores for patients who achieve remission , accompanied by substantial worsening of scores for patients who relapse ; and , responsiveness to treatment , with improvements in scores following treatments that reduce disease activity .
Patients with ulcerative colitis , a type of inflammatory bowel disease , report negative impacts of disease symptoms on work-related outcomes , including absenteeism and presenteeism .
As a way to better underst and the impact of this disease and its treatment on work-related outcomes , the current review examines the use of the Work Productivity and Activity Impairment Question naire ( WPAI ) , a patient-reported outcomes measure of absenteeism , presenteeism , and impairment in other activities , in studies of patients with ulcerative colitis .
This review assesses the measurement properties of the WPAI in this patient population : its reliability , construct validity , ability to detect change , and responsiveness to effective treatments .