“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .
[The effect of Xuezhikang on ventricular diastolic function in hypertension].
OBJECTIVE To investigate whether statins have effect on diastolic function of both left and right ventricles in hypertensive patients . METHODS This is a r and omized , mono-blind , placebo-controlled study . 120 systemic hypertensive ( HT ) patients with normal or slightly elevated cholesterol were r and omized to placebo or Xuezhikang ( 1200 mg/d ) for 24 weeks . Extended-release nifedipine was administrated to the HT patients . 30 healthy volunteers served as controls . Plasma were obtained at baseline and 24 weeks after Xuezhikang therapy .  Cholesterol and carboxy-terminal peptide of procollagen type I ( PIP ) were measured . Early diastolic velocity ( Em ) and late diastolic velocity ( Am ) were obtained from right atrioventricular ring and left atrioventricular ring with pulsed wave tissue Doppler imaging . RESULTS The levels of plasma PIP were higher in HT patients . After 24 weeks , the levels of plasma LDL-C , TC and PIP were significantly lower in Xuezhikang group than those in placebo group ; Systolic and diastolic pressure were decreased both in placebo group and Xuezhikang group meanwhile pulse pressure was decreased and Em/Am ratio at left atrioventricular ring was higher in Xuezhikang group as compared with those in placebo group . CONCLUSION In systemic hypertensive patients , Xuezhikang exerts a beneficial effect on diastolic function of left ventricule via controlling blood pressure , lowering blood lipid and inhibiting myocardial fibrosis
“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .