There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .
Comparison of a high-carbohydrate diet with a high-monounsaturated-fat diet in patients with non-insulin-dependent diabetes mellitus.
We compared a high-carbohydrate diet with a high-fat diet ( specifically , a diet high in monounsaturated fatty acids ) for effects on glycemic control and plasma lipoproteins in 10 patients with non-insulin-dependent diabetes mellitus ( NIDDM ) receiving insulin therapy . The patients were r and omly assigned to receive first one diet and then the other , each for 28 days , in a metabolic ward . In the high-carbohydrate diet , 25 percent of the energy was in the form of fat and 60 percent in the form of carbohydrates ( 47 percent of the total energy was in the form of complex carbohydrates ) ; the high-monounsaturated-fat diet was 50 percent fat ( 33 percent of the total energy in the form of monounsaturated fatty acids ) and 35 percent carbohydrates . The two diets had the same amounts of simple carbohydrates and fiber . As compared with the high-carbohydrate diet , the high-monounsaturated-fat diet result ed in lower mean plasma glucose levels and reduced insulin requirements , lower levels of plasma triglycerides and very-low-density lipoprotein cholesterol ( lower by 25 and 35 percent , respectively ; P less than 0.01 ) , and higher levels of high-density lipoprotein ( HDL ) cholesterol ( higher by 13 percent ; P less than 0.005 ) . Levels of total cholesterol and low-density lipoprotein ( LDL ) cholesterol did not differ significantly in patients on the two diets . These preliminary results suggest that partial replacement of complex carbohydrates with monounsaturated fatty acids in the diets of patients with NIDDM does not increase the level of LDL cholesterol and may improve glycemic control and the levels of plasma triglycerides and HDL cholesterol
There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .