There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Effect of docosahexaenoic acid supplementation of lactating women on the fatty acid composition of breast milk lipids and maternal and infant plasma phospholipids.
To determine whether docosahexaenoic acid ( DHA ) supplementation of breast-feeding mothers increases the DHA contents of breast milk and infant plasma phospholipids ( PPs ) , breast-feeding women were r and omly assigned to 3 DHA-supplementation groups ( 170 - 260 mg/d ) or a control group . Group 1 ( n = 6 ) consumed an algae-produced high-DHA triacylglycerol ; group 2 ( n = 6 ) consumed high-DHA eggs ; group 3 ( n = 6 ) consumed a high-DHA , low-eicosapentaenoic acid marine oil ; and group 4 ( n = 6 ) received no supplementation . From before to after supplementation ( 2 and 8 wk postpartum ) , mean ( + /-SD ) maternal PP DHA increased in groups 1 , 2 , and 3 by 1.20 + /- 0.53 , 0.63 + /- 0.82 , and 0.76 + /- 0.35 mol% of fatty acids , respectively ( 23 - 41 % ) , but decreased in group 4 by 0.44 + /- 0.34 mol% ( 15 % ) . Breast-milk DHA of groups 1 , 2 , and 3 increased by 0.21 + /- 0.16 , 0.07 + /- 0.11 , and 0 . 12 + /- 0.07 mol% , respectively ( 32 - 91 % ) but decreased in group 4 by 0.03 + /- 0.04 mol% ( 17 % ) . Mean infant PP DHA in groups 1 , 2 , and 3 increased by 1.63 + /- 0.79 , 0.40 + /- 1.0 , and 0.98 + /- 0.61 mol% , respectively ( 11 - 42 % ) , but only by 0.18 + /- 0.74 mol% ( 5 % ) in group 4 . Correlations between the DHA contents of maternal plasma and breast milk and of milk and infant PPs were significant . Breast-milk and maternal and infant PP 22:5n-6 concentrations were lowest in group 2 . DHA supplementation increases the plasma and breast-milk DHA concentrations of lactating women , result ing in higher PP DHA concentrations in infants
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .