Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .
Protein sparing during treatment of obesity: ketogenic versus nonketogenic very low calorie diet.
Although it is generally agreed that both ketogenic and nonketogenic very low calorie diets promote weight reduction , there is no consensus on a preference of one diet over the other in regard to protein sparing . In the present study , we compared the effects of isocaloric ( 600 kcal/d ) and isonitrogenous ( 8 g nitrogen/d ) ketogenic ( low carbohydrate ) and nonketogenic diets on parameters of protein and amino acid metabolism , in 16 morbidly obese women maintained on these diets for 4 weeks while confined to a metabolic ward .  Cumulative urinary nitrogen excretion ( g/4 wk ) was significantly ( P less than .01 ) greater ( 248 + /- 6 v 207 + /- 12 , mean + /- SEM , n = 8) , and cumulative nitrogen balance significantly ( P less than .02 ) more negative ( -50.4 + /- 4.4 v -18.8 + /- 5.7 ) , during treatment with the ketogenic than with the nonketogenic diet . Plasma leucine concentration ( mumol/L ) was significantly higher ( P less than .05 ) during treatment with the ketogenic than with the nonketogenic diet at day 14 ( 210 + /- 17 v 150 + /- 8) , but not at day 28 ( 174 + /- 9 v 148 + /- 8) . Whole-body rates of leucine oxidation ( mmol/h ) were significantly higher ( P less than .05 ) during treatment with the ketogenic than with the nonketogenic diet at day 14 ( 1.29 + /- 0.20 v 0.92 + /- 0.10 ) and at day 28 ( 1.00 + /- 0.16 v 0.75 + /- 0.10 ) . Conversely , proteolysis , as measured by leucine turnover rate and urinary excretion of 3-methylhistidine , was not significantly different between the diets . ( ABSTRACT TRUNCATED AT 250 WORDS
Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .