1st MTP pain was a prominent feature in people with gout .
Imaging features were common at the 1st MTP including the double contour sign , tophi and erosions .
Conclusions 1st MTP acute arthritis is highly prevalent in people with gout and has a substantial impact on patient-reported pain and disability .
Gout affects the structure and function of the 1st MTP .
Microscopic and imaging studies have demonstrated crystal deposition and joint damage at the 1st MTP in people with gout
Background The aim of this review was to qualitatively synthesis e studies that have investigated characteristics of the  first metatarsophalangeal joint ( 1st MTP )  in gout and to undertake a meta- analysis to estimate the average prevalence of acute 1st MTP arthritis across studies in people with gout .
The effects of commercially available footwear on foot pain and disability in people with gout: a pilot study
Background There is limited evidence on non-pharmacological interventions for gout . The aim of the study was to determine whether a footwear intervention can reduce foot pain and musculoskeletal disability in people with gout . Methods Thirty-six people with gout participated in a prospect i ve intervention study over 8 weeks . Participants selected one of 4 pairs of shoes and thereafter wore the shoes for 8 weeks . The primary outcome was foot pain using a 100 mm visual analogue scale . Secondary outcomes related to function and disability were also analysed . Results The Cardio Zip shoe was selected by 58 % of participants . Compared with baseline , overall scores for all shoes at 8-weeks demonstrated a decrease in foot pain ( p = 0.03 ) , general pain ( p = 0.012 ) , Health Assessment Question naire (HAQ)-II ( p = 0.016 ) and Leeds Foot Impact Scale ( LFIS ) impairment subscale ( p = 0.03 ) . No significant differences were observed in other patient reported outcomes including patient global assessment , LFIS activity subscale , and Lower Limb Task Question naire subscales ( all p > 0.10 ) . We observed significant improvements between baseline measurements using the participants ’ own shoes and the Cardio Zip for foot pain ( p = 0.002 ) , general pain ( p = 0.001 ) , HAQ-II ( p = 0.002 ) and LFIS impairment subscale ( p = 0.004 ) after 8 weeks . The other three shoes did not improve pain or disability . Conclusions Footwear with good cushioning , and motion control may reduce foot pain and disability in people with gout
1st MTP pain was a prominent feature in people with gout .
Imaging features were common at the 1st MTP including the double contour sign , tophi and erosions .
Conclusions 1st MTP acute arthritis is highly prevalent in people with gout and has a substantial impact on patient-reported pain and disability .
Gout affects the structure and function of the 1st MTP .
Microscopic and imaging studies have demonstrated crystal deposition and joint damage at the 1st MTP in people with gout
Background The aim of this review was to qualitatively synthesis e studies that have investigated characteristics of the  first metatarsophalangeal joint ( 1st MTP )  in gout and to undertake a meta- analysis to estimate the average prevalence of acute 1st MTP arthritis across studies in people with gout .