Current evidence on the effects of palm oil consumption on biomarkers of glucose metabolism is poor and limited to only healthy participants .
We conclude that little or no additional benefit will be obtained by replacing palm oil with other oils rich in mono or polyunsaturated fatty acids for changes in glucose metabolism
INTRODUCTION Vegetable oil is an important source of fatty acids , and as palm oil being the highest consumed vegetable oil in many countries , its high saturated fatty acid content has led many concerns on cardiometabolic health .
Dietary fatty acids has also been linked to affect glucose metabolism and insulin sensitivity .
This systematic review is aim ed at critically evaluating the available evidence on the association of palm oil with the biomarkers of glucose metabolism as compared to other vegetable oils .
Overfeeding Polyunsaturated and Saturated Fat Causes Distinct Effects on Liver and Visceral Fat Accumulation in Humans
Excess ectopic fat storage is linked to type 2 diabetes . The importance of dietary fat composition for ectopic fat storage in humans is unknown . We investigated liver fat accumulation and body composition during overfeeding saturated fatty acids ( SFAs ) or polyunsaturated fatty acids ( PUFAs ) . LIPOGAIN was a double-blind , parallel-group , r and omized trial . Thirty-nine young and normal-weight individuals were overfed muffins high in SFAs ( palm oil ) or n-6 PUFAs ( sunflower oil ) for 7 weeks .  Liver fat , visceral adipose tissue ( VAT ) , abdominal subcutaneous adipose tissue ( SAT ) , total adipose tissue , pancreatic fat , and lean tissue were assessed by magnetic resonance imaging . Transcriptomics were performed in SAT . Both groups gained similar weight . SFAs , however , markedly increased liver fat compared with PUFAs and caused a twofold larger increase in VAT than PUFAs . Conversely , PUFAs caused a nearly threefold larger increase in lean tissue than SFAs . Increase in liver fat directly correlated with changes in plasma SFAs and inversely with PUFAs . Genes involved in regulating energy dissipation , insulin resistance , body composition , and fat-cell differentiation in SAT were differentially regulated between diets , and associated with increased PUFAs in SAT . In conclusion , overeating SFAs promotes hepatic and visceral fat storage , whereas excess energy from PUFAs may instead promote lean tissue in healthy humans
Current evidence on the effects of palm oil consumption on biomarkers of glucose metabolism is poor and limited to only healthy participants .
We conclude that little or no additional benefit will be obtained by replacing palm oil with other oils rich in mono or polyunsaturated fatty acids for changes in glucose metabolism
INTRODUCTION Vegetable oil is an important source of fatty acids , and as palm oil being the highest consumed vegetable oil in many countries , its high saturated fatty acid content has led many concerns on cardiometabolic health .
Dietary fatty acids has also been linked to affect glucose metabolism and insulin sensitivity .
This systematic review is aim ed at critically evaluating the available evidence on the association of palm oil with the biomarkers of glucose metabolism as compared to other vegetable oils .