Multifactorial lifestyle interventions aim ed at improving modifiable risk factors in patients with established CHD reduce the risk for fatal cardiovascular events .
Therefore , they may have added value in secondary prevention of CHD
CONTEXT Coronary heart disease ( CHD ) is responsible for about 15 % of all deaths worldwide and is identified as a top priority for decision makers .
Both primary and secondary prevention are considered key strategies in the prevention of CHD .
The aim of this study was to assess the efficacy of nonpharmacologic interventions with multiple lifestyle components in patients with established CHD in comparison to usual care .
Effects of an expanded cardiac rehabilitation programme in patients treated for an acute myocardial infarction or a coronary artery by-pass graft operation
Objective : To investigate the effects of exp and ed cardiac rehabilitation with multifactorial interventions on metabolic and inflammatory markers , exercise performance and on established cardiovascular risk factors . Design : Single-centre prospect i ve r and omized controlled trial . Setting : A university hospital . Subjects : Two hundred and twenty-four patients with an acute myocardial infa rct ion or patients undergoing coronary artery by-pass grafting . Intervention : Patients were r and omized to exp and ed cardiac rehabilitation including stress management , increased physical training , staying at a ' patient hotel ' and cooking sessions , or to usual cardiac rehabilitation Main measures : Biochemical risk markers and exercise performance ; follow-up was one year . Results : There were no significant differences between the two treatment groups in the changes of biochemical risk markers or in exercise performance . Thus , low-density lipoprotein (LDL)-cholesterol levels decreased from 3.00 ( 0.97 ) to 2.54 ( 0.66 ) mmol/L in the intervention group and from 3.20 ( 0.85 ) to 2.54 ( 0.63 ) mmol/L in the control group , fibrinogen levels decreased from 5.30 ( 2.00 ) to 4.25 ( 1.01 ) g/L in the intervention group and from 5.29 ( 1.89 ) to 4.33 ( 0.83 ) g/L in the control group and C-reactive protein ( CRP ) levels decreased from 3.04 ( 2.79 ) to 2.09 ( 2.13 ) mg/L in the intervention group and from 4.01 ( 3.49 ) to 2.39 ( 2.49 ) mg/L in the control group . Total workload ( W ) improved from 118 ( 35 ) to 136 ( 34 ) in the intervention group and from 117 ( 36 ) to 133 ( 39 ) in the control group . Conclusion : There was no further significant benefit in biochemical risk markers or in exercise performance among patients undergoing the exp and ed rehabilitation as compared to the control group which received usual cardiac rehabilitation
Multifactorial lifestyle interventions aim ed at improving modifiable risk factors in patients with established CHD reduce the risk for fatal cardiovascular events .
Therefore , they may have added value in secondary prevention of CHD
CONTEXT Coronary heart disease ( CHD ) is responsible for about 15 % of all deaths worldwide and is identified as a top priority for decision makers .
Both primary and secondary prevention are considered key strategies in the prevention of CHD .
The aim of this study was to assess the efficacy of nonpharmacologic interventions with multiple lifestyle components in patients with established CHD in comparison to usual care .