“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .
[The beneficial effects of xuezhikang on top of extended-released nifedipine in hypertensive patients without severe hyperlipidemia].
OBJECTIVE To investigate whether xuezhikang has additional beneficial effect on lipid peroxidation , myocardial fibrosis , inflammation and blood pressure control in hypertensive patients without sever hyperlipidemia treated with extended-released nifedipine . METHODS This is a r and omized , single-blind , placebo-controlled study , 100 patients with primary hypertension ( HT ) and normal or lightly elevated cholesterol level were r and omized to receive placebo ( n=49 ) or xuezhikang ( 1200 mg/d , n=51 ) for 24 weeks on top of extended-released nifedipine ( 20 mg , bid ) , 30 healthy volunteers served as controls . Plasma was obtained at baseline and 24 weeks after therapy . Lipids , C-reactive protein ( CRP ) , malondialdehyde ( MDA ) , superoxide dismutase photo-inhibition rate ( SOD-PR ) and type I collagen carboxypropeptide ( PIP ) were measured . RESULTS Normal blood pressure ( < 140/90 mm Hg ) was found in 49 out of 51 xuezhikang treated patients and in 40 out of 49 placebo treated patients ( P<0.01 ) after 24 weeks therapy . Plasma CRP , MDA , SOD-PR and PIP were significantly higher in HT patients than those in normal controls . Plasma CRP , MDA , PIP and SOD-PR were significantly decreased in xuezhikang group while remained unchanged in placebo group after 24 weeks treatment . CONCLUSION In patients with primary hypertension without severe hyperlipidemia treated with nifedipine , xuezhikang treatment exerts additional beneficial effects including better blood pressure control , endothelial function improvement , lipid oxidation loading attenuation and anti-inflammation
“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .