The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .
Antishivering effects of two different doses of intrathecal meperidine in caesarean section: a prospective randomised blinded study
Background and objective Shivering causes various adverse disturbances and interferes with monitoring . The optimal dose of intrathecal meperidine to prevent shivering without producing other side-effects remains unknown . This prospect i ve r and omised double-blinded study was conducted to compare the antishivering effects of two different doses of intrathecal meperidine . Methods Seventy two parturients , scheduled for elective caesarean section under spinal anaesthesia , were enrolled in three different groups . Spinal anaesthesia consisted of bupivacaine 0.5 % ( 10 mg ) for the control group ( M0 ) , and the same dose of bupivacaine with meperidine 12.5 or 25 mg for the experimental groups ( M1 , M2 ) . Blood pressure , heart rate , skin and core temperatures , sensory level , capnometry , pulse oximetry , Apgar scores , shivering intensity and intrathecal opioid-related side-effects were evaluated and recorded by a blinded observer . Data were analysed using analysis of variance , χ2 test , Kruskal – Wallis H-test and Mann – Whitney U-test . A P value less than 0.05 was considered to be significant . Results Shivering was more intense in group M0 than in groups M1 and M2 with P values of 0.003 and less than 0.001 , respectively . The intensity of shivering was comparable in groups M1 and M2 . As regards the incidence of significant shivering , it was found to be highest in M0 ( 4/24 ≈16.7 % ) in comparison with M1 ( 0/24 ) and M2 ( 0/24 ) ( P = 0.03 ) . Nausea and vomiting occurred more frequently with higher doses of meperidine ( P < 0.001 and P = 0.003 , respectively ) . Other complications were comparable . Conclusion The use of intrathecal meperidine for caesarean section during spinal anaesthesia for the prevention of shivering can not be recommended as its use is associated with increased incidence of nausea and vomiting
The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .