Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
Lipid responses of hypercholesterolemic men to oat-bran and wheat-bran intake.
The hypocholesterolemic effects of oat bran ( OB ) have been recently challenged . To carefully document the hypocholesterolemic effects of OB , 20 hypercholesterolemic men admitted to a metabolic ward were r and omly allocated to either OB or wheat bran ( WB ) for 21 d after a 7-d control-diet period . Control and treatment diets were design ed to be identical in energy content and nutrients , differing only in the amount of soluble fiber . After 21 d , OB significantly decreased total cholesterol by 12.8 % ( P less than 0.001 ) , low-density-lipoprotein cholesterol by 12.1 % ( P less than 0.004 ) , and apolipoprotein B-100 by 13.7 % ( P less than 0.001 ) whereas WB had no significant effect . High-density-lipoprotein cholesterol and apolipoprotein A-I did not change significantly in either group . Serum triglycerides decreased by 10 % in both groups but the decrease was only significant ( P less than 0.04 ) in WB subjects . OB but not WB significantly reduced total cholesterol and other atherogenic lipoprotein fractions independent of other dietary changes
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .