Conclusion The prevalence of sarcopenia depends mostly on the diagnostic cut-off points of different criteria .
Preoperative sarcopenia is a risk factor for both long-term and short-term outcomes
Background The impact of sarcopenia on the outcome of gastrointestinal ( GI ) oncological patients is still controversial .
We aim to discuss the prevalence of sarcopenia and its relation to the oncological outcome .
Prognostic Value of Computed Tomography: Measured Parameters of Body Composition in Primary Operable Gastrointestinal Cancers
Background Previous reports suggest that body composition parameters can be used to predict outcomes for patients with gastrointestinal ( GI ) cancers . However , evidence for an association with long-term survival is conflicting , with much of the data derived from patients with advanced disease . This study examined the effect of body composition on survival in primary operable GI cancer . Methods Patients with resectable adenocarcinoma of the GI tract ( esophagus , stomach , colon , rectum ) between 2006 and 2014 were identified from a prospect i ve data base .  Computed tomography ( CT ) scans were analyzed using a transverse section at L3 to calculate sex-specific body composition indices for skeletal muscle , visceral fat , and subcutaneous fat . Kaplan – Meier and log-rank analysis were used to compare unadjusted survival . Multivariate survival analyses were performed using a proportional hazards model . Results The study enrolled 447 patients ( 191 woman and 256 men ) with esophagogastric ( OG ) ( n = 108 ) and colorectal ( CR ) ( n = 339 ) cancer .  Body composition did not predict survival for the OG cancer patients . Among the CR cancer patients , survival was shorter for those with sarcopenia ( p = 0.017 ) or low levels of subcutaneous fat ( p = 0.005 ) . Older age ( p = 0.046 ) and neutrophilia ( p = 0.013 ) were associated with sarcopenia in patients with CR . Tumor stage ( p = 0.033 ) , neutrophil count ( p = 0.011 ) , and hypoalbuminemia ( p = 0.023 ) were associated with sarcopenia in OG cancer patients . In the multivariate analysis , no single measure of body composition was an independent predictor of reduced survival . ConclusionS arcopenia and reduced subcutaneous adiposity are associated with reduced survival for patients with primary operable CR cancer . However , in this study , no parameter of body composition was an independent prognostic marker when considered with age , tumor stage , and systemic inflammation
Conclusion The prevalence of sarcopenia depends mostly on the diagnostic cut-off points of different criteria .
Preoperative sarcopenia is a risk factor for both long-term and short-term outcomes
Background The impact of sarcopenia on the outcome of gastrointestinal ( GI ) oncological patients is still controversial .
We aim to discuss the prevalence of sarcopenia and its relation to the oncological outcome .