Conclusion This study suggests that the probiotics supplementation could potentially reduce the weight gain and improve some of the associated metabolic parameters , which may become an effective strategy for the prevention and treatment of obesity in adult individuals
Background The prevalence of overweight/obesity in adults is raised to 39 % , which is nearly tripled more than 1975 .
The alteration of the gut microbiome has been widely accepted as one of the main causal factors .
To find an effective strategy for the prevention and treatment of overweight/obesity , a systematic review and meta- analysis were design ed .
Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial.
Consumption of fermented milk ( FM ) containing a probiotic , Lactobacillus gasseri SBT2055 ( LG2055 ) , previously showed a reduction in abdominal adiposity in a r and omised controlled trial ( RCT ) using FM with 10(8 ) colony-forming units ( cfu ) of LG2055/g . However , whether the effectiveness is observed at lower concentrations , the recommended minimum or intermediate levels of probiotics ( 10(6 ) or 10(7 ) cfu/g , respectively ) , remains to be examined . A multi-centre , double-blind , parallel-group RCT was conducted using 210 healthy Japanese adults with large visceral fat areas ( 80·2 - 187·8 cm(2 ) ) . They were balanced for their baseline characteristics and r and omly assigned to three groups receiving FM containing 10(7 ) , 10(6 ) or 0 ( control ) cfu LG2055/g of FM , and were asked to consume 200 g FM/d for 12 weeks . Abdominal visceral fat areas , which were determined by computed tomography , at week 12 , changed from baseline by an average of -8·5 % ( 95 % CI -11·9 , -5·1 ; P < 0·01 ) in the 10(7 ) dose group , and by -8·2 % ( 95 % CI -10·8 , -5·7 ; P < 0·01 ) in the 10(6 ) dose group . Other measures including BMI , waist and hip circumferences , and body fat mass were also significantly decreased from baseline at week 12 in both groups ; interestingly , the cessation of taking FM for 4 weeks attenuated these effects . In the control group , none of these parameters significantly decreased from baseline . These findings demonstrate that consumption of LG2055 at doses as low as the order of 10(8 ) cfu/d exhibited a significant lowering effect on abdominal adiposity , and suggest that constant consumption might be needed to maintain the effect
Conclusion This study suggests that the probiotics supplementation could potentially reduce the weight gain and improve some of the associated metabolic parameters , which may become an effective strategy for the prevention and treatment of obesity in adult individuals
Background The prevalence of overweight/obesity in adults is raised to 39 % , which is nearly tripled more than 1975 .
The alteration of the gut microbiome has been widely accepted as one of the main causal factors .
To find an effective strategy for the prevention and treatment of overweight/obesity , a systematic review and meta- analysis were design ed .