Studies have also shown a significant reduction in systolic and diastolic blood pressures after Zinc supplementation .
This first comprehensive systematic review and meta- analysis on the effects of Zinc supplementation in patients with diabetes demonstrates that Zinc supplementation  has beneficial effects on glycaemic control and promotes healthy lipid parameters .
The number of people with diabetes and pre-diabetes are exponentially increasing .
Studies on humans have shown the beneficial effects of Zinc supplementation in patients with diabetes .
The present study aims to systematic ally evaluate the literature and meta-analyze the effects of Zinc supplementation on diabetes .
Oral zinc therapy in diabetic neuropathy.
The present double blind r and omized study was conducted on 50 subjects ; 20 age and sex matched healthy controls ( Group -- I ) ; 15 patients of diabetes mellitus with neuropathy who received placebo for 6 weeks ( Group -- IIA ) ; and 15 patients of diabetes mellitus with neuropathy who were given supplemental zinc sulphate ( 660 mg ) for 6 weeks ( Group -- IIB ) .  Serum zinc level , fasting blood sugar ( FBS ) and post pr and ial blood sugar ( PPBS ) levels and motor nerve conduction velocity ( MNCV ) were estimated on day 0 and after 6 weeks in all subjects . Serum zinc levels were significantly low ( p < 0.001 ) in group IIA and IIB as compared to healthy controls ( Group -- I ) at baseline . After 6 weeks the change in pre and post therapy values of FBS , PPBS and MNCV ( median and common peroneal nerve ) were highly significant ( P = < 0.001 ) for group IIB alone with insignificant change ( P = > 0.05 ) in group IIA . No improvement ( P = > 0.05 ) in autonomic dysfunction was observed in either groups . Therefore , oral zinc supplementation helps in achieving better glycemic control and improvement in severity of peripheral neuropathy as assessed by MNCV
Studies have also shown a significant reduction in systolic and diastolic blood pressures after Zinc supplementation .
This first comprehensive systematic review and meta- analysis on the effects of Zinc supplementation in patients with diabetes demonstrates that Zinc supplementation  has beneficial effects on glycaemic control and promotes healthy lipid parameters .
The number of people with diabetes and pre-diabetes are exponentially increasing .
Studies on humans have shown the beneficial effects of Zinc supplementation in patients with diabetes .
The present study aims to systematic ally evaluate the literature and meta-analyze the effects of Zinc supplementation on diabetes .