This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
The Effects of Aerobic Exercises and 25(OH) D Supplementation on GLP1 and DPP4 Level in Type II Diabetic Patients
Background : The purpose of this study was to investigate the effects of an 8-week aerobic exercise and supplementation of 25(OH)D3 on GLP1 and DDP4 levels in men with type II diabetes . Methods : In this semiexperimental research , among 40–60-year-old men with type II diabetes who were referred to the diabetic center of Isabn-E Maryam hospital in Isfahan ; of whom , 48 patients were voluntarily accepted and then were r and omly divided into 4 groups : aerobic exercise group , aerobic exercise with 25(OH ) D supplement group , 25(OH ) D supplement group , and the control group . An aerobic exercise program was conducted for 8 weeks ( 3 sessions/week , each session 60 to75 min with 60–80 % HRmax ) . The supplement user group received 50,000 units of oral Vitamin D once weekly for 8 weeks . The GLP1 , DPP4 , and 25(OH ) D levels were measured before and after the intervention . At last , the data were statistically analyzed using the ANCOVA and post hoc test of least significant difference . Results : The results of ANCOVA showed a significant difference between the GLP1 and DPP4 levels in aerobic exercise with control group while these changes were not statistically significant between the 25(OH ) D supplement group with control group ( P < 0.05 ) . Conclusions : Aerobic exercises have result ed an increase in GLP1 level and a decrease in DPP4 level . However , consumption of Vitamin D supplement alone did not cause any changes in GLP1 and DPP4 levels but led to an increase in 25-hydroxy Vitamin D level
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .