Attempts to prevent dysgeusia through the prophylactic use of zinc sulfate or amifostine have been of limited benefit .
Nutritional counseling may be helpful to some patients in minimizing the symptoms of dysgeusia .
Conclusions Dysgeusia is a common oral side effect of cancer therapy ( radiotherapy , chemotherapy , or combined modality therapy ) and often impacts negatively on quality of life .
From the current literature , there does not appear to be a predictable way of preventing or treating dysgeusia
Purpose The purpose was to review relevant scientific papers written since 1989 which focused on the prevalence and management of  dysgeusia as an oral side effect of cancer treatment .
Symptom profile of nasopharyngeal cancer patients during radiation therapy.
PURPOSE This prospect i ve , longitudinal study was aim ed to describe the prevalence , severity , and pattern of symptoms over the course of radiation therapy in persons with nasopharyngeal carcinoma and to explore symptom severity by treatment modality . DESCRIPTION OF STUDY Thirty-seven patients completed this study , and 46 % received chemotherapy before radiation therapy .  A self-reported radiation symptom checklist and an objective mucositis assessment tool were used weekly to document oropharyngeal , skin , nose or ear , or more general side effects , and mucositis . RESULTS Oropharyngeal problems were the most severe complaints during radiation therapy . All patients experienced dry mouth , taste change , difficulty in swallowing , difficulty in opening their mouths , hoarseness , sore throat , and observable mucositis . Most reported moderate-to-severe dry mouth , difficulty in swallowing , and sore throat from weeks 3 through 7 . Skin problems were not prominent until week 4 . Patients also lost an average of 3.9 kg during the therapy . Sequential chemotherapy and radiation therapy was associated with more severe oropharyngeal problems than radiation therapy alone , but no significant differences in other problems were found . CLINICAL IMPLICATION S Despite recognition of the oropharyngeal side effects associated with irradiation , effective management protocol s for such symptoms have not been implemented in the studied institution . The frequency and intensity of the symptoms reported indicate an urgent need for increased vigilance about radiation-related side effects and pain management . As well , patient education about expected side effects may help mitigate the anxiety that patients experience when these symptoms occur
Attempts to prevent dysgeusia through the prophylactic use of zinc sulfate or amifostine have been of limited benefit .
Nutritional counseling may be helpful to some patients in minimizing the symptoms of dysgeusia .
Conclusions Dysgeusia is a common oral side effect of cancer therapy ( radiotherapy , chemotherapy , or combined modality therapy ) and often impacts negatively on quality of life .
From the current literature , there does not appear to be a predictable way of preventing or treating dysgeusia
Purpose The purpose was to review relevant scientific papers written since 1989 which focused on the prevalence and management of  dysgeusia as an oral side effect of cancer treatment .