Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .
More acidic dietary acid-base load is associated with reduced calcaneal broadband ultrasound attenuation in women but not in men: results from the EPIC-Norfolk cohort study.
BACKGROUND Dietary patterns that promote mild metabolic acidosis may have a negative effect on  bone density .  OBJECTIVE We investigated the relation between a measure of  dietary acid-base load , potential renal acid load ( PRAL ) , and calcaneal broadb and ultrasound attenuation ( BUA ) after adjustment for confounders and also compared the results with different estimates of acid-base load . DESIGN A cross-sectional study was conducted in 14 563 men and women aged 42 - 82 y living in Norfolk , United Kingdom , in which measures of calcaneal BUA  and dietary PRAL were estimated by using the European Prospect i ve Investigation into Cancer and Nutrition Norfolk ( EPIC-Norfolk ) food-frequency question naire . RESULTS A more acidic dietary intake ( high PRAL ) was significantly associated with lower calcaneal BUA in women but not in men ; there was a difference of approximately 2 % in BUA between the highest and lowest quintiles of PRAL , independent of age , body mass index , smoking habit , physical activity , diagnosed osteoporosis , and history of fracture , and ( in women ) hormone replacement therapy . No relation was observed between history of fracture or incident fracture and PRAL . Those with the greatest PRAL had higher intakes of meat , fish , eggs , and cereal and cereal products and lower intakes of fruit and vegetables , tea , and coffee . CONCLUSION PRAL was inversely associated with bone ultrasound measures in women , but the magnitude of the association was relatively small compared with other known risk factors . Further longitudinal studies are required to establish whether , in the long term , these small effects are important in overall fracture risk in population
Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .