In most respects , all membranes and enamel matrix derivative ( EMD ) delivered better outcomes , in the range of 1 to 2 mm , than open flap debridement .
The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level ( CAL ) gain than any open flap configuration .
GTR was confirmed to be superior to open flap debridement
In a 1998 review article , Laurell and colleagues performed a meta- analysis of relevant guided tissue regeneration ( GTR ) articles over the previous 20 years ( 1 ) .
The purpose of the present research was to exp and on that work , particularly search ing for trends discriminating between bioabsorbable and non-bioabsorbable barriers , as well as the use of enamel matrix derivative , with respect to interproximal bony defects .
A controlled re-entry study on the effectiveness of bovine porous bone mineral used in combination with a collagen membrane of porcine origin in the treatment of intrabony defects in humans.
AIM The purpose of this study was to evaluate the clinical effectiveness of a bovine porous bone mineral used in combination with a porcine derived collagen membrane as a barrier in promoting periodontal regeneration in intrabony defects in humans . MATERIAL AND METHODS The study employed a split-mouth design . 22 paired intrabony defects were treated and surgically re-entered 6 months after treatment . Experimental sites were grafted with bovine porous bone mineral and received a collagen membrane for guided tissue regeneration . Control sites were treated with an open flap debridement . RESULTS Preoperative pocket depths , attachment levels and trans-operative bone measurements were similar for control and experimental sites . Post surgical measurements revealed a significantly greater reduction in pocket depth ( differences of 1.89 + /- 0.31 mm on buccal 0.88 + /- 0.27 mm on lingual measurements ) and more gain in clinical attachment ( differences of 1.51 + /- 0.33 mm on buccal and 1.50 + /- 0.35 mm on lingual measurements ) in experimental sites . Surgical reentry of the treated defects revealed a significantly greater amount of defect fill in favor of experimental sites ( differences of 2.67 + /- 0.91 mm on buccal and 2.54 + /- 0.87 mm on lingual measurements ) . CONCLUSIONS The results of this study indicate that clinical resolution of intrabony defects can be achieved using a combination of bovine porous bone mineral and an absorbable , porcine derived collagen membrane when employing a technique based on the principles of guided tissue regeneration . The nature of the attachment between the newly regenerated tissue and the root surfaces needs to be evaluated histologically to confirm the presence of new attachment
In most respects , all membranes and enamel matrix derivative ( EMD ) delivered better outcomes , in the range of 1 to 2 mm , than open flap debridement .
The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level ( CAL ) gain than any open flap configuration .
GTR was confirmed to be superior to open flap debridement
In a 1998 review article , Laurell and colleagues performed a meta- analysis of relevant guided tissue regeneration ( GTR ) articles over the previous 20 years ( 1 ) .
The purpose of the present research was to exp and on that work , particularly search ing for trends discriminating between bioabsorbable and non-bioabsorbable barriers , as well as the use of enamel matrix derivative , with respect to interproximal bony defects .