This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .
"Patient demand" postoperative analgesia with buprenorphine. Comparison between sublingual and i.m. administration.
A r and omized , double-blind , placebo-controlled study of buprenorphine was carried out in 20 patients after cholecystectomy . The drug was given on " patient dem and " either i.m . ( 0.15 mg ) or sublingually ( 0.2 mg ) with a minimum dose interval of 30 min . Over the 24-h study period the mean dem and by the sublingual route was 0.8 mg ( range 0.6 - 1.2 mg ) and by the i.m . route 0.66 mg ( range 0.45 - 0.9 mg ) . Pain relief , by visual analogue scales and grading , was similar . Plasma buprenorphine concentrations varied more after sublingual administration . Either route was effective for the treatment of pain when administered by " patient dem and "
This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .