A clinical ly relevant but not statistically significant reduction in triglycerides was found .
No impact on HDL-C levels was found .
Patients ' adherence to pharmacotherapeutic regimens and quality of life were considered possibly not sensitive and possibly sensitive to pharmacist interventions , respectively .
Total cholesterol is sensitive to pharmacist interventions , while LDL-C and triglyceride levels are possibly sensitive to those interventions .
BACKGROUND Hyperlipidemia increases the risk of cardiovascular diseases , and control is pivotal for preventing disease complications .
Multidisciplinary interventions , including those performed by pharmacists , are important for improving patients ' outcomes .
OBJECTIVE To quantify the impact of pharmacist interventions in enhancing patients ' outcomes .
Effect of intervention through a pharmaceutical care program on patient adherence with prescribed once-daily atorvastatin.
AIMS Correct execution of prescribed dosing regimen(s ) is essential for patients to benefit from lipid lowering treatments . The objective of this study was to estimate the effect of a pharmaceutical care program on the adherence of once-daily atorvastatin treatment in patients with elevated cholesterol levels . METHODS In both linguistic regions of Belgium , two districts were r and omized between usual care and a supportive intervention program . Eligible patients included hyperlipemic subjects taking atorvastatin for at least 3 months . ' Adherence ' was defined as the proportion of days during which the electronic device record showed that the patient had taken the daily dose . ' Persistence ' quantifies how long the treatment is executed . RESULTS A total of 392 patients from 35 pharmacies were included in the intent-to-treat ( ITT ) analysis of the data ( 194 patients received intervention and 198 in the control group ) . The intervention result ed in a 6.5 % increase in post-baseline adherence ( p < 0.001 ) mainly driven by a 13 % increase in persistence at 1 year ( p = 0.002 ) . CONCLUSION A supportive pharmaceutical care program consisting of review by patient and pharmacist of each patient 's electronically compiled dosing history , plus educational reminders , improves patient adherence to the once-daily atorvastatin dosing regimen , mainly by extending persistence
A clinical ly relevant but not statistically significant reduction in triglycerides was found .
No impact on HDL-C levels was found .
Patients ' adherence to pharmacotherapeutic regimens and quality of life were considered possibly not sensitive and possibly sensitive to pharmacist interventions , respectively .
Total cholesterol is sensitive to pharmacist interventions , while LDL-C and triglyceride levels are possibly sensitive to those interventions .
BACKGROUND Hyperlipidemia increases the risk of cardiovascular diseases , and control is pivotal for preventing disease complications .
Multidisciplinary interventions , including those performed by pharmacists , are important for improving patients ' outcomes .
OBJECTIVE To quantify the impact of pharmacist interventions in enhancing patients ' outcomes .