This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .
Propofol Maintenance to Reduce Postoperative Emesis in Thyroidectomy Patients: A Group Sequential Comparison with Isoflurane/Nitrous Oxide
The clinical benefit of propofol anaesthesia in the prevention of postoperative nausea and vomiting ( PONV ) is still being eluci date d despite many studies to date . In this study 64 adult female patients scheduled for thyroidectomy received , in a r and omized double-blind fashion , propofol with air or isoflurane with nitrous oxide for maintenance of anaesthesia . The primary response variable was the presence or absence of vomiting in the first six hours . A group sequential design was used to allow interim analysis . After 64 patients , the fourth analysis showed that fewer patients receiving propofol  vomited or required an anti-emetic during the first six hours ( P<0.05 ) . There was no significant difference detected in the 6 to 24 hour interval . In this group of female patients , total intravenous anaesthesia ( TIVA ) with propofol is associated with an early reduction in early postoperative vomiting compared with st and ard inhalational techniques . This reduction in vomiting does not appear to persist beyond the first six hours
This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .