In conclusion , bariatric surgery is associated with a reduction in specific adipokines including leptin , chemerin , and PAI-1 , whereas adiponectin is raised , adaptations that could be indicative of improved fat mass and function
Different adipokines secreted from adipose tissue , exert a range of physiological effects .
The aim of present systematic review and meta- analysis was to critically investigate the consequence of  bariatric surgery on circulating adipokines , that is , adiponectin , leptin , visfatin , resistin , plasminogen activator inhibitor , and chemerin .
Visceral Adipose Tissue Loss and Insulin Resistance 6 Months after Laparoscopic Gastric Banding Surgery: A Preliminary Study
Background Increased  visceral adipose tissue ( VAT ) is thought to be a risk factor for cardiovascular and metabolic diseases . There are only limited data on whether VAT loss after laparoscopic gastric b and ing surgery ( LGBS ) is related to risk factor reduction . This study determined whether improvements in risk markers , in particular insulin resistance , were related to  VAT reduction at 6 months after LGBS ( T2 ) . Methods Thirty-four LGBS patients and 17 normal weight controls underwent initial and T2 testing . Fasting venous blood sample s were taken to evaluate glucose , insulin , hemoglobin A1c , lipids , C-reactive protein ( CRP ) , and hormone profiles . Insulin resistance was estimated using the homeostasis model assessment ( HOMA ) index .  VAT  was measured using CT techniques . Data were analyzed using repeated measures ANOVA and regression analysis . Results Results at T2 showed that patients had significant improvements in body composition , HOMA , and hemoglobin A1c . There were also reductions in plasma renin activity and leptin , and increases in ghrelin and GLP-1 . Reductions in VAT were significantly correlated with reductions in insulin , HOMA , and glucose . While high density lipoprotein cholesterol , triglycerides , CRP , and the apolipoprotein A1/B ratio were also improved , VAT reduction was significantly correlated only with an increased apolipoprotein A1/B ratio . Conclusion These data indicate that 6 months after LGBS there were significant improvements in many cardiovascular and metabolic risk markers . However , VAT reduction was most strongly associated with reductions in insulin resistance . Body weight loss was not associated with markers of improved insulin sensitivity
In conclusion , bariatric surgery is associated with a reduction in specific adipokines including leptin , chemerin , and PAI-1 , whereas adiponectin is raised , adaptations that could be indicative of improved fat mass and function
Different adipokines secreted from adipose tissue , exert a range of physiological effects .
The aim of present systematic review and meta- analysis was to critically investigate the consequence of  bariatric surgery on circulating adipokines , that is , adiponectin , leptin , visfatin , resistin , plasminogen activator inhibitor , and chemerin .