Despite limitations in these data , our NMA findings are in line with existing evidence on the metabolic effects of fat and support current recommendations to replace high saturated-fat food with unsaturated oils
The aim of this network meta- analysis ( NMA ) is to compare the effects of different oils/solid fats on blood lipids .
Virgin olive oil reduces blood pressure in hypertensive elderly subjects.
BACKGROUND & AIMS Hypertension is one of the most important risk factors for coronary heart disease . Recent studies have pointed out the possibility that virgin olive oil ( VOO ) may lower blood pressure in hypertensive ( HT ) subjects . However , until the date there is scarce information regarding elderly people . The present study was design ed to assess the effect of dietary VOO on blood pressure in medically treated hypertensive elderly patients . METHODS 31 medically treated HT elderly patients and 31 normotensive ( NT ) elderly volunteers participated in a r and omized sequential dietary intervention . Subjects consumed diets enriched in sunflower oil ( SO ) or VOO for 4 weeks each with a 4-week washout period between them . RESULTS VOO reduced total and LDL-cholesterol in NT but not in HT ( P < 0.01 ) and the concentrations were lower than in the group consuming SO . In contrast , no significant differences were found in the levels of tocopherols among the groups studied . Iron-induced oxidation of LDL result ed in a complete loss of monoacylglycerols ( MG ) and diacylglycerols ( DG ) and a reduction in triacylglycerols ( TG ) ( 60 - 80 % ) , which was found to be greater in HT ( P < 0.01 ) with no effect of diet . VOO consumption normalized systolic pressure in the HT group ( 136 + /- 10 mmHg ) compared to SO ( 150 + /- 8 mmHg ) . CONCLUSION Dietary VOO proved to be helpful in reducing the systolic pressure of treated HT elderly subjects . However , a greater resistance to the lowering effect of VOO of total and LDL-cholesterol and a greater susceptibility to TG oxidation was detected in these patients
Despite limitations in these data , our NMA findings are in line with existing evidence on the metabolic effects of fat and support current recommendations to replace high saturated-fat food with unsaturated oils
The aim of this network meta- analysis ( NMA ) is to compare the effects of different oils/solid fats on blood lipids .