Multiple secondary data analyses of TORDIA have identified important predictors of treatment response and relapse .
To up date a comparative effectiveness review ( 1980–2011 ) of treatments for adolescents whose depressive episode or disorder ( MDE/MDD ) did not respond to one or more trials of SSRI antidepressants .
A Randomized Controlled Effectiveness Trial of Acceptance and Commitment Therapy and Cognitive Therapy for Anxiety and Depression
Acceptance and commitment therapy ( ACT ) has a small but growing data base of support . One hundred and one heterogeneous out patients reporting moderate to severe levels of anxiety or depression were r and omly assigned to traditional cognitive therapy ( CT ) or to ACT . To maximize external validity , the authors utilized very minimal exclusion criteria . Participants receiving CT and ACT  evidence d large , equivalent improvements in depression , anxiety , functioning difficulties , quality of life , life satisfaction , and clinician-rated functioning . Whereas improvements were equivalent across the two groups , the mechanisms of action appeared to differ . Changes in “ observing ” and “ describing ” one 's experiences appeared to mediate outcomes for the CT group relative to the ACT group , whereas “ experiential avoidance , ” “ acting with awareness , ” and “ acceptance ” mediated outcomes for the ACT group . Overall , the results suggest that ACT is a viable and disseminable treatment , the effectiveness of which appears equivalent to that of CT , even as its mechanisms appear to be distinct
Multiple secondary data analyses of TORDIA have identified important predictors of treatment response and relapse .
To up date a comparative effectiveness review ( 1980–2011 ) of treatments for adolescents whose depressive episode or disorder ( MDE/MDD ) did not respond to one or more trials of SSRI antidepressants .