We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .
Effect of omega-3 fatty acids on cardiovascular risk factors in patients with type 2 diabetes mellitus and hypertriglyceridemia: an open study.
BACKGROUND AND OBJECTIVES Epidemiological and interventional studies suggest that a high dietary intake of n-3 polyunsaturated fatty acids may confer a protective effect against atherosclerotic disease and reduce serum triglycerides levels . The aim of our study was to investigate the effectivity on triglyceride levels and inflammatory markers of a concentrated of n-3 fatty acids in patients with type 2 diabetes mellitus and hypertriglyceridaemia . SUBJECTS A total of 30 patients ( 16 males and 14 females ) with diabetes mellitus type 2 and hypertriglyceridemia ( > 200 mg/dl ) were included in the study . Patients received two capsules of eicosapentaenoic 465 mg and docosahexanoic 375 mg daily for 12 weeks . RESULTS Triglycerides levels and non HDL-cholesterol decreased ( 326 + /- 113.5 vs. 216.4 + /- 57 mg/dl ; p < 0.05 ) and ( 103.87 + /- 44 vs. 89.6 + /- 14 mg/dl ; p < 0.05 ) , respectively . HDL-cholesterol levels increased ( 39.6 + /- 10.7 vs. 46.4 + /- 8.7 mg/dl ; p < 0.05 ) . C reactive protein decreased ( 5.98 + /- 3.9 vs. 3.9 + /- 1.6 mg/dl ; p < 0.05 ) and TNF-alpha levels decreased ( 16.24 + /- 5.5 vs. 13.3 + /- 5.8 pg/dl ; p < 0.05 ) , without significant changes in IL-6 levels . In conclusion , an n-3 polyunsaturated intervention improved lipid profile and inflammatory markers in patients with diabetes mellitus type 2 and hypertriglyceridaemia
We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .