Conclusions MTA cements have a higher success rate , with a lower inflammatory response and a more predictable hard dentin barrier formation  than calcium hydroxide cements .
However , there were no differences , in these parameters , when MTA cement was compared with tricalcium silicate cements .
Dental adhesives systems showed the lowest success rates
Introduction Direct pulp capping therapies use bio material s to protect exposed tissues , inducing repair through the production of a mineralized barrier .
The purpose of this study was to compare the effectiveness of bio material s and techniques by means of a systematic review and meta‐ analysis .
Dental pulp capping: effect of Emdogain Gel on experimentally exposed human pulps.
AIM To investigate the effect of Emdogain Gel ( Biora AB , Malmo , Sweden ) , consisting of a enamel matrix derivative ( EMD ) in a propylene glycol alginate ( PGA ) vehicle , on experimentally exposed human pulps and to register postoperative symptoms . METHODOLOGY Nine pairs of contralateral premolars scheduled for extraction on orthodontic indications were included . Following a superficial pulp amputation performed with a small ( 016 ) diamond bur , either EMDgel or a mix of calcium hydroxide and sterile saline was placed at r and om in contact with the pulp wound . The subjects made records of symptoms and were also interviewed about pain/discomfort by a blinded examiner . After 12 weeks the teeth were extracted , prepared and subjected to light microscopic examination in which the inflammation and newly formed hard tissue in the pulp were analysed . Immunohistochemistry was performed using affinity-purified rabbit anti-EMD polyclonal antibodies . RESULTS Postoperative symptoms were less frequent in the EMDgel-treated than in the calcium hydroxide-treated teeth , especially during the first six weeks . In the EMDgel-treated teeth , new tissue partly filled the space initially occupied by the gel and hard tissue was formed alongside the exposed dentine surfaces and in patches in the adjacent pulp tissue .  EMD  was detected in the areas where new hard tissue had been formed . The wound area of the EMDgel-treated teeth exhibited inflammation in the majority of the teeth whereas less inflammation was seen in the calcium hydroxide-treated teeth where the hard tissue was formed as a bridge . CONCLUSIONS In the EMDgel-treated teeth , postoperative symptoms were less frequent and the amount and pattern of hard tissue formation were markedly different than in the teeth treated with calcium hydroxide . However , the operative procedure and the formulation with EMD in a PGA vehicle do not seem to be effective for the formation of a hard tissue barrier
Conclusions MTA cements have a higher success rate , with a lower inflammatory response and a more predictable hard dentin barrier formation  than calcium hydroxide cements .
However , there were no differences , in these parameters , when MTA cement was compared with tricalcium silicate cements .
Dental adhesives systems showed the lowest success rates
Introduction Direct pulp capping therapies use bio material s to protect exposed tissues , inducing repair through the production of a mineralized barrier .
The purpose of this study was to compare the effectiveness of bio material s and techniques by means of a systematic review and meta‐ analysis .