AUTHORS ' CONCLUSIONS Feeding with a soy formula can not be recommended for prevention of allergy or food intolerance in infants at high risk of allergy or food intolerance .
BACKGROUND Allergies and food reactions in infants and children are common and may be associated with a variety of foods including adapted cow 's milk formula .
Soy based formulas have been used to treat infants with allergy or food intolerance .
However , it is unclear whether they can help prevent allergy and food intolerance in infants without clinical evidence of allergy or food intolerance .
OBJECTIVES To determine the effect of feeding adapted soy formula compared to human milk , cow 's milk formula or a hydrolysed protein formula on preventing allergy or food intolerance in infants without clinical evidence of allergy or food intolerance .
Soy versus cow's milk in infants with a biparental history of atopic disease: development of atopic disease and immunoglobulins from birth to 4 years of age
Forty‐eight children with a biparental history of atopic disease were followed from birth to 4 years of age . One group was fed soy and the other cow 's milk from weaning to 9 months of age . Two‐thirds of the children developed symptoms of atopic disease with no significant difference between the groups . No difference was found in the serum immunoglobulins ( IgE antibodies , IgA , IgG and IgM ) during the observation period . The soy fed children showed transiently lower levels of IgG antibodies to cow 's milk but higher levels of IgG antibodies to soy protein . Six children showed cow 's milk intolerance and a further five had symptoms possibly related to the use of cow 's milk . Withholding cow 's milk during the first 9 months did not reduce the incidence of symptoms of cow 's milk intolerance from birth to 4 years of age . Thus , no benefit was found from replacing cows ' milk with soy . A prolonged breast feeding seems most rational for infants at risk of developing atopic disease , even if the present study did not show evidence of a prophylactic effect of breast milk against the development of atopic disease
AUTHORS ' CONCLUSIONS Feeding with a soy formula can not be recommended for prevention of allergy or food intolerance in infants at high risk of allergy or food intolerance .
BACKGROUND Allergies and food reactions in infants and children are common and may be associated with a variety of foods including adapted cow 's milk formula .
Soy based formulas have been used to treat infants with allergy or food intolerance .
However , it is unclear whether they can help prevent allergy and food intolerance in infants without clinical evidence of allergy or food intolerance .
OBJECTIVES To determine the effect of feeding adapted soy formula compared to human milk , cow 's milk formula or a hydrolysed protein formula on preventing allergy or food intolerance in infants without clinical evidence of allergy or food intolerance .