There were no significant effects of organisational  interventions on lipid profile , HbA1c , medication adherence or recurrent cardiovascular events .
Pooled results indicated that educational interventions were not associated with clear differences in any of the review outcomes .
The estimated effects of organisational interventions were compatible with improvements and no differences in several modifiable risk factors .
BACKGROUND People with stroke or transient ischaemic attack ( TIA ) are at increased risk of future stroke and other cardiovascular events .
Evidence -based strategies for secondary stroke prevention have been established .
However , the implementation of prevention strategies could be improved .
OBJECTIVES To assess the effects of stroke service interventions for implementing secondary stroke prevention strategies on modifiable risk factor control , including patient adherence to prescribed medications , and the occurrence of secondary cardiovascular events .
A cluster randomised controlled trial of pharmacist led statin outreach support (SOS) in primary care: design and baseline characteristics.
BACKGROUND Statins reduce the risk of vascular events , however statin prescribing is often sub optimal and better evidence is needed to inform quality improvements . The Statin Outreach Support ( SOS ) trial was design ed to test the efficacy of pharmacist led educational outreach directed at General Practice s , aim ing to improve statin prescribing for community dwelling patients with vascular disease . This paper describes the study rationale , design , methods and baseline characteristics of participants . DESIGN The SOS trial was design ed to investigate whether practice s receiving SOS improve their statin prescribing and patients achieve reduced cholesterol levels . It was a prospect i ve , single blind , cluster r and omised controlled trial with a follow-up period of 5months minimum post SOS intervention delivery . RESULTS Thirty one practice s were recruited from the UK 's largest Health Board area . At r and omisation , 16 practice s were allocated to SOS and 15 to usual care with 4040 patients included at baseline . Participating practice s showed few differences compared with non-participating practice s ; practice s and patients r and omised to each arm of the study had similar distributions with respect to age , complications , cholesterol levels and statin prescribing . Baseline data compared favourably with l and mark , placebo-controlled statin trials . CONCLUSIONS Compared with existing implementation research , SOS trial has more participants , a detailed description of baseline characteristics and over 90 % power ( at 5 % significance ) to detect a difference of 12 % in the proportion of patients with controlled cholesterol after SOS
There were no significant effects of organisational  interventions on lipid profile , HbA1c , medication adherence or recurrent cardiovascular events .
Pooled results indicated that educational interventions were not associated with clear differences in any of the review outcomes .
The estimated effects of organisational interventions were compatible with improvements and no differences in several modifiable risk factors .
BACKGROUND People with stroke or transient ischaemic attack ( TIA ) are at increased risk of future stroke and other cardiovascular events .
Evidence -based strategies for secondary stroke prevention have been established .
However , the implementation of prevention strategies could be improved .
OBJECTIVES To assess the effects of stroke service interventions for implementing secondary stroke prevention strategies on modifiable risk factor control , including patient adherence to prescribed medications , and the occurrence of secondary cardiovascular events .