The majority of adverse events associated with CNTKA were minor and comparable with those seen with conventional TKA .
Clinical outcomes were comparable between the two techniques , with longer-term follow-up suggesting that CNTKA provided no benefit over conventional TKA in terms of sustained functional improvements .
At present , it is unclear whether the significant improvements shown in radiological outcomes after CNTKA translate to measurable clinical benefits .
BACKGROUND Conventional total knee arthroplasty ( TKA ) and the more recently available computer-navigated total knee arthroplasty ( CNTKA ) use alternative methods to achieve correct limb alignment .
This systematic review was undertaken to assess the safety and effectiveness of CNTKA compared with conventional TKA .
Coronal alignment correlates with outcome after total knee arthroplasty: five-year follow-up of a randomized controlled trial.
In a prospect i ve r and omized control trial comparing computer-assisted vs conventional total knee arthroplasty  , we previously reported that patients with coronal alignment within 3 ° of neutral had superior international knee society and Short-Form 12 ( SF-12 ) physical scores at 6 weeks , 3 months , 6 months , and 12 months after surgery . Computer-assisted total knee arthroplasty achieved greater accuracy in implant alignment , and this correlated with better knee function and quality of life . At 5 years , 90 of 111 patients assessed in our original study were review ed . Coronal alignment within 3 ° of neutral continued to be correlated with superior International Knee Society and SF-12 scores . Coronal alignment greater than 3 ° was associated with a significant decline in SF-12 mental health scores
The majority of adverse events associated with CNTKA were minor and comparable with those seen with conventional TKA .
Clinical outcomes were comparable between the two techniques , with longer-term follow-up suggesting that CNTKA provided no benefit over conventional TKA in terms of sustained functional improvements .
At present , it is unclear whether the significant improvements shown in radiological outcomes after CNTKA translate to measurable clinical benefits .
BACKGROUND Conventional total knee arthroplasty ( TKA ) and the more recently available computer-navigated total knee arthroplasty ( CNTKA ) use alternative methods to achieve correct limb alignment .
This systematic review was undertaken to assess the safety and effectiveness of CNTKA compared with conventional TKA .