This meta- analysis demonstrated that resveratrol supplementation among patients with MetS and related disorders  significantly reduced total cholesterol and increased GGT concentrations , but did not affect triglycerides , LDL- , HDL-cholesterol , ALT , and AST concentrations .
This data suggests that resveratrol may have a potential cardio-protective effect in patients with MetS and related disorders
There are current trials investigating the effect of resveratrol supplementation on lipid profiles and liver enzymes among patients with metabolic syndrome ( MetS ) and related disorders ; however , their findings are controversial .
This systematic review and meta- analysis were aim ed to determine the effects of resveratrol supplementation on lipid profiles and liver enzymes among patients with MetS and related disorders .
The effects of polyphenol supplementation on adipose tissue morphology and gene expression in overweight and obese humans
ABSTRACT Dietary polyphenols have beneficial effects on adipose tissue mass and function in rodents , but human studies are scarce . In a r and omized , placebo-controlled study , 25 ( 10 women ) overweight and obese humans received a combination of the polyphenols epigallocatechin-gallate and resveratrol ( 282 mg/d , 80 mg/d , respectively , EGCG+RES , n = 11 ) or placebo ( PLA , n = 14 ) supplementation for 12 weeks . Abdominal subcutaneous adipose tissue ( SAT ) biopsies were collected for assessment of adipocyte morphology and micro-array analysis . EGCG+RES had no effects on adipocyte size and distribution compared with PLA . However , we identified pathways contributing to adipogenesis , cell cycle and apoptosis were significantly downregulated by EGCG+RES versus PLA . Furthermore , EGCG+RES significantly decreased expression of pathways related to energy metabolism , oxidative stress , inflammation , and immune defense as compared with PLA . In conclusion , the SAT gene expression profile indicates a reduced cell turnover after 12-week EGCG+RES in overweight-obese subjects . It remains to be eluci date d whether these alterations translate into long-term metabolic effects
This meta- analysis demonstrated that resveratrol supplementation among patients with MetS and related disorders  significantly reduced total cholesterol and increased GGT concentrations , but did not affect triglycerides , LDL- , HDL-cholesterol , ALT , and AST concentrations .
This data suggests that resveratrol may have a potential cardio-protective effect in patients with MetS and related disorders
There are current trials investigating the effect of resveratrol supplementation on lipid profiles and liver enzymes among patients with metabolic syndrome ( MetS ) and related disorders ; however , their findings are controversial .
This systematic review and meta- analysis were aim ed to determine the effects of resveratrol supplementation on lipid profiles and liver enzymes among patients with MetS and related disorders .