There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Dietary Long-Chain Polyunsaturated Fatty Acids Do Not Influence Growth of Term Infants: A Randomized Clinical Trial
Objective . To determine if dietary long-chain polyunsaturated fatty acids ( LCPUFA ) affect the growth of formula-fed infants relative to breastfed infants . Methods . A r and omized , double-blind trial of three formula-fed groups and a parallel reference group of breastfed infants was conducted . The three treatments were a placebo ( no LCPUFA ) , docosahexaenoic acid ( DHA ) supplemented , and DHA plus arachidonic acid supplemented formulas fed for 12 months . Infant weight , length , head circumference , and fatty acid status were assessed at 6 , 16 , 34 weeks , and 1 year of age . Anthropometrics were repeated at 2 years of age . Results . There were no differences between the r and omized formula groups for weight , length , or head circumference even after adjustment for gender , gestational age , and the actual age at assessment . Post hoc regressions demonstrated a small negative association between DHA status at 16 weeks of age and weight at 1 and 2 years . Conclusions . Dietary LCPUFA do not influence growth of healthy term infants to a clinical ly significant degree
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .