The results of this systematic review indicate that the dietary supplementation with red yeast rice , bergamot , artichoke , and virgin olive oil has promising effects on the increase of HDL-C serum levels .
The artichoke leaf extract and virgin olive oil appear to be particularly interesting , while bergamot extract needs further research and the effect of red yeast rice seems to be limited to patients with previous myocardial infa rct ion .
Various MediterrAsian diet products or natural extracts may represent a potential intervention treatment to raise HDL-C in dyslipidemic subjects
Background .
High HDL-cholesterol ( HDL-C ) values are negatively correlated with cardiovascular diseases .
This review analyses the effect of the supplementation with various Mediterranean diet products ( artichoke , bergamot , and olive oil ) and Asian diet products ( red yeast rice ) on the  HDL-C value in dyslipidemic subjects .
Effects of differing phenolic content in dietary olive oils on lipids and LDL oxidation
Summary . Background : Evidence from in vitro studies suggests that antioxidant olive oil phenolic compounds can prevent LDL oxidation . However , in vivo evidence in support of this hypothesis is sparse . Aim of the study : to establish the antioxidant effect of olive oils with differences in their phenolic compounds content in humans Methods : A controlled , double blind , cross-over , r and omized , clinical trial using three similar olive oils with increasing phenolic concentration ( from 0 to 150 mg/Kg ) was conducted in 30 healthy volunteers .  Olive oils were administered over three periods of 3 weeks preceded by two-week washout periods . Results : Urinary tyrosol and hydroxytyrosol increased ( p < 0.020 ) , in vivo plasma oxidized LDL decreased ( p = 0.006 ) , and ex vivo resistance of LDL to oxidation increased ( p = 0.012 ) with the phenolic content of the olive oil administered . After virgin olive oil administration , an increase ( p = 0.029 ) was observed in HDL cholesterol levels . Conclusions : Sustained consumption of virgin olive oil with the high phenolic content was more effective in protecting LDL from oxidation and in rising HDL cholesterol levels than that of other type of olive oils . Dose-dependent changes in oxidative stress markers , and phenolic compounds in urine , were observed with the phenolic content of the olive oil administered . Our results support the hypothesis that virgin olive oil consumption could provide benefits in the prevention of oxidative processes
The results of this systematic review indicate that the dietary supplementation with red yeast rice , bergamot , artichoke , and virgin olive oil has promising effects on the increase of HDL-C serum levels .
The artichoke leaf extract and virgin olive oil appear to be particularly interesting , while bergamot extract needs further research and the effect of red yeast rice seems to be limited to patients with previous myocardial infa rct ion .
Various MediterrAsian diet products or natural extracts may represent a potential intervention treatment to raise HDL-C in dyslipidemic subjects
Background .
High HDL-cholesterol ( HDL-C ) values are negatively correlated with cardiovascular diseases .
This review analyses the effect of the supplementation with various Mediterranean diet products ( artichoke , bergamot , and olive oil ) and Asian diet products ( red yeast rice ) on the  HDL-C value in dyslipidemic subjects .