The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .
Randomized Evaluation of the Effects of Anacetrapib through Lipid-modification (REVEAL)—A large-scale, randomized, placebo-controlled trial of the clinical effects of anacetrapib among people with established vascular disease: Trial design, recruitment, and baseline characteristics
Background Patients with prior vascular disease remain at high risk for cardiovascular events despite intensive statin – based treatment . Inhibition of cholesteryl ester transfer protein by anacetrapib reduces low‐density lipoprotein ( LDL ) cholesterol by around 25 % to 40 % and more than doubles high‐density lipoprotein ( HDL ) cholesterol . However , it is not known if these apparently favorable lipid changes translate into reductions in cardiovascular events . Methods The REVEAL study is a r and omized , double‐blind , placebo‐controlled clinical trial that is assessing the efficacy and safety of adding anacetrapib to effective LDL‐lowering treatment with atorvastatin for an average of at least 4 years among patients with preexisting atherosclerotic vascular disease . The primary assessment is an intention‐to‐treat comparison among all r and omized participants of the effects of allocation to anacetrapib on major coronary events ( defined as the occurrence of coronary death , myocardial infa rct ion , or coronary revascularization ) . Results Between August 2011 and October 2013 , 30,449 individuals in Europe , North America , and China were r and omized to receive anacetrapib 100 mg daily or matching placebo .  Mean ( SD ) age was 67 ( 8) years , 84 % were male , 88 % had a history of coronary heart disease , 22 % had cerebrovascular disease , and 37 % had diabetes mellitus . At the r and omization visit ( after at least 8 weeks on a protocol ‐defined atorvastatin regimen ) , mean plasma LDL cholesterol was 61 ( 15 ) mg/dL and HDL cholesterol was 40 ( 10 ) mg/dL. Interpretation The REVEAL trial will provide a robust evaluation of the clinical efficacy and safety of adding anacetrapib to an effective statin regimen . Results are anticipated in 2017
The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .