RESULTS Increased TFA intake did not result in significant changes in glucose or insulin concentrations .
Our analysis also showed the absence of publication bias and any dose-response relations between the ES and TFA intake .
Increased TFA intake does not result in changes in glucose , insulin , or triglyceride concentrations but leads to an increase in total and LDL-cholesterol and a decrease in HDL-cholesterol concentrations .
There is no evidence to support a potential benefit of the reduction of dietary TFA intake on glucose homeostasis
BACKGROUND Although evidence from cohort studies has suggested that trans fatty acid ( TFA ) consumption may be associated with insulin resistance and diabetes , r and omized placebo-controlled trials ( RCTs ) have yielded conflicting results .
OBJECTIVE In a meta- analysis , we combined all available RCTs that examined the role of  TFA intake  on  glucose homeostasis .
Dietary fat and incidence of type 2 diabetes in older Iowa women.
OBJECTIVE To examine the associations between reported intakes of dietary fat and incident type 2 diabetes .  RESEARCH DESIGN AND METHODS We studied the relation between dietary fatty acids and diabetes in a prospect i ve cohort study of 35,988 older women who initially did not have diabetes .  Diet was assessed with a  food frequency question  naire at baseline , and 1,890 incident cases of diabetes occurred during 11 years of follow-up . RESULTS After adjusting for age , smoking , alcohol consumption , BMI , waist-to-hip ratio , physical activity , demographic factors , and dietary magnesium and cereal fiber , diabetes incidence was negatively associated with dietary polyunsaturated fatty acids , vegetable fat , and trans fatty acids and positively associated with omega-3 fatty acids , cholesterol , and the Keys score . After simultaneous adjustment for other dietary fat , only vegetable fat remained clearly related to diabetes risk . Relative risks across quintiles of vegetable fat intake were 1.00 , 0.90 , 0.87 , 0.84 , and 0.82 ( P = 0.02 ) . Diabetes risk was also inversely related to substituting polyunsaturated fatty acids for saturated fatty acids and positively correlated to the Keys dietary score . CONCLUSIONS These data support an inverse relation between incident type 2 diabetes and vegetable fat and substituting polyunsaturated fatty acids for saturated fatty acids and cholesterol
RESULTS Increased TFA intake did not result in significant changes in glucose or insulin concentrations .
Our analysis also showed the absence of publication bias and any dose-response relations between the ES and TFA intake .
Increased TFA intake does not result in changes in glucose , insulin , or triglyceride concentrations but leads to an increase in total and LDL-cholesterol and a decrease in HDL-cholesterol concentrations .
There is no evidence to support a potential benefit of the reduction of dietary TFA intake on glucose homeostasis
BACKGROUND Although evidence from cohort studies has suggested that trans fatty acid ( TFA ) consumption may be associated with insulin resistance and diabetes , r and omized placebo-controlled trials ( RCTs ) have yielded conflicting results .
OBJECTIVE In a meta- analysis , we combined all available RCTs that examined the role of  TFA intake  on  glucose homeostasis .