Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .
Garlic supplementation and lipoprotein oxidation susceptibility
Interventions which make serum lipoproteins less susceptible to oxidation may be antiatherogenic . The antioxidant properties of garlic which have been demonstratedin vitro led us to investigate the effects of garlic supplements on lipoprotein oxidation susceptibility in humans . Ten healthy volunteers were given 600 mg/d of garlic powder ( 6 tablets of Kwai ® ) for two weeks in a placebo-controlled , r and omized , double-blind crossover trial . We found that although serum lipid and lipoprotein levels were not lowered in this short time period , theex vivo susceptibility of apolipoprotein B-containing lipoproteins to oxidation was significantly decreased ( −34 % ) . Because garlic has been reported to beneficially affect serum lipid levels , platelet function , fibrinolysis and blood pressure , this additional effect of retarding lipoprotein oxidation may contribute to the potential antiatherosclerotic effect of garlic
Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .