For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?
Accuracy of Digital Breast Tomosynthesis for Depicting Breast Cancer Subgroups in a UK Retrospective Reading Study (TOMMY Trial).
PURPOSE To compare the diagnostic performance of two-dimensional ( 2D ) mammography , 2D mammography plus digital breast tomo synthesis ( DBT ) , and synthetic 2D mammography plus DBT in depicting malignant radiographic features . MATERIAL S AND METHODS In this multicenter , multireader , retrospective reading study ( the TOMMY trial ) , after written informed consent was obtained , 8869 women ( age range , 29 - 85 years ; mean , 56 years ) were recruited from July 2011 to March 2013 in an ethically approved study . From these women , a reading data set of 7060 cases was r and omly allocated for independent blinded review of ( a ) 2D mammography images , ( b ) 2D mammography plus DBT images , and ( c ) synthetic 2D mammography plus DBT images . Review ers had no access to results of previous examinations . Overall sensitivities and specificities were calculated for younger women and those with dense breasts . RESULTS Overall sensitivity was 87 % for 2D mammography , 89 % for 2D mammography plus DBT , and 88 % for synthetic 2D mammography plus DBT . The addition of DBT was associated with a 34 % increase in the odds of depicting cancer ( odds ratio [ OR ] = 1.34 , P = .06 ) ; however , this level did not achieve significance . For patients aged 50 - 59 years old , sensitivity was significantly higher ( P = .01 ) for 2D mammography plus DBT than it was for 2D mammography . For those with breast density of 50 % or more , sensitivity was 86 % for 2D mammography compared with 93 % for 2D mammography plus DBT ( P = .03 ) . Specificity was 57 % for 2D mammography , 70 % for 2D mammography plus DBT , and 72 % for synthetic 2D mammography plusmDBT . Specificity was significantly higher than 2D mammography ( P < .001 in both cases ) and was observed for all subgroups ( P < .001 for all cases ) . CONCLUSION The addition of DBT increased the sensitivity of 2D mammography in patients with dense breasts and the specificity of 2D mammography for all subgroups . The use of synthetic 2D DBT demonstrated performance similar to that of st and ard 2D mammography with DBT . DBT is of potential benefit to screening programs , particularly in younger women with dense breasts . ( © ) RSNA , 2015
For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?