Criterion validity for three of these measures was established in NSCLC but not the reliability or responsiveness .
Background The measurement properties of instruments used to assess functional capacity , physical activity and muscle strength in participants with non-small cell lung cancer ( NSCLC ) have not been systematic ally review ed .
Method Objectives : To identify outcome measures used to assess these outcomes in participants with NSCLC ; and to evaluate , synthesis e and compare the measurement properties of the outcome measures identified .
Peak Oxygen Consumption Measured during the Stair-Climbing Test in Lung Resection Candidates
Background : The stair-climbing test is commonly used in the preoperative evaluation of lung resection c and i date s , but it is difficult to st and ardize and provides little physiologic information on the performance . Objective : To verify the association between the altitude and the VO2peak measured during the stair-climbing test . Methods : 109 consecutive c and i date s for lung resection performed a  symptom-limited stair-climbing test with direct breath-by-breath measurement of VO2peak by a portable gas analyzer . Stepwise logistic regression and bootstrap analyses were used to verify the association of several perioperative variables with a VO2peak < 15 ml/kg/min . Subsequently , multiple regression analysis was also performed to develop an equation to estimate VO2peak from stair-climbing parameters and other patient-related variables . Results : 56 % of patients climbing < 14 m had a VO2peak < 15 ml/kg/min , whereas 98 % of those climbing > 22 m had a VO2peak > 15 ml/kg/min . The altitude reached at stair-climbing test result ed in the only significant predictor of a VO2peak < 15 ml/kg/min after logistic regression analysis . Multiple regression analysis yielded an equation to estimate VO2peak factoring altitude ( p < 0.0001 ) , speed of ascent ( p = 0.005 ) and body mass index ( p = 0.0008 ) . Conclusions : There was an association between altitude and VO2peak measured during the stair-climbing test . Most of the patients climbing more than 22 m are able to generate high values of VO2peak and can proceed to surgery without any additional tests . All others need to be referred for a formal cardiopulmonary exercise test . In addition , we were able to generate an equation to estimate VO2peak , which could assist in streamlining the preoperative workup and could be used across different setting s to st and ardize this test
Criterion validity for three of these measures was established in NSCLC but not the reliability or responsiveness .
Background The measurement properties of instruments used to assess functional capacity , physical activity and muscle strength in participants with non-small cell lung cancer ( NSCLC ) have not been systematic ally review ed .
Method Objectives : To identify outcome measures used to assess these outcomes in participants with NSCLC ; and to evaluate , synthesis e and compare the measurement properties of the outcome measures identified .