The present review demonstrates that vitamin D supplementation result ed in small but nonsignificant improvements in muscle strength compared to control in postmenopausal women .
No significant effect was observed in mobility after vitamin D administration
BACKGROUND The results obtained from previous trials regarding the effects of vitamin D supplementation on muscle strength and mobility  in postmenopausal women have been inconsistent .
This systematic review and meta- analysis of r and omised controlled trials ( RCTs ) aim ed to investigate the effect of vitamin D supplementation on muscle strength and mobility in postmenopausal women .
Effect of vitamin D supplementation alone on muscle function in postmenopausal women: a randomized, double-blind, placebo-controlled clinical trial
Summary The present study investigates the effects of vitamin D on muscle function in postmenopausal women . It has been shown that vitamin D supplementation in postmenopausal women with hypovitaminosis D provides significant protective factor against sarcopenia , with significant increases in muscle strength and control of progressive loss of lean mass . Introduction We aim ed to evaluate the effect of supplementation of vitamin D ( VITD ) alone on muscle function in younger postmenopausal women . Methods In this double-blind , placebo-controlled clinical trial , 160 Brazilian postmenopausal women were r and omized into two groups : VITD group consisting of patients receiving vitamin D3 1000 IU/day orally ( n = 80 ) or placebo group ( n = 80 ) . Women with amenorrhea for more than 12 months and age 50–65 years , with a history of falls ( previous 12 months ) , were included . The intervention time was 9 months , with assessment s at two points , start and end . Lean mass was estimated by total-body dual-energy X-ray absorptiometry ( DXA ) and muscle strength by h and grip strength and chair rising test . The plasma concentrations of 25-hydroxyvitamin D [ 25(OH)D ] were measured by high-performance liquid chromatography ( HPLC ) . Statistical analysis was by intention to treat ( ITT ) , using ANOVA , Student ’s t test , and Tukey ’s test . Results After 9 months , average values of 25(OH)D increased from 15.0 ± 7.5 to 27.5 ± 10.4 ng/ml ( + 45.4 % ) in the VITD group and decreased from 16.9 ± 6.7 to 13.8 ± 6.0 ng/ml ( −18.5 % ) in the placebo group ( p < 0.001 ) . In the VITD group , there was significant increase in muscle strength ( + 25.3 % ) of the lower limbs by chair rising test ( p = 0.036 ) . In women in the placebo group , there was considerable loss ( −6.8 % ) in the lean mass ( p = 0.030 ) . Conclusion The supplementation of vitamin D alone in postmenopausal women provided significant protective factor against the occurrence of sarcopenia , with significant increases in muscle strength and control of progressive loss of lean mass
The present review demonstrates that vitamin D supplementation result ed in small but nonsignificant improvements in muscle strength compared to control in postmenopausal women .
No significant effect was observed in mobility after vitamin D administration
BACKGROUND The results obtained from previous trials regarding the effects of vitamin D supplementation on muscle strength and mobility  in postmenopausal women have been inconsistent .
This systematic review and meta- analysis of r and omised controlled trials ( RCTs ) aim ed to investigate the effect of vitamin D supplementation on muscle strength and mobility in postmenopausal women .