In contrast , fasting plasma glucose , fasting plasma insulin as well as the homeostasis model assessment of insulin resistance were not affected by the amounts of MUFA in the dietary protocol s. Conclusions : In summary , this systematic review found that high MUFA diets appear to be effective in reducing HbA1c , and therefore , should be recommended in the dietary regimes of T2D
Background / Aims : In 2008 , the American Diabetes Association recommended low-carbohydrate or low-fat diets for weight management in patients with established type 2 diabetes ( T2D ) , while the amount of monounsaturated fatty acids ( MUFA ) was not specified .
This systematic review focused on the effects of diets high in MUFA versus diets low in MUFA on important risk factors of T2D ( i.e. plasma glucose , insulin , homeostasis model assessment of insulin resistance and glycosylated haemoglobin , HbA1c ) .
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study
BACKGROUND Intensive lifestyle interventions can reduce the incidence of  type 2 diabetes in people with impaired glucose tolerance , but how long these benefits extend beyond the period of active intervention , and whether such interventions reduce the risk of cardiovascular disease ( CVD ) and mortality , is unclear . We aim ed to assess whether intensive lifestyle interventions have a long-term effect on the risk of diabetes , diabetes-related macrovascular and microvascular complications , and mortality . METHODS In 1986 , 577 adults with impaired glucose tolerance from 33 clinics in China were r and omly assigned to either the  control group or to one of three lifestyle intervention groups ( diet , exercise , or diet plus exercise ) . Active intervention took place over 6 years until 1992 . In 2006 , study participants were followed-up to assess the long-term effect of the interventions . The primary outcomes were diabetes incidence , CVD incidence and mortality , and all-cause mortality . FINDINGS Compared with control participants , those in the combined lifestyle intervention groups had a 51 % lower incidence of diabetes ( hazard rate ratio [ HRR ] 0.49 ; 95 % CI 0.33 - 0.73 ) during the active intervention period and a 43 % lower incidence ( 0.57 ; 0.41 - 0.81 ) over the 20 year period , controlled for age and clustering by clinic . The average annual incidence of diabetes was 7 % for intervention participants versus 11 % in control participants , with 20-year cumulative incidence of 80 % in the intervention groups and 93 % in the control group . Participants in the intervention group spent an average of 3.6 fewer years with diabetes than those in the control group . There was no significant difference between the intervention and control groups in the rate of first CVD events ( HRR 0.98 ; 95 % CI 0.71 - 1.37 ) , CVD mortality ( 0.83 ; 0.48 - 1.40 ) , and all-cause mortality ( 0.96 ; 0.65 - 1.41 ) , but our study had limited statistical power to detect differences for these outcomes . INTERPRETATION Group-based lifestyle interventions over 6 years can prevent or delay diabetes for up to 14 years after the active intervention . However , whether lifestyle intervention also leads to reduced CVD and mortality remains unclear
In contrast , fasting plasma glucose , fasting plasma insulin as well as the homeostasis model assessment of insulin resistance were not affected by the amounts of MUFA in the dietary protocol s. Conclusions : In summary , this systematic review found that high MUFA diets appear to be effective in reducing HbA1c , and therefore , should be recommended in the dietary regimes of T2D
Background / Aims : In 2008 , the American Diabetes Association recommended low-carbohydrate or low-fat diets for weight management in patients with established type 2 diabetes ( T2D ) , while the amount of monounsaturated fatty acids ( MUFA ) was not specified .
This systematic review focused on the effects of diets high in MUFA versus diets low in MUFA on important risk factors of T2D ( i.e. plasma glucose , insulin , homeostasis model assessment of insulin resistance and glycosylated haemoglobin , HbA1c ) .