Similar effects also appeared in SBP and DBP categories regardless of follow-up duration .
PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions .
In adults without IGT or diabetes , lifestyle interventions result ed in significant improvements in SBP , DBP , TC , LDL-C , HDL-C , and TG , and might further reduce CVD risk
Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease ( CVD ) risk among persons with impaired glucose tolerance ( IGT ) , but it is unclear whether they should be implemented among persons without IGT .
We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes .
Community Trial of a Faith-Based Lifestyle Intervention to Prevent Diabetes Among African-Americans
Abstract About 75 % of African-Americans ( AAs ) ages 20 or older are overweight and nearly 50 % are obese , but community-based programs to reduce diabetes risk in AAs are rare . Our objective was to reduce weight and fasting plasma glucose ( FPG ) and increase physical activity ( PA ) from baseline to week-12 and to month-12 among overweight AA parishioners through a faith-based adaptation of the Diabetes Prevention Program called Fit Body and Soul ( FBAS ) . We conducted a single-blinded , cluster r and omized , community trial in 20 AA churches enrolling 604 AAs , aged 20–64 years with BMI ≥ 25 kg/m2 and without diabetes . The church ( and their parishioners ) was r and omized to FBAS or health education ( HE ) . FBAS participants had a significant difference in adjusted weight loss compared with those in HE ( 2.62 vs. 0.50 kg , p = 0.001 ) at 12-weeks and ( 2.39 vs. −0.465 kg , p = 0.005 ) at 12-months and were more likely ( 13 % ) than HE participants ( 3 % ) to achieve a 7 % weight loss ( p < 0.001 ) at 12-weeks and a 7 % weight loss ( 19 vs. 8 % , p < 0.001 ) at 12-months . There were no significant differences in FPG and PA between arms . Of the 15.2 % of participants with baseline pre-diabetes , those in FBAS had , however , a significant decline in FPG ( 10.93 mg/dl ) at 12-weeks compared with the 4.22 mg/dl increase in HE ( p = 0.017 ) , and these differences became larger at 12-months ( FBAS , 12.38 mg/dl decrease ; HE , 4.44 mg/dl increase ) ( p = 0.021 ) . Our faith-based adaptation of the DPP led to a significant reduction in weight overall and in FPG among pre-diabetes participants . Clinical Trials.gov Identifier NCT01730196
Similar effects also appeared in SBP and DBP categories regardless of follow-up duration .
PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions .
In adults without IGT or diabetes , lifestyle interventions result ed in significant improvements in SBP , DBP , TC , LDL-C , HDL-C , and TG , and might further reduce CVD risk
Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease ( CVD ) risk among persons with impaired glucose tolerance ( IGT ) , but it is unclear whether they should be implemented among persons without IGT .
We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes .