In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .
Effect of zinc supplementation on in vitro copper-induced oxidation of low-density lipoproteins in healthy French subjects aged 55-70 years: the Zenith Study.
Zn has been shown to possess antioxidant properties in vitro and in vivo . As inadequate dietary Zn intake has been reported in these population s , Zn supplementation may protect against oxidative stress and thereby limit the progression of degenerative diseases in such population s. We conducted the present study to evaluate the long-term supplementation effects of two moderate doses of Zn on in vitro Cu-induced LDL oxidation in French men and women . Three groups of sixteen healthy subjects aged 55 - 70 years from each sex participated in this r and omized double-blind , placebo-controlled study . Each group received for six months either 0 , 15 or 30 mg supplemental Zn per d. At the beginning and at the end of the supplementation periods , dietary intakes of Zn , Cu , Fe and vitamin E were estimated using 4 d food-intake records ( including the weekend ) and the GENI program . Zn , Cu , Fe and vitamin E status were also determined . In vitro LDL oxidizability ( basal conjugated diene level , maximal conjugated diene formation and lag time ) and lipid parameters were also determined . Dietary intakes of Zn , Cu , Fe and vitamin E were adequate in this population . Zn supplementation significantly increased serum Zn levels but did not significantly modify Cu , Fe or vitamin E status . However , Zn supplementation had no effect on in vitro LDL oxidation parameters , nor were there any sex-related differences in in vitro LDL oxidizability . The present study showed that long-term Zn supplementation of healthy subjects aged 55 - 70 years had no effect on in vitro Cu-induced LDL oxidation under the study conditions
In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .