No quantitative synthesis was attempted for either mebiomian plugging or meibomian secretion scores and no significant changes were observed with any other outcome parameter .
Conclusion : Only the systemic antimicrobials were found to improve the clinical features of meibomian gl and dysfunction .
Varying effects of different therapeutic agents ( heat therapies , omega-3-fatty acids and castor oil ) were identified for MGD but the risk of bias pertaining to r and omization and allocation concealment was found to be associated with most of the current RCTs .
Introduction : Meibomian Gl and Dysfunction ( MGD ) is a common , often overlooked , chronic condition affecting eyes for which various therapies are being evaluated .
Considering the absence of a systematic review and meta- analysis , the present review was carried out .
Prevalence of dry eye among adult Chinese in the Beijing Eye Study
Purpose To study the prevalence and associations of dry eye symptoms in adult Chinese . Methods The Beijing Eye Study is a population -based study in northern China , which included 4439 of 5324 subjects invited to participate with an age of 40 + years ( response rate : 83.4 % ) . For the present study , a r and om sample was taken consisting of 1957(44.1 % ) subjects ( 1112 women ; 56.9 % ) .  Dry eye symptoms were evaluated with ( 1 ) an  interviewer-assisted question naire ; ( 2 )  measurement of the tear-film break-up time ; ( 3 ) assessment of the fluorescein staining of the cornea ; ( 4 ) slit-lamp-based examination of a meibomian gl and dysfunction ;  and ( 5 ) Schirmer 's test .  Results Symptoms of a dry eye felt ‘ often ’ or ‘ at all times ’ were present in 411 subjects ( 21.0 % ) . In a multivariate analysis , dry eye symptoms were significantly associated with age ( P<0.001 ) , female gender ( P<0.001 ; odds ratio ( OR ) : 1.56 ; 95 % confidence intervals ( CI ) : 1.23 , 1.98 ) , urban region ( P<0.001;OR : 1.89 ; 95 % CI : 1.46 , 2.48 ) , low degree of nuclear cataract ( P=0.02 ) , and undercorrection of refractive error ( P=0.005 ; OR : 1.42 ; 95 % CI : 1.11 , 1.82 ) . All tests for dry eye did not vary significantly between the dry eye group and the normal group . Conclusions The dry eye symptoms as evaluated subjectively in a question naire occurred in about 21 % of the adult population in China , with associations to age , female gender , urban region , and undercorrection of a refractive error . Measurement of the tear-film break-up time , assessment of the corneal fluorescein staining , slit-lamp-based examination of a meibomian gl and dysfunction , and Schirmer 's test were not significantly associated with dry eye symptoms
No quantitative synthesis was attempted for either mebiomian plugging or meibomian secretion scores and no significant changes were observed with any other outcome parameter .
Conclusion : Only the systemic antimicrobials were found to improve the clinical features of meibomian gl and dysfunction .
Varying effects of different therapeutic agents ( heat therapies , omega-3-fatty acids and castor oil ) were identified for MGD but the risk of bias pertaining to r and omization and allocation concealment was found to be associated with most of the current RCTs .
Introduction : Meibomian Gl and Dysfunction ( MGD ) is a common , often overlooked , chronic condition affecting eyes for which various therapies are being evaluated .
Considering the absence of a systematic review and meta- analysis , the present review was carried out .