Intensive glycaemic control does not seem to reduce all cause mortality in patients with type 2 diabetes .
OBJECTIVE To assess the effect of targeting intensive glycaemic control versus conventional glycaemic control on  all cause mortality and cardiovascular mortality , non-fatal myocardial infa rct ion , microvascular complications , and severe hypoglycaemia in patients with type 2 diabetes .
Effects of insulin treatment on cause-specific one-year mortality and morbidity in diabetic patients with acute myocardial infarction. DIGAMI Study Group. Diabetes Insulin-Glucose in Acute Myocardial Infarction.
Diabetic patients with acute myocardial infa rct ion have a poor prognosis , which has been attributed to a higher incidence of congestive heart failure and fatal reinfa rct ion . This study reports on the one-year morbidity and mortality in a r and omized study with the aim of testing whether insulin-glucose infusion initiated as soon as possible after onset of myocardial infa rct ion and followed by long-term subcutaneous insulin treatment may have a beneficial effect on outcome in diabetic patients . In all , 306 patients were recruited to the insulin-treated group , while 314 patients served as controls .  The overall mortality after one year was 19 % in the insulin group compared to 26 % among controls ( P < 0.05 ) . The treatment effect was most pronounced in patients without prior insulin medication and at low cardiovascular risk . In this stratum the in-hospital mortality was reduced by 58 % ( P < 0.05 ) and the one-year mortality by 52 % ( P < 0.02 ) . The most frequent cause of death in all patients was congestive heart failure ( 66 % ) , but cardiovascular mortality ( congestive heart failure , fatal reinfa rct ion , sudden death and stroke ) tended to be decreased in insulin-treated patients . However , this difference did not reach the level of statistical significance . The number of reinfa rct ions was 53 ( 28 % fatal ) in the insulin group compared to 55 ( 45 % fatal ) in the control group . The two groups did not differ as regards need for hospital care or coronary revascularization during the year of follow-up . In summary , left ventricular failure and fatal reinfa rct ions contribute to increased mortality in diabetic patients following acute myocardial infa rct ion . Intensive insulin treatment lowered this mortality during one year of follow-up
Intensive glycaemic control does not seem to reduce all cause mortality in patients with type 2 diabetes .
OBJECTIVE To assess the effect of targeting intensive glycaemic control versus conventional glycaemic control on  all cause mortality and cardiovascular mortality , non-fatal myocardial infa rct ion , microvascular complications , and severe hypoglycaemia in patients with type 2 diabetes .