Whether or not outcomes such as osteoporosis ( or low bone mass ) and specific types of cancer may be prevented by ' generous ' vitamin D supplementation is unclear and mostly based on indirect epidemiologic data not clearly substantiated by r and omized controlled trials SUMMARY The dose of daily vitamin D supplements needed to prevent rickets is probably much lower than that recommended by most expert committees .
PURPOSE OF REVIEW To underst and the basis for current recommendations for  vitamin D supplementation in childhood and the differences between the recommendations published by major expert committees , using the Medline engine of the US National Library of Medicine and the National Institutes of Health .
Most trials have examined the question of whether a specific daily vitamin D dose is capable or not to prevent rickets ( by study ing surrogate markers of rickets ) .
Bone mineral content and serum 25-hydroxyvitamin D concentrations in breast-fed infants with and without supplemental vitamin D: one-year follow-up.
in association with hypothyroidism . We did not obtain parietal cell or intrinsic factor antibodies . There was no evidence of other au to immune diseases or deficiencies in the mother ( or int2ant ) on the basis of routine clinical and laboratory tests . Breast-fed infants are at risk for nutr i t ional deficiencies if the mother is malnourished , a vegan , or if she has an abnormali ty in nut r ien t metabolism . Physicians should be aware tha t even with a well-balanced mate rna l diet , an occasional breast-fed infant can develop a serious nutritional deficiency
Whether or not outcomes such as osteoporosis ( or low bone mass ) and specific types of cancer may be prevented by ' generous ' vitamin D supplementation is unclear and mostly based on indirect epidemiologic data not clearly substantiated by r and omized controlled trials SUMMARY The dose of daily vitamin D supplements needed to prevent rickets is probably much lower than that recommended by most expert committees .
PURPOSE OF REVIEW To underst and the basis for current recommendations for  vitamin D supplementation in childhood and the differences between the recommendations published by major expert committees , using the Medline engine of the US National Library of Medicine and the National Institutes of Health .
Most trials have examined the question of whether a specific daily vitamin D dose is capable or not to prevent rickets ( by study ing surrogate markers of rickets ) .