Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .
Percutaneous tibial nerve stimulation effects on detrusor overactivity incontinence are not due to a placebo effect: a randomized, double-blind, placebo controlled trial.
PURPOSE This is a prospect i ve , double-blind , placebo controlled study , based on an original placebo technique , performed to evaluate the efficacy of percutaneous tibial nerve stimulation in female patients with detrusor overactivity incontinence . MATERIAL S AND METHODS A total of 35 female patients presenting with detrusor overactivity incontinence that did not respond to antimuscarinic therapy were r and omly assigned to percutaneous tibial nerve stimulation or to a control group . The  percutaneous tibial nerve stimulation group ( 18 patients ) was treated with 12 percutaneous tibial nerve stimulation sessions . The control group ( 17 patients ) received an original placebo treatment using a 34 gauge needle placed in the medial part of the gastrocnemius muscle . The sessions lasted for 30 minutes and were performed 3 times weekly as percutaneous tibial nerve stimulation sessions . All patients were evaluated with bladder diaries as well as quality of life scores before and after treatment . Patients showing a reduction in urge incontinence episodes greater than 50 % were considered responders . RESULTS Some patients ( 1 in the percutaneous tibial nerve stimulation group and 2 in the placebo group ) did not complete the study for reasons not related to the technique . Of 17 patients in the percutaneous tibial nerve stimulation group 12 ( 71 % ) and of 15 in placebo group 0 were considered responders according to the previously reported definition ( p < 0.001 ) . Improvement in the number of incontinence episodes , number of voids , voided volume and incontinence quality of life score were statistically significant in the percutaneous tibial nerve stimulation group but not in the placebo group . CONCLUSIONS Percutaneous tibial nerve stimulation can be considered an effective treatment for detrusor overactivity incontinence with 71 % of patients considered responders , while none of those treated with placebo was considered a responder . The relevance of a placebo effect seems to be negligible in this patient population
Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .