This meta- analysis concludes that hypovitaminosis D is associated with increased risk of hyperglycemia both in diabetic and non-diabetic subjects .
There is evidence that vitamin D status is associated with type 2 diabetes .
Many observational studies have been performed investigating the relationship of vitamin D status and circulating biomarkers of glycemic regulation .
To find out whether this association holds , we conducted a systematic review and meta- analysis of cross sectional and longitudinal studies .
Predicted 25-hydroxyvitamin D score and change in fasting plasma glucose in the Framingham offspring study
Data on the association between vitamin D status and actual change in glycemic measures are limited . We examined the prospect i ve association between a predicted 25-hydroxyvitamin D ( 25(OH)D ) score and change in fasting plasma glucose concentration over a mean follow-up of 7 years , in 2571 men and women ( mean age 54 years ) without diabetes in the Framingham Offspring Study cohort . After adjustment for age , sex , body mass index and fasting plasma glucose at baseline , higher predicted 25(OH)D score at baseline was associated with a smaller 7-year increase in fasting plasma glucose concentrations ( 0.23 mmol/l versus 0.35 mmol/l for highest versus lowest tertile of 25(OH)D score , respectively , P-trend=0.002 ) . Vitamin D status may be an important determinant for change in fasting plasma glucose concentration among middle-aged and older adults without diabetes
This meta- analysis concludes that hypovitaminosis D is associated with increased risk of hyperglycemia both in diabetic and non-diabetic subjects .
There is evidence that vitamin D status is associated with type 2 diabetes .
Many observational studies have been performed investigating the relationship of vitamin D status and circulating biomarkers of glycemic regulation .
To find out whether this association holds , we conducted a systematic review and meta- analysis of cross sectional and longitudinal studies .