Although most study - authors were positive , we could not draw firm conclusions about any of the pharmaceutical interventions .
Even patients that received placebo intervention showed improvement .
There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo .
Conclusions There is no evidence at all about the prevention of intertrigo and there is no firm evidence about its treatment .
Background Intertrigo in the large skin folds is a common problem .
There is a plethora of treatments , but a lack of evidence about their efficacy .
A nursing guideline on this matter had to be up date d and broadened in scope to other health care professionals .
Problems with clinical trials in general practice--a double-blind comparison of cream containing miconazole and hydrocortisone with hydrocortisone alone in the treatment of intertrigo.
A double-blind comparative study between 1 % hydrocortisone cream and a combination of 1 % hydrocortisone cream and 2 % miconazole cream has highlighted some of the problems with this type of research in general practice . The collection of adequate patient numbers within a predefined time scale proved a major problem . However , the study demonstrated the safety and efficacy of both these preparations in the treatment of intertrigo
Although most study - authors were positive , we could not draw firm conclusions about any of the pharmaceutical interventions .
Even patients that received placebo intervention showed improvement .
There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo .
Conclusions There is no evidence at all about the prevention of intertrigo and there is no firm evidence about its treatment .
Background Intertrigo in the large skin folds is a common problem .
There is a plethora of treatments , but a lack of evidence about their efficacy .
A nursing guideline on this matter had to be up date d and broadened in scope to other health care professionals .