According to the network meta- analysis the Mediterranean diet is the most effective and efficacious dietary approach to improve glycaemic control in type 2 diabetes patients
The aim of the present study is to assess the comparative efficacy of different dietary approaches on glycaemic control in patients with type 2 diabetes mellitus using a systematic review of the literature .
Placebo-controlled trial of the effects of guar gum and metformin on fasting blood glucose and serum lipids in obese, type 2 diabetic patients.
Nineteen obese patients with Type 2 diabetes mellitus were treated for periods of 3 months with placebo , guar gum ( 5 g three times daily ) and metformin ( 500 mg three times daily ) in a r and omized double-blind , double-placebo , cross-over study . Both active agents decreased fasting blood glucose from 11.4 + /- 3.7 mmol l-1 ( mean + /- SD ) to 8.6 + /- 2.8 mmol l-1 on metformin ( p less than 0.001 ) and to 9.5 + /- 3.9 mmol l-1 on guar gum ( p less than 0.01 ) . Metformin significantly reduced the very low density lipoprotein ( VLDL ) cholesterol concentration from 0.62 ( + 0.73 , -0.34 ) mmol l-1 ( geometric mean ( + SD , -SD ) ) to 0.43 ( + 0.58 , -0.25 ) mmol l-1 , ( p less than 0.02 ) , but unless hyperlipidaemia was present there were no changes in other serum lipid or lipoprotein levels . In patients with serum cholesterol greater than 6.5 mmol l-1 decreases in serum triglycerides from 3.29 ( + 3.27 , -1.64 ) to 2.46 ( + 2.55 , -1.25 ) mmol l-1 ( p less than 0.02 ) occurred with metformin . In these patients guar gum produced a reduction in serum cholesterol ( from 7.70 + /- 0.90 to 6.41 + /- 1.11 mmol l-1 , p less than 0.01 ) due to an effect on low density lipoproteins . These differential effects may be important in planning therapy when hyperlipidaemia accompanies Type 2 diabetes
According to the network meta- analysis the Mediterranean diet is the most effective and efficacious dietary approach to improve glycaemic control in type 2 diabetes patients
The aim of the present study is to assess the comparative efficacy of different dietary approaches on glycaemic control in patients with type 2 diabetes mellitus using a systematic review of the literature .