Discussion : Ablative lasers seem to achieve the highest degree of efficacy , albeit this is associated with significant pain and downtime , and the risk for long-term pigmentary changes .
Non-ablative fractional photothermolysis ( FP ) has a much safer profile but can not achieve as good cosmetic results .
The efficacies of fractional radiofrequency microneedling and radiofrequency are slightly inferior to that of FP but offer an even safer adverse profile .
Conclusion : Multiple devices have been used with varying levels of efficacy and very different safety profiles .
There is an overall lack of high- quality evidence about the effects of different interventions .
Introduction : Acne scarring is a very common problem , which can be extensive , and may lead to significant psychosocial morbidity .
Multiple types of treatments are used to ameliorate atrophic scars with varying degrees of success .
This paper provides an overview of the various energy-based modalities that are commonly employed against acne scarring .
Objectives and methods : A comprehensive literature search of papers published since 2008 was performed in order to determine the efficacy and adverse reactions of commonly used energy-based treatments against post-acne scarring .
Autologous Platelet Rich Plasma: Topical Versus Intradermal After Fractional Ablative Carbon Dioxide Laser Treatment of Atrophic Acne Scars
BACKGROUND A proposal has recently been made regarding the potential adjuvant use of platelet‐rich plasma ( PRP ) with fractional carbon dioxide laser ( FCL ) for the correction of acne scars . OBJECTIVE To compare the efficacy and safety of two administration modes of autologous PRP ( intradermal injection ( ID ) and topical application ) after FCL with that of FCL alone in the treatment of atrophic acne scars . PATIENTS AND METHODS Thirty patients were r and omly divided into two groups . Both underwent split‐face therapy . Group 1 was administered FCL followed by ID PRP on one side and FCL followed by ID saline on the other . In group 2 , one cheek was treated with FCL followed by ID PRP , and the other received FCL followed by topical PRP . Each patient received 3 monthly sessions . The final assessment took place at 6 months . RESULTS Combined PRP‐ and FCL‐treated areas had a significantly better response ( p = .03 ) , fewer side effects , and shorter downtime ( p = .02 ) than FCL‐treated areas , but there were no significant differences in ID‐ and topical PRP – treated areas in degree of response and downtime ( p = .10 ) ; topically treated areas had significantly lower pain scores . CONCLUSION The current study introduces the combination of topical PRP and FCL as an effective , safe modality in the treatment of atrophic acne scars with shorter downtime than FCL alone and better tolerability than FCL combined with ID PRP
Discussion : Ablative lasers seem to achieve the highest degree of efficacy , albeit this is associated with significant pain and downtime , and the risk for long-term pigmentary changes .
Non-ablative fractional photothermolysis ( FP ) has a much safer profile but can not achieve as good cosmetic results .
The efficacies of fractional radiofrequency microneedling and radiofrequency are slightly inferior to that of FP but offer an even safer adverse profile .
Conclusion : Multiple devices have been used with varying levels of efficacy and very different safety profiles .
There is an overall lack of high- quality evidence about the effects of different interventions .
Introduction : Acne scarring is a very common problem , which can be extensive , and may lead to significant psychosocial morbidity .
Multiple types of treatments are used to ameliorate atrophic scars with varying degrees of success .
This paper provides an overview of the various energy-based modalities that are commonly employed against acne scarring .
Objectives and methods : A comprehensive literature search of papers published since 2008 was performed in order to determine the efficacy and adverse reactions of commonly used energy-based treatments against post-acne scarring .