Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .
Carbonated beverages and urinary calcium excretion.
BACKGROUND Intake of carbonated beverages has been associated with increased fracture risk in observational studies . The usual explanation given is that one or more of the beverage constituents increase urinary calcium . OBJECTIVE We assessed the short-term effects on urinary calcium excretion of carbonated beverages of various compositions . DESIGN An incomplete r and om block design was used to study 20 - 40-y-old women who customarily consumed > or = 680 mL carbonated beverages daily . Four carbonated beverages were tested : 2 with caffeine and 2 without . Two contained phosphoric acid as the acidulant and 2 contained citric acid . The study included one neutral control ( water ) and one positive control ( skim or chocolate milk ) . Serving size was 567 mL for the carbonated beverages and water and 340 mL for the milks . Beverages were consumed with a light breakfast after an overnight fast ; no other foods were ingested until urine collection was complete . pH , titratable and total acidity , sodium , creatinine , and calcium were measured in 2-h ( morning ) fasting and 5-h postbeverage urine specimens . RESULTS Relative to water , urinary calcium rose significantly only with the milks and the 2 caffeine-containing beverages . The excess calciuria was approximately 0.25 mmol , about the same as previously reported for caffeine alone . Phosphoric acid without caffeine produced no excess calciuria ; nor did it augment the calciuria of caffeine . CONCLUSIONS The excess calciuria associated with consumption of carbonated beverages is confined to caffeinated beverages . Acidulant type has no acute effect . Because the caffeine effect is known to be compensated for by reduced calciuria later in the day , we conclude that the net effect of carbonated beverage constituents on calcium economy is negligible . The skeletal effects of carbonated beverage consumption are likely due primarily to milk displacement
Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .