The National Eye Institute Visual Function Question naire-25 , Impact of Vision Impairment and Treatment Satisfaction Survey-Intraocular Pressure had the highest number of positive ratings in the content validity assessment .
Conclusion This study provides a descriptive catalogue of vision-specific PRO instruments , to inform the choice of an appropriate measure of patient-reported outcomes in a glaucoma context
Purpose To identify  vision Patient-Reported Outcomes instruments relevant to glaucoma and assess their content validity .
Intraocular Pressure, Safety and Quality of Life in Glaucoma Patients Switching to Latanoprost from Adjunctive and Monotherapy Treatments
Purpose To evaluate efficacy , safety and quality of life in ocular hypertensive or open-angle glaucoma patients changed to latanoprost  from previous therapy . Methods A prospect i ve , multicenter , active-controlled design in which qualified patients had their previous therapy substituted for latanoprost  and were followed for at least thee months . Results In 1068 patients , latanoprost was continued 92 % throughout the 36-month observation period . Latanoprost treatment reduced the intraocular pressure (IOP)(p < 0.001 ) when compared to previous monotherapies including : beta-blockers ( -4.0 ± 3.7 mmHg , 42 % ) , alpha-antagonists ( -3.9 ± 3.0 mmHg , 14 % ) , miotics ( -3.8 ± 3.5 mmHg , 2 % ) , or carbonic anhydrase inhibitors ( CAI ) ( -3.8 ± 3.6 mmHg , n = 16 % ) , and adjunctive therapy including : beta-blocker and CAI ( -3.7 ± 3.1 mmHg , n = 12 % ) , alpha-agonist ( -3.7 ± 3.4 mmHg , n = 5 % ) , or pilocarpine ( -3.4 ± 3.7 mmHg , n = 6 % ) , or CAI and alpha-agonist ( -4.6 ± 6.4 mm Hg , n = 2%)(p < 0.0017 ) . The most common adverse event with latanoprost was ocular allergy ( 1.5 % incidence ) . Patients showed a preference for latanoprost for many systemic and ocular quality of life measures on a non-vali date d question naire ( p < 0.05 ) . Conclusions In a clinical setting , patients who have their mono- and adjunctive therapy treatment substituted for latanoprost may on average experience reduced IOP , deceased side effects and increased quality of life measures
The National Eye Institute Visual Function Question naire-25 , Impact of Vision Impairment and Treatment Satisfaction Survey-Intraocular Pressure had the highest number of positive ratings in the content validity assessment .
Conclusion This study provides a descriptive catalogue of vision-specific PRO instruments , to inform the choice of an appropriate measure of patient-reported outcomes in a glaucoma context
Purpose To identify  vision Patient-Reported Outcomes instruments relevant to glaucoma and assess their content validity .