Conclusion : Positive clinical ly meaningful effects ( > 5 points ) are seen to an age of 36 months , but are no longer present at 5 years
Objective : To determine in a systematic review , whether interventions for infant development that involve parents , improve neurodevelopment at 12 months corrected age or older .
Early intervention in low-birth-weight premature infants. Results through age 5 years from the Infant Health and Development Program.
OBJECTIVE To evaluate the persistence of effects on health and development at age 5 years of the Infant Health and Development Program , an early childhood intervention that was provided to low-birth-weight ( LBW ) premature infants from neonatal discharge through age 3 years . DESIGN R and omized , controlled , multicenter trial , stratified by two LBW groups : lighter ( < or = 2000 g ) and heavier ( 2001 to 2500 g ) . SETTING Eight socioeconomically heterogeneous clinical sites . PARTICIPANTS Of 985 eligible infants weighing 2500 g or less and at 37 weeks ' or less gestational age , 377 infants were r and omly assigned to the intervention group and 608 to the follow-up only group . About two thirds of the infants in each group were in the lighter LBW stratum , and one third were in the heavier LBW stratum . INTERVENTION The intervention group received home visits ( from neonatal discharge through age 3 years ) as well as center-based schooling ( from 1 to 3 years of age ) . Children in both groups received pediatric surveillance . MAIN OUTCOME MEASURES Cognitive development , behavioral competence , and health status . RESULTS At age 5 years , the intervention group had full-scale IQ scores similar to children in the follow-up only group . However , in the heavier LBW stratum , children in the intervention group had higher full-scale IQ scores ( 3.7 points higher ; P = .03 ) and higher verbal IQ scores ( 4.2 points higher ; P = .02 ) . No significant differences between intervention and follow-up only groups in cognitive measures at age 5 years were noted in the lighter LBW infants . The intervention and follow-up groups were similar in behavior and health measures regardless of LBW stratum . CONCLUSION The early childhood intervention provided in the first 3 years of life had effects on heavier LBW premature infants ' IQ and verbal performance at age 5 years that were not observed for lighter LBW premature infants . The intervention did not affect health or behavior at age 5 years in either LBW stratum
Conclusion : Positive clinical ly meaningful effects ( > 5 points ) are seen to an age of 36 months , but are no longer present at 5 years
Objective : To determine in a systematic review , whether interventions for infant development that involve parents , improve neurodevelopment at 12 months corrected age or older .