Results Prophylactic antibiotics  prevent inflammatory complications after gynaecological surgery .
Prophylactic antibiotics are more effective in surgery requiring access to the peritoneal cavity or the vagina .
Cefotetan appears to be more capable in preventing the overall inflammatory complication rate than cefoxitin or cefazolin .
No benefit has been shown for the combination of antibiotics as prophylaxis .
No difference has been shown between the long-term and short-term use of antibiotics .
There is no need for the primary use of an anaerobic antibacterial agent .
Conclusion Antibiotics help to prevent postoperative inflammatory complications after major gynecologic surgeries
Purpose The aim of this study was to systematic ally review the literature on antibiotic prophylaxis in gynaecologic surgeries to prevent inflammatory complications after gynaecological operations .
Oral trovafloxacin compared with intravenous cefoxitin in the prevention of bacterial infection after elective vaginal or abdominal hysterectomy for nonmalignant disease. Trovafloxacin Surgical Group.
BACKGROUND Trovafloxacin is a new fourth-generation fluoroquinolone whose pharmacokinetics and in vitro activity suggest that it is well suited for antibiotic prophylaxis in elective hysterectomy . METHODS In a r and omized , double-blind , multicenter study , parallel groups of women 18 years of age or older received either 200 mg trovafloxacin by mouth and intravenous ( i.v . ) placebo or 2 g cefoxitin by i.v . infusion and placebo by mouth before elective vaginal or abdominal hysterectomy for nonmalignant disease . RESULTS In the 103 and 97 patients in the trovafloxacin and cefoxitin groups , respectively , who were evaluable for efficacy , the prophylactic success rates at hospital discharge ( 96 % in both groups ) and 30 + /- 6 days after hysterectomy ( 88 % and 91 % in the trovafloxacin and cefoxitin groups , respectively ) were statistically equivalent . Both antibiotics were well tolerated . CONCLUSION A single oral 200 mg dose of trovafloxacin is as effective and safe as a st and ard cefoxitin parenteral regimen in the prevention of primary bacterial infection after elective vaginal or abdominal hysterectomy for nonmalignant disease
Results Prophylactic antibiotics  prevent inflammatory complications after gynaecological surgery .
Prophylactic antibiotics are more effective in surgery requiring access to the peritoneal cavity or the vagina .
Cefotetan appears to be more capable in preventing the overall inflammatory complication rate than cefoxitin or cefazolin .
No benefit has been shown for the combination of antibiotics as prophylaxis .
No difference has been shown between the long-term and short-term use of antibiotics .
There is no need for the primary use of an anaerobic antibacterial agent .
Conclusion Antibiotics help to prevent postoperative inflammatory complications after major gynecologic surgeries
Purpose The aim of this study was to systematic ally review the literature on antibiotic prophylaxis in gynaecologic surgeries to prevent inflammatory complications after gynaecological operations .