There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Infant nutrition and stereoacuity at age 4-6 y.
BACKGROUND Breastfeeding has been reported to benefit  visual development in children . A higher concentration of docosahexaneoic acid ( DHA ) in breast milk than in formula has been proposed as one explanation for this association and as a rationale for adding DHA to infant formula , but few long-term data support this possibility . OBJECTIVE The objectives of the study were , first , to test the hypothesis that breastfeeding benefits stereoscopic visual maturation and , second , if that benefit is shown , to ascertain whether it is mediated by the dietary intake of DHA . DESIGN Stereoacuity was measured by using the r and om dot E test ( primary outcome ) , and visual acuity was measured by using the Sonksen-Silver acuity system ( secondary outcome ) in previously breastfed ( n = 78 ) or formula-fed ( n = 184 ) children aged 4 - 6 y who had been followed prospect ively from birth . In the formula-fed group , children were r and omly assigned to receive formula with either DHA or arachidonic acid ( n = 94 ) or a control formula ( n = 90 ) for the first 6 mo . RESULTS Breastfed children had a significantly ( P = 0.001 ) greater likelihood of foveal stereoacuity ( high- grade or < 100 s/arc ) than did formula-fed children ( odds ratio : 2.5 ; 95 % CI : 1.4 , 4.5 ) independent of potential confounding ( P = 0.005 ) . Stereoacuity did not differ significantly between children r and omly assigned to DHA-supplemented or control formula . None of the groups differed in Sonksen-Silver visual acuity . CONCLUSIONS These findings support the hypothesis that breastfeeding benefits long-term stereoscopic development . An effect of DHA can not be excluded , but the lack of difference in stereoacuity between infants r and omly assigned to DHA-containing and those assigned to control formula raises the hypothesis that factors in breast milk other than DHA account for the observed benefits
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .