Conclusions : Pooled analyses show that barley β-glucan has a lowering effect on LDL-C and non-HDL-C. Inclusion of barley-containing foods may be a strategy for achieving targets in CVD risk reduction
Background / Objectives : There has been recent interest in barley as a therapeutic food owing to its high content of beta-glucan ( β-glucan ) , a viscous soluble fiber recognized for its cholesterol-lowering properties .
The objective of this study was to conduct a systematic review and meta- analysis of r and omized controlled trials ( RCTs ) investigating the cholesterol-lowering potential of barley β-glucan on low-density lipoprotein cholesterol ( LDL-C ) , non-high-density lipoprotein cholesterol ( non-HDL-C ) and apolipoprotein B ( apoB ) for cardiovascular disease ( CVD ) risk reduction .
Effect of high beta-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men--a randomized, double-blinded, placebo-controlled trial.
This study investigated whether the consumption of a diet in which high-beta-glucan barley replaced rice would reduce the visceral fat area as well as the serum low-density lipoprotein cholesterol ( LDL-C ) and total cholesterol ( TC ) in hypercholesterolemic Japanese men . A r and omized , double-blinded , placebo-controlled intervention study was conducted in 44 hypercholesterolemic Japanese men with a body mass index ( BMI ) > 22 kg/m2 . The subjects were r and omly assigned to groups consuming either rice ( placebo group ) or a mixture of rice and pearl barley with a high beta-glucan content ( test group , 7.0 g beta-glucan per day ) for 12 weeks . Blood sample s were taken , and CT scan obtained before the trial and every four weeks during the trial . The pearl barley intake significantly reduced serum concentrations of LDL-C ( P = 0.041 ) and TC ( P = 0.037 ) during the trial . Significant differences between the test and placebo groups were found for the visceral fat ( P = 0.039 ) , BMI ( P = 0.015 ) , and waist circumference ( P = 0.011 ) at the end point . The consumption of pearl barley with a high beta-glucan content reduces not only LDL-C but also visceral fat area
Conclusions : Pooled analyses show that barley β-glucan has a lowering effect on LDL-C and non-HDL-C. Inclusion of barley-containing foods may be a strategy for achieving targets in CVD risk reduction
Background / Objectives : There has been recent interest in barley as a therapeutic food owing to its high content of beta-glucan ( β-glucan ) , a viscous soluble fiber recognized for its cholesterol-lowering properties .
The objective of this study was to conduct a systematic review and meta- analysis of r and omized controlled trials ( RCTs ) investigating the cholesterol-lowering potential of barley β-glucan on low-density lipoprotein cholesterol ( LDL-C ) , non-high-density lipoprotein cholesterol ( non-HDL-C ) and apolipoprotein B ( apoB ) for cardiovascular disease ( CVD ) risk reduction .