Coconut oil consumption did not significantly affect markers of glycemia , inflammation , and adiposity as compared with nontropical vegetable oils .
Conclusions : Coconut oil consumption results in significantly higher LDL-cholesterol than nontropical vegetable oils .
Background : Coconut oil is high in saturated fat and may , therefore , raise serum cholesterol concentrations , but beneficial effects on other cardiovascular risk factors have also been suggested .
Therefore , we conducted a systematic review of the effect of coconut oil consumption on blood lipids and other cardiovascular risk factors compared with other cooking oils using data from clinical trials .
The effect of supplemental dietary fat on plasma cholesterol levels in lovastatin-treated hypercholesterolemic patients.
STUDY OBJECTIVE A validation study was conducted first to test assumptions about the effect of saturated and unsaturated dietary fat supplements . The second study was conducted to determine the effect on blood cholesterol levels of saturated and unsaturated fat supplements in patients who followed a low-fat diet and were administered lovastatin . DESIGN R and omized , crossover design , with three periods in the first study and four in the second study , each lasting 6 weeks . SETTING Cholesterol Research Center . PATIENTS The first study evaluated adults with total cholesterol levels between 200 and 280 mg/dl ( 5.172 and 7.241 mmol/L ) . The second study included adults with low-density lipoprotein ( LDL ) cholesterol levels above 160 mg/dl ( 4.138 mmol/L ) . INTERVENTIONS Fat supplements with either coconut or canola oil were delivered to patients in oatmeal-raisin cookies . MEASUREMENTS AND MAIN RESULTS In the validation study , patients ' mean prer and omization total cholesterol level of 222 mg/dl was reduced to 213 mg/dl with canola oil and increased to 233 mg/dl with coconut oil cookies ( p = 0.0038 ) . In the second study the mean prer and omization total cholesterol level of 214 mg/dl was decreased to 199 mg/dl with canola oil and to 208 mg/dl with coconut oil cookies ( p = 0.2342 ) . The LDL cholesterol levels changed in a similar fashion in both studies . CONCLUSIONS Changes in total and LDL cholesterol levels in the validation study were expected based on established effects of saturated and unsaturated fatty acids , but changes in these levels in lovastatin-cookie study were not expected . They could have occurred because lovastatin reversed the effect of saturated fats and enhanced the effect of unsaturated fats . Alternatively , they may have been due to enhanced bioavailability of lovastatin when administered with a high-fat diet . These findings must be confirmed
Coconut oil consumption did not significantly affect markers of glycemia , inflammation , and adiposity as compared with nontropical vegetable oils .
Conclusions : Coconut oil consumption results in significantly higher LDL-cholesterol than nontropical vegetable oils .
Background : Coconut oil is high in saturated fat and may , therefore , raise serum cholesterol concentrations , but beneficial effects on other cardiovascular risk factors have also been suggested .
Therefore , we conducted a systematic review of the effect of coconut oil consumption on blood lipids and other cardiovascular risk factors compared with other cooking oils using data from clinical trials .