The pooled estimate of efficacy of lactobacillus rhamnosus GG and other probiotics significantly reduced the duration of diarrhea .
In conclusion , probiotics exert positive effect in reducing the duration of acute rotavirus diarrhea  compared with control
BACKGROUND Probiotic therapies with different strains demonstrated some beneficial effects , although some studies did not show any significant effects .
This study assessed systematic ally the current knowledge on the effect of probiotic bacteria on duration of  acute rotavirus diarrhea in children compared with control .
Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial.
BACKGROUND The probiotic Lactobacillus GG is effective in promoting a more rapid recovery of acute , watery diarrhea in children with rotavirus enteritis . Very limited information is available , however , on the potential role of such agents in non-rotaviral diarrheal episodes . Furthermore , no evidence is available concerning the efficacy of Lactobacillus GG administered in the oral rehydration solution during oral rehydration therapy . A multicenter trial was conducted to evaluate the efficacy of Lactobacillus GG administered in the oral rehydration solution to patients with acute-onset diarrhea of all causes . METHODS Children 1 month to 3 years of age with acute-onset diarrhea were enrolled in a double-blind , placebo-controlled investigation . Patients were r and omly allocated to group A , receiving oral rehydration solution plus placebo , or group B , receiving the same preparation but with a live preparation of Lactobacillus GG ( at least 10(10 ) CFU/250 ml ) . After rehydration in the first 4 to 6 hours , patients were offered their usual feedings plus free access to the same solution until diarrhea stopped . RESULTS One hundred forty children were enrolled in group A , and 147 in group B. There were no differences at admission between the groups in age , sex , previous types of feeding , previous duration of diarrhea , use of antibiotics , weight , height , weight-height percentile , prevalence of fever , overall status , degree of dehydration , and percentage of in- versus out patients . Duration of diarrhea after enrollment was 71.9 + /- 35.8 hours in group A versus 58.3 + /- 27.6 hours in group B ( mean + /- SD ; P = 0.03 ) . In rotavirus-positive children , diarrhea lasted 76.6 + /- 41.6 hours in group A versus 56.2 + /- 16.9 hours in groups B ( P < 0.008 ) . Diarrhea lasted longer than 7 days in 10.7 % of group A versus 2.7 % of group B patients ( P < 0.01 ) . Hospital stays were significantly shorter in group B than in group A. CONCLUSIONS Administering oral rehydration solution containing Lactobacillus GG to children with acute diarrhea is safe and results in shorter duration of diarrhea , less chance of a protracted course , and faster discharge from the hospital
The pooled estimate of efficacy of lactobacillus rhamnosus GG and other probiotics significantly reduced the duration of diarrhea .
In conclusion , probiotics exert positive effect in reducing the duration of acute rotavirus diarrhea  compared with control
BACKGROUND Probiotic therapies with different strains demonstrated some beneficial effects , although some studies did not show any significant effects .
This study assessed systematic ally the current knowledge on the effect of probiotic bacteria on duration of  acute rotavirus diarrhea in children compared with control .