The systemic inflammatory response was normalized before or on the seventh postoperative day .
Conclusions Hernia repair elicits a systemic inflammatory response characterized by an increase in CRP , IL-6 , leukocytes , neutrophils , IL-1 , IL-10 , fibrinogen , and α1-antitrypsin and a decrease in lymphocytes and albumin .
A higher inflammatory response was found after mesh repair compared with non-mesh repair and after open mesh repair compared with laparoscopic mesh repair
Purpose All surgical procedures elicit a complex systemic inflammatory response effectuated and modulated by cytokines .
The purpose of this systematic review was to present an overview of the inflammatory response and the serum markers associated with hernia repair and to compare the response between patients treated with and without mesh .
Systemic stress responses after laparoscopic or open hernia repair.
OBJECTIVE To compare systemic stress responses after  laparoscopic  and  open hernia repair  to find out if the laparoscopic approach caused less stress than an open operation . DESIGN Prospect i ve r and omised trial . SETTING Teaching hospital , Sanliurfa , Turkey . SUBJECTS 50 patients who required preperitoneal hernia repair were r and omised to be treated by either the open or laparoscopic approach ( n = 25 in each ) . INTERVENTIONS Sample s of venous blood were taken before operation and at 2 , 24 , and 48 hours afterwards for measurement of the concentrations of : glucose , cortisol , malonyldialdehyde ( MDA ) , C-reactive protein ( CRP ) , creatine phosphokinase ( CPK ) , caeruloplasmin , transferrin , fibrinogen , and albumin , and counts of leucocytes , neutrophils , and lymphocytes . MAIN OUTCOME MEASURES Changes in these indicators of a stress response . RESULTS Concentrations of glucose , cortisol , CRP , MDA , and CPK , and counts of leucocytes and neutrophils increased significantly , and the concentration of albumin decreased significantly , in both groups postoperatively . Lymphocyte counts were lower postoperatively but not significantly so . Concentrations of CRP , MDA , and CPK , and leucocyte counts were significantly lower in the laparoscopic group . CONCLUSION These findings suggest that there is less systemic stress response after laparoscopic than after open hernia repair
The systemic inflammatory response was normalized before or on the seventh postoperative day .
Conclusions Hernia repair elicits a systemic inflammatory response characterized by an increase in CRP , IL-6 , leukocytes , neutrophils , IL-1 , IL-10 , fibrinogen , and α1-antitrypsin and a decrease in lymphocytes and albumin .
A higher inflammatory response was found after mesh repair compared with non-mesh repair and after open mesh repair compared with laparoscopic mesh repair
Purpose All surgical procedures elicit a complex systemic inflammatory response effectuated and modulated by cytokines .
The purpose of this systematic review was to present an overview of the inflammatory response and the serum markers associated with hernia repair and to compare the response between patients treated with and without mesh .