“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .
Effects of combined therapy of Xuezhikang Capsule (血脂康胶囊) and Valsartan on hypertensive left ventricular hypertrophy and heart rate turbulence
Objective To observe the effect of combined therapy with Xuezhikang Capsule ( 血脂康胶囊 , XZK ) and Valsartan on left ventricular hypertrophy ( LVH ) and heart rate turbulence ( HRT ) in hypertensive patients . Methods Ninety primary hypertensive patients with LVH were r and omly assigned to three groups . Basic treatment , including aspirin , β-blockers , calcium antagonists , etc . were administered to all patients . Additionally , Valsartan ( VS , 80 mg once a day ) was given to the 30 patients in the VS group . Valsartan ( in the same dosage ) and XZK ( 600 mg , twice a day ) were given to the 32 patients in the Chinese medicine ( CM ) group , while none was given to the 28 patients in the control group . The therapeutic course lasted for 24 months . Changes in left ventricular mass index ( LVMI ) measured by cardiac ultrasonic indices , HRT parameters , including the original heart rate ( TO ) and slope coeffificient ( TS ) , systolic and diastolic blood pressures ( SBP and DBP ) , as well as blood cholesterol level ( TC ) were measured before and after treatment . Results After treatment , TO and LVMI were lowered , while TS increased in both the VS group and the CM group ( P<0.01 ) , but changed insignificantly in the control group . Significant differences between the CM group and the control group were shown in terms of TO , LVMI , SBP , DBP and TS ( P<0.01 ) ; and between the CM group and the VS group in terms of TO , LVMI and TS ( P<0.01 ) . Moreover , HRT parameters showed an evident correlation with LVMI ( r=0.519–0.635 , P<0.01 ) . Conclusion Combined therapy with XZK and Valsartan can improve hypertensive LVH and HRT parameters , and lessen the damage on the autonomous nervous system
“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .