This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .
Intravenous Tenoxicam for Analgesia following Laparoscopic Cholecystectomy
In a double-blind , placebo-controlled clinical trial ( power of 80 % to detect a 30 % reduction in morphine consumption , P<0.05 ) we have determined that intraoperative intravenous administration of tenoxicam 40 mg during laparoscopic cholecystectomy , when compared with placebo , was associated with a significant reduction in consumption of morphine at 6 hours and 12 hours ( P<0.05 ) but not at 24 hours , when assessed by patient-controlled analgesia . Furthermore there was a significantly greater requirement for “ rescue ” analgesia with intramuscular morphine in the placebo group during the period of the study . There was no difference between the groups in pain scores , either at rest or on movement , nor in the incidence of nausea and vomiting . No patient in either group suffered a respiratory rate less than 8/min or oversedation at any time , and there were no other adverse effects
This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .