Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
Oat beta-glucan supplementation does not enhance the effectiveness of an energy-restricted diet in overweight women.
Epidemiological evidence shows an inverse relationship between dietary fibre intake and body weight gain .  Oat beta-glucan , a soluble fibre alters appetite hormones and subjective satiety in acute meal test studies , but its effects have not been demonstrated with chronic consumption . The present study aim ed to test the effects in women of two different doses of oat beta-glucan on weight loss and hormones associated with appetite regulation . In a 3-month parallel trial , sixty-six overweight females were r and omised into one of three 2 MJ energy-deficit diets : a control and two interventions including 5 - 6 g or 8 - 9 g beta-glucan .  Anthropometric and metabolic variables ( blood glucose level , insulin , total cholesterol ( TC ) , LDL , HDL , TAG and leptin ) , together with markers of appetite regulation ( cholecystokinin ( CCK ) , glucagon-like peptide-1 ( GLP-1 ) , ghrelin , peptide YY ( PYY ) and PYY3 - 36 ) were measured at baseline and at 3 months . After 3 months , all groups lost weight ( P < 0.001 ) and showed a reduced waist circumference ( P < 0.001 ) . The study sample also showed reductions in TC , LDL , HDL , leptin , PYY , GLP-1 values ( all P < 0.001 ) and an increase in CCK levels ( P < 0.001 ) . No significant differences were noted between the groups for all outcome values except PYY levels ( P = 0.018 ) . In broad terms , the addition of oat beta-glucan did not enhance the effect of energy restriction on weight loss in mildly overweight women , although wide variations in observed results suggests that individual responsiveness may be an issue
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .