Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Antimicrobial prophylaxis in laparoscopic and conventional cholecystectomy . Conclusions of a large prospective multicenter quality assurance study in Germany.
BACKGROUND Postoperative infection following cholecystectomy poses a significant threat to recovery , with major cost repercussions . Though antimicrobial prophylaxis is commonly practice d , its value - particularly in laparoscopic cholecystectomy - has not yet been adequately documented . METHOD In a prospect i ve multicenter quality assurance study in 28 German hospitals , an analysis of data collected on 4,477 patients undergoing conventional ( n = 1,349 ) or laparoscopic ( n = 3,128 ) cholecystectomy was performed ; 2,217 patients received and 2,260 did not obtain perioperative antibiotic cover .  RESULTS Postoperative infections occurred in a total of 136 patients , with infection rates of 5.0 % in those without prophylaxis , 0.8 % in those on ceftriaxone , and 1.2 % in those on other antibiotic regimens . Patients receiving prophylaxis fared significantly better than those with no prophylaxis in terms of the rate of postoperative wound infections , chest infections , other complications , reoperation and mortality . CONCLUSION Neither laparoscopic nor conventional open cholecystectomy should be performed without adequate perioperative antimicrobial prophylaxis in future , especially since such measures also reduce hospital stay and hence the costs
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .