This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
Calcium plus vitamin D supplementation affects pregnancy outcomes in gestational diabetes: randomized, double-blind, placebo-controlled trial.
OBJECTIVE The present study was design ed to assess the effects of Ca+vitamin D supplementation on pregnancy outcomes in women with gestational diabetes mellitus ( GDM ) . DESIGN A r and omized , double-blind , placebo-controlled trial was conducted among sixty women with GDM . Participants were divided into two groups to receive Ca+vitamin D supplements or placebo . Individuals in the Ca+vitamin D group ( n 30 ) received 1000 mg Ca/d and two pearls containing 1250 µg ( 50 000 IU ) of cholecalciferol ( vitamin D(3 ) ) during the intervention ( one at study baseline and another at day 21 of the intervention ) ; those in the placebo group ( n 30 ) received two placebos of vitamin D at the mentioned times and placebos of Ca every day for 6 weeks . Pregnancy outcomes were determined . SETTING A urban community setting in Arak , Iran . SUBJECTS Sixty women with GDM and their newborns , living in Arak , Iran were enrolled . RESULTS Women treated with Ca+vitamin D had a significant decrease in caesarean section rate ( 23·3 % v. 63·3 % , P=0·002 ) and maternal hospitalization ( 0 v. 13·3 % , P=0·03 ) compared with those receiving placebo . In addition , newborns of GDM women r and omized to Ca+vitamin D had no case of macrosomia , while the prevalence of macrosomia among those r and omized to placebo was 13·3 % ( P=0·03 ) . Lower rates of hyperbilirubinaemia ( 20·0 % v. 56·7 % , P=0·03 ) and hospitalization ( 20·0 % v. 56·7 % , P=0·03 ) were also seen in the supplemented group of newborns than in the placebo group . CONCLUSIONS Ca+vitamin D supplementation for 6 weeks among pregnant women with GDM led to decreased caesarean section rate and maternal hospitalization , and decreased macrosomia , hyperbilirubinaemia and hospitalization in newborns
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .