Summary Sedentary behaviour is associated with lower cognitive performance , although the attributable risk of sedentary time to all-cause dementia incidence is unclear .
Our systematic review provides evidence that limiting sedentary time and concomitantly engaging in regular moderate-to-vigorous physical activity may best promote healthy cognitive ageing
Aim The increasing rate of all-cause dementia worldwide and the lack of effective pharmaceutical treatments emphasise the value of lifestyle approaches as prevention strategies .
Emerging evidence suggests sedentary behaviour is associated with impaired cognitive function .
A better underst and ing of this association would significantly add to our knowledge of how to best promote healthy cognitive ageing .
Thus , we conducted a systematic review ascertaining the contribution of sedentary behaviour towards associated changes in cognitive function over the adult lifespan .
Memory evaluation with a new cued recall test in patients with mild cognitive impairment and Alzheimer’s disease
Free delayed recall is considered the memory measure with the greatest sensitivity for the early diagnosis of dementia . However , its specificity for dementia could be lower , as deficits other than those of pure memory might account for poor performance in this difficult and effortful task . Cued recall is supposed to allow a better distinction between poor memory due to concurrent factors and impairments related to the neurodegenerative process . The available cued recall tests suffer from a ceiling effect . This is a prospect i ve , longitudinal study aim ing to assess the utility of a new memory test based on cued recall that avoids the ceiling effect in the early diagnosis of Alzheimer ’s disease ( AD ) . Twenty-five patients with mild cognitive impairment ( MCI ) , 22 probable AD patients ( NINCDS-ADRDA ) at a mild stage , 22 elderly patients with subjective memory complaints ( SMC ) and 38 normal age-matched controls took part in the study . The patients underwent a thorough cognitive evaluation and the recommended screening procedure for the diagnosis of dementia . All patients were re-examined 12–18 months later . A newly devised delayed cued recall test using semantic cues ( The RI48 Test ) was compared with three established memory tests : the Ten Word-List Recall  from CERAD , the “ Doors ” and the “ Shapes ” Tests from “ The Doors and People Test Battery ” . Forty-four % of the MCI patients fulfilled criteria for probable AD at follow-up . The RI48 Test classified correctly 88 % of the MCI and SMC participants and was the best predictor of the status of MCI and mild AD as well as the outcome of the MCI patients . Poor visual memory was the second best predictor of those MCI patients who evolved to AD . A cued recall test which avoids the ceiling effect is at least as good as the delayed free recall tests in the early detection of AD
Summary Sedentary behaviour is associated with lower cognitive performance , although the attributable risk of sedentary time to all-cause dementia incidence is unclear .
Our systematic review provides evidence that limiting sedentary time and concomitantly engaging in regular moderate-to-vigorous physical activity may best promote healthy cognitive ageing
Aim The increasing rate of all-cause dementia worldwide and the lack of effective pharmaceutical treatments emphasise the value of lifestyle approaches as prevention strategies .
Emerging evidence suggests sedentary behaviour is associated with impaired cognitive function .
A better underst and ing of this association would significantly add to our knowledge of how to best promote healthy cognitive ageing .
Thus , we conducted a systematic review ascertaining the contribution of sedentary behaviour towards associated changes in cognitive function over the adult lifespan .