Conclusions Whole flaxseed , but not flaxseed oil and lignan extract , has significant effects on improving glycemic control .
Context The results of human clinical trials investigating the effects of flaxseed on glucose control and insulin sensitivity are inconsistent .
Objective The present study aim ed to systematic ally review and analyze r and omized controlled trials assessing the effects of flaxseed consumption on glycemic control .
The effect of flaxseed powder on insulin resistance indices and blood pressure in prediabetic individuals: A randomized controlled clinical trial
Background : Design ing the effective and early interventions can prevent progression of prediabetes to diabetes . Few studies have shown the effect of flaxseed on glycemic control . This study aim ed to assess the effect of flaxseed powder on insulin resistance ( IR ) indices and blood pressure in prediabetic individuals . Material s and Methods : In a r and omized clinical trial , 99 prediabetic individuals were r and omly divided into three groups : two groups received 40 g ( FG40 ) and 20 g ( FG20 ) flaxseed powder daily for 12 weeks and the third group was the control ( CG ) . Before and after the intervention , anthropometric measurements , blood pressure , fasting serum glucose ( FSG ) , insulin , homeostasis model assessment IR index ( HOMA-IR ) , beta-cell function , and insulin sensitivity were measured . Results : FSG significantly declined overall in all groups compared to the baseline ( P = 0.002 in CG and FG20 groups and P = 0.001 in FG40 ) . In contrast , mean of the changes in FSG was not significantly different between groups . Insulin concentration did not change significantly within and between the investigated groups . Although HOMA-IR reduced in FG20 ( P = 0.033 ) , the mean of changes was not significant between the three groups . Mean of beta-cell function increased in CG and FG40 groups compared to the baseline ( P = 0.044 and P = 0.018 , respectively ) , but mean of its changes did not show any difference between the three groups . The mean of changes in IR indices was not significant between the three groups . FG40 group had significantly lowered systolic blood pressure after the intervention ( P = 0.005 ) . Conclusion : Daily intake of flaxseed powder lowered blood pressure in prediabetes but did not improve glycemic and IR indices
Conclusions Whole flaxseed , but not flaxseed oil and lignan extract , has significant effects on improving glycemic control .
Context The results of human clinical trials investigating the effects of flaxseed on glucose control and insulin sensitivity are inconsistent .
Objective The present study aim ed to systematic ally review and analyze r and omized controlled trials assessing the effects of flaxseed consumption on glycemic control .