REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .
[Nifedipine in preeclampsia for cesarean section].
The patients with preeclampsia undergoing emergent cesarean section is always a challenge to an anesthesiologist , because severe hypertensive response after laryngoscopy and tracheal intubation may result in life-threatening complication such as cerebral hemorrhage . Most of these patients receive magnesium sulfate for the prevention of convulsion . An ideal anti-hypertensive drug for preeclampsia should be effective , limited fall in blood pressure , rapid onset , maintaining uteroplacental blood flow , and less maternal and fetal side effects . We studied the efficacy of 10 mg sublingual nifedipine in attenuating the pressor response to intubation . We were also concerned about whether this calcium antagonist may inhibit uterine contraction and increase intra and postpartum hemorrhage when it is used with magnesium sulfate and general anesthesia . There were thirty-three patients in our study ( 16 in nifedipine group and 17 in control group ) . This study revealed that nifedipine attenuate the hypertensive response effectively . Uterine contraction response to oxytocic drugs was quite well in both groups . There was no significant difference in blood loss between nifedipine and control group . And no severe maternal and fetal adverse effect
REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .