The most common concordant comorbidity was hypertension while depression was the most common discordant condition .
Adherence to medications was the most frequent diabetes self-care behavior reported and tended to be higher among concordant comorbidities .
The findings showed mixed results concerning the effect of some concordant comorbidities such as hypertension , hyperlipidemia , retinopathy , and heart failure on diabetes self-care behaviors .
But , there is agreement across studies that diabetes-discordant comorbidities have a more detrimental effect on self-care behaviors .
Conclusions : Concordant comorbidities may improve diabetes self-care , but the evidence is inconclusive .
Background : Most patients with Type 2 diabetes ( T2D ) have high number of comorbid chronic conditions that can affect their self-care abilities .
Guidelines for diabetes self-care behaviors are disease specific with little attention given to managing T2D with other comorbidities .
Identifying comorbidities that either improve or potentially diminish the individual 's capacity to perform effective self-care behaviors is essential to enhance clinical outcomes .
One such framework conceptualizes comorbidities as concordant or discordant with diabetes pathophysiological pathways and care goals .
Objective : The purpose of this systematic review was to examine the role of diabetes-concordant and discordant chronic conditions on the performance of self-care behaviors in adults with T2D .
Type 2 Diabetes: Demystifying the Global Epidemic
Type 2 diabetes ( T2D ) has attained the status of a global p and emic , spreading from affluent industrialized nations to the emerging economies of Asia , Latin America , and Africa . There is significant global variation in susceptibility to T2D , with Pacific Isl and ers , Asian Indians , and Native Americans being considerably more prone to develop the disorder . Although genetic factors may play a part , the rapidity with which diabetes prevalence has risen among these population s reflects the far-ranging and rapid socioeconomic changes to which they have been exposed over the past few decades . Traditionally , obesity and its correlate , insulin resistance , have been considered the major mediators of T2D risk ; however , recent evidence shows that early loss of β-cell function plays an important role in the pathogenesis of T2D , especially in nonobese individuals such as South Asians . Knowledge of the modifiable risk factors of T2D is important , as it forms the basis for design ing cost-effective preventive and therapeutic strategies to slow the epidemic in population s at increased risk . Lessons learned from r and omized prevention trials need to be implemented with appropriate cultural adaptations , accompanied by empowerment of the community , if the diabetes epidemic is to be slowed or halted
The most common concordant comorbidity was hypertension while depression was the most common discordant condition .
Adherence to medications was the most frequent diabetes self-care behavior reported and tended to be higher among concordant comorbidities .
The findings showed mixed results concerning the effect of some concordant comorbidities such as hypertension , hyperlipidemia , retinopathy , and heart failure on diabetes self-care behaviors .
But , there is agreement across studies that diabetes-discordant comorbidities have a more detrimental effect on self-care behaviors .
Conclusions : Concordant comorbidities may improve diabetes self-care , but the evidence is inconclusive .
Background : Most patients with Type 2 diabetes ( T2D ) have high number of comorbid chronic conditions that can affect their self-care abilities .
Guidelines for diabetes self-care behaviors are disease specific with little attention given to managing T2D with other comorbidities .
Identifying comorbidities that either improve or potentially diminish the individual 's capacity to perform effective self-care behaviors is essential to enhance clinical outcomes .
One such framework conceptualizes comorbidities as concordant or discordant with diabetes pathophysiological pathways and care goals .
Objective : The purpose of this systematic review was to examine the role of diabetes-concordant and discordant chronic conditions on the performance of self-care behaviors in adults with T2D .