Intensive glycaemic control does not seem to reduce all cause mortality in patients with type 2 diabetes .
OBJECTIVE To assess the effect of targeting intensive glycaemic control versus conventional glycaemic control on  all cause mortality and cardiovascular mortality , non-fatal myocardial infa rct ion , microvascular complications , and severe hypoglycaemia in patients with type 2 diabetes .
Effect of intravenous insulin administration on left ventricular performance during non-ST-elevation acute coronary events in patients with diabetes mellitus.
maintaining near-normal glycemia . 5 Group B patients were treated using the usual protocol s , with oral hy- poglycemic drugs or 2 daily doses of intermediate- acting insulin . Supplementary small doses of short- acting insulin were administered subcutaneously only if glucose levels were 250 mg/dl . Mean daily plasma glucose levels were assessed in each patient in both groups by employing all the measured glucose values obtained during the study . The mean glucose level in the conservative treatment group was assessed by the 3 st and ard prepr and ial glucose values ( at 7 A.M. , 1 P.M. , 6 P.M. ) , 1 measurement at 12 A.M. hours and any additional measurements that were performed accord- ing to the discretion of the attending physician . All patients were treated with an optimal antianginal reg- imen . Complete 2-dimensional , spectral , and color-fl ow Doppler echocardiographic examinations were per- formed by 2 examiners not involved in the fi nal anal- ysis of data , with a Hewlett-Packard Sonos 1000 Ul- trasound Machine ( And over , Massachusetts ) with a 2.5-MHz transducer , while the patients were asymp- tomatic . Images were obtained within 3 hours from ad- mission and 72 hours later and stored on high- quality videotapes for later blinded analysis . A DI design ed to determine the combined systolic and diastolic myocar- dial performance , and defi ned as the sum of isovolumet- ric contraction time plus isovolumetric relaxation time divided by ejection time , was estimated from LV outfl ow and mitral infl ow velocity patterns ( ( IVCT IVRT)/ ET).6 Videotape recordings were analyzed by 1
Intensive glycaemic control does not seem to reduce all cause mortality in patients with type 2 diabetes .
OBJECTIVE To assess the effect of targeting intensive glycaemic control versus conventional glycaemic control on  all cause mortality and cardiovascular mortality , non-fatal myocardial infa rct ion , microvascular complications , and severe hypoglycaemia in patients with type 2 diabetes .