This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
The effect of vitamin D supplementation on gestational diabetes in high-risk women: Results from a randomized placebo-controlled trial
Background : Vitamin D deficiency is common in pregnancy , leading to increase in the frequency of preeclampsia , cesarean delivery , neonatal bacterial vaginosis , and gestational diabetes . The current study was design ed and implemented to investigate the effect of vitamin D during the first and second trimesters of pregnancy in reducing the risk of gestational diabetes mellitus ( GDM )  in women who are at high risk [ history of GDM , birth macrosomia , family history , and high body mass index ( BMI ) ] . Material s and Methods : In a r and omized , double-blind , and placebo-controlled trial , 90 pregnant women who had at least one risk factor for GDM were r and omized into intervention ( 46 participants ) and control ( 44 participants ) groups . Participants in the intervention group took 5000 units of vitamin D daily and the control group took placebo until the 26th week of pregnancy . Then the  glucose challenge test  ( GCT ) and the  glucose tolerance test ( GTT ) were performed to evaluate GDM . Results : Mean ± st and ard deviation ( SD ) age was 31.28 ± 6.38 years and 29 ± 6.24 years for the intervention group and the placebo group , respectively , ( P > 0.05 ) . In addition , there were no significant differences between two groups in terms of vitamin D levels and GCT ( P > 0.05 ) , and the difference was not significant . The incidence of diabetes in the intervention groups was statistically lower than in control group ( 11.4 % vs 34.8 ; P < 0.01 ) . The results showed that abnormal GCT in the placebo group was statistically higher than in intervention group ( 35.9 % vs 10.9 P < 0.005 ) . Conclusion : The results of the current study showed that the prescription of vitamin D supplementation in the first and second trimesters of pregnancy was effective in reducing GDM and controlling GTT and GTC
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .