Results Prophylactic antibiotics  prevent inflammatory complications after gynaecological surgery .
Prophylactic antibiotics are more effective in surgery requiring access to the peritoneal cavity or the vagina .
Cefotetan appears to be more capable in preventing the overall inflammatory complication rate than cefoxitin or cefazolin .
No benefit has been shown for the combination of antibiotics as prophylaxis .
No difference has been shown between the long-term and short-term use of antibiotics .
There is no need for the primary use of an anaerobic antibacterial agent .
Conclusion Antibiotics help to prevent postoperative inflammatory complications after major gynecologic surgeries
Purpose The aim of this study was to systematic ally review the literature on antibiotic prophylaxis in gynaecologic surgeries to prevent inflammatory complications after gynaecological operations .
Amoxycillin/clavulanate prophylaxis in gynecologic surgery.
used as antibiotic prophylaxis in abdominal and gynecologic surgery being effective against most bacteria , including anaerobes w1,2x . Different reported protocol s of antibiotic prophylaxis tend to reduce doses and it is now usual to give a single administration before the start of the surgery w3x . To evaluate this concept , we compared the efficacy of a single preoperative dose of amoxycillinyclavulanate ( AyC ) with a two-dose administration , one 30 min before the operation and the other 8 h later . The study included 358 women admitted to our Department for surgery . Exclusion criteria were : allergy to the study drug , serious renal and yor hepatic diseases , antibiotic or corticosteroid treatment in the 14 days before surgery . Subjects were assigned r and omly to one of the two treatment groups : 190 patients received 2.2 g of AyC i.v . before surgery ( group 1 ) , while 168 patients received a second dose after 8 h ( group 2 ) . St and ard preoperative and postoperative assessment was carried out in all patients . All operations were performed by the same gynecologists . The subjects were divided according to : type of surgery
Results Prophylactic antibiotics  prevent inflammatory complications after gynaecological surgery .
Prophylactic antibiotics are more effective in surgery requiring access to the peritoneal cavity or the vagina .
Cefotetan appears to be more capable in preventing the overall inflammatory complication rate than cefoxitin or cefazolin .
No benefit has been shown for the combination of antibiotics as prophylaxis .
No difference has been shown between the long-term and short-term use of antibiotics .
There is no need for the primary use of an anaerobic antibacterial agent .
Conclusion Antibiotics help to prevent postoperative inflammatory complications after major gynecologic surgeries
Purpose The aim of this study was to systematic ally review the literature on antibiotic prophylaxis in gynaecologic surgeries to prevent inflammatory complications after gynaecological operations .