All eight domains were predictive for at least one of the investigated outcomes but the results were quite variable across studies .
Physical function and nutritional status were the domains most often associated with mortality and systemic treatment-related outcomes , and the domain physical function was most often associated with postoperative complications .
Overall , this review demonstrates that the GA should minimally consist of physical function and nutritional status , when the aim is to predict patients -related outcomes of older patients with cancer , although the results are quite heterogeneous .
BACKGROUND A geriatric assessment ( GA ) is increasingly used to help guide treatment decisions in older patients with cancer .
However , there is no consensus regarding which domains should be included in the GA .
In addition , the field of geriatric oncology moves very fast and as a result many new studies have been published since the last review in 2015 .
Therefore , the objective of this systematic review is to evaluate which domains of the GA could predict patient-related treatment outcomes of older patients with cancer and thereby should be included in a GA .
Prediction of Postoperative Complications Following Elective Surgery in Elderly Patients with Colorectal Cancer Using the Comprehensive Geriatric Assessment
Aims : The study aims to determine whether the Comprehensive Geriatric Assessment ( CGA ) could predict complications of colorectal cancer ( CRC ) surgery and identify the problems . So we compared the prognostic value of the CGA with patient characteristics and determined predictive scores . Methods : A total of 156 patients aged 75 years and older , who underwent surgery for CRC at Osaka University Hospital , were enrolled . Each patient was examined by the CGA prospect ively , and all postoperative complications were obtained from the medical records . The CGA included the  Barthel Index ( BI ) , Vitality Index , instrumental activities of daily living ( iADL ) , Mini-Mental State Examination ( MMSE ) and Geriatric Depression Score ( GDS ) .  All elements were retrospectively compared in patients with or without postoperative complications , including delirium , surgical site infection and ileus . Results : Overall , postoperative complications developed in 76 patients ( 48.7 % ) . The BI and MMSE were associated with the incidence of complications , and BI , iADL , MMSE and GDS were significantly related with delirium . Multivariate logistic analysis identified the MMSE as a significant determinant of postoperative complications after adjusting for other determined predictive scores including the prognostic nutritional index and performance status . Conclusion : The CGA was a useful predictor of postoperative complications in elderly patients when administered before surgery for CRC
All eight domains were predictive for at least one of the investigated outcomes but the results were quite variable across studies .
Physical function and nutritional status were the domains most often associated with mortality and systemic treatment-related outcomes , and the domain physical function was most often associated with postoperative complications .
Overall , this review demonstrates that the GA should minimally consist of physical function and nutritional status , when the aim is to predict patients -related outcomes of older patients with cancer , although the results are quite heterogeneous .
BACKGROUND A geriatric assessment ( GA ) is increasingly used to help guide treatment decisions in older patients with cancer .
However , there is no consensus regarding which domains should be included in the GA .
In addition , the field of geriatric oncology moves very fast and as a result many new studies have been published since the last review in 2015 .
Therefore , the objective of this systematic review is to evaluate which domains of the GA could predict patient-related treatment outcomes of older patients with cancer and thereby should be included in a GA .