On the CGI-I scale , the analysis revealed that MPH was more effective than ATX and GXR .
For any adverse events , RBX ( 89 % ) was the safest alternative .
Network meta- analysis offered a broader overview on the available treatments for ADHD , especially for safety issues , and contributes towards evidence gathering and clinical practice decisions .
The aim of this study is to gather evidence of head-to-head double-blind r and omized-controlled trials on the efficacy and safety of available treatments for attention deficit hyperactivity disorder ( ADHD ) in children and adolescents .
Caffeine versus methylphenidate and d-amphetamine in minimal brain dysfunction: a double-blind comparison.
The authors compared the efficacy of caffeine , methylpheni date , and d-amphetamine in children with minimal brain dysfunction using a double-blind crossover design . The slight improvement with caffeine was not significantly better than placebo . Both prescription drugs result ed in significant improvement and were significantly superior to caffeine . The authors suggest that the discrepancy between these results and an earlier , more optimistic report mat stem from the use in this study of pure caffeine rather than whole coffee
On the CGI-I scale , the analysis revealed that MPH was more effective than ATX and GXR .
For any adverse events , RBX ( 89 % ) was the safest alternative .
Network meta- analysis offered a broader overview on the available treatments for ADHD , especially for safety issues , and contributes towards evidence gathering and clinical practice decisions .
The aim of this study is to gather evidence of head-to-head double-blind r and omized-controlled trials on the efficacy and safety of available treatments for attention deficit hyperactivity disorder ( ADHD ) in children and adolescents .