The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile .
The mechanisms of action are still being studied .
ABSTRACT In this systematic review , we discuss the scientific evidence about the effect of dietary intake of seeds and sesame derivatives on lipid profile and blood pressure ( BP ) of hypertensive and dyslipidemic individuals .
Antihypertensive and antioxidant effects of dietary black sesame meal in pre-hypertensive humans
Background It has been known that hypertension is an independent risk factor for cardiovascular disease ( CVD ) . CVD is the major cause of morbidity and mortality in developed and developing countries . Elevation of blood pressure ( BP ) increases the adverse effect for cardiovascular outcomes . Prevention of increased BP plays a crucial role in a reduction of those outcomes , leading to a decrease in mortality . Therefore , the purpose of this study was to investigate the effects of dietary black sesame meal on BP and oxidative stress in individuals with prehypertension . Methods Twenty-two women and eight men ( aged 49.8 ± 6.6 years ) with prehypertension were r and omly divided into two groups , 15 subjects per group . They ingested 2.52 g black sesame meal capsules or placebo capsules each day for 4 weeks . Blood sample s were obtained after overnight fasting for measurement of plasma lipid , malondialdehyde ( MDA ) and vitamin E levels . Anthropometry , body composition and BP were measured before and after 4-week administration of black sesame meal or a placebo . Results The results showed that 4-week administration of black sesame meal significantly decreased systolic BP ( 129.3 ± 6.8 vs. 121.0 ± 9.0 mmHg , P < 0.05 ) and MDA level ( 1.8 ± 0.6 vs. 1.2 ± 0.6 μmol/L , P < 0.05 ) , and increased vitamin E level ( 29.4 ± 6.0 vs. 38.2 ± 7.8 μmol/L , P < 0.01 ) . In the black sesame meal group , the change in SBP tended to be positively related to the change in MDA ( R = 0.50 , P = 0.05 ) , while the change in DBP was negatively related to the change in vitamin E ( R = -0.55 , P < 0.05 ) . There were no correlations between changes in BP and oxidative stress in the control group . Conclusions These results suggest the possible antihypertensive effects of black sesame meal on improving antioxidant status and decreasing oxidant stress . These data may imply a beneficial effect of black sesame meal on prevention of CVD
The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile .
The mechanisms of action are still being studied .
ABSTRACT In this systematic review , we discuss the scientific evidence about the effect of dietary intake of seeds and sesame derivatives on lipid profile and blood pressure ( BP ) of hypertensive and dyslipidemic individuals .