Although most study - authors were positive , we could not draw firm conclusions about any of the pharmaceutical interventions .
Even patients that received placebo intervention showed improvement .
There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo .
Conclusions There is no evidence at all about the prevention of intertrigo and there is no firm evidence about its treatment .
Background Intertrigo in the large skin folds is a common problem .
There is a plethora of treatments , but a lack of evidence about their efficacy .
A nursing guideline on this matter had to be up date d and broadened in scope to other health care professionals .
[Evaluation of econazol in 594 cases of skin mycosis (author's transl)].
A total of 594 patients were treated with the new antimycotic agent econazol ( Pevaryl ) . The diagnosis was proven microscopically and on culture except in cases of pityriasis versicolor where it was proven microscopically only . Econazol was given to 130 patients as a 1 % solution , to 128 patients as a 1 % milk , and to 336 patients as a 1 % spray solution . In 333 cases of foot mycosis or eczema marginatum econazol spray powder was given in addition . As measured by the cure rate the spray solution ( 92 % ) was not significantly more effective than the milk ( 89 % ) or the simple solution ( 87 % ) . Criteria for cure included negative microscopy and fungal cultures a week after treatment had ceased as well as clinical cure . A total of 90 % of all cases ( n = 536 ) could be considered as cured microscopically and on culture after an average of 3.6 weeks ( pityriasis versicolor ) and 4.8 weeks ( tinea pedis , manus , inguinocruralis ) . In a further 4.4 % ( n = 26 ) the fungus could be demonstrated microscopically despite a clinical cure and in 7 of these cases culture was also positive . The cure rate was independent of the responsible pathogen . The preparations were tolerated extremely well . In 7 cases , however , transient dermatitic irritations were seen in the inguinocrural region , mainly caused by the simple solution
Although most study - authors were positive , we could not draw firm conclusions about any of the pharmaceutical interventions .
Even patients that received placebo intervention showed improvement .
There is weak evidence that reduction mammaplasty may be helpful to treat inframammary intertrigo .
Conclusions There is no evidence at all about the prevention of intertrigo and there is no firm evidence about its treatment .
Background Intertrigo in the large skin folds is a common problem .
There is a plethora of treatments , but a lack of evidence about their efficacy .
A nursing guideline on this matter had to be up date d and broadened in scope to other health care professionals .