The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .
Curcuminoids modulate pro-oxidant-antioxidant balance but not the immune response to heat shock protein 27 and oxidized LDL in obese individuals.
Curcuminoids have potentially important functional qualities including anti-inflammatory and antioxidant properties . In this r and omized double-blind placebo-controlled cross-over trial , the effects of a curcuminoid supplement on serum pro-oxidant-antioxidant balance ( PAB ) and antibody titres to Hsp27 ( anti-Hsp27 ) and oxLDL ( anti-oxLDL ) were investigated . Thirty obese individuals were r and omized to receive either curcuminoids ( 1 g/day ) or placebo for a period of 30 days . After a wash-out period of 2 weeks , subjects were crossed over to the alternate regimen for another 30 days . Serum PAB along with anti-Hsp27 and anti-oxLDL titres was measured at the beginning and at the end of each study period . There was no significant carry-over effect for any of the assessed parameters . Curcuminoid supplementation was associated with a significant decrease in PAB ( p = 0.044 ) . However , no significant change was observed in serum concentrations of anti-Hsp27 or anti-oxLDL ( p > 0.05 ) . These findings suggest that oral curcuminoids supplementation ( 1g/day ) is effective in reducing oxidative stress burden , though this needs to be vali date d in larger study population
The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .