Functional and cognitive impairment , depressive symptoms and social isolation are highly prevalent in head and neck cancer patients and associate with high risk of adverse health outcomes .
OBJECTIVES Older head and neck cancer patients are at increased risk for adverse health outcomes , but little is known about which geriatric assessment associates with poor outcome .
The aim is to study the association of functional or cognitive impairment , social environment and frailty with adverse health outcomes in patients with head and neck cancer .
Health-related quality of life as a survival predictor for patients with oral cancer: is quality of life associated with long-term overall survival?
OBJECTIVE The aim of the present prospect i ve study was to obtain further insight into health-related quality of life ( HR-QoL ) as a predictor of survival in a selected cohort of patients with oral cancer . STUDY DESIGN A total of 124 patients were treated with surgery or combined therapy .  All of the recruited patients completed the European Organization for Research and Treatment of Cancer question naires QLQC30 and H&N35 on 4 occasions . Overall survival was assessed . Univariate and multivariate Cox proportional hazards regression models were conducted . RESULTS High baseline HR-QoL score and high pain symptom score were significantly associated with a better survival ( HR 0.86 and 0.92 respectively ) . Swallowing ( HR 0.94 ) , and speech ( HR 0.92 ) high baseline scores were also significantly associated with a better survival in the adjusted analyses . CONCLUSIONS Patients who reported a better HR-QoL  at tumor diagnosis had a better survival than patients with a lower HR-QoL baseline score
Functional and cognitive impairment , depressive symptoms and social isolation are highly prevalent in head and neck cancer patients and associate with high risk of adverse health outcomes .
OBJECTIVES Older head and neck cancer patients are at increased risk for adverse health outcomes , but little is known about which geriatric assessment associates with poor outcome .
The aim is to study the association of functional or cognitive impairment , social environment and frailty with adverse health outcomes in patients with head and neck cancer .