Conclusions Compared to the placebo or manual reduction method , the topical steroid therapy is more effective in the treatment of phimosis in children .
Although there is still controversy in the different type and dosage of steroid , this could be used against phimosis before circumcision
Abstract Purpose We evaluated a systematic review on the therapeutic efficacy of topical steroids in children with phimosis to provide data for the clinical options of pediatric phimosis .
Topical steroid application versus circumcision in pediatric patients with phimosis: a prospective randomized placebo controlled clinical trial
Objectives Topical steroids have been advocated as an effective alternative treatment to circumcision in boys with phimosis . We evaluated the effectiveness of topical steroid therapy compared to a placebo neutral cream in 240 patients with phimosis . Methods A prospect i ve study was carried out over a 24-months period , on an out-patient basis on two groups of patients with phimosis . One-hundred twenty patients applied a steroid cream twice a day for 4 weeks , and another group of 120 pts used a placebo cream twice a day for 4 weeks . Patients were assigned to either group by a computer-generated r and om choice . Results All patients in our series completed the two treatment periods without interruption . At a median follow-up of 20 months ( 6–30 months ) therapeutic success was obtained in 43.75 % ( 99/240 ) of cases , independently of the protocol . In particular , therapeutic success was obtained in 65.8 % ( 79/120 ) of cases in the steroids group and in 16.6 % ( 20/120 ) of cases in the placebo group , the difference being statistically significant ( P < 0.0001 , Mann – Withney test ) . Conclusion Our study shows that topical steroids represent a good alternative to surgery in case of phimosis . Steroid therapy using monometasone furoate 0.1 % in our series gave better results that placebo with an overall efficacy of 65.8 % . In patients where a phimotic ring persist after steroid therapy , circumcision is m and atory
Conclusions Compared to the placebo or manual reduction method , the topical steroid therapy is more effective in the treatment of phimosis in children .
Although there is still controversy in the different type and dosage of steroid , this could be used against phimosis before circumcision
Abstract Purpose We evaluated a systematic review on the therapeutic efficacy of topical steroids in children with phimosis to provide data for the clinical options of pediatric phimosis .