Criterion validity for three of these measures was established in NSCLC but not the reliability or responsiveness .
Background The measurement properties of instruments used to assess functional capacity , physical activity and muscle strength in participants with non-small cell lung cancer ( NSCLC ) have not been systematic ally review ed .
Method Objectives : To identify outcome measures used to assess these outcomes in participants with NSCLC ; and to evaluate , synthesis e and compare the measurement properties of the outcome measures identified .
Preoperative assessment of the high-risk patient for lung resection.
BACKGROUND We wanted to determine if cardiopulmonary exercise testing could better identify the threshold where physiologic function is irreparably impaired for patients with borderline pulmonary function who are being considered for lung cancer resection . METHODS We performed an open , prospect i ve preoperative trial and a postoperative outcome evaluation with a combined medical , surgical , and exercise physiology evaluation at three university hospitals . All eligible patients had spirometry , lung volume determination , and quantitative perfusion scanning and performed a cardiopulmonary stress test , stair climbing , and a 12-minute walk for distance .  Functional status was determined with an Eastern Cooperative Oncology Group score , a dyspnea score , and a cardiopulmonary risk index . RESULTS We identified 12 patients who met strict criteria for borderline pulmonary function during a 1-year study period . The mean forced expiratory volume in 1 second ( FEV1 ) was 1.38 L ( 48 % of predicted ) . The mean predicted postoperative FEV1 based on pneumonectomy was 700 mL. Eleven of the patients did the stair climb and 10 passed . All 12 patients achieved a maximum oxygen consumption greater than or equal to 10 mL x kg(-1 ) x min(-1 ) ( mean value , 13.8 mL x kg(-1 ) x min(-1 ) ) . Thirteen operations were performed on the 12 patients . Nine complications occurred in 7 patients . CONCLUSIONS Patients with borderline pulmonary function can undergo resection safely if they have an FEV1 equal to or greater than 1.6 L or 40 % of its predicted value , a predicted postoperative FEV1 of 700 mL or more , a maximum oxygen consumption of 10 mL x kg(-1 ) x min(-1 ) or greater , or stair climbing of three flights or more . Cardiopulmonary stress testing and stair climbing add valuable clinical information for patients with an FEV1 of less than 1.6
Criterion validity for three of these measures was established in NSCLC but not the reliability or responsiveness .
Background The measurement properties of instruments used to assess functional capacity , physical activity and muscle strength in participants with non-small cell lung cancer ( NSCLC ) have not been systematic ally review ed .
Method Objectives : To identify outcome measures used to assess these outcomes in participants with NSCLC ; and to evaluate , synthesis e and compare the measurement properties of the outcome measures identified .