Findings were mixed and showed various effects of cannabinoid administration on several aspects of sleep .
This paper review s the literature regarding the effects of cannabinoid administration on  sleep in humans .
Dronabinol and Marijuana in HIV-Positive Marijuana Smokers: Caloric Intake, Mood, and Sleep
Objectives : Individuals with HIV constitute the largest group using cannabinoids for medicinal reasons ; yet , no studies have directly compared the tolerability and efficacy of smoked marijuana and oral dronabinol maintenance in HIV-positive marijuana smokers . This placebo-controlled within-subjects study evaluated marijuana and dronabinol across a range of behaviors : eating topography , mood , cognitive performance , physiologic measures , and sleep . Methods : HIV-positive marijuana smokers ( n = 10 ) completed 2 16-day inpatient phases . Each dronabinol ( 5 and 10 mg ) and marijuana ( 2.0 % and 3.9 % Δ9-tetrahydrocannabinol [ THC ] ) dose was administered 4 times daily for 4 days , but only 1 drug was active per day , thereby maintaining double-blind dosing . Four days of placebo washout separated each active cannabinoid condition . Results : As compared with placebo , marijuana and dronabinol dose dependently increased daily caloric intake and body weight in HIV-positive marijuana smokers . All cannabinoid conditions produced significant intoxication , except for low-dose dronabinol ( 5 mg ) ; the intoxication was rated positively ( eg , “ good drug effect ” ) with little evidence of discomfort and no impairment of cognitive performance . Effects of marijuana and dronabinol were comparable , except that only marijuana ( 3.9 % THC ) improved ratings of sleep . Conclusions : These data suggest that for HIV-positive marijuana smokers , both dronabinol ( at doses 8 times current recommendations ) and marijuana were well tolerated and produced substantial and comparable increases in food intake
Findings were mixed and showed various effects of cannabinoid administration on several aspects of sleep .
This paper review s the literature regarding the effects of cannabinoid administration on  sleep in humans .