Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .
Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial
Background Alternate day fasting ( ADF ; ad libitum “ feed day ” , alternated with 25 % energy intake “ fast day ” ) , is effective for weight loss and cardio-protection in obese individuals . Whether these effects occur in normal weight and overweight individuals remains unknown . This study examined the effect of ADF on body weight and coronary heart disease risk in non-obese subjects . Methods Thirty-two subjects ( BMI 20–29.9 kg/m2 ) were r and omized to either an ADF group or a control group for 12 weeks . Results Body weight decreased ( P < 0.001 ) by 5.2 ± 0.9 kg ( 6.5 ± 1.0 % ) in the ADF group , relative to the control group , by week 12 . Fat mass was reduced ( P < 0.001 ) by 3.6 ± 0.7 kg , and fat free mass did not change , versus controls . Triacylglycerol concentrations decreased ( 20 ± 8 % , P < 0.05 ) and LDL particle size increased ( 4 ± 1 Å , P < 0.01 ) in the ADF group relative to controls . CRP decreased ( 13 ± 17 % , P < 0.05 ) in the ADF group relative to controls at week 12 . Plasma adiponectin increased ( 6 ± 10 % , P < 0.01 ) while leptin decreased ( 40 ± 7 % , P < 0.05 ) in the ADF group versus controls by the end of the study . LDL cholesterol , HDL cholesterol , homocysteine and resistin concentrations remained unchanged after 12 weeks of treatment . Conclusion These findings suggest that ADF is effective for weight loss and cardio-protection in normal weight and overweight adults , though further research implementing larger sample sizes is required before solid conclusion can be reached
Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .