Overall , intervention groups obtained higher 25(OH)D concentration than controls and there was obvious dose – response effect between intake dose and 25(OH)D concentration .
Baseline 25(OH)D concentration and age were significant indicators for 25(OH)D concentration .
Conclusions Regional- and age-specific recommended dosages of VitD supplements for population to achieve optimal 25(OH)D concentrations have been suggested
Background / Objectives Optimal doses of vitamin D ( VitD ) supplement in different population s are unclear .
We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [ 25(OH)D ] concentration , to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different population s .
Resolving Vitamin D Deficiency in the Preconception Period among High-Risk Reproductive Women: A Randomized Controlled Trial
Background : Although vitamin D deficiency has been linked to potential complications in reproductive women , the recommended intake dosage of this vitamin in population s with high incidence of deficiency in preconception period has not been defined . Objectives : The study investigated the effect of consuming a dosage of 2000 IU/day oral vitamin D for 105 days , on serum levels of this vitamin in reproductive women . Material s and Methods : 229 women with 18 - 35 years old , who were confirmed to be vitamin D deficient ( vitamin D < 75 nmol/L ) , were r and omized into the intervention and control groups and after 15 weeks consumption of the supplement and placebo , their serum sample s were obtained . Results : At baseline the mean serum levels of vitamin D in the control group was 23.34 ± 15.87 nmol/L and in intervention group was 25.13 ± 18.46 nmol/L , that these values did n’t have any significant difference ( P = 0.43 ) , while after intervention , significant differences between the two groups was noticed ( P < 0.001 ) . The affecting factors to achieve normal range of vitamin D in the intervention group included basal amounts of vitamin D and two underlying factors based on question naire data : use of oral supplements ( except vitamin D and calcium ) in daily life and perfect sun exposure . Conclusion : This study showed positive effect of the 2000 IU/day oral vitamin D on the serum level elevation of this vitamin in reproductive women
Overall , intervention groups obtained higher 25(OH)D concentration than controls and there was obvious dose – response effect between intake dose and 25(OH)D concentration .
Baseline 25(OH)D concentration and age were significant indicators for 25(OH)D concentration .
Conclusions Regional- and age-specific recommended dosages of VitD supplements for population to achieve optimal 25(OH)D concentrations have been suggested
Background / Objectives Optimal doses of vitamin D ( VitD ) supplement in different population s are unclear .
We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [ 25(OH)D ] concentration , to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different population s .