None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .
The Effects of Glucose on Plasma Amino Acids and Pyruvate During Upper Abdominal Surgery
& NA ; To assess the potential benefits of perioperative glucose administration , the plasma concentrations of insulin , free fatty acids , ketone bodies , amino acids , lactate , and pyruvate were measured in 20 patients undergoing partial gastrectomy .  Ten patients received intravenous glucose at 10 g/h during the operation , and the other 10 patients , as control , received no glucose .  Plasma glucose , insulin activity , pyruvate and alanine concentrations in the glucose‐receiving group increased significantly during the operation in comparison with the control group . In contrast , in the glucose‐receiving group the plasma ketone bodies and branched‐chain amino acids , especially leucine and isoleucine , decreased significantly during surgery . These results suggest that administration of glucose stimulated insulin secretion and result ed in accumulation of the substrates such as pyruvate and alanine which were utilized readily in the body . Glucose administration is useful in suppressing catabolism during upper abdominal surgery . ( Anesth Analg 1993;76:357‐61
None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .