Conclusion : Probiotic treatment or supplementation is a promising therapeutic method for NAFLD
Background : Nonalcoholic fatty liver disease ( NAFLD ) has become prevalent in recent decades , especially in developed countries , and approaches for the prevention and treatment of NAFLD are not clear .
The aim of this research was to analyze and summarize r and omized controlled trials that investigated the effects of probiotics on NAFLD .
Adiposity in relation to risks of fatty liver, cirrhosis and liver cancer: a prospective study of 0.5 million Chinese adults
Adiposity is an increasing public health problem in China . We aim ed to examine the associations of adiposity with  non-alcoholic fatty liver disease ( NAFLD ) and other chronic liver diseases in Chinese adults . The prospect i ve China Kadoorie Biobank recruited 512,891 adults aged 30–79 years from 10 areas . During 10 years of follow-up , 7,386 incident liver disease cases were recorded among 503,991 participants without prior cancer or chronic liver disease at baseline . The mean body mass index ( BMI ) ( SD ) was 23.7 ( 3.3 ) kg/m2 and mean waist circumference ( WC ) 80.3 ( 9.8 ) cm , with 33 % having BMI ≥25 kg/m2 . Throughout the range examined ( BMI 15–50 ) BMI showed a log-linear positive association with NAFLD ( n = 1,298 ) , with adjusted HR per 5 kg/m2 of 2.81 ( 95 % CI 2.63–3.01 ) , adjusting for regression dilution . There were also positive associations of percent body fat , WC , and waist-to-hip ratio with NAFLD , with HRs per 1-SD of 2.27 ( 2.14–2.41 ) , 2.60 ( 2.44–2.76 ) , and 1.84 ( 1.76–1.92 ) . BMI was unrelated to viral hepatitis ( n = 1,477 ) , and had a U-shaped association with cirrhosis ( n = 2,082 ) and an inverse association with liver cancer ( n = 2,568 ) , which disappeared after excluding the first 5 years of follow-up . Among Chinese adults , adiposity was a major risk factor for NAFLD but not other chronic liver diseases
Conclusion : Probiotic treatment or supplementation is a promising therapeutic method for NAFLD
Background : Nonalcoholic fatty liver disease ( NAFLD ) has become prevalent in recent decades , especially in developed countries , and approaches for the prevention and treatment of NAFLD are not clear .
The aim of this research was to analyze and summarize r and omized controlled trials that investigated the effects of probiotics on NAFLD .