There was no significant difference between the groups in the studies regarding L-carnitina and flaxseed .
There is a lack of evidence regarding quality studies justifying the use of alternative products for weight loss
OBJECTIVE The high dem and for obesity treatment and conventional therapies ' lack of effectiveness increases the use of alternative products .
This study was aim ed at assessing evidence from r and omised clinical trials regarding the effectiveness of alternative weight-loss products ' ingredients .
Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans.
Alpha-linolenic acid ( ALA ) is a major dietary ( n-3 ) fatty acid . ALA is converted to longer-chain ( n-3 ) PUFA , such as eicosapentaenoic acid ( EPA ) and possibly docosahexaenoic acid ( DHA ) . EPA and DHA are fish-based ( n-3 ) fatty acids that have proven cardioprotective properties . We studied the effect of daily supplementation with 3 g of ALA on the plasma concentration of long-chain ( n-3 ) fatty acids in a predominantly African-American population with chronic illness . In a r and omized , double-blind trial , 56 participants were given 3 g ALA/d from flaxseed oil capsules ( n = 31 ) or olive oil placebo capsules ( n = 25 ) . Plasma EPA levels at 12 wk in the flaxseed oil group increased by 60 % , from 24.09 + /- 16.71 to 38.56 + /- 28.92 micromol/L ( P = 0.004 ) , whereas no change occurred in the olive oil group . Plasma docosapentaenoic acid ( DPA ) levels in the flaxseed oil group increased by 25 % from 19.94 + /- 9.22 to 27.03 + /- 17.17 micromol/L ( P = 0.03 ) with no change in the olive oil group . Plasma DHA levels did not change in either group . This study demonstrates the efficacy of the conversion of ALA to EPA and DPA in a minority population with chronic disease . ALA may be an alternative to fish oil ; however , additional clinical trials with ALA are warranted
There was no significant difference between the groups in the studies regarding L-carnitina and flaxseed .
There is a lack of evidence regarding quality studies justifying the use of alternative products for weight loss
OBJECTIVE The high dem and for obesity treatment and conventional therapies ' lack of effectiveness increases the use of alternative products .
This study was aim ed at assessing evidence from r and omised clinical trials regarding the effectiveness of alternative weight-loss products ' ingredients .