No significant difference was found between other treatments .
Conclusion Compared with antimuscarinic drugs , PTENS was associated with significant better efficacy considering MVV , but more constipation events in de novo OAB children .
Antimuscarinic drugs showed remarkably better efficacy considering MVV and comparable safety profile compared with urotherapy .
Objective To compare these managements focusing on the efficacy and safety to treat overactive bladder ( OAB ) in children through network meta- analysis ( NMA ) .
Parasacral transcutaneous electrical neural stimulation (PTENS) once a week for the treatment of overactive bladder in children: A randomized controlled trial.
INTRODUCTION Overactive bladder ( OAB ) is the most prevalent voiding disorder in childhood , and its main manifestation is urinary urgency . In general , urotherapy and anticholinergics are the first choices of treatment . Parasacral Transcutaneous Electrical Neural Stimulation ( PTENS ) was introduced as an alternative for the treatment of detrusor overactivity in children , but treatment protocol s described to date require several sessions per week or long-lasting sessions , making it difficult for the child to adhere to the treatment . Thus , this study aims to evaluate the effectiveness of PTENS in single weekly sessions in the treatment of OAB in children . STUDY DESIGN This prospect i ve , r and omized controlled trial included 16 children with OAB . Children were divided into two groups : CG ( urotherapy and electrical stimulation placebo ) and EG ( urotherapy and PTENS ) . For both groups , therapy was delivered in 20 weekly sessions , of duration 20 min each . Placebo electrical stimulation was done in the scapular area . The children were evaluated prior to treatment ( T1 ) , at the end of the 20 sessions ( T2 ) , and 60 days after the completion of treatment ( T3 ) , with a 3-day voiding diary , visual analogue scale ( VAS ) , Rome III diagnostic criteria , and the Bristol Scale . RESULTS The groups were similar in age , gender , and ethnicity . In the initial assessment , all children , in both groups , had urgency and incontinence , 50 % in each group had constipation , and enuresis was present in seven children ( 87.5 % ) in the EG and six ( 75 % ) in the CG . No differences were found between the groups regarding the volumetric measurements made in the voiding diary , urinary frequency and constipation evaluated by the Rome III criteria and the Bristol Scale . Sixty days after treatment , a significant improvement was found in the EG group ( p = 0.03 ) regarding urgency ( Table ) , as well as an increase in dry nights in those presenting with enuresis ( p = 0.03 ) . No difference was noted regarding urinary incontinence ( Table ) . At the end of 20 sessions and after 60 days of treatment , those responsible for the children in the EG perceived greater improvement in symptoms measured by the VAS ( p = 0.05 and 0.04 , respectively ) . CONCLUSIONS Our preliminary results demonstrate that PTENS performed in single weekly sessions is effective in treating the bladder for symptoms of urinary urgency and enuresis , and in the perception of those responsible for the children . Further studies with larger population s are needed to corroborate these results
No significant difference was found between other treatments .
Conclusion Compared with antimuscarinic drugs , PTENS was associated with significant better efficacy considering MVV , but more constipation events in de novo OAB children .
Antimuscarinic drugs showed remarkably better efficacy considering MVV and comparable safety profile compared with urotherapy .
Objective To compare these managements focusing on the efficacy and safety to treat overactive bladder ( OAB ) in children through network meta- analysis ( NMA ) .