The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride .
No difference was found when RM-GIC was compared with fluoride-containing composite resin .
RM-GIC showed efficacy in reducing demineralization .
UNLABELLED The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers ( RM-GIC ) , in comparison to fluoride-containing composite resin and composite resin without fluoride , are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge .
Extent of the cariostatic effect on root dentin provided by fluoride-containing restorative materials.
This study evaluated the extent of the cariostatic effect on root dentin provided by four fluoride-containing restorative systems : Ketac-Fil/ESPE [ Ke ] , Fuji II LC Improved/GC Corp [ Fj ] , Dyract AP/Dentsply [ Dy ] and SureFil/Dentsply [ Su ] , and one without fluoride : Z250/3 M [ control ] .  Ninety-five bovine root dentin fragments ( 5.0 x 6.0 mm ) were obtained , embedded in polyester resin and planed . Cavities ( 1.5 x 3.5 x 1.0 mm ) were made and restored by the five restorative systems ( n=19 ) in a r and omized complete block design according to the manufacturers ' instructions . After 24 hours , the dentin/restoration surface was polished . The restoration surface and an adjacent area of 3.0 x 3.0 mm were demarcated and su bmi tted to a pH-cycling model . Dentin surface Knoop microhardness values were obtained ( 5.0-g , 5.0-s ) for 10 distances : 50 , 100 , 150 , 300 , 600 , 900 , 1200 , 1500 , 1800 and 2100 microm from the margin of the restoration . The dentin microhardness means for each restorative material at each distance was considered by the ANOVA multi-factor split-plot method . The interaction between the restorative system and distance was statistically significant ( p<0.05 ) . The Tukey test and the regression analysis showed that the means of [ Ke ] and [ Fj ] were similar up to 300 microm , the [ Ke ] means being higher than the [ control ] at distances 50 , 100 , 150 and 300 microm . The [ Fj ] means were higher than the [ control ] at distances 50 , 100 and 150 microm . The microhardness means of [ Dy ] and [ Su ] were not statistically different from the [ control ] and remained steady throughout the studied distances . This study concluded that the extent of the cariostatic effect on root dentin was 300 microm for [ Ke ] and 150 microm for [ Fj ] . [ Dy ] and [ Su ] did not show any cariostatic effect
The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride .
No difference was found when RM-GIC was compared with fluoride-containing composite resin .
RM-GIC showed efficacy in reducing demineralization .
UNLABELLED The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers ( RM-GIC ) , in comparison to fluoride-containing composite resin and composite resin without fluoride , are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge .