Vitamin D in the form of vitamin D(3 ) seems to decrease mortality in predominantly elderly women who are mainly in institutions and dependent care .
Vitamin D(2 ) , alfacalcidol , and calcitriol had no statistically significant effect on mortality .
Vitamin D(3 ) combined with calcium significantly increased nephrolithiasis .
Both alfacalcidol and calcitriol significantly increased hypercalcaemia
BACKGROUND The available evidence on vitamin D and mortality is inconclusive .
OBJECTIVES To assess the beneficial and harmful effects of vitamin D for prevention of mortality in adults .
Vitamin D-Fortified Liquid Milk: Benefits for the Elderly Community-Based Population
Abstract . To assess the efficacy and acceptability of vitamin D-fortified liquid milk in the management of hypovitaminosis D we carried out a double-blind , r and omized , controlled trial on 51 community-based , elderly subjects with serum 25 hydroxyvitamin D ( 25OHD ) levels of less than 12.9 ng/ml ( normal range 10–80 ng/ml ) . Each subject had a dietary assessment , mental test score , outdoor score , serum 25 hydroxyvitamin D level , and a general biochemical screening at baseline in April 1993 which was repeated in September 1993 , April 1994 , and September 1994 . All subjects received 500 ml of milk per day , delivered to their homes in specially manufactured , blank , tetrapak cartons , from June 1993 to June 1994 : 23 subjects received unfortified milk ( control group ) and 28 subjects received fortified milk ( active group ) . Our results showed a baseline mean 25OHD level in the active group of 9.6 ( range < 5.5–12.7 ) ng/ml and in the control group of 10.0 ( range < 5.5–12.9 ) ng/ml ( P < 0.4 ) . One year later the mean 25OHD level in the active group had risen significantly from its baseline to 18.5 ( range 9.6–26.7 ) ng/ml ( P < 0.001 ) and was significantly different from the control group with a 1-year mean of 12.7 ( range < 4–24.1 ) ng/ml ( P < 0.001 ) . Serum calcium levels in the active group also showed a significant rise over the 1-year period ( P < 0.001 ) whereas those in the control group did not . We conclude that vitamin D-fortified liquid milk is a safe , effective , and acceptable method of administering vitamin D to the elderly , community-based population
Vitamin D in the form of vitamin D(3 ) seems to decrease mortality in predominantly elderly women who are mainly in institutions and dependent care .
Vitamin D(2 ) , alfacalcidol , and calcitriol had no statistically significant effect on mortality .
Vitamin D(3 ) combined with calcium significantly increased nephrolithiasis .
Both alfacalcidol and calcitriol significantly increased hypercalcaemia
BACKGROUND The available evidence on vitamin D and mortality is inconclusive .
OBJECTIVES To assess the beneficial and harmful effects of vitamin D for prevention of mortality in adults .