For blood glucose there was little difference between groups at any time point .
Objective Type 1 diabetes mellitus rates are rising worldwide .
The health benefits of physical exercise in this condition are many , but more than 60 % do not participate , mainly from fear of hypoglycemia .
This systematic review explores the effects of physical exercise modes on blood glucose levels in adults for hypoglycemia prevention .
Effects of exercise on the absorption of insulin glargine in patients with type 1 diabetes.
OBJECTIVE To study the effects of exercise on the absorption of the basal long-acting insulin analog insulin glargine ( Lantus ) , administered subcutaneously in individuals with type 1 diabetes . RESEARCH DESIGN AND METHODS A total of 13 patients ( 12 men , 1 woman ) with type 1 diabetes on a basal-bolus insulin regimen were studied .  (125)I-labeled insulin glargine at the usual basal insulin dose was injected subcutaneously into the thigh on the evening ( 2100 ) before the study day on two occasions 1 week apart . Patients were r and omly assigned to 30 min intense exercise ( 65 % peak oxygen uptake [ Vo(2peak ) ] ) on one of these visits . The decay of radioactive insulin glargine was compared on the two occasions using a thallium-activated Nal gamma counter . Blood sample s were collected at regular intervals on the study days to assess plasma glucose and insulin profiles . RESULTS No significant difference was found in the (125)I-labeled insulin glargine decay rate on the two occasions ( exercise vs. no exercise ; repeated- measures ANOVA , P = 0.548 ) . As expected , a significant fall in plasma glucose was observed over the exercise period ( area under curve above fasting [ DeltaAUC ] glucose : -0.39 + /- 0.11 vs. -1.30 + /- 0.16 mmol . l(-1 ) . h(-1 ) ; nonexercise vs. exercise ; P = 0.001 ) , but insulin levels did not differ significantly on the two occasions ( DeltaAUC insulin : -2.1 + /- 3.9 vs. 1.5 + /- 6.2 pmol . l(-1 ) . h(-1 ) ; nonexercise versus exercise ; P = 0.507 ) . CONCLUSIONS An intense 30-min period of exercise does not increase the absorption rate of the subcutaneously injected basal long-acting insulin analog insulin glargine in patients with type 1 diabetes
For blood glucose there was little difference between groups at any time point .
Objective Type 1 diabetes mellitus rates are rising worldwide .
The health benefits of physical exercise in this condition are many , but more than 60 % do not participate , mainly from fear of hypoglycemia .
This systematic review explores the effects of physical exercise modes on blood glucose levels in adults for hypoglycemia prevention .