Conclusions The current evidence is not sufficiently strong to verify a preventive role of probiotics in AR , but probiotics may improve the overall quality of life and nasal symptom scores .
Background Allergic rhinitis ( AR ) is a disease of respiratory allergy , and probiotics can provide a potential strategy for its management .
The purpose of this study was to carry out a systematic review to investigate the role of probiotics in the prevention and treatment of AR .
Enhancement of the Circulating Antibody Secreting Cell Response in Human Diarrhea by a Human Lactobacillus Strain
ABSTRACT : Human Lactobacillus sp strain GG ( Lactobacillus GG ) administered during acute rotavirus diarrhea has been shown to promote clinical recovery . To eluci date the immune mechanisms behind such a favorable outcome , the ELISPOT ( solid phase enzyme-linked immunospot ) assay of Ig- and specific antibody-secreting cells among circulating lymphocytes was used , giving indirect evidence of the immunologic events in the gut . After rehydration , 39 children with acute rotavirus diarrhea , mean age 16 ( SD 6 ) mo , r and omly received either a Lactobacillus GG fermented milk product ( study group ) or a pasteurized yogurt ( placebo group ) . The duration of diarrhea was significantly shorter in the study group than in the placebo group [ mean 1.1 ( SD 0.6 ) versus 2.5 ( SD 1.4 ) d , p = 0.001 ] . Lactobacillus GG therapy was associated with a significantly enhanced nonspecific humoral response during the acute phase of the infection , reflected in the IgG , IgA , and IgM Ig-secreting cell numbers . At convalescence , 90 % of the study group versus 46 % of the placebo group had developed an IgA specific antibody-secreting cell response to rotavirus ( p = 0.006 ) . The results indicate that Lactobacillus GG promotes recovery from rotavirus diarrhea via augmentation of the local immune defense . Furthermore , specific IgA response to rotavirus is endorsed , which is possibly relevant in protection against reinfections
Conclusions The current evidence is not sufficiently strong to verify a preventive role of probiotics in AR , but probiotics may improve the overall quality of life and nasal symptom scores .
Background Allergic rhinitis ( AR ) is a disease of respiratory allergy , and probiotics can provide a potential strategy for its management .
The purpose of this study was to carry out a systematic review to investigate the role of probiotics in the prevention and treatment of AR .