Exercise , particularly aerobic exercise , had a significant effect on serum leptin and a possible influence on adiponectin levels , suggesting its therapeutic implication
Previous reports have shown that exercise improves serum leptin and adiponectin abnormalities in overweight and obese individuals ; however , results to date are controversial .
Here we performed a systematic review and meta- analysis of the available r and omized controlled trials ( RCTs ) of the possible beneficial action of exercise on serum leptin and adiponectin levels in overweight and obese individuals .
Effects of short-term lifestyle activity modification on adiponectin mRNA expression and plasma concentrations
Abstract Adiponectin mRNA and plasma concentrations were reduced in obesity .  Exercise training may reduce the adipose tissue ( AT ) , although it is not well known , whether exercise – induced change in AT , increases adiponectin mRNA expression and plasma concentrations or not . Therefore , the purpose of this study was to examine the effects of short-term lifestyle activity modification ( LAM ) on adiponectin mRNA and plasma concentrations . Sixteen obese and overweight middle-aged men ( age , 35–50 years ) with type 2 diabetes participated in this study . The subjects were r and omly assigned to LAM group ( n=8 ) or control group ( n=8 ) . The subjects in LAM group walked two miles in 30 min on a treadmill on 4 days per week for 12 weeks according to the guidelines of the Centers for Disease Control and Prevention and American College of Sports Medicine . The results showed that body mass , body mass index , central visceral adipose tissue and subcutaneous adipose tissue volume and hip and thigh subcutaneous adipose tissue ( hip and thigh SAT ) volume were decreased in the LAM group compared to the control group ( P<0.05 ) . Adiponectin mRNA in abdominal and gluteal subcutaneous AT were increased significantly in the LAM group compared to the control group ( P<0.05 ) , while plasma adiponectin concentrations , hs-CRP and insulin resistance did not change significantly . In conclusion , adiponectin mRNA levels increase after 12 weeks of LAM ; however , plasma adiponectin levels were not affected by this protocol in obese and overweight middle-aged men with type 2 diabetes
Exercise , particularly aerobic exercise , had a significant effect on serum leptin and a possible influence on adiponectin levels , suggesting its therapeutic implication
Previous reports have shown that exercise improves serum leptin and adiponectin abnormalities in overweight and obese individuals ; however , results to date are controversial .
Here we performed a systematic review and meta- analysis of the available r and omized controlled trials ( RCTs ) of the possible beneficial action of exercise on serum leptin and adiponectin levels in overweight and obese individuals .