Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
The consumption of bread enriched with betaglucan reduces LDL-cholesterol and improves insulin resistance in patients with type 2 diabetes.
AIM Previous studies have shown that the water-soluble dietary fibre betaglucan , a natural component of oats , reduces cholesterol and postpr and ial hyperglycaemia . The aim of the present study was to investigate the effect of betaglucan-enriched bread consumption on the lipid profile and glucose homoeostasis of patients with type 2 diabetes ( T2D ) . METHODS We conducted a r and omized , double-blind study in which 46 patients with T2D and LDL-C greater than 3.37 mmol/l ( 130 mg/dl ) were r and omized to incorporate into their diet , for 3 weeks , either bread enriched with betaglucan ( providing 3g/day of betaglucan ) or white bread without betaglucan . RESULTS The consumption of bread containing betaglucan led to significant reductions ( vs the control group ) in LDL-C of 0.66 mmol/l ( 15.79 % ) versus 0.11 mmol/l ( 2.71 % ) ( P=0.009 ) , in total cholesterol of 0.80 mmol/l ( 12.80 % ) versus 0.12 mmol/l ( 1.88 % ) ( P=0.006 ) , in Fasting plasma insulin ( FPI ) of 3.23 microU/ml versus an increase of 3.77 microU/ml ( P=0.03 ) and in Homa-IR ( Homoeostasis model assessment -insulin resistance ) by 2.08 versus an increase of 1.33 ( P=0.04 ) . CONCLUSIONS Betaglucan enriched bread may contribute to the improvement of the lipid profile and insulin resistance in patients with T2D
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .