The current meta- analysis revealed that probiotic supplementation may result in increasing TAC and lowering MDA , which improve antioxidant status .
Previous studies have supposed that probiotic supplementation led to a positive effect on different health outcomes .
Furthermore , several studies indicated that probiotics supplementation improved antioxidant status , while some studies did not indicate these effects .
Hence , current systematic review and meta- analysis study was conducted to determine the effect of probiotic supplementation on some oxidative stress biomarkers  among adult subjects .
Ascorbic acid in bronchial asthma.
Sixteen White children with bronchial asthma were divided into two groups ; one received st and ard anti-asthma chemoprophylaxis ( SAC ) and the other SAC supplemented with 1 g ascorbic acid ( Redoxon ) given as a single daily dose for a 6-month period . In 10 patients the effects of ascorbic acid on exercise-induced bronchoconstriction ( EIB ) were assessed by comparing the pre-ascorbic acid results with those obtained 2 1/2 hours after the intravenous injection of 1 g ascorbic acid . Immunological investigations performed on the two groups were assessment of polymorphonuclear leucocyte ( PMNL ) motility , phagocytosis and nitroblue tetrazolium reduction and measurement of secretory IgA , serum immunoglobulin and total haemolytic complement levels and levels of the components C3 and C4 , alpha 1-antitrypsin , antistreptolysin O ( ASO ) , C-reactive protein and antibodies to certain respiratory viruses . These investigations were performed before and 1 , 3 and 6 months after the commencement of therapy . Radio-allergosorbent testing for sensitivity to four common allergens was carried out at the outset and after 6 months of therapy . Injection of ascorbic acid had no detectable effects on the degree of EIB . Slight but not significant immunological changes were observed in the SAC group over the 6-month study period . However , in the SAC plus ascorbic acid group significantly improved PMNL motility and decreased ASO levels and reduced ( although not to a significant extent ) IgE levels and titres of antibodies to the respiratory viruses were observed
The current meta- analysis revealed that probiotic supplementation may result in increasing TAC and lowering MDA , which improve antioxidant status .
Previous studies have supposed that probiotic supplementation led to a positive effect on different health outcomes .
Furthermore , several studies indicated that probiotics supplementation improved antioxidant status , while some studies did not indicate these effects .
Hence , current systematic review and meta- analysis study was conducted to determine the effect of probiotic supplementation on some oxidative stress biomarkers  among adult subjects .