RESULTS The present study indicated that the efficacy of various fiber supplements on losing weight is variable .
Several mechanisms related to physicochemical properties of fibers such as solubility , fermentability and viscosity rates can be involved in their anti-obesity effects .
Dextrin , Mannan ( gum Arabic ) and pectin-rich fiber ( lupin kernel ) with no dietary interventions indicated a reduction in body weight and energy intake , while from clinical point of view , their effects were not considerable .
Overall , findings indicated that the efficacy of fiber supplements on obesity management is dependent on their contents and physicochemical properties .
It seems that fiber supplements with no weight-loss interventions did not have considerable antiobesity effects .
BACKGROUND Previous trials have reported beneficial effects of isolated and complex fiber supplements in obesity treatment .
However , recommending fiber supplements in obese subjects remains controversial .
To the best of our knowledge , no systematic review has up date d the data on the effects of fiber supplements on obesity since 2010 and the need exists for a systematic review on this topic .
Accordingly , a systematic review was undertaken to summarize the efficacy of different types of fiber supplements as a complementary treatment for weight management .
Yeast β–Glucan Modulates Inflammation and Waist Circumference in Overweight and Obese Subjects
ABSTRACT Increased inflammation occurs with excessive adiposity and yeast β-glucan modulates immune responses . This study investigated the potential effect of yeast β-glucan on inflammatory cytokines in overweight/obese people . A r and omized , double blinded , placebo-controlled , clinical trial design enrolled 44 overweight/obese participants with body mass index ≥23 kg/m2 , r and omized to two groups  receiving β – glucan 477 mg/capsule ( n = 22 ) or placebo ( n = 22 ) orally for six weeks . At weeks one to two , participants received 1 β – glucan or placebo capsule/day and at four weeks two tablets/day . Anthropometric changes , lipid profiles , liver and renal functions , and inflammatory cytokines were measured . β-glucan  reduced waist circumference ( p = 0.037 ) and blood pressure ( p = 0.006 ) compared with controls after six weeks of intervention . No statistical significance between groups was observed for triglyceride , cholesterol , lipid profile , liver and renal function , or energy and nutrient intake compared with controls at week six . β-glucan increased interlukin-10 ( IL-10 ) , an anti-inflammatory cytokine , by 23.97 % from baseline at week two ( p < 0.001 ) and 31.12 % at week six ( p < 0.001 ) and was significantly increased compared with controls at week two ( p < 0.001 ) until week six ( p < 0.001 ) . β-glucan reduced pro-inflammatory cytokines IL-6 at week six ( p = 0.005 ) and tumor necrosis factor-α at week two ( p = 0.037 ) compared with controls . Supplementation of yeast β-glucan for six weeks modulated pro-cytokines that accelerate overweight/obese comorbidities and reduced blood pressure as well as waist circumference , the strong risk factors for cardiovascular disease , in overweight/obese subjects .  Thus , β-glucan might have the potential to decrease comorbid conditions associated with overweight/ obesity
RESULTS The present study indicated that the efficacy of various fiber supplements on losing weight is variable .
Several mechanisms related to physicochemical properties of fibers such as solubility , fermentability and viscosity rates can be involved in their anti-obesity effects .
Dextrin , Mannan ( gum Arabic ) and pectin-rich fiber ( lupin kernel ) with no dietary interventions indicated a reduction in body weight and energy intake , while from clinical point of view , their effects were not considerable .
Overall , findings indicated that the efficacy of fiber supplements on obesity management is dependent on their contents and physicochemical properties .
It seems that fiber supplements with no weight-loss interventions did not have considerable antiobesity effects .
BACKGROUND Previous trials have reported beneficial effects of isolated and complex fiber supplements in obesity treatment .
However , recommending fiber supplements in obese subjects remains controversial .
To the best of our knowledge , no systematic review has up date d the data on the effects of fiber supplements on obesity since 2010 and the need exists for a systematic review on this topic .
Accordingly , a systematic review was undertaken to summarize the efficacy of different types of fiber supplements as a complementary treatment for weight management .