REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .
Clonidine Hydrochloride—A Safe and Effective Antihypertensive Agent in Pregnancy
A prospect i ve , double-blind , r and omized controlled trial was carried out , comparing α-methyldopa and clonidine hydrochloride in 100 pregnant women with hypertension . There was no difference in hypotensive effect or reported maternal side effects with either agent . There was one neonatal loss in each group ( 98 % survival ) . Neither drug caused clinical ly significant hypotension nor rebound hypertension in the neonates . Clonidine hydrochloride , like methyldopa , appears to be a safe antihypertensive agent in pregnancy
REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .