Results showed no significant effects on core symptomatology .
In conclusion , up to date , evidence regarding the potential utility of IN-OT in treating anxiety and depression is still inconclusive .
Several studies have demonstrated the neuromodulating function of oxytocin ( OT ) in response to anxiogenic stimuli as well as its potential role in the pathogenesis of depression .
Consequently , intranasal OT ( IN-OT ) has been proposed as a potential treatment of  anxiety and depressive disorders .
The present systematic review aim ed to summarize the r and omized controlled trials ( RCTs ) evaluating the effect of IN-OT on anxiety and depressive symptoms .
Something to talk about: Gossip increases oxytocin levels in a near real-life situation
Gossip is a pervasive social behavior . Its evolutionary survival seems related to its social functions , such as establishing group rules , punishing trespassers , exercising social influence through reputational systems , and developing and strengthening social bonds . We aim ed at evaluating the effect of gossip on hormones ( oxytocin and cortisol ) and at identifying potential mediators of hormonal response to gossip . Twenty-two female students were r and omly assigned to a  gossip conversation  or to an emotional non-gossip conversation .  Additionally , all participants underwent a neutral conversation on the second day of the study . Salivary oxytocin and cortisol levels were measured . Oxytocin increased significantly in the gossip compared to the emotional non-gossip conversation . A decrease in cortisol levels was observed in all three conditions ( gossip , emotional non-gossip , neutral ) . Change in cortisol levels was similar across conditions . Psychological characteristics ( e.g. empathy , autistic traits , perceived stress , envy ) did not affect oxytocin rise in the gossip condition . Our findings suggest that oxytocin may represent a potential hormonal correlate of gossip behavior
Results showed no significant effects on core symptomatology .
In conclusion , up to date , evidence regarding the potential utility of IN-OT in treating anxiety and depression is still inconclusive .
Several studies have demonstrated the neuromodulating function of oxytocin ( OT ) in response to anxiogenic stimuli as well as its potential role in the pathogenesis of depression .
Consequently , intranasal OT ( IN-OT ) has been proposed as a potential treatment of  anxiety and depressive disorders .
The present systematic review aim ed to summarize the r and omized controlled trials ( RCTs ) evaluating the effect of IN-OT on anxiety and depressive symptoms .