There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .
An increase in dietary protein improves the blood glucose response in persons with type 2 diabetes.
BACKGROUND In single-meal studies , dietary protein does not result in an increase in glucose concentrations in persons with or without type 2 diabetes , even though the result ing amino acids can be used for gluconeogenesis . OBJECTIVE The metabolic effects of a high-protein diet were compared with those of the prototypical healthy ( control ) diet , which is currently recommended by several scientific organizations . DESIGN The metabolic effects of both diets , consumed for 5 wk each ( separated by a 2 - 5-wk washout period ) , were studied in 12 subjects with untreated type 2 diabetes . The ratio of protein to carbohydrate to fat was 30:40:30 in the high-protein diet and 15:55:30 in the control diet . The subjects remained weight-stable during the study . RESULTS With the fasting glucose concentration used as a baseline from which to determine the area under the curve , the high-protein diet result ed in a 40 % decrease in the mean 24-h integrated glucose area response . Glycated hemoglobin decreased 0.8 % and 0.3 % after 5 wk of the high-protein and control diets , respectively ; the difference was significant ( P < 0.05 ) . The rate of change over time was also significantly greater after the high-protein diet than after the control diet ( P < 0.001 ) . Fasting triacylglycerol was significantly lower after the high-protein diet than after the control diet . Insulin , C-peptide , and free fatty acid concentrations were not significantly different after the 2 diets . CONCLUSION A high-protein diet lowers blood glucose postpr and ially in persons with type 2 diabetes and improves overall glucose control . However , longer-term studies are necessary to determine the total magnitude of response , possible adverse effects , and the long-term acceptability of the diet
There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .