In addition , 19 letters to the editor/ review s/editorials/experts ' surveys/experts ' opinion were used for discussion purpose s. Conclusions NVAF is highly prevalent among ICH survivors .
The risks of IS , recurrent ICH , and mortality are heightened in this group .
Most published data show a net benefit in terms of IS prevention and mortality when anticoagulation is restarted .
Background We summarize the existing evidence on the potential benefit of oral anticoagulation ( OAC ) in intracerebral hemorrhage ( ICH ) survivors with nonvalvular atrial fibrillation ( NVAF ) .
Risk factors for impaired outcome after spontaneous intracerebral hemorrhage.
OBJECTIVE To search out independent prognostic factors , including preictal variables for outcome of spontaneous intracerebral hemorrhage . DESIGN Prospect i ve follow-up study . PATIENTS One hundred fifty-six consecutive patients ( 96 men and 60 women ) aged 16 to 60 years admitted as emergencies after bleeding . MAIN OUTCOME MEASURES Potential risk factors ( baseline characteristics , health habits , and clinical variables ) for death and impaired outcome were studied prospect ively up to 1 year after hemorrhage . RESULTS One year after hemorrhage , 64 patients ( 41 % ) were independent and 34 patients ( 22 % ) were dependent in the activities of daily living ; 58 patients ( 37 % ) had died . Risk of death was predicted , after adjustment for sex , age , hypertension , and body mass index , by clinical condition at admission according to the Glasgow Coma Scale ( P < .001 ) and the occurrence of subcortical hematoma ( odds ratio [ OR ] , 0.18 ; 95 % confidence interval [ CI ] , 0.04 to 0.91 ; P = .04 ) . Risk of poor outcome ( dependent state or death ) was predicted , after adjustment for sex , hypertension , body mass index , cigarette smoking , presence of intraventricular hemorrhage , and surgery , significantly by the Glasgow Coma Scale ( P < .001 ) ; presence of subcortical hematoma ( OR , 0.04 ; 95 % CI , 0.01 to 0.27 ; P < .001 ) ; volume of hematoma ( P = .03 ) ; age ( P = .004 ) ; amount of alcohol consumed within 1 week before hemorrhage ( P = .03 ) ; and presence of cerebellar hematoma ( OR , 0.13 ; 95 % CI , 0.02 to 0.95 ; P = .04 ) . Significant independent predictors of impaired outcome ( assessed with the Glasgow Outcome Scale ) were the Glasgow Coma Scale ( P < .001 ) ; presence of subcortical hematoma ( OR , 0.26 ; 95 % CI , 0.10 to 0.67 ; P = .006 ) ; alcohol intake within 1 week ( P = .002 ) ; and presence of cerebellar ( OR , 0.16 ; 95 % CI , 0.04 to 0.60 ; P = .008 ) , intraventricular ( OR , 2.74 ; 95 % CI , 1.19 to 6.28 ; P = .02 ) , or cau date hemorrhage ( OR , 0.13 ; 95 % CI , 0.02 to 0.77 ; P = .03 ) . The mean erythrocyte corpuscular volume was directly associated with an impaired outcome ( P < .05 ) . CONCLUSION In addition to severity and location of the hemorrhage , the age of the patient and the amount of alcohol consumed within 1 week seem to be independent determinants of outcome after intracerebral hemorrhage
In addition , 19 letters to the editor/ review s/editorials/experts ' surveys/experts ' opinion were used for discussion purpose s. Conclusions NVAF is highly prevalent among ICH survivors .
The risks of IS , recurrent ICH , and mortality are heightened in this group .
Most published data show a net benefit in terms of IS prevention and mortality when anticoagulation is restarted .
Background We summarize the existing evidence on the potential benefit of oral anticoagulation ( OAC ) in intracerebral hemorrhage ( ICH ) survivors with nonvalvular atrial fibrillation ( NVAF ) .