Conclusions The last 10 years has seen a substantial increase in the number of mapping studies and some evidence of advancement in methods with consideration of models beyond OLS and greater reporting of predictive ability of mapping functions
Background Mapping is an increasingly common method used to predict instrument-specific preference-based health-state utility values ( HSUVs ) from data obtained from another health-related quality of life ( HRQoL ) measure .
There have been several method ological developments in this area since a previous review up to 2007 .
Mapping analyses to estimate health utilities based on responses to the OM8-30 otitis media questionnaire
Purpose To investigate the statistical relationship between the OM8 - 30 health-related quality of life measure for children with otitis media with effusion ( OME ) and measures of health utility ( Health Utilities Index [ HUI ] Mark 3 and Mark 2 ) and to develop models to estimate HUI3 and HUI2 health utilities from OM8 - 30 scores . Methods A placebo-controlled , r and omised trial ( GNOME ) evaluating intranasal mometasone in 217 children with OME provided concurrent responses to OM8 - 30 and HUI at three time points . Ordinary least squares ( OLS ) , generalised linear models and two-step regression analyses were used to predict HUI3 and HUI2 utilities based on OM8 - 30 facet and domain scores . Results OLS models including all nine OM8 - 30 facets with or without predicted hearing level ( HL ) produced the best predictions of HUI3 utilities ( mean absolute error : 0.134 with HL and 0.132 without ; R2 : 0.63 with HL and 0.596 without ) . An OLS model predicting HUI3 utilities based on the two OM8 - 30 domain scores , reported hearing difficulties , predicted HL , age and sex also produced accurate predictions . Conclusion Regression equations predicting HUI3 and HUI2 utilities based on OM8 - 30 facet and domain scores have been developed . These provide an empirical basis for estimating quality -adjusted life years ( QALYs ) for interventions in children with OME
Conclusions The last 10 years has seen a substantial increase in the number of mapping studies and some evidence of advancement in methods with consideration of models beyond OLS and greater reporting of predictive ability of mapping functions
Background Mapping is an increasingly common method used to predict instrument-specific preference-based health-state utility values ( HSUVs ) from data obtained from another health-related quality of life ( HRQoL ) measure .
There have been several method ological developments in this area since a previous review up to 2007 .