No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .
Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects.
Prior studies of medium-chain triglyceride ( MCT ) suggest that MCT might be a useful tool for body fat mass management in obese nondiabetic humans . We now report a pilot study that tests if MCT is beneficial for moderately overweight subjects with type 2 diabetes mellitus . The study was conducted in a group of 40 free-living subjects in an urban area of China . The subjects were r and omized into 2 test groups , with one given MCT and the other corn oil as control for long-chain triglycerides ( LCTs ) . The test oil ( 18 g/d ) was administered as part of daily food intake for 90 days . All subjects completed the study with self-reported full compliance . Body weight , waist circumference ( WC ) , and serum sample s were analyzed on days 0 , 45 , and 90 . The MCT group showed an across-time reduction in body weight and WC , an increase in serum C-peptide concentration , a reduction in homeostasis model assessment of insulin resistance , and a decrease in serum cholesterol concentration ( P < .05 , repeated measures ) . No significant across-time difference for the above parameters was detected for the LCT group . These changes were associated with an involuntary reduction in energy intake in the MCT group ( P < .05 , repeated measures ) . A between-group comparison also shows reduced body weight , WC , and homeostasis model assessment of insulin resistance in the MCT group compared with the LCT group at the end of the study . Collectively , our results suggest a link between moderate consumption of MCT and improved risk factors in moderately overweight humans in a low-cost , free-living setting
No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .