There was no significant change in the γGT levels .
Significant differences were not found .
CONCLUSION Silymarin minimally reduced , but without clinical relevance , the serum levels of ALT and AST .
AIM To evaluate the effect of silymarin on the serum levels of alanine aminotransferase ( ALT ) , aspartate aminotransferase ( AST ) and gamma glutamyl transpeptidase ( γGT ) in patients with liver diseases .
Effects of Mediterranean diet supplemented with silybin–vitamin E–phospholipid complex in overweight patients with non-alcoholic fatty liver disease
Background : Non-alcoholic fatty liver disease is the most common liver disease worldwide . Aim : The aim of this study is to compare the metabolic effects of the Mediterranean diet versus the diet associated with silybin , phosphatidylcholine and vitamin E complex in overweight patients with non-alcoholic fatty liver disease . Methods : Thirty Caucasian overweight patients were r and omized into three groups of 10 ( Groups A , B and C ) . A personalized Mediterranean diet was started in Group A and B patients . In association with the diet , Group B patients were given Realsil complex , daily , for 6 months . Group C patients refused any treatment . Results : We showed that the Mediterranean diet alone , or in association with the Realsil complex , led to the significant variation in BMI , waist circumference , total cholesterol and triglycerides . We also observed a statistically significant decrease in homeostasis model assessment technique in Group B patients
There was no significant change in the γGT levels .
Significant differences were not found .
CONCLUSION Silymarin minimally reduced , but without clinical relevance , the serum levels of ALT and AST .
AIM To evaluate the effect of silymarin on the serum levels of alanine aminotransferase ( ALT ) , aspartate aminotransferase ( AST ) and gamma glutamyl transpeptidase ( γGT ) in patients with liver diseases .