No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .
Effect of 3 modified fats and a conventional fat on appetite, energy intake, energy expenditure, and substrate oxidation in healthy men.
BACKGROUND Different dietary fats are metabolized differently in humans and may influence energy expenditure , substrate oxidation , appetite regulation , and body weight regulation . OBJECTIVE We examined the short-term effects of 4 triacylglycerols ( test fats ) on subjective appetite , ad libitum energy intake , meal-induced thermogenesis , and postpr and ial substrate oxidation . DESIGN Eleven healthy , normal-weight men ( mean age : 25.1 + /- 0.5 y ) consumed 4 different test fats [ conventional fat ( rapeseed oil ) and 3 modified fats ( lipase-structured fat , chemically structured fat , and physically mixed fat ) ] in a r and omized , double-blind , crossover design . RESULTS No significant differences in appetite sensations or ad libitum energy intakes were observed between the 4 test fats . Overall , the 4 fats exerted different effects on energy expenditure ( meal effect : P < 0.01 ) and substrate oxidation ( interaction between meal and time : P < 0.05 ) . In post hoc tests , the 3 modified fats result ed in significantly higher postpr and ial energy expenditure and fat oxidation than did the conventional fat ( P < 0.008 , Bonferroni adjusted ) ; no significant differences were observed between the 3 modified fats . CONCLUSIONS Structured fats do not change short-term postpr and ial appetite sensations or ad libitum energy intakes but do result in higher postpr and ial energy expenditure and fat oxidation than do conventional fats and hence promote negative energy and fat balance . In humans , a physically mixed fat ( trioctanoate + rapeseed oil ) is metabolized as quickly as are structured fats . The position of medium-chain fatty acids on the glycerol backbone of triacylglycerols does not seem to affect energy expenditure or appetite
No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .