Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .
Effects of androgen on sexual behavior in hypogonadal men.
Despite the widespread use of and rogen in the treatment of hypogonadal men , its efficacy in restoring sexual behavior to hypogonadal patients has not been established in appropriately controlled behavioral studies . Accordingly , testosterone enanthate or vehicle was injected once every 4 weeks i m in a double blind experiment . The subjects were six adult males , aged 32 - 65 yr , two with gonadal failure and four with secondary hypogonadism . Two doses of testosterone ( 100 and 400 mg ) were administered for approximately 5 months , with the treatments varied at r and om within and among subjects . Details of sexual activity and experience were followed by the use of daily logs . Frequencies of erections , including nocturnal erections and coitus , showed significant dose-related responses to and rogen treatment which closely followed the fluctuations in the circulating testosterone level . As indicated by the Profile of Mood States test , behavioral responses did not appear to be mediated by changes in mood . We concluded that the stimulatory effects of testosterone on sexual activity are rapid , reliable , and not due to a placebo effect . To maintain plasma testosterone and adequate sexual function within normal levels , even high doses of testosterone enanthate should be given no less frequency than once every 3 weeks
Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .