It can be concluded that physical activity may be effective in reducing burn-out risk .
The few observational studies linking sedentary and dietary behavior with burn-out risk suggest that being more sedentary and eating less healthy are each associated with higher burn-out risk .
Although it is believed that physical activity , sedentary , and dietary behavior ( i.e. , energy balance-related behavior ) may decrease the risk of burn-out  , the association between both is currently not well understood .
Therefore , the aim of this systematic review was to synthesize studies investigating the relationship between energy balance-related behavior  and  burn-out risk .
The Psychobiology of Burnout: Are There Two Different Syndromes?
Background : Plasma prolactin levels are sensitive to dopamine and serotonin function , and fatigue . Low cortisol , dopamine and /or serotonin may be involved in burnout and detachment . Methods : In this double-blind within-subject study , we treated 9 female burnout subjects and 9 controls with 35 mg cortisol and placebo orally . We measured state affect and plasma prolactin , oxytocin , cortisol and adrenocorticotropic hormone levels , and administered an attachment question naire . Results : The burnout subjects displayed an extreme distribution of basal prolactin levels , displaying higher or lower levels compared to the controls . The low prolactin burnouts had profoundly low attachment scores and tended to have low oxytocin levels . The high prolactin burnout subjects tended to show cortisol-induced decreased prolactin and fatigue , and increased vigor . Conclusion : Results are consistent with the hypothesis that burnout subjects are either characterized by low serotonergic function or by low dopaminergic function , and that the latter group benefits from cortisol replacement . These preliminary results suggest that differentiating between two syndromes may resolve inconsistencies in research on burnout , and be necessary for selecting the right treatment strategy
It can be concluded that physical activity may be effective in reducing burn-out risk .
The few observational studies linking sedentary and dietary behavior with burn-out risk suggest that being more sedentary and eating less healthy are each associated with higher burn-out risk .
Although it is believed that physical activity , sedentary , and dietary behavior ( i.e. , energy balance-related behavior ) may decrease the risk of burn-out  , the association between both is currently not well understood .
Therefore , the aim of this systematic review was to synthesize studies investigating the relationship between energy balance-related behavior  and  burn-out risk .