Results showed no significant effects on core symptomatology .
In conclusion , up to date , evidence regarding the potential utility of IN-OT in treating anxiety and depression is still inconclusive .
Several studies have demonstrated the neuromodulating function of oxytocin ( OT ) in response to anxiogenic stimuli as well as its potential role in the pathogenesis of depression .
Consequently , intranasal OT ( IN-OT ) has been proposed as a potential treatment of  anxiety and depressive disorders .
The present systematic review aim ed to summarize the r and omized controlled trials ( RCTs ) evaluating the effect of IN-OT on anxiety and depressive symptoms .
Cyberostracism: effects of being ignored over the Internet.
Ostracism is such a widely used and powerful tactic that the authors tested whether people would be affected by it even under remote and artificial circumstances . In Study 1 , 1,486 participants from 62 countries accessed the authors ' on-line experiment on the Internet . They were asked to use  mental visualization while playing a virtual tossing game with two others ( who were actually computer generated and controlled ) . Despite the minimal nature of their experience , the more participants were ostracized , the more they reported feeling bad , having less control , and losing a sense of belonging . In Study 2 , ostracized participants were more likely to conform on a subsequent task . The results are discussed in terms of supporting K. D. Williams 's ( 1997 ) need threat theory of ostracism
Results showed no significant effects on core symptomatology .
In conclusion , up to date , evidence regarding the potential utility of IN-OT in treating anxiety and depression is still inconclusive .
Several studies have demonstrated the neuromodulating function of oxytocin ( OT ) in response to anxiogenic stimuli as well as its potential role in the pathogenesis of depression .
Consequently , intranasal OT ( IN-OT ) has been proposed as a potential treatment of  anxiety and depressive disorders .
The present systematic review aim ed to summarize the r and omized controlled trials ( RCTs ) evaluating the effect of IN-OT on anxiety and depressive symptoms .