It can be concluded that physical activity may be effective in reducing burn-out risk .
The few observational studies linking sedentary and dietary behavior with burn-out risk suggest that being more sedentary and eating less healthy are each associated with higher burn-out risk .
Although it is believed that physical activity , sedentary , and dietary behavior ( i.e. , energy balance-related behavior ) may decrease the risk of burn-out  , the association between both is currently not well understood .
Therefore , the aim of this systematic review was to synthesize studies investigating the relationship between energy balance-related behavior  and  burn-out risk .
Is Objectively Assessed Sedentary Behavior, Physical Activity and Cardiorespiratory Fitness Linked to Brain Plasticity Outcomes in Old Age?
The aim of this cross-sectional study was to determine the associations of objective ly assessed habitual physical activity and physical performance with brain plasticity outcomes and brain-derived neurotrophic factor ( BDNF ) levels in cognitively healthy older adults . Physical performance was analyzed based on cardiopulmonary exercise-testing data and accelerometer-based physical activity was analyzed as total activity counts , sedentary time , light physical activity and moderate to vigorous physical activity . Brain plasticity outcomes included magnetic resonance spectroscopy (MRS)-based markers , quantitative imaging-based hippocampal volume and BDNF serum levels . The association between physical performance and hippocampal volume was strongly influenced by participants ' education , sex , age and BMI . Confounder-controlled correlation revealed significant associations of brain plasticity outcomes with physical activity but not with performance . MRS-based adenosine triphosphate to phosphocreatine and glycerophosphocholine to phosphocreatine ratios were significantly associated with accelerometer total activity counts . BDNF was detrimentally associated with sedentary time but beneficially related to  accelerometer total activity  counts and moderate to vigorous physical activity . Exceeding the current moderate to vigorous physical activity recommendations led to significantly higher BDNF levels . Our results indicate that regular physical activity might be beneficial for preserving brain plasticity in higher age . In this study these associations were not mediated significantly by physical performance . Overall physical activity and exceeding current moderate to vigorous physical activity recommendations were positively associated with BDNF . Sedentary behavior , however , seems to be negatively related to neurotrophic factor bioavailability in the elderly
It can be concluded that physical activity may be effective in reducing burn-out risk .
The few observational studies linking sedentary and dietary behavior with burn-out risk suggest that being more sedentary and eating less healthy are each associated with higher burn-out risk .
Although it is believed that physical activity , sedentary , and dietary behavior ( i.e. , energy balance-related behavior ) may decrease the risk of burn-out  , the association between both is currently not well understood .
Therefore , the aim of this systematic review was to synthesize studies investigating the relationship between energy balance-related behavior  and  burn-out risk .