AUTHORS ' CONCLUSIONS Feeding with a soy formula can not be recommended for prevention of allergy or food intolerance in infants at high risk of allergy or food intolerance .
BACKGROUND Allergies and food reactions in infants and children are common and may be associated with a variety of foods including adapted cow 's milk formula .
Soy based formulas have been used to treat infants with allergy or food intolerance .
However , it is unclear whether they can help prevent allergy and food intolerance in infants without clinical evidence of allergy or food intolerance .
OBJECTIVES To determine the effect of feeding adapted soy formula compared to human milk , cow 's milk formula or a hydrolysed protein formula on preventing allergy or food intolerance in infants without clinical evidence of allergy or food intolerance .
Reduced bone mineralization in infants fed palm olein-containing formula: a randomized, double-blinded, prospective trial.
OBJECTIVE Palm and palm olein ( PO ) oils are used in some infant formula fat blends to match the fatty acid profile of human milk , but their presence has been shown to lower calcium and fat absorption . We aim ed to determine if the reported differences in calcium absorption could affect skeletal development by comparing bone mineral accretion in healthy term infants fed a milk-based formula with ( PMF ) or without PO . METHODS Whole body bone mineralization was evaluated in healthy term infants fed 1 of 2 coded , commercially available , ready-to-feed infant formulas in a r and omized , double-blind , parallel study . Subjects were fed either 1 ) . PMF formula ( Enfamil with iron ; Mead Johnson Division of Bristol Myers , Evansville , IN ; N = 63 ) containing PO/coconut/soy/high-oleic sunflower oils ( 45/20/20/15 % oil ) ; or 2 ) . milk-based formula without PO ( Similac with iron ; Ross Products Division Abbott Laboratories , Columbus , OH ; N = 65 ) , containing high-oleic safflower/coconut/soy oils ( 40/30/30 % oil ) from enrollment by 2 weeks after birth until 6 months . Anthropometrics and formula intake were determined monthly ; total body bone mineral content ( BMC ) and bone mineral density ( BMD ) were measured at baseline , 3 , and 6 months of age using dual energy x-ray absorptiometry . RESULTS Intent-to-treat analyses indicated no significant differences between feeding groups in weight , length , head circumference , or formula intake throughout the study . BMC and BMD were not different at baseline but repeated measures analyses show that infants fed PMF had significantly lower BMC and BMD at 3 and 6 months . CONCLUSIONS Healthy term infants fed a formula containing PO as the predominant oil in the fat blend had significantly lower BMC and BMD than those fed a formula without PO . The inclusion of PO in infant formula at levels needed to provide a fatty acid profile similar to that of human milk leads to lower bone mineralization
AUTHORS ' CONCLUSIONS Feeding with a soy formula can not be recommended for prevention of allergy or food intolerance in infants at high risk of allergy or food intolerance .
BACKGROUND Allergies and food reactions in infants and children are common and may be associated with a variety of foods including adapted cow 's milk formula .
Soy based formulas have been used to treat infants with allergy or food intolerance .
However , it is unclear whether they can help prevent allergy and food intolerance in infants without clinical evidence of allergy or food intolerance .
OBJECTIVES To determine the effect of feeding adapted soy formula compared to human milk , cow 's milk formula or a hydrolysed protein formula on preventing allergy or food intolerance in infants without clinical evidence of allergy or food intolerance .