Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .
What predicts and what mediates the response of urge urinary incontinence to biofeedback?
AIMS To better target a behavioral approach for  urge urinary incontinence ( UUI )  and enhance its efficacy by ( 1 ) identifying predictors of response to biofeedback-assisted pelvic muscle training ( BFB ) , and ( 2 ) determining factors that mediate response . METHODS BFB ( four biweekly visits ) was administered to 183 women > 60 years ( mean = 73.6 ) . Before and after intervention , all underwent comprehensive evaluation and videourodynamic testing . Postulated predictors and mediators from four urodynamic domains , specified a priori , were correlated with reduction in UUI frequency . RESULTS Median UUI frequency decreased from 3.2/day to 1/day ( P = 0.0001 ) . UUI improved by ≥50 % in 55 % of subjects and by 100 % in 13 % of subjects . Frequent UUI predicted poor response ( P < 0.01 ) . Of the urodynamic parameters , only high amplitude and briskness of detrusor overactivity ( DO ) predicted decreased response ( P < 0.05 and P < 0.01 ) and these could be measured only in the 43 % of subjects with elicitable DO . Decreased DO elicitability was the only urodynamic variable that changed in concert with improvement and thus was a c and i date mediator . Response was neither predicted nor mediated by proprioception/warning , cystometric capacity , detrusor contractility , sphincter strength , or baseline DO elicitability . CONCLUSIONS Severe DO predicts poor response to BFB . Good response is mediated by reduction in DO elicitability . Other than baseline UUI frequency , there are no other clinical ly or urodynamically important predictors or mediators of BFB response in this population . BFB may be best for patients with less severe DO . Future research to enhance its efficacy might better focus on the brain than on the lower urinary tract
Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .