None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .
[Effects of intensive insulin therapy on insulin resistance and serum proteins after radical gastrectomy].
OBJECTIVE To investigate the effects of intensive insulin therapy on insulin resistance(IR ) and serum proteins  after radical gastrectomy . METHODS Twenty-two gastric cancer patients were r and omly divided into the control ( n=11 ) and intensive insulin therapy group ( n=11 ) , and underwent  distal radical subtotal gastrectomy under epidural anesthesia .  Fasting blood glucose ( FBG ) , fasting insulin ( FINS ) and serum proteins were assayed preoperatively and at day 1 , 3 , 7 postoperatively . Insulin resistance index was calculated using homeostasis model assessment ( HOMA ) . The length of hospital stay and postoperative complications were recorded respectively . RESULTS (1)The levels of FBG , FINS , lnHOMA-IR ( P<0.01,P<0.05 ) and the incidence of insulin resistance were remarkably decreased by intensive insulin therapy after the surgical procedure.(2)The levels of serum transferrin ( TRF ) , prealbumin ( PRE ) and retinal binding protein ( RBP ) in the intensive insulin therapy group were significantly improved as compared to control group after operation(P<0.05 ) . ( 3 ) The duration of fever , antibiotic use , passage of gas by anus , length of hospital stay and the occurrence of postoperative complications were also significantly lower than those in control group(P<0.01,P<0.05 ) . CONCLUSION Compared to routine therapy , the intensive insulin therapy has more beneficial effects on the patients undergone distal radical subtotal gastrectomy in decreasing the insulin resistance , improving the status of nutrition and preventing postoperative complications
None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .