Home-based prescribed exercise improves balance-related activities and gait speed in people with Parkinson 's disease , and these improvements are similar to improvements with equivalent centre-based exercise .
QUESTIONS In people with Parkinson 's disease , does home-based prescribed exercise improve balance-related activities and quality of life compared with no intervention ?
Are the effects of home-based exercise similar to those of equivalent centre-based exercise ?
Early predictors of mortality in parkinsonism and Parkinson disease
Objective To examine mortality and associated risk factors , including possible effects of mild cognitive impairment , imaging , and CSF abnormalities , in a community-based population with incident parkinsonism and Parkinson disease . Methods One hundred eighty-two patients with new-onset , idiopathic parkinsonism were diagnosed from January 2004 through April 2009 , in a catchment area of 142,000 inhabitants in Sweden . Patients were comprehensively investigated according to a multimodal research protocol and followed prospect ively for up to 13.5 years . A total of 109 patients died . Mortality rates in the general Swedish population were used to calculate st and ardized mortality ratio and expected survival , and Cox proportional hazard models were used to investigate independent predictors of mortality . Results The st and ardized mortality ratio for all patients was 1.84 ( 95 % confidence interval 1.50–2.22 , p < 0.001 ) . Patients with atypical parkinsonism ( multiple system atrophy or progressive supranuclear palsy ) had the highest mortality . In early Parkinson disease , a mild cognitive impairment diagnosis , freezing of gait , hyposmia , reduced dopamine transporter activity in the cau date , and elevated leukocytes in the CSF were significantly associated with shorter survival . Conclusion Although patients presenting with idiopathic parkinsonism have reduced survival , the survival is highly dependent on the type and characteristics of the parkinsonian disorder . Patients with Parkinson disease presenting with normal cognitive function seem to have a largely normal life expectancy . The finding of a subtle CSF leukocytosis in patients with Parkinson disease with short survival may have clinical implication
Home-based prescribed exercise improves balance-related activities and gait speed in people with Parkinson 's disease , and these improvements are similar to improvements with equivalent centre-based exercise .
QUESTIONS In people with Parkinson 's disease , does home-based prescribed exercise improve balance-related activities and quality of life compared with no intervention ?
Are the effects of home-based exercise similar to those of equivalent centre-based exercise ?