Conclusion This meta- analysis suggests that probiotic and synbiotic supplementation may be beneficial in  lowering FBG in adults with high baseline FBG ( ≥7 mmol/L ) and that multispecies probiotics may have more impact on FBG than single species
Purpose  High fasting blood glucose ( FBG ) can lead to chronic diseases such as diabetes mellitus , cardiovascular and kidney diseases .
Consuming probiotics or synbiotics may improve FBG .
A systematic review and meta- analysis of controlled trials was conducted to clarify the effect of probiotic and synbiotic consumption on FBG levels .
Evaluation of safety and tolerance of microencapsulated Lactobacillus reuteri NCIMB 30242 in a yogurt formulation: a randomized, placebo-controlled, double-blind study.
Probiotic organisms have shown promise in treating diseases . Previously , we have reported on the efficacy of microencapsulated Lactobacillus reuteri NCIMB 30242 in a yogurt formulation at lowering serum cholesterol levels in otherwise healthy hypercholesterolemic adults . This study investigates the safety and toxicology of oral ingestion of microencapsulated L. reuteri NCIMB 30242 in a yogurt formulation . A r and omized group of 120 subjects received a dose of 5 × 10(10 ) CFU microencapsulated L. reuteri NCIMB 30242 in yogurt ( n=59 ) or placebo yogurt ( n=61 ) twice/day for 6 weeks . Clinical chemistry and hematological parameters of safety were analyzed . Fecal sample s were collected at these time points for the analysis of deconjugated bile acids . The frequency , duration and intensity of adverse events ( AEs ) and clinical significance of safety parameters were recorded for both groups . No clinical ly significant differences between the probiotic yogurt and placebo yogurt treated groups were detected in either the blood clinical chemistry or hematology results and there was no significant increase in fecal deconjugated bile acids ( P>0.05 ) between treated and control groups . The frequency and intensity of AEs was similar in the two groups . These results demonstrate the safe use of this formulation in food
Conclusion This meta- analysis suggests that probiotic and synbiotic supplementation may be beneficial in  lowering FBG in adults with high baseline FBG ( ≥7 mmol/L ) and that multispecies probiotics may have more impact on FBG than single species
Purpose  High fasting blood glucose ( FBG ) can lead to chronic diseases such as diabetes mellitus , cardiovascular and kidney diseases .
Consuming probiotics or synbiotics may improve FBG .
A systematic review and meta- analysis of controlled trials was conducted to clarify the effect of probiotic and synbiotic consumption on FBG levels .