We conclude based on high quality evidence from r and omized controlled trials ( RCT ) , systematic review s and meta-analyses of cohort studies that singling out added sugars as unique culprits for metabolically based diseases such as obesity , diabetes and cardiovascular disease appears inconsistent with modern , high quality evidence and is very unlikely to yield health benefits .
While it is prudent to consume added sugars in moderation , the reduction of these components of the diet without other reductions of caloric sources seems unlikely to achieve any meaningful benefit
Added sugars are a controversial and hotly debated topic .
Consumption of added sugars has been implicated in increased risk of a variety of chronic diseases including obesity , cardiovascular disease , diabetes and non-alcoholic fatty liver disease ( NAFLD ) as well as cognitive decline and even some cancers .
Support for these putative associations has been challenged , however , on a variety of fronts .
The purpose of the current review is to summarize high impact evidence including systematic review s , meta-analyses , and r and omized controlled trials ( RCTs ) , in an attempt to provide an overview of current evidence related to added sugars and health considerations .
This paper is an extension of a symposium held at the Experimental Biology 2015 conference entitled " Sweeteners and Health : Current Underst and ings , Controversies , Recent Research Findings and Directions for Future Research " .
Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis.
BACKGROUND Although dietary recommendations have focused on restricting saturated fat ( SF ) consumption to reduce cardiovascular disease ( CVD ) risk , evidence from prospect i ve studies has not supported a strong link between total SF intake and CVD events . An underst and ing of whether food sources of SF influence these relations may provide new insights . OBJECTIVE We investigated the association of SF consumption from different food sources and the incidence of CVD events in a multiethnic population . DESIGN Participants who were 45 - 84 y old at baseline ( n = 5209 ) were followed from 2000 to 2010 . Diet was assessed by using a 120-item food-frequency question naire .  CVD incidence ( 316 cases ) was assessed during follow-up visits . RESULTS After adjustment for demographics , lifestyle , and dietary confounders , a higher intake of dairy SF was associated with lower CVD risk [ HR ( 95 % CI ) for + 5 g/d and + 5 % of energy from dairy SF : 0.79 ( 0.68 , 0.92 ) and 0.62 ( 0.47 , 0.82 ) , respectively ] . In contrast , a higher intake of meat SF was associated with greater CVD risk [ HR ( 95 % CI ) for + 5 g/d and a + 5 % of energy from meat SF : 1.26 ( 1.02 , 1.54 ) and 1.48 ( 0.98 , 2.23 ) , respectively ] . The substitution of 2 % of energy from meat SF with energy from dairy SF was associated with a 25 % lower CVD risk [ HR ( 95 % CI ) : 0.75 ( 0.63 , 0.91 ) ] . No associations were observed between plant or butter SF and CVD risk , but ranges of intakes were narrow . CONCLUSION Associations of SF with health may depend on food-specific fatty acids or other nutrient constituents in foods that contain SF , in addition to SF
We conclude based on high quality evidence from r and omized controlled trials ( RCT ) , systematic review s and meta-analyses of cohort studies that singling out added sugars as unique culprits for metabolically based diseases such as obesity , diabetes and cardiovascular disease appears inconsistent with modern , high quality evidence and is very unlikely to yield health benefits .
While it is prudent to consume added sugars in moderation , the reduction of these components of the diet without other reductions of caloric sources seems unlikely to achieve any meaningful benefit
Added sugars are a controversial and hotly debated topic .
Consumption of added sugars has been implicated in increased risk of a variety of chronic diseases including obesity , cardiovascular disease , diabetes and non-alcoholic fatty liver disease ( NAFLD ) as well as cognitive decline and even some cancers .
Support for these putative associations has been challenged , however , on a variety of fronts .
The purpose of the current review is to summarize high impact evidence including systematic review s , meta-analyses , and r and omized controlled trials ( RCTs ) , in an attempt to provide an overview of current evidence related to added sugars and health considerations .
This paper is an extension of a symposium held at the Experimental Biology 2015 conference entitled " Sweeteners and Health : Current Underst and ings , Controversies , Recent Research Findings and Directions for Future Research " .