Rehabilitation programs that promote physiotherapy techniques such as exercise , mobilization , and body awareness ( e.g. , MRT and GET ) are the most effective in reducing medium and long-term fatigue severity in CFS patients
OBJECTIVE The objectives of this work were to fill the gap in the scientific literature and to evaluate the results of physical therapy treatments  in individuals affected by chronic fatigue syndrome , considering only studies that employed a r and omized controlled trial .
Multidisciplinary rehabilitation treatment versus cognitive behavioural therapy for patients with chronic fatigue syndrome: a randomized controlled trial.
OBJECTIVES The aim of this trial was to evaluate the difference in treatment effect , at 26 and 52 weeks after the start of treatment , between cognitive behavioural therapy ( CBT ) and multidisciplinary rehabilitation treatment ( MRT ) for patients with chronic fatigue syndrome ( CFS ) . DESIGN Multicentre , r and omized controlled trial of patients with CFS . Participants were r and omly assigned to MRT or CBT . SETTING Four rehabilitation centres in the Netherl and s. SUBJECTS A total of 122 patients participated in the trial . MAIN OUTCOME MEASURES Primary outcomes were fatigue measured by the fatigue subscale of the Checklist Individual Strength and health-related quality of life measured by the Short-Form 36 . Outcomes were assessed prior to treatment and at 26 and 52 weeks after treatment initiation . RESULTS A total of 114 participants completed the assessment at 26 weeks , and 112 completed the assessment at 52 weeks . MRT was significantly more effective than CBT in reducing fatigue at 52 weeks . The estimated difference in fatigue between the two treatments was -3.02 [ 95 % confidence interval ( CI ) -8.07 to 2.03 ; P = 0.24 ] at 26 weeks and -5.69 ( 95 % CI -10.62 to -0.76 ; P = 0.02 ) at 52 weeks . Patients showed an improvement in quality of life over time , but between-group differences were not significant . CONCLUSION This study provides evidence that MRT is more effective in reducing long-term fatigue severity than CBT in patients with CFS . Although implementation in comparable population s can be recommended based on clinical effectiveness , it is advisable to analyse the cost-effectiveness and replicate these findings in another multicentre trial
Rehabilitation programs that promote physiotherapy techniques such as exercise , mobilization , and body awareness ( e.g. , MRT and GET ) are the most effective in reducing medium and long-term fatigue severity in CFS patients
OBJECTIVE The objectives of this work were to fill the gap in the scientific literature and to evaluate the results of physical therapy treatments  in individuals affected by chronic fatigue syndrome , considering only studies that employed a r and omized controlled trial .