A greater reduction in BMI was found with multiple species of probiotics .
Consuming probiotics  could reduce body weight and BMI , with a potentially greater effect when multiple species of probiotics were consumed , the duration of intervention was ≥8 weeks , or the objects were overweight
OBJECTIVE To assess the efficacy of probiotic therapies on body weight and BMI  using a meta- analysis of r and omized , controlled trials .
Evaluation of safety and tolerance of microencapsulated Lactobacillus reuteri NCIMB 30242 in a yogurt formulation: a randomized, placebo-controlled, double-blind study.
Probiotic organisms have shown promise in treating diseases . Previously , we have reported on the efficacy of microencapsulated Lactobacillus reuteri NCIMB 30242 in a yogurt formulation at lowering serum cholesterol levels in otherwise healthy hypercholesterolemic adults . This study investigates the safety and toxicology of oral ingestion of microencapsulated L. reuteri NCIMB 30242 in a yogurt formulation . A r and omized group of 120 subjects received a dose of 5 × 10(10 ) CFU microencapsulated L. reuteri NCIMB 30242 in yogurt ( n=59 ) or placebo yogurt ( n=61 ) twice/day for 6 weeks . Clinical chemistry and hematological parameters of safety were analyzed . Fecal sample s were collected at these time points for the analysis of deconjugated bile acids . The frequency , duration and intensity of adverse events ( AEs ) and clinical significance of safety parameters were recorded for both groups . No clinical ly significant differences between the probiotic yogurt and placebo yogurt treated groups were detected in either the blood clinical chemistry or hematology results and there was no significant increase in fecal deconjugated bile acids ( P>0.05 ) between treated and control groups . The frequency and intensity of AEs was similar in the two groups . These results demonstrate the safe use of this formulation in food
A greater reduction in BMI was found with multiple species of probiotics .
Consuming probiotics  could reduce body weight and BMI , with a potentially greater effect when multiple species of probiotics were consumed , the duration of intervention was ≥8 weeks , or the objects were overweight
OBJECTIVE To assess the efficacy of probiotic therapies on body weight and BMI  using a meta- analysis of r and omized , controlled trials .