Therefore , vitamin A supplementation alone may reduce the risk of anemia , by improving hemoglobin and ferritin levels in individuals with low serum retinol levels
ABSTRACT Anemia is a worldwide public health problem that can be related to many causes , including vitamin A deficiency .
The aim of this study was to assess and estimate the effect of vitamin A supplementation ( VAS ) on iron status biomarkers and anemia in humans .
Effect of biscuits fortified with different doses of vitamin A on indices of vitamin A status, haemoglobin and physical growth levels of pre-school children in Chongqing.
OBJECTIVE To investigate the efficacy of biscuits fortified with different doses of vitamin A on improving vitamin A deficiency ( VAD ) , anaemia and physical growth of pre-school children .  DESIGN A r and omised double-masked population -based field interventional trial with a positive control group . SETTING Banan district of Chongqing , China . SUBJECTS A total of 580 pre-school children aged 3 - 6 years were r and omly recruited into four groups . Children in groups I and II were given biscuits fortified with vitamin A at 30 % of the recommended daily intake ( RDA ) and 100 % of the RDA once a day for 9 and 3 months , respectively . Children in group III received biscuits containing 20,000 IU of vitamin A once a week for 3 months . Initially , the children in group IV received a 200,000 IU vitamin A capsule just once . At the beginning and end of the study , blood sample s were collected to measure Hb , serum retinol , retinol-binding protein and prealbumin , and weight and height were measured . RESULTS All the fortification types significantly decreased the prevalence of VAD and anaemia in each group ( P < 0.05 ) . The effect of 9-month intervention on group I was the most efficient ( P < 0.0045 ) . After intervention , the Z-scores of height-for-age , weight-for-age and weight-for-height in all groups increased markedly compared with baseline ( P < 0.05 ) , but no significant difference was observed among the groups . CONCLUSIONS Data indicated that consuming vitamin A-fortified biscuits with daily 100 % RDA for 3 months has the same effect on the improvement of VAD , anaemia and physical growth as did the weekly 20,000 IU and single 200,000 IU administration in pre-school children
Therefore , vitamin A supplementation alone may reduce the risk of anemia , by improving hemoglobin and ferritin levels in individuals with low serum retinol levels
ABSTRACT Anemia is a worldwide public health problem that can be related to many causes , including vitamin A deficiency .
The aim of this study was to assess and estimate the effect of vitamin A supplementation ( VAS ) on iron status biomarkers and anemia in humans .