We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .
Maxepa versus bezafibrate in hyperlipidemic cardiac transplant recipients.
Accelerated coronary artery disease is the most serious obstacle to long-term survival in cardiac transplant recipients . Lipid abnormalities are found frequently in these patients , and there is growing evidence that even minimally increased levels of cholesterol and triglycerides contribute to the development of accelerated coronary artery disease . However , the optimal lipid-lowering therapy after cardiac transplantation has not been defined . In an open , r and omized study , the efficacy and safety of bezafibrate ( 400 mg/day ) and fish oil ( Maxepa ) ( 10 g/day ) for 3 months were compared in 87 cardiac transplant recipients with serum total cholesterol > 6.5 or triglycerides > 2.8 mmol/liter , or both . After 1 month , bezafibrate reduced total cholesterol by 13 % , low-density lipoprotein cholesterol by 20 % and apolipoprotein B by 13 % . It also increased apolipoprotein A1 and high-density lipoprotein cholesterol by 12 and 20 % , respectively , and significantly reduced fibrinogen at 3 months . Maxepa had no significant effect on these variables , but was as effective as bezafibrate in reducing triglycerides ( 36 and 31 % , respectively ) . Both drugs increased lipoprotein ( a ) to a similar extent , and bezafibrate significantly increased serum creatinine . These results suggest that bezafibrate has better lipid- , apolipoprotein- and hemostatic modifying properties than does Maxepa , but its potentially adverse effect on renal function needs further investigation
We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .