Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Laparoscopic Cholecystectomy Without Prophylactic Antibiotics: A Prospective Study
Laparoscopic cholecystectomy has become the new gold st and ard for management of symptomatic gallstones .  Prophylactic antibiotics are used in elective surgery by the majority of surgeons , and their role in biliary tract surgery has been well established for a sub population of high-risk patients . This consensus has been derived from multiple studies involving biliary tract surgery before and in the era of laparoscopic cholecystectomy . But the use of prophylactic antibiotics in laparoscopic cholecystectomy especially in the low-risk group is now controversial and varied among the surgeons all over the world . To study the role of prophylactic antibiotics in laparoscopic cholecystectomy in different risk groups of patients , a prospect i ve study was conducted in the Department of Surgery of Bankura Sammilani Medical College and Hospital from January 2010 to July 2011 . All patients with symptomatic gallstones who underwent elective laparoscopic cholecystectomy during this period are included in this study . One hundred and two patients with symptomatic gallstones were operated on by laparoscopic technique  without receiving preoperative  antibiotics and studied over a period of 1.5 years . Ages ranged from 11 to 70 years ( mean age of 33 years ) . There were 14 males ( 13.72 % of the patients ) and 88 females ( 86.27 % of the patients ) . There was no wound infection ( class I ) in 99 patients , and class II type of wound infection , i.e. , surgical site infection , occurred in three patients ( i.e. , 2.94 % ) out of a total of 102 patients . Swabs were taken for culture and sensitivity ; Staphylococcus aureus was found in two patients and Streptococcus viridans in one patient . In all three patients , infection occurred at the umbilical port sites , detected on the 3rd and 4th postoperative days . Antibiotic prophylaxis is not necessary in low-risk patients with symptomatic gallstone disease undergoing elective laparoscopic cholecystectomy to prevent postoperative infection-related complications . Preoperative skin preparation with chlorhexidine gluconate scrub may replace the use of prophylactic antibiotics for prevention of infection-related complications in patients undergoing elective laparoscopic cholecystectomy
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .