The review found that multifaceted interventions , addressing several non-adherence factors , were comparatively more effective in improving medication adherence and glycaemic target in patients with T2D than single strategies .
However , interventions with similar components and those addressing similar non-adherence factors demonstrated mixed results , making it difficult to conclude on effective intervention strategies to promote adherence .
Educational strategies have remained the most popular intervention strategy , followed by behavioural , with affective components becoming more common in recent years .
There is a noticeable shift in the literature from using single to multifaceted intervention strategies addressing a range of factors impacting adherence to medications .
BACKGROUND Poor adherence to anti-diabetic medications contributes to suboptimal glycaemic control in patients with type 2 diabetes ( T2D ) .
A range of interventions have been developed to promote anti-diabetic medication adherence .
However , there has been very little focus on the characteristics of these interventions and how effectively they address factors that predict non-adherence .
In this systematic review we assessed the characteristics of interventions that aim ed to promote adherence to anti-diabetic medications .
The Pharmaceutical care of patients with type 2 diabetes mellitus
Objective To evaluate the efficiency of pharmaceutical care on the control of clinical parameters , such as fasting glycaemia and glycosylated haemoglobin in patients with Type 2 Diabetes mellitus . Setting This study was conducted at the Training and Community Health Centre of the College of Medicine of Ribeirao Preto , University of Sao Paulo , Brazil . Methods A prospect i ve and experimental study was conducted with 71 participants divided in two groups : ( i ) pharmaceutical care group ( n=40 ) , and ( ii ) the control group ( n=31 ) . The distribution of patients within these groups was made casually , and the patients were monitored for 12 months . Main outcome measure : Values for fasting glycaemia and glycosylated haemoglobin were collected . Results Mean values of fasting glycaemia in the pharmaceutical care group were significantly reduced whilst a small reduction was detected in the control group at the same time . A significant reduction in the levels of glycosylated haemoglobin was detected in patients in the pharmaceutical care group , and an average increase was observed in the control group . Furthermore , the follow-up of the intervention group by a pharmacist contributed to the resolution of 62.7 % of 142 drug therapy problems identified . Conclusion In Brazil , the information provided by a pharmacist to patients with Type 2 Diabetes mellitus increases compliance to treatment , solving or reducing the Drug Therapy Problem and , consequently , improving glycaemic control
The review found that multifaceted interventions , addressing several non-adherence factors , were comparatively more effective in improving medication adherence and glycaemic target in patients with T2D than single strategies .
However , interventions with similar components and those addressing similar non-adherence factors demonstrated mixed results , making it difficult to conclude on effective intervention strategies to promote adherence .
Educational strategies have remained the most popular intervention strategy , followed by behavioural , with affective components becoming more common in recent years .
There is a noticeable shift in the literature from using single to multifaceted intervention strategies addressing a range of factors impacting adherence to medications .
BACKGROUND Poor adherence to anti-diabetic medications contributes to suboptimal glycaemic control in patients with type 2 diabetes ( T2D ) .
A range of interventions have been developed to promote anti-diabetic medication adherence .
However , there has been very little focus on the characteristics of these interventions and how effectively they address factors that predict non-adherence .
In this systematic review we assessed the characteristics of interventions that aim ed to promote adherence to anti-diabetic medications .