Preoperative and post-operative intensive interventions improved symptoms of depression and anxiety , quality of life , diastolic blood pressure , and resting heart rate but not lipids or glycaemic measures .
This systematic review and meta- analysis of intervention studies aims to evaluate the effect of preoperative and /or post-operative support for adults who elect bariatric surgery delivered by a multidisciplinary team ( MDT )  on post-operative body composition , mental health , co-morbidities , quality of life , and side effects .
Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning, and Insulin Sensitivity After Gastric Bypass Surgery
Both Roux-en-Y gastric bypass ( RYGB ) surgery and exercise can improve insulin sensitivity in individuals with severe obesity . However , the impact of RYGB with or without exercise on skeletal muscle mitochondria , intramyocellular lipids , and insulin sensitivity index ( SI ) is unknown . We conducted a r and omized exercise trial in patients ( n = 101 ) who underwent RYGB surgery  and completed either a 6-month moderate exercise ( EX ) or a health education control ( CON ) intervention . SI was determined by intravenous glucose tolerance test . Mitochondrial respiration and intramyocellular triglyceride , sphingolipid , and diacylglycerol content were measured in vastus lateralis biopsy specimens . We found that EX provided additional improvements in SI and that only EX improved cardiorespiratory fitness , mitochondrial respiration and enzyme activities , and cardiolipin profile with no change in mitochondrial content . Muscle triglycerides were reduced in type I fibers in CON , and sphingolipids decreased in both groups , with EX showing a further reduction in a number of ceramide species . In conclusion , exercise superimposed on bariatric surgery – induced weight loss enhances mitochondrial respiration , induces cardiolipin remodeling , reduces specific sphingolipids , and provides additional improvements in insulin sensitivity
Preoperative and post-operative intensive interventions improved symptoms of depression and anxiety , quality of life , diastolic blood pressure , and resting heart rate but not lipids or glycaemic measures .
This systematic review and meta- analysis of intervention studies aims to evaluate the effect of preoperative and /or post-operative support for adults who elect bariatric surgery delivered by a multidisciplinary team ( MDT )  on post-operative body composition , mental health , co-morbidities , quality of life , and side effects .