In most respects , all membranes and enamel matrix derivative ( EMD ) delivered better outcomes , in the range of 1 to 2 mm , than open flap debridement .
The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level ( CAL ) gain than any open flap configuration .
GTR was confirmed to be superior to open flap debridement
In a 1998 review article , Laurell and colleagues performed a meta- analysis of relevant guided tissue regeneration ( GTR ) articles over the previous 20 years ( 1 ) .
The purpose of the present research was to exp and on that work , particularly search ing for trends discriminating between bioabsorbable and non-bioabsorbable barriers , as well as the use of enamel matrix derivative , with respect to interproximal bony defects .
Periodontal repair in intrabony defects treated with a calcium sulfate implant and calcium sulfate barrier.
THIS R AND OMIZED , CONTROLLED , CLINICAL STUDY was design ed to evaluate outcome following surgical implantation of an allogeneic , freeze-dried , demineralized bone matrix-calcium sulfate ( DBM+CS ) composite with a CS barrier in intrabony periodontal defects . Twenty-six patients contributing 26 deep intrabony defects completed the study . Thirteen patients received the DBM+CS implant . Thirteen patients received gingival flap surgery alone ( GFS ; control ) . Clinical outcome was assessed at 6 and 12 months postsurgery . At 12 months postsurgery , probing depth ( PD ) reduction ( mean + /-SD ) for the DBM+CS and GFS group was to 4.3+/-0.5 and 3.0+/-1.3 mm ; clinical attachment gain was to 2.9+/-0.8 and 1.7+/-1.5 mm ; and probing bone level gain was to 2.9+/-1.4 and 1.2+/-1.2 mm , respectively . There were no apparent differences between evaluations at 6 and 12 months postsurgery . Clinical improvements were significantly different from presurgery for both groups at both observation intervals ( P < 0.01 ) . There were no significant differences between groups in PD reduction and clinical attachment gain . Probing bone level gain was significantly greater in the DBM+CS group compared to controls ( P < 0.05 ) . In summary , surgical implantation of DBM+CS with a CS barrier result ed in reduced PD and improved attachment levels comparable to that achieved by gingival flap surgery alone . However , gain in probing bone levels in deep intrabony periodontal pockets assessed by clinical parameters was greater than that observed by gingival flap surgery alone . These changes were noted at both 6 and 12 months after surgery . This regenerative technique needs further biologic evaluation before being generally accepted
In most respects , all membranes and enamel matrix derivative ( EMD ) delivered better outcomes , in the range of 1 to 2 mm , than open flap debridement .
The use of any barrier type or EMD configuration was found to yield more Clinical Attachment Level ( CAL ) gain than any open flap configuration .
GTR was confirmed to be superior to open flap debridement
In a 1998 review article , Laurell and colleagues performed a meta- analysis of relevant guided tissue regeneration ( GTR ) articles over the previous 20 years ( 1 ) .
The purpose of the present research was to exp and on that work , particularly search ing for trends discriminating between bioabsorbable and non-bioabsorbable barriers , as well as the use of enamel matrix derivative , with respect to interproximal bony defects .