In healthy subjects , appetite and short term food intake , risk of cancer , risk of diabetes , risk of dental caries , weight gain and risk of obesity are the most investigated health outcomes .
Overall there is no conclusive evidence for beneficial and harmful effects on those outcomes .
In subjects with diabetes and hypertension , the evidence regarding health outcomes of NNS use is also inconsistent .
Background Food products containing non-nutritive sweeteners ( NNSs ) instead of sugar have become increasingly popular in the last decades .
Their appeal is obviously related to their calorie-free sweet taste .
However , with the dramatic increase in their consumption , it is reasonable and timely to evaluate their potential health benefits and , more importantly , potential adverse effects .
The main aim of this scoping review was to map the evidence about health outcomes possibly associated with regular NNS consumption by examining the extent , range , and nature of research activity in this area .
The effect of chewing sugar-free gum after meals on clinical caries incidence.
To determine the effect of chewing sugar-free gum on caries incidence , the authors conducted a r and omized clinical study . A total of 1,402 children in Puerto Rico , in grade s 5 through 7 at baseline , completed the study . They were r and omized by classroom into a control group or chewing gum group ; those in the gum group were instructed to chew sugar-free gum for 20 minutes after each of three meals a day . Clinical and radiographic evaluations were performed at baseline and after two and three years . The results show that all subjects and high-risk subjects , respectively , in the gum group developed 7.9 percent and 11.0 percent fewer decayed , missing or filled surfaces than subjects in the control group . Based on these findings , the authors concluded that chewing sorbitol-based sugar-free gum after eating significantly reduces the incidence of dental caries
In healthy subjects , appetite and short term food intake , risk of cancer , risk of diabetes , risk of dental caries , weight gain and risk of obesity are the most investigated health outcomes .
Overall there is no conclusive evidence for beneficial and harmful effects on those outcomes .
In subjects with diabetes and hypertension , the evidence regarding health outcomes of NNS use is also inconsistent .
Background Food products containing non-nutritive sweeteners ( NNSs ) instead of sugar have become increasingly popular in the last decades .
Their appeal is obviously related to their calorie-free sweet taste .
However , with the dramatic increase in their consumption , it is reasonable and timely to evaluate their potential health benefits and , more importantly , potential adverse effects .
The main aim of this scoping review was to map the evidence about health outcomes possibly associated with regular NNS consumption by examining the extent , range , and nature of research activity in this area .