ConclusionS -carboxymethylcysteine is effective in the treatment of children with glue ear .
Objective To establish the clinical relevance of S-carboxymethylcysteine in the treatment of glue ear in children using measures approximating those saving a child from operation for grommet insertion .
Management of middle-ear effusions in children.
A double-blind placebo controlled trial of Mucodyne ( carbocisteine , Berk Pharmaceuticals ) , Actifed ( triprolidine HC1 and pseudoephedrine HC1 , Wellcome ) and combined Mucodyne and Actifed in the treatment of middle-ear effusions is reported . The trial was undertaken to assess whether either preparation , alone or in combination , would reduce the number of children requiring surgical treatment for this condition . No statistical difference between the various groups in avoiding surgical treatment was detected . In those patients undergoing surgery , pre-operative treatment with Mucodyne was associated with a significantly greater number of ears restored to a normal appearance and middle ear function as measured by tympanometry . All patients relapsing after surgery belonged to the groups receiving placebo , Actifed or the combination of Mucodyne and Actifed prior to the operation
ConclusionS -carboxymethylcysteine is effective in the treatment of children with glue ear .
Objective To establish the clinical relevance of S-carboxymethylcysteine in the treatment of glue ear in children using measures approximating those saving a child from operation for grommet insertion .