Cemented and uncemented tibial components had different migration patterns .
For cemented tibial components there was no difference in migration between all-poly and metal-backed components , between mobile bearing and fixed bearing , between cruciate retaining and posterior stabilized .
Furthermore , no difference existed between TKR measured with model-based RSA or marker-based RSA methods .
For uncemented TKR there was some variation in migration with the highest migration for uncoated TKR .
Interpretation - The results from this meta- analysis on  RSA migration of TKR  are in line with both the survival analyses results from joint registries of these TKRs as well as revision rates results from meta-analyses , thus providing further proof for the association between early migration and late revision for loosening .
Purpose - We performed a systematic review and meta-analyses to evaluate the early and long-term migration patterns of  tibial components of TKR of all known RSA studies .
The beneficial effect of hydroxyapatite lasts
Background and purpose In contrast to early migration , the long-term migration of hydroxyapatite- ( HA- ) coated tibial components in TKA has been scantily reported . This r and omized controlled trial investigated the long-term migration measured by radiostereometric analysis ( RSA ) of HA-coated , uncoated , and cemented tibial components in TKA . Patients and methods 68 knees were r and omized to HA-coated ( n = 24 ) , uncoated ( n = 20 ) , and cemented ( n = 24 ) components .  All knees were prospect ively followed for 11–16 years , or until death or revision .  RSA  was used to evaluate migration at yearly intervals . Clinical and radiographic evaluation was according to the Knee Society system . A generalized linear mixed model ( GLMM , adjusted for age , sex , diagnosis , revisions , and BMI ) was used to take into account the repeated-measurement design . Results The present study involved 742 RSA analyses . The mean migration at 10 years was 1.66 mm for HA , 2.25 mm for uncoated and 0.79 mm for the cemented group ( p < 0.001 ) . The reduction of migration by HA as compared to uncoated components was most pronounced for subsidence and external rotation . 3 tibial components were revised for aseptic loosening ( 2 uncoated and 1 cemented ) , 3 for septic loosening ( 2 uncoated and 1 cemented ) , and 1 for instability ( HA-coated ) . 2 of these cases were revised for secondary loosening after a period of stability : 1 case of osteolysis and 1 case of late infection . There were no statistically significant differences between the fixation groups regarding clinical or radiographic scores .  Interpretation HA reduces migration of uncemented tibial components . This beneficial effect lasts for more than 10 years . Cemented components showed the lowest migration . Longitudinal follow-up of TKA with RSA allows early detection of secondary loosening
Cemented and uncemented tibial components had different migration patterns .
For cemented tibial components there was no difference in migration between all-poly and metal-backed components , between mobile bearing and fixed bearing , between cruciate retaining and posterior stabilized .
Furthermore , no difference existed between TKR measured with model-based RSA or marker-based RSA methods .
For uncemented TKR there was some variation in migration with the highest migration for uncoated TKR .
Interpretation - The results from this meta- analysis on  RSA migration of TKR  are in line with both the survival analyses results from joint registries of these TKRs as well as revision rates results from meta-analyses , thus providing further proof for the association between early migration and late revision for loosening .
Purpose - We performed a systematic review and meta-analyses to evaluate the early and long-term migration patterns of  tibial components of TKR of all known RSA studies .