Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .
Effect of garlic on blood lipids in patients with coronary heart disease.
The study was conducted on two groups of individuals . Group A consisted of 20 healthy volunteers who were fed garlic for 6 months and then followed for another 2 months without garlic . Garlic administration significantly lowered the serum cholesterol and triglycerides while raising the high-density lipoproteins .  Group B consisted of 62 patients with coronary heart disease with elevated serum cholesterol . They were r and omly divided into two subgroups : B1 was fed garlic for 10 months while B2 served as a control . Garlic decreased the serum cholesterol ( p less than 0.05 ) , triglycerides ( p less than 0.05 ) and low density lipoprotein ( p less than 0.05 ) while increasing the high-density fraction ( p less than 0.001 ) . The change reached statistically significant levels at the end of 8 months and persisted for the next 2 months of follow-up . Thus , the essential oil of garlic has shown a distinct hypolipidemic action in both healthy individuals and patients of coronary heart disease
Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .