Conclusions Piracetam plays a limited role in the rehabilitation of overall language impairment and only benefits written language ability at the end of trials .
Its effect on overall linguistic level and written language tends to emerge within a short period and declines thereafter
Background Aphasia is a common symptom in post-stroke patients .
Piracetam is a commonly used nootropic agent that promises various benefits to brain function , including language improvement .
Objective We performed a systematic review and meta- analysis to assess whether piracetam facilitates the rehabilitation of language performance in post-stroke patients .
Piracetam as an adjuvant to language therapy for aphasia: a randomized double-blind placebo-controlled pilot study.
OBJECTIVE To determine whether piracetam 4.8 g/day together with intensive language therapy improved language function more than language therapy alone . DESIGN Double-blind , placebo-controlled parallel group study . SETTING Referral speech and language clinic of a university department of neurology . PATIENTS Sixty-six in patients with aphasia present between 4 weeks and 36 months . INTERVENTIONS Intensive language therapy for 6 weeks in all patients . Thirty-two patients received piracetam 4.8 g daily and 34 patients received placebo . MAIN OUTCOME MEASURE The Aachen Aphasia Test ( AAT ) , a st and ardized procedure for evaluating the severity of aphasia , was performed at baseline and after 6 weeks ' treatment . RESULTS In 50 patients evaluated for efficacy , a trend toward improvement in the active group was observed in all subtests of the AAT . This trend was statistically significant for absolute differences in recovery of " written language " and " profile level . " CONCLUSION Piracetam appears to have a positive adjuvant effect on the recovery of aphasia in patients receiving intensive language therapy
Conclusions Piracetam plays a limited role in the rehabilitation of overall language impairment and only benefits written language ability at the end of trials .
Its effect on overall linguistic level and written language tends to emerge within a short period and declines thereafter
Background Aphasia is a common symptom in post-stroke patients .
Piracetam is a commonly used nootropic agent that promises various benefits to brain function , including language improvement .
Objective We performed a systematic review and meta- analysis to assess whether piracetam facilitates the rehabilitation of language performance in post-stroke patients .