Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .
[Prevention of allergy in infants. A prospective study of 159 high-risk children].
A total of 105 infants at " high risk " for developing allergy born in 1988 were studied prospect ively from birth to 18 months of age . The infants were recommended breastfeeding and /or hypoallergenic formula ( Nutramigen or Profylac ) combined with avoidance of solid foods the first six months of life . All mothers had unrestricted diet . Avoidance of daily exposure to tobacco smoking , furred pets and dust collecting material s in the bedroom was advised . This prevention group was compared to a control group consisting of 54 identically defined " high-risk " infants born in 1985 in the same area . All the infants had either severe single atopic predisposition combined with cord blood IgE > or = 0.5 KU/l or biparental atopic predisposition . The control group had unrestricted diet and was not advised about environmental factors . The cumulative incidence of atopic symptoms was significantly lower at 18 months in the prevention group ( 32 % ) compared with the control group ( 74 % ) ( p < 0.01 ) , due to reduced incidence of recurrent wheezing ( 13 % versus 37 % ; p < 0.01 ) , atopic dermatitis ( 14 % versus 31 % ; p < 0.01 ) , vomiting/diarrhoea ( 5 % versus 20 % ; p < 0.01 ) and infantile colic ( 9 % versus 24 % ; p < 0.01 ) . The cumulative incidence of food-allergy was significantly lower in the prevention group ( 6 % versus 17 % ; p < 0.05 ) . In both high-risk groups exposure to daily tobacco smoking increased the risk of recurrent wheezing significantly ( p < 0.01 ) . ( ABSTRACT TRUNCATED AT 250 WORDS
Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .