Overall , nicotine replacement therapy , bupropion , and varenicline have all proven their effectiveness at either promoting smoking abstinence or a significant reduction in cigarette use
Smoking cessation is a chronic issue surrounding individuals with schizophrenia .
It is estimated that up to 90 % of patients diagnosed with schizophrenia smoke cigarettes .
The purpose of this article is to provide a non systematic review of the efficacy of  smoking cessation interventions as well as to explore the potential neuropsychiatric adverse effects of these agents in patients with schizophrenia .
Varenicline plus healthy lifestyle intervention for smoking cessation in psychotic disorders.
BACKGROUND We were interested in exploring the efficacy and safety of varenicline as an adjunct to a healthy lifestyle intervention for smoking cessation among individuals with a severe mental illness . METHODS We used varenicline as an adjunct to a healthy lifestyle intervention in 14 smokers with a psychotic illness . RESULTS Overall , smoking cessation rates were 36 % at 3 months and 42 % at 6 months . The most commonly reported side effects were sleep disturbance and nausea . These tended to occur early in treatment , and patients responded to general measures of support and reassurance . Of the 14 participants , 1 dropped out because of psychiatric problems and 2 because of other side effects . CONCLUSIONS Varenicline appears to be an effective adjunct to a healthy lifestyle intervention for smokers with a psychotic illness . Although the results of this open study are encouraging , replication in an adequately powered , r and omized controlled trial is required before definitive conclusions can be drawn
Overall , nicotine replacement therapy , bupropion , and varenicline have all proven their effectiveness at either promoting smoking abstinence or a significant reduction in cigarette use
Smoking cessation is a chronic issue surrounding individuals with schizophrenia .
It is estimated that up to 90 % of patients diagnosed with schizophrenia smoke cigarettes .
The purpose of this article is to provide a non systematic review of the efficacy of  smoking cessation interventions as well as to explore the potential neuropsychiatric adverse effects of these agents in patients with schizophrenia .