The systemic inflammatory response was normalized before or on the seventh postoperative day .
Conclusions Hernia repair elicits a systemic inflammatory response characterized by an increase in CRP , IL-6 , leukocytes , neutrophils , IL-1 , IL-10 , fibrinogen , and α1-antitrypsin and a decrease in lymphocytes and albumin .
A higher inflammatory response was found after mesh repair compared with non-mesh repair and after open mesh repair compared with laparoscopic mesh repair
Purpose All surgical procedures elicit a complex systemic inflammatory response effectuated and modulated by cytokines .
The purpose of this systematic review was to present an overview of the inflammatory response and the serum markers associated with hernia repair and to compare the response between patients treated with and without mesh .
Early assessment of bilateral inguinal hernia repair: A comparison between the laparoscopic total extraperitoneal and Stoppa approaches
BACKGROUND : The present clinical trial was design ed to compare the results of bilateral inguinal hernia repair between patients who underwent the conventional Stoppa technique and laparoscopic total extraperitoneal repair ( LTE ) with a single mesh and without staple fixation . PATIENTS AND METHODS : This controlled , r and omised clinical trial was conducted at General Surgery and Trauma of the Clinics Hospital , Medical School , the University of São Paulo between September 2010 and February 2011 . Totally , 50 male patients , with a bilateral inguinal hernia , older than 25 years were considered eligible for the study . The following parameters were analysed during the early post-operative period : ( 1 ) The intensity of surgical trauma , operation time , C-reactive protein ( CRP ) levels , white blood cell count , bleeding and pain intensity ; ( 2 ) quality of life assessment ; and ( 3 ) post-operative complications . RESULTS : LTE procedure was longer than the Stoppa procedure ( 134.6 min ± 38.3 vs. 90.6 min ± 41.3 ; P < 0.05 ) . The levels of CRP were higher in the Stoppa group ( P < 0.05 ) but the number of leucocytes , haematocrit , and haemoglobin were similar between the groups ( P > 0.05 ) . There was no difference in pain during the 1st and 7th post-operative , physical functioning , physical limitation , the impact of pain on daily activities , and the Carolinas Comfort Scale during the 7th and 15th post-operative ( P > 0.05 ) . Complications occurred in 88 % of Stoppa group ( 22 patients ) and 64 % in LTE group ( 16 patients ) ( P < 0.05 ) . CONCLUSION : The comparative study between the Stoppa and LTE approaches for the bilateral inguinal hernia repair demonstrated that : ( 1 ) The LTE approach showed less surgical trauma despite the longer operation time ; ( 2 ) Quality of life during the early post-operative period were similar ; and ( 3 ) Complication rates were higher in the Stoppa group
The systemic inflammatory response was normalized before or on the seventh postoperative day .
Conclusions Hernia repair elicits a systemic inflammatory response characterized by an increase in CRP , IL-6 , leukocytes , neutrophils , IL-1 , IL-10 , fibrinogen , and α1-antitrypsin and a decrease in lymphocytes and albumin .
A higher inflammatory response was found after mesh repair compared with non-mesh repair and after open mesh repair compared with laparoscopic mesh repair
Purpose All surgical procedures elicit a complex systemic inflammatory response effectuated and modulated by cytokines .
The purpose of this systematic review was to present an overview of the inflammatory response and the serum markers associated with hernia repair and to compare the response between patients treated with and without mesh .