Subgroup analyses showed the most marked relation between sugar intakes and lipids in studies in which efforts were made to ensure an energy balance and when no difference in weight change was reported .
CONCLUSIONS Dietary sugars  influence blood pressure and serum lipids .
The relation is independent of effects of  sugars on body weight .
BACKGROUND Dietary sugars have been suggested as a cause of obesity , several chronic diseases , and a range of cardiometabolic risk factors , but there is no convincing evidence of a causal relation between sugars and risk factors other than body weight .
OBJECTIVE We conducted a systematic review and meta- analysis of r and omized controlled trials that examined effects of the modification of dietary free sugars on blood pressure and lipids .
Sucrose and various carbohydrate-containing foods and serum lipids in man.
The effects of several high carbohydrate foods on fasting serum cholesterol , phospholipids , and triglyceride levels were tested in 12 young men . The men were distributed into four groups , each of which was given a diet containing a different supplement . The four supplements ( 500 kcal of carbohydrate each ) contained , respectively , sucrose , wheat flour , mixed fruits , and mixed vegetables . Egg white was added as needed to equalize protein in all the supplements . In consecutive 2-week periods , the supplements were exchanged so that in four periods each group received every supplement . Fasting blood sample s were taken on the last 3 days of each period . There was no significant difference in serum cholesterol levels except for the vegetable diet , which produced much lower serum cholesterol than any of the other three diets . The serum phospholipids were also lower with the vegetable diet than with any of the other diets . No significant difference in serum triglycerides was found between the four diets . In a second similar experiment , diets containing sucrose , wheat flour , chickpeas , and a mixture of dry peas and beans were compared . No significant between-diets difference was found for either cholesterol , phospholipids , or triglycerides in this experiment . These results indicate that in 2-week dietary periods sucrose does not cause higher fasting serum cholesterol , phospholipids , or triglycerides than either wheat flour or dry leguminous seeds in amounts containing isocaloric quantities of starch . Am . J. Clin . Nutr . 27 : 1043 - 105 1 , 1974
Subgroup analyses showed the most marked relation between sugar intakes and lipids in studies in which efforts were made to ensure an energy balance and when no difference in weight change was reported .
CONCLUSIONS Dietary sugars  influence blood pressure and serum lipids .
The relation is independent of effects of  sugars on body weight .
BACKGROUND Dietary sugars have been suggested as a cause of obesity , several chronic diseases , and a range of cardiometabolic risk factors , but there is no convincing evidence of a causal relation between sugars and risk factors other than body weight .
OBJECTIVE We conducted a systematic review and meta- analysis of r and omized controlled trials that examined effects of the modification of dietary free sugars on blood pressure and lipids .