In breastfed infants , evidence suggests that a hypoallergenic maternal diet may be beneficial for reducing symptoms of colic .
In formula-fed infants , colic may improve after changing from a st and ard cow ’s milk formula to either a hydrolysed protein formula or a soy-based formula .
Fibre-supplemented formulae had no effect .
Infantile colic , the cause of 10–20 % of all early paediatrician visits , can lead to parental exhaustion and stress .
A systematic review was conducted to examine whether dietary change provides an effective therapy for  infantile colic .
Effectiveness of casein hydrolysate feedings in infants with colic
This study found that two casein hydrolysate formulas varying in composition were equally effective in managing  colicky symptoms associated with protein sensitivity . Both hydrolysate formulas were associated with a significant , comparable reduction in crying duration and intensity from baseline in 15 of 22 infants with complete data . Subsequent challenge data suggest that the population studied were infants experiencing colicky symptoms due to protein sensitivity . A greater proportion of infants showed a positive reaction ( ≥1.5h of crying/d ) to the protein challenges than the placebo challenge , and crying was rated as more intense during whey and milk protein challenges
In breastfed infants , evidence suggests that a hypoallergenic maternal diet may be beneficial for reducing symptoms of colic .
In formula-fed infants , colic may improve after changing from a st and ard cow ’s milk formula to either a hydrolysed protein formula or a soy-based formula .
Fibre-supplemented formulae had no effect .
Infantile colic , the cause of 10–20 % of all early paediatrician visits , can lead to parental exhaustion and stress .
A systematic review was conducted to examine whether dietary change provides an effective therapy for  infantile colic .