REVIEW ERS ' CONCLUSIONS Despite most of the included studies being of low quality , the results suggest that iodine supplementation , especially iodised oil , is an effective means of decreasing goitre rates and improving iodine status in children .
Indications of positive effects on physical and mental development and mortality were seen , although results were not always significant .
Adverse effects were generally minor and transient .
BACKGROUND Iodine deficiency is the main cause of potentially preventable mental retardation in childhood , as well as causing goitre and hypothyroidism in people of all ages .
It is still prevalent in large parts of the world .
OBJECTIVES To assess the effects of iodine supplementation overall , and of different forms and dosages of iodine supplementation separately , in the prevention of iodine deficiency disorders in children .
Iodized Oil as a Complement to Iodized Salt in Schoolchildren in Endemic Goiter in Romania
Objective : To evaluate the long-term efficacy and possible side effects of low doses of iodized oil on iodine nutrition and thyroid function in endemic goiter in Romania . Methods : R and om selection of 214 schoolchildren aged 6–14 years . Serial measurements of urinary iodine , thyroid volume with ultrasound , serum concentrations of thyrotropin , free thyroxine , thyroglobulin and thyroid autoantibodies before and up to 2 years after the oral administration of 200 mg iodine in iodized oil . Results : Urinary iodine concentrations indicated a moderate iodine deficiency before therapy , sharply increased soon after therapy and slowly decreased thereafter but remained within the normal range up to more than 1 year after therapy . The prevalence of goiter was 29 % before the administration of iodized oil and 9 % 1 year later . Thyroid function tests and autoantibodies were normal before and up to 2 years after therapy . Conclusion : A single dose of 200 mg iodine from oral Lipiodol ® appears adequate and safe for correcting moderate iodine deficiency in children
REVIEW ERS ' CONCLUSIONS Despite most of the included studies being of low quality , the results suggest that iodine supplementation , especially iodised oil , is an effective means of decreasing goitre rates and improving iodine status in children .
Indications of positive effects on physical and mental development and mortality were seen , although results were not always significant .
Adverse effects were generally minor and transient .
BACKGROUND Iodine deficiency is the main cause of potentially preventable mental retardation in childhood , as well as causing goitre and hypothyroidism in people of all ages .
It is still prevalent in large parts of the world .
OBJECTIVES To assess the effects of iodine supplementation overall , and of different forms and dosages of iodine supplementation separately , in the prevention of iodine deficiency disorders in children .