Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .
Prevalence and predictors of sub-optimal medication adherence among patients with severe mental illnesses in a tertiary psychiatric facility in Maiduguri, North-eastern Nigeria
Introduction Sub-optimal adherence constitutes a significant impediment to the management of severe mental illnesses ( SMIs ) as it negatively impacts on the course of the illness and the treatment outcome . In this study , the levels of adherence , prevalence and the predictors of sub-optimal adherence were assessed in a sub-Saharan African setting . Methods Three hundred and seventy ( 370 ) respondents with diagnoses of schizophrenia , bipolar disorder or severe depression were r and omly enrolled and interviewed at the out-patient department of the Federal Neuropsychiatric Hospital , Maiduguri in northeastern Nigeria . An anonymous sociodemographic question naire and a clinical proforma design ed by the authors ,  Oslo social support scale  and the  8-item Morisky Medication Adherence Scale ( MMAS-8 ) were used for data collection . Results The prevalence of sub-optimal adherence was 55.7 % . The independent predictors of sub-optimal adherence were ; seeking for traditional/ spiritual treatment ( Odds Ratio ( O.R. ) = 6.523 , 95 % C.I. = 3.773 - 11.279 , P = < 0.001 ) , male gender ( O.R. = 3.307 , 95 % C.I. = 1.907 - 5.737 , P = < 0.001 ) , low levels of insight ( O.R. = 1.753 , 95 C.I. = 1.220 - 2.519 , P = 0.002 ) , and low social support levels ( O.R. = 1.528 , 95 % C.I. = 1.097 - 2.129 , P = 0.012 ) . Conclusion Based on the outcome of the study , we recommend the development of psycho-educational programmes on adherence and the active involvement of the relations and significant others in the management of patients with SMIs in sub-Saharan Africa
Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .