SET was still beneficial for maximal and pain-free walking distances at 12 months , but it did not have a significant effect on quality of life parameters .
AUTHORS ' CONCLUSIONS SET has statistically significant benefit on treadmill walking distance ( maximal and pain-free ) compared with non-supervised regimens .
BACKGROUND Although supervised exercise therapy is considered to be of significant benefit for people with leg pain ( peripheral arterial disease ( PAD ) ) , implementing supervised exercise programs ( SETs ) in daily practice has limitations .
This is an up date of a review first published in 2006 .
OBJECTIVES The main objective of this review was to provide an accurate overview of studies evaluating the effects of supervised versus non-supervised exercise therapy on maximal walking time or distance on a treadmill for people with intermittent claudication .
Natural history of claudication: long-term serial follow-up study of 1244 claudicants.
OBJECTIVE The purpose of this study was to delineate the natural history of claudication and determine risk factors for ischemic rest pain ( IRP ) and ischemic ulceration ( IU ) among patients with claudication . METHODS We prospect ively collected data on 1244 men with claudication during a 15-year period , including demographics , clinical risk factors , and ankle-brachial index ( ABI ) .  We followed these patients serially with ABIs , self-reported walking distance ( WalkDist ) , and monitoring for IRP and IU .  We used Kaplan-Meier and proportional hazards modeling to find independent predictors of IRP and IU . RESULTS Mean follow-up was 45 months ; statistically valid follow-up could be carried out for as long as 12 years . ABI declined an average of 0.014 per year . WalkDist declined at an average rate of 9.2 yards per year . The cumulative 10-year risks of development of IU and IRP were 23 % and 30 % , respectively . In multivariate analysis using several clinical risk factors , we found that only DM ( relative risk [ RR ] , 1.8 ) and ABI ( RR , 2.2 for 0.1 decrease in ABI ) predicted the development of IRP . Similarly , only DM ( RR , 3.0 ) and ABI ( RR , 1.9 for 0.1 decrease in ABI ) were significant predictors of IU . CONCLUSION This large serial study of claudication is , to our knowledge , the longest of its kind . We documented an average rate of ABI decline of 0.014 per year and a decline in WalkDist of 9.2 yards per year . Two clinical factors , ABI and DM , were found to be associated with the development of IRP and IU . Our findings may be useful in predicting the clinical course of claudication
SET was still beneficial for maximal and pain-free walking distances at 12 months , but it did not have a significant effect on quality of life parameters .
AUTHORS ' CONCLUSIONS SET has statistically significant benefit on treadmill walking distance ( maximal and pain-free ) compared with non-supervised regimens .
BACKGROUND Although supervised exercise therapy is considered to be of significant benefit for people with leg pain ( peripheral arterial disease ( PAD ) ) , implementing supervised exercise programs ( SETs ) in daily practice has limitations .
This is an up date of a review first published in 2006 .
OBJECTIVES The main objective of this review was to provide an accurate overview of studies evaluating the effects of supervised versus non-supervised exercise therapy on maximal walking time or distance on a treadmill for people with intermittent claudication .