Conclusions This systemic review shows that preoperative interventions can be beneficial in improving wound healing and scar formation .
In selected cases , wound healing was found to benefit from a higher preoperative body temperature , topical vitamin E application , and low patient stress levels .
Background Poor wound healing and scar formation  remain critical problems in daily surgical practice .
Generally , most attention is paid to intra- and postoperative interventions to improve wound healing after surgery , while preoperative interventions remain unsatisfactorily explored .
Objectives In this systematic review , the available literature on the beneficial effects of preoperative interventions on wound healing and scar formation have been summarized and compared .
A prospective study in children: Pre- and post-surgery use of vitamin E in surgical incisions.
BACKGROUND One of the main problems of elective surgery is the cosmetic result . OBJECTIVE This prospect i ve controlled study aims to determine the effects of topical vitamin E on cosmetic results in children . METHODS A single-blind study was carried out . Topical vitamin E was used on the intended incision site for at least 15 days , thrice daily , before surgery and for at least 30 days , twice daily , after surgery ( group A ) . The control group received topical petrolatum-based ointment ( group B ) . RESULTS No patients in group A developed keloids . A total of 96 % of patients ( or parents ) considered the cosmetic results very good . No patients had wound infection . In the control group , only 78 % of patients ( or parents ) considered the cosmetic results very good and 13 ( 6.5 % ) patients developed keloids after 6 months . There were no cases of wound infection . CONCLUSION Topical vitamin E before and after surgery improved surgical wound healing and improved cosmetic results
Conclusions This systemic review shows that preoperative interventions can be beneficial in improving wound healing and scar formation .
In selected cases , wound healing was found to benefit from a higher preoperative body temperature , topical vitamin E application , and low patient stress levels .
Background Poor wound healing and scar formation  remain critical problems in daily surgical practice .
Generally , most attention is paid to intra- and postoperative interventions to improve wound healing after surgery , while preoperative interventions remain unsatisfactorily explored .
Objectives In this systematic review , the available literature on the beneficial effects of preoperative interventions on wound healing and scar formation have been summarized and compared .