In conclusion , decrease in muscle strength and muscle mass in older patients is dependent on the type of admission .
HIGHLIGHTSPhysical inactivity during hospitalization is associated with detrimental outcome .Muscle strength and muscle mass decreased in electively admitted older patients .Muscle strength and muscle mass did not change in acutely admitted older patients
ABSTRACT Hospitalization may induce a decrease of muscle strength and muscle mass in older patients due to physical inactivity , malnutrition and diseases , negatively affecting health outcome .
We aim ed to examine the literature on change in muscle strength and muscle mass in older patients during hospitalization .
A pilot study of anabolic steroids in elderly patients with hip fractures.
OBJECTIVE To determine the safety and efficacy of the anabolic steroid n and rolone in elderly patients with hip fractures . DESIGN A r and omized double-blind placebo-controlled trial . SETTING The orthopedic ward of a university teaching hospital . PARTICIPANTS 29 frail elderly females with hip fractures . INTERVENTION Subjects received n and rolone 2 mg/kg ( n = 15 ) or placebo ( n = 14 ) by weekly injection for 4 weeks or until discharge . MEASURES Baseline functional status was assessed by the Lawton-Brody ADL and IADL . Hemoglobin , transferrin , thyroid-binding prealbumin , albumin , liver function tests , creatinine , weight , MAMC , bioelectric impedance , st and ard anthropometrics and grip strength were measured at baseline and weekly intervals . Rehabilitation parameters and length of stay were recorded . RESULTS The placebo and n and rolone groups were similar in age , although the control group had slightly higher baseline ADL scores . There was no difference between groups in biochemical parameters , anthropometrics , body composition , grip strength , rehabilitation end points or length of stay . One subject in the n and rolone group had a doubling of AST and was withdrawn from the study . CONCLUSIONS N and rolone can be given safely to frail elderly subjects with hip fractures but is likely to be of minimal benefit at the doses we employed
In conclusion , decrease in muscle strength and muscle mass in older patients is dependent on the type of admission .
HIGHLIGHTSPhysical inactivity during hospitalization is associated with detrimental outcome .Muscle strength and muscle mass decreased in electively admitted older patients .Muscle strength and muscle mass did not change in acutely admitted older patients
ABSTRACT Hospitalization may induce a decrease of muscle strength and muscle mass in older patients due to physical inactivity , malnutrition and diseases , negatively affecting health outcome .
We aim ed to examine the literature on change in muscle strength and muscle mass in older patients during hospitalization .