Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .
Results of sacral neuromodulation therapy for urinary voiding dysfunction: outcomes of a prospective, worldwide clinical study.
PURPOSE This 5-year , prospect i ve , multicenter trial evaluated the long-term safety and efficacy of sacral neuromodulation in patients with refractory urge incontinence , urgency frequency and retention . MATERIAL S AND METHODS A total of 17 centers worldwide enrolled 163 patients ( 87 % female ) . Following test stimulation 11 patients declined implantation and 152 underwent implantation using InterStim .  Of those treated with implantation 96 ( 63.2 % ) had urge incontinence , 25 ( 16.4 % ) had urgency frequency and 31 ( 20.4 % ) had retention . Voiding diaries were collected annually for 5 years . Clinical success was defined as 50 % or greater improvement from baseline in primary voiding diary variable(s ) . RESULTS Data for all implanted cases were reported . For patients with urge incontinence mean leaking episodes per day decreased from 9.6 + /- 6.0 to 3.9 + /- 4.0 at 5 years . For patients with urgency frequency mean voids per day decreased from 19.3 + /- 7.0 to 14.8 + /- 7.6 , and mean volume voided per void increased from 92.3 + /- 52.8 to 165.2 + /- 147.7 ml . For patients with retention the mean volume per catheterization decreased from 379.9 + /- 183.8 to 109.2 + /- 184.3 ml , and the mean number of catheterizations decreased from 5.3 + /- 2.8 to 1.9 + /- 2.8 . All changes were statistically significant ( p < 0.001 ) . No life threatening or irreversible adverse events occurred . In 102 patients 279 device or therapy related adverse events were observed . At 5 years after implantation 68 % of patients with urge incontinence , 56 % with urgency frequency and 71 % with retention had successful outcomes . CONCLUSIONS This long-term study demonstrates that InterStim therapy is safe and effective for restoring voiding in appropriately selected cases refractory to other forms of treatment
Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .