We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .
Omega 3 fatty acids induce a marked reduction of apolipoprotein B48 when added to fluvastatin in patients with type 2 diabetes and mixed hyperlipidemia: a preliminary report
BackgorundMixed hyperlipidemia is common in patients with diabetes .  Statins , the choice drugs , are effective at reducing lipoproteins that contain apolipoprotein B100 , but they fail to exert good control over intestinal lipoproteins , which have an atherogenic potential . We describe the effect of prescription omega 3 fatty acids on the intestinal lipoproteins in patients with type 2 diabetes who were already receiving fluvastatin 80 mg per day . Methods Patients with type 2 diabetes and mixed hyperlipidemia were recruited .  Fasting lipid profile was taken when patients were treated with diet , diet plus 80 mg of fluvastatin and diet plus fluvastatin 80 mg and 4 g of prescription omega 3 fatty acids . The intestinal lipoproteins were quantified by the fasting concentration of apolipoprotein B48 using a commercial ELISA . Results The addition of 4 g of prescription omega 3 was followed by significant reductions in the levels of triglycerides , VLDL triglycerides and the triglyceride/HDL cholesterol ratio , and an increase in HDL cholesterol ( P < 0.05 ) . Fluvastatin induced a reduction of 26 % in B100 ( P < 0.05 ) and 14 % in B48 ( NS ) . However , the addition of omega 3 fatty acids enhanced this reduction to 32 % in B100 ( NS ) and up to 36 % in B48 ( P < 0.05 ) . Conclusion Our preliminary findings therefore suggest an additional benefit on postpr and ial atherogenic particles when omega 3 fatty acids are added to st and ard treatment with fluvastatin
We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .