Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .
Effects of alternate-day fasting or daily calorie restriction on body composition, fat distribution, and circulating adipokines: Secondary analysis of a randomized controlled trial.
BACKGROUND & AIMS Indirect comparisons suggest that alternate-day fasting ( ADF ) may produce greater improvements in body composition , fat distribution , and /or the adipokine profile compared to daily calorie restriction ( CR ) , but this has not been tested directly . In a pre-planned secondary analysis of a r and omized controlled trial , we compared changes in the VAT : SAT ratio , FFM : total mass ratio , and the adipokine profile between ADF and CR . METHODS Overweight and obese participants ( n = 100 ) were r and omized to 1 ) ADF ( alternating every 24-h between consuming 25 % or 125 % of energy needs ) ; 2 ) CR ( consuming 75 % of needs every day ) ; or 3 ) control ( consuming 100 % of needs every day ) for 24 wk . RESULTS The VAT : SAT ratio did not change in any group . The FFM : total mass ratio increased in both ADF ( 0.03 ± 0.00 ) and CR ( 0.03 ± 0.01 ) compared to the control group ( P < 0.01 ) , with no differences between the intervention groups . Circulating leptin decreased in both the ADF group ( -18 ± 6 % ) and CR group ( -31 ± 10 % ) relative to the control group ( P < 0.05 ) , with no differences between the intervention groups . Circulating levels of adiponectin , resistin , IL-6 , and TNF-α did not change in either intervention group relative to the control group . CONCLUSION ADF and CR similarly improve the FFM : total mass ratio and reduce leptin after a 24-wk intervention . TRIAL REGISTRATION Clinical trials.gov , number NCT00960505
Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .