REVIEW ER 'S CONCLUSIONS There is no evidence to support feeding with a hydrolysed formula for the prevention of allergy in preference to exclusive breast feeding .
In high risk infants who are unable to be completely breast fed , there is evidence that prolonged feeding with a hydrolysed compared to a cow 's milk formula reduces infant and childhood allergy and infant CMA .
BACKGROUND Allergies and food reactions are common and may be associated with foods including adapted cow 's milk formulas .
Formulas containing hydrolysed proteins have been used to treat infants with allergy or food intolerance , and have been advocated for prevention of allergy and food intolerance in infants .
OBJECTIVES To determine whether use of hydrolysed formulas for infant feeding prevents allergy and food intolerance .
If hydrolysed formulas are effective , to determine what type of hydrolysed formula is most effective including extensively and partially hydrolysed formulas .
To determine which infants benefit including infants at low or high risk of allergy and infants receiving early , short term or prolonged formula feeding .
Individualized protein fortification of human milk for preterm infants: comparison of ultrafiltrated human milk protein and a bovine whey fortifier.
BACKGROUND To improve the nutritional management of pre-term infants , a new individualized human milk fortification system based on presupplementation milk protein analyses was evaluated . METHODS In an open , prospect i ve , r and omized multicenter study , 32 healthy preterm infants ( birth weights , 920 - 1750 g ) were enrolled at a mean of 21 days of age ( range , 9 - 36 days ) when tolerating exclusive enteral feedings of 150 ml/kg per day . All infants were fed human milk and were r and omly allocated to fortification with a bovine whey protein fortifier ( n = 16 ) or ultrafiltrated human milk protein ( n = 16 ) . All human milk was analyzed for protein content before fortification with the goal of a daily protein intake of 3.5 g/kg . During the study period ( mean , 24 days ) daily aliquots of the fortified milk were obtained for subsequent analyses of the protein content . RESULTS Both fortifiers were well tolerated , and growth gain in weight , length , and head circumference , as well as final prepr and ial concentrations of serum urea , transthyretin , transferrin , and albumin were similar in both groups . The ultimate estimated protein intake was equivalent in both groups ( mean 3.1+/-0.1 g/kg per day ) . Serum amino acid profiles were similar in both feeding groups , except for threonine ( significantly higher in the bovine fortifier group ) and proline and ornithine ( significantly higher in the human milk protein group ) . CONCLUSIONS Protein analyses of the milk before individual fortification provides a new tool for an individualized feeding system of the preterm infant . The bovine whey protein fortifier attained biochemical and growth results similar to those found in infants fed human milk protein exclusively with the corresponding protein intakes
REVIEW ER 'S CONCLUSIONS There is no evidence to support feeding with a hydrolysed formula for the prevention of allergy in preference to exclusive breast feeding .
In high risk infants who are unable to be completely breast fed , there is evidence that prolonged feeding with a hydrolysed compared to a cow 's milk formula reduces infant and childhood allergy and infant CMA .
BACKGROUND Allergies and food reactions are common and may be associated with foods including adapted cow 's milk formulas .
Formulas containing hydrolysed proteins have been used to treat infants with allergy or food intolerance , and have been advocated for prevention of allergy and food intolerance in infants .
OBJECTIVES To determine whether use of hydrolysed formulas for infant feeding prevents allergy and food intolerance .
If hydrolysed formulas are effective , to determine what type of hydrolysed formula is most effective including extensively and partially hydrolysed formulas .
To determine which infants benefit including infants at low or high risk of allergy and infants receiving early , short term or prolonged formula feeding .