Endurance training alone was found to increase both lower extremity strength and endurance capacity .
Colorectal cancer surgery results in considerable postoperative morbidity , mortality and reduced quality of life .
As many patients will undergo additional (neo)adjuvant therapy , it is imperative that each individual optimize their physical function .
To eluci date the potential of exercise in patient optimization , we investigated the evidence for an exercise program before and after surgical treatment in colorectal cancer patients .
The Impact of Postoperative Complications on Long-term Quality of Life After Curative Colorectal Cancer Surgery
Objective : To investigate the effect that complications have on patients ' long-term quality of life ( QoL ) after curative colorectal cancer surgery .  Background : Colorectal cancer surgery is a high risk , with approximately 1 in 3 patients suffering a complication . The long-term consequences of postoperative complications are important but have poorly been documented . Methods : The MRC-CLASICC trial ( laparoscopic-assisted vs open surgery for colorectal cancer ) included prospect i ve evaluation of QoL using vali date d scoring question naires : EORTC QLQ-C30/CR38 and EQ5D . These were used to compare QoL at 3 , 6 , 18 , and 36 months to baseline values for patients categorized into 2 groups : ( i ) those suffering any complication and ( ii ) those suffering any of 5 common complications ( wound , chest , anastomotic leak , hemorrhage , and cardiac event ) . Results : A total of 614 of 794 CLASICC patients were suitable for inclusion . Complications occurred in 215 ( 35.0 % ) patients , including : wound complications ( 61 , 9.9 % ) , chest infection ( 50 , 8.1 % ) , anastomotic leak ( 27 , 4.4 % ) , hemorrhage ( 14 , 2.3 % ) , and cardiac event ( 26 , 4.2 % ) . Significant long-term differences in QoL between patients with and without complications were found for Physical and Social Function , Role Functioning , and Body Image on EORTC QLQ-C30/QLQ-CR38 analysis and Mobility , Self-care , and Pain/Discomfort on EQ5D analysis . No significant differences were seen for emotional/cognitive functioning , global QoL , financial difficulties , or future perspectives . Risk factors of age , gender , ASA ( American Society of Anesthesiologists ) grade , and stoma moderated the impact of complications in the short- to medium-term QoL , but had less influence on long-term QoL. Conclusions : Postoperative complications have adverse effects on long-term QoL , particularly for Physical , Role and Social Functioning , and Body Image , as well as for Mobility , Self-care , and Pain/Discomfort . These findings should inform future preoperative counseling and health care planning
Endurance training alone was found to increase both lower extremity strength and endurance capacity .
Colorectal cancer surgery results in considerable postoperative morbidity , mortality and reduced quality of life .
As many patients will undergo additional (neo)adjuvant therapy , it is imperative that each individual optimize their physical function .
To eluci date the potential of exercise in patient optimization , we investigated the evidence for an exercise program before and after surgical treatment in colorectal cancer patients .