Psychosocial factors associated with pain-related interference included depression , catastrophising , fear avoidance , lower self-efficacy and worse mental well-being .
Conclusions Pain in IBD is significantly associated with cognitive and behavioural factors as well as low mood .
Objective Pain is frequently reported by patients with inflammatory bowel disease ( IBD ) .
Pain in IBD is not fully explained by disease activity or other clinical findings , and a recent systematic review suggested that psychosocial factors have an important role in IBD-pain .
The aim of this study was to investigate psychosocial factors associated with pain in IBD .
Assessing telephone-delivered cognitive–behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial
Objective To evaluate the clinical effectiveness of two modes of cognitive – behavioural therapy ( CBT ) for IBS compared with treatment as usual ( TAU ) in refractory IBS . Design A three-arm r and omised controlled trial assessing telephone-delivered CBT ( TCBT ) , web-based CBT ( WCBT ) with minimal therapist support , and TAU . Blinding participants and therapists was not possible . Chief investigator , assessors and statisticians were blinded . Participants were adults with refractory IBS ( clinical ly significant symptoms for ≥12 months despite first-line therapies ) , recruited by letter and opportunistically from 74 general practice s and three gastroenterology centres in London and South of Engl and between May 2014 to March 2016 . Co- primary outcomes were IBS Symptom Severity Score ( IBS-SSS ) and Work and Social Adjustment Scale ( WSAS ) at 12 months . Results 558/1452 ( 38.4 % ) patients screened for eligibility were r and omised : 76 % female : 91 % white : mean age 43 years . ( 391/558 ) 70.1 % completed 12 months of follow-up . Primary outcomes : Compared with TAU ( IBS-SSS 205.6 at 12 months ) , IBS-SSS was 61.6 ( 95 % CI 33.8 to 89.5 ) points lower ( p<0.001 ) in TCBT and 35.2 ( 95 % CI 12.6 to 57.8 ) points lower ( p=0.002 ) in WCBT at 12 months . Compared with TAU ( WSAS score 10.8 at 12 months ) WSAS was 3.5 ( 95 % CI 1.9 to 5.1 ) points lower ( p<0.001 ) in TCBT and 3.0 ( 95 % CI 1.3 to 4.6 ) points lower ( p=0.001 ) in WCBT . All secondary outcomes showed significantly greater improvement ( p≤0.002 ) in CBT arms compared with TAU . There were no serious adverse reactions to treatment . Conclusion Both CBT interventions were superior to TAU up to 12 months of follow-up . Trial registration number IS RCT N44427879
Psychosocial factors associated with pain-related interference included depression , catastrophising , fear avoidance , lower self-efficacy and worse mental well-being .
Conclusions Pain in IBD is significantly associated with cognitive and behavioural factors as well as low mood .
Objective Pain is frequently reported by patients with inflammatory bowel disease ( IBD ) .
Pain in IBD is not fully explained by disease activity or other clinical findings , and a recent systematic review suggested that psychosocial factors have an important role in IBD-pain .
The aim of this study was to investigate psychosocial factors associated with pain in IBD .