Sensitivity analyses and meta-regression for hemoglobin suggested a higher response with lower trial quality ( suboptimal allocation concealment and blinding ) , use of condiments , and sodium iron edetate and a lower response when adults were included .
Consumption of iron-fortified foods results in an improvement in hemoglobin , serum ferritin , and iron nutriture and a reduced risk of remaining anemic and iron deficient
BACKGROUND The utility of iron fortification of food to improve iron deficiency , anemia , and biological outcomes is not proven unequivocally .
Dual fortification of salt with iron and iodine in women and children in rural Ghana.
OBJECTIVE To test the efficacy of double-fortified salt ( DFS ) on the  anaemia and iodine deficiency ( ID ) status of women and their children . DESIGN Double-blind r and omised controlled trial . SETTING Sekyere West District of Ghana . SUBJECTS In this eight-month trial , mildly anaemic or non-anaemic , non-pregnant , non-lactating women were r and omised into three groups receiving : DFS plus weekly placebo ( n = 61 ) ; iodised salt plus weekly 70 mg iron supplement ( n = 65 ) ; or iodised salt ( IS ) plus weekly placebo ( control group , n = 58 ) . Correspondingly , their mildly anaemic and non-anaemic children aged 1 - 5 years were r and omised into two groups receiving either the DFS ( n = 23 ) or IS alone ( control group , n = 59 ) . RESULTS At the end of the intervention , prevalence of anaemia in women remained unchanged in the DFS or IS plus weekly iron supplement group , but significantly increased by 19.5 % in the control group ( P = 0.039 ) . In children , prevalence of anaemia in the DFS group significantly decreased by 21.7 % ( P = 0.025 ) while no change was observed in the control group . ID decreased significantly in all groups of women ( P < 0.001 ) and children ( P < 0.05 ) , with no difference among groups of women and children . CONCLUSION While the use of DFS prevented anaemia in women , it had a significant role in both the prevention and treatment of anaemia in children . Both the DFS and IS significantly reduced ID in women and children to a similar degree
Sensitivity analyses and meta-regression for hemoglobin suggested a higher response with lower trial quality ( suboptimal allocation concealment and blinding ) , use of condiments , and sodium iron edetate and a lower response when adults were included .
Consumption of iron-fortified foods results in an improvement in hemoglobin , serum ferritin , and iron nutriture and a reduced risk of remaining anemic and iron deficient
BACKGROUND The utility of iron fortification of food to improve iron deficiency , anemia , and biological outcomes is not proven unequivocally .