Subgroup analysis suggested the existence of liver disease at baseline , synbiotics supplementation and duration of supplementation ≥ 8 weeks result ed in more pronounced improvement in liver function enzymes than their counterparts .
Conclusions Probiotics and synbiotics may be suggested as supplements to improve serum concentration of liver enzymes , especially when synbiotics administered for a period ≥ 8 weeks and in individuals with liver disease
Purpose The gut – liver interaction suggests that modification of gut bacterial flora using probiotics and synbiotics may improve liver function .
This systematic review and meta- analysis aim ed to clarify the effect of probiotics and synbiotics consumption on the serum concentration of liver function enzymes .
Safety and tolerance of Lactobacillus reuteri supplementation to a population infected with the human immunodeficiency virus.
Probiotic supplementation may provide health benefits , especially for individuals with an underlying disease state that makes them more susceptible to infections . The purpose of this experiment was to evaluate the safety and tolerance of Lactobacillus reuteri ingestion by subjects infected with the human immunodeficiency virus ( HIV ) . Thirty-nine subjects consumed a freeze-dried preparation of L. reuteri or a placebo for 21 days in a double-masked , parallel design experiment . Serum chemistry , haematology , immune profile , urinalysis , physical examination , gastrointestinal tolerance and faecal microbiota data were collected . No clinical ly significant changes were noted in any of the safety parameters measured . Overall , tolerance was good in both groups . Consumption of L. reuteri tended to increase faecal levels of L. reuteri on days 7 , 14 and 21 of treatment feeding ( P < 0.06 , P < 0.11 and P = 0.05 , respectively ) . However , faecal levels of L. reuteri and total Lactobacillus species were lower than levels previously observed in healthy male adults . Overall , this study documents that L. reuteri may be fed to HIV-positive individuals at 1 x 10(10 ) colony forming units/day without any clinical ly significant safety or tolerance problems
Subgroup analysis suggested the existence of liver disease at baseline , synbiotics supplementation and duration of supplementation ≥ 8 weeks result ed in more pronounced improvement in liver function enzymes than their counterparts .
Conclusions Probiotics and synbiotics may be suggested as supplements to improve serum concentration of liver enzymes , especially when synbiotics administered for a period ≥ 8 weeks and in individuals with liver disease
Purpose The gut – liver interaction suggests that modification of gut bacterial flora using probiotics and synbiotics may improve liver function .
This systematic review and meta- analysis aim ed to clarify the effect of probiotics and synbiotics consumption on the serum concentration of liver function enzymes .