Some studies suggest that testosterone therapy has additional effects , which include increased bone mineral density and decreased serum high-density lipoprotein ( HDL ) cholesterol .
The clinical sequelae of oestrogen deficiency during menopause are undoubted .
However , the pathophysiological role of testosterone during the menopause is less clear .
Several r and omized , placebo-controlled clinical trials suggest that testosterone therapy improves sexual function in postmenopausal women .
Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis.
OBJECTIVE : To examine the possible beneficial effect of and rogens in postmenopausal women with active rheumatoid arthritis . METHODS : 107 women participated in a double blind placebo controlled trial to evaluate the effect of 50 mg testosterone propionate intramuscularly every two weeks for one year . RESULTS : An improvement in ESR , Dutch health assessment question naire , and pain was noted . In addition , 21 % of patients treated with testosterone fulfilled the ACR improvement criteria after one year , versus only 4 % of the placebo group . The treatment was well tolerated . CONCLUSIONS : Testosterone may improve the general wellbeing of postmenopausal women with active rheumatoid arthritis
Some studies suggest that testosterone therapy has additional effects , which include increased bone mineral density and decreased serum high-density lipoprotein ( HDL ) cholesterol .
The clinical sequelae of oestrogen deficiency during menopause are undoubted .
However , the pathophysiological role of testosterone during the menopause is less clear .
Several r and omized , placebo-controlled clinical trials suggest that testosterone therapy improves sexual function in postmenopausal women .