Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .
Chronic testosterone cypionate therapy in men with secondary impotence.
There have not been studies assessing the effects of chronic testosterone cypionate ( TC ) therapy on circulating levels of testosterone ( T ) , estradiol ( E2 ) , free T , bioavailable T ( BAT ) , luteinizing hormone ( LH ) , and sexual function in impotent men with low T levels . This study was a double-blind crossover using 200 mg of TC or placebo given intramuscularly every 14 days for six injections and the other medication given for six doses . Blood was drawn before each injection . Mean concentrations of T , E2 , free T , and BAT were the same on TC or on placebo , but serum LH was significantly suppressed during intramuscular TC . With TC statistically significant improvements in libido and in potency were noted . Five of the men were able to have vaginal sex while taking TC . TC injections every 14 days do not appear to maintain increased T concentrations for 2 full weeks , and other dosage/injection schedules are being evaluated , but there were improvements in libido and potency
Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .