Changes in FOX did not reach the level of statistical significance .
Finding showed that EGCG intake moderately accelerates EE and reduces RQ .
The analyses revealed that the EGCG result ed in difference in RQ and EE but the effect on the other measures of energy metabolism was relatively mild .
Possibly , EGCG alone has the potential to increase metabolic rate at 300 mg dose .
Collectively , the outcome supports the findings that EGCG has an effect on metabolic parameters .
Green tea catechins ( GTCs ) are known to improve fat oxidation ( FOX ) during fasted , rested and exercise conditions wherein epigallocatechin-3-gallate ( EGCG ) is thought to be the most pharmacologically active and has been studied extensively .
From the available data of r and omized controlled trials ( RCTs ) on EGCG , we carried out a systematic review and meta- analysis to eluci date whether EGCG consumption indeed increase energy expenditure ( EE ) and promote FOX .
Epigallocatechin-3-gallate increases maximal oxygen uptake in adult humans.
UNLABELLED Epigallocatechin-3-gallate ( EGCG ) , a component of green tea , increases endurance performance in animals and promotes fat oxidation during cycle ergometer exercise in adult humans . PURPOSE We have investigated the hypothesis that short-term consumption of EGCG delays the onset of the ventilatory threshold ( VT ) and increases maximal oxygen uptake ( VO2max ) . METHODS In this r and omized , repeated- measures , double-blind study , 19 healthy adults ( 11 males and 8 females , age = 26 ± 2 yr ( mean ± SE ) ) received seven placebo  or seven EGCG ( 135-mg ) pills . Forty-eight hours before data collection , participants began consuming three pills per day ; the last pill was taken 2 h before exercise testing . VT and VO2max were determined from breath-by-breath indirect calorimetry data collected during continuous incremental stationary cycle ergometer exercise ( 20 - 35 W·min(-1 ) ) , from rest until volitional fatigue . Each condition/exercise test was separated by a minimum of 14 d. RESULTS Compared with placebo , short-term EGCG consumption increased VO2max ( 3.123 ± 0.187 vs 3.259 ± 0.196 L·min(-1 ) , P = 0.04 ) . Maximal work rate ( 301 ± 15 vs 301 ± 16 W , P = 0.98 ) , maximal RER ( 1.21 ± 0.01 vs 1.22 ± 0.02 , P = 0.27 ) , and maximal HR were unaffected ( 180 ± 3 vs 180 ± 3 beats·min(-1 ) , P = 0.87 ) . In a subset of subjects ( n = 11 ) , maximal cardiac output ( determined via open-circuit acetylene breathing ) was also unaffected by EGCG ( 29.6 ± 2.2 vs 30.2 ± 1.4 L·min(-1 ) , P = 0.70 ) . Contrary to our hypothesis , EGCG  decreased VO2 at VT ( 1.57 ± 0.11 vs 1.48 ± 0.10 L·min(-1 ) ) , but this change was not significant ( P = 0.06 ) . CONCLUSIONS Short-term consumption of EGCG  increased VO2max without affecting maximal cardiac output , suggesting that EGCG may increase arterial-venous oxygen difference
Changes in FOX did not reach the level of statistical significance .
Finding showed that EGCG intake moderately accelerates EE and reduces RQ .
The analyses revealed that the EGCG result ed in difference in RQ and EE but the effect on the other measures of energy metabolism was relatively mild .
Possibly , EGCG alone has the potential to increase metabolic rate at 300 mg dose .
Collectively , the outcome supports the findings that EGCG has an effect on metabolic parameters .
Green tea catechins ( GTCs ) are known to improve fat oxidation ( FOX ) during fasted , rested and exercise conditions wherein epigallocatechin-3-gallate ( EGCG ) is thought to be the most pharmacologically active and has been studied extensively .
From the available data of r and omized controlled trials ( RCTs ) on EGCG , we carried out a systematic review and meta- analysis to eluci date whether EGCG consumption indeed increase energy expenditure ( EE ) and promote FOX .