All eight domains were predictive for at least one of the investigated outcomes but the results were quite variable across studies .
Physical function and nutritional status were the domains most often associated with mortality and systemic treatment-related outcomes , and the domain physical function was most often associated with postoperative complications .
Overall , this review demonstrates that the GA should minimally consist of physical function and nutritional status , when the aim is to predict patients -related outcomes of older patients with cancer , although the results are quite heterogeneous .
BACKGROUND A geriatric assessment ( GA ) is increasingly used to help guide treatment decisions in older patients with cancer .
However , there is no consensus regarding which domains should be included in the GA .
In addition , the field of geriatric oncology moves very fast and as a result many new studies have been published since the last review in 2015 .
Therefore , the objective of this systematic review is to evaluate which domains of the GA could predict patient-related treatment outcomes of older patients with cancer and thereby should be included in a GA .
Poor nutritional status is associated with other geriatric domain impairments and adverse postoperative outcomes in onco-geriatric surgical patients - A multicentre cohort study.
BACKGROUND Nutritional status ( NS ) , though frequently affected in onco-geriatric patients , is no st and ard part of a geriatric assessment . The aim of this study was to analyse the association between a preoperatively impaired NS and geriatric domain impairments and adverse postoperative outcomes in onco-geriatric surgical patients . METHODS 309 patients ≥70 years undergoing surgery for solid tumours were prospect ively recruited .  Nine screening tools were preoperatively administered as part of a geriatric assessment . NS was based on BMI , weight loss and food intake . Odds ratio 's ( OR ) and 95 % confidence intervals ( 95 % CI ) were estimated using logistic regression analysis . The occurrence of 30-day adverse postoperative outcomes was recorded . RESULTS At a median age of 76 years , 107 patients ( 34.6 % ) had an impaired NS . Decreased performance status and depression were associated with an impaired NS , when adjusted for tumour characteristics and comorbidities ( ORPS>1 3.46 ; 95 % CI 1.56 - 7.67 . ORGDS>5 2.11 ; 95 % CI 1.05 - 4.26 ) . An impaired NS was an independent predictor for major complications ( OR 3.3 ; 95 % CI 1.6 - 6.8 ) . Ten out of 11 patients who deceased had an impaired NS . CONCLUSION An impaired NS is prevalent in onco-geriatric patients considered to be fit for surgery . It is associated with decreased performance status and depression . An impaired NS is a predictor for adverse postoperative outcomes . NS should be incorporated in a geriatric assessment
All eight domains were predictive for at least one of the investigated outcomes but the results were quite variable across studies .
Physical function and nutritional status were the domains most often associated with mortality and systemic treatment-related outcomes , and the domain physical function was most often associated with postoperative complications .
Overall , this review demonstrates that the GA should minimally consist of physical function and nutritional status , when the aim is to predict patients -related outcomes of older patients with cancer , although the results are quite heterogeneous .
BACKGROUND A geriatric assessment ( GA ) is increasingly used to help guide treatment decisions in older patients with cancer .
However , there is no consensus regarding which domains should be included in the GA .
In addition , the field of geriatric oncology moves very fast and as a result many new studies have been published since the last review in 2015 .
Therefore , the objective of this systematic review is to evaluate which domains of the GA could predict patient-related treatment outcomes of older patients with cancer and thereby should be included in a GA .