While no clinical trial to date has specifically targeted fatigue , r and omized controlled trials , systematic review s , and meta-analyses indicate that treatment modalities studied in the context of other fibromyalgia symptoms could also improve fatigue .
Fatigue is a disabling , multifaceted symptom that is highly prevalent and stubbornly persistent .
Although fatigue is a frequent complaint among patients with fibromyalgia , it has not received the same attention as pain .
Reasons for this include lack of st and ardized nomenclature to communicate about fatigue , lack of evidence -based guidelines for fatigue assessment , and a deficiency in effective treatment strategies .
Fatigue does not occur in isolation ; rather , it is present concurrently in varying severity with other fibromyalgia symptoms such as chronic widespread pain , unrefreshing sleep , anxiety , depression , cognitive difficulties , and so on .
Survey-based and preliminary mechanistic studies indicate that multiple symptoms feed into fatigue and it may be associated with a variety of physiological mechanisms .
Effects of Panax ginseng extract in patients with fibromyalgia: a 12-week, randomized, double-blind, placebo-controlled trial.
The purpose of the study was to evaluate the efficacy of an extract of Panax ginseng in patients with fibromyalgia . A r and omized , double-blind , controlled clinical trial was carried out over 12 weeks to compare the effects of P. ginseng ( 100 mg/d ) with amitriptyline ( 25 mg/d ) and placebo in 38 patients with fibromyalgia : 13 in Group I ( amitriptyline ) , 13 in Group II ( placebo ) , and 12 in Group III ( P. ginseng ) . Ratings on the Visual Analogue Scale ( VAS ) revealed a reduction in pain in the P. ginseng group ( p < .0001 ) , an improvement in fatigue ( p < .0001 ) and an improvement in sleep ( p < .001 ) , with respect to baseline characteristics , but there were no differences between the three groups . With respect to anxiety , improvements occurred in the P. ginseng group compared to baseline ( p < .0001 ) ; however , amitriptyline treatment result ed in significantly greater improvements ( p < .05 ) . P. ginseng reduced the number of tender points and improved patients ' quality of life ( using the Fibromyalgia Impact Question naire - FIQ ) ; however , there were no differences between groups . The beneficial effects experienced by patients for all parameters suggest a need for further studies to be performed on the tolerability and efficacy of this phytotherapic as a complementary therapy for fibromyalgia
While no clinical trial to date has specifically targeted fatigue , r and omized controlled trials , systematic review s , and meta-analyses indicate that treatment modalities studied in the context of other fibromyalgia symptoms could also improve fatigue .
Fatigue is a disabling , multifaceted symptom that is highly prevalent and stubbornly persistent .
Although fatigue is a frequent complaint among patients with fibromyalgia , it has not received the same attention as pain .
Reasons for this include lack of st and ardized nomenclature to communicate about fatigue , lack of evidence -based guidelines for fatigue assessment , and a deficiency in effective treatment strategies .
Fatigue does not occur in isolation ; rather , it is present concurrently in varying severity with other fibromyalgia symptoms such as chronic widespread pain , unrefreshing sleep , anxiety , depression , cognitive difficulties , and so on .
Survey-based and preliminary mechanistic studies indicate that multiple symptoms feed into fatigue and it may be associated with a variety of physiological mechanisms .