It was concluded that sesame consumption can significantly reduce blood TAG levels but there is insufficient evidence to support its hypocholesterolaemic effects .
Increased plasma lipid profiles are among the most important risk factors of CHD and stroke .
Sesame contains considerable amounts of vitamin E , MUFA , fibre and lignans , which are thought to be associated with its plasma lipid-lowering properties .
Ardeh (Sesamum indicum) could improve serum triglycerides and atherogenic lipid parameters in type 2 diabetic patients: a randomized clinical trial.
BACKGROUND Data suggest that sesame seeds have properties beneficial to modulating lipid disorders and decreasing cardiovascular disease ( CVD ) risk factors . The aim of this study was to investigate the effects of Ardeh , paste of ground unhulled sesame seeds , on lipid profiles and atherogenic lipid parameters . METHODS This r and omized clinical trial included 41 patients with type 2 diabetes , who were r and omly assigned to one of the two groups : group A ( Ardeh 28 g/d , n = 21 ) and group B ( control , n = 20 ) . After an initial two-week washout period , the patients in group A , replaced a part of their usual breakfast with two tablespoon ( tbsp ) ( ~ 28 g ) Ardeh , while group B patients continued the usual breakfast meal for six weeks ; energy content of both breakfast meals was maintained in the same range . Anthropometric measures , blood pressure , serum levels of total cholesterol ( TC ) , triglycerides ( TG ) , LDL-C , HDL-C , and atherogenic index of plasma ( AIP ; log TG/HDL-C ) , TC/HDL-C ratio , and LDL/HDL-C ratio were determined at baseline and six weeks later . RESULTS After six weeks , there were significant decreases in serum TG ( 15.3 mg/dL ) and AIP ( 39 % ) in group A. Moreover , slight decreases in serum TC , LDL-C , and other atherogenic lipid parameters and a mild increase in HDL-C also were observed during Ardeh supplementation . Anthropometric measures and blood pressure were unchanged during the study period in both groups . CONCLUSION Ardeh could have favorable effects in decreasing CVD risk factors in type 2 diabetics
It was concluded that sesame consumption can significantly reduce blood TAG levels but there is insufficient evidence to support its hypocholesterolaemic effects .
Increased plasma lipid profiles are among the most important risk factors of CHD and stroke .
Sesame contains considerable amounts of vitamin E , MUFA , fibre and lignans , which are thought to be associated with its plasma lipid-lowering properties .