Although this study did not consider placebo effect and has high IPSS baseline scores , this study clarifies that low-dose tamsulosin has generally positive effect and safety in treatment of LUTS and could be a suitable option as an initial treatment , especially for patients with low body mass index , as is typical of Asian people
PURPOSE In Asian countries , low-dose tamsulosin ( 0.2 mg ) is used widely but this dose has been less popular than 0.4 mg tamsulosin or other types of alpha blockers .
The aim of this study was to investigate the efficacy and safety of low-dose tamsulosin by systematic review and meta- analysis .
Recovery of abnormal ejaculation by intermittent tamsulosin treatment.
PURPOSE We assessed the impact of intermittent tamsulosin treatment on  abnormal ejaculation . MATERIAL S AND METHODS This prospect i ve study was performed between January 2001 and December 2004 . It included 405 patients who were at least 50 years old with lower urinary tract symptoms . This study was divided into 2 phases . In phase 1 patients received a 0.4 mg tamsulosin capsule daily after breakfast for at least 3 months . The second phase of this study was performed in the 30 patients with abnormal ejaculation . In this phase these patients received 0.4 mg tamsulosin once daily every other day . Patients were assessed at study entry and at study week 6 . RESULTS Abnormal ejaculation was reported as retro grade ejaculation by 18 patients , as decreased volume by 7 and as absent ejaculate by 5 . Ejaculatory function recovered during intermittent tamsulosin treatment in 12 patients with retro grade ejaculation and in 7 with decreased volume or absent ejaculate . As a result , 19 of 30 patients ( 63.3 % ) with abnormal ejaculation recovered . A significant improvement in retro grade ejaculation was found after intermittent tamsulosin treatment ( p = 0.02 ) . Although there were improvements in decreased volume or absent ejaculate at week 6 of intermittent treatment , these differences were not statistically significant ( p = 0.42 and 0.61 , respectively ) . CONCLUSIONS The results of the current study , which to our knowledge is the first report of the effect of intermittent tamsulosin treatment on abnormal ejaculation , show that this treatment modality is well tolerated and provides comparable improvements for abnormal ejaculation
Although this study did not consider placebo effect and has high IPSS baseline scores , this study clarifies that low-dose tamsulosin has generally positive effect and safety in treatment of LUTS and could be a suitable option as an initial treatment , especially for patients with low body mass index , as is typical of Asian people
PURPOSE In Asian countries , low-dose tamsulosin ( 0.2 mg ) is used widely but this dose has been less popular than 0.4 mg tamsulosin or other types of alpha blockers .
The aim of this study was to investigate the efficacy and safety of low-dose tamsulosin by systematic review and meta- analysis .