There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Circulating Adiponectin in Preterm Infants Fed Long-Chain Polyunsaturated Fatty Acids (LCPUFA)-Supplemented Formula—A Randomized Controlled Study
Adiponectin has potent insulin-sensitizing effects , improves lipid metabolism , and potentially protects against the development of metabolic syndrome . Thus , increasing adiponectin levels in preterm infants at risk for developing metabolic syndrome may be of special interest . The aim of this study was to examine the effects of dietary long-chain polyunsaturated fatty acids ( LCPUFA ) on serum adiponectin and lipid concentrations in preterm infants . Adiponectin and lipid levels of 60 healthy preterm infants [ gestational age 32.7 ( 1.9 ) wk ] r and omly assigned to be fed either 1 ) a formula containing LCPUFA [ arachidonic and docosahexanoic ] ( + LCPUFA group ) or 2 ) the same formula without LCPUFA ( −LCPUFA/control group ) , were determined at mean ( SD ) 33.8 ( 11.7 ) d. Adiponectin and HDL-C concentrations were significantly higher in the + LCPUFA group than in controls ( p = 0.002 and p = 0.01 , respectively ) ; whereas , triglyceride levels were lower ( p = 0.06 ) . Adiponectin correlated positively with HDL-C levels and negatively with triglyceride levels in the + LCPUFA group but not in the controls . In conclusion , circulating adiponectin concentrations were higher in preterm infants fed a formula containing LCPUFA than infants fed an LCPUFA-free formula and they correlated with lipidemic profile
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .