The Camino Verde trial of community mobilisation for control of dengue reported a significant impact on entomological indices of the Aedes aegypti vector , and on serological dengue virus infection and self-reported dengue cases .
One reason for doing r and omised controlled trials ( RCTs ) is that experiments can be convincing .
Early epidemiological experimenters , such as Jenner and the smallpox vaccine and Snow and his famous Broad Street pump h and le , already knew the answer they were demonstrating ; they used the experiments as knowledge translation devices to convince others .
More sophisticated modern experiments include cluster r and omised controlled trials ( C RCTs ) for experiments in the public health setting .
Those who are convinced by a trial and want to act , need to know how the trial relates to their own context , what contributed to success , and what might make it even more effective .
The Camino Verde intervention in Nicaragua, 2004–2012
Camino Verde ( the Green Way ) is an evidence -based community mobilisation tool for prevention of dengue and other mosquito-borne viral diseases . Its effectiveness was demonstrated in a cluster-r and omised controlled trial conducted in 2010–2013 in Nicaragua and Mexico . The Nicaraguan arm of the trial was preceded , from 2004 to 2008 , by a feasibility study that provided valuable lessons and trained facilitators for the trial itself . Here , guided by the Template for Intervention Description and Replication ( TIDieR ) , we describe the  Camino Verde intervention in Nicaragua , presenting its rationale , its time and location , activities , material s used , the main actors , modes of delivery , how it was tailored to encourage community engagement , modifications made from the feasibility study to the trial itself , and how fidelity to the process originally design ed was maintained . We also present information on costs and discuss the place of this study within the literature on implementation science . Trial registration IS RCT N27581154
The Camino Verde trial of community mobilisation for control of dengue reported a significant impact on entomological indices of the Aedes aegypti vector , and on serological dengue virus infection and self-reported dengue cases .
One reason for doing r and omised controlled trials ( RCTs ) is that experiments can be convincing .
Early epidemiological experimenters , such as Jenner and the smallpox vaccine and Snow and his famous Broad Street pump h and le , already knew the answer they were demonstrating ; they used the experiments as knowledge translation devices to convince others .
More sophisticated modern experiments include cluster r and omised controlled trials ( C RCTs ) for experiments in the public health setting .
Those who are convinced by a trial and want to act , need to know how the trial relates to their own context , what contributed to success , and what might make it even more effective .