There is no evidence of effectiveness in the alleviation of  menopausal symptoms with the use of phytoestrogen treatments
BACKGROUND Vasomotor symptoms , such as hot flushes and night sweats , are very common during the menopausal transition .
Hormone replacement therapy has traditionally been used as a very effective treatment but concerns over increased risks of some chronic diseases have markedly increased the interest of women in alternatives .
Some of the most popular of these are treatments based on foods or supplements enriched with phytoestrogens , plant-derived chemicals that have oestrogenic action .
OBJECTIVES To assess the efficacy , safety and acceptability of foods and supplements based on high levels of phytoestrogens for reducing hot flushes and night sweats in postmenopausal women .
Effects of a red clover extract (MF11RCE) on endometrium and sex hormones in postmenopausal women.
OBJECTIVE To evaluate the effects of a non-prescription red clover extract ( MF11 RCE , Melbrosin International , Vienna , Austria ) on selected sex hormones and endometrium in postmenopausal women . PATIENTS AND METHODS One-hundred and nine postmenopausal women with an age > or = 40 years were r and omly assigned to one of two groups either two capsules of MF11RCE ( 80 mg isoflavone ) per day for a 90 day period , or placebo of equal design . After a 7 day washout period , medication was crossed-over for another 90 days . RESULTS Combined evaluation demonstrated that supplementation with MF11RCE ( verum ) , in contrast to placebo , significantly increased plasma testosterone levels and decreased endometrial thickness . CONCLUSION MF11RCE exerts a moderate effect on testosterone levels in postmenopausal women , while estradiol levels remained unchanged . The observed reduction of endometrial thickness provides further support for a safe role for isoflavones in terms of endometrial hyperplasia
There is no evidence of effectiveness in the alleviation of  menopausal symptoms with the use of phytoestrogen treatments
BACKGROUND Vasomotor symptoms , such as hot flushes and night sweats , are very common during the menopausal transition .
Hormone replacement therapy has traditionally been used as a very effective treatment but concerns over increased risks of some chronic diseases have markedly increased the interest of women in alternatives .
Some of the most popular of these are treatments based on foods or supplements enriched with phytoestrogens , plant-derived chemicals that have oestrogenic action .
OBJECTIVES To assess the efficacy , safety and acceptability of foods and supplements based on high levels of phytoestrogens for reducing hot flushes and night sweats in postmenopausal women .