Therefore , vitamin A supplementation alone may reduce the risk of anemia , by improving hemoglobin and ferritin levels in individuals with low serum retinol levels
ABSTRACT Anemia is a worldwide public health problem that can be related to many causes , including vitamin A deficiency .
The aim of this study was to assess and estimate the effect of vitamin A supplementation ( VAS ) on iron status biomarkers and anemia in humans .
Effect of single-dose albendazole and vitamin A supplementation on the iron status of pre-school children in Sichuan, China.
The aim of this study was to explore the effect of single-dose albendazole and vitamin A intervention on the anaemic status and Fe metabolism of pre-school children . This study was a r and omised , placebo-controlled and double-blinded intervention trial . All eligible anaemic pre-school children were r and omly divided into three groups : group 1 received no intervention , which served as the control group , group 2 received 400 mg single-dose albendazole administration and group 3 received a 60000 μg vitamin A capsule combined with 400 mg single-dose albendazole at the beginning of the study . The follow-up period was for 6 months . Anthropometry and biochemical index about Fe metabolism were measured before and after intervention . A total of 209 pre-school anaemic children were r and omly divided into three intervention groups ( sixty-four , sixty-two and sixty for groups 1 , 2 and 3 , respectively ) . The mean age of the children in the study was 4·4 ( sd 0·7 ) years and 50·5 % of the children were female ( 94/186 ) . After a follow-up period of 6 months , the levels of serum retinol , ferritin , transferrin receptor-ferritin index and body total Fe content of children in group 3 were significantly higher compared with children in groups 1 and 2 ( P<0·05 ) . Moreover , the proportion of vitamin A deficiency , marginal vitamin A deficiency and Fe deficiency among children in group 3 were markedly lower compared with children in groups 1 and 2 ( P<0·05 ) . Albendazole plus vitamin A administration showed more efficacy on the improvement of serum retinol and Fe metabolic status
Therefore , vitamin A supplementation alone may reduce the risk of anemia , by improving hemoglobin and ferritin levels in individuals with low serum retinol levels
ABSTRACT Anemia is a worldwide public health problem that can be related to many causes , including vitamin A deficiency .
The aim of this study was to assess and estimate the effect of vitamin A supplementation ( VAS ) on iron status biomarkers and anemia in humans .