This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
Effects of Calcium Plus Vitamin D Supplementation on Anthropometric Measurements and Blood Pressure in Vitamin D Insufficient People with Type 2 Diabetes: A Randomized Controlled Clinical Trial
Background : Up to 75 % of the risk of type 2 diabetes is attributable to obesity . Therefore , finding a way to control obesity can be useful for management of diabetes . Objective : This study was performed to assess the effects of vitamin D3 and calcium supplementation on anthropometric measurements and blood pressure in vitamin D insufficient people with type 2 diabetes . Methods : One hundred eighteen patients with diabetes were enrolled in this r and omized placebo-controlled clinical trial . All subjects were r and omly assigned into 4 groups receiving ( 1 ) 50,000 IU/wk vitamin D3 plus ( equal to 7143 IU/d ) calcium placebo ; ( 2 ) 1000 mg/d calcium plus vitamin D3 placebo ; ( 3 ) 50,000 IU/wk vitamin D3 ( equal to 7143 IU/d ) plus 1000 mg/d calcium ; or ( 4 ) vitamin D3 placebo plus calcium placebo for 8 weeks . Anthropometric measurements and blood pressure were assessed at study baseline and after 8 weeks of intervention . Results : A greater reduction in body mass index was observed in calcium plus vitamin D group than other groups ( p = 0.03 ) . Comparison of changes in waist circumference among 4 groups revealed no significant difference in crude model ( p = 0.21 ) and when the effect of confounders was taken into account ( p = 0.08 ) . Calcium supplementation result ed in a significant reduction in hip circumference compared to other groups ( p < 0.001 ) . Systolic blood pressure significantly decreased in the calcium plus vitamin D group compared to placebo ( −7.3 ± 8.7 mmHg vs 0.5 ± 8.2 mmHg ; p = 0.001 ) . However , calcium and vitamin D supplementation had no significant effects on diastolic blood pressure . Conclusion : Calcium – vitamin D3 cosupplementation can have beneficial effect on body mass index ( BMI ) , hip circumference , and systolic blood pressure in vitamin D – insufficient type 2 diabetics
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .