Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
A randomized controlled trial of dietary fiber intake on serum lipids
Objective : Clinical trials have indicated that water-soluble fiber from oats reduces serum cholesterol among hypercholesterolemic patients on a low-fat diet . We examined the effect of dietary fiber intake on serum lipids among persons without hypercholesterolemia . Design : R and omized controlled trial . Setting and subjects : We recruited 110 participants who were aged 30–65 years and had a serum cholesterol level < 240 mg/dl from community . Intervention : Study participants were r and omly assigned to receive 8 g per day of water-soluble fiber from oat bran or a control intervention . Results : At baseline , the mean levels of serum cholesterol and other measured variables were comparable between the high-fiber and control groups . Over the 3-month intervention , mean changes ( 95 % confidence interval ( CI ) ) in total , HDL- , and LDL-cholesterol were −2.42 mg/dl ( −8.90 to 4.05 mg/dl ; P=0.46 ) , −0.24 mg/dl ( −2.19 to 1.71 mg/dl ; P=0.81 ) , and −1.96 mg/dl ( −7.32 to 3.40 mg/dl ; P=0.47 ) in the fiber group and −0.02 mg/dl ( −5.29 to 5.26 mg/dl ; P=0.99 ) , 1.42 mg/dl ( −0.74 to 3.59 mg/dl ; P=0.19 ) , and −0.64 mg/dl ( −5.30 to 4.03 mg/dl ; P=0.79 ) in the control group , respectively . The net changes ( 95 % confidence interval ) in total , HDL- , and LDL-cholesterol were −2.40 mg/dl ( −10.6 to 5.81 mg/dl ; P=0.56 ) , −1.66 mg/dl ( −4.55 to 1.22 mg/dl ; P=0.26 ) and −1.33 mg/dl ( −8.33 to 5.68 mg/dl ; P=0.71 ) , respectively . Conclusions : Our study does not support the hypothesis that water-soluble fiber intake from oat bran  reduces total and LDL-cholesterol in study participants with a normal serum cholesterol level
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .