The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride .
No difference was found when RM-GIC was compared with fluoride-containing composite resin .
RM-GIC showed efficacy in reducing demineralization .
UNLABELLED The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers ( RM-GIC ) , in comparison to fluoride-containing composite resin and composite resin without fluoride , are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge .
Evidence favoring the use of anticoagulants in the hospital phase of acute myocardial infarction.
Since the last comprehensive review of anticoagulation in acute myocardial infa rct ion four additional r and omized control trials have been reported . The overwhelming majority of all trials favored anticoagulation .  Rates of thromboembolism were higher in the control , and hemorrhagic complications in the anticoagulated group . Pooling of all r and omized control trials gives mean case fatality rates of 19.6 % for the control and 15.4 % for the anticoagulated group , a relative reduction of 21 % ( P less than 0.05 or less than 0.001 , depending on the analytic method ) . Five of six r and omized control trials reported " no effect " because the difference favoring anticoagulation was not statistically significant . However , sample sizes in these " negative " papers were too small to protect against missing a 21 % reduction in true case fatality rate due to anticoagulation ( beta greater than 0.10 ) . All patients who present no specific contraindication should receive  anticoagulants  during hospitalization for infa rct ion
The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride .
No difference was found when RM-GIC was compared with fluoride-containing composite resin .
RM-GIC showed efficacy in reducing demineralization .
UNLABELLED The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers ( RM-GIC ) , in comparison to fluoride-containing composite resin and composite resin without fluoride , are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge .