Overall , the current literature supports clearly the dose-response relationship between physical activity and the seven chronic conditions identified .
Moreover , higher levels of physical activity reduce the risk for premature all-cause mortality .
The current Canadian guidelines appear to be appropriate to reduce the risk for the seven chronic conditions identified above and all-cause mortality
This systematic review examines critically the scientific basis for Canada 's Physical Activity Guide for Healthy Active Living for adults .
Particular reference is given to the dose-response relationship between physical activity and premature all-cause mortality and seven chronic diseases ( cardiovascular disease , stroke , hypertension , colon cancer , breast cancer , type 2 diabetes ( diabetes mellitus ) and osteoporosis ) .
The strength of the relationship between physical activity and specific health outcomes is evaluated critically .
Physical Activity and Coronary Event Incidence in Northern Ireland and France: The Prospective Epidemiological Study of Myocardial Infarction (PRIME)
Background —The influence of physical activity on the incidence of angina pectoris and hard coronary events ( myocardial infa rct ion and coronary deaths ) was examined in Northern Irel and and France at contrasting risk for coronary heart disease ( CHD ) and with different physical activity patterns . Methods and Results — Participants of the Prospect i ve Epidemiological Study of Myocardial Infa rct ion ( PRIME ) ( n=9758 ; age , 50 to 59 years ) , free of CHD at baseline , were followed up for 5 years : 167 hard CHD and 154 angina events were recorded .  Net energy expenditure ( EE ) as the result of physical activity was assessed by means of the MONICA Optional Study of Physical Activity Question naire ( MOSPA-Q ) .  Leisure-time physical activity EE was calculated ; subjects were also categorized as to whether they performed high-intensity leisure-time activities or walked or cycled to work . After multivariate adjustment , leisure-time physical activity EE was associated with a lower risk of hard CHD events ( P < 0.04 ) , whereas walking or cycling to work was not independently related to hard CHD events . No interaction by country was found . The beneficial effect of leisure-time physical activity  was also present among subjects who did not report high-intensity activities ( P < 0.04 ) , with similar results in France and Northern Irel and . In contrast , an increasing level of leisure-time physical activity  was associated with a higher risk of angina in both countries . Conclusions —These data indicate a beneficial effect of leisure-time physical activity EE on hard CHD incidence in middle-aged men , which could partly explain the unfavorable rate of CHD in Northern Irel and . The higher level of leisure-time activities in France could , in part , explain its lower rate of CHD
Overall , the current literature supports clearly the dose-response relationship between physical activity and the seven chronic conditions identified .
Moreover , higher levels of physical activity reduce the risk for premature all-cause mortality .
The current Canadian guidelines appear to be appropriate to reduce the risk for the seven chronic conditions identified above and all-cause mortality
This systematic review examines critically the scientific basis for Canada 's Physical Activity Guide for Healthy Active Living for adults .
Particular reference is given to the dose-response relationship between physical activity and premature all-cause mortality and seven chronic diseases ( cardiovascular disease , stroke , hypertension , colon cancer , breast cancer , type 2 diabetes ( diabetes mellitus ) and osteoporosis ) .
The strength of the relationship between physical activity and specific health outcomes is evaluated critically .