There is some evidence that haloperidol is an effective treatment for  acute mania .
From the limited data available , there was no difference in overall efficacy of treatment between haloperidol and olanzapine or risperidone .
Some evidence suggests that haloperidol could be less effective than aripiprazole .
BACKGROUND The main objectives in treating mania are to control dangerous behaviour , reduce suicide , produce appropriate acute sedation and shorten the episode of mood disturbance .
Among different drugs , haloperidol has for many years been used in treating psychotic patients , but it has a troublesome side effect profile .
OBJECTIVES To assess the effects of haloperidol for the treatment of mania in comparison with placebo or other active drugs , either as monotherapy or add-on treatment .
Carbamazepine compared to haloperidol in acute mania.
In a double-blind , between-patient clinical trial carbamazepine ( CBZ ) ( n = 8) was compared to haloperidol ( HP ) ( n = 9 ) in patients presenting with mania ( DSM III ) . Seven patients on HP and 2 on CBZ  failed to complete 4 weeks treatment . In 4 of the  HP  group this was because of extrapyramidal side-effects ( EPS ) . Two patients on CBZ and 2 on HP were withdrawn because of lack of efficacy . Statistically significant clinical improvement was seen in both groups within the first 2 weeks of treatment with HP acting more quickly . In addition to EPS which occurred in HP patients , drowsiness was experienced in 4 on CBZ and 3 on HP , and gastrointestinal symptoms in 3 on CBZ . No serious haematological changes , nor abnormalities in clinical chemistry occurred in either group . We conclude that CBZ appears to be a potentially useful drug in the treatment of acute mania
There is some evidence that haloperidol is an effective treatment for  acute mania .
From the limited data available , there was no difference in overall efficacy of treatment between haloperidol and olanzapine or risperidone .
Some evidence suggests that haloperidol could be less effective than aripiprazole .
BACKGROUND The main objectives in treating mania are to control dangerous behaviour , reduce suicide , produce appropriate acute sedation and shorten the episode of mood disturbance .
Among different drugs , haloperidol has for many years been used in treating psychotic patients , but it has a troublesome side effect profile .
OBJECTIVES To assess the effects of haloperidol for the treatment of mania in comparison with placebo or other active drugs , either as monotherapy or add-on treatment .