No significant difference was found between other treatments .
Conclusion Compared with antimuscarinic drugs , PTENS was associated with significant better efficacy considering MVV , but more constipation events in de novo OAB children .
Antimuscarinic drugs showed remarkably better efficacy considering MVV and comparable safety profile compared with urotherapy .
Objective To compare these managements focusing on the efficacy and safety to treat overactive bladder ( OAB ) in children through network meta- analysis ( NMA ) .
Transcutaneous electrical nerve stimulation in children with overactive bladder: a randomized clinical trial.
PURPOSE We evaluated the effectiveness of parasacral transcutaneous electrical nerve stimulation to treat overactive bladder in children . We design ed a prospect i ve r and omized trial with sham control for this evaluation . MATERIAL S AND METHODS We prospect ively r and omized 25 girls and 12 boys with an average age of 7.6 years ( range 4 to 12 ) into the test ( active treatment ) or sham ( superficial scapular electrical stimulation ) group . A total of 20 sessions , 20 minutes each ( 10 Hz ) were performed 3 times weekly . The criteria used to evaluate the rate of success were 1 ) self-reported cure , or significant , mild or no improvement ; 2 ) visual analogue scale ( level of success 0 to 10 ) ; 3 ) percent improvement ; 4 ) modified Toronto score ; and 5 ) maximum voided volume , average voided volume and number of voids daily based on bladder diary entries . After completion of the 20 sessions controls who were not cured underwent active treatment . RESULTS A total of 21 patients in the test group and 16 in the sham group underwent treatment . Among the active treatment group 61.9 % of parents reported cure . In the sham group no parent reported cure ( p < 0.001 ) . Regarding visual analogue scale a score of 10 was indicated by 13 parents in the test group , while 1 parent in the sham group indicated a score of 9 ( p = 0.002 ) . Additionally 100 % improvement was reported by 12 parents in the test group and no parent in the sham group . Toronto score improved significantly in the test group ( p < 0.001 ) and sham group ( p = 0.008 ) . However , the score was reduced more significantly in the test group compared to the sham group ( p = 0.011 ) . In the test group average and maximum voided volumes showed a statistically significant increase and the number of voids daily decreased . After superficial scapular electrical stimulation 13 of the 16 patients who underwent parasacral transcutaneous electrical nerve stimulation were cured . CONCLUSIONS This is the first known r and omized clinical trial to demonstrate that parasacral transcutaneous electrical nerve stimulation is effective in the treatment of children with overactive bladder
No significant difference was found between other treatments .
Conclusion Compared with antimuscarinic drugs , PTENS was associated with significant better efficacy considering MVV , but more constipation events in de novo OAB children .
Antimuscarinic drugs showed remarkably better efficacy considering MVV and comparable safety profile compared with urotherapy .
Objective To compare these managements focusing on the efficacy and safety to treat overactive bladder ( OAB ) in children through network meta- analysis ( NMA ) .