Meta- analysis of BMI values at end of trial showed no statistically significant difference in BMI change by use of 25[OH]D supplementation .
Based on existing published trials , oral 25[OH]D supplementation does not significantly impact BMI change
The impact of 25-hydroxyvitamin D ( 25[OH]D ) supplementation on weight change remains controversial .
The objective of this study was to summarize the effects of 25[OH]D supplementation ( cholecalciferol or ergocalciferol ) on BMI change through a meta- analysis of published clinical trials .
Pattern of 25-hydroxy vitamin D response at short (2 month) and long (1 year) interval after 8 weeks of oral supplementation with cholecalciferol in Asian Indians with chronic hypovitaminosis D.
Hypovitaminosis D is common in Asian Indians . Physicians often prescribe 1500 mug ( 60 000 IU ) cholecalciferol per week for 8 weeks for vitamin D deficiency in India . Its efficacy to increase serum 25-hydroxy vitamin D ( 25(OH)D ) over short ( 2 months ) and long ( 1 year ) term is not known . We supplemented a group of twenty-eight apparently healthy Asian Indians detected to have low serum 25(OH)D ( mean 13.5 ( sd 3.0 ) nmol/l ) on screening during January-March 2005 .  Serum parathyroid hormone ( PTH ) level was supranormal in 30 % of them . Oral supplementation included 1500 mug cholecalciferol per week and 1 g elemental Ca daily for 8 weeks . Serum 25(OH)D , total Ca , inorganic P and intact ( i ) PTH were reassessed in twenty-three subjects ( twelve females and eleven males ) who had follow up at both 8 weeks and 1 year . At 8 weeks the mean 25(OH)D levels increased to 82.4 ( sd 20.7 ) nmol/l and serum PTH normalized in all . Twenty-two of the twenty-three subjects had 25(OH)D levels>49.9 nmol/l . At 1 year , though the mean 25(OH)D level of 24.7 ( sd 10.9 ) nmol/l was significantly higher than the baseline , all subjects were 25(OH)D deficient . Five subjects with supranormal iPTH at baseline showed recurrence of biochemical hyperparathyroidism . Thus , with 8 weeks of cholecalciferol supplementation in Asian Indians with chronic hypovitaminosis D , mean serum 25(OH)D levels would be normalized and serum PTH value would be reduced to half . However , such quick supplementation would not maintain their 25(OH)D levels in the sufficient range for 1 year . For sustained improvement in 25(OH)D levels  vitamin D supplementation has to be ongoing after the initial cholecalciferol loading
Meta- analysis of BMI values at end of trial showed no statistically significant difference in BMI change by use of 25[OH]D supplementation .
Based on existing published trials , oral 25[OH]D supplementation does not significantly impact BMI change
The impact of 25-hydroxyvitamin D ( 25[OH]D ) supplementation on weight change remains controversial .
The objective of this study was to summarize the effects of 25[OH]D supplementation ( cholecalciferol or ergocalciferol ) on BMI change through a meta- analysis of published clinical trials .