Zn supplementation was associated with increased fat-free mass among stunted children .
Due to the use of anthropometry when determining body composition , a majority of the studies could not accurately address whether alterations in the fat and /or fat-free mass components of the body were responsible for the observed changes in body composition .
The effect of Zn supplementation on body composition is not consistent but may modify fat-free mass among children with pre-existing growth failure
OBJECTIVE To provide a comprehensive synthesis of the effects of Zn supplementation on childhood body composition and adiposity-related hormone levels .
Zinc supplementation in infants with asymmetric intra uterine growth retardation; effect on growth, nutritional status and leptin secretion.
OBJECTIVES To analyse the effect of zinc supplementation in growth and nutritional status of a homogeneous group of newborns with intra uterine growth retardation and asymmetric growth . The effect of changes of zinc status on growth and leptin serum concentrations was also analysed . POPULATION AND METHODS A double blind , r and omised clinical trial was design ed in order to detect differences in growth between zinc and placebo groups during the first 6 months of life . 31 infants were included either to the zinc group ( n = 14 ) ( 38.8+/-1.4 weeks GA , 2,171+/-253 g body weight ) or the placebo group ( n = 17 ) ( 38.9+/-1.1 weeks GA , 2,249+/-220 g body weight ) . The zinc group received a supplement of 3 mg elemental zinc per day ( as zinc sulphate ) . RESULTS There were not significant differences between groups for anthropometric measurements through the study period . We found a significant effect of the study group , in hair zinc concentrations , but not in serum zinc concentrations ; post-hoc comparisons for hair zinc revealed that there were significant differences between groups at 1 , 2 , and 6 months of age . Changes in serum and hair zinc concentrations from baseline to 6 months , showed significant correlations with changes in weight/age and length/age z-scores , in the supplement group . Changes in leptin serum concentrations during follow-up , showed significant correlations with changes in sum of 4 skinfolds and weight/age z-score , in the placebo group . Changes in hair zinc concentration through the study period showed significant correlations with changes in leptin serum concentrations from baseline to 6 months of follow-up . CONCLUSIONS In a homogeneous group of intra uterine growth retardation infants with asymmetric growth , 3 mg/day zinc supplementation do not show significant improvements in weight and length growth . Changes in zinc status were related with changes in weight and length during the first 6 months of life . Changes in leptin serum concentrations were related with changes in the anthropometric indices of body fat accretion
Zn supplementation was associated with increased fat-free mass among stunted children .
Due to the use of anthropometry when determining body composition , a majority of the studies could not accurately address whether alterations in the fat and /or fat-free mass components of the body were responsible for the observed changes in body composition .
The effect of Zn supplementation on body composition is not consistent but may modify fat-free mass among children with pre-existing growth failure
OBJECTIVE To provide a comprehensive synthesis of the effects of Zn supplementation on childhood body composition and adiposity-related hormone levels .