The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .
Intraoperative conditions and quality of postoperative analgesia after adding dexmedetomidine to epidural bupivacaine and fentanyl in elective cesarean section using combined spinal-epidural anesthesia
This study was design ed to evaluate the effect of adding dexmedetomidine to regular mixture of epidural drugs for pregnant women undergoing elective cesarean section with special emphasis on their sedative properties , ability to improve quality of intraoperative , postoperative analgesia , and neonatal outcome . Material s and Methods : Fifty women of ASA physical status I or II at term pregnancy were enrolled r and omly to receive plain bupivacaine plus fentanyl ( BF Group ) or plain bupivacaine plus mixture of fentanyl and dexmedetomidine ( DBF Group ) . Incidence of hypotension , bradycardia , Apgar scores , intraoperative pain assessment , onset of postoperative pain , sedation scores , and side effects were recorded . Results : No difference in the times taken for block to reach T4 sensory level , to reach the highest level of sensory block , and interval between first neuraxial injection and onset of surgery between the groups was noted . Onset of postoperative pain was significantly delayed in the DBF group ( P = 0.001 ) , the need for supplementary fentanyl was significantly less in DBF group ( P = 0.03 ) , no significant difference was noted between both groups regarding neonatal Apgar scores as well as the incidence of hypotension , bradycardia , nausea , vomiting , and duration of motor blockade . DBF group had significantly less incidence of shivering ( P = 0.03 ) . Conclusion : Adding dexmedetomidine to regular mixture of epidural anesthetics in women undergoing elective cesarean section improved intraoperative conditions and quality of postoperative analgesia without maternal or neonatal significant side effects
The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .