In conclusion , this review supports the hypothesis that hypovitaminosis D is associated with adverse outcomes after diverse surgical procedures .
The importance of vitamin D for musculoskeletal health has long been recognized , and awareness of significant extra-skeletal effects in health and disease is rapidly emerging .
Although it has been possible for many decades to quantify serum markers of vitamin D deficiency , and to correct deficiency at low cost and with high safety , the influence of vitamin D status on post-surgical outcomes has only recently been identified as a research topic of interest .
To the present , these data have not been the subject matter of formal review .
Accordingly , we conducted a systematic review to assess the association between perioperative vitamin D status and outcomes after surgery .
Low vitamin D status does not adversely affect short-term functional outcome after total hip arthroplasty.
We prospect ively measured functional performances ( Western Ontario and McMaster Universities Osteoarthritis Index , Short Form-36 , 2-minute walk test , and timed get-up- and -go test ) of patients who underwent total hip arthroplasty ( THA )  and had serum vitamin D levels tested during the preoperative evaluation . Of 219 patients , 102 ( 46.6 % ) had low vitamin D levels ( 25-hydroxyvitamin D<30 ng/mL ) . Low vitamin D status did not adversely affect short-term function at 6 weeks after THA . In addition , there was no association between serum vitamin D levels and the within-patient changes of scores of each outcome measurement . Because this 6-week period is generally adequate to correct vitamin D deficiency , orthopedic surgeons can safely perform THA without delay . Nevertheless , because vitamin D deficiency impairs bone quality , patients with low vitamin D levels should be treated once identified
In conclusion , this review supports the hypothesis that hypovitaminosis D is associated with adverse outcomes after diverse surgical procedures .
The importance of vitamin D for musculoskeletal health has long been recognized , and awareness of significant extra-skeletal effects in health and disease is rapidly emerging .
Although it has been possible for many decades to quantify serum markers of vitamin D deficiency , and to correct deficiency at low cost and with high safety , the influence of vitamin D status on post-surgical outcomes has only recently been identified as a research topic of interest .
To the present , these data have not been the subject matter of formal review .
Accordingly , we conducted a systematic review to assess the association between perioperative vitamin D status and outcomes after surgery .