Moreover , subgroup analyses suggested that the effects of glycemic control were significantly influenced by the sex of the subjects and the type and the method of intake of ITF .
Conclusions Our analyses confirmed that these four main glycemic indicators were significantly reduced by ITF supplementation , particularly in the prediabetes and T2DM population .
Evidence supports that reasonable administration of ITF supplementation may have potential clinical value as an adjuvant therapy for prediabetes and T2DM management .
Background Currently , many clinical trials have shown that inulin-type fructans ( ITF ) supplementation is associated with glycemic control ; nevertheless , the results are inconclusive .
The aim of this meta- analysis of r and omized controlled trials was to assess the effects of ITF supplementation on glycemic control .
Effects of Fructo-Oligosaccharide Supplementation on Constipation in Elderly Continuous Ambulatory Peritoneal Dialysis Patients
♦ Background : Fructo-oligosaccharides ( FOS ) exhibit soluble-fiber properties that beneficially affect bowel function and relieve constipation . The effects of FOS supplementation on constipation and biochemical parameters were examined in elderly continuous ambulatory peritoneal dialysis ( CAPD ) patients . ♦ Methods : This r and omized , double-blind , placebo-controlled , cross-over study was performed in elderly CAPD patients ( 5 males and 4 females ) with chronic constipation . All subjects were r and omly assigned to receive either 20 g FOS or placebo daily for 30 days . After a 14-day washout period , the patients were switched to the other substance for 1 more month . Before and after each treatment period , frequency of defecation , characteristics of feces , and colonic transit were evaluated . Biochemical parameters were also assessed . ♦ Results : Fructo-oligosaccharides significantly increased the frequency of defecation ( 10.5 ± 2.0 vs 6.2 ± 1.4 times per week , p < 0.005 ) and changed the feces ' appearance from type 1 ( nut-like ) to type 4 ( sausage – like ) . The colonic transit determined by geometric center ( GC ) was augmented after FOS supplementation ( 3.9 ± 0.3 vs 3.2 ± 0.4 , p < 0.05 ) . Fructo-oligosaccharides had no effects on biochemical parameters . Fructo-oligosaccharides caused mild discomforts which were well tolerated after dose adjustment . ♦ Conclusions : Fructo-oligosaccharide supplementation is effective , well tolerated , and can be an alternative to other laxatives in CAPD patients with constipation . Further studies are needed to better assess the biochemical effects of FOS in the chronic kidney disease population
Moreover , subgroup analyses suggested that the effects of glycemic control were significantly influenced by the sex of the subjects and the type and the method of intake of ITF .
Conclusions Our analyses confirmed that these four main glycemic indicators were significantly reduced by ITF supplementation , particularly in the prediabetes and T2DM population .
Evidence supports that reasonable administration of ITF supplementation may have potential clinical value as an adjuvant therapy for prediabetes and T2DM management .
Background Currently , many clinical trials have shown that inulin-type fructans ( ITF ) supplementation is associated with glycemic control ; nevertheless , the results are inconclusive .
The aim of this meta- analysis of r and omized controlled trials was to assess the effects of ITF supplementation on glycemic control .