The present review demonstrates that vitamin D supplementation result ed in small but nonsignificant improvements in muscle strength compared to control in postmenopausal women .
No significant effect was observed in mobility after vitamin D administration
BACKGROUND The results obtained from previous trials regarding the effects of vitamin D supplementation on muscle strength and mobility  in postmenopausal women have been inconsistent .
This systematic review and meta- analysis of r and omised controlled trials ( RCTs ) aim ed to investigate the effect of vitamin D supplementation on muscle strength and mobility in postmenopausal women .
Eldecalcitol improves muscle strength and dynamic balance in postmenopausal women with osteoporosis: an open-label randomized controlled study
The antifracture efficacy of vitamin D in osteoporosis is due to its direct action on bones and indirect extraskeletal effects to prevent falls . Eldecalcitol is an analog of active vitamin D3 that improves bone mineral density and reduces the risk of osteoporotic fractures . However , the effects of eldecalcitol on muscle strength and static and dynamic postural balance are unclear . In this open-label r and omized controlled study , we assessed the effects of eldecalcitol on muscle strength and static and dynamic postural balance in 50 postmenopausal women ( mean age 74 years ) with osteoporosis treated with bisphosphonate . Participants were r and omly divided into a bisphosphonate group ( alendronate at 35 mg/week ; n = 25 ) or an eldecalcitol group ( eldecalcitol at 0.75 μg/day and alendronate at 35 mg/week ; n = 25 ) and were followed up for 6 months . Trunk muscle strength , including back extensor strength and iliopsoas muscle strength , was measured . Static st and ing balance was evaluated and the one leg st and ing test was performed to assess static postural balance . Dynamic sitting balance was evaluated and the 10-m walk test , functional reach test , and timed up and go test were performed to assess dynamic postural balance . At 6 months , there were no significant changes in any measure of muscle strength or balance in the bisphosphonate group , whereas eldecalcitol significantly increased back extensor strength ( p = 0.012 ) and iliopsoas muscle strength ( p = 0.035 ) . Eldecalcitol also significantly improved findings on the timed up and go test ( p = 0.001 ) and dynamic sitting balance ( p = 0.015 ) at 6 months . These results with eldecalcitol may have an impact on prevention of falls
The present review demonstrates that vitamin D supplementation result ed in small but nonsignificant improvements in muscle strength compared to control in postmenopausal women .
No significant effect was observed in mobility after vitamin D administration
BACKGROUND The results obtained from previous trials regarding the effects of vitamin D supplementation on muscle strength and mobility  in postmenopausal women have been inconsistent .
This systematic review and meta- analysis of r and omised controlled trials ( RCTs ) aim ed to investigate the effect of vitamin D supplementation on muscle strength and mobility in postmenopausal women .