INTERPRETATION There was a clinical ly relevant association between early migration of TKPs and late revision for loosening .
PURPOSE We performed two parallel systematic review s and meta-analyses to determine the association between early migration of tibial components and late aseptic revision .
Five-year results of the Sigma total knee arthroplasty.
The DePuy Sigma total knee arthroplasty ( TKA ) was introduced in 1997 as a modification of the Press Fit Condylar Knee ( PFC ) TKA and has been used extensively in the United Kingdom and worldwide . It is the most commonly used TKA in Engl and and Wales , where it accounts for 36 % of all primary TKA . The PFC was well established , with reported 10-year survival rates of 93 - 97 % , but this study reports the first 5-year clinical and radiographic follow-up data for the Sigma TKA . Over a 10-month period , 212 Sigma TKAs were performed in 180 patients . Patients were seen at a specialist nurse-led clinic 7 to 10 days before admission and at 6 months , 18 months , 3 years and 5 years after surgery . Data were recorded prospect ively at each visit . Radiographs were obtained at the 5-year follow-up appointment . Of 212 knees , 178 ( 151 patients ) were alive at 5 years . Three were lost to follow up . Six knees ( 3.0 % ) were revised , five for infection and one underwent change of polyethylene insert at 4.9 years . Five-year survival with an endpoint of revision for any reason was 97.0 % ; with an endpoint of revision for aseptic failure it was 99.5 % . The median American Knee Society knee rating score was 93 out of 100 at 5 years compared with 25 out of 100 at admission . Of 147 radiographs , none showed radiographic loosening of either component . Seventeen ( 11.6 % ) showed radiolucent lines . Twenty-eight ( 19.0 % ) had alignment outside the range of 7+/-3 degrees valgus . These results suggest that the Sigma TKA gives acceptable clinical results after 5 years . Further follow-up studies are required to see if this performance is maintained in the long term
INTERPRETATION There was a clinical ly relevant association between early migration of TKPs and late revision for loosening .
PURPOSE We performed two parallel systematic review s and meta-analyses to determine the association between early migration of tibial components and late aseptic revision .