A Medline search of research on pharmacotherapy was undertaken , and a previous systematic review on the evidence -based pharmacotherapy of panic disorder was up date d. Selective serotonin reuptake inhibitors remain a first-line pharmacotherapy of panic disorder , with the serotonin noradrenaline reuptake inhibitor venlafaxine also an acceptable early option .
Temporary co-administration of benzodiazepines can be considered .
For patients not responding to first-line agents several pharmacotherapy options are available , but there is a notable paucity of data on the optimal choice
The evidence -based pharmacotherapy of panic disorder continues to evolve .
This paper review s data on first-line pharmacotherapy , evidence for maintenance treatment , and management options for treatment-refractory patients .
Prevalence of mental disorders and psychosocial impairments in adolescents and young adults.
BACKGROUND As part of a longitudinal study , prevalence findings of DSM-IV disorders are presented for a r and om sample of 3021 respondents aged 14 to 24 , with response rate 71 % . METHOD Assessment included various subtypes of disorders , subthreshold conditions and disorders that have only rarely been studied in other epidemiological surveys . The computer-assisted Munich-Composite International Diagnostic Interview ( M-CIDI ) was used to derive DSM-IV diagnoses . RESULTS Substance disorders were the most frequent ( lifetime 17.7 % ; 12-month 11.4 % ) , with abuse being considerably more frequent than dependence . Other mental disorders had a lifetime prevalence of 27.5 % ( 12-month , 17.5 % ) with depressive disorders ( 16.8 % ) being more frequent than anxiety disorders ( 14.4 % ) . Eating disorders ( 3.0 % ) and threshold somatoform disorders ( 1.2 % ) were rare disorders . Subthreshold anxiety and somatoform disorders , however , were more frequent than threshold disorders . Prevalence of disorders was equally high for males and females , although specific disorder prevalence varied significantly by gender . The co-occurrence of disorders ( co-morbidity ) was substantial and was significantly related to greater reductions in work productivity and increased rates of professional helpseeking behaviour . CONCLUSIONS Findings underline that mental disorders in young adults are frequent and impairing , limiting work and education ability and social interaction . Given the fact that adolescents and young adults are in a key phase of socialization in terms of professional career and interpersonal relationships , our findings indicate a considerable risk potential for an accumulation of complicating factors and future chronicity . This paper is the first report of this ongoing longitudinal study about early developmental conditions of mental disorders
A Medline search of research on pharmacotherapy was undertaken , and a previous systematic review on the evidence -based pharmacotherapy of panic disorder was up date d. Selective serotonin reuptake inhibitors remain a first-line pharmacotherapy of panic disorder , with the serotonin noradrenaline reuptake inhibitor venlafaxine also an acceptable early option .
Temporary co-administration of benzodiazepines can be considered .
For patients not responding to first-line agents several pharmacotherapy options are available , but there is a notable paucity of data on the optimal choice
The evidence -based pharmacotherapy of panic disorder continues to evolve .
This paper review s data on first-line pharmacotherapy , evidence for maintenance treatment , and management options for treatment-refractory patients .