There is not enough evidence to support one adhesive or bonding strategy over another for treatment of NCCLs .
CLINICAL SIGNIFICANCE Studies with low overall risk of bias demonstrated good clinical performance for adhesives with all four bonding strategies .
However , included studies showed wide variation between adhesives of the same category
OBJECTIVES To establish whether simplified adhesives ( self-etch ) are as clinical ly effective as conventional adhesives ( etch- and -rinse ) with multiple application steps for treatment of non-carious cervical lesions ( NCCLs ) .
NULL HYPOTHESIS there is no difference in the clinical effectiveness of the four different bonding strategies : Three-step etch- and -rinse ; Two-step etch- and -rinse ; Two-step self-etch ; One-step self-etch for treatment of NCCLs .
Correlation between microtensile bond strength data and clinical outcome of Class V restorations.
OBJECTIVE To determine if the results of  resin-dentin microtensile bond strength ( μTBS ) is correlated with the outcome parameters of clinical studies on non-retentive Class V restorations . METHODS  Resin-dentin μTBS data were obtained from one test center ; the in vitro tests were all performed by the same operator . The μTBS testing was performed 8 h after bonding and after 6 months of storing the specimens in water . Pre-test failures ( PTFs ) of specimens were included in the analysis , attributing them a value of 1MPa . Prospect i ve clinical studies on cervical restorations ( Class V ) with an observation period of at least 18 months were search ed in the literature . The clinical outcome variables were retention loss , marginal discoloration and marginal integrity . Furthermore , an index was formulated to be better able to compare the laboratory and clinical results . Estimates of adhesive effects in a linear mixed model were used to summarize the clinical performance of each adhesive between 12 and 36 months . Spearman correlations between these clinical performances and the μTBS values were calculated subsequently . RESULTS Thirty-six clinical studies with 15 adhesive/restorative systems for which μTBS data were also available were included in the statistical analysis . In general 3-step and 2-step etch- and -rinse systems showed higher bond strength values than the 2-step/3-step self-etching systems , which , however , produced higher values than the 1-step self-etching and the resin modified glass ionomer systems . Prolonged water storage of specimens result ed in a significant decrease of the mean bond strength values in 5 adhesive systems ( Wilcoxon , p<0.05 ) . There was a significant correlation between μTBS values both after 8 h and 6 months of storage and marginal discoloration ( r=0.54 and r=0.67 , respectively ) . However , the same correlation was not found between μTBS values and the retention rate , clinical index or marginal integrity . SIGNIFICANCE As μTBS data of adhesive systems , especially after water storage for 6 months , showed a good correlation with marginal discoloration in short-term clinical Class V restorations , longitudinal clinical trials should explore whether early marginal staining is predictive for future retention loss in non-carious cervical restorations
There is not enough evidence to support one adhesive or bonding strategy over another for treatment of NCCLs .
CLINICAL SIGNIFICANCE Studies with low overall risk of bias demonstrated good clinical performance for adhesives with all four bonding strategies .
However , included studies showed wide variation between adhesives of the same category
OBJECTIVES To establish whether simplified adhesives ( self-etch ) are as clinical ly effective as conventional adhesives ( etch- and -rinse ) with multiple application steps for treatment of non-carious cervical lesions ( NCCLs ) .
NULL HYPOTHESIS there is no difference in the clinical effectiveness of the four different bonding strategies : Three-step etch- and -rinse ; Two-step etch- and -rinse ; Two-step self-etch ; One-step self-etch for treatment of NCCLs .