Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
Effect of an Oat Bran Enriched Diet on the Atherogenic Lipid Profile in Patients with an Increased Coronary Heart Disease Risk
Aim : To study whether an oat bran enriched diet has a specific effect in lowering total and low-density lipoprotein cholesterols , in addition to caloric and fat restriction . Methods : We performed a r and omized , controlled , parallel-group , single-centre study in which 1,994 patients from the Wehrawald Hospital ( Todtmoos , Germany ) were screened and 235 met the criteria male gender , hypercholesterolemia , and overweight . All patients in the Wehrawald Hospital took part in a 4-week st and ardized inpatient lifestyle health program consisting of dietary intervention , increased physical activity , and health education . Caloric restriction , fat modification , and oat bran supplementation were part of the nutritional regimen within the lifestyle health program . Ninety-nine patients were r and omized to a fat-modified diet with caloric restriction and a daily intake of 35–50 g oat bran and 136 patients to a fat-modified , oat bran-free diet with caloric restriction .  Fifty-three male overweight but normocholesterolemic subjects were selected as controls . Results : The most significant decreases in total cholesterol ( –67.7 ± 37.2 mg/dl ; p < 0.01 ) , low-density lipoprotein cholesterol ( –56.3 ± 35.1 mg/dl ; p < 0.01 ) , and apolipoprotein B ( –42.4 ± 34.1 mg/dl ; p < 0.01 ) were found with the combination of the fat-modified and oat bran enriched food . Conclusions : Added to a fat-modified diet , oat bran within a practical range of intake significantly reduces total cholesterol , low-density lipoprotein cholesterol , and apolipoprotein B. These beneficial effects occurred independent of covariables such as physical activity or caloric and fat restriction in the diet
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .