RESULTS Severity of frailty syndrome significantly correlated with post-surgical mortality rates and with many although not all post-surgical complications .
These relationships emerge in different type of surgical procedures and patients ' features .
BACKGROUND Frailty is a geriatric syndrome characterized by the clinical presentation of identifiable physical alterations and decreased physiological reserve .
The assessment of frailty syndrome has been recently related with post-surgical outcomes and overall mortality in older individuals .
Frailty and delayed graft function in kidney transplant recipients.
The ability to predict outcomes following a kidney transplant is limited by the complex physiologic decline of kidney failure , a latent factor that is difficult to capture using conventional comorbidity assessment . The frailty phenotype is a recently described inflammatory state of increased vulnerability to stressors result ing from decreased physiologic reserve and dysregulation of multiple physiologic systems . We hypothesized that frailty would be associated with delayed graft function , based on putative associations between inflammatory cytokines and graft dysfunction . We prospect ively measured  frailty  in 183 kidney transplant recipients between December 2008 and April 2010 . Independent associations between frailty and delayed graft function were analyzed using modified Poisson regression . Preoperative frailty was independently associated with a 1.94-fold increased risk for delayed graft function ( 95 % CI , 1.13 - 3.36 ; P = .02 ) . The assessment of frailty may provide further insights into the pathophysiology of allograft dysfunction and may improve our ability to preoperatively risk-stratify kidney transplant recipients
RESULTS Severity of frailty syndrome significantly correlated with post-surgical mortality rates and with many although not all post-surgical complications .
These relationships emerge in different type of surgical procedures and patients ' features .
BACKGROUND Frailty is a geriatric syndrome characterized by the clinical presentation of identifiable physical alterations and decreased physiological reserve .
The assessment of frailty syndrome has been recently related with post-surgical outcomes and overall mortality in older individuals .