We found a continuing trend towards conducting DCEs across a broader range of countries .
However , the trend towards including fewer attributes was reversed , whilst the trend towards interview-based DCEs reversed because of increased computer administration .
The trend towards using more flexible econometric models , including mixed logit and latent class , has also continued .
Reporting of monetary values has fallen compared with earlier periods , but the proportion of studies estimating trade-offs between health outcomes and experience factors , or valuing outcomes in terms of utility scores , has increased , although use of odds ratios and probabilities has declined .
The reassuring trend towards the use of more flexible and appropriate DCE design s and econometric methods has been reinforced by the increased use of qualitative methods to inform DCE processes and results .
However , qualitative research methods are being used less often to inform attribute selection , which may make DCEs more susceptible to omitted variable bias if the decision framework is not known prior to the research project .
Background Discrete choice experiments ( DCEs ) are increasingly used in health economics to address a wide range of health policy-related concerns .
Objective Broadly adopting the methodology of an earlier systematic review of health-related DCEs , which covered the period 2001–2008 , we report whether earlier trends continued during 2009–2012 .
Discrete Choice Experiment to Evaluate Factors That Influence Preferences for Antibiotic Prophylaxis in Pediatric Oncology
Background Bacterial and fungal infections in pediatric oncology patients cause morbidity and mortality . The clinical utility of antimicrobial prophylaxis  in children is uncertain and the personal utility of these agents is disputed . Objectives were to use a discrete choice experiment to : ( 1 ) describe the importance of attributes to parents and healthcare providers when deciding between use and non-use of antibacterial and antifungal prophylaxis ; and ( 2 ) estimate willingness-to-pay for prophylactic strategies . Methods Attributes were chances of infection , death and side effects , route of administration and cost of pharmacotherapy . Respondents were r and omized to a discrete choice experiment outlining hypothetical treatment options to prevent antibacterial or antifungal infections . Each respondent was presented 16 choice tasks and was asked to choose between two unlabeled treatment options and an opt-out alternative ( no prophylaxis ) . Results 102 parents and 60 healthcare providers participated . For the antibacterial discrete choice experiment , frequency of administration was significantly associated with utility for parents but not for healthcare providers . Increasing chances of infection , death , side effects and cost were all significantly associated with decreased utility for parents and healthcare providers in both the antibacterial and antifungal discrete choice experiment . Parental willingness-to-pay was higher than healthcare providers for both strategies . Conclusion Chances of infection , death , side effects and costs were all significantly associated with utility . Parents have higher willingness-to-pay for these strategies compared with healthcare providers . This knowledge can help to develop prophylaxis programs
We found a continuing trend towards conducting DCEs across a broader range of countries .
However , the trend towards including fewer attributes was reversed , whilst the trend towards interview-based DCEs reversed because of increased computer administration .
The trend towards using more flexible econometric models , including mixed logit and latent class , has also continued .
Reporting of monetary values has fallen compared with earlier periods , but the proportion of studies estimating trade-offs between health outcomes and experience factors , or valuing outcomes in terms of utility scores , has increased , although use of odds ratios and probabilities has declined .
The reassuring trend towards the use of more flexible and appropriate DCE design s and econometric methods has been reinforced by the increased use of qualitative methods to inform DCE processes and results .
However , qualitative research methods are being used less often to inform attribute selection , which may make DCEs more susceptible to omitted variable bias if the decision framework is not known prior to the research project .
Background Discrete choice experiments ( DCEs ) are increasingly used in health economics to address a wide range of health policy-related concerns .
Objective Broadly adopting the methodology of an earlier systematic review of health-related DCEs , which covered the period 2001–2008 , we report whether earlier trends continued during 2009–2012 .