AUTHORS ' CONCLUSIONS Addition of ox and rolone to the GH therapy led to a modest increase in the final adult height of girls aged up to 18 years with TS .
BACKGROUND The final adult height of untreated girls aged up to 18 years with Turner syndrome ( TS ) is approximately 20 cm shorter compared with healthy females .
Treatment with growth hormone ( GH ) increases the adult height of people with TS .
The effects of adding the and rogen , ox and rolone , in addition to GH are unclear .
Therefore , we conducted this systematic review to investigate the benefits and harms of ox and rolone as an adjuvant therapy for people with TS treated with GH .
OBJECTIVES To assess the effects of ox and rolone on growth hormone-treated girls aged up to 18 years with Turner syndrome .
Anabolic Effects of Oxandrolone After Severe Burn
Objective To explore the hypothesis that ox and rolone may reverse muscle catabolism in cachectic , critically ill pediatric burn patients . Summary Background Data Severe burn causes exaggerated muscle protein catabolism , contributing to weakness and delayed healing .  Ox and rolone is an anabolic steroid that has been used in cachectic hepatitis and AIDS patients . Methods Fourteen severely burned children were enrolled during a 5-month period in a prospect i ve cohort analytic study . There was a prolonged delay in the arrival of these patients to the burn unit for definitive care . This neglect of skin grafting and nutritional support result ed in critically ill children with significant malnutrition . On arrival , all patients underwent excision and skin grafting and received similar clinical care . Subjects were studied 5 to 7 days after admission , and again after 1 week of ox and rolone treatment at 0.1 mg/kg by mouth twice daily or no pharmacologic treatment .  Muscle protein kinetics were derived from femoral arterial and venous blood sample s and vastus lateralis muscle biopsies during a stable isotope infusion . Results Control and ox and rolone subjects were similar in age , weight , and percentage of body surface area burned . Muscle protein net balance decreased in controls and improved in the ox and rolone group . The improvement in the ox and rolone group was associated with increased protein synthesis efficiency . Muscle protein breakdown was unchanged . Conclusions In burn victims , ox and rolone improves muscle protein metabolism through enhanced protein synthesis efficiency . These findings suggest the efficacy of ox and rolone in impeding muscle protein catabolism in cachectic , critically injured children
AUTHORS ' CONCLUSIONS Addition of ox and rolone to the GH therapy led to a modest increase in the final adult height of girls aged up to 18 years with TS .
BACKGROUND The final adult height of untreated girls aged up to 18 years with Turner syndrome ( TS ) is approximately 20 cm shorter compared with healthy females .
Treatment with growth hormone ( GH ) increases the adult height of people with TS .
The effects of adding the and rogen , ox and rolone , in addition to GH are unclear .
Therefore , we conducted this systematic review to investigate the benefits and harms of ox and rolone as an adjuvant therapy for people with TS treated with GH .
OBJECTIVES To assess the effects of ox and rolone on growth hormone-treated girls aged up to 18 years with Turner syndrome .