In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .
Effect of zinc supplementation on plasma high-density lipoprotein cholesterol and zinc.
The recent report by Hooper PL , et al. ( JAMA 1980;244:1960 - 1 ) that pharmacological doses ( 160 mg ) of zinc lowered high-density lipoprotein (HDL)-cholesterol in men and that zinc might be an atherogenic agent prompted this report of the effect of zinc supplementation on HDL-cholesterol in women . Four levels of zinc supplements ( 0 , 15 , 50 , or 100 mg/day ) were given to 32 women for 8 wk . Fasting plasma HDL-cholesterol and zinc  were measured at biweekly intervals . Plasma zinc increased in the supplemented groups , peaked at wk 4 , then decreased toward initial values . The decline in plasma zinc regardless of continuing zinc administration may reflect a homeostatic response . No significant differences were seen in HDL-cholesterol over the 8 wk except in the 100 mg group at wk 4 when a transient decrease , -8.4 % ( 57 to 48 mg/dl , p less than 0.04 ) was observed . Thus we conclude that in women the reduction in HDL-cholesterol in response to the pharmacological doses of zinc used in this study was transient and not dose-related
In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .