RESULTS The present study indicated that the efficacy of various fiber supplements on losing weight is variable .
Several mechanisms related to physicochemical properties of fibers such as solubility , fermentability and viscosity rates can be involved in their anti-obesity effects .
Dextrin , Mannan ( gum Arabic ) and pectin-rich fiber ( lupin kernel ) with no dietary interventions indicated a reduction in body weight and energy intake , while from clinical point of view , their effects were not considerable .
Overall , findings indicated that the efficacy of fiber supplements on obesity management is dependent on their contents and physicochemical properties .
It seems that fiber supplements with no weight-loss interventions did not have considerable antiobesity effects .
BACKGROUND Previous trials have reported beneficial effects of isolated and complex fiber supplements in obesity treatment .
However , recommending fiber supplements in obese subjects remains controversial .
To the best of our knowledge , no systematic review has up date d the data on the effects of fiber supplements on obesity since 2010 and the need exists for a systematic review on this topic .
Accordingly , a systematic review was undertaken to summarize the efficacy of different types of fiber supplements as a complementary treatment for weight management .
The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults.
Lupin kernel fiber beneficially modifies  blood lipids  because of its bile acid-binding capacity . The aim of this study was to evaluate the preventive effects of a lupin kernel fiber preparation on cardiovascular diseases and to clarify possible mechanisms . In a r and omized , double-blind , controlled crossover trial , 60 moderately hypercholesterolemic adults ( plasma total cholesterol : > 5.2 mmol/L ) passed 3 intervention periods in different orders with a 2-wk washout phase between each . Participants consumed either a high-fiber diet containing 25-g/d lupin kernel fiber ( LF ) or citrus fiber ( CF ) , or a low-fiber control diet ( CD ) for 4 wk each . Anthropometric , plasma , and fecal variables were assessed at baseline and after the interventions . Contrary to the CF period , total ( 9 % ) and LDL ( 12 % ) cholesterol as well as triacylglycerols ( 10 % ) were lower after the LF period when compared with the CD period [ P ≤ 0.02 , adjusted for baseline , age , gender , and body mass index ( BMI ) ] . HDL cholesterol remained unchanged . Moreover , the LF period reduced high-sensitivity C-reactive protein ( P = 0.02 ) and systolic blood pressure ( P = 0.01 ) when compared with baseline . Bile acid binding could not be shown because the excretion of total bile acids remained constant after the high-fiber diets . However , the LF period result ed in an enhanced formation of the main short-chain fatty acids in comparison with the CD period . During the CF period , only acetate increased significantly . Both high-fiber diets led to higher satiety and modified nutritional behavior , result ing in significantly lower body weight , BMI , and waist circumference compared with the CD period . The blood lipid-lowering effects of LF are apparently not a result of bile acid binding . Rather , we hypothesize for the first time , to our knowledge , that the blood lipid-lowering effects of LF may be mainly attributed to the formation of short-chain fatty acids , specifically propionate and acetate . This trial was registered at clinical trials.gov as NCT01035086
RESULTS The present study indicated that the efficacy of various fiber supplements on losing weight is variable .
Several mechanisms related to physicochemical properties of fibers such as solubility , fermentability and viscosity rates can be involved in their anti-obesity effects .
Dextrin , Mannan ( gum Arabic ) and pectin-rich fiber ( lupin kernel ) with no dietary interventions indicated a reduction in body weight and energy intake , while from clinical point of view , their effects were not considerable .
Overall , findings indicated that the efficacy of fiber supplements on obesity management is dependent on their contents and physicochemical properties .
It seems that fiber supplements with no weight-loss interventions did not have considerable antiobesity effects .
BACKGROUND Previous trials have reported beneficial effects of isolated and complex fiber supplements in obesity treatment .
However , recommending fiber supplements in obese subjects remains controversial .
To the best of our knowledge , no systematic review has up date d the data on the effects of fiber supplements on obesity since 2010 and the need exists for a systematic review on this topic .
Accordingly , a systematic review was undertaken to summarize the efficacy of different types of fiber supplements as a complementary treatment for weight management .