Dosage of pharmacologic medication and length of follow-up did not affect changes in domain scores .
WHOQOL-BREF and ASI domain scoring is a useful tool in measuring overall quality of life and levels of addiction among OST participants .
BACKGROUND Opioid substitution treatment ( OST ) can increase quality of life ( WHOQOL-BREF ) and reduce addiction severity index ( ASI ) scores among participants over time .
OST program participants have noted that improvement in quality of life is one of the most important variables to their reduction in drug use .
However , there is little systematic underst and ing of WHOQOL-BREF and ASI domain changes among OST participants in low and middle-income countries ( LMIC ) .
The effectiveness of methadone maintenance treatment: an overview.
This paper review s the evidence for the effectiveness of methadone maintenance as used in the treatment of opioid dependence . Findings from r and omized controlled trials and observational studies suggest that methadone maintenance reduces heroin use , crime , injection-related risk behaviours and premature mortality among people dependent on opioids . The research further suggests that two aspects of treatment are important in ensuring this effectiveness . Methadone treatment is more effective when higher doses ( > 50 mg ) are employed and , overall , the evidence suggests that a treatment goal of successful maintenance on methadone rather than total abstinence is appropriate . The importance of ancillary services in treatment outcome is less clear and is the subject of current research and debate
Dosage of pharmacologic medication and length of follow-up did not affect changes in domain scores .
WHOQOL-BREF and ASI domain scoring is a useful tool in measuring overall quality of life and levels of addiction among OST participants .
BACKGROUND Opioid substitution treatment ( OST ) can increase quality of life ( WHOQOL-BREF ) and reduce addiction severity index ( ASI ) scores among participants over time .
OST program participants have noted that improvement in quality of life is one of the most important variables to their reduction in drug use .
However , there is little systematic underst and ing of WHOQOL-BREF and ASI domain changes among OST participants in low and middle-income countries ( LMIC ) .