Overall , these aggregations of data provide evidence that DHIs can reduce CVD outcomes and have a positive impact on risk factors for CVD
OBJECTIVE To assess the potential benefit of digital health interventions ( DHIs ) on  cardiovascular disease ( CVD ) outcomes ( CVD events , all-cause mortality , hospitalizations ) and risk factors compared with non-DHIs .
[Effectiveness of an intervention to provide information to patients with hypertension as short text messages and reminders sent to their mobile phone (HTA-Alert)].
OBJECTIVE To analyze the effect of an intervention to provide information with mobile phone text messages to patients with hypertension on compliance with therapy for hypertension . DESIGN Comparative , controlled , multicenter , r and omized cluster study . SETTING 26 primary care health centers in Spain . PARTICIPANTS 26 research ers were r and omized to a control group or an intervention group ( 52 patients each , for a total of 104 patients ) . All patients were receiving monotherapy for uncontrolled hypertension . INTERVENTION Patients in the control group received their physician 's usual interventions . Patients in the intervention group received messages and reminders sent to their mobile phones 2 days per week during 4 months . MAIN OUTCOME MEASURES Tablets were counted and blood pressure was measured at the start of the study and 1 , 3 , and 6 months later . The percentage of compliers , mean percentage of compliance and degree of control of hypertension were compared . The reduction in absolute and relative risk was calculated , as was the number of individuals needed to treat to avoid noncompliance . RESULTS The results were evaluated for a total of 67 individuals ( 34 in the intervention group and 33 in the control group ) . The rate of compliance was 85.1 % ( CI , 74.9%-95.3 % ) overall , 85.7 % ( CI , 70.5%-100.9 % ) in the control group and 84.4 % in the intervention group ( CI , 70.7%-95.3 % ) ( P = NS ) . Mean percentage compliance was 90.2%+/-16.3 % overall , 88.1%+/-20.8 % in the control group and 91.9%+/-11.6 % in the intervention group ( P = NS ) . The percentage of patients whose hypertension was controlled at the end of the study was 51.5 % ( CI , 34.4%-68.6 % ) in the control group and 64.7 % ( CI , 48.6%-80.8 % ) in the intervention group ( P = NS ) . CONCLUSIONS The telephone messaging intervention with alerts and reminders sent to mobile phones did not improve compliance with therapy in patients with hypertension
Overall , these aggregations of data provide evidence that DHIs can reduce CVD outcomes and have a positive impact on risk factors for CVD
OBJECTIVE To assess the potential benefit of digital health interventions ( DHIs ) on  cardiovascular disease ( CVD ) outcomes ( CVD events , all-cause mortality , hospitalizations ) and risk factors compared with non-DHIs .