Robust statistically significant effects were found for improved diet , aerobic exercise , alcohol and sodium restriction , and fish oil supplements : mean reductions in systolic blood pressure of 5.0 mmHg [ 95 % confidence interval ( CI ) : 3.1 - 7.0 ] , 4.6 mmHg ( 95 % CI : 2.0 - 7.1 ) , 3.8 mmHg ( 95 % CI : 1.4 - 6.1 ) , 3.6 mmHg ( 95 % CI : 2.5 - 4.6 ) and 2.3 mmHg ( 95 % CI : 0.2 - 4.3 ) , respectively , with corresponding reductions in diastolic blood pressure .
Relaxation significantly reduced blood pressure only when compared with non-intervention controls .
We found no robust evidence of any important effect on blood pressure of potassium , magnesium or calcium supplements .
Available evidence does not support relaxation therapies , calcium , magnesium or potassium supplements to reduce blood pressure
PURPOSE To quantify effectiveness of lifestyle interventions for hypertension .
Does baseline serum total calcium level influence the blood pressure response to calcium supplementation? A double-blind study.
This was a r and omized and double-blind study to examine : ( 1 ) the effect of a 1500 mg/day calcium supplement vs a placebo for 8 wk in 42 adults with high normal or mildly elevated blood pressure ( BP ) and , ( 2 ) the relationship between baseline serum total calcium levels and BP response to calcium supplementation . Following the experimental protocol , mean pressures were lower in the treatment vs placebo group ( 95.7 mmHg and 102.1 mmHg , p = 0.002 ) , but response was not related to initial serum total calcium levels . After 8 wk of calcium supplementation , serum total calcium was greater in the treatment group compared to the placebo group ( p = 0.02 ) . Within the treatment group only , the change in total serum calcium was related to the change in parathyroid hormone ( r = -0.92 , p = 0.0002 ) ; and the change in ionized calcium was related to the change in parathyroid hormone ( r = -0.68 , p = 0.03 ) in the subgroup with low baseline serum total calcium . This study provides further support for the hypotensive effect of supplemental calcium in some people . However , it fails to clarify or exp and upon previous reports that a low serum total calcium level might be predictive of the blood pressure response to increased calcium
Robust statistically significant effects were found for improved diet , aerobic exercise , alcohol and sodium restriction , and fish oil supplements : mean reductions in systolic blood pressure of 5.0 mmHg [ 95 % confidence interval ( CI ) : 3.1 - 7.0 ] , 4.6 mmHg ( 95 % CI : 2.0 - 7.1 ) , 3.8 mmHg ( 95 % CI : 1.4 - 6.1 ) , 3.6 mmHg ( 95 % CI : 2.5 - 4.6 ) and 2.3 mmHg ( 95 % CI : 0.2 - 4.3 ) , respectively , with corresponding reductions in diastolic blood pressure .
Relaxation significantly reduced blood pressure only when compared with non-intervention controls .
We found no robust evidence of any important effect on blood pressure of potassium , magnesium or calcium supplements .
Available evidence does not support relaxation therapies , calcium , magnesium or potassium supplements to reduce blood pressure
PURPOSE To quantify effectiveness of lifestyle interventions for hypertension .