D and PA+D  interventions had larger effects on glucose reduction  than PA alone .
Lifestyle  interventions significantly improved FPG , HbA1c , FI , HOMA-IR , and bodyweight among adults without IGT or diabetes , and might reduce progression of hyperglycemia to type 2 diabetes mellitus
This study systematic ally assessed the effectiveness of lifestyle interventions on glycemic indicators among adults ( ⩾18years ) without IGT or diabetes .
Long-term effects of a very low calorie diet (Nutrilett®) in obesity treatment. A prospective, randomized, comparison between VLCD and a hypocaloric diet+behavior modification and their combination
OBJECTIVES . To compare weight loss on a balanced hypocaloric diet to that of a Very Low Calorie Diet ( VLCD ) after two months of treatment and to further compare 26 months of weight maintenance and safety with or without VLCD assistance in obese patients . DESIGN . Prospect i ve , r and omized , controlled intervention trial , initially with two and later with three parallel groups . SETTING . Swedish University out-patient obesity clinic . SUBJECTS . Eighty-one obese patients of both gender with a BMI ≥30 kg/m2 from the waiting list participated in a structured weight reduction+weight maintenance programme . INTERVENTION . Twenty-seven patients ( group A ) were r and omized to a balanced diet of 6720 kJ/d ( 1600 kcal/d ) during the whole treatment period . The other patients ( n=54 ) were r and omized to VLCD ( Nutrilett ® ) 1764 kJ/d ( 420 kcal/d ) diet during the first two months . The VLCD treated patients were rer and omized after the initial treatment to the well balanced hypocaloric diet ( 6720 kJ/d ) with ( group C ) or without ( group B ) 1 MJ of VLCD to be taken during the evening . MAIN OUTCOME MEASURES . During the first two-month period , the mean body weight loss in the VLCD group was 18.9±7.1 kg compared to 7.2±4.8 kg in the diet treated group , with a similar relative fat loss assessed by bioimpedance of 68 % and 76 % respectively . The maintained weight loss in all groups after 28 months of treatment was 10.9±10.2 kg in the 52 % who completed the programme . Weight losses and drop-out rates were similar in all three groups . CONCLUSIONS . Twenty-four months weight maintenance and drop out rates are independent of whether the initial treatment commences with VLCD or a hypocaloric diet . One MJ nutrition powder taken freely does not affect 24 months weight maintenance on a hypocaloric ( 6.7 MJ/d ) diet
D and PA+D  interventions had larger effects on glucose reduction  than PA alone .
Lifestyle  interventions significantly improved FPG , HbA1c , FI , HOMA-IR , and bodyweight among adults without IGT or diabetes , and might reduce progression of hyperglycemia to type 2 diabetes mellitus
This study systematic ally assessed the effectiveness of lifestyle interventions on glycemic indicators among adults ( ⩾18years ) without IGT or diabetes .