Vitamin D supplementation had no statistically significant effects on total body bone mineral content ( BMC ) , hip bone mineral density ( BMD ) or forearm BMD .
These results do not support vitamin D supplementation to improve bone density in healthy children with normal vitamin D levels , but suggest that supplementation of deficient children may be clinical ly useful .
BACKGROUND Results of r and omised controlled trials ( RCTs ) of vitamin D supplementation to improve  bone density in children are inconsistent .
OBJECTIVES To determine the effectiveness of vitamin D supplementation for improving  bone mineral density in children , whether any effect varies by sex , age or pubertal stage , the type or dose of vitamin D given or baseline vitamin D status , and if effects persist after cessation of supplementation .
Seasonal and geographical variations in the growth rate of infants in China receiving increasing dosages of vitamin D supplements.
In theory , sunshine exposure is sufficient to maintain normal vitamin D concentrations for the optimal growth of newborn infants . To determine whether season of birth , latitude ( north v. south ) and increasing dosages of vitamin D supplements would influence the growth rate for the first 6 months of life , 255 healthy fall- and spring-born infants from two northern and two southern cities in China were r and omly assigned to receive either 100 , 200 , or 400 IU of vitamin D a day . The study showed that season of birth and dose of vitamin D did not affect the growth rate of infants born in the same latitude , but a significant difference was found in the gain in length over the 6-month period between infants from the north and infants from the south ( P = 0.0001 ) . Regional differences among the Chinese people , other than sunshine exposure , may have influenced the difference in length gain
Vitamin D supplementation had no statistically significant effects on total body bone mineral content ( BMC ) , hip bone mineral density ( BMD ) or forearm BMD .
These results do not support vitamin D supplementation to improve bone density in healthy children with normal vitamin D levels , but suggest that supplementation of deficient children may be clinical ly useful .
BACKGROUND Results of r and omised controlled trials ( RCTs ) of vitamin D supplementation to improve  bone density in children are inconsistent .
OBJECTIVES To determine the effectiveness of vitamin D supplementation for improving  bone mineral density in children , whether any effect varies by sex , age or pubertal stage , the type or dose of vitamin D given or baseline vitamin D status , and if effects persist after cessation of supplementation .