RESULTS ( 1 ) EQ-5D was valid and responsive for skin conditions and most cancers ; in vision , its performance varied according to aetiology ; and performance was poor for hearing impairments .
The HUI3 performed well for hearing and vision disorders .
It also performed well in cancers although evidence was limited and there was no evidence in skin conditions .
Response mapping using all the domain scores was the best performing model for the EORTC QLQ-C30 .
In an exploratory analysis , a limited dependent variable mixture model performed better than an equivalent linear model .
3 ) The exploratory valuation study found that bolt-on items for vision , hearing and tiredness had a significant impact on values of the health states , but the direction and magnitude of differences depended on the severity of the health state .
The vision bolt-on item had a statistically significant impact on EQ-5D health state values and a full valuation model was estimated .
EQ-5D performs well in studies of cancer and skin conditions .
Mapping techniques provide a solution to predict EQ-5D values where EQ-5D has not been administered .
For conditions where EQ-5D was found to be inappropriate , including some vision disorders and for hearing , bolt-ons provide a promising solution .
BACKGROUND The National Institute for Health and Care Excellence recommends the use of generic preference-based measures ( GPBMs ) of health for its Health Technology Assessment s ( HTAs ) .
However , these data may not be available or appropriate for all health conditions .
OBJECTIVES To determine whether GPBMs are appropriate for some key conditions and to explore alternative methods of utility estimation when data from GPBMs are unavailable or inappropriate .
( 2 ) Potential modelling approaches to ' map ' EQ-5D values from condition-specific and clinical measures of health [ European Organisation for Research and Treatment of Cancer Quality -of-life Question naire Core 30 ( EORTC QLQ-C30 ) and Functional Assessment of Cancer Therapy - General Scale ( FACT-G ) ] are compared for predictive ability and goodness of fit using two separate data sets . (
Societal effects of hearing aid fitting among the moderately hearing impaired: Efectos sociales de la adaptación de auxiliares auditivos en pacientes con impedimentos auditivos moderados
The objective of this study was to evaluate  hearing aid fitting  from a societal viewpoint , rather than the more traditional patient perspective . The effects of hearing aid fitting on generic quality of life ( EuroQol ) , social functioning ( SF36 ) , auditory disability , productivity at paid and unpaid labour , and medical consumption , were assessed in a prospect i ve study among 80 moderately hearingimpaired first-time hearing aid applicants . The study showed that hearing aid fitting solved problems with paid employment , but did not seem to affect unpaid work . Use of medical services remained relatively stable after first-time hearing aid fitting . The Amsterdam Inventory proved to be a useful question naire to assess the effects on hearing disability . No effects of hearing aid fitting on generic quality of life could be determined with the EuroQol , while hearing aid fitting did lead to an improvement in one aspect of generic quality of life ; namely social functioning . El objetivo de este estudio fue evaluar la adaptación de auxiliares auditivos desde un punto de vista social , más que desde la perspective tradicional del paciente . Los efectos de la adaptación de auxiliares auditivos en la calidad genérica de vida ( EuroQWol ) , funcionamiento social ( SF36 ) , discapacidad auditiva , productividad en el trabajo remunerado o no remunerado , además de gastos médicos , fueron evaluados en un estudio prospect ivo con 80 pacientes con impedimentos auditivos moderados a quienes se les adaptó por primera vez un auxiliar auditivo . El estudio mostró que la adaptación de auxiliares auditivos resuelve problemas en los empleos remunerados pero no parece afectar el trabajo sin remuneración . El uso de servicios médicos permaneció relativamente estable después de la primera adaptación . El cuestionario Amsterdam probó ser un instrumento útil para evaluar los efectos en la discapacidad auditiva . No se pudieron determinar los efectos de la adaptación de auxiliares auditivos en la calidad genérica de vida por medio del EuroQol , mientras que la adaptación de auxiliares auditivos condicionó la mejoría en un aspecto de la calidad genérica de vida , que es concretamente , el funcionamiento social
RESULTS ( 1 ) EQ-5D was valid and responsive for skin conditions and most cancers ; in vision , its performance varied according to aetiology ; and performance was poor for hearing impairments .
The HUI3 performed well for hearing and vision disorders .
It also performed well in cancers although evidence was limited and there was no evidence in skin conditions .
Response mapping using all the domain scores was the best performing model for the EORTC QLQ-C30 .
In an exploratory analysis , a limited dependent variable mixture model performed better than an equivalent linear model .
3 ) The exploratory valuation study found that bolt-on items for vision , hearing and tiredness had a significant impact on values of the health states , but the direction and magnitude of differences depended on the severity of the health state .
The vision bolt-on item had a statistically significant impact on EQ-5D health state values and a full valuation model was estimated .
EQ-5D performs well in studies of cancer and skin conditions .
Mapping techniques provide a solution to predict EQ-5D values where EQ-5D has not been administered .
For conditions where EQ-5D was found to be inappropriate , including some vision disorders and for hearing , bolt-ons provide a promising solution .
BACKGROUND The National Institute for Health and Care Excellence recommends the use of generic preference-based measures ( GPBMs ) of health for its Health Technology Assessment s ( HTAs ) .
However , these data may not be available or appropriate for all health conditions .
OBJECTIVES To determine whether GPBMs are appropriate for some key conditions and to explore alternative methods of utility estimation when data from GPBMs are unavailable or inappropriate .
( 2 ) Potential modelling approaches to ' map ' EQ-5D values from condition-specific and clinical measures of health [ European Organisation for Research and Treatment of Cancer Quality -of-life Question naire Core 30 ( EORTC QLQ-C30 ) and Functional Assessment of Cancer Therapy - General Scale ( FACT-G ) ] are compared for predictive ability and goodness of fit using two separate data sets . (