While no clinical trial to date has specifically targeted fatigue , r and omized controlled trials , systematic review s , and meta-analyses indicate that treatment modalities studied in the context of other fibromyalgia symptoms could also improve fatigue .
Fatigue is a disabling , multifaceted symptom that is highly prevalent and stubbornly persistent .
Although fatigue is a frequent complaint among patients with fibromyalgia , it has not received the same attention as pain .
Reasons for this include lack of st and ardized nomenclature to communicate about fatigue , lack of evidence -based guidelines for fatigue assessment , and a deficiency in effective treatment strategies .
Fatigue does not occur in isolation ; rather , it is present concurrently in varying severity with other fibromyalgia symptoms such as chronic widespread pain , unrefreshing sleep , anxiety , depression , cognitive difficulties , and so on .
Survey-based and preliminary mechanistic studies indicate that multiple symptoms feed into fatigue and it may be associated with a variety of physiological mechanisms .
Health status and disease severity in fibromyalgia: results of a six-center longitudinal study.
OBJECTIVE To determine the intermediate and long-term outcomes of fibromyalgia in patients seen in rheumatology centers in which there is special interest in the syndrome . METHODS We conducted a longitudinal outcome study by mailed comprehensive Health Assessment Question naire administered every 6 months to 538 patients , from 6 rheumatology centers , whose median duration of disease at first assessment was 7.8 years . The final assessment took place after 7 years . In addition , there was study followup on 85 patients who had attended the Wichita center for > 10 years . RESULTS Although functional disability worsened slightly and health satisfaction improved slightly , measures of pain , global severity , fatigue , sleep disturbance , anxiety , depression , and health status were markedly abnormal at study initiation and were essentially unchanged over the study period . Correlations between first and last assessment values were as high as r = 0.82 . For some variables , abnormalities were 3 times greater at one center compared with another . CONCLUSION Patients with established fibromyalgia , seen in rheumatology centers in which there a special interest in the disease and followed up for as long as 7 years , have markedly abnormal scores for pain , functional disability , fatigue , sleep disturbance , and psychological status , and these values do not change substantially over time . Half the patients are dissatisfied with their health , and 59 % rate their health as fair or poor . There are marked differences in disease severity among the various centers , but < 14 % of the variance in outcomes can be explained by demographic or center factors . Values at the first assessment are predictive of final values
While no clinical trial to date has specifically targeted fatigue , r and omized controlled trials , systematic review s , and meta-analyses indicate that treatment modalities studied in the context of other fibromyalgia symptoms could also improve fatigue .
Fatigue is a disabling , multifaceted symptom that is highly prevalent and stubbornly persistent .
Although fatigue is a frequent complaint among patients with fibromyalgia , it has not received the same attention as pain .
Reasons for this include lack of st and ardized nomenclature to communicate about fatigue , lack of evidence -based guidelines for fatigue assessment , and a deficiency in effective treatment strategies .
Fatigue does not occur in isolation ; rather , it is present concurrently in varying severity with other fibromyalgia symptoms such as chronic widespread pain , unrefreshing sleep , anxiety , depression , cognitive difficulties , and so on .
Survey-based and preliminary mechanistic studies indicate that multiple symptoms feed into fatigue and it may be associated with a variety of physiological mechanisms .