RESULTS Although causality is unclear , heavy and dependent cannabis use is consistently associated with a high prevalence of comorbid psychiatric disorders and learning and memory impairments that seem to recover after a period of abstinence .
Evidence regarding other cognitive domains and neurological consequences including cerebrovascular events is limited and inconsistent .
Abstinence after treatment is only achieved in a minority of cases ; treatment targeted at reduction in use appears have some success .
Potential moderators of the impact of CUD on the brain include age of onset , heaviness of use , CUD severity , the ratio of ∆9-tetrahydrocannabinol to cannabidiol , and severity of comorbid disorders .
Current evidence of long-term effects of daily cannabis use and cannabis use disorder on brain-related outcomes is suggestive rather than conclusive but use is associated with psychiatric morbidity and with cognitive impairments that recover after a period of abstinence
AIMS To summarize and evaluate our knowledge of the relationship between heavy cannabis use , Cannabis Use Disorder ( CUD ) , and the brain .
Inhibitory control contributes to "motor"--but not "cognitive"--impulsivity.
Literature on impulsivity regularly cl aims inhibitory control deficits underlie impulsive behavior . The current study investigated whether taxing inhibitory control will increase reflection ( decision making under conditions of uncertainty ) , temporal ( delay of gratification ) , and motor impulsivity ( behavioral disinhibition ) . Inhibitory control was challenged , via a r and om letter generation task presented during responding to three impulsivity measures : the Information Sampling Task ( IST ) , Single Key Impulsivity Paradigm , and the Stop Signal Task ( SST ) .  Participants ( n = 33 ) were assigned to the inhibitory control challenging ( experimental ) condition , or to a control condition in which inhibitory control was not challenged . The SST was affected by the inhibitory control challenge : participants in the experimental condition displayed increased motor impulsivity , evidence d in longer stop signal reaction times ( SSRTs ) compared to the control group . The manipulation did not affect reflection- or temporal- impulsivity measures . These data support the suggestion that the mechanisms underlying the motor subtype of impulsivity are dissociable from the temporal and reflection subtypes , and that engagement of inhibitory control is not necessary to prevent impulsive decision making
RESULTS Although causality is unclear , heavy and dependent cannabis use is consistently associated with a high prevalence of comorbid psychiatric disorders and learning and memory impairments that seem to recover after a period of abstinence .
Evidence regarding other cognitive domains and neurological consequences including cerebrovascular events is limited and inconsistent .
Abstinence after treatment is only achieved in a minority of cases ; treatment targeted at reduction in use appears have some success .
Potential moderators of the impact of CUD on the brain include age of onset , heaviness of use , CUD severity , the ratio of ∆9-tetrahydrocannabinol to cannabidiol , and severity of comorbid disorders .
Current evidence of long-term effects of daily cannabis use and cannabis use disorder on brain-related outcomes is suggestive rather than conclusive but use is associated with psychiatric morbidity and with cognitive impairments that recover after a period of abstinence
AIMS To summarize and evaluate our knowledge of the relationship between heavy cannabis use , Cannabis Use Disorder ( CUD ) , and the brain .