There was no important clinical meaningful benefit .
Adverse effectsWe found very low- quality evidence of the effect of exercise versus either no intervention , or usual care .
We found moderate- to low- quality evidence that exercise programmes probably slightly improve function , may reduce pain , and probably slightly reduce global patient assessment of disease activity , when compared with no intervention , and measured upon completion of the programme .
We found moderate- to low- quality evidence that exercise programmes probably have little or no effect on improving function or reducing pain , when compared with usual care , and may have little or no effect on reducing patient assessment of disease activity , when measured upon completion of the programmes .
We are uncertain whether exercise programmes improve spinal mobility , reduce fatigue , or induce adverse effects
BACKGROUND Exercise programmes are often recommended for managing ankylosing spondylitis ( AS ) , to reduce pain and improve or maintain functional capacity .
OBJECTIVES To assess the benefits and harms of exercise programmes for people with AS .
Rehabilitation Treatment in Patients with Ankylosing Spondylitis Stabilized with Tumor Necrosis Factor Inhibitor Therapy. A Randomized Controlled Trial
Objective . To assess the 2- ( T1 ) and 6-month ( T2 ) followup effects on pain , spine mobility , physical function , and disability outcome of a rehabilitation intervention in patients with ankylosing spondylitis ( AS ) stabilized with tumor necrosis factor ( TNF ) inhibitor therapy . Methods . Sixty-two out patients ( 49 men , 13 women , mean age 47.5 ± 10.6 yrs ) were r and omized to rehabilitation plus an educational-behavioral ( n = 20 ) program , to an educational-behavioral program only ( n = 20 ) , or to a control group ( n = 22 ) . The educational-behavioral program included 2 educational meetings and 12 rehabilitation exercise sessions ( stretching , strengthening , chest and spine/hip joint flexibility exercises ) , which patients then performed at home . Outcome assessment at the end of rehabilitation training ( T1 ) and at T2 was based on spinal pain intensity in the previous 4 weeks by self-report visual analog scale ( VAS ; 100 mm : 0 = no pain , 100 = maximum pain ) , BASMI , BASFI , BASDAI , and on chest expansion and the active range of motion of the cervical and lumbar spine measured by a pocket goniometer . Results . The 3 groups were comparable at baseline . On intragroup comparison at T1 , the rehabilitation group showed significant improvement in the BASMI and BASDAI , in chest expansion , and in most spinal active range of motion measurements . BASFI and cervical and lumbar VAS scores improved in both the rehabilitation and educational-behavioral groups . The positive results achieved in the rehabilitation group were maintained at the 6-month followup . Conclusion . Combining intensive group exercise with an educational-behavioral program can provide promising results in the management of patients with clinical ly stabilized AS on TNF inhibitor treatment
There was no important clinical meaningful benefit .
Adverse effectsWe found very low- quality evidence of the effect of exercise versus either no intervention , or usual care .
We found moderate- to low- quality evidence that exercise programmes probably slightly improve function , may reduce pain , and probably slightly reduce global patient assessment of disease activity , when compared with no intervention , and measured upon completion of the programme .
We found moderate- to low- quality evidence that exercise programmes probably have little or no effect on improving function or reducing pain , when compared with usual care , and may have little or no effect on reducing patient assessment of disease activity , when measured upon completion of the programmes .
We are uncertain whether exercise programmes improve spinal mobility , reduce fatigue , or induce adverse effects
BACKGROUND Exercise programmes are often recommended for managing ankylosing spondylitis ( AS ) , to reduce pain and improve or maintain functional capacity .
OBJECTIVES To assess the benefits and harms of exercise programmes for people with AS .