Meta- analysis revealed few clinical ly relevant and statistically significant benefits of " add-on " therapies on exercise performance compared with exercise training .
The aim of this review was to identify the effectiveness of therapies added on to conventional exercise training to maximise exercise capacity in patients with chronic obstructive pulmonary disease ( COPD ) .
Osteopathic manipulative treatment effectiveness in severe chronic obstructive pulmonary disease: a pilot study.
OBJECTIVES Few and contrastingly data are available about use of osteopathic manipulative treatment ( OMT ) in patients with chronic obstructive pulmonary disease ( COPD ) . DESIGN Comparing the effects of the combination of pulmonary rehabilitation and OMT compared with pulmonary rehabilitation ( PR ) in patients with severely impaired COPD . SETTING Rehabilitative pulmonary department . INTERVENTIONS Patients underwent exercise training , OMT , educational support and nutritional and psychological counselling . MAIN OUTCOMES MEASURES Exercise capacity through 6 min walk test ( 6MWT-- primary outcome ) and pulmonary function test ( secondary outcomes ) were evaluated at the beginning and at the end of the training . Patients were r and omly assigned to receive PR+soft manipulation ( G1 ) or OMT+PR ( G2 ) for 5 days/week for 4 weeks . RESULTS 20 stable COPD patients ( 5 female -- mean age , 63.8±5.1 years ; FEV1 26.9±6.3 % of predicted ) referred for in-patient pulmonary rehabilitation were evaluated . Respect to the baseline , 6 MWT statistically improved in both group . In particular , G2 group gained 72.5±7.5 m ( p=0.01 ) and G1 group 23.7±9.7 m. Between group comparison showed a difference of 48.8 m ( 95 % CI : 17 to 80.6 m , p=0.04 ) . Moreover , in G2 group we showed a decrease in residual volume ( RV -- from 4.4±1.5 l to 3.9±1.5 l , p=0.05 ) . Between group comparison showed an important difference ( -0.44 l ; 95 % CI : -0.26 to -0.62 l , p=0.001 ) . Furthermore , only in G2 group we showed an increase in FEV1 . CONCLUSIONS This study suggests that OMT+PR may improve exercise capacity and reduce RV in severely impaired COPD patients with respect to PR alone
Meta- analysis revealed few clinical ly relevant and statistically significant benefits of " add-on " therapies on exercise performance compared with exercise training .
The aim of this review was to identify the effectiveness of therapies added on to conventional exercise training to maximise exercise capacity in patients with chronic obstructive pulmonary disease ( COPD ) .