Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .
Extracorporeal magnetic stimulation is of limited clinical benefit to women with idiopathic detrusor overactivity: a randomized sham controlled trial.
OBJECTIVES To observe the effect of both acute and medium-term magnetic stimulation of the pelvic floor on detrusor function amongst women with idiopathic detrusor overactivity ( IDO ) . METHODS Two separate studies were undertaken amongst women with a sole diagnosis of IDO . The first study assessed the acute effect of magnetic stimulation ( provided by Neocontrol ) on detrusor function during the filling phase of st and ard cystometry . Multiple filling cycles were performed with stimulation at a different key moment in each . This was done to establish that the device could influence the detrusor . Subsequently , a r and omized sham control trial was performed to assess clinical efficacy . A total of 20 treatments , each of 20 minutes duration , were administered over six weeks with follow-up six weeks thereafter . Half the patients received therapy from a genuine device , the others receiving fake treatment on an identical looking/sounding sham device . The sham device contained a deflector plate to de grade the magnetic field and was located in a separate room . Outcome measures included changes in a 24 hour fluid volume chart , urine loss ( 24 hour pad test ) and quality of life instruments . RESULTS Amongst 10 patients receiving stimulation during cystometry , volume at first involuntary detrusor contraction during filling rose from a median value of 240ml ( Inter-quartile range ( IQR ) 210 - 300 ) to 285ml ( IQR 231 - 320 ) , p = 0.03 and maximum detrusor pressure decreased from 40 cm water ( IQR 34 - 45 ) to 33 cm water ( IQR 25 - 41 ) , p<0.01 . The RCT was completed by 29 of 44 ( 66 % ) recruits . Of these , 15 of 29 ( 52 % ) received active treatment and 14 of 29 ( 48 % ) sham therapy . Active therapy significantly reduced the number of urge episodes per day , p<0.01 . With respect to baseline , actively treated patients experienced significant reduction in voids per day and quality of life but this trend did not reach significance when compared to the sham group , partly due to unexpected difficulty in recruitment which yielded an underpowered sample size for these outcome measures . CONCLUSIONS Magnetic stimulation reduces detrusor contractility in the acute phase of administration . Although the treatment was well tolerated and urge episodes reduced following prolonged therapy , no statistically significant improvement was observed in quality of life indices or measured 24 hour urinary loss . The treatment can not be recommended for women with IDO
Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .