Hydralazine was the most common drug for others to be evaluated against .
Diazoxide , given as 75 mg bolus injections , appears to be associated with maternal hypotension requiring treatment , and ketanserin is less effective than hydralazine at reducing blood pressure .
There is no other clear evidence that any one of the other antihypertensive agents is better than another for women with severe hypertension during pregnancy .
Exceptions are diazoxide and ketanserin , which are probably not good choices
BACKGROUND Very high blood pressure during pregnancy poses a serious threat to women and their babies .
The use of drugs to lower blood pressure will reduce this risk for the women , and possibly also for the baby .
OBJECTIVES The objective of this review was to compare different antihypertensive drugs used for treatment of severe hypertension during pregnancy .
[The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension].
OBJECTIVE To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension ( PIH ) . METHODS 64 cases of PIH were r and omly divided into study group ( n = 32 ) and control group ( n = 32 ) . Before labor Nifedipine 10 mg-20 mg was given three time daily for all cases . In study group Nifedipine was taken orally every 6 hours during the labor course until the end of second stage . In control group Nifedipine was not given in the labor stages . The postpartum blood loss was collected and measured carefully within 2 hours after delivery . RESULTS The amount of pastpartum hemorrhage was ( 359.1 + /- 136.6 ) ml in study group which was significantly higher than that of control group ( 268.5 + /- 110.7 ) ml P < 0.01 . The postpartum hemorrhage rate in study and control group was 43.75 % and 18.75 % respectively . The difference was statistically significant ( P < 0.05 ) . CONCLUSION During labor using Nifedipine for PIH cases can increase the amount of postpartum blood loss and rate of postpartum hemorrnage
Hydralazine was the most common drug for others to be evaluated against .
Diazoxide , given as 75 mg bolus injections , appears to be associated with maternal hypotension requiring treatment , and ketanserin is less effective than hydralazine at reducing blood pressure .
There is no other clear evidence that any one of the other antihypertensive agents is better than another for women with severe hypertension during pregnancy .
Exceptions are diazoxide and ketanserin , which are probably not good choices
BACKGROUND Very high blood pressure during pregnancy poses a serious threat to women and their babies .
The use of drugs to lower blood pressure will reduce this risk for the women , and possibly also for the baby .
OBJECTIVES The objective of this review was to compare different antihypertensive drugs used for treatment of severe hypertension during pregnancy .