Results show that various classes of antidepressants exert improving effects on cognitive function across several cognitive domains .
Specifically , studies suggest that SSRIs , the SSRE tianeptine , the SNRI duloxetine , vortioxetine and other antidepressants such as bupropion and moclobemide may exert certain improving effects on cognitive function in depression , such as in learning and memory and executive function .
The few non-pharmacological studies conducted employing cognitive orientated treatments and cognitive remediation therapy show promising results for the improvement of cognitive impairment in depression .
Cognitive dysfunction is of clinical significance and exerts longst and ing implication on patients ׳ function .
Pharmacological and non-pharmacological treatments of cognitive dysfunction are emerging .
This review evaluates pharmacological and non-pharmacological treatments of cognitive impairment primarily in the domains of memory , attention , processing speed and executive function in clinical depression .
Successful computer-assisted cognitive remediation therapy in patients with unipolar depression: a proof of principle study.
BACKGROUND Despite increasing awareness of the extent and severity of cognitive deficits in major depressive disorder ( MDD ) , trials of cognitive remediation have not been conducted . We conducted a 10-week course of cognitive remediation in patients with long-term MDD to probe whether deficits in four targeted cognitive domains , ( i ) memory , ( ii ) attention , ( iii ) executive functioning and ( iv ) psychomotor speed , could be improved by this intervention . METHOD We administered a computerized cognitive retraining package ( PSSCogReHab ) with demonstrated efficacy to 12 stable patients with recurrent MDD . Twelve matched patients with MDD and a group of healthy control participants were included for comparison ; neither comparator group received the intervention that involved stimulation of cognitive functions through targeted , repetitive exercises in each domain . RESULTS Patients who received cognitive training improved on a range of neuropsychological tests targeting attention , verbal learning and memory , psychomotor speed and executive function . This improvement exceeded that observed over the same time period in a group of matched comparisons . There was no change in depressive symptom scores over the course of the trial , thus improvement in cognitive performance occurred independent of other illness variables . CONCLUSIONS These results provide preliminary evidence that improvement of cognitive functions through targeted , repetitive exercises is a viable method of cognitive remediation in patients with recurrent MDD
Results show that various classes of antidepressants exert improving effects on cognitive function across several cognitive domains .
Specifically , studies suggest that SSRIs , the SSRE tianeptine , the SNRI duloxetine , vortioxetine and other antidepressants such as bupropion and moclobemide may exert certain improving effects on cognitive function in depression , such as in learning and memory and executive function .
The few non-pharmacological studies conducted employing cognitive orientated treatments and cognitive remediation therapy show promising results for the improvement of cognitive impairment in depression .
Cognitive dysfunction is of clinical significance and exerts longst and ing implication on patients ׳ function .
Pharmacological and non-pharmacological treatments of cognitive dysfunction are emerging .
This review evaluates pharmacological and non-pharmacological treatments of cognitive impairment primarily in the domains of memory , attention , processing speed and executive function in clinical depression .