Noninducibility of VT after VT ablation is associated with improved arrhythmia-free survival and all-cause mortality
BACKGROUND Although ventricular tachycardia ( VT ) ablation is a widely used therapy for patients with VT , the ideal end points for this procedure are not well defined .
We performed a meta- analysis of the published literature to assess the predictive value of noninducibility of postinfa rct ion VT for long-term outcomes after VT ablation .
Effect of increased current, multiple pacing sites and number of extrastimuli on induction of ventricular tachycardia.
Reproduction of  spontaneously occurring ventricular tachycardia ( VT ) and induction of previously undocumented VT were studied prospect ively in 98 patients : 48 with documented sustained VT or ventricular fibrillation , 25 with nonsustained or exercise-induced VT , and 25 with no documented VT . Patients received 1 to 4 ventricular extrastimuli and ventricular burst pacing at 2 right ventricular ( RV ) sites , first at twice late diastolic threshold , and then at 10 mA using a prospect i ve , t and em study design . Spontaneously occurring VT was reproduced in 37 of 48 patients ( 77 % ) at twice late diastolic threshold and in 1 other patient ( 2 % ) at 10 mA. VT was reproduced at both RV sites in 17 of 48 patients ( 35 % ) and at 1 site in 20 of 48 patients ( 42 % ) at twice late diastolic threshold . A previously undocumented VT was induced in 7 of 25 patients ( 28 % ) with no documented VT at twice diastolic threshold and 14 of 25 patients ( 56 % ) at 10 mA. A previously undocumented VT was induced in 33 of 73 patients ( 45 % ) with a history of sustained or nonsustained VT at twice late diastolic threshold and in 47 of 73 patients ( 64 % ) at 10 mA. In patients with documented sustained VT , the use of up to 4 ventricular extrastimuli at multiple RV sites increases the sensitivity of the test . In patients without documented VT , the induction of previously undocumented VT with more than 3 ventricular extrastimuli limits the specificity of the test . Increased current provides only a slight advantage over 4 ventricular extrastimuli at twice late diastolic threshold in terms of reproduction of spontaneously occurring VT , but leads to a marked increase in induction of previously undocumented VT
Noninducibility of VT after VT ablation is associated with improved arrhythmia-free survival and all-cause mortality
BACKGROUND Although ventricular tachycardia ( VT ) ablation is a widely used therapy for patients with VT , the ideal end points for this procedure are not well defined .
We performed a meta- analysis of the published literature to assess the predictive value of noninducibility of postinfa rct ion VT for long-term outcomes after VT ablation .