Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .
Randomized controlled trial of testosterone in myotonic dystrophy
Because testosterone has an anabolic effect in myotonic dystrophy , we conducted a 12-month , r and omized , double-blind therapeutic trial of testosterone enanthate ( 3 mg/kg/wk ) in 40 men with myotonic dystrophy . We evaluated strength by manual muscle tests , quantitative myometry , pulmonary function , and quantitative functional assessment . A sustained , significant elevation of testosterone levels was produced but there was no effect on any measurement of muscle strength . Muscle mass as estimated by creatinine excretion and lean body mass ( 40 K method ) increased significantly . We conclude that testosterone does not improve strength in myotonic dystrophy despite increasing muscle mass
Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .