Several studies of good quality demonstrated changes in lifestyle habits arising from the provision of genetic interventions .
The most promising lifestyle changes were changes in nutrition .
Conclusions : It is possible to facilitate behaviour change using genetic testing as the catalyst .
Background : Study ing the impact of  genetic testing interventions on lifestyle behaviour change  has been a priority area of research in recent years .
Substantial heterogeneity exists in the results and conclusions of this literature , which has yet to be explained using vali date d behaviour change theory and an assessment of the quality of genetic interventions .
The theory of planned behaviour ( TPB ) helps to explain key contributors to behaviour change .
It has been hypothesized that personalization could be added to this theory to help predict changes in health behaviours .
Purpose : This systematic review provides a detailed , comprehensive identification , assessment , and summary of primary research articles pertaining to  lifestyle behaviour change  ( nutrition , physical activity , sleep , and smoking ) result ing from  genetic testing interventions .
The present review further aims to provide in-depth analyses of studies conducted to date within the context of the TPB and the quality of genetic interventions provided to participants while aim ing to determine whether or not genetic testing facilitates changes in lifestyle habits .
This review is timely in light of a recently published “ call-to-action ” paper , highlighting the need to incorporate the TPB into personalized healthcare behaviour change research .
Incorporating genetic susceptibility feedback into a smoking cessation program for African-American smokers with low income.
PURPOSE Markers of genetic susceptibility to tobacco-related cancers could personalize harms of smoking and motivate cessation . Our objective was to assess whether a multicomponent intervention that included feedback about genetic susceptibility to lung cancer increased risk perceptions and rates of smoking cessation compared with a st and ard cessation intervention . EXPERIMENTAL DESIGN Our design was a two-arm trial with eligible smokers r and omized in a 1:2 ratio to Enhanced Usual Care or Biomarker Feedback ( BF ) .  Surveys were conducted at baseline , 6 , and 12 months later . The setting was an inner city community health clinic . African-American patients who were current smokers ( n = 557 ) were identified by chart abstract ion and provider referral . All smokers received a self-help manual and , if appropriate , nicotine patches . Smokers in the BF arm also were offered a blood test for genotyping the GST(3 ) gene ( GSTM1 ) , sent a test result booklet , and called up to four times by a health educator . Prevalent abstinence was assessed by self-report of having smoked no cigarettes in the prior 7 days at the 6- and 12-month follow-ups and sustained abstinence , i.e. , not smoking at either follow-up or in-between . RESULTS Smoking cessation was greater for the BF arm than the Enhanced Usual Care arm ( 19 % versus 10 % , respectively ; P < 0.006 ) at 6 months but not at 12 months . CONCLUSIONS Smokers agreed to genetic feedback as part of a multicomponent cessation program . Although the program increased short-term cessation rates compared with st and ard intervention , genetic feedback of susceptibility may not benefit smokers with high baseline risk perceptions
Several studies of good quality demonstrated changes in lifestyle habits arising from the provision of genetic interventions .
The most promising lifestyle changes were changes in nutrition .
Conclusions : It is possible to facilitate behaviour change using genetic testing as the catalyst .
Background : Study ing the impact of  genetic testing interventions on lifestyle behaviour change  has been a priority area of research in recent years .
Substantial heterogeneity exists in the results and conclusions of this literature , which has yet to be explained using vali date d behaviour change theory and an assessment of the quality of genetic interventions .
The theory of planned behaviour ( TPB ) helps to explain key contributors to behaviour change .
It has been hypothesized that personalization could be added to this theory to help predict changes in health behaviours .
Purpose : This systematic review provides a detailed , comprehensive identification , assessment , and summary of primary research articles pertaining to  lifestyle behaviour change  ( nutrition , physical activity , sleep , and smoking ) result ing from  genetic testing interventions .
The present review further aims to provide in-depth analyses of studies conducted to date within the context of the TPB and the quality of genetic interventions provided to participants while aim ing to determine whether or not genetic testing facilitates changes in lifestyle habits .
This review is timely in light of a recently published “ call-to-action ” paper , highlighting the need to incorporate the TPB into personalized healthcare behaviour change research .