Although a variety of pain and physical functioning outcome measures have been reported in the literature , few have demonstrate method ologically strong psychometric properties .
INTRODUCTION A range of outcome measures across various domains are used to evaluate change following an intervention in clinical trials on chronic neuropathic pain ( NeP ) .
However , to capture a real change in the variable of interest , the psychometric properties of a particular measure should demonstrate appropriate method ological quality .
Various outcome measures in the domains of pain and physical functioning have been used in the literature for NeP , for which individual properties ( eg , reliability/validity ) have been reported .
The Impact of Acute Herpes Zoster Pain and Discomfort on Functional Status and Quality of Life in Older Adults
Objectives To describe the interference of herpes zoster ( HZ ) pain and discomfort with activities of daily living ( ADLs ) and health-related quality of life ( HRQL ) during the acute rash phase , and to quantify the relationship between acute HZ pain and discomfort and impaired ADLs and HRQL in older persons . Methods Prospect i ve , observational study of 160 HZ out patients age ≥60 at 4 US study sites who completed the Zoster Brief Pain Inventory ( ZBPI ) , Zoster Impact Question naire ( ZIQ ) , McGill Pain Question naire , EuroQol , and SF-12 question naires on a predetermined schedule . Patients rated interference on a 0 to 10 scale for ADL items in the ZBPI and the ZIQ . Interference scores were averaged to create summary measures for the ZBPI items ( ZBPI ADLI ) and ZIQ items ( ZIQ ADLI ) . A composite pain score was used in mixed-effects models analyses of the association between pain and discomfort and ADLI and HRQL measures during the first 35 days after HZ rash onset . Results HZ pain interfered with all ADLs but interference was greatest for enjoyment of life , sleep , general activity , leisure activities , getting out of the house , and shopping . For every 1.0 point increase in pain and discomfort intensity , there was a 0.69 and 0.53 point increase in ZBPI and ZIQ interference , respectively , and a 2.81 point , 1.57 point , and 1.95 point decrease in EuroQol , SF-12 physical , and SF-12 mental scales , respectively . Discussion Acute zoster pain and discomfort has a significant negative impact on functional status and HRQL in older adults . The magnitude of interference increases with increasing pain and discomfort intensity
Although a variety of pain and physical functioning outcome measures have been reported in the literature , few have demonstrate method ologically strong psychometric properties .
INTRODUCTION A range of outcome measures across various domains are used to evaluate change following an intervention in clinical trials on chronic neuropathic pain ( NeP ) .
However , to capture a real change in the variable of interest , the psychometric properties of a particular measure should demonstrate appropriate method ological quality .
Various outcome measures in the domains of pain and physical functioning have been used in the literature for NeP , for which individual properties ( eg , reliability/validity ) have been reported .