Clinicians and patients should beware of possible decreases in the systemic bioavailability of conventional drugs when taken concomitantly with St John 's wort
OBJECTIVE To determine the method ological quality of clinical trials that examined possible interactions of St John 's wort with conventional drugs , and to examine the results of these trials .
Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)
Extracts of St John 's wort ( Hypericum perforatum ) are widely used in the treatment of depression , often as an over‐the‐counter drug . In contrast to its frequent use , knowledge about the pharmacokinetics of ingredients and drug interactions of St John 's wort is poor . We studied the interaction between hypericum extract LI160 and digoxin
Clinicians and patients should beware of possible decreases in the systemic bioavailability of conventional drugs when taken concomitantly with St John 's wort
OBJECTIVE To determine the method ological quality of clinical trials that examined possible interactions of St John 's wort with conventional drugs , and to examine the results of these trials .