Subgroup analyses showed that using whole flaxseed in doses ≥30 g d-1 , longer-term interventions ( ≥12 weeks ) and studies including participants with higher BMI ( ≥ 27 kg m-2 ) had positive effects on body composition  .
Whole flaxseed is a good choice for weight management particularly for weight reduction in overweight and obese participants
Flaxseed consumption may be inversely associated with obesity ; however , findings of available r and omized controlled trials ( RCTs ) are conflicting .
The present study aim ed to systematic ally review and analyse RCTs assessing the effects of flaxseed consumption on body weight and body composition .
Effect of flaxseed oil on serum systemic and vascular inflammation markers and oxidative stress in hemodialysis patients: a randomized controlled trial
Purpose The aim of this study was to investigate the effects of flaxseed oil consumption on serum systemic and vascular inflammation markers , and oxidative stress in hemodialysis ( HD ) patients . Methods In this r and omized , double-blind , clinical trial , 34 HD patients were r and omly assigned to either the flaxseed oil or the control group . The patients in the flaxseed oil group received 6 g/day flaxseed oil for 8 week , whereas the control group received 6 g/day medium-chain triglycerides ( MCT ) oil . At baseline and the end of week 8 , serum concentrations of high-sensitive C-reactive protein ( hs-CRP ) , soluble intercellular adhesion molecule type 1 ( sICAM-1 ) , soluble vascular cell adhesion molecule type 1 ( sVCAM-1 ) , sE-selectin , and malondialdehyde ( MDA ) were measured after a 12- to 14-h fast . Results Serum hs-CRP , a systemic inflammation marker , and sVCAM-1 , a vascular inflammation marker , reduced significantly in the flaxseed oil group at the end of week 8 compared to baseline ( P < 0.05 ) , and the reductions were significant in comparison with the MCT oil group ( P < 0.05 ) . There were no significant differences between the two groups in mean changes in serum sICAM-1 , sE-selectin , and MDA . Conclusion This study indicates that daily consumption of 6 g flaxseed oil reduces serum hs-CRP and sVCAM-1 , which are two risk factors for CVD . Therefore , the inclusion of flaxseed oil in the usual diet of HD patients can be considered as a strategy for reducing CVD risk factors
Subgroup analyses showed that using whole flaxseed in doses ≥30 g d-1 , longer-term interventions ( ≥12 weeks ) and studies including participants with higher BMI ( ≥ 27 kg m-2 ) had positive effects on body composition  .
Whole flaxseed is a good choice for weight management particularly for weight reduction in overweight and obese participants
Flaxseed consumption may be inversely associated with obesity ; however , findings of available r and omized controlled trials ( RCTs ) are conflicting .
The present study aim ed to systematic ally review and analyse RCTs assessing the effects of flaxseed consumption on body weight and body composition .