Our case study successfully enabled us to address the four feasibility metrics , and we provide new information on management feasibility ( i.e. estimate data completeness and estimate data entry ) and scientific outcomes feasibility ( i.e. determining data collection material s appropriateness ) .
Conclusion Our review highlights the existing research and provides a case study which assesses important metrics of study feasibility .
Background Much research has been undertaken to establish the important benefits of physical activity in persons with multiple sclerosis ( MS ) .
There is disagreement regarding the strength of this research , perhaps because the majority of studies on physical activity and its benefits have not undergone initial and systematic feasibility testing .
We aim to address the feasibility processes that have been examined within the context of physical activity interventions in MS .
Treadmill training for individuals with multiple sclerosis: a pilot randomised trial
This pilot study investigated whether 4 weeks of aerobic treadmill training in individuals with multiple sclerosis ( MS )  improved mobility and reduced fatigue .  Individuals with MS were recruited to this prospect i ve , r and omised controlled trial . Individuals were assessed at baseline , week 7 and 12 with a 10 metre timed walk , a 2 minute walk , the Rivermead Mobility Index , and the Fatigue Severity Scale . After a pre- assessment familiarisation session and a baseline assessment , individuals were r and omly allocated to an initial intervention or delayed intervention group . Treadmill training consisted of 4 weeks of supervised aerobic exercise delivered weeks 3–6 in the immediate group and 8–11 in the delayed group . Of the initial 19 recruits , 16 individuals completed the study . There was a significant difference in walking endurance between the delayed and immediate groups at baseline ( p<0.05 ) . On re assessment in week 7 , decreases in 10 metre walk time were found in both groups , which was significant in the immediate group ( p<0.05 ) . The 2 minute walk distance significantly increased in both groups ( p<0.05 ) . In the training group , reassessed at week 12 after training ceased , there was a return towards baseline scores . No significant changes in fatigue scores were found . This study showed that in individuals with MS  , aerobic treadmill training is feasible and well tolerated . Walking speed and endurance increased following training with no increase in reported fatigue . Detraining occurred in the period following training . A larger r and omised clinical trial is warranted
Our case study successfully enabled us to address the four feasibility metrics , and we provide new information on management feasibility ( i.e. estimate data completeness and estimate data entry ) and scientific outcomes feasibility ( i.e. determining data collection material s appropriateness ) .
Conclusion Our review highlights the existing research and provides a case study which assesses important metrics of study feasibility .
Background Much research has been undertaken to establish the important benefits of physical activity in persons with multiple sclerosis ( MS ) .
There is disagreement regarding the strength of this research , perhaps because the majority of studies on physical activity and its benefits have not undergone initial and systematic feasibility testing .
We aim to address the feasibility processes that have been examined within the context of physical activity interventions in MS .