There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula.
BACKGROUND While there is a large body of data on the effects of long-chain polyunsaturated fatty acid supplementation of infant formula on visual and cognitive maturation during infancy , longterm visual and cognitive outcome data from r and omized trials are scarce . AIM To evaluate docosahexaenoic acid ( DHA ) and arachidonic acid (ARA)-supplementation of infant formula on visual and cognitive outcomes at 4 years of age . METHODS Fifty-two of 79 healthy term infants who were enrolled in a single-center , double-blind , r and omized clinical trial of DHA and ARA supplementation of infant formula were available for follow-up at 4 years of age . In addition , 32 breast-fed infants served as a " gold st and ard " . Outcome measures were visual acuity and the Wechsler Preschool and Primary Scale of Intelligence -- Revised . RESULTS At 4 years , the control formula group had poorer visual acuity than the breast-fed group ; the DHA- and DHA+ARA-supplemented groups did not differ significantly from the breast-fed group . The control formula and DHA-supplemented groups had Verbal IQ scores poorer than the breast-fed group . CONCLUSION DHA and ARA-supplementation of infant formula supports visual acuity and IQ maturation similar to that of breast-fed infants
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .