Findings were mixed and showed various effects of cannabinoid administration on several aspects of sleep .
This paper review s the literature regarding the effects of cannabinoid administration on  sleep in humans .
Reinforcing and subjective effects of oral delta 9-THC and smoked marijuana in humans.
The reinforcing and subjective effects of oral delta-9-tetrahydrocannabinol ( THC ) and smoked marijuana were studied in two groups of regular marijuana users . One group ( N = 10 ) was tested with smoked marijuana and the other ( N = 11 ) with oral THC .  Reinforcing effects were measured with a discrete-trial choice procedure which allowed subjects to choose between the self-administration of active drug or placebo on two independent occasions . Subjective effects and heart rate were measured before and after drug administration . Smoked active marijuana was chosen over placebo on both choice occasions by all subjects . Similarly , oral THC was chosen over placebo on both occasions by all but one subject . Both active drug treatments produced qualitatively and quantitatively similar subjective effects , and both significantly increased heart rate , although the time course of effects differed substantially between the two treatments . The results demonstrate that both smoked marijuana and oral THC can serve as positive reinforcers in human subjects under laboratory conditions . The experimental paradigm used here should prove useful for identifying factors that influence the self-administration of marijuana and other cannabinoids by humans
Findings were mixed and showed various effects of cannabinoid administration on several aspects of sleep .
This paper review s the literature regarding the effects of cannabinoid administration on  sleep in humans .