The most under-reported items were concealment of allocation , blinding of patients and outcome assessors , intention to treat and validation of outcomes .
BACKGROUND In the process of conducting a systematic review on interventions for skin lesions due to neuritis in leprosy , we assessed several primary papers with respect to the quality of reporting and methods used in the studies .
Awareness of what constitutes weak points in previously conducted studies may be used to improve the planning , conducting and reporting of future clinical trials .
AIMS To assess the quality of reporting and of methodology  in studies of interventions for skin lesions due to neuritis in leprosy .
Use of topical ketanserin for the treatment of ulcers in leprosy patients.
A comparative study was carried out in which 66 leprosy patients with ulcers were r and omly divided in two groups of 33 patients each : Group A ( experimental group ) was treated with ketanserin gel ( 2 % ) and group B with clioquinol cream and /or Lassar paste during a three month period . At the end of the study , when ulcer sizes in the two groups were compared , the group treated with topical  ketanserin  showed superior results ( p < 0.001 using Kolmogorov-Smirnov 's test ) . We conclude that the drug is useful as coadjuavant treatment for healing ulcers in these patients
The most under-reported items were concealment of allocation , blinding of patients and outcome assessors , intention to treat and validation of outcomes .
BACKGROUND In the process of conducting a systematic review on interventions for skin lesions due to neuritis in leprosy , we assessed several primary papers with respect to the quality of reporting and methods used in the studies .
Awareness of what constitutes weak points in previously conducted studies may be used to improve the planning , conducting and reporting of future clinical trials .
AIMS To assess the quality of reporting and of methodology  in studies of interventions for skin lesions due to neuritis in leprosy .