There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Effect of supplementation of arachidonic acid (AA) or a combination of AA plus docosahexaenoic acid on breastmilk fatty acid composition.
We investigated whether supplementation with arachidonic acid ( 20:4 omega 6 ; AA ) , or a combination of AA and docosahexaenoic acid ( 22:6 omega 3 ; DHA ) would affect  human milk polyunsaturated fatty acid ( PUFA ) composition . Ten women were daily supplemented with 300 mg AA  , eight with 300 mg AA , 110 mg eicosapentaenoic acid ( 20:5 omega 3 ; EPA ) and 400 mg DHA , for one week and eight women served as unsupplemented controls . Milk sample s were collected on days 0 , 1 and 7 . The fatty acid composition of the milk was analyzed by capillary gas chromatography with flame ionisation detection . Supplementation with AA alone had no effect on breastmilk AA , but tended to reduce EPA and DHA levels . Administration of a combination of AA , EPA and DHA tended to increase both milk AA and long chain PUFA (LCPUFA)omega 3 content . A larger simultaneous increase of milk AA , DHA and EPA than observed in the present study can probably be accomplished by the use of a combination of a lower LCPUFA omega 6/LCPUFA omega 3 ratio and higher AA , EPA and DHA dosages
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .