We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .
Can metformin reduce the incidence of gestational diabetes mellitus in pregnant women with polycystic ovary syndrome? Prospective cohort study
Background . Women with polycystic ovary syndrome ( PCOS ) are at a high risk to develop Gestational Diabetes mellitus ( GDM ) . We hypothesized that metformin due to its metabolic , endocrine , vascular , and anti-inflammatory effects may reduce the incidence of GDM in PCOS women . Patient and method . We carried out a prospect i ve cohort study to determine the beneficial effects of metformin on PCOS patients during pregnancy . Three-hundred and sixty non-diabetic PCOS patients were included who were conceived on metformin by different treatment modalities . Two-hundred pregnant women continued on metformin at a dose of 1000–2000 mg daily throughout pregnancy ( study group ) and 160 women discontinued metformin use at the time of conception ( control group ) . Results . There is a statistically significant reduction in the incidence of GDM in favor of metformin group ( OR : 0.17 , 95 % CI : 0.07–0.37 ) . There is a statistically significant reduction in the incidence of pre-eclampsia in favor of metformin group ( OR : 0.35 , 95 % CI : 0.13–0.94 ) . Conclusion . Metformin is a promising medication for the prevention or reduction of the incidence of GDM and pre-eclampsia in PCOS women
We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .