RESULTS Following an extensive review of selected studies from the 201 articles , the studies indicate that each of the psychotropic medications review ed impact alpha , beta , delta and theta waves independently and differently from each other .
Additionally , certain medications , particularly haloperidol and valproic acid , have dissimilar results exemplified in all waveforms .
OBJECTIVES It is known that psychotropic medications have an impact on the readings found in Electroencephalogram ( EEG ) .
In the field of psychiatry , there are several psychotropics utilized by clinicians .
This review seeks to investigate all the available data for psychotropic drugs and their impact on EEG changes .
Effects of sertraline on autonomic and cognitive functions in healthy volunteers
Rationale Though sertraline , a selective serotonin reuptake inhibitor ( SSRI ) , causes autonomic and cognitive adverse events such as dry mouth and somnolence , there is a paucity of appropriately design ed studies on the cognitive and autonomic effects of the drug in the literature . Objective To compare the effects of sertraline on cognitive and autonomic functions with those of placebo in healthy humans . Method A r and omized , double blind , cross over study of 12 healthy male volunteers aged 24 ( 21– 32 ; median ; range ) years . Subjects orally received 50 mg sertraline and placebo once daily for periods of 14 days each with at least 14 days in between . Heart rate variability ( HRV ) , skin conductance level ( SCL ) and skin conductance response ( SCR ) following sudden deep respiration were employed as parameters for autonomic function . Quantitative EEG ( qEEG ) and psychometric tests served as parameters for cognitive function . Measurements were performed repeatedly before the start of drug administration and on the last treatment day . Results Sertraline caused a significant reduction of heart rate and SCL ( P<0.05 ) , whereas HRV and SCR were not changed . Cognitive functions such as flicker fusion frequency , memory , choice reaction time and psychomotor performance were not influenced by sertraline but slow and fast beta power density in the qEEG was increased . Conclusion Cognitive and psychomotor performance are not altered in healthy humans receiving multiple dosing with sertraline . The observed decreases in heart rate and SCL may be due to a sympatho-inhibitory effect of sertraline
RESULTS Following an extensive review of selected studies from the 201 articles , the studies indicate that each of the psychotropic medications review ed impact alpha , beta , delta and theta waves independently and differently from each other .
Additionally , certain medications , particularly haloperidol and valproic acid , have dissimilar results exemplified in all waveforms .
OBJECTIVES It is known that psychotropic medications have an impact on the readings found in Electroencephalogram ( EEG ) .
In the field of psychiatry , there are several psychotropics utilized by clinicians .
This review seeks to investigate all the available data for psychotropic drugs and their impact on EEG changes .