Results show that various classes of antidepressants exert improving effects on cognitive function across several cognitive domains .
Specifically , studies suggest that SSRIs , the SSRE tianeptine , the SNRI duloxetine , vortioxetine and other antidepressants such as bupropion and moclobemide may exert certain improving effects on cognitive function in depression , such as in learning and memory and executive function .
The few non-pharmacological studies conducted employing cognitive orientated treatments and cognitive remediation therapy show promising results for the improvement of cognitive impairment in depression .
Cognitive dysfunction is of clinical significance and exerts longst and ing implication on patients ׳ function .
Pharmacological and non-pharmacological treatments of cognitive dysfunction are emerging .
This review evaluates pharmacological and non-pharmacological treatments of cognitive impairment primarily in the domains of memory , attention , processing speed and executive function in clinical depression .
Changes in cognitive functioning following treatment of late-life depression.
OBJECTIVE Knowledge of the relationship between various clinical characteristics and cognitive functioning is advancing , but little is known about the cognitive response to treatment for geriatric depression . The purpose of this study was to examine the cognitive response to treatment for patients with late-life depression . METHOD Subjects included 45 nondemented , elderly depressed patients who achieved remission after 12 weeks of antidepressant treatment and 20 elderly comparison subjects .  All subjects were administered a battery of clinical measures , including cognitive screening instruments , before and after treatment . RESULTS As a group , the elderly depressed patients showed a small improvement in overall cognitive functioning after treatment . Among depressed patients with concomitant cognitive impairment at baseline , performance on the Mattis Dementia Rating Scale domains of conceptualization and initiation/perseveration improved significantly relative to those of depressed patients with normal cognition . Despite the improvement following treatment , the overall level of cognitive functioning in the elderly depressed patients with cognitive impairment at baseline remained mildly impaired , especially in the memory and initiation/perseveration domains . CONCLUSIONS Elderly depressed patients with cognitive impairment may experience improvement in specific domains following antidepressant treatment but may not necessarily reach normal levels of performance , particularly in memory and executive functions . This subgroup of late-life depression patients is likely at high risk of developing progressive dementia
Results show that various classes of antidepressants exert improving effects on cognitive function across several cognitive domains .
Specifically , studies suggest that SSRIs , the SSRE tianeptine , the SNRI duloxetine , vortioxetine and other antidepressants such as bupropion and moclobemide may exert certain improving effects on cognitive function in depression , such as in learning and memory and executive function .
The few non-pharmacological studies conducted employing cognitive orientated treatments and cognitive remediation therapy show promising results for the improvement of cognitive impairment in depression .
Cognitive dysfunction is of clinical significance and exerts longst and ing implication on patients ׳ function .
Pharmacological and non-pharmacological treatments of cognitive dysfunction are emerging .
This review evaluates pharmacological and non-pharmacological treatments of cognitive impairment primarily in the domains of memory , attention , processing speed and executive function in clinical depression .