Outcomes , such as range of motion , recurrence , and clinical success , were frequently defined , however many different definitions were used .
This systematic review summarizes the outcome reporting st and ards in Dupuytren ’s disease treatment research .
Pain Associated With Treatment of Dupuytren Contracture With Collagenase Clostridium histolyticum.
PURPOSE The primary objective of this study was to quantify the degree of pain associated with collagenase Clostridium histolyticum ( CCH ) injection and to determine whether it is related to other factors in the intervention . METHODS A prospect i ve study of 135 patients was performed to evaluate pain at 3 points during treatment : ( 1 ) after CCH injection , using a numerical rating scale ( NRS ) , ( 2 ) a binary ( positive/negative ) assessment before manipulation 24 hours after CCH and after removing the b and age , and ( 3 ) after joint manipulation performed with wrist block anesthesia . RESULTS The average NRS for pain during infiltration was 4.7 . Pain was present before manipulation in 52.6 % of patients . Pain from manipulation showed an average NRS score of 3.6 . The amounts of pain at CCH infiltration , pain after 24 hours , and pain from the manipulation were correlated because patients who experienced pain during CCH infiltration were more likely to report experiencing pain during manipulation . CONCLUSIONS Collagenase Clostridium histolyticum injection for treating Dupuytren contracture can be a painful process . There is a clear relationship between a patient 's level of pain during injection of CCH and the likelihood that the patient will experience pain during manipulation , even with the use of local anesthesia . TYPE OF STUDY /LEVEL OF EVIDENCE Prognostic IV
Outcomes , such as range of motion , recurrence , and clinical success , were frequently defined , however many different definitions were used .
This systematic review summarizes the outcome reporting st and ards in Dupuytren ’s disease treatment research .