Conclusion : The results from this meta- analysis suggest a beneficial short-term effect of coffee intake on EF as measured by FMD .
Base on systematic review results acute and chronic intake of coffee products may exerts an unfavorable effect on AS .
Background : Endothelial function ( EF ) and arterial stiffness ( AS ) are predictors of cardiovascular disease .
As previous research concerning the effect of coffee intake on EF and AS was controversial , we conducted a systematic review and meta- analysis to synthesize research .
Coffee and green tea as a large source of antioxidant polyphenols in the Japanese population.
Food and beverages rich in polyphenols with antioxidant activity are highlighted as a potential factor for risk reduction of lifestyle related diseases . This study was conducted to eluci date total polyphenol consumption from beverages in Japanese people .  Total polyphenol ( TP ) contents in beverages were measured using a modified Folin-Ciocalteu method removing the interference of reduced sugars by using reverse-phase column chromatography . A beverage consumption survey was conducted in the Tokyo and Osaka areas in 2004 . R and omly selected male and female subjects ( 10 - 59 years old , n = 8768 ) recorded the amounts and types of all nonalcoholic beverages  consumed in a week . Concentration of TP in coffee , green tea , black tea , Oolong tea , barley tea , fruit juice , tomato/vegetable juice , and cocoa drinks were at 200 , 115 , 96 , 39 , 9 , 34 , 69 , and 62 mg/100 mL , respectively . Total consumption of beverages in a Japanese population was 1.11 + /- 0.51 L/day , and TP contents from beverages was 853 + /- 512 mg/day . Coffee and green tea shared 50 % and 34 % of TP consumption in beverages , respectively , and contribution of each of the other beverages was less than 10 % . TP contents in 20 major vegetables and 5 fruits were 0 - 49 mg and 2 - 55 mg/100 g , respectively . Antioxidant activities , Cu reducing power , and scavenging activities for DPPH and superoxide , of those sample s correlated to the TP contents ( p < 0.001 ) . Beverages , especially coffee , contributed to a large share of the consumption of polyphenols , as antioxidants , in the Japanese diet
Conclusion : The results from this meta- analysis suggest a beneficial short-term effect of coffee intake on EF as measured by FMD .
Base on systematic review results acute and chronic intake of coffee products may exerts an unfavorable effect on AS .
Background : Endothelial function ( EF ) and arterial stiffness ( AS ) are predictors of cardiovascular disease .
As previous research concerning the effect of coffee intake on EF and AS was controversial , we conducted a systematic review and meta- analysis to synthesize research .