Based on 88 eligible observational studies , level of evidence grading and quantitative meta-analyses indicated that there is limited available evidence that the total volume or patterns of sedentary behaviour are associated with health in children and adolescents when accounting for moderate-intensity to vigorous-intensity physical activity or focusing on studies with low risk of bias .
Quality evidence from studies with robust design s and methods , objective measures of sitting , examining associations for various health outcomes , is needed to better underst and if the overall volume or patterns of sedentary behaviour are independent determinants of health in children and adolescents
Sedentary behaviour has emerged as a unique determinant of health in adults .
Studies in children and adolescents have been less consistent .
We review ed the evidence to determine if the total volume and patterns ( i.e. breaks and bouts ) of objective ly measured sedentary  behaviour  were associated with adverse health outcomes in young people , independent of moderate-intensity to vigorous-intensity physical activity .
Predictive Validity and Classification Accuracy of ActiGraph Energy Expenditure Equations and Cut-Points in Young Children
Objectives Evaluate the predictive validity of ActiGraph energy expenditure equations and the classification accuracy of physical activity intensity cut-points in preschoolers . Methods Forty children aged 4–6 years ( 5.3±1.0 years ) completed a ∼150-min room calorimeter protocol involving age-appropriate sedentary , light and moderate-to vigorous-intensity physical activities . Children wore an ActiGraph GT3X on the right mid-axillary line of the hip . Energy expenditure measured by room calorimetry and physical activity intensity classified using direct observation were the criterion methods . Energy expenditure was predicted using Pate and Puyau equations . Physical activity intensity was classified using Evenson , Sirard , Van Cauwenberghe , Pate , Puyau , and Reilly , ActiGraph cut-points . Results The Pate equation significantly overestimated VO2 during sedentary behaviors , light physical activities and total VO2 ( P<0.001 ) . No difference was found between measured and predicted VO2 during moderate-to vigorous-intensity physical activities ( P = 0.072 ) . The Puyau equation significantly underestimated activity energy expenditure during moderate-to vigorous-intensity physical activities , light-intensity physical activities and total activity energy expenditure ( P<0.0125 ) . However , no overestimation of activity energy expenditure during sedentary behavior was found . The Evenson cut-point demonstrated significantly higher accuracy for classifying sedentary behaviors and light-intensity physical activities than others . Classification accuracy for moderate-to vigorous-intensity physical activities was significantly higher for Pate than others . Conclusion Available ActiGraph equations do not provide accurate estimates of energy expenditure across physical activity intensities in preschoolers . Cut-points of ≤25counts⋅15 s−1 and ≥420 counts⋅15 s−1 for classifying sedentary behaviors and moderate-to vigorous-intensity physical activities , respectively , are recommended
Based on 88 eligible observational studies , level of evidence grading and quantitative meta-analyses indicated that there is limited available evidence that the total volume or patterns of sedentary behaviour are associated with health in children and adolescents when accounting for moderate-intensity to vigorous-intensity physical activity or focusing on studies with low risk of bias .
Quality evidence from studies with robust design s and methods , objective measures of sitting , examining associations for various health outcomes , is needed to better underst and if the overall volume or patterns of sedentary behaviour are independent determinants of health in children and adolescents
Sedentary behaviour has emerged as a unique determinant of health in adults .
Studies in children and adolescents have been less consistent .
We review ed the evidence to determine if the total volume and patterns ( i.e. breaks and bouts ) of objective ly measured sedentary  behaviour  were associated with adverse health outcomes in young people , independent of moderate-intensity to vigorous-intensity physical activity .