Similarly , there was no clear evidence of effect for cardiovascular risk factors , although again the number of studies reporting these was small .
There was some evidence for beneficial effects on HRQOL , dietary outcomes , and physical activity , although firm conclusions can not yet be made .
The effects on healthcare utilisation and cost-effectiveness are also inconclusive , and trials are yet to measure the impact of  Internet interventions on compliance with medication .
BACKGROUND The Internet could provide a means of delivering secondary prevention programmes to people with coronary heart disease ( CHD ) .
OBJECTIVES To determine the effectiveness of Internet-based interventions targeting lifestyle changes and medicines management for the secondary prevention of CHD .
Electronic prescribing via the internet for a coronary artery disease and hypertension megatrial
A unique feature of the International Verapamil SR/Tr and olapril Study ( INVEST ) is the Internet‐based , electronic data capture system developed at the University of Florida for this trial . This system allows for direct collection of patient enrollment data , r and omization , study drug prescribing , and real‐time monitoring of patient data online . In this trial , immediate transmission of patient‐specific data occurs using online data collection forms . Investigators only need a personal computer with access to the Internet ; no complicated hardware , software systems , or paper storage files are necessary . INVEST is the first large r and omized clinical trial to use electronic prescribing systems in the research setting . Electronic prescribing eliminates errors associated with illegible h and writing , inappropriate dosing , and inappropriate medication choice . Because the INVEST protocol allows flexibility of medication choice and dosage range within r and omly assigned treatment strategies based on patient tolerance and blood pressure response , physician investigators may use individual practice patterns and preferences . The electronic system provides guidance to physicians relative to the addition of medication or dosage adjustments within the protocol . Electronic tracking and reporting mechanisms have enabled investigators in this complex megatrial to enroll , r and omize , and manage patients in real time with great accuracy
Similarly , there was no clear evidence of effect for cardiovascular risk factors , although again the number of studies reporting these was small .
There was some evidence for beneficial effects on HRQOL , dietary outcomes , and physical activity , although firm conclusions can not yet be made .
The effects on healthcare utilisation and cost-effectiveness are also inconclusive , and trials are yet to measure the impact of  Internet interventions on compliance with medication .
BACKGROUND The Internet could provide a means of delivering secondary prevention programmes to people with coronary heart disease ( CHD ) .
OBJECTIVES To determine the effectiveness of Internet-based interventions targeting lifestyle changes and medicines management for the secondary prevention of CHD .