Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .
Weight loss: a novel and effective treatment for urinary incontinence.
PURPOSE We evaluated the effect of weight loss on  urinary incontinence ( UI ) in overweight and obese women . MATERIAL S AND METHODS A r and omized , controlled clinical trial was conducted among overweight and obese women experiencing at least 4 UI episodes per week . Women were r and omly assigned to a 3-month liquid diet weight reduction program ( 24 in the immediate intervention group ) or a wait-list delayed intervention group ( 24 in the wait-list control group ) . Participants in the wait-list control group began the weight reduction program in month 3 of the study . All women were followed for 6 months after completing the weight reduction program . Wilcoxon tests were used to compare intergroup differences in change in weekly UI episodes and quality of life scores . RESULTS A total of 48 women were r and omized and 40 were assessed 3 months after r and omization . Median ( with 25 % to 75 % interquartile range [ IQR ] ) baseline age was 52 years ( IQR 47 to 59 ) , weight was 97 kg ( IQR 87 to 106 ) and UI episodes were 21 weekly ( IQR 11 to 33 ) . Women in the immediate intervention group had a 16 kg ( IQR 9 to 20 ) weight reduction compared with 0 kg ( IQR -2 to 2 ) in the wait-list control group ( p < 0.0001 ) . The immediate intervention group experienced a 60 % reduction ( IQR 30 % to 89 % ) in weekly UI episodes compared with 15 % ( IQR -9 % to 25 % ) in the wait-list control group ( p < 0.0005 ) and had greater improvement in quality of life scores . Stress ( p = 0.003 ) and urge ( p = 0.03 ) incontinent episodes decreased in the immediate intervention vs wait-list control group . Following the weight reduction program the wait-list control group experienced a similar median reduction in weekly UI episodes ( 71 % ) . Among all 40 women  mean weekly UI episodes decreased 54 % ( 95 % CI 40 % to 69 % ) after weight reduction and the improvement was maintained for 6 months . CONCLUSIONS Weight reduction is an effective treatment for overweight and obese women with UI . Weight loss of 5 % to 10 % has an efficacy similar to that of other nonsurgical treatments and should be considered a first line therapy for incontinence
Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .