Conclusion : Positive clinical ly meaningful effects ( > 5 points ) are seen to an age of 36 months , but are no longer present at 5 years
Objective : To determine in a systematic review , whether interventions for infant development that involve parents , improve neurodevelopment at 12 months corrected age or older .
Effect of an early intervention programme on low birthweight infants with cerebral injuries.
OBJECTIVE To determine the effect of an early intervention programme ( EIP ) on low birthweight infants with cerebral injuries . METHODS Subjects were 23 high-risk low birthweight infants ( periventricular leukomalacia 15 , intraventricular haemorrhage 5 , both 3 ) receiving care in the neonatal intensive care unit ( NICU ) at Nagasaki University Hospital . Subjects were r and omly assigned to the EIP  group ( n = 12 ) or the control group  ( n = 11 ) . Participants in the EIP group received a Neonatal Behavioral Assessment scale (NBAS)-based intervention combined with developmental support design ed to enhance the infants ' development and the quality of the parent-infant relationship . The control group received routine medical nursing care without the EIP . The EIP began prior to discharge from the NICU and lasted until 6 months of corrected age . All children were examined on the NBAS preintervention and again at 44 weeks postconceptional age . Maternal anxiety status ( STAI ) and maternal feelings of confidence in dealing with her baby ( LCC ) were measured pre and postintervention . Mental and motor development was assessed postintervention using the Bayley Scale of Infant Development . RESULTS Orientation and State Regulation of infant behavioural profiles , the STAI and LCC scores significantly improved in the EIP group ( mean difference ( 95 % CI ) : Orientation 0.7 ( 0.4 , 1.1 ) , State Regulation 0.9 ( 0.3 , 1.5 ) , STAI -5.5 ( - 9.1 , -1.9 , LCC 5.3 ( 4.2 , 6.5 ) ) , but not in the control group . Bayley mental developmental index ( MDI ) score in the EIP group was higher than in the control group , but there was no significant difference between the two groups ( mean difference ( 95 % CI ) : MDI 8.5 ( - 0.8 , 17.8 ) , PDI 6.7 ( - 1.9 , 15.4 ) ) . CONCLUSION The EIP has beneficial effects on neonatal neurobehavioural development and maternal mental health of low birthweight infants with cerebral injuries . This evidence suggests that short-term changes in maternal mental health and infant neurobehaviour promoted by an EIP may serve to initiate a positive interaction between parents and infants
Conclusion : Positive clinical ly meaningful effects ( > 5 points ) are seen to an age of 36 months , but are no longer present at 5 years
Objective : To determine in a systematic review , whether interventions for infant development that involve parents , improve neurodevelopment at 12 months corrected age or older .