Compared with an energy-restricted SP diet , an isocalorically prescribed HP diet provides modest benefits for reductions in body weight , FM , and triglycerides and for mitigating reductions in FFM and REE
BACKGROUND It is currently unclear whether altering the carbohydrate-to-protein ratio of low-fat , energy-restricted diets augments weight loss and cardiometabolic risk markers .
OBJECTIVE The objective was to conduct a systematic review and meta- analysis of studies that compared energy-restricted , isocaloric , high-protein , low-fat ( HP ) diets with st and ard-protein , low-fat ( SP ) diets on weight loss , body composition , resting energy expenditure ( REE ) , satiety and appetite , and cardiometabolic risk factors .
Effect of a high-protein, energy-restricted diet on weight loss and energy expenditure after weight stabilization in hyperinsulinemic subjects
OBJECTIVE : To determine the effect of replacing some dietary carbohydrate with protein , during energy restriction , on weight loss , total energy expenditure ( TEE ) , resting energy expenditure ( REE ) , respiratory quotient ( RQ ) , and the thermic effect of feeding ( TEF ) in subjects with hyperinsulinemia . DESIGN : Parallel , clinical intervention study of 12 weeks energy restriction ( 6.5 MJ/day ) and 4 weeks energy balance ( 8.2 MJ/day ) in two groups of subjects r and omly assigned to either a high-protein ( HP ) diet ( 27 % of energy ( % E ) as protein , 45%E as carbohydrate ) or a lower-protein ( LP ) diet ( 16%E as protein , 57%E as carbohydrate).SUBJECTS : A total of 36 obese nondiabetic volunteers with hyperinsulinemia ( 10 males/26 females , aged 34–65 y , BMI 28–43 kg/m2 , fasting insulin 12–45 mU/l ) . MEASUREMENTS : Body weight and composition , TEE , REE , and RQ were measured at baseline and at week 16 . In addition , the TEF to an HP or LP meal was determined for 3 h , at baseline and at week 16 . RESULTS : After 16 weeks , weight loss was similar in response to each diet ; the overall decrease was 7.9±0.6 kg ( P<0.001 ) , of which 6.8±0.5 kg was fat ( P<0.001 ) . REE fell similarly with each diet ; the overall decrease was 719±106 kJ/day ( P<0.001 ) . The TEF was 2 % greater after the HP than after the LP meal at baseline ( P<0.01 ) and 0.8 % greater at week 16 ( P=0.35 ) . After 16 weeks , the TEF was not reduced in either dietary group . There was no change in TEE after 16 weeks . CONCLUSION : In subjects with hyperinsulinemia an energy-restrictive diet containing an increased protein-to-carbohydrate ratio does not enhance weight loss or significantly affect energy expenditure . Caloric restriction , rather than the macronutrient composition of the diet , is the most important determinant of weight loss
Compared with an energy-restricted SP diet , an isocalorically prescribed HP diet provides modest benefits for reductions in body weight , FM , and triglycerides and for mitigating reductions in FFM and REE
BACKGROUND It is currently unclear whether altering the carbohydrate-to-protein ratio of low-fat , energy-restricted diets augments weight loss and cardiometabolic risk markers .
OBJECTIVE The objective was to conduct a systematic review and meta- analysis of studies that compared energy-restricted , isocaloric , high-protein , low-fat ( HP ) diets with st and ard-protein , low-fat ( SP ) diets on weight loss , body composition , resting energy expenditure ( REE ) , satiety and appetite , and cardiometabolic risk factors .