There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Effects of long-chain PUFA supplementation in infant formula on cognitive function in later childhood.
BACKGROUND Evidence is accumulating that a dietary supply of long-chain polyunsaturated fatty acids ( LC-PUFAs ) enhances the development of attention and efficient information processing in infants . However , it is uncertain whether LC-PUFAs in infancy influence cognitive development in later childhood . OBJECTIVE The objective was to determine the effects of dietary LC-PUFAs in infancy on measures of cognitive function at age 6 y. DESIGN Infants were r and omly assigned to receive formula containing either docosahexaenoic acid and arachidonic acid or no LCPUFAs for a period of 4 mo . A reference breastfed group was also included . In a follow-up conducted at age 6 y , children received assessment s of intelligence quotient ( IQ ) , attention control ( Day-Night Test ) , and speed of processing on the Matching Familiar Figures Test ( MFFT ) . RESULTS At follow-up there were 71 children in the LC-PUFA group , 76 in the control group , and 88 in the breastfed group . The formula groups did not differ on measures of Full-Scale IQ ( LCPUFA mean = 98.0 ; control mean = 100.9 ) or attention control ( LCPUFA mean = 12.7 ; control mean = 12.8 ) . MFFT error scores were the same for both formula groups , but when making correct responses , the LC-PUFA group was significantly faster ( mean = 6.2 s ) than the control group [ mean = 7.8 s ; F(1 , 131 ) = 6.09 , P = 0.015 ] . CONCLUSIONS IQ scores of children who were fed a formula containing either LC-PUFAs or no LC-PUFAs did not differ at age 6 y. However , children who received LC-PUFAs were faster at processing information compared with children who received unsupplemented formula . Variation in the dietary supply of LC-PUFAs in the first months of life may have long-term consequences for the development of some cognitive functions in later childhood
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .