Weight loss diet beneficially affects blood adiponectin concentrations .
Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass .
However , the magnitude of the effect of low calorie diet on adiponectin concentrations remains unknown .
The present study was aim ed to conduct a systematic review and meta- analysis on clinical trials that access the effect of low calorie diet on adiponectin concentration .
Low‐calorie diet induced weight loss may alter regulatory hormones and contribute to rebound visceral adiposity in obese persons with a family history of type‐2 diabetes
Purpose : To examine potential detrimental long‐term effects of acute diet‐induced weight loss on visceral adiposity , insulin resistance , cortisol , and adipokines in obese individuals at risk for type‐2 diabetes . Data sources : Anthropometric measures ( height , weight , waist circumference ) , self‐report instruments , abdominal computed tomography ( CT ) scan , and blood sample s ( glucose , insulin , interleukin‐6 , leptin , adiponectin ) were obtained from a convenience sample of 20 participants at baseline , after a 28‐day low‐calorie diet ( 800 kcal/day ) intervention , and again 6 months later . Conclusions : Fifteen of 20 participants completed the 28‐day diet intervention and had a mean weight loss of 15 pounds . Comparison between baseline , postdiet , and 6‐month data , demonstrated that although participants had significant improvements after the diet , they regained fat mass , particularly in the visceral area . Implication s for practice : Clinicians may need to revise recommendations for using low‐calorie diets to achieve weight loss . Diet‐induced weight cycling may contribute to dysregulation of metabolism and have long‐term detrimental consequences for accumulation of visceral adipose tissue . The likelihood of success is low , with high dropout rates , and those patients who achieve weight loss are very likely to regain it . Thus , the perceived short‐term benefits of calorie‐restricted diets in this population likely do not outweigh the potential long‐term detrimental effects
Weight loss diet beneficially affects blood adiponectin concentrations .
Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass .
However , the magnitude of the effect of low calorie diet on adiponectin concentrations remains unknown .
The present study was aim ed to conduct a systematic review and meta- analysis on clinical trials that access the effect of low calorie diet on adiponectin concentration .