Based on the existing information , it is not possible to establish the role of antioxidants and vitamin D supplementation in atopic disease development .
There is no evidence of major effects of prenatal use of folic acid on asthma or allergies .
The association of some nutritional interventions with less atopic sensitization seems rather speculative even if such an effect has not been found for some other foods .
The findings indicate rather a balanced and diverse diet without restrictions than a special dietary protocol .
Farming-related exposures may protect against the development of atopic disorders in children .
Long-chain polyunsaturated fatty acids and probiotics seem to be promising c and i date s for allergy prevention .
The paper refers to the recently published empirical data and systematic review s on the impact of diets , foods , nutrients and bioactive substance exposures in pregnancy and in early infancy , on the development of atopic disorders .
Early exposure to solid foods and the development of eczema in children up to 4 years of age.
Early exposure to solid foods in infancy has been associated with the development of allergic diseases . However , scientific evidence for this is conflicting . The aim of this study was to examine the association between early exposure to solid foods in the infant 's diet and the development of  eczema up to 4 years of age . We conducted an etiologic case-control study nested in the PIPO cohort ( Prospect i ve Cohort on the Influence of Perinatal Factors on the Occurrence of Asthma and Allergies ) . In this cohort data on nutrition , environmental exposures and parent-reported eczema were collected prospect ively starting from 5 months pregnancy by means of question naires administered during two home visits and semi-annual postal question naires . In addition , detailed information on the timing of introduction of solid foods at individual food item level was collected at 1 year of age . Adjusted odds ratios and 95 % confidence intervals were computed using logistic regression analysis as a measure of association between eczema and the timing of exposure to solid foods . Early introduction ( within the first 4 months ) of solid foods was inversely associated with eczema up to 4 years of age ( adj OR : 0.49 ; 95 % CI : 0.32 - 0.74 ) . Moreover , we found that early exposure to solid foods was associated with a reduced risk for eczema only among children with allergic parents ( adj OR : 0.35 ; 95 % CI : 0.20 - 0.63 ) , whereas no significant effect was found among children with non-allergic parents ( adj OR : 0.69 ; 95 % CI : 0.37 - 1.29 ) . The results of this study show that early exposure to solid foods is associated with less parent-reported eczema in children , particularly among children with allergic parents . Therefore , the current study does not support a delayed introduction of solid foods for the prevention of  eczema  in childhood
Based on the existing information , it is not possible to establish the role of antioxidants and vitamin D supplementation in atopic disease development .
There is no evidence of major effects of prenatal use of folic acid on asthma or allergies .
The association of some nutritional interventions with less atopic sensitization seems rather speculative even if such an effect has not been found for some other foods .
The findings indicate rather a balanced and diverse diet without restrictions than a special dietary protocol .
Farming-related exposures may protect against the development of atopic disorders in children .
Long-chain polyunsaturated fatty acids and probiotics seem to be promising c and i date s for allergy prevention .
The paper refers to the recently published empirical data and systematic review s on the impact of diets , foods , nutrients and bioactive substance exposures in pregnancy and in early infancy , on the development of atopic disorders .