Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
A controlled study of consumption of beta-glucan-enriched soups for 2 months by type 2 diabetic free-living subjects.
Type 2 diabetes is associated with a higher cardiovascular risk and there has been a growing interest in using dietary intervention to improve lipid profile and glucose control . The present work aims at analysing the effects of the enrichment of a normal diet with beta-glucan ( 3.5 g/d ) in free-living type 2 diabetic subjects for 2 months , using a palatable soup . This trial was a parallel , placebo-controlled , double-blinded r and omised study performed in fifty-three type 2 diabetic subjects . During a 3-week run-in period , subjects daily consumed a ready meal control soup ( without beta-glucan ) . For the following 8 weeks , subjects were r and omly assigned to consume daily either a control soup or a beta-glucan soup .  Changes in lipid profile ( total cholesterol ( TC ) , HDL- and LDL-cholesterol ( HDLc and LDLc ) , apo B and TAG ) and in glucose control ( HbA1c and fasting glucose ) were measured . There was no significant alteration in lipid profile in the two groups ( TC , HDLc , LDLc and apo B ) . TAG decreased significantly in the beta-glucan group compared with the control group ( - 0.12 ( SD 0.38 ) v. 0.12 ( SD 0.44 ) mmol/l , P = 0.03 ) . HbA1c and fasting glucose were not reduced in any group . A single daily ingestion of 3.5 g beta-glucan , as required by official dietary recommendations , for 8 weeks did not change the lipid profile and HbA1c in type 2 diabetic subjects . To improve the metabolic profile of type 2 diabetic subjects in the long term , the quantity , the food vectors and the tolerability of beta-glucan products may be re-evaluated
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .