RESULT ( S ) For infants , studies on psychomotor development showed no deficits , but few investigated cognitive or behavioral development .
Studies on toddlers generally reported normal cognitive , behavioral , socio-emotional , and psychomotor development .
For children in middle childhood , development seems comparable in children born after assisted reproduction and controls , although fewer studies have been conducted with follow-up to this age .
( S ) It may tentatively be concluded that the neurodevelopment of children born after  fertility treatment  is overall comparable to that in children born after spontaneous conception
OBJECTIVE To systematic ally review the existing literature on neurodevelopmental outcomes in children born after medically assisted reproduction  compared with those of children born after spontaneous conception .
Health of children born after ovulation induction.
OBJECTIVE To study the health of children born after ovulation induction ( OI ) . DESIGN Nationwide register-based study . SETTING The OI children were followed up to the age of 4 years and compared with other children . PATIENT(S ) The OI children ( N = 4,467 ) . Two control groups : all other children ( excluding children born after IVF , N = 190,398 ) and a r and om sample of those children ( n = 26,877 ) . INTERVENTION(S ) Ovulation induction treatment in ordinary practice . MAIN OUTCOME MEASURE(S ) Mortality rates and adjusted odds ratios for perinatal outcomes , hospitalizations , health-related benefits , and long-term medication use . RESULT ( S ) A total of 12 % of OI and 2 % of control children were multiples . Even after stratifying for multiplicity and adjusting for the available confounding factors ( region , smoking , maternal age , socioeconomic position , and parity for perinatal health and mother 's socioeconomic position for other indicators ) , most indicators showed worse health among OI children compared with control children . The OI children had poorer perinatal health and more episodes of long hospitalization than the control children . Singleton OI children had more long-term illnesses in childhood , as measured by child disability allowance , long-term medication use , and hospital care episodes . CONCLUSION ( S ) Either OI treatment or the reasons for the treatment increase the risk of health problems in early childhood
RESULT ( S ) For infants , studies on psychomotor development showed no deficits , but few investigated cognitive or behavioral development .
Studies on toddlers generally reported normal cognitive , behavioral , socio-emotional , and psychomotor development .
For children in middle childhood , development seems comparable in children born after assisted reproduction and controls , although fewer studies have been conducted with follow-up to this age .
( S ) It may tentatively be concluded that the neurodevelopment of children born after  fertility treatment  is overall comparable to that in children born after spontaneous conception
OBJECTIVE To systematic ally review the existing literature on neurodevelopmental outcomes in children born after medically assisted reproduction  compared with those of children born after spontaneous conception .