The results do not provide sufficient evidence for or against recommending probiotics for the treatment of BV .
BACKGROUND The dominance of lactobacilli in healthy vaginal microbiota and its depletion in bacterial vaginosis ( BV ) has given rise to the concept of oral or vaginal instillation of probiotic Lactobacillus strains for the management of this condition .
OBJECTIVES To ascertain the efficacy of probiotics in the treatment of BV .
Women's satisfaction with an intravaginal Lactobacillus capsule for the treatment of bacterial vaginosis.
OBJECTIVE To assess women 's satisfaction with a vaginal capsule containing human-derived , H(2)O(2)-producing Lactobacillus crispatus at completion of a r and omized , placebo-controlled study for treatment of bacterial vaginosis ( BV ) . METHODS Women aged 14 - 35 years with BV were r and omized  to Lactobacillus or placebo intravaginal capsule twice daily for 3 days monthly for 3 months . Attitudes were assessed with a st and ardized scale at the final follow-up visit , and associations of satisfaction with clinical and gram stain cure of BV were determined . RESULTS Four hundred twenty-four women were r and omized at enrollment , and 232 ( 55 % ) provided data on satisfaction at the final visit . Overall , satisfaction with the capsule was high and was independent of subjects ' race , age , and prior history of BV . Report of satisfaction with the capsule , belief that it contained healthy bacteria , and belief that its use improved vaginal health were directly related to clinical cure and to improved Nugent score . Except for women who had BV at the final follow-up visit , most subjects believed that the capsule contained healthy bacteria independent of any outcome reflecting cure . Willingness to use the capsule again was not significantly related to whether subjects experienced clinical cure or normalization of Nugent score at either visit . Adverse effects were rare and were largely related to a perceived difference in vaginal discharge . CONCLUSIONS Satisfaction with an intravaginal capsule and positive beliefs about its use for BV treatment were prevalent , especially among women with a clinical and microbiological response to BV therapy . However , most women expressed willingness to use the product again regardless of clinical response . Acceptability of and interest in alternative BV treatments , such as L. crispatus intravaginal applications , are high
The results do not provide sufficient evidence for or against recommending probiotics for the treatment of BV .
BACKGROUND The dominance of lactobacilli in healthy vaginal microbiota and its depletion in bacterial vaginosis ( BV ) has given rise to the concept of oral or vaginal instillation of probiotic Lactobacillus strains for the management of this condition .
OBJECTIVES To ascertain the efficacy of probiotics in the treatment of BV .