A well-implemented ERAS protocol with good compliance is associated with a reduction in medical complications and length of hospital stay .
Enhanced recovery after surgery ( ERAS ) pathways are now implemented worldwide with strong evidence that adhesion to such protocol reduces medical complications , costs and hospital stay .
This concept has been applied for pancreatic surgery since the first published guidelines in 2012 .
This study presents the up date d ERAS recommendations for  pancreatoduodenectomy ( PD )  based on the best available evidence and on expert consensus .
Efficacy of octreotide in the prevention of complications after pancreaticoduodenectomy in patients with soft pancreas and non-dilated pancreatic duct: A prospective randomized trial.
BACKGROUND The efficacy of octreotide to prevent postoperative pancreatic fistula ( POPF ) of pancreaticoduodenectomy ( PD ) is still controversial . This study aim ed to evaluate the effect of postoperative use of octreotide on the outcomes after PD . METHODS This is a prospect i ve r and omized controlled trial for postoperative use of octreotide in patients undergoing PD . Patients with soft pancreas and pancreatic duct < 3 mm were r and omized to 2 groups . Group I did not receive postoperative octreotide . Group II received postoperative octreotide . The primary end of the study is to compare the rate of POPF . RESULTS A total of 104 patients were included in the study and were divided into two r and omized groups . There were no significant difference in overall complications and its severity . POPF occurred in 11 patients ( 21.2 % ) in group I and 10 ( 19.2 % ) in group II , without statistical significance ( P = 0.807 ) . Also , there was no significant differences between both groups regarding the incidence of biliary leakage ( P = 0.083 ) , delayed gastric emptying ( P = 0.472 ) , and early postoperative mortality ( P = 0.727 ) . CONCLUSIONS Octreotide did not reduce postoperative morbidities , reoperation and mortality rate . Also , it did not affect the incidence of POPF and its clinical ly relevant variants
A well-implemented ERAS protocol with good compliance is associated with a reduction in medical complications and length of hospital stay .
Enhanced recovery after surgery ( ERAS ) pathways are now implemented worldwide with strong evidence that adhesion to such protocol reduces medical complications , costs and hospital stay .
This concept has been applied for pancreatic surgery since the first published guidelines in 2012 .
This study presents the up date d ERAS recommendations for  pancreatoduodenectomy ( PD )  based on the best available evidence and on expert consensus .