REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .
[The effect of nimodipine on retinal blood flow in pregnancy induced hypertension].
OBJECTIVE To assess the effects of nimodipine on retinal blood flow in patients with pregnancy induced hypertension ( PIH ) . METHODS Fourteen patients were studied with color flow Doppler before and after 30 mg nimodipine administered orally , while other fourteen patients received intravenous magnesium sulfate as control group .  Central retinal artery flow velocity waveforms were measured and pulse index ( PI ) were calculated . RESULTS Nimodipine reduced the central retinal artery PI significantly from 0.92 + /- 0.14 to 0.75 + /- 0.22 . It also reduced systolic blood pressure from 20.7 + /- 2.5 kPa to 19.8 + /- 1.5 kPa and diastolic blood pressure from 14.4 + /- 2.3 kPa to 13.6 + /- 1.9 kPa . CONCLUSIONS Nimodipine may dilate central retinal arteries . Changes in pulsatility index in retinal arteries maybe indicative of similar changes in other cerebral vessels . Nimodipine may be another choice of PIH therapy
REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .