Changes in FOX did not reach the level of statistical significance .
Finding showed that EGCG intake moderately accelerates EE and reduces RQ .
The analyses revealed that the EGCG result ed in difference in RQ and EE but the effect on the other measures of energy metabolism was relatively mild .
Possibly , EGCG alone has the potential to increase metabolic rate at 300 mg dose .
Collectively , the outcome supports the findings that EGCG has an effect on metabolic parameters .
Green tea catechins ( GTCs ) are known to improve fat oxidation ( FOX ) during fasted , rested and exercise conditions wherein epigallocatechin-3-gallate ( EGCG ) is thought to be the most pharmacologically active and has been studied extensively .
From the available data of r and omized controlled trials ( RCTs ) on EGCG , we carried out a systematic review and meta- analysis to eluci date whether EGCG consumption indeed increase energy expenditure ( EE ) and promote FOX .
Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial.
BACKGROUND Tea consumption has been associated with decreased cardiovascular risk , but potential mechanisms of benefit are ill-defined . While epidemiologic studies suggest that drinking multiple cups of tea per day lowers low-density lipoprotein cholesterol ( LDL-C ) , previous trials of tea drinking and administration of green tea extract have failed to show any impact on lipids and lipoproteins in humans . Our objective was to study the impact of a theaflavin-enriched green tea extract on the lipids and lipoproteins of subjects with mild to moderate hypercholesterolemia . METHODS Double-blind , r and omized , placebo-controlled , parallel-group trial set in outpatient clinics in 6 urban hospitals in China . A total of 240 men and women 18 years or older on a low-fat diet with mild to moderate hypercholesterolemia were r and omly assigned to receive a daily capsule containing theaflavin-enriched green tea extract ( 375 mg ) or placebo for 12 weeks . Main outcome measures were mean percentage changes in total cholesterol , LDL-C , high-density lipoprotein cholesterol ( HDL-C ) , and triglyceride levels compared with baseline . RESULTS After 12 weeks , the mean + /- SEM changes from baseline in total cholesterol , LDL-C , HDL-C , and triglyceride levels were -11.3 % + /- 0.9 % ( P = .01 ) , -16.4 % + /- 1.1 % ( P = .01 ) , 2.3 % + /- 2.1 % ( P = .27 ) , and 2.6 % + /- 3.5 % ( P = .47 ) , respectively , in the tea extract group . The mean levels of total cholesterol , LDL-C , HDL-C , and triglycerides did not change significantly in the placebo group . No significant adverse events were observed . CONCLUSION The theaflavin-enriched green tea extract we studied is an effective adjunct to a low-saturated-fat diet to reduce LDL-C in hypercholesterolemic adults and is well tolerated
Changes in FOX did not reach the level of statistical significance .
Finding showed that EGCG intake moderately accelerates EE and reduces RQ .
The analyses revealed that the EGCG result ed in difference in RQ and EE but the effect on the other measures of energy metabolism was relatively mild .
Possibly , EGCG alone has the potential to increase metabolic rate at 300 mg dose .
Collectively , the outcome supports the findings that EGCG has an effect on metabolic parameters .
Green tea catechins ( GTCs ) are known to improve fat oxidation ( FOX ) during fasted , rested and exercise conditions wherein epigallocatechin-3-gallate ( EGCG ) is thought to be the most pharmacologically active and has been studied extensively .
From the available data of r and omized controlled trials ( RCTs ) on EGCG , we carried out a systematic review and meta- analysis to eluci date whether EGCG consumption indeed increase energy expenditure ( EE ) and promote FOX .