None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .
[Effect of intensive insulin therapy on the clinical results of postoperative patients with gastric cancer].
OBJECTIVE To investigate the influence of intensive insulin therapy on the results of postoperative patients with gastric cancer . METHODS Forty-six patients with gastric cancer underwent radical operation were r and omly divided into two groups : intensive group ( n=23 , to control blood glucose at 4.4 to 6.1 mmol/L ) and conventional group ( n=23 , to control blood glucose at 10.0 to 11.1 mmol/L ) .  Fasting blood glucose ( FBG ) , fasting insulin ( FINS ) , tumor necrosis factor-alpha ( TNF-alpha ) , interleukin-6 ( IL-6 ) and C reaction protein ( CRP ) in 46 patients were detected dynamically during perioperative period . Insulin resistance index ( HOMA-IR ) were calculated using Homeostasis Model Assessment ( HOMA ) to evaluate insulin sensitivity . Postoperative complications and other clinical data were recorded . RESULTS No hypoglycemia occurred in the two groups . Compared with conventional group , morbidity and postoperative duration of fever , antibiotic use and the length of hospital stay in intensive group were significantly reduced ( P < 0.05 ) . On the day 1 and 3 after surgery , HOMA-IR and serum levels of TNF-alpha , IL-6 and CRP in patients of intensive group were significantly lower than those in conventional group ( P < 0.05 ) . CONCLUSIONS Intensive insulin therapy could counteract the state of high-inflammation and then improve the outcome of postoperative patients
None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .