In regards to surgery it is recommended to perform total omentectomy since subclinic metastasis have been documented in 10 - 30 % of all cases , and systematic limphadenectomy , necessary to be able to obtain an adequate surgical staging .
Minimal invasion surgery is not a recommended procedure for the treatment of advanced ovarian cancer .
Radiotherapy can be used to palliate symptoms .
In the present , there is not a st and ardized screening method .
Diagnosis in early stages means a better survival .
Radiotherapy can be indicated to palliate symptoms
INTRODUCTION Ovarian cancer ( OC ) is the third most common gynecologic malignancy worldwide .
Most of cases it is of epithelial origin .
At the present time there is not a st and ardized screening method , which makes difficult the early diagnosis .
The 5-year survival is 90 % for early stages , however most cases present at advanced stages , which have a 5-year survival of only 5 - 20 % .
GICOM collaborative group , under the auspice of different institutions , have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia .
Until now , laparoscopy for diagnostic-staging surgery is not well known as a recommended method .
In advanced stages , primary cytoreduction is recommended as initial treatment .
Secondary cytoreduction plus oxaliplatin-based HIPEC in platinum-sensitive recurrent ovarian cancer patients: a pilot study.
OBJECTIVES To assess feasibility , complications and efficacy of secondary surgical cytoreduction ( CRS ) and hyperthermic intraperitoneal chemotherapy ( HIPEC ) in a selected group of platinum-sensitive recurrent ovarian cancer patients . METHODS Recurrent ovarian cancer patients with a platinum-free interval of at least 6 months were prospect ively enrolled . After complete CRS they were su bmi tted to intraperitoneal perfusion of oxaplatinum ( 460 mg/m(2 ) ) heated to 41.5 degrees C for 30 min . Then they received systemic chemotherapy with taxotere 75 mg/m(2 ) and oxaliplatin 100 mg/m(2 ) for 6 cycles . Patients were followed up routinely until recurrence or death . RESULTS Twenty-five recurrent ovarian cancer patients were valuable for the study . The median Platinum Free Interval ( PFI ) was 25 months ( range 7 - 67 ) . The majority of the patients ( 76 % ) had diffuse carcinosis . Nobody had ascites . An optimal residual disease was obtained in all patients . The median duration of CRS+HIPEC  was 312 min ( range 138 - 619 ) . Median intensive care unit ( ICU ) stay was 2 days ( 1 - 6 ) , median hospital stay was 13 days ( 7 - 30 ) . Post-operative major complications were observed in 7 patients ( 28 % ) . Post-operative mortality was 0 % . With a median follow-up time of 18 months ( range 3 - 38 ) , 24 patients ( 96 % ) are alive , but seven women ( 28 % ) have relapsed . CONCLUSIONS Adequate pre-operative selection can improve feasibility of CRS and HIPEC .  Morbidity rate is comparable to aggressive cytoreduction without HIPEC . Although associated with some post-operative morbidity , long-term results are encouraging , waiting for larger series and longer follow-up data
In regards to surgery it is recommended to perform total omentectomy since subclinic metastasis have been documented in 10 - 30 % of all cases , and systematic limphadenectomy , necessary to be able to obtain an adequate surgical staging .
Minimal invasion surgery is not a recommended procedure for the treatment of advanced ovarian cancer .
Radiotherapy can be used to palliate symptoms .
In the present , there is not a st and ardized screening method .
Diagnosis in early stages means a better survival .
Radiotherapy can be indicated to palliate symptoms
INTRODUCTION Ovarian cancer ( OC ) is the third most common gynecologic malignancy worldwide .
Most of cases it is of epithelial origin .
At the present time there is not a st and ardized screening method , which makes difficult the early diagnosis .
The 5-year survival is 90 % for early stages , however most cases present at advanced stages , which have a 5-year survival of only 5 - 20 % .
GICOM collaborative group , under the auspice of different institutions , have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia .
Until now , laparoscopy for diagnostic-staging surgery is not well known as a recommended method .
In advanced stages , primary cytoreduction is recommended as initial treatment .