There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Neurodevelopmental Quotient of Healthy Term Infants at 4 Months and Feeding Practice: The Role of Long-Chain Polyunsaturated Fatty Acids
ABSTRACT : A direct influence of dietary long-chain polyunsaturated fatty acids ( LC-PUFA ) on the developmental quotient ( DQ ) of the healthy term infant remains unexplored . To test this hypothesis , we design ed a prospect i ve study of three types of diet . Twentynine infants received a LC-PUFA-supplemented formula , 31 received a st and ard infant formula , and 30 infants were breastfed exclusively .  Neurodevelopmental response was measured by the Brunet-Lézine psychomotor development lest at 4 mo . The fatty acid status was also assessed among three diet subgroups ( 59 subjects ) at 4 mo . Formula-fed infants who received LC-PUFA supplementation scored significantly higher ( p < 0.01 ) on the Brunet-Lézine scale than infants who received the st and ard formula . Breast-fed infants also performed better than those fed the st and ard formula . Arachidonic acid and docosahexaenoic acid levels in circulating lipids and erythrocyte phospholipids were higher among breast-fed infants and among the group fed the arachidonic- and docosahexaenoic acid-supplemented formula . These findings are suggestive that formula supplementation with one or both of these fatty acids can benefit term infants in neurodevelopmental performance
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .