There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Breast milk fatty acid profile in relation to infant growth and body composition: results from the INFAT study
Background : There is some evidence that the n-6/n-3 long-chain polyunsaturated fatty acids ( LCPUFAs ) ratio in early nutrition , and thus in breast milk , could influence infant body composition . Methods : In an open-label r and omized controlled trial ( RCT ) , 208 healthy pregnant women were allocated to a dietary intervention ( supplementation with 1,200 mg n-3 LCPUFAs per day and instructions to reduce arachidonic acid ( AA ) intake ) from the 15th wk of gestation until 4 mo of lactation or to follow their habitual diet . Breast milk LCPUFAs at 6 wk and 4 mo postpartum were related to infant body composition assessed by skinfold thickness ( SFT ) measurements and ultrasonography during the first year of life . Results : Dietary intervention significantly reduced breast milk n-6/n-3 LCPUFAs ratio . In the whole sample , early breast milk docosahexaenoic acid ( DHA ) , eicosapentaenoic acid ( EPA ) , and n-3 LCPUFAs at 6 wk postpartum were positively related to the sum of four SFT measurements at age 1 . Breast milk AA and n-6 LCPUFAs at 6 wk postpartum were negatively associated with weight , BMI , and lean body mass ( LBM ) up to 4 mo postpartum . Conclusion : Breast milk n-3 LCPUFAs appear to stimulate fat mass growth over the first year of life , whereas AA seems to be involved in the regulation of overall growth , especially in the early postpartum period
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .