Cognitive behavioral therapy may reduce relapse risk for adults with AN after weight restoration , although its efficacy in the underweight state remains unknown .
Variants of family therapy are efficacious in adolescents , but not in adults .
Evidence for AN treatment is weak ; evidence for treatment-related harms and factors associated with efficacy of treatment are weak ; and evidence for differential outcome by sociodemographic factors is nonexistent .
OBJECTIVE The RTI International-University of North Carolina at Chapel Hill Evidence -based Practice Center ( RTI-UNC EPC ) systematic ally review ed evidence on efficacy of treatment for anorexia nervosa ( AN ) , harms associated with treatments , factors associated with treatment efficacy , and differential outcome by sociodemographic characteristics .
A single blind comparison of amisulpride, fluoxetine and clomipramine in the treatment of restricting anorectics
1 . The study evaluated the efficacy of amisulpride , fluoxetine and clomipramine at the beginning of the re-feeding phase of the treatment of restricting anorexia nervosa according to DSM-IV criteria . 2 . 13 patients , mean weight 37.61 kg + /- 9.80 SD , were treated with clomipramine at a mean dosage of 57.69 mg + /- 25.79 SD ; 10 patients , mean weight 40.90 kg + /- 6.98 SD , were treated with fluoxetine at a mean dosage of 28.00 mg + /- 10.32 SD ; 12 patients , mean weight 38.41 kg + /- 8.33 SD , were treated with amisulpride at a mean dosage of 50.00 mg + /- 0.00 SD . 3 . Clinical evaluation was carried out under single-blind condition at basal time and after three months by a structured clinical interview , the Eating Disorder Interview based on Long Interval Follow-up Evaluation ( LIFE II BEI ) . 4 . Patients treated with amisulpride showed a more significant increase ( p=0.016 ) of mean weight . Concerning weight phobia , body image disturbance and amenorrhoea , no significant difference result ed
Cognitive behavioral therapy may reduce relapse risk for adults with AN after weight restoration , although its efficacy in the underweight state remains unknown .
Variants of family therapy are efficacious in adolescents , but not in adults .
Evidence for AN treatment is weak ; evidence for treatment-related harms and factors associated with efficacy of treatment are weak ; and evidence for differential outcome by sociodemographic factors is nonexistent .
OBJECTIVE The RTI International-University of North Carolina at Chapel Hill Evidence -based Practice Center ( RTI-UNC EPC ) systematic ally review ed evidence on efficacy of treatment for anorexia nervosa ( AN ) , harms associated with treatments , factors associated with treatment efficacy , and differential outcome by sociodemographic characteristics .