In this sub-set , it was found that method ological differences contributed to variation in utility values .
Direct methods often yielded higher scores than did indirect methods .
Within direct methods , there were no clear trends in head-to-head studies ( st and ard gamble [ SG ] vs time trade-off ) ; but general population respondents often provided lower scores than did patients with the disease when evaluating the same health states with SG methods .
When comparing indirect methods , the EQ-5D typically yielded higher values than the SF-6D , but also showed more sensitivity to differences in health states .
When selecting CVD utility values for an economic model , consideration of the utility elicitation method is important , as this review demonstrates that methodology of choice impacts utility values in CVD
AIMS Utility values inform estimates of the cost-effectiveness of treatment for cardiovascular disease ( CVD ) , but values can vary depending on the method used .
The aim of this systematic literature review ( SLR ) was to explore how methods of elicitation impact utility values for CVD .
Agreement about Identifying Patients Who Change over Time
Background . Preference-based measures of health-related quality of life all use the same dead = 0.00 to perfect health = 1.00 scale , but there are substantial differences among measures . Objective . The objective was to examine agreement in classifying patients as better , stable , or worse . Methods . The EQ-5D , Health Utilities Index Mark 2 and Mark 3 , Quality of Well-Being – Self-Administered scale , Short-Form 36 ( Short-Form 6D ) , and disease-targeted measures were administered prospect ively in 2 clinical cohorts . The study was conducted at academic medical centers : University of California , Los Angeles ; University of California , San Diego ; University of Wisconsin – Madison ; and University of Southern California . Patients undergoing cataract extraction surgery with lens replacement completed the 25-item National Eye Institute Visual Function Question naire ( NEI-VFQ-25 ) .  Patients newly referred to congestive heart failure specialty clinics completed the Minnesota Living with Heart Failure Question naire ( MLHF ) . In both cohorts , subjects completed surveys at baseline and at 1 and 6 months . The NEI-VFQ-25 and MLHF were used as gold st and ards to assign patients to categories of change . Agreement was assessed using κ . Results . There were 376 cataract patients recruited . Complete data for baseline and the 1-month follow-up were available on all measures for 210 cases . Using criteria specified by Altman , agreement was poor for 6 of 9 pairs of comparisons and fair for 3 pairs . There were 160 heart failure patients recruited . Complete data for baseline and the 6-month follow-up were available for 86 cases . Agreement was negligible for 5 pairs and fair for 1 . The study was conducted on selected patients at a few academic medical centers . Conclusions . The results underscore the lack of interchangeability among different preference-based measures
In this sub-set , it was found that method ological differences contributed to variation in utility values .
Direct methods often yielded higher scores than did indirect methods .
Within direct methods , there were no clear trends in head-to-head studies ( st and ard gamble [ SG ] vs time trade-off ) ; but general population respondents often provided lower scores than did patients with the disease when evaluating the same health states with SG methods .
When comparing indirect methods , the EQ-5D typically yielded higher values than the SF-6D , but also showed more sensitivity to differences in health states .
When selecting CVD utility values for an economic model , consideration of the utility elicitation method is important , as this review demonstrates that methodology of choice impacts utility values in CVD
AIMS Utility values inform estimates of the cost-effectiveness of treatment for cardiovascular disease ( CVD ) , but values can vary depending on the method used .
The aim of this systematic literature review ( SLR ) was to explore how methods of elicitation impact utility values for CVD .