Adherence to DASH diet is effective in improving circulating serum inflammatory biomarkers in adults , compared with usual diet ; therefore , it could be a valuable strategy to suppress inflammation process
BACKGROUND & AIMS Dietary approaches to stop hypertension ( DASH ) diet is associated with improved blood pressure and risk of cardiovascular diseases .
It is proposed that DASH might also improve systemic inflammatory markers like highly sensitive C-reactive protein ( hs-CRP ) ; however , interventional studies have led to conflicting results .
The aim of current systematic review was to summarize results of r and omized clinical trials examining the effect of DASH on inflammatory biomarkers .
Beef in an Optimal Lean Diet study: effects on lipids, lipoproteins, and apolipoproteins123
Background : A Step I diet with lean beef compared with lean white meat both decrease  LDL cholesterol .  To our knowledge , no studies have evaluated a low – saturated fatty acid ( SFA ) ( < 7 % calories ) diet that contains lean beef . Objective : We studied the effect on LDL cholesterol of cholesterol-lowering diets with varying amounts of lean beef [ ie , Dietary Approaches to Stop Hypertension ( DASH ) : 28 g beef/d ; Beef in an Optimal Lean Diet ( BOLD ) : 113 g beef/d ; and Beef in an Optimal Lean Diet plus additional protein ( BOLD+ ) : 153 g beef/d ] compared with that of a healthy American diet ( HAD ) . Design : Thirty-six hypercholesterolemic participants ( with LDL-cholesterol concentrations > 2.8 mmol/L ) were r and omly assigned to consume each of the 4 diets ( HAD : 33 % total fat , 12 % SFA , 17 % protein , and 20 g beef/d ) , DASH ( 27 % total fat , 6 % SFA , 18 % protein , and 28 g beef/d ) , BOLD ( 28 % total fat , 6 % SFA , 19 % protein , and 113 g beef/d ) , and BOLD+ ( 28 % total fat , 6 % SFA , 27 % protein , and 153 g beef/d ) for 5 wk . Results : There was a decrease in total cholesterol ( TC ) and LDL-cholesterol concentrations ( P < 0.05 ) after consumption of the DASH ( −0.49 ± 0.11 and −0.37 ± 0.09 mmol/L , respectively ) , BOLD ( −0.48 ± 0.10 and −0.35 ± 0.9 mmol/L , respectively ) , and BOLD+ ( −0.50 ± 0.10 and −0.345 ± 0.09 mmol/L , respectively ) diets compared with after consumption of the HAD ( −0.22 ± 0.10 and −0.14 ± 0.10 mmol/L , respectively ) . Apolipoprotein A-I , C-III , and C-III bound to apolipoprotein A1 particles decreased after BOLD and BOLD+ diets compared with after the HAD , and there was a greater decrease in apolipoprotein B after consumption of the BOLD+ diet than after consumption of the HAD ( P < 0.05 for both ) . LDL cholesterol and TC decreased after consumption of the DASH , BOLD , and BOLD+ diets when the baseline C-reactive protein ( CRP ) concentration was < 1 mg/L ; LDL cholesterol and TC decreased when baseline CRP concentration was > 1 mg/L with the BOLD and BOLD+ diets . Conclusions : Low-SFA , heart-healthy dietary patterns that contain lean beef elicit favorable effects on cardiovascular disease ( CVD ) lipid and lipoprotein risk factors that are comparable to those elicited by a DASH dietary pattern . These results , in conjunction with the beneficial effects on apolipoprotein CVD risk factors after consumption of the BOLD and BOLD+ diets , which were greater with the BOLD+ diet , provide support for including lean beef in a heart-healthy dietary pattern . This trial was registered at clinical trials.gov as NCT00937898
Adherence to DASH diet is effective in improving circulating serum inflammatory biomarkers in adults , compared with usual diet ; therefore , it could be a valuable strategy to suppress inflammation process
BACKGROUND & AIMS Dietary approaches to stop hypertension ( DASH ) diet is associated with improved blood pressure and risk of cardiovascular diseases .
It is proposed that DASH might also improve systemic inflammatory markers like highly sensitive C-reactive protein ( hs-CRP ) ; however , interventional studies have led to conflicting results .
The aim of current systematic review was to summarize results of r and omized clinical trials examining the effect of DASH on inflammatory biomarkers .