Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .
Effect of garlic on thrombocyte aggregation, microcirculation, and other risk factors.
Significant positive effects could be achieved in a placebo-controlled double-blind study through the administration of 800 mg of garlic powder over a period of four weeks . Spontaneous thrombocyte aggregation disappeared , the microcirculation of the skin increased by 47.6 % ( from 0.63 + /- 0.13 to 0.93 + /- 0.22 mm/s ) , plasma viscosity decreased by 3.2 % ( from 1.25 + /- 0.34 to 1.21 + /- 0.43 mPas ) , diastolic blood pressure by 9.5 % ( from 74 + /- 9 to 67 + /- 5 mmHg ) , and blood glucose concentration by 11.6 % ( from 89.4 + /- 8.8 to 79.0 + /- 11.9 mg/dl ) . The vascular protection of garlic as atherosclerosis prevention by influencing the mentioned risk parameters for cardiovascular diseases must be pointed out . Especially interesting is the thrombocyte aggregation inhibiting effect . Thus , the application of garlic may be useful in case of acetylsalicyclic acid intolerance
Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .