Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .
Food and drug reactions, wheezing, and eczema in preterm infants.
Allergic reactions were investigated in 777 preterm infants who were r and omly assigned to early diet and followed up to 18 months post term .  Wheezing or asthma was common ( incidence 23 % ) ; it was associated with neonatal ventilation , maternal smoking , and a family history of atopy and was unexpectedly reduced in babies born by caesarean section . Even in non-ventilated infants , the incidence of subsequent wheezing was 18 % , rising to an estimated 44 % ( using logistic regression ) when the foregoing risk factors ( excluding ventilation ) were present .  Eczema occurred in 151 infants ( 19 % ) and was strongly associated with  multiple pregnancy  ( 30 % incidence in twins or triplets ) . Reactions to cows ' milk ( incidence : 4.4 % from detailed history ; 0.8 % confirmed by challenge ) , other foods ( 10 % ) , and drugs ( 5 % ) were within the range reported in full term infants . Milk and food reactions were associated with multiple pregnancy ( 19 % ) and a family history of atopy . Reactions to drugs were least likely to occur in infants who had been ventilated and were on multiple medications in the neonatal period , suggesting that drug tolerance may have developed . We speculate that preterm infants may be a high risk group for asthma and eczema , which could imply an association between atopy and prematurity
Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .