Conclusions HbA1c is neither sensitive nor specific for detecting pre‐diabetes ; fasting glucose is specific but not sensitive .
Interventions in people classified through screening as having pre‐diabetes have some efficacy in preventing or delaying onset of type 2 diabetes in trial population s. As screening is inaccurate , many people will receives an incorrect diagnosis and be referred on for interventions while others will be falsely reassured and not offered the intervention .
These findings suggest that “ screen and treat ” policies alone are unlikely to have substantial impact on the worsening epidemic of type 2 diabetes .
& NA ; Objectives To assess diagnostic accuracy of screening tests for  pre‐diabetes  and efficacy of interventions ( lifestyle or metformin ) in preventing onset of type 2 diabetes in people with pre‐diabetes .
Short-term effectiveness of an individual counseling program for impaired fasting glucose and mild type 2 diabetes in Japan: a multi-center randomized control trial.
The aim of this study is to evaluate the short-term effectiveness of our individual-based counseling program and tools among individuals in ordinary Japanese communities with impaired fasting glucose ( IFG ) and mild type 2 diabetes . A total of 233 eligible participants ( age 30 - 69 years ) in 14 local study centers were r and omly assigned to an intervention group ( INT , N=119 ) and a control group ( CONT , N=114 ) . During the 4-month intervention , the INT received 4 individual counseling sessions and one reminder on life style modification . The CONT received only an explanation of blood test results and general information on diabetes . Baseline characteristics did not differ significantly between groups . Percentages of participants with desirable changes in glycemic level and weight were significantly higher in INT than CONT : fasting plasma glucose reduction of more than 10 mg/dL ( 39 % in INT vs. 26 % in CONT , p=0.045 ) , hemoglobinA1c reduction greater than 0.3 % ( 14 % vs. 4 % , p=0.01 ) , and weight reduction of more than 4 kg ( 13 % vs. 4 % , p=0.025 ) . Decreases in total energy intake and percentage of heavy alcohol drinkers ( more than 46 g/day ) were significantly greater in INT than CONT . The increase in percentages of participants who engaged in leisure time physical activity more than 12 times per month was significantly greater in INT than CONT . Our program result ed in life style modification and glycemic level improvement in the short-term among individuals with IFG and mild type 2 diabetes . Results indicated that the program was sufficiently effective and feasible for implementation in ordinary communities
Conclusions HbA1c is neither sensitive nor specific for detecting pre‐diabetes ; fasting glucose is specific but not sensitive .
Interventions in people classified through screening as having pre‐diabetes have some efficacy in preventing or delaying onset of type 2 diabetes in trial population s. As screening is inaccurate , many people will receives an incorrect diagnosis and be referred on for interventions while others will be falsely reassured and not offered the intervention .
These findings suggest that “ screen and treat ” policies alone are unlikely to have substantial impact on the worsening epidemic of type 2 diabetes .
& NA ; Objectives To assess diagnostic accuracy of screening tests for  pre‐diabetes  and efficacy of interventions ( lifestyle or metformin ) in preventing onset of type 2 diabetes in people with pre‐diabetes .