In conclusion , statins were effective in preventing postoperative adhesion , as assessed based on gross and microscopic adhesion scores in rats
Adhesion is a significant concern after surgery .
Many research ers studied the anti-adhesive effect of statin , of which results were inconsistent .
Thus , we purpose d to perform a systematic review and meta- analysis to evaluate the effect of statins on postoperative adhesion in an experimental study .
AbobotulinumtoxinA: A New Therapy for Hip Osteoarthritis. A Prospective Randomized Double-Blind Multicenter Study
Hip Osteoarthritis ( OA ) causes pain and disability . Here we evaluate abobotulinumtoxinA ( Dysport ® ) ( AboBoNT-A ) injections versus placebo as a novel treatment option to improve hip range of motion , pain and quality of life . This prospect i ve r and omized double-blind multicenter study ( EudraCT # 2012 - 004890 - 25 ) recruited 46 out patients with hip OA who were r and omized 2:1 to the Treatment Group ( TG ; 31 subjects ) , or the Placebo Group ( PG ; 15 subjects ) . The TG received 400 U of AboBoNT-A injected into the adductor muscles , and the PG received placebo solution . The primary endpoints were the difference in Harris Hip Score ( HHS ) and Visual Analogic Scale for pain ( VAS ) at Week 4 between groups ( TG vs. PG ) . Secondary endpoints were the change from baseline in HHS , VAS pain , Medical Research Council scale for muscle strength ( MRC ) and Short Form scale ( SF-36 ) scores . In TG at Week 4 , the HHS and VAS score were significantly improved compared to PG , and pairwise assessment s showed significant improvements in HSS and VAS pain at each time point compared to baseline for TG . No significant changes were observed in MRC and SF-36 over time , though SF-36 showed a positive trend . There were no significant differences from baseline in the PG . No adverse events were detected in either treatment group . AboBoNT-A injections in hip OA improve range of motion and pain without any significant side effects
In conclusion , statins were effective in preventing postoperative adhesion , as assessed based on gross and microscopic adhesion scores in rats
Adhesion is a significant concern after surgery .
Many research ers studied the anti-adhesive effect of statin , of which results were inconsistent .
Thus , we purpose d to perform a systematic review and meta- analysis to evaluate the effect of statins on postoperative adhesion in an experimental study .