Both journals are anchored in large scientific societies and serve basically the same medical , physical and biological community and at the same scientific level ; the two journals are in the most recent Impact Factor list ranked almost back to back , indicating an equal importance and contribution to science .
Radiotherapy and Oncology is more than a scientific journal , it also serves other purpose s such as facilitate education through ( educational ) review s and improving the st and ard of care by bringing forward guidelines for conduct of radiotherapy .
Finally , the journal also tries to maintain a communication platform between the science produced by the membership of ESTRO and therefore it brings papers frommembers in the different European countries , sometimes at the expense of ultimate scientific quality , but with the underst and ing that it is important that the entire ESTRO membership gets access and opportunity to publish in a high ranked journal .
ESTRO , the European Society for Therapeutic Radiation Oncology , or with its new name European Society for Radiation Oncology , is a scientific society .
It means that the prime aim of ESTRO is to bring to bring people together on an individual basis who have a common interest in improving the scientific conduct of radiotherapy and cancer treatment in Europe by ensuring that proper radiotherapy is available in the multidisciplinary treatment of cancer and applied with the right indication and with the most optimal technique .
One of the main aims of this endeavour was to create a platform for scientific exchange through meetings and through the establishment of a scientific journal [ 1 ] .
Thus Radiotherapy and Oncology was launched shortly after the foundation of ESTRO and has become the society ’s prime vehicle for scientific communication by serving ESTRO members through almost the entire 30 years of the society ’s existence .
The aim was to create a peer review ed high quality international journal and that aim has indeed been fulfilled . ‘ ‘
Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers: results of the EORTC 22851 randomized trial.
BACKGROUND AND PURPOSE A 5 week-hyperfractionated and accelerated radiotherapy regimen without reduction of the total dose was developed to fight tumour re population during treatment and tumour hypoxia . The purpose of the study was to try to improve loco-regional control in high risk head and neck carcinoma treated with curative radiotherapy .  METHODS AND MATERIAL S From 1985 to 1995 , a r and omised controlled trial of the EORTC Cooperative Group of Radiotherapy ( EORTC 22851 ) compared the experimental regimen ( 72 Gy/45 fractions/5 weeks ) to st and ard fractionation and overall treatment time ( 70 Gy/35 fractions/7 weeks ) in T2 , T3 and T4 head and neck cancers ( hypopharynx excluded ) . The end-point criteria were local and loco-regional control , overall and disease-free survival , and acute and late toxicities .  Five hundred twelve patients were accrued . RESULTS Patients in the AF ( accelerated fractionation ) arm did significantly better with regard to loco-regional control ( P = 0.02 ) result ing at 5 years in a 13 % gain ( 95 % CI 3 - 23 % gain ) in loco-regional control over the CF ( conventional fractionation ) arm . This improvement is of larger magnitude in patients with poorer prognosis ( N2 - 3 any T , T4 any N ) than in patients with more favourable stage . Multivariate analysis confirmed AF as an independent prognostic factor of good prognosis for loco-regional control ( P = 0.03 ) . Specific survival shows a trend ( P = 0.06 ) in favour of the AF arm . ACUTE AND LATE TOXICITIES : Acute and late toxicity were increased in the AF arm . Late severe functional irradiation damage occurred in 14 % of patients of the AF arm versus 4 % in the CF arm . Two cases of radiation-induced myelitis occurred after doses of 42 and 48 Gy to the spinal cord . CONCLUSIONS This trial shows that accelerated radiotherapy improves loco-regional control in head and neck squamous cell carcinomas . A less toxic scheme should , however , be investigated and documented before using accelerated radiotherapy as a st and ard regimen of curative radiotherapy for head and neck cancers
Both journals are anchored in large scientific societies and serve basically the same medical , physical and biological community and at the same scientific level ; the two journals are in the most recent Impact Factor list ranked almost back to back , indicating an equal importance and contribution to science .
Radiotherapy and Oncology is more than a scientific journal , it also serves other purpose s such as facilitate education through ( educational ) review s and improving the st and ard of care by bringing forward guidelines for conduct of radiotherapy .
Finally , the journal also tries to maintain a communication platform between the science produced by the membership of ESTRO and therefore it brings papers frommembers in the different European countries , sometimes at the expense of ultimate scientific quality , but with the underst and ing that it is important that the entire ESTRO membership gets access and opportunity to publish in a high ranked journal .
ESTRO , the European Society for Therapeutic Radiation Oncology , or with its new name European Society for Radiation Oncology , is a scientific society .
It means that the prime aim of ESTRO is to bring to bring people together on an individual basis who have a common interest in improving the scientific conduct of radiotherapy and cancer treatment in Europe by ensuring that proper radiotherapy is available in the multidisciplinary treatment of cancer and applied with the right indication and with the most optimal technique .
One of the main aims of this endeavour was to create a platform for scientific exchange through meetings and through the establishment of a scientific journal [ 1 ] .
Thus Radiotherapy and Oncology was launched shortly after the foundation of ESTRO and has become the society ’s prime vehicle for scientific communication by serving ESTRO members through almost the entire 30 years of the society ’s existence .
The aim was to create a peer review ed high quality international journal and that aim has indeed been fulfilled . ‘ ‘