Within spinal pain , patients with neck pain were found to have the highest prevalence rates of MTrPs .
The trapezius descendens , levator scapulae , and suboccipitales muscles were the most prevalent locations for active MTrPs in patients with neck pain .
Latent MTrPs were present in asymptomatic people , but no significant differences were found in the prevalence rate of latent MTrPs between patients with spinal ( neck ) pain and healthy controls .
The only study investigating prevalence of MTrPs in different localizations of the same muscle reported no significant differences in prevalence between active and latent MTrPs within the trapezius descendens muscle .
Studies examining pathophysiological mechanisms underlying MTrPs demonstrated an acidic environment , high concentration of algogenic/inflammatory substances , stiffer muscle tissue , retro grade diastolic blood flows , spontaneous muscle activity at rest , and loss of muscle contractibility in muscles with MTrPs .
Altered central processing was also found to play a role in the development of MTrPs .
Myofascial trigger points are a prevalent clinical entity , especially in patients with neck pain .
Evidence was not found to support or deny the role of MTrPs in other spinal pain .
Compelling evidence supports local mechanisms underlying MTrPs .
OBJECTIVE A systematic review was performed to evaluate the existing evidence related to the prevalence , incidence , localization , and pathophysiology of myofascial trigger points ( MTrPs ) in patients with spinal ( back and neck ) pain .
The nuts and bolts of PROSPERO: an international prospective register of systematic reviews
Background Following publication of the PRISMA statement , the UK Centre for Review s and Dissemination ( CRD ) at the University of York in Engl and began to develop an international prospect i ve register of systematic review s with health-related outcomes . The objectives were to reduce unplanned duplication of review s and provide transparency in the review process , with the aim of minimizing reporting bias . Methods An international advisory group was formed and a consultation undertaken to establish the key items necessary for inclusion in the register and to gather views on various aspects of functionality . This article describes the development of the register , now called PROSPERO , and the process of registration . Results PROSPERO offers free registration and free public access to a unique prospect i ve register of systematic review s across all areas of health from all around the world . The dedicated web-based interface is electronically search able and available to all prospect i ve registrants . At the moment , inclusion in PROSPERO is restricted to systematic review s of the effects of interventions and strategies to prevent , diagnose , treat , and monitor health conditions , for which there is a health-related outcome .Ideally , registration should take place before the research ers have started formal screening against inclusion criteria but review s are eligible as long as they have not progressed beyond the point of completing data extraction .The required data set captures the key attributes of review design as well as the administrative details necessary for registration .Su bmi tted registration forms are checked against the scope for inclusion in PROSPERO and for clarity of content before being made publicly available on the register , rejected , or returned to the applicant for clarification . The public records include an audit trail of major changes to planned methods , details of when the review has been completed , and links to result ing publications when provided by the authors . Conclusions There has been international support and an enthusiastic response to the principle of prospect i ve registration of protocol s for systematic review s and to the development of PROSPERO .In October 2011 , PROSPERO contained 200 records of systematic review s being undertaken in 26 countries around the world on a diverse range of interventions
Within spinal pain , patients with neck pain were found to have the highest prevalence rates of MTrPs .
The trapezius descendens , levator scapulae , and suboccipitales muscles were the most prevalent locations for active MTrPs in patients with neck pain .
Latent MTrPs were present in asymptomatic people , but no significant differences were found in the prevalence rate of latent MTrPs between patients with spinal ( neck ) pain and healthy controls .
The only study investigating prevalence of MTrPs in different localizations of the same muscle reported no significant differences in prevalence between active and latent MTrPs within the trapezius descendens muscle .
Studies examining pathophysiological mechanisms underlying MTrPs demonstrated an acidic environment , high concentration of algogenic/inflammatory substances , stiffer muscle tissue , retro grade diastolic blood flows , spontaneous muscle activity at rest , and loss of muscle contractibility in muscles with MTrPs .
Altered central processing was also found to play a role in the development of MTrPs .
Myofascial trigger points are a prevalent clinical entity , especially in patients with neck pain .
Evidence was not found to support or deny the role of MTrPs in other spinal pain .
Compelling evidence supports local mechanisms underlying MTrPs .
OBJECTIVE A systematic review was performed to evaluate the existing evidence related to the prevalence , incidence , localization , and pathophysiology of myofascial trigger points ( MTrPs ) in patients with spinal ( back and neck ) pain .