Reports of strong associations in small observational studies without appropriate adjustment for potential confounding factors were not generally confirmed by larger and better- design ed studies .
The available evidence indicates that there is no strong association between H pylori and dyspepsia , but there is insufficient evidence to confirm or refute the existence of a modest association
BACKGROUND Previous studies have yielded conflicting results and substantial uncertainty about any independent association of Helicobacter pylori infection with dyspepsia , and about any benefits of antibiotic treatments for nonulcer or uninvestigated dyspepsia .
OBJECTIVES To perform a systematic review of the literature to determine whether chronic infection with H pylori is relevant to nonulcer or uninvestigated dyspepsia .
A placebo controlled trial of bismuth salicylate in Helicobacter pylori associated gastritis.
In a placebo controlled prospect i ve clinical trial of bismuth salicylate in helicobacter pylori associated gastritis  , 52 adult patients were r and omly allocated to treatment with bismuth salicylate or placebo .  Helicobacter pylori were totally cleared in 77 % patients in bismuth group but none in placebo group ( P less than 0.001 ) . Resolution of gastritis ( P less than 0.001 ) and improvement of symptoms ( P less than 0.01 ) were significantly better in patients where H. pylori infection cleared as compared to patients where the infection persisted
Reports of strong associations in small observational studies without appropriate adjustment for potential confounding factors were not generally confirmed by larger and better- design ed studies .
The available evidence indicates that there is no strong association between H pylori and dyspepsia , but there is insufficient evidence to confirm or refute the existence of a modest association
BACKGROUND Previous studies have yielded conflicting results and substantial uncertainty about any independent association of Helicobacter pylori infection with dyspepsia , and about any benefits of antibiotic treatments for nonulcer or uninvestigated dyspepsia .
OBJECTIVES To perform a systematic review of the literature to determine whether chronic infection with H pylori is relevant to nonulcer or uninvestigated dyspepsia .