Conclusion The analysis indicated possible decreasing effect of resveratrol on CRP , but it might not be able to change IL-6 and TNF-α concentrations .
Background Resveratrol as a polyphenolic compound might be able to reduce inflammatory mediators .
Change in inflammatory state is identified by the measurement of inflammatory mediators such as interleukin-6 ( IL-6 ) , tumor necrosis factor-alpha ( TNF-α ) , and C-reactive protein ( CRP ) .
The objective of this study is to conduct a systematic review and meta- analysis on r and omized controlled trials that assessed the effect of resveratrol on concentration of serum inflammatory mediators .
Effects of Polygonum Cuspidatum Containing Resveratrol on Inflammation in Male Professional Basketball Players
Background : Exercise can lead to acute oxidative stress , which can result in oxidative damage and induce inflammation . Resveratrol may reduce the levels of inflammatory cytokines . Thus , we investigated the effects of this compound on the plasma levels of tumor necrosis factor-α ( TNF-α ) and interleukin 6 ( IL-6 ) in male professional basketball players . Methods : Twenty healthy male professional basketball players were r and omized into two groups ( 10 each ) . For 6 weeks , they received daily either 200 mg of polygonum cuspidatum extract ( PCE ) st and ardized to contain 20 % trans-resveratrol equivalent to 40 mg trans-resveratrol or placebo . Indices of inflammation were measured before and after 6 weeks of supplementation . Results : There was a significant reduction in plasma levels of TNF-a and IL-6 after 6 weeks of supplementation ; while no change was observed in these markers in the control group . Conclusions : Present study shows that 6 weeks of PCE containing resveratrol supplementation reduces the inflammation in male professional basketball players
Conclusion The analysis indicated possible decreasing effect of resveratrol on CRP , but it might not be able to change IL-6 and TNF-α concentrations .
Background Resveratrol as a polyphenolic compound might be able to reduce inflammatory mediators .
Change in inflammatory state is identified by the measurement of inflammatory mediators such as interleukin-6 ( IL-6 ) , tumor necrosis factor-alpha ( TNF-α ) , and C-reactive protein ( CRP ) .
The objective of this study is to conduct a systematic review and meta- analysis on r and omized controlled trials that assessed the effect of resveratrol on concentration of serum inflammatory mediators .