Weight loss diet beneficially affects blood adiponectin concentrations .
Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass .
However , the magnitude of the effect of low calorie diet on adiponectin concentrations remains unknown .
The present study was aim ed to conduct a systematic review and meta- analysis on clinical trials that access the effect of low calorie diet on adiponectin concentration .
Influence of Weight Loss, Body Composition, and Lifestyle Behaviors on Plasma Adipokines: A Randomized Weight Loss Trial in Older Men and Women with Symptomatic Knee Osteoarthritis
Objective . To investigate effects of weight loss on adipokines and health measures in obese older adults with symptomatic knee osteoarthritis . Methods . Participants were r and omly assigned to either weight loss ( WL ) ( men : 12 , women : 14 ) or weight stable ( WS ) group ( men : 12 , women : 13 ) .  WL intervention included meal replacements and structured exercise training .  Measurements of leptin , adiponectin , soluble leptin receptor , lifestyle behaviors , and body composition were collected at baseline and 6 months . Univariate analysis of covariance was performed on 6 month variables , and Spearman and partial correlations were made between variables . Results . Weight loss was 13.0 % and 6.7 % in WL for men and women , respectively . Women in WL had lower whole body and trunk fat than WS . The leptin : adiponectin ratio was lower for women in WL than WS at 6 months , with no group differences in adipokines for men . Leptin and free leptin index correlated with body fat in both genders at baseline . Interestingly , only women showed reductions in leptin ( P < 0.100 ) and correlations between the percentage change leptin and trunk fat and the percentage changes in free leptin index with total fat and trunk fat . Partial correlations between 6 month adipokines after adjustments for covariates and group/time period show potential multivariate influences . Conclusions . In the presence of an effective weight loss intervention in older obese adults , there are significant relationships between weight and fat loss and leptin in women , but not men , suggesting gender-specific features of adipokine metabolism in this age group
Weight loss diet beneficially affects blood adiponectin concentrations .
Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass .
However , the magnitude of the effect of low calorie diet on adiponectin concentrations remains unknown .
The present study was aim ed to conduct a systematic review and meta- analysis on clinical trials that access the effect of low calorie diet on adiponectin concentration .