The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .
The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study.
In order to compare the antiplaque and antigingivitis activity of three commercially-available triclosan containing dentifrices with that of a placebo dentifrice without triclosan , a double-blind clinical study was conducted on 194 subjects over six months . Following baseline supragingival plaque and gingivitis examinations and a complete oral prophylaxis , subjects were stratified by their whole mouth baseline plaque ( modified Quigley-Hein ) and gingivitis ( modified Löe-Silness ) scores and then r and omly assigned to one of four dentifrice using groups . Plaque and gingivitis examinations were then performed after six weeks , three months and six months use of the dentifrices . Subjects brushed twice daily in their customary manner . The triclosan/soluble pyrophosphate and the triclosan/zinc citrate commercially available dentifrices did not provide statistically significant reductions in either supragingival plaque accumulation or gingivitis at any of the examination intervals , as compared to the placebo dentifrice . The subjects using the commercially available triclosan/copolymer dentifrice had , after six months , statistically significant reductions in supragingival plaque ( 11.3 per cent ) , plaque severity ( 18.8 per cent ) , gingivitis ( 19.9 per cent ) and gingivitis severity ( 27.8 per cent ) , as compared to the placebo dentifrice
The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .