These meta-analyses found no statistically significant differences between the efficacy of propranolol and benzodiazepines regarding the short-term treatment of panic disorder with or without agoraphobia .
Also , no evidence was found for effects of propranolol on PTSD symptom severity through inhibition of memory reconsolidation .
In conclusion , the quality of evidence for the efficacy of propranolol at present is insufficient to support the routine use of propranolol in the treatment of any of the anxiety disorders
The effects of propranolol in the treatment of anxiety disorders have not been systematic ally evaluated previously .
The aim was to conduct a systematic review and meta- analysis of r and omised controlled trials , addressing the efficacy of oral propranolol versus placebo or other medication as a treatment for alleviating either state or trait anxiety in patients suffering from anxiety disorders .
The effect of acute beta-adrenoceptor blockade on examination performance.
Simple tests of verbal reasoning and mental arithmetic , taken under mildly stressful conditions , have been shown to give a reproducible test of intellectual function within groups of normal subjects . Using these tests , in two separate examinations , a double-blind cross-over study was performed on 35 medical students to assess the effects of acute beta-adrenoceptor blockade with propranolol on intellectual function . With placebo treatment , students recorded an average total score of 231.3 marks , with average scores of 108.9 marks on the mental arithmetic paper and 122.4 marks on the verbal reasoning paper . Treatment with propranolol was associated with an improvement in total score of 9.2 + /- 3.9 marks ( P less than 0.05 ) , an improvement in mental arithmetic score of 5.6 + /- 2.3 marks ( P less than 0.05 ) and an improvement in verbal reasoning score of 3.6 + /- 2.4 marks ( NS ) . Eighteen out of the 35 students said that they were mildly anxious before one examination and 13 students said they were anxious before both examinations . Those students who admitted anxiety seemed to benefit the most , in terms of improved examination performance , from treatment with propranolol
These meta-analyses found no statistically significant differences between the efficacy of propranolol and benzodiazepines regarding the short-term treatment of panic disorder with or without agoraphobia .
Also , no evidence was found for effects of propranolol on PTSD symptom severity through inhibition of memory reconsolidation .
In conclusion , the quality of evidence for the efficacy of propranolol at present is insufficient to support the routine use of propranolol in the treatment of any of the anxiety disorders
The effects of propranolol in the treatment of anxiety disorders have not been systematic ally evaluated previously .
The aim was to conduct a systematic review and meta- analysis of r and omised controlled trials , addressing the efficacy of oral propranolol versus placebo or other medication as a treatment for alleviating either state or trait anxiety in patients suffering from anxiety disorders .