Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .
Short-term very low calorie diet reduces oxidative stress in obese type 2 diabetic patients.
Oxidative stress is higher in obese diabetic than in non-diabetic subjects . This pilot study evaluates oxidative stress during short-term administration of a very low calorie diet in obese persons . Nine obese Type 2 diabetic patients ( age 55+/-5 years , BMI 35.9+/-1.9 kg/m2 ) and nine obese non-diabetic control subjects ( age 52+/-6 years , BMI 37.3+/-2.1 kg/m2 ) were treated by a very low calorie diet ( 600 kcal daily ) during 8 days stay in the hospital . Serum cholesterol , triglycerides , non-esterified fatty acids ( NEFA ) , beta-hydroxybutyrate ( B-HB ) , ascorbic acid ( AA ) , alpha-tocopherol ( AT ) , plasma malondialdehyde ( MDA ) and superoxide dismutase ( SOD ) activity in erythrocytes were measured before and on day 3 and 8 of very low calorie diet administration . A decrease of serum cholesterol and triglyceride concentrations on day 8 was associated with a significant increase of NEFA ( 0.30+/-0.13 vs. 0.47+/-0.11 micromol/l , p<0.001 ) and B-HB ( 0.36+/-.13 vs. 2.23+/-1.00 mmol/l , p<0.001 ) in controls but only of B-HB ( 1.11+/-0.72 vs. 3.02+/-1.95 mmol/l , p<0.001 ) in diabetic patients . A significant decrease of plasma MDA and serum AT together with an increase of SOD activity and AA concentration ( p<0.01 ) was observed in control persons , whereas an increase of SOD activity ( p<0.01 ) was only found in diabetic patients after one week of the very low calorie diet . There was a significant correlation between NEFA or B-HB and SOD activity ( p<0.01 ) . We conclude that one week of a very low calorie diet administration decreases oxidative stress in obese non-diabetic but only partly in diabetic persons . Diabetes mellitus causes a greater resistance to the effects of a low calorie diet on oxidative stress
Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .