Using mean data from the validation study , the trend and directionality in risk was similar in the Roux-en-Y group .
In conclusion , bariatric surgery predicts long-term decreases in CV risk in obese patients
Obese patients have an increased prevalence of  cardiovascular ( CV ) risk factors , which improve with bariatric surgery , but whether bariatric surgery reduces long-term CV events remains ill defined .
Short-term effects of weight loss on the cardiovascular risk factors in morbidly obese patients.
OBJECTIVE To analyze the short-term effects of weight loss on the cardiovascular risk factors in morbidly obese patients . RESEARCH METHODS AND PROCEDURES Five metabolic cardiovascular risk factors ( blood glucose , blood pressure , total cholesterol , high-density lipoprotein (HDL)-cholesterol , and triglycerides ) were determined before and 15.3 + /- 2.1 months after  laparoscopic gastric b and ing in 650 morbidly obese patients .  Global cardiovascular risk was calculated according to the Prospect i ve Cardiovascular Münster ( PROCAM ) scoring system . RESULTS Mean weight loss was 22.7 + /- 20.4 kg . Normalization of the metabolic alteration was observed in 67.3 % of patients with diabetes , 38.3 % of patients with hypercholesterolemia , 72.5 % of patients with low HDL-cholesterol , 72.3 % of patients with hypertriglyceridemia , and 46.7 % of patients with hypertension . PROCAM score fell from 31.4 + /- 11.6 to 28.0 + /- 12.0 points ( p < 0.001 ) . The modifications of total cholesterol and blood pressure were unrelated to percentage weight loss . Percentage weight loss was significantly related to the reductions of fasting blood glucose , triglyceride level , and the PROCAM score and to the increase of HDL-cholesterol concentrations observed after surgery . However , the strength of these four relationships was generally low . The variations of HDL-cholesterol concentrations and blood pressure levels were more influenced by actual energy balance than by the extent of weight loss . DISCUSSION Weight loss observed in the first 12 to 18 months after gastric b and ing was associated with a significant improvement of single cardiovascular risk factors and global risk . On the other h and , the extent of weight loss was poorly related to the magnitude of improvement in cardiovascular risk
Using mean data from the validation study , the trend and directionality in risk was similar in the Roux-en-Y group .
In conclusion , bariatric surgery predicts long-term decreases in CV risk in obese patients
Obese patients have an increased prevalence of  cardiovascular ( CV ) risk factors , which improve with bariatric surgery , but whether bariatric surgery reduces long-term CV events remains ill defined .