Neither metoclopramide nor erythromycin were effective in expediting the resolution of ileus .
Analyses of 32 r and omized controlled trials showed that EEN facilitates return of normal bowel function , achieving enteral nutrition goals , and reducing hospital length of stay .
CONCLUSION In patients who have undergone abdominal surgery , we strongly recommend EEN to expedite resolution of Ileus , but we can not recommend for or against the use of either metoclopramide or erythromycin to hasten the resolution of ileus in these patients .
BACKGROUND Ileus is a common challenge in adult surgical patients with estimated incidence to be 17 % to 80 % .
The main mechanisms of the postoperative ileus pathophysiology are fluid overload , exogenous opioids , neurohormonal dysfunction , gastrointestinal stretch , and inflammation .
Management includes addressing the underlying cause and supportive care .
Multiple medical interventions have been proposed , but effectiveness is uncertain .
A working group of the Eastern Association for the Surgery of Trauma aim ed to evaluate the effectiveness of metoclopramide , erythromycin , and early enteral nutrition ( EEN ) on ileus in adult surgical patients and to develop recommendations applicable in a daily clinical practice .
Comparing early oral feeding with traditional oral feeding in upper gastrointestinal surgery.
BACKGROUND / AIMS Due to the lack of interest in using early oral feeding and the need for a trial study in this regard , this study aim ed to compare the outcome of early oral feeding and traditional oral feeding in patients with upper gastrointestinal surgery . METHODS Fifty-two patients who underwent upper gastrointestinal surgery were r and omly assigned into two groups in a consecutive manner as either the early oral feeding group or traditional oral feeding group .  Tolerance of oral feeding , ileus , nausea and vomiting , post-operative stay , and complications were recorded . RESULTS Tolerance of oral feeding for the two groups was 24 ( 92.3 % ) in the early oral feeding group and 21 ( 91.3 % ) in the traditional oral feeding group ( p=0.89 ) . The post-operative hospital stays were 5.62 and 8.04 days in the early oral feeding and traditional oral feeding groups , respectively ( p<0.0001 ) . There were significant differences between the two groups in terms of the time of the first gas passing/defecation , the post-operative hospital stays , starting time of oral feeding , and satisfaction regarding early nasogastric tube removal . CONCLUSIONS The results of this study show that early oral feeding is a safer and more cost-effective procedure in upper gastrointestinal surgery
Neither metoclopramide nor erythromycin were effective in expediting the resolution of ileus .
Analyses of 32 r and omized controlled trials showed that EEN facilitates return of normal bowel function , achieving enteral nutrition goals , and reducing hospital length of stay .
CONCLUSION In patients who have undergone abdominal surgery , we strongly recommend EEN to expedite resolution of Ileus , but we can not recommend for or against the use of either metoclopramide or erythromycin to hasten the resolution of ileus in these patients .
BACKGROUND Ileus is a common challenge in adult surgical patients with estimated incidence to be 17 % to 80 % .
The main mechanisms of the postoperative ileus pathophysiology are fluid overload , exogenous opioids , neurohormonal dysfunction , gastrointestinal stretch , and inflammation .
Management includes addressing the underlying cause and supportive care .
Multiple medical interventions have been proposed , but effectiveness is uncertain .
A working group of the Eastern Association for the Surgery of Trauma aim ed to evaluate the effectiveness of metoclopramide , erythromycin , and early enteral nutrition ( EEN ) on ileus in adult surgical patients and to develop recommendations applicable in a daily clinical practice .