Probiotic supplementation showed beneficial effect in the prevention and treatment of radiation-induced diarrhea in experimental animal studies .
BACKGROUND AND AIMS Probiotic supplementation seems to provide beneficial effects in the prevention and treatment of  radiation-induced diarrhea .
We performed a systematic review and meta- analysis to estimate the efficacy of probiotic supplementation for prevention and treatment of  radiation-induced diarrhea .
Preservation of intestinal integrity during radiotherapy using live Lactobacillus acidophilus cultures.
Twenty-four female patients suffering from gynaecological malignancies and scheduled for internal and external irradiation of the pelvic area ( pelvic dose 5000 cGy ) were selected for a study on prevention of intestinal side-effects by live Lactobacillus acidophilus cultures . The patients were r and omised into two groups . Both groups received dietary counselling recommending a low-fat and low-residue diet during radiotherapy . The control group received dietary counselling only . The test group received 150 ml of a fermented milk test product supplying them with at least 2 X 10(9 ) live Lactobacillus acidophilus bacteria daily and 6.5 % lactulose as substrate for the bacteria . The results indicated that the test product appeared to prevent radiotherapy-associated diarrhoea . However , flatulence was increased probably due to lactulose ingestion in the test group
Probiotic supplementation showed beneficial effect in the prevention and treatment of radiation-induced diarrhea in experimental animal studies .
BACKGROUND AND AIMS Probiotic supplementation seems to provide beneficial effects in the prevention and treatment of  radiation-induced diarrhea .
We performed a systematic review and meta- analysis to estimate the efficacy of probiotic supplementation for prevention and treatment of  radiation-induced diarrhea .