Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .
Effect of cranberry juice consumption on urinary stone risk factors.
PURPOSE We evaluated the effect of cranberry juice on urinary stone risk factors . MATERIAL S AND METHODS A total of 12 normal subjects and 12 calcium oxalate stone formers underwent 2 , 7-day phases of study in r and om order while on a controlled metabolic diet . Subjects ingested 1 l of cranberry juice ( CBJ ) daily in 1 phase and 1 l of deionized water in the other phase . On the last 2 days of each phase 2 , 24-hour urine collection s and blood sample s were obtained for stone risk factors and serum chemistries . RESULTS No significant differences were found between normal subjects and stone formers in response to CBJ and , therefore , the groups were combined . CBJ significantly increased urinary calcium ( from 154 to 177 mg per day , p = 0.0008 ) and urinary oxalate ( from 26.4 to 29.2 mg per day , p = 0.04 ) , thereby increasing urinary saturation of calcium oxalate by 18 % . Urinary citrate was unchanged and urinary magnesium increased slightly . Urinary pH decreased ( from 5.97 to 5.67 , p = 0.0005 ) , and urinary ammonium , titratable acidity and net acid excretion increased during CBJ ingestion . Urinary uric acid decreased ( from 544 to 442 mg per day , p < 0.0001 ) as did serum uric acid . Thus , the urinary saturation of brushite and monosodium urate was reduced by CBJ but the amount of undissociated uric acid increased . CONCLUSIONS CBJ exerts a mixed effect on urinary stone forming propensity . It reduces urinary pH likely by providing an acid load and decreases urinary uric acid perhaps by retarding urate synthesis . Overall CBJ increases the risk of calcium oxalate and uric acid stone formation but decreases the risk of brushite stones
Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .