In comparison with the baseline , NNS consumption was not found to increase blood glucose level , and its concentration gradually declined over the course of observation following NNS consumption .
The glycemic impact of NNS consumption did not differ by type of NNS but to some extent varied by participants ’ age , body weight , and diabetic status .
Conclusions NNS consumption was not found to elevate blood glucose level .
Background / objectives Nonnutritive sweeteners ( NNSs ) are zero- or low-calorie alternatives to nutritive sweeteners , such as table sugars .
A systematic review and meta- analysis of r and omized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of NNSs .
Placebo expectancy effects in the relationship between glucose and cognition.
The present study investigated the extent of expectancy in the ability of glucose to affect cognitive performance . Using a within-subjects design , subjects ( n 26 ) completed four experimental sessions ( in counterbalanced order and after an initial practice session ) during which they were given a 500 ml drink 30 min prior to completing a cognitive assessment battery . In addition , all subjects completed a baseline practice session during which they were given no drink . During two of the sessions , subjects were given a drink containing 50 g glucose and on the other two they were given a drink containing aspartame . A balanced placebo design was used , such that for half the sessions subjects were accurately informed as to the content of the drink ( glucose or aspartame ) , whereas in the other two sessions they were misinformed as to the content of the drink . The task battery comprised a 6 min visual analogue of the  Bakan vigilance task  , an immediate verbal free-recall task , an immediate verbal recognition memory task and a measure of motor speed ( two-finger tapping ) . Blood glucose and self-reported mood were also recorded at several time points during each session . Glucose administration was found to improve recognition memory times , in direct contrast to previous findings in the literature . Glucose administration also improved performance on the Bakan task ( relative to the control drink ) , but only in sessions where subjects were informed that they would receive glucose and not when they were told that they would receive aspartame . There were no effects either of the nature of the drink or expectancy on the other measures . These results are interpreted in terms of there being some contribution of expectancy concerning the positive effects of glucose on cognition in studies which have not used an equi-sweet dose of aspartame as a control drink
In comparison with the baseline , NNS consumption was not found to increase blood glucose level , and its concentration gradually declined over the course of observation following NNS consumption .
The glycemic impact of NNS consumption did not differ by type of NNS but to some extent varied by participants ’ age , body weight , and diabetic status .
Conclusions NNS consumption was not found to elevate blood glucose level .
Background / objectives Nonnutritive sweeteners ( NNSs ) are zero- or low-calorie alternatives to nutritive sweeteners , such as table sugars .
A systematic review and meta- analysis of r and omized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of NNSs .