CONCLUSIONS At least one PROM with some evidence for aspects of validity and reliability was available for six of the eight m and atory domains of the PsA COS
BACKGROUND An up date d psoriatic arthritis ( PsA ) core outcome set ( COS ) for r and omized controlled trials ( RCTs ) was endorsed at the Outcome Measures in Rheumatology ( OMERACT ) meeting in 2016 .
OBJECTIVES To synthesize the evidence on measurement properties of patient reported outcome measures ( PROMs ) for PsA and thereby contribute to development of a PsA core outcome measurement set ( COMS ) as described by the OMERACT Filter 2.0 .
Responsiveness of health status instruments to changes in articular status and perceived health in patients with psoriatic arthritis.
OBJECTIVE To compare the responsiveness of the Health Assessment Question naire ( HAQ ) , Arthritis Impact Measurement Scale 2 ( AIMS 2 ) , and Medical Outcome Study Short Form Health Survey ( SF-36 ) to changes in articular status and perceived health in out patients with psoriatic arthritis ( PsA ) . METHODS The 3 health status instruments were administered in r and om order on 2 occasions , about 12 - 18 months apart , to 70 patients attending the University of Toronto psoriatic arthritis clinic . St and ardized assessment s of disease activity , disease severity , and general health perceptions were also performed at each clinic visit . To assess responsiveness we used : ( 1 ) linear regression analyses to relate change scores for perceived health , the number of actively inflamed , and damaged joints to change scores for selected dimensions of the HAQ , AIMS 2 , and SF-36 ; ( 2 ) logistic regression analyses to relate both improvement in disease activity and disease progression to health status change scores ; and ( 3 ) st and ardized response means ( SRM ) . RESULTS There were 43 men and 27 women with a mean age of 46 years and arthritis duration of 13 years . Univariate regression analyses showed that the individual instruments were responsive to perceived changes in health , but relatively insensitive to detect changes in articular status . Multivariate regression analyses , in which the common dimensions of the instruments were jointly entered , indicated the SF-36 was equally or more responsive to changes in number of actively inflamed joints , clinical improvement in disease activity , and perceived health than the HAQ and AIMS 2 . The SRM analysis also suggested that the SF-36 was the most responsive . CONCLUSION The SF-36 proved equally or more responsive to short term changes in perceived health and inflammatory disease activity ; however , none of the instruments showed responsiveness to disease progression
CONCLUSIONS At least one PROM with some evidence for aspects of validity and reliability was available for six of the eight m and atory domains of the PsA COS
BACKGROUND An up date d psoriatic arthritis ( PsA ) core outcome set ( COS ) for r and omized controlled trials ( RCTs ) was endorsed at the Outcome Measures in Rheumatology ( OMERACT ) meeting in 2016 .
OBJECTIVES To synthesize the evidence on measurement properties of patient reported outcome measures ( PROMs ) for PsA and thereby contribute to development of a PsA core outcome measurement set ( COMS ) as described by the OMERACT Filter 2.0 .