For most comparisons , the credibility of evidence was rated very low to moderate , with the exception for the DASH vs. the low-fat dietary approach for which the quality of evidence was rated high .
Conclusion : The present network meta- analysis suggests that the DASH dietary approach might be the most effective dietary measure to reduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
ABSTRACT Background : Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood pressure but their comparative effects have not been established .
Objective : Therefore we performed a systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects through network meta- analysis including hypertensive and pre-hypertensive patients .
Weight reduction in patients with coronary artery disease: comparison of Traditional Tibetan Medicine and Western diet.
BACKGROUND To test alternative medicine approaches with a specifically design ed Tibetan dietary and behavioral program in patients with established coronary artery disease ( CAD ) and manifest metabolic syndrome . METHODS This was a r and omized , controlled , double-blinded , parallel group dietary and behavioral intervention study . Between December 2008 and November 2010 , patients were r and omly adjudicated either to evidence -based Western diet ( usual care ) , or to Tibetan diet . We evaluated 524 patients undergoing coronary angiography . All patients were white Caucasian , presented with a body mass index ( BMI ) > 25 kg/m(2 ) , and had evidence of metabolic syndrome . The primary endpoint was change in body weight and BMI at 6 months follow-up . Secondary endpoints included blood pressure , heart rate , intima media thickness , lipids , fasting glucose , glycated hemoglobin , fibrinogen , C-reactive protein ( CRP ) at 6 months follow-up and change in body weight and BMI at 12 months . RESULTS Both groups of patients showed significantly reduced body weight and BMI compared to baseline ( 6 months , usual care weight change : -3.2 ± 3.0 kg ; BMI change : -1.1 ± 1.0 kg/m(2 ) ; Tibetan diet weight change : -6.2 ± 4.4 kg/m(2 ) ; BMI change : -2.1 ± 1.5 kg/m(2 ) ) , but these changes were more pronounced in Tibetan diet compared to usual care ( all , p<0.001 ) . Beneficial effects on weight and BMI were maintained after 12 months of follow-up ( p<0.0001 ) . Levels of total and LDL cholesterols , fibrinogen and CRP were decreased in both groups , but more pronounced in Tibetan diet ( Tibetan diet vs. usual care ( total cholesterol ) : 176.2 ± 43.7 vs. 185.1 ± 47.8 mg/dL ; p=0.024 ; LDL : 111.6 ± 37.8 vs. 119.4 ± 40.9 mg/dL ; p=0.026 ; fibrinogen : 318.3 ± 90.4 vs. 334.1 ± 87.9 mg/dL ; p=0.040 ; CRP : 1.2 ± 3.0 vs. 2.2 ± 4.5mg/dL ; p=0.036 ) . CONCLUSIONS Tibetan diet reduces body weight and BMI in patients with CAD and metabolic syndrome after 6 months significantly better than Western diet and may induce lipid-modifying and anti-inflammatory effects ( Clinical Trials.gov identifier : NCT00810992 )
For most comparisons , the credibility of evidence was rated very low to moderate , with the exception for the DASH vs. the low-fat dietary approach for which the quality of evidence was rated high .
Conclusion : The present network meta- analysis suggests that the DASH dietary approach might be the most effective dietary measure to reduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
ABSTRACT Background : Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood pressure but their comparative effects have not been established .
Objective : Therefore we performed a systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects through network meta- analysis including hypertensive and pre-hypertensive patients .