Cognitive behavioral therapy may reduce relapse risk for adults with AN after weight restoration , although its efficacy in the underweight state remains unknown .
Variants of family therapy are efficacious in adolescents , but not in adults .
Evidence for AN treatment is weak ; evidence for treatment-related harms and factors associated with efficacy of treatment are weak ; and evidence for differential outcome by sociodemographic factors is nonexistent .
OBJECTIVE The RTI International-University of North Carolina at Chapel Hill Evidence -based Practice Center ( RTI-UNC EPC ) systematic ally review ed evidence on efficacy of treatment for anorexia nervosa ( AN ) , harms associated with treatments , factors associated with treatment efficacy , and differential outcome by sociodemographic characteristics .
Does fluoxetine augment the inpatient treatment of anorexia nervosa?
OBJECTIVE While pharmacological interventions are of established utility in bulimia nervosa , medications have no clear role in the treatment of anorexia nervosa . Because patients with anorexia nervosa frequently exhibit mood disturbances and symptoms of obsessive-compulsive disorder , the authors tested the utility of fluoxetine in the treatment of women participating in an inpatient program for anorexia nervosa . METHOD The authors conducted a r and omized , placebo-controlled , double-blind , 7-week study of fluoxetine at a target daily dose of 60 mg in 31 women with anorexia nervosa receiving treatment for their eating disorder on a clinical research unit .  Body weight and measures of eating behavior and psychological state were obtained at baseline and at termination . RESULTS There were no significant differences in clinical outcome on any measure between patients receiving fluoxetine and patients receiving placebo . CONCLUSIONS Fluoxetine does not appear to add significant benefit to the inpatient treatment of anorexia nervosa
Cognitive behavioral therapy may reduce relapse risk for adults with AN after weight restoration , although its efficacy in the underweight state remains unknown .
Variants of family therapy are efficacious in adolescents , but not in adults .
Evidence for AN treatment is weak ; evidence for treatment-related harms and factors associated with efficacy of treatment are weak ; and evidence for differential outcome by sociodemographic factors is nonexistent .
OBJECTIVE The RTI International-University of North Carolina at Chapel Hill Evidence -based Practice Center ( RTI-UNC EPC ) systematic ally review ed evidence on efficacy of treatment for anorexia nervosa ( AN ) , harms associated with treatments , factors associated with treatment efficacy , and differential outcome by sociodemographic characteristics .