Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .
Testosterone influences spatial cognition in older men.
Testosterone plays a role in the organization of behavior during development . The authors examined whether testosterone could play a maintenance role in behavior as well . In a double-blind manner , verbal and visual memory , spatial cognition , motor speed , cognitive flexibility , and mood in a group of healthy older men who were supplemented for 3 months with testosterone  were assessed . The increase in testosterone levels to 150 % of baseline levels result ed in a significant enhancement of spatial cognition , but no change in any other cognitive domain was found . Testosterone supplementation influenced the endogenous production of estradiol , and estradiol was found to have an inverse relationship to spatial cognitive performance . These results suggest that testosterone supplementation can modify spatial cognition in older men ; however , it is likely that this occurs through testosterone 's influence on estrogen
Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .