None of the trials individually found any statistically significant difference in the incidence of NEC .
However , meta- analysis found that feeding with donor human milk was associated with a significantly reduced relative risk ( RR ) of NEC .
OBJECTIVES To determine if enteral feeding with donor human milk compared with formula milk reduces the incidence of necrotising enterocolitis ( NEC ) in preterm or low birthweight infants .
A COMPARATIVE STUDY OF VARYING PROTEIN INTAKE IN LOW BIRTHWEIGHT INFANT FEEDING
Svenningsen , N.W. , Lindroth , M. and Lindquist , B. ( Department of Paediatrics , University of Lund , Sweden ) . A comparative study of varying protein intake in low birthweight infant feeding . Acta Paediatr Sc and . Suppl . 296 : 28 , 1982 . — In a prospect i ve longitudinal study of 48 very low birthweight and preterm infants with mean birthweight 1 385±343 and gestational age 30.8±2.9 w an assessment was made of the impact of varying the protein intake in the postnatal period from the 3rd to 7th week of life . The infants were r and omly allocated to one of three dietary groups with isocaloric energy supply but different protein content — i.e . human milk ( 1.6 g/100 kcal ) , formula 1 ( 2.3 g/100 kcal ) and formula 2 ( 3.0 g/100 kcal ) . In the human milk group 12 of 18 infants were fed their own mother 's breastmilk . During the study period the mean weight gain was slightly higher in the infants fed formula 1 and 2 . There were no group differences in S‐albumin whereas B‐urea‐N and B‐base deficit were significantly increased in the formula fed infants in comparison to infants fed human milk . After the study period until around 15 weeks of age the slope in weight gain remained slightly higher for formula fed infants . However , the gain in body length and head circumference was equal in all three groups . After around 8 months of age there was no difference in any growth parameter . Neurodevelopmental examinations showed no group differences during the follow‐up period to 2 years of age
None of the trials individually found any statistically significant difference in the incidence of NEC .
However , meta- analysis found that feeding with donor human milk was associated with a significantly reduced relative risk ( RR ) of NEC .
OBJECTIVES To determine if enteral feeding with donor human milk compared with formula milk reduces the incidence of necrotising enterocolitis ( NEC ) in preterm or low birthweight infants .