Conclusions Inositol supplementation may result in reduction in triglycerides , total- and LDL-cholesterol levels , but did not affect HDL-cholesterol levels  among patients with metabolic diseases .
Background Several studies have evaluated the effect of inositol supplementation on lipid profiles among population with metabolic diseases ; however , the findings are controversial .
This review of r and omized controlled trials ( RCTs ) was performed to summarize the evidence of the effects of inositol supplementation on lipid profiles among population with metabolic diseases .
Effects of a dietary supplement on cholesterol in subjects with moderate hypercholesterolemia.
BACKGROUND AND AIMS Prospect i ve studies have demonstrated that the risk of death due to ischaemic heart disease is strongly correlated with blood cholesterol ( TC ) levels . Diet is the basic treatment for all dyslipidaemia . If diet alone proves inadequate , supplements can be used to try to reduce cholesterol levels . These substances are indicated in moderate dyslipidaemia , as they are able to induce a moderate reduction in blood cholesterol . The objective of our study was to investigate the effects of a dietary supplement containing Omega-3 , Policosanol , Resveratrol , L-carnitine , Monascus purpureus , Coenzyme Q10 , Vitamin B6 and Vitamin B12 on TC ( primary end point ) and LDL , triglycerides and HDL ( secondary endpoints ) . PATIENTS AND METHODS The study involved 40 men and 40 women recruited from the outpatient section of our Department r and omly assigned to the treatment group ( A ) or the control group ( B ) . RESULTS There was a statistically significant reduction in TC 6 months after the end of treatment in both groups . In Group A , there was also a statistically significant change in HDL , LDL and TG , while in group B , there was no statistically significant change in HDL , LDL or TG . CONCLUSIONS The dietary supplement used in our study , in combination with a balanced diet and physical exercise , was found to induce a significant reduction in TC and LDL-C and an improvement in HDL-C. In contrast , while a balanced diet together with physical exercise but without the dietary supplement produced a significant reduction in TC , it had no significant effect on the other lipid parameters tested
Conclusions Inositol supplementation may result in reduction in triglycerides , total- and LDL-cholesterol levels , but did not affect HDL-cholesterol levels  among patients with metabolic diseases .
Background Several studies have evaluated the effect of inositol supplementation on lipid profiles among population with metabolic diseases ; however , the findings are controversial .
This review of r and omized controlled trials ( RCTs ) was performed to summarize the evidence of the effects of inositol supplementation on lipid profiles among population with metabolic diseases .