Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .
Increased aggressive responding in male volunteers following the administration of gradually increasing doses of testosterone cypionate.
The present study assessed the effects of supraphysiologic doses of testosterone on  aggressive responding  in a controlled laboratory setting . Eight male subjects received gradually increasing doses of testosterone cypionate ( 150 mg/week for two weeks , 300 mg/week for two weeks , and 600 mg/week for two weeks ) or placebo using a double-blind , r and omized , cross-over design . Subjects were tested both before and after the series of injections . During the experimental session subjects could press a button to accumulate points exchangeable for money ( non-aggressive response ) or press another button to subtract points from a fictitious opponent ( aggressive response ) . Aggressive responding was instigated by subtracting points from the subject which was attributable to the fictitious opponent . Testosterone administration result ed in a significantly higher number of aggressive responding compared to placebo
Testosterone supplementation did not show consistent benefit for cardiovascular risk , sexual function , mood and behavior , or cognition .
Studies that examined clinical cardiovascular endpoints have not favored testosterone therapy over placebo .
Testosterone is ineffective in treating erectile dysfunction and controlled trials did not show a consistent effect on libido .
Testosterone supplementation consistently increased muscle strength but did not have beneficial effects on physical function .
Most studies on mood-related endpoints found no beneficial effect of testosterone treatment on personality , psychological well-being , or mood .
Testosterone products are recommended by some prescribers in response to a diagnosis or presumption of " low testosterone " ( low-T ) for cardiovascular health , sexual function , muscle weakness or wasting , mood and behavior , and cognition .