There is some evidence that haloperidol is an effective treatment for  acute mania .
From the limited data available , there was no difference in overall efficacy of treatment between haloperidol and olanzapine or risperidone .
Some evidence suggests that haloperidol could be less effective than aripiprazole .
BACKGROUND The main objectives in treating mania are to control dangerous behaviour , reduce suicide , produce appropriate acute sedation and shorten the episode of mood disturbance .
Among different drugs , haloperidol has for many years been used in treating psychotic patients , but it has a troublesome side effect profile .
OBJECTIVES To assess the effects of haloperidol for the treatment of mania in comparison with placebo or other active drugs , either as monotherapy or add-on treatment .
Lithium combined with carbamazepine or haloperidol in the treatment of mania.
Hospitalized manic patients were withdrawn from psychoactive medications for 2 weeks after which they were r and omized to double-blind treatment with carbamazepine plus lithium [ CBZ-Li ] or haloperidol plus lithium [ HAL-Li ] with benztropine . Unit dosages of Li 300 mg , CBZ 200 mg and HAL 2 mg were titrated to therapeutic plasma levels and maintained for 8 weeks . No rescue medications were permitted after 3 weeks . St and ard ratings of psychopathology and side effects were accomplished weekly . Sixty patients entered the study but only 33 remained for r and omization after drug washout . By 8 weeks both groups were improved from baseline without statistically reliable differences between them . However HAL-Li patients had more extrapyramidal side effects that were major reasons for dropout , whereas CBZ-Li patients were more often noncompliant and initially required more rescue medications . We conclude that either combination treatment can be beneficial but CBZ-Li has the advantage because of fewer neurologic side effects
There is some evidence that haloperidol is an effective treatment for  acute mania .
From the limited data available , there was no difference in overall efficacy of treatment between haloperidol and olanzapine or risperidone .
Some evidence suggests that haloperidol could be less effective than aripiprazole .
BACKGROUND The main objectives in treating mania are to control dangerous behaviour , reduce suicide , produce appropriate acute sedation and shorten the episode of mood disturbance .
Among different drugs , haloperidol has for many years been used in treating psychotic patients , but it has a troublesome side effect profile .
OBJECTIVES To assess the effects of haloperidol for the treatment of mania in comparison with placebo or other active drugs , either as monotherapy or add-on treatment .