Enduring changes in personality/attitudes , depression , spirituality , anxiety , wellbeing , substance misuse , meditative practice s , and mindfulness were documented .
Mystical experiences , connectedness , emotional breakthrough , and increased neural entropy were related to these long-term changes in psychological functioning .
Finally , with proper screening , preparation , supervision , and integration , limited aversive side effects were noted by study participants .
Research into the basic effects and therapeutic applications of  psychedelic drugs  has grown considerably in recent years .
Yet , pressing questions remain regarding the substances ' lasting effects .
Although individual studies have begun monitoring sustained changes , no study to- date has synthesized this information .
Psychedelics not linked to mental health problems or suicidal behavior: A population study
A recent large population study of 130,000 adults in the United States failed to find evidence for a link between psychedelic use ( lysergic acid diethylamide , psilocybin or mescaline ) and  mental health problems . Using a new data set consisting of 135,095 r and omly selected United States adults , including 19,299 psychedelic users , we examine the associations between psychedelic use and mental health . After adjusting for sociodemographics , other drug use and childhood depression , we found no significant associations between lifetime use of  psychedelics  and increased likelihood of past year serious psychological distress , mental health treatment , suicidal thoughts , suicidal plans and suicide attempt , depression and anxiety . We failed to find evidence that psychedelic use is an independent risk factor for mental health problems .  Psychedelics are not known to harm the brain or other body organs or to cause addiction or compulsive use ; serious adverse events involving psychedelics are extremely rare . Overall , it is difficult to see how prohibition of psychedelics can be justified as a public health measure
Enduring changes in personality/attitudes , depression , spirituality , anxiety , wellbeing , substance misuse , meditative practice s , and mindfulness were documented .
Mystical experiences , connectedness , emotional breakthrough , and increased neural entropy were related to these long-term changes in psychological functioning .
Finally , with proper screening , preparation , supervision , and integration , limited aversive side effects were noted by study participants .
Research into the basic effects and therapeutic applications of  psychedelic drugs  has grown considerably in recent years .
Yet , pressing questions remain regarding the substances ' lasting effects .
Although individual studies have begun monitoring sustained changes , no study to- date has synthesized this information .