The systemic inflammatory response was normalized before or on the seventh postoperative day .
Conclusions Hernia repair elicits a systemic inflammatory response characterized by an increase in CRP , IL-6 , leukocytes , neutrophils , IL-1 , IL-10 , fibrinogen , and α1-antitrypsin and a decrease in lymphocytes and albumin .
A higher inflammatory response was found after mesh repair compared with non-mesh repair and after open mesh repair compared with laparoscopic mesh repair
Purpose All surgical procedures elicit a complex systemic inflammatory response effectuated and modulated by cytokines .
The purpose of this systematic review was to present an overview of the inflammatory response and the serum markers associated with hernia repair and to compare the response between patients treated with and without mesh .
Laparoendoscopic single-site versus conventional laparoscopic total extraperitoneal hernia repair: a prospective randomized clinical trial
Background This study aim ed to compare laparoendoscopic single-site ( LESS ) total extraperitoneal ( TEP ) repair with conventional laparoscopic TEP repair for the treatment of inguinal hernias .  To date , no other studies have compared the LESS and conventional laparoscopic TEP approaches for the treatment of  inguinal hernia  in a prospect i ve r and omized study setting . Methods For this study , 100 patients undergoing inguinal hernia repair were prospect ively r and omized into either the  LESS TEP group or the conventional laparoscopic TEP group . Pre- , intra- , and postoperative factors were recorded . The primary end point was postoperative pain . The patients were interviewed at outpatient clinics at 1 week , 3 months , and 6 months postoperatively . Results The demographic data were comparable between the two groups . The median operative time was longer in the LESS TEP group ( 63.5 min ) than in the conventional TEP group ( 50.5 min ) ( p = 0.001 ) . No conversion was performed in either group . The mean pain score 2 h postoperatively during rest was significantly higher in the conventional TEP group than in the LESS TEP group ( 3.9 vs. 2.6 ; p = 0.02 ) . The postoperative results were comparable between the groups in terms of analgesic requirements , systemic stress responses , complications , and postoperative convalescence . Conclusions The LESS TEP technique is associated with a longer operative time but offers the minor benefit of a reduction in immediate postoperative pain
The systemic inflammatory response was normalized before or on the seventh postoperative day .
Conclusions Hernia repair elicits a systemic inflammatory response characterized by an increase in CRP , IL-6 , leukocytes , neutrophils , IL-1 , IL-10 , fibrinogen , and α1-antitrypsin and a decrease in lymphocytes and albumin .
A higher inflammatory response was found after mesh repair compared with non-mesh repair and after open mesh repair compared with laparoscopic mesh repair
Purpose All surgical procedures elicit a complex systemic inflammatory response effectuated and modulated by cytokines .
The purpose of this systematic review was to present an overview of the inflammatory response and the serum markers associated with hernia repair and to compare the response between patients treated with and without mesh .