Interventions that included ET and PA counseling during PR were effective strategies to improve PA in COPD
BACKGROUND Physical inactivity is associated with poor outcomes in COPD , and as a result , interventions to improve physical activity ( PA ) are a current research focus .
However , many trials have been small and inconclusive .
OBJECTIVE The aim of this systematic review and meta- analysis was to study the effects of r and omized controlled trials ( RCTs ) targeting PA in COPD .
Improvement in self-reported exercise participation with the combination of tiotropium and rehabilitative exercise training in COPD patients
Background Improvements in ventilatory mechanics with tiotropium increases exercise tolerance during pulmonary rehabilitation . We wondered whether tiotropium also increased physical activities outside of pulmonary rehabilitation . Methods COPD patients participating in 8 weeks of pulmonary rehabilitation were studied in a r and omized , double-blind , placebo-controlled trial of tiotropium 18 μg daily ( tiotropium = 47 , placebo = 44 ) . Study drug was administered for 5 weeks prior to , 8 weeks during , and 12 weeks following pulmonary rehabilitation . Patients completed a question naire documenting participation in pre-defined activities outside of pulmonary rehabilitation during the 2 weeks prior to each visit . Patients who su bmi tted an activity question naire at week 4 and on at least one subsequent visit were included in the analysis . For each patient , the number of sessions was multiplied with the duration of each activity and then summed to give overall activity duration . Results Patients ( n = 46 ) had mean age of 67 years , mean baseline FEV1 of 0.84 L ( 33 % predicted ) . Mean ( SE ) increase in duration of activities ( minutes during 2 weeks prior to each visit ) from week 4 ( prior to PR ) to week 13 ( end of PR ) was 145 ( 84 ) minutes with tiotropium and 66 ( 96 ) minutes with placebo . The increase from week 4 to week 25 ( end of follow-up ) was 262 ( 96 ) and 60 ( 93 ) minutes for the respective groups . Increases in activity duration from week 4 to weeks 17 , 21 , and 25 were statistically significant with tiotropium . No statistical differences over time were observed within the placebo-treated group and differences between groups were not significant . Conclusions Tiotropium appears to amplify the effectiveness of pulmonary rehabilitation as seen by increases in patient self-reported participation in physical activities
Interventions that included ET and PA counseling during PR were effective strategies to improve PA in COPD
BACKGROUND Physical inactivity is associated with poor outcomes in COPD , and as a result , interventions to improve physical activity ( PA ) are a current research focus .
However , many trials have been small and inconclusive .
OBJECTIVE The aim of this systematic review and meta- analysis was to study the effects of r and omized controlled trials ( RCTs ) targeting PA in COPD .