Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Role of Prophylactic Antibiotics in Laparoscopic Cholecystectomy.
BACKGROUND Antibiotic prophylaxis is routinely administered in laparoscopic cholecystetomy but its role is debatable . METHODS From January 2004 to August 2008 , 417 patients were r and omized into 208 in antibiotic group ( AG ) and 209 in non antibiotic group ( NAG ) . AG received one dose each of injection ciprofloxacin ( 200 mg ) and metronidazole ( 500 mg ) preoperatively . NAG was given only intravenous fluids . Besides routine care , all underwent abdominal sonography and liver function tests at least once during the 30 postoperative days . RESULT Age , sex and co-morbidity distribution were similar in both the groups . One patient who was on weekly 5 mg methotraxate ( NAG ) had erythema around umbilical port . Other three having umbilical discharge recovered without antibiotics . Nine patients had subhepatic collection ( 5 AG and 4 NAG ) . One from NAG underwent re-laparoscopy and drainage . Ten patients had fever . Two from AG had basal lung collapse and were given antibiotics . CONCLUSION Antibiotic prophylaxis is not needed for laparoscopic cholecystectomy
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .