Conclusion Although , serum 25(OH)D concentrations after supplementation reached sufficiency was observed , muscle strength did not significantly improve at this point of current meta- analysis .
Background The purpose of this systematic review and meta- analysis is to investigate the effects of vitamin D3 supplementation on skeletal muscle strength in athletes .
Vitamin D3 supplements or vitamin D3 fortified foods always have cl aims for bringing people health benefits including bone and muscle health .
An up-to- date rigorous systematic review and meta- analysis is important to better underst and the effect of vitamin D3 supplementation on muscle strength .
The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletes
Abstract Heavy training is associated with increased respiratory infection risk and antimicrobial proteins are important in defence against oral and respiratory tract infections . We examined the effect of 14 weeks of vitamin D3 supplementation ( 5000 IU/day ) on the resting plasma cathelicidin concentration and the salivary secretion rates of secretory immunoglobulin A ( SIgA ) , cathelicidin , lactoferrin and lysozyme in athletes during a winter training period .  Blood and saliva were obtained at the start of the study from 39 healthy men who were r and omly allocated to vitamin D3 supplement or placebo .  Blood sample s were also collected at the end of the study ; saliva sample s were collected after 7 and 14 weeks . Plasma total 25(OH)D concentration increased by 130 % in the vitamin D3 group and decreased by 43 % in the placebo group ( both P = 0.001 ) . The percentage change of plasma cathelicidin concentration in the vitamin D3 group was higher than in the placebo group ( P = 0.025 ) . Only in the vitamin D3 group , the saliva SIgA and cathelicidin secretion rates increased over time ( both P = 0.03 ) . A daily 5000 IU vitamin D3 supplement has a beneficial effect in up-regulating the expression of SIgA and cathelicidin in athletes during a winter training period , which could improve resistance to respiratory infections
Conclusion Although , serum 25(OH)D concentrations after supplementation reached sufficiency was observed , muscle strength did not significantly improve at this point of current meta- analysis .
Background The purpose of this systematic review and meta- analysis is to investigate the effects of vitamin D3 supplementation on skeletal muscle strength in athletes .
Vitamin D3 supplements or vitamin D3 fortified foods always have cl aims for bringing people health benefits including bone and muscle health .
An up-to- date rigorous systematic review and meta- analysis is important to better underst and the effect of vitamin D3 supplementation on muscle strength .