CLINICAL IMPLICATION S Only SCORAD , EASI , and POEM currently perform adequately .
BACKGROUND Valid and reliable outcome measurements are a prerequisite for evidence -based practice .
The comparative validity and reliability of outcome measurements for assessing atopic eczema ( AE ) severity is unclear .
OBJECTIVE We sought to assess the validity , reliability , sensitivity to change , and ease of use of outcome measurements for AE .
We also sought to give recommendations on which outcomes to use in clinical research and for clinical monitoring .
Disease severity and associated family impact in childhood atopic dermatitis
Aim : To examine the association between childhood atopic dermatitis ( AD ) severity and family impact at baseline and after an intervention by a physician specialist , using vali date d measures of both severity and family impact . Methods : Cross sectional self administered survey of parent – caregivers of 49 r and omly selected children with AD ; 35 parents were available for follow up .  Family impact was measured using a modified AD Family Impact Scale completed by the parent – caregiver . The child ’s disease severity was measured using both the investigator ’s assessment via the Eczema Area and Severity Index ( EASI ) and the caregiver ’s assessment via the recently vali date d Self Assessment Eczema Area and Severity Index ( SA-EASI ) . Results : The parent – caregiver ’s assessment of severity of the child was the most significant correlate of the family impact of the child ’s AD ( p = 0.65 at baseline and p = 0.38 at follow up ) . In multivariate regression models , the parent – caregiver ’s estimate of severity remained the single strongest predictor of family impact before and after receipt of dermatologist care , as well as the difference in impact between pre and post-dermatologist care . Conclusions : There is evidence to support the ability of parent – caregivers of children with AD to accurately determine severity of their child ’s AD ; perceived severity is the driver of the family impact of this condition . Treatment of a child by a physician specialist is associated with reductions in both perceived severity , as well as family impact of this condition
CLINICAL IMPLICATION S Only SCORAD , EASI , and POEM currently perform adequately .
BACKGROUND Valid and reliable outcome measurements are a prerequisite for evidence -based practice .
The comparative validity and reliability of outcome measurements for assessing atopic eczema ( AE ) severity is unclear .
OBJECTIVE We sought to assess the validity , reliability , sensitivity to change , and ease of use of outcome measurements for AE .
We also sought to give recommendations on which outcomes to use in clinical research and for clinical monitoring .