Conclusions : Antibiotic prophylaxis did confer a reduction in cases of symptomatic and asymptomatic bacteriuria but the NNT were high .
Introduction : The role of antibiotic prophylaxis for routine flexible cystoscopy ( FC ) is not clear due to the varying practice s of individual clinicians .
There are no formal guidelines , and this may be due to a lack of formal summary of the data .
[Antimicrobial prophylaxis in urethrocystoscopy. Comparative study].
Instrumentation of lower urinary tract is a predisposing factor for the development of  urinary infection .  Incidence of infective complications following urethrocystoscopy has been evaluated in a multicenter , prospect i ve , comparative and r and omized study in 2,284 patients , who had a previous negative urine culture . Patients were r and omized into two groups : one to be used as control and the other one to received antimicrobial prophylaxis prior to instrumentation ( ceftriazone , 1 gr intramuscular ) . Clinical and microbiological responses were evaluated at 48 - 72 hours and 4 weeks after cystoscopy . Symptomatic bacteriuria was observed in 10.2 % of patients in the control group and in 2.5 % in the prophylaxis group ( p < 0.000 ) ; asymptomatic bacteriuria in 3.02 % and 1.52 % ( p > 0.05 ) and irritative syndrome with sterile urine in 2.93 % and 2.60 % ( p > 0.05 ) , respectively . Thus , the use of prophylaxis reduced the incidence of infective complications in these patients
Conclusions : Antibiotic prophylaxis did confer a reduction in cases of symptomatic and asymptomatic bacteriuria but the NNT were high .
Introduction : The role of antibiotic prophylaxis for routine flexible cystoscopy ( FC ) is not clear due to the varying practice s of individual clinicians .
There are no formal guidelines , and this may be due to a lack of formal summary of the data .