Conclusion We present clear evidence for the benefit of probiotics and synbiotics supplementation  for liver steatosis , liver enzymes , lipid profiles and liver stiffness in patients with NAFLD
Background and Aim Extensive epidemiological evidence suggests that nonalcoholic fatty liver disease ( NAFLD ) is the primary chronic liver disease worldwide .
However , some studies have showed conflicting results on the effects of probiotics and synbiotics supplementation .
Therefore , we conducted a systematic review and meta- analysis to investigate the effectiveness of the supplementation in subjects with NAFLD .
Probiotic Soy Milk Consumption and Renal Function Among Type 2 Diabetic Patients with Nephropathy: a Randomized Controlled Clinical Trial
Diabetic nephropathy ( DN ) is one the most important complications of diabetes leading to end-stage renal disease . Dietary approaches have been considered to control of the kidney function deterioration among these patients . The aim of the present study was to determine the effects of fortified soy milk with Lactobacillus plantarum A7 on renal function biomarkers in type 2 DN patients . Forty-eight DN subjects were attended to this parallel r and omized trial study . Participants were r and omly assigned to consume a diet containing 200 mL/day probiotic soy milk in intervention group or soy milk in the control condition for 8 weeks . An inflammatory adipokine — Progranulin ( PGRN ) , a cytokine receptor-soluble tumor necrosis factor receptor 1 ( sTNFR1 ) , and serum levels of Neutrophil gelatinase-associated lipocalin ( NGAL ) and cystatin C ( Cys-C ) as the new renal function biomarkers were measured after 8 weeks of intervention according to the st and ard protocol . Our analysis showed that consumption of probiotic soy milk result ed in a significant reduction in the Cys-C and PGRN levels compared with the soy milk ( P = 0.01 ) in the final adjusted model . In addition , after adjustment for age , weight , and energy intake , a marginally significant in the NGAL level was seen between two groups ( P = 0.05 ) . However , there was no significant differences on the sTNFR1concenteration between two groups ( P = 0.06 ) . Overall , intake of probiotic soy milk may have a beneficial effect on the renal function in patients with DN
Conclusion We present clear evidence for the benefit of probiotics and synbiotics supplementation  for liver steatosis , liver enzymes , lipid profiles and liver stiffness in patients with NAFLD
Background and Aim Extensive epidemiological evidence suggests that nonalcoholic fatty liver disease ( NAFLD ) is the primary chronic liver disease worldwide .
However , some studies have showed conflicting results on the effects of probiotics and synbiotics supplementation .
Therefore , we conducted a systematic review and meta- analysis to investigate the effectiveness of the supplementation in subjects with NAFLD .