RESULTS The present study indicated that the efficacy of various fiber supplements on losing weight is variable .
Several mechanisms related to physicochemical properties of fibers such as solubility , fermentability and viscosity rates can be involved in their anti-obesity effects .
Dextrin , Mannan ( gum Arabic ) and pectin-rich fiber ( lupin kernel ) with no dietary interventions indicated a reduction in body weight and energy intake , while from clinical point of view , their effects were not considerable .
Overall , findings indicated that the efficacy of fiber supplements on obesity management is dependent on their contents and physicochemical properties .
It seems that fiber supplements with no weight-loss interventions did not have considerable antiobesity effects .
BACKGROUND Previous trials have reported beneficial effects of isolated and complex fiber supplements in obesity treatment .
However , recommending fiber supplements in obese subjects remains controversial .
To the best of our knowledge , no systematic review has up date d the data on the effects of fiber supplements on obesity since 2010 and the need exists for a systematic review on this topic .
Accordingly , a systematic review was undertaken to summarize the efficacy of different types of fiber supplements as a complementary treatment for weight management .
The Therapeutic Potential of Resistant Starch in Modulation of Insulin Resistance, Endotoxemia, Oxidative Stress and Antioxidant Biomarkers in Women with Type 2 Diabetes: A Randomized Controlled Clinical Trial
Aims : This trial aims to determine the effects of resistant starch ( RS ) subtype 2 ( RS2 ) on glycemic status , metabolic endotoxemia and markers of oxidative stress . Methods : A r and omized , controlled , parallel-group clinical trial group of 56 females with type 2 diabetes mellitus ( T2DM ) was divided to 2 groups . The intervention group ( n = 28 ) and control group ( n = 28 ) received 10 g/day RS2 or placebo for 8 weeks , respectively . Fasting blood sample s were taken to determine glycemic status , endotoxin , high sensitivity C-reactive protein ( hs-CRP ) , malondialdehyde ( MDA ) , total antioxidant capacity ( TAC ) , antioxidant enzymes concentrations as well as uric acid at baseline and after the intervention . Results : After 8 weeks , RS2 caused a significant decrease in the levels of MDA ( -34.10 % ) , glycosylated hemoglobin ( -9.40 % ) , insulin ( -29.36 % ) , homeostasis model of insulin resistance ( -32.85 % ) and endotoxin ( -25.00 % ) , a significant increase in TAC ( 18.10 % ) and glutathione peroxidase ( 11.60 % ) as compared with control . No significant changes were observed in fasting plasma glucose , quantitative insulin sensitivity check index , hs-CRP , superoxide dismutase , catalase and uric acid in the RS2 group as compared with the control group . Conclusion : Supplementation with RS2 may be improved glycemic status , endotoxemia and markers of oxidative stress in patients with T2DM
RESULTS The present study indicated that the efficacy of various fiber supplements on losing weight is variable .
Several mechanisms related to physicochemical properties of fibers such as solubility , fermentability and viscosity rates can be involved in their anti-obesity effects .
Dextrin , Mannan ( gum Arabic ) and pectin-rich fiber ( lupin kernel ) with no dietary interventions indicated a reduction in body weight and energy intake , while from clinical point of view , their effects were not considerable .
Overall , findings indicated that the efficacy of fiber supplements on obesity management is dependent on their contents and physicochemical properties .
It seems that fiber supplements with no weight-loss interventions did not have considerable antiobesity effects .
BACKGROUND Previous trials have reported beneficial effects of isolated and complex fiber supplements in obesity treatment .
However , recommending fiber supplements in obese subjects remains controversial .
To the best of our knowledge , no systematic review has up date d the data on the effects of fiber supplements on obesity since 2010 and the need exists for a systematic review on this topic .
Accordingly , a systematic review was undertaken to summarize the efficacy of different types of fiber supplements as a complementary treatment for weight management .