The results of the present meta- analysis show that probiotic supplementation  prevents infantile eczema , thus suggesting a new potential indication for probiotic use in pregnancy and infancy
Growing evidence underlines the pivotal role of infant gut colonization in the development of the immune system .
The possibility to modify gut colonization through probiotic supplementation in childhood might prevent atopic diseases .
The aim of the present systematic review and meta- analysis was to evaluate the effect of probiotic supplementation during pregnancy and early infancy in preventing atopic diseases .
Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?
The role of probiotics in prevention of  allergic disease  is still not clear ; efficacy may depend on the timing , dose , duration , and specific probiotic used . Using a double‐blind r and omized placebo‐controlled trial ( Australian New Zeal and Clinical Trials Registry : ACTRN12607000518460 ) , we have shown that in a high‐risk birth cohort , maternal supplementation from 35 weeks gestation until 6 months if breastfeeding and infant supplementation from birth until 2 years with Lactobacillus rhamnosus HN001 ( HN001 ) ( 6 × 109 cfu/day ) halved the cumulative prevalence of eczema at 2 and 4 years . Bifidobacterium animalis subsp lactis HN019 ( HN019 ) ( 9 × 109 cfu/day ) had no significant effect
The results of the present meta- analysis show that probiotic supplementation  prevents infantile eczema , thus suggesting a new potential indication for probiotic use in pregnancy and infancy
Growing evidence underlines the pivotal role of infant gut colonization in the development of the immune system .
The possibility to modify gut colonization through probiotic supplementation in childhood might prevent atopic diseases .
The aim of the present systematic review and meta- analysis was to evaluate the effect of probiotic supplementation during pregnancy and early infancy in preventing atopic diseases .