For blood glucose there was little difference between groups at any time point .
Objective Type 1 diabetes mellitus rates are rising worldwide .
The health benefits of physical exercise in this condition are many , but more than 60 % do not participate , mainly from fear of hypoglycemia .
This systematic review explores the effects of physical exercise modes on blood glucose levels in adults for hypoglycemia prevention .
Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin
Introduction We investigated blood glucose ( BG ) and hormone response to aerobic high-intensity interval exercise ( HIIE ) and moderate continuous exercise ( CON ) matched for mean load and duration in type 1 diabetes mellitus ( T1DM ) . Material and Methods Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below ( A ) and above ( B ) the first lactate turn point and below the second lactate turn point ( C ) on a cycle ergometer . Subjects were adjusted to ultra-long-acting insulin Degludec ( Tresiba/ Novo Nordisk , Denmark ) . Before exercise , st and ardized meals were administered , and short-acting insulin dose was reduced by 25 % ( A ) , 50 % ( B ) , and 75 % ( C ) dependent on mean exercise intensity . During exercise , BG , adrenaline , noradrenaline , dopamine , cortisol , glucagon , and insulin-like growth factor-1 , blood lactate , heart rate , and gas exchange variables were measured . For 24 h after exercise , interstitial glucose was measured by continuous glucose monitoring system . Results BG decrease during HIIE was significantly smaller for B ( p = 0.024 ) and tended to be smaller for A and C compared to CON . No differences were found for post-exercise interstitial glucose , acute hormone response , and carbohydrate utilization between HIIE and CON for A , B , and C. In HIIE , blood lactate for A ( p = 0.006 ) and B ( p = 0.004 ) and respiratory exchange ratio for A ( p = 0.003 ) and B ( p = 0.003 ) were significantly higher compared to CON but not for C. Conclusion Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our method ological approach for exercise prescription . HIIE led to a smaller BG decrease compared to CON , although both exercises modes were matched for mean load and duration , even despite markedly higher peak workloads applied in HIIE . Therefore , HIIE and CON could be safely performed in T1DM . Trial Registration Clinical Trials.gov NCT02075567 http://www . clinical
For blood glucose there was little difference between groups at any time point .
Objective Type 1 diabetes mellitus rates are rising worldwide .
The health benefits of physical exercise in this condition are many , but more than 60 % do not participate , mainly from fear of hypoglycemia .
This systematic review explores the effects of physical exercise modes on blood glucose levels in adults for hypoglycemia prevention .