The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .
Effect of beta-carotene supplementation on the concentrations and distribution of carotenoids, vitamin E, vitamin A, and cholesterol in plasma lipoprotein and non-lipoprotein fractions in healthy older women.
OBJECTIVE We studied the effect of beta-carotene supplementation on the concentrations and distribution in plasma lipoprotein and non-lipoprotein fractions of carotenoids , alpha-tocopherol , retinol , and cholesterol . METHODS Ten women ingested either 90 mg of beta-carotene or placebo daily for 3 weeks while residing in their homes and eating their usual meals . Carotenoids ( beta-carotene , lycopene , lutein/zeaxanthin ) , retinol , alpha-tocopherol , and cholesterol were measured in plasma lipoprotein and non-lipoprotein fractions before and after treatment . RESULTS In the beta-carotene-supplemented group , total plasma beta-carotene increased 14-fold from 0.48 + /- 0.13 to 6.83 + /- 2.12 mumol/L ( p = 0.04 ) . Although the greatest increase in beta-carotene was in low-density-lipoproteins ( LDL ) , the magnitude of increase was similar in LDL , high-density-lipoproteins ( HDL ) , and very-low-density-lipoproteins ( VLDL ) . Thus , the relative distribution of beta-carotene in lipoproteins was unchanged : approximately 71 % was in LDL , approximately 15 % in HDL and approximately 12 % in VLDL , before and after beta-carotene supplementation . There were no changes in amounts and distribution in lipoproteins of the other carotenoids , alpha-tocopherol , and cholesterol . There was no change in the amount of retinol in lipoprotein-deficient plasma . There were no changes in total plasma triglycerides . Significant positive correlations were found between LDL- or VLDL-cholesterol and alpha-tocopherol in LDL or VLDL , respectively ; between LDL- or VLDL-cholesterol and lutein/zeaxanthin in LDL or VLDL , respectively ; and between HDL-cholesterol and beta-carotene in HDL . CONCLUSIONS beta-Carotene supplementation ( 90 mg/day for 3 weeks ) in healthy older women results in an enrichment of all plasma lipoprotein fractions with beta-carotene , but does not alter the relative distribution of beta-carotene in lipoproteins . beta-Carotene supplementation has no effect on the amounts and relative distribution of lycopene , lutein/zeaxanthin , and alpha-tocopherol in lipoproteins , or of retinol in the non-lipoprotein fraction of plasma . Short-term beta-carotene supplementation has no effect on the concentrations of plasma total triglycerides , total cholesterol , HDL- , LDL- , and VLDL-cholesterol
The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .