Results of this review support the presence of sensory modulation problems in preterm children .
Sensory modulation problems may play a key role in underst and ing neurocognitive and behavioral sequelae in preterm children .
Some support is found for a dose-response relationship between both white matter brain injury and length of NICU stay and sensory modulation problems
BACKGROUND Neurodevelopmental sequelae in preterm born children are generally considered to result from cerebral white matter damage and noxious effects of environmental factors in the neonatal intensive care unit ( NICU ) .
Cerebral white matter damage is associated with sensory processing problems in terms of registration , integration and modulation .
However , research into sensory processing problems and , in particular , sensory modulation problems , is scarce in preterm children .
AIM This review aims to integrate available evidence on sensory modulation problems in preterm infants and children ( < 37 weeks of gestation ) and their association with neurocognitive and behavioral problems .
Neonatal intensive care unit stress is associated with brain development in preterm infants
Although many perinatal factors have been linked to adverse neurodevelopmental outcomes in very premature infants , much of the variation in outcome remains unexplained . The impact on brain development of 1 potential factor , exposure to stressors in the neonatal intensive care unit , has not yet been studied in a systematic , prospect i ve manner
Results of this review support the presence of sensory modulation problems in preterm children .
Sensory modulation problems may play a key role in underst and ing neurocognitive and behavioral sequelae in preterm children .
Some support is found for a dose-response relationship between both white matter brain injury and length of NICU stay and sensory modulation problems
BACKGROUND Neurodevelopmental sequelae in preterm born children are generally considered to result from cerebral white matter damage and noxious effects of environmental factors in the neonatal intensive care unit ( NICU ) .
Cerebral white matter damage is associated with sensory processing problems in terms of registration , integration and modulation .
However , research into sensory processing problems and , in particular , sensory modulation problems , is scarce in preterm children .
AIM This review aims to integrate available evidence on sensory modulation problems in preterm infants and children ( < 37 weeks of gestation ) and their association with neurocognitive and behavioral problems .