Weight loss diet beneficially affects blood adiponectin concentrations .
Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass .
However , the magnitude of the effect of low calorie diet on adiponectin concentrations remains unknown .
The present study was aim ed to conduct a systematic review and meta- analysis on clinical trials that access the effect of low calorie diet on adiponectin concentration .
Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction.
Calorie restriction ( CR ) and alternate-day fasting ( ADF ) beneficially affect several aspects of adipose tissue physiology , but direct comparisons between regimens have yet to be performed . The present study evaluated the effects of ADF versus CR on body fat distribution and circulating adiponectin levels and examined the kinetic mechanisms that underlie changes in fat distribution . Thirty female C57BL/6J mice were r and omized to one of five groups for 4 weeks : ( a ) CR-25 % ( 25 % energy restriction daily ) , ( b ) ADF-75 % ( 75 % restriction on fast day ) , ( c ) ADF-85 % ( 85 % restriction on fast day ) , ( d ) ADF-100 % ( 100 % restriction on fast day ) and ( e ) control ( ad libitum fed ) .  Body weights of the CR mice were lower than that of the ADF and control groups posttreatment . After 4 weeks of diet , the proportion of visceral fat decreased ( P<.001 ) and the proportion of subcutaneous fat increased ( P<.001 ) similarly in ADF and CR animals . Adiponectin increased ( P<.05 ) by 62 - 86 % in the ADF groups and by 69 % in the CR group . Triglyceride ( TG ) synthesis and de novo lipogenesis were augmented ( P<.05 ) in the subcutaneous fat pad of ADF and CR animals , relative to control . No differences in net lipolysis were observed , result ing in greater TG accumulation in the subcutaneous fat pad , with a shift in the ratio of TG between depots . These findings indicate that ADF ( both modified and true ) produces similar beneficial modulations in body fat distribution and adiponectin levels as daily CR
Weight loss diet beneficially affects blood adiponectin concentrations .
Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass .
However , the magnitude of the effect of low calorie diet on adiponectin concentrations remains unknown .
The present study was aim ed to conduct a systematic review and meta- analysis on clinical trials that access the effect of low calorie diet on adiponectin concentration .