In older people with osteoporosis , higher protein intake ( ≥ 0.8-g/kg body weight/day , i.e. , above the current RDA ) is associated with higher BMD , a slower rate of bone loss , and reduced risk of hip fracture , provided that dietary calcium intakes are adequate .
Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels , together with an increase in IGF-I and a decrease in PTH .
There is no evidence that diet-derived acid load is deleterious for bone health .
Thus , insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly .
A summary of systematic review s and meta-analyses addressing the benefits and risks of dietary protein intakes  for  bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk , provided calcium intakes are adequate .
Several systematic review s and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults .
Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone .
Variation in protein intakes within the “ normal ” range accounts for 2–4 % of BMD variance in adults .
Dietary acid load, kidney function, osteoporosis, and risk of fractures in elderly men and women
Summary Because kidney dysfunction reduces the ability to excrete dietary acid excess , we hypothesized that underlying kidney function may have confounded the mixed studies linking dietary acid load with the risk of osteoporosis and fractures in the community . In a relatively large survey of elderly men and women , we report that dietary acid load did neither associate with DEXA-estimated bone mineral density nor with fracture risk . Underlying kidney function did not modify these null findings . Our results do not support the dietary acid-base hypothesis of bone loss . Introduction Impaired renal function reduces the ability to excrete dietary acid excess . We here investigate the association between dietary acid load and bone mineral density ( BMD ) , osteoporosis , and fracture risk by renal function status . Methods An observational study was conducted in 861 community-dwelling 70-year-old men and women ( 49 % men ) with complete dietary data from the Prospect i ve Investigation of the Vasculature in Uppsala Seniors ( PIVUS ) . The exposure was dietary acid load as estimated from 7-day food records by the net endogenous acid production ( NEAP ) and potential renal acid load ( PRAL ) algorithms . Renal function assessed by cystatin C estimated glomerular filtration rate was reduced in 21 % of the individuals . Study outcomes were BMD and osteoporosis state ( assessed by DEXA ) and time to fracture ( median follow-up of 9.2 years ) . Results In cross-section , dietary acid load had no significant associations with BMD or with the diagnosis of osteoporosis . During follow-up , 131 fractures were vali date d. Neither NEAP ( adjusted hazard ratios ( HR ) ( 95 % confidence interval ( CI ) ) , 1.01 ( 0.85–1.21 ) , per 1 SD increment ) nor PRAL ( adjusted HR ( 95 % CI ) , 1.07 ( 0.88–1.30 ) , per 1 SD increment ) associated with fracture risk . Further multivariate adjustment for kidney function or stratification by the presence of kidney disease did not modify these null associations . Conclusions The hypothesis that dietary acid load associates with reduced BMD or increased fracture risk was not supported by this study in community-dwelling elderly individuals . Renal function did not influence on this null finding
In older people with osteoporosis , higher protein intake ( ≥ 0.8-g/kg body weight/day , i.e. , above the current RDA ) is associated with higher BMD , a slower rate of bone loss , and reduced risk of hip fracture , provided that dietary calcium intakes are adequate .
Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels , together with an increase in IGF-I and a decrease in PTH .
There is no evidence that diet-derived acid load is deleterious for bone health .
Thus , insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly .
A summary of systematic review s and meta-analyses addressing the benefits and risks of dietary protein intakes  for  bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk , provided calcium intakes are adequate .
Several systematic review s and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults .
Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone .
Variation in protein intakes within the “ normal ” range accounts for 2–4 % of BMD variance in adults .