“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .
Effects of Xuezhikang (血脂康) and pravastatin on circulating endothelial progenitor cells in patients with essential hypertension
Objective To investigate the impacts of Xuezhikang ( 血脂康 , XZK ) or pravastatin combined with antihypertensive drugs on circulating endothelial progenitor cells ( CEPCs ) in essential hypertensive ( EH ) patients . Methods Eighty-eight EH patients were enrolled into the study and r and omly assigned to the antihypertensive drug treatment group ( ATH group , 29 cases ) , the pravastatin treatment group ( PRA group , 29 cases ) and the Xuezhikang treatment group ( XZK group , 30 cases ) . Patients in the 3 groups were treated with routine antihypertensive drugs . In addition , pravastatin and Xuezhikang were given to the patients in the PRA group and XZK group , respectively . After an eight-week treatment , CEPCs were counted using a laser scanning confocal microscope , and their proliferation function was evaluated by the MTT colorimetric assay and the adherent cell number was counted to estimate the adhesion function . Results After the treatment , CEPCs in the PRA group ( 116.60±5.70 ) and XZK group ( 114.40±6.55 ) was significantly higher than that in the ATH group ( 88.00±6.32 , P<0.01 ) . CEPCs proliferation capability and the adhesion function in the PRA group ( 0.406±0.016 , 33.60±4.26 ) and XZK group ( 0.415±0.018 , 34.30±3.77 ) were obviously superior to those in the ATH group ( 0.333±0.021 , P<0.01 ; 23.30±3.19 , P<0.01 ) . No significant difference was found between the pravastatin group and the XZK group . Conclusions Combined use of XZK or pravastatin with the anti-hypertensive therapy could increase the CEPCs number and improve their function in EH patients with the blood pressure controlled by antihypertensive drugs , leading to benefits independent of pressure-lowering effects
“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .