None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .
[Impact of intensive insulin therapy on surgical critically ill patients].
OBJECTIVE To evaluating the effect of different levels of blood glucose control on inflammatory response and prognosis of the patients in surgical intensive care unit ( SICU ) . METHODS One hundred and eighty-eight patients admitted to SICU were r and omly divided into three groups , blood glucose were controlled by insulin infusion . Group A ( 75 cases ) : the mean blood glucose ( MBG ) was maintained at the level of 4.4 - 6.1 mmol/L. Group B ( 75 cases ) : MBG was maintained at the level of 6.7 - 8.3 mmol/L. Group C ( 38 cases ) : MBG was maintained at the level of 10.0 - 11.1 mmol/L. Blood glucose control was achieved with an effected computerized protocol . The outcome was evaluated by days in ICU , days to wean mechanical ventilation , infection , amount of red blood cell transfusion , hospital mortality and ICU cost . RESULTS Compared with other groups , hypoglycemia ( < 3.3 mmol/L ) in Group A was significantly increased ( P < 0.05 ) . Compared with Group C , red blood cell transfusion and infection were significantly reduced in Group A and Group B ( P < 0.05 ) . Compared with Group C , days of mechanical ventilation and days in ICU in Group A were significantly reduced ( P < 0.05 ) . Hospital mortality and ICU cost were reduced in Group A compared with the other groups ( P > 0.05 ) . CONCLUSIONS To maintain blood glucose in normal range with intensive insulin therapy has potential positive impact on SICU patients ' outcome and can reduce days in ICU and ICU cost . Further correlation research is needed to determine the best levels of blood glucose in ICU patients
None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .