Evidence suggests that pragmatic diabetes prevention programs are effective .
Effectiveness varies substantially between programs but can be improved by maximizing guideline adherence .
OBJECTIVE To summarize the evidence on effectiveness of translational diabetes prevention programs , based on promoting lifestyle change to prevent type 2 diabetes in real-world setting s and to examine whether adherence to international guideline recommendations is associated with effectiveness .
Lifestyle interventions aim ed to translate evidence from previous efficacy trials of diabetes prevention into real-world intervention programs .
A New and Simple Questionnaire to Identify People at Increased Risk for Undiagnosed Diabetes
OBJECTIVE To develop a simple question naire to prospect ively identify individuals at increased risk for undiagnosed diabetes . RESEARCH DESIGN AND METHODS People with newly diagnosed diabetes ( n = 164 ) identified in the Second National Health and Nutrition Examination Survey and those with neither newly diagnosed diabetes nor a history of physician-diagnosed diabetes ( n = 3,220 ) were studied . Major historical risk factors for undiagnosed non-insulin-dependent diabetes were defined , and classification trees were developed to identify people at higher risk for previously undiagnosed diabetes . The sensitivity , specificity , and predictive value of the classification trees were described and compared with those of an existing question naire . RESULTS The selected classification tree incorporated age , sex , history of delivery of a macrosomic infant , obesity , sedentary lifestyle , and family history of diabetes . In a representative sample of the U.S. population , the sensitivity of the tree was 79 % , the specificity was 65 % , and the predictive value positive was 10 % . CONCLUSIONS This classification tree performed significantly better than an existing question naire and should serve as a simple , noninvasive , and potentially cost-effective tool for diagnosing diabetes in the
Evidence suggests that pragmatic diabetes prevention programs are effective .
Effectiveness varies substantially between programs but can be improved by maximizing guideline adherence .
OBJECTIVE To summarize the evidence on effectiveness of translational diabetes prevention programs , based on promoting lifestyle change to prevent type 2 diabetes in real-world setting s and to examine whether adherence to international guideline recommendations is associated with effectiveness .
Lifestyle interventions aim ed to translate evidence from previous efficacy trials of diabetes prevention into real-world intervention programs .