HM provided a clear protective effect against NEC , with an approximate 4 % reduction in incidence .
HM also provided a possible reduction in LOS , severe ROP and severe NEC .
Particularly for NEC , any volume of HM is better than EPTF , and the higher the dose the greater the protection .
Evidence regarding pasteurisation is inconclusive , but it appears to have no effect on some outcomes .
Improving the intake of mother ’s own milk ( MOM ) and /or donor HM results in small improvements in morbidity in this population
RANDOMISED CONTROLLED TRIAL OF EFFECT OF RAW AND HOLDER PASTEURISED HUMAN MILK AND OF FORMULA SUPPLEMENTS ON INCIDENCE OF NEONATAL INFECTION
Supplementary formula feeds inhibited the protective effect of expressed raw and pasteurised human milk in 226 high-risk neonates in a r and omised controlled trial . The infection rate in the group given pasteurised human milk and formula ( 33 % ) was significantly higher than the rates in the groups given raw human milk ( 10.5 % ) , pasteurised human milk ( 14.3 % ) , and raw human milk and formula ( 16 % ) . This accords with the impressions that some of the association of infection with artificial feeding is partly attributable to the lack of the protective effect of human milk . Heating expressed human milk to 62.5 degrees C for 30 min significantly reduces its protective effect
HM provided a clear protective effect against NEC , with an approximate 4 % reduction in incidence .
HM also provided a possible reduction in LOS , severe ROP and severe NEC .
Particularly for NEC , any volume of HM is better than EPTF , and the higher the dose the greater the protection .
Evidence regarding pasteurisation is inconclusive , but it appears to have no effect on some outcomes .
Improving the intake of mother ’s own milk ( MOM ) and /or donor HM results in small improvements in morbidity in this population