Only three multi-item and two single-item instruments were identified as being reliable and valid among pediatric cancer or HSCT patients and would therefore be appropriate to measure anxiety in this population
Purpose The primary objective was to describe anxiety measurement instruments used in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation ( HSCT )  and summarize their content and psychometric properties .
A Pilot Exploration of Symptom Trajectories in Adolescents With Cancer During Chemotherapy
Background : Chemotherapy is frequently administered in repetitive cycles . Adolescents with cancer have multiple symptoms related to chemotherapy , but knowledge of symptom trajectories across a cycle is limited . Examining trajectories over a cycle may reveal key periods to manage symptoms . Objectives : The aims of this pilot were to describe the trajectory of symptoms ( pain , sleep , appetite , nausea , fatigue ) and biological and behavioral variables ( anxiety , stress , hematologic function ) across 1 cycle and examine relationships between variables . Methods : Nine adolescents with cancer within 6 months of diagnosis participated . Data were collected by surveys , chart review , and biologic measures on days 1 and 2 of the cycle , 1 week later ( nadir ) , and day 1 of the following cycle . To evaluate the trajectory , a simple r and om-effects repeated- measures analysis was computed . Results : The significant trajectories were fatigue ( P = .003 ) , difficulty sleeping ( P = .032 ) , and nausea ( P = .04 ) . Most of the adolescents reported some anticipatory anxiety about receiving chemotherapy . Significant correlations between symptoms and biobehavioral variables included anticipatory anxiety and nausea ( r = .86 , P = .003 ) , trait anxiety and fatigue ( r = −0.82 , P < .001 ) , and stress and pain ( r = 0.78 , P = .039 ) . Conclusions : Multiple symptoms were experienced across the cycle . Three symptoms displayed significant trajectories indicating that patterns of symptoms may be anticipated . Implication s for Practice : Pilot findings suggest that monitoring symptoms , stress , and anxiety across a cycle is important , not only during chemotherapy administration , but also prior to being admitted for chemotherapy
Only three multi-item and two single-item instruments were identified as being reliable and valid among pediatric cancer or HSCT patients and would therefore be appropriate to measure anxiety in this population
Purpose The primary objective was to describe anxiety measurement instruments used in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation ( HSCT )  and summarize their content and psychometric properties .