RhGh did not consistently affect blood pressure or bone mineral density .
RhGH consistently improved quality of life ( QoL ) parameters reflected in AGHDA-scores .
Conclusion RhGH replacement in elderly subjects with GHD  decreases LDL cholesterol levels and improves QoL , but the effects on other parameters are not unequivocal .
There were no data on the efficacy and safety  of rhGH treatment in octogenarians with GHD
Context Recombinant human GH ( rhGH ) is prescribed for the treatment of adults with GH deficiency ( GHD ) .
However , conflicting data are available on the efficacy of rhGH treatment in elderly GHD patients .
Objective To assess the efficacy of rhGH treatment in elderly GHD subjects .
Body composition. Prediction of normal body potassium, body water and body fat in adults on the basis of body height, body weight and age.
In 134 males and 242 females , aged 20 - 70 years , most of them r and omly selected from population studies , the body composition was estimated from the measurements of body height ( BH ) , body weight ( BW ) , total body potassium ( TBK ) and total body water ( TBW ) . TBK was measured with isotope dilution technique using 42 K or determined as 40 K in a whole body counter .  TBW was determined with an isotope dilution technique using tritiated water , assayed in urine or plasma . From these data , body cell mass ( BCM ) , intra- and extra-cellular water ( ICW and ECW , resp . ) and body fat ( BF ) were calculated for each individual . Significant correlations were found between age versus TBK , ECW , BF and ECW/ICW ; between BW versus TBK , TBW , ECW , BF and ECW/ICW ; ( females only ) and between BH versus TBK , TBW , ECW ( females only ) and ECW/ICW . For the prediction of TBK , TBW and BF , multiple regression equations based on BW , BH and age are given . These equations are also presented diagrammatically . The problems with the methods used are considered as well as the applicability of the formulas for the calculation of BCM etc . The predictive value of the results when both TBW and TBK are used for the calculation of body composition data is discussed and compared with similar results , based on TBW or TBK only . It is concluded , that the most reliable method for calculation of BF is to estimate both TBW and TBK
RhGh did not consistently affect blood pressure or bone mineral density .
RhGH consistently improved quality of life ( QoL ) parameters reflected in AGHDA-scores .
Conclusion RhGH replacement in elderly subjects with GHD  decreases LDL cholesterol levels and improves QoL , but the effects on other parameters are not unequivocal .
There were no data on the efficacy and safety  of rhGH treatment in octogenarians with GHD
Context Recombinant human GH ( rhGH ) is prescribed for the treatment of adults with GH deficiency ( GHD ) .
However , conflicting data are available on the efficacy of rhGH treatment in elderly GHD patients .
Objective To assess the efficacy of rhGH treatment in elderly GHD subjects .