The association between poor performance on SPPB and all-cause mortality remained highly consistent independent of follow-up length , subsets of participants , geographic area , and age of the population .
Conclusions An SPPB score lower than 10 is predictive of all-cause mortality .
The systematic implementation of the SPPB in clinical practice setting s may provide useful prognostic information about the risk of all-cause mortality .
Background The Short Physical Performance Battery ( SPPB ) is a well-established tool to assess lower extremity physical performance status .
Its predictive ability for all-cause mortality has been sparsely reported , but with conflicting results in different subsets of participants .
The aim of this study was to perform a meta- analysis investigating the relationship between SPPB score and all-cause mortality  .
Effects of Mobility and Cognition on Risk of Mortality in Women in Late Life: A Prospective Study.
BACKGROUND This study examines the effects of mobility and cognition on  mortality risk in women late in life . METHODS A prospect i ve study was conducted among 1,495 women ( mean age 87.6 years ) participating in the Study of Osteoporotic Fractures Year 20 examination ( 2006 - 2008 ) .  Mobility  ( ascertained by Short Physical Performance Battery [ SPPB ] ) was categorized as poor ( SPPB 0 - 3 , n = 312 ) , intermediate ( SPPB 4 - 9 , n = 799 ) , or good ( SPPB 10 - 12 , n = 384 ) . Cognitive status ( adjudicated based on neuropsychological tests ) was classified as normal ( n = 873 ) , mild cognitive impairment ( n = 354 ) , or dementia ( n = 268 ) . Deaths ( n = 749 ) were identified from Year 20 through July 31 , 2014 ( average follow-up 4.9 years ) . RESULTS There was not strong evidence of an interaction between mobility and cognition for prediction of mortality risk ( p interaction term .16 ) . Compared to women with good mobility , mortality risks were increased among women with intermediate mobility ( hazard ratio [ HR ] 1.26 , 95 % confidence interval [ CI ] 1.02 - 1.57 ) and those with poor mobility ( HR 1.64 , 95 % CI 1.24 - 2.16 ) after consideration of cognition and other mortality risk factors . Similarly , mortality risks were higher among women with mild cognitive impairment ( HR 1.46 , 95 % CI 1.21 - 1.76 ) and those with dementia ( HR 1.88 , 95 % CI 1.54 - 2.31 ) compared to women with normal cognition after consideration of mobility and other mortality risk factors . CONCLUSIONS Among women late in life , 5-year mortality risk was substantially increased among women with deficits in mobility even after accounting for cognition and traditional prognostic indicators . Similarly , deficits in cognition were associated with increased 5-year mortality despite consideration of mobility and conventional risk factors
The association between poor performance on SPPB and all-cause mortality remained highly consistent independent of follow-up length , subsets of participants , geographic area , and age of the population .
Conclusions An SPPB score lower than 10 is predictive of all-cause mortality .
The systematic implementation of the SPPB in clinical practice setting s may provide useful prognostic information about the risk of all-cause mortality .
Background The Short Physical Performance Battery ( SPPB ) is a well-established tool to assess lower extremity physical performance status .
Its predictive ability for all-cause mortality has been sparsely reported , but with conflicting results in different subsets of participants .
The aim of this study was to perform a meta- analysis investigating the relationship between SPPB score and all-cause mortality  .