No significant difference in pulmonary function was observed between the two groups .
However , 6MWD and VO2 peak were significantly improved after exercise training .
Conclusion Preoperative exercise training may reduce PPCs for lung cancer patients .
Rehabilitation exercise strengthens muscle capacity , but does not improve impaired pulmonary function , which emphasizes the possible mechanism of the protocol design
Objectives This meta- analysis aim ed to demonstrate the impact of preoperative exercise therapy on surgical outcomes in patients with lung cancer and COPD .
Pulmonary function and muscle capacity were investigated to explore their potential links with outcome improvements after exercise .
Preoperative Maximal Oxygen Uptake and Exercise-induced Changes in Pulse Oximetry Predict Early Postoperative Respiratory Complications in Lung Cancer Patients
Background : Postoperative respiratory complications often arise in lung cancer patients after lung resection , although these are often difficult to predict . We sought to identify reliable predictors of early-onset postoperative respiratory complications in lung cancer patients who had moderate-to-severe preoperative respiratory impairment . Methods : This was a prospect i ve observational study that included 107 consecutive lung cancer patients with forced expiratory volume in 1 s < 60 % of predicted who were scheduled for thoracotomy and lung resection .  Preoperative functional assessment s included pulmonary function testing by spirometry , single breath diffusion capacity of lung for carbon monoxide , and cardiopulmonary exercise testing . Risk factors for early-onset postoperative respiratory complications that occurred within 30 days postoperatively were sought from among these pulmonary function testing and cardiopulmonary exercise testing results . Results : By multivariable logistic regression , peak oxygen uptake ( V′O2max% ; p < 0.001 ) and the transcutaneous pulse oxygen saturation difference during load exercise ( ΔSPO2 % ; p < 0.001 ) were independent predictors of postoperative respiratory complications . A receiver operating characteristic curve had an area under the curve of 0.846 for the combination of V′O2max% and ΔSPO2 % , while the area under the curve with V′O2max% only was 0.726 . From this , the probability of postoperative respiratory complications was P complication = e ( 2 . 58 − 0 . 08 V ′ O 2 max % + 0 . 56 Δ SP O 2 % ) / [ 1 + e ( 2 . 58 − 0 . 08 V ′ O 2 max % + 0 . 56 Δ SP O 2 % ) ] . Pcomplication ≥ 0.202 for postoperative respiratory complications had a sensitivity of 80.8 % and a specificity of 81.5 % . Conclusions : For lung cancer patients with forced expiratory volume in 1 s < 60 % of predicted , in addition to common preoperative tests , V′O2max% and ΔSPO2 % may be an aid for predicting early-onset postoperative respiratory complications
No significant difference in pulmonary function was observed between the two groups .
However , 6MWD and VO2 peak were significantly improved after exercise training .
Conclusion Preoperative exercise training may reduce PPCs for lung cancer patients .
Rehabilitation exercise strengthens muscle capacity , but does not improve impaired pulmonary function , which emphasizes the possible mechanism of the protocol design
Objectives This meta- analysis aim ed to demonstrate the impact of preoperative exercise therapy on surgical outcomes in patients with lung cancer and COPD .
Pulmonary function and muscle capacity were investigated to explore their potential links with outcome improvements after exercise .