Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Antimicrobial Prophylaxis with Ceftriaxone in Laparoscopic Cholecystectomy: a 7-Year Clinical Experience Involving 3,603 Patients
Summary This study is one of the first in the literature with the aim of assessing the effectiveness of antimicrobial prophylaxis with a single preoperative dose of long-acting ceftriaxone in a retrospective analysis of 3,603 patients undergoing laparoscopic cholecystectomy . All patients who underwent laparoscopic cholecystectomy between October 1990 and December 1997 were review ed . Antimicrobial prophylaxis with a single dose of ceftriaxone ( 1 g ) was given intravenously at the induction of anesthesia . Patients were closely monitored for infections until 4 weeks after surgery . Postoperative infections occurred in 44 of the 3,603 patients undergoing laparoscopic cholecystectomy , with an infection rate of 1.22 % . The infectious complications mainly comprised wound infections ( n=13 ) but also included intra-abdominal abscesses ( n=3 ) , pneumonia ( n=9 ) , urinary tract infections ( n=3 ) and other infections ( n=16 ) . The results of this retrospective and non-r and omized study , show that a single-shot regimen containing ceftriaxone may be a cost-effective measure in preventing postoperative infections in patients undergoing laparoscopic cholecystectomy
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .