The effect of ARB on the improvement of the PWV level is not superior to other types of antihypertensive agents , but ARB is superior to other types of antihypertensive agents for improving the AI level .
Overall , to improve of arterial stiffness , ARB maybe is superior to other antihypertensive agents
BACKGROUND This system review and meta- analysis was conducted to systematic ally review and analyze the clinical benefits of different antihypertensive agents in improving arterial stiffness in hypertensive patients .
Efficacy of aliskiren and valsartan in hypertensive patients with albuminuria: a randomized parallel-group study
Introduction : Blockade of the renin-angiotensin system ( RAS ) is a critical approach to the management of hypertension , especially in proteinuric patients . It is well proven that the direct renin inhibitor aliskiren shows comparable clinical efficacy to the angiotensin II receptor blocker valsartan on blood pressure control and albuminuria . However , there is only limited data on the h and -to-h and effectiveness of these two RAS blockers in improving arterial stiffness . We tested whether aliskiren or valsartan would improve arterial stiffness in hypertensive patients with albuminuria who are already on antihypertensive therapy . Material and methods : Thirty-four patients with hypertension and albuminuria < 1 g , after a wash-out period of three weeks , were r and omized to aliskiren or valsartan in a 24-week r and omized parallel-group study . Results : A nonsignificant difference in blood pressure was seen between the two treatment groups . Albuminuria was significantly reduced in both groups ( 56 % for the aliskiren group , p < 0.05 , and 38 % for the valsartan group , p < 0.05 ) . Only valsartan but not aliskiren significantly reduced carotid-femoral pulse wave velocity ( –1.1 ± 0.8 m/s ( p = 0.02 ) for valsartan and + 0.1 ± 0.7 m/s ( ns ) for aliskiren ) . Conclusion : The results of our study showed that valsartan  improves arterial stiffness to a significantly greater extent than aliskiren , despite a similar antihypertensive and antiproteinuric effect
The effect of ARB on the improvement of the PWV level is not superior to other types of antihypertensive agents , but ARB is superior to other types of antihypertensive agents for improving the AI level .
Overall , to improve of arterial stiffness , ARB maybe is superior to other antihypertensive agents
BACKGROUND This system review and meta- analysis was conducted to systematic ally review and analyze the clinical benefits of different antihypertensive agents in improving arterial stiffness in hypertensive patients .