Evidence suggests that pragmatic diabetes prevention programs are effective .
Effectiveness varies substantially between programs but can be improved by maximizing guideline adherence .
OBJECTIVE To summarize the evidence on effectiveness of translational diabetes prevention programs , based on promoting lifestyle change to prevent type 2 diabetes in real-world setting s and to examine whether adherence to international guideline recommendations is associated with effectiveness .
Lifestyle interventions aim ed to translate evidence from previous efficacy trials of diabetes prevention into real-world intervention programs .
A lifestyle intervention to reduce Type 2 diabetes risk in Dutch primary care: 2.5-year results of a randomized controlled trial.
AIMS To determine the effectiveness of a 2.5-year lifestyle intervention for Type 2 diabetes prevention in Dutch general practice compared with usual care . METHODS A r and omized controlled trial of 925 individuals at high risk for Type 2 diabetes ( FINDRISC-score ≥ 13 ) in 14 general practice s in the Netherl and s. Intervention consisted of lifestyle counselling from the nurse practitioner and the general practitioner . Usual care consisted of oral and written information at the start of the study . Study groups were compared over 2.5 years regarding changes in clinical and lifestyle measures . RESULTS Both groups showed modest changes in body weight , glucose concentrations , physical activity and dietary intake [ weight : intervention group , -0.8 ( 5.1 ) kg , usual care group , -0.4 ( 4.7 ) kg , ( P=0.69 ) ; fasting plasma glucose : intervention group , -0.17 ( 0.4 ) mmol/l , usual care group , -0.10 ( 0.5 ) mmol/l , ( P=0.10 ) ] . Differences between groups were significant only for total physical activity and fibre intake . In the intervention group , self-efficacy was significantly higher in individuals successful at losing weight compared with unsuccessful individuals . No significant differences in participant weight loss were found between general practitioners and nurse practitioners with different levels of motivation or self-efficacy . CONCLUSIONS Diabetes risk factors could significantly be reduced by lifestyle counselling in Dutch primary care . However , intervention effects above the effects attributable to usual care were modest . Higher participant self-efficacy seemed to facilitate weight loss . Lack of motivation or self-efficacy of professionals did not negatively influence participant guidance
Evidence suggests that pragmatic diabetes prevention programs are effective .
Effectiveness varies substantially between programs but can be improved by maximizing guideline adherence .
OBJECTIVE To summarize the evidence on effectiveness of translational diabetes prevention programs , based on promoting lifestyle change to prevent type 2 diabetes in real-world setting s and to examine whether adherence to international guideline recommendations is associated with effectiveness .
Lifestyle interventions aim ed to translate evidence from previous efficacy trials of diabetes prevention into real-world intervention programs .