Outcomes , such as range of motion , recurrence , and clinical success , were frequently defined , however many different definitions were used .
This systematic review summarizes the outcome reporting st and ards in Dupuytren ’s disease treatment research .
Costs for collagenase injections compared with fasciectomy in the treatment of Dupuytren's contracture: a retrospective cohort study
Objectives To compare collagenase injections and surgery ( fasciectomy ) for Dupuytren 's contracture ( DC ) regarding actual total direct treatment costs and short-term outcomes . Design Retrospective cohort study . Setting Orthopaedic department of a regional hospital in Sweden . Participants Patients aged 65 years or older with previously untreated DC of 30 ° or greater in the metacarpophalangeal ( MCP ) and /or proximal interphalangeal ( PIP ) joints of the small , ring or middle finger . The  collagenase group comprised 16 consecutive patients treated during the first 6 months following the introduction of collagenase as treatment for DC at the study centre . The controls were 16 patients r and omly selected among those operated on with fasciectomy at the same centre during the preceding 3 years . Interventions Treatment with collagenase was given during two st and ard outpatient clinic visits ( injection of 0.9 mg , distributed at multiple sites in a palpable cord , and next-day finger extension under local anaesthesia ) followed by night-time splinting . Fasciectomy was carried out in the operating room ( day surgery ) under general or regional anaesthesia using st and ard technique , followed by therapy and splinting . Primary and secondary outcome measures Actual total direct costs ( salaries of all medical personnel involved in care , medications , material s and other relevant costs ) , and total MCP and PIP extension deficit ( degrees ) measured by h and therapists at 6–12 weeks after the treatment . Results Collagenase injection required fewer hospital outpatient visits to a therapist and nurse than fasciectomy . Total treatment cost for collagenase injection was US$ 1418.04 and for fasciectomy US$ 2102.56 . The post-treatment median ( IQR ) total extension deficit was 10 ( 0–30 ) for the collagenase group and 10 ( 0–34 ) for the fasciectomy group . Conclusions Treatment of DC with one collagenase injection costs 33 % less than fasciectomy with equivalent efficacy at 6 weeks regarding reduction in contracture
Outcomes , such as range of motion , recurrence , and clinical success , were frequently defined , however many different definitions were used .
This systematic review summarizes the outcome reporting st and ards in Dupuytren ’s disease treatment research .