Subgroup analyses showed the most marked relation between sugar intakes and lipids in studies in which efforts were made to ensure an energy balance and when no difference in weight change was reported .
CONCLUSIONS Dietary sugars  influence blood pressure and serum lipids .
The relation is independent of effects of  sugars on body weight .
BACKGROUND Dietary sugars have been suggested as a cause of obesity , several chronic diseases , and a range of cardiometabolic risk factors , but there is no convincing evidence of a causal relation between sugars and risk factors other than body weight .
OBJECTIVE We conducted a systematic review and meta- analysis of r and omized controlled trials that examined effects of the modification of dietary free sugars on blood pressure and lipids .
Effects of dietary sucrose on factors influencing cholesterol gall stone formation.
Twelve subjects with radiolucent gall stones and bile supersaturated with cholesterol were studied after six weeks each on diets which contained 112 g and 16 g respectively of refined ( fibre depleted ) sucrose but which allowed free access to other foods .  Energy intake was 24.5 % higher on the high sugar diet and body weight ended 1.4 kg higher than on the  low sugar diet .  Biliary secretion rates of cholesterol , phospholipid and bile acid , measured by a perfusion technique , were similar on the two diets , as were the bile acid pool sizes measured by isotope dilution . Cholesterol saturation index of fasting ' gall bladder ' bile was 1.30 + /- 0.11 and 1.37 + /- 0.14 on high and low sugar respectively ( NS ) . Plasma triglycerides were 36 % higher and plasma high density lipoprotein cholesterol concentrations were 9 % lower on the high sugar diet . These findings indicate that over a six week period refined sugar in normally consumed amounts does not adversely affect the lipid composition of bile
Subgroup analyses showed the most marked relation between sugar intakes and lipids in studies in which efforts were made to ensure an energy balance and when no difference in weight change was reported .
CONCLUSIONS Dietary sugars  influence blood pressure and serum lipids .
The relation is independent of effects of  sugars on body weight .
BACKGROUND Dietary sugars have been suggested as a cause of obesity , several chronic diseases , and a range of cardiometabolic risk factors , but there is no convincing evidence of a causal relation between sugars and risk factors other than body weight .
OBJECTIVE We conducted a systematic review and meta- analysis of r and omized controlled trials that examined effects of the modification of dietary free sugars on blood pressure and lipids .