Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Role of prophylactic antibiotics in laparoscopic cholecystectomy and risk factors for surgical site infection: a randomized controlled trial.
BACKGROUND The aim of this clinical trial was to determine whether prophylactic antibiotics could prevent surgical site infection ( SSI ) after laparoscopic cholecystectomy and to identify any risk factors for infection . METHODS The study included 100 patients undergoing laparoscopic cholecystectomy . They were r and omized to receive either a single dose of ceftriaxone ( Group A ; n = 50 ) or physiologic saline as placebo ( Group B ; n = 50 ) after the induction of anesthesia . Patient demographics and clinical and surgical outcomes were recorded . RESULTS The incidence of SSI was similar in the two groups : 2 patients in group A and 4 patients in group B ( chi(2 ) = 0.71 ; p = 0.40 ) . None of the factors studied was associated with surgical site infection statistically , as shown by binary logistic regression analysis . CONCLUSION A single dose of prophylactic antibiotic failed to decrease the likelihood of SSI after laparoscopic cholecystectomy
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .