For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?
Interval breast cancers in the 'screening with tomosynthesis or standard mammography' (STORM) population-based trial.
BACKGROUND & METHODS The prospect i ve ' screening with tomo synthesis or st and ard mammography ' ( STORM ) trial recruited women participating in biennial breast screening in Italy ( 2011 - 2012 ) , and compared sequential screen-readings based on 2D-mammography alone or based on tomo synthesis ( integrated 2D/3D-mammography ) . The STORM trial showed that tomo synthesis screen-reading significantly increased breast cancer detection compared to 2D-mammography alone . The present study completes reporting of the trial by examining interval breast cancers ascertained at two year follow-up . RESULTS 9 interval breast cancers were identified ; the estimated interval cancer rate was 1.23/1000 screens [ 9/7292 ] ( 95%CI 0.56 to 2.34 ) or 1.24/1000 negative screens [ 9/7235 ] ( 95%CI 0.57 to 2.36 ) . In concurrently screened women who attended the same screening services and received 2D-mammography , interval cancer rate was 1.60/1000 screens [ 40/25,058 ] ( 95 % CI 1.14 to 2.17 ) or 1.61/1000 negative screens [ 40/24,922 ] ( 95 % CI 1.15 to 2.18 ) . Estimated screening sensitivity for the STORM trial was 85.5 % [ 59/69 ] ( 95%CI 75.0%-92.8 % ) , and that for 2D-mammography screening was 77.3 % [ 136/176 ] ( 95%CI 70.4%-83.2 % ) . CONCLUSION Interval breast cancer rate amongst screening participants in the STORM trial was marginally lower ( and screening sensitivity higher ) than estimates amongst 2D-screened women ; these findings should be interpreted with caution given the small number of interval cases and the sample size of the trial . Much larger screening studies , or pooled analyses , are required to examine interval cancer rates arising after breast tomo synthesis screening versus digital mammography screening
For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?