Conclusion Applying the CHERG rules , we recommend a 73 % reduction in anemia at term with daily iron ( alone ) supplementation or iron/folate ( combined ) vs. no intervention or placebo ; for inclusion in the LiST model .
Introduction Iron deficiency is the most prevalent nutrient deficiency in the world , particularly during pregnancy .
According to the literature , anemia , particularly severe anemia , is associated with increased risk of maternal mortality .
It also puts mothers at risk of multiple perinatal complications .
Numerous studies in the past have evaluated the impact of supplementation with iron and iron-folate but data regarding the efficacy and quality of evidence of these interventions are lacking .
This article aims to address the impact of iron with and without folate supplementation on maternal anemia and provides outcome specific quality according to the Child Health Epidemiology Reference Group ( CHERG ) guidelines .
Haematological response to supplements of iron and riboflavin to pregnant and lactating women in rural Gambia.
Eighty-one pregnant or lactating women living in a village in The Gambia were allocated to treatment groups to receive a daily placebo , riboflavin , ferrous sulphate or ferrous sulphate plus riboflavin . At the beginning of the study and at 3 and 6 weeks thereafter women were examined clinical ly and blood sample s collected for haematological and biochemical measurements . Pregnant women showed a wide range of response to supplement but among the lactating women an interesting pattern emerged : whereas the haematological status of the placebo group declined over 6 weeks , in the group receiving iron supplements this deterioration was reduced although not significantly . Riboflavin given in addition to iron result ed in a significant increase in circulating plasma iron and in iron stores , relative to the placebo
Conclusion Applying the CHERG rules , we recommend a 73 % reduction in anemia at term with daily iron ( alone ) supplementation or iron/folate ( combined ) vs. no intervention or placebo ; for inclusion in the LiST model .
Introduction Iron deficiency is the most prevalent nutrient deficiency in the world , particularly during pregnancy .
According to the literature , anemia , particularly severe anemia , is associated with increased risk of maternal mortality .
It also puts mothers at risk of multiple perinatal complications .
Numerous studies in the past have evaluated the impact of supplementation with iron and iron-folate but data regarding the efficacy and quality of evidence of these interventions are lacking .
This article aims to address the impact of iron with and without folate supplementation on maternal anemia and provides outcome specific quality according to the Child Health Epidemiology Reference Group ( CHERG ) guidelines .