In patients with AF and HF , rate control compared with rhythm control showed inferior risk of hospitalisation
BACKGROUND Atrial fibrillation ( AF ) is a common arrhythmia that can promote or worsen heart failure ( HF ) .
Our purpose was to compare the effects of rate and rhythm control in patients with atrial fibrillation and heart failure .
Baseline quality of life as a predictor of mortality and hospitalization in 5,025 patients with congestive heart failure. SOLVD Investigations. Studies of Left Ventricular Dysfunction Investigators.
This study examined the independent relation of health-related quality of life ( HRQL ) to mortality and congestive heart failure (CHF)-related hospitalizations  in patients with an ejection fraction of < 0.35 followed for a mean of 36.5 months . A brief HRQL question naire was administered at baseline to patients r and omized to placebo or enalapril in the Studies of Left Ventricular Dysfunction ( SOLVD ) trial . Participants had an ejection fraction of < 0.35 and either symptomatic CHF ( treatment trial , n = 2,465 ) or asymptomatic CHF ( prevention trial , n = 2,560 ) . Baseline assessment of HRQL predicted mortality and CHF-related hospitalizations in symptomatic and asymptomatic patients r and omized to enalapril and placebo treatment . Domains that were the stronger univariate predictors of mortality and CHF-related hospitalizations were activities of daily living ( relative risk [ RR ] for mortality : 1.163 , p < 0.000 ; for hospitalization : 1.215 , p < 0.000 ) , general health ( RR for mortality : 1.205 , p < 0.000 ; for hospitalization : 1.188 , p < 0.000 ) , and social functioning ( RR for mortality 1.098 , p < 0.000 ; for hospitalization : RR 1.156 , p < 0.000 ) . In the multivariate model , activities of daily living ( RR for mortality 1.41 , p < 0.000 ; for hospitalization : RR 1.43 , p < 0.002 ) , general health ( RR for mortality 1.21 , p < 0.000 ; for hospitalization RR 1.16 , p < 0.013 ) and heart failure symptoms ( RR for mortality 1.02 , p < 0.025 ; for hospitalization RR 1.03 , p < 0.004 ) were found to be independent risk factors . HRQL independently predicted mortality and CHF-related hospitalizations after adjustment for ejection fraction , age , treatment , and New York Heart Association classification in patients with an ejection fraction of < 0.35 , r and omized to enalapril and placebo treatment . HRQL provides additional clinical information regarding disease course and outcome that is not captured by traditional indexes of clinical status
In patients with AF and HF , rate control compared with rhythm control showed inferior risk of hospitalisation
BACKGROUND Atrial fibrillation ( AF ) is a common arrhythmia that can promote or worsen heart failure ( HF ) .
Our purpose was to compare the effects of rate and rhythm control in patients with atrial fibrillation and heart failure .