Method ological factors affecting 6MWD include track length , encouragement , supplemental oxygen and walking aids .
Supplemental oxygen also affects ISWT and ESWT performance .
Responsiveness was moderate to high for all tests , with greater responsiveness to interventions that included exercise training .
The findings of this review demonstrate that the 6MWT , ISWT and ESWT are robust tests of functional exercise capacity in adults with chronic respiratory disease
This systematic review examined the measurement properties of the 6-min walk test ( 6MWT ) , incremental shuttle walk test ( ISWT ) and endurance shuttle walk test ( ESWT ) in adults with chronic respiratory disease .
The relationship of the 6-min walk test to maximal oxygen consumption in transplant candidates with end-stage lung disease.
STUDY OBJECTIVE To assess the relationship of distance ambulated during the 6-min walk test ( 6'WT ) to maximal oxygen consumption ( VO2 max ) . DESIGN Multivariate analysis of patient characteristics to VO2 max . SETTING Pre-lung transplant evaluation . PATIENTS 60 patients ( 22 men , 38 women ; mean age , 44 years ) with end-stage lung disease ( mean FEV1 and forced vital capacity of 0.97 and 1.93 , respectively ) . MEASUREMENTS AND RESULTS The 6'WT was performed on a level hallway surface , and VO2 max was obtained during maximal cycle ergometry exercise testing with respiratory gas analysis . Multivariate analysis of patient characteristics ( age , sex , weight , FEV1 , FVC , diffusing capacity for carbon monoxide ( DCO ) ,  6'WT distance ambulated  , number of rests per 6'WT  , and the  maximal heart rate , blood pressure , rate-pressure product , respiratory rate , oxygen saturation , rating of perceived exertion , and amount of supplemental oxygen  used during the 6'WT ) was performed on two groups of 30 patients each ( group A or B ) who were r and omly assigned to either group by a process of r and om selection using a computer-generated r and om numbers program . Distance ambulated was the strongest independent predictor of VO2 max ( r = 0.73 ; p < 0.0001 ) in both groups , and adding age , weight , and pulmonary function test results ( FVC , FEV1 , and DCO ) to the regression equation increased the correlation coefficient to 0.83 . Because of the significant correlation of distance ambulated during the 6'WT to VO2 max , the prediction equation obtained from the multivariate analysis of group A , VO2 max = 0.006 x distance ( feet ) + 3.38 , was used to estimate the VO2 max of the group B patients . No significant difference was observed between the estimated ( x + /- SD = 8.9 + /- 2.4 mL/kg/min ) and observed ( x + /- SD = 9.4 + /- 3.8 mL/kg/min ) VO2 max ( mean difference , 0.5 mL/kg/min ; SD of the difference = 2.88 ) . CONCLUSIONS The distance ambulated during a 6'WT can predict VO2 max in patients with end-stage lung disease . The addition of several patient characteristics can increase the ability to predict VO2 max and account for more of the variability . Such information is valuable when assessing patient response to therapeutic intervention if respiratory gas analysis is unavailable or impractical
Method ological factors affecting 6MWD include track length , encouragement , supplemental oxygen and walking aids .
Supplemental oxygen also affects ISWT and ESWT performance .
Responsiveness was moderate to high for all tests , with greater responsiveness to interventions that included exercise training .
The findings of this review demonstrate that the 6MWT , ISWT and ESWT are robust tests of functional exercise capacity in adults with chronic respiratory disease
This systematic review examined the measurement properties of the 6-min walk test ( 6MWT ) , incremental shuttle walk test ( ISWT ) and endurance shuttle walk test ( ESWT ) in adults with chronic respiratory disease .