Evidence on harms was limited , but direct harms seemed minimal ( for resting ECG ) or small ( for exercise ECG ) .
BACKGROUND Coronary heart disease is the leading cause of death in adults .
Screening for abnormalities by using resting or exercise electrocardiography ( ECG ) might help identify persons who would benefit from interventions to reduce cardiovascular risk .
PURPOSE To up date the 2004 U.S. Preventive Services Task Force evidence review on screening for  resting or exercise ECG abnormalities in asymptomatic adults .
Long-term prognostic significance of isolated minor electrocardiographic T-wave abnormalities in middle-aged men free of clinical cardiovascular disease (The Multiple Risk Factor Intervention Trial [MRFIT]).
1996;3:213–219 . 5 . Rubins HB , Robins SJ , Collins D , Fye CL , And erson JW , Elam MB , Faas FH , Linares E , Schaefer EJ , Schectman G , Wilt TJ , Wittes J. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol . Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group . N Engl J Med 1999;341 : 410 –418 . 6 . Bloomfield Rubins H , Davenport J , Babikian V , Brass LM , Collins D , Wexler L , Wagner S , Papademetriou V , Rutan G , Robins SJ . Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol : the Veterans Affairs HDL Intervention Trial ( VA-HIT ) . Circulation 2001;103:2828– 2833 . 7 . Frick MH , Elo O , Haapa K , Heinonen OP , Heinsalmi P , Helo P , Huttunen JK , Kaitaniemi P , Koskinen P , Manninen V , et al. Helsinki Heart Study : primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia  . Safety of treatment , changes in risk factors , and incidence of coronary heart disease . N Engl J Med 1987;317:1237–1245
Evidence on harms was limited , but direct harms seemed minimal ( for resting ECG ) or small ( for exercise ECG ) .
BACKGROUND Coronary heart disease is the leading cause of death in adults .
Screening for abnormalities by using resting or exercise electrocardiography ( ECG ) might help identify persons who would benefit from interventions to reduce cardiovascular risk .
PURPOSE To up date the 2004 U.S. Preventive Services Task Force evidence review on screening for  resting or exercise ECG abnormalities in asymptomatic adults .