CONCLUSIONS In otherwise healthy overweight or obese adults , there is some evidence that in the short term GM may help to reduce BW , but not BMI .
OBJECTIVE Glucomannan ( GM ) , a soluble fiber derived from the plant Amorphophallus konjac , is marketed as being helpful in reducing body weight .
However , the data supporting this cl aim are scarce .
The aim of this review was to systematic ally evaluate the effects of GM on body weight ( BW ) and body mass index ( BMI ) in otherwise healthy obese or overweight children and adults .
Could dyslipidemic children benefit from glucomannan intake?
OBJECTIVE Primary dyslipidemias are major risk factors for cardiovascular disease and should be addressed early in life . The aim of this study was to evaluate , in children affected by primary hypercholesterolemia , the efficacy and tolerability of a short-term treatment with a dietary supplement containing glucomannan . METHODS A double-blind , r and omized , placebo-controlled , cross-over trial was conducted in 36 children ( aged 6 - 15 years ) affected by primary hypercholesterolemia . After a 4-week run-in period with dietary counseling , children received glucomannan or placebo twice-daily for 8 weeks , separated by a 4-week washout period . Lipid profile was assessed at baseline and after each treatment period . RESULTS Glucomannan significantly reduced total cholesterol ( TC ) by 5.1 % ( p = 0.008 ) , low-density lipoprotein cholesterol ( LDL-C ) levels by 7.3 % ( p = 0.008 ) and non-high-density lipoprotein cholesterol by 7.2 % ( p = 0.002 ) as compared with placebo . No significant differences were observed in high-density lipoprotein cholesterol , triglyceride , Apolipoprotein B , and Apolipoprotein A-I concentrations . According to sex , glucomannan significantly reduced in females , but not in males , TC ( -6.1 % , p = 0.011 ) and LDL cholesterol ( -9 % , p = 0.015 ) . No major adverse effects were recorded and only few patients experienced transitory intestinal discomfort . CONCLUSION Treatment with glucomannan of children affected by primary dyslipidemia is well-tolerated and effectively lowers total and LDL cholesterol in females and non-high-density lipoprotein cholesterol , but not Apolipoprotein B in both males and females
CONCLUSIONS In otherwise healthy overweight or obese adults , there is some evidence that in the short term GM may help to reduce BW , but not BMI .
OBJECTIVE Glucomannan ( GM ) , a soluble fiber derived from the plant Amorphophallus konjac , is marketed as being helpful in reducing body weight .
However , the data supporting this cl aim are scarce .
The aim of this review was to systematic ally evaluate the effects of GM on body weight ( BW ) and body mass index ( BMI ) in otherwise healthy obese or overweight children and adults .