The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .
[Preventive therapy for nausea and vomiting in patients on opioid therapy for non-malignant pain in rheumatology].
OBJECTIVE To determine if systematic use of metoclopramide associated with opioids ( Morphine sulfate SR ) decreases the incidence of nausea and vomiting ( N&V ) , established adverse effects of opioids . METHOD Open r and omised study with 132 patients treated for non malignant pain ( 71 women , 61 men , mean age 53.4 years ) . One group ( n = 76 ) was treated with morphine alone ; the other ( n = 56 ) with morphine plus metoclopramide . Mean duration of therapy : 6 days ; mean dosage : 60 mg/d RESULTS In the 2 groups , N&V were present in the first 72 hours . The frequency of N&V in the morphine group was 38.1 % ( conform with the literature ) . The systematic use of metoclopramide decreases the frequency of N&V : p < 0.005 . However the use of morphine > 60 mg/d decreases N&V : p = 0.036 . High dosages of morphine can have an antiemetic effect by interaction with the mu receptors in the antiemetic center and not in the trigger zone which has an emetic effect . CONCLUSION The systematic use of metoclopramide with opioid therapy for non malignant pain in rheumatology decreases the risk of nausea and vomiting
The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .