Unlike the conclusions of the revised Cochrane review the export group set up by the Section on Paediatrics , European Academy of Allergology and Clinical Immunology ( SP-EAACI ) do not find that the exclusion of the four trials dem and s a change of the previous recommendations regarding primary dietary prevention of allergic diseases .
Based on analysis of published peer- review ed observational and interventional studies the results still indicate that breastfeeding is highly recommended for all infants irrespective of atopic heredity .
A dietary regimen is effective in the prevention of allergic diseases in high-risk infants , particularly in early infancy regarding food allergy and eczema .
The most effective dietary regimen is exclusively breastfeeding for at least 4 - 6 months or , in absence of breast milk , formulas with documented reduced allergenicity for at least the first 4 months , combined with avoidance of solid food and cow 's milk for the first 4 months
Predictive value of cord blood IgE in the development of atopic disease and role of breast‐feeding in its prevention
The predictive value of cord blood IgE in the development of atopic disease was evaluated in a prospect i ve study of two groups of infants . Total serum IgE level was ≥ 0.7 U/ml in 44.3 % of the infants with positive family history of atopy and in 16.0 % among those with negative family history . The level of cord blood IgE correlated significantly with the subsequent development of atopic disease in both groups . Cord blood IgE higher than 0.7 U/ml was associated with a high risk of development of atopic eczema and wheezing , 52.8 % and 58.8 % respectively in the groups with or without family history of atopy ; compared with 13.4 % and 1.1 % in the groups with IgE levels less than 0.7 U/ml . Among newborns fed exclusively on breast milk for a minimum of 3 months , the incidence of eczema and wheezing was significantly lower ( 12 % ) compared with findings in the formula‐fed group ( 32 % )
Unlike the conclusions of the revised Cochrane review the export group set up by the Section on Paediatrics , European Academy of Allergology and Clinical Immunology ( SP-EAACI ) do not find that the exclusion of the four trials dem and s a change of the previous recommendations regarding primary dietary prevention of allergic diseases .
Based on analysis of published peer- review ed observational and interventional studies the results still indicate that breastfeeding is highly recommended for all infants irrespective of atopic heredity .
A dietary regimen is effective in the prevention of allergic diseases in high-risk infants , particularly in early infancy regarding food allergy and eczema .
The most effective dietary regimen is exclusively breastfeeding for at least 4 - 6 months or , in absence of breast milk , formulas with documented reduced allergenicity for at least the first 4 months , combined with avoidance of solid food and cow 's milk for the first 4 months