REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .
Management of pregnancy-induced hypertension with pindolol--comparative study with methyldopa.
Thirty-two consecutive women with pregnancy-induced hypertension of early onset were r and omly allocated to treatment with pindolol or methyldopa . There was no difference between the groups in regard to the average time of delivery ( 36.33 vs. 36.6 weeks ) and weight of the newborn ( 2850 vs. 2870 g ) . A significant drop in systolic ( P less than 0.005 ) and diastolic ( P less than 0.05 ) blood pressure was observed in the group of patients treated with pindolol as compared with the methyldopa group . In the pindolol group an improvement in renal function was observed as determined by CCT and serum creatinine . There were no side effects from the drugs in the mother or in the newborn
REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .