Robust statistically significant effects were found for improved diet , aerobic exercise , alcohol and sodium restriction , and fish oil supplements : mean reductions in systolic blood pressure of 5.0 mmHg [ 95 % confidence interval ( CI ) : 3.1 - 7.0 ] , 4.6 mmHg ( 95 % CI : 2.0 - 7.1 ) , 3.8 mmHg ( 95 % CI : 1.4 - 6.1 ) , 3.6 mmHg ( 95 % CI : 2.5 - 4.6 ) and 2.3 mmHg ( 95 % CI : 0.2 - 4.3 ) , respectively , with corresponding reductions in diastolic blood pressure .
Relaxation significantly reduced blood pressure only when compared with non-intervention controls .
We found no robust evidence of any important effect on blood pressure of potassium , magnesium or calcium supplements .
Available evidence does not support relaxation therapies , calcium , magnesium or potassium supplements to reduce blood pressure
PURPOSE To quantify effectiveness of lifestyle interventions for hypertension .
Long-term magnesium supplementation in essential hypertension.
The main objective of this clinical trial was to evaluate the effects of magnesium pidolate ( 15 mmol/day ) on blood pressure at rest and during sympathetic stimulation induced by cold , isometric and tilt test ; peripheral blood flow has been evaluated by strain-gauge plethysmography . Fourteen mild to moderate hypertensives ( 8 males , 6 females , age range 40 - 60 years ) were r and omly given magnesium or placebo in a double-blind parallel clinical trial for 6 months . In the actively treated group magnesium urinary excretion increased from 5.3 + /- 2 to 7.7 + /- 2 mmol/24 h , and serum magnesium changed from 0.9 + /- 0.1 to 1.0 + /- 0.2 mmol/l . On magnesium , BP changed at rest from 156/97 + /- 12/4 to 149/90 + /- 8/3 mm Hg , during cold pressor test from 169/105 + /- 9/6 to 174/105 + /- 15/4 , during isometric exercise from 170/107 + /- 13/9 to 170/105 + /- 20/6 , and during tilt test from 149/96 + /- 11/6 to 153/96 + /- 17/7 mm Hg . Similar changes were observed in the placebo group . Peripheral resistances were 14.7 + /- 4 and 9.8 + /- 2 PRU before and after magnesium , respectively . These data indicate that long-term magnesium pidolate supplementation does not affect blood pressure at rest and during sympathetic stimulation , despite a slight , nonsignificant reduction in forearm peripheral resistance
Robust statistically significant effects were found for improved diet , aerobic exercise , alcohol and sodium restriction , and fish oil supplements : mean reductions in systolic blood pressure of 5.0 mmHg [ 95 % confidence interval ( CI ) : 3.1 - 7.0 ] , 4.6 mmHg ( 95 % CI : 2.0 - 7.1 ) , 3.8 mmHg ( 95 % CI : 1.4 - 6.1 ) , 3.6 mmHg ( 95 % CI : 2.5 - 4.6 ) and 2.3 mmHg ( 95 % CI : 0.2 - 4.3 ) , respectively , with corresponding reductions in diastolic blood pressure .
Relaxation significantly reduced blood pressure only when compared with non-intervention controls .
We found no robust evidence of any important effect on blood pressure of potassium , magnesium or calcium supplements .
Available evidence does not support relaxation therapies , calcium , magnesium or potassium supplements to reduce blood pressure
PURPOSE To quantify effectiveness of lifestyle interventions for hypertension .