No firm evidence was reached according to trial sequential analysis .
Conclusion There is insufficient data to recommend or refute the use of a specific material .
Efficacy of EMD versus calcium hydroxide in direct pulp capping of primary molars: a randomized controlled clinical trial.
OBJECTIVE The aim was to compare the clinical and radiographic efficacy of enamel matrix derivative and self-hardening calcium hydroxide as direct pulp capping material s on decayed primary molars , with observation periods of 1 , 6 , and 12 months . STUDY DESIGN A clinical , r and omized , controlled trial was performed , following the " split-mouth " design . A total of 90 primary molars were treated . Assignation of material s and operative initial side were selected in a r and omized manner . Five outcome variables were considered : internal dentin resorption , pain , gingival sinus tract , root external resorption , and pathologic mobility . The appearance of any of these signs or symptoms was considered to be a failure of treatment . RESULTS Significant statistical or clinical differences were not found between the study groups . Two treatments were judged as failures , 1 per study group ; both occurred during the first postoperative month . CONCLUSIONS The technique used for direct pulp capping on primary molars in this study is recommended on the basis of the obtained clinical and radiographic results
No firm evidence was reached according to trial sequential analysis .
Conclusion There is insufficient data to recommend or refute the use of a specific material .