Although pain was a common criterion for nonresponse and appendectomy , analgesic regimens were poorly described .
BACKGROUND Meta-analyses and a recent guideline acknowledge that conservative management of uncomplicated appendicitis with antibiotics can be successful for patients who wish to avoid surgery .
However , guidance as to specific management does not exist .
Effect of preoperative rectal indomethacin on postoperative pain reduction after open appendectomy.
BACKGROUND One of the major challenges faced by the treatment planning teams is how to manage postoperative pain . Previous studies agreed upon the effects of preoperative administration of nonsteroidal anti-inflammatory drugs on postoperative pain , but all have focused on patients with surgical noninflammatory diseases ( ie , inguinal hernia or breast biopsy ) . The aim of this study was to evaluate the effects of rectal indomethacin on reducing postoperative pain in patients with acute appendicitis . METHODS It is a simple r and omized , clinical trial including 200 patients with acute appendicitis who were divided into two groups ( A1 and A2 ) . The case group ( A1 ) received 100 mg rectal indomethacin during 2 hours before the operation . Pain intensity was assessed in all patients using a visual analog scale ( VAS ) . Similarly , total dosage of meperidine analgesic medication and postoperative time to use of rescue analgesia were evaluated . RESULTS Patients who received preoperative rectal indomethacin ( A1 ) showed a significant reduction in the VAS score . Also , a reduction in total dose of meperidine and longer time to use of rescue analgesic medication were observed in A1 group . CONCLUSION Preoperative administration of rectal indomethacin in acute appendicitis reduces postoperative pain
Although pain was a common criterion for nonresponse and appendectomy , analgesic regimens were poorly described .
BACKGROUND Meta-analyses and a recent guideline acknowledge that conservative management of uncomplicated appendicitis with antibiotics can be successful for patients who wish to avoid surgery .
However , guidance as to specific management does not exist .