The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .
Intrathecal Dexmedetomidine Alleviates Shivering during Cesarean Delivery under Spinal Anesthesia.
Shivering associated with spinal anesthesia during Cesarean delivery is an uncomfortable experience for the parturient , which may also cause adverse effects . In this prospect i ve , r and omized , double-blind , placebo-controlled study , we sought to evaluate the effect of intrathecal dexmedetomidine , administered as an adjunct to hyperbaric bupivacaine for Cesarean delivery , on the incidence and severity of shivering associated with spinal anesthesia . Patients undergoing Cesarean delivery were r and omly allocated to three groups of 30 patients each . Experimental treatments were added to hyperbaric bupivacaine as follows : Patients in group I ( control ) were administered isotonic saline . Patients in groups II and III received dexmedetomidine ( 2.5 , 5 µg , respectively ) , mixed with isotonic saline . Shivering was observed in 11 , 10 and 2 patients in groups I , II and III , respectively . The incidence of shivering in group III was significantly lower than that in groups I ( p=0.005 ) and II ( p=0.01 ) . The severity of shivering was significantly different between the three groups ( p=0.01 ) . There were no significant inter-group differences with respect to mean arterial pressure and heart rate at any time point after administration of intrathecal local anesthesia ( p>0.05 ) . Intrathecal dexmedetomidine ( 5 µg ) administered as an adjunct to hyperbaric bupivacaine during Cesarean delivery significantly reduced the incidence and intensity of shivering associated with spinal anesthesia
The results showed that , compared with placebo , pethidine , fentanyl , dexmedetomidine , and sufentanil significantly reduced the incidence of perioperative shivering .
In addition , compared with sufentanil , fentanyl showed no impact on haemodynamic stability and the incidence of pruritus .
CONCLUSION Pethidine , fentanyl , dexmedetomidine , and sufentanil appear to be effective for preventing perioperative shivering in puerperae undergoing cesarean sections .
Considering the risk-benefit profiles of the included neuraxial adjuvants , fentanyl is probably the optimal choice
BACKGROUND Perioperative shivering is clinical ly common during cesarean sections under neuraxial anesthesia , and several neuraxial adjuvants are reported to have preventive effects on it .
However , the results of current studies are controversial and the effects of these neuraxial adjuvants remain unclear .
AIM To evaluate the effects of neuraxial adjuvants on perioperative shivering during cesarean sections , thus providing an optimal choice for clinical application .