In general , active non-invasive anaesthetic methods seemed to provide favourable results compared to placebo or no anaesthesia , and topical anaesthetic drugs and PSF seemed to result in a better pain reduction than skin cooling .
However , the current evidence is insufficient to provide recommendations for daily clinical practice .
Future studies should also evaluate sex differences in pain perception , have uniformity with regard to vali date d pain measurement scales and address clinical ly significant differences in pain reduction besides statistically significant differences
Pain is a common side-effect of dermatological laser procedures .
Non-invasive anaesthetic drugs and anaesthetic procedures can be used to provide pain relief and increase patient satisfaction and treatment efficacy .
However , it remains unclear which method provides the best pain relief .
The objective of this systematic review was therefore to assess the efficacy and safety of non-invasive anaesthetic methods during dermatological laser procedures .
The Effect of Cold Air Cooling on 585 nm Pulsed Dye Laser Treatment of Port‐Wine Stains
BACKGROUND The use of cryogen spray cooling in the course of dye laser treatment of port-wine stains has established itself in recent years because of its good analgesic and epidermally protective effects . The disadvantages of this kind of evaporative cooling are the cost and , in the case of dichlorodifluoromethane , the effects on the ozone layer . Cold air is an innovative cooling method that costs nearly nothing to use , is environmentally friendly , and can be easily adapted to existing laser systems . OBJECTIVE To examine and evaluate cold air cooling as an alternative method of cooling in laser treatment . METHODS In a prospect i ve study , 13 patients ( 9 female , 4 male ) with port-wine stains were treated with a pulsed dye laser ( λ = 585 nm , τp = 450 μsec ) . In every case , either the entire area or a sample area of the port-wine stain was treated with cold air cooling on 50 % of the surface and without on the other 50 % . Clearance , analgesia , and adverse and concomitant effects were assessed . RESULTS In nine patients ( 69 % ) there were similar results in terms of clearance . In four cases , better lightening results ( in two patients ) and worse lightening results ( in two other patients ) were achieved in the area treated with cold air . Nine of the patients ( 69 % ) felt that the laser impulses accompanied by cold air were significantly less painful . Adverse effects ( purpura , erythema , edema ) and concomitant effects ( hypopigmentation , hyperpigmentation , scars ) were much less marked in the cooled areas . CONCLUSION Cold air is a safe and effective alternative to cryogen spray cooling . It is easy to use , economical , and environmentally friendly . Continuing studies are necessary to determine if there are interactions which affect the tissue
In general , active non-invasive anaesthetic methods seemed to provide favourable results compared to placebo or no anaesthesia , and topical anaesthetic drugs and PSF seemed to result in a better pain reduction than skin cooling .
However , the current evidence is insufficient to provide recommendations for daily clinical practice .
Future studies should also evaluate sex differences in pain perception , have uniformity with regard to vali date d pain measurement scales and address clinical ly significant differences in pain reduction besides statistically significant differences
Pain is a common side-effect of dermatological laser procedures .
Non-invasive anaesthetic drugs and anaesthetic procedures can be used to provide pain relief and increase patient satisfaction and treatment efficacy .
However , it remains unclear which method provides the best pain relief .
The objective of this systematic review was therefore to assess the efficacy and safety of non-invasive anaesthetic methods during dermatological laser procedures .