TSA indicated lack of firm evidence for the results of the meta‐analytic outcomes on clinical and radiographic success .
Conclusion BD and MTA have similar clinical and radiographic success rates based on limited and low‐ quality evidence .
Objectives Pulpotomy is the favored treatment for pulp exposure in carious primary teeth .
This review aim ed to compare the success rates of biodentine ( BD ) and mineral trioxide aggregate ( MTA ) pulpotomies  in primary molars using meta‐ analysis ( MA ) and trial sequential analysis ( TSA ) and also to assess the quality of the results by Grading of Recommendations , Assessment , Development and Evaluation ( GRADE ) .
Short-term treatment outcome of pulpotomies in primary molars using mineral trioxide aggregate and Biodentine: a randomized clinical trial
Introduction An ideal pulpotomy agent for primary molars has been sought for many years . Recently , new material s that allow regeneration of residual pulp tissue have been developed . In this study , we compared the preliminary clinical results obtained using Biodentine and mineral trioxide aggregate ( MTA ) as pulp-dressing agents in pulpotomies of primary molars . Methods A r and omized clinical study was performed in children aged 4–9 years with at least one primary tooth with decay or caries requiring pulp treatment . A total of 90 primary molars requiring pulpotomy were r and omly allocated to the MTA or Biodentine group , and 84 pulpotomies were performed . Clinical and radiographic evaluations were undertaken 6 and 12 months after treatment . All teeth were restored with a reinforced zinc oxide – eugenol base and stainless steel crowns . Statistical analysis using Fisher ’s exact test was performed to determine the significant differences between the groups . Results A total of four clinical failures were observed ; all involved gingival inflammation . The clinical success rate in the MTA Group after 12 months was 92 % ( 36/39 ) , whereas the Biodentine Group obtained 97 % ( 38/39 ) ( p = 0.346 ) . All radiographic failures were observed at the 12-month follow-up evaluation . One molar from MTA Group showed internal resorption obtaining a radiographic success rate of 97 % ( 38/39 ) . Two molars from the Biodentine Group showed radiographic failure ( 1 internal resorption and 1 periradicular radiolucency ) obtaining a radiographic success rate of 95 % ( 37/39 ) . Conclusions Biodentine showed similar clinical results as MTA with comparable success rates when used for pulpotomies of primary molars . However , longer follow-up studies are required to confirm our findings . Clinical relevance This article demonstrates the effectiveness of Biodentine as a primary teeth pulpotomy material , performing similar results as MTA at 12-months evaluation
TSA indicated lack of firm evidence for the results of the meta‐analytic outcomes on clinical and radiographic success .
Conclusion BD and MTA have similar clinical and radiographic success rates based on limited and low‐ quality evidence .
Objectives Pulpotomy is the favored treatment for pulp exposure in carious primary teeth .
This review aim ed to compare the success rates of biodentine ( BD ) and mineral trioxide aggregate ( MTA ) pulpotomies  in primary molars using meta‐ analysis ( MA ) and trial sequential analysis ( TSA ) and also to assess the quality of the results by Grading of Recommendations , Assessment , Development and Evaluation ( GRADE ) .