This review will provide an exhaustive view of medication management models that could be effective for polymedicated , home-dwelling older adults and will allow us to analyze their impact on managing and preventing MRPs .
BACKGROUND Older adults with multiple chronic diseases commonly require complex medication regimes .
When combined with frailty , cognitive impairment , and changing pharmacological prescriptions , older adults ' polymedication regimes increase the risk of medication-related problems ( MRPs ) and hospitalization .
Effective , well-organized medication management could avoid MRPs and their clinical outcomes .
OBJECTIVE Identify medication management models and analyze their impact on managing and preventing MRPs for polymedicated , home-dwelling older adults .
Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial
Introduction Drug-related problems ( DRPs ) are common in the elderly , leading to suboptimal therapy , hospitalisations and increased mortality . The integrated medicines management ( IMM ) model is a multifactorial interdisciplinary methodology aim ing to optimise individual medication therapy throughout the hospital stay . IMM has been shown to reduce readmissions and drug-related hospital readmissions . Using the IMM model as a template , we have design ed an intervention aim ing both to improve medication safety in hospitals , and communication across the secondary and primary care interface . This paper presents the study protocol to explore the effects of the intervention with regard to healthcare use , health-related quality of life ( HRQoL ) and medication appropriateness in elderly patients . Methods and analysis A total of 500 patients aged ≥70 years will be included and r and omised to control ( st and ard care ) or intervention group ( 1:1 ) . The intervention comprises five steps mainly performed by pharmacists : ( 1 ) medication reconciliation at admission , ( 2 ) medication review during hospital stay , ( 3 ) patient counselling about the use of medicines , ( 4 ) a comprehensible and patient-friendly medication list with explanations in discharge summary and ( 5 ) postdischarge phone calls to the primary care level . The primary outcome is the difference between intervention and control patients in the rate of emergency medical visits ( acute readmissions and visits to emergency department ) 12 months after discharge . Secondary outcomes include length of index hospital stay , time to first readmission , mortality , hip fractures , strokes , medication changes , HRQoL and medication appropriateness . Patient inclusion started in September 2016 . Ethics and dissemination The trial was approved by the Norwegian Centre for Research Data and the Norwegian Data Protection Authority . We aim to publish the results in international peer- review ed open access journals , at national and international conferences , and as part of two PhD theses . Trial registration number NCT02816086
This review will provide an exhaustive view of medication management models that could be effective for polymedicated , home-dwelling older adults and will allow us to analyze their impact on managing and preventing MRPs .
BACKGROUND Older adults with multiple chronic diseases commonly require complex medication regimes .
When combined with frailty , cognitive impairment , and changing pharmacological prescriptions , older adults ' polymedication regimes increase the risk of medication-related problems ( MRPs ) and hospitalization .
Effective , well-organized medication management could avoid MRPs and their clinical outcomes .
OBJECTIVE Identify medication management models and analyze their impact on managing and preventing MRPs for polymedicated , home-dwelling older adults .