Clinician- and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment .
However , the results of self-reported outcome measures failed to reach significance .
The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment .
Anxiety is a common problem in children and adolescents with autism spectrum disorder ( ASD ) .
This meta- analysis aim ed to systematic ally evaluate the evidence for the use of psychosocial interventions to manage anxiety in this population .
Cognitive behavioural therapy ( CBT ) was the primary intervention modality studied .
The effect of cognitive-behavioral therapy versus treatment as usual for anxiety in children with autism spectrum disorders: a randomized, controlled trial.
OBJECTIVE To examine the efficacy of a modular cognitive-behavioral therapy ( CBT ) protocol relative to treatment as usual ( TAU ) among children with high-functioning autism spectrum disorders ( ASD ) and clinical ly significant anxiety .  METHOD A total of 45 children ( 7 - 11 years of age ) with high-functioning ASD and clinical ly significant anxiety were r and omized to receive 16 sessions of weekly CBT or TAU for an equivalent duration . After screening , assessment s were conducted at baseline , post-treatment , and 3-month follow-up . Raters were blind to treatment condition . RESULTS Youth receiving CBT showed substantial improvement relative to TAU on primary anxiety outcomes . Of 24 children r and omized to the CBT arm , 18 ( 75 % ) were treatment responders , versus only 3 of 21 children ( 14 % ) in the TAU arm . Gains were generally maintained at 3-month follow-up for CBT responders . CONCLUSIONS Relative to usual care , CBT adapted for anxious youth with high-functioning ASD demonstrates large effects in reducing anxiety symptoms . This study contributes to the growing literature supporting adapted CBT approaches for treating anxiety in youth with ASD
Clinician- and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment .
However , the results of self-reported outcome measures failed to reach significance .
The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment .
Anxiety is a common problem in children and adolescents with autism spectrum disorder ( ASD ) .
This meta- analysis aim ed to systematic ally evaluate the evidence for the use of psychosocial interventions to manage anxiety in this population .
Cognitive behavioural therapy ( CBT ) was the primary intervention modality studied .