The evidence for the effectiveness of B serrata extracts is encouraging but not compelling
OBJECTIVE To assess evidence from r and omised clinical trials about the effectiveness of  extracts of Boswellia serrata ( frankincense ) .
The Norwegian Colorectal Cancer Prevention (NORCCAP) screening study: baseline findings and implementations for clinical work-up in age groups 50-64 years.
BACKGROUND R and omized controlled trials of sufficient power testing the long-term effect of screening for colorectal neoplasia only exist for faecal occult blood testing ( FOBT ) . There is indirect evidence that flexible sigmoidoscopy ( FS ) may have a greater yield . The aim of this study was to determine the diagnostic yield of screening with FS or a combination of FS and FOBT in an average-risk population in an urban and combined urban and rural population in Norway . METHODS 20,780 men and women ( 1:1 ) , aged 50 - 64 years , were invited for once-only screening ( FS only or a combination of FS and FOBT ( 1:1 ) )  by r and omization from the population registry . A positive FS was defined as a finding of any neoplasia or any polyp > or = 10 mm . A positive FS or FOBT qualified for colonoscopy . RESULTS Overall attendance was 65 % . Forty-one ( 0.3 % ) cases of CRC were detected . Any adenoma was found in 2208 ( 17 % ) participants and 545 ( 4.2 % ) had high-risk adenomas . There was no difference in diagnostic yield between the FS and the FS and FOBT group regarding CRC or high-risk adenoma . Work-up load comprised 2821 colonoscopies in 2524 ( 20 % ) screenees and 10 % of screenees were recommended later colonoscopy surveillance . There were no severe complications at FS , but six perforations after therapeutic colonoscopy ( 1:336 ) . CONCLUSIONS The present study bodes well for future management of a national screening programme , provided that follow-up results reflect adequate proof of a net benefit . It is highly question able whether the addition of once-only FOBT to FS will contribute to this effect
The evidence for the effectiveness of B serrata extracts is encouraging but not compelling
OBJECTIVE To assess evidence from r and omised clinical trials about the effectiveness of  extracts of Boswellia serrata ( frankincense ) .