This study provides robust evidence supporting the cost-effectiveness of smoking cessation programs for hospitalized patients .
In addition , the results indicated that the degree of cost-effectiveness of the inpatient smoking cessation program might not be related to either the components of the program or method ological variations in the cost-effectiveness analysis .
This systematic review examined the characteristics of published cost-effectiveness analyses of  inpatient smoking cessation programs  and assessed the method ological quality of the selected studies , to provide policymakers with economic evidence for this type of program .
Cost-effectiveness of smoking cessation treatment initiated during psychiatric hospitalization: analysis from a randomized, controlled trial.
OBJECTIVE We examined the cost-effectiveness of smoking cessation treatment for psychiatric in patients . METHOD Smokers , regardless of intention to quit , were recruited during psychiatric hospitalization and r and omized to receive stage-based smoking cessation services or usual aftercare .  Smoking cessation services , quality of life , and biochemically verified abstinence from cigarettes were assessed during 18 months of follow-up . A Markov model of cost-effectiveness over a lifetime horizon was constructed using trial findings and parameters obtained in a review of the literature on quit and relapse rates and the effect of smoking on health care cost , quality of life , and mortality . RESULTS Among 223 smokers r and omized between 2006 and 2008 , the mean cost of smoking cessation services was $ 189 in the experimental treatment group and $ 37 in the usual care condition ( P < .001 ) . At the end of follow-up , 18.75 % of the experimental group was abstinent from cigarettes , compared to 6.80 % abstinence in the usual care group ( P < .05 ) . The model projected that the intervention added $ 43 in lifetime cost and generated 0.101 additional quality -adjusted life-years ( QALYs ) , an incremental cost-effectiveness ratio of $ 428 per QALY . Probabilistic sensitivity analysis found the experimental intervention was cost-effective against the acceptance criteria of $ 50,000/QALY in 99.0 % of the replicates . CONCLUSIONS A cessation intervention for smokers identified in psychiatric hospitalization did not result in higher mental health care costs in the short-run and was highly cost-effective over the long-term . The stage-based intervention was a feasible and cost-effective way of addressing the high smoking prevalence in persons with serious mental illness . TRIAL REGISTRATION Clinical Trials.gov identifier : NCT00136812
This study provides robust evidence supporting the cost-effectiveness of smoking cessation programs for hospitalized patients .
In addition , the results indicated that the degree of cost-effectiveness of the inpatient smoking cessation program might not be related to either the components of the program or method ological variations in the cost-effectiveness analysis .
This systematic review examined the characteristics of published cost-effectiveness analyses of  inpatient smoking cessation programs  and assessed the method ological quality of the selected studies , to provide policymakers with economic evidence for this type of program .