There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
A novel infant formula milk with added long-chain polyunsaturated fatty acids from single-cell sources: a study of growth, satisfaction and health
Objective : To evaluate the growth , feeding and health of babies fed a novel infant formula milk  with added long chain polyunsaturated fatty acids ( LCPs ) produced from single-cell sources , at concentrations similar to those found in mature breast milk . Design : R and omized double-blind control trial . Subjects : One-hundred and forty healthy , full-term infants of birth weight 2.5–4.5 kg born at the Maternity Department , East Glamorgan General Hospital , Wales , whose mothers had already decided to bottle feed . Interventions : Subjects were r and omized to two groups ; one ( control group ) to receive a st and ard formula milk and the other to receive the trial milk with added LCPs . Milks were supplied in a double-blind fashion and given for the first 12 weeks of life . Anthropometric measurements were made at recruitment , 3 months , 6 months and 1 y. Feeding diaries were completed at 6 weeks and 3 months , and a parental record was kept of any ill health suffered by the subjects during the first year of life . Results : Of 140 infants recruited , 31 did not complete the protocol . Small but statistically significant differences were found only in the subscapular skinfold thickness at 6 weeks and 3 months , that in the trial group being slightly higher , but unlikely to be of any clinical importance . No differences were found in the feeding patterns of the infants in the two groups . Stool patterns were similar , as were the frequencies of illness and allergy . Conclusions : This study supports the view that LCPs from single-cell sources do not have detrimental effects on the growth , feeding and general health of infants . Sponsorship : The research nurse and equipment used in this study were funded by Cow & Gate Nutricia ( UK ) Ltd . European Journal of Clinical Nutrition ( 2000 ) 54 ,
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .