In contrast , fasting plasma glucose , fasting plasma insulin as well as the homeostasis model assessment of insulin resistance were not affected by the amounts of MUFA in the dietary protocol s. Conclusions : In summary , this systematic review found that high MUFA diets appear to be effective in reducing HbA1c , and therefore , should be recommended in the dietary regimes of T2D
Background / Aims : In 2008 , the American Diabetes Association recommended low-carbohydrate or low-fat diets for weight management in patients with established type 2 diabetes ( T2D ) , while the amount of monounsaturated fatty acids ( MUFA ) was not specified .
This systematic review focused on the effects of diets high in MUFA versus diets low in MUFA on important risk factors of T2D ( i.e. plasma glucose , insulin , homeostasis model assessment of insulin resistance and glycosylated haemoglobin , HbA1c ) .
Effects of meals rich in either monounsaturated or saturated fat on lipid concentrations and on insulin secretion and action in subjects with high fasting triglyceride concentrations.
BACKGROUND The nature of dietary fats and fasting concentrations of triglycerides affect postpr and ial hypertriglyceridemia and glucose homeostasis . OBJECTIVES The objectives were to examine the effects of meals enriched in monounsaturated fatty acids ( MUFAs ) or saturated fatty acids ( SFAs ) on postpr and ial lipid , glucose , and insulin concentrations and to examine the extent of β cell function and insulin sensitivity in subjects with high fasting triglyceride concentrations . DESIGN Fourteen men with fasting hypertriglyceridemia and normal glucose tolerance were given meals ( ≈10 kcal/kg body weight ) containing MUFAs , SFAs , or no fat . Blood sample s were collected at baseline and hourly over 8 h for analysis . RESULTS The high-fat meals significantly increased postpr and ial concentrations of triglycerides , nonesterified fatty acids , and insulin and postpr and ial indexes of β cell function . However , postpr and ial indexes of insulin sensitivity decreased significantly . These effects were significantly attenuated with MUFAs relative to SFAs . CONCLUSIONS MUFAs postpr and ially buffered β cell hyperactivity and insulin intolerance relative to SFAs in subjects with high fasting triglyceride concentrations . These data suggest that , in contrast with SFAs , MUFA-based strategies may provide cardiovascular benefits to persons at risk by limiting lipid and insulin excursions and may contribute to optimal glycemic control after meal challenges
In contrast , fasting plasma glucose , fasting plasma insulin as well as the homeostasis model assessment of insulin resistance were not affected by the amounts of MUFA in the dietary protocol s. Conclusions : In summary , this systematic review found that high MUFA diets appear to be effective in reducing HbA1c , and therefore , should be recommended in the dietary regimes of T2D
Background / Aims : In 2008 , the American Diabetes Association recommended low-carbohydrate or low-fat diets for weight management in patients with established type 2 diabetes ( T2D ) , while the amount of monounsaturated fatty acids ( MUFA ) was not specified .
This systematic review focused on the effects of diets high in MUFA versus diets low in MUFA on important risk factors of T2D ( i.e. plasma glucose , insulin , homeostasis model assessment of insulin resistance and glycosylated haemoglobin , HbA1c ) .