Overall , the current literature supports clearly the dose-response relationship between physical activity and the seven chronic conditions identified .
Moreover , higher levels of physical activity reduce the risk for premature all-cause mortality .
The current Canadian guidelines appear to be appropriate to reduce the risk for the seven chronic conditions identified above and all-cause mortality
This systematic review examines critically the scientific basis for Canada 's Physical Activity Guide for Healthy Active Living for adults .
Particular reference is given to the dose-response relationship between physical activity and premature all-cause mortality and seven chronic diseases ( cardiovascular disease , stroke , hypertension , colon cancer , breast cancer , type 2 diabetes ( diabetes mellitus ) and osteoporosis ) .
The strength of the relationship between physical activity and specific health outcomes is evaluated critically .
Recreational physical activity and risk of postmenopausal breast cancer in a large cohort of US women
Due to its potential effects on ovarian hormone production , physical activity has been proposed as a modifiable risk factor for breast cancer . The authors analyzed data from the American Cancer Society Cancer Prevention Study II ( CPS-II ) Nutrition Cohort to examine the association between various measures of physical activity and postmenopausal breast cancer risk . Information on physical activity was obtained in 1992 via a self-administered question naire for 72,608 postmenopausal female participants who were cancer-free . During the five year prospect i ve follow-up , 1520 incident breast cancer cases were identified among these women . Cox proportional hazards modeling was used to compute hazard rate ratios ( RR ) and to adjust for potential confounding factors including mammography . Women who were most physically active ( > 42.0 MET-h/week ) at baseline had 29 % lower incidence rates than active women with the least activity ( > 0–7.0 MET-h/week ) ( 95 % CI , 0.49–1.02 ) . The difference in risk was largest for localized breast cancer , and for women who did not use hormone replacement therapy ( HRT ) at enrollment . Our findings are consistent with other studies that show lower risk of postmenopausal breast cancer associated with regular physical activity
Overall , the current literature supports clearly the dose-response relationship between physical activity and the seven chronic conditions identified .
Moreover , higher levels of physical activity reduce the risk for premature all-cause mortality .
The current Canadian guidelines appear to be appropriate to reduce the risk for the seven chronic conditions identified above and all-cause mortality
This systematic review examines critically the scientific basis for Canada 's Physical Activity Guide for Healthy Active Living for adults .
Particular reference is given to the dose-response relationship between physical activity and premature all-cause mortality and seven chronic diseases ( cardiovascular disease , stroke , hypertension , colon cancer , breast cancer , type 2 diabetes ( diabetes mellitus ) and osteoporosis ) .
The strength of the relationship between physical activity and specific health outcomes is evaluated critically .