Conclusion This study suggests that the probiotics supplementation could potentially reduce the weight gain and improve some of the associated metabolic parameters , which may become an effective strategy for the prevention and treatment of obesity in adult individuals
Background The prevalence of overweight/obesity in adults is raised to 39 % , which is nearly tripled more than 1975 .
The alteration of the gut microbiome has been widely accepted as one of the main causal factors .
To find an effective strategy for the prevention and treatment of overweight/obesity , a systematic review and meta- analysis were design ed .
Comparison of the effect of daily consumption of probiotic compared with low-fat conventional yogurt on weight loss in healthy obese women following an energy-restricted diet: a randomized controlled trial.
BACKGROUND Despite evidence for the beneficial effects of probiotics and low-fat dairy products , to our knowledge , no study has compared the beneficial effect on weight loss of consuming a probiotic yogurt ( PY ) compared with a st and ard low-fat yogurt ( LF ) during a hypoenergetic program . OBJECTIVE We compared the effect of the PY with LF yogurt consumption on body weight and cardiometabolic risk factors in women during a weight-loss program . DESIGN Overweight and obese women [ body mass index ( in kg/m(2 ) ) : 27 - 40 ; age : 18 - 50 y ) who usually consumed st and ard LFs  were asked to consume either PY or LF every day with their main meals for 12 wk while following a weight-loss program . RESULTS A total of 89 participants were r and omly assigned to one of the 2 intervention groups . Baseline variables were not significantly different between groups . A statistically significant reduction in anthropometric measurements and significant improvements in cardiometabolic risk characteristics were observed over the 12 wk in both groups . However , no significant differences in weight loss and anthropometric measurements were seen between groups after the intervention . Compared with the LF group , the PY group had a greater ( mean ± SD ) decrease in total cholesterol ( PY = -0.36 ± 0.10 mmol/L , LF = -0.31 ± 0.10 mmol/L ; P = 0.024 ) , low-density lipoprotein cholesterol ( PY = -0.35 ± 0.10 mmol/L , LF = -0.31 ± 0.11 mmol/L ; P = 0.018 ) , homeostasis model assessment of insulin resistance ( PY = -0.55 ± 0.32 , LF = -0.42 ± 0.20 ; P = 0.002 ) , 2-h postpr and ial glucose ( PY = -0.61 ± 0.24 mmol/L , LF = -0.44 ± 0.19 mmol/L ; P < 0.001 ) , and fasting insulin concentration ( PY = -1.76 ± 1.01 mU/mL , LF = -1.32 ± 0.62 mU/mL ; P = 0.002 ) , as secondary endpoints after the study . No significant differences were found for fasting plasma glucose , high-density lipoprotein cholesterol , or triglycerides within both groups after the 12 wk . CONCLUSION Consumption of PY compared with LF with main meals showed no significant effects on weight loss . However , it may have positive effects on lipid profiles and insulin sensitivity during a weight-loss program . This trial was registered at http://www.i rct .ir/ as I RCT 201402177754N8
Conclusion This study suggests that the probiotics supplementation could potentially reduce the weight gain and improve some of the associated metabolic parameters , which may become an effective strategy for the prevention and treatment of obesity in adult individuals
Background The prevalence of overweight/obesity in adults is raised to 39 % , which is nearly tripled more than 1975 .
The alteration of the gut microbiome has been widely accepted as one of the main causal factors .
To find an effective strategy for the prevention and treatment of overweight/obesity , a systematic review and meta- analysis were design ed .