Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Infection after laparoscopic cholecystectomy: are antibiotics really necessary?
OBJECTIVE To establish the incidence of infection after laparoscopic cholecystectomy , and assess the need for antibiotic prophylaxis . DESIGN Prospect i ve open study . SETTING University teaching hospital , United Kingdom . SUBJECTS 253 consecutive patients undergoing laparoscopic cholecystectomy between September 1990 and January 1993 . INTERVENTIONS A single intravenous dose of cefuroxime 1.5 g at induction of general anaesthesia . MAIN OUTCOME MEASURES Infective complications . RESULTS Patients were review ed at two weeks and 12 months . At two weeks there had been two wound infections ( one resolved spontaneously and the other required removal of a gallstone from the subcutaneous tissue ) , two chest infections ( treated with antibiotics orally and physiotherapy ) , and one subhepatic abscess ( drained percutaneously under ultrasonographic control ) . No other complications were reported at 12 months . CONCLUSIONS Routine antibiotic prophylaxis may be unnecessary during elective laparoscopic cholecystectomy , but a r and omised controlled trial is necessary to confirm this
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .