Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .
Effects of a 7-day eccentric training period on muscle damage and inflammation.
PURPOSE This study examined the effects of a 7-d repeated maximal isokinetic eccentric training period on the indicators of muscle damage and inflammatory response . METHODS Twenty-two college-age males were r and omly assigned to  eccentric training ( ET )  ( N = 12 ) and  control groups  ( CON ) ( N = 10 ) . The initial exercise was 30 repetitions of maximal voluntary isokinetic eccentric contraction ( ECC1 ) on nondominant elbow flexors with Cybex 6000 at 60 degrees.s-1 angular velocity . The ET group performed the same exercise for the following 6 consecutive days ( referred to as ECC2 to ECC7 ) after ECC1 .  Upper arm circumference ( CIR ) , range of motion ( ROM ) , and maximal isometric force ( MIF ) were measured before , immediately after , and every 24 h for 7 consecutive days after ECC1 . Plasma creatine kinase ( CK ) , lactate dehydrogenase ( LDH ) , glutamic oxaloacetate transaminase ( GOT ) , leukocyte counts , and serum interleukin-1beta and -6 ( IL-1beta , IL-6 ) levels were assessed before ; at 2 h ; and at 1 , 3 , 4 , 6 , and 7 d after ECC1 . Muscle soreness was measured before and for 7 consecutive days after ECC1 . RESULTS The ECC1 produced significant changes in most of the measures for both groups ( P < 0.05 ) , with the exception of leukocyte counts ( P > 0.05 ) . No indicators of increased damage ( P > 0.05 ) were found from ECC2 to ECC7 for the ET group . CONCLUSION Continuous intensive isokinetic eccentric training performed with damaged muscles did not exacerbate muscle damage and inflammation after ECC1 . In addition , a muscular " adaptation effect " may occur as early as 24 h after ECC1 , as shown by the ET group 's performance for 6 consecutive days after ECC1
Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .