Compared with general anaesthesia , a central neuraxial block may reduce the zero to 30-day mortality for patients undergoing surgery with intermediate to high cardiac risk ( level of evidence , moderate ) .
BACKGROUND Various beneficial effects derived from neuraxial blocks have been reported .
However , it is unclear whether these effects have an influence on perioperative mortality and major pulmonary/cardiovascular complications .
OBJECTIVES Our primary objective was to summarize Cochrane systematic review s that assess the effects of neuraxial blockade on perioperative rates of death , chest infection and myocardial infa rct ion by integrating the evidence from all such review s that have compared neuraxial blockade with or without general anaesthesia versus general anaesthesia alone for different types of surgery in various population s. Our secondary objective was to summarize the evidence on adverse effects ( an adverse event for which a causal relation between the intervention and the event is at least a reasonable possibility ) of neuraxial blockade .
The effect of delivery on umbilical arterial cord blood gases and lipid peroxides: comparison of vaginal delivery and cesarean section.
Umbilical arterial blood gas analysis is the most objective method to assess fetal well being at birth , is the gold st and ard assessment of uteroplacental function and fetal oxygenation/acid-base status at birth , and it excludes the diagnosis of birth asphyxia in approximately 80 % of depressed newborns at term . This study was design ed to determine the effect of the type of delivery on umbilical cord blood gases and on free radical activity together with antioxidation in the fetus . Ninety-six pregnant women between 37 and 42 weeks of gestation were included to the study and r and omly assigned to the one of three groups : Group 1 ( n = 40 ) were vaginally delivered , Group 2 ( n = 26 ) had cesarean section with epidural anaesthesia  , and Group 3 ( n = 30 ) had cesarean section under general anaesthesia .  Umbilical artery blood gas analysis  was performed just after the delivery of the fetus together with melondealdehyde and glutathione . The umbilical arterial PO2 was found to be higher in Group 3 , and malondealdehyde and glutathione levels were lower in newborns of Group 2 . It can be concluded that cesarean section with epidural anaesthesia is safer when lipid peroxides are concerned
Compared with general anaesthesia , a central neuraxial block may reduce the zero to 30-day mortality for patients undergoing surgery with intermediate to high cardiac risk ( level of evidence , moderate ) .
BACKGROUND Various beneficial effects derived from neuraxial blocks have been reported .
However , it is unclear whether these effects have an influence on perioperative mortality and major pulmonary/cardiovascular complications .
OBJECTIVES Our primary objective was to summarize Cochrane systematic review s that assess the effects of neuraxial blockade on perioperative rates of death , chest infection and myocardial infa rct ion by integrating the evidence from all such review s that have compared neuraxial blockade with or without general anaesthesia versus general anaesthesia alone for different types of surgery in various population s. Our secondary objective was to summarize the evidence on adverse effects ( an adverse event for which a causal relation between the intervention and the event is at least a reasonable possibility ) of neuraxial blockade .