Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .
The Effects of Creatine Supplementation on Exercise‐Induced Muscle Damage
This investigation evaluated the effects of oral creatine ( Cr ) supplementation on markers of exercise-induced muscle damage following high-force eccentric exercise in subjects r and omly administered Cr or placebo ( P ) in a double-blind fashion . When injected , exogenous phosphocreatine has been shown to stabilize the muscle membrane in cardiac tissue and enhance recovery of strength and power following injury . Twenty-three men aged 18–36 years ingested either 20 g of Cr or P for 5 days . Criterion measures were maximal isometric force of the elbow flexors ( MIF ) , range of motion ( ROM ) about the elbow , mid and distal arm circumference ( CIR ; to assess swelling ) , soreness with movement and palpation ( SOR ) , and blood levels of creatine kinase ( CK ) and lactate dehydrogenase ( LDH ) . Following the supplementation period , subjects performed 50 maximal eccentric contractions of the elbow flexors . Criterion measures were assessed pre-exercise , immediately postexercise , and for 5 days after exercise . Both groups experienced a significant loss of MIF and ROM ( time effect , p < 0.05 ) . There was a significant increase in CIR of the mid and distal biceps , SOR with movement and palpation , CK , and LDH ( time effect , p < 0.05 ) , indicating that there was significant muscle damage . However , there were no significant differences in any of the criterion measures between groups ( group χ time interaction term , p > 0.05 ) . The pattern of change over the 6 days , in response to the eccentric exercise , was nearly identical between groups . These data suggest that 5 days of Cr supplementation does not reduce indirect markers of muscle damage or enhance recovery from high-force eccentric exercise
Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .