There was no consistency among the protocol s regarding length of antibiotic use , discharge criteria , or use of home antibiotics following discharge .
Limiting duration of antibiotic use to3 days did not appear to be associated with higher rates of intraabdominal abscess or wound infection .
In the absence of higher-level evidence , shortening of antibiotic regimens following surgery for pediatric complicated appendicitis appears to be safe
The suitable duration of antibiotic use following appendectomy for advanced appendicitis in children is still debated .
Ceftazidime/metronidazole versus netilmicin/metronidazole in the treatment of perforated appendicitis in children.
One hundred children with peritonitis result ing from a perforated appendix were treated with ceftazidime or netilmicin . Metronidazole was added to both groups to treat the anaerobic organisms commonly associated with the infecting aerobic organisms in peritonitis . Escherichia coli was the most common aerobe found in peritoneal pus . Wound infection occurred in nine patients of the netilmicin group and in none treated with ceftazidime ( P less than 0.01 ) . No bacterial resistance was evident in the ceftazidime group , but gram-positive streptococci found in eight patients were resistant to netilmicin . Thus it is recommended that an antibiotic of the penicillin group be added if netilmicin is used to treat peritonitis . The results indicate that ceftazidime was more effective than netilmicin in the treatment of children with peritonitis result ing from a perforated appendix
There was no consistency among the protocol s regarding length of antibiotic use , discharge criteria , or use of home antibiotics following discharge .
Limiting duration of antibiotic use to3 days did not appear to be associated with higher rates of intraabdominal abscess or wound infection .
In the absence of higher-level evidence , shortening of antibiotic regimens following surgery for pediatric complicated appendicitis appears to be safe
The suitable duration of antibiotic use following appendectomy for advanced appendicitis in children is still debated .