In conclusion , preoperative exercise-based training improves pulmonary function before surgery and reduces in-hospital length of stay and postoperative complications after lung resection surgery for lung cancer
Lung cancer is the leading cause of cancer-related death worldwide .
For early stages of the disease , lung resection surgery remains the best treatment with curative intent , but significant morbidity is associated , especially among patients with poor pulmonary function and cardiorespiratory fitness .
In those cases , the implementation of a preoperative exercise-based intervention could optimize patient 's functional status before surgery and improve postoperative outcomes and enhance recovery .
The aim of this systematic review is to provide the current body of knowledge regarding the effectiveness of a preoperative exercise-based intervention on postoperative and functional outcomes in patients with lung cancer su bmi tted to lung resection surgery .
The extent of lung parenchyma resection significantly impacts long-term quality of life in patients with non-small cell lung cancer.
BACKGROUND Secondary to clinical outcome , health-related quality of life ( QOL ) after resection of non-small cell lung cancer ( NSCLC ) is of particular interest . However , few studies have explored QOL following lung resection . METHODS Between January 1998 and December 2004 , a total of 159 patients with NSCLC underwent surgical resection and were enrolled in this prospect i ve study . QOL and clinical data were assessed prior to resection and for up to 24 months after surgery by applying the European Organization for Research and Treatment of Cancer core question naire and the lung-specific question naire , the European Organization for Research and Treatment of Cancer lung-specific module . QOL was calculated , and QOL following bilobectomy/lobectomy was compared with QOL after pneumonectomy . RESULTS Overall , the 5-year survival rate was 42 % . Mean survival of the pneumonectomy group was slightly lower than that of the bilobectomy/lobectomy group , although the difference was not statistically significant ( p = 0.058 ) . The rate of complications was not significantly different between the two groups . After a postoperative drop , most QOL indicators remained near baseline for up to 24 months , with the exception of physical function ( p < 0.001 ) , pain ( p = 0.034 ) , and dyspnoea ( p < 0.001 ) , which remained significantly impaired . QOL was significantly better ( difference > 10 points ) after bilobectomy/lobectomy than after pneumonectomy . However , differences were statistically significant only with regards to physical function ( at 3 months ) , social function ( at 3 and 6 months ) , role function ( at 3 , 6 , and 12 months ) , global health ( at 3 and 6 months ) , and pain ( at 6 months ) . CONCLUSIONS Patients who underwent lung resection for NSCLC failed to make a complete recovery after 24 months . Patients who underwent pneumonectomy had significantly worse QOL values and a decreased tendency to recover , compared with patients who underwent bilobectomy/lobectomy . Therefore , major lung resection has a much more serious impact on the QOL of affected patients than does major visceral surgery
In conclusion , preoperative exercise-based training improves pulmonary function before surgery and reduces in-hospital length of stay and postoperative complications after lung resection surgery for lung cancer
Lung cancer is the leading cause of cancer-related death worldwide .
For early stages of the disease , lung resection surgery remains the best treatment with curative intent , but significant morbidity is associated , especially among patients with poor pulmonary function and cardiorespiratory fitness .
In those cases , the implementation of a preoperative exercise-based intervention could optimize patient 's functional status before surgery and improve postoperative outcomes and enhance recovery .
The aim of this systematic review is to provide the current body of knowledge regarding the effectiveness of a preoperative exercise-based intervention on postoperative and functional outcomes in patients with lung cancer su bmi tted to lung resection surgery .