In older people with osteoporosis , higher protein intake ( ≥ 0.8-g/kg body weight/day , i.e. , above the current RDA ) is associated with higher BMD , a slower rate of bone loss , and reduced risk of hip fracture , provided that dietary calcium intakes are adequate .
Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels , together with an increase in IGF-I and a decrease in PTH .
There is no evidence that diet-derived acid load is deleterious for bone health .
Thus , insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly .
A summary of systematic review s and meta-analyses addressing the benefits and risks of dietary protein intakes  for  bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk , provided calcium intakes are adequate .
Several systematic review s and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults .
Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone .
Variation in protein intakes within the “ normal ” range accounts for 2–4 % of BMD variance in adults .
Phosphate and carbonate salts of calcium support robust bone building in osteoporosis.
BACKGROUND Calcium is an essential cotherapy in osteoporosis treatment . The relative effectiveness of various calcium salts for this purpose is uncertain . Many older women with osteoporosis have phosphorus intakes of < 70 % of the Recommended Dietary Allowance . OBJECTIVE Our objective was to test the hypothesis that calcium phosphate would better support anabolic bone building than would calcium carbonate . DESIGN This study was a 12-mo , r and omized , positive-comparator , 2-arm , single-blind clinical trial in 211 patients treated with teriparatide who consumed < 1000 mg phosphorus/d . Participants were r and omly assigned to receive , in addition to teriparatide and 1000 IU cholecalciferol , 1800 mg calcium/d as either tricalcium phosphate or calcium carbonate . The primary endpoints were changes in lumbar spine and total hip bone mineral densities ( BMDs ) ; secondary endpoints were changes in bone resorption biomarkers and serum and urine calcium and phosphorus concentrations . RESULTS In the combined group , the lumbar spine BMD increased by 7.2 % , and total hip BMD increased by 2.1 % ( P < 0.01 for both ) . However , there was no significant difference between calcium-treatment groups , and there were no significant between-group differences in serum calcium and phosphorus concentrations or in urine calcium concentrations . Bone resorption biomarkers increased in both groups , as expected with teriparatide , but the increases in the 2 calcium groups did not differ significantly . CONCLUSIONS Tricalcium phosphate and calcium carbonate appear to be approximately equally effective in supporting bone building with a potent anabolic agent ; phosphate salt may be preferable in patients with restricted phosphorus intakes . This trial was registered at clinical trials.gov as NCT00074711
In older people with osteoporosis , higher protein intake ( ≥ 0.8-g/kg body weight/day , i.e. , above the current RDA ) is associated with higher BMD , a slower rate of bone loss , and reduced risk of hip fracture , provided that dietary calcium intakes are adequate .
Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels , together with an increase in IGF-I and a decrease in PTH .
There is no evidence that diet-derived acid load is deleterious for bone health .
Thus , insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly .
A summary of systematic review s and meta-analyses addressing the benefits and risks of dietary protein intakes  for  bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk , provided calcium intakes are adequate .
Several systematic review s and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults .
Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone .
Variation in protein intakes within the “ normal ” range accounts for 2–4 % of BMD variance in adults .