Contractubex showed best results in the prevention of pathological scars .
BACKGROUND The treatment and prevention of  hypertrophic scars and keloids  represents a special challenge particularly in plastic surgery .
Given their simple , non-invasive and painless application , topical preparations are an attractive therapeutic option .
On the part of the patients , the efficacy in prevention of and therapy for hypertrophic scars and keloids of these topical preparations is regularly question ed .
The clarification of this issue is subject of this review .
The Efficacy of Topical Silicone Gel Elastomers in the Treatment of Hypertrophic Scars, Keloid Scars, and Post–Laser Exfoliation Erythema
Background Dermatix is a Food and Drug Administration ( FDA ) -registered substantial equivalent to silicone gel sheeting for the prevention and management of hypertrophic scars and keloids . Methods A 90-day prospect i ve study evaluated the efficacy of Dermatix , silicone gel sheeting , and a combination of these treatments in improving scars for 30 patients . Each patient had a bilateral scar that served as an untreated control . The outcome measures included profilometry analysis of scar topography before and after punch biopsies of the control and treated scars , symptoms associated with the scars , and patient evaluations of the ease of treatment . Results The results showed better resolution and improvement of scars with Dermatix treatment or the combined use of Dermatix and silicone gel sheeting than with silicone gel sheeting alone .  Wound erythema was reduced , and collagen architectural reorientation was demonstrated histologically . Patients rated Dermatix as easier to use than silicone gel sheeting . Both Dermatix and silicone gel sheeting reduced symptoms of itching , irritation , and skin maceration . Conclusion The results of this study indicate that Dermatix is a useful treatment for the management of abnormal scarring
Contractubex showed best results in the prevention of pathological scars .
BACKGROUND The treatment and prevention of  hypertrophic scars and keloids  represents a special challenge particularly in plastic surgery .
Given their simple , non-invasive and painless application , topical preparations are an attractive therapeutic option .
On the part of the patients , the efficacy in prevention of and therapy for hypertrophic scars and keloids of these topical preparations is regularly question ed .
The clarification of this issue is subject of this review .