Summary Vitamin K may affect  bone mineral density and fracture incidence .
Since publication of a previous systematic review the integrity of some of the previous evidence has been question ed and further trials have been published .
Introduction This systematic review was design ed to assess the effectiveness of oral vitamin K supplementation for increasing bone mineral density  and reducing fractures in adults .
Risedronate therapy for prevention of hip fracture after stroke in elderly women [RETRACTED]
BACKGROUND There is a high incidence of hip fractures in patients with hemiplegic stroke .  Bone mineral density ( BMD ) is decreased in the hemiplegic side in patients after stroke , correlating with the degree of paralysis and of hypovitaminosis D. OBJECTIVE To evaluate the efficacy of risedronate in reducing the severity of osteoporosis and in decreasing the risk of hip fractures in elderly women following an acute stroke . METHODS This was a 12-month , r and omized , double blind , placebo-controlled trial . In a prospect i ve study of stroke patients , 187 patients received a daily dose of 2.5 mg risedronate for 12 months , and the remaining 187 received placebo .  Incidence of hip fracture was compared between the two groups at the endpoint of the study . RESULTS Seven patients sustained hip fractures on the hemiplegic side in the placebo group , and one hip fracture occurred in the risedronate group ( p = 0.0360 ; OR = 7.0 ) . BMD increased by 1.5 % and decreased by 4.9 % in the risedronate group and placebo group ( p < 0.0001 ) . Urinary deoxypyridinoline , a bone resorption marker , decreased by 53.4 % in the risedronate group and increased by 35.8 % in the placebo group . CONCLUSION Treatment with risedronate increases bone mineral density in elderly women following an acute stroke and prevents hip fractures
Summary Vitamin K may affect  bone mineral density and fracture incidence .
Since publication of a previous systematic review the integrity of some of the previous evidence has been question ed and further trials have been published .
Introduction This systematic review was design ed to assess the effectiveness of oral vitamin K supplementation for increasing bone mineral density  and reducing fractures in adults .