While the results of this systematic review are promising , there is insufficient evidence to draw conclusions on the effectiveness of text message-based interventions for adherence to medications for secondary prevention of CVD .
BACKGROUND Worldwide at least 100 million people are thought to have prevalent cardiovascular disease ( CVD ) .
This population has a five times greater chance of suffering a recurrent cardiovascular event than people without known CVD .
Secondary CVD prevention is defined as action aim ed to reduce the probability of recurrence of such events .
Drug interventions have been shown to be cost-effective in reducing this risk and are recommended in international guidelines .
However , adherence to recommended treatments remains sub-optimal .
In order to influence non-adherence , there is a need to develop scalable and cost-effective behaviour-change interventions .
OBJECTIVES To assess the effects of mobile phone text messaging in patients with established arterial occlusive events on adherence to treatment , fatal and non-fatal cardiovascular events , and adverse effects .
Text Messaging to Improve Hypertension Medication Adherence in African Americans: BPMED Intervention Development and Study Protocol
Background Hypertension ( HTN ) is a major public health concern in the United States , with almost 78 million Americans age 20 years and over suffering from the condition . Moreover , HTN is a key risk factor for health disease and stroke . African Americans disproportionately shoulder the burdens of HTN , with greater prevalence , disease severity , earlier onset , and more HTN-related complications than age-matched whites . Medication adherence for the treatment of HTN is poor , with estimates indicating that only about half of hypertensive patients are adherent to prescribed medication regimens . Although no single intervention for improving medication adherence has emerged as superior to others , text message medication reminders have the potential to help improve medication adherence in African Americans with uncontrolled HTN as mobile phone adoption is very high in this population . Objective The purpose of this two-phased study was to develop ( Phase I ) and test in a r and omized controlled trial ( RCT ) ( Phase II ) a text message system , BPMED , to improve the quality of medication management through increasing medication adherence in African Americans with uncontrolled HTN . Methods In Phase I , we recruited 16 target end-users from a primary care clinic , to assist in the development of BPMED through participating in one of three focus groups . Focus groups sought to gain patient perspectives on HTN , medication adherence , mobile phone use , and the use of text messaging to support medication adherence . Potential intervention design s were presented to participants , and feedback on the design s was solicited . In Phase II , we conducted two pilot RCTs to determine the feasibility , acceptability , and preliminary efficacy of BPMED in primary care and emergency department setting s. Both pilot studies recruited approximately 60 participants , who were r and omized equally between usual care and the BPMED intervention . Results Although data collection is now complete , data analysis from the two pilot RCTs is still ongoing and results are expected in 2015 . Conclusions This study was design ed to determine preliminary feasibility and acceptability of our approach among African Americans with uncontrolled HTN in primary care and emergency department setting s. Results from these studies are of great interest as little work has been done to document the use of text message medication reminders to improve HTN-related outcomes , particularly within underserved urban minorities . Trial Registration Clinical trials.gov NCT01465217 ; https:// clinical trials.gov/ct2/show/NCT01465217 ( Archived by WebCite at http://www.webcitation.org/6V0tto0lZ )
While the results of this systematic review are promising , there is insufficient evidence to draw conclusions on the effectiveness of text message-based interventions for adherence to medications for secondary prevention of CVD .
BACKGROUND Worldwide at least 100 million people are thought to have prevalent cardiovascular disease ( CVD ) .
This population has a five times greater chance of suffering a recurrent cardiovascular event than people without known CVD .
Secondary CVD prevention is defined as action aim ed to reduce the probability of recurrence of such events .
Drug interventions have been shown to be cost-effective in reducing this risk and are recommended in international guidelines .
However , adherence to recommended treatments remains sub-optimal .
In order to influence non-adherence , there is a need to develop scalable and cost-effective behaviour-change interventions .
OBJECTIVES To assess the effects of mobile phone text messaging in patients with established arterial occlusive events on adherence to treatment , fatal and non-fatal cardiovascular events , and adverse effects .