Overall , intervention groups obtained higher 25(OH)D concentration than controls and there was obvious dose – response effect between intake dose and 25(OH)D concentration .
Baseline 25(OH)D concentration and age were significant indicators for 25(OH)D concentration .
Conclusions Regional- and age-specific recommended dosages of VitD supplements for population to achieve optimal 25(OH)D concentrations have been suggested
Background / Objectives Optimal doses of vitamin D ( VitD ) supplement in different population s are unclear .
We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [ 25(OH)D ] concentration , to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different population s .
Prevalence of osteoporosis in ambulatory postmenopausal women from a semiurban region in Southern India: relationship to calcium nutrition and vitamin D status.
OBJECTIVE To assess the prevalence of osteoporosis in healthy ambulatory postmenopausal Indian women as measured by dual-energy x-ray absorptiometry and to study the dietary calcium intake and vitamin D status and their influence on bone mineral density ( BMD ) . METHODS We conducted a community-based cross-sectional study in a semiurban region . A r and omized cluster sampling technique was used . The study cohort consisted of 150 ambulatory postmenopausal women ( > or = 50 years old ) .  Dual-energy x-ray absorptiometry for BMD was performed at the lumbar spine and femoral neck . Dietary calcium intake and biochemical variables were assessed . RESULTS The prevalence of osteoporosis was 48 % at the lumbar spine , 16.7 % at the femoral neck , and 50 % at any site . The mean dietary calcium intake was much lower than the recommended intake for this age-group . There was a significant positive correlation between body mass index and BMD at the lumbar spine and the femoral neck ( r = 0.4 ; P = .0001 ) . BMD at the femoral neck was significantly less ( mean , 0.657 versus 0.694 g/cm(2 ) ) in the vitamin D-insufficient study subjects in comparison with the vitamin D-sufficient women ( P = .03 ) . CONCLUSION The high prevalence of osteoporosis and vitamin D insufficiency in this semiurban group of postmenopausal women in India is a major health concern . Measures such as adequate calcium intake and vitamin D supplementation in women of this age-group may be beneficial
Overall , intervention groups obtained higher 25(OH)D concentration than controls and there was obvious dose – response effect between intake dose and 25(OH)D concentration .
Baseline 25(OH)D concentration and age were significant indicators for 25(OH)D concentration .
Conclusions Regional- and age-specific recommended dosages of VitD supplements for population to achieve optimal 25(OH)D concentrations have been suggested
Background / Objectives Optimal doses of vitamin D ( VitD ) supplement in different population s are unclear .
We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [ 25(OH)D ] concentration , to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different population s .