After the intervention , Hb concentration and serum ferritin concentration were both higher in the NaFeEDTA group compared with the control group .
Subgroup analysis indicated that a lower baseline Hb level was associated with a greater increase in Hb concentration .
No significant difference in serum Zn concentration was found .
We concluded that NaFeEDTA increased both Hb concentration and serum ferritin concentration substantially in Fe-deficient population s , and could be an effective Fe preparation to combat Fe deficiency
Iron absorption in man: ascorbic acid and dose-dependent inhibition by phytate.
The dose-dependent inhibitory effect of sodium phytate on  iron absorption  was studied in man by serving wheat rolls containing no phytates and rolls  to which various amounts  ( seven dose levels between 2 and 250 mg expressed as phytate phosphorus ) were added just before serving . Fe in the two kinds of rolls was labeled with two radioisotopes of Fe ( 55Fe , 59Fe ) and the rolls were served on alternate days . The inhibition of Fe absorption was strongly related to the amount of phytate added ; 2 mg inhibited absorption by 18 % , ( p less than 0.001 ) , 25 mg by 64 % ( p less than 0.001 ) , and 250 mg by 82 % ( p less than 0.001 ) . The addition of ascorbic acid significantly counteracted the inhibition whereas the corresponding effect of meat was less well defined and only seen at the highest phytate level . The marked inhibition of Fe absorption by phytates and the significant counteracting effect of ascorbic acid have wide nutritional implication
After the intervention , Hb concentration and serum ferritin concentration were both higher in the NaFeEDTA group compared with the control group .
Subgroup analysis indicated that a lower baseline Hb level was associated with a greater increase in Hb concentration .
No significant difference in serum Zn concentration was found .
We concluded that NaFeEDTA increased both Hb concentration and serum ferritin concentration substantially in Fe-deficient population s , and could be an effective Fe preparation to combat Fe deficiency