A well-implemented ERAS protocol with good compliance is associated with a reduction in medical complications and length of hospital stay .
Enhanced recovery after surgery ( ERAS ) pathways are now implemented worldwide with strong evidence that adhesion to such protocol reduces medical complications , costs and hospital stay .
This concept has been applied for pancreatic surgery since the first published guidelines in 2012 .
This study presents the up date d ERAS recommendations for  pancreatoduodenectomy ( PD )  based on the best available evidence and on expert consensus .
Octreotide Does Not Prevent Pancreatic Fistula Following Pancreatoduodenectomy in Patients with Soft Pancreas and Non-dilated Duct: A Prospective Randomized Controlled Trial
Background Whether octreotide prevents pancreatic fistula following pancreatoduodenectomy is controversial and it is believed to be beneficial in soft gl and s and normal-sized ducts . The aim of this study is to assess the potential value of octreotide in reducing the incidence of pancreatic fistula , postoperative complications , morbidity and hospital stay in patients with soft pancreas and non-dilated ducts . Methods A total of 109 patients undergoing elective pancreatoduodenectomy with soft pancreas and non-dilated duct were r and omized to  octreotide group versus no octreotide —  the control group . Surgical steps were st and ardized and incidences of pancreatic fistula , complications , death and hospital stay were assessed . Results There were 55 patients in  octreotide group and 54 in the control group . Demographic features and pancreatic duct diameter of the groups were comparable . The rates of clinical ly significant pancreatic fistulae ( grade s B and C ) were 10.9 and 18.5 % ( p = ns ) , and morbidity was 18 and 29.6 % ( p = ns ) , respectively . Patients who received octreotide resumed oral diet early and had a shorter hospital stay . Conclusion This study demonstrated no statistical difference in pancreatic fistulae with the use of octreotide , though there was a trend towards fewer incidences of pancreatic fistulae , morbidity and shorter hospital stay . Clinical Trials.gov Identifier :
A well-implemented ERAS protocol with good compliance is associated with a reduction in medical complications and length of hospital stay .
Enhanced recovery after surgery ( ERAS ) pathways are now implemented worldwide with strong evidence that adhesion to such protocol reduces medical complications , costs and hospital stay .
This concept has been applied for pancreatic surgery since the first published guidelines in 2012 .
This study presents the up date d ERAS recommendations for  pancreatoduodenectomy ( PD )  based on the best available evidence and on expert consensus .