Conclusions : According to the published literature , the clinimetric properties of HAM-D6 are superior to those of both the HAM-D17 and MADRS .
Background : In a study aim ed at identifying the items carrying information regarding the global severity of depression , the 6-item Hamilton Depression Rating Scale ( HAM-D6 ) was derived from the original 17-item version of the scale ( HAM-D17 ) .
Since then , the HAM-D6 has been used in a wide range of clinical studies .
We now provide a systematic review of the clinimetric properties of HAM-D6 in comparison with those of HAM-D17 and the Montgomery Asberg Depression Rating Scale ( MADRS ) .
A double-blind comparison of gepirone extended release, imipramine, and placebo in the treatment of outpatient major depression.
We report the results from one site of a two-site , double-blind , placebo-controlled comparison study of gepirone extended release ( ER ) and imipramine in the management of major depression . In the study , 123 subjects with DSM-III-R major depression were r and omized to 8 weeks of treatment with gepirone ER ( 10 - 60 mg/day ) , imipramine ( 50 - 300 mg/day ) , or placebo . According to last observation carried forward ( LOCF ) analyses of 120 intent-to-treat subjects , both gepirone ER and imipramine were superior to placebo at Weeks 6 and 8 on the Hamilton Rating Scale for Depression 17- and 28-item ( HAM-D-17 and HAM-D-28 ) instruments , the Clinical Global Impressions ( CGI ) Severity of illness scale , and the total Bech Six-Item Core Depression Cluster score .  Gepirone ER was better tolerated than imipramine when judged by dropout rates for adverse events
Conclusions : According to the published literature , the clinimetric properties of HAM-D6 are superior to those of both the HAM-D17 and MADRS .
Background : In a study aim ed at identifying the items carrying information regarding the global severity of depression , the 6-item Hamilton Depression Rating Scale ( HAM-D6 ) was derived from the original 17-item version of the scale ( HAM-D17 ) .
Since then , the HAM-D6 has been used in a wide range of clinical studies .
We now provide a systematic review of the clinimetric properties of HAM-D6 in comparison with those of HAM-D17 and the Montgomery Asberg Depression Rating Scale ( MADRS ) .