We found a strong level of evidence for a relationship between depression and knee pain , limited evidence for no relationship between anxiety and knee pain , and minimal evidence for no relationship between poor mental health and knee pain .
Conclusions Despite the heterogeneity of the included studies , these data show that depression plays a significant role in knee pain , and that a biopsychosocial approach to the management of this condition is integral to optimising outcomes for knee pain
Background While it is recognized that psychosocial factors are important in the development and progression of musculoskeletal pain and disability , no systematic review has specifically focused on examining the relationship between psychosocial factors and knee pain .
We aim ed to systematic ally review the evidence to determine whether psychosocial factors , specifically depression , anxiety and poor mental health , are risk factors for knee pain .
Reciprocal relationship between pain and depression: a 12-month longitudinal analysis in primary care.
UNLABELLED Pain and depression are the most prevalent physical and psychological symptom-based disorders , respectively , and co-occur 30 to 50 % of the time . However , their reciprocal relationship and potentially causative effects on one another have been inadequately studied . Longitudinal data analysis involving 500 primary care patients with persistent back , hip , or knee pain were enrolled in the Stepped Care for Affective Disorders and Musculoskeletal Pain ( SCAMP ) study . Half of the participants had comorbid depression and were r and omized to a stepped care intervention ( n = 123 ) or treatment as usual ( n = 127 ) . Another 250 nondepressed patients with similar pain were followed in a parallel cohort . Outcomes were assessed at baseline , 3 , 6 , and 12 months . Mixed effects model repeated measures ( MMRM ) multivariable analyses were conducted to determine if change in pain severity predicted subsequent depression severity , and vice versa . Change in pain was a strong predictor of subsequent depression severity ( t-value = 6.63 , P < .0001 ) . Likewise , change in depression severity was an equally strong predictor of subsequent pain severity ( t-value = 7.28 , P < .0001 ) . Results from the full cohort were similar in the clinical trial subgroup . In summary , pain and depression have strong and similar effects on one another when assessed longitudinally over 12 months . PERSPECTIVE This study strengthens the evidence for a bidirectional and potentially causative influence of pain and depression on one another . A change in severity of either symptom predicts subsequent severity of the other symptom . Thus , recognition and management of both conditions may be warranted , particularly when treatment focused on 1 condition is not leading to an optimal response
We found a strong level of evidence for a relationship between depression and knee pain , limited evidence for no relationship between anxiety and knee pain , and minimal evidence for no relationship between poor mental health and knee pain .
Conclusions Despite the heterogeneity of the included studies , these data show that depression plays a significant role in knee pain , and that a biopsychosocial approach to the management of this condition is integral to optimising outcomes for knee pain
Background While it is recognized that psychosocial factors are important in the development and progression of musculoskeletal pain and disability , no systematic review has specifically focused on examining the relationship between psychosocial factors and knee pain .
We aim ed to systematic ally review the evidence to determine whether psychosocial factors , specifically depression , anxiety and poor mental health , are risk factors for knee pain .