Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .
Cow's milk IgE and IgG antibody responses to cow's milk formulas
For comparison of the antigenicity and allergenicity of three cow 's milk formulas , serum IgE antibodies to cow 's milk , β‐lactoglobulin and casein , and IgG antibodies to β‐lactoglobulin were analyzed in 94 infants with a family history of allergy . They were participating in a r and omized trial comparing the allergy prophylactic effect of feeding an extensively hydrolyzed ( N ) , a partially hydrolyzed ( PH ) , and a regular cow 's milk formula ( RM ) .  Only infants who had been formula‐fed for 3 months or more were included . IgE antibodies to cow 's milk proteins were more common in the RM group ( 22/34 ) than in the N ( 2/31 ) and PH groups ( 3/29 ) . There was a strong correlation between sensitization to cow 's milk and β‐lactoglobulin ( r=0.85 , P<0.001 ) . The IgG responses to β‐lactoglobulin were low in the N group , intermediate in the PH group , and high in the RM group . High responses , as well as detection of IgE antibodies , were associated with development of atopic disease . The low antigenicity and allergenicity of the extensively hydrolyzed formula support its use in allergy prophylaxis . The partial hydrolysate seemed to be less suitable for this purpose
Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .