Conclusions Inositol supplementation may result in reduction in triglycerides , total- and LDL-cholesterol levels , but did not affect HDL-cholesterol levels  among patients with metabolic diseases .
Background Several studies have evaluated the effect of inositol supplementation on lipid profiles among population with metabolic diseases ; however , the findings are controversial .
This review of r and omized controlled trials ( RCTs ) was performed to summarize the evidence of the effects of inositol supplementation on lipid profiles among population with metabolic diseases .
Effects of pinitol isolated from soybeans on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: a randomized controlled study
Objective : To assess the effects of soybean-derived pinitol on glycaemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus . Design : R and omized , double-blind , placebo-controlled , parallel-group trial . Setting : Pusan Paik Hospital , Pusan , Republic of Korea . Interventions : A total of 30 patients with type II diabetes received an oral dose of 600 mg soybean-derived pinitol or placebo twice daily for 13 weeks . Results : Pinitol significantly decreased mean fasting plasma glucose , insulin , fructosamine , HbA1c , and the homeostatic model assessment insulin resistance index ( HOMA-IR , P<0.001 ) . Pinitol significantly decreased total cholesterol , LDL-cholesterol , the LDL/HDL-cholesterol ratio , and systolic and diastolic blood pressure and increased HDL-cholesterol ( P<0.05 ) . Conclusions : These data suggest that soybean-derived pinitol may be beneficial in reducing cardiovascular risk in Korean type II diabetes . Sponsorship : This study was supported by a grant of the Korea Health 21 R&D Project , Ministry of Health & Welfare , Republic of Korea ( HMP 02-PJ1-PG3 - 22005 - 0011 )
Conclusions Inositol supplementation may result in reduction in triglycerides , total- and LDL-cholesterol levels , but did not affect HDL-cholesterol levels  among patients with metabolic diseases .
Background Several studies have evaluated the effect of inositol supplementation on lipid profiles among population with metabolic diseases ; however , the findings are controversial .
This review of r and omized controlled trials ( RCTs ) was performed to summarize the evidence of the effects of inositol supplementation on lipid profiles among population with metabolic diseases .