PRT had a large positive effect on strength ( 41 trials , 1955 participants ) , but there was statistical heterogeneity that was not explained by differences in study quality , participant characteristics or the exercise program .
REVIEW ER 'S CONCLUSIONS PRT appears to be an effective intervention to increase strength in older people and has a positive effect on some functional limitations .
However , the effect of this intervention on more substantive outcomes such as measures of disability or HRQOL remains unclear .
BACKGROUND Muscle weakness in old age , is associated with physical disability and an increased risk of falls .
Progressive resistance strength ( PRT ) training exercises ( i.e. movements performed against a specific external force that is regularly increased during training ) are design ed to increase strength in older people .
OBJECTIVES To assess the effect of PRT on measures of physical disability , functional limitation and impairment in older people  , and identify adverse events .
Effect of intensive exercise on patients with active rheumatoid arthritis: a randomised clinical trial
OBJECTIVE To investigate the effects of a dynamic , intensive exercise regimen on pain , disease activity , and physical functioning in active rheumatoid arthritis ( RA ) . METHODS 64 patients with RA with a mean age of 60 ( 13 ) years and mean disease duration of 8 ( 8) years , admitted to hospital because of active disease , were r and omly assigned to an  intensive exercise programme or to a  conservative exercise programme during their period in hospital with a mean length of 30 ( 14 ) days . The intensive exercise programme consisted of knee and shoulder dynamic and isometric muscle strengthening exercises against resistance five times a week and conditioning bicycle training three times a week and was supplemental to the conservative exercise programme of range of motion and isometric exercises . Indices of disease activity , pain , muscle strength , and functional ability were assessed at 0 , 3 , 6 , 12 , and 24 weeks by a blinded observer . RESULTS The medical treatment during the study was the same in both groups . Both groups improved in measures of disease activity , differences between groups were not statistically significant . The mean improvement in disease activity score at 24 weeks in the intensive and conservative exercise group was −1.4 ( 1.5 ) and −0.7 ( 1.4 ) , respectively . Measures of physical functioning improved significantly for patients in the intensive exercise group , and differences between groups were statistically significant for measures of muscle strength . CONCLUSION A short term intensive exercise programme in active RA is more effective in improving muscle strength than a conservative exercise programme and does not have deleterious effects on disease activity
PRT had a large positive effect on strength ( 41 trials , 1955 participants ) , but there was statistical heterogeneity that was not explained by differences in study quality , participant characteristics or the exercise program .
REVIEW ER 'S CONCLUSIONS PRT appears to be an effective intervention to increase strength in older people and has a positive effect on some functional limitations .
However , the effect of this intervention on more substantive outcomes such as measures of disability or HRQOL remains unclear .
BACKGROUND Muscle weakness in old age , is associated with physical disability and an increased risk of falls .
Progressive resistance strength ( PRT ) training exercises ( i.e. movements performed against a specific external force that is regularly increased during training ) are design ed to increase strength in older people .
OBJECTIVES To assess the effect of PRT on measures of physical disability , functional limitation and impairment in older people  , and identify adverse events .