Collectively , these outcomes support a volumetric dilution of vitamin D. The slopes of the respective regression lines , however , indicate a smaller increase in 25OHD than would be expected from a direct mobilization of stores into the circulation .
Hence , sequestration of 25OHD and its conversion to inactive metabolites would also play a role .
The purpose of this review was to confirm a volumetric dilution of vitamin D in obesity .
It was based on the hypothesis that weight loss , particularly fat loss , would increase serum 25-hydroxyvitamin D ( 25OHD ) in the obese .
Vitamin D status modification by two slightly hypocaloric diets in young overweight/obese women.
Obesity has been linked with poorer vitamin D status . The aim of this work was to analyze the changes in vitamin D status and body weight of 61 young , overweight/obese women following two different weight control programs . The study subjects were r and omly assigned to one of two slightly hypocaloric diets : diet V , in which the consumption of greens and vegetables was increased , or diet C , in which the consumption of cereals ( some of which were enriched with vitamin D ) was increased .  Dietary , anthropometric , and biochemical data were collected at the start of the study and at 2 weeks . At the beginning of the study , when taking into account only those women with a vitamin D intake below that recommended , obese women had a significantly lower mean serum 25(OH)D concentration than those who were lighter . Dietary intervention led to a greater reduction in energy intake among group C subjects ; their weight was also that which was most reduced . In addition , the vitamin D intake and serum 25(OH)D values were increased only in group C women . Excess body weight was associated with deterioration in vitamin D status , especially when the intake of this vitamin was lower than that recommended . Subjects with higher serum vitamin D at the beginning of the study lost more weight than those subjects with lower initial values . Diet C was associated with a greater weight loss than diet V , and led to a greater increase in vitamin D intake and serum 25(OH)D levels . This might be of interest in the improvement of health in people trying to lose weight
Collectively , these outcomes support a volumetric dilution of vitamin D. The slopes of the respective regression lines , however , indicate a smaller increase in 25OHD than would be expected from a direct mobilization of stores into the circulation .
Hence , sequestration of 25OHD and its conversion to inactive metabolites would also play a role .
The purpose of this review was to confirm a volumetric dilution of vitamin D in obesity .
It was based on the hypothesis that weight loss , particularly fat loss , would increase serum 25-hydroxyvitamin D ( 25OHD ) in the obese .