Where data were available , the relative benefits seen held true both after a single or multiple procedure(s ) .
For patients with persistent atrial fibrillation , CA achieves significantly greater freedom from recurrent atrial fibrillation compared with medical therapy .
BACKGROUND Catheter ablation ( CA ) is commonly performed for persistent atrial fibrillation , but few high- quality r and omized controlled trials ( RCTs ) exist , leading to funding restrictions being proposed in several countries .
We performed a r and om-effects meta- analysis of RCTs and non- RCTs to assess the efficacy of CA for persistent atrial fibrillation .
Additional left atrial septal line does not improve outcome of patients undergoing ablation for long-standing persistent atrial fibrillation
Objective — Additional septal linear ablation in patients undergoing ablation of long-st and ing persistent atrial fibrillation ( AF ) could be beneficial due to additional extensive atrial tissue ablation and incidental ablation of sites with complex fractionated electrograms . We assessed the long-term outcome of patients after ablation of long-st and ing persistent AF with an additional left atrial ( LA ) septal line . Methods — Thirty-four patients were included . The patients were r and omized into two groups and underwent pulmonary vein ( PV ) isolation with roof line , mitral isthmus line and coronary sinus ablation . In group 1 an additional LA septal line was created . Results — AF converted into atrial tachycardia in 2 patients during septal ablation in group 1 . In group 2 AF terminated via atrial tachycardia in 3 patients ( P = ns ) . During a mean follow-up of 620 ± 119 days , 7 ( 41 % ) and 8 ( 47 % ) patients from group 1 and group 2 were free from recurrences ( P = ns ) . Redo procedures were performed in 5 patients of group 1 and in 5 patients of group 2 . For a follow-up of 349 ± 273 days after the last ablation , Cox ’s F-test showed a trend of more recurrences in group 1 ( P = 0.07 ) . Conclusions — In patients with long-st and ing AF , an additional LA septal linear ablation is not associated with a significantly higher AF termination rate . A septal linear lesion might increase the risk of septal reentrant tachycardias , and is associated with a trend towards a worse outcome
Where data were available , the relative benefits seen held true both after a single or multiple procedure(s ) .
For patients with persistent atrial fibrillation , CA achieves significantly greater freedom from recurrent atrial fibrillation compared with medical therapy .
BACKGROUND Catheter ablation ( CA ) is commonly performed for persistent atrial fibrillation , but few high- quality r and omized controlled trials ( RCTs ) exist , leading to funding restrictions being proposed in several countries .
We performed a r and om-effects meta- analysis of RCTs and non- RCTs to assess the efficacy of CA for persistent atrial fibrillation .