“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .
Effect of xuezhikang, a cholestin extract, on reflecting postprandial triglyceridemia after a high-fat meal in patients with coronary heart disease.
The effect of xuezhikang on postpr and ial triglyceride ( TG ) level was investigated in patients with coronary heart disease ( CHD ) after a high-fat meal ( 800 cal ; 50 g fat ) . Fifty CHD patients were r and omly divided into two groups to accept xuezhikang ( xuezhikang group ) 1200 mg/day ( 600 mg twice daily ) or not ( control group ) on the base of routine therapy which included aspirin , metoprolol and fosinopril and nitrates during the whole 6 weeks following-up . Xuezhikang significantly reduced fasting serum total cholesterol ( TC ) ( -20 % ) , low-density lipoprotein cholesterol ( LDL-C , -34 % ) , TG ( -32 % ) and apoB ( -27 % ) levels , and raised fasting high-density lipoprotein cholesterol ( HDL-C , 18 % ) and apoA-I ( 13 % ) levels ( P<0.001 ) . The postpr and ial serum TG levels at 2 , 4 and 6 h decreased 32 , 38 and 43 % , respectively , in xuezhikang group ( P<0.001 ) . The TG area under the curve over the fasting TG level ( TG-AUC ) significantly decreased in CHD patients accepted xuezhikang with normal ( less than 1.7 mmol/l ) and elevated ( 1.74 to 2.92 mmol/l ) fasting TG levels by 45 and 50 % , respectively ( P<0.001 ) . Routine therapy had no significant effect on the fasting and postpr and ial lipid and apolipoprotein levels . The change of TG-AUC was significantly related to the changes of fasting TG , TC , LDL-C , and HDL-C levels after the treatment , which were related to the changes of fasting apoA-I and apoB levels significantly ( P<0.001 ) . Xuezhikang was shown to be beneficial in the treatment of reflecting postpr and ial triglyceridemia in CHD patients with normal and mildly elevated fasting TG levels
“ RYR plus conventional therapy ” exhibited significant lowering effects on serum total cholesterol ( TC ) , low-density lipoprotein cholesterol ( LDL-C ) , and CRP but exhibited no significant effect on systolic BP , diastolic BP , triglycerides ( TG ) , and high-density lipoprotein cholesterol ( HDL-C ) compared with “ placebo plus conventional therapy . ” “
RYR plus conventional therapy ” showed significant lowering effects on systolic BP , TC , LDL-C , and CRP but no effect on diastolic BP , TG , and HDL-C compared with “ placebo plus conventional therapy . ”
No significant difference in BP and lipid profile between “ RYR plus conventional therapy ” and “ statins plus conventional therapy ” was observed .
“ RYR plus statins ” appeared to be more effective in lowering BP , TC , TG , and LDL-C but without a significant difference in HDL-C compared to statins .
No serious adverse events were reported .
The results of this meta- analysis suggested some supportive but limited evidence regarding RYR for hypertension .
ABSTRACT Interest is increasing regarding the potential health effects of red yeast rice ( RYR ) consumption , which is described as a “ natural statin ” in China .
This review aims to evaluate the efficacy of RYR on blood pressure ( BP ) , lipid profile , and C-reactive protein ( CRP ) in treating  hypertension .