The National Eye Institute Visual Function Question naire-25 , Impact of Vision Impairment and Treatment Satisfaction Survey-Intraocular Pressure had the highest number of positive ratings in the content validity assessment .
Conclusion This study provides a descriptive catalogue of vision-specific PRO instruments , to inform the choice of an appropriate measure of patient-reported outcomes in a glaucoma context
Purpose To identify  vision Patient-Reported Outcomes instruments relevant to glaucoma and assess their content validity .
Switching patients with glaucoma or ocular hypertension from dual therapy to monotherapy: Evaluation of brimonidine as a model
A multicenter open-label study investigated the clinical effectiveness and economic feasibility of switching 142 patients from dual therapy to twice-daily monotherapy with brimonidine for glaucoma or ocular hypertension . Evaluations were performed at baseline and 2 ( visit 2 ) and 8 ( visit 3 ) weeks after the switch . Patients completed a question naire that rated medication-related visual function and satisfaction ( comfort , convenience , vision , ease of remembering to use drops ) at each visit . At visit 3 , investigators , taking into account IOP measurements , safety , and responses on the question naire , recommended whether the patient should remain on brimonidine . A pharmacoeconomic analysis , including the number of visits , cost of medication , and success rates , compared the cost of dual therapy with that of switching to brimonidine monotherapy . Of the 131 patients who completed the study , 77 ( 59 % ) had no change or a decrease in IOP from baseline , and 53 ( 41 % ) had an increase . Investigators recommended that 77 % of the study completers continue to take brimonidine monotherapy . Extending treatment with brimonidine for 12 months would achieve a significant cost savings of 16 % . Brimonidine monotherapy is an efficacious and cost-effective alternative to dual therapy for glaucoma and ocular hypertension . Appropriate monotherapy may be as effective as dual therapy for many patients , and a clinical ly relevant trial such as this may be economically advantageous for testing a switch
The National Eye Institute Visual Function Question naire-25 , Impact of Vision Impairment and Treatment Satisfaction Survey-Intraocular Pressure had the highest number of positive ratings in the content validity assessment .
Conclusion This study provides a descriptive catalogue of vision-specific PRO instruments , to inform the choice of an appropriate measure of patient-reported outcomes in a glaucoma context
Purpose To identify  vision Patient-Reported Outcomes instruments relevant to glaucoma and assess their content validity .