The cinnamon administrations significantly reduced FM at the dosages of ≥2 g/d , when administered for ≥12 weeks .
Cinnamon administration result ed in BW and WC reduction in non-linear fashion ( P = 0.04 ) .
Cinnamon supplementation significantly affects obesity measures .
BACKGROUND & AIMS Data about the effects of cinnamon supplementation on obesity measures are conflicting .
This systematic review and meta- analysis of r and omized controlled trials ( RCTs ) was conducted to summarize the effects of cinnamon intake on body weight ( BW ) , Body Mass Index ( BMI ) , Waist Circumference ( WC ) , and fat mass ( FM ) in adults .
Protective effects of cinnamon bark extract against ischemia–reperfusion injury and arrhythmias in rat
Cinnamomum zeylanicum ( cinnamon ) is a plant with potent antioxidant activity and has been used in traditional medicine for improvement of heart function . The effects of cinnamon bark ethanolic extract were investigated against ischemia-induced arrhythmias and heart injury in an in vivo rat model of regional heart ischemia . The extract was also st and ardized , and its antioxidant activity was evaluated . Adult male Sprague-Dawley rats were subjected to 30 min of ischemia by occlusion of the left anterior descending coronary artery followed by 5 days of reperfusion . Thirty-two animals were r and omized to receive daily oral administration of vehicle or C. zeylanicum bark extract ( intragastric , 50 , 100 , or 200 mg/kg ) 14 days before ischemia . C. zeylanicum was st and ardized through HPLC analysis . Administration of cinnamon bark extract significantly improved ischemia/reperfusion-induced myocardial injury as evidence d by reduction of the infa rct size . Also , during the ischemic period , ventricular tachycardia and ventricular ectopic beats episodes decreased as compared with that of the control group . The extract stabilized the ST segment changes and QTc shortening , decreased R-wave amplitude , and increased heart rate during ischemia . The extract also caused significant elevations in serum superoxide dismutase and glutation proxidase activities as well as a significant decrease in serum cardiac troponin I , lactate dehydrogenase , and malondialdehyde levels , 5 days after reperfusion . In HPLC analysis , the amounts of Cinamic acid , Methyl eugenol , and Cinnamaldehyde were 8.99 ± 0.5 , 13.02 ± 1.8 , and 14.63 ± 1.1 mg/g , respectively . The results show that the ethanolic extract of cinnamon bark is able to protect the heart against ischemia-reperfusion injury probably due to its antioxidant properties . Hence , it might be beneficial in these patients and this remedy might be used for preparation of new drugs
The cinnamon administrations significantly reduced FM at the dosages of ≥2 g/d , when administered for ≥12 weeks .
Cinnamon administration result ed in BW and WC reduction in non-linear fashion ( P = 0.04 ) .
Cinnamon supplementation significantly affects obesity measures .
BACKGROUND & AIMS Data about the effects of cinnamon supplementation on obesity measures are conflicting .
This systematic review and meta- analysis of r and omized controlled trials ( RCTs ) was conducted to summarize the effects of cinnamon intake on body weight ( BW ) , Body Mass Index ( BMI ) , Waist Circumference ( WC ) , and fat mass ( FM ) in adults .