As for physical exercise modalities , aerobic exercise , but not other modalities , increased adiponectin and reduced leptin levels .
In conclusion , physical exercise and , specifically , aerobic exercise , leads to higher adiponectin and lower leptin levels  in prediabetic and diabetic adults .
It is speculated that lifestyle interventions known to improve diabetic metabolic state may exert their effects via adipokines .
The aim of this systematic review and meta- analysis was to evaluate the chronic effects of physical exercise on adiponectin and leptin levels in adult prediabetic and diabetic individuals .
Effects of aerobic and/or resistance training on body mass and fat mass in overweight or obese adults.
Recent guidelines on exercise for weight loss and weight maintenance include resistance training as part of the exercise prescription . Yet few studies have compared the effects of similar amounts of aerobic and resistance training on body mass and fat mass in overweight adults . STRRIDE AT/RT , a r and omized trial , compared aerobic training , resistance training , and a combination of the two to determine the optimal mode of exercise for obesity reduction . Participants were 119 sedentary , overweight or obese adults who were r and omized to one of three 8-mo exercise protocol s : 1 ) RT : resistance training , 2 ) AT : aerobic training , and 3 ) AT/RT : aerobic and resistance training ( combination of AT and RT ) . Primary outcomes included total body mass , fat mass , and lean body mass . The AT and AT/RT groups reduced total body mass and fat mass more than RT ( P < 0.05 ) , but they were not different from each other . RT and AT/RT increased lean body mass more than AT ( P < 0.05 ) . While requiring double the time commitment , a program of combined AT and RT did not result in significantly more fat mass or body mass reductions over AT alone . Balancing time commitments against health benefits , it appears that AT is the optimal mode of exercise for reducing fat mass and body mass , while a program including RT is needed for increasing lean mass in middle-aged , overweight/obese individuals
As for physical exercise modalities , aerobic exercise , but not other modalities , increased adiponectin and reduced leptin levels .
In conclusion , physical exercise and , specifically , aerobic exercise , leads to higher adiponectin and lower leptin levels  in prediabetic and diabetic adults .
It is speculated that lifestyle interventions known to improve diabetic metabolic state may exert their effects via adipokines .
The aim of this systematic review and meta- analysis was to evaluate the chronic effects of physical exercise on adiponectin and leptin levels in adult prediabetic and diabetic individuals .