OC could significantly reduce the occurrence of VAP , and consequently , its routine use should be considered for VLBWs to prevent infectious diseases .
OC  significantly reduces the occurrence of VAP and NEC in VLBW infants  .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP .
OC significantly reduces the occurrence of VAP and NEC in VLBW infants .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP
Oropharyngeal colostrum ( OC ) is a novel feeding strategy to prevent complications of prematurity .
A meta- analysis was conducted to investigate whether very low birth weight infants ( VLBWs ) can benefit from OC .
Ventilator-associated pneumonia in pediatric intensive care unit patients: risk factors and outcomes.
OBJECTIVES To determine the rates , risk factors , and outcomes of  ventilator-associated pneumonia in pediatric intensive care unit ( PICU ) patients . METHODS A prospect i ve cohort study was conducted at the St Louis Children 's Hospital PICU on all patients who were admitted to the PICU from September 1 , 1999 , to May 31 , 2000 , except those who died within 24 hours , were > or = 18 years of age , or were neonatal intensive care unit patients on extracorporeal membrane oxygenation . The primary outcome measured was the development of ventilator-associated pneumonia . Secondary outcomes were death and hospital and PICU length of stay .  Multiple logistic regression analysis was performed to determine independent predictors for ventilator-associated pneumonia . RESULTS There were 34 episodes of ventilator-associated pneumonia in 30 patients of 911 admissions ( 3.3 % ) and 595 ( 5.1 % ) mechanically ventilated patients . The mean ventilator-associated pneumonia rate was 11.6/1000 ventilator days . By logistic regression analysis , genetic syndrome ( odds ratio [ OR ] : 2.37 ; 95 % confidence interval [ CI ] : 1.01 - 5.46 ) , reintubation ( OR : 2.71 ; 95 % CI : 1.18 - 6.21 ) , and transport out of the PICU ( OR : 8.90 ; 95 % CI : 3.82 - 20.74 ) independently predicted ventilator-associated pneumonia . CONCLUSIONS Ventilator-associated pneumonia occurs at significant rates among mechanically ventilated PICU patients and is associated with processes of care . Additional studies are necessary to develop interventions to prevent ventilator-associated pneumonia
OC could significantly reduce the occurrence of VAP , and consequently , its routine use should be considered for VLBWs to prevent infectious diseases .
OC  significantly reduces the occurrence of VAP and NEC in VLBW infants  .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP .
OC significantly reduces the occurrence of VAP and NEC in VLBW infants .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP
Oropharyngeal colostrum ( OC ) is a novel feeding strategy to prevent complications of prematurity .
A meta- analysis was conducted to investigate whether very low birth weight infants ( VLBWs ) can benefit from OC .