Conclusions The current evidence is not sufficiently strong to verify a preventive role of probiotics in AR , but probiotics may improve the overall quality of life and nasal symptom scores .
Background Allergic rhinitis ( AR ) is a disease of respiratory allergy , and probiotics can provide a potential strategy for its management .
The purpose of this study was to carry out a systematic review to investigate the role of probiotics in the prevention and treatment of AR .
Treatment of perennial allergic rhinitis with lactic acid bacteria.
Probiotics are perceived to exert beneficial effects in the prevention and treatment of allergic diseases via modifying the gut ecosystem . The aim of this study was to assess whether ingestion of fermented milk containing Lactobacillus paracasei-33 ( LP-33 ) , a strain newly isolated from the human intestinal tract , can improve the quality of life of patients with perennial allergic rhinitis . In a r and omized , double-blind , placebo-controlled trial , we gave patients fermented milk with ( n = 60 ) or without ( n = 20 ) the addition of LP-33  ( 2 x 10(9 ) colony-forming units per bottle ) for 30 days . A modified question naire concerning pediatric rhinoconjunctivitis quality of life was administered to all subjects or their parents at each clinical visit . Scores for the overall quality of life significantly decreased in the LP-33 group as compared with the placebo group , in both frequency ( -16.02 + /- 2.14 vs. -7.27 + /- 3.55 , respectively ; p = 0.037 ) and level of bother ( -16.35 + /- 2.33 vs. -6.20 + /- 3.13 , respectively ; p = 0.022 ) after the 30-day treatment . Subjects reported no severe adverse effects such as fever , abdominal pain , or diarrhea . The results suggest that ingestion of LP-33-fortified fermented milk for 30 days can effectively and safely improve the quality of life of patients with allergic rhinitis , and may serve as an alternative treatment for allergic rhinitis
Conclusions The current evidence is not sufficiently strong to verify a preventive role of probiotics in AR , but probiotics may improve the overall quality of life and nasal symptom scores .
Background Allergic rhinitis ( AR ) is a disease of respiratory allergy , and probiotics can provide a potential strategy for its management .
The purpose of this study was to carry out a systematic review to investigate the role of probiotics in the prevention and treatment of AR .