Findings related to effectiveness ( treatment discontinuation , quality of life , and neurocognitive improvements ) were generally consistent with those observed in non-Chinese population s. No new safety signals specific for Chinese population s were raised for olanzapine .
Chinese and non-Chinese population s with schizophrenia or bipolar disorder treated with olanzapine display broadly similar responses .
BACKGROUND Despite the burden of schizophrenia and bipolar disorder in the Chinese population , country-specific data to guide practitioners regarding antipsychotic therapy are lacking .
Chinese authors do need CONSORT: reporting quality assessment for five leading Chinese medical journals.
OBJECTIVE Only a few Chinese medical journals have recommended CONSORT in their " Instruction for authors or Guide for authors " . This study aims to evaluate the reporting quality of r and omized  controlled trials ( RCTs ) published in the five leading Chinese medical journals indexed by MEDLINE . METHODS We identified RCTs published from 2004 to January 2007 in five leading Chinese medical journals by search ing three important Chinese data bases systematic ally , namely CNKI ( China National Knowledge Infrastructure/Chinese Academic Journals full text Data base ) , VIP ( a full text data base of China ) and CBM disc ( China Biomedicine Data base Disc ) and assessed the quality of each RCT by using the Consoli date d St and ards for Reporting of Trials ( CONSORT ) and the 5-point Jadad scale . RESULTS One hundred and forty two RCTs were included . Based on the items in the revised CONSORT statement , 130 ( 91.55 % ) of the 142 RCTs mentioned " r and omization " in the title or abstract , but only 38 ( 26.76 % ) RCTs described the method to generate the r and om sequence ; only 6 RCTs had adequate allocation concealment ; 24 ( 17.61 % ) RCTs mentioned " masking " , but only 7 described the process of masking . Three out of 40 items were reported clearly in all included trials , while five items were not mentioned at all . The quality of RCTs was low as assessed by the Jadad scale and 22 RCTs were high- quality research ( > /=3 points ) . CONCLUSIONS The reporting quality of RCTs published in the five leading Chinese medical journals is low . Chinese journals should adopt the CONSORT statement to improve the reporting quality of Chinese r and omized controlled trials
Findings related to effectiveness ( treatment discontinuation , quality of life , and neurocognitive improvements ) were generally consistent with those observed in non-Chinese population s. No new safety signals specific for Chinese population s were raised for olanzapine .
Chinese and non-Chinese population s with schizophrenia or bipolar disorder treated with olanzapine display broadly similar responses .
BACKGROUND Despite the burden of schizophrenia and bipolar disorder in the Chinese population , country-specific data to guide practitioners regarding antipsychotic therapy are lacking .