Preoperative and post-operative intensive interventions improved symptoms of depression and anxiety , quality of life , diastolic blood pressure , and resting heart rate but not lipids or glycaemic measures .
This systematic review and meta- analysis of intervention studies aims to evaluate the effect of preoperative and /or post-operative support for adults who elect bariatric surgery delivered by a multidisciplinary team ( MDT )  on post-operative body composition , mental health , co-morbidities , quality of life , and side effects .
Effects of gastric bypass followed by a randomized study of physical training on markers of coagulation activation, fibrin clot properties, and fibrinolysis.
BACKGROUND The risk of cardiovascular disease is reduced by bariatric surgery , but it is unknown if exercise after bariatric surgery reduces this risk even further . OBJECTIVE To investigate if Roux-en-Y-gastric bypass ( RYGB ) and supervised physical training after RYGB improve cardiovascular disease risk markers within coagulation activation , fibrin clot properties , and fibrinolysis . SETTING Bariatric center , Hospital of Southwest Jutl and , Denmark . METHODS Sixty obese patients underwent RYGB and 6 months after RYGB were r and omized to 26 weeks of physical training or  a control group .  Biomarkers within coagulation activation , fibrin clot properties , and fibrinolysis were measured presurgery , and 6 , 12 , and 24 months postsurgery . RESULTS Six months after RYGB , the endogenous thrombin potential decreased from 1744 ( 1603 - 2003 ) to 1416 ( 1276 - 1582 ) nM × min ( P<.001 ) . Alterations in fibrin clot properties result ed in an increased clot lysis from 23.8 % ( 16.1%-38.9 % ) to 40.3 % ( 28.5%-59.35 ; P<.0001 ) . Furthermore , fibrinogen was reduced from 12.6 ( 11.1 - 14.7 ) to 11.5 ( 9.90 - 13.3 ) µM ( P<.001 ) , and plasminogen activator inhibitor antigen was reduced from 40.5 ( 28.4 - 49.4 ) to 24.4 ( 15.4 - 32.7 ) ng/mL ( P<.0001 ) . Physical training after RYGB increased fibrinolytic activity from 58.0 ( 36.0 - 75.5 ) to 88.0 ( 66.0 - 132.0 ) IU/mL compared with 52.5 ( 30.0 - 80.0 ) to 64.0 ( 49.0 - 100.0 ) IU/mL in controls ( P<.01 ) and reduced plasminogen activator inhibitor antigen from 23.5 ( 16.7 - 35.4 ) to 18.1 ( 14.3 - 25.4 ) ng/mL compared with 24.4 ( 13.9 - 28.7 ) to 24.2 ( 14.1 - 29.6 ) ng/mL in controls ( P<.05 ) . No effects of physical training were observed on markers of coagulation activation and fibrin clot properties . CONCLUSION We observed favorable long-term reductions in markers of thrombin generation , improved fibrin clot properties , and increases in fibrinolysis after RYGB . Supervised physical training after RYGB further increased fibrinolysis
Preoperative and post-operative intensive interventions improved symptoms of depression and anxiety , quality of life , diastolic blood pressure , and resting heart rate but not lipids or glycaemic measures .
This systematic review and meta- analysis of intervention studies aims to evaluate the effect of preoperative and /or post-operative support for adults who elect bariatric surgery delivered by a multidisciplinary team ( MDT )  on post-operative body composition , mental health , co-morbidities , quality of life , and side effects .