There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Nutritional effect of including egg yolk in the weaning diet of breast-fed and formula-fed infants: a randomized controlled trial.
BACKGROUND Egg yolks can be a source of docosahexaenoic acid ( DHA ) and iron but are often associated with adverse consequences on plasma cholesterol . OBJECTIVE Our goal was to investigate the effect of consumption of 4 egg yolks/wk on infant DHA status and hemoglobin , ferritin , and plasma cholesterol concentrations . Secondary outcomes included plasma iron , transferrin , and transferrin saturation . DESIGN This was a r and omized controlled trial comparing no dietary intervention , consumption of 4 regular egg yolks/wk , and consumption of 4 n-3 fatty acid-enriched egg yolks/wk in breast-fed and formula-fed infants from 6 to 12 mo of age .  Erythrocyte DHA concentrations , cholesterol , and iron status were assessed at 6 and 12 mo of age . RESULTS Of the 82 breast-fed infants recruited , 23 of 28 ( no intervention ) , 23 of 27 ( regular eggs ) , and 24 of 27 ( n-3 eggs ) completed the trial . Of the 79 formula-fed infants enrolled , 23 of 27 ( no intervention ) , 24 of 26 ( regular eggs ) , and 20 of 26 ( n-3 eggs ) completed the trial .  Erythrocyte DHA concentrations were 30 - 40 % higher after the n-3 egg intervention than after treatment with regular eggs or no eggs in both breast-fed and formula-fed infants . Egg treatment had no significant effect on plasma cholesterol , hemoglobin , ferritin , and transferrin but did result in improvements in plasma iron and transferrin saturation compared with no egg treatment . CONCLUSIONS n-3 Fatty acid-enriched eggs may provide a means of increasing dietary DHA during the second 6 mo of life . Egg yolks may also be a useful source of iron during the weaning period and can be safely included in the weaning diet with no perturbations in plasma cholesterol
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .