Conclusions Piracetam plays a limited role in the rehabilitation of overall language impairment and only benefits written language ability at the end of trials .
Its effect on overall linguistic level and written language tends to emerge within a short period and declines thereafter
Background Aphasia is a common symptom in post-stroke patients .
Piracetam is a commonly used nootropic agent that promises various benefits to brain function , including language improvement .
Objective We performed a systematic review and meta- analysis to assess whether piracetam facilitates the rehabilitation of language performance in post-stroke patients .
Restitution of alpha-topography by piracetam in post-stroke aphasia.
OBJECTIVE Electroencephalographic and clinical effects of piracetam in post-stroke aphasia were evaluated in a prospect i ve , r and omized , double-blind , placebo-controlled trial . METHODS In 24 patients with mild to moderate aphasia after ischemic stroke , quantitative topographic EEG at rest was studied before and after a 6-week treatment period . RESULTS In the active treatment group , a significant shift in the alpha-rhythm from frontal to occipital regions was observed which may be due to a restitution of corticothalamic circuits involved in the generation of alpha-activity . CONCLUSION Neuropsychological scores improved significantly and markedly in various domains of speech during piracetam treatment , whereas improvements were less marked and restricted to a few categories in the placebo group
Conclusions Piracetam plays a limited role in the rehabilitation of overall language impairment and only benefits written language ability at the end of trials .
Its effect on overall linguistic level and written language tends to emerge within a short period and declines thereafter
Background Aphasia is a common symptom in post-stroke patients .
Piracetam is a commonly used nootropic agent that promises various benefits to brain function , including language improvement .
Objective We performed a systematic review and meta- analysis to assess whether piracetam facilitates the rehabilitation of language performance in post-stroke patients .