The posterolateral approach reported the lowest value for the surgical duration .
The posterolateral approach reported the shortest hospitalization length .
The posterolateral approach reported shorter surgical duration and hospitalization length .
Concerning the analysis of total estimated blood loss , no significant result was obtained .
Despite the numerous studies , there is no consensus concerning the best approach for  total hip arthroplasty ( THA )  , and debates are ongoing .
The purpose of this study was to perform a Bayesian network meta- analysis ( NMA ) comparing several approaches for primary THA .
The focus was on peri-operative outcomes : surgical duration , total estimated blood loss , and length of the hospitalization .
Posterolateral vs Direct Anterior Approach in Total Hip Arthroplasty (POLADA Trial): A Randomized Controlled Trial to Assess Differences in Serum Markers.
BACKGROUND The direct anterior approach ( DAA ) for total hip arthroplasty has cl aim ed to be a true tissue-sparing minimally invasive approach that has less tissue damage and a faster recovery when compared to the posterolateral approach ( PLA ) . The aim of this r and omized controlled trial is to measure the differences in serum markers and functional outcomes between the DAA and PLA for total hip arthroplasty . METHODS Forty-six patients were prospect ively included and r and omized for either the DAA ( n = 23 ) or PLA ( n = 23 ) . All surgical procedures were performed by 3 well-trained orthopedic surgeons . The degree of tissue damage was assessed by measuring creatine kinase ( CK ) and C-reactive protein levels ( CRP ) preoperatively and 2 hours , 1 day , 2 weeks , and 6 weeks postoperatively . Generalized linear mixed models analyses were used to assess differences between serum markers over time ; correction for possible confounding factors was performed . The Hip disability and Osteoarthritis Outcome Score and the Harris Hip Score were assessed preoperatively and 6 weeks postoperatively . RESULTS There were no differences in patient demographics . The DAA had a longer operative time ( P = .001 ) . CK and CRP levels increased postoperatively , but no significant differences between the groups were found on any of the time points . Functional outcomes were also similar in both approaches . CONCLUSION No difference in tissue damage measured with serum markers CK and CRP were found between the DAA and PLA for total hip arthroplasty
The posterolateral approach reported the lowest value for the surgical duration .
The posterolateral approach reported the shortest hospitalization length .
The posterolateral approach reported shorter surgical duration and hospitalization length .
Concerning the analysis of total estimated blood loss , no significant result was obtained .
Despite the numerous studies , there is no consensus concerning the best approach for  total hip arthroplasty ( THA )  , and debates are ongoing .
The purpose of this study was to perform a Bayesian network meta- analysis ( NMA ) comparing several approaches for primary THA .
The focus was on peri-operative outcomes : surgical duration , total estimated blood loss , and length of the hospitalization .