Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .
Can post-operative antibiotic prophylaxis following elective laparoscopic cholecystectomy be completely done away with in the Indian setting? A prospective randomised study
Premise and Objective : Elective laparoscopic cholecystectomy ( LC ) has low risk for post-operative infectious complications ; still most clinicians use persistent post-operative prophylactic antibiotics out of habit , tradition , or simply as defensive practice due to evolving medicolegal implication s of a large number of surgeries being showcased as daycare or next day discharge procedures . This r and omised prospect i ve trial was done to test the need for such prophylaxis in cases of elective LC in a rural/semi-urban setting . Material s and Methods : Two hundred and ten successive patients undergoing elective LC were r and omised into groups receiving single dose of injection ceftriaxone at the time of induction of anaesthesia , ( Group A = 112 cases ) and those who in addition to above received injection ceftriaxone twice daily for 2 days postoperatively ( Group B = 98 cases ) . Post-operative infectious complications between two groups were compared for variables such as age , sex , body mass index and bile/stone spillage . Results : There was no significant difference in surgical site infection rates between the groups for variables such as age , sex , body mass index , duration of symptoms , American Society of Anesthesiologists grade , duration of surgery and hospital stay . Intraoperative spillage of stones ( 9.8 % [ A ] : 5.1 % [ B ] ) did not increase infectious complications even in the presence of positive bile culture ( Group A , N = 7 vs. Group B , N = 3 ) . An operative time of greater than 60 min was found to be associated with increased surgical site infection ( P = 0 . 0006 ) . Conclusion : Single dose of ceftriaxone at the time of induction is adequate prophylaxis following elective LC even in the rural/semi-urban Indian setting and routine continued administration of antibiotic should be ab and oned as it contributes to adverse reactions , drug resistance and unnecessary financial burden
Conclusions The use of prophylactic antibiotics is effective for reducing the incidence of SSI and superficial SSI but is not effective for preventing deep SSI in low-risk patients who underwent elective laparoscopic cholecystectomy
Background s/ Aims The role of prophylactic antibiotics for laparoscopic cholecystectomy in low-risk patients is still unclear .
This study aim ed to verify the conclusion of previous meta-analyses concerning the effectiveness of antibiotic prophylaxis for elective laparoscopic cholecystectomy in low-risk patients .