The pooled estimate from the studies suggested that the addition of testosterone to HT regimens improved sexual function scores for postmenopausal women .
A significant adverse effect was a decrease in high-density lipoprotein ( HDL ) cholesterol levels .
However , there is evidence that adding testosterone to HT has a beneficial effect on sexual function in postmenopausal women .
There was a reduction in HDL cholesterol associated with the addition of testosterone to the HT regimens .
It is , therefore , difficult to estimate the effect of testosterone on sexual function in association with any individual hormone treatment regimen
BACKGROUND : The value of adding testosterone to hormone therapy ( HT ) for the management of peri- and postmenopausal women is controversial and has not been systematic ally review ed .
OBJECTIVES : To determine the benefits and risks of testosterone therapy for peri- and postmenopausal women taking hormone therapy .
Neuropsychological effects of methyltestosterone in women using menopausal hormone replacement.
To observe the effects of and rogen replacement on neuropsychological measures in menopausal women , healthy menopausal women already using replacement estrogen  were studied in a r and omized , double-blind , active placebo-controlled , crossover comparison between two 8-week periods of treatment with ( 1 ) 0.625 mg oral esterified estrogen ( E ) alone and ( 2 ) in combination with 1.25 mg oral methyltestosterone ( meT ) . After an initial baseline session , data were gathered at the end of two treatment periods . Scores on st and ardized psychological tests and computerized reaction times were compared between treatments , as was an overall outcome score that combined all measures . Added meT significantly improved scores on a test of complex information processing , the Switching Attention Test , but not on other tests . Mean outcome score showed no net change and wide variation . Fourteen subjects had outcome scores > 1 SD from the mean , and 21 had no change . In the estrogen alone condition , three measures predicted favorable outcome with added meT : surgically compromised ovarian function , fewer physical symptoms , and higher score on a self-image measure of creativity . Added meT treatment may improve complex information processing . Despite wide disparities in outcome , an increased chance of overall improvement may be predicted by specific pretreatment measures
The pooled estimate from the studies suggested that the addition of testosterone to HT regimens improved sexual function scores for postmenopausal women .
A significant adverse effect was a decrease in high-density lipoprotein ( HDL ) cholesterol levels .
However , there is evidence that adding testosterone to HT has a beneficial effect on sexual function in postmenopausal women .
There was a reduction in HDL cholesterol associated with the addition of testosterone to the HT regimens .
It is , therefore , difficult to estimate the effect of testosterone on sexual function in association with any individual hormone treatment regimen
BACKGROUND : The value of adding testosterone to hormone therapy ( HT ) for the management of peri- and postmenopausal women is controversial and has not been systematic ally review ed .
OBJECTIVES : To determine the benefits and risks of testosterone therapy for peri- and postmenopausal women taking hormone therapy .