Overall , intervention groups obtained higher 25(OH)D concentration than controls and there was obvious dose – response effect between intake dose and 25(OH)D concentration .
Baseline 25(OH)D concentration and age were significant indicators for 25(OH)D concentration .
Conclusions Regional- and age-specific recommended dosages of VitD supplements for population to achieve optimal 25(OH)D concentrations have been suggested
Background / Objectives Optimal doses of vitamin D ( VitD ) supplement in different population s are unclear .
We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [ 25(OH)D ] concentration , to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different population s .
Estimations of Dietary Vitamin D Requirements in Black and White Children
Background : The Institute of Medicine ( IOM ) dietary guidelines for vitamin D are based on limited pediatric data . Our objective was to estimate the dietary vitamin D requirements for maintaining serum 25-hydroxyvitamin D [ 25(OH)D ] concentrations at the various IOM-considered thresholds of vitamin D status ( 12 , 16 , and 20 ng/ml ) during fall and winter in children . Methods : Ninety-six healthy 8- to 14-y-old Pittsburgh-area black and white children enrolled in a r and omized , placebo-controlled trial of vitamin D3 1,000 IU daily for 6 mo with baseline and 2-mo follow-up assessment s completed during October through April were studied .  Vitamin D intake from diet and study supplement adjusted for adherence and serum 25(OH)D were measured . Results : The  vitamin D intakes needed to maintain serum 25(OH)D concentrations at 12 , 16 , and 20 ng/ml in 90 % of the children were 581 , 1,062 , and 1543 IU/day , respectively . The estimated  vitamin D intakes needed to maintain serum 25(OH)D concentrations at 20 ng/ml in 97.5 % of the children was 2,098 IU/day . Conclusion : Our data suggest that the current vitamin D recommended dietary allowance ( RDA ) ( 600 IU/day ) is insufficient to cover the skeletal health needs of at least 50 % of black and white children
Overall , intervention groups obtained higher 25(OH)D concentration than controls and there was obvious dose – response effect between intake dose and 25(OH)D concentration .
Baseline 25(OH)D concentration and age were significant indicators for 25(OH)D concentration .
Conclusions Regional- and age-specific recommended dosages of VitD supplements for population to achieve optimal 25(OH)D concentrations have been suggested
Background / Objectives Optimal doses of vitamin D ( VitD ) supplement in different population s are unclear .
We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [ 25(OH)D ] concentration , to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different population s .