Similar effects also appeared in SBP and DBP categories regardless of follow-up duration .
PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions .
In adults without IGT or diabetes , lifestyle interventions result ed in significant improvements in SBP , DBP , TC , LDL-C , HDL-C , and TG , and might further reduce CVD risk
Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease ( CVD ) risk among persons with impaired glucose tolerance ( IGT ) , but it is unclear whether they should be implemented among persons without IGT .
We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes .
The Women on the Move Through Activity and Nutrition (WOMAN) study: final 48-month results.
The Women on the Move through Activity and Nutrition ( WOMAN ) study was design ed to test whether a nonpharmacological intervention including qualitative and quantitative dietary changes to induce weight loss and increased physical activity levels would reduce blood triglyceride levels and number of low-density lipoprotein particles ( LDL-P ) . Such decreases in lipoproteins and other risk factors could reduce or slow progression of sub clinical cardiovascular disease ( CVD ) . Study participants were r and omized to either the intervention ( Lifestyle Change ) or assessment ( Health Education ) group . Most of the intervention ended at the 30-month visit . The last 48-month examination was completed in 9/2008 . There was very substantial weight loss and increased exercise during the first 30 months of the trial result ing in significant decreases in CV risk factors . Most of the intervention effect was lost through 48 months . Weight loss was 3.4 kg in Lifestyle Intervention and 0.2 kg in the Health Education at 48 months ( P = 0.000 ) . There were no significant changes at 48 months in lipid levels , blood pressure ( BP ) , glucose , insulin , or in the sub clinical measures of coronary calcium , carotid intima media thickness , or plaque . There was a significant decrease in long-distance corridor walk time in the Lifestyle vs. Health Education groups . Significant lifestyle changes can be achieved that result in decreases in CV risk factors . Whether such changes reduce CV outcomes is still untested in clinical trials of weight loss or exercise . Long-term maintenance of successful lifestyle changes , weight loss and reduced risk factors is the hurdle for lifestyle interventions attempting to prevent CV and other chronic diseases
Similar effects also appeared in SBP and DBP categories regardless of follow-up duration .
PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions .
In adults without IGT or diabetes , lifestyle interventions result ed in significant improvements in SBP , DBP , TC , LDL-C , HDL-C , and TG , and might further reduce CVD risk
Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease ( CVD ) risk among persons with impaired glucose tolerance ( IGT ) , but it is unclear whether they should be implemented among persons without IGT .
We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes .