There was no increased risk of infections with IV iron .
Gastrointestinal AEs were reduced with IV iron .
CONCLUSION Intravenous iron therapy is not associated with an increased risk of SAEs or infections .
Infusion reactions are more pronounced with IV iron
OBJECTIVE To amass all available evidence regarding the safety of intravenous ( IV ) iron preparations to provide a true balance of efficacy and safety .
Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy.
OBJECTIVE The incidence of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy is estimated to be more than 50 % . Transfusion has been the mainstay of hematologic support with its inherent hazards including infection and transfusion reaction . The aim of this study was to examine the impact of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients undergoing concurrent chemoradiotherapy . METHODS From Oct. 2003 to Dec. 2005 , 75 patients were treated with platinum-based concurrent chemoradiotherapy .  Thirty patients received 200 mg of iron sucrose intravenously ( study group ) and 45 patients did not receive it ( control group ) . RESULTS In the study group , only 12 ( 40.0 % ) patients required blood transfusions , whereas 29 ( 64.0 % ) patients in the control group needed blood transfusions ( P=0.04 ) . Mean transfusion units were 1.87 units in the study group and 3.58 units in the control group ( P=0.04 ) . CONCLUSION This study showed that intravenous supply of iron sucrose could decrease transfusion requirement and increase serum hemoglobin level in patients with cervical carcinoma undergoing concurrent chemoradiotherapy . Therefore , intravenously administered iron sucrose would be effective in the prevention of anemia of cervical cancer patients receiving concurrent chemoradiotherapy
There was no increased risk of infections with IV iron .
Gastrointestinal AEs were reduced with IV iron .
CONCLUSION Intravenous iron therapy is not associated with an increased risk of SAEs or infections .
Infusion reactions are more pronounced with IV iron
OBJECTIVE To amass all available evidence regarding the safety of intravenous ( IV ) iron preparations to provide a true balance of efficacy and safety .