Results show that various classes of antidepressants exert improving effects on cognitive function across several cognitive domains .
Specifically , studies suggest that SSRIs , the SSRE tianeptine , the SNRI duloxetine , vortioxetine and other antidepressants such as bupropion and moclobemide may exert certain improving effects on cognitive function in depression , such as in learning and memory and executive function .
The few non-pharmacological studies conducted employing cognitive orientated treatments and cognitive remediation therapy show promising results for the improvement of cognitive impairment in depression .
Cognitive dysfunction is of clinical significance and exerts longst and ing implication on patients ׳ function .
Pharmacological and non-pharmacological treatments of cognitive dysfunction are emerging .
This review evaluates pharmacological and non-pharmacological treatments of cognitive impairment primarily in the domains of memory , attention , processing speed and executive function in clinical depression .
Antidepressive therapy with escitalopram improves mood, cognitive symptoms, and identity memory for angry faces in elderly depressed patients.
Depression is a common disorder in the elderly h and icapping patients with affective and cognitive symptoms . Because of their good tolerability relative to the older tricyclic compounds , selective serotonin reuptake inhibitors ( SSRIs ) are increasingly used for the treatment of depression in the elderly . Little is known about their effects on cognition in elderly patients . In the present 4-wk , single-centre , r and omized , open-label trial we investigated the antidepressive effects of escitalopram , an SSRI , in 18 elderly depressed patients [ mean age ( + /-s.e.m . ) 76.2+/-1.8 yr ] compared to 22 healthy age-matched controls ( mean age 76.9+/-1.8 yr ) . Affective and cognitive symptoms were assessed using the Geriatric Depression Scale ( GDS ) , Mini-Mental State Examination ( MMSE ) , and a face portrait recognition test to assess memory for happy and angry faces .  Depressed patients prior to treatment had markedly reduced memory performance . Treatment with escitalopram improved affective and cognitive symptoms significantly . Furthermore , escitalopram treatment improved memory for negative facial stimuli .  Control subjects confirmed the well- established memory bias favouring recognition of identities acquired with happy expressions . Importantly , this bias was absent in depressed patients prior to , but also after treatment . In conclusion , escitalopram , even after a relatively short treatment period , was effective in treating  depression in the elderly and may help improve cognitive performance for social stimuli
Results show that various classes of antidepressants exert improving effects on cognitive function across several cognitive domains .
Specifically , studies suggest that SSRIs , the SSRE tianeptine , the SNRI duloxetine , vortioxetine and other antidepressants such as bupropion and moclobemide may exert certain improving effects on cognitive function in depression , such as in learning and memory and executive function .
The few non-pharmacological studies conducted employing cognitive orientated treatments and cognitive remediation therapy show promising results for the improvement of cognitive impairment in depression .
Cognitive dysfunction is of clinical significance and exerts longst and ing implication on patients ׳ function .
Pharmacological and non-pharmacological treatments of cognitive dysfunction are emerging .
This review evaluates pharmacological and non-pharmacological treatments of cognitive impairment primarily in the domains of memory , attention , processing speed and executive function in clinical depression .