Conclusion Our findings may encourage curcumin supplementation based on its meaningful effect on glycemic control and positive trend on lipid outcomes in prediabetes and T2DM
Scope Studies have demonstrated inconsistent effects of curcumin on glycemic outcomes and lipid parameters in patients with prediabetes and type 2 diabetes mellitus ( T2DM ) .
This study aim ed to assess the effect of curcumin on glycemic control and lipid profile in prediabetes and T2DM .
A single consumption of curry improved postprandial endothelial function in healthy male subjects: a randomized, controlled crossover trial
Background Curry , one of the most popular foods in Japan , contains spices that are rich in potentially antioxidative compounds , such as curcumin and eugenol . Oxidative stress is thought to impair endothelial function associated with atherosclerosis , a leading cause of cardiovascular events . The aim of this study was to determine whether a single consumption of curry meal would improve endothelial function in healthy men . Methods Fourteen healthy male subjects ( BMI 23.7 ± 2.7 kg/m2 ; age 45 ± 9 years ) were given a single serving of curry meal or spice-free control meal ( 180 g of curry or control and 200 g of cooked rice ; approximately 500 kcal in total ) in a r and omized , controlled crossover design . Before and 1 hr after the consumption , fasting and postpr and ial flow-mediated vasodilation ( FMD ) responses and other parameters were measured . Results The consumption of the control meal decreased FMD from 5.8 ± 2.4 % to 5.1 ± 2.3 % ( P = 0.039 ) . On the other h and , the consumption of the curry meal increased FMD from 5.2 ± 2.5 % to 6.6 ± 2.0 % ( P = 0.001 ) , and the postpr and ial FMD after the curry meal was higher than that after the control meal ( P = 0.002 ) . Presence of spices in the curry did not alter significantly the systemic and forearm hemodynamics , or any biochemical parameters including oxidative stress markers measured . Conclusions These findings suggest that the consumption of curry ameliorates postpr and ial endothelial function in healthy male subjects and may be beneficial for improving cardiovascular health . Trial registration UMIN Clinical Trials Registry 000012012
Conclusion Our findings may encourage curcumin supplementation based on its meaningful effect on glycemic control and positive trend on lipid outcomes in prediabetes and T2DM
Scope Studies have demonstrated inconsistent effects of curcumin on glycemic outcomes and lipid parameters in patients with prediabetes and type 2 diabetes mellitus ( T2DM ) .
This study aim ed to assess the effect of curcumin on glycemic control and lipid profile in prediabetes and T2DM .