Results Although highlighting a general lack of high- quality real-life effectiveness observational research on these clinical ly important topics , the analysis provided insights into how identified observational studies might inform asthma guidelines developers and clinicians .
Overall , RELEVANT appeared reliable and easy to use by expert review ers .
Conclusions Using such quality appraisal tools is m and atory to assess whether specific observational real-life effectiveness studies can be used to inform guideline development and /or decision-making in clinical practice
Abstract Introduction A Task Force was commissioned jointly by the European Academy of Allergy and Clinical Immunology ( EAACI ) and the Respiratory Effectiveness Group ( REG ) to develop a  quality assessment tool for real-life observational research to identify high- quality real-life asthma studies that could be considered within future guideline development .
Interventions to improve inhaler technique for people with asthma
This Cochrane review contains 29 r and omised controlled trials ( RCT ) involving 2210 participants ( range 21–201 ) ( Normansell et al. , 2017 ) . Included studies targeted adults and adolescents ( aged 12 years and over ) and children ( aged under 12 years ) with asthma . Follow-up ranged from 2 to 26 weeks . Participants with other respiratory comorbidities , including chronic obstructive pulmonary disease and bronchiectasis , were excluded . Studies examined interventions conducted in hospital , primary care , community or outpatient care setting s. These included interventions aim ed at  improving inhaler technique compared with usual care with no additional intervention , or with alternative interventions such as asthma education only or a different type/intensity of inhaler technique intervention . Twelve studies evaluated enhanced face-to-face training , nine used multimedia-delivered training and the rest used  technique feedback devices . Studies were conducted in Europe ( n= 11 , of which 6 were in UK and 1 each in Belgium , Denmark , France , Irel and and Italy ) , USA ( n= 7 ) , Australia ( n= 4 ) , Asia ( n= 3 ) , Africa ( n= 1 ) and 3 were of unknown origin . Interventions were delivered by trained health care professionals including nurses , respiratory or physiotherapists , pharmacists and physicians
Results Although highlighting a general lack of high- quality real-life effectiveness observational research on these clinical ly important topics , the analysis provided insights into how identified observational studies might inform asthma guidelines developers and clinicians .
Overall , RELEVANT appeared reliable and easy to use by expert review ers .
Conclusions Using such quality appraisal tools is m and atory to assess whether specific observational real-life effectiveness studies can be used to inform guideline development and /or decision-making in clinical practice
Abstract Introduction A Task Force was commissioned jointly by the European Academy of Allergy and Clinical Immunology ( EAACI ) and the Respiratory Effectiveness Group ( REG ) to develop a  quality assessment tool for real-life observational research to identify high- quality real-life asthma studies that could be considered within future guideline development .