We found no evidence to support a protective association between perinatal use of probiotics and doctor diagnosed asthma or childhood wheeze .
R and omised controlled trials to date have not yielded sufficient evidence to recommend probiotics for the primary prevention of these disorders .
OBJECTIVE To evaluate the association of probiotic supplementation during pregnancy or infancy with  childhood asthma and wheeze .
The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Flaws in the design , conduct , analysis , and reporting of r and omised trials can cause the effect of an intervention to be underestimated or overestimated . The Cochrane Collaboration ’s tool for assessing risk of bias aims to make the process clearer and more
We found no evidence to support a protective association between perinatal use of probiotics and doctor diagnosed asthma or childhood wheeze .
R and omised controlled trials to date have not yielded sufficient evidence to recommend probiotics for the primary prevention of these disorders .
OBJECTIVE To evaluate the association of probiotic supplementation during pregnancy or infancy with  childhood asthma and wheeze .