Commonly measured constructs of mobility included walking , climbing stairs , and lower extremity function .
There was heterogeneity in ways of defining and measuring mobility limitation in older adults living in the community .
Mobility is critical in maintaining independence in older adults .
This study aims to systematic ally review the scientific literature to identify measures of mobility limitation for community-dwelling older adults .
Homocysteine and mobility in older adults.
OBJECTIVES To determine the influence of homocysteine on  mobility decline in older adults . DESIGN Prospect i ve cohort . SETTING Einstein Aging Study , community-based aging study . PARTICIPANTS Five hundred seventy-four older adults without dementia ( mean age 80.2 + /- 5.4 , 61 % women ) . MEASUREMENTS Mobility decline defined using gait velocity measurements at baseline and annual follow-up visits . Linear mixed effects models were used to adjust for age , sex , education , and other potential confounders . RESULTS Higher homocysteine levels were associated with slower gait velocity at baseline . Adjusted for age , sex , and education , a one-unit increase in baseline log homocysteine levels was associated with a 2.95-cm/s faster mobility decline per year ( P=.01 ) over a median follow-up of 1.4 years . The 140 subjects in the highest quartile of homocysteine had a faster rate of mobility decline ( 1.75 cm/s per year faster , P=.01 ) than the 434 subjects in the lowest three quartiles of homocysteine ( < or=15 micromol/L ) . The association between homocysteine and mobility decline remained robust even after adjusting for multiple confounders and accounting for the presence of clinical gait abnormalities . CONCLUSION Higher homocysteine levels are associated with greater risk of mobility decline in community-residing older adults
Commonly measured constructs of mobility included walking , climbing stairs , and lower extremity function .
There was heterogeneity in ways of defining and measuring mobility limitation in older adults living in the community .
Mobility is critical in maintaining independence in older adults .
This study aims to systematic ally review the scientific literature to identify measures of mobility limitation for community-dwelling older adults .