Conclusion Applying the CHERG rules , we recommend a 73 % reduction in anemia at term with daily iron ( alone ) supplementation or iron/folate ( combined ) vs. no intervention or placebo ; for inclusion in the LiST model .
Introduction Iron deficiency is the most prevalent nutrient deficiency in the world , particularly during pregnancy .
According to the literature , anemia , particularly severe anemia , is associated with increased risk of maternal mortality .
It also puts mothers at risk of multiple perinatal complications .
Numerous studies in the past have evaluated the impact of supplementation with iron and iron-folate but data regarding the efficacy and quality of evidence of these interventions are lacking .
This article aims to address the impact of iron with and without folate supplementation on maternal anemia and provides outcome specific quality according to the Child Health Epidemiology Reference Group ( CHERG ) guidelines .
A randomised placebo-controlled trial to determine the effect of iron supplementation on pregnancy outcome in pregnant women with haemoglobin > or = 13.2 g/dl.
OBJECTIVE To study the effect of iron supplementation on pregnancy outcome in pregnant women with haemoglobin ( Hb ) > or = 13.2 g/dl . DESIGN A r and omised , double-blind , placebo-controlled trial . SETTING Routine health services . POPULATION Seven hundred and twenty-seven pregnant women with Hb > or = 13.2 g/dl in the early stage of the second trimester . METHODS Each woman took one ferrous sulphate [ DOSAGE ERROR CORRECTED ] tablet ( 150 g tablet , containing 50 mg of elemental iron ) [ DOSAGE ERROR CORRECTED ] daily in the case group ( n = 370 ) or placebo in the control group ( n = 357 ) throughout pregnancy . MAIN OUTCOME MEASURES Pregnancy outcome . RESULTS While there were no significant differences in demographic and obstetric characteristics between the two groups before any intervention , small-for-gestational-age birth rate and the number of women with hypertension disorder increased significantly in the case group in comparison with the control group ( 57 [ 15.7 % ] versus 36 [ 10.3 % ] , P = 0.035 , 10 [ 2.7 % ] versus 3 [ 8 % ] , P = 0.05 , respectively ) . CONCLUSIONS Our finding proves that routine iron supplementation in nonanaemic women is not rational and may be harmful
Conclusion Applying the CHERG rules , we recommend a 73 % reduction in anemia at term with daily iron ( alone ) supplementation or iron/folate ( combined ) vs. no intervention or placebo ; for inclusion in the LiST model .
Introduction Iron deficiency is the most prevalent nutrient deficiency in the world , particularly during pregnancy .
According to the literature , anemia , particularly severe anemia , is associated with increased risk of maternal mortality .
It also puts mothers at risk of multiple perinatal complications .
Numerous studies in the past have evaluated the impact of supplementation with iron and iron-folate but data regarding the efficacy and quality of evidence of these interventions are lacking .
This article aims to address the impact of iron with and without folate supplementation on maternal anemia and provides outcome specific quality according to the Child Health Epidemiology Reference Group ( CHERG ) guidelines .