In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .
The effect of zinc supplements on lipoproteins and copper status.
As part of a study to determine the effect of 150 mg zinc/day on plasma lipoproteins , healthy young female ( n = 26 ; mean age 27 years ) and male ( n = 21 ; mean age 28 years ) volunteers took part in a double-blind cross-over trial lasting 12 weeks . During 6 weeks of supplementation , plasma Zn rose significantly in both groups , indicating compliance . Plasma total cholesterol remained unchanged in both males and females . However , mean LDL-cholesterol decreased from 2.38 to 2.17 mmol/l in females and there was a trend for total HDL-cholesterol to be redistributed in that HDL2 rose and HDL3 fell slightly . In parallel with these changes in females , Zn supplements reduced the ferroxidase activity of serum caeruloplasmin ( from 13.0 to 11.3 U/ml ) and the antioxidant activity of erythrocyte superoxide dismutase ( E-SOD ) ( from 4557 to 3638 U/g Hb ) and CuZn E-SOD ( from 2184 to 1672 U/g Hb ) . Plasma Cu and haematocrit were unaffected . No such changes were seen in males in either lipoproteins or these indicators of Cu status . Since the females were lighter than the males but received the same dose , a dose-response effect rather than a sex difference can not be ruled out . Overall , Zn supplements significantly decrease a major risk factor for CHD in females but reduced their Cu status
In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .