No significant difference was found between other treatments .
Conclusion Compared with antimuscarinic drugs , PTENS was associated with significant better efficacy considering MVV , but more constipation events in de novo OAB children .
Antimuscarinic drugs showed remarkably better efficacy considering MVV and comparable safety profile compared with urotherapy .
Objective To compare these managements focusing on the efficacy and safety to treat overactive bladder ( OAB ) in children through network meta- analysis ( NMA ) .
Effects of transcutaneous neuromodulation (TENS) on overactive bladder symptoms in children: a randomized controlled trial.
BACKGROUND The aim of the present study was to investigate whether addition of transcutaneous electrical nerve stimulation ( TENS ) treatment improves the results of st and ard urotherapy in children with overactive bladder ( OAB ) symptoms . MATERIAL AND METHODS Sixty-two children with symptoms of OAB and incontinence were included . The children were r and omized either to st and ard urotherapy treatment alone or a combination of st and ard urotherapy and TENS . The effect variables were taken from a voiding-drinking diary : number of voiding , number of incontinence episodes , and maximum voided volume . RESULTS Both treatment groups had good treatment results , with no significant difference between the groups . In the st and ard treatment group 13/28 ( 46 % ) were completely dry and 11/28 ( 40 % ) had a decrease in incontinence episodes , compared to 16/24 ( 67 % ) and 3/24 ( 13 % ) , respectively , in the st and ard+TENS group ( p=0.303 ) . The number of voiding decreased in two-thirds of the patients in both groups . However , maximal voided volume only increased in the st and ard treatment group . Subjectively 72 % and 80 % considered themselves significantly improved or free of symptoms . Previous treatment was registered in 15/55 ( 27 % ) . All efficacy variables decreased in those with previous treatment , but with no difference between the st and ard and st and ard+TENS treatment groups . The only difference noted was when comparing the children without previous treatment in the groups : a significantly higher proportion were completely dry in the TENS group ( 12/18 [ 71 % ] versus 10/22 [ 48 % ] , p=0.05 ) . CONCLUSION Our results showed no significant difference overall in treatment response to OAB symptoms between urotherapy only and urotherapy+TENS , whereas a tendency to difference was found in children without previous treatment . Thus with good urotherapy support , TENS only seems to have marginal additional effects on OAB symptoms
No significant difference was found between other treatments .
Conclusion Compared with antimuscarinic drugs , PTENS was associated with significant better efficacy considering MVV , but more constipation events in de novo OAB children .
Antimuscarinic drugs showed remarkably better efficacy considering MVV and comparable safety profile compared with urotherapy .
Objective To compare these managements focusing on the efficacy and safety to treat overactive bladder ( OAB ) in children through network meta- analysis ( NMA ) .