In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .
Effects of selenium and zinc supplementation on nutritional status in patients with cancer of digestive tract†
Objective : To evaluate the effect of oral administration of selenium and zinc tablets in patients with cancer of the digestive tract during chemotherapy . Design : A case – control , r and omized study . Setting : Medical Oncology , II University of Naples , Naples , Italy . Subjects : A total of 60 patients ( median age 55 y , range 46–61 y ) with diagnosis of gut cancer were r and omized in 1999 . Patients were treated for 60 days with chemotherapy .  Interventions : Trace elements were measured by atomic absorption spectroscopy .  The nutritional status of the patients was assessed by biochemical and bio-impedance analysis ( BIA ) parameters in basal condition and after 60 days of treatment . Oral administration of selenium and zinc in oral tablet form for 50 days was Se 200 μg/day ( 50 μg/tablet ) and Zn 21 mg/day ( 7 mg/tablet ) . Results : Both in the basal condition and at 60 days all patients were malnourished . Selenium and zinc concentrations were significantly lower ( P<0.01 ) whereas copper concentration was significantly higher ( P<0.01 ) in cancer patients than in control subjects . However , 21/30 ( 70 % ) of those treated with Se and Zn did not showed a further worsening of nutritional status and experienced a significant decrease of asthenia with an increase of appetite . On the other h and , 24/30 ( 80 % ) untreated patients had a significant decline of all parameters studied after 60 days ( prealbumin , cholesterol , transferrin , P<0.05 vs 0 time ; total proteins , albumin/globulin ratio , P<0.01 vs 0 time ; fat-free mass , fat mass , Na+/K+ ratio , body mass index P<0.05 vs 0 time ; fat free mass/fat mass , total body water , extra cellular/intra cellular water , basal metabolic rate : P<0.01 vs 0 time ) . Conclusions : Data indicate that Se and Zn supplementation may improve the clinical course of general conditions in patients with gut cancer . These effects of Se and Zn require confirmation in an independent trial of appropriate design before new public health recommendations regarding Se and Zn supplementation can be made . European Journal of Clinical Nutrition ( 2001 ) 55 ,
In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .