In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .
The effect of zinc supplementation on plasma lipids and low-density lipoprotein oxidation in males.
Recent studies in animals and in vitro support the hypothesis that zinc , an essential micronutrient , possesses antioxidant properties . The aims of this study were to determine whether zinc provides antioxidant protection in humans by decreasing low-density lipoprotein ( LDL ) oxidizability and to determine the effect of zinc supplementation on plasma lipid and its distribution among lipoproteins . Ten healthy male volunteers were recruited to participate in a r and omized crossover trial . Subjects were asked to consume 50 mg zinc as 220 mg zinc sulphate ( equivalent to 4 x recommended dietary intake , or RDI ) daily for 4 weeks , followed by placebo , and vice versa . Venous blood sample s were collected at 2-week intervals for the determination of plasma lipids and the in vitro oxidizability of LDL in the presence of copper ions . No changes in the oxidizability of LDL or the plasma concentrations of total cholesterol , high-density lipoprotein ( HDL ) cholesterol and its subfractions , LDL cholesterol , or triacylglycerol were observed following zinc supplementation compared to placebo .  Plasma zinc concentrations were increased significantly , indicating that the lack of effect was not due to poor compliance . The antioxidant effect of  zinc  in relation to LDL was not demonstrated in humans at this dose , and higher doses are unlikely to be effective given the adverse interaction with copper metabolism and the potential decrease in the activity of superoxide dismutase , a free radical quenching enzyme . The findings of this study suggest that zinc provides little , if any , antioxidant protection against LDL oxidation in humans
In conclusion , Zinc supplementation  has favourable effects on plasma lipid parameters .
Zinc supplementation  significantly reduced total cholesterol , LDL cholesterol and triglycerides .
Therefore it may have the potential to reduce the incidence of atherosclerosis related morbidity and mortality
Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism .
It may also have a protective role in the prevention of atherogenesis .
Numerous studies have evaluated the effects of Zinc supplementation on serum lipids in humans and have demonstrated varying results .
We systematic ally evaluated the literature and performed a meta- analysis on the effects of Zinc supplementation on serum lipids .