Serious adverse events attributable to vitamin D supplementation were rare across all studies .
On the basis of studies review ed to date , the strongest evidence supports further research into adjunctive vitamin D therapy for tuberculosis , influenza , and viral upper respiratory tract illnesses .
OBJECTIVE To review the existing human controlled intervention studies of vitamin D as adjunctive therapy in setting s of infection and provide recommendations for design and implementation of future studies in this field on the basis of the evidence review ed .
Hepatitis B vaccines in patients with chronic renal failure before dialysis.
Hepatitis B remains a significant risk to patients receiving chronic hemodialysis , but no certain method of prevention has been identified . We tested two vaccines , plasma-derived vaccine ( 40-micrograms dose ) and recombinant-derived vaccine ( 40-micrograms and 20-micrograms doses ) , in 61 patients with chronic renal failure who were not yet dependent on dialysis . Patients were followed up clinical ly and with laboratory tests of kidney function and hepatitis B virus serology for one year . Significantly more recipients of plasma-derived vaccine responded to vaccination ; they also achieved a higher titer of antibody to hepatitis B virus than did recipients of recombinant-derived vaccine when evaluated at 6 , 7 , 9 , and 12 mo after vaccination . No serious side effects were observed with any vaccine preparation , nor were excessive adverse effects observed in any group . Compared with the dialysis patients previously studied , patients with renal failure who were not yet dependent on dialysis responded more favorably to the hepatitis B virus vaccine
Serious adverse events attributable to vitamin D supplementation were rare across all studies .
On the basis of studies review ed to date , the strongest evidence supports further research into adjunctive vitamin D therapy for tuberculosis , influenza , and viral upper respiratory tract illnesses .
OBJECTIVE To review the existing human controlled intervention studies of vitamin D as adjunctive therapy in setting s of infection and provide recommendations for design and implementation of future studies in this field on the basis of the evidence review ed .