Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .
A randomized controlled trial comparing effects of a low-energy diet with n-3 polyunsaturated fatty acid supplementation in patients with non-alcoholic fatty liver disease
Background : Weight loss is the cornerstone of NAFLD management , but weight maintenance is difficult . Some studies have suggested that n-3 polyunsaturated fatty acid ( n-3 PUFA ) might have beneficial effects in NAFLD . We aim to compare the effects of a low-energy diet with n-3 PUFA supplementation on liver enzymes , body composition , and cardiometabolic risk factors in NAFLD . Material s and Methods : The study was a r and omized controlled trial conducted in Urmia in Iran from October 2016 to May 2017 . One hundred and fourteen eligible patients were r and omly assigned to one of the three following groups : low-energy diet group , n-3 PUFA supplementation ( fish oil ) group ( 1500 mg/d ) , or control group for 12 weeks . Liver enzymes , lipid profile , insulin resistance , and body composition were assessed before and after the intervention . Results : One hundred and four patients completed the study . All groups lost weight , but the reductions were greater in the diet group ( −2.97 ± 2.79 kg , P = 0.001 ) . The diet group had significant decreases in fat mass compared to other groups . Insulin resistance , total cholesterol , and low-density lipoprotein cholesterol significantly decreased only in the diet group , and patients who lost weight ≥4 % showed significantly larger decreases in serum liver enzymes . N-3 PUFA had no beneficial effects on the study outcomes . Conclusion : We found that 1500 mg/d n-3 PUFA supplied for 12 weeks , in contrast to 3.40 ± 2.98 % weight loss , does not improve liver enzymes , body composition , and cardiometabolic risk factors in NAFLD patients
Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .