After the intervention , Hb concentration and serum ferritin concentration were both higher in the NaFeEDTA group compared with the control group .
Subgroup analysis indicated that a lower baseline Hb level was associated with a greater increase in Hb concentration .
No significant difference in serum Zn concentration was found .
We concluded that NaFeEDTA increased both Hb concentration and serum ferritin concentration substantially in Fe-deficient population s , and could be an effective Fe preparation to combat Fe deficiency
Fortification of sugar with iron sodium ethylenediaminotetraacetate (FeNaEDTA) improves iron status in semirural Guatemalan populations.
A 32-mo-long , double-blind field study involving one highl and control community receiving only vitamin A-fortified sugar and three vitamin A- and FeNaEDTA-sugar-fortified communities , two in the lowl and s and one in the highl and s of Guatemala , was undertaken to test the effectiveness of this approach in controlling iron deficiency .  The communities ' population ranged between 1200 and 17000 .  Sugar fortified with 1 g FeNaEDTA and 15 mg retinol as retinyl palmitate/kg was stable , did not segregate , and was well accepted by the communities . The impact of fortification on iron nutrition was estimated at 8 , 20 , and 32 mo of intervention . All pregnant women and subjects with severe anemia received supplements or treatment and were excluded from the analysis . Iron stores in the fortified communities increased significantly except for women 18 - 48 y of age in one lowl and community and > 49 y in the highl and community . Iron stores in the control community remained unchanged except for a rise among adult males
After the intervention , Hb concentration and serum ferritin concentration were both higher in the NaFeEDTA group compared with the control group .
Subgroup analysis indicated that a lower baseline Hb level was associated with a greater increase in Hb concentration .
No significant difference in serum Zn concentration was found .
We concluded that NaFeEDTA increased both Hb concentration and serum ferritin concentration substantially in Fe-deficient population s , and could be an effective Fe preparation to combat Fe deficiency