INTERPRETATION There was a clinical ly relevant association between early migration of TKPs and late revision for loosening .
PURPOSE We performed two parallel systematic review s and meta-analyses to determine the association between early migration of tibial components and late aseptic revision .
Inferior performance of Boneloc bone cement in total knee arthroplasty: a prospective randomized study comparing Boneloc with Palacos using radiostereometry (RSA) in 19 patients.
We compared Boneloc bone cement with conventional cement ( Palacos ) in fixating the tibial component during 2 - 5 years in 19 patients with gonarthrosis undergoing total knee arthroplasty in a prospect i ve r and omized study .  Boneloc displayed significantly larger migration , subsidence and lift-off than Palacos . The difference was identifiable already within 3 months postoperatively , but became significant at 12 months . In the Boneloc group , all components showed subsidence of the posterior part and lift-off of the anterior part of the tibial component , whereas in the Palacos group , the locations of subsidence and lift-off were evenly distributed about the edge of the implant . At 5 years , both Boneloc knees so far investigated were clinical failures with high migration rates . We conclude that , even in total knee arthroplasty , there is a substantial risk that Boneloc leads to inferior clinical results , but later than in hip replacements
INTERPRETATION There was a clinical ly relevant association between early migration of TKPs and late revision for loosening .
PURPOSE We performed two parallel systematic review s and meta-analyses to determine the association between early migration of tibial components and late aseptic revision .