Only antibiotic-impregnated suture , a no-shave policy , and double gloving with glove change prior to shunt h and ling , were associated with a significant reduction in shunt infection .
In a hospital with high methicillin-resistant staphylococcus aureus ( MRSA ) prevalence , a r and omized controlled trial found that perioperative vancomycin rather than cefazolin significantly reduced shunt infection rates .
Conclusion Despite wide variation in compliance rates , the implementation of comprehensive surgical protocol s reduced shunt infection in all published studies .
Antibiotic-impregnated suture , a no-shave policy , double gloving with glove change prior to device manipulation , and 5 % chlorhexidine hair wash were associated with significant reductions in shunt infection
Purpose Cerebrospinal fluid shunt infection is associated with patient morbidity and high cost .
We conducted a systematic review of the current evidence of comprehensive surgical protocol s or individual interventions design ed to reduce shunt infection incidence .
A randomized trial of ceftriaxone versus trimethoprim-sulfamethoxazole to prevent ventriculoperitoneal shunt infection.
BACKGROUND AND PURPOSE Shunt infection represents a particularly morbid condition , which can also result in mortality . In order to decrease the high morbidity and mortality rates , prevention is an essential step . The purpose of this study was to compare the prophylactic use of ceftriaxone and trimethoprim-sulfamethoxazole ( SXT ) for the prevention of ventriculoperitoneal ( VP ) shunt infection . METHODS In this prospect i ve , single-institution , r and omized clinical trial , 107 children with hydrocephalus and an indication for shunting were r and omly assigned to prophylaxis with ceftriaxone ( n = 50 ) or SXT ( 55 ) , each administered as a single dose during anesthesia and two divided doses postoperatively . Patients were followed up for at least one year . RESULTS The mean age of patients was 15 months , and 85 % were aged 6 months or younger . During the first postoperative year , meningitis occurred in 13.5 % of patients receiving ceftriaxone and 14.5 % of the SXT group , with no statistically significant difference between the groups . Younger age , presence of cerebrospinal fluid leakage and aqueductal stenosis as a cause of hydrocephalus showed significant correlation with meningitis occurrence on univariate analysis . However , only the latter 2 factors were associated with meningitis on multivariate analysis . The risk of shunt infection did not correlate with the gender of the patient , time of VP shunt surgery , or duration of hospitalization for shunting . CONCLUSION Ceftriaxone and SXT showed similar efficacy in preventing shunt infection . Cerebrospinal fluid leakage before or after VP shunt placement and aqueductal stenosis were independent risk factors for meningitis after VP shunt
Only antibiotic-impregnated suture , a no-shave policy , and double gloving with glove change prior to shunt h and ling , were associated with a significant reduction in shunt infection .
In a hospital with high methicillin-resistant staphylococcus aureus ( MRSA ) prevalence , a r and omized controlled trial found that perioperative vancomycin rather than cefazolin significantly reduced shunt infection rates .
Conclusion Despite wide variation in compliance rates , the implementation of comprehensive surgical protocol s reduced shunt infection in all published studies .
Antibiotic-impregnated suture , a no-shave policy , double gloving with glove change prior to device manipulation , and 5 % chlorhexidine hair wash were associated with significant reductions in shunt infection
Purpose Cerebrospinal fluid shunt infection is associated with patient morbidity and high cost .
We conducted a systematic review of the current evidence of comprehensive surgical protocol s or individual interventions design ed to reduce shunt infection incidence .