Conclusion Neither HIIT nor MICT is superior for altering TC , TRG , or LDL-C , or TC-HDL-C ratio .
To raise HDL-C , HIIT may result in a larger effect size compared with MICT .
Objective To compare the effects of moderate intensity continuous training ( MICT ) and high intensity interval training ( HIIT ) on  adult lipid profiles ;  to identify training or participant characteristics that may determine exercise-induced change in total cholesterol ( TC ) , triglycerides ( TRG ) , high-density lipoprotein cholesterol ( HDL-C ) and low-density lipoprotein cholesterol ( LDL-C ) .
Energy-matched moderate and high intensity exercise training improves nonalcoholic fatty liver disease risk independent of changes in body mass or abdominal adiposity - A randomized trial.
BACKGROUND AND PURPOSE Exercise training is commonly prescribed for individuals diagnosed with nonalcoholic fatty liver disease ( NAFLD ) ; however , consensus regarding the volume and intensity of exercise for optimal benefits is lacking . Thus , we determined whether high intensity interval exercise training ( HIIT ) produced greater reductions in intrahepatic lipid ( IHL ) content and NAFLD risk factors compared with energy-matched moderate intensity continuous exercise training ( MICT ) in obese adults with liver steatosis . METHODS Eighteen obese adults were r and omized to either 4weeks of HIIT ( 4min 80 % VO2peak/3min , 50 % VO2peak ) or MICT ( 55 % VO2peak , ~60min ) , matched for energy expenditure ( ~400kcal/session ) and compared to five non-exercising age-matched control subjects .  IHL was measured by 1H-MRS and frequent blood sample s were analyzed for glucose , insulin , c-peptide , and NEFA levels during a liquid meal test ( 180min ) to characterize metabolic phenotype . RESULTS Baseline body weight , visceral abdominal adiposity , and fasting insulin concentrations were greater in the MICT vs HIIT group ( P<0.05 ) , while IHL was tightly matched between MICT and HIIT subjects ( P>0.05 ) , albeit higher than control subjects ( P<0.01 ) . Visceral abdominal adiposity , body mass , liver aminotransferases ( ALT , AST ) , and hepatic apoptotic/inflammatory markers ( cytokeratin 18 and fetuin a ) were not reduced with either exercise training intervention ( P>0.05 ) . Both HIIT and MICT lowered IHL ( HIIT , -37.0±12.4 % ; MICT , -20.1±6.6 % , P<0.05 ) ; however , the reduction in IHL was not statistically different between exercise intensities ( P=0.25 ) . Furthermore , exercise training decreased postpr and ial insulin , c-peptide , and lipid peroxidation levels ( iAUC , P<0.05 ) . CONCLUSIONS Collectively , these findings indicate that energy-matched high intensity and moderate intensity exercise are effective at decreasing IHL and NAFLD risk that is not contingent upon reductions in abdominal adiposity or body mass
Conclusion Neither HIIT nor MICT is superior for altering TC , TRG , or LDL-C , or TC-HDL-C ratio .
To raise HDL-C , HIIT may result in a larger effect size compared with MICT .
Objective To compare the effects of moderate intensity continuous training ( MICT ) and high intensity interval training ( HIIT ) on  adult lipid profiles ;  to identify training or participant characteristics that may determine exercise-induced change in total cholesterol ( TC ) , triglycerides ( TRG ) , high-density lipoprotein cholesterol ( HDL-C ) and low-density lipoprotein cholesterol ( LDL-C ) .