Available studies show convincingly the health benefits of lifestyle changes in CAD patients .
Effect estimates of combined dietary changes look promising .
BACKGROUND Guidelines for lifestyle and dietary modification in patients with coronary artery disease ( CAD ) are mainly supported by evidence from general population studies .
CAD patients , however , differ from the general population in age ( older ) and treatment with preventive drugs .
This review seeks to provide evidence for a prognostic benefit of lifestyle and dietary recommendations from studies in CAD patients .
Randomised controlled trial of cardioprotective diet in patients with recent acute myocardial infarction: results of one year follow up.
OBJECTIVE --To test whether a fat reduced diet rich in soluble dietary fibre , antioxidant vitamins , and minerals reduces complications and mortality after acute myocardial infa rct ion . DESIGN --R and omised , single blind , controlled trial . SETTING -- Primary and secondary care research centre for patients with myocardial infa rct ion . SUBJECTS--505 patients with suspected acute myocardial infa rct ion . Those with definite or possible acute myocardial infa rct ion and unstable angina based on World Health Organisation criteria were assigned to diet A ( n = 204 ) or diet B ( n = 202 ) within 24 - 48 hours of infa rct ion . INTERVENTIONS --Both groups were advised to follow a fat reduced diet . Group A was also advised to eat more fruit , vegetables , nuts , and grain products . MAIN OUTCOME MEASURES --Mortality from cardiac disease and other causes . Serum lipid concentrations and compliance with diet . RESULTS --Blood lipoprotein concentrations and body weight fell significantly in patients in group A compared with those in group B ( cholesterol fell by 0.74 mmol/l in group A v 0.32 mmol/l in group B , 95 % confidence interval of difference 0.14 to 0.70 , and weight by 7.1 v 3.0 kg , 0.52 to 7.68 ) . The incidence of cardiac events was significantly lower in group A than group B ( 50 v 82 patients , p less than 0.001 ) . Group A also had lower total mortality ( 21 v 38 died , p less than 0.01 ) than group B. CONCLUSIONS --Comprehensive dietary changes in conjunction with weight loss immediately after acute myocardial infa rct ion may modulate blood lipoproteins and significantly reduce complications and mortality after one year
Available studies show convincingly the health benefits of lifestyle changes in CAD patients .
Effect estimates of combined dietary changes look promising .
BACKGROUND Guidelines for lifestyle and dietary modification in patients with coronary artery disease ( CAD ) are mainly supported by evidence from general population studies .
CAD patients , however , differ from the general population in age ( older ) and treatment with preventive drugs .
This review seeks to provide evidence for a prognostic benefit of lifestyle and dietary recommendations from studies in CAD patients .