Conclusions RYGB surgery reverses the dyslipidaemia of obesity .
These findings support the use of RYGB in the management of high cardiovascular risk lipid profiles in morbid obesity
Background Obesity-related dyslipidaemia comprises hypercholesterolaemia , hypertriglyceridaemia , low HDL-cholesterol and normal to raised LDL-cholesterol levels .
40 % of morbidly obese surgical patients have dyslipidaemia .
Roux-en-Y gastric bypass ( RYGB ) surgery has many beneficial metabolic effects , but the full impact on plasma lipids has not been clearly defined .
Body Composition, Dietary Intake, and Energy Expenditure After Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Vertical Banded Gastroplasty: A Randomized Clinical Trial
Objective : To assess body composition , eating pattern , and basal metabolic rate in patients undergoing obesity surgery in a r and omized trial . Introduction : There is limited knowledge regarding how different bariatric surgical techniques function in terms of altering body composition , dietary intake , and basic metabolic rate . Methods : Non-superobese patients were r and omized to laparoscopic Roux-en-Y gastric bypass ( LGBP , n = 37 ) or laparoscopic vertical b and ed gastroplasty ( LVBG , n = 46 ) . Anthropometry , dual-energy x-ray absorptiometry ( DEXA ) , computed tomography ( CT ) , indirect calorimetry , and reported dietary intake were registered prior to and 1 year after surgery . Results : Follow-up rate was 97.6 % . LGBP patients had significantly greater reduction of waist circumference and sagittal diameter compared with LVBG . DEXA demonstrated a larger reduction of body fat in all compartments after LGBP , especially at the trunk ( P<0.001 ) . CT demonstrated more reduction of the visceral fat ( P=0.016 ) . Patients were able to eat all types of food after LGBP , although about 30 % cl aim ed they avoided fats . LGBP patients decreased their proportion of dietary fat significantly more than those operated on with LVBG ( P = 0.005 ) , who consumed more sweet foods and avoided whole meat and vegetables . Lean tissue mass ( LTM ) was proportionally less reduced , especially in men , after LGBP . The decreases in BMR postoperatively reflected the lower body mass in a pattern that did not differ among the groups . Conclusion : LGBP patients demonstrated better outcomes compared with LVBG patients in terms of body composition . Energy expenditure developed as expected postoperatively . A “ steering ” away from fatty foods after LGBP may be an important mechanism of action in gastric bypass
Conclusions RYGB surgery reverses the dyslipidaemia of obesity .
These findings support the use of RYGB in the management of high cardiovascular risk lipid profiles in morbid obesity
Background Obesity-related dyslipidaemia comprises hypercholesterolaemia , hypertriglyceridaemia , low HDL-cholesterol and normal to raised LDL-cholesterol levels .
40 % of morbidly obese surgical patients have dyslipidaemia .
Roux-en-Y gastric bypass ( RYGB ) surgery has many beneficial metabolic effects , but the full impact on plasma lipids has not been clearly defined .