RESULTS No statistical significant difference in bond strength between both categories was observed in caries-affected dentin at immediate evaluation and in sound dentin after ageing .
Etch- and -rinse adhesives , however , performed better in sound enamel and dentin substrates considering immediate bond strength .
None study assessed the long-term adhesive effectiveness to sound or demineralized enamel .
Although the articles included in this meta- analysis showed high heterogeneity and high risk of bias , the in vitro literature suggests superior performance of etch- and -rinse adhesives in primary teeth in comparison with self-etch systems
AIM To systematic ally review the literature for in vitro studies that evaluated the immediate or after ageing bond strength of  etch- and -rinse and self-etch adhesive systems to enamel and dentin of primary teeth .
Does the method of caries induction influence the bond strength to dentin of primary teeth?
PURPOSE To evaluate the effect of chemical and microbiological methods of caries induction on microtensile bond strength ( μTBS ) of current adhesive systems to primary dentin . MATERIAL S AND METHODS Flat dentin surfaces from 36 primary molars were assigned to 3 groups according to the method of inducing caries-affected dentin : ( 1 )  control ( sound dentin ) ; ( 2 )  pH cycling ; and ( 3 ) microbiological . In both methods , teeth were su bmi tted to caries induction for 14 days , and the sound dentin was stored in distilled water for the same period . Specimens were then r and omly reassigned according to adhesive system : a two-step etch- and -rinse adhesive ( Adper Single Bond 2 ) or a two-step self-etching system ( Clearfil SE Bond ) . Composite buildups were constructed and the teeth were sectioned to obtain bonded sticks ( 0.8 mm2 ) to be tested for microtensile bond strength . The μTBS means were analyzed by two-way ANOVA and Tukey 's tests ( α = 0.05 ) . Failure mode was evaluated using a stereomicroscope ( 400X ) . RESULTS Both methods of caries induction result ed in lower μTBS values ( with no significant difference between them ) than those obtained for sound dentin . Adhesive systems showed similar bond strength values . The percentage of premature failure was higher in the microbiological group , regardless of adhesive system . CONCLUSION Microbiological and pH-cycling methods are both suitable for simulating caries-affected dentin for bonding evaluations in primary teeth
RESULTS No statistical significant difference in bond strength between both categories was observed in caries-affected dentin at immediate evaluation and in sound dentin after ageing .
Etch- and -rinse adhesives , however , performed better in sound enamel and dentin substrates considering immediate bond strength .
None study assessed the long-term adhesive effectiveness to sound or demineralized enamel .
Although the articles included in this meta- analysis showed high heterogeneity and high risk of bias , the in vitro literature suggests superior performance of etch- and -rinse adhesives in primary teeth in comparison with self-etch systems
AIM To systematic ally review the literature for in vitro studies that evaluated the immediate or after ageing bond strength of  etch- and -rinse and self-etch adhesive systems to enamel and dentin of primary teeth .