This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
The Efficacy and Safety of a High Dose of Vitamin D in Mothers with Gestational Diabetes Mellitus: A Randomized Controlled Clinical Trial
Background : During pregnancy and lactation outst and ing changes occur in mother ’s vitamin D metabolism . This study was carried out to evaluate the efficacy of 300,000 IU vitamin D given intramuscularly on body status in new cases of gestational diabetes mellitus ( GDM ) . Methods : This is a r and omized clinical trial with the follow-up period of 3 months . Totally 45 participants were r and omly divided into intervention  group ( IG ) and control group ( CG ) . The IG received an IM injection of 300,000 IU of vitamin D , whereas CG did not . The glycosylated hemoglobin A1C ( HBA1C ) , serum 25-OH-D , parathyroid hormone ( PTH ) , serum calcium and phosphorus were measured . Results : Forty five patients including 24 with the mean age of 30.7±6.2 years in the IG and 21 with the mean age of 29.5±4.0 years in the CG participated in the study .  The median concentration of serum 25(OH)D3 in the IG was to 62.10 nmol/l after the intervention , showing an increase of around 158 % , compared to before intervention ( 24.25 nmol/l ) whereas the CG showed a decrease of around 4.5 % . Of the patients , 79.2 % of IG and 81.9 % of CG suffered to some degree from vitamin D deficiency . These figures were 4.2 % and 71.4 % for the IG and CG , respectively after the intervention . For the IG , the PTH was significantly lower and Ca was significantly higher after the intervention . The serum Phosphorus before and after the intervention in each group or between the two groups was not significant . Conclusions : The single 300,000 IM dose of vitamin D is regarded as an effective and safe to promptly improve vitamin D status in GDM . Trial Registration Number : I RCT
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .