Cognitive behavioral therapy may reduce relapse risk for adults with AN after weight restoration , although its efficacy in the underweight state remains unknown .
Variants of family therapy are efficacious in adolescents , but not in adults .
Evidence for AN treatment is weak ; evidence for treatment-related harms and factors associated with efficacy of treatment are weak ; and evidence for differential outcome by sociodemographic factors is nonexistent .
OBJECTIVE The RTI International-University of North Carolina at Chapel Hill Evidence -based Practice Center ( RTI-UNC EPC ) systematic ally review ed evidence on efficacy of treatment for anorexia nervosa ( AN ) , harms associated with treatments , factors associated with treatment efficacy , and differential outcome by sociodemographic characteristics .
Efficacy of citalopram in anorexia nervosa: a pilot study
INTRODUCTION Anorexia nervosa ( AN ) still lacks a defined treatment . Since fluoxetine proved effective in weight-restored anorexics , this pilot study evaluates the efficacy of another SSRI , citalopram , in restricting-type AN . EXPERIMENTAL PROCEDURES Fifty-two female anorectic out patients were r and omized in the citalopram ( n=26 ) and waiting list ( n=26 ) as a control group .  Efficacy was assessed using Eating Disorder Inventory-2 , Eating Disorder Inventory-Symptom Checklist , State-Trait Anger Expression Inventory , Beck Depression Inventory , Symptom Checklist-90 and Structured Clinical Interview for DSM-IV Axis II Disorders . RESULTS Thirteen patients dropped-out , thus 19 patients received citalopram and 20 remained in the control group . After 3 months of treatment , the citalopram group showed a decrease on BDI and SCL-90 Depression subscale and an improvement of baseline obsessive compulsive features on SCL-90 , EDI-2 impulsiveness and Trait-anger on STAXI . Weight gain was similar in the two groups . DISCUSSION These preliminary results support the efficacy of citalopram in anorectics . Citalopram seems to improve depression , obsessive-compulsive symptoms , impulsiveness and Trait-anger
Cognitive behavioral therapy may reduce relapse risk for adults with AN after weight restoration , although its efficacy in the underweight state remains unknown .
Variants of family therapy are efficacious in adolescents , but not in adults .
Evidence for AN treatment is weak ; evidence for treatment-related harms and factors associated with efficacy of treatment are weak ; and evidence for differential outcome by sociodemographic factors is nonexistent .
OBJECTIVE The RTI International-University of North Carolina at Chapel Hill Evidence -based Practice Center ( RTI-UNC EPC ) systematic ally review ed evidence on efficacy of treatment for anorexia nervosa ( AN ) , harms associated with treatments , factors associated with treatment efficacy , and differential outcome by sociodemographic characteristics .