By further separating studies into unisensory and multisensory ( bimodal : audiovisual ) ones , subgroup analysis indicated heterogeneous and unstable effects for unisensory temporal binding in the ASD group , but a more consistent and severe impairment in multisensory temporal integration represented by an enlarged temporal binding window in both clinical groups .
Such multisensory dysfunction is associated with symptoms like hallucinations and impaired social communications .
HighlightsMultisensory temporal dysfunction represented by an extended temporal binding window is a common feature of ASD and SSD.Unisensory temporal acuity is impaired in schizophrenia but may be spared in ASD.Multisensory dysfunction is associated with incoherent perception and communicative deficit that characterize SSD and ASD . &
NA ; Multisensory temporal integration could be compromised in both autism spectrum disorders ( ASD ) and schizophrenia spectrum disorders ( SSD ) and may play an important role in perceptual and cognitive impairment in these two disorders .
This review aim ed to quantitatively compare the sensory temporal acuity between healthy controls and the two clinical groups ( ASD and SSD ) .
Autistic traits in the general population: a twin study.
BACKGROUND Recent research has indicated that autism is not a discrete disorder and that family members of autistic prob and s have an increased likelihood of exhibiting autistic symptoms with a wide range of severity , often below the threshold for a diagnosis of an autism spectrum disorder . OBJECTIVE To examine the distribution and genetic structure of autistic traits in the general population using a newly established quantitative measure of autistic traits , the Social Responsiveness Scale ( formerly known as the Social Reciprocity Scale ) . METHODS The sample consisted of 788 pairs of twins aged 7 to 15 years , r and omly selected from the pool of participants in a large epidemiologic study ( the Missouri Twin Study ) . One parent of each pair of twins completed the  Social Responsiveness Scale on each child . The data were subjected to structural equation modeling . RESULTS Autistic traits as measured by the Social Responsiveness Scale were continuously distributed and moderately to highly heritable . Levels of severity of autistic traits at or above the previously published mean for patients with pervasive developmental disorder not otherwise specified were found in 1.4 % of boys and 0.3 % of girls . Structural equation modeling revealed no evidence for the existence of sex-specific genetic influences , and suggested specific mechanisms by which females may be relatively protected from vulnerability to autistic traits . CONCLUSIONS These data indicate that the social deficits characteristic of autism spectrum disorders are common . Given the continuous distribution of these traits , it may be arbitrary where cutoffs are made between research design ations of being " affected " vs " unaffected " with a pervasive developmental disorder . The genes influencing autistic traits appear to be the same for boys and girls . Lower prevalence ( and severity ) of autistic traits in girls may be the result of increased sensitivity to early environmental influences that operate to promote social competency
By further separating studies into unisensory and multisensory ( bimodal : audiovisual ) ones , subgroup analysis indicated heterogeneous and unstable effects for unisensory temporal binding in the ASD group , but a more consistent and severe impairment in multisensory temporal integration represented by an enlarged temporal binding window in both clinical groups .
Such multisensory dysfunction is associated with symptoms like hallucinations and impaired social communications .
HighlightsMultisensory temporal dysfunction represented by an extended temporal binding window is a common feature of ASD and SSD.Unisensory temporal acuity is impaired in schizophrenia but may be spared in ASD.Multisensory dysfunction is associated with incoherent perception and communicative deficit that characterize SSD and ASD . &
NA ; Multisensory temporal integration could be compromised in both autism spectrum disorders ( ASD ) and schizophrenia spectrum disorders ( SSD ) and may play an important role in perceptual and cognitive impairment in these two disorders .
This review aim ed to quantitatively compare the sensory temporal acuity between healthy controls and the two clinical groups ( ASD and SSD ) .