Best- evidence synthesis demonstrated a conflicting level of evidence for associations between the use of-amphetamine-type substances and the risk of sustaining an injury , and a moderate level of evidence between amphetamine use and the risk of death due to road trauma .
This is the first review to synthesis e evidence regarding the association between amphetamine-type substance use and the risk of injury or death due to a road traffic accident .
More conclusive evidence of death due to road trauma among amphetamine users may reflect significant and global deficits in functioning associated with effective vehicular control under the influence of this substance .
Amphetamine-type substances are frequently detected among drivers injured or killed due to road-trauma .
However , the role of this substance in crash causation remains equivocal .
We performed a systematic review to evaluate existing evidence regarding the association between amphetamine use and the risk of injury or death due to road traffic accidents .
Examining the effect of dl-3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine on the Standardized Field Sobriety Tests.
dl-3,4-methylenedioxymethamphetamine ( MDMA ) and methamphetamine are commonly used illicit drugs that are thought to impair driving ability . The St and ardized Field Sobriety Tests ( SFSTs ) are utilized widely to detect impairment associated with drugs other than alcohol in drivers , although limited evidence concerning MDMA and methamphetamine consumption on SFST performance exists . The aim of this study was to evaluate whether the SFSTs were a sensitive measure for identifying the presence of the specific isomer d-methamphetamine and MDMA . In a double-blind , within-subject , counter-balanced and placebo-controlled study , 58 healthy and abstinent recreational drugs users were administered three treatments : 100 mg of MDMA , 0.42 mg/kg d-methamphetamine , and placebo . For each condition the SFSTs were administered at 4 and 25 h post treatment . d-methamphetamine was not found to significantly impair SFST performance unlike MDMA , which significantly impaired SFST performance in comparison to placebo with 22 % of the sample failing the test at the 4h testing time-point . No differences were observed at the 25 h testing time-point for any of the conditions . It was concluded that the SFSTs are not efficient in identifying the presence of low level d-methamphetamine , and are significantly better at detecting the presence of MDMA at the levels assessed
Best- evidence synthesis demonstrated a conflicting level of evidence for associations between the use of-amphetamine-type substances and the risk of sustaining an injury , and a moderate level of evidence between amphetamine use and the risk of death due to road trauma .
This is the first review to synthesis e evidence regarding the association between amphetamine-type substance use and the risk of injury or death due to a road traffic accident .
More conclusive evidence of death due to road trauma among amphetamine users may reflect significant and global deficits in functioning associated with effective vehicular control under the influence of this substance .
Amphetamine-type substances are frequently detected among drivers injured or killed due to road-trauma .
However , the role of this substance in crash causation remains equivocal .
We performed a systematic review to evaluate existing evidence regarding the association between amphetamine use and the risk of injury or death due to road traffic accidents .