Calcium supplements  increased BMD by 0.7 - 1.8 % at all five skeletal sites at one , two , and over two and a half years , but the size of the increase in BMD at later time points was similar to the increase at one year .
Increasing calcium intake from dietary sources or by taking calcium supplements produces small non-progressive increases in BMD , which are unlikely to lead to a clinical ly significant reduction in risk of fracture
OBJECTIVE To determine whether increasing calcium intake from dietary sources affects  bone mineral density ( BMD ) and , if so , whether the effects are similar to those of calcium supplements .
Calcium supplementation reduces vertebral bone loss in perimenopausal women: a controlled trial in 248 women between 46 and 55 years of age.
To study the effect of calcium supplementation on  perimenopausal bone loss , 295 women were r and omized into a control group and 2 supplementation groups receiving , respectively , 1000 and 2000 mg elemental calcium/day for a period of 2 yr . We observed a significant decrease in lumbar bone loss in relation to the calcium supplementation ( mean loss after 2 yr of 3.5 % in the control group vs. 1.3 % and 0.7 % in the 1000 and 2000 mg groups , respectively ) , a significant increase in urinary calcium excretion , and a significant decrease in the urinary hydroxyproline/creatine ratio , serum alkaline phosphatase , osteocalcin , and 1,25-dihydroxyvitamin D. The effect of calcium supplementation on lumbar bone loss was significant in the first year of supplementation , but not in the second . However , the urinary hydroxyproline/creatinine ratio and the serum alkaline phosphatase level remained significantly decreased in the treatment groups at the end of the study ; this was not the case for serum osteocalcin . Calcium supplementation did not have a significant effect on metacarpal cortical bone loss . The difference in biochemical parameters between the 2 supplementation groups was small . No significant interaction was observed between the menopausal status of the subjects and the effect of calcium supplementation . We conclude that calcium supplementation retards lumbar bone loss in the first year of calcium supplementation by reducing bone turnover . However , the effect on lumbar bone loss over a longer time span is still uncertain
Calcium supplements  increased BMD by 0.7 - 1.8 % at all five skeletal sites at one , two , and over two and a half years , but the size of the increase in BMD at later time points was similar to the increase at one year .
Increasing calcium intake from dietary sources or by taking calcium supplements produces small non-progressive increases in BMD , which are unlikely to lead to a clinical ly significant reduction in risk of fracture
OBJECTIVE To determine whether increasing calcium intake from dietary sources affects  bone mineral density ( BMD ) and , if so , whether the effects are similar to those of calcium supplements .