Four trials that were not combined in meta-analyses suggested that extracts with high ( > 30 mg/d ) levels of genistein consistently reduced the frequency of hot flushes .
BACKGROUND Vasomotor symptoms , such as hot flushes and night sweats , are very common during the menopausal transition .
Hormone therapy has traditionally been used as a highly effective treatment , but concerns about increased risk of some chronic diseases have markedly increased the interest of women in alternative treatments .
Some of the most popular of these treatments are foods or supplements enriched with phytoestrogens-plant-derived chemicals that have estrogenic action .
OBJECTIVES To assess the efficacy , safety and acceptability of food products , extracts and dietary supplements containing high levels of phytoestrogens when compared with no treatment , placebo or hormone therapy for the amelioration of vasomotor menopausal symptoms ( such as hot flushes and night sweats ) in perimenopausal and postmenopausal women .
[Possibilities for an individualized approach to the treatment of climacteric symptoms with phytoestrogens].
UNLABELLED In climacteric women with contraindications and fear or lack of compliance for taking hormonal replacement therapy  as well as in those cases where risks exceed benefits , the use of phytoestrogens is appropriate having in mind their especially good effect on neurovegetative symptoms . AIM The present r and omized prospect i ve study is aim ed at estimating the possibility for ameliorating climacteric symptoms with  Melbrosia  and at assessment of its effect on different symptoms in order to individualize the therapeutical approach . PATIENTS AND METHODS Two groups of women with climacteric complaints were followed-up -- control group ( n = 32 ) and  treatment group ( n = 34 ) . Climateric symptoms were assessed in the beginning and at the end of the study using Kupperman menopausal index . The levels of FSH , LH , oestradiol as well as some parameters of lipid metabolism were determined . RESULTS A significant decrease of Kupperman index was observed in Melbrosia treatment group in contrast to the control group . No significant changes in gonadotropins , oestradiol and lipid parameters were found in both groups . CONCLUSION The preparation Melbrosia , consisting of phytoestrogens and amino acids exerts a good therapeutic effect on climacteric symptoms mainly on the nervousness , anxiety , irritability , headache , and hot flashes
Four trials that were not combined in meta-analyses suggested that extracts with high ( > 30 mg/d ) levels of genistein consistently reduced the frequency of hot flushes .
BACKGROUND Vasomotor symptoms , such as hot flushes and night sweats , are very common during the menopausal transition .
Hormone therapy has traditionally been used as a highly effective treatment , but concerns about increased risk of some chronic diseases have markedly increased the interest of women in alternative treatments .
Some of the most popular of these treatments are foods or supplements enriched with phytoestrogens-plant-derived chemicals that have estrogenic action .
OBJECTIVES To assess the efficacy , safety and acceptability of food products , extracts and dietary supplements containing high levels of phytoestrogens when compared with no treatment , placebo or hormone therapy for the amelioration of vasomotor menopausal symptoms ( such as hot flushes and night sweats ) in perimenopausal and postmenopausal women .