For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?
False positives in breast cancer screening with one-view breast tomosynthesis: An analysis of findings leading to recall, work-up and biopsy rates in the Malmö Breast Tomosynthesis Screening Trial
Abstract Objectives To analyse false positives ( FPs ) in breast cancer screening with tomo synthesis ( BT ) vs. mammography ( DM ) . Methods The Malmö Breast Tomo synthesis Screening Trial ( MBTST ) is a prospect i ve population -based study comparing one-view BT to DM in screening . This study is based on the first half of the MBTST population ( n = 7,500 ) .  Differences in FP recall rate , findings leading to recall , work-up and biopsy rate between cases recalled on BT alone , DM alone and BT+DM were analysed . Results The FP recall rate  was 1.7 % for  BT alone  ( n = 131 ) , 0.9 % for DM alone ( n = 69 ) and 1.1 % for BT + DM ( n = 81 ) . The FP recall rate for BT alone was halved after the initial phase of the trial , stabilising at 1.5 % . BT doubled the recall of stellate distortions compared to DM ( n = 64 vs. n = 33 ) . There were fewer fibroadenomas and cysts , and the biopsy rate was slightly lower for FP recalled on BT alone compared to DM alone ( 15.3 % vs. 27.6 % : p = 0.037 and 33.8 % vs. 36.2 % ; p = 0.641 , respectively ) . Conclusions FPs increased with BT screening mainly due to the recall of stellate distortions . The FP recall rate was still well within the European guidelines and showed evidence of a learning curve . Characterisation of rounded lesions was improved with BT.Key Points• Tomo synthesis screening gave a higher false-positive recall rate than mammography • There was a decline in the false-positive recall rate for tomo synthesis • The recall due to stellate distortions simulating malignancy was doubled with tomo synthesis • Tomo synthesis found more radial and postoperative scar tissue than mammography • Tomo synthesis is better at characterising rounded
For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?