This meta- analysis suggests that probiotic administration may significantly reduce serum CRP while having no significant effect on serum IL10 and TNF-α
We conducted this systematic review and meta- analysis of prospect i ve studies to determine the effect of  probiotic administration on serum C-reactive protein ( CRP ) concentrations .
Effect of Saccharomyces boulardii in Children with Acute Gastroenteritis and Its Relationship to the Immune Response
We evaluated the effect of Saccharomyces boulardii administration in otherwise healthy children aged between 6 months and 10 years who were admitted for acute diarrhoea ( 15 males , 12 females ) . The patients were r and omized into two groups : group 1 ( n = 16 ) received 250 mg S. boulardii dissolved in 5 ml of water orally twice daily for 7 days and group 2 ( n = 11 ) received placebo . Clinical and laboratory assessment s were performed on admission and on day 7 of follow-up . Both groups experienced reduced daily stool frequency , the decrease being significantly greater in group 1 on days 3 and 4 compared with group 2 . Group 1 demonstrated significant increases in serum immunoglobulin A and decreases in C-reactive protein levels on day 7 . The percentage of CD8 lymphocytes on day 7 was significantly higher in group 1 than group 2 . This study confirmed the efficacy of S. boulardii in paediatric acute gastroenteritis and the findings suggest that S. boulardii treatment enhances the immune response
This meta- analysis suggests that probiotic administration may significantly reduce serum CRP while having no significant effect on serum IL10 and TNF-α
We conducted this systematic review and meta- analysis of prospect i ve studies to determine the effect of  probiotic administration on serum C-reactive protein ( CRP ) concentrations .