Conclusion Our results indicate  that L-carnitine  reduced inflammatory mediators , especially in studies with a duration of more than 12 weeks .
Aim and background Reducing inflammation by nutritional supplements may help to reduce the risk of many chronic diseases .
Our aim in this meta- analysis was to determine the effect of L-carnitine on inflammatory mediators including C-reactive protein ( CRP ) , tumor necrosis factor-α ( TNF-α ) , and interleukin-6 ( IL-6 ) .
Effects of acetyl-L-carnitine oral administration on lymphocyte antibacterial activity and TNF-alpha levels in patients with active pulmonary tuberculosis. A randomized double blind versus placebo study.
Acetyl-L-carnitine ( ALC ) , a drug for the treatment of ageing-related neuroendocrine dysfunctions , was orally administered--2 gm/day for 30 days -- to 10 patients with active pulmonary tuberculosis ( TBC ) .  Lymphocyte-mediated antibacterial activity and serum levels of tumor necrosis factor (TNF)-alpha were evaluated before and after treatment , comparing the values with those of 10 TBC patients receiving placebo . Results show that by day 30 , antibacterial activity remained unmodified or increased in ALC-treated subjects , while decreased in the placebo group . No influence of ALC on TNF-alpha levels was detectable . These data suggest that the host 's immune responses to M. tuberculosis infection can be selectively modulated by drugs acting on the neuroendocrine axis
Conclusion Our results indicate  that L-carnitine  reduced inflammatory mediators , especially in studies with a duration of more than 12 weeks .
Aim and background Reducing inflammation by nutritional supplements may help to reduce the risk of many chronic diseases .
Our aim in this meta- analysis was to determine the effect of L-carnitine on inflammatory mediators including C-reactive protein ( CRP ) , tumor necrosis factor-α ( TNF-α ) , and interleukin-6 ( IL-6 ) .