REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .
[Clinical observation on therapeutical effect of prepared rhubarb in treating pregnancy induced hypertension].
OBJECTIVE To study the effect of prepared rhubarb in treating patients with pregnancy induced hypertension ( PIH ) and its therapeutic mechanisms . METHODS Prepared rhubarb and nifedipine were given to the study group , while the nifedipine was given to the control group alone . The blood lipid , renal function , blood coagulation , fibrinolysis and immunological parameters were monitored . RESULTS In the study group , ( 1 ) Levels of triglycerides ( TG ) and low density lipoprotein-cholesterol ( LDL-C ) decreased and high density lipoprotein-cholesterol ( HDL-C ) level increased significantly ; ( 2 ) Plasma level of fibronectin ( FN ) and plasminogen activator inhibitor ( PAI ) lowered significantly , plasma antithrombin ( AT-III ) level unchanged ; ( 3 ) Serum beta 2 microglobulin ( beta 2-MG ) level and urinary level of N-acetyl-beta-D-glucosaminidase ( NAG ) and interleukin-6 ( IL-6 ) decreased significantly ; ( 4 ) CD8 of blood increased , CD4/CD8 and circulating immune complex ( CIC ) of blood reduced obviously . All of the above-mentioned parameters in the study group were significantly different from that of the control group . CONCLUSION The prepared rhubarb could reduce the vascular endothelial cell 's damage significantly and alter the immune balance , which is effective in treating the PIH
REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .