Widespread use of fluoroquinolone prophylaxis may be associated with an increase in resistant Escherichia coli strains , posing a potentially major health issue in the future .
INTRODUCTION Transrectal ultrasound-guided biopsies ( TRUS-gb ) are associated with both mild and serious complications .
Prophylactic antibiotics reduce the risk of septicaemia and mortality ; however , no international consensus exists on the timing and duration of antibiotics , including the optimal drug strategy .
We review ed the current evidence supporting use of prophylactic antibiotics and the risk of complications following prostate biopsies .
Is urine culture routinely necessary before prostate biopsy?
The objective of this study was to assess the value of a urine bacterial culture performed before prostate biopsy . We performed a prospect i ve study on 353 patients who underwent prostate biopsy . All patients had a urine bacterial culture performed before biopsy . We compared the outcomes of patients with bacteriuria ( left untreated ) with those of patients without bacteriuria . Of the 353 men , 12 had a pre-biopsy-positive bacterial culture and underwent prostate biopsy without any infectious complication . Fifteen patients with a negative pre-biopsy culture developed a post-biopsy-positive bacterial culture , but remained asymptomatic without any treatment . Only four men from the group without pre-biopsy bacteriuria developed an infectious complication , requiring 3 weeks of antibiotic therapy . The complication rates were similar for both groups . Our results suggest that routine urine bacterial culture before prostate biopsy is not useful when antibiotic prophylaxis and enema are performed . We do , however , suggest performing a urine bacterial culture before prostate biopsy for patients with a previous history of urinary tract infections
Widespread use of fluoroquinolone prophylaxis may be associated with an increase in resistant Escherichia coli strains , posing a potentially major health issue in the future .
INTRODUCTION Transrectal ultrasound-guided biopsies ( TRUS-gb ) are associated with both mild and serious complications .
Prophylactic antibiotics reduce the risk of septicaemia and mortality ; however , no international consensus exists on the timing and duration of antibiotics , including the optimal drug strategy .
We review ed the current evidence supporting use of prophylactic antibiotics and the risk of complications following prostate biopsies .