RESULTS We found that none of the 19 instruments have sufficiently comprehensive reporting of measurement or feasibility performance as would be required by regulatory authorities .
INTRODUCTION In an accompanying study we reported on the content of several activity rating scales that have been used for muscle disease .
To further aid in achieving consensus we conducted a systematic review to assess the quality of the 19 activity rating scales  design ed specifically for muscle disease .
Clinical trials in Duchenne dystrophy. Standardization and reliability of evaluation procedures.
A multiclinic , collaborative study has been design ed to assess the natural progression and efficacy of treatment of Duchenne muscular dystrophy . This article describes the protocol for the evaluation technique and the method used to establish within ( intraobserver ) and between ( interobserver ) reliability of the protocol evaluation procedures .  St and ardized patient evaluations  were used , and consistency of evaluation was monitored by a computer . The reliability of the measures was analyzed 1 ) within observers by comparing the results of each of the first three tests done by each evaluator for all patients and 2 ) between observers by comparing , at multicenter group meetings , the results of each of the four evaluators ' tests of the same patient . We have demonstrated reliability for an evaluation method that will provide an objective foundation on which to cl aim a drug or therapeutic procedure does or does not have an effect in treating Duchenne muscular dystrophy
RESULTS We found that none of the 19 instruments have sufficiently comprehensive reporting of measurement or feasibility performance as would be required by regulatory authorities .
INTRODUCTION In an accompanying study we reported on the content of several activity rating scales that have been used for muscle disease .
To further aid in achieving consensus we conducted a systematic review to assess the quality of the 19 activity rating scales  design ed specifically for muscle disease .