Subgroup analysis suggested the existence of liver disease at baseline , synbiotics supplementation and duration of supplementation ≥ 8 weeks result ed in more pronounced improvement in liver function enzymes than their counterparts .
Conclusions Probiotics and synbiotics may be suggested as supplements to improve serum concentration of liver enzymes , especially when synbiotics administered for a period ≥ 8 weeks and in individuals with liver disease
Purpose The gut – liver interaction suggests that modification of gut bacterial flora using probiotics and synbiotics may improve liver function .
This systematic review and meta- analysis aim ed to clarify the effect of probiotics and synbiotics consumption on the serum concentration of liver function enzymes .
Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals.
BACKGROUND & AIMS To examine the effect of supplementation with probiotics on respiratory and gastrointestinal illness in healthy active men and women . METHODS A r and omised double-blind placebo-controlled trial was conducted . Four hundred and sixty five participants ( 241 males ; age 35 ± 12 y ( mean ± SD ) and 224 females ; age 36 ± 12 y ) were assigned to one of three groups : Group 1 - Bifidobacterium animalis subsp . lactis Bl-04 ( Bl-04 ) 2.0 × 10(9)colony forming units per day , CFU per day , Group 2 - Lactobacillus acidophilus NCFM and Bifidobacterium animalis subsp . lactis Bi-07 ( NCFM & Bi-07 ) 5 × 10(9 ) CFU each per day ) or Group 3 - placebo mixed in a drink . RESULTS The risk of an upper respiratory illness episode was significantly lower in the Bl-04 group ( hazard ratio 0.73 ; 95 % confidence interval 0.55 - 0.95 ; P = 0.022 ) compared to placebo . There was no significant difference in illness risk between the NCFM & Bi-07 group ( hazard ratio 0.81 ; 0.62 - 1.08 ; P = 0.15 ) and the placebo group . There was a 0.7 and 0.9 month delay in the median time to an illness episode in the Bl-04 and NCFM & Bi-07 groups respectively compared to placebo ( placebo 2.5 months ; Bl-04 3.2 months ; NCFM & Bi-07 3.4 months ) . There were insufficient GI illness episodes for analysis . The NCFM & Bi-07 group but not the Bl-04 group undertook significantly more physical activity ( 8.5 % ; 6.7%-10 % ; P < 0.003 ) than the placebo group . CONCLUSION The probiotic Bl-04 appears to be a useful nutritional supplement in reducing the risk of URTI in healthy physically-active adults . TRIAL REGISTRATION Australia New Zeal and Clinical Trials Registry : Number ACTRN12611000130965
Subgroup analysis suggested the existence of liver disease at baseline , synbiotics supplementation and duration of supplementation ≥ 8 weeks result ed in more pronounced improvement in liver function enzymes than their counterparts .
Conclusions Probiotics and synbiotics may be suggested as supplements to improve serum concentration of liver enzymes , especially when synbiotics administered for a period ≥ 8 weeks and in individuals with liver disease
Purpose The gut – liver interaction suggests that modification of gut bacterial flora using probiotics and synbiotics may improve liver function .
This systematic review and meta- analysis aim ed to clarify the effect of probiotics and synbiotics consumption on the serum concentration of liver function enzymes .