We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .
Serum Antibody Levels to Actinobacillus actinomycetemcomitans Predict the Risk for Coronary Heart Disease
Objective —The association between serum antibody levels to major periodontal pathogens and coronary heart disease ( CHD ) was analyzed in a prospect i ve population -based study . Methods and Results —The population comprised 1023 men ( aged 46 to 64 years ) in the Kuopio Ischemic Heart Disease Study . The subjects with CHD at baseline ( n=113 ) were more often seropositive for Porphyromonas gingivalis IgA ( 38.9 % versus 28.5 % , P=0.021 ) and IgG ( 60.2 % versus 46.7 % , P=0.007 ) than those without CHD . During the 10-year follow-up , 109 men free from CHD at baseline experienced an acute myocardial infa rct ion or CHD death . The men with an end point were more often seropositive for Actinobacillus actinomycetemcomitans IgA ( 15.5 % versus 10.2 % , P=0.019 ) than those who remained healthy . In the highest tertile of A. actinomycetemcomitans IgA-antibodies compared with the lowest one , the relative risk ( RR ) for an end point adjusted for CHD risk factors was 2.0 ( 95 % confidence interval [ CI ] , 1.2 to 3.3 ) . In the Porphyromonas gingivalis IgA-antibody tertiles , the highest RR of 2.1 ( 1.3 to 3.4 ) was observed in the second tertile . All antibody levels correlated positively with the carotid artery intima-media thickness . Conclusions —High-serum antibody levels to major periodontal pathogens are associated with sub clinical , prevalent , and future incidence of CHD . Periodontal pathogens or host response against them may contribute to the pathogenesis of CHD
We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .