There was no consistency among the protocol s regarding length of antibiotic use , discharge criteria , or use of home antibiotics following discharge .
Limiting duration of antibiotic use to3 days did not appear to be associated with higher rates of intraabdominal abscess or wound infection .
In the absence of higher-level evidence , shortening of antibiotic regimens following surgery for pediatric complicated appendicitis appears to be safe
The suitable duration of antibiotic use following appendectomy for advanced appendicitis in children is still debated .
Perforated appendix and antibiotics.
60 consecutive children operated for perforated appendicitis were treated r and omly with either penicillin and streptomycin or with clindamycin and gentamycin .  Suppurative complications occurred somewhat more often and were definitely more severe in the former group . The number of hospital days spent in the treatment of these complications were three times as great in the former than in the latter group . Bacteroides fragilis could be isolated in most of the severe infections treated without clindamycin . Two out of 28 patients treated with clindamycin presented with severe diarrhoea
There was no consistency among the protocol s regarding length of antibiotic use , discharge criteria , or use of home antibiotics following discharge .
Limiting duration of antibiotic use to3 days did not appear to be associated with higher rates of intraabdominal abscess or wound infection .
In the absence of higher-level evidence , shortening of antibiotic regimens following surgery for pediatric complicated appendicitis appears to be safe
The suitable duration of antibiotic use following appendectomy for advanced appendicitis in children is still debated .