We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .
Effects of omega-3 polyunsaturated fatty acids on plasma indices of thrombogenesis and inflammation in patients post-myocardial infarction.
OBJECTIVE To determine the effects of n-3 PUFAs supplementation on plasma indices of coagulation ( fibrinogen ) , fibrin D-Dimer ( an index of thrombogenesis and fibrin turnover ) , endothelial damage/dysfunction ( von Willebr and factor ( vWf ) ) , platelet activation ( soluble P-selectin ( sP-sel ) ) and inflammation ( interleukin-6 , IL-6 ) in patients following acute myocardial infa rct ion . METHODS Open-labelled r and omised controlled trial . Seventy-seven post-myocardial infa rct ion ( MI ) patients stabilized on st and ard secondary prevention therapy were r and omised either to 3 months ' treatment with Omacor 1 g/day ( n=37 ) or ' usual care ' control ( n=40 ) . Plasma levels of fibrinogen , D-Dimer , vWf , sP-sel , IL-6 and plasma viscosity at baseline and after 3 months were determined . RESULTS At baseline , there were no significant differences between the groups in all research indices , except vWf levels were higher in patients allocated to Omacor supplementation . After 3 months , there were no significant changes in the levels of any research indices in either the Omacor supplemented or the ' usual care ' control patients when compared to baseline . Patients who received Omacor experienced a fall in total cholesterol ( p=0.019 ) , total/HDL-cholesterol ratio ( p=0.009 ) and LDL-cholesterol ( p=0.023 ) . However , the relative changes in plasma lipids and lipoproteins did not differ between the two groups . CONCLUSIONS Three-month supplementation of Omacor at 1 g per day in post-MI patients is not associated with an improvement in the levels of peripheral indices of coagulation potential , endothelial function , platelet reactivity and inflammation
We conclude that omega-3 fatty acids may be associated with lower inflammatory biomarkers among diabetic and cardiovascular patients .
The purpose of this systematic review and meta- analysis was to investigate omega-3 fatty acids ’ influence on 12 inflammatory biomarkers — LDL , HDL , total cholesterol , TG , HbA1c , Apo AI , Apo AII , Apo B , CRP , TNF-α , glucose , and fasting blood glucose among diabetic and cardiovascular disease ( CVD ) patients .