Treatment effects on apolipoprotein B and non-HDL cholesterol were not observed .
INTERPRETATION Our findings suggest that dietary pulse intake significantly reduces LDL cholesterol levels .
BACKGROUND Evidence from controlled trials encourages the intake of dietary pulses ( beans , chickpeas , lentils and peas ) as a method of improving dyslipidemia , but heart health guidelines have stopped short of ascribing specific benefits to this type of intervention or have grade d the beneficial evidence as low .
We conducted a systematic review and meta- analysis of r and omized controlled trials ( RCTs ) to assess the effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction .
Hypocholesterolemic effects of oat-bran or bean intake for hypercholesterolemic men.
Oat or bean products , rich in water-soluble fiber , have distinct hypocholesterolemic effects in humans . After a control diet , 20 hypercholesterolemic men were r and omly allocated to oat-bran or bean supplemented diets for 21 days on a metabolic ward . Control and test diets provided equivalent energy , fat , and cholesterol but test diets had twice more total and 3-fold more soluble fiber . Oat-bran diets decreased serum cholesterol concentrations by 19 % ( p less than 0.0005 ) and calculated low-density lipoprotein cholesterol by 23 % ( p less than 0.0025 ) . Bean diets decreased serum cholesterol concentrations by 19 % ( p less than 0.0005 ) and low-density lipoprotein cholesterol by 24 % ( p less than 0.0005 ) . Oat-bran increased fecal weight by 43 % but beans did not . While oat-bran increased fecal bile acid excretion , beans had the opposite effect . Oat-bran or bean supplements may have an important role in nutritional management of selected hypercholesterolemic patients
Treatment effects on apolipoprotein B and non-HDL cholesterol were not observed .
INTERPRETATION Our findings suggest that dietary pulse intake significantly reduces LDL cholesterol levels .
BACKGROUND Evidence from controlled trials encourages the intake of dietary pulses ( beans , chickpeas , lentils and peas ) as a method of improving dyslipidemia , but heart health guidelines have stopped short of ascribing specific benefits to this type of intervention or have grade d the beneficial evidence as low .
We conducted a systematic review and meta- analysis of r and omized controlled trials ( RCTs ) to assess the effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction .