The review established the paucity of high quality evidence investigating the efficacy of psychotherapy combined with benzodiazepines for panic disorder .
Currently , there is inadequate evidence to assess the clinical effects of psychotherapy combined with benzodiazepines for patients who are diagnosed with panic disorder
BACKGROUND The efficacy of combining psychotherapy and benzodiazepines for panic disorder is unclear , despite widespread use .
OBJECTIVES To examine the efficacy of the combination compared with either treatment alone .
Relationship of panic, anticipatory anxiety, agoraphobia and global improvement in panic disorder with agoraphobia treated with alprazolam and exposure.
In a controlled trial of alprazolam and exposure in 154 patients with panic disorder with agoraphobia , relations between panic , anticipatory anxiety , and phobic avoidance were examined . The three symptoms were independent of one another at baseline and improved largely independently during treatment ; only early improvement in avoidance predicted global improvement after treatment . Global improvement was more related to reduction of avoidance than a decrease in panics . Panic was not a valuable outcome measure in panic disorder with agoraphobia
The review established the paucity of high quality evidence investigating the efficacy of psychotherapy combined with benzodiazepines for panic disorder .
Currently , there is inadequate evidence to assess the clinical effects of psychotherapy combined with benzodiazepines for patients who are diagnosed with panic disorder
BACKGROUND The efficacy of combining psychotherapy and benzodiazepines for panic disorder is unclear , despite widespread use .
OBJECTIVES To examine the efficacy of the combination compared with either treatment alone .