Moderate evidence was observed for : ( 1 ) no effect of workstation adjustment , ( 2 ) no effect of rest breaks and exercise and ( 3 ) positive effect of alternative pointing devices .
For all other interventions mixed or insufficient evidence of effect was observed .
Conclusion : Few high quality studies were found that examined the effects of interventions in the office on musculoskeletal or visual health
Background : The literature examining the effects of workstation , eyewear and behavioral interventions on  musculoskeletal and visual symptoms among computer users is large and heterogeneous .
Methods : A systematic review of the literature used a best evidence synthesis approach to address the general question “ Do office interventions among computer users have an effect on musculoskeletal or visual health ? ”
Effects of two eye drop products on computer users with subjective ocular discomfort.
BACKGROUND An increasing number of people seek medical attention for symptoms of visual discomfort due to computer vision syndrome ( CVS ) . We compared the efficacy and adverse event rates of a new eye lubricant , OptiZen ( InnoZen , Inc. , polysorbate 80 0.5 % ) and Visine Original ( Pfizer Consumer Healthcare , tetrahydrozoline HCl 0.05 % ) . METHODS In this double-blind parallel arm trial , 50 healthy men and women , ages 18 to 65 years , with symptoms of CVS who use a video display terminal for a minimum of 4 hours per day were  r and omized to OptiZen ( n = 25 ) or Visine Original ( n= 25 ) , 1 to 2 drops b.i.d . for 5 days . The primary end-points were ocular discomfort and adverse events . RESULTS OptiZen and Visine Original had similar efficacy in alleviating symptoms of ocular discomfort ( odds ratio of 1.23 [ 95 % confidence interval , 0.63 to 2.42 ] , P= 0.55 ) . OptiZen and Visine Original were very similar with respect to odds ratios and 95 % confidence interval ( CI ) for each of the measurement times ( P= 0.72 ) . Visine Original users reported a significantly higher incidence of temporary ocular stinging/burning immediately after drug instillation ( 28 % , 7/25 ) than did OptiZen users ( 4 % , 1/24 ) ( P= 0.05 ) . Patients using  OptiZen were 89 % less likely to have stinging/burning effects than those patients using Visine Original ( 95 % CI : 0.01 to 0.95 ) . DISCUSSION OptiZen and Visine Original are effective at alleviating ocular discomfort associated with prolonged computer use . Adverse event findings suggest that OptiZen causes less ocular discomfort on instillation , potentially attributable to its milder ingredient profile
Moderate evidence was observed for : ( 1 ) no effect of workstation adjustment , ( 2 ) no effect of rest breaks and exercise and ( 3 ) positive effect of alternative pointing devices .
For all other interventions mixed or insufficient evidence of effect was observed .
Conclusion : Few high quality studies were found that examined the effects of interventions in the office on musculoskeletal or visual health
Background : The literature examining the effects of workstation , eyewear and behavioral interventions on  musculoskeletal and visual symptoms among computer users is large and heterogeneous .
Methods : A systematic review of the literature used a best evidence synthesis approach to address the general question “ Do office interventions among computer users have an effect on musculoskeletal or visual health ? ”