Sensitivity analyses and meta-regression for hemoglobin suggested a higher response with lower trial quality ( suboptimal allocation concealment and blinding ) , use of condiments , and sodium iron edetate and a lower response when adults were included .
Consumption of iron-fortified foods results in an improvement in hemoglobin , serum ferritin , and iron nutriture and a reduced risk of remaining anemic and iron deficient
BACKGROUND The utility of iron fortification of food to improve iron deficiency , anemia , and biological outcomes is not proven unequivocally .
Prevention of anaemia in inner city toddlers by an iron supplemented cows' milk formula.
There are few data to support the use of follow-on formulas in infants from the age of 6 months . In a prospect i ve trial in a deprived inner city area of Birmingham 100 infants who were already receiving pasteurised cows ' milk by 6 months of age were enrolled and r and omised either to receive a follow-on formula or to continue on cows ' milk from 6 months until 18 months . At 18 months of age the follow-on formula group returned to cows ' milk and both groups were followed up until 24 months . Iron status , growth , and nutritional status were analysed at intervals of six months . At enrollment , no differences in haematological status were evident . However , by 12 months of age , 31 % of the cows ' milk group were anaemic ( haemoglobin concentration < 110 g/l ) compared with only 3 % of those receiving follow-on formulas . At 18 months , 33 % of the cows ' milk group were anaemic compared with only 2 % of the follow-on formula group and by 24 months of age none of the follow-on formula group was anaemic , whereas 26 % in the cows ' milk group still had a haemoglobin of < 110 g/l . Mean corpuscular volume was significantly smaller and ferritin significantly lower in the cows ' milk group at 12 , 18 , and 24 months . Dietary iron intake was higher in the follow-on formula group at 12 and 18 months but not at 24 months , when both groups were back on cows ' milk . Infants and toddlers at high risk of iron deficiency are therefore unlikely to become anaemic if receiving a follow-on formula , although the relative merits of follow-on formula compared with an ordinary infant formula remain uncertain
Sensitivity analyses and meta-regression for hemoglobin suggested a higher response with lower trial quality ( suboptimal allocation concealment and blinding ) , use of condiments , and sodium iron edetate and a lower response when adults were included .
Consumption of iron-fortified foods results in an improvement in hemoglobin , serum ferritin , and iron nutriture and a reduced risk of remaining anemic and iron deficient
BACKGROUND The utility of iron fortification of food to improve iron deficiency , anemia , and biological outcomes is not proven unequivocally .