T2D prevention by physical activity or diet or both proved cost-effective according to accepted thresholds , except for five inconclusive studies , three on diabetes prevention and two on obesity control .
This confirms that lifestyle interventions for the primary prevention of diabetes are cost-effective .
To summarize key findings of economic evaluations of lifestyle interventions for the primary prevention of  type 2 diabetes ( T2D ) in high-risk subjects .
Cost-effectiveness of a primary care intervention to treat obesity
Background : Data on the cost-effectiveness of the behavioral treatment of obesity are not conclusive . The cost-effectiveness of treatment in primary care setting s is particularly relevant . Methods : We conducted a within-trial cost-effectiveness analysis of a primary care-based obesity intervention .  Study participants were r and omized to : Usual Care ( UC ; quarterly visits with their primary care provider ) ; Brief Lifestyle Counseling ( BLC ; quarterly provider visits plus monthly weight loss counseling visits ) or Enhanced Brief Lifestyle Counseling ( EBLC ; all above interventions  ,  plus choice of meal replacements or weight loss medication )  . A health-care payer perspective was used . Intervention costs were estimated from tracking data obtained prospect ively . Quality -adjusted life years ( QALYs ) were estimated with the EuroQol-5D . We estimated cost per kilogram-year of weight loss and cost per QALY . Results : Weight losses after 2 years were 1.7 , 2.9 and 4.6 kg for UC , BLC and EBLC , respectively ( P=0.003 for comparison of EBLC vs UC ) . The incremental cost per kilogram-year lost was $ 292 for EBLC compared with UC ( 95 % confidence interval ( CI ) : $ 219–$437 ) . The short-term incremental cost per QALY was $ 115 397 , but the 95 % CI were undefined . Comparison of short-term cost per kg with published estimates of longer-term cost per QALY suggested that the intervention could be cost-effective over the long term ( ⩾10 years ) . Conclusions : A primary care intervention that includes monthly counseling visits and a choice of meal replacements or weight loss medication could be a cost-effective treatment for obesity over the long term . However , additional studies are needed on the cost-effectiveness of behavioral treatment of obesity
T2D prevention by physical activity or diet or both proved cost-effective according to accepted thresholds , except for five inconclusive studies , three on diabetes prevention and two on obesity control .
This confirms that lifestyle interventions for the primary prevention of diabetes are cost-effective .
To summarize key findings of economic evaluations of lifestyle interventions for the primary prevention of  type 2 diabetes ( T2D ) in high-risk subjects .