The majority of adverse events associated with CNTKA were minor and comparable with those seen with conventional TKA .
Clinical outcomes were comparable between the two techniques , with longer-term follow-up suggesting that CNTKA provided no benefit over conventional TKA in terms of sustained functional improvements .
At present , it is unclear whether the significant improvements shown in radiological outcomes after CNTKA translate to measurable clinical benefits .
BACKGROUND Conventional total knee arthroplasty ( TKA ) and the more recently available computer-navigated total knee arthroplasty ( CNTKA ) use alternative methods to achieve correct limb alignment .
This systematic review was undertaken to assess the safety and effectiveness of CNTKA compared with conventional TKA .
Are systemic emboli reduced in computer-assisted knee surgery?: A prospective, randomised, clinical trial.
We undertook a prospect i ve , r and omised study using a non-invasive transcranial Doppler device to evaluate cranial embolisation in  computer-assisted navigated total knee arthroplasty ( n = 14 ) and compared this with a st and ard conventional surgical technique using intramedullary alignment guides ( n = 10 ) . All patients were selected r and omly without the knowledge of the patient , anaesthetists ( before the onset of the procedure ) and ward staff . The operations were performed by a single surgeon at one hospital using a uniform surgical approach , instrumentation , technique and release sequence . The only variable in the two groups of patients was the use of single tracker pins of the imageless navigation system in the tibia and femur of the navigated group and intramedullary femoral and tibial alignment jigs in the non-navigated group . Acetabular Doppler signals were obtained in 14 patients in the computer-assisted group and nine ( 90 % ) in the conventional group , in whom high-intensity signals were detected in seven computer-assisted patients ( 50 % ) and in all of the non-navigated patients . In the computer-assisted group no patient had more than two detectable emboli , with a mean of 0.64 ( SD 0.74 ) . In the non-navigated group the number of emboli ranged from one to 43 and six patients had more than two detectable emboli , with a mean of 10.7 ( sd 13.5 ) . The difference between the two groups was highly significant using the Wilcoxon non-parametric test ( p = 0.0003).Our findings show that computer-assisted total knee arthroplasty , when compared with conventional jig-based surgery , significantly reduces systemic emboli as detected by transcranial Doppler ultrasonography
The majority of adverse events associated with CNTKA were minor and comparable with those seen with conventional TKA .
Clinical outcomes were comparable between the two techniques , with longer-term follow-up suggesting that CNTKA provided no benefit over conventional TKA in terms of sustained functional improvements .
At present , it is unclear whether the significant improvements shown in radiological outcomes after CNTKA translate to measurable clinical benefits .
BACKGROUND Conventional total knee arthroplasty ( TKA ) and the more recently available computer-navigated total knee arthroplasty ( CNTKA ) use alternative methods to achieve correct limb alignment .
This systematic review was undertaken to assess the safety and effectiveness of CNTKA compared with conventional TKA .