This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
A COMPARISON OF SERUM LEVELS OF 25-HYDROXY VITAMIN D IN PREGNANT WOMEN AT RISK FOR GESTATIONAL DIABETES MELLITUS AND WOMEN WITHOUT RISK FACTORS
Background : During pregnancy , Low serum 25-hydroxyvitamin-D [ 25(OH)D ] concentration is even more critical . This deficiency leads to higher incidences of preeclampsia , gestational diabetes , preterm birth , bacterial vaginosis , and also affects the health of the infants . The aim of this study was to evaluate the relationships between serum levels of 25-hydroxyvitamin D ( 25[OH]D )  and gestational diabetes mellitus ( GDM ) and differences in high-risk pregnant women and women without risk factors for GDM . Methods : This cross sectional study including 155 pregnant women , who are still in the first trimester of pregnancy ( less than 12 weeks gestation ) , were r and omized to two groups of high and low risk for GDM . For these people , once at the gestational age less than 12 times a week and once at for 24 to 28 weeks of pregnancy , tests of FBS / BS / HbA1C / 25OHD / insulin / Ca / Albumin was requested . Besides , the OGTT test was performed with 75 g glucose at 24 and 28 weeks of pregnancy to diagnose GDM . Results : Serum levels of 25(OH)D in the second trimester of pregnancy ng / ml ( 24.1 ± 39.5 ) was significantly lower than that of the first trimester ng / ml ( 25.9 ± 45.6 ) ( p < 0.001 ) . But serum 25(OH)D levels in the first and second trimester of pregnancy was significantly different in women at high risk for GDM than women who had no risk factors ( p = 0.584 and p = 0.99 ) . Serum levels of 25(OH)D has an inverse and significant relationship with HbA1C at the beginning of pregnancy ( p=0.007 ) . In addition , a significant and inverse relationship was shown between serum levels of 25(OH)D in the second trimester with insulin ( p=0.047 ) and blood sugar 2 hours after ingestion of 75 g glucose ( p=0.045 ) at 24 - 28 weeks of gestation . Conclusion : Regarding to the relationship between serum levels of 25(OH)D and blood sugar and insulin at the second trimester of pregnancy , it is recommended for pregnant women to take vitamin D supplementation
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .