Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
Effect of oatbran on mild hyperlipidaemia.
OBJECTIVE To determine whether adding 60 g oatbran per day to a low saturated fat ,  low cholesterol  diet has any additional effect of lowering serum lipids . DESIGN A double blind , prospect i ve , r and omised , placebo controlled crossover study . SETTING Lipid clinic in a teaching hospital . SUBJECTS Thirty-seven subjects ( 16 men , 21 women ) with serum cholesterol of 5.5 - 8.0 mmol/L were recruited from staff and medical clinics . All subjects were aware of their hyperlipidaemia and no subject was previously treated with lipid lowering agents . INTERVENTIONS After an eight-week diet period subjects were r and omised to receive two muffins per day containing either 60 g of oatbran or the equivalent amount of fibre from wheatbran in a double blind crossover study . MAIN OUTCOME MEASURES Measurement of lipids , lipoproteins and biochemical parameters at the end of each eight-week period . RESULTS Mean serum lipid levels at the end of the oatbran and wheatbran periods were significantly different from each other only for low density lipoprotein ( LDL ) cholesterol ( oatbran , 4.67 mmol/L ; SD , 0.85 ; and wheatbran , 4.95 mmol/L ; SD , 0.81 ; P < 0.01 ) , the LDL/HDL ( high density lipoprotein ) ratio ( oatbran , 3.68 ; SD , 1.25 ; and wheatbran , 4.01 ; SD , 1.25 ; P < 0.001 ) and apoprotein B ( oatbran , 1.03 g/L ; SD , 0.21 ; and wheatbran , 1.08 g/L ; SD , 0.19 ; P < 0.05 ) . CONCLUSION Oatbran fibre is more effective than wheatbran fibre in lowering cholesterol in subjects with mild hyperlipidaemia who are already on a low saturated fat , low cholesterol diet
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .