In addition , AAS abuse result ed in structural and functional sperm changes , a reduction in testicular volume , gynecomastia , as well as clitoromegaly , menstrual irregularities , and subfertility .
Conclusion The majority of  AAS users demonstrated hypogonadism with persistently low gonadotropin and testosterone levels , lasting for several weeks to months after AAS withdrawal .
Anabolic and rogenic steroid use results in profound and prolonged effects on the reproductive system of athletes and recreational users and potentially on fertility
Background Anabolic and rogenic steroids ( AAS ) are testosterone derivatives used by athletes and recreational users to improve athletic performance and /or enhance appearance .
Anabolic and rogenic steroids use may have serious and potentially irreversible adverse effects on different organs and systems , including the reproductive system .
Objective This systematic review and meta- analysis aim ed to critically assess the impact of AAS use on the reproductive system of athletes and recreational users .
Effect of short-term treatment with an anabolic steroid (methandienone) and dehydroepiandrosterone sulphate on plasma hormones, red cell volume and 2,3-diphosphoglycerate in athletes.
The effects of a one-month course of treatment with a potent anabolic steroid , meth and ienone ( 5 and 10 mg daily ) , and a very weak and rogen and hormone precursor , dehydroepi and rosterone sulphate ( DHEAS , 20 and 40 mg daily ) and placebo on plasma testosterone , LH and FSH levels , red cell volume and red cell 2,3-diphosphoglycerate ( 2,3-DPG ) concentration in endurance sportsmen were studied using a double-blind test system . A highly significant decrease in mean plasma testosterone was observed after the 5 and 10 mg meth and ienone regimen ( 66 and 73 % ) . Treatment with 40 mg of DHEAS decreased mean testosterone levels by 41 % ( not statistically significant ) . Pre-test testosterone levels were reattained about 10 days after the end of the treatment period with the higher doses of both compounds , while 2–6 weeks afterwards a significant over-compensation in mean plasma testosterone levels was observed . No significant changes in plasma gonadotropins were seen immediately after treatment with either of these steroids bu
In addition , AAS abuse result ed in structural and functional sperm changes , a reduction in testicular volume , gynecomastia , as well as clitoromegaly , menstrual irregularities , and subfertility .
Conclusion The majority of  AAS users demonstrated hypogonadism with persistently low gonadotropin and testosterone levels , lasting for several weeks to months after AAS withdrawal .
Anabolic and rogenic steroid use results in profound and prolonged effects on the reproductive system of athletes and recreational users and potentially on fertility
Background Anabolic and rogenic steroids ( AAS ) are testosterone derivatives used by athletes and recreational users to improve athletic performance and /or enhance appearance .
Anabolic and rogenic steroids use may have serious and potentially irreversible adverse effects on different organs and systems , including the reproductive system .
Objective This systematic review and meta- analysis aim ed to critically assess the impact of AAS use on the reproductive system of athletes and recreational users .