The longest trial intervention studies did not show a difference in weight change .
This review shows that there are no consistent differences in weight and A1C changes over the long-term treatment with LCD and LFD , UCD or LGID
INTRODUCTION Low carbohydrate diets ( LCD ) have shown beneficial effects on short-term weight reduction programs for obese individuals without diabetes , but the long-term evidence of efficacy on individuals with type 2 diabetes is not conclusive .
OBJECTIVE To evaluate , the effectiveness of 12 or more weeks of LCD compared to Low Fat Diet ( LFD ) , Usual Care Diet ( UCD ) or Low Glycemic Index Diet ( LGID ) on weight reduction and AIC on type 2 diabetes individuals .
Clinical Efficacy of Two Hypocaloric Diets That Vary in Overweight Patients With Type 2 Diabetes
Approximately 80 % of patients with type 2 diabetes are overweight/obese ( 1 ) , and weight loss is the mainstay of treatment for these individuals . However , there is growing controversy as to whether reduced-fat or reduced-carbohydrate diets are best suited for this purpose , and results ( 2–8 ) in nondiabetic subjects suggest that lower carbohydrate diets are similarly or more efficacious in improving weight , triglycerides , and HDL cholesterol . There are no published r and omized studies evaluating the role of dietary macronutrients with respect to weight loss and cardiovascular risk improvement in patients with type 2 diabetes . Thus , we r and omized diet-treated patients with type 2 diabetes to hypocaloric diets , moderately restricted in either carbohydrate or fat , to determine whether weight loss or metabolic improvement differed as a function of macronutrient composition . A total of 29 patients with diet-treated type 2 diabetes were recruited from the San Francisco Bay area . All subjects gave written informed consent . Inclusion criteria included BMI 27–36 kg/m2 , fasting plasma glucose concentration 7.2–8.3 mmol/l , no use of antihyperglycemic medications , and stable weight for 3 months . Subjects on anti-hypertensive or cholesterol-lowering drugs or aspirin were allowed to continue their medications . Insulin-mediated glucose uptake was quantified by a modification ( 9 ) of the insulin suppression test as originally described ( 10 ) and vali date d ( 11 ) . In this test , a 180-min infusion of somatostatin ( 0.27 μg/m2 per min ) , insulin ( 25 mU/m2 per min ) ,
The longest trial intervention studies did not show a difference in weight change .
This review shows that there are no consistent differences in weight and A1C changes over the long-term treatment with LCD and LFD , UCD or LGID
INTRODUCTION Low carbohydrate diets ( LCD ) have shown beneficial effects on short-term weight reduction programs for obese individuals without diabetes , but the long-term evidence of efficacy on individuals with type 2 diabetes is not conclusive .
OBJECTIVE To evaluate , the effectiveness of 12 or more weeks of LCD compared to Low Fat Diet ( LFD ) , Usual Care Diet ( UCD ) or Low Glycemic Index Diet ( LGID ) on weight reduction and AIC on type 2 diabetes individuals .