This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .
Comparison of N2O and CO2 pneumoperitoneums during laparoscopic cholecystectomy with special reference to postoperative pain.
To study the possible benefits of N2O pneumoperitoneum , 40 patients scheduled for laparoscopic cholecystectomy for symptomatic cholelithiasis were r and omized into either CO2-induced ( n = 20 ) or N2O-induced ( n = 20 ) pneumoperitoneum groups . The intensity of postoperative pain was assessed by the patients themselves using an visual analogue pain score scale .  CO2 insufflation caused respiratory acidosis . The total amount of anesthetic enflurane needed was lower in the N2O than in the CO2 group ( p < 0.041 ) . The N2O group experienced less pain 1 hour ( p < 0.040 ) and 6 hours ( p < 0.017 ) postoperatively and the next morning . Serum cortisol and plasma adrenaline concentrations in the N2O group did not differ from those in the CO2 group . Patients with N2O pneumoperitoneum seem to have less pain without the side effects caused by CO2 . The N2O pneumoperitoneum is a good alternative to the CO2 pneumoperitoneum , especially for prolonged laparoscopic operations in patients with chronic cardiopulmonary diseases
This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .