OC could significantly reduce the occurrence of VAP , and consequently , its routine use should be considered for VLBWs to prevent infectious diseases .
OC  significantly reduces the occurrence of VAP and NEC in VLBW infants  .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP .
OC significantly reduces the occurrence of VAP and NEC in VLBW infants .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP
Oropharyngeal colostrum ( OC ) is a novel feeding strategy to prevent complications of prematurity .
A meta- analysis was conducted to investigate whether very low birth weight infants ( VLBWs ) can benefit from OC .
Ventilator-associated pneumonia in the pediatric intensive care unit: characterizing the problem and implementing a sustainable solution.
OBJECTIVES To characterize ventilator-associated pneumonia ( VAP ) in our pediatric intensive care unit ( PICU ) , implement an evidence -based pediatric VAP prevention bundle , and reduce VAP rates . STUDY DESIGN The setting is a 25-bed PICU in a 475-bed free-st and ing pediatric academic medical center . VAP was diagnosed according to Centers for Disease Control and National Nosocomial Infections Surveillance System definitions . A pediatric VAP prevention bundle was established and implemented . Baseline VAP rates were compared with implementation and post-bundle-implementation periods . RESULTS VAP is significantly associated with increased PICU length of stay , mechanical ventilator days , and mortality rates ( length of stay VAP 19.5+/-15.0 vs non-VAP 7.5+/-9.2 , P < .001 ; ventilator days VAP 16.3+/-14.7 vs non-VAP 5.3+/-8.4 , P < .001 ; mortality VAP 19.1 % vs non-VAP 7.2 % , P= .01 ) . The VAP rate was reduced from 5.6 ( baseline ) to 0.3 infections per 1000 ventilator days after bundle implementation ; P < .0001 . Subglottic/tracheal stenosis , trauma , and tracheostomy are significantly associated with VAP . CONCLUSIONS PICU VAP is associated with increased morbidity and mortality rates . A multidisciplinary improvement team can implement a sustainable pediatric-specific VAP prevention bundle , result ing in VAP rate reduction
OC could significantly reduce the occurrence of VAP , and consequently , its routine use should be considered for VLBWs to prevent infectious diseases .
OC  significantly reduces the occurrence of VAP and NEC in VLBW infants  .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP .
OC significantly reduces the occurrence of VAP and NEC in VLBW infants .
OC may reduce the incidence of VAP and NEC by increasing IgA levels .
Early OC therapy for mechanical ventilation of low-weight infants may prevent the occurrence of VAP
Oropharyngeal colostrum ( OC ) is a novel feeding strategy to prevent complications of prematurity .
A meta- analysis was conducted to investigate whether very low birth weight infants ( VLBWs ) can benefit from OC .