The National Eye Institute Visual Function Question naire-25 , Impact of Vision Impairment and Treatment Satisfaction Survey-Intraocular Pressure had the highest number of positive ratings in the content validity assessment .
Conclusion This study provides a descriptive catalogue of vision-specific PRO instruments , to inform the choice of an appropriate measure of patient-reported outcomes in a glaucoma context
Purpose To identify  vision Patient-Reported Outcomes instruments relevant to glaucoma and assess their content validity .
Quality of life in newly diagnosed glaucoma patients : The Collaborative Initial Glaucoma Treatment Study.
OBJECTIVE The Collaborative Initial Glaucoma Treatment Study ( CIGTS ) was design ed to determine whether patients with newly diagnosed open-angle glaucoma are better treated initially by medicine or immediate filtering surgery . This paper describes the quality -of-life ( QOL ) measurement approach , instruments included , and the CIGTS participants ' QOL findings at the time of diagnosis . DESIGN Baseline results from a r and omized , controlled clinical trial . PARTICIPANTS Six hundred seven patients from 14 clinical centers were enrolled . INTERVENTION Patients r and omized to initial medication received a stepped medical regimen ( n = 307 ) . Those r and omized to initial surgery underwent a trabeculectomy ( n = 300 ) . The baseline interview was conducted before treatment initiation . All baseline and posttreatment  QOL assessment s were conducted by telephone from a central ized interviewing center . MAIN OUTCOME MEASURES The primary outcome measure described in this paper was QOL . The QOL instrument is multidimensional and incorporates both disease-specific and generic measures , including the Visual Activities Question naire , Sickness Impact Profile , and a Symptom and Health Problem CHECKLIST : RESULTS The correlations between QOL measures and clinical outcomes were in the expected direction , but relatively weak . At initial diagnosis , difficulty with bright lights and with light and dark adaptation were the most frequently reported symptoms related to visual function , whereas visual distortion was the most bothersome . Approximately half of the patients reported at least some worry or concern about the possibility of blindness . Within the Visual Activities Question naire , higher scores on the Peripheral Vision subscale were associated with more field loss ( P < 0.01 ) . In regression analyses controlling for sociodemographics and nonocular comorbidities , increased visual field loss was significantly associated with higher dysfunction among five disease-specific QOL measures ( P < 0.05 ) . CONCLUSIONS Newly diagnosed glaucoma patients reported experiencing some visual function symptoms at the time of diagnosis that would not be intuitively expected based on clinical testing . Some discussion about the association between clinical presentation and worry about blindness may reduce unnecessary concern . These results provide the basis for long-term comparisons of the QOL effects of initial medical and surgical treatment for open-angle glaucoma
The National Eye Institute Visual Function Question naire-25 , Impact of Vision Impairment and Treatment Satisfaction Survey-Intraocular Pressure had the highest number of positive ratings in the content validity assessment .
Conclusion This study provides a descriptive catalogue of vision-specific PRO instruments , to inform the choice of an appropriate measure of patient-reported outcomes in a glaucoma context
Purpose To identify  vision Patient-Reported Outcomes instruments relevant to glaucoma and assess their content validity .