There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .
Insulin receptor binding increased by high carbohydrate low fat diet in non-insulin-dependent diabetics.
In comparison to a traditional low carbohydrate diet ( LC ) , the effect of an isocaloric high carbohydrate , high fibre diet ( HC ) upon the insulin binding to mononuclear blood cells of seven non-insulin-dependent diabetics was examined . Each subject , in r and om order , took both diets for 6 weeks each . There was no significant difference in weight during either dietary period , but a significant ( P less than 0.05 ) increase in the monocyte insulin binding activity on the HD diet ( tracer specific binding : 4.2 % HC ; 3.5 % LC ) . This was accompanied by a significantly ( P less than 0.02 ) lower fasting plasma glucose concentration ( LC = 7.1 mmol/l ; HC = 6.1 ) without a significant change in the fasting plasma insulin level . In contrast to the usual low carbohydrate diet , a high carbohydrate diet tends to correct the lowered insulin receptor status observed in maturity-onset diabetics
There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .