Among the outcomes examined , the highest absolute risk increase was for heart failure .
Associations between atrial fibrillation and included outcomes were broadly consistent across subgroups and in sensitivity analyses .
Atrial fibrillation is associated with an increased risk of death and an increased risk of cardiovascular and renal disease .
OBJECTIVE To quantify the association between  atrial fibrillation and cardiovascular disease , renal disease , and death .
The European CRT Survey: 1 year (9-15 months) follow-up results.
AIMS The European CRT Survey is a joint initiative of the Heart Failure Association ( HFA ) and the European Heart Rhythm Association ( EHRA ) of the European Society of Cardiology evaluating the contemporary implantation practice of cardiac resynchronization therapy ( CRT ) in Europe . METHODS AND RESULTS Patients who had a successful CRT implantation were enrolled from 141 centres in 13 countries between November 2008 and June 2009 . Baseline demographics , clinical and implantation data were collected , with a follow-up of ∼1 year ( 9 - 15 months ) . The current report describes clinical outcomes including symptom severity , cardiovascular ( CV ) hospitalization , and survival . A total of 2438 patients were enrolled , and follow-up data were acquired from 2111 patients ( 87 % ) . The population included important groups of patients poorly represented in r and omized controlled trials , including very elderly patients and those with prior device implantation , atrial fibrillation , and /or QRS duration < 120 ms . Investigators reported substantial improvement in New York Heart Association ( NYHA ) functional class at follow-up . Patient self- assessment indicated that 81 % of the patients felt improved , 16 % reported no change , and 4 % reported deterioration . During follow-up , 207 ( 10 % ) patients died , 346 ( 16 % ) had a CV hospitalization , and 501 ( 24 % ) died or had CV hospitalization . Worse NYHA functional class , atrial fibrillation , ischaemic aetiology , and device type ( CRT-P , i.e. CRT alone ) were associated with poorer survival . Women had a better outcome , as did patients who had a  CRT-D  ( with an implantable cardioverter defibrillator function ) device . CONCLUSIONS Outcomes including death and hospitalization in this European CRT survey were consistent with results from clinical trials of CRT . At 1 year follow-up , most patients who received a CRT device considered their symptoms improved compared with their pre-implant assessment . Although prospect i ve , this is an observational study of successful CRT implantations , and outcomes in subgroup analyses must be interpreted with appropriate conservatism
Among the outcomes examined , the highest absolute risk increase was for heart failure .
Associations between atrial fibrillation and included outcomes were broadly consistent across subgroups and in sensitivity analyses .
Atrial fibrillation is associated with an increased risk of death and an increased risk of cardiovascular and renal disease .
OBJECTIVE To quantify the association between  atrial fibrillation and cardiovascular disease , renal disease , and death .