Quantitative relations between baseline iron status , study duration , and iron dose on changes in iron-status biomarkers , which were generated from the meta-analyses , can be used to predict effects of trials of iron supplementation and fortification and to design iron-intervention programs
BACKGROUND The response of status biomarkers to an increase in iron supply depends on several physiologic and environmental factors , which make it difficult to predict the outcome of an intervention .
OBJECTIVE We assessed effects of baseline iron status , sex , menopausal status , duration of intervention , iron form , and daily dose on the change in iron status in response to iron supplementation .
Effects of long-term moderate exercise on iron status in young women.
The impact of long-term ( 6-month ) moderate exercise on the iron status of previously sedentary women was determined by r and omly assigning 62 college-age women into one of the following four groups : 1 ) 50 mg.d-1 iron supplement , low iron diet ( N = 16 ) ; 2 ) Placebo , free choice diet ( N = 13 ) ; 3 ) Meat supplement to achieve 15 mg.d-1 iron intake ( N = 13 ) ; and 4 ) Control , free choice diet ( N = 20 ) . All groups except the Control group exercised 3 d.wk-1 at 60%-75 % of their heart rate reserve . VO2max was measured at baseline and week 24 . Blood was sample d at baseline and every 4 wk thereafter for 24 wk to measure iron status and to eluci date the causes for alterations in iron status . Subjects had depleted iron stores throughout the study as indicated by their serum ferritin levels ( < 15 ng.ml-1 ) . Serum iron , total iron binding capacity and transferrin saturation were not compromised with exercise . Mean hemoglobin level in the Placebo/Ex group was significantly ( P < 0.05 ) lower than the 50 Fe/Ex and the Meat/Ex groups by week 24 . However , changes in serum albumin , haptoglobin , and erythropoietin data from the study can not explain these changes
Quantitative relations between baseline iron status , study duration , and iron dose on changes in iron-status biomarkers , which were generated from the meta-analyses , can be used to predict effects of trials of iron supplementation and fortification and to design iron-intervention programs
BACKGROUND The response of status biomarkers to an increase in iron supply depends on several physiologic and environmental factors , which make it difficult to predict the outcome of an intervention .
OBJECTIVE We assessed effects of baseline iron status , sex , menopausal status , duration of intervention , iron form , and daily dose on the change in iron status in response to iron supplementation .