The association between poor performance on SPPB and all-cause mortality remained highly consistent independent of follow-up length , subsets of participants , geographic area , and age of the population .
Conclusions An SPPB score lower than 10 is predictive of all-cause mortality .
The systematic implementation of the SPPB in clinical practice setting s may provide useful prognostic information about the risk of all-cause mortality .
Background The Short Physical Performance Battery ( SPPB ) is a well-established tool to assess lower extremity physical performance status .
Its predictive ability for all-cause mortality has been sparsely reported , but with conflicting results in different subsets of participants .
The aim of this study was to perform a meta- analysis investigating the relationship between SPPB score and all-cause mortality  .
The relationship of physical performance with HIV disease and mortality
Objective : To evaluate whether HIV infection was associated with reduced physical performance , and to examine if reduced physical performance predicted mortality in our aging cohort of HIV-infected and HIV-uninfected persons . Design : Prospect i ve , observational cohort of current and former injection drug users in the AIDS Linked to the IntraVenous Experience study in Baltimore , Maryl and , USA . Methods : The  Short Physical Performance Battery ( SPPB )  was used as an objective measure of physical performance and measured semiannually along with behavioral and demographic data . Correlates of reduced physical performance ( SPPB score ⩽10 ) were identified and the relationship between reduced physical performance , HIV infection and mortality was analyzed by Cox regression . Results : Among 12 270 person-visits contributed by 1627 participants , the median age was 51 , 30.3 % were HIV-infected and 32.6 % had an SPPB score 10 or less . In multivariable models , HIV infection was independently associated with 30 % increased odds of reduced physical performance [ odds ratio 1.30 ; 95 % confidence interval (CI):1.12–1.52 ] . Reduced physical performance predicted mortality in a dose-response manner and within all HIV disease strata . Whereas reduced physical performance alone ( hazard ratio 2.52 , 95 % CI : 1.59–4.00 ) and HIV infection alone ( hazard ratio 2.78 , 95 % CI : 1.70–4.54 ) increased mortality , HIV-infected participants with reduced physical performance had a six-fold increased mortality risk ( hazard ratio 6.03 , 95 % CI : 3.80–10.0 ) compared with HIV-uninfected participants with higher physical performance . Conclusion : HIV infection was independently associated with reduced physical performance . HIV and reduced physical performance have independent and joint effects on mortality . Physical performance measurement may be an important research and clinical tool to predict adverse outcomes among aging HIV-infected persons
The association between poor performance on SPPB and all-cause mortality remained highly consistent independent of follow-up length , subsets of participants , geographic area , and age of the population .
Conclusions An SPPB score lower than 10 is predictive of all-cause mortality .
The systematic implementation of the SPPB in clinical practice setting s may provide useful prognostic information about the risk of all-cause mortality .
Background The Short Physical Performance Battery ( SPPB ) is a well-established tool to assess lower extremity physical performance status .
Its predictive ability for all-cause mortality has been sparsely reported , but with conflicting results in different subsets of participants .
The aim of this study was to perform a meta- analysis investigating the relationship between SPPB score and all-cause mortality  .