For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?
Two-view digital breast tomosynthesis screening with synthetically reconstructed projection images: comparison with digital breast tomosynthesis with full-field digital mammographic images.
PURPOSE To compare the performance of two versions of reconstructed two-dimensional ( 2D ) images in combination with digital breast tomo synthesis ( DBT ) versus the performance of st and ard full-field digital mammography ( FFDM ) plus DBT . MATERIAL S AND METHODS This trial had ethical committee approval , and all participants gave written informed consent . Examinations ( n = 24 901 ) in women between the ages of 50 and 69 years ( mean age , 59.2 years ) were interpreted prospect ively as part of a screening trial that included independent interpretations of FFDM plus DBT and reconstructed 2D images plus DBT . Reconstructed 2D images do not require radiation exposure . Using analyses for binary data that accounted for correlated interpretations and were adjusted for reader-specific volume , two versions ( initial and current ) of reconstructed 2D images used during trial periods 1 ( from November 22 , 2010 , to December 21 , 2011 ; 12 631 women ) and 2 ( from January 20 , 2012 , to December 19 , 2012 ; 12 270 women ) were compared in terms of cancer detection and false-positive rates with the corresponding FFDM plus DBT interpretations . RESULTS Cancer detection rates were 8.0 , 7.4 , 7.8 , and 7.7 per 1000 screening examinations for FFDM plus DBT in period 1 , initial reconstructed 2D images plus DBT in period 1 , FFDM plus DBT in period 2 , and current reconstructed 2D images plus DBT in period 2 , respectively . False-positive scores were 5.3 % , 4.6 % , 4.6 % , and 4.5 % , respectively . Corresponding reader-adjusted paired comparisons of false-positive scores revealed significant differences for period 1 ( P = .012 ) but not for period 2 ( ratio = 0.99 ; 95 % confidence interval : 0.88 , 1.11 ; P = .85 ) . CONCLUSION The combination of current reconstructed 2D images and DBT performed comparably to FFDM plus DBT and is adequate for routine clinical use when interpreting screening mammograms
For example , mammography screening does not seem to create anxiety in women who are given a clear result after a mammogram .
The incidence of breast cancer and mortality increases with age , and the GDG extrapolated that the absolute health benefits are greater in women aged 45 to 49 than those aged 40 to 44 years .
However , for the 45- to 49-year age group , the higher breast cancer incidence and mortality compared with women between the ages of 40 and 44 , as well as observational evidence showing a greater benefit in this age group ( 33 ) , led the GDG to judge that the balance of health effects probably favors screening , although the required re sources for screening likely differ across setting s ( 34 , 35 ) .
Other EtD criteria also were generally in favor of implementing organized mammography screening in this age group .
Despite intensified efforts by the European Council since 2003 , the implementation of organized , population -based mammography screening is not uniform across Europe and depends greatly on the policies in place in different countries , the organization of health care , and available re sources ( 1 ) .
Since the last edition of the European Guidelines on Breast Cancer Screening and Diagnosis was published in 2006 ( 2 ) , new evidence regarding breast cancer and innovation in guideline methodology prompted the European Commission Initiative on Breast Cancer ( ECIBC ) to develop new evidence -based recommendations ( in short , the European Breast Guidelines ) .
These guidelines inform women , health professionals , and policymakers about important questions related to organized mammography screening and breast cancer diagnosis , but recommendations may apply in context s in which organized screening programs are not in place .
Women generally consider these undesirable effects acceptable ( low certainty of evidence ) , and a systematic review suggested that women place a relatively low value on the psychosocial and physical effects of false-positive results and overdiagnosis ; however , some studies raised concerns about whether women fully underst and the result ing implication s ( 15 ) .
How Often Should Women Attend an Organized Mammography Screening Program ?