SIGNIFICANCE This study did not identify clear advantages of using the first generation of ormocer-based fillings rather than conventional composites .
OBJECTIVES In-vitro experiments on  ormocers ( ORganically MOdified CERamics )  have provided controversial results .
Consequently , the objectives of this meta- analysis were to ( 1 ) compare clinical performances of first generation ormocers versus conventional composite restorations  , ( 2 ) explore the influence of various clinical factors and the impact of the quality of studies on published results .
Restorations in abrasion/erosion cervical lesions: 8-year results of a triple blind randomized controlled trial.
PURPOSE An equivalence r and omized controlled trial within the subject was organized to evaluate the clinical long-term success of a new 2-step etch & rinse adhesive and a new nano-filled ormocer . METHODS 50 subjects , 21 males and 29 females aged between 21 and 65 , were r and omized to receive 150 restorations , 100 with the new restorative material , 50 with the composite as control , placed in non-carious cervical lesions with the same bonding system . The main outcome measure was the cause of failure at 8 years . R and omization was number table-generated , with allocation concealment by opaque sequentially numbered sealed and stapled envelopes . Subjects , examiner , and analyst were blinded to group assignment . Two interim analyses were performed . Data were analyzed by ANOVA and Cox test ( P < 0.05 ) . RESULTS After 8 years , 40 subjects and 120 teeth were included in the analysis of the primary outcome . There were eight failures in the experimental group and four failures in the control group . The cumulative loss rate was 7 % for both restorative material s , with the annual failure lower than 1 % , without any statistically significant difference . There were two key elements of failure : the presence of sclerotic dentin and the relationship between lesion and gingival margin
SIGNIFICANCE This study did not identify clear advantages of using the first generation of ormocer-based fillings rather than conventional composites .
OBJECTIVES In-vitro experiments on  ormocers ( ORganically MOdified CERamics )  have provided controversial results .
Consequently , the objectives of this meta- analysis were to ( 1 ) compare clinical performances of first generation ormocers versus conventional composite restorations  , ( 2 ) explore the influence of various clinical factors and the impact of the quality of studies on published results .