Bariatric surgery leads to marked and long-lasting weight reduction .
A large proportion of patients undergoing bariatric surgery have DM2 .
Glycemic control improves in the months after laparoscopic adjustable gastric b and ing , but it improves more rapidly and completely after laparoscopic Roux-en-Y gastric bypass surgery .
Thus , both types of surgery are capable of improving or even curing DM2 , but the mechanisms may differ
OBJECTIVE To systematic ally review the literature pertaining to the reversal of  type 2 diabetes mellitus ( DM2 ) after Roux-en-Y gastric bypass and adjustable gastric b and ing .
Factors associated with weight loss after gastric bypass.
BACKGROUND Gastric bypass ( GBP ) is the most common operation performed in the United States for morbid obesity . However , weight loss is poor in 10 % to 15 % of patients . We sought to determine the independent factors associated with poor weight loss after GBP . DESIGN Prospect i ve cohort study . We examined demographic , operative , and follow-up data by means of multivariate analysis . Variables investigated were age , sex , race , marital and insurance status , initial weight and body mass index ( BMI ) ( calculated as weight in kilograms divided by height in meters squared ) , comorbidities ( diabetes mellitus , hypertension , joint disease , sleep apnea , hyperlipidemia , and psychiatric disease ) , laparoscopic vs open surgery , gastric pouch area , gastrojejunostomy technique , and alimentary limb length . SETTING University tertiary referral center . PATIENTS All patients at our institution who underwent GBP from January 1 , 2003 , through July 30 , 2006 . MAIN OUTCOME MEASURES Weight loss at 12 months defined as poor ( < or = 40 % excess weight loss ) or good ( > 40 % excess weight loss ) . RESULTS Follow-up data at 12 months were available for 310 of the 361 patients ( 85.9 % ) undergoing GBP  during the study period . Mean preoperative BMI was 52 ( range , 36 - 108 ) . Mean BMI and excess weight loss at follow-up were 34 ( range , 17 - 74 ) and 60 % ( range , 8%-117 % ) , respectively . Thirty-eight patients ( 12.3 % ) had poor weight loss . Of the 4 variables associated with poor weight loss in the univariate analysis ( greater initial weight , diabetes , open approach , and larger pouch size ) , only diabetes ( odds ratio , 3.09 ; 95 % confidence interval , 1.35 - 7.09 [ P = .007 ] ) and larger pouch size ( odds ratio , 2.77;95 % confidence interval , 1.81 - 4.22 [ P < .001 ] ) remained after the multivariate analysis . CONCLUSIONS Gastric bypass results in substantial weight loss in most patients . Diabetes and larger pouch size are independently associated with poor weight loss after GBP
Bariatric surgery leads to marked and long-lasting weight reduction .
A large proportion of patients undergoing bariatric surgery have DM2 .
Glycemic control improves in the months after laparoscopic adjustable gastric b and ing , but it improves more rapidly and completely after laparoscopic Roux-en-Y gastric bypass surgery .
Thus , both types of surgery are capable of improving or even curing DM2 , but the mechanisms may differ
OBJECTIVE To systematic ally review the literature pertaining to the reversal of  type 2 diabetes mellitus ( DM2 ) after Roux-en-Y gastric bypass and adjustable gastric b and ing .