These results showed that AF is an independent risk factor for MI , CV death , and CV events
This study aim ed to investigate whether  atrial fibrillation ( AF ) predicts myocardial infa rct ion ( MI ) or cardiovascular ( CV ) death .
AF is a well-established risk factor for thrombotic stroke and all-cause mortality .
Acute myocardial infarction in patients with atrial fibrillation with a CHA2DS2-VASc score of 0 or 1: a nationwide cohort study.
BACKGROUND The risk of acute myocardial infa rct ion ( AMI ) in patients with atrial fibrillation ( AF ) with a CHA2DS2-VASc score of 0 ( for men ) or 1 ( for women ) has not been previously investigated . OBJECTIVE The objective of the present study was to compare the risk of AMI in AF and non-AF subjects with a low ( 0 or 1 ) CHA2DS2-VASc score . METHODS By using the National Health Insurance Research Data base in Taiwan , we identified 7254 men with AF ( with a CHA2DS2-VASc score of 0 ) and 4860 women with AF ( with a CHA2DS2-VASc score of 1 ) . For each study patient , 1 age- , sex- , and CHA2DS2-VASc score-matched subject  without AF was r and omly selected to constitute the control group ( n = 12,114 ) . The clinical end point was the occurrence of AMI . RESULTS During a mean follow-up period of 5.7 ± 3.6 years , 258 patients ( 1.1 % ) suffered an AMI , with an annual incidence of 0.29 % and 0.10 % for patients with and without AF . AF was an independent risk factor of AMI , with an adjusted hazard ratio ( HR ) of 2.93 ( 95 % confidence interval 2.21 - 3.87 ; P < .001 ) . The risk of AMI was higher in men with AF than in women with AF , with a hazard ratio of 2.24 ( 95 % confidence interval 1.61 - 3.11 ; P < .001 ) after adjustment for age and other comorbidities . CONCLUSION In patients with a CHA2DS2-VASc score of 0 or 1 , AF was an independent risk factor of AMI . The risk of AMI was higher in men with AF than in women with AF . Cardiovascular risk prevention should be performed as part of the holistic management of AF to minimize the risks of AMI associated with AF
These results showed that AF is an independent risk factor for MI , CV death , and CV events
This study aim ed to investigate whether  atrial fibrillation ( AF ) predicts myocardial infa rct ion ( MI ) or cardiovascular ( CV ) death .
AF is a well-established risk factor for thrombotic stroke and all-cause mortality .