Collectively , these outcomes support a volumetric dilution of vitamin D. The slopes of the respective regression lines , however , indicate a smaller increase in 25OHD than would be expected from a direct mobilization of stores into the circulation .
Hence , sequestration of 25OHD and its conversion to inactive metabolites would also play a role .
The purpose of this review was to confirm a volumetric dilution of vitamin D in obesity .
It was based on the hypothesis that weight loss , particularly fat loss , would increase serum 25-hydroxyvitamin D ( 25OHD ) in the obese .
Increased Consumption of Dairy Foods and Protein during Diet- and Exercise-Induced Weight Loss Promotes Fat Mass Loss and Lean Mass Gain in Overweight and Obese Premenopausal Women1234
Weight loss can have substantial health benefits for overweight or obese persons ; however , the ratio of fat : lean tissue loss may be more important . We aim ed to determine how daily exercise ( resistance and /or aerobic ) and a hypoenergetic diet varying in protein and calcium content from dairy foods would affect the composition of weight lost in otherwise healthy , premenopausal , overweight , and obese women . Ninety participants were r and omized to 3 groups ( n = 30/group ) : high protein , high dairy ( HPHD ) , adequate protein , medium dairy ( APMD ) , and adequate protein , low dairy ( APLD ) differing in the quantity of total dietary protein and dairy food- source protein consumed : 30 and 15 % , 15 and 7.5 % , or 15 and < 2 % of energy , respectively . Body composition was measured by DXA at 0 , 8 , and 16 wk and MRI ( n = 39 ) to assess visceral adipose tissue ( VAT ) volume at 0 and 16 wk . All groups lost body weight ( P < 0.05 ) and fat ( P < 0.01 ) ; however , fat loss during wk 8–16 was greater in the HPHD group than in the APMD and APLD groups ( P < 0.05 ) . The HPHD group gained lean tissue with a greater increase during 8–16 wk than the APMD group , which maintained lean mass and the APLD group , which lost lean mass ( P < 0.05 ) . The HPHD group also lost more VAT as assessed by MRI ( P < 0.05 ) and trunk fat as assessed by DXA ( P < 0.005 ) than the APLD group . The reduction in VAT in all groups was correlated with intakes of calcium ( r = 0.40 ; P < 0.05 ) and protein ( r = 0.32 ; P < 0.05 ) . Therefore , diet- and exercise-induced weight loss with higher protein and increased dairy product intakes promotes more favorable body composition changes in women characterized by greater total and visceral fat loss and lean mass gain
Collectively , these outcomes support a volumetric dilution of vitamin D. The slopes of the respective regression lines , however , indicate a smaller increase in 25OHD than would be expected from a direct mobilization of stores into the circulation .
Hence , sequestration of 25OHD and its conversion to inactive metabolites would also play a role .
The purpose of this review was to confirm a volumetric dilution of vitamin D in obesity .
It was based on the hypothesis that weight loss , particularly fat loss , would increase serum 25-hydroxyvitamin D ( 25OHD ) in the obese .