Conclusion Various methods have been used at all stages of CSPBM development .
The choice between developing a classification system de novo or from an existing instrument may depend on the availability of a suitable existing measure , while the choice between a decomposed or composite approach appears to be determined primarily by the purpose for which the instrument is design ed .
Background Health state utility values ( HSUVs ) are required to calculate quality -adjusted life-years ( QALYs ) .
They are frequently derived from generic preference-based measures of health .
However , such generic measures may not capture health attributes of relevance to specific conditions .
In such cases , a condition-specific preference-based measure ( CSPBM ) may be more appropriate .
Objective This systematic review aim ed to identify all published accounts of developing CSPBMs to describe and appraise the methods used .
Estimating a preference-based single index from the Overactive Bladder Questionnaire.
OBJECTIVES The aim of the study is to estimate a preference-based single index for calculating quality -adjusted life years for patients with overactive bladder ( OAB ) , based on a survey of the UK general population using the 5-dimensional health classification system OAB-5D , derived from the vali date d Overactive Bladder Question naire ( OAB-q ) . METHODS An interview valuation survey of members of public in the South Yorkshire , UK was undertaken using the time-trade-off method . Each respondent was r and omly allocated to one of 14 blocks , and valued seven states each plus the " pits " state , so that a total of 99 states were valued . A number of multivariate regression models were estimated for predicting a total of 3125 health state values defined by the classification . Models were compared and selected using a set of criteria , including overall diagnosis by adjusted R-squared , the sign and significance of individual parameter estimates , the relative size of coefficients within a given dimension and predictive ability . RESULTS The mean model was recommended for use in economic evaluation . CONCLUSION This will permit the cost-effectiveness of new interventions to be assessed in patients with OAB using existing and future OAB-q data sets
Conclusion Various methods have been used at all stages of CSPBM development .
The choice between developing a classification system de novo or from an existing instrument may depend on the availability of a suitable existing measure , while the choice between a decomposed or composite approach appears to be determined primarily by the purpose for which the instrument is design ed .
Background Health state utility values ( HSUVs ) are required to calculate quality -adjusted life-years ( QALYs ) .
They are frequently derived from generic preference-based measures of health .
However , such generic measures may not capture health attributes of relevance to specific conditions .
In such cases , a condition-specific preference-based measure ( CSPBM ) may be more appropriate .
Objective This systematic review aim ed to identify all published accounts of developing CSPBMs to describe and appraise the methods used .