Synthesized evidence indicates that addition of multiple micronutrients to Fe supplementation may only marginally improve Hb response compared with Fe supplementation alone .
However , addition of ' other micronutrients ' may have a negative effect .
Routine addition of unselected multiple micronutrients to Fe therefore appears unjustified for nutritional anaemia control programmes
OBJECTIVES To study the effect of combining multiple ( two or more ) micronutrients with Fe supplementation on Hb response , when compared with placebo and with Fe supplementation , in children .
Nutritional efficacy of a fortified weaning rusk in a rural area near Beijing.
A micronutrient-fortified rusk for weanling children was tested in a rural area near Beijing . Two hundred twenty-six children aged 6 - 13 mo were r and omly assigned by village to either a micronutrient-fortified or an unfortified rusk , daily for 3 mo . The fortified rusk contained extra zinc ; iron ; calcium ; vitamins A , D , and B-12 ; thiamin , riboflavin , niacin , and folic acid . Infants receiving the fortified rusk exhibited no decline in hemoglobin concentrations during the study whereas those receiving the unfortified rusk exhibited a significant decline . Improvements were also seen in erythrocyte porphyrin , plasma vitamin A , and riboflavin status , but these improvements were seen in both of the groups . Micronutrient fortification was probably beneficial for iron status and the fortified rusk promises to be an effective vehicle for supplementation
Synthesized evidence indicates that addition of multiple micronutrients to Fe supplementation may only marginally improve Hb response compared with Fe supplementation alone .
However , addition of ' other micronutrients ' may have a negative effect .
Routine addition of unselected multiple micronutrients to Fe therefore appears unjustified for nutritional anaemia control programmes
OBJECTIVES To study the effect of combining multiple ( two or more ) micronutrients with Fe supplementation on Hb response , when compared with placebo and with Fe supplementation , in children .