Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .
Breast-feeding, maternal IgE, and total serum IgE in childhood.
BACKGROUND There is controversy regarding the relationship of the effect of breast-feeding on markers of allergy such as total serum IgE in childhood . OBJECTIVE This study , using longitudinal data , tested the hypothesis that the relation of breast-feeding to IgE in childhood differs depending on maternal total IgE level . METHODS Total serum IgE was assessed with the paper radioimmunosorbent test at 4 ages in nonselected children enrolled at birth into the prospect i ve Tucson Children 's Respiratory Study . Children were classified as never breast-fed , breast-fed less than 4 months , or breast-fed 4 months or longer , on the basis of physician report or question naires completed by parents by the time the child was 18 months old . A longitudinal r and om effects model was used to test for group differences and temporal trends in IgE for children classified with reference to maternal IgE ( high tertile vs all others ) and breast-feeding history . A total of 664 children with 1457 observations were included . RESULTS Among children whose mothers were in the 2 lower tertiles of IgE , breast-feeding was associated with lower total serum IgE at age 6 years ( 24.2 vs 44.3 IU/mL for never breast-fed children ; P < .02 ) ; similar trends existed at age 11 years . In contrast , for children whose mothers were in the highest tertile of IgE , breast-feeding of 4 months or longer was associated with higher IgE levels in the child compared with those never breast-fed or breast-fed less than 4 months ( 97.0 vs 38.9 IU/mL ; P < . 005 ) . These cross-sectional analyses were confirmed with the longitudinal r and om effects model , which also showed no effect of confounders . Paternal IgE showed no similar relation with child IgE. CONCLUSION Breast-feeding appears to have paradoxic relations with IgE in childhood , depending on maternal IgE level . These findings may help explain the contradictory results found in other investigations of the relation of breast-feeding to allergic symptoms and markers
Feeding soya-based formula as opposed to st and ard cow 's milk formula did not reduce the risk of having asthma or wheeze at any age .
In infants with at least one first degree relative with atopy , hydrolysed formula for a minimum of 4 months combined with dietary restrictions and environment measures may reduce the risk of developing asthma or wheeze in the first year of life .
There is insufficient evidence to suggest that soya-based milk formula has any benefit
BACKGROUND In infants with a family history of atopy , food allergen avoidance has been advocated as means of preventing the development of atopic disease when breast-feeding is not possible or supplemental feeding is needed .
Most infant formulas are based on cow 's milk protein .
Alternative choices include soya based and hydrolysed cows milk formulas .
OBJECTIVES To estimate the effect of dietary avoidance of cow 's milk protein on the development of asthma or wheeze in children .