Current evidence is supportive of recommending probiotics for the management of halitosis .
Based on this review , transient ( average of 2 weeks ) dosing with probiotics ( mainly Lactobacillus strains ) has a moderate effect on halitosis regarding OLT scores , but we could not confirm the effects of probiotics on the VSC reduction .
Although several studies have evaluated the inhibitory effect of  probiotics  on  halitosis  , findings are inconsistent .
This systematic review and meta- analysis of r and omized clinical trials ( RCT ) was conducted to summarize the evidence on the effect of  probiotics on halitosis .
Multi-Sensor Approach for the Monitoring of Halitosis Treatment via Lactobacillus brevis (CD2)—Containing Lozenges—A Randomized, Double-Blind Placebo-Controlled Clinical Trial
The aim of this r and omized clinical trial was to evaluate whether a recently described multi-sensor approach called BIONOTE ® is accurate enough to verify the efficacy of treatment of patients with halitosis . A treatment with Lactobacillus brevis (CD2)–containing lozenges , compared with placebo was tested . The BIONOTE ® was compared with traditional techniques used to detect halitosis : OralChroma ™ and two calibrated odor judges enrolled for the organoleptic assessment s. Twenty patients ( 10 treated and 10 placebo ) , suffering from active phase halitosis were included in the study . Treatment consisted of Lactobacillus brevis (CD2)—containing lozenges or placebo , 4 tablets/day for 14 days . t0 was before the beginning of the study ; t1 was day 7 and t2 was day 14 . The effectiveness of treatment was assessed through : ( 1 ) Rosenberg score ; ( 2 ) Winkel tongue coating index ( WTCI ) anterior and posterior ; ( 2 ) OralChroma ™ ; ( 3 ) the new developed multi-sensor approach , called BIONOTE ® ( test technique ) . Only the WTCI anterior revealed statistically significant changes between t0 and t2 data ( p = 0.014 ) in the treated group . Except for the WTCI anterior , all diagnostic methods revealed the lack of effectiveness for halitosis of a 14-days treatment with Lactobacillus brevis (CD2)–containing lozenges . The BIONOTE ® multisensor system seems accurate in addition to OralChroma ™ to assess the initial condition of halitosis and its mitigation during treatment
Current evidence is supportive of recommending probiotics for the management of halitosis .
Based on this review , transient ( average of 2 weeks ) dosing with probiotics ( mainly Lactobacillus strains ) has a moderate effect on halitosis regarding OLT scores , but we could not confirm the effects of probiotics on the VSC reduction .
Although several studies have evaluated the inhibitory effect of  probiotics  on  halitosis  , findings are inconsistent .
This systematic review and meta- analysis of r and omized clinical trials ( RCT ) was conducted to summarize the evidence on the effect of  probiotics on halitosis .