Other parameters under investigation were not affected by either low or high glycaemic indices .
The present systematic review and meta- analysis provides evidence of a beneficial effect of a low glycaemic index/load diet in children and adolescents being either overweight or obese .
The objective of the present systematic review and meta- analysis was to synthesize the available literature data investigating the effects of low glycaemic index/low glycamic load dietary regimens on anthropometric parameters , blood lipid profiles , and indicators of glucose metabolism in children and adolescents .
Development of a prediction equation for insulin sensitivity from anthropometry and fasting insulin in prepubertal and early pubertal children.
OBJECTIVE To test the utility of homeostasis model assessment ( HOMA ) in predicting insulin sensitivity [ x10(- 4 ) min(-1)/(microIU/ml ) ] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasting insulin . RESEARCH DESIGN AND METHODS We studied 156 white and African-American children with complete data ( mean age 9.7 + /- 1.8 years , 87.8 % Tanner Stage 1 or 2 ) . For development of new equations , two-thirds of the children were r and omly assigned to a development group , whereas the remaining children were assigned to a cross-validation group . RESULTS A modified HOMA equation accurately predicted insulin sensitivity , but its utility is similar to fasting insulin alone . Demographic and anthropometric measures alone did not predict insulin sensitivity accurately , even when precise measures of body composition were included in the prediction model . Ethnicity , calf skinfold , and fasting insulin together explained 73 % of the variance in insulin sensitivity and accurately predicted insulin sensitivity . The regression of measured versus predicted insulin sensitivity in the cross-validation group was not significantly different from the line of identity ( P > 0.05 ) . Mean difference between measured and predicted insulin sensitivity was also not significant ( P > 0.05 ) . Some bias was apparent , particularly in white boys . CONCLUSIONS Ethnicity , calf skinfold , and fasting insulin can accurately predict insulin sensitivity with greater precision than HOMA or fasting insulin alone ( R(2 ) = 0.73 ) . Future studies , however , are needed to examine whether a universal equation is possible . A cross-vali date d prediction equation may be useful in population -based studies when complex measures of insulin sensitivity are not available
Other parameters under investigation were not affected by either low or high glycaemic indices .
The present systematic review and meta- analysis provides evidence of a beneficial effect of a low glycaemic index/load diet in children and adolescents being either overweight or obese .
The objective of the present systematic review and meta- analysis was to synthesize the available literature data investigating the effects of low glycaemic index/low glycamic load dietary regimens on anthropometric parameters , blood lipid profiles , and indicators of glucose metabolism in children and adolescents .