And rogen rise is greater in those patients who lose more weight as well as in younger , non-diabetic subjects with a greater degree of obesity .
Body weight loss is also associated with a decrease in estradiol and an increase in gonadotropins levels .
These data show that weight loss is associated with an increase in both bound and unbound testosterone levels .
The normalization of sex hormones induced by body weight loss is a possible mechanism contributing to the beneficial effects of surgery in morbid obesity
OBJECTIVE Few r and omized clinical studies have evaluated the impact of diet and physical activity on testosterone levels in obese men with conflicting results .
Conversely , studies on bariatric surgery in men generally have shown an increase in testosterone levels .
The aim of this study is to perform a systematic review and meta- analysis of available trials on the effect of body weight loss on sex hormones levels .
Body composition and hormonal responses to a carbohydrate-restricted diet.
The few studies that have examined body composition after a carbohydrate-restricted diet have reported enhanced fat loss and preservation of lean body mass in obese individuals . The role of hormones in mediating this response is unclear . We examined the effects of a 6-week carbohydrate-restricted diet on total and regional body composition and the relationships with fasting hormone concentrations . Twelve healthy normal-weight men switched from their habitual diet ( 48 % carbohydrate ) to a carbohydrate-restricted diet ( 8 % carbohydrate ) for 6 weeks and 8 men served as controls , consuming their normal diet . Subjects were encouraged to consume adequate dietary energy to maintain body mass during the intervention . Total and regional body composition and fasting blood sample s were assessed at weeks 0 , 3 , and 6 of the experimental period . Fat mass was significantly ( P < or=.05 ) decreased ( -3.4 kg ) and lean body mass significantly increased ( + 1.1 kg ) at week 6 . There was a significant decrease in serum insulin ( -34 % ) , and an increase in total thyroxine ( T(4 ) ) ( + 11 % ) and the free T(4 ) index ( + 13 % ) . Approximately 70 % of the variability in fat loss on the carbohydrate-restricted diet was accounted for by the decrease in serum insulin concentrations . There were no significant changes in glucagon , total or free testosterone , sex hormone binding globulin ( SHBG ) , insulin-like growth factor-I ( IGF-I ) , cortisol , or triiodothyronine ( T(3 ) ) uptake , nor were there significant changes in body composition or hormones in the control group . Thus , we conclude that a carbohydrate-restricted diet result ed in a significant reduction in fat mass and a concomitant increase in lean body mass in normal-weight men , which may be partially mediated by the reduction in circulating insulin concentrations
And rogen rise is greater in those patients who lose more weight as well as in younger , non-diabetic subjects with a greater degree of obesity .
Body weight loss is also associated with a decrease in estradiol and an increase in gonadotropins levels .
These data show that weight loss is associated with an increase in both bound and unbound testosterone levels .
The normalization of sex hormones induced by body weight loss is a possible mechanism contributing to the beneficial effects of surgery in morbid obesity
OBJECTIVE Few r and omized clinical studies have evaluated the impact of diet and physical activity on testosterone levels in obese men with conflicting results .
Conversely , studies on bariatric surgery in men generally have shown an increase in testosterone levels .
The aim of this study is to perform a systematic review and meta- analysis of available trials on the effect of body weight loss on sex hormones levels .