T2D prevention by physical activity or diet or both proved cost-effective according to accepted thresholds , except for five inconclusive studies , three on diabetes prevention and two on obesity control .
This confirms that lifestyle interventions for the primary prevention of diabetes are cost-effective .
To summarize key findings of economic evaluations of lifestyle interventions for the primary prevention of  type 2 diabetes ( T2D ) in high-risk subjects .
Cost-effectiveness of an exercise program during pregnancy to prevent gestational diabetes: Results of an economic evaluation alongside a randomised controlled trial
Background The prevalence of gestational diabetes mellitus ( GDM ) is increasing worldwide . GDM and the risks associated with GDM lead to increased health care costs and losses in productivity . The objective of this study is to evaluate whether the FitFor2 exercise program during pregnancy is cost-effective from a societal perspective as compared to st and ard care . Methods A r and omised controlled trial ( RCT ) and simultaneous economic evaluation of the FitFor2 program were conducted . Pregnant women at risk for GDM were r and omised to an exercise program to prevent high maternal blood glucose ( n = 62 ) or to  st and ard care  ( n = 59 ) . The exercise program consisted of two sessions of aerobic and strengthening exercises per week . Clinical outcome measures were maternal fasting blood glucose levels , insulin sensitivity and infant birth weight . Quality of life was measured using the EuroQol 5-D and quality -adjusted life-years ( QALYs ) were calculated . Re source utilization and sick leave data were collected by question naires . Data were analysed according to the intention-to-treat principle . Missing data were imputed using multiple imputations . Bootstrapping techniques estimated the uncertainty surrounding the cost differences and incremental cost-effectiveness ratios . Results There were no statistically significant differences in any outcome measure . During pregnancy , total health care costs and costs of productivity losses were statistically non-significant ( mean difference € 1308 ; 95%CI € -229 - € 3204 ) . The cost-effectiveness analyses showed that the exercise program was not cost-effective in comparison to the control group for blood glucose levels , insulin sensitivity , infant birth weight or QALYs . Conclusion The twice-weekly exercise program for pregnant women at risk for GDM evaluated in the present study was not cost-effective compared to st and ard care . Based on these results , implementation of this exercise program for the prevention of GDM can not be recommended . Trial registration
T2D prevention by physical activity or diet or both proved cost-effective according to accepted thresholds , except for five inconclusive studies , three on diabetes prevention and two on obesity control .
This confirms that lifestyle interventions for the primary prevention of diabetes are cost-effective .
To summarize key findings of economic evaluations of lifestyle interventions for the primary prevention of  type 2 diabetes ( T2D ) in high-risk subjects .