The pooled estimate of efficacy of lactobacillus rhamnosus GG and other probiotics significantly reduced the duration of diarrhea .
In conclusion , probiotics exert positive effect in reducing the duration of acute rotavirus diarrhea  compared with control
BACKGROUND Probiotic therapies with different strains demonstrated some beneficial effects , although some studies did not show any significant effects .
This study assessed systematic ally the current knowledge on the effect of probiotic bacteria on duration of  acute rotavirus diarrhea in children compared with control .
Probiotics in the treatment of acute rotavirus diarrhoea. A randomized, double-blind, controlled trial using two different probiotic preparations in Bolivian children
Background Evidence suggests that probiotics reduce  rotavirus diarrhoea duration . Although there are several probiotic strains potentially useful , daily practice is often limited by the type and number of products locally available . In general , information about combined products is scarce . In this study we compare the effect of two probiotic products in the treatment of diarrhoea in children less than 2 years of age . Methods A R and omized double-blind controlled clinical trial in children hospitalized for acute rotavirus diarrhoea , in the Paediatric Centre Albina Patino , Cochabamba , Bolivia . Participants were children aged 1 - 23 months , who were r and omly assigned to receive one of three treatments : Oral rehydration therapy plus placebo ; Oral rehydration solution plus Saccharomyces boulardii ; or Oral rehydration solution plus a compound containing Lactobacillus acidophilus , Lactobacillus rhamnosus , Bifidobacterium longum and Saccharomyces boulardii . Sample size was 20 per group and the outcomes were duration of diarrhoea , of fever , of vomiting and of hospitalization . Results 64 cases finished the protocol . On admission , patients ' characteristics were similar . Median duration of diarrhoea ( p = 0.04 ) in children who received the single species product ( 58 hours ) was shorter than in controls ( 84.5 hrs ) . Comparing children that received the single probiotic product and controls showed shorter duration of fever ( 18 vs 67 hrs ) ( p = 0.0042 ) and the mixed probiotic of vomiting ( 0 vs 42.5 hrs ) ( p = 0.041 ) . There was no effect on duration of hospitalization ( p = 0.31 ) . When experimental groups were merged , statistical significance of changes increased ( total duration of diarrhoea , fever and vomiting P = 0.025 , P = 0.025 and P = 0.014 , respectively ) . Conclusions Both products decreased the duration of diarrhoea compared to oral rehydration solution alone . This decrease was significant only for the single species product which also decreased the duration of fever . With the multiple species product there was no vomiting subsequent to the initiation of treatment . The quantity of probiotic bacteria needed for optimum treatment of gastroenteritis remains to be determined , particularly when multiple species are included in the product . Trial Registration Clinical Trials ( NCT ) :
The pooled estimate of efficacy of lactobacillus rhamnosus GG and other probiotics significantly reduced the duration of diarrhea .
In conclusion , probiotics exert positive effect in reducing the duration of acute rotavirus diarrhea  compared with control
BACKGROUND Probiotic therapies with different strains demonstrated some beneficial effects , although some studies did not show any significant effects .
This study assessed systematic ally the current knowledge on the effect of probiotic bacteria on duration of  acute rotavirus diarrhea in children compared with control .