Moreover , subgroup analyses suggested that the effects of glycemic control were significantly influenced by the sex of the subjects and the type and the method of intake of ITF .
Conclusions Our analyses confirmed that these four main glycemic indicators were significantly reduced by ITF supplementation , particularly in the prediabetes and T2DM population .
Evidence supports that reasonable administration of ITF supplementation may have potential clinical value as an adjuvant therapy for prediabetes and T2DM management .
Background Currently , many clinical trials have shown that inulin-type fructans ( ITF ) supplementation is associated with glycemic control ; nevertheless , the results are inconclusive .
The aim of this meta- analysis of r and omized controlled trials was to assess the effects of ITF supplementation on glycemic control .
The effects of a diet rich in inulin or wheat fibre on markers of cardiovascular disease in overweight male subjects.
BACKGROUND Previous studies suggest that the beneficial health effects of a diet rich in whole grains could be a result of the individual fibres found in the grain . The present study aim ed to investigate the influence of a diet high in either wheat fibre ( as an example of an insoluble fibre ) or inulin ( a nondigestible carbohydrate ) on markers of cardiovascular disease . METHODS Ten male participants classified as at higher risk of cardiovascular disease [ mean ( SD ) body mass index 30.2 ( 3 ) kg m(-2 ) , mean ( SD ) waist circumference 106.4 ( 7 ) cm , mean ( SD ) age 39.8 ( 9 ) years ] were recruited to a r and omised , controlled , cross-over study comparing the consumption of bespoke bread rolls containing either inulin , wheat germ or refined grain ( control ) ( 15 g day(-1 ) ) for 4 weeks with a 4-week washout period between each regime . At the end of each regime , participants underwent an oral glucose tolerance test ( OGTT ) , measures of pulse wave velocity ( PWV ) , 24-h ambulatory blood pressure ( AMBP ) , plasma lipid status and markers of glucose control . RESULTS There was no difference in measures of glucose control , lipid status , 24-h AMBP or PWV after the intervention periods and no changes compared to baseline . There was no significant difference between OGTT glucose and insulin time profiles ; however , there was a significant difference in area under the curves between the wheat fibre and control interventions when comparing change from baseline ( control + 10.2 % , inulin + 4.3 % , wheat fibre -2.5 % ; P = 0.03 ) . CONCLUSIONS Only limited differences between the interventions were identified , perhaps as a consequence of the amount of fibre used and intervention length . The wheat germ intervention result ed in a significant reduction in glucose area under the curve , suggesting that this fibre may aid glucose control
Moreover , subgroup analyses suggested that the effects of glycemic control were significantly influenced by the sex of the subjects and the type and the method of intake of ITF .
Conclusions Our analyses confirmed that these four main glycemic indicators were significantly reduced by ITF supplementation , particularly in the prediabetes and T2DM population .
Evidence supports that reasonable administration of ITF supplementation may have potential clinical value as an adjuvant therapy for prediabetes and T2DM management .
Background Currently , many clinical trials have shown that inulin-type fructans ( ITF ) supplementation is associated with glycemic control ; nevertheless , the results are inconclusive .
The aim of this meta- analysis of r and omized controlled trials was to assess the effects of ITF supplementation on glycemic control .