Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .
Effect of garlic (Allium sativum) powder tablets on serum lipids, blood pressure and arterial stiffness in normo-lipidaemic volunteers: a randomised, double-blind, placebo-controlled trial.
Recent studies have cast doubt on the proposed lipid-lowering and blood pressure-lowering effects of garlic . We tested the effect of dried garlic ( Allium sativum ) powder on blood lipids , blood pressure and arterial stiffness in a 12-week r and omised , double-blind , placebo-controlled trial . Seventy-five healthy , normo-lipidaemic volunteers ( men and women aged 40 - 60 years ) were assigned to dried garlic powder tablets ( 10.8 mg alliin ( 3-(2-propenylsulfinyl)-L-alanine)/d , corresponding to about three garlic cloves ) or placebo .  Sixty-two subjects were eligible for the per- protocol analysis . The primary outcome measure was serum total cholesterol concentration . Secondary outcome measures were LDL-cholesterol , HDL-cholesterol and triacylglycerol concentrations , blood pressure and arterial stiffness ( assessed by pulse wave velocity ) . No significant differences between the garlic and placebo groups were detected for any of the outcome measures . However , garlic powder was associated with a near-significant decrease ( 12 % ) in triacylglycerol concentration ( P=0.07 ) . In conclusion , garlic powder tablets have no clinical ly relevant lipid-lowering and blood pressure-lowering effects in middle-aged , normo-lipidaemic individuals . The putative anti-atherosclerotic effect of garlic may be linked to risk markers other than blood lipids
Garlic reduces TC to a modest extent , an effect driven mostly by the modest reductions in TAG , without appreciable LDL lowering or HDL elevation .
Higher baseline line TC levels and the use of dietary modification may alter the effect of garlic on these parameters .
In order to determine the impact of  garlic on total cholesterol ( TC ) , TAG levels , as well as LDL and HDL  , and establish if any variables have an impact on the magnitude of this effect , a meta- analysis was conducted .