For common outcomes there was similar efficacy between PDE-5 inhibitors
Background There are no r and omised and properly blinded trials directly comparing one PDE-5 inhibitor with another in a normal home setting .
Valid indirect comparisons with a common comparator must examine equivalent doses , similar duration , similar population s , with the same outcomes reported in the same way .
Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erectile dysfunction.
This r and omised , double-blind study assessed the long-term efficacy and tolerability of vardenafil 10 and 20 mg in men with erectile dysfunction ( ED ) . A total of 566 men who completed an initial 12-month treatment period entered a 12-month extension . In these men , both doses of vardenafil produced improvement in scores for the ' erectile function ' Domain of the International Index of Erectile Function , evident from week 4 and maintained through 2 years . Sexual Encounter Profile diary responses indicated that following treatment , penetration was achieved on 92 - 94 % of attempts and erections that lasted long enough for successful intercourse were achieved on 87 - 89 % of attempts . In response to the General Assessment Question , 90 - 92 % of patients reported improved erections with vardenafil . Most treatment-emergent events were mild and transient with no cardiovascular safety concerns . These results support the long-term efficacy , reliability and tolerability of vardenafil 10 and 20 mg in men with ED
For common outcomes there was similar efficacy between PDE-5 inhibitors
Background There are no r and omised and properly blinded trials directly comparing one PDE-5 inhibitor with another in a normal home setting .
Valid indirect comparisons with a common comparator must examine equivalent doses , similar duration , similar population s , with the same outcomes reported in the same way .