This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
The Effects of Vitamin D Supplementation on Glucose Control and Insulin Resistance in Patients with Diabetes Type 2: A Randomized Clinical Trial Study
Background : Vitamin D deficiency is prevalent in diabetes type 2 and this vitamin may be related to insulin action . This r and omized controlled trial study was done to evaluate the effect of vitamin D supplementation on glucose control and insulin resistance in patients with diabetes type 2 . Methods : Participants of this r and omized clinical trial study consisted of 28 patients with type 2 diabetes who received 100 microgram ( 4000 IU ) vitamin D and 30 diabetic patients who received placebo for 2 months between September 2012 and February 2013 . The effect of vitamin D on glucose control was assessed by measuring HbA1c and insulin resistance as HOMA-IR at the baseline and the end of the intervention . Results : The results showed a significant decrease in HbA1c ( from 7.29 ± 0.22 % to 6.76 ± 0.18 % , P<0.001 ) and insulin concentration ( from 8.24 ± 0.97 μIU/mL to 6.55 ± 0.28 μIU/mL , P=0.048 ) , but a non-significant decrease in HOMA-IR  in vitamin D  group . Also , HDL-C level increased significantly in both of vitamin D ( P=0.046 ) and placebo groups ( P=0.028 ) . Conclusion : It seems that vitamin D supplementation has beneficial effects on glucose homeostasis and can increases insulin sensitivity in diabetic 2 patients
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .