There were no overall effects from antioxidant vitamins , inositol or dietary minerals on psychiatric symptoms .
There is preliminary evidence that certain vitamin and mineral supplements may reduce psychiatric symptoms in some people with schizophrenia .
BACKGROUND When used as an adjunctive with antipsychotics , certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia , by restoring nutritional deficits , reducing oxidative stress , or modulating neurological pathways .
CSF inositol in schizophrenia and high-dose inositol treatment of schizophrenia
Inositol is a key metabolite in the phosphatidylinositol cycle , which is a second messenger system for serotonin-2 receptors that have been implicated in the pathophysiology of schizophrenia . Cerebrospinal fluid inositol levels were measured in 20 schizophrenic patients and 19 age- and sex-matched controls and no difference was found . However , the patients were all neuroleptic-treated . A controlled double-blind crossover trial of 12 g daily of inositol for a month in 12 anergic schizophrenic patients , twice the dose given before in schizophrenia , did not show any beneficial effects . However , the number of patients studied was small and the length of time of inositol administration may not have been sufficient
There were no overall effects from antioxidant vitamins , inositol or dietary minerals on psychiatric symptoms .
There is preliminary evidence that certain vitamin and mineral supplements may reduce psychiatric symptoms in some people with schizophrenia .
BACKGROUND When used as an adjunctive with antipsychotics , certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia , by restoring nutritional deficits , reducing oxidative stress , or modulating neurological pathways .