In comparison with the baseline , NNS consumption was not found to increase blood glucose level , and its concentration gradually declined over the course of observation following NNS consumption .
The glycemic impact of NNS consumption did not differ by type of NNS but to some extent varied by participants ’ age , body weight , and diabetic status .
Conclusions NNS consumption was not found to elevate blood glucose level .
Background / objectives Nonnutritive sweeteners ( NNSs ) are zero- or low-calorie alternatives to nutritive sweeteners , such as table sugars .
A systematic review and meta- analysis of r and omized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of NNSs .
Consumption of Low-Calorie Sweeteners among Children and Adults in the United States.
BACKGROUND Consumption of low-calorie sweeteners ( LCSs ) has increased markedly during the past several decades , yet the prevalence of LCS consumption in recent years is currently unknown . OBJECTIVE The aim of this study was to describe LCS consumption in the United States and to characterize consumption by sociodemographic subgroups , source , frequency , eating occasion , and location . DESIGN Cross-sectional study using National Health and Nutrition Examination Survey data from 2009 to 2012 . The prevalence of LCS consumption was assessed using two 24-hour dietary recalls , while the frequency ( number of times per day ) , occasion ( meal vs snack vs alone ) , and location of LCS consumption ( at home vs away from home ) was assessed using data from the one , in-person , 24-hour dietary recall . PARTICIPANTS National Health and Nutrition Examination Survey participants ( 2 years old or older ) either in 2009 - 2010 ( n=9,047 ) or in 2011 - 2012 ( n=7,939 ) . After excluding participants with implausible energy intake ( n=44 ) , the final sample size was 16,942 . MAIN OUTCOME MEASURES The primary outcome was the proportion of individuals consuming one or more foods , beverages , or packets containing LCSs  during at least one of their two dietary recalls . STATISTICAL ANALYSES PERFORMED Data were weighted to provide national estimates and Stata frequency procedures for complex survey design were used for all analyses . RESULTS Our findings were that 25.1 % of children and 41.4 % adults reported consuming LCSs . Most LCS consumers reported use once daily ( 80 % of children , 56 % of adults ) and frequency of consumption increased with body weight in adults . LCS consumption was higher in females compared with males among adults , and in obese individuals , compared with overweight and normal-weight individuals . Individuals of non-Hispanic white race/ethnicity also had higher prevalence of consumption compared with non-Hispanic blacks and Hispanics and those in the highest tertile of income had higher LCS consumption compared with individuals of middle or low income across LCS product categories in adults , and for LCS beverages and LCS foods in children . Most LCS consumers reported consuming  LCS  with meals ( 64 % of adults , 62 % of children ) and the majority of LCS consumption occurred at home ( 71 % and 72 % among adults and children , respectively ) . CONCLUSIONS LCS consumption is highly prevalent in the United States , among both children and adults . Well-controlled , prospect i ve trials are required to underst and the health impact of this widespread LCS exposure
In comparison with the baseline , NNS consumption was not found to increase blood glucose level , and its concentration gradually declined over the course of observation following NNS consumption .
The glycemic impact of NNS consumption did not differ by type of NNS but to some extent varied by participants ’ age , body weight , and diabetic status .
Conclusions NNS consumption was not found to elevate blood glucose level .
Background / objectives Nonnutritive sweeteners ( NNSs ) are zero- or low-calorie alternatives to nutritive sweeteners , such as table sugars .
A systematic review and meta- analysis of r and omized controlled trials was conducted to quantitatively synthesize existing scientific evidence on the glycemic impact of NNSs .