Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .
Effects of caregivers' perceived stigma and causal beliefs on patients' adherence to antidepressant treatment.
OBJECTIVE Nonadherence to prescribed medications is a significant problem in the treatment of mood disorders . Previously proposed adherence models have not been sufficiently accurate in identifying patients who do not adhere to treatment . This study evaluated the importance of the social context in adherence by using a prospect i ve , longitudinal analysis . Specifically , this study evaluated the effects of caregivers ' causal beliefs about depression and their perceptions of stigma on three-month treatment adherence among patients with depression . METHODS Fifty patients with major depressive disorder and their primary caregivers were identified at a psychiatric hospital 's outpatient clinic .  Attributions for the causes of depression ( either cognitive and attitudinal or medical and biological ) and perceived stigma were assessed among caregivers at baseline , and patients ' adherence was evaluated three-months after treatment began . RESULTS Data were available for 47 patients at follow-up . Caregivers ' attribution of depression to cognitive and attitudinal problems significantly predicted patients ' decreased adherence . However , the degree of patients ' adherence was not predicted by caregivers ' attributions to medical and biological causes and caregivers ' perceived stigma . CONCLUSIONS The findings stress the importance of patients ' social environment in determining treatment adherence and the necessity of educating caregivers about the impact that their causal attributions have on patients ' behavior . Involving caregivers in treatment may improve their attitude toward patients with depression and , in doing so , enhance patients ' adherence and outcome
Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .