The DASH dietary pattern may lead to an improvement in insulin sensitivity independent of weight loss .
The DASH diet may play an important role in glycemic control in long- term interventions .
OBJECTIVE Type 2 diabetes is a major public health problem .
The Dietary Approaches to Stop Hypertension ( DASH ) eating pattern may contribute to managing risk factors of type 2 diabetes .
The objective of this study was to conduct a systematic review and meta- analysis on r and omized controlled trials ( RCTs ) that examine the effects of DASH diet consumption on the indices of glycemic control such as fasting blood glucose ( FBG ) , serum fasting insulin level , and Homeostatic Model Assessment insulin resistance ( HOMA-IR ) .
Hypocaloric high-protein diet improves glucose oxidation and spares lean body mass: comparison to hypocaloric high-carbohydrate diet.
The aim of the study was to investigate the effects of two hypocaloric ( 800-kcal ) diets on body weight reduction and composition , insulin sensitivity , and proteolysis in 25 normal glucose-tolerant obese women . The two diets had the following composition : 45 % protein , 35 % carbohydrate ( CHO ) , and 20 % fat ( HP diet , 10 subjects ) , and 60 % CHO , 20 % protein , and 20 % fat ( HC diet , 15 subjects ) ; both lasted 21 days . A euglycemic hyperinsulinemic ( 25 mU/kg/h ) clamp lasting 150 minutes combined with indirect calorimetry was performed before and after the diet . Both diets induced a similar decrease in body weight and fat mass ( FM ) , whereas fat-free mass ( FFM ) decreased only after the HC diet .  3-Methylhistidine ( 3-CH3-HIS ) excretion was reduced by 48 % after the HP diet and remained unchanged after the HC diet ( P < .05 ) . A significant correlation was found between the changes in FFM and in 3-CH3-HIS excretion after the diet ( rs = .50 , P < .02 ) . Blood glucose remained unchanged , while insulin decreased in both diets . Free fatty acids ( FFA ) significantly increased only after the HC diet ( P < .05 ) . During the clamp period , glucose disposal and glucose oxidation significantly increased after the HP diet and significantly decreased after the HC diet . Opposite results were found when measuring lipid oxidation . In conclusion , our experience suggests that ( 1 ) a hypocaloric diet providing a high percentage of natural protein can improve insulin sensitivity ; and ( 2 ) conversely , a hypocaloric high-polysaccharide-CHO diet decreases insulin sensitivity and is unable to spare muscle tissue
The DASH dietary pattern may lead to an improvement in insulin sensitivity independent of weight loss .
The DASH diet may play an important role in glycemic control in long- term interventions .
OBJECTIVE Type 2 diabetes is a major public health problem .
The Dietary Approaches to Stop Hypertension ( DASH ) eating pattern may contribute to managing risk factors of type 2 diabetes .
The objective of this study was to conduct a systematic review and meta- analysis on r and omized controlled trials ( RCTs ) that examine the effects of DASH diet consumption on the indices of glycemic control such as fasting blood glucose ( FBG ) , serum fasting insulin level , and Homeostatic Model Assessment insulin resistance ( HOMA-IR ) .