The review was registered ( Number CRD42013004632 ) on PROSPERO , the International Prospect i ve Register of Systematic Review s. Results The results indicated that PA is associated with significant and beneficial changes in fat percentage , waist circumference , systolic blood pressure , insulin , low-density lipoprotein cholesterol , and total cholesterol , as well as with small non-significant changes in diastolic blood pressure , glucose , and high-density lipoprotein cholesterol .
Conclusion Although limited , results from controlled trials suggest that PA intervention may improve physical fitness and risk factors for cardiovascular disease in adolescents who are overweight or obese
Background The increasing prevalence of obesity in the pediatric age range has become a major concern .
Studies have investigated the role of physical activity ( PA ) to prevent obesity in this population .
However , previous review s did not focus on the effects of PA in overweight/obese adolescents on physical fitness and risk factors for cardiovascular disease altogether .
Objective The present systematic review analyzed trials investigating the effect of PA on aerobic capacity , muscle strength , body composition , hemodynamic variables , biochemical markers , and endothelial function in obese/overweight adolescents .
Waist circumference is related to low-grade inflammation in youth.
OBJECTIVES To examine markers of inflammation in 9- and 15-year-olds with high waist circumference and compare these with controls , and to examine the relationships between inflammatory markers and cardiovascular disease ( CVD ) risk factors . METHODS Cross-sectional analysis of data from 2 299 Norwegian 9- and 15-year-olds participating in the " Physical activity among Norwegian Children Study " . In each sex and age group , the 10 participants with the highest waist circumference ( HW ) were selected ( n=40 ) for analyses , and a r and om sample of 40 participants within the same groups were included as controls . Inflammatory markers included C-reactive protein ( CRP ) , leptin , adiponectin , plasminogen activator inhibitor-1 ( PAI-1 ) , tumor necrosis factor-alpha ( TNF-alpha ) , hepatocyte growth factor ( HGF ) , resistin and interleukin-6 ( IL-6 ) . The CVD risk factors included blood pressure , glucose , insulin , triglycerides and high density lipoprotein cholesterol . RESULTS HW participants had elevated levels of CRP ( mean difference 1.50 mg/l ; 95 % confidence interval [ CI ] 0.33 to 2.66 ) , PAI-1 ( mean difference 13.3 ng/ml ; 95 % CI 4.1 to 22.5 ) and HGF ( mean difference 0.29 ng/ml ; 95 % CI 0.07 to 0.51 ) compared with controls . All CVD risk factors differed between the HW group and controls . The CVD risk factors were not associated with TNFalpha or IL-6 , but CRP , HGF and PAI-1 were related to the metabolic risk score . CONCLUSIONS Low grade systemic inflammation is already present in youth with high waist circumference . CRP , HGF and PAI-1 may be related to the adverse overall metabolic risk profile observed in these children and adolescents
The review was registered ( Number CRD42013004632 ) on PROSPERO , the International Prospect i ve Register of Systematic Review s. Results The results indicated that PA is associated with significant and beneficial changes in fat percentage , waist circumference , systolic blood pressure , insulin , low-density lipoprotein cholesterol , and total cholesterol , as well as with small non-significant changes in diastolic blood pressure , glucose , and high-density lipoprotein cholesterol .
Conclusion Although limited , results from controlled trials suggest that PA intervention may improve physical fitness and risk factors for cardiovascular disease in adolescents who are overweight or obese
Background The increasing prevalence of obesity in the pediatric age range has become a major concern .
Studies have investigated the role of physical activity ( PA ) to prevent obesity in this population .
However , previous review s did not focus on the effects of PA in overweight/obese adolescents on physical fitness and risk factors for cardiovascular disease altogether .
Objective The present systematic review analyzed trials investigating the effect of PA on aerobic capacity , muscle strength , body composition , hemodynamic variables , biochemical markers , and endothelial function in obese/overweight adolescents .