There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Impact of Diet on the Intestinal Microbiota in 10-month-old Infants
Objective : To investigate whether diet influences the composition of the intestinal microbiota in 10-month-old infants . Patients and Methods : Fecal sample s were collected from sixty-five 10-month-old infants participating in a r and omized 2 × 2 intervention study comparing cow 's milk ( CM ) with infant formula ( IF ) with or without fish oil ( FO ) supplement . Infants r and omized to CM received a daily iron supplement . Bacterial DNA was extracted from the feces . Polymerase chain reaction was performed with primers targeting the V3 and V6–8 region of the 16S rRNA gene and analyzed by denaturing gradient gel electrophoresis ( DGGE ) . Cluster analysis of the DGGE gels was performed by use of the Pearson correlation coefficient . Results : Sample s from infants receiving CM clustered differently than did those from the IF group in the V3-based DGGE gels ( P < 0.001 ) and showed a different distribution with or without FO in the CM group ( P = 0.001 ) but not in the IF group ( P = 0.39 ) . Repeat analysis with the V6–8-based DGGE gels showed the same pattern , although the V3 gels had 2.5 times as many b and s as the V6–8 gels . Conclusions : Consumption of CM or IF has a decisive influence on the composition of the intestinal microbiota .  Supplementation with FO showed an effect on the microbiota only in the CM group . We speculate that these differences could be influenced by the intake of iron and n-3 polyunsaturated fatty acids , respectively
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .