There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
[Effect of long-chain polyunsaturated fatty acids on arachidonate and docosahexaeonic acid in healthy infants in the first four months of life].
Fatty acid compositions of plasma phospholipids ( PL ) , triglycerides ( TG ) and sterol esters ( STE ) were measured by high resolution capillary gas-liquid chromatography in formula fed healthy infants at the ages of 5 days and 1 , 2 , 3 and 4 months . The infants were r and omly assigned to receive either conventional infant formula ( F , n = 10 ) without long-chain polyunsaturates ( LCP ) or the same formula supplemented with LCP ( LCP-F , n = 12 ) in amounts and ratios similar to those characteristic to human milk . From the age of 1 month onwards , percentage contributions of the principal omega-6 LCP , arachidonic acid were significantly higher in plasma lipids of infants fed LCP-F than in those receiving conventional formula without dietary LCP . Values of the principal omega-3 LCP , docosahexaenoic acid were also significantly lower in the infants fed conventional formula than in those receiving LCP-F throughout the study . The data obtained indicate that from the formula supplemented with LCP both arachidonic and docosahexaenoic acids were effectively absorbed and incorporated into infantile plasma lipids . Recent data of the literature suggest that supplementation of infant formula with LCP may beneficially influence visual and psychomotor development also in healthy , term infants
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .