Conclusions Short-term fish oil supplementation is associated with increasing the insulin sensitivity among those people with metabolic disorders
Background Fish oil supplementation has been shown to be associated with a lower risk of metabolic syndrome and benefit a wide range of chronic diseases , such as cardiovascular disease , type 2 diabetes and several types of cancers .
However , the evidence of fish oil supplementation on glucose metabolism and insulin sensitivity is still controversial .
This meta- analysis summarized the exist evidence of the relationship between fish oil supplementation and insulin sensitivity and aim ed to evaluate whether fish oil supplementation could improve insulin sensitivity .
Effects of supplementation with omega-3 on insulin sensitivity and non-esterified free fatty acid (NEFA) in type 2 diabetic patients.
OBJECTIVE The aim of this study was to determine the role of omega-3 supplementation on NEFA concentration , insulin sensitivity and resistance , and glucose and lipid metabolism in type 2 diabetic patients . SUBJECTS AND METHODS Forty-four type 2 diabetic patients were r and omly recruited into two groups . Group A received 4 g/day omega-3 soft gels , and group B received a placebo for 10 wks . Blood sample s were collected after 12-h fast . Physical activity records , three-day food records , and anthropometric measurements were obtained from all participants at the beginning and end of the study . RESULTS Omega-3 supplementation caused a significant reduction in NEFA in the intervention group compared with the placebo group ( P = 0.009 ) . Additionally , the administration of omega-3 result ed in significantly greater changes ( Diff ) for the intervention group in various parameters , such as insulin and Quicki indices compared with the placebo group ( P < 0.05 ) . CONCLUSIONS Omega-3 fatty acid supplementation in type 2 diabetic patients improved insulin sensitivity , probably due to the decrease in NEFA concentrations
Conclusions Short-term fish oil supplementation is associated with increasing the insulin sensitivity among those people with metabolic disorders
Background Fish oil supplementation has been shown to be associated with a lower risk of metabolic syndrome and benefit a wide range of chronic diseases , such as cardiovascular disease , type 2 diabetes and several types of cancers .
However , the evidence of fish oil supplementation on glucose metabolism and insulin sensitivity is still controversial .
This meta- analysis summarized the exist evidence of the relationship between fish oil supplementation and insulin sensitivity and aim ed to evaluate whether fish oil supplementation could improve insulin sensitivity .