In conclusion , we observed no improvement in muscle strength after the administration of vitamin D with or without calcium supplements .
We did find a small but significant deterioration of mobility .
BACKGROUND It has been suggested that vitamin D status or supplementation is important for maintaining or improving muscle strength and mobility in older adults .
The study results , however , do not provide consistent results .
We therefore aim ed to summarise the available evidence systematic ally , including only studies conducted in community-dwelling older persons .
The impact of sarcopenia on a physical activity intervention: The lifestyle interventions and independence for elders pilot study (LIFE-P)
Objective To determine if sarcopenia modulates the response to a physical activity intervention in functionally limited older adults . Design Secondary analysis of a r and omized controlled trial . Setting Three academic centers . Participants Elders aged 70 to 89 years at risk for mobility disability who underwent dualenergy x-ray absorptiometry ( DXA ) for body composition at enrollment and follow-up at twelve months ( N = 177 ) . InterventionS ubjects participated in a physical activity program ( PA ) featuring aerobic , strength , balance , and flexibility training , or a successful aging ( SA ) educational program about healthy aging . Measurements Sarcopenia as determined by measuring appendicular lean mass and adjusting for height and total body fat mass ( residuals method ) , Short Physical Performance Battery score ( SPPB ) , and gait speed determined on 400 meter course . Results At twelve months , sarcopenic and non-sarcopenic subjects in PA tended to have higher mean SPPB scores ( 8.7±0.5 and 8.7±0.2 points ) compared to sarcopenic and non-sarcopenic subjects in SA ( 8.3±0.5 and 8.4±0.2 points , p = 0.24 and 0.10 ) , although the differences were not statistically significant . At twelve months , faster mean gait speeds were observed in PA : 0.93±0.4 and 0.95±0.03 meters/second in sarcopenic and non-sarcopenic PA subjects , and 0.89±0.4 and 0.91±0.03 meters/second in sarcopenic and non-sarcopenic SA subjects ( p = 0.98 and 0.26 ) , although not statistically significant . There was no difference between the sarcopenic and non-sarcopenic groups in intervention adherence or number of adverse events . Conclusion These data suggest that older adults with sarcopenia , who represent a vulnerable segment of the elder population , are capable of improvements in physical performance after a physical activity intervention
In conclusion , we observed no improvement in muscle strength after the administration of vitamin D with or without calcium supplements .
We did find a small but significant deterioration of mobility .
BACKGROUND It has been suggested that vitamin D status or supplementation is important for maintaining or improving muscle strength and mobility in older adults .
The study results , however , do not provide consistent results .
We therefore aim ed to summarise the available evidence systematic ally , including only studies conducted in community-dwelling older persons .