The meta- analysis provides evidence that vegetarianism is associated with lower serum concentrations of hs-CRP when individuals follow a vegetarian diet for at least 2 years .
A vegetarian diet might be a useful approach to manage inflammaging in the long term
OBJECTIVE Vegetarian diets contain various anti-inflammatory components .
We aim ed to investigate the effects of  vegetarianism  on inflammatory biomarkers when compared with  omnivores .
Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet
Summary Background Evidence indicates that food-derived Maillard 's reaction products are absorbed and yet can be detected in the circulation . Aim of the study We postulated that consumption of the heat-treated food by omnivores could be reflected by higher plasma levels of advanced glycation end products ( AGEs ) in comparison with vegetarians , who in cooking ( by keeping away from meat ) use lower temperatures and less time for heating . Methods Plasma fluorescent AGEs ( 350/450 nm ) and Ne-(carboxymethyl)lysine ( CML , competitive ELISA ) levels were investigated in  3 groups of healthy vegetarians ( 9 vegans-V , 19 lacto-ovo-vegetarians – VLO and 14 semi-vegetarians – VS ) and compared with those of age-matched omnivores ( O , n=19 ) . Mean duration of vegetarian diet was V : 7.2±1.0 , VLO : 8.2±0.8 and VS : 7.9±1.1 years . Results Both fluorescent AGE ( O : 9.9±0.5 ; V : 10.8±0.7 , LO : 13.1±0.8 * and SV : 11.6±1.2 ×103 AU ) , and CML levels ( O : 427.1±15.0 , V : 514.8±24.6 * , LO : 525.7±29.5 * * , SV : 492.6±18.0 * ng/ml ) were significantly lower in omnivores than in vegetarians . Plasma glucose , parameters of renal function ( plasma concentration of creatinine and cystatin C , calculated glomerular filtration rate – GFR ) as well as C-reactive protein levels were within the normal range and did not differ significantly between the groups . Thus , neither decline of kidney function nor inflammatory processes contributed to the rise in plasma AGEs . Conclusion Enhanced plasma AGE levels in vegetarians in comparison to omnivores are herein presented for the first time . Mechanisms of AGE elevation and potential pathophysiological relevance of this finding are to be eluci date d in prospect i ve studies
The meta- analysis provides evidence that vegetarianism is associated with lower serum concentrations of hs-CRP when individuals follow a vegetarian diet for at least 2 years .
A vegetarian diet might be a useful approach to manage inflammaging in the long term
OBJECTIVE Vegetarian diets contain various anti-inflammatory components .
We aim ed to investigate the effects of  vegetarianism  on inflammatory biomarkers when compared with  omnivores .