Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .
[Do depressed patients comply with treatments prescribed?: a cross-sectional study of adherence to the antidepressant treatment].
INTRODUCTION . Compliance with antidepressant treatment is a very relevant factor in the outcome of depressive disorders . Poor compliance has been associated with worse outcome , increased rate of relapses and greater cost . This study has aim ed to describe adherence to antidepressant treatment in a sample of primary care patients with a diagnosis of depression in 2007 . METHODS . R and omized sampling was made of patients with depression and antidepressant treatment attended in two primary care teams . Their medical records were review ed to obtain the total number of prescriptions given to patients and the total number of prescriptions dispensed in the pharmacies . The difference between prescriptions written and collected was calculated . A difference of ± 2 was considered as good compliance . Results are shown as percentages . Comparisons were made with the chi-square , Student ’s T and ANOVA tests , where appropriate . RESULTS . The simple was made up of 212 patients . Mean age was 63.2 years ( SD 15.27 ) . In the sample , 66.5 % were treated with only one antidepressant and 24.1 % with two . The percentage of non-compliance was 33.96 % ( 95 % CI : 25.35–40.57 ) . Treatment-adherent patients have a lower percentage of long-term treatment with other drugs . The percentage of treatment-adherent women was higher than non-adherent ( p=0.015 ) . No differences were found in compliance among patients treated in the mental health center . CONCLUSIONS . One third of patients on antidepressant drug treatment were non-compliers because the drugs were not picked up properly from the pharmacies . We need to develop strategies to improve the therapeutic adherence of patients
Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .