The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .
Diabetes mellitus and serum carotenoids: findings of a population-based study in Queensland, Australia.
BACKGROUND Epidemiologic evidence suggests that serum carotenoids are potent antioxidants and may play a protective role in the development of chronic diseases including cancers , cardiovascular disease , and inflammatory diseases . The role of these antioxidants in the pathogenesis of diabetes mellitus remains unclear . OBJECTIVE This study examined data from a cross-sectional survey to investigate the association between serum  carotenoids  and  type 2 diabetes .  DESIGN Study participants were adults aged > or = 25 y ( n = 1597 ) from 6 r and omly selected cities and towns in Queensl and , Australia . Study examinations conducted between October and December 2000 included fasting plasma glucose , an oral-glucose-tolerance test , and measurement of the serum concentrations of 5 carotenoid compounds .  RESULTS Mean 2-h postload plasma glucose and fasting insulin concentrations decreased significantly with increasing quintiles of the 5 serum carotenoids -- alpha-carotene , beta-carotene , beta-cryptoxanthin , lutein/zeaxanthin , and lycopene . Geometric mean concentrations for all serum carotenoids decreased ( all decreases were significant except that of lycopene ) with declining glucose tolerance status . Beta-carotene had the greatest decrease , to geometric means of 0.59 , 0.50 , and 0.42 micromol/L in persons with normal glucose tolerance , impaired glucose metabolism , and type 2 diabetes , respectively ( P < 0.01 for linear trend ) , after control for potential confounders . CONCLUSIONS Serum carotenoids are inversely associated with type 2 diabetes and impaired glucose metabolism . R and omized trials of diets high in carotenoid-rich vegetables and fruit are needed to confirm these results and those from other observational studies . Such evidence would have very important implication s for the prevention of diabetes
The literature on risk factors for cardiometabolic diseases showed that lutein might be beneficial for atherosclerosis and inflammatory markers , but there were inconsistent associations with blood pressure , adiposity , insulin resistance , and blood lipids .
CONCLUSIONS Our findings suggest that higher dietary intake and higher blood concentrations of lutein are generally associated with better cardiometabolic health .
BACKGROUND The antioxidant lutein is suggested as being beneficial to cardiometabolic health because of its protective effect against oxidative stress , but evidence has not systematic ally been evaluated .
OBJECTIVE We aim ed to evaluate systematic ally the effects of lutein ( intake or concentrations ) on cardiometabolic outcomes in different life stages .