The current evidence suggests no difference between the types of material s after 12 months but favours composite resin adhesives after a > 14-month period .
The clinical relevance of this study is that RM-GIC may have the same clinical debonding ( failure ) rate as composite resin adhesives after 1 year when used for bonding of orthodontic brackets
The aim of this systematic review was to establish whether the clinical debonding ( failure ) rates of orthodontic brackets bonded either with resin-modified glass ionomer ( RM-GIC ) or with composite resin adhesive  are the same .
Evidence favoring the use of anticoagulants in the hospital phase of acute myocardial infarction.
Since the last comprehensive review of anticoagulation in acute myocardial infa rct ion four additional r and omized control trials have been reported . The overwhelming majority of all trials favored anticoagulation .  Rates of thromboembolism were higher in the control , and hemorrhagic complications in the anticoagulated group . Pooling of all r and omized control trials gives mean case fatality rates of 19.6 % for the control and 15.4 % for the anticoagulated group , a relative reduction of 21 % ( P less than 0.05 or less than 0.001 , depending on the analytic method ) . Five of six r and omized control trials reported " no effect " because the difference favoring anticoagulation was not statistically significant . However , sample sizes in these " negative " papers were too small to protect against missing a 21 % reduction in true case fatality rate due to anticoagulation ( beta greater than 0.10 ) . All patients who present no specific contraindication should receive  anticoagulants  during hospitalization for infa rct ion
The current evidence suggests no difference between the types of material s after 12 months but favours composite resin adhesives after a > 14-month period .
The clinical relevance of this study is that RM-GIC may have the same clinical debonding ( failure ) rate as composite resin adhesives after 1 year when used for bonding of orthodontic brackets
The aim of this systematic review was to establish whether the clinical debonding ( failure ) rates of orthodontic brackets bonded either with resin-modified glass ionomer ( RM-GIC ) or with composite resin adhesive  are the same .