Bariatric surgery  significantly lowered inflammatory factors ; however , baseline BMI , follow-up duration and type of surgery could impact the extent of observed effects
Obesity is one of the main causes of inflammation .
Previous studies have reported inconclusive results regarding the effect of bariatric surgery on inflammatory markers .
This systematic review and meta- analysis is aim ed at describing the effect of bariatric surgery on C-reactive protein ( CRP ) , interleukin-6 ( IL-6 ) , tumor necrosis factor-α ( TNF-α ) .
Impact of Laparoscopic Sleeve Gastrectomy on Iron Indices: 1 Year Follow-Up
Background Laparoscopic sleeve gastrectomy ( LSG ) has been recently introduced as a st and -alone , restrictive bariatric surgery . Theoretically , LSG attenuates micronutrients deficiencies and associated complications that typically observed following malabsorptive procedures . The aim of this study was to assess iron indices and the 1-year incidence of iron deficiency in patients undergoing LSG .  Methods This was a prospect i ve , cohort study ; patients who underwent LSG from June 2007 to April 2008 at our institution were screened for inclusion . Preoperative hemoglobin and iron indices including serum iron , transferrin saturation , ferritin , and soluble transferrin receptor were compared to their levels at 6 and 12 months after surgery . Similarly , vitamin B12 and red blood cell ( RBC ) folate were analyzed as secondary end points . Weight parameters and C-reactive protein ( CRP ) levels were compared before surgery and 1 year postoperatively . Results A total of 61 patients were included in the study . One year after surgery , there was a significant decrease in the mean body mass index from 47.5 ± 9.6 to 30.5 ± 6.5 ( P < 0.001 ) . The incidence of iron deficiency was 4.9 % at both follow-up time points . Anemia was evident in 4.9 % of patients 1 year postoperatively . Significant decrease in the means of the natural logarithm of vitamin B12 and RBC folate were observed as early as 6 months after surgery ( P = 0.014 ; P < 0.005 , respectively ) . The decrease in mean CRP level 12 months postoperatively was statistically significant compared to its preoperative value ( P < 0.0001 ) . Conclusion LSG is an effective procedure for the treatment of morbid obesity and its associated inflammatory state . One year after surgery , development of iron deficiency was insignificant
Bariatric surgery  significantly lowered inflammatory factors ; however , baseline BMI , follow-up duration and type of surgery could impact the extent of observed effects
Obesity is one of the main causes of inflammation .
Previous studies have reported inconclusive results regarding the effect of bariatric surgery on inflammatory markers .
This systematic review and meta- analysis is aim ed at describing the effect of bariatric surgery on C-reactive protein ( CRP ) , interleukin-6 ( IL-6 ) , tumor necrosis factor-α ( TNF-α ) .