There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Alpha linolenic acid in cholesterol esters: a marker of alphalinolenic acid intake in newborns
Objective : To evaluate α-linolenic acid ( ALA ) ( 18∶3 n-3 ) and linolenic acid ( LA ) ( 18∶2 n-6 ) in cholesterol esters ( CE ) as markers of ALA and LA dietary intakes in preterm infants . Subjects : Forty-five preterm infants : two groups fed different formulas , the third fed human milk .  Design : ALA and LA dietary intakes were precisely recorded in each infant to accurately determine the cumulative amount of ingested ALA and LA during two intervals : ( i ) between the second day after the first significant formula intake ( D0 ) and the fifteenth day ( D15 ) ; and ( ii ) between D0 and the first day of the 37th week of post-conception age ( W37 ) . The corresponding amounts of ingested ALA and LA were related to ALA and LA levels determined by capillary column gas – liquid chromatography in plasma cholesterol esters at D15 and W37 , respectively . Results : ALA in CE was very significantly correlated to D0–D15 and D0–W37 ALA intakes ( 0.66 ; P=0.0001 and 0.70 ; P=0.0001 ) , respectively . LA in CE was weakly correlated to D0–D15  LA intakes ( 0.03 ; P=0.01 ) and whatever the group ( human milk or enriched formula ) the correlation was lost at W37 . Conclusion : In preterm infants  , ALA in CE can be considered as representative of ALA dietary intakes , whereas LA in CE appears as a poor marker of LA intakes . European Journal of Clinical Nutrition ( 2000 ) 54 ,
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .