Grade B evidence also suggested that exercise may improve prostate cancer patients ' muscle mass , muscular strength , functional performance ( walking and sit to st and speed ) , as well as health-related , social and physical quality of life .
These effects appeared greater for group-rather than home-based-exercise , especially if these programs included resistance training .
CONTEXT Prostate cancer patients , especially those on and rogen deprivation therapy ( ADT ) , experience many symptoms that make it difficult to maintain their independence and quality of life .
Because ADT acts by means of reducing testosterone production , exercise may offset many of the ADT side effects and those of the cancer itself .
OBJECTIVES This systematic review of the literature evaluates whether exercise could reduce symptoms and improve quality of life for prostate cancer patients .
Prospective evaluation of the prevalence and severity of fatigue in patients with prostate cancer undergoing radical external beam radiotherapy and neoadjuvant hormone therapy.
OBJECTIVE To prospect ively evaluate the prevalence and severity of fatigue and its impact on quality of life ( QOL ) during and after radical external beam radiotherapy ( RT ) for prostate cancer . METHOD AND MATERIAL S Twenty-eight men with prostate cancer undergoing RT over 6 - 8 consecutive weeks were prospect ively accrued . The  Brief Fatigue Inventory ( BFI ) , a vali date d fatigue assessment tool , was administered at five time points : baseline ( week 1 ) , middle of RT ( week 3 - 4 ) , end of RT ( last week of RT ) , and follow-up ( median 6.5 weeks after RT ) . The BFI contained nine questions , each using 0 - 10 ratings to quantify fatigue severity and interference with six QOL domains . The prevalence of moderate-severe fatigue was plotted as a function of time . Mean sum and subscale scores at each time point were compared to baseline scores using Wilcoxon tests . Linear regression analyses were performed to assess associations between fatigue scores and age , tumor and treatment characteristics . RESULTS The median age was 69 years ( range 57 - 84 ) , Gleason score 7 ( range 6 - 10 ) , and presenting PSA 9.0 ng/mL ( range 2.5 ng/mL-103.0 ng/mL ) . Patients were treated once daily to a median dose of 74 Gy ( range 60 Gy-78 Gy ) over a median of 37 fractions ( range 30 - 39 ) . Hormone therapy was used in all patients ( median duration 12.2 months ) . The prevalence of moderate-severe present fatigue increased from 7 % at baseline to 8 % at mid-RT and 32 % at RT completion . Compared to baseline ( mean score 11.5 ) , fatigue increased significantly mid-RT ( mean score 14.6 , p = 0.03 ) and peaked at the end of RT ( mean score 23.5 , p = 0.001 ) . Fatigue significantly interfered with walking ability , normal work , daily chores , and enjoyment of life only at the end of RT . After RT completion , fatigue improved but remained higher compared to baseline at 6.5 weeks of follow-up ( mean score 15.0 , p = 0.02 ) . On linear regression analysis , age , Gleason score , PSA , T-stage , hormone therapy duration , RT dose and fractions were not significantly associated with mean fatigue scores . CONCLUSION Patients undergoing 6 - 8 weeks of RT experienced significant fatigue adversely affecting QOL persisting after therapy completion . Since walking ability was not affected until the end of RT , a walking exercise intervention to combat fatigue is likely feasible and is being investigated
Grade B evidence also suggested that exercise may improve prostate cancer patients ' muscle mass , muscular strength , functional performance ( walking and sit to st and speed ) , as well as health-related , social and physical quality of life .
These effects appeared greater for group-rather than home-based-exercise , especially if these programs included resistance training .
CONTEXT Prostate cancer patients , especially those on and rogen deprivation therapy ( ADT ) , experience many symptoms that make it difficult to maintain their independence and quality of life .
Because ADT acts by means of reducing testosterone production , exercise may offset many of the ADT side effects and those of the cancer itself .
OBJECTIVES This systematic review of the literature evaluates whether exercise could reduce symptoms and improve quality of life for prostate cancer patients .