Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .
Caffeines enhancement of maximal voluntary strength and activation in uninjured but not injured muscle.
The study 's objective was to determine whether orally ingested caffeine could help overcome excitation-contraction-coupling failure , which has been suggested to explain part of the strength loss associated with eccentric-contraction-induced muscle injury . A sample of 13 college students ( 4 men and 9 women ) was used in a double-blind , repeated- measures experimental design . Each participant performed 2 experimental trials , 1 with each leg , with each trial lasting 4 consecutive days . On a given day , each participant was r and omly assigned to ingest a capsule containing 6 mg/kg of either caffeine or flour ( placebo ) . On the day of and the first 2 days after a bout of 50 injurious eccentric contractions done by the knee extensors , the interpolated-twitch technique was used to assess electrically evoked strength , maximal voluntary isometric contraction ( MVIC ) strength , and percent muscle activation during MVIC both before and after capsule ingestion . These variables were also measured before and after capsule ingestion the day before the eccentric-contraction bout -- when the muscle was uninjured . In injured muscle , caffeine had no effect on any variable . In uninjured muscle , caffeine also had no effect on electrically evoked strength but increased MVIC strength by 10.4 % compared with placebo ( p = .00002 ) , and this was attributed to an increase in muscle activation ( 6.2 % ; p = .01 ) . In conclusion , the data provide no evidence that caffeine ingestion can help overcome excitation-contraction-coupling failure , if it exists , in injured human muscle . The data do indicate that caffeine ingestion can increase MVIC strength and activation in uninjured muscle but not in injured muscle
Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .