CONCLUSIONS Antihypertensive treatment reduces the risk of mortality and cardiovascular morbidity in people with diabetes mellitus and a systolic blood pressure more than 140 mm Hg .
If systolic blood pressure is less than 140 mm Hg , however , further treatment is associated with an increased risk of cardiovascular death , with no observed benefit
OBJECTIVE To assess the effect of antihypertensive treatment on mortality and cardiovascular morbidity in people with diabetes mellitus , at different blood pressure levels .
Effects of intensive blood pressure control in the management of patients with type 2 diabetes mellitus in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.
To appreciate the importance of the Action to Control Cardiovascular Risk in Diabetes ( ACCORD ) trial,1 one needs to remember that the systolic blood pressure ( BP ) target currently recommended by major guidelines for diabetic patients , that is , 130 mm Hg , except in the Appropriate Blood Pressure Control in Diabetes Study ( ABCD ) normotensive trial,7 which consisted of only a few hundred patients and had changes in creatinine clearance as the primary end point . Thus , ACCORD represents the only large-scale r and omized trial that provides information on what happens to the cardiovascular risk of diabetic patients  when SBP is reduced to 130 mm Hg as a result of r and omization to the usual ( rather than the tight ) BP control treatment strategy . Thus , the message from ACCORD to guidelines and clinical practice is that in diabetic patients it is not necessary to adopt
CONCLUSIONS Antihypertensive treatment reduces the risk of mortality and cardiovascular morbidity in people with diabetes mellitus and a systolic blood pressure more than 140 mm Hg .
If systolic blood pressure is less than 140 mm Hg , however , further treatment is associated with an increased risk of cardiovascular death , with no observed benefit
OBJECTIVE To assess the effect of antihypertensive treatment on mortality and cardiovascular morbidity in people with diabetes mellitus , at different blood pressure levels .