Aerobic exercise did not improve BASFI , CRP or ESR .
CONCLUSION Aerobic exercise did not provide beneficial effects either on disease activity or on physical function and biological parameters when compared to a control group in axial spondyloarthritis
AIM To evaluate the impact of an aerobic fitness program on disease activity , defined by the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI ) and on C-reactive protein ( CRP ) , erythrocyte sedimentation rate ( ESR ) and the Bath Ankylosing Spondylitis Functional Index ( BASFI ) in case of axial spondyloarthritis .
Effect of a high-intensity weight-bearing exercise program on radiologic damage progression of the large joints in subgroups of patients with rheumatoid arthritis.
OBJECTIVE To investigate whether a high-intensity exercise program accelerates the rate of radiologic damage of the large joints in predefined subgroups of patients with rheumatoid arthritis . METHODS The data of 277 participants in a 2-year r and omized controlled trial , comparing the effects of high-intensity exercises with usual care  , were used . Linear regression analysis was used to test which predefined variables at baseline ( age , disease duration , disease activity , physical capacity , functional ability , joint damage ) modified the effect of high-intensity exercise on the progression of radiologic damage of the large joints over 24 months . RESULTS Baseline radiologic joint damage was the only variable associated with the effect of high-intensity exercise on joint damage progression in large joints . In a subgroup of 218 patients with no or little joint damage ( defined as Larsen score < or = 5 ; 80 % of our study population ) the proportions of patients with an increase in joint damage were similar for the exercise and usual-care group ( 35 % versus 36 % , risk ratio [ RR ] 1.0 [ 0.7 - 1.4 ] ; P = not significant ) , whereas , in a subgroup of 59 patients who already had extensive damage of large joints ( defined as Larsen score > 5 ) the proportion was significantly higher in the exercise group ( 85 % versus 48 % , RR 1.8 [ 1.2 - 2.6 ] ; P < 0.05 ) . CONCLUSION High-intensity weight-bearing exercises appear to accelerate joint damage progression in patients with preexisting extensive damage . Patients with extensive large joint damage should , therefore , be advised to refrain from activities excessively loading the damaged joints
Aerobic exercise did not improve BASFI , CRP or ESR .
CONCLUSION Aerobic exercise did not provide beneficial effects either on disease activity or on physical function and biological parameters when compared to a control group in axial spondyloarthritis
AIM To evaluate the impact of an aerobic fitness program on disease activity , defined by the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI ) and on C-reactive protein ( CRP ) , erythrocyte sedimentation rate ( ESR ) and the Bath Ankylosing Spondylitis Functional Index ( BASFI ) in case of axial spondyloarthritis .