In regards to surgery it is recommended to perform total omentectomy since subclinic metastasis have been documented in 10 - 30 % of all cases , and systematic limphadenectomy , necessary to be able to obtain an adequate surgical staging .
Minimal invasion surgery is not a recommended procedure for the treatment of advanced ovarian cancer .
Radiotherapy can be used to palliate symptoms .
In the present , there is not a st and ardized screening method .
Diagnosis in early stages means a better survival .
Radiotherapy can be indicated to palliate symptoms
INTRODUCTION Ovarian cancer ( OC ) is the third most common gynecologic malignancy worldwide .
Most of cases it is of epithelial origin .
At the present time there is not a st and ardized screening method , which makes difficult the early diagnosis .
The 5-year survival is 90 % for early stages , however most cases present at advanced stages , which have a 5-year survival of only 5 - 20 % .
GICOM collaborative group , under the auspice of different institutions , have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia .
Until now , laparoscopy for diagnostic-staging surgery is not well known as a recommended method .
In advanced stages , primary cytoreduction is recommended as initial treatment .
Implications of second-look laparotomy in the context of optimally resected stage III ovarian cancer: a non-randomized comparison using an explanatory analysis: a Gynecologic Oncology Group study.
OBJECTIVE A non-r and omized comparison of outcome in women undergoing second-look laparotomy ( SLL ) or clinical follow-up , after receiving six cycles of combination chemotherapy with paclitaxel plus either cisplatin or carboplatin , for optimally resected stage III ovarian cancer . METHODS Prior to chemotherapy r and omization , patients chose whether or not to undergo SLL ; this was a stratification factor to insure balance of treatment assignment . Any subsequent therapy was physician-directed . Explanatory analysis replaced intent-to-treat because of a higher likelihood of detecting SLL effect in the presence of noncompliance . RESULTS There were 393 patients ( median age : 54 ) who Elected SLL and 399 ( median age : 59 ) who Elected No SLL . The former group was more likely to have gross residual disease at initial surgery than the latter group ( 69 % versus 60 % , respectively ) . In the Elected SLL group , 59 ( 15 % ) patients subsequently refused surgery , in nine ( 2 % ) surgery was contraindicated , and 31 ( 8 % ) relapsed or died prior to the procedure . Cancer was found in 46 % of 294 ( 75 % ) patients undergoing SLL . Since early failures ( prior to SLL ) do not address benefit , such patients ( SLL : 32 ; No SLL : 33 ) , defined as progression-free survival ( PFS ) < 6 months , were excluded from analysis . The adjusted relative risk of progression is 0.89 ( 95 % confidence interval : 0.75 , 1.07 ) ; the difference in median PFS is 1.0 month ( SLL : 23.9 months ; No SLL : 22.9 months ) . The survival rate curves are superimposable . CONCLUSION In the context of a non-r and omized comparison , the performance of a SLL was not associated with longer survival
In regards to surgery it is recommended to perform total omentectomy since subclinic metastasis have been documented in 10 - 30 % of all cases , and systematic limphadenectomy , necessary to be able to obtain an adequate surgical staging .
Minimal invasion surgery is not a recommended procedure for the treatment of advanced ovarian cancer .
Radiotherapy can be used to palliate symptoms .
In the present , there is not a st and ardized screening method .
Diagnosis in early stages means a better survival .
Radiotherapy can be indicated to palliate symptoms
INTRODUCTION Ovarian cancer ( OC ) is the third most common gynecologic malignancy worldwide .
Most of cases it is of epithelial origin .
At the present time there is not a st and ardized screening method , which makes difficult the early diagnosis .
The 5-year survival is 90 % for early stages , however most cases present at advanced stages , which have a 5-year survival of only 5 - 20 % .
GICOM collaborative group , under the auspice of different institutions , have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia .
Until now , laparoscopy for diagnostic-staging surgery is not well known as a recommended method .
In advanced stages , primary cytoreduction is recommended as initial treatment .