The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile .
The mechanisms of action are still being studied .
ABSTRACT In this systematic review , we discuss the scientific evidence about the effect of dietary intake of seeds and sesame derivatives on lipid profile and blood pressure ( BP ) of hypertensive and dyslipidemic individuals .
Sesame oil consumption exerts a beneficial effect on endothelial function in hypertensive men
Background : The aim of the study was to investigate the effects of sesame oil on endothelial function and to detect the underlying mechanisms , both in the postpr and ial state and after long-term consumption . Design : We enrolled 30 hypertensive men in a two-phase study . In the first phase , 26 volunteers consumed 35 g of either sesame oil or control oil .  Endothelial function , inflammatory activation and nitric oxide syntase ( NOS ) inhibition was assessed after a 12-hour fast and 2 hours after consumption of an oil-containing st and ardized meal . In the second phase , 30 volunteers consumed 35 g of sesame oil or control oil daily for 2 months and the above-mentioned parameters were assessed at baseline , 15 , 30 and 60 days . Methods : Endothelial function was estimated by endothelium-dependent FMD ( flow-mediated dilatation ) of the brachial artery . Results : Flow-mediated dilatation ( FMD ) improved significantly both after acute ( p = 0.001 ) and long-term sesame oil consumption ( p = 0.015 , p = 0.005 and p = 0.011 for 15 , 30 and 60 days respectively ) . Intracellular adhesion molecule ( ICAM ) levels decreased significantly after only 60 days of daily sesame oil intake ( p = 0.014 ) . By contrast , no changes were observed in the control group in either phase of the study . Conclusions : This is the first study to show that sesame oil consumption exerts a beneficial effect on endothelial function and this effect is sustained with long-term daily use
The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile .
The mechanisms of action are still being studied .
ABSTRACT In this systematic review , we discuss the scientific evidence about the effect of dietary intake of seeds and sesame derivatives on lipid profile and blood pressure ( BP ) of hypertensive and dyslipidemic individuals .