These results provide evidence that olive oil might exert beneficial effects on endothelial function as well as markers of inflammation and endothelial function , thus representing a key ingredient contributing to the cardiovascular-protective effects of a Mediterranean diet .
The aim of the present systematic review was to synthesize data from r and omized controlled trials investigating the effects of olive oil on markers of inflammation or endothelial function .
Low-dose fish oil supplementation increases serum adiponectin without affecting inflammatory markers in overweight subjects.
Obesity is associated with an increased risk of cardiovascular disease , whereas long-chain n-3 polyunsaturated fatty acids ( PUFAs ) from fish may have cardioprotective and anti-inflammatory effects . This study aim ed to investigate the hypothesis that acute and short-term supplementation with a low dose of marine n-3 PUFA exerts an anti-inflammatory effect in overweight subjects . In a double-blind , placebo-controlled trial with 2 parallel groups , 50 overweight subjects were r and omized to receive daily supplementation with 2 capsules containing either 2 g of fish oil ( 1.1 g marine n-3 PUFA ) or 2 g of olive oil .  Blood sample s and adipose tissue biopsies were collected at baseline , after 1 day ( acute effect ) , and after 6 weeks ( short-term effect ) of supplementation . No significant effects were seen after supplementation for 1 day , but after 6 weeks , subjects receiving fish oil had a significant increase in the n-3 PUFA content of granulocytes and adipose tissue ( P < .01 ) . Serum adiponectin levels were increased by 0.55 μg/mL ( 95 % confidence interval , 0.02 - 1.08 ) in the fish oil group compared with the control group ( P = .04 ) after 6 weeks of supplementation . Levels of interleukin 6 were inversely correlated to the marine n-3 PUFA content of granulocytes and adipose tissue at baseline ( excluding α-linolenic acid ) . In conclusion , daily supplementation with 1.1 g of marine n-3 PUFA  significantly increased serum adiponectin , but the effect was small , and no overall anti-inflammatory effect of the supplement could be demonstrated
These results provide evidence that olive oil might exert beneficial effects on endothelial function as well as markers of inflammation and endothelial function , thus representing a key ingredient contributing to the cardiovascular-protective effects of a Mediterranean diet .
The aim of the present systematic review was to synthesize data from r and omized controlled trials investigating the effects of olive oil on markers of inflammation or endothelial function .