In the meta-regression analysis , changes in plasma cortisol concentrations following statin therapy were found to be independent of treatment duration .
Results of this meta- analysis of RCTs suggest a significant elevation in plasma cortisol levels following statin therapy
This study aim ed to perform a systematic review and meta- analysis of r and omized controlled trials ( RCTs ) in order to calculate the effect size of statin therapy in changing plasma cortisol concentrations .
Mood changes in response to psychosocial stress in healthy young women: effects of pretreatment with cortisol.
Effects of cortisol on human mood during stress situations are still incompletely understood , although this topic has important clinical implication s. In this experiment , the mood of 44 healthy young women ( all oral contraceptive users ) was examined . A double-blind , r and omized , placebo-controlled time series paradigm was used . Subjects were treated with either 30-mg cortisol or placebo orally . Forty-five minutes later , subjects attended a psychosocial stress procedure ( Trier Social Stress Test ; TSST ; C. Kirschbaum , K. M. Pirke , & D. H. Hellhammer , 1993 ) . The course of the subjects ' mood as well as salivary cortisol and alpha-amylase levels were measured before and after the TSST . With regard to mood , it was found that the groups did not differ in mood before the TSST . After stress exposure , the subjective ratings of current mood state of cortisol-treated women were significantly less negative than that of placebo-treated subjects . These findings show that raising cortisol levels prior to acute stress has a protective effect on mood during stress situations . Results are discussed with regard to the context of specific adaptive effects of cortisol and the role of cortisol in posttraumatic stress disorder
In the meta-regression analysis , changes in plasma cortisol concentrations following statin therapy were found to be independent of treatment duration .
Results of this meta- analysis of RCTs suggest a significant elevation in plasma cortisol levels following statin therapy
This study aim ed to perform a systematic review and meta- analysis of r and omized controlled trials ( RCTs ) in order to calculate the effect size of statin therapy in changing plasma cortisol concentrations .