Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .
Identification of primary care patients at risk of nonadherence to antidepressant treatment
Introduction Poor adherence to antidepressant treatment is common , and results in increased disability and costs . Several factors are thought to influence patients ’ ability and willingness to adhere . So far , however , consensus is lacking regarding patient characteristics that predict nonadherence . The purpose of this study was to identify predictors of nonadherence to antidepressant treatment that can be ascertained at treatment start . Method The present study used data from a r and omized controlled trial with the main objective of study ing the effect of two different compliance-enhancing programs on treatment adherence  and treatment response in 1031 primary care patients with major depression . In this study , logistic regression analyses were performed to examine patient- and illness-related characteristics potentially associated with nonadherence . Results Nonadherence to antidepressant treatment  was predicted by age under 35 or over 64 years , presence of personality disorder , sensation-seeking personality traits , substance abuse , and absence of concomitant medications . Conclusion Certain patient- and illness-related characteristics may imply an increased risk of nonadherence to antidepressant treatment . Giving special attention to subjects with such characteristics may improve adherence
Individual patient ’s behaviors , lack of social support , clinical or treatment and illness-related , and health system factors influenced psychotropic medication non-adherence .
Conclusion Psychotropic medication non-adherence was high .
It was influenced by various factors operating at different levels .
Background Major psychiatric disorders are growing public health concern that attributed 14 % of the global burden of diseases .
The management of major psychiatric disorders is challenging mainly due to medication non-adherence .
However , there is a paucity of summarized evidence on the prevalence of psychotropic medication non-adherence and associated factors .
Therefore , we aim ed to summarize existing primary studies ’ finding to determine the pooled prevalence and factors associated with psychotropic medication non-adherence .