Because of the heterogeneity and the limited number of studies , there is no sufficient evidence on the potential role of vasomotor symptoms in metabolic health .
However , both high- quality cohort studies , with large study population s and adjustment for multiple confounding variables showed positive associations between vasomotor symptoms and insulin resistance and type 2 diabetes mellitus .
These findings suggest that there is an association between vasomotor symptoms and metabolic health outcomes .
The objective of this study was to systematic ally review studies describing the association between vasomotor symptoms and metabolic syndrome , type 2 diabetes and insulin resistance in peri- and postmenopausal women .
Accuracy of Subjective Hot Flush Reports Compared With Continuous Sternal Skin Conductance Monitoring
OBJECTIVE : To compare 2 subjective and 1 objective method for assessing hot flush frequency : prospect i ve paper hot flush diaries , prospect i ve electronic event markers , and the Biolog ambulatory sternal skin conductance monitor . METHODS : Fifty-five breast cancer survivors provided two 24-hour periods of data , 1 week apart , at baseline before being r and omized for an intervention study . Women completed a prospect i ve paper hot flush diary and pressed an event marker to subjectively record each hot flush they experienced while wearing a sternal skin conductance monitor . RESULTS : Sensitivity was uniformly low ( < 50 % ) for both subjective methods at each week . The estimated probability that a woman would record a true monitor-verified hot flush subjectively by diary or event marker was between 36 % and 50 % of the time if she was awake and between 22 % and 42 % of the time if she was asleep . Underreporting of diary hot flushes consequently result ed in more than 50 % missing severity and bother ratings . Specificity was high ( 96–98 % ) for both the diary and event marker , for both weeks , and for both waking and sleeping times . The positive predictive value was low ( 34–52 % ) , and negative predictive value was high ( 94–97 % ) . This indicates that , rather than overreporting hot flushes when they did not exist , women tended to underreport hot flushes when they did exist . CONCLUSION : Use of prospect i ve paper hot flush diaries and electronic event markers may seriously underestimate hot flush frequency and result in missed intensity and bother ratings . LEVEL OF EVIDENCE :
Because of the heterogeneity and the limited number of studies , there is no sufficient evidence on the potential role of vasomotor symptoms in metabolic health .
However , both high- quality cohort studies , with large study population s and adjustment for multiple confounding variables showed positive associations between vasomotor symptoms and insulin resistance and type 2 diabetes mellitus .
These findings suggest that there is an association between vasomotor symptoms and metabolic health outcomes .
The objective of this study was to systematic ally review studies describing the association between vasomotor symptoms and metabolic syndrome , type 2 diabetes and insulin resistance in peri- and postmenopausal women .