Aerobic exercise did not improve BASFI , CRP or ESR .
CONCLUSION Aerobic exercise did not provide beneficial effects either on disease activity or on physical function and biological parameters when compared to a control group in axial spondyloarthritis
AIM To evaluate the impact of an aerobic fitness program on disease activity , defined by the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI ) and on C-reactive protein ( CRP ) , erythrocyte sedimentation rate ( ESR ) and the Bath Ankylosing Spondylitis Functional Index ( BASFI ) in case of axial spondyloarthritis .
ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitis
Objectives : To evaluate various validity aspects of four disease activity scores ( ASDAS ) for ankylosing spondylitis ( AS ) in comparison with the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI ) , its individual components and physician and patient global assessment of disease activity . Methods : The analyses were performed in two cohorts of patients with AS : ( 1 ) the NOR-DMARD data base which includes patients starting on a disease-modifying antirheumatic drug or tumour necrosis factor ( TNF ) blocker and ( 2 ) patients participating in double-blind placebo controlled r and omised clinical trials with TNF blockers in four centres . Discrimination between patients with low versus high disease activity according to various definitions and between various levels of change were analysed as the st and ardised mean difference ( difference in the group means divided by the pooled SD of the group means ) and t score . Results : The four ASDAS versions were highly discriminatory in differentiating patients with different levels of disease activity and patients with different levels of change . The ASDAS scores outperformed the BASDAI and its single components in all setting s : patient- or physician-based , reflecting status or change , with normal or raised C-reactive protein ( CRP ) , in the presence or absence of peripheral arthritis . There were no major differences between the four ASDAS scores . Based on feasibility , the ASAS membership selected the ASDAS version which included back pain , duration of morning stiffness , patient global assessment , peripheral joint complaints and CRP as the preferred version . Conclusions : The ASDAS is a vali date d , highly discriminatory instrument for assessing disease activity in AS , including patient-reported outcomes and CRP levels
Aerobic exercise did not improve BASFI , CRP or ESR .
CONCLUSION Aerobic exercise did not provide beneficial effects either on disease activity or on physical function and biological parameters when compared to a control group in axial spondyloarthritis
AIM To evaluate the impact of an aerobic fitness program on disease activity , defined by the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI ) and on C-reactive protein ( CRP ) , erythrocyte sedimentation rate ( ESR ) and the Bath Ankylosing Spondylitis Functional Index ( BASFI ) in case of axial spondyloarthritis .