The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .
Comparison between 3 triclosan dentifrices on plaque, gingivitis and salivary microflora.
3 triclosan-containing dentifrices were compared in a 6-month , unsupervised tooth brushing study . The effects on plaque , gingival bleeding and certain salivary micro-organisms ( mutans streptococci , lactobacilli , total counts of streptococci and total counts of micro-organisms ) were evaluated . 123 subjects were divided into 4 groups according to severity of gingival bleeding index . 112 subjects completed the study . Following a 4-week pre-experimental period , using a sodium monofluorophosphate dentifrice ( placebo ) , the subjects were assigned to use one of 3 triclosan-containing dentifrices , available on the Swedish market : Colgate Paradent ( a triclosan/copolymer dentifrice ) ( n = 26 ) ; Pepsodent Gum Health ( a triclosan/zinc citrate dentifrice ) ( n = 31 ) ; Dentosal Friskt T and kött ( a triclosan/pyrophosphate dentifrice ) ( n = 28 ) ; or to continue with the placebo ( n = 27 ) . The results revealed that Colgate Paradent reduced baseline plaque values by 39 % ( Quigley and Hein ) over the 6-month experimental period . The corresponding values for the other modalities were : a reduction of 6 % for Pepsodent Gum Health , an increase of 5 % for Dentosal Friskt T and kött , and an increase of 2 % for placebo . A significant difference in the plaque levels ( p < 0.05 ) was found between Colgate Paradent and Pepsodent Gum Health and between Colgate Paradent and placebo . The gingival bleeding index was improved in all 4 groups . A significant difference ( p < 0.05 ) was found with respect to bleeding between Colgate Paradent and placebo ( p < 0.05 ) at the 3-month registration . A statistically significant increase over time in total number of streptococci and total colony forming units were found for the Dentosal , Pepsodent and placebo groups , but not for Colgate . ( ABSTRACT TRUNCATED AT 250 WORDS
The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .