This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .
Whether vitamin D3 is effective in reducing proteinuria in type 2 diabetic patients?
Background : Nowadays Vitamin D deficiency is a notable medical condition world-wide and also in Iran . Since , vitamin D can have renoprotective effect by inhibiting the renin-angiotensin system ; it appears that low vitamin D level can worsen the renal injury in diabetic patients . This study demonstrates the effect of vitamin D3 therapy on reducing proteinuria in diabetic patients with concomitant diabetic nephropathy and vitamin D deficiency after controlling hypertension and use of angiotensin converting enzyme inhibitors ( ACEIs ) or angiotensin II type receptor blockers ( ARBs ) . Material s and Methods : In this r and omized double blinded parallel groups clinical trial , 51 diabetic patients with proven nephropathy and vitamin D deficiency/insufficiency and stable hypertension , dyslipidemia , and hyperglycemic treatment were enrolled . The patients were divided r and omly into two groups ( treatment and placebo group ) . Patients received oral vitamin D3 ( pearl 50000 IU ) or placebo one pearl every week for 12 weeks . Patients were assessed at baseline and 12 weeks after intervention from the point of 25(OH ) D level , and urine albumin/creatinine ration ( UACR ) . Results : Mean serum 25(OH ) D concentrations were 14.06 ng/ml and 16.05 ng/ml before treatment . Furthermore , after intervention , its levels were risen to 71.23 and 17.63 in drug and placebo groups , respectively . Whereas , UACR as the main variable did not change significantly after intervention in both groups ( P = 0.919 ) . Conclusion : According to our finding , there was not a decrease in proteinuria in diabetic patients who received vitamin D for a period of 3 months
This meta- analysis suggests that vitamin D supplementation improves indices of glycemic control ( FBG , HOMA-IR , and HbA1C ) in patients with diabetes mellitus .
Hence , vitamin D supplements may be of potential therapeutic value in diabetic patients , as an adjuvant therapy along with other treatments
BACKGROUND AND PURPOSE This systematic review and meta- analysis aim ed to assess the effects of vitamin D supplements on indices of glycemic control [ homeostatic model assessment -insulin resistance ( HOMA-IR ) , hemoglobin A1C ( HbA1C ) , fasting blood glucose ( FBG ) , and quantitative insulin-sensitivity check index ( QUICKI ) and lipid profile in diabetic patients .