Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .
Comparison of the effects of oat bran and low-fiber wheat on serum lipoprotein levels and blood pressure.
Previous studies have shown that supplementation of the diet with oat bran may lower serum cholesterol levels . However , it is not known whether oat-bran diets lower serum cholesterol levels by replacing fatty foods in the diet or by a direct effect of the dietary fiber contained in oat bran . To determine which is the case , we compared the effect of isocaloric supplements of high-fiber oat bran ( 87 g per day ) and a low-fiber refined-wheat product on the serum lipoprotein cholesterol levels of 20 healthy subjects , 23 to 49 years old . After a one-week base-line period during which they consumed their usual diets , the subjects were given each type of supplement for six-week periods in a double-blind , crossover trial . Mean serum cholesterol levels ( + /- SD ) were not significantly different during the high-fiber and low-fiber periods : total cholesterol , 4.44 + /- 0.73 and 4.46 + /- 0.64 mmol per liter ( 172 + /- 28 and 172 + /- 25 mg per deciliter ) ; low-density lipoprotein , 2.69 + /- 0.63 and 2.77 + /- 0.59 mmol per liter ( 104 + /- 24 and 107 + /- 23 mg per deciliter ) ; and high-density lipoprotein , 1.40 + /- 0.39 and 1.32 + /- 0.39 mmol per liter ( 54.2 + /- 15.0 and 50.9 + /- 15.2 mg per deciliter ) , respectively . However , both types of supplements lowered the mean base-line serum cholesterol level , 4.80 + /- 0.80 mmol per liter ( 186 + /- 31 mg per deciliter ) , by 7 to 8 percent ( 95 percent confidence interval for high fiber , 11 to 4 percent , and for low fiber , 11 to 3 percent ) . The subjects ate less saturated fat and cholesterol and more polyunsaturated fat during both periods of supplementation than at base line . Those changes in dietary fats were sufficient to explain all of the reduction in serum cholesterol levels caused by the high-fiber and low-fiber diets . The average blood pressure was 112/68 mm Hg at base line and did not change during either dietary period . We conclude that oat bran has little cholesterol-lowering effect and that high-fiber and low-fiber dietary grain supplements reduce serum cholesterol levels about equally , probably because they replace dietary fats
Pooled analyses showed that oat β-glucan has a lowering effect on LDL-cholesterol , non-HDL-cholesterol and apoB. Inclusion of oat-containing foods may be a strategy for achieving targets in CVD reduction
Oats are a rich source of β-glucan , a viscous , soluble fibre recognised for its cholesterol-lowering properties , and are associated with reduced risk of CVD .
Our objective was to conduct a systematic review and meta- analysis of r and omised-controlled trials ( RCT ) investigating the cholesterol-lowering potential of oat β-glucan on LDL-cholesterol , non-HDL-cholesterol and apoB for the risk reduction of CVD .