CONCLUSIONS Probiotic consumption may improve glycemic control modestly .
Modification of gut microbiota by probiotic supplementation may be a method for preventing and control hyperglycemia in clinical practice
BACKGROUND Previous clinical trials indicate that probiotic consumption may improve blood glucose control , however , results from r and omized trials on glycemic control have been inconsistent .
OBJECTIVE To investigate the effects of probiotics on glycemic control in a systematic review and meta- analysis of r and omized controlled trials .
Effect of daily consumption of probiotic yoghurt on insulin resistance in pregnant women: a randomized controlled trial
Background / objectives : Owing to excess body weight and increased secretion of inflammatory cytokines primarily during the third trimester , pregnancy is associated with elevated insulin resistance . To our knowledge , no report is available indicating the effects of probiotic yoghurt consumption on serum insulin levels in pregnant women . This study was design ed to determine the effects of daily consumption of probiotic yoghurt on insulin resistance and serum insulin levels of Iranian pregnant women . Subjects/ methods : In this r and omized controlled clinical trial , 70 primigravida pregnant women with singleton pregnancy at their third trimester were participated . We r and omly assigned participants to consume 200 g per day of conventional ( n=33 ) or the probiotic group ( n=37 ) for 9 weeks . The probiotic yoghurt was a commercially available product prepared with the starter cultures of Streptococcus thermophilus and Lactobacillus bulgaricus , enriched with probiotic culture of two strains of lactobacilli ( Lactobacillus acidophilus LA5 ) and bifidobacteria ( Bifidobacterium animalis BB12 ) with a total of min 1 × 107 colony-forming units . Fasting blood sample s were taken at baseline and after 9-week intervention to measure fasting plasma glucose and serum insulin levels . Homeostatic model assessment of insulin resistance ( HOMA-IR ) was used to calculate insulin resistance score . Results : Although consumption of probiotic yogurt for 9 weeks did not affect serum insulin levels and HOMA-IR score , significant differences were found comparing changes in these variables between probiotic and conventional yogurts ( changes from baseline in serum insulin levels : + 1.2±1.2 vs + 5.0±1.1 μIU/ml , respectively , P=0.02 ; and in HOMA-IR score : −0.2±0.3 vs 0.7±0.2 , respectively , P=0.01 ) . Conclusions : It is concluded that in contrast to conventional yogurt , daily consumption of probiotic yogurt for 9 weeks maintains serum insulin levels and might help pregnant women prevent developing insulin resistance
CONCLUSIONS Probiotic consumption may improve glycemic control modestly .
Modification of gut microbiota by probiotic supplementation may be a method for preventing and control hyperglycemia in clinical practice
BACKGROUND Previous clinical trials indicate that probiotic consumption may improve blood glucose control , however , results from r and omized trials on glycemic control have been inconsistent .
OBJECTIVE To investigate the effects of probiotics on glycemic control in a systematic review and meta- analysis of r and omized controlled trials .