There was no increased risk of infections with IV iron .
Gastrointestinal AEs were reduced with IV iron .
CONCLUSION Intravenous iron therapy is not associated with an increased risk of SAEs or infections .
Infusion reactions are more pronounced with IV iron
OBJECTIVE To amass all available evidence regarding the safety of intravenous ( IV ) iron preparations to provide a true balance of efficacy and safety .
Intravenous administration of iron sucrose for treating anemia in postpartum women.
BACKGROUND To compare the efficacy of oral and intravenous administration of iron supplements for treating postpartum anemia . METHODS One hundred and four anemic postpartum women were studied prospect ively . The criteria for the diagnosis of anemia were Hb<8 gr/dl and ferritine<10 microg/dl . They were r and omised into two groups . Group A consisted of 78 women who received i.v . a total amount of 300 mg iron sucrose in three days . Group B consisted of 26 women , who received orally 800 mg iron proteinsuccinylate daily for four weeks . RESULTS At the end of the study , in group A the increase of Hb mean level was 4.6 gr/dl and of ferritin mean level was 105 mg/L. In group B the increase in hemoglobin mean level was 2.3 gr/dl and ferritin mean level was 68 mg/L. There was significant difference in the increase of hemoglobin level ( p=0.0001 ) and also in the increase in ferritin level ( p=0.0004 ) between the two groups . CONCLUSION Intravenous administration of iron sucrose seems to be safe and it helps postpartum women to recover early from anemia
There was no increased risk of infections with IV iron .
Gastrointestinal AEs were reduced with IV iron .
CONCLUSION Intravenous iron therapy is not associated with an increased risk of SAEs or infections .
Infusion reactions are more pronounced with IV iron
OBJECTIVE To amass all available evidence regarding the safety of intravenous ( IV ) iron preparations to provide a true balance of efficacy and safety .