Vitamin D supplementation had no statistically significant effects on total body bone mineral content ( BMC ) , hip bone mineral density ( BMD ) or forearm BMD .
These results do not support vitamin D supplementation to improve bone density in healthy children with normal vitamin D levels , but suggest that supplementation of deficient children may be clinical ly useful .
BACKGROUND Results of r and omised controlled trials ( RCTs ) of vitamin D supplementation to improve  bone density in children are inconsistent .
OBJECTIVES To determine the effectiveness of vitamin D supplementation for improving  bone mineral density in children , whether any effect varies by sex , age or pubertal stage , the type or dose of vitamin D given or baseline vitamin D status , and if effects persist after cessation of supplementation .
Effect of vitamin D supplementation on bone and vitamin D status among Pakistani immigrants in Denmark: a randomised double-blinded placebo-controlled intervention study.
Severe vitamin D deficiency is common among Muslim immigrants . The dose necessary to correct the deficiency and its consequence for bone health are not known for immigrants . The aim was to assess the effect of relatively low dosages of supplemental vitamin D on vitamin D and bone status in Pakistani immigrants . This 1-year-long r and omised double-blinded placebo-controlled intervention with vitamin D3 ( 10 and 20 microg/d ) included girls ( 10.1 - 14.7 years ) , women ( 18.1 - 52.7 years ) and men ( 17.9 - 63.5 years ) of Pakistani origin living in Denmark . The main endpoints were serum 25-hydroxyvitamin D ( S-25OHD ) , parathyroid hormone , bone turnover markers and bone mass . The study showed that supplementation with 10 and 20 microg vitamin D3 per d increased S-25OHD concentrations similarly in vitamin D-deficient Pakistani women ( 4-fold ) , and that 10 microg increased S-25OHD concentrations 2-fold and 20 microg 3-fold in Pakistani men . S-25OHD concentrations increased at 6 months and were stable thereafter . Baseline S-25OHD concentrations tended to be lower in girls and women than in men ; females achieved about 46 nmol/l and men 55 nmol/l after supplementation . Serum intact parathyroid hormone concentrations decreased at 6 months , but there was no significant effect of the intervention on bone turnover markers and dual-energy X-ray absorptiometry measurements of the whole body and lumbar spine
Vitamin D supplementation had no statistically significant effects on total body bone mineral content ( BMC ) , hip bone mineral density ( BMD ) or forearm BMD .
These results do not support vitamin D supplementation to improve bone density in healthy children with normal vitamin D levels , but suggest that supplementation of deficient children may be clinical ly useful .
BACKGROUND Results of r and omised controlled trials ( RCTs ) of vitamin D supplementation to improve  bone density in children are inconsistent .
OBJECTIVES To determine the effectiveness of vitamin D supplementation for improving  bone mineral density in children , whether any effect varies by sex , age or pubertal stage , the type or dose of vitamin D given or baseline vitamin D status , and if effects persist after cessation of supplementation .