Conclusions Our meta- analysis indicates that vitamin C may prevent post-operative atrial fibrillation in some countries outside of the USA , and it may also shorten the duration of hospital stay and ICU stay of cardiac surgery patients .
Vitamin C is an essential nutrient that is safe and inexpensive .
Background Atrial fibrillation ( AF ) , a common arrhythmia contributing substantially to cardiac morbidity , is associated with oxidative stress and , being an antioxidant , vitamin C might influence it .
Influence of intravenous vitamin E supplementation in cardiac surgery on oxidative stress: a double-blinded, randomized, controlled study.
BACKGROUND I.V. infusions of vitamin E emulsion ( all-rac-alpha-tocopherol ) may reduce ischaemia-reperfusion injury after elective cardiac surgery . METHODS Forty patients participated in a prospect i ve , double-blind , placebo-controlled , r and omized trial , receiving either placebo or four doses ( 270 mg each ) of all-rac-alpha-tocopherol between 16 h before and 48 h after surgery . We determined plasma concentrations of vitamin E , vitamin C , malondialdehyde , creatine kinase , troponin I and interleukin 6 and other measures of clinical outcome . RESULTS Infusion of vitamin E caused normalization of vitamin E plasma concentrations during and after surgery , but had no effect on the early increase in malondialdehyde concentration or the decreases in antioxidative capacity and the water-soluble antioxidant vitamin C. CONCLUSIONS Normalization of plasma vitamin E concentrations with parenteral vitamin E emulsion does not affect biochemical markers of myocardial injury and does not affect clinical outcome after cardiac surgery
Conclusions Our meta- analysis indicates that vitamin C may prevent post-operative atrial fibrillation in some countries outside of the USA , and it may also shorten the duration of hospital stay and ICU stay of cardiac surgery patients .
Vitamin C is an essential nutrient that is safe and inexpensive .
Background Atrial fibrillation ( AF ) , a common arrhythmia contributing substantially to cardiac morbidity , is associated with oxidative stress and , being an antioxidant , vitamin C might influence it .