Conclusion Various methods have been used at all stages of CSPBM development .
The choice between developing a classification system de novo or from an existing instrument may depend on the availability of a suitable existing measure , while the choice between a decomposed or composite approach appears to be determined primarily by the purpose for which the instrument is design ed .
Background Health state utility values ( HSUVs ) are required to calculate quality -adjusted life-years ( QALYs ) .
They are frequently derived from generic preference-based measures of health .
However , such generic measures may not capture health attributes of relevance to specific conditions .
In such cases , a condition-specific preference-based measure ( CSPBM ) may be more appropriate .
Objective This systematic review aim ed to identify all published accounts of developing CSPBMs to describe and appraise the methods used .
Psychometric evaluation of the National Eye Institute Visual Function Questionnaire and Visual Function Questionnaire Utility Index in patients with non-infectious intermediate and posterior uveitis
Objective To evaluate the psychometric properties of the National Eye Institute Visual Function Question naire-25 ( NEI VFQ-25 ) and Visual Function Question naire Utility Index ( VFQ-UI ) in patients with non-infectious intermediate and posterior uveitis . Methods Secondary analysis of pooled data from a 26-week , multicenter , masked , r and omized , sham-controlled Phase 3 clinical trial . Health-related quality of life was assessed using the NEI VFQ-25 , the EQ-5D , and SF-36 . Internal consistency reliability , reproducibility , convergent validity , and known groups of BCVA and vitreous haze severity were assessed . Clinical ly significant difference was assessed using anchor-based and distribution-based methods . Results The study included 224 subjects with non-infectious intermediate ( 80.4 % ) or posterior uveitis ( 19.6 % ) . The NEI VFQ-25 and the VFQ-UI demonstrated good internal consistency ( Cronbach ’s alpha 0.87–0.94 ) and test – retest reliability ( ICCs 0.58–0.88 ) . Spearman ’s product – moment rank correlations between the NEI VFQ-25  and VFQ-UI scores and the SF-6D , EQ-5D , and BCVA ranged from small to moderate . There was a significant association between visual functioning and known groups of visual acuity ( p < 0.05 ) . Clinical significance , using the anchor-based method ( difference between visual acuity groups ≥10–<15 letter better and no change ) , was 10.2 for change from baseline to week 26 for the NEI VFQ-25 composite score and 0.05 for the VFQ-UI . Using the distribution-based method , the clinical significance was 3.86 for the composite score and 0.04 for the VFQ-UI . Conclusion The NEI VFQ-25 and the VFQ-UI are reliable and valid measures of vision-related functioning and preference-based status in patients with non-infectious intermediate and posterior uveitis
Conclusion Various methods have been used at all stages of CSPBM development .
The choice between developing a classification system de novo or from an existing instrument may depend on the availability of a suitable existing measure , while the choice between a decomposed or composite approach appears to be determined primarily by the purpose for which the instrument is design ed .
Background Health state utility values ( HSUVs ) are required to calculate quality -adjusted life-years ( QALYs ) .
They are frequently derived from generic preference-based measures of health .
However , such generic measures may not capture health attributes of relevance to specific conditions .
In such cases , a condition-specific preference-based measure ( CSPBM ) may be more appropriate .
Objective This systematic review aim ed to identify all published accounts of developing CSPBMs to describe and appraise the methods used .