There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .
Increased arachidonic acid level in diabetic platelets following improvement in diabetic control.
A group of non-insulin dependent diabetics taking oral hypoglycaemic therapy  were studied to determine the effect of improved diabetic control on the platelet levels of the prostagl and in precursor fatty acids . The patients were r and omised to receive either a low carbohydrate diet ( 35 % of total energy ) for six weeks or a high carbohydrate diet ( 55 % of total energy ) , high fibre diet for six weeks and the diets were then reversed . At the end of the high carbohydrate , high fibre diet the mean fasting blood glucose ( 6.6 mmol section 1 ) and mean percentage glycosylated haemoglobin ( 8.2 % ) were significantly lower than after the low carbohydrate diet ( 7.8 . mmol/l , p less than 0.05 : 9.9 % , p less than 0.01 ) . Mean platelet phospholipid arachidonic acid percentage was significantly higher after the high carbohydrate , high fibre diet ( 24.2 % ) than after the low carbohydrate diet ( 19.9 % , p less than 0.01 ) . There were no significant changes in the other platelet fatty acids
There is low to high ( majority moderate ) certainty for small improvements of unclear clinical importance in plasma glucose , triglycerides , and HDL concentrations favoring low-carbohydrate food at half of the prespecified time points .
There was little to no difference in LDL concentration or any of the secondary outcomes ( body weight , waist circumference , blood pressure , quality of life ) in response to either of the diets ( very-low- to high-certainty evidence ) .
Conclusions Currently available data provide low- to moderate-certainty evidence that dietary carbohydrate restriction to a maximum of 40 % yields slightly better metabolic control of uncertain clinical importance than reduction in fat to a maximum of 30 % in people with T2D .
Background It remains uncertain which diet is best for people with type 2 diabetes ( T2D ) .
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on markers of metabolic syndrome and quality of life in people with T2D .