Grade B evidence also suggested that exercise may improve prostate cancer patients ' muscle mass , muscular strength , functional performance ( walking and sit to st and speed ) , as well as health-related , social and physical quality of life .
These effects appeared greater for group-rather than home-based-exercise , especially if these programs included resistance training .
CONTEXT Prostate cancer patients , especially those on and rogen deprivation therapy ( ADT ) , experience many symptoms that make it difficult to maintain their independence and quality of life .
Because ADT acts by means of reducing testosterone production , exercise may offset many of the ADT side effects and those of the cancer itself .
OBJECTIVES This systematic review of the literature evaluates whether exercise could reduce symptoms and improve quality of life for prostate cancer patients .
A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro.
BACKGROUND Prostate cancer is the most common solid-tumor cancer in US males but is rare in Asian males . When Asian men adopt the US lifestyle , clinical prostate cancer increases greatly . Epidemiological data from men in the US indicate that regular activity may reduce the risk for prostate cancer . METHODS Serum was obtained from  three groups of similar-aged men , Control , Diet and Exercise , and Exercise alone were used to stimulate LNCaP cells in culture .  Growth and apoptosis of tumor cells were measured . Serum sample s were also used to measure insulin , IGF-1 , IGFBP-1 . RESULTS The Diet and Exercise and the Exercise alone groups had lower serum insulin and IGF-1 but higher IGFBP-1 compared to Controls . LNCaP cell growth was reduced in both groups compared to Control and there was a major increase in apoptosis of tumor cells . CONCLUSIONS A low-fat diet and /or intensive exercise results in change in serum hormones and growth factors in vivo that can reduce growth and induce apoptosis of LNCaP prostate tumor cells in vitro
Grade B evidence also suggested that exercise may improve prostate cancer patients ' muscle mass , muscular strength , functional performance ( walking and sit to st and speed ) , as well as health-related , social and physical quality of life .
These effects appeared greater for group-rather than home-based-exercise , especially if these programs included resistance training .
CONTEXT Prostate cancer patients , especially those on and rogen deprivation therapy ( ADT ) , experience many symptoms that make it difficult to maintain their independence and quality of life .
Because ADT acts by means of reducing testosterone production , exercise may offset many of the ADT side effects and those of the cancer itself .
OBJECTIVES This systematic review of the literature evaluates whether exercise could reduce symptoms and improve quality of life for prostate cancer patients .