The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .
Studies on the effect of toothpaste rinses on plaque regrowth. (I). Influence of surfactants on chlorhexidine efficacy.
A number of compounds have been added to toothpastes to inhibit plaque regrowth . The inclusion of cationic antiseptics , such as chlorhexidine , poses formulation difficulties because of interactions with other ingredients particularly anionic detergents . More recently , Triclosan/zinc citrate formulations have been shown effective plaque inhibitors . The aim of this study was to compare a commercially available 0.2 % Triclosan/0.5 % zinc citrate toothpaste with a number of experimental 0.5 % chlorhexidine/detergent toothpastes for effects on plaque regrowth over 4 days . Subjects rendered plaque free at each baseline rinsed twice a day with toothpaste slurries and disclosed plaque was scored at the end of each period . All toothpastes significantly reduced plaque by comparison with a control toothpaste , but were significantly less effective than a 0.2 % chlorhexidine rinse . Some significant differences in favour of one chlorhexidine toothpaste were noted but these were small in magnitude . Whether the plaque inhibition obtained with Triclosan/zinc citrate toothpaste was greater than would be expected from other commercially available preparations can not be determined from this study and is the subject of a further investigation
The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .