The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride .
No difference was found when RM-GIC was compared with fluoride-containing composite resin .
RM-GIC showed efficacy in reducing demineralization .
UNLABELLED The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers ( RM-GIC ) , in comparison to fluoride-containing composite resin and composite resin without fluoride , are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge .
Evidence-based dentistry: Part IV. Research design and levels of evidence.
Previous papers in this series on evidence -based dentistry have discussed the first 2 steps in seeking answers to clinical problems formulating a clear question and strategically search ing for evidence . The next step , critical appraisal of the evidence , is made easier if one underst and s the basic concepts of clinical research design . The strongest design , especially for questions related to therapeutic or preventive interventions , is the r and omized , controlled trial . Questions relating to diagnosis , prognosis and causation are often studied with observational , rather than experimental , research design s. The strongest study design should be used whenever possible . Rules have been established to grade research evidence . This paper , the fourth in the series , presents an overview of research methodology most commonly used in the dental literature
The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride .
No difference was found when RM-GIC was compared with fluoride-containing composite resin .
RM-GIC showed efficacy in reducing demineralization .
UNLABELLED The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers ( RM-GIC ) , in comparison to fluoride-containing composite resin and composite resin without fluoride , are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge .