This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .
Comparison of fentanyl and nalbuphine in total intravenous anaesthesia (TIVA).
OBJECTIVE To compare Nalbuphine and fentanyl as total intravenous anaesthesia with propofol infusion in laproscopic cholecystectomy cases . STUDY DESIGN Double blind r and omised . METHODS Changes in haemodynamic variables greater than twenty percent above or below the baseline and recovery profile were observed . RESULTS Blood pressure remained within 20 % of baseline in either group . Nine patients in fentanyl and fifteen in nalbuphine group required an additional bolus of propofol intraoperatively . Heart rate response after tracheal intubation was significantly higher in the nalbuphine group ( 25 % ) . No difference was observed in the incidence of nausea and vomiting in the recovery room . Twenty-seven percent patients in the nalbuphine group required analgesia in the recovery in comparison to 87 % in the fentanyl group . Patients in the fentanyl group required analgesia earlier ( 37 minutes vs. 62 minutes ) . CONCLUSION Fentanyl provided better intraoperative haemodynamic stability in comparison to nalbuphine when used as the analgesic component in total intravenous anaesthesia with propofol . The recovery profile with both drugs was similar . Lesser number of patients required analgesia in the recovery in the nalbuphine group
This approach has been design ed to provide adequate analgesia while minimizing exposure to adverse events
Background : Laparoscopic cholecystectomy has advantages over the open procedure for postoperative pain .
However , a systematic review of postoperative pain management in this procedure has not been conducted .