This meta- analysis uncovered clinical ly improved effects of yoga intervention on glycemic control , lipid profiles and other parameters of T2DM management in prediabetic population .
These results suggest that yoga intervention may be considered as a comprehensive and alternative approach to preventing T2DM .
A systematic review and meta- analysis was conducted to investigate the effects of yoga on glycemic control , lipid profiles , body composition and blood pressure in people in the pre-diabetic state .
Hypothalamic arousal, insulin resistance and Type 2 diabetes mellitus.
AIMS Type 2 diabetes mellitus ( DM ) develops when insulin resistance overcomes the capacity of compensatory insulin secretion . Insulin resistance may be induced via psychoneuroendocrine pathways , a possibility which has received little previous attention . METHODS We have used salivary cortisol measurements to monitor the activity of the hypothalamic-pituitary-adrenal ( HPA ) axis , the major controller of hormones involved in the regulation of peripheral insulin sensitivity under everyday conditions . The influence of external challenges , as well as the sensitivity of feedback regulation , were followed in r and omly selected middle-aged population sample s. RESULTS In health there is a rhythmicity of cortisol secretion , with a high plasticity and efficient feedback control . In contrast , a group of subjects were identified with a flat , rigid day curve and poor feedback control , who showed consistent abnormalities in stress-related cortisol secretion , including inhibited secretions of sex steroids and growth hormone ; insulin resistance ; abdominal obesity ; elevated leptin levels ; hyperglycaemia ; dyslipidaemia and hypertension with elevated heart rate . The endocrine abnormalities are probably responsible for the anthropometric and metabolic abnormalities . The circulatory perturbations seem to be induced by a parallel activation of the central sympathetic nervous system suggesting an ' hypothalamic arousal syndrome ' , gradually developing into an independent risk for disease . An associated cluster of environmental factors , including psychosocial and socio-economic stress , traits of depression and anxiety , alcohol consumption and smoking , all factors known to activate hypothalamic centres , has been identified . A polymorphism of the glucocorticoid receptor gene , with 13.7 % homozygotes in the male Swedish population , parallels receptor dysfunction , and may be responsible for the associated insulin resistance , central obesity and hypertension . CONCLUSIONS This is the first detailed examination of psychoneuroendocrinological processes in the natural environment on a population basis in relation to somatic health . The results suggest that an hypothalamic arousal syndrome , with parallel activation of the HPA axis and the central sympathetic nervous system , is responsible for development of endocrine abnormalities , insulin resistance , central obesity , dyslipidaemia and hypertension , leading to frank disease , including Type 2 DM . We suggest that this syndrome is probably based on environmental pressures in genetically susceptible individuals
This meta- analysis uncovered clinical ly improved effects of yoga intervention on glycemic control , lipid profiles and other parameters of T2DM management in prediabetic population .
These results suggest that yoga intervention may be considered as a comprehensive and alternative approach to preventing T2DM .
A systematic review and meta- analysis was conducted to investigate the effects of yoga on glycemic control , lipid profiles , body composition and blood pressure in people in the pre-diabetic state .