Conclusion Probiotic supplementation seemed to be able to reduce the risk of a newborn 's hyperbilirubinemia and improve glycemic control , blood lipid profiles and inflammation and oxidative stress in pregnant women with GDM .
Background Previous studies showed that probiotics could improve glycemic control and attenuate some of the adverse effects of type 2 diabetes .
However , whether the effects are generalizable to gestational diabetes mellitus ( GDM ) remains uncertain .
Objective We conducted a systematic review and meta- analysis to evaluate the effects of probiotic supplement in GDM .
The Effect of Probiotic Yogurt on Constipation in Pregnant Women: A Randomized Controlled Clinical Trial
Background Probiotics can alter the colonic microbiota and might improve bowel function . Objectives The aim of this study was to evaluate the effect of the consumption of yogurt , enriched with Bifidobacterium and Lactobacillus 4.8 × 1010 ( CFU ) on the symptoms of constipated pregnant women . Material s and Methods This triple-blind r and omized controlled trial was conducted on 60 constipated pregnant women who were diagnosed by the ROME III criteria in Tabriz , Iran from December 2014 to July 2015 . Participants were r and omly put into two groups including the treatment and the control group through block r and omization . The treatment group received 300 g of yogurt enriched with Bifidobacterium and Lactobacillus 4.8 × 1010 colony forming units ( CFU ) ( n = 30 ) while the control group received conventional yogurt ( n = 30 ) for 4 weeks . The defecation frequency , stool consistency , straining during defecation , sensation of anorectal obstruction , sensation of incomplete evacuation and manual manoeuvres to facilitate defecation were primary outcomes while the amount of defecation , stool colure , and quality of life were secondary outcomes . Results The frequency of defecation was increased from 2.1 ( 0.8 ) at baseline to 8.3 ( 4.4 ) in the probiotic yogurt group vs. 2.3 ( 0.7 ) at baseline to 8.1 ( 4.3 ) in the conventional yogurt group at the end of 4th week . These results were based on the repeated measure ANOVA test and there was no statistically significant difference between the two groups ( mean difference : 0.1 ; Confidence Interval 95 % : -1.4 to 1.7 ; P = 0.872 ) . Constipation symptoms including straining , anorectal obstruction , manipulation to facilitate defecation , consistency of stool and color of stool were improved significantly ( P < 0.05 ) in both groups . In addition , the amount of defecation was significantly increased in both groups ( P < 0.05 ) , while incomplete evacuation was significantly reduced in the treatment group ( P = 0.01 ) . There was no statistically significant difference between the groups in the mean scores of physical ( P = 0.726 ) and mental ( P = 0.678 ) aspects of quality of life after the intervention with the adjusting of baseline scores . Conclusions Consumption of 300 g/day probiotic and conventional yogurt can play a role in improving the symptoms of constipation during pregnancy
Conclusion Probiotic supplementation seemed to be able to reduce the risk of a newborn 's hyperbilirubinemia and improve glycemic control , blood lipid profiles and inflammation and oxidative stress in pregnant women with GDM .
Background Previous studies showed that probiotics could improve glycemic control and attenuate some of the adverse effects of type 2 diabetes .
However , whether the effects are generalizable to gestational diabetes mellitus ( GDM ) remains uncertain .
Objective We conducted a systematic review and meta- analysis to evaluate the effects of probiotic supplement in GDM .