For total EE , correlation coefficients were statistically significantly lower in uniaxial compared to multisensor devices .
For active EE , correlations were slightly but not significantly lower in uniaxial compared to triaxial and multisensor devices .
The high level of heterogeneity in the validation studies is only partly explained by the type of activity monitor and the activity monitor outcome .
Triaxial and multisensor devices tend to be more valid monitors .
The assessment of physical activity in healthy population s and in those with chronic diseases is challenging .
The aim of this systematic review was to identify whether available activity monitors ( AM ) have been appropriately vali date d for use in assessing physical activity in these groups .
Six-Minute Walk Test and Cardiopulmonary Exercise Testing in Patients With Chronic Heart Failure: A Comparative Analysis on Clinical and Prognostic Insights
Background —The six-minute walk test ( 6MWT ) and cardiopulmonary exercise testing ( CPET ) are the 2 testing modalities most broadly used for assessing functional limitation in patients with heart failure ( HF ) . A comprehensive comparison on clinical and prognostic validity of the 2 techniques has not been performed and is the aim of the present investigation . Methods and Results —Two hundred fifty-three patients diagnosed with systolic ( n=211 ) or diastolic ( n=42 ) HF ( age : 61.9±10.1 years ; New York Heart Association Class : 2.2±0.78 ) underwent a 6MWT and a symptom-limited CPET evaluation and were prospect ively followed up . During the 4-year tracking period , there were 43 cardiac-related deaths with an annual cardiac mortality rate of 8.7 % . The 6MWT distance correlated with CPET-derived variables ( ie , peak Vo2 , Vo2 at anaerobic threshold , and Ve/Vco2 slope ) and was significantly reduced in proportion with lower peak Vo2 and higher Ve/Vco2 slope classes and presence of an exercise oscillatory breathing ( EOB ) pattern ( P<0.01 ) . However , no significant differences were observed in distance covered between survivors and nonsurvivors ( 353.2±95.8 m versus 338.5±76.4 m ; P = NS ) . At univariate and multivariate Cox proportional analyses , the association of the 6MWT distance with survival was not significant either as a continuous or dicotomized variable ( ≤300 m ) . Conversely , CPET-derived variables emerged as prognostic with the strongest association found for EOB ( systolic HF ) and Ve/Vco2 slope ( entire population with HF and patients with a 6MWT≤300 m ) . Conclusions —The 6MWT is confirmed to be a simple and reliable first-line test for quantification of exercise intolerance in patients with HF . However , there is no supportive evidence for its use as a prognostic marker in alternative to or in conjunction with CPET-derived variables
For total EE , correlation coefficients were statistically significantly lower in uniaxial compared to multisensor devices .
For active EE , correlations were slightly but not significantly lower in uniaxial compared to triaxial and multisensor devices .
The high level of heterogeneity in the validation studies is only partly explained by the type of activity monitor and the activity monitor outcome .
Triaxial and multisensor devices tend to be more valid monitors .
The assessment of physical activity in healthy population s and in those with chronic diseases is challenging .
The aim of this systematic review was to identify whether available activity monitors ( AM ) have been appropriately vali date d for use in assessing physical activity in these groups .