Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .
Alternate day fasting increases LDL particle size independently of dietary fat content in obese humans
Alternate day fasting ( ADF ) with a low-fat ( LF ) diet increases low-density lipoprotein ( LDL ) particle size . Whether these beneficial effects can be reproduced by a high-fat ( HF ) ADF diet is unclear . This study compared an ADF – HF to an ADF – LF diet on plasma lipids , LDL size and high-density lipoprotein ( HDL ) size .  Thirty-five obese subjects were r and omized to an ADF – HF or ADF – LF diet for 10 weeks . Body weight decreased ( P<0.0001 ) by 4.3±1.0 kg ( 4.8±1.1 % ) and 3.7±0.7 kg ( 4.2±0.8 % ) in the ADF – HF and ADF – LF group , respectively . LDL cholesterol was reduced ( P<0.0001 ) by 19±8 mg/dl ( 18±5 % ) by ADF – HF and 28±7 mg/dl ( 25±3 % ) by ADF – LF . LDL particle size increased ( P<0.005 ) by 3±1 Å in both groups . The proportion of small LDL particles decreased ( P<0.005 ) by 8±2 % and 11±3 % in the ADF – HF and ADF – LF groups , respectively . HDL cholesterol and HDL size remained unchanged . Thus , our results suggest that the ADF – HF diet is equally as effective as the ADF – LF diet in improving LDL particle size and distribution
Relative to a non-diet control , IF and ERD are effective for the improvement of circulating TC , LDL-C , and TG concentrations , but have no meaningful effects on HDL-C concentration .
The present results suggest that these dietary practice s are a means of enhancing the lipid profile in humans
OBJECTIVES To the best of our knowledge , no systematic review and meta- analysis has evaluated the cholesterol-lowering effects of intermittent fasting ( IF ) and energy-restricted diets ( ERD ) compared with control groups .
The aim of this review and meta- analysis was to summarize the effects of controlled clinical trials examining the influence of IF and ERD on lipid profiles .