Sensitivity analyses and meta-regression for hemoglobin suggested a higher response with lower trial quality ( suboptimal allocation concealment and blinding ) , use of condiments , and sodium iron edetate and a lower response when adults were included .
Consumption of iron-fortified foods results in an improvement in hemoglobin , serum ferritin , and iron nutriture and a reduced risk of remaining anemic and iron deficient
BACKGROUND The utility of iron fortification of food to improve iron deficiency , anemia , and biological outcomes is not proven unequivocally .
[Effectiveness of different iron supplementation strategies on hemoglobin and ferritin levels among schoolchildren in Teresina, Piauí State, Brazil].
This study evaluated the effectiveness of supplementation with ferrous sulfate and iron bis-glycinate chelate on hemoglobin and serum ferritin levels among schoolchildren ( 7 - 11 years ) of both sexes . A r and omized community-based trial including 138 anemic children ( hemoglobin < 11.5 g/dL ) was conducted in Teresina , Piauí State , Brazil . Children were assigned to two treatment groups on an individual basis . One group ( n = 71 ) received 40 mg iron as ferrous sulfate once weekly and the other group ( n = 67 ) received 3.8 mg of iron bis-glycinate chelate-enriched cookies , 3x/week , for 8 weeks . The interventions showed a significant increase ( p < 0.01 ) in hemoglobin levels ( 1.1g/dL ) for children who received ferrous sulfate and 0.9 g/dl in those who received iron bis-glycinate chelate , although not significant in the inter-group comparison ( p > 0.05 ) . No effect was observed on body iron for either intervention ( p > 0.05 ) . Children with depleted iron stores ( < 15 ng/mL ) at the beginning of interventions showed increased serum ferritin concentrations after 8 weeks ( p < 0.01 ) , although no difference between treatments ( p > 0.05 ) was observed . The results confirm the effectiveness of the iron supplementation interventions and corroborate the use of iron salts or ferrous bisglycinate chelate on a weekly basis to overcome iron deficiency and anemia
Sensitivity analyses and meta-regression for hemoglobin suggested a higher response with lower trial quality ( suboptimal allocation concealment and blinding ) , use of condiments , and sodium iron edetate and a lower response when adults were included .
Consumption of iron-fortified foods results in an improvement in hemoglobin , serum ferritin , and iron nutriture and a reduced risk of remaining anemic and iron deficient
BACKGROUND The utility of iron fortification of food to improve iron deficiency , anemia , and biological outcomes is not proven unequivocally .