Comparison of PO diets with diets rich in stearic acid , monounsaturated fatty acids ( MUFAs ) , and polyunsaturated fatty acids ( PUFAs ) showed significantly higher TC , LDL cholesterol , apolipoprotein B , HDL cholesterol , and apolipoprotein A-I , whereas most of the same biomarkers were significantly lower when compared with diets rich in myristic/lauric acid .
Comparison of PO-rich diets with diets rich in trans fatty acids showed significantly higher concentrations of HDL cholesterol and apolipoprotein A-I and significantly lower apolipoprotein B , triacylglycerols , and TC/HDL cholesterol .
Stratified and meta-regression analyses showed that the higher concentrations of TC and LDL cholesterol , when PO was substituted for MUFAs and PUFAs , were not significant in young people and in subjects with diets with a lower percentage of energy from fat .
Both favorable and unfavorable changes in CHD/CVD risk markers occurred when PO was substituted for the primary dietary fats , whereas only favorable changes occurred when PO was substituted for trans fatty acids .
BACKGROUND Palm oil ( PO ) may be an unhealthy fat because of its high saturated fatty acid content .
OBJECTIVE The objective was to assess the effect of substituting PO for other primary dietary fats on blood lipid-related markers of coronary heart disease ( CHD ) and cardiovascular disease ( CVD ) .
Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations.
BACKGROUND Structured lipids are being incorporated into foods to reduce their energy value . One such lipid is rich in stearic acid . OBJECTIVE The objective of this study was to compare the effects on plasma lipids of a stearic acid-rich triacylglycerol and a fat rich in palmitic acid in hypercholesterolemic subjects . DESIGN Fifteen subjects with an average plasma cholesterol concentration of 6.13 + /- 0.80 mmol/L initially ate a low-fat diet for 2 wk ( run-in period ) , followed in r and om order and blinded fashion by 2 high-fat diets ( for 5 wk each ) containing foods derived from margarines rich either in palmitic acid or in the structured , stearic acid-rich triacylglycerol . RESULTS Plasma cholesterol concentrations with the low-fat , the stearic acid-rich , and the palmitic acid-rich diets were not significantly different ( 5.35 + /- 0.83 , 5.41 + /- 0.78 , and 5.52 + /- 0.68 mmol/L , respectively ) but were significantly lower ( P < 0.001 ) than those measured during the habitual diet period ( ie , 2 wk before the study began ) . Neither HDL cholesterol nor plasma triacylglycerol differed significantly among the 3 study diets . CONCLUSION A similar increase in the intake of stearic and palmitic acids ( differing by approximately 5 % of total energy ) to ensure a high fat intake result ed in plasma total and LDL-cholesterol concentrations that did not differ significantly from concentrations measured during a period of low-fat intake
Comparison of PO diets with diets rich in stearic acid , monounsaturated fatty acids ( MUFAs ) , and polyunsaturated fatty acids ( PUFAs ) showed significantly higher TC , LDL cholesterol , apolipoprotein B , HDL cholesterol , and apolipoprotein A-I , whereas most of the same biomarkers were significantly lower when compared with diets rich in myristic/lauric acid .
Comparison of PO-rich diets with diets rich in trans fatty acids showed significantly higher concentrations of HDL cholesterol and apolipoprotein A-I and significantly lower apolipoprotein B , triacylglycerols , and TC/HDL cholesterol .
Stratified and meta-regression analyses showed that the higher concentrations of TC and LDL cholesterol , when PO was substituted for MUFAs and PUFAs , were not significant in young people and in subjects with diets with a lower percentage of energy from fat .
Both favorable and unfavorable changes in CHD/CVD risk markers occurred when PO was substituted for the primary dietary fats , whereas only favorable changes occurred when PO was substituted for trans fatty acids .
BACKGROUND Palm oil ( PO ) may be an unhealthy fat because of its high saturated fatty acid content .
OBJECTIVE The objective was to assess the effect of substituting PO for other primary dietary fats on blood lipid-related markers of coronary heart disease ( CHD ) and cardiovascular disease ( CVD ) .