None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .
Effects of glucose-insulin-potassium infusion on myocardial perfusion and left ventricular remodeling in patients treated with primary angioplasty for ST-elevation acute myocardial infarction.
The role of glucose-insulin-potassium ( GIK ) infusion in the management of  acute coronary syndrome  is controversial . Limited data are available on the effects of adjunctive high-dose GIK ( 30 % glucose , 50 IU of insulin , 80 mEq of potassium chloride infused at 1.5 ml/kg/hour over 24 hours ) on myocardial perfusion and left ventricular ( LV ) remodeling in patients treated with primary percutaneous coronary intervention ( PCI ) for ST-segment elevation myocardial infa rct ion . In this prospect i ve study , 73 patients were r and omized to receive GIK infusion ( n = 40 ) or saline ( placebo , n = 33 ) in addition to st and ard therapy . The primary end points were myocardial perfusion after PCI and LV remodeling at 6 months . Thrombolysis In Myocardial Infa rct ion frame count and myocardial blush grade were evaluated before and after reperfusion treatment . LV end-diastolic and end-systolic volumes , ejection fraction , and wall motion score index were assessed in each patient after PCI and after 6 months . Although no differences in final Thrombolysis In Myocardial Infa rct ion flow were observed between the 2 groups , myocardial blush grade 3 was more frequently achieved in the GIK group ( p < 0.05 ) . At 6 months , ventricular remodeling was more often observed in the control group ( 24 % vs 3 % , p < 0.05 ) . In conclusion , GIK infusion in adjunct to primary PCI in patients with ST-segment elevation myocardial infa rct ion was safe , improved myocardial perfusion after revascularization , and was associated with less LV remodeling at follow-up
None of the trials examined the effects of the interventions in terms of costs .
AUTHORS ' CONCLUSIONS The included trials did not demonstrate significant differences for most of the outcomes when targeting intensive perioperative glycaemic control compared with conventional glycaemic control in patients with diabetes mellitus .
However , posthoc analysis indicated that intensive glycaemic control was associated with an increased number of patients experiencing hypoglycaemic episodes .
BACKGROUND Patients with diabetes mellitus are at increased risk of postoperative complications .
Data from r and omised clinical trials and meta-analyses point to a potential benefit of intensive glycaemic control , targeting near-normal blood glucose , in patients with hyperglycaemia ( with and without diabetes mellitus ) being su bmi tted to surgical procedures .
However , there is limited evidence concerning this question in patients with diabetes mellitus undergoing surgery .
OBJECTIVES To assess the effects of perioperative glycaemic control for diabetic patients undergoing surgery .