Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .
Effect of high dose vitamin C supplementation on muscle soreness, damage, function, and oxidative stress to eccentric exercise.
This study investigated if vitamin C supplementation before and after eccentric exercise could reduce  muscle soreness ( MS ) , oxidative stress , and muscle function .  Eighteen healthy men r and omly assigned to either a placebo ( P ) or vitamin C ( VC ) ( 3 g/d ) treatment group took pills for 2 wk prior and 4 d after performing 70 eccentric elbow extensions with their non-dominant arm . MS increased in both groups with significantly reduced MS for the first 24 h with VC . Range of motion was reduced equally in both groups after the exercise ( P > or = 0.05 ) . Muscle force declined equally and was unaffected by treatment . VC attenuated the creatine kinase ( CK ) increase at 48 h after exercise with similar CK after this time . Glutathione ratio ( oxidized glutathione/total glutathione ) was significantly increased at 4 and 24 h with P but VC prevented this change . These data suggest that vitamin C pretreatment can reduce MS , delay CK increase , and prevent blood glutathione oxidation with little influence on muscle function loss
Conclusion Overall , our findings do not support the presence of a secondary loss of strength following an acute muscle injury , and strongly suggest that strength , on average , recovers steadily over the first 3 days post-injury
Background An immediate loss of strength follows virtually all types of muscle injury but there is debate whether the initial strength loss is maximal or if a secondary loss of strength occurs during the first 3 days post-injury .
Objective The objective of this analysis was to conduct a systematic review and meta- analysis of the research literature to determine if a secondary loss of strength occurs after an injurious initiating event .