Among the outcomes examined , the highest absolute risk increase was for heart failure .
Associations between atrial fibrillation and included outcomes were broadly consistent across subgroups and in sensitivity analyses .
Atrial fibrillation is associated with an increased risk of death and an increased risk of cardiovascular and renal disease .
OBJECTIVE To quantify the association between  atrial fibrillation and cardiovascular disease , renal disease , and death .
Prognosis of congestive heart failure after prior myocardial infarction in older persons with atrial fibrillation versus sinus rhythm.
In a prospect i ve study of 651 older persons with congestive heart failure after prior myocardial infa rct ion , persons with atrial fibrillation had a significantly higher mortality than those with sinus rhythm if they had an abnormal ( p = 0.005 ) or normal ( p = 0.0001 ) left ventricular ejection fraction . The Cox regression model showed that significant independent risk factors for total mortality were age ( risk ratio 1.03 for an increment of 1 year of age ) , hypertension ( risk ratio 1.2 ) , diabetes mellitus ( risk ratio 1.4 ) , abnormal left ventricular ejection fraction ( risk ratio 2.1 ) , and atrial fibrillation ( risk ratio 1.5 )
Among the outcomes examined , the highest absolute risk increase was for heart failure .
Associations between atrial fibrillation and included outcomes were broadly consistent across subgroups and in sensitivity analyses .
Atrial fibrillation is associated with an increased risk of death and an increased risk of cardiovascular and renal disease .
OBJECTIVE To quantify the association between  atrial fibrillation and cardiovascular disease , renal disease , and death .