Following intervention , there was certain and significant improvement of metabolic state for metabolically abnormal obesity ( MAO ) subjects .
Only diastolic blood pressure had reduced for MHO individuals after intervention .
Conclusions : Almost one-third of the obese individuals are in metabolic health .
However , they are still at higher risk of advancing to unhealthy state .
Background : We conducted a systematic review and meta- analysis to firstly obtain a reliable estimation of the prevalence of metabolically healthy obese ( MHO ) individuals in obesity , then assessed the risk of developing metabolic abnormalities ( MA ) among MHO individuals .
At last , we evaluated the effects of traditional lifestyle interventions on metabolic level for MHO subjects .
Weight loss on low-fat vs. low-carbohydrate diets by insulin resistance status among overweight adults and adults with obesity: A randomized pilot trial.
OBJECTIVE To test for differential weight loss response to low-fat ( LF ) vs. low-carbohydrate ( LC ) diets by insulin resistance status with emphasis on overall quality of both diets . METHODS Sixty-one adults , BMI 28 - 40 kg/m(2 ) , were r and omized in a 2 × 2 design to LF or LC by insulin resistance status in this pilot study . Primary outcome was 6-month weight change . Participants were characterized as more insulin resistant ( IR ) or more insulin sensitive ( IS ) by median split of baseline insulin-area-under-the-curve from an oral glucose tolerance test . Intervention consisted of 14 one-hour class-based educational sessions . RESULTS Baseline % carbohydrate:% fat:% protein was 44:38:18 . At 6 months , the LF group reported 57:21:22 and the LC group reported 22:53:25 ( IR and IS combined ) . Six-month weight loss ( kg ) was 7.4 ± 6.0 ( LF-IR ) , 10.4 ± 7.8 ( LF-IS ) , 9.6 ± 6.6 ( LC-IR ) , and 8.6 ± 5.6 ( LC-IS ) . No significant main effects were detected for weight loss by diet group or IR status ; there was no significant diet × IR interaction . Significant differences in several secondary outcomes were observed . CONCLUSIONS Substantial weight loss was achieved overall , but a significant diet × IR status interaction was not observed . Opportunity to detect differential response may have been limited by the focus on high diet quality for both diet groups and sample size
Following intervention , there was certain and significant improvement of metabolic state for metabolically abnormal obesity ( MAO ) subjects .
Only diastolic blood pressure had reduced for MHO individuals after intervention .
Conclusions : Almost one-third of the obese individuals are in metabolic health .
However , they are still at higher risk of advancing to unhealthy state .
Background : We conducted a systematic review and meta- analysis to firstly obtain a reliable estimation of the prevalence of metabolically healthy obese ( MHO ) individuals in obesity , then assessed the risk of developing metabolic abnormalities ( MA ) among MHO individuals .
At last , we evaluated the effects of traditional lifestyle interventions on metabolic level for MHO subjects .