A systematic evaluation of the available evidence suggests similarities as well as important differences in the risk factors for incidence of AF as compared with other cardiovascular diseases , which has implication s for the primary prevention strategies for atrial fibrillation
Established primary prevention strategies of cardiovascular diseases are based on underst and ing of risk factors , but whether the same risk factors are associated with  atrial fibrillation ( AF )  remains unclear .
Psoriasis and risk of atrial fibrillation and ischaemic stroke: a Danish Nationwide Cohort Study.
AIMS Psoriasis is a chronic inflammatory disease and inflammation contributes to the pathogenesis of  atrial fibrillation ( AF ) and ischaemic stroke . We therefore investigated the risk of these endpoints in patients with psoriasis . METHODS AND RESULTS Cohort study of the entire Danish population followed from 1997 to 2006 by individual-level-linkage of nationwide prospect ively recorded registers . Multivariable Poisson 's regression and sensitivity analyses were used to assess the psoriasis-related risk of AF and ischaemic stroke .  A total of 36 765 patients with mild psoriasis and 2793 with severe psoriasis were compared with 4 478 926 individuals , i.e. , the reference population . In patients with mild psoriasis , the adjusted rate ratios ( RRs ) for AF were 1.50 ( 1.21 - 1.86 ) and 1.16 ( 1.08 - 1.24 ) in patients aged < 50 and ≥50 years , respectively . Patients with severe psoriasis had a higher risk of AF with RRs 2.98 ( 1.80 - 4.92 ) in patients aged < 50 years and 1.29 ( 1.01 - 1.65 ) in patients aged ≥50 years . Patients with psoriasis also demonstrated a disease severity-dependent increased risk of ischaemic stroke , i.e. RRs 1.97 ( 1.66 - 2.34 ) and 2.80 ( 1.81 - 4.34 ) in patients aged < 50 years with mild and severe psoriasis , and RRs 1.13 ( 1.04 - 1.21 ) and 1.34 ( 1.04 - 1.71 ) in patients aged ≥50 years with mild and severe psoriasis , respectively . A range of sensitivity analyses yielded comparable results . CONCLUSION Psoriasis is associated with increased risk of AF and ischaemic stroke . These novel results add to a growing body of evidence , suggesting that patients with psoriasis could be considered at increased cardiovascular risk
A systematic evaluation of the available evidence suggests similarities as well as important differences in the risk factors for incidence of AF as compared with other cardiovascular diseases , which has implication s for the primary prevention strategies for atrial fibrillation
Established primary prevention strategies of cardiovascular diseases are based on underst and ing of risk factors , but whether the same risk factors are associated with  atrial fibrillation ( AF )  remains unclear .