This review found no clear or consistent evidence that genetic risk communication alone either raises motivation or translates into actual change in dietary intake or physical activity to reduce the risk of cardiometabolic disorders in adults .
Genetic risk prediction of chronic conditions including obesity , diabetes and CVD currently has limited predictive power but its potential to engage healthy behaviour change has been of immense research interest .
We aim ed to underst and whether the latter is indeed true by conducting a systematic review and meta- analysis investigating whether genetic risk communication affects motivation and actual behaviour change towards preventative lifestyle modification .
Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries
Abstract Improving lifestyle behaviours has considerable potential for reducing the global burden of non-communicable diseases , promoting better health across the life-course and increasing well-being . However , realising this potential will require the development , testing and implementation of much more effective behaviour change interventions than are used conventionally . Therefore , the aim of this study was to conduct a multi-centre , web-based , proof-of-principle study of personalised nutrition ( PN ) to determine whether providing more personalised dietary advice leads to greater improvements in eating patterns and health outcomes compared to conventional population -based advice . A total of 5,562 volunteers were screened across seven European countries ; the first 1,607 participants who fulfilled the inclusion criteria were recruited into the trial . Participants were r and omly assigned to one of the following intervention groups for a 6-month period : Level 0—control group — receiving conventional , non-PN advice ; Level 1—receiving PN advice based on dietary intake data alone ; Level 2—receiving PN advice based on dietary intake and phenotypic data ; and Level 3—receiving PN advice based on dietary intake , phenotypic and genotypic data . A total of 1,607 participants had a mean age of 39.8 years ( ranging from 18 to 79 years ) . Of these participants , 60.9 % were women and 96.7 % were from white-European background .  The mean BMI for all r and omised participants was 25.5 kg m−2 , and 44.8 % of the participants had a BMI ≥ 25.0 kg m−2 . Food4Me is the first large multi-centre RCT of web-based PN . The main outcomes from the Food4Me study will be su bmi tted for publication during 2015
This review found no clear or consistent evidence that genetic risk communication alone either raises motivation or translates into actual change in dietary intake or physical activity to reduce the risk of cardiometabolic disorders in adults .
Genetic risk prediction of chronic conditions including obesity , diabetes and CVD currently has limited predictive power but its potential to engage healthy behaviour change has been of immense research interest .
We aim ed to underst and whether the latter is indeed true by conducting a systematic review and meta- analysis investigating whether genetic risk communication affects motivation and actual behaviour change towards preventative lifestyle modification .