Specific recommendations for implantation of each prosthesis , taking into consideration the presence of pre-existent conduction abnormalities and anatomical factors , may be needed to reduce the risk of PPI
Aims The incidence of new-onset conduction abnormalities requiring permanent pacemaker implantation ( PPI ) after transcatheter aortic valve implantation ( TAVI ) with new-generation prostheses remains debated .
This systematic review analyses the incidence of PPI after TAVI  with new-generation devices and evaluates the electrical , anatomical , and procedural factors associated with PPI .
In addition , the incidence of PPI after  TAVI with early generation prostheses was review ed for comparison .
Permanent pacemaker implantation after transapical transcatheter aortic valve implantation.
The aim of the study was to determine the incidence of permanent pacemaker implantation ( PPMI ) in a cohort of 358 patients undergoing transapical aortic valve implantation ( TAVI ) using a balloon-exp and able prosthesis between April 2008 and March 2011 . After excluding patients who had had a previous PPMI ( n=36 ; 10 % ) , the study group consisted of 322 patients . These were divided into two groups : patients who required PPMI ( PPM group ) and patients who did not require it ( non-PPM group ) . Preoperative , perioperative and one-year follow-up data were collected prospect ively . Twenty ( 6.2 % ) patients required PPMI . Previous implantation of an aortic prosthesis ( P = non-significant ) , previous coronary artery bypass grafting ( P=0.05 ) and coronary artery disease ( P<0.005 ) were more common in the non-PPM group . On logistic regression , only patient age seemed to be correlated to PPMI ( P=0.05 , odds ratio 1.08 ; CI 0.9 - 1.1 ) . There was no difference in survival rate between the groups after 30 days ( PPM group 95 % , non-PPM group 93.6 % ) . Similarly , the survival rate did not differ after one year ( PPM group 84 % , non-PPM group 80.9 % ; P=0.3 ) . The PPMI rate after transapical TAVI using a balloon-exp and able prosthesis is thus low , and has no impact on early and follow-up mortality
Specific recommendations for implantation of each prosthesis , taking into consideration the presence of pre-existent conduction abnormalities and anatomical factors , may be needed to reduce the risk of PPI
Aims The incidence of new-onset conduction abnormalities requiring permanent pacemaker implantation ( PPI ) after transcatheter aortic valve implantation ( TAVI ) with new-generation prostheses remains debated .
This systematic review analyses the incidence of PPI after TAVI  with new-generation devices and evaluates the electrical , anatomical , and procedural factors associated with PPI .
In addition , the incidence of PPI after  TAVI with early generation prostheses was review ed for comparison .