Evidence suggests significant improvement in obesity-hypertension in patients who undergo surgical weight-reduction procedures .
Malabsorptive techniques such as the Roux-en-Y gastric bypass or surgical resection techniques such as laparoscopic sleeve gastrectomy appear to offer superior results in regards to hypertension control over restrictive techniques such as Gastric B and ing .
Though long-term control of hypertension following surgery remains a concern , available follow-up post-operative data of up to 10 years suggests a sustained , if lessened , effect on hypertension control over time
Obesity continues to increase in prevalence worldwide .
Hypertension has long been associated with obesity , and weight loss continues to be a first-line therapy in the treatment of hypertension .
Lifestyle modification and pharmacologic therapy , however , often meet with treatment failure .
Bariatric surgery continues to be the most successful approach to sustained weight loss .
This review focuses on the underlying physiologic mechanisms of obesity-hypertension , and the impact of bariatric surgery on the treatment of hypertension .
A Preliminary Observation of Weight Loss Following Left Gastric Artery Embolization in Humans
Background / Objectives . Embolization of the left gastric artery ( LGA ) , which preferentially supplies the gastric fundus , has been shown to produce weight loss in animal models . However , weight loss after LGA embolization in humans has not been previously established . The aim of this study was to evaluate postprocedural weight loss in patients following LGA embolization .  Subjects/ Methods . A retrospective analysis of the medical records of patients who underwent LGA embolization for upper gastrointestinal ( GI ) bleeding was performed . Postprocedural weight loss in this group was compared to a control group of patients who had undergone embolization of other arteries for upper GI bleeding . Results . The experimental group ( N = 19 ) lost an average of 7.3 % of their initial body weight within three months of LGA embolization , which was significantly greater than the 2 % weight loss observed in the control group ( N = 28 ) ( P = 0.006 ) . No significant differences were seen between the groups in preprocedural body mass index ( BMI ) , age , postprocedural care in the intensive care unit , history of malignancy , serum creatinine , or left ventricular ejection fraction . Conclusions . The current data suggest that body weight in humans may be modulated via LGA embolization . Continued research is warranted with prospect i ve studies to further investigate this phenomenon
Evidence suggests significant improvement in obesity-hypertension in patients who undergo surgical weight-reduction procedures .
Malabsorptive techniques such as the Roux-en-Y gastric bypass or surgical resection techniques such as laparoscopic sleeve gastrectomy appear to offer superior results in regards to hypertension control over restrictive techniques such as Gastric B and ing .
Though long-term control of hypertension following surgery remains a concern , available follow-up post-operative data of up to 10 years suggests a sustained , if lessened , effect on hypertension control over time
Obesity continues to increase in prevalence worldwide .
Hypertension has long been associated with obesity , and weight loss continues to be a first-line therapy in the treatment of hypertension .
Lifestyle modification and pharmacologic therapy , however , often meet with treatment failure .
Bariatric surgery continues to be the most successful approach to sustained weight loss .
This review focuses on the underlying physiologic mechanisms of obesity-hypertension , and the impact of bariatric surgery on the treatment of hypertension .