Benefits , harms , and costs Guideline implementation should result in a reduction of cost and related harm of administering antibiotics when not required and a reduction of infection and related morbidities when antibiotics have demonstrated a proven benefit .
Abstract Objective To review the evidence and provide recommendations on antibiotic prophylaxis for gynaecologic procedures .
Outcomes Outcomes evaluated include need and effectiveness of antibiotics to prevent infections in gynaecologic procedures .
A prospective randomised study of the effects of prophylactic antibiotics on the incidence of bacteraemia following hysteroscopic surgery.
OBJECTIVE To study the effect of prophylactic antibiotics on the incidence of bacteraemia following hysteroscopic surgery . DESIGN Prospect i ve r and omized study . SETTING Aberdeen Royal Infirmary . SUBJECTS One hundred and sixteen women about to undergo either endometrial laser ablation ( ELA ) or transcervical resection of the endometrium ( TCRE ) . INTERVENTION Fifty-five women were r and omised to receive 1.2 g of Augmentin ( co-amoxiclav ) i.v . at induction of anaesthesia . Sixty-one women received no antibiotic prophylaxis .  Blood cultures were obtained at the end of the surgical procedure . RESULTS Incidence of bacteraemia in the non-antibiotic group ( 16 % ) was significantly higher than that in the antibiotic group ( 2 % ) ( 95 % confidence interval for difference from 5 % to 25 % ) . The majority of organisms were of dubious clinical significance and contamination could not be excluded in 7 cases out of 10 . CONCLUSION There is no convincing evidence that antibiotics are of value in this clinical setting
Benefits , harms , and costs Guideline implementation should result in a reduction of cost and related harm of administering antibiotics when not required and a reduction of infection and related morbidities when antibiotics have demonstrated a proven benefit .
Abstract Objective To review the evidence and provide recommendations on antibiotic prophylaxis for gynaecologic procedures .
Outcomes Outcomes evaluated include need and effectiveness of antibiotics to prevent infections in gynaecologic procedures .