In conclusion , bariatric surgery is associated with a reduction in specific adipokines including leptin , chemerin , and PAI-1 , whereas adiponectin is raised , adaptations that could be indicative of improved fat mass and function
Different adipokines secreted from adipose tissue , exert a range of physiological effects .
The aim of present systematic review and meta- analysis was to critically investigate the consequence of  bariatric surgery on circulating adipokines , that is , adiponectin , leptin , visfatin , resistin , plasminogen activator inhibitor , and chemerin .
Energy economy hampers body weight loss after gastric bypass.
The impact of energy economy on body weight loss was investigated in 20 obese women , su bmi tted to Roux-en-Y gastric bypass .  Resting energy expenditure ( REE ) , substrate oxidation rates , plasma glucose , free fatty acid , and insulin and leptin levels were measured before and 3 , 6 , and 12 months after surgery . Predicted REE was obtained from linear regression analysis of REE and fat free mass , in a group of 85 women , whose body mass index ranged between 20 and 60 kg/m(2 ) . The deviation from predicted REE , calculated as area under the curve ( AUC ) over the 12-month period for each patient , was considered as the expression of energy economy . Energy economy AUC was significantly ( P : < 0.005 ) negatively related to the weight lost during 12 months after surgery . Energy intake , calculated from self-reported food consumption , was also expressed as AUC . Energy intake AUC showed a significant ( P : < 0.002 ) positive correlation with weight loss . Lipid oxidation rate , also calculated as AUC , significantly correlated , negatively , with energy economy ( P : < 0 . 001 ) and , positively , with energy intake ( P : < 0.002 ) . Preoperative leptin values were significantly ( P : < 0.01 ) linked to individual energy economy capacity . In conclusion , after Roux-en-Y gastric bypass , energy economy hampers the weight loss process , probably through a low fat oxidation rate
In conclusion , bariatric surgery is associated with a reduction in specific adipokines including leptin , chemerin , and PAI-1 , whereas adiponectin is raised , adaptations that could be indicative of improved fat mass and function
Different adipokines secreted from adipose tissue , exert a range of physiological effects .
The aim of present systematic review and meta- analysis was to critically investigate the consequence of  bariatric surgery on circulating adipokines , that is , adiponectin , leptin , visfatin , resistin , plasminogen activator inhibitor , and chemerin .