INTERPRETATION There was a clinical ly relevant association between early migration of TKPs and late revision for loosening .
PURPOSE We performed two parallel systematic review s and meta-analyses to determine the association between early migration of tibial components and late aseptic revision .
[What effect does the hydroxyapatite coating have in cementless knee arthroplasty?].
The goal of this study was to compare the migration of  noncemented diffusion sintered titanium fibermesh-coated tibial components with ( HA group ) and without ( non-HA group ) additional hydroxyapatite coating .  For this purpose  digital radiostereometry ( DIRSA ) was used to compare the migration after 2 and 9 years for the two groups . After 2 years the mean maximum subsidence of the HA-coated components ( 0.24+/-0.18 mm ) was about one-half of the mean maximum subsidence of the non-HA-coated group ( 0.55+/-0.55 mm ) . After 9 years the maximum subsidence of the HA-coated components was still smaller , but not as pronounced as before . The same trend was also found for the endpoint maximum total point motion ( MTPM ) . After 2 years the mean MTPM of the HA-coated components was 0.66+/-0.38 mm and of the non-HA group 0.73+/-0.50 mm . After 9 years the mean MTPM for the HA-coated components was 0.54+/-0.15 mm and for the non-HA-coated components 0.74+/-0.20 mm . None of the HA-coated tibial components but one of the non-HA group had to be revised and exchanged due to aseptic loosening
INTERPRETATION There was a clinical ly relevant association between early migration of TKPs and late revision for loosening .
PURPOSE We performed two parallel systematic review s and meta-analyses to determine the association between early migration of tibial components and late aseptic revision .