The results of this systematic review indicate that the dietary supplementation with red yeast rice , bergamot , artichoke , and virgin olive oil has promising effects on the increase of HDL-C serum levels .
The artichoke leaf extract and virgin olive oil appear to be particularly interesting , while bergamot extract needs further research and the effect of red yeast rice seems to be limited to patients with previous myocardial infa rct ion .
Various MediterrAsian diet products or natural extracts may represent a potential intervention treatment to raise HDL-C in dyslipidemic subjects
Background .
High HDL-cholesterol ( HDL-C ) values are negatively correlated with cardiovascular diseases .
This review analyses the effect of the supplementation with various Mediterranean diet products ( artichoke , bergamot , and olive oil ) and Asian diet products ( red yeast rice ) on the  HDL-C value in dyslipidemic subjects .
Effect of lovastatin on cardiovascular resource utilization and costs in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). AFCAPS/TexCAPS Research Group.
This cost-consequences analysis of the Air Force/Texas Coronary Atherosclerosis Prevention Study compares the costs of lovastatin treatment with the costs of cardiovascular hospitalizations and procedures . The cost of lovastatin treatment was defined as the average retail price and the cost of drug safety monitoring and adverse experiences . Costs were determined by actual rates of hospitalizations and procedures . Within a trial , lovastatin treatment cost approximately $ 4,654/patient . Lovastatin treatment significantly reduced the cumulative rate of cardiovascular hospitalizations and procedures ( p = 0.002 ) . Over the duration of the study , the cumulative number of cardiovascular hospitalizations and related therapeutic procedures was significantly reduced by 29 % . The time to first cardiovascular-related hospitalization or procedure was significantly extended by lovastatin ( p = 0.002 ) . Lovastatin reduced the frequency of cardiovascular hospitalization ( 28 % ) , and cardiovascular therapeutic ( 32 % ) and diagnostic procedures ( 23 % ) . Among therapeutic procedures , treatment reduced coronary artery bypass graft surgery by 19 % and percutaneous transluminal coronary angioplasty by 37 % . Total cardiovascular-related hospital days were reduced by 26 % ( p = 0.025 ) . The between-group offset in direct medical costs was $ 524 , which result ed in a 11 % cost offset of lovastatin therapy over the mean study duration of 5.2 years . Lovastatin provides meaningful reductions in cardiovascular-related re source utilization and reductions in direct cardiovascular-related costs associated with the onset of coronary disease
The results of this systematic review indicate that the dietary supplementation with red yeast rice , bergamot , artichoke , and virgin olive oil has promising effects on the increase of HDL-C serum levels .
The artichoke leaf extract and virgin olive oil appear to be particularly interesting , while bergamot extract needs further research and the effect of red yeast rice seems to be limited to patients with previous myocardial infa rct ion .
Various MediterrAsian diet products or natural extracts may represent a potential intervention treatment to raise HDL-C in dyslipidemic subjects
Background .
High HDL-cholesterol ( HDL-C ) values are negatively correlated with cardiovascular diseases .
This review analyses the effect of the supplementation with various Mediterranean diet products ( artichoke , bergamot , and olive oil ) and Asian diet products ( red yeast rice ) on the  HDL-C value in dyslipidemic subjects .