Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .
Is sensory testing during lead placement crucial for achieving positive outcomes after sacral neuromodulation?
AIMS Motor and sensory responses help guide lead placement during staged neuromodulation procedures . However , eliciting sensory responses requires lighter anesthesia . We evaluated the impact of assessing sensory responses during quadripolar tined lead placement on outcomes in subjects with refractory voiding symptoms . METHODS Adults who had a sacral lead placed were identified from our prospect i ve neuromodulation data base and grouped by whether they had intraoperative sensory testing  or not  .  History , operative data , and implantable permanent generator ( IPG ) implant , lead revision and device explant rates were collected from medical records . Symptoms were evaluated with the Interstitial Cystitis Symptom Index/Problem Index ( ICSI-PI ) and scaled global response assessment s ( GRA ) for the first 24 months post IPG placement . Data were analyzed using Pearson 's Chi-square , Fisher 's Exact , or Wilcoxon rank test . RESULTS Of 141 subjects ( 82 % female ) , 86 ( 61 % ) had sensory testing and 55 ( 39 % ) did not .  Sensory and no sensory testing groups were not significantly different on demographics , urologic diagnosis , IPG implant rates ( 76/84 ; 90 % and 48/55 ; 87 % respectively ) or mean operative time ( 37.9 ± 13.9 minutes vs. 35.5 ± 11.6 ) . Within 4 years , 19/141 ( 13.5 % ) were revised and /or explanted . For explant alone , 11/86 ( 13 % ) in the sensory and only 3/55 ( 5.5 % ) in the no sensory group ( P = 0.16 ) were explanted . Overall , ICSI-PI scores improved over time ( P < 0.0001 ) and most reported improvement on the GRA at each time point , but no differences were seen between groups . CONCLUSIONS Intraoperative sensory testing during sacral lead placement does not necessarily improve IPG implantation rates or clinical outcomes of neuromodulation
Pelvic floor exercises are more effective in subjective and objective outcomes with biofeedback or verbal feedback .
Weight loss with diet and exercise , caffeine reduction , 25 - 50 % reduction in fluid intake , and pelvic floor muscle exercises with verbal instruction and or biofeedback were all efficacious .
Botulinum toxin A improves urge incontinence episodes , urgency , frequency , quality of life , nocturia , and urodynamic testing parameters .
Acupuncture  improves quality of life and urodynamic testing parameters .
Extracorporeal magnetic stimulation improves urodynamic parameters .
Mirabegron improves daily incontinence episodes , nocturia , number of daily voids , and urine volume per void , whereas solabegron improves daily incontinence episodes .
Short-term posterior tibial nerve stimulation is more efficacious than pelvic floor muscle training exercises and behavioral therapy for improving : urgency , urinary incontinence episodes , daily voids , volume per void , and overall quality of life .
Sacral neuromodulation is more efficacious than antimuscarinic treatment for subjective improvement of overactive bladder and quality of life .
Transvaginal electrical stimulation demonstrates subjective improvement in overactive bladder symptoms and urodynamic parameters .
Multiple therapies , including physical therapy , behavioral therapy , botulinum toxin A , acupuncture , magnetic stimulation , mirabegron , posterior tibial nerve stimulation , sacral neuromodulation , and transvaginal electrical stimulation , are efficacious in the treatment of overactive bladder
The purpose of the study was to determine the efficacy and safety of nonantimuscarinic treatments for overactive bladder .