Results : Duloxetine may be an effective treatment for mood spectrum disorders , panic disorder , several symptom clusters of borderline personality , and as add-on drug in schizophrenia .
Modest or conflicting results have been found for the efficacy of duloxetine in obsessive-compulsive disorder , posttraumatic stress disorder , eating , and sexual disorders .
Background : Duloxetine hydrochloride ( DUL ) is an antidepressant included in the pharmacological class of serotonin-norepinephrine reuptake inhibitors approved for the treatment of major depressive disorder , generalized anxiety disorder , diabetic peripheral neuropathic pain , fibromyalgia , and chronic musculoskeletal pain .
The aim of this review was to eluci date current evidence s on the use of DUL in the treatment of a variety of psychiatric disorders .
Comparative study of the effects of venlafaxine and duloxetine on chemotherapy-induced peripheral neuropathy
Objective One of the complications of chemotherapy is peripheral neuropathy . Various studies have shown that potent norepinephrine and serotonin reuptake inhibitors such as gabapentin , venlafaxine and duloxetine have therapeutic effects on neuropathy . The aim of this study was to compare the effects of venlafaxine vs. duloxetine on chemotherapy-induced peripheral neuropathy . Methods In this clinical trial , cancer patients who were suffering from chemotherapy-induced peripheral neuropathy comprised the study population . They were r and omly assigned to three pharmacotherapy groups including venlafaxine , duloxetine and placebo . Cranial , sensory , motor neuropathies as well as neuropathic pain were evaluated on day 1 , week 2 , and week 4 after enrollment . Results Grade of cranial , motor , sensory and neuropathic pain decreased significantly in venlafaxine and duloxetine groups . This reduction was more considerable in duloxetine group compared to venlafaxine group ( P < 0.05 ) . Conclusion Duloxetine seems to be more effective than venlafaxine in decreasing the symptoms of chemotherapy-induced peripheral neuropathy .  Duloxetine was more effective than venlafaxine in decreasing motor neuropathy and neuropathic pain grade
Results : Duloxetine may be an effective treatment for mood spectrum disorders , panic disorder , several symptom clusters of borderline personality , and as add-on drug in schizophrenia .
Modest or conflicting results have been found for the efficacy of duloxetine in obsessive-compulsive disorder , posttraumatic stress disorder , eating , and sexual disorders .
Background : Duloxetine hydrochloride ( DUL ) is an antidepressant included in the pharmacological class of serotonin-norepinephrine reuptake inhibitors approved for the treatment of major depressive disorder , generalized anxiety disorder , diabetic peripheral neuropathic pain , fibromyalgia , and chronic musculoskeletal pain .
The aim of this review was to eluci date current evidence s on the use of DUL in the treatment of a variety of psychiatric disorders .