No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .
Structured medium and long chain triglycerides show short-term increases in fat oxidation, but no changes in adiposity in men.
BACKGROUND Medium chain triglycerides ( MCT ) have been suggested as modulators of human energy expenditure ( EE ) and thus may influence total and regional body fat distribution . OBJECTIVE To investigate in overweight men the effects of structured medium and long chain triglycerides on EE , substrate oxidation and body adiposity , compared to extra virgin olive oil ( OO ) . METHODS In a 6 week single-blind crossover study , 23 overweight men were r and omly assigned to consume a st and ard high-fat diet of which 75 % total fat was provided as either structured medium and long chain triglycerides referred to as structured oil ( StO ) , or OO .  EE and body composition were measured using indirect calorimetry and magnetic resonance imaging , respectively , at weeks 1 and 6 of each phase . RESULTS Body weight decreased ( p<0.01 ) from baseline to end-point during consumption of both the StO ( -1.46+/-0.4k g ) and OO ( -1.17+/-0.4 kg ) ; however , no significant treatment differences were observed . There were no changes in body composition among treatment groups . No differences between diets for EE measurements were reported . Fat oxidation rates did not differ between oils , but were reduced ( p<0.05 ) in the StO group between baseline ( 0.0020+/-0.0003 g/kg fat free mass per min ) in comparison to after week 6 ( 0.0013+/-0.0001 g/kg fat free mass per min ) . No differences in carbohydrate oxidation rate were noted across diets or time . CONCLUSION The present structured medium and long chain triglyceride oil increases short-term fat oxidation but fails to modulate body weight or adiposity through a change in EE
No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .