No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .
Phytosterols mixed with medium-chain triglycerides and high-oleic canola oil decrease plasma lipids in overweight men.
Phytosterols ( PSs ) have been recently added to various mediums . Nevertheless , matrices with functional properties , such as medium-chain triglycerides ( MCTs ) , should be precisely examined for supplementary advantages . The objective of this study was to identify the existence of combined biological actions of a functional oil enriched in PSs within MCTs and high-oleic canola ( HOC ) , relative to a control ( olive oil ) , in overweight , hyperlipidemic men using a rigorously controlled dietary intervention . Twenty-three overweight , hyperlipidemic men consumed both types of oil in a r and omized , crossover trial for 6 weeks each . Fasted plasma sample s were collected on the first and last 2 days of each study period . Body weight decreased -1.22 + /- 0.35 kg ( P = .0019 ) and -1.68 + /- 0.47 kg ( P = .0016 ) after the 6-week study period in the olive oil and functional oil groups , respectively . The end points for total cholesterol and low-density lipoprotein cholesterol ( LDL-C ) in the functional oil group ( P = .0006 ) were lower than in the olive oil group ( P = .0002 ) . Total cholesterol values decreased from comparable baseline to end point of 4.71 + /- 0.16 mmol/L ( P < .0001 ) in the functional oil phase and 5.14 + /- 0.19 mmol/L ( P = .0001 ) in the olive oil phase ( P = .0592 ) . In addition , LDL-C demonstrated a similar drop , to an end point of 3.12 + /- 0.16 mmol/L ( P < .0001 ) and 3.54 + /- 0.18 mmol/L ( P = .0002 ) , for the functional oil and olive oil groups , respectively , with significant changes ( P = .0221 ) . High-density lipoprotein cholesterol levels did not change in either treatment . Triacylglycerol end points decreased in functional oil and olive oil groups ( P = .0195 and .0105 , respectively ) to the same extent from baseline . Results indicate that PSs mixed within an MCT- and HOC-rich matrix lower plasma LDL-C , without significantly changing the high-density lipoprotein cholesterol concentrations , in hyperlipidemic , overweight men , and may therefore decrease the risk of cardiovascular events
No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .