Our case study successfully enabled us to address the four feasibility metrics , and we provide new information on management feasibility ( i.e. estimate data completeness and estimate data entry ) and scientific outcomes feasibility ( i.e. determining data collection material s appropriateness ) .
Conclusion Our review highlights the existing research and provides a case study which assesses important metrics of study feasibility .
Background Much research has been undertaken to establish the important benefits of physical activity in persons with multiple sclerosis ( MS ) .
There is disagreement regarding the strength of this research , perhaps because the majority of studies on physical activity and its benefits have not undergone initial and systematic feasibility testing .
We aim to address the feasibility processes that have been examined within the context of physical activity interventions in MS .
Cost effectiveness of a pragmatic exercise intervention (EXIMS) for people with multiple sclerosis: economic evaluation of a randomised controlled trial
Background : Exercise is a safe , non-pharmacological adjunctive treatment for people with multiple sclerosis but cost-effective approaches to implementing exercise within health care setting s are needed . Objective : The objective of this paper is to assess the cost effectiveness of a pragmatic exercise intervention in conjunction with usual care compared to usual care only in people with mild to moderate multiple sclerosis . Methods : A cost-utility analysis of a pragmatic r and omised controlled trial over nine months of follow-up was conducted . A total of 120 people with multiple sclerosis were r and omised ( 1:1 ) to the intervention or usual care . Exercising participants received 18 supervised and 18 home exercise sessions over 12 weeks . The primary outcome for the cost utility analysis was the incremental cost per quality -adjusted life year ( QALY ) gained , calculated using utilities measured by the EQ-5D question naire . Results : The incremental cost per QALY of the intervention was £ 10,137 per QALY gained compared to usual care . The probability of being cost effective at a £ 20,000 per QALY threshold was 0.75 , rising to 0.78 at a £ 30,000 per QALY threshold . Conclusion : The pragmatic exercise intervention is highly likely to be cost effective at current established thresholds , and there is scope for it to be tailored to particular sub-groups of patients or services to reduce its cost impact
Our case study successfully enabled us to address the four feasibility metrics , and we provide new information on management feasibility ( i.e. estimate data completeness and estimate data entry ) and scientific outcomes feasibility ( i.e. determining data collection material s appropriateness ) .
Conclusion Our review highlights the existing research and provides a case study which assesses important metrics of study feasibility .
Background Much research has been undertaken to establish the important benefits of physical activity in persons with multiple sclerosis ( MS ) .
There is disagreement regarding the strength of this research , perhaps because the majority of studies on physical activity and its benefits have not undergone initial and systematic feasibility testing .
We aim to address the feasibility processes that have been examined within the context of physical activity interventions in MS .