A systematic evaluation of the available evidence suggests similarities as well as important differences in the risk factors for incidence of AF as compared with other cardiovascular diseases , which has implication s for the primary prevention strategies for atrial fibrillation
Established primary prevention strategies of cardiovascular diseases are based on underst and ing of risk factors , but whether the same risk factors are associated with  atrial fibrillation ( AF )  remains unclear .
Fibrinogen and albumin levels and risk of atrial fibrillation in men and women (the Copenhagen City Heart Study).
Cross-sectional and limited prospect i ve evidence has suggested that inflammatory markers may predict for the risk of  atrial fibrillation ( AF ) .  In a prospect i ve cohort study , we studied the risk of incident AF among 8,870 women and men free of cardiovascular disease enrolled in the Copenhagen City Heart Study . We measured plasma fibrinogen and serum albumin levels  at a study visit from 1991 to 1994 . We identified 286 subsequent cases of AF during a mean of 7.5 years of follow-up by a vali date d nationwide registry of all hospitalizations . The fibrinogen levels at baseline were associated with a higher risk of AF , with a multivariate-adjusted hazard ratio for the highest versus lowest quartiles of 1.98 ( 95 % confidence interval [ CI ] 0.94 to 4.17 ) among men and 2.14 ( 95 % CI 1.15 to 3.96 ) among women . The albumin levels were inversely associated with the risk of AF among women ( hazard ratio 0.47 , 95 % CI 0.28 to 0.77 ) but not among men ( hazard ratio 1.01 , 95 % CI 0.56 to 1.84 ) . Additional adjustment for cases of coronary heart disease , congestive heart failure , and stroke that occurred during follow-up did not attenuate these associations . In conclusion , higher levels of fibrinogen and lower levels of albumin were prospect ively associated with a higher risk of AF , even accounting for their relation with the risk of cardiovascular disease . These findings support the hypothesis that inflammation contributes to the etiology of AF
A systematic evaluation of the available evidence suggests similarities as well as important differences in the risk factors for incidence of AF as compared with other cardiovascular diseases , which has implication s for the primary prevention strategies for atrial fibrillation
Established primary prevention strategies of cardiovascular diseases are based on underst and ing of risk factors , but whether the same risk factors are associated with  atrial fibrillation ( AF )  remains unclear .