Bariatric surgery leads to marked and long-lasting weight reduction .
A large proportion of patients undergoing bariatric surgery have DM2 .
Glycemic control improves in the months after laparoscopic adjustable gastric b and ing , but it improves more rapidly and completely after laparoscopic Roux-en-Y gastric bypass surgery .
Thus , both types of surgery are capable of improving or even curing DM2 , but the mechanisms may differ
OBJECTIVE To systematic ally review the literature pertaining to the reversal of  type 2 diabetes mellitus ( DM2 ) after Roux-en-Y gastric bypass and adjustable gastric b and ing .
Sleeve Gastrectomy and Gastric Banding: Effects on Plasma Ghrelin Levels
Background : Different changes of plasma ghrelin levels have been reported following gastric b and ing , Roux-en-Y gastric bypass , and biliopancreatic diversion . Methods : This prospect i ve study compares plasma ghrelin levels and weight loss following  laparoscopic sleeve gastrectomy ( LSG ) and laparoscopic adjustable gastric b and ing ( LAGB ) in 20 patients . Results : Patients who underwent LSG ( n=10 ) showed a significant decrease of plasma ghrelin at day 1 compared to preoperative values ( 35.8 ± 12.3 fmol/ml vs 109.6 ± 32.6 fmol/ml , P=0.005 ) . Plasma ghrelin remained low and stable at 1 and 6 months postoperatively . In contrast , no change of plasma ghrelin at day 1 ( 71.8 ± 35.3 fmol/ml vs 73.7 ± 24.8 fmol/ml , P=0.441 ) was found in patients after LAGB ( n=10 )  . Increased plasma ghrelin levels compared with the preoperative levels at 1 ( 101.9 ± 30.3 fmol/ml vs 73.7 ± 24.8 fmol/ml , P=0.028 ) and 6 months ( 104.9 ± 51.1 fmol/ml vs 73.7 ± 24.8 fmol/ml , P=0.012 ) after surgery were observed . Mean excess weight loss was higher in the LSG group at 1 ( 30 ± 13 % vs 17 ± 7 % , P=0.005 ) and 6 months ( 61 ± 16 % vs 29 ± 11 % , P=0.001 ) compared with the LAGB group . Conclusions : As a consequence of resection of the gastric fundus , the predominant area of human ghrelin production , ghrelin is significantly reduced after LSG but not after LAGB . This reduction remains stable at follow-up 6 months postoperatively , which may contribute to the superior weight loss when compared with LAGB
Bariatric surgery leads to marked and long-lasting weight reduction .
A large proportion of patients undergoing bariatric surgery have DM2 .
Glycemic control improves in the months after laparoscopic adjustable gastric b and ing , but it improves more rapidly and completely after laparoscopic Roux-en-Y gastric bypass surgery .
Thus , both types of surgery are capable of improving or even curing DM2 , but the mechanisms may differ
OBJECTIVE To systematic ally review the literature pertaining to the reversal of  type 2 diabetes mellitus ( DM2 ) after Roux-en-Y gastric bypass and adjustable gastric b and ing .