Results Insulin resistance indicators were significantly improved after bariatric surgery .
Leptin was also significantly decreased while adiponectin was significantly increased .
Although the level of metabolic hormones changed after bariatric surgery , they were not statistically significant .
Inflammation indicators were significantly decreased .
Significant reduction was also detected in PAI-1 and sICAM-1 .
Conclusions Bariatric surgery is beneficial in morbidly obese patients .
Although treating obesity in a surgical way may cause some complications , the weight loss is generally safe and effective
Background Considering conflicting results on the consequences of all types of obesity surgery , we were to summarize them via a systematic review .
A Prospective Study on Inflammatory Parameters in Obese Patients After Sleeve Gastrectomy
Different hormones and peptides involved in inflammation have been studied in and related to obesity . The aim of our work is to assess the variations of different molecules related to inflammation in obese patients during the first year following sleeve gastrectomy .  This was a prospect i ve study on patients who underwent sleeve gastrectomy .  The variations in different clinical , anthropometric , and analytical parameters related to inflammation were determined and analysed in all patients at the preoperative visit and at the first and fifth days , first and sixth months , and 1 year following surgery . We enrolled 20 patients to the study . The median body mass index ( BMI ) before intervention was 48.5 kg/m2 . With respect to comorbidities , 70 % of the patients had obstructive sleep apnoea syndrome ( OSA ) , 65 % high blood pressure , 45 % dyslipidaemia , and 40 % diabetes mellitus ( DM ) . The median percentage of BMI lost ( % BMI L ) 1 year after the intervention was 71 % . The dyslipidaemia healing or improvement rate was 100 % , whereas it was 87.5 % for diabetes , 84.6 % for hypertension , and 57.1 % for OSA . During the 1-year postintervention period , the average levels of adiponectin increased , although not significantly , whereas those of leptin significantly decreased . In addition , the blood levels of MCP-1 , IL-6 , CRP , ferritin , and PAI-1 significantly decreased in that period . Sleeve gastrectomy is a surgical technique that is associated with improvements in body weight and comorbid conditions from the first postoperative months , which lead to significant variations in the levels of different inflammation-related parameters and a decrease in the levels of leptin , IL-6 , CRP , MCP-1 , ferritin , and serpin ( PAI-1 )
Results Insulin resistance indicators were significantly improved after bariatric surgery .
Leptin was also significantly decreased while adiponectin was significantly increased .
Although the level of metabolic hormones changed after bariatric surgery , they were not statistically significant .
Inflammation indicators were significantly decreased .
Significant reduction was also detected in PAI-1 and sICAM-1 .
Conclusions Bariatric surgery is beneficial in morbidly obese patients .
Although treating obesity in a surgical way may cause some complications , the weight loss is generally safe and effective
Background Considering conflicting results on the consequences of all types of obesity surgery , we were to summarize them via a systematic review .