REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .
Evaluation of calcium-antagonist (Nifedipine) in the treatment of pre-eclampsia.
The therapeutic effect of the calcium antagonist ; Nifedipine was assessed in 30 patients with pre-eclampsia . Cases were r and omly allocated into two groups ; a study group ( n = 20 ) who received Nifedipine capsules ( 20 mg every 8 h for 7 days ) and a control group ( n = 10 ) who received placebo capsules with the same regimen . After Nifedipine administration , there was a significant decrease in blood pressure , serum urea and creatinine and 24 h urinary proteins . No significant difference was found in FHR and S/D ratio of the umbilical artery between study and control groups or between initial values and after Nifedipine administration . Preliminary results indicated that Nifedipine decreased blood pressure and improved kidney functions without affecting the umbilical artery blood flow in cases of pre-eclampsia
REVIEW ER 'S CONCLUSIONS It remains unclear whether antihypertensive drug therapy for mild-moderate hypertension during pregnancy is worthwhile
BACKGROUND Mild-moderate hypertension during pregnancy is common .
Antihypertensive drugs are often used in the belief that lowering blood pressure will prevent progression to more severe disease , and thereby improve outcome .
OBJECTIVES To assess the effects of antihypertensive drug treatments for women with mild to moderate hypertension during pregnancy .