The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .
Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial.
Non-alcoholic fatty liver disease ( NAFLD ) is a global health problem . Although many aspects of NAFLD pathogenesis have been understood , there is a paucity of effective treatments to be used as the second line when lifestyle modification is insufficient . Curcumin , a natural polyphenol from turmeric , has been shown to be effective against development of hepatic steatosis and its progression to steatohepatitis , yet these beneficial effects have not been explored in clinical practice . The aim of this study is to investigate the effects of curcumin on hepatic fat content as well as biochemical and anthropometric features of patients with NAFLD . In this r and omized double-blind placebo-controlled trial , patients with ultrasonographic evidence of NAFLD were r and omly assigned to receive an amorphous dispersion curcumin formulation ( 500 mg/day equivalent to 70-mg curcumin ) or matched placebo for a period of 8 weeks . Liver fat content ( assessed through ultrasonography ) , glycemic and lipid profile , transaminase levels , and anthropometric indices were evaluated at baseline and at the end of follow-up period . The clinical trial protocol was registered under the Iranian Registry of Clinical Trials ID : I RCT 2014110511763N18 . Compared with placebo , curcumin was associated with a significant reduction in liver fat content ( 78.9 % improvement in the curcumin vs 27.5 % improvement in the placebo group ) . There were also significant reductions in body mass index and serum levels of total cholesterol , low-density lipoprotein cholesterol , triglycerides , aspartate aminotransferase , alanine aminotransferase , glucose , and glycated hemoglobin compared with the placebo group . Curcumin was safe and well tolerated during the course of trial . Findings of the present proof-of-concept trial suggested improvement of different features of NAFLD after a short-term supplementation with curcumin . Copyright © 2016 John Wiley & Sons ,
The effects of curcuminoids on lipids were not found to be dependent on the duration of supplementation .
Conclusion : This meta- analysis has shown that curcuminoid therapy significantly reduces plasma triglycerides and increases HDL-C levels
ABSTRACT Objective : The aim of this systematic review and meta- analysis was to determine and clarify the impact of curcuminoids on  serum lipid levels .