No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .
Effect of dietary medium- and long-chain triacylglycerols (MLCT) on accumulation of body fat in healthy humans.
We investigated whether a structured medium- and long-chain triacylglycerols ( MLCT ) diet could decrease accumulation of body fat in healthy humans . The study was conducted under a double-blind r and omized design . Ninety-three subjects participated in this study . However , 10 subjects could not consume the specified meal , and one subject wished to opt out . Consequently , the study included 82 subjects . The experimental subjects consumed the test bread , which was made with 14 g of MLCT containing 1.7 g MCFA , daily at breakfast during the study period of 12 weeks , and the control subjects consumed bread made with long-chain triacylglycerols ( LCT ) . All subjects consumed the same st and ard packaged meals .  Body composition parameters were body weight , total body fat and abdominal fat , and blood analyses included serum cholesterol , triacylglycerols and phospholipids . Significant decreases of body weight , the amount of body fat , subcutaneous and visceral fat were noted in the MLCT group as compared with those of the LCT group for 12 weeks ( P<0.05 ) . Furthermore , a significant decrease in serum total cholesterol was noted in the MLCT group as compared with that of the LCT group at 8 weeks ( P<0.05 ) . However , other serum parameters were not different between the MLCT and LCT groups . The results suggest that the daily intake of MLCT diet could result in a reduction in body weight and in accumulation of body fat , and , moreover , it could reduce serum total cholesterol
No differences were seen in blood lipid levels .
Replacement of LCTs with MCTs in the diet could potentially induce modest reductions in body weight and composition without adversely affecting lipid profiles .
BACKGROUND Medium-chain triglycerides ( MCTs ) may result in negative energy balance and weight loss through increased energy expenditure and lipid oxidation .
However , results from human intervention studies investigating the weight reducing potential of MCTs , have been mixed .
OBJECTIVE To conduct a systematic review and meta- analysis of r and omized controlled trials comparing the effects of MCTs , specifically C8:0 and C10:0 , to long-chain triglycerides ( LCTs )  on weight loss and body composition in adults .