Several studies of good quality demonstrated changes in lifestyle habits arising from the provision of genetic interventions .
The most promising lifestyle changes were changes in nutrition .
Conclusions : It is possible to facilitate behaviour change using genetic testing as the catalyst .
Background : Study ing the impact of  genetic testing interventions on lifestyle behaviour change  has been a priority area of research in recent years .
Substantial heterogeneity exists in the results and conclusions of this literature , which has yet to be explained using vali date d behaviour change theory and an assessment of the quality of genetic interventions .
The theory of planned behaviour ( TPB ) helps to explain key contributors to behaviour change .
It has been hypothesized that personalization could be added to this theory to help predict changes in health behaviours .
Purpose : This systematic review provides a detailed , comprehensive identification , assessment , and summary of primary research articles pertaining to  lifestyle behaviour change  ( nutrition , physical activity , sleep , and smoking ) result ing from  genetic testing interventions .
The present review further aims to provide in-depth analyses of studies conducted to date within the context of the TPB and the quality of genetic interventions provided to participants while aim ing to determine whether or not genetic testing facilitates changes in lifestyle habits .
This review is timely in light of a recently published “ call-to-action ” paper , highlighting the need to incorporate the TPB into personalized healthcare behaviour change research .
Genetic susceptibility testing in smoking-cessation treatment: one-year outcomes of a randomized trial.
This study evaluated the long-term impact of genetic susceptibility biomarker feedback on smoking behavior change and symptoms of depression in 426 male and female smokers . Smokers were r and omized to one of three smoking-cessation interventions : minimal contact quit-smoking counseling ( QSC ) , QSC + exposure biomarker feedback ( EBF ) , and QSC + EBF + biomarker feedback about genetic susceptibility to lung cancer ( SBF ) . The logistic regression model for quit attempt revealed a significant main effect for treatment such that participants in the SBF group were more than two times more likely to make a quit attempt than participants in the QSC group . There was not a significant difference between EBF and QSC participants . The results also revealed a significant effect for baseline stage of change . Those smokers in the preparation stage at baseline were more than three times more likely to make a quit attempt over the 12 months following treatment . The models for 30-day cessation and follow-up smoking rate revealed no significant main or interacting effects for treatment . A repeated measures analysis of variance revealed a significant main effect for time , indicating that an initial increase in depression in the genetic susceptibility group was not maintained over time . Genetic susceptibility feedback has the intended effects on motivation to quit , but it may need to be delivered within a more intensive smoking-cessation treatment for the heightened motivation to translate into smoking cessation
Several studies of good quality demonstrated changes in lifestyle habits arising from the provision of genetic interventions .
The most promising lifestyle changes were changes in nutrition .
Conclusions : It is possible to facilitate behaviour change using genetic testing as the catalyst .
Background : Study ing the impact of  genetic testing interventions on lifestyle behaviour change  has been a priority area of research in recent years .
Substantial heterogeneity exists in the results and conclusions of this literature , which has yet to be explained using vali date d behaviour change theory and an assessment of the quality of genetic interventions .
The theory of planned behaviour ( TPB ) helps to explain key contributors to behaviour change .
It has been hypothesized that personalization could be added to this theory to help predict changes in health behaviours .
Purpose : This systematic review provides a detailed , comprehensive identification , assessment , and summary of primary research articles pertaining to  lifestyle behaviour change  ( nutrition , physical activity , sleep , and smoking ) result ing from  genetic testing interventions .
The present review further aims to provide in-depth analyses of studies conducted to date within the context of the TPB and the quality of genetic interventions provided to participants while aim ing to determine whether or not genetic testing facilitates changes in lifestyle habits .
This review is timely in light of a recently published “ call-to-action ” paper , highlighting the need to incorporate the TPB into personalized healthcare behaviour change research .