There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .
Enhanced Nutrient Supply to Very Low Birth Weight Infants is Associated with Improved White Matter Maturation and Head Growth
Background : Extrauterine growth restriction is common among very low birth weight infants ( VLBW , BW < 1,500 g ) . Optimal postnatal nutrient supply is essential to limit growth restriction and ensure adequate growth and neurodevelopment . Objectives : We compared an enhanced postnatal nutrient supply to a st and ard supply and evaluated the effects on growth velocity , head circumference growth and cerebral maturation - the latter by magnetic resonance diffusion tensor imaging ( DTI ) . We hypothesized increased growth velocity , head circumference growth and decreased mean diffusivity ( MD ) in cerebral white matter ( WM ) areas , suggesting improved cerebral maturation among infants on the enhanced nutrient supply . Methods : In this r and omized controlled trial , infants on the enhanced nutrient supply received increased amounts of energy , protein , fat , essential fatty acids and vitamin A until discharge . DTI was performed close to term equivalent age . Outcomes were growth velocity , head circumference growth and WM mean diffusivity . Results : Among the 50 included infants , 14 in the intervention group and 11 controls underwent a successful DTI . Infants on the enhanced diet achieved improved growth velocity ( 16.5 vs. 13.8 g/kg/day , p = 0.01 ) and increased head circumference ( Δz score : 0.24 vs. -0.12 , p = 0.15 ) . A significantly lower MD was seen in a large WM area such as the superior longitudinal fasciculi ( 1.19 × 10 - 3 vs. 1.24 × 10 - 3 mm2/s , p = 0.04 , adjusted for age when scanned ) . Conclusions : Enhanced nutrient supply to VLBW infants is associated with improved growth velocity , increased head circumference growth and decreased regional WM mean diffusivity , suggesting improved maturation of cerebral connective tracts
There is no evidence that PUFA supplementation in infancy has an effect on infant or childhood allergy , asthma , dermatitis/eczema or food allergy .
However , the quality of evidence was very low .
There was insufficient evidence to determine an effect on allergic rhinitis
BACKGROUND Early dietary intakes may influence the development of allergic disease .
It is important to determine if dietary polyunsaturated fatty acids ( PUFAs ) given as supplements or added to infant formula prevent the development of allergy .
OBJECTIVES To determine the effect of higher PUFA intake during infancy to prevent allergic disease .