The review found that multifaceted interventions , addressing several non-adherence factors , were comparatively more effective in improving medication adherence and glycaemic target in patients with T2D than single strategies .
However , interventions with similar components and those addressing similar non-adherence factors demonstrated mixed results , making it difficult to conclude on effective intervention strategies to promote adherence .
Educational strategies have remained the most popular intervention strategy , followed by behavioural , with affective components becoming more common in recent years .
There is a noticeable shift in the literature from using single to multifaceted intervention strategies addressing a range of factors impacting adherence to medications .
BACKGROUND Poor adherence to anti-diabetic medications contributes to suboptimal glycaemic control in patients with type 2 diabetes ( T2D ) .
A range of interventions have been developed to promote anti-diabetic medication adherence .
However , there has been very little focus on the characteristics of these interventions and how effectively they address factors that predict non-adherence .
In this systematic review we assessed the characteristics of interventions that aim ed to promote adherence to anti-diabetic medications .
Improving Adherence and Reducing Medication Discrepancies in Patients with Diabetes
OBJECTIVE : To improve medication adherence by reducing self-reported adherence barriers , and to identify medication discrepancies by comparing physician-prescribed and patient-reported medical regimens . DESIGN : Prospect i ve , r and omized , controlled trial . SETTING AND PARTICIPANTS : A single academically affiliated community health center . Eligible patients had type 2 diabetes , had undergone laboratory testing in the year preceding the study , and had visited the clinic in the 6 months preceding the study . INTERVENTION : A pharmacist administered detailed question naires , provided tailored education regarding medication use and help with appointment referrals , and created a summary of adherence barriers and medication discrepancies that was entered into the medical record and electronically forwarded to the primary care provider . MEASUREMENTS : Changes in self-reported adherence rates and barriers were compared 3 months after the initial interview . Intervention patients with medication discrepancies at baseline were assessed for resolution of discrepancies at 3 months . RESULTS : Rates of self-reported medication adherence were very high and did not improve further at 3 months ( 6.9 of 7 d , with all medicines taken as prescribed ; p = 0.3 ) . Medical regimen discrepancies were identified in 44 % of intervention patients , involving 45 doses of medicines . At 3-month follow-up , 60 % of discrepancies were resolved by corrections in the medical record , while only 7 % reflected corrections by patients . CONCLUSIONS : In this community cohort , patients reported few adherence barriers and very high medication adherence rates . Our patient-tailored intervention did not further reduce these barriers or improve self-reported adherence . The high prevalence of medication discrepancies appeared to mostly reflect inaccuracies in the medical record rather than patient errors
The review found that multifaceted interventions , addressing several non-adherence factors , were comparatively more effective in improving medication adherence and glycaemic target in patients with T2D than single strategies .
However , interventions with similar components and those addressing similar non-adherence factors demonstrated mixed results , making it difficult to conclude on effective intervention strategies to promote adherence .
Educational strategies have remained the most popular intervention strategy , followed by behavioural , with affective components becoming more common in recent years .
There is a noticeable shift in the literature from using single to multifaceted intervention strategies addressing a range of factors impacting adherence to medications .
BACKGROUND Poor adherence to anti-diabetic medications contributes to suboptimal glycaemic control in patients with type 2 diabetes ( T2D ) .
A range of interventions have been developed to promote anti-diabetic medication adherence .
However , there has been very little focus on the characteristics of these interventions and how effectively they address factors that predict non-adherence .
In this systematic review we assessed the characteristics of interventions that aim ed to promote adherence to anti-diabetic medications .