There were no significant effects of organisational  interventions on lipid profile , HbA1c , medication adherence or recurrent cardiovascular events .
Pooled results indicated that educational interventions were not associated with clear differences in any of the review outcomes .
The estimated effects of organisational interventions were compatible with improvements and no differences in several modifiable risk factors .
BACKGROUND People with stroke or transient ischaemic attack ( TIA ) are at increased risk of future stroke and other cardiovascular events .
Evidence -based strategies for secondary stroke prevention have been established .
However , the implementation of prevention strategies could be improved .
OBJECTIVES To assess the effects of stroke service interventions for implementing secondary stroke prevention strategies on modifiable risk factor control , including patient adherence to prescribed medications , and the occurrence of secondary cardiovascular events .
Modified informed consent procedure: consent to postponed information
How do you obtain a valid assessment of subjective outcomes in a trial in which the participants can not be blinded to the intervention ? Bias is inevitable from unblinded patients , but trials that have not told patients about treatment in all arms have been heavily criticised . Asking participants to consent to postponed information could be a solution The most powerful tool for study ing the effectiveness of a medical treatment is a r and omised controlled clinical trial with blinded assessment of outcomes . However , blinding is not always possible — for example , in a trial comparing a surgical intervention with non-surgical treatment or the effectiveness of supplemental care compared with conventional care . Blinding needs special attention in such studies in order to prevent bias . When outcomes are assessed by doctors , it is often easy for the assessment to be done by doctors other than those who performed the procedure . However , when studies measure patients ' assessment of outcomes , blinding is much more complicated or even impossible . ! [ ] [ 1 ] Credit : PETER GRAY Unblinded patients who assess outcomes after being informed about the different treatment options during recruitment might bias the results of a study . The likelihood of bias increases when patients have a preference for one of the treatment options . For example , patients may have been told during recruitment that the new or supplemental strategy has been developed because the current strategy has disadvantages . The best way to obtain valid assessment s in such studies remains unclear . Intense debate was generated when research ers tried to mask patients … [ 1 ] :
There were no significant effects of organisational  interventions on lipid profile , HbA1c , medication adherence or recurrent cardiovascular events .
Pooled results indicated that educational interventions were not associated with clear differences in any of the review outcomes .
The estimated effects of organisational interventions were compatible with improvements and no differences in several modifiable risk factors .
BACKGROUND People with stroke or transient ischaemic attack ( TIA ) are at increased risk of future stroke and other cardiovascular events .
Evidence -based strategies for secondary stroke prevention have been established .
However , the implementation of prevention strategies could be improved .
OBJECTIVES To assess the effects of stroke service interventions for implementing secondary stroke prevention strategies on modifiable risk factor control , including patient adherence to prescribed medications , and the occurrence of secondary cardiovascular events .