HRM  treatment is associated with clinical improvement in diseases of the skin , respiratory , circulatory , digestive and nervous system among others .
The scientific literature of the last decade has shown that a number of non-musculoskeletal disorders are treated with different kinds of  HRM .
Health resort medicine ( HRM ; in German : Kurortmedizin ) is a field of medicine with long-lasting tradition in several European countries .
A number of systematic review s have shown the effectiveness of HRM  in musculoskeletal conditions .
Review s focusing on the effectiveness of HRM in non-musculoskeletal disorders are rare .
This systematic review aims to provide an overview about all types of health resort treatments applied in non-musculoskeletal conditions , to summarize evidence for its effectiveness and to assess the quality of published studies .
Health resort treatment improved the neurosteroid profile in thyroidectomized women.
OBJECTIVE The aim was to study the effect of climatotherapy and spa treatment on selected neuro- and immunomodulatory steroids known to affect well-being , and homocysteine , in a homogenous group of thyroidectomized women under st and ard substitution regime . METHODS Dehydroepi and rosterone , its precursors and metabolites , cortisol , major sex steroids , SHBG , and homocysteine were measured before and after three-weeks stay in a health resort Jeseník ( Graefenberg ) in Czech Republic . The studied group consisted of 21 women after total thyroidectomy which was performed at least 3 months before the admission to the spa resort . All patients received thyroid hormone substitution treatment which was not changed during their stay in that resort . RESULTS Out of the steroids investigated , five , namely dehydroepi and rosterone , and rostenedione , testosterone , 7beta-hydroxy-dehydroepi and rosterone and cortisol were changed significantly after treatment . The most considerable was the decrease of cortisol and of homocysteine ( p < 0.000 each ) . CONCLUSION Spa resort treatment of thyroidectomized women substituted with thyroid hormones result ed in significant , mostly beneficial effects on steroid spectrum . This effect was achieved without any use of psychopharmacs
HRM  treatment is associated with clinical improvement in diseases of the skin , respiratory , circulatory , digestive and nervous system among others .
The scientific literature of the last decade has shown that a number of non-musculoskeletal disorders are treated with different kinds of  HRM .
Health resort medicine ( HRM ; in German : Kurortmedizin ) is a field of medicine with long-lasting tradition in several European countries .
A number of systematic review s have shown the effectiveness of HRM  in musculoskeletal conditions .
Review s focusing on the effectiveness of HRM in non-musculoskeletal disorders are rare .
This systematic review aims to provide an overview about all types of health resort treatments applied in non-musculoskeletal conditions , to summarize evidence for its effectiveness and to assess the quality of published studies .