Conclusions Exercise-based cardiac rehabilitation is effective at reducing important clinical outcomes in patients with coronary heart disease .
While our analysis was constrained by the quality of included trials and missing information about intervention components , there appears to be little differential effect of variations in exercise intervention , particularly on mortality outcomes .
Background While the clinical benefits of exercise-based cardiac rehabilitation are well established , there is extensive variation in the interventions used within these trials .
It is unknown whether variations in individual components of these exercise interventions provide different relative contributions to overall clinical outcomes .
This study aims to systematic ally examine the relationship between individual components of the exercise intervention in cardiac rehabilitation ( such as intensity and frequency ) and clinical outcomes for people with coronary heart disease .
Effects of exercise training on HbA1c and VO2peak in patients with type 2 diabetes and coronary artery disease: A randomised clinical trial
Objective : Few exercise trials have focused on patients with both type 2 diabetes and coronary artery disease . We investigated the effects of 1 year of exercise training on HbA1c and VO2peak in these patients . Methods : Patients with type 2 diabetes and coronary artery disease ( n = 137 ) were r and omised to combined exercise training or control group .  HbA1c was measured at the beginning and end of the study . Changes in VO2peak , and also ventilatory threshold and time to exhaustion , were assessed by cardiopulmonary exercise testing . Results : No differences in changes between the r and omised groups were observed in HbA1c and VO2peak , whereas ventilatory threshold and time to exhaustion increased significantly in the exercise group compared with the controls ( p = 0.046 and p = 0.034 ) . In patients without previous acute myocardial infa rct ion and diabetes microvascular complications ( n = 46 ) , the exercise group did improve HbA1c and VO2peak compared with the controls ( p = 0.052 and p = 0.035 ) . Conclusion : No significant effects of exercise training on HbA1c or VO2peak were observed in patients with type 2 diabetes and coronary artery disease , although improvements were seen in patients without vascular complications beyond coronary artery disease , implying that the degree of vascular disease may influence exercise responses . Ventilatory threshold and time to exhaustion did increase significantly , indicating improved exercise performance despite the minor change in VO2peak
Conclusions Exercise-based cardiac rehabilitation is effective at reducing important clinical outcomes in patients with coronary heart disease .
While our analysis was constrained by the quality of included trials and missing information about intervention components , there appears to be little differential effect of variations in exercise intervention , particularly on mortality outcomes .
Background While the clinical benefits of exercise-based cardiac rehabilitation are well established , there is extensive variation in the interventions used within these trials .
It is unknown whether variations in individual components of these exercise interventions provide different relative contributions to overall clinical outcomes .
This study aims to systematic ally examine the relationship between individual components of the exercise intervention in cardiac rehabilitation ( such as intensity and frequency ) and clinical outcomes for people with coronary heart disease .