Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .
High phosphorus intake only slightly affects serum minerals, urinary pyridinium crosslinks and renal function in young women
Objective : Assessment of the physiological effects of a diet rich in phosphorus in young women . Design : Control period I — commercial basic diet containing 1700 mg P and 1500 mg Ca/day for 4 weeks . Supplementation period — a 6 week high-phosphorus period of 3008 mg P and 1995 mg Ca/day . Control period II—4 weeks washout with basic diet as in period I. Setting : Institute of Nutritional Science , Friedrich Schiller University , Jena . Subjects : Ten healthy women , aged 20–30 y. Interventions : Orange juice and tablets , containing supplements of Ca5(PO4)3OH and NaH2PO4 , totalling 1436 mg elemental phosphorus per day . Results : There was an increase of 10.7±13.7 pg/ml in serum PTH , a decrease of 0.6±0.6 ng/ml in serum osteocalcin , an increase of 73.6±136.6 nmol/mmol creatinine in urinary pyridinoline and of 19.3±36.0 nmol/mmol creatinine in urinary deoxypyridinoline , and a decrease of 2.6±9.3 mg/l in urinary microalbumin . All changes were insignificant . There were no changes in serum levels of Ca , PO4 or Zn , in serum concentration of 1,25-(OH)2D3 , and in urinary β-2-microglobulin excretion  . Phosphorus supplementation  caused intestinal distress , soft stools or mild diarrhoea . Conclusions : In spite of a high phosphorus supplementation no significant changes in bone-related hormones , pyridinium crosslinks as markers of bone resorption and parameters of renal function in young women were found . European Journal of Clinical Nutrition ( 2001 ) 55 ,
Urine calcium excretion rates were consistent with osteoporosis development ; however calcium balance studies did not demonstrate loss of whole body calcium with higher net acid excretion .
No study revealed a biologic mechanism functioning at physiological pH. Finally , r and omized studies did not provide evidence for an adverse role of phosphate , milk , and grain foods in osteoporosis .
Conclusions A causal association between dietary acid load and osteoporotic bone disease is not supported by evidence and there is no evidence that an alkaline diet is protective of bone health
Background Modern diets have been suggested to increase systemic acid load and net acid excretion .
In response , alkaline diets and products are marketed to avoid or counteract this acid , help the body regulate its pH to prevent and cure disease .
The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill 's criteria .