Despite limitations in these data , our NMA findings are in line with existing evidence on the metabolic effects of fat and support current recommendations to replace high saturated-fat food with unsaturated oils
The aim of this network meta- analysis ( NMA ) is to compare the effects of different oils/solid fats on blood lipids .
The Type of Fat Ingested at Breakfast Influences the Plasma Lipid Profile of Postmenopausal Women
To assess whether the type of fat ingested at breakfast can modify the plasma lipid profile and other cardiovascular risk variables in postmenopausal women at risk of cardiovascular disease , a longitudinal , r and omized , and crossover study was carried out with postmenopausal women at risk of CVD . They were r and omly assigned to eat each type of breakfast during one month : 6 study periods ( breakfast with the same composition plus butter/margarine/virgin olive oil ) separated by two washout periods . On the first and last days of each study period , weight , arterial blood pressure , heart rate , and body mass index were recorded in fasting conditions and a blood sample was collected to measure plasma lipid profile . When comparing final values to baseline values , we only found out statistically significant differences on plasma lipid profiles .  Butter-based breakfast increased total cholesterol and HDL , while margarine-based breakfast decreased total cholesterol and LDL and increased HDL . After the olive oil-based breakfast intake , a tendency towards a decrease of total cholesterol and LDL levels and an increase of HDL levels was observed . No statistically significant differences were observed in triglycerides levels , BMI , and arterial pressure in any breakfast type . The margarine-based breakfast was the only one which significantly increased the percentage of volunteers with optimal lipid profiles . The polyunsaturated fat at breakfast has improved the plasma lipid profile in the analyzed sample population , suggesting that PUFA-based breakfast can be advisable in women at risk of CVD
Despite limitations in these data , our NMA findings are in line with existing evidence on the metabolic effects of fat and support current recommendations to replace high saturated-fat food with unsaturated oils
The aim of this network meta- analysis ( NMA ) is to compare the effects of different oils/solid fats on blood lipids .