HT treatment with estrogens alone or in combination with progestogens was associated with a small to moderate improvement in sexual function , particularly in pain , when used in women with menopausal symptoms or in early postmenopause ( within five years of amenorrhoea ) , but not in unselected postmenopausal women .
The current evidence does not suggest an important effect of tibolone or of SERMs alone or combined with estrogens on sexual function .
BACKGROUND The perimenopausal and postmenopausal periods are associated with many symptoms , including sexual complaints .
OBJECTIVES To assess the effect of hormone therapy ( HT ) on  sexual function in perimenopausal and postmenopausal women .
The Effect of Short‐Term Estrogen Replacement Therapy on Cognition: A Randomized, Double‐Blind, Cross‐Over Trial in Postmenopausal Women
Objective To evaluate the effect of estrogen replacement therapy on cognitive functioning . Methods The study consisted of two 3-month treatment periods , one with estrogen and one with the placebo , in r and om order , separated by a 1-month wash-out period . The study group comprised 70 healthy postmenopausal women , aged 47–65 years , with previous hysterectomy . Sixty-two women completed the study .  Cognitive speed and accuracy , attention , and memory were evaluated . Serum estradiol ( E2 ) and FSH levels were controlled at the end of the estrogen , placebo , and wash-out periods . Results Most of the cognitive tests correlated with age : older women were slower and made errors than younger women . Estrogen replacement therapy was not superior to the placebo in any test of cognitive performance . In two out of ten visual detection tasks , recognition thresholds were longer with estrogen than with the placebo ( P < .001 and P = .004 ) . On the most dem and ing test of working memory , the reaction times ( P = .045 ) and error rates ( P = .043 ) differed between treatments , yet this finding proved to be an effect of learning rather than treatment . There was no correlation between cognitive performance and serum E2 levels . Conclusion Cognitive performance decreased with age . Short-term estrogen replacement therapy did not provide any advantage over the placebo in terms of improving the performance
HT treatment with estrogens alone or in combination with progestogens was associated with a small to moderate improvement in sexual function , particularly in pain , when used in women with menopausal symptoms or in early postmenopause ( within five years of amenorrhoea ) , but not in unselected postmenopausal women .
The current evidence does not suggest an important effect of tibolone or of SERMs alone or combined with estrogens on sexual function .
BACKGROUND The perimenopausal and postmenopausal periods are associated with many symptoms , including sexual complaints .
OBJECTIVES To assess the effect of hormone therapy ( HT ) on  sexual function in perimenopausal and postmenopausal women .