Increased time in sedentary behaviour was significantly associated with higher levels of C Reactive Protein and LDL Cholesterol , and a larger newborn abdominal circumference .
Discrepancies were found in associations of sedentary behaviour with gestational weight gain , hypertensive disorders , and birth weight .
No consistent associations were found between sedentary behaviour and other variables such as gestational diabetes .
Conclusions Our review highlights the significant time spent in sedentary behaviour during pregnancy , and that sedentary behaviour may impact on pregnancy outcomes for both mother and child .
Background In the general population , at least 50 % of time awake is spent in sedentary behaviours .
Sedentary behaviours are activities that expend less energy than 1.5 metabolic equivalents , such as sitting .
The amount of time spent in sedentary behaviours is a risk factor for diseases such as type 2 diabetes , cardiovascular disease , and death from all causes .
Even individuals meeting physical activity guidelines are at a higher risk of premature death and adverse metabolic outcomes if they sit for extended intervals .
The associations between sedentary behaviour with type 2 diabetes and with impaired glucose tolerance are stronger for women than for men .
It is not known whether sedentary behaviour in pregnancy influences pregnancy outcomes , but if those negative outcomes observed in general adult population also occur in pregnancy , this could have implication s for adverse outcomes for mothers and offspring .
We aim ed to determine the proportion of time spent in sedentary behaviours among pregnant women , and the association of sedentary behaviour with pregnancy outcomes in mothers and offspring .
Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial.
BACKGROUND Behavioural interventions might improve clinical outcomes in pregnant women who are obese . We aim ed to investigate whether a complex intervention addressing diet and physical activity could reduce the incidence of gestational diabetes and large-for-gestational-age infants . METHODS The UK Pregnancies Better Eating and Activity Trial ( UPBEAT ) is a r and omised controlled trial done at antenatal clinics in eight hospitals in multi-ethnic , inner-city locations in the UK . We recruited pregnant women ( 15 - 18 weeks plus 6 days of gestation ) older than 16 years who were obese ( BMI ≥30 kg/m(2 ) ) . We r and omly assigned participants to either a behavioural intervention or st and ard antenatal care with an internet-based , computer-generated , r and omisation procedure , minimising by age , ethnic origin , centre , BMI , and parity . The intervention was delivered once a week through eight health trainer-led sessions . Primary outcomes were gestational diabetes ( diagnosed with an oral glucose tolerance test and by criteria from the International Association of Diabetes in Pregnancy Study Groups ) and large-for-gestational-age infants ( ≥90th customised birthweight centile ) . Analysis was by intention to treat . This trial is registered with Current Controlled Trials , ISCRTN89971375 . Recruitment and pregnancy outcomes are complete but childhood follow-up is ongoing . FINDINGS Between March 31 , 2009 , and June 2 , 2014 , we assessed 8820 women for eligibility and recruited 1555 , with a mean BMI of 36·3 kg/m(2 ) ( SD 4·8 ) . 772 were r and omly assigned to st and ard antenatal care and 783 were allocated the behavioural intervention , of which 651 and 629 women , respectively , completed an oral glucose tolerance test . Gestational diabetes was reported in 172 ( 26 % ) women in the st and ard care group compared with 160 ( 25 % ) in the intervention group ( risk ratio 0·96 , 95 % CI 0·79 - 1·16 ; p=0·68 ) . 61 ( 8 % ) of 751 babies in the st and ard care group were large for gestational age compared with 71 ( 9 % ) of 761 in the intervention group ( 1·15 , 0·83 - 1·59 ; p=0·40 ) . Thus , the primary outcomes did not differ between groups , despite improvements in some maternal secondary outcomes in the intervention group , including reduced dietary glycaemic load , gestational weight gain , and maternal sum-of-skinfold thicknesses , and increased physical activity . Adverse events included neonatal death ( two in the st and ard care group and three in the intervention group ) and fetal death in utero ( ten in the st and ard care group and six in the intervention group ) . No maternal deaths were reported . Incidence of miscarriage ( 2 % in the st and ard care group vs 2 % in the intervention group ) , major obstetric haemorrhage ( 1 % vs 3 % ) , and small-for-gestational-age infants ( ≤5th customised birthweight centile ; 6 % vs 5 % ) did not differ between groups . INTERPRETATION A behavioural intervention addressing diet and physical activity in women with obesity during pregnancy is not adequate to prevent gestational diabetes , or to reduce the incidence of large-for-gestational-age infants . FUNDING National Institute for Health Research , Guys and St Thomas ' Charity , Chief Scientist Office Scotl and , Tommy 's Charity
Increased time in sedentary behaviour was significantly associated with higher levels of C Reactive Protein and LDL Cholesterol , and a larger newborn abdominal circumference .
Discrepancies were found in associations of sedentary behaviour with gestational weight gain , hypertensive disorders , and birth weight .
No consistent associations were found between sedentary behaviour and other variables such as gestational diabetes .
Conclusions Our review highlights the significant time spent in sedentary behaviour during pregnancy , and that sedentary behaviour may impact on pregnancy outcomes for both mother and child .
Background In the general population , at least 50 % of time awake is spent in sedentary behaviours .
Sedentary behaviours are activities that expend less energy than 1.5 metabolic equivalents , such as sitting .
The amount of time spent in sedentary behaviours is a risk factor for diseases such as type 2 diabetes , cardiovascular disease , and death from all causes .
Even individuals meeting physical activity guidelines are at a higher risk of premature death and adverse metabolic outcomes if they sit for extended intervals .
The associations between sedentary behaviour with type 2 diabetes and with impaired glucose tolerance are stronger for women than for men .
It is not known whether sedentary behaviour in pregnancy influences pregnancy outcomes , but if those negative outcomes observed in general adult population also occur in pregnancy , this could have implication s for adverse outcomes for mothers and offspring .
We aim ed to determine the proportion of time spent in sedentary behaviours among pregnant women , and the association of sedentary behaviour with pregnancy outcomes in mothers and offspring .