The best evidence lies with probiotics supplementation in mothers and infants in preventing development and reducing severity of AD .
Specifically , Lactobacillus rhamnosus GG was effective in long-term prevention of AD development .
γ-Linolenic acid reduced severity of AD .
Supplementation with prebiotics and black currant seed oil ( γ-linolenic acid and ω-3 combination ) was effective in reducing the development of AD .
Certain types of nutrient supplementation are beneficial in preventing AD development and reducing its severity .
OBJECTIVE To identify whether nutrient supplementation with probiotics , prebiotics , formula , or fatty acids prevents the development of  atopic dermatitis ( AD ) or reduces the severity of AD in newborns to children younger than 3 years .
A randomized, single-blind and crossover study of an amino acid-based milk formula in treating young children with atopic dermatitis.
Cow 's milk and soy protein allergies are commonly associated with atopic dermatitis ( AD ) in young children .  Amino acid (AA)-based elemental milk formula may improve AD control in these patients . This study investigates the efficacy of AA-based formula in treating young AD patients irrespective of their food allergy status . AD patients younger than 3 yr old were eligible . Sensitization to food allergens was ascertained by skin prick tests and allergen-specific immunoglobulin E ( IgE ) assay . Patients were then r and omly allocated to take either active treatment or pre-existing formulae ( placebo ) for 6 wk . They were allowed a 6-wk washout period before crossed over to the other intervention for another 6 wk . Fifteen AD patients , with median ( interquartile range , IQR ) age of 1.4 ( 0.6 - 2.6 ) yr , were recruited . Their median ( IQR ) SCORAD score was 23.9 ( 10.5 - 29.7 ) . Seven of them were sensitized to cow 's milk or soybean . Among 11 patients who completed the study , the median changes for all scores and urinary eosinophil protein X ( EPX ) concentration were not statistically significant . There was also no evidence of carry-over effects for SCORAD and its various components and global health score , except for urinary EPX concentration ( p = 0.05 ) . Our results do not support the use of AA-based elemental milk formula in treating young children with AD irrespective of their food allergy status
The best evidence lies with probiotics supplementation in mothers and infants in preventing development and reducing severity of AD .
Specifically , Lactobacillus rhamnosus GG was effective in long-term prevention of AD development .
γ-Linolenic acid reduced severity of AD .
Supplementation with prebiotics and black currant seed oil ( γ-linolenic acid and ω-3 combination ) was effective in reducing the development of AD .
Certain types of nutrient supplementation are beneficial in preventing AD development and reducing its severity .
OBJECTIVE To identify whether nutrient supplementation with probiotics , prebiotics , formula , or fatty acids prevents the development of  atopic dermatitis ( AD ) or reduces the severity of AD in newborns to children younger than 3 years .