The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .
[Efficacy of a triclosan/copolymer dentifrice in the control of plaque and gingivitis: a six-month study in China].
A total of one hundred fifty three healthy male and female adults were entered into a six month , double-blind clinical study design ed to evaluate the effect of a dentifrice containing 0.3 % triclosan and 2.0 % PVM/MA copolymer in a 0.243 % sodium fluoride/silica base , relative to a 0.243 % sodium fluoride silica base control dentifrice on supragingival plaque accumulation and gingivitis . Plaque and gingivitis were scored after 3 and 6 months ' use of the assigned dentifrice . At the end of the study , the dentifrice containing triclosan/copolymer demonstrated an average reduction , relative to the control dentifrice of 16.1 % in plaque accumulation and 24.3 % in gingivitis . Both were statistically significant(P < 0.001 ) . It was concluded that the twice-daily use of the triclosan/copolymer containing dentifrice result ed in a significant reduction in plaque formation and a significant improvement in gingival health . No side-effects were observed
The studies in this systematic review provide strong evidence of the antiplaque , antigingivitis effects of multiple agents .
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of  antigingivitis and antiplaque products  in six-month trials .