In healthy subjects , appetite and short term food intake , risk of cancer , risk of diabetes , risk of dental caries , weight gain and risk of obesity are the most investigated health outcomes .
Overall there is no conclusive evidence for beneficial and harmful effects on those outcomes .
In subjects with diabetes and hypertension , the evidence regarding health outcomes of NNS use is also inconsistent .
Background Food products containing non-nutritive sweeteners ( NNSs ) instead of sugar have become increasingly popular in the last decades .
Their appeal is obviously related to their calorie-free sweet taste .
However , with the dramatic increase in their consumption , it is reasonable and timely to evaluate their potential health benefits and , more importantly , potential adverse effects .
The main aim of this scoping review was to map the evidence about health outcomes possibly associated with regular NNS consumption by examining the extent , range , and nature of research activity in this area .
A randomized control trial for reduction of caloric and non-caloric sweetened beverages in young adults: effects in weight, body composition and blood pressure.
INTRODUCTION Recently has been documented that the consumption of sweetened non-caloric beverages has increased as an option to weight control , however r and omized control trials have demonstrated a modest weight loss . OBJECTIVE To evaluate the effect of reducing consumption of beverage with caloric and non-caloric sweeteners on weight , body composition and blood pressure  in young Mexican adults . METHODS In an experimental study 148 nursing students were r and omly assigned to one of 3 groups : 1 ) no sweetened beverages were permitted , only plain water , tea or coffee without sugar ; 2 ) consumption of beverages with non-caloric sweeteners was allowed ; and 3 ) no restriction of sweetened beverages was imposed . All groups were given individualized isocaloric diets monitored by a 24-hour record of consumption and food frequency question naire and blood pressure , weight , waist circumference and body composition by tetrapolar bioelectric impedance were taken at the beginning of the study and three and six months later . RESULTS Differences between groups were found in body mass index at 3 months that decrease in group 1 and 2 and increase in group 3 ( -1.75 vs.-0.61 vs.0.54 % of change , p < 0.001 ) . At six months there were also statistical differences in waist circumference ( -4.07 vs.-1.23 vs. 0.62 % of change , p < 0.001 ) and sugar consumption ( -62.0 vs.-54.61 vs.11.08 % of change , p < 0.001 ) in groups 1 , 2 and 3 respectively . CONCLUSIONS The reduction in consumption of both caloric and non-caloric sweetened beverages contributes to signifi ca nt body mass index loss and waist circumference
In healthy subjects , appetite and short term food intake , risk of cancer , risk of diabetes , risk of dental caries , weight gain and risk of obesity are the most investigated health outcomes .
Overall there is no conclusive evidence for beneficial and harmful effects on those outcomes .
In subjects with diabetes and hypertension , the evidence regarding health outcomes of NNS use is also inconsistent .
Background Food products containing non-nutritive sweeteners ( NNSs ) instead of sugar have become increasingly popular in the last decades .
Their appeal is obviously related to their calorie-free sweet taste .
However , with the dramatic increase in their consumption , it is reasonable and timely to evaluate their potential health benefits and , more importantly , potential adverse effects .
The main aim of this scoping review was to map the evidence about health outcomes possibly associated with regular NNS consumption by examining the extent , range , and nature of research activity in this area .