There is not sufficient evidence yet available to base recommendations for or against the use of physiotherapy interventions for ankylosing spondylitis
BACKGROUND Ankylosing spondylitis ( AS ) is a chronic rheumatic disease .
Due to the consequences of the disease , physiotherapy is regarded to be an important part of the treatment .
OBJECTIVES The objective is to summarise the available scientific evidence on the effectiveness of physiotherapy interventions in the management of AS .
Publication bias and clinical trials.
A study was performed to evaluate the extent to which the medical literature may be misleading as a result of selective publication of r and omized clinical trials ( RCTs ) with results showing a statistically significant treatment effect . Three hundred eighteen authors of published trials were asked whether they had participated in any unpublished RCTs .  The 156 respondents reported 271 unpublished and 1041 published trials . Of the 178 completed unpublished RCTs with a trend specified , 26 ( 14 % ) favored the new therapy compared to 423 of 767 ( 55 % ) published reports ( p less than 0.001 ) . For trials that were completed but not published , the major reasons for nonpublication were " negative " results and lack of interest . From the data provided , it appears that nonpublication was primarily a result of failure to write up and su bmi t the trial results rather than rejection of su bmi tted manuscripts . The results of this study imply the existence of a publication bias of importance both to meta- analysis and the interpretation of statistically significant positive trials
There is not sufficient evidence yet available to base recommendations for or against the use of physiotherapy interventions for ankylosing spondylitis
BACKGROUND Ankylosing spondylitis ( AS ) is a chronic rheumatic disease .
Due to the consequences of the disease , physiotherapy is regarded to be an important part of the treatment .
OBJECTIVES The objective is to summarise the available scientific evidence on the effectiveness of physiotherapy interventions in the management of AS .