RESULT ( S ) For infants , studies on psychomotor development showed no deficits , but few investigated cognitive or behavioral development .
Studies on toddlers generally reported normal cognitive , behavioral , socio-emotional , and psychomotor development .
For children in middle childhood , development seems comparable in children born after assisted reproduction and controls , although fewer studies have been conducted with follow-up to this age .
( S ) It may tentatively be concluded that the neurodevelopment of children born after  fertility treatment  is overall comparable to that in children born after spontaneous conception
OBJECTIVE To systematic ally review the existing literature on neurodevelopmental outcomes in children born after medically assisted reproduction  compared with those of children born after spontaneous conception .
Psychological follow-up of children born after in-vitro fertilization.
We have studied from birth up to the 3rd year the psychological attitude of 33 in-vitro fertilization ( IVF ) children compared to two other groups : children born after ovarian stimulation without IVF ( n = 33 ) and children conceived naturally ( n = 33 ) during the same period . Fourteen children , born by oocyte donation , were also studied by the same methodology . In the IVF group , we found some feeding difficulties and sleep disorders in the infants at 9 months and some signs of depression in mothers . All these symptoms disappeared afterwards . The development of all the children is satisfactory and the relationship with their mother is excellent . In this preliminary study , we conclude that the method of assisted reproduction has no bad influence on the psychomotor development of these children
RESULT ( S ) For infants , studies on psychomotor development showed no deficits , but few investigated cognitive or behavioral development .
Studies on toddlers generally reported normal cognitive , behavioral , socio-emotional , and psychomotor development .
For children in middle childhood , development seems comparable in children born after assisted reproduction and controls , although fewer studies have been conducted with follow-up to this age .
( S ) It may tentatively be concluded that the neurodevelopment of children born after  fertility treatment  is overall comparable to that in children born after spontaneous conception
OBJECTIVE To systematic ally review the existing literature on neurodevelopmental outcomes in children born after medically assisted reproduction  compared with those of children born after spontaneous conception .