For most comparisons , the credibility of evidence was rated very low to moderate , with the exception for the DASH vs. the low-fat dietary approach for which the quality of evidence was rated high .
Conclusion : The present network meta- analysis suggests that the DASH dietary approach might be the most effective dietary measure to reduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
ABSTRACT Background : Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood pressure but their comparative effects have not been established .
Objective : Therefore we performed a systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects through network meta- analysis including hypertensive and pre-hypertensive patients .
The effects of a 6-month sodium restriction on cardiac autonomic function in patients with mild to moderate essential hypertension.
BACKGROUND The blood pressure-lowering mechanism of low-sodium diet is not fully understood . METHODS We assessed the effects of salt restriction on cardiac parasympathetic function as measured by heart-rate variability ( HRV ) in mild to moderate hypertensive patients . Eighty patients were r and omized to a 6-month low- ( N = 40 ) or normal ( N = 40 ) sodium diet and a 24-h electrocardiogram ( ECG ) was carried out in the beginning of the study and at 6 months . Five time-domain and six frequency-domain HRV variables were analyzed : mean RR interval , st and ard deviation of normal RR intervals , mean of the st and ard deviations of all RR intervals for 5-min segments of the entire recording , percentage of differences between adjacent normal RR intervals exceeding 50 ms , square root of the mean of squared differences between adjacent normal RR intervals , total ( 0.01 - 0.40 Hz ) , high frequency ( HF , 0.15 - 0.40 Hz ) , low frequency ( LF , 0.04 - 0.15 Hz ) , very LF ( 0.01 - 0.04 Hz ) and LF/HF ratio . RESULTS Although blood pressure diminished significantly ( systolic blood pressure ( SBP ) from 149.9 + /- 14.7 mm Hg to 130.3 + /- 11.8 mm Hg , P < 0.001 and diastolic blood pressure ( DBP ) from 98.0 + /- 6.4 mm Hg to 87.1 + /- 6.2 mm Hg , P < 0.001 ) after 6 months in the salt reduction group , no significant differences in the change between the groups could be detected . CONCLUSIONS A moderate , prolonged dietary sodium restriction does not alter HRV . Therefore , mechanisms other than cardiac autonomic mechanisms are likely to predominate in the blood pressure-lowering effect of salt restriction
For most comparisons , the credibility of evidence was rated very low to moderate , with the exception for the DASH vs. the low-fat dietary approach for which the quality of evidence was rated high .
Conclusion : The present network meta- analysis suggests that the DASH dietary approach might be the most effective dietary measure to reduce blood pressure among hypertensive and pre-hypertensive patients based on high quality evidence
ABSTRACT Background : Pairwise meta-analyses have shown beneficial effects of individual dietary approaches on blood pressure but their comparative effects have not been established .
Objective : Therefore we performed a systematic review of different dietary intervention trials and estimated the aggregate blood pressure effects through network meta- analysis including hypertensive and pre-hypertensive patients .