Levels of other adipocytokines were not significantly affected .
CONCLUSION Eicosapentaenoic acid and docosahexaenoic acid supplementation may increase adiponectin and reduce TNF-α levels in this population group .
BACKGROUND The objective of this systematic review and meta- analysis was to determine the effects of omega-3 supplementation on adipocytokine levels in adult prediabetic and diabetic individuals .
Incidence of diabetes and serum adipokines in Catalonian men. The ADIPOCAT study
Aims . To investigate the relationship of body mass index and serum adipokines with  incidence of diabetes in men . Material and methods . Ten-year cohort study of a r and om population sample of 1011 men aged 35–69 years from the MONICA-Catalonia survey ( 1986–1988 ) . WHO-MONICA protocol and the US Hispanic NHANES diabetes question naire were applied .  Fasting serum glucose and lipids were measured by enzymatic methods , adipokines and insulin by Luminex xMAP technology , and hs-CRP by nephelometry in stored baseline sample s ( –80 ° C ) . Type2 diabetes was defined as fasting glucose ≥ 7.0 mmol/L or diagnosed diabetes . Incident diabetes was defined as absence of these criteria at baseline but presence at re-examination . Cox regression analysis was used . Results . Incidence of diabetes ( n = 85 ) was 10.3/1000 person-years , increasing significantly with BMI but decreasing by quartiles of adiponectin . Incidence increased above median BMI and glucose ( 45.3/1000 person-years , OR = 19.97 ) . Log-adiponectin associated with reduced risk of diabetes after multivariate adjustment ( HR = 0.24 , 95 % CI 0.08–0.72 ) , with significant modification of this effect by baseline glycaemia . C-reactive protein was not a significant factor . Leptin lost strength when adjusted for BMI . Conclusions . In a population with relatively high diabetes incidence , BMI and glucose were strong risk factors , while adiponectin protected against diabetes , especially in men with high glycaemic level
Levels of other adipocytokines were not significantly affected .
CONCLUSION Eicosapentaenoic acid and docosahexaenoic acid supplementation may increase adiponectin and reduce TNF-α levels in this population group .
BACKGROUND The objective of this systematic review and meta- analysis was to determine the effects of omega-3 supplementation on adipocytokine levels in adult prediabetic and diabetic individuals .