A similar effect has been found in chronic pelvic inflammatory disease .
The review also revealed that  balneotherapy has some beneficial effects on antioxidant status , and on metabolic and inflammatory parameters .
Based on the results , we conclude that balneotherapy with Hungarian thermal-mineral waters is an effective remedy for  lower back pain  , as well as for knee and h and osteoarthritis
Balneotherapy is appreciated as a traditional treatment modality in medicine .
Hungary is rich in thermal mineral waters .
Balneotherapy has been in extensive use for centuries and its effects have been studied in detail .
Clinical and microcirculatory effects of transcutaneous CO2 therapy in intermittent claudication. Randomized double-blind clinical trial with a parallel design.
BACKGROUND This r and omized , double blind trial determined the short and long-term clinical and hemodynamic vasodilator effects induced by percutaneous applications of natural CO2 gas in patients with moderate Fontaine stage II . PATIENTS AND METHODS 62 patients with intermittent claudication ( 100 - 500 meters ) were r and omized to 18 consecutive days of CO2 treatment or placebo ( air ) . The gas fluids were applied at a constant temperature of 30 degrees C on pre-humidified skin . The effects of the treatment were evaluated by total distance walked ( primary criterion ) and hemodynamic and microcirculatory findings . Patients also answered a quality of life question naire . RESULTS The Str and ness test showed a significant increase in total distance walked ( + 131 meters , 66 % ; p = 0.001 ) and pain-free distance ( + 81 meters , 73 % ; p = 0.02 ) after 18 days of CO2 treatment . The improvement was maintained 3 and 12 months later . The systolic pressure index ( ABI ) increased by 37 % ( p = 0.001 ) 1 minute after treadmill walking and ABI recovery time decreased significantly by 38 % ( p = 0.002 ) . Microcirculatory findings showed an increase in systolic pressure of the great toe ( 13 % ; p < 0.0001 ) , in baseline pO2 ( 20 % ; p = 0.01 ) and in vasomotion ( 78 % ; p = 0.001 ) in the treatment group . The improvement in total walking distance was correlated with the increase in ABI and peripheral cutaneous oxygenation . Patients ' subjective assessment s corroborated the benefits . No significant change was observed in the placebo group . CONCLUSIONS This study demonstrates that 18 consecutive days of percutaneous CO2 treatment significantly increases walking distance in patients with moderate intermittent claudication . This effect , which was associated with an increase in peripheral systolic pressure and pO2 , is evidence of a better ability to withst and effort
A similar effect has been found in chronic pelvic inflammatory disease .
The review also revealed that  balneotherapy has some beneficial effects on antioxidant status , and on metabolic and inflammatory parameters .
Based on the results , we conclude that balneotherapy with Hungarian thermal-mineral waters is an effective remedy for  lower back pain  , as well as for knee and h and osteoarthritis
Balneotherapy is appreciated as a traditional treatment modality in medicine .
Hungary is rich in thermal mineral waters .
Balneotherapy has been in extensive use for centuries and its effects have been studied in detail .