Overall , the current literature supports clearly the dose-response relationship between physical activity and the seven chronic conditions identified .
Moreover , higher levels of physical activity reduce the risk for premature all-cause mortality .
The current Canadian guidelines appear to be appropriate to reduce the risk for the seven chronic conditions identified above and all-cause mortality
This systematic review examines critically the scientific basis for Canada 's Physical Activity Guide for Healthy Active Living for adults .
Particular reference is given to the dose-response relationship between physical activity and premature all-cause mortality and seven chronic diseases ( cardiovascular disease , stroke , hypertension , colon cancer , breast cancer , type 2 diabetes ( diabetes mellitus ) and osteoporosis ) .
The strength of the relationship between physical activity and specific health outcomes is evaluated critically .
Physical activity and cause-specific mortality in the Whitehall study.
A prospect i ve cohort study of London civil servants was used to examine the relation of physical activity to various causes of death .  6,702 men aged 40 - 64 y who participated in a baseline examination between 1969 and 1970 were followed up for 25 y during which time there were 2859 deaths . The association of two measures of physical activity ( leisure time activity and usual walking pace ) with cause-specific mortality was examined . Walking pace demonstrated inverse relations with mortality from all-causes , coronary heart disease ( CHD ) , other cardiovascular disease ( CVD ) , all cancers , respiratory disease , colorectal cancer and haematopoietic cancer following adjustment for risk factors which included age , employment grade , smoking , body mass index , and forced expiratory volume ( P [trend]<0.05 for all ) . In analyses restricted to men without disease at entry , walking pace retained inverse associations with all-cause , CHD , other cardiovascular disease , and haematopoietic cancer mortality ( P [trend]<0.05 for all ) .  Leisure time activity  was also inversely associated with mortality from all-causes , CHD , other CVD , and all-cancers following adjustment for risk factors ( P [trend]<0.05 for all ) . Eliminating deaths in the first 5 and 10 y of follow-up did not greatly alter these associations . It is concluded that physical activity may confer protection against death due to some cancers , in addition to reducing cardiovascular disease risk
Overall , the current literature supports clearly the dose-response relationship between physical activity and the seven chronic conditions identified .
Moreover , higher levels of physical activity reduce the risk for premature all-cause mortality .
The current Canadian guidelines appear to be appropriate to reduce the risk for the seven chronic conditions identified above and all-cause mortality
This systematic review examines critically the scientific basis for Canada 's Physical Activity Guide for Healthy Active Living for adults .
Particular reference is given to the dose-response relationship between physical activity and premature all-cause mortality and seven chronic diseases ( cardiovascular disease , stroke , hypertension , colon cancer , breast cancer , type 2 diabetes ( diabetes mellitus ) and osteoporosis ) .
The strength of the relationship between physical activity and specific health outcomes is evaluated critically .