Conclusions : Currently , there is insufficient evidence about the effects of combined aerobic and resistance exercise compared to isolated aerobic exercise or usual care on walking performance .
However , despite the low quality of evidence , the combined aerobic and resistance exercise seems to be an effective strategy to improve walking performance in patients with intermittent claudication .
These combined exercise modes or isolated aerobic exercise produce positive and significant results on walking performance .
The usual care approach has a trend to deteriorate the walking performance .
Background : The short-term benefits of aerobic and resistance exercise in subjects affected by Peripheral Arterial Disease ( PAD ) are scarcely examined in interaction .
This study aim ed to identify the effects of combined aerobic and resistance exercise programs on walking performance compared with isolated aerobic exercise or with the usual care in patients with intermittent claudication .
Association between oxidative stress index and post-CPR early mortality in cardiac arrest patients: A prospective observational study
Objective : Cardiopulmonary resuscitation ( CPR ) is a series of lifesaving actions that improve the chance of survival following cardiac arrest ( CA ) . Many clinical and laboratory parameters , such as the presence of asystole , out-of-hospital CPR , and duration of cardiac arrest , are associated with failed CPR in patients with CA . Asystole is a state of no cardiac electrical activity , along with the absence of contractions of the myocardium and absence of cardiac output . Oxidative stress index ( OSI ) , which is the ratio of total oxidative status to total antioxidant status , increases by ischemia-reperfusion injury . We investigated whether OSI levels in patients with CA could predict early mortality after CPR . Methods : This study has a prospect i ve observational cohort design . Five patients with a history of cancer , four patients who developed hemolysis in their blood , six patients who were transferred to our hospital from other hospitals , and six patients in whom blood sample s for OSI could not be stored properly were excluded . Finally , a total of 90 in-hospital or out-of-hospital CA patients and 40 age- and sex-matched healthy volunteers as the control group were evaluated prospect ively . The patients were classified according to the CPR response into a successful group ( n=46 ) and a failed group ( n=44 ) . Comparisons between groups were performed using one-way ANOVA with post hoc analysis by Tukey ’s HSD or independent sample s t-test and the Kruskal-Wallis tests or Mann-Whitney U test for normally and abnormally distributed data , respectively . Also , we used chi-square test , Spearman ’s correlation test , univariate and multible logistic regression analyses , and receiver operator characteristic curve analysis . Results : OSI was 3.0±4.0 , 5.6±4.3 , and 8.7±3.8 in the control group , the successful CPR group , and the failed CPR group , respectively ( p<0.001 for the 2 comparisons ) . OSI on admission , ischemia-modified albumin , presence of asystole , mean duration of cardiac arrest , out-of-hospital CPR , pH , and potassium and sodium levels were found to have prognostic significance in the univariate analysis . In the multivariate logistic regression model , OSI on admission ( OR=1.325 , p=0.003 ) , ischemia-modified albumin ( OR=1.008 , p=0.005 ) , presence of asystole ( OR=13.576 , p<0.001 ) , and sodium level ( OR=1.132 , p=0.029 ) remained associated with an increased risk of early mortality . In addition , the optimal cut-off value of OSI to predict post-CPR mortality was measured as > 6.02 , with 84.1 % sensitivity and 76.1 % specificity . Conclusion : Elevated OSI levels can predict failed CPR in CA patients
Conclusions : Currently , there is insufficient evidence about the effects of combined aerobic and resistance exercise compared to isolated aerobic exercise or usual care on walking performance .
However , despite the low quality of evidence , the combined aerobic and resistance exercise seems to be an effective strategy to improve walking performance in patients with intermittent claudication .
These combined exercise modes or isolated aerobic exercise produce positive and significant results on walking performance .
The usual care approach has a trend to deteriorate the walking performance .
Background : The short-term benefits of aerobic and resistance exercise in subjects affected by Peripheral Arterial Disease ( PAD ) are scarcely examined in interaction .
This study aim ed to identify the effects of combined aerobic and resistance exercise programs on walking performance compared with isolated aerobic exercise or with the usual care in patients with intermittent claudication .