Pooled net change in systolic blood pressure ( 16 trials ) was -1.86 ( 95 % CI -3.17 to -0.55 ; p=0.01 ) mm Hg ; diastolic blood pressure ( 15 trials ) , -1.53 ( -2.43 to -0.62 ; p=0.001 ) mm Hg ; body mass index ( 14 trials ) , -0.13 ( -0.26 to -0.01 ; p=0.04 ) kg/m2 ; serum total cholesterol ( 14 trials ) , -0.13 ( -0.19 to -0.07 ; p<0.001 ) mmol/L. There was no significant association between interventions with a reported theoretical basis and improved intervention outcomes .
No association was observed between intervention intensity ( number of sessions and intervention duration ) and intervention outcomes .
MHBC interventions delivered to CVD-free participants in primary care did not appear to have quantitatively important effects on CVD risk factors .
BACKGROUND It is uncertain whether multiple health behaviour change ( MHBC ) interventions are effective for the primary prevention of cardiovascular disease ( CVD ) in primary care .
Randomised controlled trial evaluating cardiovascular screening and intervention in general practice: principal results of British family heart study. Family Heart Study Group.
OBJECTIVE To measure the change in cardiovascular risk factors achievable in families over one year by a cardiovascular screening and lifestyle intervention in general practice . DESIGN R and omised controlled trial in 26 general practice s in 13 towns in Britain . SUBJECTS 12,472 men aged 40 - 59 and their partners ( 7460 men and 5012 women ) identified by household . INTERVENTION Nurse led programme using a family centred approach with follow up according to degree of risk . MAIN OUTCOME MEASURES After one year the pairs of practice s were compared for differences in ( a ) total coronary ( Dundee ) risk score and ( b ) cigarette smoking , weight , blood pressure , and r and om blood cholesterol and glucose concentrations . RESULTS In men the overall reduction in coronary risk score was 16 % ( 95 % confidence interval 11 % to 21 % ) in the intervention practice s at one year . This was partitioned between systolic pressure ( 7 % ) , smoking ( 5 % ) , and cholesterol concentration ( 4 % ) . The reduction for women was similar . For both sexes reported cigarette smoking at one year was lower by about 4 % , systolic pressure by 7 mm Hg , diastolic pressure by 3 mm Hg , weight by 1 kg , and cholesterol concentration by 0.1 mmol/l , but there was no shift in glucose concentration . Weight , blood pressure , and cholesterol concentration showed the greatest difference at the top of the distribution . If maintained long term the differences in risk factors achieved would mean only a 12 % reduction in risk of coronary events . CONCLUSIONS As most general practice s are not using such an intensive programme the changes in coronary risk factors achieved by the voluntary health promotion package for primary care are likely to be even smaller . The government 's screening policy can not be justified by these results
Pooled net change in systolic blood pressure ( 16 trials ) was -1.86 ( 95 % CI -3.17 to -0.55 ; p=0.01 ) mm Hg ; diastolic blood pressure ( 15 trials ) , -1.53 ( -2.43 to -0.62 ; p=0.001 ) mm Hg ; body mass index ( 14 trials ) , -0.13 ( -0.26 to -0.01 ; p=0.04 ) kg/m2 ; serum total cholesterol ( 14 trials ) , -0.13 ( -0.19 to -0.07 ; p<0.001 ) mmol/L. There was no significant association between interventions with a reported theoretical basis and improved intervention outcomes .
No association was observed between intervention intensity ( number of sessions and intervention duration ) and intervention outcomes .
MHBC interventions delivered to CVD-free participants in primary care did not appear to have quantitatively important effects on CVD risk factors .
BACKGROUND It is uncertain whether multiple health behaviour change ( MHBC ) interventions are effective for the primary prevention of cardiovascular disease ( CVD ) in primary care .