Available evidence from this systematic review suggests that high dose vitamin D may prevent  asthma exacerbation .
CONTEXT Observational studies have suggested a relationship between vitamin D status and asthma-related respiratory outcomes .
The benefit of vitamin D supplementation for pulmonary function , symptoms and exacerbations is not well established .
OBJECTIVE To systematic ally review paediatric clinical trials investigating the role of vitamin D on asthma-related respiratory outcomes .
[Prophylaxis of vitamin D deficiency in hypothyroidism in the newborn infant].
This study deals with the relationship between the occurrence of hypercalcemia and the administration of prophylactic doses of vitamin D in children with hypothyroidism , before and during L-thyroxine ( LT4 ) treatment .  The goal of the study was to determine the dosage of vitamin D necessary to prevent rickets without inducing hypercalcemia . There was a 23 % prevalence of hypercalcemia at the time of the diagnosis of hypothyroidism by screening whereas it was 21 % in the children who were not given vitamin D  during the first 3 months of LT4 treatment . This figure was significantly higher in those who were given vitamin D during the first 3 months of treatment and reached 70 % . However , one of the 19 children not given vitamin D presented with biological signs evoking vitamin D deficiency . In conclusion , in hypothyroid infants , vitamin D should be administered carefully during the first 6 months of treatment and restricted to children at risk for developing vitamin D deficiency
Available evidence from this systematic review suggests that high dose vitamin D may prevent  asthma exacerbation .
CONTEXT Observational studies have suggested a relationship between vitamin D status and asthma-related respiratory outcomes .
The benefit of vitamin D supplementation for pulmonary function , symptoms and exacerbations is not well established .
OBJECTIVE To systematic ally review paediatric clinical trials investigating the role of vitamin D on asthma-related respiratory outcomes .