Conclusion Based on available literature , evidence suggests that community-based interventions may reduce the incidence rate of T2DM and may positively affect anthropometric indices and HbA1C .
Due to the heterogeneity observed between trials we recommend more well- design ed RCTs with longer follow-up duration s be executed , to confirm whether community-based interventions lead to reduced T2DM events in the at-risk population of LMIC setting
Background The increasing prevalence of type 2 diabetes mellitus ( T2DM ) can have a substantial impact in low- and middle-income countries ( LMICs ) .
Community-based programs addressing diet , physical activity , and health behaviors have shown significant benefits on the prevention and management of T2DM , mainly in high-income countries .
However , their effects on preventing T2DM in the at-risk population of LMICs have not been thoroughly evaluated .
One-Year Results of a Synthetic Intervention Model for the Primary Prevention of T2D among Elderly Individuals with Prediabetes in Rural China
Objective : The objective of this study was to evaluate the effectiveness of a synthetic intervention model aim ed at preventing type 2 diabetes and controlling plasma glucose , body weight and waist circumference in elderly individuals with prediabetes in rural China . Methods : We r and omly assigned 434 ( 180 men and 254 women ; mean age , 69 years ; mean body mass index , 23.6 kg/m2 ) with prediabetes to either the intervention group or the control group . Each participant in the intervention group received synthetic intervention for 1 year . Results : The incidence of diabetes was 4.2 % in the intervention group , versus 19.7 % in the control group at the end of 1 year ( p < 0.001 ) . Compared with the control group , the intervention group experienced a great decrease in fasting glucose ( −3.9 vs. 2.2 mg/dL , p < 0.001 ) , body weight ( −3.2 vs. 1.7 kg , p < 0.001 ) , waist circumference ( −2.4 vs. 1.0 cm , p < 0001 ) , total cholesterol ( −9.1 vs. −4.6 mg/dL. p = 0.014 ) and HbA1c ( −1.0 vs. 0.1 mg % , p = 0.002 ) at the end of 1 year . Conclusions : The incidence of diabetes of the control group was higher than that of the intervention group . Besides , the synthetic intervention contributes to weight loss and glucose decrease , and may be effective in reducing the risk of diabetes among elderly individuals with prediabetes in rural China
Conclusion Based on available literature , evidence suggests that community-based interventions may reduce the incidence rate of T2DM and may positively affect anthropometric indices and HbA1C .
Due to the heterogeneity observed between trials we recommend more well- design ed RCTs with longer follow-up duration s be executed , to confirm whether community-based interventions lead to reduced T2DM events in the at-risk population of LMIC setting
Background The increasing prevalence of type 2 diabetes mellitus ( T2DM ) can have a substantial impact in low- and middle-income countries ( LMICs ) .
Community-based programs addressing diet , physical activity , and health behaviors have shown significant benefits on the prevention and management of T2DM , mainly in high-income countries .
However , their effects on preventing T2DM in the at-risk population of LMICs have not been thoroughly evaluated .