Conclusion We present clear evidence for the benefit of probiotics and synbiotics supplementation  for liver steatosis , liver enzymes , lipid profiles and liver stiffness in patients with NAFLD
Background and Aim Extensive epidemiological evidence suggests that nonalcoholic fatty liver disease ( NAFLD ) is the primary chronic liver disease worldwide .
However , some studies have showed conflicting results on the effects of probiotics and synbiotics supplementation .
Therefore , we conducted a systematic review and meta- analysis to investigate the effectiveness of the supplementation in subjects with NAFLD .
Influence of non-alcoholic fatty liver disease on the development of diabetes mellitus.
BACKGROUND AND AIM Non-alcoholic fatty liver disease ( NAFLD ) is linked to metabolic syndrome , and is known to be associated with impaired fasting glycemia and diabetes mellitus . This prospect i ve community-based study was conducted to determine the association between NAFLD and incidence of diabetes mellitus  in an urban adult population in Sri Lanka . METHODS Participants of the Ragama Health Study cohort were assessed for NAFLD using established ultrasound criteria in 2007 . Those who were free of diabetes at baseline were followed up for 3 years . Incidence rates of diabetes mellitus were compared between subjects with and without NAFLD at baseline . RESULTS Out of 2984 subjects , 926 had NAFLD and 676 had diabetes in 2007 . Of the 2276 subjects who were free of diabetes in 2007 , 1914 were re-assessed in 2010 . After 3 years , 104 out of 528 subjects with NAFLD and 138 out of 1314 subjects without NAFLD had developed diabetes mellitus de novo . Incidence rates of diabetes were respectively 64.2 and 34 per 1000 person-years of follow up for those with and without NAFLD . NAFLD was an independent predictor of developing diabetes mellitus . Other independent predictors were impaired fasting glycemia and dyslipidemia . CONCLUSIONS Subjects with ultrasonically diagnosed NAFLD have an increased risk of developing diabetes mellitus . Intervention for NAFLD through lifestyle modification may prevent progression of the current diabetes epidemic
Conclusion We present clear evidence for the benefit of probiotics and synbiotics supplementation  for liver steatosis , liver enzymes , lipid profiles and liver stiffness in patients with NAFLD
Background and Aim Extensive epidemiological evidence suggests that nonalcoholic fatty liver disease ( NAFLD ) is the primary chronic liver disease worldwide .
However , some studies have showed conflicting results on the effects of probiotics and synbiotics supplementation .
Therefore , we conducted a systematic review and meta- analysis to investigate the effectiveness of the supplementation in subjects with NAFLD .