Results concerning the association of chronic physical activity and motor performance are mixed and seem to be influenced by the study design , kind of exercise , motor task , and exercise intensity .
Regarding motor learning , a high physical activity or cardiovascular fitness level seems to boost the initial phase of motor learning ; results differ with respect to motor retention .
Overall , ( motor-coordinative ) intervention studies seem to be more promising than cross-sectional studies
Upper extremity motor performance declines with increasing age .
However , older adults need to maintain , learn new and relearn known motor tasks .
Research with young adults indicated that regular and acute physical activity might facilitate motor performance and motor learning processes .
Therefore , this review aim ed to examine the association between chronic physical activity and acute bouts of exercise on motor performance and motor learning in upper extremity motor tasks in older adults .
Acute exercise improves motor memory: Exploring potential biomarkers
We have recently shown that a single bout of acute cardiovascular exercise improves motor skill learning through an optimization of long-term motor memory . Here we exp and this previous finding , to explore potential exercise-related biomarkers and their association with measures of motor memory and skill acquisition .  Thirty-two healthy young male subjects were r and omly allocated into either an exercise or control group . Following either an intense bout of cycling or rest subjects practice d a visuomotor tracking task .  Motor skill acquisition was assessed during practice and retention 1 h , 24 h and 7 days after practice . Plasma levels of brain-derived neurotrophic factor ( BDNF ) , vascular endothelial growth factor ( VEGF ) , insulin-like growth factor ( IGF-1 ) , epinephrine , norepinephrine , dopamine and lactate were analyzed at baseline , immediately after exercise or rest and during motor practice . The exercise group showed significantly better skill retention 24h and 7 days after acquisition . The concentration of all blood compounds increased significantly immediately after exercise and remained significantly elevated for 15 min following exercise except for BDNF and VEGF . Higher concentrations of norepinephrine and lactate immediately after exercise were associated with better acquisition . Higher concentrations of BDNF correlated with better retention 1 h and 7 days after practice . Similarly , higher concentrations of norepinephrine were associated with better retention 7 days after practice whereas lactate correlated with better retention 1h as well as 24 h and 7 days after practice . Thus , improvements in motor skill acquisition and retention induced by acute cardiovascular exercise are associated with increased concentrations of biomarkers involved in memory and learning processes . More mechanistic studies are required to eluci date the specific role of each biomarker in the formation of motor memory
Results concerning the association of chronic physical activity and motor performance are mixed and seem to be influenced by the study design , kind of exercise , motor task , and exercise intensity .
Regarding motor learning , a high physical activity or cardiovascular fitness level seems to boost the initial phase of motor learning ; results differ with respect to motor retention .
Overall , ( motor-coordinative ) intervention studies seem to be more promising than cross-sectional studies
Upper extremity motor performance declines with increasing age .
However , older adults need to maintain , learn new and relearn known motor tasks .
Research with young adults indicated that regular and acute physical activity might facilitate motor performance and motor learning processes .
Therefore , this review aim ed to examine the association between chronic physical activity and acute bouts of exercise on motor performance and motor learning in upper extremity motor tasks in older adults .