In regards to surgery it is recommended to perform total omentectomy since subclinic metastasis have been documented in 10 - 30 % of all cases , and systematic limphadenectomy , necessary to be able to obtain an adequate surgical staging .
Minimal invasion surgery is not a recommended procedure for the treatment of advanced ovarian cancer .
Radiotherapy can be used to palliate symptoms .
In the present , there is not a st and ardized screening method .
Diagnosis in early stages means a better survival .
Radiotherapy can be indicated to palliate symptoms
INTRODUCTION Ovarian cancer ( OC ) is the third most common gynecologic malignancy worldwide .
Most of cases it is of epithelial origin .
At the present time there is not a st and ardized screening method , which makes difficult the early diagnosis .
The 5-year survival is 90 % for early stages , however most cases present at advanced stages , which have a 5-year survival of only 5 - 20 % .
GICOM collaborative group , under the auspice of different institutions , have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia .
Until now , laparoscopy for diagnostic-staging surgery is not well known as a recommended method .
In advanced stages , primary cytoreduction is recommended as initial treatment .
Randomized study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group comparing quality of life in patients with ovarian cancer treated with cisplatin/paclitaxel versus carboplatin/paclitaxel.
PURPOSE The objective of this study was to compare the quality of life ( QoL ) of ovarian cancer patients treated with paclitaxel/carboplatin ( TC ) versus paclitaxel/cisplatin ( PT )  and to determine the impact of treatment toxicity on the various QoL domains . PATIENTS AND METHODS In this phase III trial , 798 patients with ovarian cancer stages IIB-IV were r and omly assigned to receive TC or PT .  The primary end point was progression-free survival ; secondary end points included toxicity , QoL , and response to treatment . Patients completed the European Organisation for Research and Treatment of Cancer QLQ-C30 before treatment , within 3 days before the second and the fourth chemotherapy cycle , and 3 weeks after completion of chemotherapy . RESULTS Previously reported data showed that patients undergoing TC or PT did not differ in progression-free survival and overall survival . However , the TC arm was superior , indicating a better overall QoL compared with the PT arm . Controlling for toxicity and age , a significant treatment by assessment time interaction was found for four QoL functioning scales and three symptoms scales . Patients in the TC arm showed better means scores after treatment on overall QoL ( P = .012 ) , physical functioning ( P = .012 ) , role functioning ( P = .005 ) , and cognitive functioning ( P = .024 ) , compared with the PT arm . Concerning symptom experience , patients undergoing TC showed less nausea and vomiting ( P < .001 ) , less appetite loss ( P < .001 ) , and less fatigue ( P = .033 ) after completion of treatment compared with patients undergoing PT . CONCLUSION The TC regimen achieved better QoL outcomes compared with the PT regimen . Thus , clinicians may consider replacing cisplatin with carboplatin when treating ovarian cancer patients with chemotherapy
In regards to surgery it is recommended to perform total omentectomy since subclinic metastasis have been documented in 10 - 30 % of all cases , and systematic limphadenectomy , necessary to be able to obtain an adequate surgical staging .
Minimal invasion surgery is not a recommended procedure for the treatment of advanced ovarian cancer .
Radiotherapy can be used to palliate symptoms .
In the present , there is not a st and ardized screening method .
Diagnosis in early stages means a better survival .
Radiotherapy can be indicated to palliate symptoms
INTRODUCTION Ovarian cancer ( OC ) is the third most common gynecologic malignancy worldwide .
Most of cases it is of epithelial origin .
At the present time there is not a st and ardized screening method , which makes difficult the early diagnosis .
The 5-year survival is 90 % for early stages , however most cases present at advanced stages , which have a 5-year survival of only 5 - 20 % .
GICOM collaborative group , under the auspice of different institutions , have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia .
Until now , laparoscopy for diagnostic-staging surgery is not well known as a recommended method .
In advanced stages , primary cytoreduction is recommended as initial treatment .