The content of these signals suggest that higher precision of the current systematic review results might be achieved if an up date of the current review were conducted at this point in time .
However , these signals further indicate that such systematic review up date , despite its higher precision , would only confirm the existing review conclusion that no statistically significant difference exists in the caries-preventive effect of GIC and resin-based fissure sealants .
In conclusion , this study demonstrated the modified Ottawa method as an effective tool in establishing the up date need of the systematic review .
OBJECTIVE To demonstrate the application of the modified Ottawa method by establishing the up date need of a systematic review with focus on the caries preventive effect of GIC versus resin pit and fissure sealants ;  to answer the question as to whether the existing conclusions of this systematic review are still current ; to establish whether a new up date of this systematic review was needed .
Caries-preventive effect of glass ionomer and resin-based fissure sealants on permanent teeth: An update of systematic review evidence
Background This article constitutes a partial up date of the original systematic review evidence by Yengopal et al. from 15 January 2008 ( published in the Journal of Oral Science in 2009 ) with primary focus on research quality in regard to bias risk in trials . Its aim is to up date the existing systematic review evidence from the English literature as to whether caries occurrence on pits and fissures of teeth sealed with either GIC or resin is the same . Methods In addition to the 12 trials included during the original systematic review , 5 new trials were identified during the data base search ( up to 26 August 2010 ) and 2 further trials were included from a h and search and reference check . Of these , 3 trials were excluded and 16 were accepted for data extraction and quality assessment . The quality of accepted trials was assessed , using up date d quality criteria , and the risk of bias was investigated in more depth than previously reported . In addition , the focus of quantitative synthesis was shifted to single data sets that were extracted from the accepted trials . Results Twenty-six dichotomous and 4 continuous data sets were extracted . Meta- analysis and cumulative meta- analysis were used in combining clinical ly homogenous data sets . The overall outcome of the computed data sets suggest no difference between the caries-preventive effects of GIC- and resin-based fissure sealants . Conclusions This overall outcome is in agreement with the conclusions of the original systematic review . Although the findings of the trials identified in this up date may be considered to be less affected by attrition- and publication bias , their risk of selection - and detection-/performance bias is high . Thus , verification of the currently available results requires further high quality r and omised control trials
The content of these signals suggest that higher precision of the current systematic review results might be achieved if an up date of the current review were conducted at this point in time .
However , these signals further indicate that such systematic review up date , despite its higher precision , would only confirm the existing review conclusion that no statistically significant difference exists in the caries-preventive effect of GIC and resin-based fissure sealants .
In conclusion , this study demonstrated the modified Ottawa method as an effective tool in establishing the up date need of the systematic review .
OBJECTIVE To demonstrate the application of the modified Ottawa method by establishing the up date need of a systematic review with focus on the caries preventive effect of GIC versus resin pit and fissure sealants ;  to answer the question as to whether the existing conclusions of this systematic review are still current ; to establish whether a new up date of this systematic review was needed .