Intracervical prostaglandins are effective compared to placebo, but appear inferior when compared to intravaginal prostaglandins.
[Priming of cervix with prostaglandin gel during immature birth situation at term (author's transl)].
The article reports on a controlled, randomized double-blind study by which the effect of intracervically applied Prostaglandin in F2 alpha Gel was examined with regard to the cervix during immature vaginal situation. 124 patients were included in the study. 4 of these had to be dropped because of documentation errors. Age, duration of pregnancy and percentage share of primiparae were approximately equal in both groups. The results show that administration of Prostaglandin Gel via the intracervical route can provoke birth within the next 36 hours in more than 75% of the cases. Only 12.8% of the cases belonged to this category in the control group. Results are somewhat poorer in primiparae. Coarser side effects did not occur in our group, and there is also no higher incidence of surgical deliveries. No negative influence on newborn is to be expected. Results are presented, discussed and compared with those communicated in the available literature.