This review shows a trend towards greater effectiveness with dual chamber pacing compared to single chamber ventricular pacing, which supports the current British Pacing and Electrophysiology Group's Guidelines regarding atrioventricular block. Additional randomised controlled trial evidence from ongoing trials in this area will further inform the debate.
Randomised controlled trial of physiological and ventricular pacing.
Thirteen patients have completed a randomised double blind cross over study to compare the effects of chronic ventricular and atrial synchronous pacing on exercise capacity and symptoms. Maximal symptom limited exercise was significantly increased after one month of atrial synchronous pacing compared with ventricular pacing. Symptomatic assessment (by diary card and monthly symptom scores) of "shortness of breath", "palpitation", and "general well-being" was significantly improved during the physiological pacing mode. Atrial synchronous pacing has been shown to be superior to ventricular pacing.