Metered-dose inhalers with spacer produced outcomes that were at least equivalent to nebuliser delivery. Spacers may have some advantages compared to nebulisers for children with acute asthma.
[Bronchodilation induced by fenoterol in asthmatic patients: comparison of jet nebulization and spacer device].
To compare bronchodilation attained by fenoterol administered through a jet nebulizer and through a spacer device.
                Open, randomized.
                44 adults with asthma, peak-flow rate varying between 120 and 200 l/min. Patients were divided into two groups. TREATMENT [corrected]: Group A was treated with fenoterol (2.5 mg) with saline to complete 3 ml given through a jet nebulizer; 30 minutes later, an additional dose (1 mg) was given through a 500 ml spacer. Group B was treated with the same dosage, but the spacer [corrected] was used first.
                Peak-flow meter in zero, 30 and 60 minutes.
                No significant difference in bronchodilation was seen between groups A and B.
                Fenoterol through a spacer can replace inhalation in adult asthma patients with non-severe obstruction. Lower cost and home treatment are the main advantages.