Sentence: The study objectives were to evaluate the safety , tolerability , and preliminary efficacy of multiple doses of dulanermin in combination with modified FOLFOX6 and bevacizumab in previously untreated patients with locally advanced , recurrent , or metastatic colorectal cancer .
Drug combination annotation:
[{'class': 'POS', 'spans': ['dulanermin', 'FOLFOX6', 'bevacizumab'], 'is_context_needed': True}]