Sentence: In contrast , the combination of plumbagin with AR antagonists , such as bicalutamide and enzalutamide , showed no improvement over AR antagonists alone .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['bicalutamide', 'plumbagin'], 'is_context_needed': True}, {'class': 'COMB', 'spans': [1, 2], 'is_context_needed': True}]