Sentence: This synergy was abrogated through siRNA knockdown of IkB. The synergistic effect of combining selinexor and bortezomib in vitro provides rationale for further investigation of this combination treatment for patients with high-risk neuroblastoma .
Drug combination annotation:
[{'class': 'POS', 'spans': ['selinexor', 'bortezomib'], 'is_context_needed': False}]