Sentence: The risk increased when ASA was combined with clopidogrel , compared with aspirin alone ( OR , 1.86 ; 95 % CI , 1.49 - 2.31 ) , anticoagulants vs low doses of ASA alone ( OR , 1.93 ; 95 % CI , 1.42 - 2.61 ) , or in studies that included patients with a history of GI bleeding or of longer duration .
Drug combination annotation:
[{'class': 'NEG', 'spans': ['clopidogrel', 'ASA'], 'is_context_needed': False}]