Sentence: Despite systemic chemotherapy combining pemetrexed , bevacizumab and Cisplatinum , the disease relapsed eight months later with multiple metastatic lung nodules leading to a treatment shift .
Drug combination annotation:
[{'class': 'NEG', 'spans': ['pemetrexed', 'bevacizumab', 'Cisplatinum'], 'is_context_needed': False}]