Sentence: Fifty-one HIV-negative patients with an average age of 50.3 years were treated with chemotherapy regimen included 2500 mg/m(2 ) MTX with Leucovorin rescue and 1.4 mg/m(2 ) vincristine ( day two ) , which was administered every other week for 6 weeks .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['Leucovorin', 'vincristine'], 'is_context_needed': True}]