Sentence: Simultaneous treatment with gefitinib and pemetrexed enhanced cell growth inhibition and cell death and prevented the appearance of gefitinib resistance mediated by T790 M mutation or epithelial-to-mesenchymal transition ( EMT ) in PC9 and HCC827 cells , respectively .
Drug combination annotation:
[{'class': 'POS', 'spans': ['gefitinib', 'pemetrexed'], 'is_context_needed': False}]