Sentence: The aim of this study was to investigate the mutagenic and antigenotoxic effects of different doses of the flavonoid , apigenin , alone and in combination with the antitumor drugs , cyclophosphamide and doxorubicin , in vitro and in vivo .
Drug combination annotation:
[{'class': 'POS', 'spans': ['apigenin', 'doxorubicin'], 'is_context_needed': True}, {'class': 'POS', 'spans': [0, 1], 'is_context_needed': True}]