Sentence: The combination of a fluoropyrimidine ( 5-fluorouracil or capecitabine ) with either oxaliplatin or irinotecan has been widely accepted as standard cytotoxic chemotherapy for either the first- or second-line treatment of mCRC .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['fluoropyrimidine', 'oxaliplatin'], 'is_context_needed': True}, {'class': 'COMB', 'spans': [0, 2], 'is_context_needed': True}]