Sentence: In the metastatic setting , FOLFIRINOX ( folinic acid , 5-fluorouracil , irinotecan , and oxaliplatin ) , and nab-paclitaxel plus gemcitabine have yielded only modest improvements in survival .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['folinic', '5-fluorouracil', 'irinotecan', 'oxaliplatin'], 'is_context_needed': True}, {'class': 'COMB', 'spans': [4, 5], 'is_context_needed': True}]