Sentence: Pretreatment with NaHCO3 , NH4Cl , SKF 525A , piperonyl butoxide , progesterone , cysteamine , phenobarbital or metyrapone prior to the administration of [methyl-14C]nicotine was studied .
Drug combination annotation:
[{'class': 'POS', 'spans': ['[methyl-14C]nicotine', 'metyrapone'], 'is_context_needed': True}, {'class': 'POS', 'spans': [8, 4], 'is_context_needed': True}]