Sentence: Twenty-one Japanese colorectal cancer patients received intravenous FOLFIRI ( bolus irinotecan , folinic acid , and fluorouracil followed by 46-hour fluorouracil infusion ) followed by bevacizumab ( 5 mg/kg ) in Cycle 1 .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['irinotecan', 'folinic acid', 'fluorouracil', 'fluorouracil', 'bevacizumab'], 'is_context_needed': True}]