Sentence: A decrease in VEGF-A expression in the tumor node and salivary gland was found after monotherapy with melatonin and cyclophosphamide and , especially , after combined treatment , which proves maximum therapeutic efficiency of combined administration of chemical agents with various mechanisms of action .
Drug combination annotation:
[{'class': 'POS', 'spans': ['melatonin', 'cyclophosphamide'], 'is_context_needed': False}]