Sentence: Previously , a study of ours showed that the combination of dabrafenib and trametinib improves progression-free survival compared with dabrafenib and placebo in patients with BRAF Val600Lys/Glu mutation-positive metastatic melanoma .
Drug combination annotation:
[{'class': 'POS', 'spans': ['dabrafenib', 'trametinib'], 'is_context_needed': False}]