Sentence: Gemcitabine with cyclosporine or with tacrolimus exerts a synergistic effect and induces tolerance in the rat .
Drug combination annotation:
[{'class': 'POS', 'spans': ['Gemcitabine', 'cyclosporine'], 'is_context_needed': False}, {'class': 'POS', 'spans': [0, 2], 'is_context_needed': False}]