Sentence: Suggested evidence linking the association of the drug to the event includes knowing that Panitumumab and Irinotecan can contribute to all other possible causes of cardiac arrest , temporal relationship and pharmacological time plausibility , and recognized association with the product or the class .
Drug combination annotation:
[{'class': 'NEG', 'spans': ['Panitumumab', 'Irinotecan'], 'is_context_needed': False}]