Sentence: Objective and palliative effect of chemotherapy is marked for weekly doxorubicin , prednisone with mitoxantrone and etoposide associated with platin-salts for prostatic carcinoma with neuroendocrine differentiation .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['doxorubicin', 'prednisone', 'mitoxantrone', 'etoposide'], 'is_context_needed': True}]