Sentence: Treatment-naive patients with nonmetastatic N2 or N3 SCCHN were randomly assigned to CRT alone ( CRT arm ; docetaxel , fluorouracil , and hydroxyurea plus radiotherapy 0.15 Gy twice per day every other week ) versus two 21-day cycles of IC ( docetaxel 75 mg/m(2 ) on day 1 , cisplatin 75 mg/m(2 ) on day 1 , and fluorouracil 750 mg/m(2 ) on days 1 to 5 ) followed by the same CRT regimen ( IC + CRT arm ) .
Drug combination annotation:
[{'class': 'NEG', 'spans': ['docetaxel', 'cisplatin', 'fluorouracil'], 'is_context_needed': True}, {'class': 'POS', 'spans': [0, 1, 2], 'is_context_needed': True}]