Sentence: To compare efficacy and toxicity of bolus application of chemotherapy protocol , oxaliplatin , fluorouracil ( bolus ) , leucovorin ( folfox ) between two groups of patients in the therapy of metastatic colorectal carcinoma ( mCRC ) .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['oxaliplatin', 'fluorouracil', 'leucovorin'], 'is_context_needed': True}]