Sentence: The first trial was a multicenter randomized phase III study of chemotherapy ( doxorubicin/cyclophosphamide or paclitaxel ) + /- trastuzumab , and the second was a multicenter phase II trial of vinorelbine + trastuzumab .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['doxorubicin/cyclophosphamide', 'trastuzumab'], 'is_context_needed': True}, {'class': 'COMB', 'spans': [1, 2], 'is_context_needed': True}, {'class': 'COMB', 'spans': [3, 4], 'is_context_needed': True}]