Sentence: Cyclophosphamide , methotrexate , 5-fluorouracil , and folinic acid ( CMFF ) as first line chemotherapy for treatment of advanced breast cancer .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['Cyclophosphamide', 'methotrexate', '5-fluorouracil', 'folinic acid'], 'is_context_needed': True}]