Sentence: In patients who experience disease progression after etoposide , doxorubicin , cisplatin with mitotane ( EDP-M ) , gemcitabine and metronomic capecitabine , or the less used streptozotocin , represent a second-line chemotherapy option .
Drug combination annotation:
[{'class': 'POS', 'spans': ['gemcitabine', 'capecitabine'], 'is_context_needed': False}, {'class': 'POS', 'spans': [4, 6], 'is_context_needed': False}]