Sentence: The present work is concerned with simultaneous determination of cefepime ( CEF ) and the co-administered drug , levofloxacin ( LEV ) , in spiked human plasma by applying a new approach , Savitzky-Golay differentiation filters , and combined trigonometric Fourier functions to their ratio spectra .
Drug combination annotation:
[{'class': 'POS', 'spans': ['cefepime', 'levofloxacin'], 'is_context_needed': False}]