Sentence: This trial will close to accrual in September 1995 , and analysis of the trial should provide useful information regarding the potential synergy of doxorubicin and paclitaxel , the degree of cross-resistance between the two compounds , and the relationship between steady-state paclitaxel levels and response to therapy .
Drug combination annotation:
[{'class': 'POS', 'spans': ['doxorubicin', 'paclitaxel'], 'is_context_needed': False}]