Sentence: In the large-scale trials carried out in Tanganyika and described in this paper , such a combination , containing amodiaquine for schizontocidal effect and primaquine as a gametocytocide , was administered to three distinct population groups of more than 5000 at differing intervals of time , in order to determine the ability of this combination to interfere with transmission in the absence of other malaria control measures .
Drug combination annotation:
[{'class': 'COMB', 'spans': ['amodiaquine', 'primaquine'], 'is_context_needed': True}]