Sentence: Subsequent investigation of therapeutic responsiveness upon treatment with the current systemic gold standard EDP-M ( etoposide , doxorubicin , cisplatin and mitotane ) demonstrated maintenance of the clinically observed drug resistance for MUC-1 exclusively .
Drug combination annotation:
[{'class': 'POS', 'spans': ['etoposide', 'doxorubicin', 'cisplatin', 'mitotane'], 'is_context_needed': True}]