Sentence: Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial .
Drug combination annotation:
[{'class': 'POS', 'spans': ['doxorubicin', 'cyclophosphamide', 'paclitaxel'], 'is_context_needed': True}, {'class': 'NEG', 'spans': [0, 1, 2, 3], 'is_context_needed': True}]