Sentence: These data suggest that vorinostat and doxorubicin may induce procoagulant activity in vessels through apoptosis of tumor cells and through phosphatidylserine exposure and/or tissue factor expression on vascular endothelial cells .
Drug combination annotation:
[{'class': 'NEG', 'spans': ['vorinostat', 'doxorubicin'], 'is_context_needed': True}]