Question: What did Susan Gottesman aid in the main research purpose at NCI?

Context paragraphs:
Douglas R. Lowy: Douglas R. Lowy (born 1940s) is the Acting Director of the U.S. National Cancer Institute (NCI) and Chief of the Laboratory of Cellular Oncology within the Center for Cancer Research at NCI.  Lowy was named Acting Director on April 1, 2015.  He was Deputy Director of the NCI from 2010 to 2015.  He was co-recipient (along with Dr. John T. Schiller) of the National Medal of Technology and Innovation in 2014.

National Biomedical Imaging Archive: National Biomedical Imaging Archive (NBIA) is an Open-source software Web application managed by the United States National Cancer Institute (NCI) intended to create searchable repositories of in vivo images.  The software is described in detail and can be downloaded from the NBIA wiki.  A re-factoring analysis which examined the current status of development and future strategies was completed in 2015 and published on the NCI wiki.  A demo instance of NBIA is deployed at http://imaging.nci.nih.gov/.  Initially this was leveraged by NCI's Cancer Imaging Program to support the data sharing needs of the cancer imaging research community, but most of that data has been migrated to The Cancer Imaging Archive (TCIA).  TCIA continues to leverage the NBIA software as part of its infrastructure.

Journal of the National Cancer Institute: The Journal of the National Cancer Institute ("JNCI") is a peer-reviewed medical journal covering research in oncology that was established in August 1940.  It is published twice per month by Oxford University Press and is edited by Carmen J. Allegra.  It was merged with Cancer Treatment Reports in January 1988.  "JNCI" used to be the official journal of the National Cancer Institute (NCI), however in 1996 the NCI and "JNCI" agreed to grow apart.  Over the next five years, "JNCI" became independent of the NCI.

Irving Gottesman: Irving Isadore Gottesman (December 29, 1930 – June 29, 2016) was an American professor of psychology who devoted most of his career to the study of the genetics of schizophrenia.  He wrote 17 books and more than 290 other publications, mostly on schizophrenia and behavioral genetics, and created the first academic program on behavioral genetics in the United States.  He won awards such as the Hofheimer Prize for Research, the highest award from the American Psychiatric Association for psychiatric research.  Lastly, Gottesman was a professor in the psychology department at the University of Minnesota, where he received his Ph.D.

Michael M. Gottesman: Michael M. Gottesman (born October 7, 1946 in Jersey City, New Jersey) is an American biochemist, the Deputy Director (Intramural) of the National Institutes of Health (NIH) in the United States, and also Chief of the Laboratory of Cell Biology at the National Cancer Institute (NCI) within the NIH.  He graduated summa cum laude in biochemical sciences in 1966 from Harvard College, and received his M.D. magna cum laude from Harvard Medical School in 1970.  He then worked as an intern and resident at the Peter Dent Brigham Hospital in Boston, a research associate at the NIH, and an assistant professor at Harvard before taking a permanent position at the NIH in 1976.

Working hypothesis: A working hypothesis is a hypothesis that is provisionally accepted as a basis for further research in the hope that a tenable theory will be produced, even if the hypothesis ultimately fails.  Like all hypotheses, a working hypothesis is constructed as a statement of expectations, which can be linked to the exploratory research purpose in empirical investigation and is often used as a conceptual framework in qualitative research.

Inderjit Dhillon: Inderjit S. Dhillon is the Gottesman Family Centennial Professor of Computer Science and Mathematics at the University of Texas at Austin, where he is also the Director of the ICES Center for Big Data Analytics.  His main research interests are in machine learning, data analysis, parallel computing, network analysis, linear algebra and optimization.

Susan Gottesman: Susan Gottesman is microbiologist at the National Cancer Institute (NCI), which is part of the National Institutes of Health (NIH).  She is a pioneer in the area of biological regulation in which enzymes that destroy specific other proteins, called proteases, play a central role inside the cell.  In groundbreaking work, she discovered and elucidated the central features of a whole new family of proteases that require energy for their function in the form of ATP-hydrolysis.  She has also played a major role in the discovery and characterization of bacterial small RNAs.

Gary L Kreps: Prior to his faculty appointment at Mason, he served for five years (1999–2004) as the founding chief of the Health Communication and Informatics Research Branch at the National Cancer Institute (National Institutes of Health), where he planned, developed, and coordinated major new national research and outreach initiatives concerning risk communication, health promotion, behavior change, technology development, and information dissemination to promote effective cancer prevention, screening, control, care, and survivorship.  During his tenure, the NCI planned and introduced the Health Information National Trends Survey and the Centers of Excellence in Cancer Communication Research.  He continues to advise the NCI and several other federal agencies (FDA, VA, CDC, AHRQ), foundations, research firms, health care delivery systems, and health product and service corporations.

National Cancer Institute: The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.  The NCI coordinates the U.S. National Cancer Program and conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship.

Supporting paragraphs: Susan Gottesman National Cancer Institute
Answer: causes, prevention, diagnosis, and treatment of cancer