Question: Hagia Irene is located in the outer courtyard of the edifice located in what Turkish capital?

Context paragraphs:
San Biagio Maggiore: The church of San Biagio Maggiore also known to its locals as 'Santa Patrizia' is a small former religious edifice located at the intersection of Via San Biagio booksellers and Via San Gregorio Armeno, which was an integral part in the city center of Naples, Italy.  It is adjacent, and for many years integral to the church of San Gennaro all’Olmo.

Serbian Church in Arad: The St. Peter and St. Paul<nowiki>'</nowiki>s Serbian Orthodox Church (Serbian: Црква светих апостола Петра и Павла / "Crkva svetih apostola Petra i Pavla" ), also known as the Serbian Church (Romanian: "Biserica Sârbească" ), is an edifice located in the city of Arad, Romania.  It was built between 1698 and 1702 and it is located in the Serbian square (Romanian: "Piata Sârbească" ).

San Gennaro all’Olmo: The deconsecrated church of San Gennaro all’Olmo is a former religious edifice located in the city center of Naples, Italy, on Via San Gregorio Armeno.  It is adjacent and for many years integral to the chapel-church of San Biagio Maggiore.

Birûn: Birûn, from the Persian word for "outside", was the term used in the Ottoman Empire to refer to the Outer Courtyard of the Topkapi Palace, as opposed to the Inner ones ("Enderûn"), which were only accessible to the Ottoman Sultan and his servants and family members.  By extension, it was also applied to the Outer Service of the palace, including also the administrative, military, and religious elite of the empire, as opposed to the Inner Service clustered around the Sultan's person.

Zwinger (fortification): A Zwinger (] ) is an open area between two defensive walls that is used for defensive purposes.  "Zwingers" were built in the Middle Ages and Early Modern Period to improve the defence of castles and town walls.  The term is German and usually left untranslated.  However, it is sometimes rendered as "outer courtyard" presumably referring to the subsequent role of a "Zwinger" as a castle's defences became redundant and it was converted into a palace or "schloss", however, this belies its original purpose as a form of killing ground for the defence.  The word is linked with "zwingen", "to force", perhaps because the "Zwinger" forced an enemy to negotiate it before assaulting the main defensive line.  Essenwein states that the ""main purpose of this feature was so that the besieging force could not reach the actual castle wall very easily with battering rams or belfries, but had to stop at the lower, outer wall; also that two ranks of archers, behind and above one another, could fire upon upon the approaching enemy""

Roznovanu Palace: Roset-Roznovanu Palace (Romanian: "Palatul Roset-Roznovanu" ) is an edifice located in Iaşi, Romania.  It was built in the second half of the 18th century, and rebuilt between 1830 and 1833 by Iordache Ruset-Roznovanu, a member of the Rosetti family.  During World War I, it hosted the Romanian government.  Today it hosts the Iași City Hall.

Hagia Irene: Hagia Irene or Hagia Eirene (Ancient Greek: Ἁγία Εἰρήνη , Byzantine ] , "Holy Peace", Turkish: "Aya İrini" ), sometimes known also as Saint Irene, is a Greek Eastern Orthodox church located in the outer courtyard of Topkapı Palace in Istanbul, Turkey.  It is one of the few churches in Istanbul that has not been converted into a mosque.  The Hagia Irene today operates as a museum and concert hall.

First Council of Constantinople: The First Council of Constantinople (Greek: Πρώτη σύνοδος της Κωνσταντινουπόλεως commonly known as Greek: Β΄ Οικουμενική , "Second Ecumenical"; Latin: "Concilium Constantinopolitanum Primum" or Latin: "Concilium Constantinopolitanum A" ) was a council of Christian bishops convened in Constantinople in AD 381 by the Roman Emperor Theodosius I.  This second ecumenical council, an effort to attain consensus in the church through an assembly representing all of Christendom, confirmed the Nicene Creed, expanding the doctrine thereof to produce the Niceno–Constantinopolitan Creed, and dealt with sundry other matters.  It met from May to July 381 in the Church of Hagia Irene and was affirmed as ecumenical in 451 at the Council of Chalcedon.

Salmon Tower Building: The Salmon Tower Building is a 31-story edifice located at 11 West 42nd Street in Manhattan which was designed by Albert J. Wilcox.  It was completed by early 1928 at which time its interior was more than 50% leased.  Salmon Tower Building was located just east of the Aeolian Building.  The firm of Walter J. Salmon, Sr. which erected the edifice, was known as 11 West 42nd Street, Inc.  It is next door to 500 Fifth Avenue, also built by Salmon, Sr.  The building has 932,101 square feet.

Topkapı Palace: The Topkapı Palace (Turkish: "Topkapı Sarayı" or in Ottoman Turkish: طوپقپو سرايى‎ , "Ṭopḳapu Sarāyı"), or the Seraglio, is a large museum in Istanbul, Turkey.  In the 15th century, it served as the main residence and administrative headquarters of the Ottoman sultans.

Supporting paragraphs: Hagia Irene Topkapı Palace
Answer: Istanbul