Question: Tom Degnan has had a recurring role on which CBS show about a drug that unlocks the full potential of the human brain, giving its user enhanced mental faculties?

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Thomas Cogswell Upham: Thomas Upham (January 30, 1799 – April 2, 1872) was an American philosopher, psychologist, pacifist, poet, author, and educator.  He was an important figure in the holiness movement.  He became influential within psychology literature and served as the Bowdoin College professor of mental and moral philosophy from 1825-1868.  His most popular work, "Mental Philosophy" received 57 editions over a 73-year period.  Additionally, he produced a volume of 16 other books and the first treatise on abnormal psychology, as well as several other works on religious themes and figures.  Specific teachings included a conception of mental faculties - one of these restoring the will to psychology be developing a tripartite division of mental phenomena into intellectual, sentient, and voluntary.  The intellect subsumed sensation and perception, attention, habit, association, and memory as well as reasoning.  Sensibilities included natural emotions and desires, such as appetites, propensities, and affections, and also moral emotions, such as a feeling of obligation.  Finally, the last division was the will, which allowed for volition as a basic component of human nature.  This positing of a will free to choose between desires and obligations reflected the author's own spiritual journey from a Calvinistic background to the Wesleyan holiness perspective.  However, perhaps his most critical contribution to the field of psychology was Upham's concept of Positive psychology which asserts that there are fundamental, transcendent laws, and living in harmony with them is the key to mental and spiritual health.  This concept laid the foundation for a healthy kind of religiosity, and a spiritually-based positive psychology.

NeuroImage: NeuroImage is a peer-reviewed scientific journal covering research on neuroimaging, including functional neuroimaging and functional human brain mapping.  The current Editor in Chief is Peter Bandettini.  Abstracts from the annual meeting of the Organization for Human Brain Mapping have been published as supplements to the journal.  Members of the Organization for Human Brain Mapping are eligible for reduced subscription rates.  In 2012, Elsevier launched an online-only, open access sister journal to "NeuroImage", entitled "".

Phi complex: The phi complex is a brain rhythm in the awake human brain that appears to serve various social functions.  Phi is one of several brain rhythms in the awake human brain that coordinate human behavior.  "Phi" operates in the 10-Hz band (ten oscillations per second), and is located above the right centro-parietal cortex.  It consists of two components, one favoring independent behaviors, and the other favoring interpersonal coordination between people.

AHI1: The Abelson helper integration site 1 (AHI1) is a protein coding gene that is known for the critical role it plays in brain development.  Proper cerebellar and cortical development in the human brain depends heavily on AHI1.  The AHI1 gene is prominently expressed in the embryonic hindbrain and forebrain.  AHI1 specifically encodes the Jouberin protein and mutations in the expression of the gene is known to cause specific forms of Joubert syndrome.  Joubert syndrome is autosomal recessive and is characterized by the brain malformations and mental retardation that AHI1 mutations have the potential to induce.  AHI1 has also been associated with schizophrenia and autism due to the role it plays in brain development.  An AHI1 heterozygous knockout mouse model was created to study the correlation between alterations in AHI1 expression and the pathogenesis of neuropsychiatric disorders.  The core temperatures and corticosterone secretions of the heterozygous knockout mice after exposure to environmental and visceral stress exhibited extreme repression of autonomic nervous system and hypothalamic-pituitary-adrenal responses.  The knockout mice demonstrated an increased resilience to different types of stress and these results lead to a correlation between emotional regulation and neuropsychiatric disorders.

BigBrain: BigBrain is a freely accessible high-resolution 3D digital atlas of the human brain, released in June 2013 by a team of researchers at the Montreal Neurological Institute and the German Forschungszentrum Jülich and is part of the European Human Brain Project.  The isotropic 3D spatial resolution of the BigBrain atlas is 20 µm, much finer than the typical 1 mm resolution of other existing 3D models of the human brain such as the Allen Brain Atlas.  In 2014, BigBrain was cited in the top 10 MIT Technology Review.

Dean Buonomano: Dean V. Buonomano is an American neuroscientist, psychologist and author.  He is a professor at UCLA whose research focuses on neurocomputation and how the brain tells time.  Buononano has been described as one of the “first neuroscientists to begin to ask how the human brain encodes time” and has been published in various scientific journals.  He is the author of two books, "Brain Bugs: How the Brain's Flaws Shape our Lives" and "Your Brain is a Time Machine: The Neuroscience and Physics of Time".  Buonomano’s first book "Brain Bugs" examines the human brain’s functional strengths and weaknesses, ultimately attributing some of the brain’s ‘bugs’ (or flaws) to evolution.

Tom Degnan: Tom Degnan (born September 24, 1982 in Bucks County, Pennsylvania) is an American actor.  He is best known for his role on "One Life to Live" as Joey Buchanan from 2010 to 2011.  He also appeared in "As the World Turns" in 2009 as Riley Morgan/Adam Munson.  Additional appearances include "Handsome Harry", alongside Steve Buscemi, and "Little Miss Perfect", alongside Lilla Crawford.  In 2013 he played the role of Fire Marshall Rick Kelly in the 10th episode of the 4th season of the CBS police procedural drama "Blue Bloods" in the episode "Mistaken Identity".  He has also played roles in the TV shows "Lipstick Jungle", "Law & Order", "The Unusuals", "The Good Wife", "White Collar", "The Following", "Magic City", "Person of Interest", "The Michael J. Fox Show", "Madam Secretary", and "The Sonnet Project".  In 2013 he played the role of Chris Van Helsing in the made-for-TV movie "Gothica" and played the role of Matt in the 2014 made-for-TV movie "Tin Man".  In 2015 he played the role of Jim in the romance-drama film "To Whom It May Concern" and played the role of Tom in the short story drama film "Seclusion".  Degnan also had a recurring role on CBS's "Limitless".

Bruce Lahn: Bruce Lahn is a Chinese-born American geneticist.  He is the William B. Graham professor of Human Genetics at the University of Chicago.  He is also the founder of the Center for Stem Cell Biology and Tissue Engineering at Sun Yat-sen University in Guangzhou, China.  His previous research specialized in human genetics and evolutionary genetics, especially human sex chromosome evolution and the genetic basis that underlies the evolutionary expansion of the human brain.  Lahn's current research interests include stem cell biology and epigenetics.  His research on the microcephaly-associated gene, MCPH1, led to the hypothesis that an archaic "Homo sapiens" lineage such as the Neanderthals might have contributed to the recent development of the human brain.  His research also suggested that newly arisen variants of two brain size genes, ASPM and MCPH1, might have been favored by positive natural selection in the recent human history.  This research provoked controversy due to the finding that the positively selected variants of these genes had spread to higher frequencies in some parts of the world than in others (for ASPM, it is higher in Europe and surrounding regions than other parts of the world; for MCPH1, it is higher outside sub-Saharan Africa than inside).  He has advocated the moral position that human genetic diversity should be embraced and celebrated as among humanity's great assets.

Yakovlevian torque: Yakovlevian torque is the tendency of the right side of the human brain to be warped slightly forward relative to the left and the left side of the human brain to be warped slightly backward relative to the right.  This is responsible for certain asymmetries, such as how the lateral sulcus of the human brain is often longer and less curved on the left side of the brain relative to the right.  It is named for Paul Ivan Yakovlev (1894–1983), a Russian-American neuroanatomist from Harvard Medical School.

Limitless (TV series): Limitless is an American comedy-drama television series based on the 2011 film of the same name, which originally aired on CBS from September 22, 2015 to April 26, 2016.  It stars Jake McDorman as Brian Finch, who discovers the power of a mysterious nootropic drug by the name of NZT-48.  This drug unlocks the full potential of the human brain and gives its user enhanced mental faculties.

Supporting paragraphs: Tom Degnan Limitless (TV series)
Answer: Limitless