Question: Reynoldsville, Illinois is located across the Mississippi River from a Missouri city that is home to what university?

Context paragraphs:
Chester Bridge: The Chester Bridge is a continuous truss bridge connecting Missouri's Route 51 with Illinois Route 150 across the Mississippi River between Perryville, Missouri and Chester, Illinois.  It is one of two motor-traffic bridges spanning the Mississippi River between St. Louis and Cape Girardeau, Missouri.

Mississippi Valley Division: The United States Army Corps of Engineers Mississippi Valley Division (MVD) is responsible for the Corps water resources programs within 370,000-square-miles of the Mississippi River Valley, as well as the watershed portions of the Red River of the North that are within the United States.  It excludes the entire watersheds of the Missouri River and Ohio River, and portions of the Arkansas River and the Red River of the South, but otherwise encompasses the entire Mississippi River from Lake Itasca, Minnesota, to the Gulf of Mexico.  The district includes all or parts of 13 states: Arkansas, Illinois, Iowa, Kentucky, Louisiana, Michigan, Minnesota, Mississippi, Missouri, North Dakota, Tennessee, Wisconsin, and South Dakota.

McKinley Bridge: The McKinley Bridge is a steel truss bridge across the Mississippi River.  It connects northern portions of the city of St. Louis, Missouri with Venice, Illinois.  It opened in 1910 and was taken out of service on October 30, 2001.  The bridge was reopened for pedestrian and bicyclists on November 17, 2007 with a grand re-opening celebration.  Since December 2007, McKinley has been open to vehicular traffic as well.  It is accessible from Illinois State Route 3 in Illinois and from the intersection of Salisbury and North 9th Street in the City of St. Louis.  The bridge carried both railroad and vehicular traffic across the Mississippi River for decades.  By 1978, the railroad line over the span was closed, and an additional set of lanes was opened for vehicles in the inner roadway.

Capes on the Mississippi River: The term cape has a different tradition of usage in the American Midwest along the Mississippi River.  The middle Mississippi River Valley once formed part of the French Colonies of Quebec and Louisiana, also referred to as Upper Louisiana (Haute-Louisiane) or the Illinois Country (Pays des Illinois).  The Illinois Country also included the left bank of the Mississippi River in present-day Missouri.

Cape Girardeau, Missouri: Cape Girardeau ( , French: "Cap-Girardeau" ] ; colloquially referred to as "Cape") is a city in Cape Girardeau and Scott counties in the U.S. state of Missouri.  It is located approximately 115 mi southeast of St. Louis and 175 mi north of Memphis.  As of the 2010 U.S. Census, the city's population was 37,941, making it the 16th-largest city in Missouri, and the largest city in Southeast Missouri.  An emerging college town, it is the home of Southeast Missouri State University.

Reynoldsville, Illinois: Reynoldsville is an unincorporated community in Union County, Illinois, United States.  The community is along Illinois Route 3 and 146, just north of McClure and across the Mississippi River from Cape Girardeau, Missouri.

American Bottom: The American Bottom is the flood plain of the Mississippi River in the Metro-East region of Southern Illinois, extending from Alton, Illinois, south to the Kaskaskia River.  It is also sometimes called "American Bottoms".  The area is about 175 sqmi , mostly protected from flooding in the 21st century by a levee and drainage canal system.  Immediately across the river from St. Louis, Missouri are industrial and urban areas, but many swamps and the major Horseshoe Lake are reminders of the Bottoms' riparian nature.  This plain served as the center for the pre-Columbian Cahokia Mounds civilization, and later the French settlement of Illinois Country.  Deforestation of the river banks in the 19th century to fuel steamboats had dramatic environmental effects in this region.  The Mississippi River between St. Louis and the confluence with the Ohio River became wider and more shallow, as unstable banks collapsed into the water.  This resulted in more severe flooding and lateral changes of the major channel, causing the destruction of several French colonial towns, such Kaskaskia, Cahokia, and St. Philippe, Illinois.

Cairo Mississippi River Bridge: The Cairo Mississippi River Bridge is a type of cantilever bridge known as a Steel Truss Through Deck carrying U.S. Route 60 and U.S. Route 62 across the Mississippi River.  Located in the tri-state area of Illinois, Kentucky, and Missouri, it connects Cairo, Illinois at its northern terminus to Bird's Point, Missouri at its southern terminus.  The bridge was most recently closed for renovation from March 16, 2015 to October 13, 2015.

Illinois Country: The Illinois Country (French: Pays des Illinois , lit.  "land of the Illinois (plural)", i.e. the Illinois people) — sometimes referred to as Upper Louisiana (French: la Haute-Louisiane ; Spanish: Alta Luisiana ) — was a vast region of New France in what is now the Midwestern United States.  While these names generally referred to the entire Upper Mississippi River watershed, French colonial settlement was concentrated along the Mississippi and Illinois Rivers in what is now the U.S. states of Illinois and Missouri, with outposts in Indiana.  Explored in 1673 from Green Bay to the Arkansas River by the "Canadien" expedition of Louis Joliet and Jacques Marquette, the area was claimed by France.  It was settled primarily from the "Pays d'en Haut" in the context of the fur trade.  Overtime, the fur trade took some French to the far reaches of the Rocky Mountains, especially along the branches of the broad Missouri River valley.  The French name, "Pays des Illinois", means "Land of the Illinois [plural]" and is a reference to the Illinois Confederation, a group of related Algonquian native peoples.

River Bend (Illinois): The River Bend is a small region in western central Illinois and Southern Illinois that comprises parts of three counties: Madison, Calhoun, and Jersey.  The name comes from a section of Mississippi River that flows roughly west to east instead of the usual north to south, causing a bend in the river.  In this area, two other major rivers, the Missouri and the Illinois join the Mississippi River.  This section of the Mississippi River is known as the Alton Lake

Supporting paragraphs: Reynoldsville, Illinois Cape Girardeau, Missouri
Answer: Southeast Missouri State University