Question: As part of Spain's effort to colonize the region and convert the Timucua people to Christianity, what Spanish Franciscan mission was build in the Florida Panhandle?

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Escambe: Escambe (also known as San Cosme y San Damián de Cupaica, San Damián de Cupaica, San Cosmo Y San Damias De Escambe, or San Damian de Cupahica) was a Spanish Franciscan mission built in the 17th century in the Florida Panhandle, three miles northwest of the present-day town of Tallahassee, Florida.  It was part of Spain's effort to colonize the region, and convert the Timucuan and Apalachee Indians to Christianity.  The mission lasted until 1704, when it was destroyed by a group of Creek Indians and South Carolinians.

San Joseph de Ocuya: San Joseph de Ocuya (also known as River Field Site) was a Spanish Franciscan mission built in the early 17th century in the Florida Panhandle, near the present-day town of Lloyd, Florida.  It was part of Spain's effort to colonize the region, and convert the Timucuan and Apalachee Indians to Christianity.  The mission lasted until the first decade of the 18th century, when it was destroyed, possibly by Creek Indians and the English.

Mission San Luis de Apalachee: Mission San Luis de Apalachee (also known as San Luis de Talimali) was a Spanish Franciscan mission built in 1633 in the Florida Panhandle, two miles west of the present-day Florida Capitol Building in Tallahassee, Florida.  It was located in the descendent settlement of Anhaica (also as Anhayca Apalache or Inihayca) capital of Apalachee Province.  The mission was part of Spain's effort to colonize the Florida Peninsula and to convert the Timucuan and Apalachee Indians to Christianity.  The mission lasted until 1704 when it was evacuated and destroyed to prevent its use by an approaching militia of Creek Indians and South Carolinians.

Santa Catalina de Guale: Santa Catalina de Guale (1602-1702) was a Spanish Franciscan mission and town in Spanish Florida.  Part of Spain's effort to convert the Native Americans to Catholicism, Santa Catalina served as the provincial headquarters of the Guale mission province.  It also served various non-religious functions, such as providing food and labor for the colonial capital of St. Augustine.  The mission was located on St. Catherines Island from 1602 to 1680, then on Sapelo Island from 1680 to 1684, and finally on Amelia Island from 1684 to 1702.

San Miguel de Asile: San Miguel de Asile was a Spanish Franciscan mission built in the early 17th century in the Florida Panhandle, near the present-day town of Lamont, Florida.  It was part of Spain's effort to colonize the region, and convert the Timucua and Apalachee people to Christianity.  The mission served a local chiefdom of the Timucua people known as the Yustaga.  It lasted until the first decade of the 18th century, when it was destroyed, possibly by Creek Indians and the English.

San Lorenzo de Ibihica: San Lorenzo de Ibihica was a Spanish Franciscan mission built in the early 17th century in the southeast of the present-day U.S. state of Georgia.  It was part of Spain's effort to colonize the region of Spanish Florida and convert the Timucua to Catholicism.  It served the Ibi people, also known as the Yui or Ibihica, a Timucua group of the area.

San Juan del Puerto, Florida: San Juan del Puerto was a Spanish Franciscan mission founded before 1587 on Fort George Island, near the mouth of the St. Johns River in what is now Jacksonville, Florida.  It was founded to serve the Saturiwa, a Timucua tribe who lived around the mouth of the St. Johns.  It was organized by separating them into nine smaller villages.  It has an important place in the study of the Timucua, as the place where Francisco Pareja undertook his work on the Timucua language.

San Pedro y San Pablo de Patale: San Pedro y San Pablo de Patale was a Spanish Franciscan mission built in the early 17th century in the Florida Panhandle, six miles east of Tallahassee, Florida.  It was part of Spain's effort to colonize the region, and convert the Timucuan and Apalachee Indians to Christianity.  The mission lasted until 1704, when it was captured by a militia of Creek Indians and South Carolinians.

Timucua: The Timucua were a Native American people who lived in Northeast and North Central Florida and southeast Georgia.  They were the largest indigenous group in that area and consisted of about 35 chiefdoms, many leading thousands of people.  The various groups of Timucua spoke several dialects of the Timucua language.  At the time of European contact, the territory occupied by speakers of Timucuan dialects occupied about 19200 sqmi , and was home to between 50,000 and 200,000 Timucuans.  It stretched from the Altamaha River and Cumberland Island in present-day Georgia as far south as Lake George in central Florida, and from the Atlantic Ocean west to the Aucilla River in the Florida Panhandle, though it reached the Gulf of Mexico at no more than a couple of points.

San Juan De Aspalaga: San Juan De Aspalaga (also known as Pine Tuft Site) was a Spanish Franciscan mission built in the early 17th century in the Florida Panhandle, near the present-day town of Wacissa, Florida.  It was part of Spain's effort to colonize the region, and convert the Timucuan and Apalachee Indians to Christianity.  The mission lasted until the first decade of the 18th century, when it was destroyed, possibly by Creek Indians and the English.

Supporting paragraphs: San Miguel de Asile Timucua
Answer: San Miguel de Asile