Question: What television series was an adaptation of a novel and had a character played by an actress who is also known for her roles on "ER" and "Desparate Housewives"?

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Joseph Sullivan (FBI): Joseph Aloysius Sullivan (February 17, 1917 – August 2, 2002) was a Major Case Inspector for the Federal Bureau of Investigation.  Born in Montreal, Wisconsin, he grew up in Hurley, Wisconsin.  He was involved in a number of highly publicized cases in the sixties and seventies including the assassination of Martin Luther King Jr., the murder of United Mine Workers reformer Joseph "Jock" Yablonski, the Sterling Hall bombing at the University of Wisconsin–Madison, and the Kent State shootings.  Despite his involvement in such high-profile cases, Sullivan is best known for his relentless search to track down the killers of three civil rights workers, who were brutally slain in Mississippi in 1964.  The character played by Willem Dafoe in the movie "Mississippi Burning" is loosely based on Sullivan.  According to "The FBI - A Comprehensive Referecie Guide" (1998), edited by Athan G. Theoharis, Sullivan was also the model for Inspector Lew Erskine, the lead character played by Efrem Zimbalist, Jr., on the TV series "The FBI".

Betty Applewhite: Betty Applewhite is a fictional character played by actress Alfre Woodard on the ABC television series "Desperate Housewives".  The character is introduced in the last episodes of the series' first season, and becomes the center of the mystery of the second season, along with her two sons, Matthew and Caleb.

Crazy Eyes (character): Suzanne "Crazy Eyes" Warren is a fictional character played by Uzo Aduba on the Netflix series "Orange Is the New Black".  Warren is portrayed as intelligent, but lacking in social skills, and prone to spiral into emotional outbursts when agitated.  The character is the only role that has received Emmy Award recognition both in the comedy and drama genres from the same show and only the second character to earn Emmy recognition in both genres.  Aduba won the Emmy Award for Outstanding Guest Actress in a Comedy Series as well as the Critics' Choice Television Award for Best Guest Performer in a Comedy Series for her season one performance.  She received the Emmy Award for Outstanding Supporting Actress in a Drama Series as well as the Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Comedy Series for her season two performance.  Her season three performance again won Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Comedy Series.  She is a recurring character in season one and a regular character beginning with season two.

Jessica Chastain on screen and stage: Jessica Chastain is an American actress who has appeared in film, television and stage.  As a final-year student at the Juilliard School, she was signed on for a talent holding deal by the television producer John Wells.  From 2004 to 2010, she had guest roles in several television shows, including "ER", "Veronica Mars" and "".  She also appeared in stage productions with Michelle Williams for "The Cherry Orchard" in 2004, and with Al Pacino for "Salome" in 2006.  In 2008, Chastain made her film debut as the title character in "Jolene", an adaptation of E. L. Doctorow's short story "Jolene: A Life".  She had a minor role in "Stolen" (2009), a critically panned mystery-thriller, following which she played the younger version of Helen Mirren's character in "The Debt" (2010).

Angie Bolen: Angela de Luca, known in the series by the alias Angie Bolen, is a fictional character played by Drea de Matteo on the ABC television series "Desperate Housewives".  The character was created by television producer and screenwriter Marc Cherry and appeared throughout the series' sixth season from September 27, 2009 to May 16, 2010.  Cherry describes Angie as a "loving but tough Italian woman."  Her gritty and blunt demeanor contrasts from the domesticated leading characters.

Mary Drake: Mary Drake is a fictional character created by I. Marlene King and portrayed by Andrea Parker in the American television series "Pretty Little Liars".  "Pretty Little Liars" is a television adaptation of the novel series of the same name written by Sara Shepard, in which the antagonist Alison DiLaurentis has an identical twin sister, Courtney DiLaurentis.  It is believed that Mary is the on-screen counterpart of Courtney, though her recent characterization is more in line with Alison.  The character makes her first official introduction during the sixth-season finale "Hush, Hush, Sweet Liars".  The Liars discover that Mary is Jessica DiLaurentis' identical twin sister, a former patient at Radley Sanitarium who is Charlotte's biological mother.  In "The DArkest Knight", Drake is also revealed to be Spencer Hastings' biological mother.  During "Till Death Do Us Part", the elusive A.D. is revealed to be Alex Drake, Spencer's younger identical twin sister.  Alex believed the Liars knew who was accountable for Charlotte's murder and was also set on physically replacing Spencer due to being jealous of the life that she had.

Susan Mayer: Susan Mayer is a fictional character played by Teri Hatcher on the ABC television series "Desperate Housewives".  The character was created by television producer and screenwriter Marc Cherry.  She first appeared in the pilot episode of the series on October 3, 2004, and appeared in every episode until the series finale on May 13, 2012.  Susan resides on the fictional Wisteria Lane in Fairview, Eagle State, the primary setting of the show.  One of four lead characters, Susan is characterized as being a "notoriously clumsy" romantic with a "magnetic charm."  Her storylines tend to focus on her romantic relationships, most notably with Mike Delfino (James Denton), whom she marries twice in the series.

Martha Jones: Martha Jones is a fictional character played by Freema Agyeman in the long-running British science fiction television series "Doctor Who" and its spin-off series, "Torchwood".  She is a companion of the Tenth Doctor in "Doctor Who", after Rose Tyler (Billie Piper).  According to the character's creator and executive producer Russell T Davies in his non-fiction book "", the character was developed from the beginning with the intention of appearing for a whole of the 2007 series, and to later make guest appearances in subsequent series and crossover appearances in the show's two spin-offs; Martha subsequently made guest appearances in "Torchwood" series two and in "Doctor Who" series four in 2008 and special episode "The End of Time" in 2010.  Martha was also intended to make guest appearances in the 2009 series of "Torchwood" and "The Sarah Jane Adventures", but could not due to the actress's other obligations.

Carol Kane: Carolyn Laurie Kane (born June 18, 1952) is an American stage, screen and television actress and comedian.  She became known in the 1970s in films such as "Hester Street" (for which she received an Academy Award nomination) and "Annie Hall".  She appeared on the television series "Taxi" in the early 1980s, as the wife of Latka, the character played by Andy Kaufman, winning two Emmy Awards for her work.  She has played the character of Madame Morrible in the musical "Wicked", both in regional productions and on Broadway from 2005 to 2014.  Since 2015, she has been a main cast member on the Netflix original series "Unbreakable Kimmy Schmidt", in which she plays Lillian Kaushtupper.

Andrea Parker: Andrea Nicole Parker (born March 8, 1970) is an American television actress and former ballet dancer.  She is known for her roles on "ER", "The Pretender", "Less than Perfect", "Desperate Housewives", and "Pretty Little Liars".

Supporting paragraphs: Mary Drake Andrea Parker
Answer: "Pretty Little Liars"