Question: Who is best known for writing and directing science fiction films such as "Cube", "Cypher", "Nothing", and "Splice", Vincenzo Natali or Leigh Jason?

Context paragraphs:
Steve Hoban: Steven "Steve" Hoban (born 1964) is a Canadian film producer.  He has been nominated for three Genie Awards and won another.  He has collaborated with Vincenzo Natali, David Hewlett, and Chris Landreth on multiple films.  He is perhaps best known for "Splice" and the "Ginger Snaps" trilogy.

Cypher (film): Cypher (also known as Brainstorm), is a 2002 science fiction thriller film starring Jeremy Northam and Lucy Liu.  It was written by Brian King and directed by Vincenzo Natali.  Jeremy Northam plays an accountant whose hope for a career in corporate espionage takes an unexpected turn.  The film was shown in limited release in theaters in the US and Australia, and released on DVD on August 2, 2005.  The film received mixed reviews, and Northam received the Best Actor award at the Sitges Film Festival.

Vincenzo Natali: Vincenzo Natali (born January 6, 1969) is an American-Canadian film director and screenwriter, best known for writing and directing science fiction films such as "Cube", "Cypher", "Nothing", and "Splice".

History of science fiction films: The history of science fiction films parallels that of the motion picture industry as a whole, although it took several decades before the genre was taken seriously.  Since the 1960s, major science fiction films have succeeded in pulling in large audience shares, and films of this genre have become a regular staple of the film industry.  Science fiction films have led the way in special effects technology, and have also been used as a vehicle for social commentary.

List of science fiction films of the 1960s: A list of science fiction films released in the 1960s.  These films include core elements of science fiction, but can cross into other genres.  They have been released to a cinema audience by the commercial film industry and are widely distributed with reviews by reputable critics.  Collectively, the science fiction films from the 1960s received five Academy Awards, a Hugo Award and a BAFTA Award.

Cube (film series): Cube is a Canadian psychological thriller horror film series.  The three films were directed by Vincenzo Natali, Andrzej Sekuła, and Ernie Barbarash respectively.

Leigh Jason: Leigh Jason (July 26, 1904 – February 19, 1979) was an American film director and screenwriter.  He was born in New York, New York, and died in Woodland Hills, Los Angeles.

List of science fiction films of the 2000s: This is a list of science fiction films released in the 2000s.  These films include core elements of science fiction, but can cross into other genres.  They have been released to a cinema audience by the commercial film industry and are widely distributed with reviews by reputable critics.  Collectively, the science fiction films from the 2000s have received six Academy Awards, twenty Saturn Awards, two Hugo Awards, one Nebula Award, five BAFTA awards, and six Magritte Awards. However, these films also received 17 Golden Raspberry Awards.

Science fiction film: Science fiction film (or sci-fi) is a genre that uses speculative, fictional science-based depictions of phenomena that are not fully accepted by mainstream science, such as extraterrestrial lifeforms, alien worlds, extrasensory perception and time travel, along with futuristic elements such as spacecraft, robots, cyborgs, interstellar travel or other technologies.  Science fiction films have often been used to focus on political or social issues, and to explore philosophical issues like the human condition.  In many cases, tropes derived from written science fiction may be used by filmmakers ignorant of or at best indifferent to the standards of scientific plausibility and plot logic to which written science fiction is traditionally held.

Splice (film): Splice is a 2009 Canadian-French science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac.  The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes.  Guillermo del Toro, Don Murphy, and Joel Silver executive produced.

Supporting paragraphs: Vincenzo Natali Leigh Jason
Answer: Vincenzo Natali